pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/11339-0-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 7,565E-06 0,01848231 ! regulation of Rac protein signal transduction GO:0035020 18 8 1,000 7,565E-06 9,241E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 1,000 7,565E-06 6,161E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 1,215E-05 7,421E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 1,000 2,454E-05 0,01199054 GO:0046579|positive regulation of Ras protein signal transduction, ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 1,000 3,234E-05 0,01316802 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 4,604E-05 0,01606841 ! visual learning GO:0008542 38 19 1,000 4,604E-05 0,01405986 ! cellular response to unfolded protein GO:0034620 35 20 1,000 5,114E-05 0,01388186 GO:0030968|endoplasmic reticulum unfolded protein response, ! cell aging GO:0007569 48 22 1,000 6,214E-05 0,01517999 ! visual behavior GO:0007632 46 23 1,000 6,803E-05 0,01510946 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 8,731E-05 0,01777493 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 9,427E-05 0,01771459 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,015E-04 0,01770894 ! fat cell differentiation GO:0045444 57 28 1,000 1,015E-04 0,01652835 ! base-excision repair GO:0006284 41 28 1,000 1,015E-04 0,01549533 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 1,09E-04 0,01565913 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 1,09E-04 0,01478918 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 1,594E-04 0,02049383 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 1,881E-04 0,02298105 ! learning GO:0007612 82 40 1,000 2,086E-04 0,02426851 ! striated muscle cell differentiation GO:0051146 91 43 1,000 2,413E-04 0,02679277 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 2,644E-04 0,0280791 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 2,763E-04 0,02812331 ! response to insulin stimulus GO:0032868 98 47 1,000 2,885E-04 0,02818933 ! positive regulation of cell cycle GO:0045787 96 48 1,000 3,009E-04 0,02827459 ! response to calcium ion GO:0051592 94 49 1,000 3,136E-04 0,02837695 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 3,67E-04 0,03202284 ! regulation of translational initiation GO:0006446 87 54 1,000 3,81E-04 0,03209756 ! response to UV GO:0009411 120 55 1,000 3,953E-04 0,03218823 ! regulation of DNA replication GO:0006275 105 56 1,000 4,098E-04 0,03229331 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 4,245E-04 0,03241143 ! nucleotide-excision repair GO:0006289 91 57 1,000 4,245E-04 0,03142926 ! aging GO:0007568 112 58 1,000 4,396E-04 0,03158427 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 5,351E-04 0,03734816 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 6,038E-04 0,04097742 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 6,217E-04 0,04104699 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 6,767E-04 0,04350281 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 6,767E-04 0,04238736 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 7,146E-04 0,04364435 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 7,339E-04 0,04373249 ! learning or memory GO:0007611 161 76 1,000 7,535E-04 0,0438311 ! positive regulation of ligase activity GO:0051351 130 77 1,000 7,734E-04 0,04393942 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 8,138E-04 0,04518673 ! regulation of synaptic transmission GO:0050804 159 79 1,000 8,138E-04 0,04418258 ! muscle cell differentiation GO:0042692 178 81 1,000 8,553E-04 0,04542369 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 8,553E-04 0,04445723 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 8,978E-04 0,04569192 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 9,194E-04 0,04583653 ! regulation of ligase activity GO:0051340 147 84 1,000 9,194E-04 0,04491979 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 9,412E-04 0,04508584 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 9,412E-04 0,0442188 ! regulation of neurological system process GO:0031644 175 89 1,000 1,031E-03 0,04752868 ! response to inorganic substance GO:0010035 173 90 1,000 1,054E-03 0,04769353 ! positive regulation of protein modification process GO:0031401 156 90 1,000 1,054E-03 0,04682637 ! response to unfolded protein GO:0006986 139 90 1,000 1,054E-03 0,04599019 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 1,125E-03 0,04821718 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 158 96 1,000 1,198E-03 0,05046124 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 1,223E-03 0,05063418 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 1,248E-03 0,0508114 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 2,67E-03 0,10693283 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 2,67E-03 0,1052081 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 2,67E-03 0,10353813 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 2,67E-03 0,10192035 ! positive regulation of helicase activity GO:0051096 12 5 0,000 2,67E-03 0,10035234 ! neuron fate determination GO:0048664 7 5 0,000 2,67E-03 0,09883185 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,67E-03 0,09735675 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 2,67E-03 0,09592504 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 2,67E-03 0,09453482 ! polyol transport GO:0015791 12 5 0,000 2,67E-03 0,09318432 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 2,67E-03 0,09187186 ! response to superoxide GO:0000303 10 5 0,000 2,67E-03 0,09059587 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,67E-03 0,08935483 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 2,67E-03 0,08814733 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 2,67E-03 0,08697203 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 2,67E-03 0,08582766 ! female meiosis GO:0007143 10 5 0,000 2,67E-03 0,08471302 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 2,67E-03 0,08362695 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 2,67E-03 0,08256838 ! hypothalamus development GO:0021854 9 5 0,000 2,67E-03 0,08153628 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 2,67E-03 0,08052966 ! cobalt ion transport GO:0006824 11 5 0,000 2,67E-03 0,07954759 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 2,67E-03 0,07858919 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 2,67E-03 0,0776536 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 2,67E-03 0,07674003 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 2,67E-03 0,0758477 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 2,67E-03 0,07497589 ! embryonic camera-type eye development GO:0031076 12 5 0,000 2,67E-03 0,07412389 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 2,67E-03 0,07329104 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,67E-03 0,07247669 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 2,67E-03 0,07168025 ! transposition GO:0032196 9 5 0,000 2,67E-03 0,07090111 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 2,67E-03 0,07013874 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 2,67E-03 0,06939258 ! negative chemotaxis GO:0050919 16 5 0,000 2,67E-03 0,06866213 ! positive regulation of histone modification GO:0031058 6 5 0,000 2,67E-03 0,0679469 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 2,67E-03 0,06724642 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 2,67E-03 0,06656023 ! behavioral response to pain GO:0048266 10 5 0,000 2,67E-03 0,0658879 ! clathrin coat assembly GO:0048268 15 5 0,000 2,67E-03 0,06522902 ! Notch receptor processing GO:0007220 11 5 0,000 2,67E-03 0,06458319 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,67E-03 0,06395002 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 2,67E-03 0,06332915 ! micturition GO:0060073 9 5 0,000 2,67E-03 0,06272022 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 2,67E-03 0,06212288 ! copulation GO:0007620 9 5 0,000 2,67E-03 0,06153682 ! glial cell fate commitment GO:0021781 14 5 0,000 2,67E-03 0,0609617 ! protein maturation by protein folding GO:0022417 14 5 0,000 2,67E-03 0,06039724 ! bioluminescence GO:0008218 9 5 0,000 2,67E-03 0,05984314 ! spermidine metabolic process GO:0008216 7 5 0,000 2,67E-03 0,05929911 ! regulation of potassium ion transport GO:0043266 10 5 0,000 2,67E-03 0,05876489 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 2,67E-03 0,0582402 ! apoptotic cell clearance GO:0043277 23 5 0,000 2,67E-03 0,0577248 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 2,67E-03 0,05721844 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 2,67E-03 0,05672089 ! lipoprotein particle clearance GO:0034381 10 5 0,000 2,67E-03 0,05623192 ! grooming behavior GO:0007625 6 5 0,000 2,67E-03 0,0557513 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 2,67E-03 0,05527883 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 2,67E-03 0,05481431 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 2,67E-03 0,05435752 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,67E-03 0,05390828 ! response to protozoan GO:0001562 13 5 0,000 2,67E-03 0,05346641 ! positive regulation of glycolysis GO:0045821 13 5 0,000 2,67E-03 0,05303173 ! lymph vessel development GO:0001945 10 5 0,000 2,67E-03 0,05260405 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 2,67E-03 0,05218322 ! endochondral ossification GO:0001958 17 5 0,000 2,67E-03 0,05176907 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 2,67E-03 0,05136144 ! single strand break repair GO:0000012 8 5 0,000 2,67E-03 0,05096018 ! parathyroid gland development GO:0060017 14 5 0,000 2,67E-03 0,05056513 ! anagen GO:0042640 7 5 0,000 2,67E-03 0,05017617 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 2,67E-03 0,04979315 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 2,67E-03 0,04941593 ! cytokine secretion GO:0050663 15 5 0,000 2,67E-03 0,04904438 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 2,67E-03 0,04867838 ! ceramide catabolic process GO:0046514 7 5 0,000 2,67E-03 0,0483178 ! skeletal myofibril assembly GO:0014866 12 5 0,000 2,67E-03 0,04796252 ! smooth muscle tissue development GO:0048745 32 5 0,000 2,67E-03 0,04761243 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 2,67E-03 0,04726741 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 2,67E-03 0,04692736 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 2,67E-03 0,04659216 ! cardiac muscle fiber development GO:0048739 12 5 0,000 2,67E-03 0,04626172 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 2,67E-03 0,04593593 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 2,67E-03 0,0456147 ! neutrophil mediated immunity GO:0002446 7 5 0,000 2,67E-03 0,04529793 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 2,67E-03 0,04498553 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 2,67E-03 0,04467741 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 2,67E-03 0,04437349 ! glycine biosynthetic process GO:0006545 7 5 0,000 2,67E-03 0,04407366 ! microvillus organization GO:0032528 8 5 0,000 2,67E-03 0,04377787 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 2,67E-03 0,04348602 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 2,67E-03 0,04319803 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 2,67E-03 0,04291383 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 2,67E-03 0,04263335 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 2,67E-03 0,04235651 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 2,67E-03 0,04208324 ! polyol catabolic process GO:0046174 9 5 0,000 2,67E-03 0,04181348 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 2,67E-03 0,04154715 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 2,67E-03 0,04128419 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 2,67E-03 0,04102454 ! muscle cell migration GO:0014812 8 5 0,000 2,67E-03 0,04076814 ! mitochondrial fission GO:0000266 8 5 0,000 2,67E-03 0,04051492 ! sister chromatid cohesion GO:0007062 15 5 0,000 2,67E-03 0,04026483 ! response to tumor necrosis factor GO:0034612 10 5 0,000 2,67E-03 0,04001781 ! mRNA transcription GO:0009299 10 5 0,000 2,67E-03 0,0397738 ! nerve growth factor processing GO:0032455 9 5 0,000 2,67E-03 0,03953274 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 2,67E-03 0,03929459 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 2,67E-03 0,0390593 ! anaerobic glycolysis GO:0019642 6 5 0,000 2,67E-03 0,0388268 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 2,67E-03 0,03859706 ! monocyte activation GO:0042117 10 5 0,000 2,67E-03 0,03837001 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 2,67E-03 0,03814563 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 2,67E-03 0,03792385 ! response to food GO:0032094 6 5 0,000 2,67E-03 0,03770464 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 2,67E-03 0,03748794 ! positive regulation of transporter activity GO:0032411 8 5 0,000 2,67E-03 0,03727373 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 2,67E-03 0,03706195 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,67E-03 0,03685256 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 2,67E-03 0,03664552 ! forebrain neuron development GO:0021884 13 5 0,000 2,67E-03 0,0364408 ! lipoprotein catabolic process GO:0042159 11 5 0,000 2,67E-03 0,03623835 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 2,67E-03 0,03603813 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 2,67E-03 0,03584012 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 2,67E-03 0,03564428 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,67E-03 0,03545056 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 2,67E-03 0,03525893 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 2,67E-03 0,03506937 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 2,67E-03 0,03488183 ! lipid glycosylation GO:0030259 7 5 0,000 2,67E-03 0,03469629 ! nucleobase transport GO:0015851 6 5 0,000 2,67E-03 0,03451271 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,67E-03 0,03433107 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 2,67E-03 0,03415132 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 2,67E-03 0,03397345 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 2,67E-03 0,03379742 ! basic amino acid transport GO:0015802 12 5 0,000 2,67E-03 0,03362321 ! cellular glucose homeostasis GO:0001678 6 5 0,000 2,67E-03 0,03345078 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 2,67E-03 0,03328011 ! actin nucleation GO:0045010 11 5 0,000 2,67E-03 0,03311118 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,67E-03 0,03294395 ! depurination GO:0045007 5 5 0,000 2,67E-03 0,0327784 ! depyrimidination GO:0045008 10 5 0,000 2,67E-03 0,03261451 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 2,67E-03 0,03245225 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,67E-03 0,0322916 ! G2/M transition checkpoint GO:0031576 8 5 0,000 2,67E-03 0,03213252 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 2,67E-03 0,03197501 ! zinc ion homeostasis GO:0055069 9 5 0,000 2,67E-03 0,03181904 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 2,67E-03 0,03166457 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 2,67E-03 0,03151161 ! forebrain morphogenesis GO:0048853 13 5 0,000 2,67E-03 0,03136011 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 2,67E-03 0,03121006 ! activated T cell proliferation GO:0050798 16 5 0,000 2,67E-03 0,03106144 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 2,67E-03 0,03091423 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 2,67E-03 0,03076841 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,67E-03 0,03062395 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,67E-03 0,03048085 ! gamma-delta T cell activation GO:0046629 6 5 0,000 2,67E-03 0,03033908 ! response to arsenic GO:0046685 11 5 0,000 2,67E-03 0,03019862 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 2,67E-03 0,03005946 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 2,67E-03 0,02992157 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 2,67E-03 0,02978494 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 2,67E-03 0,02964956 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 2,67E-03 0,0295154 ! response to mercury ion GO:0046689 8 5 0,000 2,67E-03 0,02938244 ! response to cadmium ion GO:0046686 7 5 0,000 2,67E-03 0,02925068 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 2,67E-03 0,0291201 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 2,67E-03 0,02899068 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 2,67E-03 0,0288624 ! bile acid biosynthetic process GO:0006699 7 5 0,000 2,67E-03 0,02873525 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 2,67E-03 0,02860922 ! ganglioside catabolic process GO:0006689 12 5 0,000 2,67E-03 0,02848429 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 2,67E-03 0,02836045 ! decidualization GO:0046697 11 5 0,000 2,67E-03 0,02823767 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 2,67E-03 0,02811596 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 2,67E-03 0,02799529 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 2,67E-03 0,02787565 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 2,67E-03 0,02775703 ! embryonic cleavage GO:0040016 6 5 0,000 2,67E-03 0,02763942 ! peroxisome fission GO:0016559 5 5 0,000 2,67E-03 0,02752279 ! histone demethylation GO:0016577 13 5 0,000 2,67E-03 0,02740715 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 2,67E-03 0,02729248 ! mitotic recombination GO:0006312 9 5 0,000 2,67E-03 0,02717876 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 2,67E-03 0,02706599 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,67E-03 0,02695414 ! metaphase plate congression GO:0051310 7 5 0,000 2,67E-03 0,02684322 ! regulation of sterol transport GO:0032371 7 5 0,000 2,67E-03 0,02673321 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 2,67E-03 0,02662409 ! enteric nervous system development GO:0048484 8 5 0,000 2,67E-03 0,02651586 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 2,67E-03 0,02640851 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 2,67E-03 0,02630203 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 2,67E-03 0,0261964 ! muscle cell proliferation GO:0033002 12 5 0,000 2,67E-03 0,02609161 ! skeletal muscle regeneration GO:0043403 8 5 0,000 2,67E-03 0,02598766 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 2,67E-03 0,02588453 ! B cell homeostasis GO:0001782 13 5 0,000 2,67E-03 0,02578222 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 2,67E-03 0,02568072 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 2,67E-03 0,02558001 ! metaphase GO:0051323 11 5 0,000 2,67E-03 0,02548009 ! melatonin biosynthetic process GO:0030187 7 5 0,000 2,67E-03 0,02538094 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 2,67E-03 0,02528257 ! cellular response to nutrient GO:0031670 8 5 0,000 2,67E-03 0,02518495 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 2,67E-03 0,02508809 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 2,67E-03 0,02499196 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 2,67E-03 0,02489657 ! regulation of hair follicle development GO:0051797 10 5 0,000 2,67E-03 0,02480191 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 2,67E-03 0,02470796 ! response to redox state GO:0051775 6 5 0,000 2,67E-03 0,02461473 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 2,67E-03 0,02452219 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 2,67E-03 0,02443035 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 2,67E-03 0,02433919 ! brown fat cell differentiation GO:0050873 7 5 0,000 2,67E-03 0,02424871 ! regulation of telomerase activity GO:0051972 7 5 0,000 2,67E-03 0,0241589 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,67E-03 0,02406975 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 2,67E-03 0,02398126 ! porphyrin catabolic process GO:0006787 12 5 0,000 2,67E-03 0,02389342 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 2,67E-03 0,02380621 ! striatum development GO:0021756 14 5 0,000 2,67E-03 0,02371965 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 2,67E-03 0,0236337 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 2,67E-03 0,02354838 ! glial cell migration GO:0008347 10 5 0,000 2,67E-03 0,02346368 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 2,67E-03 0,02337958 ! neural plate morphogenesis GO:0001839 7 5 0,000 2,67E-03 0,02329608 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 2,67E-03 0,02321318 ! somatic stem cell maintenance GO:0035019 15 5 0,000 2,67E-03 0,02313086 ! T cell activation during immune response GO:0002286 9 5 0,000 2,67E-03 0,02304913 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 2,67E-03 0,02296797 ! negative regulation of lipase activity GO:0060192 8 5 0,000 2,67E-03 0,02288738 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 2,67E-03 0,02280735 ! neuroprotection GO:0043526 8 5 0,000 2,67E-03 0,02272788 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 2,67E-03 0,02264897 ! regulation of sensory perception GO:0051931 8 5 0,000 2,67E-03 0,0225706 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 2,67E-03 0,02249277 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 2,67E-03 0,02241547 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 2,67E-03 0,02233871 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 2,67E-03 0,02226247 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 2,67E-03 0,02218674 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 2,67E-03 0,02211153 ! sequestering of calcium ion GO:0051208 7 5 0,000 2,67E-03 0,02203683 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 2,67E-03 0,02196263 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 2,67E-03 0,02188893 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 2,67E-03 0,02181573 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 2,67E-03 0,02174301 ! spindle assembly GO:0051225 6 5 0,000 2,67E-03 0,02167077 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 2,67E-03 0,02159901 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 2,67E-03 0,02152773 ! protein palmitoylation GO:0018345 12 5 0,000 2,67E-03 0,02145692 ! drug metabolic process GO:0017144 7 5 0,000 2,67E-03 0,02138657 ! stem cell division GO:0017145 11 5 0,000 2,67E-03 0,02131667 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 2,67E-03 0,02124724 ! organ regeneration GO:0031100 7 5 0,000 2,67E-03 0,02117825 ! carnitine metabolic process GO:0009437 8 5 0,000 2,67E-03 0,02110972 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 2,67E-03 0,02104162 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 3,203E-03 0,02516238 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 3,203E-03 0,02508174 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 3,203E-03 0,0250016 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 3,203E-03 0,02492198 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 3,203E-03 0,02484286 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 3,203E-03 0,02476424 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 3,203E-03 0,02468612 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 3,203E-03 0,02460849 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 3,203E-03 0,02453135 ! response to oxygen radical GO:0000305 11 6 0,000 3,203E-03 0,02445469 ! positive regulation of axon extension GO:0045773 13 6 0,000 3,203E-03 0,02437851 ! myoblast cell fate commitment GO:0048625 18 6 0,000 3,203E-03 0,0243028 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 3,203E-03 0,02422756 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 3,203E-03 0,02415278 ! regulation of interferon-beta production GO:0032648 8 6 0,000 3,203E-03 0,02407847 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 3,203E-03 0,02400461 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 3,203E-03 0,0239312 ! forebrain regionalization GO:0021871 9 6 0,000 3,203E-03 0,02385824 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 3,203E-03 0,02378572 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 3,203E-03 0,02371364 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 3,203E-03 0,023642 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 3,203E-03 0,02357079 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 3,203E-03 0,0235 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 3,203E-03 0,02342964 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 3,203E-03 0,02335971 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 3,203E-03 0,02329018 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 3,203E-03 0,02322107 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 3,203E-03 0,02315237 ! malate metabolic process GO:0006108 13 6 0,000 3,203E-03 0,02308407 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 3,203E-03 0,02301618 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 3,203E-03 0,02294868 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 3,203E-03 0,02288158 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 3,203E-03 0,02281487 ! protein refolding GO:0042026 15 6 0,000 3,203E-03 0,02274855 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 3,203E-03 0,02268261 ! opsonization GO:0008228 8 6 0,000 3,203E-03 0,02261706 ! mating behavior GO:0007617 7 6 0,000 3,203E-03 0,02255188 ! erythrocyte maturation GO:0043249 8 6 0,000 3,203E-03 0,02248707 ! embryonic hemopoiesis GO:0035162 16 6 0,000 3,203E-03 0,02242264 ! protein amino acid dealkylation GO:0008214 15 6 0,000 3,203E-03 0,02235858 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 3,203E-03 0,02229488 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 3,203E-03 0,02223154 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 3,203E-03 0,02216856 ! response to interferon-gamma GO:0034341 16 6 0,000 3,203E-03 0,02210594 ! toxin metabolic process GO:0009404 11 6 0,000 3,203E-03 0,02204367 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 3,203E-03 0,02198175 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 3,203E-03 0,02192017 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 3,203E-03 0,02185894 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 3,203E-03 0,02179805 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 3,203E-03 0,0217375 ! cGMP-mediated signaling GO:0019934 14 6 0,000 3,203E-03 0,02167729 ! dorsal spinal cord development GO:0021516 10 6 0,000 3,203E-03 0,02161741 ! activation of MAPKKK activity GO:0000185 12 6 0,000 3,203E-03 0,02155786 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 3,203E-03 0,02149863 ! thymic T cell selection GO:0045061 16 6 0,000 3,203E-03 0,02143973 ! sphingoid catabolic process GO:0046521 8 6 0,000 3,203E-03 0,02138115 ! protein lipoylation GO:0009249 10 6 0,000 3,203E-03 0,02132289 ! transepithelial chloride transport GO:0030321 12 6 0,000 3,203E-03 0,02126495 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 3,203E-03 0,02120732 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 3,203E-03 0,02115 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 3,203E-03 0,021093 ! glutamate catabolic process GO:0006538 12 6 0,000 3,203E-03 0,02103629 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 3,203E-03 0,0209799 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 3,203E-03 0,0209238 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 3,203E-03 0,020868 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 3,203E-03 0,0208125 ! hyperosmotic response GO:0006972 10 6 0,000 3,203E-03 0,0207573 ! L-serine biosynthetic process GO:0006564 7 6 0,000 3,203E-03 0,02070238 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 3,203E-03 0,02064776 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 3,203E-03 0,02059342 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 3,203E-03 0,02053937 ! urea metabolic process GO:0019627 7 6 0,000 3,203E-03 0,02048561 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 3,203E-03 0,02043212 ! neutrophil activation GO:0042119 7 6 0,000 3,203E-03 0,02037891 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 3,203E-03 0,02032598 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 3,203E-03 0,02027332 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 3,203E-03 0,02022093 ! paraxial mesoderm development GO:0048339 16 6 0,000 3,203E-03 0,02016882 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 3,203E-03 0,02011697 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 3,203E-03 0,02006539 ! neuron apoptosis GO:0051402 15 6 0,000 3,203E-03 0,02001407 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 3,203E-03 0,01996301 ! T cell mediated immunity GO:0002456 17 6 0,000 3,203E-03 0,01991222 ! negative regulation of platelet activation GO:0010544 9 6 0,000 3,203E-03 0,01986168 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 3,203E-03 0,0198114 ! carnitine transport GO:0015879 10 6 0,000 3,203E-03 0,01976137 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 3,203E-03 0,01971159 ! positive regulation of exocytosis GO:0045921 11 6 0,000 3,203E-03 0,01966206 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 3,203E-03 0,01961279 ! early endosome to late endosome transport GO:0045022 16 6 0,000 3,203E-03 0,01956375 ! 5S class rRNA transcription GO:0042791 13 6 0,000 3,203E-03 0,01951497 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 3,203E-03 0,01946642 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 3,203E-03 0,01941812 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 3,203E-03 0,01937005 ! sodium ion homeostasis GO:0055078 12 6 0,000 3,203E-03 0,01932223 ! establishment of spindle localization GO:0051293 16 6 0,000 3,203E-03 0,01927463 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 3,203E-03 0,01922728 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 3,203E-03 0,01918015 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 3,203E-03 0,01913326 ! response to UV-C GO:0010225 14 6 0,000 3,203E-03 0,01908659 ! astrocyte development GO:0014002 16 6 0,000 3,203E-03 0,01904015 ! protein targeting to lysosome GO:0006622 12 6 0,000 3,203E-03 0,01899394 ! purine base biosynthetic process GO:0009113 17 6 0,000 3,203E-03 0,01894795 ! interaction with symbiont GO:0051702 14 6 0,000 3,203E-03 0,01890218 ! regulation of dendrite development GO:0050773 16 6 0,000 3,203E-03 0,01885663 ! peptidyl-arginine modification GO:0018195 13 6 0,000 3,203E-03 0,0188113 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 3,203E-03 0,01876619 ! response to copper ion GO:0046688 10 6 0,000 3,203E-03 0,0187213 ! response to exogenous dsRNA GO:0043330 13 6 0,000 3,203E-03 0,01867661 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 3,203E-03 0,01863215 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 3,203E-03 0,01858789 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 3,203E-03 0,01854384 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 3,203E-03 0,0185 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 3,203E-03 0,01845637 ! regulation of dopamine secretion GO:0014059 14 6 0,000 3,203E-03 0,01841294 ! nucleoside catabolic process GO:0009164 10 6 0,000 3,203E-03 0,01836972 ! hair follicle maturation GO:0048820 8 6 0,000 3,203E-03 0,0183267 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 3,203E-03 0,01828388 ! Schwann cell development GO:0014044 15 6 0,000 3,203E-03 0,01824126 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 3,203E-03 0,01819884 ! response to pheromone GO:0019236 6 6 0,000 3,203E-03 0,01815662 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 3,203E-03 0,01811459 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 3,203E-03 0,01807275 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 3,203E-03 0,01803111 ! base conversion or substitution editing GO:0016553 6 6 0,000 3,203E-03 0,01798966 ! subpallium development GO:0021544 15 6 0,000 3,203E-03 0,0179484 ! neural tube patterning GO:0021532 8 6 0,000 3,203E-03 0,01790733 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 3,203E-03 0,01786644 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 3,203E-03 0,01782574 ! maintenance of organ identity GO:0048496 9 6 0,000 3,203E-03 0,01778523 ! G2 phase GO:0051319 16 6 0,000 3,203E-03 0,0177449 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 3,203E-03 0,01770475 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 3,203E-03 0,01766479 ! oxygen homeostasis GO:0032364 10 6 0,000 3,203E-03 0,017625 ! establishment of planar polarity GO:0001736 7 6 0,000 3,203E-03 0,0175854 ! regulation of mast cell activation GO:0033003 13 6 0,000 3,203E-03 0,01754597 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 3,203E-03 0,01750671 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 3,203E-03 0,01746764 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 3,203E-03 0,01742873 ! receptor internalization GO:0031623 11 6 0,000 3,203E-03 0,01739 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 3,203E-03 0,01735144 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 3,203E-03 0,01731306 ! neutrophil homeostasis GO:0001780 11 6 0,000 3,203E-03 0,01727484 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 3,203E-03 0,01723679 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 3,203E-03 0,0171989 ! protein deubiquitination GO:0016579 16 6 0,000 3,203E-03 0,01716119 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 3,203E-03 0,01712364 ! protein destabilization GO:0031648 9 6 0,000 3,203E-03 0,01708625 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 3,203E-03 0,01704902 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 3,203E-03 0,01701196 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 3,203E-03 0,01697506 ! regulation of viral transcription GO:0046782 11 6 0,000 3,203E-03 0,01693831 ! progesterone metabolic process GO:0042448 12 6 0,000 3,203E-03 0,01690173 ! negative regulation of axon extension GO:0030517 24 6 0,000 3,203E-03 0,0168653 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 3,203E-03 0,01682904 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 3,203E-03 0,01679292 ! triglyceride catabolic process GO:0019433 10 6 0,000 3,203E-03 0,01675696 ! determination of adult lifespan GO:0008340 17 6 0,000 3,203E-03 0,01672116 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 3,203E-03 0,0166855 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 3,203E-03 0,01665 ! neural plate development GO:0001840 9 6 0,000 3,203E-03 0,01661465 ! catecholamine transport GO:0051937 9 6 0,000 3,203E-03 0,01657945 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 3,203E-03 0,0165444 ! sensory cilium assembly GO:0035058 10 6 0,000 3,203E-03 0,0165095 ! organ or tissue specific immune response GO:0002251 8 6 0,000 3,203E-03 0,01647474 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 3,203E-03 0,01644013 ! maternal placenta development GO:0001893 12 6 0,000 3,203E-03 0,01640566 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 3,203E-03 0,01637134 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 3,203E-03 0,01633716 ! negative regulation of B cell activation GO:0050869 14 6 0,000 3,203E-03 0,01630313 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 3,203E-03 0,01626923 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 3,203E-03 0,01623548 ! positive regulation of coagulation GO:0050820 13 6 0,000 3,203E-03 0,01620187 ! cellular anion homeostasis GO:0030002 11 6 0,000 3,203E-03 0,01616839 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 3,736E-03 0,01881947 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 3,736E-03 0,01878074 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 3,736E-03 0,01874218 ! behavioral response to cocaine GO:0048148 14 7 0,000 3,736E-03 0,01870377 ! regulation of helicase activity GO:0051095 16 7 0,000 3,736E-03 0,01866552 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 3,736E-03 0,01862743 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 3,736E-03 0,01858949 ! sleep GO:0030431 16 7 0,000 3,736E-03 0,01855171 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 3,736E-03 0,01851408 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 3,736E-03 0,0184766 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 3,736E-03 0,01843927 ! prostate gland development GO:0030850 14 7 0,000 3,736E-03 0,0184021 ! nucleotide-sugar transport GO:0015780 11 7 0,000 3,736E-03 0,01836507 ! synaptonemal complex assembly GO:0007130 10 7 0,000 3,736E-03 0,01832819 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 3,736E-03 0,01829146 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 3,736E-03 0,01825488 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 3,736E-03 0,01821844 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 3,736E-03 0,01818215 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 3,736E-03 0,01814601 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 3,736E-03 0,01811 ! SMAD protein complex assembly GO:0007183 13 7 0,000 3,736E-03 0,01807414 ! glycolipid transport GO:0046836 11 7 0,000 3,736E-03 0,01803842 ! protein amino acid sulfation GO:0006477 10 7 0,000 3,736E-03 0,01800284 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 3,736E-03 0,0179674 ! neuron adhesion GO:0007158 14 7 0,000 3,736E-03 0,0179321 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 3,736E-03 0,01789694 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 3,736E-03 0,01786192 ! establishment of tissue polarity GO:0007164 8 7 0,000 3,736E-03 0,01782703 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 3,736E-03 0,01779228 ! mRNA stabilization GO:0048255 18 7 0,000 3,736E-03 0,01775767 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 3,736E-03 0,01772319 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 3,736E-03 0,01768884 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 3,736E-03 0,01765462 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 3,736E-03 0,01762054 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 3,736E-03 0,01758659 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 3,736E-03 0,01755277 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 3,736E-03 0,01751908 ! lipoprotein transport GO:0042953 14 7 0,000 3,736E-03 0,01748552 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 3,736E-03 0,01745209 ! rhythmic behavior GO:0007622 17 7 0,000 3,736E-03 0,01741878 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 3,736E-03 0,0173856 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 3,736E-03 0,01735255 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 3,736E-03 0,01731962 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 3,736E-03 0,01728682 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 3,736E-03 0,01725414 ! regulation of odontogenesis GO:0042481 14 7 0,000 3,736E-03 0,01722159 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 3,736E-03 0,01718915 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 3,736E-03 0,01715684 ! mechanosensory behavior GO:0007638 16 7 0,000 3,736E-03 0,01712465 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 3,736E-03 0,01709259 ! positive regulation of isotype switching GO:0045830 17 7 0,000 3,736E-03 0,01706064 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 3,736E-03 0,01702881 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 3,736E-03 0,0169971 ! protein-cofactor linkage GO:0018065 13 7 0,000 3,736E-03 0,0169655 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 3,736E-03 0,01693403 ! spinal cord patterning GO:0021511 14 7 0,000 3,736E-03 0,01690267 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 3,736E-03 0,01687142 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 3,736E-03 0,0168403 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 3,736E-03 0,01680928 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 3,736E-03 0,01677838 ! adrenal gland development GO:0030325 17 7 0,000 3,736E-03 0,0167476 ! cysteine metabolic process GO:0006534 13 7 0,000 3,736E-03 0,01671692 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 3,736E-03 0,01668636 ! ovulation GO:0030728 10 7 0,000 3,736E-03 0,01665591 ! adenohypophysis development GO:0021984 11 7 0,000 3,736E-03 0,01662557 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 3,736E-03 0,01659535 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 3,736E-03 0,01656523 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 3,736E-03 0,01653522 ! microtubule nucleation GO:0007020 21 7 0,000 3,736E-03 0,01650532 ! proline biosynthetic process GO:0006561 10 7 0,000 3,736E-03 0,01647552 ! tryptophan metabolic process GO:0006568 11 7 0,000 3,736E-03 0,01644584 ! thyroid hormone generation GO:0006590 13 7 0,000 3,736E-03 0,01641626 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 3,736E-03 0,01638679 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 3,736E-03 0,01635742 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 3,736E-03 0,01632816 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 3,736E-03 0,016299 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 3,736E-03 0,01626995 ! galactose metabolic process GO:0006012 13 7 0,000 3,736E-03 0,016241 ! vesicle fusion GO:0006906 20 7 0,000 3,736E-03 0,01621215 ! response to dietary excess GO:0002021 8 7 0,000 3,736E-03 0,01618341 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 3,736E-03 0,01615476 ! intracellular pH reduction GO:0051452 13 7 0,000 3,736E-03 0,01612622 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 3,736E-03 0,01609778 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 3,736E-03 0,01606944 ! organ growth GO:0035265 15 7 0,000 3,736E-03 0,0160412 ! nucleoside transport GO:0015858 11 7 0,000 3,736E-03 0,01601305 ! nucleoside salvage GO:0043174 11 7 0,000 3,736E-03 0,01598501 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 3,736E-03 0,01595706 ! male sex determination GO:0030238 15 7 0,000 3,736E-03 0,01592922 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 3,736E-03 0,01590146 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 3,736E-03 0,01587381 ! parturition GO:0007567 16 7 0,000 3,736E-03 0,01584625 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 3,736E-03 0,01581879 ! rRNA modification GO:0000154 14 7 0,000 3,736E-03 0,01579142 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 3,736E-03 0,01576415 ! spindle checkpoint GO:0031577 16 7 0,000 3,736E-03 0,01573697 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 3,736E-03 0,01570988 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 3,736E-03 0,01568289 ! monocyte differentiation GO:0030224 16 7 0,000 3,736E-03 0,01565599 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 3,736E-03 0,01562918 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 3,736E-03 0,01560246 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 3,736E-03 0,01557584 ! hyaluronan metabolic process GO:0030212 9 7 0,000 3,736E-03 0,0155493 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 3,736E-03 0,01552286 ! anterograde axon cargo transport GO:0008089 18 7 0,000 3,736E-03 0,0154965 ! fibrinolysis GO:0042730 11 7 0,000 3,736E-03 0,01547024 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 3,736E-03 0,01544406 ! skeletal muscle contraction GO:0003009 8 7 0,000 3,736E-03 0,01541797 ! eating behavior GO:0042755 8 7 0,000 3,736E-03 0,01539197 ! B cell lineage commitment GO:0002326 21 7 0,000 3,736E-03 0,01536606 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 3,736E-03 0,01534024 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 3,736E-03 0,0153145 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 3,736E-03 0,01528885 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 3,736E-03 0,01526328 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 3,736E-03 0,0152378 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 3,736E-03 0,0152124 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 3,736E-03 0,01518709 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 3,736E-03 0,01516186 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 3,736E-03 0,01513672 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 3,736E-03 0,01511166 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 3,736E-03 0,01508668 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 3,736E-03 0,01506178 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 3,736E-03 0,01503697 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 3,736E-03 0,01501224 ! histone ubiquitination GO:0016574 9 7 0,000 3,736E-03 0,01498759 ! regulation of meiosis GO:0040020 12 7 0,000 3,736E-03 0,01496302 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 3,736E-03 0,01493853 ! T cell lineage commitment GO:0002360 16 7 0,000 3,736E-03 0,01491412 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 3,736E-03 0,01488979 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 3,736E-03 0,01486554 ! membrane to membrane docking GO:0022614 14 7 0,000 3,736E-03 0,01484137 ! transcription termination GO:0006353 14 7 0,000 3,736E-03 0,01481727 ! coenzyme A metabolic process GO:0015936 12 7 0,000 3,736E-03 0,01479326 ! anaphase GO:0051322 18 7 0,000 3,736E-03 0,01476932 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 3,736E-03 0,01474546 ! axonal fasciculation GO:0007413 19 7 0,000 3,736E-03 0,01472168 ! negative regulation of nuclear division GO:0051784 15 7 0,000 3,736E-03 0,01469797 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 3,736E-03 0,01467434 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 3,736E-03 0,01465079 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 3,736E-03 0,01462731 ! diuresis GO:0030146 12 7 0,000 3,736E-03 0,0146039 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 3,736E-03 0,01458058 ! thiamin metabolic process GO:0006772 7 7 0,000 3,736E-03 0,01455732 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 3,736E-03 0,01453414 ! antibiotic transport GO:0042891 9 7 0,000 3,736E-03 0,01451103 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 3,736E-03 0,014488 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 3,736E-03 0,01446504 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 3,736E-03 0,01444215 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 3,736E-03 0,01441934 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 3,736E-03 0,01439659 ! melanin biosynthetic process GO:0042438 10 7 0,000 3,736E-03 0,01437392 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 3,736E-03 0,01435132 ! dopamine biosynthetic process GO:0042416 18 7 0,000 3,736E-03 0,01432879 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 3,736E-03 0,01430633 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 3,736E-03 0,01428394 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 3,736E-03 0,01426163 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 3,736E-03 0,01423938 ! endosome to lysosome transport GO:0008333 12 7 0,000 3,736E-03 0,0142172 ! protein modification by small protein removal GO:0070646 19 7 0,000 3,736E-03 0,01419509 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 3,736E-03 0,01417304 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 3,736E-03 0,01415107 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 3,736E-03 0,01412916 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 3,736E-03 0,01410733 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 3,736E-03 0,01408556 ! muscle adaptation GO:0043500 13 7 0,000 3,736E-03 0,01406385 ! embryonic heart tube development GO:0035050 14 7 0,000 3,736E-03 0,01404222 ! retina homeostasis GO:0001895 12 7 0,000 3,736E-03 0,01402065 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 3,736E-03 0,01399914 ! protein amino acid prenylation GO:0018346 19 7 0,000 3,736E-03 0,0139777 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 3,736E-03 0,01395633 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 3,736E-03 0,01393502 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 4,269E-03 0,01589744 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 4,269E-03 0,01587324 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 4,269E-03 0,01584912 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 4,269E-03 0,01582507 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 4,269E-03 0,01580109 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 4,269E-03 0,01577719 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 4,269E-03 0,01575335 ! male meiosis GO:0007140 9 8 0,000 4,269E-03 0,01572959 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 4,269E-03 0,0157059 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 4,269E-03 0,01568229 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 4,269E-03 0,01565874 ! meiotic prophase I GO:0007128 14 8 0,000 4,269E-03 0,01563526 ! response to zinc ion GO:0010043 12 8 0,000 4,269E-03 0,01561186 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 4,269E-03 0,01558852 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 4,269E-03 0,01556525 ! oligopeptide transport GO:0006857 16 8 0,000 4,269E-03 0,01554206 ! actin-myosin filament sliding GO:0033275 13 8 0,000 4,269E-03 0,01551893 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 4,269E-03 0,01549587 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 4,269E-03 0,01547288 ! signal peptide processing GO:0006465 12 8 0,000 4,269E-03 0,01544996 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 4,269E-03 0,0154271 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 4,269E-03 0,01540431 ! macrophage chemotaxis GO:0048246 12 8 0,000 4,269E-03 0,01538159 ! succinate metabolic process GO:0006105 17 8 0,000 4,269E-03 0,01535894 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 4,269E-03 0,01533635 ! membrane hyperpolarization GO:0060081 11 8 0,000 4,269E-03 0,01531383 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 4,269E-03 0,01529138 ! estrogen metabolic process GO:0008210 17 8 0,000 4,269E-03 0,01526899 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 4,269E-03 0,01524667 ! T-helper 1 type immune response GO:0042088 12 8 0,000 4,269E-03 0,01522441 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 4,269E-03 0,01520222 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 4,269E-03 0,01518009 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 4,269E-03 0,01515802 ! reflex GO:0060004 17 8 0,000 4,269E-03 0,01513602 ! endothelial cell differentiation GO:0045446 17 8 0,000 4,269E-03 0,01511409 ! glycerolipid catabolic process GO:0046503 14 8 0,000 4,269E-03 0,01509221 ! hemoglobin metabolic process GO:0020027 14 8 0,000 4,269E-03 0,01507041 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 4,269E-03 0,01504866 ! pigment granule organization GO:0048753 17 8 0,000 4,269E-03 0,01502697 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 4,269E-03 0,01500535 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 4,269E-03 0,01498379 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 4,269E-03 0,0149623 ! astrocyte differentiation GO:0048708 19 8 0,000 4,269E-03 0,01494086 ! histidine catabolic process GO:0006548 10 8 0,000 4,269E-03 0,01491949 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 4,269E-03 0,01489817 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 4,269E-03 0,01487692 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 4,269E-03 0,01485573 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 4,269E-03 0,0148346 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 4,269E-03 0,01481352 ! regulation of pigmentation during development GO:0048070 25 8 0,000 4,269E-03 0,01479251 ! melanin metabolic process GO:0006582 17 8 0,000 4,269E-03 0,01477156 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 4,269E-03 0,01475067 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 4,269E-03 0,01472983 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 4,269E-03 0,01470906 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 4,269E-03 0,01468834 ! macrophage activation GO:0042116 13 8 0,000 4,269E-03 0,01466768 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 4,269E-03 0,01464708 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 4,269E-03 0,01462654 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 4,269E-03 0,01460605 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 4,269E-03 0,01458562 ! purine salvage GO:0043101 12 8 0,000 4,269E-03 0,01456525 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 4,269E-03 0,01454494 ! regulation of vascular permeability GO:0043114 12 8 0,000 4,269E-03 0,01452468 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 4,269E-03 0,01450448 ! osteoblast development GO:0002076 17 8 0,000 4,269E-03 0,01448433 ! positive regulation of vasodilation GO:0045909 14 8 0,000 4,269E-03 0,01446424 ! negative regulation of translational initiation GO:0045947 12 8 0,000 4,269E-03 0,01444421 ! Schwann cell differentiation GO:0014037 21 8 0,000 4,269E-03 0,01442423 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 4,269E-03 0,01440431 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 4,269E-03 0,01438444 ! response to UV-B GO:0010224 17 8 0,000 4,269E-03 0,01436463 ! protein targeting to vacuole GO:0006623 14 8 0,000 4,269E-03 0,01434487 ! protein retention in ER lumen GO:0006621 14 8 0,000 4,269E-03 0,01432517 ! intermediate filament organization GO:0045109 12 8 0,000 4,269E-03 0,01430551 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 4,269E-03 0,01428592 ! cellular extravasation GO:0045123 13 8 0,000 4,269E-03 0,01426638 ! cardiac muscle cell development GO:0055013 14 8 0,000 4,269E-03 0,01424689 ! response to antibiotic GO:0046677 11 8 0,000 4,269E-03 0,01422745 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 4,269E-03 0,01420807 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 4,269E-03 0,01418874 ! DNA topological change GO:0006265 12 8 0,000 4,269E-03 0,01416946 ! response to tropane GO:0014073 15 8 0,000 4,269E-03 0,01415023 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 4,269E-03 0,01413106 ! melanosome transport GO:0032402 13 8 0,000 4,269E-03 0,01411194 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 4,269E-03 0,01409287 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 4,269E-03 0,01407385 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 4,269E-03 0,01405488 ! mast cell activation GO:0045576 14 8 0,000 4,269E-03 0,01403596 ! multicellular organismal aging GO:0010259 20 8 0,000 4,269E-03 0,0140171 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 4,269E-03 0,01399828 ! gas homeostasis GO:0033483 14 8 0,000 4,269E-03 0,01397952 ! dendrite morphogenesis GO:0048813 14 8 0,000 4,269E-03 0,0139608 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 4,269E-03 0,01394214 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 4,269E-03 0,01392353 ! nucleosome disassembly GO:0006337 14 8 0,000 4,269E-03 0,01390496 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 4,269E-03 0,01388645 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 4,269E-03 0,01386798 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 4,269E-03 0,01384956 ! establishment of chromosome localization GO:0051303 14 8 0,000 4,269E-03 0,01383119 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 4,269E-03 0,01381287 ! intracellular lipid transport GO:0032365 16 8 0,000 4,269E-03 0,0137946 ! response to tumor cell GO:0002347 16 8 0,000 4,269E-03 0,01377638 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 4,269E-03 0,01375821 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 4,269E-03 0,01374008 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 4,269E-03 0,013722 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 4,269E-03 0,01370397 ! positive regulation of epidermis development GO:0045684 13 8 0,000 4,269E-03 0,01368598 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 4,269E-03 0,01366805 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 4,269E-03 0,01365016 ! hormone catabolic process GO:0042447 17 8 0,000 4,269E-03 0,01363231 ! glycolipid catabolic process GO:0019377 16 8 0,000 4,269E-03 0,01361452 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 4,269E-03 0,01359677 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 4,269E-03 0,01357906 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 4,269E-03 0,0135614 ! positive regulation of glucose import GO:0046326 8 8 0,000 4,269E-03 0,01354379 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 4,269E-03 0,01352623 ! adult feeding behavior GO:0008343 10 8 0,000 4,269E-03 0,01350871 ! ATP catabolic process GO:0006200 11 8 0,000 4,269E-03 0,01349123 ! blastocyst growth GO:0001832 19 8 0,000 4,269E-03 0,0134738 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 4,269E-03 0,01345641 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 4,269E-03 0,01343907 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 4,269E-03 0,01342178 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 4,269E-03 0,01340452 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 4,269E-03 0,01338732 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 4,269E-03 0,01337015 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 4,269E-03 0,01335304 ! amino sugar catabolic process GO:0046348 11 8 0,000 4,269E-03 0,01333596 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 4,269E-03 0,01331893 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 4,269E-03 0,01330194 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 4,269E-03 0,01328499 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 4,269E-03 0,01326809 ! behavioral response to nicotine GO:0035095 12 8 0,000 4,269E-03 0,01325123 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 4,269E-03 0,01323442 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 4,269E-03 0,01321764 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 4,269E-03 0,01320091 ! NAD biosynthetic process GO:0009435 17 8 0,000 4,269E-03 0,01318422 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 4,269E-03 0,01316758 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 4,269E-03 0,01315097 ! axon extension GO:0048675 16 9 0,000 4,801E-03 0,01477247 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 4,801E-03 0,01475389 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 4,801E-03 0,01473535 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 4,801E-03 0,01471686 ! pentose-phosphate shunt GO:0006098 16 9 0,000 4,801E-03 0,01469842 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 4,801E-03 0,01468003 ! cell proliferation in forebrain GO:0021846 18 9 0,000 4,801E-03 0,01466168 ! neutral lipid catabolic process GO:0046461 14 9 0,000 4,801E-03 0,01464337 ! reproductive behavior GO:0019098 22 9 0,000 4,801E-03 0,01462511 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 4,801E-03 0,0146069 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 4,801E-03 0,01458873 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 4,801E-03 0,01457061 ! UTP metabolic process GO:0046051 10 9 0,000 4,801E-03 0,01455253 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 4,801E-03 0,0145345 ! induction of positive chemotaxis GO:0050930 17 9 0,000 4,801E-03 0,01451651 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 4,801E-03 0,01449857 ! artery development GO:0060840 25 9 0,000 4,801E-03 0,01448067 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 4,801E-03 0,01446281 ! regulation of glycolysis GO:0006110 20 9 0,000 4,801E-03 0,014445 ! cerebral cortex cell migration GO:0021795 18 9 0,000 4,801E-03 0,01442723 ! equilibrioception GO:0050957 20 9 0,000 4,801E-03 0,01440951 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 4,801E-03 0,01439183 ! chemosensory behavior GO:0007635 21 9 0,000 4,801E-03 0,01437419 ! microtubule bundle formation GO:0001578 22 9 0,000 4,801E-03 0,0143566 ! middle ear morphogenesis GO:0042474 14 9 0,000 4,801E-03 0,01433905 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 4,801E-03 0,01432154 ! leukocyte degranulation GO:0043299 16 9 0,000 4,801E-03 0,01430407 ! ganglioside metabolic process GO:0001573 22 9 0,000 4,801E-03 0,01428665 ! negative regulation of endocytosis GO:0045806 12 9 0,000 4,801E-03 0,01426927 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 4,801E-03 0,01425193 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 4,801E-03 0,01423464 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 4,801E-03 0,01421738 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 4,801E-03 0,01420017 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 4,801E-03 0,014183 ! protein targeting to ER GO:0045047 25 9 0,000 4,801E-03 0,01416587 ! ceramide biosynthetic process GO:0046513 20 9 0,000 4,801E-03 0,01414878 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 4,801E-03 0,01413174 ! T cell selection GO:0045058 27 9 0,000 4,801E-03 0,01411473 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 4,801E-03 0,01409777 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 4,801E-03 0,01408084 ! glycine catabolic process GO:0006546 15 9 0,000 4,801E-03 0,01406396 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 4,801E-03 0,01404711 ! endosome organization GO:0007032 20 9 0,000 4,801E-03 0,01403031 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 4,801E-03 0,01401355 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 4,801E-03 0,01399683 ! regulation of type I interferon production GO:0032479 12 9 0,000 4,801E-03 0,01398014 ! mannose metabolic process GO:0006013 13 9 0,000 4,801E-03 0,0139635 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 4,801E-03 0,0139469 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 4,801E-03 0,01393033 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 4,801E-03 0,01391381 ! Rac protein signal transduction GO:0016601 20 9 0,000 4,801E-03 0,01389732 ! receptor clustering GO:0043113 20 9 0,000 4,801E-03 0,01388088 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 4,801E-03 0,01386447 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 4,801E-03 0,0138481 ! retinol metabolic process GO:0042572 20 9 0,000 4,801E-03 0,01383177 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 4,801E-03 0,01381548 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 4,801E-03 0,01379922 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 4,801E-03 0,01378301 ! macrophage differentiation GO:0030225 15 9 0,000 4,801E-03 0,01376683 ! oligodendrocyte development GO:0014003 11 9 0,000 4,801E-03 0,01375069 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 4,801E-03 0,01373459 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 4,801E-03 0,01371853 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 4,801E-03 0,0137025 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 4,801E-03 0,01368651 ! response to amine stimulus GO:0014075 13 9 0,000 4,801E-03 0,01367056 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 4,801E-03 0,01365465 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 4,801E-03 0,01363877 ! erythrocyte development GO:0048821 17 9 0,000 4,801E-03 0,01362293 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 4,801E-03 0,01360712 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 4,801E-03 0,01359136 ! renal water homeostasis GO:0003091 15 9 0,000 4,801E-03 0,01357563 ! postreplication repair GO:0006301 25 9 0,000 4,801E-03 0,01355993 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 4,801E-03 0,01354427 ! icosanoid secretion GO:0032309 15 9 0,000 4,801E-03 0,01352865 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 4,801E-03 0,01351307 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 4,801E-03 0,01349752 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 4,801E-03 0,013482 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 4,801E-03 0,01346652 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 4,801E-03 0,01345108 ! sterol catabolic process GO:0016127 14 9 0,000 4,801E-03 0,01343567 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 4,801E-03 0,0134203 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 4,801E-03 0,01340496 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 4,801E-03 0,01338966 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 4,801E-03 0,01337439 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 4,801E-03 0,01335916 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 4,801E-03 0,01334396 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 4,801E-03 0,0133288 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 4,801E-03 0,01331367 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 4,801E-03 0,01329857 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 4,801E-03 0,01328351 ! regulation of synaptogenesis GO:0051963 15 9 0,000 4,801E-03 0,01326849 ! purine base metabolic process GO:0006144 25 9 0,000 4,801E-03 0,01325349 ! pigment granule transport GO:0051904 17 9 0,000 4,801E-03 0,01323853 ! regulation of telomere maintenance GO:0032204 17 9 0,000 4,801E-03 0,01322361 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 4,801E-03 0,01320872 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 4,801E-03 0,01319386 ! regulation of muscle adaptation GO:0043502 14 9 0,000 4,801E-03 0,01317903 ! regulation of amino acid transport GO:0051955 12 9 0,000 4,801E-03 0,01316424 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 4,801E-03 0,01314949 ! mitochondrion localization GO:0051646 18 9 0,000 4,801E-03 0,01313476 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 5,333E-03 0,01457416 ! regulation of developmental growth GO:0048638 16 10 0,000 5,333E-03 0,01455788 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 5,333E-03 0,01454163 ! autophagic vacuole formation GO:0000045 17 10 0,000 5,333E-03 0,01452542 ! negative regulation of blood pressure GO:0045776 26 10 0,000 5,333E-03 0,01450925 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 5,333E-03 0,01449311 ! associative learning GO:0008306 21 10 0,000 5,333E-03 0,014477 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 5,333E-03 0,01446094 ! regulation of phosphatase activity GO:0010921 28 10 0,000 5,333E-03 0,0144449 ! phosphate transport GO:0006817 24 10 0,000 5,333E-03 0,01442891 ! cell volume homeostasis GO:0006884 17 10 0,000 5,333E-03 0,01441295 ! CTP metabolic process GO:0046036 11 10 0,000 5,333E-03 0,01439702 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 5,333E-03 0,01438113 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 5,333E-03 0,01436527 ! GTP metabolic process GO:0046039 11 10 0,000 5,333E-03 0,01434945 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 5,333E-03 0,01433367 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 5,333E-03 0,01431792 ! social behavior GO:0035176 29 10 0,000 5,333E-03 0,0143022 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 5,333E-03 0,01428652 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 5,333E-03 0,01427087 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 5,333E-03 0,01425525 ! androgen metabolic process GO:0008209 17 10 0,000 5,333E-03 0,01423968 ! phospholipid efflux GO:0033700 19 10 0,000 5,333E-03 0,01422413 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 5,333E-03 0,01420862 ! bile acid and bile salt transport GO:0015721 15 10 0,000 5,333E-03 0,01419314 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 5,333E-03 0,0141777 ! positive regulation of heart contraction GO:0045823 17 10 0,000 5,333E-03 0,01416229 ! lung alveolus development GO:0048286 26 10 0,000 5,333E-03 0,01414691 ! pathogenesis GO:0009405 17 10 0,000 5,333E-03 0,01413156 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 5,333E-03 0,01411625 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 5,333E-03 0,01410098 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 5,333E-03 0,01408573 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 5,333E-03 0,01407052 ! endoderm development GO:0007492 18 10 0,000 5,333E-03 0,01405534 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 5,333E-03 0,0140402 ! arginine catabolic process GO:0006527 17 10 0,000 5,333E-03 0,01402508 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 5,333E-03 0,01401 ! proline metabolic process GO:0006560 13 10 0,000 5,333E-03 0,01399495 ! glucan biosynthetic process GO:0009250 14 10 0,000 5,333E-03 0,01397994 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 5,333E-03 0,01396495 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 5,333E-03 0,01395 ! V(D)J recombination GO:0033151 34 10 0,000 5,333E-03 0,01393508 ! reverse cholesterol transport GO:0043691 19 10 0,000 5,333E-03 0,0139202 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 5,333E-03 0,01390534 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 5,333E-03 0,01389051 ! B cell proliferation GO:0042100 19 10 0,000 5,333E-03 0,01387572 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 5,333E-03 0,01386096 ! regulation of sodium ion transport GO:0002028 26 10 0,000 5,333E-03 0,01384623 ! multicellular organism growth GO:0035264 19 10 0,000 5,333E-03 0,01383153 ! phagocytosis, engulfment GO:0006911 33 10 0,000 5,333E-03 0,01381686 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 5,333E-03 0,01380223 ! ruffle organization GO:0031529 17 10 0,000 5,333E-03 0,01378762 ! epithelial cell development GO:0002064 21 10 0,000 5,333E-03 0,01377305 ! lens development in camera-type eye GO:0002088 17 10 0,000 5,333E-03 0,0137585 ! retinoic acid metabolic process GO:0042573 14 10 0,000 5,333E-03 0,01374399 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 5,333E-03 0,01372951 ! positive regulation of translational initiation GO:0045948 12 10 0,000 5,333E-03 0,01371506 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 5,333E-03 0,01370063 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 5,333E-03 0,01368624 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 5,333E-03 0,01367188 ! motor axon guidance GO:0008045 22 10 0,000 5,333E-03 0,01365755 ! copper ion homeostasis GO:0055070 13 10 0,000 5,333E-03 0,01364325 ! regulation of bone resorption GO:0045124 25 10 0,000 5,333E-03 0,01362898 ! protein heterooligomerization GO:0051291 17 10 0,000 5,333E-03 0,01361474 ! regulation of gliogenesis GO:0014013 23 10 0,000 5,333E-03 0,01360052 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 5,333E-03 0,01358634 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 5,333E-03 0,01357219 ! segment specification GO:0007379 15 10 0,000 5,333E-03 0,01355807 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 5,333E-03 0,01354397 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 5,333E-03 0,01352991 ! blastoderm segmentation GO:0007350 19 10 0,000 5,333E-03 0,01351587 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 5,333E-03 0,01350187 ! response to dsRNA GO:0043331 23 10 0,000 5,333E-03 0,01348789 ! DNA ligation GO:0006266 18 10 0,000 5,333E-03 0,01347394 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 5,333E-03 0,01346002 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 5,333E-03 0,01344613 ! melanosome localization GO:0032400 16 10 0,000 5,333E-03 0,01343227 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 5,333E-03 0,01341844 ! regulation of B cell differentiation GO:0045577 24 10 0,000 5,333E-03 0,01340463 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 5,333E-03 0,01339086 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 5,333E-03 0,01337711 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 5,333E-03 0,01336339 ! induction of an organ GO:0001759 17 10 0,000 5,333E-03 0,0133497 ! leukocyte activation during immune response GO:0002366 15 10 0,000 5,333E-03 0,01333603 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 5,333E-03 0,0133224 ! protein sumoylation GO:0016925 17 10 0,000 5,333E-03 0,01330879 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 5,333E-03 0,01329521 ! hindbrain morphogenesis GO:0021575 19 10 0,000 5,333E-03 0,01328165 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 5,333E-03 0,01326813 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 5,333E-03 0,01325463 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 5,333E-03 0,01324116 ! salivary gland development GO:0007431 28 10 0,000 5,333E-03 0,01322772 ! ubiquinone metabolic process GO:0006743 17 10 0,000 5,333E-03 0,0132143 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 5,333E-03 0,01320091 ! midbrain development GO:0030901 14 10 0,000 5,333E-03 0,01318755 ! musculoskeletal movement GO:0050881 16 10 0,000 5,333E-03 0,01317422 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 5,333E-03 0,01316091 ! methionine biosynthetic process GO:0009086 21 10 0,000 5,333E-03 0,01314763 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 5,333E-03 0,01313438 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 5,333E-03 0,01312115 ! quaternary ammonium group transport GO:0015697 22 10 0,000 5,333E-03 0,01310795 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 5,333E-03 0,01309478 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 5,333E-03 0,01308163 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 5,333E-03 0,01306851 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 5,333E-03 0,01305541 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 5,333E-03 0,01304235 ! establishment of pigment granule localization GO:0051905 18 10 0,000 5,333E-03 0,0130293 ! blastocyst formation GO:0001825 18 10 0,000 5,333E-03 0,01301629 ! regulation of fibrinolysis GO:0051917 20 10 0,000 5,333E-03 0,0130033 ! cerebellar cortex development GO:0021695 16 10 0,000 5,333E-03 0,01299033 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 5,333E-03 0,01297739 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 5,333E-03 0,01296448 ! response to nicotine GO:0035094 20 10 0,000 5,333E-03 0,01295159 ! negative regulation of immune effector process GO:0002698 23 10 0,000 5,333E-03 0,01293873 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 5,333E-03 0,0129259 ! negative regulation of muscle development GO:0048635 27 11 0,000 5,865E-03 0,0142008 ! respiratory burst GO:0045730 17 11 0,000 5,865E-03 0,01418674 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 5,865E-03 0,01417271 ! neuron fate specification GO:0048665 18 11 0,000 5,865E-03 0,0141587 ! telencephalon cell migration GO:0022029 23 11 0,000 5,865E-03 0,01414472 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 5,865E-03 0,01413078 ! thyroid gland development GO:0030878 26 11 0,000 5,865E-03 0,01411685 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 5,865E-03 0,01410296 ! synapsis GO:0007129 14 11 0,000 5,865E-03 0,01408909 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 5,865E-03 0,01407525 ! Golgi vesicle budding GO:0048194 26 11 0,000 5,865E-03 0,01406144 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 5,865E-03 0,01404765 ! response to pain GO:0048265 27 11 0,000 5,865E-03 0,01403389 ! detection of mechanical stimulus GO:0050982 22 11 0,000 5,865E-03 0,01402016 ! keratinocyte proliferation GO:0043616 19 11 0,000 5,865E-03 0,01400646 ! blood vessel remodeling GO:0001974 30 11 0,000 5,865E-03 0,01399278 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 5,865E-03 0,01397913 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 5,865E-03 0,0139655 ! bone resorption GO:0045453 16 11 0,000 5,865E-03 0,0139519 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 5,865E-03 0,01393833 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 5,865E-03 0,01392479 ! negative regulation of proteolysis GO:0045861 25 11 0,000 5,865E-03 0,01391127 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 5,865E-03 0,01389778 ! melanocyte differentiation GO:0030318 20 11 0,000 5,865E-03 0,01388431 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 5,865E-03 0,01387087 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 5,865E-03 0,01385745 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 5,865E-03 0,01384406 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 5,865E-03 0,0138307 ! regulation of intracellular pH GO:0051453 21 11 0,000 5,865E-03 0,01381736 ! substrate-bound cell migration GO:0006929 14 11 0,000 5,865E-03 0,01380405 ! UV protection GO:0009650 20 11 0,000 5,865E-03 0,01379077 ! adult heart development GO:0007512 16 11 0,000 5,865E-03 0,01377751 ! chondrocyte differentiation GO:0002062 27 11 0,000 5,865E-03 0,01376427 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 5,865E-03 0,01375106 ! macroautophagy GO:0016236 19 11 0,000 5,865E-03 0,01373788 ! temperature homeostasis GO:0001659 18 11 0,000 5,865E-03 0,01372472 ! behavioral fear response GO:0001662 27 11 0,000 5,865E-03 0,01371158 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 5,865E-03 0,01369848 ! negative regulation of ossification GO:0030279 27 11 0,000 5,865E-03 0,01368539 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 5,865E-03 0,01367233 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 5,865E-03 0,0136593 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 5,865E-03 0,01364629 ! alpha-beta T cell activation GO:0046631 26 11 0,000 5,865E-03 0,01363331 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 5,865E-03 0,01362035 ! regulation of organ growth GO:0046620 14 11 0,000 5,865E-03 0,01360741 ! pigment granule localization GO:0051875 20 11 0,000 5,865E-03 0,0135945 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 5,865E-03 0,01358162 ! vasoconstriction GO:0042310 20 11 0,000 5,865E-03 0,01356876 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 5,865E-03 0,01355592 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 5,865E-03 0,01354311 ! embryonic axis specification GO:0000578 19 11 0,000 5,865E-03 0,01353032 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 5,865E-03 0,01351755 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 5,865E-03 0,01350481 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 5,865E-03 0,0134921 ! nitric oxide metabolic process GO:0046209 17 11 0,000 5,865E-03 0,0134794 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 5,865E-03 0,01346674 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 5,865E-03 0,01345409 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 5,865E-03 0,01344147 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 5,865E-03 0,01342887 ! prophase GO:0051324 17 11 0,000 5,865E-03 0,0134163 ! neuroblast proliferation GO:0007405 25 11 0,000 5,865E-03 0,01340375 ! nucleosome positioning GO:0016584 15 11 0,000 5,865E-03 0,01339122 ! regulation of isotype switching GO:0045191 24 11 0,000 5,865E-03 0,01337872 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 5,865E-03 0,01336624 ! negative regulation of neurological system process GO:0031645 21 11 0,000 5,865E-03 0,01335378 ! apical protein localization GO:0045176 18 11 0,000 5,865E-03 0,01334135 ! acid secretion GO:0046717 20 11 0,000 5,865E-03 0,01332894 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 5,865E-03 0,01331655 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 5,865E-03 0,01330418 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 5,865E-03 0,01329184 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 5,865E-03 0,01327952 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 5,865E-03 0,01326723 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 5,865E-03 0,01325495 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 5,865E-03 0,0132427 ! cholesterol efflux GO:0033344 21 11 0,000 5,865E-03 0,01323048 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 5,865E-03 0,01321827 ! oocyte development GO:0048599 20 11 0,000 5,865E-03 0,01320609 ! negative regulation of glucose import GO:0046325 18 11 0,000 5,865E-03 0,01319393 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 5,865E-03 0,01318179 ! embryonic gut development GO:0048566 19 11 0,000 5,865E-03 0,01316967 ! regulation of organic acid transport GO:0032890 19 11 0,000 5,865E-03 0,01315758 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 5,865E-03 0,01314551 ! activation of innate immune response GO:0002218 16 11 0,000 5,865E-03 0,01313346 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 5,865E-03 0,01312143 ! cardiac cell differentiation GO:0035051 36 11 0,000 5,865E-03 0,01310943 ! lysogeny GO:0030069 22 11 0,000 5,865E-03 0,01309745 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 5,865E-03 0,01308548 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 5,865E-03 0,01307355 ! sequestering of metal ion GO:0051238 15 11 0,000 5,865E-03 0,01306163 ! regulation of embryonic development GO:0045995 35 11 0,000 5,865E-03 0,01304973 ! nucleus localization GO:0051647 22 11 0,000 5,865E-03 0,01303786 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 6,397E-03 0,01420659 ! positive regulation of blood pressure GO:0045777 18 12 0,000 6,397E-03 0,01419369 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 6,397E-03 0,01418081 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 6,397E-03 0,01416795 ! virus-host interaction GO:0019048 30 12 0,000 6,397E-03 0,01415512 ! regulation of B cell proliferation GO:0030888 22 12 0,000 6,397E-03 0,01414231 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 6,397E-03 0,01412952 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 6,397E-03 0,01411676 ! protein complex disassembly GO:0043241 28 12 0,000 6,397E-03 0,01410402 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 6,397E-03 0,0140913 ! regulation of cell projection assembly GO:0060491 33 12 0,000 6,397E-03 0,0140786 ! hippocampus development GO:0021766 29 12 0,000 6,397E-03 0,01406593 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 6,397E-03 0,01405328 ! cytokine biosynthetic process GO:0042089 23 12 0,000 6,397E-03 0,01404066 ! T cell proliferation GO:0042098 32 12 0,000 6,397E-03 0,01402805 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 6,397E-03 0,01401547 ! regulation of exit from mitosis GO:0007096 19 12 0,000 6,397E-03 0,01400291 ! ventral spinal cord development GO:0021517 25 12 0,000 6,397E-03 0,01399038 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 6,397E-03 0,01397786 ! drug transport GO:0015893 16 12 0,000 6,397E-03 0,01396537 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 6,397E-03 0,0139529 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 6,397E-03 0,01394046 ! tyrosine metabolic process GO:0006570 19 12 0,000 6,397E-03 0,01392803 ! polyamine metabolic process GO:0006595 18 12 0,000 6,397E-03 0,01391563 ! focal adhesion formation GO:0048041 37 12 0,000 6,397E-03 0,01390325 ! mitotic spindle organization GO:0007052 23 12 0,000 6,397E-03 0,01389089 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 6,397E-03 0,01387855 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 6,397E-03 0,01386624 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 6,397E-03 0,01385395 ! lipid digestion GO:0044241 21 12 0,000 6,397E-03 0,01384168 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 6,397E-03 0,01382943 ! entry into host cell GO:0030260 34 12 0,000 6,397E-03 0,0138172 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 6,397E-03 0,01380499 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 6,397E-03 0,01379281 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 6,397E-03 0,01378064 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 6,397E-03 0,0137685 ! protein targeting to peroxisome GO:0006625 27 12 0,000 6,397E-03 0,01375638 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 6,397E-03 0,01374428 ! regulation of phagocytosis GO:0050764 17 12 0,000 6,397E-03 0,01373221 ! snRNA metabolic process GO:0016073 30 12 0,000 6,397E-03 0,01372015 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 6,397E-03 0,01370812 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 6,397E-03 0,0136961 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 6,397E-03 0,01368411 ! cranial nerve development GO:0021545 23 12 0,000 6,397E-03 0,01367214 ! fucose catabolic process GO:0019317 25 12 0,000 6,397E-03 0,01366018 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 6,397E-03 0,01364825 ! histone acetylation GO:0016573 27 12 0,000 6,397E-03 0,01363634 ! mRNA polyadenylation GO:0006378 24 12 0,000 6,397E-03 0,01362446 ! autonomic nervous system development GO:0048483 24 12 0,000 6,397E-03 0,01361259 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 6,397E-03 0,01360074 ! zymogen activation GO:0031638 18 12 0,000 6,397E-03 0,01358891 ! peptidyl-lysine modification GO:0018205 21 12 0,000 6,397E-03 0,01357711 ! T cell homeostasis GO:0043029 28 12 0,000 6,397E-03 0,01356532 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 6,397E-03 0,01355356 ! glutathione biosynthetic process GO:0006750 15 12 0,000 6,397E-03 0,01354181 ! regulation of leukocyte migration GO:0002685 29 12 0,000 6,397E-03 0,01353009 ! oocyte differentiation GO:0009994 21 12 0,000 6,397E-03 0,01351838 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 6,397E-03 0,0135067 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 6,397E-03 0,01349504 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 6,397E-03 0,01348339 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 6,397E-03 0,01347177 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 6,397E-03 0,01346016 ! defense response to fungus GO:0050832 15 12 0,000 6,397E-03 0,01344858 ! developmental induction GO:0031128 22 12 0,000 6,397E-03 0,01343702 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 6,397E-03 0,01342547 ! lamellipodium assembly GO:0030032 24 12 0,000 6,397E-03 0,01341395 ! response to cold GO:0009409 17 12 0,000 6,397E-03 0,01340245 ! establishment of cell polarity GO:0030010 21 12 0,000 6,397E-03 0,01339096 ! regulation of synapse organization GO:0050807 18 12 0,000 6,397E-03 0,0133795 ! localization within membrane GO:0051668 26 12 0,000 6,397E-03 0,01336805 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 6,928E-03 0,01446602 ! cGMP metabolic process GO:0046068 18 13 0,000 6,928E-03 0,01445366 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 6,928E-03 0,01444133 ! regulation of chemokine production GO:0032642 18 13 0,000 6,928E-03 0,01442902 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 6,928E-03 0,01441673 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 6,928E-03 0,01440446 ! peroxisomal transport GO:0043574 28 13 0,000 6,928E-03 0,01439221 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 6,928E-03 0,01437998 ! cartilage condensation GO:0001502 22 13 0,000 6,928E-03 0,01436777 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 6,928E-03 0,01435559 ! organelle fusion GO:0048284 36 13 0,000 6,928E-03 0,01434342 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 6,928E-03 0,01433128 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 6,928E-03 0,01431915 ! pseudouridine synthesis GO:0001522 19 13 0,000 6,928E-03 0,01430705 ! endocrine pancreas development GO:0031018 25 13 0,000 6,928E-03 0,01429496 ! positive regulation of cell growth GO:0030307 24 13 0,000 6,928E-03 0,0142829 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 6,928E-03 0,01427086 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 6,928E-03 0,01425884 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 6,928E-03 0,01424683 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 6,928E-03 0,01423485 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 6,928E-03 0,01422289 ! methionine metabolic process GO:0006555 31 13 0,000 6,928E-03 0,01421095 ! plasma membrane organization GO:0007009 27 13 0,000 6,928E-03 0,01419903 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 6,928E-03 0,01418712 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 6,928E-03 0,01417524 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 6,928E-03 0,01416338 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 6,928E-03 0,01415154 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 6,928E-03 0,01413971 ! cytokine metabolic process GO:0042107 24 13 0,000 6,928E-03 0,01412791 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 6,928E-03 0,01411613 ! exocrine system development GO:0035272 34 13 0,000 6,928E-03 0,01410437 ! asymmetric protein localization GO:0008105 24 13 0,000 6,928E-03 0,01409262 ! membrane protein proteolysis GO:0033619 33 13 0,000 6,928E-03 0,0140809 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 6,928E-03 0,01406919 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 6,928E-03 0,01405751 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 6,928E-03 0,01404584 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 6,928E-03 0,01403419 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 6,928E-03 0,01402257 ! protein homotetramerization GO:0051289 24 13 0,000 6,928E-03 0,01401096 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 6,928E-03 0,01399937 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 6,928E-03 0,0139878 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 6,928E-03 0,01397625 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 6,928E-03 0,01396472 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 6,928E-03 0,01395321 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 6,928E-03 0,01394171 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 6,928E-03 0,01393024 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 6,928E-03 0,01391878 ! histone methylation GO:0016571 29 13 0,000 6,928E-03 0,01390734 ! chromatin silencing GO:0006342 29 13 0,000 6,928E-03 0,01389593 ! gland morphogenesis GO:0022612 31 13 0,000 6,928E-03 0,01388453 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 6,928E-03 0,01387315 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 6,928E-03 0,01386178 ! regulation of epidermis development GO:0045682 19 13 0,000 6,928E-03 0,01385044 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 6,928E-03 0,01383912 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 6,928E-03 0,01382781 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 6,928E-03 0,01381652 ! spleen development GO:0048536 24 13 0,000 6,928E-03 0,01380525 ! regulation of mRNA stability GO:0043488 32 13 0,000 6,928E-03 0,013794 ! digestive tract morphogenesis GO:0048546 31 13 0,000 6,928E-03 0,01378277 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 6,928E-03 0,01377155 ! anterior/posterior axis specification GO:0009948 22 13 0,000 6,928E-03 0,01376036 ! regulation of RNA splicing GO:0043484 22 13 0,000 6,928E-03 0,01374918 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 6,928E-03 0,01373802 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 6,928E-03 0,01372688 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 6,928E-03 0,01371575 ! mRNA 3'-end processing GO:0031124 25 13 0,000 6,928E-03 0,01370465 ! insulin secretion GO:0030073 24 13 0,000 6,928E-03 0,01369356 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 6,928E-03 0,01368249 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 6,928E-03 0,01367144 ! acrosome reaction GO:0007340 19 13 0,000 6,928E-03 0,0136604 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 6,928E-03 0,01364939 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 6,928E-03 0,01363839 ! rRNA transcription GO:0009303 28 14 0,000 7,459E-03 0,01467195 ! regulation of S phase GO:0033261 26 14 0,000 7,459E-03 0,01466015 ! water transport GO:0006833 21 14 0,000 7,459E-03 0,01464837 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 7,459E-03 0,0146366 ! non-recombinational repair GO:0000726 29 14 0,000 7,459E-03 0,01462485 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 7,459E-03 0,01461313 ! retina development in camera-type eye GO:0060041 28 14 0,000 7,459E-03 0,01460142 ! hair follicle morphogenesis GO:0031069 27 14 0,000 7,459E-03 0,01458973 ! RNA polyadenylation GO:0043631 32 14 0,000 7,459E-03 0,01457805 ! lipid localization GO:0010876 32 14 0,000 7,459E-03 0,0145664 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 7,459E-03 0,01455477 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 7,459E-03 0,01454315 ! regulated secretory pathway GO:0045055 24 14 0,000 7,459E-03 0,01453155 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 7,459E-03 0,01451997 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 7,459E-03 0,01450841 ! arginine metabolic process GO:0006525 21 14 0,000 7,459E-03 0,01449687 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 7,459E-03 0,01448535 ! cell-cell junction assembly GO:0007043 32 14 0,000 7,459E-03 0,01447384 ! regulation of heart rate GO:0002027 25 14 0,000 7,459E-03 0,01446236 ! fear response GO:0042596 34 14 0,000 7,459E-03 0,01445089 ! organic alcohol transport GO:0015850 29 14 0,000 7,459E-03 0,01443944 ! negative regulation of caspase activity GO:0043154 23 14 0,000 7,459E-03 0,014428 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 7,459E-03 0,01441659 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 7,459E-03 0,01440519 ! neutral amino acid transport GO:0015804 28 14 0,000 7,459E-03 0,01439381 ! bone mineralization GO:0030282 18 14 0,000 7,459E-03 0,01438245 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 7,459E-03 0,01437111 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 7,459E-03 0,01435979 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 7,459E-03 0,01434848 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 7,459E-03 0,01433719 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 7,459E-03 0,01432592 ! regulation of cellular pH GO:0030641 27 14 0,000 7,459E-03 0,01431466 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 7,459E-03 0,01430343 ! ribosome assembly GO:0042255 18 14 0,000 7,459E-03 0,01429221 ! cerebellum development GO:0021549 23 14 0,000 7,459E-03 0,01428101 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 7,459E-03 0,01426983 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 7,459E-03 0,01425866 ! negative regulation of protein secretion GO:0050709 30 14 0,000 7,459E-03 0,01424751 ! response to gamma radiation GO:0010332 30 14 0,000 7,459E-03 0,01423638 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 7,459E-03 0,01422527 ! NADP metabolic process GO:0006739 24 14 0,000 7,459E-03 0,01421417 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 7,459E-03 0,01420309 ! oxygen transport GO:0015671 22 14 0,000 7,459E-03 0,01419203 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 7,459E-03 0,01418099 ! male genitalia development GO:0030539 26 14 0,000 7,459E-03 0,01416996 ! regulation of RNA stability GO:0043487 33 14 0,000 7,459E-03 0,01415895 ! regulation of axon extension GO:0030516 43 14 0,000 7,459E-03 0,01414796 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 7,459E-03 0,01413698 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 7,459E-03 0,01412602 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 7,459E-03 0,01411508 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 7,99E-03 0,01510777 ! lactation GO:0007595 30 15 0,000 7,99E-03 0,01509609 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 7,99E-03 0,01508442 ! reproductive cellular process GO:0048610 22 15 0,000 7,99E-03 0,01507277 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 7,99E-03 0,01506114 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 7,99E-03 0,01504953 ! superoxide anion generation GO:0042554 22 15 0,000 7,99E-03 0,01503794 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 7,99E-03 0,01502636 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 7,99E-03 0,0150148 ! phospholipid catabolic process GO:0009395 27 15 0,000 7,99E-03 0,01500326 ! copper ion transport GO:0006825 22 15 0,000 7,99E-03 0,01499174 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 7,99E-03 0,01498023 ! cardiac muscle contraction GO:0060048 28 15 0,000 7,99E-03 0,01496874 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 7,99E-03 0,01495727 ! sulfate transport GO:0008272 27 15 0,000 7,99E-03 0,01494582 ! response to cAMP GO:0051591 25 15 0,000 7,99E-03 0,01493438 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 7,99E-03 0,01492297 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 7,99E-03 0,01491157 ! regulation of mRNA processing GO:0050684 26 15 0,000 7,99E-03 0,01490018 ! response to hexose stimulus GO:0009746 25 15 0,000 7,99E-03 0,01488882 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 7,99E-03 0,01487747 ! glycoprotein catabolic process GO:0006516 33 15 0,000 7,99E-03 0,01486614 ! vesicle coating GO:0006901 38 15 0,000 7,99E-03 0,01485483 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 7,99E-03 0,01484353 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 7,99E-03 0,01483225 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 7,99E-03 0,01482099 ! regulation of exocytosis GO:0017157 26 15 0,000 7,99E-03 0,01480974 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 7,99E-03 0,01479851 ! G1/S transition checkpoint GO:0031575 37 15 0,000 7,99E-03 0,0147873 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 7,99E-03 0,01477611 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 7,99E-03 0,01476493 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 7,99E-03 0,01475377 ! regulation of vasodilation GO:0042312 27 15 0,000 7,99E-03 0,01474263 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 7,99E-03 0,0147315 ! histone deacetylation GO:0016575 24 15 0,000 7,99E-03 0,01472039 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 7,99E-03 0,0147093 ! water homeostasis GO:0030104 28 15 0,000 7,99E-03 0,01469822 ! cofactor transport GO:0051181 30 15 0,000 7,99E-03 0,01468716 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 7,99E-03 0,01467612 ! muscle maintenance GO:0046716 26 15 0,000 7,99E-03 0,01466509 ! protein-chromophore linkage GO:0018298 25 15 0,000 7,99E-03 0,01465408 ! intestinal absorption GO:0050892 31 15 0,000 7,99E-03 0,01464309 ! dopamine metabolic process GO:0042417 35 15 0,000 7,99E-03 0,01463211 ! cAMP biosynthetic process GO:0006171 25 15 0,000 7,99E-03 0,01462115 ! heme biosynthetic process GO:0006783 33 15 0,000 7,99E-03 0,01461021 ! cell killing GO:0001906 32 15 0,000 7,99E-03 0,01459928 ! lymphocyte homeostasis GO:0002260 33 15 0,000 7,99E-03 0,01458837 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 7,99E-03 0,01457748 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 7,99E-03 0,0145666 ! L-fucose metabolic process GO:0042354 33 15 0,000 7,99E-03 0,01455573 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 7,99E-03 0,01454489 ! actin filament polymerization GO:0030041 27 15 0,000 7,99E-03 0,01453406 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 7,99E-03 0,01452324 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 8,52E-03 0,01547603 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 8,52E-03 0,01546453 ! positive regulation of cell size GO:0045793 29 16 0,000 8,52E-03 0,01545305 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 8,52E-03 0,01544158 ! dicarboxylic acid transport GO:0006835 47 16 0,000 8,52E-03 0,01543014 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 8,52E-03 0,01541871 ! bone remodeling GO:0046849 28 16 0,000 8,52E-03 0,0154073 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 8,52E-03 0,0153959 ! heterophilic cell adhesion GO:0007157 43 16 0,000 8,52E-03 0,01538452 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 8,52E-03 0,01537316 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 8,52E-03 0,01536181 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 8,52E-03 0,01535048 ! positive regulation of ion transport GO:0043270 23 16 0,000 8,52E-03 0,01533917 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 8,52E-03 0,01532788 ! startle response GO:0001964 28 16 0,000 8,52E-03 0,0153166 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 8,52E-03 0,01530534 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 8,52E-03 0,01529409 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 8,52E-03 0,01528286 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 8,52E-03 0,01527165 ! protein polyubiquitination GO:0000209 41 16 0,000 8,52E-03 0,01526045 ! glutamate metabolic process GO:0006536 25 16 0,000 8,52E-03 0,01524927 ! pituitary gland development GO:0021983 30 16 0,000 8,52E-03 0,01523811 ! response to osmotic stress GO:0006970 27 16 0,000 8,52E-03 0,01522696 ! lysosomal transport GO:0007041 31 16 0,000 8,52E-03 0,01521583 ! fructose metabolic process GO:0006000 25 16 0,000 8,52E-03 0,01520472 ! L-amino acid transport GO:0015807 33 16 0,000 8,52E-03 0,01519362 ! stem cell development GO:0048864 46 16 0,000 8,52E-03 0,01518254 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 8,52E-03 0,01517147 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 8,52E-03 0,01516042 ! intermediate filament-based process GO:0045103 36 16 0,000 8,52E-03 0,01514939 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 8,52E-03 0,01513837 ! negative regulation of immune response GO:0050777 38 16 0,000 8,52E-03 0,01512737 ! axon cargo transport GO:0008088 46 16 0,000 8,52E-03 0,01511638 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 8,52E-03 0,01510541 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 8,52E-03 0,01509446 ! DNA replication initiation GO:0006270 28 16 0,000 8,52E-03 0,01508352 ! neuron recognition GO:0008038 40 16 0,000 8,52E-03 0,0150726 ! mRNA splice site selection GO:0006376 44 16 0,000 8,52E-03 0,01506169 ! tissue regeneration GO:0042246 27 16 0,000 8,52E-03 0,0150508 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 8,52E-03 0,01503992 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 8,52E-03 0,01502907 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 8,52E-03 0,01501822 ! biomineral formation GO:0031214 22 16 0,000 8,52E-03 0,01500739 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 8,52E-03 0,01499658 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 8,52E-03 0,01498579 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 8,52E-03 0,014975 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 8,52E-03 0,01496424 ! regulation of ATPase activity GO:0043462 26 16 0,000 8,52E-03 0,01495349 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 8,52E-03 0,01494275 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 8,52E-03 0,01493203 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 8,52E-03 0,01492133 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 8,52E-03 0,01491064 ! peptide hormone processing GO:0016486 27 16 0,000 8,52E-03 0,01489997 ! positive regulation of cell killing GO:0031343 36 17 0,000 9,051E-03 0,01581589 ! metencephalon development GO:0022037 32 17 0,000 9,051E-03 0,01580459 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 9,051E-03 0,0157933 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 9,051E-03 0,01578202 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 9,051E-03 0,01577077 ! signal complex assembly GO:0007172 47 17 0,000 9,051E-03 0,01575953 ! filopodium assembly GO:0046847 42 17 0,000 9,051E-03 0,0157483 ! endothelial cell migration GO:0043542 31 17 0,000 9,051E-03 0,01573709 ! gene silencing by RNA GO:0031047 38 17 0,000 9,051E-03 0,0157259 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 9,051E-03 0,01571472 ! glial cell development GO:0021782 28 17 0,000 9,051E-03 0,01570356 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 9,051E-03 0,01569242 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 9,051E-03 0,01568129 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 9,051E-03 0,01567017 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 9,051E-03 0,01565908 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 9,051E-03 0,01564799 ! myoblast differentiation GO:0045445 50 17 0,000 9,051E-03 0,01563693 ! activation of MAPKK activity GO:0000186 43 17 0,000 9,051E-03 0,01562588 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 9,051E-03 0,01561484 ! regulation of survival gene product expression GO:0045884 38 17 0,000 9,051E-03 0,01560382 ! cardiac muscle tissue development GO:0048738 34 17 0,000 9,051E-03 0,01559282 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 9,051E-03 0,01558183 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 9,051E-03 0,01557086 ! complement activation, alternative pathway GO:0006957 19 17 0,000 9,051E-03 0,0155599 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 9,051E-03 0,01554896 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 9,051E-03 0,01553803 ! membrane budding GO:0006900 42 17 0,000 9,051E-03 0,01552712 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 9,051E-03 0,01551622 ! regulation of protein binding GO:0043393 33 17 0,000 9,051E-03 0,01550534 ! nucleobase metabolic process GO:0009112 43 17 0,000 9,051E-03 0,01549447 ! DNA unwinding during replication GO:0006268 26 17 0,000 9,051E-03 0,01548362 ! genitalia development GO:0048806 32 17 0,000 9,051E-03 0,01547279 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 9,051E-03 0,01546197 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 9,051E-03 0,01545116 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 9,051E-03 0,01544037 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 9,051E-03 0,0154296 ! neutrophil chemotaxis GO:0030593 29 17 0,000 9,051E-03 0,01541884 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 9,051E-03 0,01540809 ! steroid catabolic process GO:0006706 34 17 0,000 9,051E-03 0,01539736 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 9,051E-03 0,01538665 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 9,051E-03 0,01537595 ! gas transport GO:0015669 26 17 0,000 9,051E-03 0,01536526 ! organic cation transport GO:0015695 32 17 0,000 9,051E-03 0,01535459 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 9,051E-03 0,01534394 ! RNA 3'-end processing GO:0031123 37 17 0,000 9,051E-03 0,0153333 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 9,051E-03 0,01532267 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 9,581E-03 0,01620867 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 9,581E-03 0,01619745 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 9,581E-03 0,01618625 ! limbic system development GO:0021761 40 18 0,000 9,581E-03 0,01617506 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 9,581E-03 0,01616389 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 9,581E-03 0,01615274 ! adult walking behavior GO:0007628 36 18 0,000 9,581E-03 0,0161416 ! patterning of blood vessels GO:0001569 43 18 0,000 9,581E-03 0,01613047 ! heart looping GO:0001947 34 18 0,000 9,581E-03 0,01611936 ! ciliary or flagellar motility GO:0001539 32 18 0,000 9,581E-03 0,01610827 ! regulation of viral genome replication GO:0045069 30 18 0,000 9,581E-03 0,01609719 ! centrosome cycle GO:0007098 26 18 0,000 9,581E-03 0,01608613 ! positive regulation of proteolysis GO:0045862 36 18 0,000 9,581E-03 0,01607508 ! regulation of defense response to virus GO:0050688 35 18 0,000 9,581E-03 0,01606405 ! epidermis morphogenesis GO:0048730 43 18 0,000 9,581E-03 0,01605303 ! glycine metabolic process GO:0006544 30 18 0,000 9,581E-03 0,01604203 ! glutamine metabolic process GO:0006541 29 18 0,000 9,581E-03 0,01603104 ! response to retinoic acid GO:0032526 31 18 0,000 9,581E-03 0,01602007 ! cell-substrate junction assembly GO:0007044 56 18 0,000 9,581E-03 0,01600911 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 9,581E-03 0,01599817 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 9,581E-03 0,01598724 ! DNA integration GO:0015074 32 18 0,000 9,581E-03 0,01597633 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 9,581E-03 0,01596543 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 9,581E-03 0,01595454 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 9,581E-03 0,01594368 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 9,581E-03 0,01593282 ! neural crest cell migration GO:0001755 41 18 0,000 9,581E-03 0,01592198 ! long-chain fatty acid transport GO:0015909 32 18 0,000 9,581E-03 0,01591116 ! sphingolipid catabolic process GO:0030149 32 18 0,000 9,581E-03 0,01590035 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 9,581E-03 0,01588956 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 9,581E-03 0,01587878 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 9,581E-03 0,01586801 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 9,581E-03 0,01585726 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 9,581E-03 0,01584652 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 9,581E-03 0,0158358 ! detection of bacterium GO:0016045 22 18 0,000 9,581E-03 0,0158251 ! nerve development GO:0021675 34 18 0,000 9,581E-03 0,0158144 ! defense response to virus GO:0051607 43 18 0,000 9,581E-03 0,01580373 ! microspike assembly GO:0030035 46 18 0,000 9,581E-03 0,01579306 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 9,581E-03 0,01578241 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 9,581E-03 0,01577178 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,01011026 0,01663257 ! positive regulation of translation GO:0045727 31 19 0,000 0,01011026 0,01662138 ! negative regulation of defense response GO:0031348 27 19 0,000 0,01011026 0,0166102 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,01011026 0,01659903 ! neuron maturation GO:0042551 46 19 0,000 0,01011026 0,01658789 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,01011026 0,01657675 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,01011026 0,01656564 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,01011026 0,01655453 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,01011026 0,01654345 ! inositol metabolic process GO:0006020 33 19 0,000 0,01011026 0,01653237 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01011026 0,01652131 ! memory GO:0007613 34 19 0,000 0,01011026 0,01651027 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,01011026 0,01649924 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,01011026 0,01648823 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,01011026 0,01647723 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,01011026 0,01646624 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,01011026 0,01645527 ! cerebral cortex development GO:0021987 40 19 0,000 0,01011026 0,01644432 ! pigmentation during development GO:0048066 42 19 0,000 0,01011026 0,01643338 ! response to vitamin A GO:0033189 32 19 0,000 0,01011026 0,01642245 ! heme metabolic process GO:0042168 40 19 0,000 0,01011026 0,01641154 ! neuromuscular junction development GO:0007528 43 19 0,000 0,01011026 0,01640064 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,01011026 0,01638976 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,01011026 0,01637889 ! response to fungus GO:0009620 26 19 0,000 0,01011026 0,01636803 ! peptide cross-linking GO:0018149 39 19 0,000 0,01011026 0,01635719 ! protein export from nucleus GO:0006611 40 19 0,000 0,01011026 0,01634637 ! heart process GO:0003015 32 19 0,000 0,01011026 0,01633556 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,01011026 0,01632476 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,01011026 0,01631398 ! cellular pigmentation GO:0033059 37 19 0,000 0,01011026 0,01630321 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,01011026 0,01629246 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,01011026 0,01628172 ! vitamin transport GO:0051180 31 19 0,000 0,01011026 0,01627099 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,01011026 0,01626028 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,01011026 0,01624958 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,01011026 0,0162389 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,01011026 0,01622823 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,01011026 0,01621757 ! cilium assembly GO:0042384 38 19 0,000 0,01011026 0,01620693 ! peptide hormone secretion GO:0030072 32 19 0,000 0,01011026 0,0161963 ! protein secretion GO:0009306 45 20 0,000 0,01063969 0,01703326 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,01063969 0,01702211 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,01063969 0,01701097 ! positive regulation of ossification GO:0045778 50 20 0,000 0,01063969 0,01699984 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,01063969 0,01698873 ! skin development GO:0043588 42 20 0,000 0,01063969 0,01697763 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,01063969 0,01696655 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,01063969 0,01695548 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,01063969 0,01694443 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,01063969 0,01693339 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,01063969 0,01692237 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,01063969 0,01691136 ! response to vitamin GO:0033273 36 20 0,000 0,01063969 0,01690036 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,01063969 0,01688938 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,01063969 0,01687841 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,01063969 0,01686746 ! bile acid metabolic process GO:0008206 34 20 0,000 0,01063969 0,01685652 ! response to alkaloid GO:0043279 38 20 0,000 0,01063969 0,0168456 ! retinoid metabolic process GO:0001523 34 20 0,000 0,01063969 0,01683469 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,01063969 0,01682379 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,01063969 0,01681291 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,01063969 0,01680204 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,01063969 0,01679119 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,01063969 0,01678035 ! actin filament bundle formation GO:0051017 47 20 0,000 0,01063969 0,01676952 ! body fluid secretion GO:0007589 33 20 0,000 0,01063969 0,01675871 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,01063969 0,01674791 ! peptide secretion GO:0002790 38 20 0,000 0,01063969 0,01673712 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,01063969 0,01672635 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,01063969 0,0167156 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,01063969 0,01670486 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,01063969 0,01669413 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,01063969 0,01668341 ! cell-cell junction organization GO:0045216 43 20 0,000 0,01063969 0,01667271 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,01063969 0,01666202 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,01063969 0,01665135 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,01063969 0,01664069 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,01063969 0,01663004 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,01063969 0,01661941 ! regulation of glucose import GO:0046324 30 20 0,000 0,01063969 0,01660879 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,01063969 0,01659818 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,01063969 0,01658759 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,01063969 0,01657701 ! negative regulation of translation GO:0017148 32 20 0,000 0,01063969 0,01656645 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,01063969 0,01655589 ! regulation of cell killing GO:0031341 46 21 0,000 0,01116885 0,01736823 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,01116885 0,01735718 ! hormone secretion GO:0046879 39 21 0,000 0,01116885 0,01734615 ! lipid phosphorylation GO:0046834 43 21 0,000 0,01116885 0,01733513 ! cAMP metabolic process GO:0046058 41 21 0,000 0,01116885 0,01732412 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,01116885 0,01731313 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,01116885 0,01730215 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,01116885 0,01729119 ! ovarian follicle development GO:0001541 39 21 0,000 0,01116885 0,01728023 ! smooth muscle contraction GO:0006939 48 21 0,000 0,01116885 0,0172693 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,01116885 0,01725837 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,01116885 0,01724747 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,01116885 0,01723657 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,01116885 0,01722569 ! plasma membrane fusion GO:0045026 33 21 0,000 0,01116885 0,01721482 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,01116885 0,01720397 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,01116885 0,01719313 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,01116885 0,0171823 ! sensory perception of pain GO:0019233 33 21 0,000 0,01116885 0,01717149 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,01116885 0,01716069 ! diencephalon development GO:0021536 36 21 0,000 0,01116885 0,0171499 ! collagen fibril organization GO:0030199 62 21 0,000 0,01116885 0,01713913 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,01116885 0,01712837 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,01116885 0,01711762 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,01116885 0,01710689 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,01116885 0,01709617 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,01116885 0,01708547 ! collagen catabolic process GO:0030574 29 21 0,000 0,01116885 0,01707478 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,01116885 0,0170641 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,01116885 0,01705343 ! sperm-egg recognition GO:0035036 23 21 0,000 0,01116885 0,01704278 ! actin filament-based movement GO:0030048 47 21 0,000 0,01116885 0,01703214 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,01116885 0,01702152 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,01169774 0,01781644 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,01169774 0,01780534 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,01169774 0,01779425 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,01169774 0,01778318 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,01169774 0,01777212 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,01169774 0,01776108 ! microtubule-based transport GO:0010970 59 22 0,000 0,01169774 0,01775004 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,01169774 0,01773903 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,01169774 0,01772802 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,01169774 0,01771703 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,01169774 0,01770605 ! cellular response to starvation GO:0009267 37 22 0,000 0,01169774 0,01769509 ! vacuolar transport GO:0007034 41 22 0,000 0,01169774 0,01768414 ! central nervous system neuron development GO:0021954 47 22 0,000 0,01169774 0,0176732 ! fucose metabolic process GO:0006004 44 22 0,000 0,01169774 0,01766228 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,01169774 0,01765137 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,01169774 0,01764048 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,01169774 0,01762959 ! ureteric bud development GO:0001657 50 22 0,000 0,01169774 0,01761872 ! stem cell differentiation GO:0048863 57 22 0,000 0,01169774 0,01760787 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,01169774 0,01759703 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,01169774 0,0175862 ! cytolysis GO:0019835 27 22 0,000 0,01169774 0,01757538 ! renal system process GO:0003014 42 22 0,000 0,01169774 0,01756458 ! vasodilation GO:0042311 40 22 0,000 0,01169774 0,01755379 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,01169774 0,01754301 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,01169774 0,01753225 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,01169774 0,0175215 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,01169774 0,01751077 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,01169774 0,01750004 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,01169774 0,01748933 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,01169774 0,01747864 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,01169774 0,01746795 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,01169774 0,01745728 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,01169774 0,01744662 ! sarcomere organization GO:0045214 32 22 0,000 0,01169774 0,01743598 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,01169774 0,01742535 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,01169774 0,01741473 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,01169774 0,01740412 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,01169774 0,01739353 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,01169774 0,01738295 ! gut development GO:0048565 44 22 0,000 0,01169774 0,01737238 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,01169774 0,01736183 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,01169774 0,01735129 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,01169774 0,01734076 ! protein stabilization GO:0050821 41 22 0,000 0,01169774 0,01733024 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,01222636 0,01810242 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,01222636 0,01809146 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,01222636 0,01808051 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,01222636 0,01806957 ! gluconeogenesis GO:0006094 38 23 0,000 0,01222636 0,01805864 ! glycerol metabolic process GO:0006071 40 23 0,000 0,01222636 0,01804773 ! viral genome replication GO:0019079 44 23 0,000 0,01222636 0,01803683 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,01222636 0,01802595 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,01222636 0,01801508 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,01222636 0,01800422 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,01222636 0,01799337 ! regeneration GO:0031099 42 23 0,000 0,01222636 0,01798254 ! axis specification GO:0009798 43 23 0,000 0,01222636 0,01797172 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,01222636 0,01796091 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,01222636 0,01795012 ! response to ethanol GO:0045471 47 23 0,000 0,01222636 0,01793934 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,01222636 0,01792857 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,01222636 0,01791781 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,01222636 0,01790707 ! peroxisome organization GO:0007031 43 23 0,000 0,01222636 0,01789634 ! lysosome organization GO:0007040 47 23 0,000 0,01222636 0,01788563 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,01222636 0,01787492 ! vesicle targeting GO:0006903 49 23 0,000 0,01222636 0,01786423 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,01222636 0,01785355 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,01222636 0,01784289 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,01222636 0,01783224 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,01222636 0,0178216 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,01222636 0,01781097 ! DNA modification GO:0006304 36 23 0,000 0,01222636 0,01780036 ! fatty acid transport GO:0015908 47 23 0,000 0,01222636 0,01778975 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,01222636 0,01777916 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,01222636 0,01776859 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,01222636 0,01775802 ! hormone transport GO:0009914 41 23 0,000 0,01222636 0,01774747 ! cell-cell recognition GO:0009988 28 23 0,000 0,01222636 0,01773693 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,01222636 0,01772641 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,01222636 0,01771589 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,01222636 0,01770539 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,01275471 0,01845958 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,01275471 0,01844865 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,01275471 0,01843773 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,01275471 0,01842683 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,01275471 0,01841594 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,01275471 0,01840506 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,01275471 0,0183942 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,01275471 0,01838334 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,01275471 0,0183725 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,01275471 0,01836168 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,01275471 0,01835086 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,01275471 0,01834006 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,01275471 0,01832928 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,01275471 0,0183185 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,01275471 0,01830774 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,01275471 0,01829699 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,01275471 0,01828625 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,01275471 0,01827552 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,01275471 0,01826481 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,01275471 0,01825411 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,01275471 0,01824342 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,01275471 0,01823275 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,01275471 0,01822209 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,01275471 0,01821144 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,01275471 0,0182008 ! membrane depolarization GO:0051899 45 24 0,000 0,01275471 0,01819017 ! pallium development GO:0021543 56 24 0,000 0,01275471 0,01817956 ! oogenesis GO:0048477 44 24 0,000 0,01275471 0,01816896 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,01275471 0,01815837 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,01275471 0,0181478 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,01275471 0,01813723 ! platelet activation GO:0030168 41 24 0,000 0,01275471 0,01812668 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,01275471 0,01811614 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,01275471 0,01810562 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,01275471 0,0180951 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,01275471 0,0180846 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,01275471 0,01807411 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,01275471 0,01806363 ! regulation of amine transport GO:0051952 41 24 0,000 0,01275471 0,01805317 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,01275471 0,01804271 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,0132828 0,01877887 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,0132828 0,01876801 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,0132828 0,01875716 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,0132828 0,01874632 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,0132828 0,0187355 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0132828 0,01872469 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0132828 0,01871389 ! phototransduction GO:0007602 37 25 0,000 0,0132828 0,0187031 ! keratinization GO:0031424 37 25 0,000 0,0132828 0,01869233 ! vasculogenesis GO:0001570 49 25 0,000 0,0132828 0,01868157 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,0132828 0,01867082 ! vacuole organization GO:0007033 49 25 0,000 0,0132828 0,01866008 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0132828 0,01864936 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,0132828 0,01863865 ! receptor metabolic process GO:0043112 53 25 0,000 0,0132828 0,01862795 ! chromosome condensation GO:0030261 48 25 0,000 0,0132828 0,01861726 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,0132828 0,01860659 ! regulation of behavior GO:0050795 48 25 0,000 0,0132828 0,01859592 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0132828 0,01858527 ! interaction with host GO:0051701 66 25 0,000 0,0132828 0,01857463 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,0132828 0,01856401 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,0132828 0,01855339 ! immunoglobulin production GO:0002377 62 25 0,000 0,0132828 0,01854279 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0132828 0,0185322 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,0132828 0,01852162 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0132828 0,01851106 ! liver development GO:0001889 55 25 0,000 0,0132828 0,0185005 ! protein tetramerization GO:0051262 57 25 0,000 0,0132828 0,01848996 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,01381062 0,01921375 ! myelination GO:0042552 50 26 0,000 0,01381062 0,01920282 ! initiation of viral infection GO:0019059 60 26 0,000 0,01381062 0,01919189 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,01381062 0,01918098 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,01381062 0,01917008 ! molting cycle process GO:0022404 52 26 0,000 0,01381062 0,0191592 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,01381062 0,01914833 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,01381062 0,01913746 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,01381062 0,01912661 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,01381062 0,01911578 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,01381062 0,01910495 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,01381062 0,01909414 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,01381062 0,01908334 ! digestive system process GO:0022600 49 26 0,000 0,01381062 0,01907255 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,01381062 0,01906178 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,01381062 0,01905102 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,01381062 0,01904026 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,01381062 0,01902953 ! osteoblast differentiation GO:0001649 63 26 0,000 0,01381062 0,0190188 ! neural crest cell development GO:0014032 59 26 0,000 0,01381062 0,01900808 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,01381062 0,01899738 ! negative regulation of cell development GO:0010721 83 26 0,000 0,01381062 0,01898669 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,01381062 0,01897601 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,01381062 0,01896535 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,01381062 0,01895469 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,01381062 0,01894405 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,01381062 0,01893342 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,01381062 0,0189228 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,01381062 0,01891219 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,01381062 0,0189016 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,01381062 0,01889101 ! blastocyst development GO:0001824 50 26 0,000 0,01381062 0,01888044 ! telomere organization GO:0032200 46 26 0,000 0,01381062 0,01886988 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,01381062 0,01885933 ! neural tube closure GO:0001843 58 26 0,000 0,01381062 0,0188488 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,01381062 0,01883827 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,01381062 0,01882776 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,01381062 0,01881726 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,01433817 0,01952517 ! embryonic pattern specification GO:0009880 49 27 0,000 0,01433817 0,01951429 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,01433817 0,01950343 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,01433817 0,01949258 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,01433817 0,01948173 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,01433817 0,01947091 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,01433817 0,01946009 ! iron ion transport GO:0006826 65 27 0,000 0,01433817 0,01944928 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,01433817 0,01943849 ! superoxide metabolic process GO:0006801 41 27 0,000 0,01433817 0,01942771 ! tube lumen formation GO:0035148 59 27 0,000 0,01433817 0,01941694 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,01433817 0,01940618 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,01433817 0,01939544 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,01433817 0,0193847 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,01433817 0,01937398 ! response to starvation GO:0042594 47 27 0,000 0,01433817 0,01936327 ! response to toxin GO:0009636 49 27 0,000 0,01433817 0,01935257 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,01433817 0,01934189 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,01433817 0,01933121 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,01433817 0,01932055 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,01433817 0,0193099 ! leukocyte proliferation GO:0070661 59 27 0,000 0,01433817 0,01929926 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,01433817 0,01928863 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,01486546 0,01998697 ! neuron fate commitment GO:0048663 52 28 0,000 0,01486546 0,01997597 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,01486546 0,01996499 ! protein amino acid acylation GO:0043543 59 28 0,000 0,01486546 0,01995402 ! vesicle docking GO:0048278 55 28 0,000 0,01486546 0,01994306 ! circadian rhythm GO:0007623 56 28 0,000 0,01486546 0,01993212 ! dendrite development GO:0016358 67 28 0,000 0,01486546 0,01992118 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,01486546 0,01991026 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,01486546 0,01989935 ! sperm motility GO:0030317 37 28 0,000 0,01486546 0,01988845 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,01486546 0,01987757 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,01486546 0,01986669 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,01486546 0,01985583 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,01486546 0,01984498 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,01486546 0,01983414 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,01486546 0,01982332 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,01486546 0,0198125 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,01486546 0,0198017 ! glutathione metabolic process GO:0006749 42 28 0,000 0,01486546 0,01979091 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,01486546 0,01978013 ! lipid oxidation GO:0034440 48 28 0,000 0,01486546 0,01976936 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,01486546 0,0197586 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,01486546 0,01974786 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,01539248 0,02043686 ! translational initiation GO:0006413 66 29 0,000 0,01539248 0,02042576 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,01539248 0,02041467 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,01539248 0,02040359 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,01539248 0,02039253 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,01539248 0,02038147 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,01539248 0,02037043 ! primary neural tube formation GO:0014020 61 29 0,000 0,01539248 0,0203594 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,01539248 0,02034839 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,01539248 0,02033738 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,01539248 0,02032639 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,01539248 0,02031541 ! somitogenesis GO:0001756 52 29 0,000 0,01539248 0,02030444 ! synaptogenesis GO:0007416 46 29 0,000 0,01539248 0,02029348 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,01539248 0,02028253 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,01539248 0,0202716 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,01539248 0,02026068 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,01591923 0,02094274 ! phenol metabolic process GO:0018958 56 30 0,000 0,01591923 0,02093147 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,01591923 0,02092021 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,01591923 0,02090896 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,01591923 0,02089773 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,01591923 0,0208865 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,01591923 0,02087529 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,01591923 0,02086409 ! acute-phase response GO:0006953 50 30 0,000 0,01591923 0,02085291 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,01591923 0,02084173 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,01591923 0,02083057 ! myofibril assembly GO:0030239 50 30 0,000 0,01591923 0,02081942 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,01591923 0,02080828 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,01591923 0,02079715 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,01591923 0,02078603 ! cell fate determination GO:0001709 64 30 0,000 0,01591923 0,02077493 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,01591923 0,02076384 ! phospholipid transport GO:0015914 65 30 0,000 0,01591923 0,02075276 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,01591923 0,02074169 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,01591923 0,02073063 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,01591923 0,02071959 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,01591923 0,02070856 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,01591923 0,02069754 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,01591923 0,02068653 ! regulation of coagulation GO:0050818 52 30 0,000 0,01591923 0,02067553 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,01644571 0,02134796 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,01644571 0,02133663 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,01644571 0,0213253 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,01644571 0,02131399 ! cell junction assembly GO:0034329 85 31 0,000 0,01644571 0,02130269 ! regulation of innate immune response GO:0045088 57 31 0,000 0,01644571 0,0212914 ! ovulation cycle process GO:0022602 55 31 0,000 0,01644571 0,02128012 ! peptide transport GO:0015833 60 31 0,000 0,01644571 0,02126886 ! male gonad development GO:0008584 56 31 0,000 0,01644571 0,0212576 ! iron ion homeostasis GO:0055072 60 31 0,000 0,01644571 0,02124636 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,01644571 0,02123513 ! detection of light stimulus GO:0009583 44 31 0,000 0,01644571 0,02122391 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,01644571 0,02121271 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,01644571 0,02120151 ! natural killer cell activation GO:0030101 50 31 0,000 0,01644571 0,02119033 ! ensheathment of neurons GO:0007272 64 31 0,000 0,01644571 0,02117916 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,01644571 0,021168 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,01644571 0,02115686 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,01644571 0,02114572 ! eye morphogenesis GO:0048592 65 31 0,000 0,01644571 0,0211346 ! response to heat GO:0009408 54 31 0,000 0,01644571 0,02112349 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,01644571 0,02111239 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,01697193 0,02177648 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,01697193 0,02176505 ! collagen metabolic process GO:0032963 49 32 0,000 0,01697193 0,02175363 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,01697193 0,02174222 ! spindle organization GO:0007051 50 32 0,000 0,01697193 0,02173083 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,01697193 0,02171944 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,01697193 0,02170807 ! metanephros development GO:0001656 81 32 0,000 0,01697193 0,02169671 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,01697193 0,02168536 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,01697193 0,02167403 ! muscle cell development GO:0055001 52 32 0,000 0,01697193 0,0216627 ! mesoderm formation GO:0001707 73 32 0,000 0,01697193 0,02165139 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,01697193 0,02164009 ! ovulation cycle GO:0042698 57 32 0,000 0,01697193 0,0216288 ! peripheral nervous system development GO:0007422 68 32 0,000 0,01697193 0,02161753 ! BMP signaling pathway GO:0030509 71 32 0,000 0,01697193 0,02160626 ! hindbrain development GO:0030902 65 32 0,000 0,01697193 0,02159501 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,01697193 0,02158377 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,01697193 0,02157254 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,01697193 0,02156132 ! gene silencing GO:0016458 71 32 0,000 0,01697193 0,02155011 ! regulation of pH GO:0006885 56 33 0,000 0,01749788 0,0222064 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,01749788 0,02219487 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,01749788 0,02218335 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,01749788 0,02217184 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,01749788 0,02216035 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,01749788 0,02214887 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,01749788 0,0221374 ! response to ionizing radiation GO:0010212 74 33 0,000 0,01749788 0,02212594 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,01749788 0,02211449 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,01749788 0,02210306 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,01749788 0,02209163 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,01749788 0,02208022 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,01749788 0,02206882 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,01749788 0,02205744 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,01749788 0,02204606 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,01802356 0,02269668 ! glial cell differentiation GO:0010001 67 34 0,000 0,01802356 0,02268499 ! post-embryonic development GO:0009791 76 34 0,000 0,01802356 0,0226733 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,01802356 0,02266164 ! cholesterol transport GO:0030301 62 34 0,000 0,01802356 0,02264998 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,01802356 0,02263833 ! spliceosome assembly GO:0000245 75 34 0,000 0,01802356 0,0226267 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,01802356 0,02261508 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,01802356 0,02260347 ! formation of primary germ layer GO:0001704 76 34 0,000 0,01802356 0,02259187 ! cell fate specification GO:0001708 56 34 0,000 0,01802356 0,02258029 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,01802356 0,02256871 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,01802356 0,02255715 ! adult locomotory behavior GO:0008344 62 34 0,000 0,01802356 0,0225456 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,01802356 0,02253406 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,01854898 0,02317911 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,01854898 0,02316725 ! negative regulation of secretion GO:0051048 68 35 0,000 0,01854898 0,02315542 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,01854898 0,02314359 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,01854898 0,02313178 ! membrane docking GO:0022406 69 35 0,000 0,01854898 0,02311997 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,01854898 0,02310818 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,01854898 0,02309641 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,01854898 0,02308464 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,01854898 0,02307289 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,01854898 0,02306115 ! ceramide metabolic process GO:0006672 72 35 0,000 0,01854898 0,02304942 ! telencephalon development GO:0021537 81 35 0,000 0,01854898 0,0230377 ! sterol transport GO:0015918 63 35 0,000 0,01854898 0,02302599 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,01854898 0,0230143 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,01854898 0,02300261 ! placenta development GO:0001890 53 35 0,000 0,01854898 0,02299094 ! vesicle localization GO:0051648 70 35 0,000 0,01854898 0,02297929 ! regulation of muscle development GO:0048634 82 36 0,000 0,01907413 0,02361789 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,01907413 0,02360592 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,01907413 0,02359397 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,01907413 0,02358203 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,01907413 0,0235701 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,01907413 0,02355819 ! positive regulation of cell development GO:0010720 85 36 0,000 0,01907413 0,02354628 ! protein targeting to membrane GO:0006612 75 36 0,000 0,01907413 0,02353439 ! regulation of proteolysis GO:0030162 77 36 0,000 0,01907413 0,02352251 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,01907413 0,02351064 ! aerobic respiration GO:0009060 56 36 0,000 0,01907413 0,02349879 ! cytokine production GO:0001816 68 36 0,000 0,01907413 0,02348694 ! embryonic organ development GO:0048568 67 36 0,000 0,01907413 0,02347511 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,01907413 0,02346329 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,01907413 0,02345148 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,01959901 0,0240847 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,01959901 0,02407259 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,01959901 0,0240605 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,01959901 0,02404841 ! sister chromatid segregation GO:0000819 65 37 0,000 0,01959901 0,02403634 ! odontogenesis GO:0042476 74 37 0,000 0,01959901 0,02402428 ! actomyosin structure organization GO:0031032 68 37 0,000 0,01959901 0,02401223 ! cell junction organization GO:0034330 96 37 0,000 0,01959901 0,02400019 ! tissue remodeling GO:0048771 78 37 0,000 0,01959901 0,02398817 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,01959901 0,02397616 ! female gonad development GO:0008585 71 37 0,000 0,01959901 0,02396416 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,01959901 0,02395217 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,01959901 0,02394019 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,01959901 0,02392823 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,01959901 0,02391628 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,02012363 0,0245442 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,02012363 0,02453195 ! meiosis I GO:0007127 74 38 0,000 0,02012363 0,02451971 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,02012363 0,02450749 ! organic anion transport GO:0015711 82 38 0,000 0,02012363 0,02449528 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,02012363 0,02448308 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,02012363 0,02447089 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,02012363 0,02445872 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,02012363 0,02444656 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,02012363 0,02443441 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,02012363 0,02442227 ! regulation of protein stability GO:0031647 77 38 0,000 0,02012363 0,02441014 ! spermatid development GO:0007286 69 38 0,000 0,02012363 0,02439803 ! glycogen metabolic process GO:0005977 63 38 0,000 0,02012363 0,02438593 ! pigment metabolic process GO:0042440 87 38 0,000 0,02012363 0,02437384 ! neural tube formation GO:0001841 79 38 0,000 0,02012363 0,02436176 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,02064798 0,02498416 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,02064798 0,02497179 ! negative regulation of binding GO:0051100 71 39 0,000 0,02064798 0,02495944 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,02064798 0,02494709 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,02064798 0,02493476 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,02064798 0,02492244 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,02064798 0,02491013 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,02064798 0,02489784 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,02064798 0,02488556 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,02064798 0,02487328 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,02064798 0,02486103 ! glucan metabolic process GO:0044042 64 39 0,000 0,02064798 0,02484878 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,02117207 0,02546694 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,02117207 0,02545441 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,02117207 0,02544189 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,02117207 0,02542938 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,02117207 0,02541689 ! lipid homeostasis GO:0055088 75 40 0,000 0,02117207 0,0254044 ! mismatch repair GO:0006298 58 40 0,000 0,02117207 0,02539193 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,02117207 0,02537947 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,02117207 0,02536702 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,02117207 0,02535459 ! RNA export from nucleus GO:0006405 61 41 0,000 0,02169589 0,02596916 ! mRNA catabolic process GO:0006402 79 41 0,000 0,02169589 0,02595644 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,02169589 0,02594374 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,02169589 0,02593105 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,02169589 0,02591837 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,02169589 0,0259057 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,02169589 0,02589304 ! gliogenesis GO:0042063 91 41 0,000 0,02169589 0,0258804 ! feeding behavior GO:0007631 69 41 0,000 0,02169589 0,02586777 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,02169589 0,02585515 ! mesenchymal cell development GO:0014031 94 41 0,000 0,02169589 0,02584254 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,02169589 0,02582995 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,02169589 0,02581737 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,02169589 0,0258048 ! spermatid differentiation GO:0048515 73 41 0,000 0,02169589 0,02579224 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,02169589 0,0257797 ! RNA modification GO:0009451 64 41 0,000 0,02169589 0,02576716 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,02221944 0,02637614 ! ear morphogenesis GO:0042471 64 42 0,000 0,02221944 0,02636333 ! organic ether metabolic process GO:0018904 59 42 0,000 0,02221944 0,02635054 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,02221944 0,02633775 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,02221944 0,02632498 ! T cell differentiation GO:0030217 93 42 0,000 0,02221944 0,02631222 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,02221944 0,02629947 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,02221944 0,02628673 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,02221944 0,02627401 ! regulation of protein secretion GO:0050708 77 42 0,000 0,02221944 0,0262613 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,02221944 0,0262486 ! cytokinesis GO:0000910 84 42 0,000 0,02221944 0,02623591 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,02221944 0,02622324 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,02274273 0,02682786 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,02274273 0,02681491 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,02274273 0,02680198 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,02274273 0,02678905 ! regulation of tube size GO:0035150 76 43 0,000 0,02274273 0,02677614 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,02274273 0,02676325 ! glucose transport GO:0015758 66 43 0,000 0,02274273 0,02675036 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,02274273 0,02673749 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,02274273 0,02672463 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,02274273 0,02671178 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,02274273 0,02669894 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,02274273 0,02668612 ! segmentation GO:0035282 78 43 0,000 0,02274273 0,02667331 ! ion transmembrane transport GO:0034220 79 43 0,000 0,02274273 0,02666051 ! neuron migration GO:0001764 85 43 0,000 0,02274273 0,02664772 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,02274273 0,02663495 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,02326576 0,02723443 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,02326576 0,02722138 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,02326576 0,02720835 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,02326576 0,02719533 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,02326576 0,02718233 ! hexose transport GO:0008645 68 44 0,000 0,02326576 0,02716933 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,02326576 0,02715635 ! striated muscle contraction GO:0006941 85 44 0,000 0,02326576 0,02714338 ! phagocytosis GO:0006909 105 44 0,000 0,02326576 0,02713043 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,02326576 0,02711748 ! double-strand break repair GO:0006302 85 44 0,000 0,02326576 0,02710455 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,02378852 0,02770036 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,02378852 0,02768716 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,02378852 0,02767398 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,02378852 0,0276608 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,02378852 0,02764764 ! biopolymer methylation GO:0043414 91 45 0,000 0,02378852 0,0276345 ! B cell differentiation GO:0030183 124 45 0,000 0,02378852 0,02762136 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,02378852 0,02760824 ! female gamete generation GO:0007292 71 45 0,000 0,02378852 0,02759513 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,02378852 0,02758204 ! polyol metabolic process GO:0019751 77 45 0,000 0,02378852 0,02756895 ! developmental growth GO:0048589 88 45 0,000 0,02378852 0,02755588 ! maintenance of location in cell GO:0051651 101 45 0,000 0,02378852 0,02754282 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,02431101 0,02813444 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,02431101 0,02812112 ! glycolysis GO:0006096 71 46 0,000 0,02431101 0,02810781 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,02431101 0,02809451 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,02431101 0,02808123 ! leukocyte migration GO:0050900 75 46 0,000 0,02431101 0,02806796 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,02431101 0,0280547 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,02431101 0,02804146 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,02431101 0,02802822 ! pigmentation GO:0043473 103 46 0,000 0,02431101 0,028015 ! cell growth GO:0016049 90 46 0,000 0,02431101 0,02800179 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,02431101 0,0279886 ! neural tube development GO:0021915 91 47 0,000 0,02483324 0,02857636 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,02483324 0,0285629 ! positive regulation of defense response GO:0031349 88 48 0,000 0,02535521 0,02914954 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,02535521 0,02913583 ! mitochondrial transport GO:0006839 94 48 0,000 0,02535521 0,02912213 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,02535521 0,02910844 ! cellular component disassembly GO:0022411 89 48 0,000 0,02535521 0,02909477 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,02535521 0,02908111 ! endosome transport GO:0016197 127 48 0,000 0,02535521 0,02906746 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,02535521 0,02905383 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,02535521 0,02904021 ! male sex differentiation GO:0046661 93 48 0,000 0,02535521 0,0290266 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,02535521 0,02901301 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,02535521 0,02899942 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,02535521 0,02898585 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,02535521 0,02897229 ! methylation GO:0032259 97 48 0,000 0,02535521 0,02895875 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,0258769 0,02954078 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,0258769 0,02952699 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,0258769 0,0295132 ! JNK cascade GO:0007254 106 49 0,000 0,0258769 0,02949943 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,0258769 0,02948567 ! protein homooligomerization GO:0051260 84 49 0,000 0,0258769 0,02947192 ! regulation of action potential GO:0001508 102 50 0,000 0,02639834 0,03005179 ! regulation of ion transport GO:0043269 86 50 0,000 0,02639834 0,03003779 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,02639834 0,03002381 ! endocrine system development GO:0035270 109 50 0,000 0,02639834 0,03000984 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,02639834 0,02999588 ! activation of caspase activity GO:0006919 95 50 0,000 0,02639834 0,02998194 ! regulation of ossification GO:0030278 123 50 0,000 0,02639834 0,029968 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,02639834 0,02995408 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,02639834 0,02994018 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,02639834 0,02992629 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,02639834 0,0299124 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,02639834 0,02989854 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,02691951 0,03047468 ! viral infectious cycle GO:0019058 104 51 0,000 0,02691951 0,03046057 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,02691951 0,03044647 ! peptide metabolic process GO:0006518 80 51 0,000 0,02691951 0,03043238 ! response to temperature stimulus GO:0009266 84 51 0,000 0,02691951 0,0304183 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,02691951 0,03040424 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,02691951 0,03039019 ! positive regulation of binding GO:0051099 88 52 0,000 0,02744042 0,03096394 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,02744042 0,03094965 ! Notch signaling pathway GO:0007219 111 52 0,000 0,02744042 0,03093537 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,02744042 0,0309211 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,02744042 0,03090684 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,02744042 0,0308926 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,02744042 0,03087837 ! excretion GO:0007588 87 52 0,000 0,02744042 0,03086415 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,02744042 0,03084995 ! histone modification GO:0016570 104 52 0,000 0,02744042 0,03083576 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,02744042 0,03082158 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,02744042 0,03080742 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,02744042 0,03079327 ! amino acid activation GO:0043038 98 52 0,000 0,02744042 0,03077913 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,02796106 0,03134872 ! positive regulation of growth GO:0045927 96 53 0,000 0,02796106 0,03133434 ! inner ear development GO:0048839 89 53 0,000 0,02796106 0,03131998 ! chromatin remodeling GO:0006338 122 53 0,000 0,02796106 0,03130562 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,02796106 0,03129128 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,02796106 0,03127695 ! vesicle organization GO:0016050 127 53 0,000 0,02796106 0,03126264 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,02796106 0,03124834 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 0,000 0,02796106 0,03123405 ! synapse organization GO:0050808 102 53 0,000 0,02796106 0,03121978 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,02848144 0,03178627 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,02848144 0,03177176 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,02848144 0,03175726 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,02848144 0,03174277 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,02848144 0,0317283 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,02848144 0,03171383 ! membrane fusion GO:0006944 122 54 0,000 0,02848144 0,03169939 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,02848144 0,03168495 ! covalent chromatin modification GO:0016569 115 54 0,000 0,02848144 0,03167053 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,02848144 0,03165612 ! regulation of cell shape GO:0008360 142 54 0,000 0,02848144 0,03164172 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,02848144 0,03162734 ! RNA catabolic process GO:0006401 103 55 0,000 0,02900155 0,03219027 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,02900155 0,03217565 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,02900155 0,03216105 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,02900155 0,03214646 ! cell recognition GO:0008037 98 55 0,000 0,02900155 0,03213188 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,02900155 0,03211731 ! cell maturation GO:0048469 107 55 0,000 0,02900155 0,03210276 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,02900155 0,03208822 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,02900155 0,03207369 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,0295214 0,03263384 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,0295214 0,03261908 ! glucose catabolic process GO:0006007 88 56 0,000 0,0295214 0,03260433 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,0295214 0,0325896 ! RNA elongation GO:0006354 90 56 0,000 0,0295214 0,03257488 ! chloride transport GO:0006821 102 57 0,000 0,03004099 0,03313324 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,03004099 0,03311829 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,03004099 0,03310335 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,03004099 0,03308843 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,03004099 0,03307352 ! heart morphogenesis GO:0003007 105 57 0,000 0,03004099 0,03305862 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,03004099 0,03304373 ! regulation of actin filament length GO:0030832 118 58 0,000 0,03056031 0,03359984 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,03056031 0,03358472 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,03056031 0,03356962 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,03056031 0,03355454 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,03056031 0,03353946 ! gastrulation GO:0007369 122 58 0,000 0,03056031 0,0335244 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,03056031 0,03350935 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,03056031 0,03349432 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,03056031 0,0334793 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,03056031 0,03346429 ! maintenance of location GO:0051235 124 58 0,000 0,03056031 0,0334493 ! nuclear export GO:0051168 110 59 0,000 0,03107937 0,0340022 ! establishment of organelle localization GO:0051656 122 59 0,000 0,03107937 0,03398698 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,03159817 0,03453885 ! lipid modification GO:0030258 112 60 0,000 0,03159817 0,0345234 ! DNA catabolic process GO:0006308 94 60 0,000 0,03159817 0,03450797 ! regulation of endocytosis GO:0030100 104 60 0,000 0,03159817 0,03449255 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,03159817 0,03447714 ! adult behavior GO:0030534 104 60 0,000 0,03159817 0,03446175 ! kidney development GO:0001822 133 60 0,000 0,03159817 0,03444637 ! positive regulation of secretion GO:0051047 110 61 0,000 0,0321167 0,03499603 ! regulation of cellular component size GO:0032535 125 61 0,000 0,0321167 0,03498043 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,0321167 0,03496484 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,0321167 0,03494927 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,0321167 0,0349337 ! regulation of heart contraction GO:0008016 123 61 0,000 0,0321167 0,03491816 ! camera-type eye development GO:0043010 126 61 0,000 0,0321167 0,03490263 ! proton transport GO:0015992 117 61 0,000 0,0321167 0,03488711 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,0321167 0,0348716 ! viral reproductive process GO:0022415 132 62 0,000 0,03263497 0,03541859 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,03263497 0,03540286 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,03263497 0,03538714 ! tRNA processing GO:0008033 102 62 0,000 0,03263497 0,03537144 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,03263497 0,03535576 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,03315298 0,03590103 ! regulation of mitosis GO:0007088 112 63 0,000 0,03315298 0,03588513 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,03315298 0,03586923 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,03315298 0,03585335 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,03315298 0,03583749 ! hydrogen transport GO:0006818 121 64 0,000 0,03367072 0,03638106 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,03367072 0,03636498 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,03367072 0,03634891 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,03367072 0,03633285 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,03418821 0,03687496 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,03418821 0,03685869 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,03418821 0,03684243 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,03418821 0,03682618 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,03418821 0,03680995 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,03418821 0,03679374 ! ear development GO:0043583 114 66 0,000 0,03470542 0,03733393 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,03470542 0,0373175 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,03470542 0,03730108 ! gonad development GO:0008406 115 66 0,000 0,03470542 0,03728468 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,03470542 0,03726829 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,03522238 0,0378068 ! activation of MAPK activity GO:0000187 124 67 0,000 0,03522238 0,0377902 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,03522238 0,03777361 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,03522238 0,03775703 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,03522238 0,03774047 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,03522238 0,03772393 ! secondary metabolic process GO:0019748 125 67 0,000 0,03522238 0,0377074 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,03522238 0,03769088 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,03573908 0,03822704 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,03573908 0,03821031 ! hexose catabolic process GO:0019320 113 68 0,000 0,03573908 0,0381936 ! extracellular matrix organization GO:0030198 146 68 0,000 0,03573908 0,0381769 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,03573908 0,03816021 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,03573908 0,03814354 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,03573908 0,03812688 ! viral reproduction GO:0016032 142 68 0,000 0,03573908 0,03811024 ! regulation of lipase activity GO:0060191 137 68 0,000 0,03573908 0,03809361 ! adaptive immune response GO:0002250 126 68 0,000 0,03573908 0,038077 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,03573908 0,0380604 ! negative regulation of cell size GO:0045792 144 69 0,000 0,03625551 0,03859355 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,03625551 0,03857675 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,03625551 0,03855995 ! lung development GO:0030324 165 69 0,000 0,03625551 0,03854317 ! urogenital system development GO:0001655 149 69 0,000 0,03625551 0,03852641 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,03625551 0,03850966 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,03625551 0,03849292 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,03625551 0,0384762 ! developmental maturation GO:0021700 128 69 0,000 0,03625551 0,03845949 ! single fertilization GO:0007338 83 69 0,000 0,03625551 0,0384428 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,03677168 0,03897319 ! cell redox homeostasis GO:0045454 114 70 0,000 0,03677168 0,03895629 ! germ cell development GO:0007281 133 70 0,000 0,03677168 0,03893941 ! activation of immune response GO:0002253 120 70 0,000 0,03677168 0,03892254 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,03677168 0,03890568 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,03728759 0,03943445 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,03728759 0,03941738 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,03728759 0,03940034 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,03728759 0,0393833 ! appendage morphogenesis GO:0035107 150 72 0,000 0,03780323 0,03991067 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,03780323 0,03989343 ! respiratory tube development GO:0030323 171 72 0,000 0,03780323 0,03987621 ! actin filament organization GO:0007015 167 72 0,000 0,03780323 0,039859 ! B cell activation GO:0042113 179 72 0,000 0,03780323 0,0398418 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,03780323 0,03982462 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,03780323 0,03980746 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,03780323 0,03979031 ! appendage development GO:0048736 151 73 0,000 0,03831862 0,04031541 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,03831862 0,04029806 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,03831862 0,04028072 ! regulation of immune effector process GO:0002697 156 73 0,000 0,03831862 0,04026339 ! acute inflammatory response GO:0002526 118 74 0,000 0,03883374 0,04078712 ! amino acid transport GO:0006865 148 74 0,000 0,03883374 0,04076959 ! regulation of caspase activity GO:0043281 136 74 0,000 0,03883374 0,04075208 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,03883374 0,04073458 ! respiratory system development GO:0060541 175 74 0,000 0,03883374 0,0407171 ! organelle localization GO:0051640 155 74 0,000 0,03883374 0,04069963 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,0393486 0,04122154 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,0393486 0,04120388 ! reproductive structure development GO:0048608 131 75 0,000 0,0393486 0,04118622 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,0393486 0,04116858 ! eye development GO:0001654 155 75 0,000 0,0393486 0,04115096 ! axon guidance GO:0007411 162 75 0,000 0,0393486 0,04113335 ! rhythmic process GO:0048511 142 75 0,000 0,0393486 0,04111576 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,03986321 0,04163566 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,03986321 0,04161787 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,03986321 0,04160009 ! regulation of blood pressure GO:0008217 134 76 0,000 0,03986321 0,04158233 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,03986321 0,04156458 ! amine catabolic process GO:0009310 136 77 0,000 0,04037755 0,04208291 ! neurotransmitter transport GO:0006836 142 77 0,000 0,04037755 0,04206497 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,04037755 0,04204703 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,04037755 0,04202912 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,04037755 0,04201122 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,04037755 0,04199333 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,04037755 0,04197547 ! regulation of catabolic process GO:0009894 173 77 0,000 0,04037755 0,04195761 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,04089162 0,04247374 ! antigen processing and presentation GO:0019882 117 78 0,000 0,04089162 0,04245569 ! fertilization GO:0009566 99 78 0,000 0,04089162 0,04243765 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,04089162 0,04241963 ! blood coagulation GO:0007596 151 79 0,000 0,04140544 0,04293442 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,04140544 0,0429162 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,04140544 0,042898 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,04140544 0,04287982 ! protein oligomerization GO:0051259 149 79 0,000 0,04140544 0,04286165 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,041919 0,04337489 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,041919 0,04335653 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,041919 0,04333818 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,041919 0,04331984 ! meiosis GO:0007126 143 81 0,000 0,04243229 0,04383175 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 0,000 0,04243229 0,04381323 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,04243229 0,04379472 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,04294533 0,04430551 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,04294533 0,04428681 ! protein import into nucleus GO:0006606 174 82 0,000 0,04294533 0,04426812 ! meiotic cell cycle GO:0051321 144 82 0,000 0,04294533 0,04424945 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,04345811 0,04475892 ! exocytosis GO:0006887 153 83 0,000 0,04345811 0,04474006 ! response to drug GO:0042493 149 83 0,000 0,04345811 0,04472121 ! response to oxygen levels GO:0070482 183 83 0,000 0,04345811 0,04470238 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,04345811 0,04468357 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,04345811 0,04466477 ! nuclear import GO:0051170 177 83 0,000 0,04345811 0,04464599 ! inorganic anion transport GO:0015698 156 83 0,000 0,04345811 0,04462722 ! T cell activation GO:0042110 189 84 0,000 0,04397062 0,04513455 ! response to nutrient GO:0007584 135 84 0,000 0,04397062 0,04511559 ! digestion GO:0007586 130 84 0,000 0,04397062 0,04509665 ! hemostasis GO:0007599 165 85 0,000 0,04448288 0,04560288 ! negative regulation of transport GO:0051051 164 85 0,000 0,04448288 0,04558375 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,04448288 0,04556464 ! negative regulation of growth GO:0045926 168 85 0,000 0,04448288 0,04554554 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,04448288 0,04552646 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,04448288 0,0455074 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,04499487 0,04601192 ! regulation of lyase activity GO:0051339 169 86 0,000 0,04499487 0,04599266 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,04499487 0,04597343 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,04550661 0,04647686 ! mitochondrion organization GO:0007005 159 87 0,000 0,04550661 0,04645743 ! alcohol catabolic process GO:0046164 142 87 0,000 0,04550661 0,04643803 ! nucleosome assembly GO:0006334 126 87 0,000 0,04550661 0,04641864 ! regulation of protein transport GO:0051223 165 87 0,000 0,04550661 0,04639926 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,04601808 0,0469012 ! amine biosynthetic process GO:0009309 146 88 0,000 0,04601808 0,04688164 ! sensory perception of smell GO:0007608 117 88 0,000 0,04601808 0,0468621 ! chromatin assembly GO:0031497 128 88 0,000 0,04601808 0,04684257 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,04601808 0,04682306 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,0465293 0,04732351 ! regulation of DNA binding GO:0051101 167 89 0,000 0,0465293 0,04730382 ! tube morphogenesis GO:0035239 194 89 0,000 0,0465293 0,04728414 ! cellular defense response GO:0006968 123 89 0,000 0,0465293 0,04726448 ! protein localization in nucleus GO:0034504 192 89 0,000 0,0465293 0,04724483 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,04704025 0,0477438 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,04704025 0,04772398 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,04755095 0,04822207 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,04755095 0,04820206 ! gland development GO:0048732 220 91 0,000 0,04755095 0,04818207 ! defense response to bacterium GO:0042742 112 91 0,000 0,04755095 0,04816209 ! bone development GO:0060348 206 92 0,000 0,04806139 0,04865892 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,04806139 0,04863876 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,04806139 0,04861862 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,04857156 0,04911438 ! amine transport GO:0015837 181 93 0,000 0,04857156 0,04909406 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,04857156 0,04907375 ! vitamin metabolic process GO:0006766 153 93 0,000 0,04857156 0,04905346 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,04908148 0,04954796 ! female pregnancy GO:0007565 166 94 0,000 0,04908148 0,04952749 ! sterol metabolic process GO:0016125 166 94 0,000 0,04908148 0,04950705 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,04908148 0,04948661 ! regulation of membrane potential GO:0042391 179 94 0,000 0,04908148 0,0494662 ! regulation of defense response GO:0031347 171 95 0,000 0,04959114 0,04995924 ! nucleosome organization GO:0034728 143 95 0,000 0,04959114 0,04993865 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,04959114 0,04991807 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,04959114 0,04989751 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,04959114 0,04987697 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,04959114 0,04985645 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,04959114 0,04983594 ! sex differentiation GO:0007548 171 96 0,000 0,05010054 0,05032715 ! regulation of T cell activation GO:0050863 175 96 0,000 0,05010054 0,05030647 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,05060969 0,05079682 ! transcription initiation GO:0006352 171 97 0,000 0,05060969 0,05077596 ! regulation of protein localization GO:0032880 188 97 0,000 0,05060969 0,05075512 ! leukocyte differentiation GO:0002521 232 98 0,000 0,05111857 0,05124443 ! forebrain development GO:0030900 210 98 0,000 0,05111857 0,05122341 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,05111857 0,05120241 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,05213556 0,05219967 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,05213556 0,05217828 ! positive regulation of immune response GO:0050778 175 100 0,000 0,05213556 0,05215691 ! hormone metabolic process GO:0042445 171 100 0,000 0,05213556 0,05213556