pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/10915-0-real-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein ubiquitination GO:0031396 19 15 2,000 1,119E-07 2,574E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 3,003E-06 3,453E-03 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 4,314E-06 3,308E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 4,314E-06 2,481E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 5 1,000 4,314E-06 1,985E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 5,051E-06 1,936E-03 ! positive regulation of protein ubiquitination GO:0031398 8 6 1,000 6,469E-06 2,126E-03 ! positive regulation of DNA repair GO:0045739 7 6 1,000 6,469E-06 1,86E-03 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 6,469E-06 1,653E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 6,469E-06 1,488E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 9,053E-06 1,893E-03 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 1,000 9,053E-06 1,735E-03 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 9,053E-06 1,602E-03 ! positive regulation of Ras GTPase activity GO:0032320 20 8 1,000 1,207E-05 1,982E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 1,000 1,207E-05 1,85E-03 ! positive regulation of GTPase activity GO:0043547 21 9 1,000 1,551E-05 2,229E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 1,551E-05 2,098E-03 ! regulation of stress fiber formation GO:0051492 20 9 1,000 1,551E-05 1,982E-03 ! postreplication repair GO:0006301 11 9 1,000 1,551E-05 1,877E-03 ! positive regulation of protein modification process GO:0031401 107 78 2,000 1,826E-05 2,1E-03 ! regulation of phosphatase activity GO:0010921 21 10 1,000 1,938E-05 2,122E-03 ! negative regulation of lipid metabolic process GO:0045833 14 10 1,000 1,938E-05 2,026E-03 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 1,938E-05 1,938E-03 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 2,367E-05 2,269E-03 GO:0000725|recombinational repair, ! regulation of mRNA processing GO:0050684 18 11 1,000 2,367E-05 2,178E-03 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 2,367E-05 2,094E-03 ! cell cycle arrest GO:0007050 150 86 2,000 2,449E-05 2,086E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 2,449E-05 2,012E-03 ! interphase GO:0051325 159 88 2,000 2,624E-05 2,081E-03 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 3,097E-05 2,374E-03 ! regulation of DNA repair GO:0006282 15 13 1,000 3,355E-05 2,489E-03 ! regulation of lipid biosynthetic process GO:0046890 16 14 1,000 3,913E-05 2,812E-03 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 4,513E-05 3,145E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 4,513E-05 3,053E-03 ! centrosome cycle GO:0007098 16 15 1,000 4,513E-05 2,966E-03 ! cellular response to unfolded protein GO:0034620 19 16 1,000 5,156E-05 3,294E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 33 16 1,000 5,156E-05 3,205E-03 ! negative regulation of translation GO:0017148 22 16 1,000 5,156E-05 3,12E-03 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 5,841E-05 3,445E-03 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 7,338E-05 4,22E-03 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 7,338E-05 4,117E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 9,005E-05 4,931E-03 ! microtubule organizing center organization GO:0031023 28 22 1,000 9,902E-05 5,296E-03 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 9,902E-05 5,176E-03 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 9,902E-05 5,061E-03 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 1,084E-04 5,42E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 1,084E-04 5,305E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 1,084E-04 5,195E-03 ! fat cell differentiation GO:0045444 37 24 1,000 1,182E-04 5,549E-03 ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 1,284E-04 5,909E-03 ! negative regulation of protein modification process GO:0031400 50 26 1,000 1,391E-04 6,273E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 1,391E-04 6,152E-03 ! negative regulation of protein transport GO:0051224 49 27 1,000 1,502E-04 6,517E-03 ! positive regulation of catabolic process GO:0009896 40 28 1,000 1,617E-04 6,885E-03 ! tissue homeostasis GO:0001894 42 29 1,000 1,736E-04 7,258E-03 GO:0048871|multicellular organismal homeostasis, ! regulation of microtubule-based process GO:0032886 58 30 1,000 1,859E-04 7,635E-03 ! RNA export from nucleus GO:0006405 44 33 1,000 2,254E-04 9,094E-03 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 2,254E-04 8,937E-03 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 2,254E-04 8,786E-03 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 2,538E-04 9,728E-03 ! response to calcium ion GO:0051592 58 40 1,000 3,321E-04 0,01252029 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 3,321E-04 0,01231835 ! double-strand break repair GO:0006302 67 40 1,000 3,321E-04 0,01212282 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 3,663E-04 0,0131626 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 3,663E-04 0,01296009 ! response to insulin stimulus GO:0032868 63 43 1,000 3,84E-04 0,01338125 ! positive regulation of cell cycle GO:0045787 77 45 1,000 4,207E-04 0,01444049 ! response to UV GO:0009411 75 46 1,000 4,396E-04 0,01486919 ! response to estrogen stimulus GO:0043627 74 47 1,000 4,59E-04 0,01529913 ! nuclear export GO:0051168 69 48 1,000 4,787E-04 0,01573025 ! regulation of intracellular transport GO:0032386 78 49 1,000 4,989E-04 0,01616248 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 5,195E-04 0,01659575 ! regulation of protein catabolic process GO:0042176 77 51 1,000 5,405E-04 0,01703001 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 6,516E-04 0,02025296 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 6,516E-04 0,01998292 ! chromosome segregation GO:0007059 83 57 1,000 6,751E-04 0,02042929 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 6,751E-04 0,02016397 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 6,989E-04 0,02060851 ! regulation of cellular response to stress GO:0080135 85 61 1,000 7,728E-04 0,02250067 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 7,728E-04 0,02221941 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 7,983E-04 0,02266796 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 8,242E-04 0,02311685 ! cell cycle checkpoint GO:0000075 108 64 1,000 8,504E-04 0,02356606 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 8,504E-04 0,02328552 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 8,504E-04 0,02301157 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 8,771E-04 0,02345708 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 8,771E-04 0,02318746 ! regulation of actin filament-based process GO:0032970 99 66 1,000 9,042E-04 0,02363132 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 9,042E-04 0,0233658 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 9,595E-04 0,02452016 ! positive regulation of ligase activity GO:0051351 99 69 1,000 9,877E-04 0,02496509 ! response to metal ion GO:0010038 103 70 1,000 1,016E-03 0,02541033 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 1,016E-03 0,0251371 ! regulation of catabolic process GO:0009894 106 70 1,000 1,016E-03 0,02486968 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 1,045E-03 0,02531151 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 1,075E-03 0,02575368 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 1,075E-03 0,02548818 ! negative regulation of transport GO:0051051 116 73 1,000 1,105E-03 0,02592886 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 1,105E-03 0,02566695 ! response to inorganic substance GO:0010035 115 75 1,000 1,166E-03 0,02681118 ! regulation of ligase activity GO:0051340 114 75 1,000 1,166E-03 0,02654572 ! response to unfolded protein GO:0006986 99 76 1,000 1,197E-03 0,0269856 ! regulation of protein transport GO:0051223 114 76 1,000 1,197E-03 0,0267236 GO:0070201|regulation of establishment of protein localization, ! protein ubiquitination GO:0016567 125 77 1,000 1,228E-03 0,02716206 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 1,325E-03 0,02902169 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 1,000 1,325E-03 0,0287479 ! regulation of cell cycle process GO:0010564 122 81 1,000 1,358E-03 0,02918909 ! response to protein stimulus GO:0051789 111 81 1,000 1,358E-03 0,02891882 ! regulation of cell adhesion GO:0030155 159 83 1,000 1,425E-03 0,03007209 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 1,459E-03 0,03051386 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 1,494E-03 0,03095581 ! regulation of protein localization GO:0032880 132 85 1,000 1,494E-03 0,03067942 ! anatomical structure homeostasis GO:0060249 136 88 1,000 1,6E-03 0,03256819 ! establishment of RNA localization GO:0051236 128 88 1,000 1,6E-03 0,0322825 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein modification by small protein conjugation GO:0032446 140 90 1,000 1,673E-03 0,03345597 ! RNA localization GO:0006403 135 91 1,000 1,71E-03 0,03389997 ! DNA recombination GO:0006310 146 92 1,000 1,747E-03 0,03434402 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 1,9E-03 0,03703891 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 1,9E-03 0,03672766 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 1,9E-03 0,0364216 ! response to light stimulus GO:0009416 153 96 1,000 1,9E-03 0,03612059 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 2,019E-03 0,03806713 ! regulation of translation GO:0006417 151 100 1,000 2,06E-03 0,03851352 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 3,428E-03 0,06357988 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 3,428E-03 0,06307124 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 3,428E-03 0,06257067 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 3,428E-03 0,06207799 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,428E-03 0,06159301 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 3,428E-03 0,06111554 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 3,428E-03 0,06064542 ! sleep GO:0030431 11 5 0,000 3,428E-03 0,06018248 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,428E-03 0,05972655 ! nucleotide-sugar transport GO:0015780 8 5 0,000 3,428E-03 0,05927748 ! regulation of interferon-beta production GO:0032648 5 5 0,000 3,428E-03 0,05883511 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 3,428E-03 0,0583993 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 3,428E-03 0,05796989 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 3,428E-03 0,05754675 ! tongue development GO:0043586 6 5 0,000 3,428E-03 0,05712975 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 3,428E-03 0,05671874 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,428E-03 0,05631361 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 3,428E-03 0,05591422 ! cobalt ion transport GO:0006824 9 5 0,000 3,428E-03 0,05552046 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 3,428E-03 0,0551322 ! SMAD protein complex assembly GO:0007183 9 5 0,000 3,428E-03 0,05474934 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 3,428E-03 0,05437176 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 3,428E-03 0,05399935 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 3,428E-03 0,05363201 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 3,428E-03 0,05326963 ! embryonic camera-type eye development GO:0031076 8 5 0,000 3,428E-03 0,05291211 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 3,428E-03 0,05255937 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 3,428E-03 0,05221129 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,428E-03 0,0518678 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,428E-03 0,05152879 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,428E-03 0,05119419 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 3,428E-03 0,0508639 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 3,428E-03 0,05053785 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,428E-03 0,05021595 ! malate metabolic process GO:0006108 7 5 0,000 3,428E-03 0,04989813 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 3,428E-03 0,04958431 ! behavioral response to pain GO:0048266 7 5 0,000 3,428E-03 0,04927441 ! clathrin coat assembly GO:0048268 11 5 0,000 3,428E-03 0,04896835 ! phototransduction, visible light GO:0007603 6 5 0,000 3,428E-03 0,04866608 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,428E-03 0,04836751 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 3,428E-03 0,04807259 ! mating behavior GO:0007617 6 5 0,000 3,428E-03 0,04778124 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,428E-03 0,0474934 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 3,428E-03 0,04720901 ! rhythmic behavior GO:0007622 12 5 0,000 3,428E-03 0,04692801 ! copulation GO:0007620 7 5 0,000 3,428E-03 0,04665032 ! glial cell fate commitment GO:0021781 12 5 0,000 3,428E-03 0,04637591 ! protein maturation by protein folding GO:0022417 12 5 0,000 3,428E-03 0,04610471 ! embryonic hemopoiesis GO:0035162 10 5 0,000 3,428E-03 0,04583666 ! regulation of potassium ion transport GO:0043266 9 5 0,000 3,428E-03 0,0455717 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 3,428E-03 0,0453098 ! apoptotic cell clearance GO:0043277 13 5 0,000 3,428E-03 0,04505089 ! lipoprotein particle clearance GO:0034381 9 5 0,000 3,428E-03 0,04479491 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 3,428E-03 0,04454184 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,428E-03 0,0442916 ! response to protozoan GO:0001562 9 5 0,000 3,428E-03 0,04404416 ! positive regulation of glycolysis GO:0045821 11 5 0,000 3,428E-03 0,04379947 ! lymph vessel development GO:0001945 7 5 0,000 3,428E-03 0,04355749 ! endochondral ossification GO:0001958 12 5 0,000 3,428E-03 0,04331816 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 3,428E-03 0,04308145 ! parathyroid gland development GO:0060017 8 5 0,000 3,428E-03 0,04284731 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 3,428E-03 0,0426157 ! anagen GO:0042640 6 5 0,000 3,428E-03 0,04238659 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 3,428E-03 0,04215992 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 3,428E-03 0,04193566 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 3,428E-03 0,04171378 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 3,428E-03 0,04149424 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 3,428E-03 0,04127699 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 3,428E-03 0,041062 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 3,428E-03 0,04084925 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 3,428E-03 0,04063868 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 3,428E-03 0,04043028 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 3,428E-03 0,040224 ! cardiac muscle fiber development GO:0048739 7 5 0,000 3,428E-03 0,04001982 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 3,428E-03 0,0398177 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 3,428E-03 0,03961761 ! neutrophil mediated immunity GO:0002446 6 5 0,000 3,428E-03 0,03941952 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 3,428E-03 0,03922341 ! ovulation GO:0030728 6 5 0,000 3,428E-03 0,03902923 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 3,428E-03 0,03883697 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 3,428E-03 0,03864659 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 3,428E-03 0,03845807 ! response to pH GO:0009268 9 5 0,000 3,428E-03 0,03827138 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 3,428E-03 0,0380865 ! proline biosynthetic process GO:0006561 6 5 0,000 3,428E-03 0,03790339 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,428E-03 0,03772203 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 3,428E-03 0,0375424 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,428E-03 0,03736448 ! polyol catabolic process GO:0046174 7 5 0,000 3,428E-03 0,03718823 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 3,428E-03 0,03701364 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,428E-03 0,03684068 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,428E-03 0,03666933 ! sister chromatid cohesion GO:0007062 9 5 0,000 3,428E-03 0,03649956 ! nerve growth factor processing GO:0032455 7 5 0,000 3,428E-03 0,03633136 ! urea metabolic process GO:0019627 6 5 0,000 3,428E-03 0,0361647 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 3,428E-03 0,03599957 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,428E-03 0,03583593 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 3,428E-03 0,03567378 ! neutrophil activation GO:0042119 5 5 0,000 3,428E-03 0,03551309 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 3,428E-03 0,03535383 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 3,428E-03 0,035196 ! response to food GO:0032094 5 5 0,000 3,428E-03 0,03503958 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 3,428E-03 0,03488453 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,428E-03 0,03473086 ! paraxial mesoderm development GO:0048339 9 5 0,000 3,428E-03 0,03457853 ! forebrain neuron development GO:0021884 7 5 0,000 3,428E-03 0,03442753 ! melanosome organization GO:0032438 7 5 0,000 3,428E-03 0,03427785 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 3,428E-03 0,03412946 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 3,428E-03 0,03398235 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 3,428E-03 0,0338365 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,428E-03 0,0336919 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 3,428E-03 0,03354853 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 3,428E-03 0,03340638 ! nucleoside transport GO:0015858 6 5 0,000 3,428E-03 0,03326542 ! nucleoside salvage GO:0043174 7 5 0,000 3,428E-03 0,03312565 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 3,428E-03 0,03298705 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,428E-03 0,0328496 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 3,428E-03 0,0327133 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 3,428E-03 0,03257812 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,428E-03 0,03244405 ! early endosome to late endosome transport GO:0045022 11 5 0,000 3,428E-03 0,03231109 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,428E-03 0,0321792 ! depyrimidination GO:0045008 8 5 0,000 3,428E-03 0,03204839 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 3,428E-03 0,03191864 ! 5S class rRNA transcription GO:0042791 8 5 0,000 3,428E-03 0,03178994 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 3,428E-03 0,03166227 ! neuronal ion channel clustering GO:0045161 7 5 0,000 3,428E-03 0,03153562 ! sodium ion homeostasis GO:0055078 6 5 0,000 3,428E-03 0,03140998 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 3,428E-03 0,03128534 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 3,428E-03 0,03116168 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 3,428E-03 0,031039 ! monocyte differentiation GO:0030224 8 5 0,000 3,428E-03 0,03091727 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 3,428E-03 0,0307965 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 3,428E-03 0,03067667 ! centrosome duplication GO:0051298 5 5 0,000 3,428E-03 0,03055777 ! response to UV-C GO:0010225 6 5 0,000 3,428E-03 0,03043979 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 3,428E-03 0,03032271 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 3,428E-03 0,03020653 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 3,428E-03 0,03009124 ! regulation of dendrite development GO:0050773 12 5 0,000 3,428E-03 0,02997682 ! peptidyl-arginine modification GO:0018195 7 5 0,000 3,428E-03 0,02986328 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,428E-03 0,02975058 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 3,428E-03 0,02963874 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 3,428E-03 0,02952773 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 3,428E-03 0,02941756 ! regulation of dopamine secretion GO:0014059 12 5 0,000 3,428E-03 0,0293082 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 3,428E-03 0,02919965 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 3,428E-03 0,0290919 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 3,428E-03 0,02898494 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,428E-03 0,02887877 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 3,428E-03 0,02877338 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,428E-03 0,02866875 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 3,428E-03 0,02856487 ! neural tube patterning GO:0021532 6 5 0,000 3,428E-03 0,02846175 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 3,428E-03 0,02835937 ! histone demethylation GO:0016577 9 5 0,000 3,428E-03 0,02825772 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 3,428E-03 0,0281568 ! regulation of sterol transport GO:0032371 7 5 0,000 3,428E-03 0,0280566 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 3,428E-03 0,02795711 ! enteric nervous system development GO:0048484 8 5 0,000 3,428E-03 0,02785832 ! establishment of planar polarity GO:0001736 6 5 0,000 3,428E-03 0,02776023 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 3,428E-03 0,02766282 ! muscle cell proliferation GO:0033002 8 5 0,000 3,428E-03 0,0275661 ! transcription termination GO:0006353 8 5 0,000 3,428E-03 0,02747005 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 3,428E-03 0,02737467 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 3,428E-03 0,02727995 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 3,428E-03 0,02718588 ! regulation of respiratory burst GO:0060263 8 5 0,000 3,428E-03 0,02709246 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 3,428E-03 0,02699967 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,428E-03 0,02690753 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,428E-03 0,026816 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 3,428E-03 0,0267251 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 3,428E-03 0,02663481 ! apical protein localization GO:0045176 6 5 0,000 3,428E-03 0,02654513 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 3,428E-03 0,02645606 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 3,428E-03 0,02636757 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,428E-03 0,02627968 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 3,428E-03 0,02619238 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 3,428E-03 0,02610565 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 3,428E-03 0,02601949 ! triglyceride catabolic process GO:0019433 6 5 0,000 3,428E-03 0,0259339 ! glial cell migration GO:0008347 10 5 0,000 3,428E-03 0,02584887 ! determination of adult lifespan GO:0008340 8 5 0,000 3,428E-03 0,0257644 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 3,428E-03 0,02568047 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 3,428E-03 0,02559709 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,428E-03 0,02551426 ! somatic stem cell maintenance GO:0035019 13 5 0,000 3,428E-03 0,02543195 ! cerebellar cortex formation GO:0021697 6 5 0,000 3,428E-03 0,02535018 ! neural plate development GO:0001840 6 5 0,000 3,428E-03 0,02526893 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 3,428E-03 0,02518819 ! regulation of sensory perception GO:0051931 6 5 0,000 3,428E-03 0,02510798 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 3,428E-03 0,02502827 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 3,428E-03 0,02494907 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 3,428E-03 0,02487036 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 3,428E-03 0,02479215 ! sensory cilium assembly GO:0035058 6 5 0,000 3,428E-03 0,02471444 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 3,428E-03 0,0246372 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,428E-03 0,02456045 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 3,428E-03 0,02448418 ! spindle assembly GO:0051225 5 5 0,000 3,428E-03 0,02440837 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 3,428E-03 0,02433304 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 3,428E-03 0,02425817 ! protein amino acid prenylation GO:0018346 9 5 0,000 3,428E-03 0,02418376 ! organ regeneration GO:0031100 7 5 0,000 3,428E-03 0,0241098 ! NAD biosynthetic process GO:0009435 7 5 0,000 3,428E-03 0,0240363 ! carnitine metabolic process GO:0009437 5 5 0,000 3,428E-03 0,02396324 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 3,428E-03 0,02389062 ! cellular anion homeostasis GO:0030002 6 5 0,000 3,428E-03 0,02381844 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 11 6 0,000 4,112E-03 0,02848708 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 4,112E-03 0,02840153 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 4,112E-03 0,0283165 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 4,112E-03 0,02823197 GO:0030816|positive regulation of cAMP metabolic process, ! regulation of helicase activity GO:0051095 11 6 0,000 4,112E-03 0,02814795 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 4,112E-03 0,02806442 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 4,112E-03 0,02798139 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 4,112E-03 0,02789885 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 4,112E-03 0,02781679 ! positive regulation of axon extension GO:0045773 8 6 0,000 4,112E-03 0,02773522 ! prostate gland development GO:0030850 9 6 0,000 4,112E-03 0,02765412 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 4,112E-03 0,0275735 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 4,112E-03 0,02749334 ! forebrain neuron differentiation GO:0021879 9 6 0,000 4,112E-03 0,02741365 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 4,112E-03 0,02733442 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 4,112E-03 0,02725565 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 4,112E-03 0,02717733 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 4,112E-03 0,02709946 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 4,112E-03 0,02702203 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 4,112E-03 0,02694504 ! neuron adhesion GO:0007158 9 6 0,000 4,112E-03 0,02686849 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 4,112E-03 0,02679238 ! establishment of tissue polarity GO:0007164 7 6 0,000 4,112E-03 0,0267167 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 4,112E-03 0,02664144 ! signal peptide processing GO:0006465 8 6 0,000 4,112E-03 0,0265666 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 4,112E-03 0,02649219 ! mRNA stabilization GO:0048255 15 6 0,000 4,112E-03 0,02641818 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 4,112E-03 0,0263446 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 4,112E-03 0,02627142 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 4,112E-03 0,02619864 ! opsonization GO:0008228 8 6 0,000 4,112E-03 0,02612627 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 4,112E-03 0,0260543 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 4,112E-03 0,02598272 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 4,112E-03 0,02591153 ! protein amino acid dealkylation GO:0008214 11 6 0,000 4,112E-03 0,02584074 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 4,112E-03 0,02577033 ! photoreceptor cell development GO:0042461 10 6 0,000 4,112E-03 0,0257003 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 4,112E-03 0,02563065 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 4,112E-03 0,02556138 ! mechanosensory behavior GO:0007638 8 6 0,000 4,112E-03 0,02549248 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 4,112E-03 0,02542395 ! negative regulation of endocytosis GO:0045806 8 6 0,000 4,112E-03 0,02535579 ! response to interferon-gamma GO:0034341 12 6 0,000 4,112E-03 0,02528799 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 4,112E-03 0,02522056 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 4,112E-03 0,02515348 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 4,112E-03 0,02508676 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 4,112E-03 0,0250204 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 4,112E-03 0,02495438 ! cGMP-mediated signaling GO:0019934 10 6 0,000 4,112E-03 0,02488871 ! activation of MAPKKK activity GO:0000185 10 6 0,000 4,112E-03 0,02482339 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 4,112E-03 0,0247584 ! thymic T cell selection GO:0045061 12 6 0,000 4,112E-03 0,02469376 ! protein lipoylation GO:0009249 10 6 0,000 4,112E-03 0,02462945 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 4,112E-03 0,02456548 ! pigment granule organization GO:0048753 11 6 0,000 4,112E-03 0,02450184 ! drug transport GO:0015893 6 6 0,000 4,112E-03 0,02443853 ! cysteine metabolic process GO:0006534 7 6 0,000 4,112E-03 0,02437554 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 4,112E-03 0,02431288 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 4,112E-03 0,02425054 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 4,112E-03 0,02418852 ! histidine metabolic process GO:0006547 6 6 0,000 4,112E-03 0,02412681 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 4,112E-03 0,02406542 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 4,112E-03 0,02400434 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 4,112E-03 0,02394357 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 4,112E-03 0,02388311 ! adenohypophysis development GO:0021984 10 6 0,000 4,112E-03 0,02382295 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 4,112E-03 0,02376309 ! hyperosmotic response GO:0006972 8 6 0,000 4,112E-03 0,02370353 ! microtubule nucleation GO:0007020 10 6 0,000 4,112E-03 0,02364428 ! ER overload response GO:0006983 7 6 0,000 4,112E-03 0,02358531 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 4,112E-03 0,02352664 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 4,112E-03 0,02346826 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 4,112E-03 0,02341017 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 4,112E-03 0,02335237 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 4,112E-03 0,02329485 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 4,112E-03 0,02323762 ! response to dietary excess GO:0002021 7 6 0,000 4,112E-03 0,02318066 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 4,112E-03 0,02312399 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 4,112E-03 0,02306759 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 4,112E-03 0,02301146 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 4,112E-03 0,02295561 ! glycerol ether catabolic process GO:0044269 8 6 0,000 4,112E-03 0,02290002 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 4,112E-03 0,02284471 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 4,112E-03 0,02278966 ! neuron apoptosis GO:0051402 8 6 0,000 4,112E-03 0,02273488 ! organic alcohol transport GO:0015850 9 6 0,000 4,112E-03 0,02268036 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 4,112E-03 0,0226261 ! T cell mediated immunity GO:0002456 12 6 0,000 4,112E-03 0,0225721 ! male sex determination GO:0030238 9 6 0,000 4,112E-03 0,02251836 ! carnitine transport GO:0015879 8 6 0,000 4,112E-03 0,02246487 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 4,112E-03 0,02241164 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 4,112E-03 0,02235865 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,112E-03 0,02230592 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 4,112E-03 0,02225344 ! positive regulation of exocytosis GO:0045921 6 6 0,000 4,112E-03 0,0222012 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 4,112E-03 0,0221492 ! parturition GO:0007567 12 6 0,000 4,112E-03 0,02209745 ! negative regulation of translational initiation GO:0045947 7 6 0,000 4,112E-03 0,02204594 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 4,112E-03 0,02199467 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 4,112E-03 0,02194364 ! spindle checkpoint GO:0031577 14 6 0,000 4,112E-03 0,02189285 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 4,112E-03 0,02184229 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 4,112E-03 0,02179196 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 4,112E-03 0,02174186 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 4,112E-03 0,021692 ! macrophage differentiation GO:0030225 10 6 0,000 4,112E-03 0,02164236 ! astrocyte development GO:0014002 14 6 0,000 4,112E-03 0,02159295 ! hyaluronan metabolic process GO:0030212 6 6 0,000 4,112E-03 0,02154376 ! purine base biosynthetic process GO:0009113 14 6 0,000 4,112E-03 0,0214948 ! interaction with symbiont GO:0051702 8 6 0,000 4,112E-03 0,02144605 ! anterograde axon cargo transport GO:0008089 8 6 0,000 4,112E-03 0,02139753 ! skeletal muscle contraction GO:0003009 6 6 0,000 4,112E-03 0,02134923 ! eating behavior GO:0042755 6 6 0,000 4,112E-03 0,02130115 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 4,112E-03 0,02125328 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 4,112E-03 0,02120563 ! response to copper ion GO:0046688 9 6 0,000 4,112E-03 0,02115819 ! DNA topological change GO:0006265 8 6 0,000 4,112E-03 0,02111096 ! response to exogenous dsRNA GO:0043330 8 6 0,000 4,112E-03 0,02106394 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 4,112E-03 0,02101713 ! establishment of melanosome localization GO:0032401 9 6 0,000 4,112E-03 0,02097053 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,112E-03 0,02092414 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 4,112E-03 0,02087795 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 4,112E-03 0,02083196 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 4,112E-03 0,02078618 ! nucleoside catabolic process GO:0009164 6 6 0,000 4,112E-03 0,02074059 ! gas homeostasis GO:0033483 11 6 0,000 4,112E-03 0,02069521 ! hair follicle maturation GO:0048820 7 6 0,000 4,112E-03 0,02065002 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 4,112E-03 0,02060503 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 4,112E-03 0,02056024 ! Schwann cell development GO:0014044 14 6 0,000 4,112E-03 0,02051564 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 4,112E-03 0,02047123 ! dendrite morphogenesis GO:0048813 9 6 0,000 4,112E-03 0,02042702 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 4,112E-03 0,020383 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 4,112E-03 0,02033916 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 4,112E-03 0,02029552 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 4,112E-03 0,02025206 ! histone ubiquitination GO:0016574 7 6 0,000 4,112E-03 0,02020878 ! regulation of meiosis GO:0040020 10 6 0,000 4,112E-03 0,02016569 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 4,112E-03 0,02012279 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 4,112E-03 0,02008006 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 4,112E-03 0,02003752 ! regulation of mast cell activation GO:0033003 6 6 0,000 4,112E-03 0,01999516 ! membrane to membrane docking GO:0022614 12 6 0,000 4,112E-03 0,01995297 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 4,112E-03 0,01991097 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 4,112E-03 0,01986914 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 4,112E-03 0,01982748 ! receptor internalization GO:0031623 9 6 0,000 4,112E-03 0,019786 ! neutrophil homeostasis GO:0001780 6 6 0,000 4,112E-03 0,0197447 ! coenzyme A metabolic process GO:0015936 9 6 0,000 4,112E-03 0,01970356 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,112E-03 0,0196626 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 4,112E-03 0,01962181 ! protein deubiquitination GO:0016579 8 6 0,000 4,112E-03 0,01958118 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 4,112E-03 0,01954072 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 4,112E-03 0,01950043 ! peptidyl-histidine modification GO:0018202 9 6 0,000 4,112E-03 0,01946031 ! axonal fasciculation GO:0007413 9 6 0,000 4,112E-03 0,01942035 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 4,112E-03 0,01938055 ! thiamin metabolic process GO:0006772 6 6 0,000 4,112E-03 0,01934092 ! midbrain development GO:0030901 6 6 0,000 4,112E-03 0,01930145 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 4,112E-03 0,01926214 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 4,112E-03 0,01922299 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 4,112E-03 0,019184 ! progesterone metabolic process GO:0042448 8 6 0,000 4,112E-03 0,01914516 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 4,112E-03 0,01910648 ! glycolipid catabolic process GO:0019377 13 6 0,000 4,112E-03 0,01906796 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 4,112E-03 0,0190296 ! positive regulation of glucose import GO:0046326 6 6 0,000 4,112E-03 0,01899139 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 4,112E-03 0,01895333 ! adult feeding behavior GO:0008343 6 6 0,000 4,112E-03 0,01891542 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 4,112E-03 0,01887766 ! blastocyst growth GO:0001832 15 6 0,000 4,112E-03 0,01884006 ! pigment granule transport GO:0051904 12 6 0,000 4,112E-03 0,0188026 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 4,112E-03 0,0187653 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 4,112E-03 0,01872814 ! catecholamine transport GO:0051937 7 6 0,000 4,112E-03 0,01869113 ! organ or tissue specific immune response GO:0002251 7 6 0,000 4,112E-03 0,01865426 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 4,112E-03 0,01861754 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 4,112E-03 0,01858096 ! negative regulation of B cell activation GO:0050869 9 6 0,000 4,112E-03 0,01854453 ! protein prenylation GO:0018342 10 6 0,000 4,112E-03 0,01850824 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 4,112E-03 0,01847209 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 4,112E-03 0,01843608 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 4,112E-03 0,01840021 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 4,112E-03 0,01836449 ! positive regulation of coagulation GO:0050820 11 6 0,000 4,112E-03 0,0183289 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 4,796E-03 0,02133564 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 4,796E-03 0,02129445 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 4,796E-03 0,02125342 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 4,796E-03 0,02121255 ! synaptonemal complex assembly GO:0007130 10 7 0,000 4,796E-03 0,02117183 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 4,796E-03 0,02113127 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 4,796E-03 0,02109087 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 4,796E-03 0,02105062 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 4,796E-03 0,02101052 ! reproductive behavior GO:0019098 12 7 0,000 4,796E-03 0,02097058 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 4,796E-03 0,02093079 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 4,796E-03 0,02089115 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 4,796E-03 0,02085165 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 4,796E-03 0,02081231 ! oligopeptide transport GO:0006857 11 7 0,000 4,796E-03 0,02077312 ! protein amino acid sulfation GO:0006477 9 7 0,000 4,796E-03 0,02073407 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 4,796E-03 0,02069517 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 4,796E-03 0,02065641 ! RNA methylation GO:0001510 11 7 0,000 4,796E-03 0,0206178 ! pericardium development GO:0060039 8 7 0,000 4,796E-03 0,02057934 ! macrophage chemotaxis GO:0048246 10 7 0,000 4,796E-03 0,02054101 ! fibril organization GO:0043206 13 7 0,000 4,796E-03 0,02050283 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 4,796E-03 0,0204648 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 4,796E-03 0,0204269 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 4,796E-03 0,02038914 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 4,796E-03 0,02035152 ! lipoprotein transport GO:0042953 9 7 0,000 4,796E-03 0,02031404 ! cerebral cortex cell migration GO:0021795 11 7 0,000 4,796E-03 0,0202767 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 4,796E-03 0,02023949 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 4,796E-03 0,02020243 ! estrogen metabolic process GO:0008210 14 7 0,000 4,796E-03 0,02016549 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 4,796E-03 0,02012869 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 4,796E-03 0,02009203 ! chemosensory behavior GO:0007635 9 7 0,000 4,796E-03 0,0200555 ! microtubule bundle formation GO:0001578 8 7 0,000 4,796E-03 0,0200191 ! T-helper 1 type immune response GO:0042088 11 7 0,000 4,796E-03 0,01998283 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 4,796E-03 0,0199467 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 4,796E-03 0,01991069 ! leukocyte degranulation GO:0043299 10 7 0,000 4,796E-03 0,01987482 ! bile acid and bile salt transport GO:0015721 9 7 0,000 4,796E-03 0,01983907 ! reflex GO:0060004 12 7 0,000 4,796E-03 0,01980346 ! positive regulation of isotype switching GO:0045830 15 7 0,000 4,796E-03 0,01976797 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 4,796E-03 0,0197326 ! protein-cofactor linkage GO:0018065 13 7 0,000 4,796E-03 0,01969737 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 4,796E-03 0,01966225 ! glycerolipid catabolic process GO:0046503 9 7 0,000 4,796E-03 0,01962727 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 4,796E-03 0,01959241 ! spinal cord patterning GO:0021511 7 7 0,000 4,796E-03 0,01955767 ! hemoglobin metabolic process GO:0020027 10 7 0,000 4,796E-03 0,01952305 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 4,796E-03 0,01948856 ! adrenal gland development GO:0030325 17 7 0,000 4,796E-03 0,01945419 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 4,796E-03 0,01941994 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 4,796E-03 0,01938581 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 4,796E-03 0,0193518 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 4,796E-03 0,01931791 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 4,796E-03 0,01928413 ! endosome organization GO:0007032 10 7 0,000 4,796E-03 0,01925048 ! thyroid hormone generation GO:0006590 11 7 0,000 4,796E-03 0,01921694 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 4,796E-03 0,01918352 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 4,796E-03 0,01915022 ! regulation of pigmentation during development GO:0048070 15 7 0,000 4,796E-03 0,01911703 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 4,796E-03 0,01908395 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 4,796E-03 0,01905099 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 4,796E-03 0,01901815 ! galactose metabolic process GO:0006012 10 7 0,000 4,796E-03 0,01898541 ! vesicle fusion GO:0006906 15 7 0,000 4,796E-03 0,01895279 ! intracellular pH reduction GO:0051452 10 7 0,000 4,796E-03 0,01892028 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 4,796E-03 0,01888788 ! organ growth GO:0035265 11 7 0,000 4,796E-03 0,0188556 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 4,796E-03 0,01882342 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 4,796E-03 0,01879135 ! Rac protein signal transduction GO:0016601 7 7 0,000 4,796E-03 0,0187594 ! retinol metabolic process GO:0042572 9 7 0,000 4,796E-03 0,01872755 ! behavioral fear response GO:0001662 13 7 0,000 4,796E-03 0,0186958 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 4,796E-03 0,01866417 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 4,796E-03 0,01863264 ! rRNA modification GO:0000154 12 7 0,000 4,796E-03 0,01860122 ! protein heterooligomerization GO:0051291 10 7 0,000 4,796E-03 0,01856991 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 4,796E-03 0,0185387 ! response to UV-B GO:0010224 11 7 0,000 4,796E-03 0,01850759 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 4,796E-03 0,01847659 ! protein retention in ER lumen GO:0006621 12 7 0,000 4,796E-03 0,01844569 ! intermediate filament organization GO:0045109 11 7 0,000 4,796E-03 0,0184149 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 4,796E-03 0,01838421 ! cardiac muscle cell development GO:0055013 9 7 0,000 4,796E-03 0,01835362 ! fibrinolysis GO:0042730 9 7 0,000 4,796E-03 0,01832313 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 4,796E-03 0,01829274 ! regulation of circadian rhythm GO:0042752 11 7 0,000 4,796E-03 0,01826246 ! B cell lineage commitment GO:0002326 17 7 0,000 4,796E-03 0,01823227 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 4,796E-03 0,01820219 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 4,796E-03 0,0181722 ! response to tropane GO:0014073 13 7 0,000 4,796E-03 0,01814231 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 4,796E-03 0,01811252 ! melanosome localization GO:0032400 10 7 0,000 4,796E-03 0,01808283 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 4,796E-03 0,01805323 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 4,796E-03 0,01802373 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 4,796E-03 0,01799433 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 4,796E-03 0,01796502 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 4,796E-03 0,01793581 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 4,796E-03 0,0179067 ! mast cell activation GO:0045576 9 7 0,000 4,796E-03 0,01787767 ! multicellular organismal aging GO:0010259 11 7 0,000 4,796E-03 0,01784875 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 4,796E-03 0,01781991 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 4,796E-03 0,01779117 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 4,796E-03 0,01776252 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 4,796E-03 0,01773396 ! establishment of nucleus localization GO:0040023 13 7 0,000 4,796E-03 0,0177055 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 4,796E-03 0,01767712 ! T cell lineage commitment GO:0002360 12 7 0,000 4,796E-03 0,01764884 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 4,796E-03 0,01762065 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 4,796E-03 0,01759254 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 4,796E-03 0,01756453 ! regulation of lipid transport GO:0032368 13 7 0,000 4,796E-03 0,01753661 ! response to tumor cell GO:0002347 12 7 0,000 4,796E-03 0,01750877 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 4,796E-03 0,01748102 ! neuroblast proliferation GO:0007405 13 7 0,000 4,796E-03 0,01745336 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 4,796E-03 0,01742579 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 4,796E-03 0,0173983 ! peptidyl-threonine modification GO:0018210 18 7 0,000 4,796E-03 0,0173709 ! diuresis GO:0030146 12 7 0,000 4,796E-03 0,01734359 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 4,796E-03 0,01731637 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 4,796E-03 0,01728922 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 4,796E-03 0,01726217 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 4,796E-03 0,01723519 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 4,796E-03 0,01720831 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 4,796E-03 0,0171815 ! melanin biosynthetic process GO:0042438 8 7 0,000 4,796E-03 0,01715478 ! regulation of synaptogenesis GO:0051963 10 7 0,000 4,796E-03 0,01712814 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 4,796E-03 0,01710159 ! dopamine biosynthetic process GO:0042416 15 7 0,000 4,796E-03 0,01707512 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 4,796E-03 0,01704872 ! lymph node development GO:0048535 9 7 0,000 4,796E-03 0,01702241 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 4,796E-03 0,01699619 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 4,796E-03 0,01697004 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 4,796E-03 0,01694397 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 4,796E-03 0,01691798 ! endosome to lysosome transport GO:0008333 10 7 0,000 4,796E-03 0,01689207 ! ATP catabolic process GO:0006200 10 7 0,000 4,796E-03 0,01686625 ! establishment of pigment granule localization GO:0051905 13 7 0,000 4,796E-03 0,0168405 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 4,796E-03 0,01681482 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 4,796E-03 0,01678923 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 4,796E-03 0,01676372 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 4,796E-03 0,01673828 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 4,796E-03 0,01671292 ! muscle adaptation GO:0043500 12 7 0,000 4,796E-03 0,01668763 ! amino sugar catabolic process GO:0046348 9 7 0,000 4,796E-03 0,01666242 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 4,796E-03 0,01663729 ! retina homeostasis GO:0001895 9 7 0,000 4,796E-03 0,01661224 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 4,796E-03 0,01658726 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 4,796E-03 0,01656235 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 4,796E-03 0,01653752 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 4,796E-03 0,01651276 ! behavioral response to nicotine GO:0035095 11 7 0,000 4,796E-03 0,01648808 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 4,796E-03 0,01646347 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 4,796E-03 0,01643893 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 5,479E-03 0,0187535 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 5,479E-03 0,01872563 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 5,479E-03 0,01869785 ! axon extension GO:0048675 11 8 0,000 5,479E-03 0,01867015 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 5,479E-03 0,01864253 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 5,479E-03 0,01861499 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 5,479E-03 0,01858754 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 5,479E-03 0,01856016 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 5,479E-03 0,01853287 ! cell proliferation in forebrain GO:0021846 10 8 0,000 5,479E-03 0,01850565 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 5,479E-03 0,01847852 ! phosphate transport GO:0006817 10 8 0,000 5,479E-03 0,01845146 ! N-glycan processing GO:0006491 12 8 0,000 5,479E-03 0,01842449 ! Golgi to endosome transport GO:0006895 16 8 0,000 5,479E-03 0,01839759 ! UTP metabolic process GO:0046051 8 8 0,000 5,479E-03 0,01837077 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 5,479E-03 0,01834403 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 5,479E-03 0,01831737 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 5,479E-03 0,01829078 ! neurotransmitter uptake GO:0001504 10 8 0,000 5,479E-03 0,01826427 ! succinate metabolic process GO:0006105 14 8 0,000 5,479E-03 0,01823784 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 5,479E-03 0,01821149 ! smoothened signaling pathway GO:0007224 8 8 0,000 5,479E-03 0,01818521 ! membrane hyperpolarization GO:0060081 10 8 0,000 5,479E-03 0,018159 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 5,479E-03 0,01813288 ! keratinocyte proliferation GO:0043616 12 8 0,000 5,479E-03 0,01810682 ! middle ear morphogenesis GO:0042474 9 8 0,000 5,479E-03 0,01808085 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 5,479E-03 0,01805494 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 5,479E-03 0,01802911 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 5,479E-03 0,01800336 ! ganglioside metabolic process GO:0001573 15 8 0,000 5,479E-03 0,01797767 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 5,479E-03 0,01795206 ! pseudouridine synthesis GO:0001522 9 8 0,000 5,479E-03 0,01792653 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 5,479E-03 0,01790106 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 5,479E-03 0,01787567 ! endothelial cell differentiation GO:0045446 14 8 0,000 5,479E-03 0,01785035 ! ceramide biosynthetic process GO:0046513 9 8 0,000 5,479E-03 0,0178251 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 5,479E-03 0,01779993 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 5,479E-03 0,01777482 ! astrocyte differentiation GO:0048708 16 8 0,000 5,479E-03 0,01774979 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 5,479E-03 0,01772482 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 5,479E-03 0,01769993 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 5,479E-03 0,0176751 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 5,479E-03 0,01765035 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 5,479E-03 0,01762566 ! melanin metabolic process GO:0006582 12 8 0,000 5,479E-03 0,01760105 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 5,479E-03 0,0175765 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 5,479E-03 0,01755202 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 5,479E-03 0,01752761 ! macrophage activation GO:0042116 12 8 0,000 5,479E-03 0,01750326 ! regulation of type I interferon production GO:0032479 8 8 0,000 5,479E-03 0,01747899 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 5,479E-03 0,01745478 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 5,479E-03 0,01743064 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 5,479E-03 0,01740656 ! regulation of vascular permeability GO:0043114 12 8 0,000 5,479E-03 0,01738255 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 5,479E-03 0,01735861 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 5,479E-03 0,01733473 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 5,479E-03 0,01731092 ! ruffle organization GO:0031529 11 8 0,000 5,479E-03 0,01728717 ! osteoblast development GO:0002076 13 8 0,000 5,479E-03 0,01726349 ! lens development in camera-type eye GO:0002088 10 8 0,000 5,479E-03 0,01723988 ! positive regulation of vasodilation GO:0045909 12 8 0,000 5,479E-03 0,01721632 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 5,479E-03 0,01719284 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 5,479E-03 0,01716941 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 5,479E-03 0,01714605 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 5,479E-03 0,01712276 ! Schwann cell differentiation GO:0014037 17 8 0,000 5,479E-03 0,01709952 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 5,479E-03 0,01707635 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 5,479E-03 0,01705325 ! regulation of gliogenesis GO:0014013 20 8 0,000 5,479E-03 0,0170302 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 5,479E-03 0,01700722 ! oligodendrocyte development GO:0014003 8 8 0,000 5,479E-03 0,0169843 ! segment specification GO:0007379 10 8 0,000 5,479E-03 0,01696144 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 5,479E-03 0,01693864 ! cellular extravasation GO:0045123 11 8 0,000 5,479E-03 0,0169159 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 5,479E-03 0,01689323 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 5,479E-03 0,01687061 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 5,479E-03 0,01684806 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 5,479E-03 0,01682557 ! snRNA metabolic process GO:0016073 10 8 0,000 5,479E-03 0,01680313 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 5,479E-03 0,01678076 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 5,479E-03 0,01675844 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 5,479E-03 0,01673619 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 5,479E-03 0,01671399 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 5,479E-03 0,01669185 ! nucleosome disassembly GO:0006337 12 8 0,000 5,479E-03 0,01666977 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 5,479E-03 0,01664775 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! protein import into peroxisome matrix GO:0016558 14 8 0,000 5,479E-03 0,01662579 ! icosanoid secretion GO:0032309 12 8 0,000 5,479E-03 0,01660389 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 5,479E-03 0,01658204 ! leukocyte activation during immune response GO:0002366 13 8 0,000 5,479E-03 0,01656025 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 5,479E-03 0,01653852 ! cerebellum morphogenesis GO:0021587 9 8 0,000 5,479E-03 0,01651684 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 5,479E-03 0,01649522 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 5,479E-03 0,01647366 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 5,479E-03 0,01645215 ! sterol catabolic process GO:0016127 9 8 0,000 5,479E-03 0,0164307 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 5,479E-03 0,01640931 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 5,479E-03 0,01638797 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 5,479E-03 0,01636669 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 5,479E-03 0,01634546 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 5,479E-03 0,01632429 ! prophase GO:0051324 11 8 0,000 5,479E-03 0,01630317 ! S phase GO:0051320 8 8 0,000 5,479E-03 0,0162821 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 5,479E-03 0,0162611 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 5,479E-03 0,01624014 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 5,479E-03 0,01621924 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 5,479E-03 0,01619839 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 5,479E-03 0,0161776 ! hormone catabolic process GO:0042447 13 8 0,000 5,479E-03 0,01615686 ! quaternary ammonium group transport GO:0015697 10 8 0,000 5,479E-03 0,01613617 ! myeloid cell homeostasis GO:0002262 8 8 0,000 5,479E-03 0,01611554 ! regulation of fibrinolysis GO:0051917 13 8 0,000 5,479E-03 0,01609495 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 5,479E-03 0,01607442 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 5,479E-03 0,01605395 ! regulation of telomere maintenance GO:0032204 10 8 0,000 5,479E-03 0,01603352 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 5,479E-03 0,01601315 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 5,479E-03 0,01599283 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 5,479E-03 0,01597256 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 5,479E-03 0,01595234 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 5,479E-03 0,01593217 ! lamellipodium assembly GO:0030032 9 8 0,000 5,479E-03 0,01591206 ! regulation of embryonic development GO:0045995 16 8 0,000 5,479E-03 0,01589199 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 5,479E-03 0,01587198 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 5,479E-03 0,01585201 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 5,479E-03 0,0158321 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 6,162E-03 0,01778317 ! regulation of developmental growth GO:0048638 13 9 0,000 6,162E-03 0,01776088 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 6,162E-03 0,01773865 ! telencephalon cell migration GO:0022029 16 9 0,000 6,162E-03 0,01771648 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 6,162E-03 0,01769436 ! pentose-phosphate shunt GO:0006098 12 9 0,000 6,162E-03 0,0176723 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 6,162E-03 0,01765029 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 6,162E-03 0,01762834 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 6,162E-03 0,01760644 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 6,162E-03 0,0175846 ! GTP metabolic process GO:0046039 9 9 0,000 6,162E-03 0,01756281 ! elastic fiber assembly GO:0048251 13 9 0,000 6,162E-03 0,01754107 ! social behavior GO:0035176 14 9 0,000 6,162E-03 0,01751939 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 6,162E-03 0,01749776 ! artery development GO:0060840 19 9 0,000 6,162E-03 0,01747618 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 6,162E-03 0,01745466 ! regulation of glycolysis GO:0006110 15 9 0,000 6,162E-03 0,01743319 ! response to pain GO:0048265 16 9 0,000 6,162E-03 0,01741177 ! protein complex disassembly GO:0043241 17 9 0,000 6,162E-03 0,01739041 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 6,162E-03 0,0173691 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 6,162E-03 0,01734784 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 6,162E-03 0,01732663 ! lung alveolus development GO:0048286 17 9 0,000 6,162E-03 0,01730548 ! ciliary or flagellar motility GO:0001539 10 9 0,000 6,162E-03 0,01728437 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 6,162E-03 0,01726332 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 6,162E-03 0,01724232 ! regulation of exit from mitosis GO:0007096 12 9 0,000 6,162E-03 0,01722137 ! ventral spinal cord development GO:0021517 11 9 0,000 6,162E-03 0,01720047 ! protein targeting to ER GO:0045047 19 9 0,000 6,162E-03 0,01717962 ! T cell selection GO:0045058 18 9 0,000 6,162E-03 0,01715882 ! endoderm development GO:0007492 12 9 0,000 6,162E-03 0,01713807 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 6,162E-03 0,01711737 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 6,162E-03 0,01709672 ! arginine catabolic process GO:0006527 10 9 0,000 6,162E-03 0,01707613 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 6,162E-03 0,01705558 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 6,162E-03 0,01703508 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 6,162E-03 0,01701463 ! phosphagen metabolic process GO:0006599 12 9 0,000 6,162E-03 0,01699423 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 6,162E-03 0,01697387 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 6,162E-03 0,01695357 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 6,162E-03 0,01693331 ! mannose metabolic process GO:0006013 9 9 0,000 6,162E-03 0,01691311 ! substrate-bound cell migration GO:0006929 10 9 0,000 6,162E-03 0,01689295 ! receptor clustering GO:0043113 15 9 0,000 6,162E-03 0,01687284 ! epithelial cell development GO:0002064 10 9 0,000 6,162E-03 0,01685278 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 6,162E-03 0,01683276 ! retinoic acid metabolic process GO:0042573 11 9 0,000 6,162E-03 0,01681279 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 6,162E-03 0,01679287 ! positive regulation of translational initiation GO:0045948 10 9 0,000 6,162E-03 0,016773 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 6,162E-03 0,01675317 ! motor axon guidance GO:0008045 14 9 0,000 6,162E-03 0,01673339 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 6,162E-03 0,01671366 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 6,162E-03 0,01669397 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 6,162E-03 0,01667433 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 6,162E-03 0,01665474 ! blastoderm segmentation GO:0007350 11 9 0,000 6,162E-03 0,01663519 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 6,162E-03 0,01661569 ! DNA ligation GO:0006266 14 9 0,000 6,162E-03 0,01659623 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 6,162E-03 0,01657682 ! response to amine stimulus GO:0014075 13 9 0,000 6,162E-03 0,01655746 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 6,162E-03 0,01653814 ! erythrocyte development GO:0048821 11 9 0,000 6,162E-03 0,01651886 ! renal water homeostasis GO:0003091 14 9 0,000 6,162E-03 0,01649963 ! mRNA cleavage GO:0006379 13 9 0,000 6,162E-03 0,01648045 ! hindbrain morphogenesis GO:0021575 12 9 0,000 6,162E-03 0,01646131 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 6,162E-03 0,01644221 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 6,162E-03 0,01642316 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 6,162E-03 0,01640415 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 6,162E-03 0,01638518 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 6,162E-03 0,01636626 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 6,162E-03 0,01634739 ! acid secretion GO:0046717 14 9 0,000 6,162E-03 0,01632855 ! musculoskeletal movement GO:0050881 11 9 0,000 6,162E-03 0,01630976 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 6,162E-03 0,01629102 ! methionine biosynthetic process GO:0009086 10 9 0,000 6,162E-03 0,01627231 ! purine base metabolic process GO:0006144 18 9 0,000 6,162E-03 0,01625365 ! oocyte differentiation GO:0009994 12 9 0,000 6,162E-03 0,01623503 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 6,162E-03 0,01621646 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 6,162E-03 0,01619792 ! spleen development GO:0048536 15 9 0,000 6,162E-03 0,01617943 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 6,162E-03 0,01616099 ! anterior/posterior axis specification GO:0009948 11 9 0,000 6,162E-03 0,01614258 ! regulation of RNA splicing GO:0043484 14 9 0,000 6,162E-03 0,01612421 ! detection of calcium ion GO:0005513 13 9 0,000 6,162E-03 0,01610589 ! blastocyst formation GO:0001825 12 9 0,000 6,162E-03 0,01608761 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 6,162E-03 0,01606937 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 6,162E-03 0,01605117 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 6,162E-03 0,01603301 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 6,162E-03 0,0160149 ! regulation of amino acid transport GO:0051955 11 9 0,000 6,162E-03 0,01599682 ! positive regulation of amine transport GO:0051954 15 9 0,000 6,162E-03 0,01597879 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 6,162E-03 0,01596079 ! prepulse inhibition GO:0060134 14 9 0,000 6,162E-03 0,01594284 ! embryonic placenta development GO:0001892 12 9 0,000 6,162E-03 0,01592493 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 6,162E-03 0,01590705 ! insulin secretion GO:0030073 17 9 0,000 6,162E-03 0,01588922 ! sequestering of metal ion GO:0051238 11 9 0,000 6,162E-03 0,01587143 ! response to nicotine GO:0035094 16 9 0,000 6,162E-03 0,01585367 ! establishment of cell polarity GO:0030010 12 9 0,000 6,162E-03 0,01583596 ! nucleus localization GO:0051647 15 9 0,000 6,162E-03 0,01581829 ! regulation of synapse organization GO:0050807 12 9 0,000 6,162E-03 0,01580065 ! localization within membrane GO:0051668 15 9 0,000 6,162E-03 0,01578306 ! negative regulation of muscle development GO:0048635 12 10 0,000 6,845E-03 0,01751171 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 6,845E-03 0,01749226 ! neuron fate specification GO:0048665 11 10 0,000 6,845E-03 0,01747284 ! negative regulation of blood pressure GO:0045776 22 10 0,000 6,845E-03 0,01745347 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 6,845E-03 0,01743414 ! thyroid gland development GO:0030878 19 10 0,000 6,845E-03 0,01741486 ! regulation of B cell proliferation GO:0030888 15 10 0,000 6,845E-03 0,01739561 ! synapsis GO:0007129 13 10 0,000 6,845E-03 0,01737641 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 6,845E-03 0,01735726 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 6,845E-03 0,01733814 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 6,845E-03 0,01731907 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 6,845E-03 0,01730003 ! sulfate transport GO:0008272 12 10 0,000 6,845E-03 0,01728104 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 6,845E-03 0,01726209 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 6,845E-03 0,01724319 ! androgen metabolic process GO:0008209 13 10 0,000 6,845E-03 0,01722432 ! phospholipid efflux GO:0033700 16 10 0,000 6,845E-03 0,0172055 ! hippocampus development GO:0021766 19 10 0,000 6,845E-03 0,01718671 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 6,845E-03 0,01716797 ! blood vessel remodeling GO:0001974 21 10 0,000 6,845E-03 0,01714927 ! positive regulation of heart contraction GO:0045823 14 10 0,000 6,845E-03 0,01713061 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 6,845E-03 0,01711199 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 6,845E-03 0,01709341 GO:0010812|negative regulation of cell-substrate adhesion, ! pathogenesis GO:0009405 13 10 0,000 6,845E-03 0,01707487 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 6,845E-03 0,01705637 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 6,845E-03 0,01703791 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 6,845E-03 0,01701949 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 6,845E-03 0,01700111 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 6,845E-03 0,01698277 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 6,845E-03 0,01696447 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 6,845E-03 0,01694621 ! melanocyte differentiation GO:0030318 15 10 0,000 6,845E-03 0,01692799 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 6,845E-03 0,01690981 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 6,845E-03 0,01689166 ! reverse cholesterol transport GO:0043691 16 10 0,000 6,845E-03 0,01687356 ! response to X-ray GO:0010165 16 10 0,000 6,845E-03 0,01685549 ! B cell proliferation GO:0042100 14 10 0,000 6,845E-03 0,01683747 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 6,845E-03 0,01681948 ! regulation of sodium ion transport GO:0002028 15 10 0,000 6,845E-03 0,01680153 ! forebrain cell migration GO:0021885 17 10 0,000 6,845E-03 0,01678361 ! lipid digestion GO:0044241 15 10 0,000 6,845E-03 0,01676574 ! phagocytosis, engulfment GO:0006911 20 10 0,000 6,845E-03 0,0167479 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 6,845E-03 0,01673011 ! UV protection GO:0009650 14 10 0,000 6,845E-03 0,01671235 ! entry into host cell GO:0030260 20 10 0,000 6,845E-03 0,01669462 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 6,845E-03 0,01667694 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 6,845E-03 0,01665929 ! negative regulation of ossification GO:0030279 19 10 0,000 6,845E-03 0,01664168 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 6,845E-03 0,01662411 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 6,845E-03 0,01660657 ! regulation of bone resorption GO:0045124 24 10 0,000 6,845E-03 0,01658907 ! alpha-beta T cell activation GO:0046631 16 10 0,000 6,845E-03 0,01657161 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 6,845E-03 0,01655419 ! regulation of organ growth GO:0046620 11 10 0,000 6,845E-03 0,0165368 ! response to dsRNA GO:0043331 18 10 0,000 6,845E-03 0,01651944 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 6,845E-03 0,01650213 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 6,845E-03 0,01648485 ! embryonic axis specification GO:0000578 12 10 0,000 6,845E-03 0,0164676 ! regulation of B cell differentiation GO:0045577 16 10 0,000 6,845E-03 0,0164504 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 6,845E-03 0,01643323 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 6,845E-03 0,01641609 ! cranial nerve development GO:0021545 12 10 0,000 6,845E-03 0,01639899 ! fucose catabolic process GO:0019317 16 10 0,000 6,845E-03 0,01638193 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 6,845E-03 0,0163649 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 6,845E-03 0,0163479 ! protein sumoylation GO:0016925 12 10 0,000 6,845E-03 0,01633094 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 6,845E-03 0,01631402 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 6,845E-03 0,01629713 ! zymogen activation GO:0031638 14 10 0,000 6,845E-03 0,01628028 ! salivary gland development GO:0007431 22 10 0,000 6,845E-03 0,01626346 ! negative regulation of neurological system process GO:0031645 19 10 0,000 6,845E-03 0,01624668 ! glutathione biosynthetic process GO:0006750 11 10 0,000 6,845E-03 0,01622993 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 6,845E-03 0,01621321 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 6,845E-03 0,01619653 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 6,845E-03 0,01617989 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 6,845E-03 0,01616328 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 6,845E-03 0,0161467 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 6,845E-03 0,01613015 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 6,845E-03 0,01611364 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 6,845E-03 0,01609717 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 6,845E-03 0,01608073 ! detection of bacterium GO:0016045 10 10 0,000 6,845E-03 0,01606432 ! embryonic gut development GO:0048566 11 10 0,000 6,845E-03 0,01604794 ! activation of innate immune response GO:0002218 10 10 0,000 6,845E-03 0,0160316 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 6,845E-03 0,01601529 ! developmental induction GO:0031128 13 10 0,000 6,845E-03 0,01599901 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 6,845E-03 0,01598277 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 6,845E-03 0,01596656 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 6,845E-03 0,01595039 ! negative regulation of immune effector process GO:0002698 16 10 0,000 6,845E-03 0,01593424 ! rRNA transcription GO:0009303 17 11 0,000 7,527E-03 0,01750444 ! respiratory burst GO:0045730 14 11 0,000 7,527E-03 0,01748676 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 7,527E-03 0,01746911 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 7,527E-03 0,0174515 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 7,527E-03 0,01743393 ! virus-host interaction GO:0019048 17 11 0,000 7,527E-03 0,01741639 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 7,527E-03 0,01739888 ! filopodium assembly GO:0046847 19 11 0,000 7,527E-03 0,01738141 ! Golgi vesicle budding GO:0048194 17 11 0,000 7,527E-03 0,01736398 ! RNA polyadenylation GO:0043631 19 11 0,000 7,527E-03 0,01734658 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 7,527E-03 0,01732922 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 7,527E-03 0,01731189 ! mating GO:0007618 14 11 0,000 7,527E-03 0,01729459 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 7,527E-03 0,01727733 ! T cell proliferation GO:0042098 20 11 0,000 7,527E-03 0,01726011 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 7,527E-03 0,01724292 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 7,527E-03 0,01722576 ! bone resorption GO:0045453 16 11 0,000 7,527E-03 0,01720864 ! regulated secretory pathway GO:0045055 14 11 0,000 7,527E-03 0,01719155 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 7,527E-03 0,01717449 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 7,527E-03 0,01715747 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 7,527E-03 0,01714048 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 7,527E-03 0,01712353 ! syncytium formation GO:0006949 15 11 0,000 7,527E-03 0,01710661 ! plasma membrane organization GO:0007009 18 11 0,000 7,527E-03 0,01708972 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 7,527E-03 0,01707287 ! focal adhesion formation GO:0048041 24 11 0,000 7,527E-03 0,01705605 ! mitotic spindle organization GO:0007052 15 11 0,000 7,527E-03 0,01703926 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 7,527E-03 0,01702251 ! regulation of intracellular pH GO:0051453 17 11 0,000 7,527E-03 0,01700578 ! membrane protein proteolysis GO:0033619 18 11 0,000 7,527E-03 0,0169891 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 7,527E-03 0,01697244 ! adult heart development GO:0007512 11 11 0,000 7,527E-03 0,01695582 ! chondrocyte differentiation GO:0002062 17 11 0,000 7,527E-03 0,01693923 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 7,527E-03 0,01692267 ! temperature homeostasis GO:0001659 16 11 0,000 7,527E-03 0,01690614 ! L-glutamate transport GO:0015813 16 11 0,000 7,527E-03 0,01688965 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 7,527E-03 0,01687319 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 7,527E-03 0,01685676 ! protein targeting to peroxisome GO:0006625 20 11 0,000 7,527E-03 0,01684036 ! stem cell development GO:0048864 29 11 0,000 7,527E-03 0,01682399 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 7,527E-03 0,01680766 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 7,527E-03 0,01679136 ! regulation of phagocytosis GO:0050764 14 11 0,000 7,527E-03 0,01677509 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 7,527E-03 0,01675885 ! vasoconstriction GO:0042310 15 11 0,000 7,527E-03 0,01674264 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 7,527E-03 0,01672646 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 7,527E-03 0,01671032 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 7,527E-03 0,0166942 ! ribosome assembly GO:0042255 13 11 0,000 7,527E-03 0,01667812 ! nitric oxide metabolic process GO:0046209 14 11 0,000 7,527E-03 0,01666207 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 7,527E-03 0,01664605 ! chromatin silencing GO:0006342 19 11 0,000 7,527E-03 0,01663006 ! nucleosome positioning GO:0016584 13 11 0,000 7,527E-03 0,0166141 ! T cell homeostasis GO:0043029 20 11 0,000 7,527E-03 0,01659817 ! regulation of isotype switching GO:0045191 19 11 0,000 7,527E-03 0,01658227 ! regulation of leukocyte migration GO:0002685 24 11 0,000 7,527E-03 0,0165664 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 7,527E-03 0,01655056 ! protein-chromophore linkage GO:0018298 13 11 0,000 7,527E-03 0,01653475 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 7,527E-03 0,01651898 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 7,527E-03 0,01650323 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 7,527E-03 0,01648751 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 7,527E-03 0,01647183 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 7,527E-03 0,01645617 ! male genitalia development GO:0030539 13 11 0,000 7,527E-03 0,01644054 ! cholesterol efflux GO:0033344 19 11 0,000 7,527E-03 0,01642494 ! digestive tract morphogenesis GO:0048546 15 11 0,000 7,527E-03 0,01640937 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 7,527E-03 0,01639383 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 7,527E-03 0,01637832 ! negative regulation of glucose import GO:0046325 14 11 0,000 7,527E-03 0,01636284 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 7,527E-03 0,01634739 ! regulation of organic acid transport GO:0032890 17 11 0,000 7,527E-03 0,01633197 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 7,527E-03 0,01631658 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 7,527E-03 0,01630121 ! mRNA 3'-end processing GO:0031124 19 11 0,000 7,527E-03 0,01628588 ! lysogeny GO:0030069 18 11 0,000 7,527E-03 0,01627057 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 7,527E-03 0,01625529 ! acrosome reaction GO:0007340 13 11 0,000 7,527E-03 0,01624005 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 7,527E-03 0,01622482 ! lactation GO:0007595 20 12 0,000 8,209E-03 0,01767768 ! reproductive cellular process GO:0048610 14 12 0,000 8,209E-03 0,01766114 ! tRNA modification GO:0006400 14 12 0,000 8,209E-03 0,01764463 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 8,209E-03 0,01762816 ! positive regulation of blood pressure GO:0045777 16 12 0,000 8,209E-03 0,01761171 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 8,209E-03 0,0175953 ! 'de novo' protein folding GO:0006458 18 12 0,000 8,209E-03 0,01757892 ! dicarboxylic acid transport GO:0006835 22 12 0,000 8,209E-03 0,01756257 ! non-recombinational repair GO:0000726 19 12 0,000 8,209E-03 0,01754624 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 8,209E-03 0,01752995 ! peroxisomal transport GO:0043574 21 12 0,000 8,209E-03 0,01751369 ! cartilage condensation GO:0001502 18 12 0,000 8,209E-03 0,01749746 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 8,209E-03 0,01748126 ! cytokine biosynthetic process GO:0042089 16 12 0,000 8,209E-03 0,01746509 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 8,209E-03 0,01744894 ! heart looping GO:0001947 15 12 0,000 8,209E-03 0,01743283 ! palate development GO:0060021 15 12 0,000 8,209E-03 0,01741675 ! positive regulation of cell growth GO:0030307 16 12 0,000 8,209E-03 0,0174007 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 8,209E-03 0,01738468 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 8,209E-03 0,01736868 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 8,209E-03 0,01735272 ! arginine metabolic process GO:0006525 13 12 0,000 8,209E-03 0,01733678 ! glycoprotein catabolic process GO:0006516 19 12 0,000 8,209E-03 0,01732088 ! methionine metabolic process GO:0006555 13 12 0,000 8,209E-03 0,017305 ! tyrosine metabolic process GO:0006570 14 12 0,000 8,209E-03 0,01728916 ! Golgi organization GO:0007030 18 12 0,000 8,209E-03 0,01727334 ! cell-cell junction assembly GO:0007043 18 12 0,000 8,209E-03 0,01725755 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 8,209E-03 0,01724179 ! monoamine transport GO:0015844 13 12 0,000 8,209E-03 0,01722606 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 8,209E-03 0,01721035 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 8,209E-03 0,01719468 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 8,209E-03 0,01717903 ! L-amino acid transport GO:0015807 20 12 0,000 8,209E-03 0,01716342 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 8,209E-03 0,01714783 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 8,209E-03 0,01713227 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 8,209E-03 0,01711673 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 8,209E-03 0,01710123 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 8,209E-03 0,01708575 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 8,209E-03 0,01707031 ! cerebellum development GO:0021549 13 12 0,000 8,209E-03 0,01705489 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 8,209E-03 0,01703949 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 8,209E-03 0,01702413 ! histone acetylation GO:0016573 23 12 0,000 8,209E-03 0,01700879 ! histone methylation GO:0016571 15 12 0,000 8,209E-03 0,01699348 ! autonomic nervous system development GO:0048483 23 12 0,000 8,209E-03 0,0169782 ! gland morphogenesis GO:0022612 23 12 0,000 8,209E-03 0,01696295 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 8,209E-03 0,01694772 ! peptidyl-lysine modification GO:0018205 18 12 0,000 8,209E-03 0,01693252 ! negative regulation of protein secretion GO:0050709 20 12 0,000 8,209E-03 0,01691735 ! response to gamma radiation GO:0010332 20 12 0,000 8,209E-03 0,0169022 ! regulation of epidermis development GO:0045682 17 12 0,000 8,209E-03 0,01688708 ! intestinal absorption GO:0050892 19 12 0,000 8,209E-03 0,01687199 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 8,209E-03 0,01685693 ! cAMP biosynthetic process GO:0006171 20 12 0,000 8,209E-03 0,01684189 ! regulation of mRNA stability GO:0043488 27 12 0,000 8,209E-03 0,01682688 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 8,209E-03 0,0168119 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 8,209E-03 0,01679694 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 8,209E-03 0,01678201 ! RNA 3'-end processing GO:0031123 20 12 0,000 8,209E-03 0,0167671 ! microspike assembly GO:0030035 23 12 0,000 8,209E-03 0,01675223 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 8,209E-03 0,01673737 ! response to cold GO:0009409 14 12 0,000 8,209E-03 0,01672255 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 8,89E-03 0,01809437 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 8,89E-03 0,01807837 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 8,89E-03 0,0180624 ! cGMP metabolic process GO:0046068 16 13 0,000 8,89E-03 0,01804646 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 8,89E-03 0,01803055 ! water transport GO:0006833 17 13 0,000 8,89E-03 0,01801466 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 8,89E-03 0,0179988 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 8,89E-03 0,01798297 ! lipid localization GO:0010876 24 13 0,000 8,89E-03 0,01796717 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 8,89E-03 0,0179514 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 8,89E-03 0,01793565 ! organelle fusion GO:0048284 28 13 0,000 8,89E-03 0,01791993 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 8,89E-03 0,01790424 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 8,89E-03 0,01788857 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 8,89E-03 0,01787294 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 8,89E-03 0,01785733 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 8,89E-03 0,01784175 ! response to hexose stimulus GO:0009746 19 13 0,000 8,89E-03 0,01782619 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 8,89E-03 0,01781066 ! glutamate metabolic process GO:0006536 18 13 0,000 8,89E-03 0,01779516 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 8,89E-03 0,01777969 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 8,89E-03 0,01776424 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 8,89E-03 0,01774882 ! NAD metabolic process GO:0019674 21 13 0,000 8,89E-03 0,01773343 ! exocrine system development GO:0035272 27 13 0,000 8,89E-03 0,01771806 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 8,89E-03 0,01770272 ! bone mineralization GO:0030282 15 13 0,000 8,89E-03 0,01768741 ! regulation of exocytosis GO:0017157 17 13 0,000 8,89E-03 0,01767212 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 8,89E-03 0,01765686 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 8,89E-03 0,01764162 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 8,89E-03 0,01762641 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 8,89E-03 0,01761123 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 8,89E-03 0,01759608 ! genitalia development GO:0048806 15 13 0,000 8,89E-03 0,01758095 ! regulation of cellular pH GO:0030641 20 13 0,000 8,89E-03 0,01756584 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 8,89E-03 0,01755076 ! cellular pigmentation GO:0033059 24 13 0,000 8,89E-03 0,01753571 ! tissue regeneration GO:0042246 21 13 0,000 8,89E-03 0,01752069 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 8,89E-03 0,01750569 ! cofactor transport GO:0051181 19 13 0,000 8,89E-03 0,01749071 ! NADP metabolic process GO:0006739 18 13 0,000 8,89E-03 0,01747576 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 8,89E-03 0,01746084 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 8,89E-03 0,01744594 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 8,89E-03 0,01743107 ! gas transport GO:0015669 18 13 0,000 8,89E-03 0,01741622 ! regulation of RNA stability GO:0043487 28 13 0,000 8,89E-03 0,0174014 ! heme biosynthetic process GO:0006783 20 13 0,000 8,89E-03 0,0173866 ! regulation of axon extension GO:0030516 23 13 0,000 8,89E-03 0,01737183 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 8,89E-03 0,01735708 ! lymphocyte homeostasis GO:0002260 24 13 0,000 8,89E-03 0,01734236 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 8,89E-03 0,01732766 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 8,89E-03 0,01731299 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 8,89E-03 0,01729834 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 8,89E-03 0,01728372 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 9,571E-03 0,01859167 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 9,571E-03 0,01857598 ! superoxide anion generation GO:0042554 18 14 0,000 9,571E-03 0,01856032 ! neuron maturation GO:0042551 21 14 0,000 9,571E-03 0,01854468 ! regulation of S phase GO:0033261 18 14 0,000 9,571E-03 0,01852907 ! myotube differentiation GO:0014902 21 14 0,000 9,571E-03 0,01851349 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 9,571E-03 0,01849793 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 9,571E-03 0,0184824 ! heterophilic cell adhesion GO:0007157 29 14 0,000 9,571E-03 0,01846689 ! inositol metabolic process GO:0006020 20 14 0,000 9,571E-03 0,01845141 ! aminoglycan catabolic process GO:0006026 18 14 0,000 9,571E-03 0,01843596 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 9,571E-03 0,01842053 ! retina development in camera-type eye GO:0060041 18 14 0,000 9,571E-03 0,01840513 ! cardiac muscle contraction GO:0060048 23 14 0,000 9,571E-03 0,01838976 ! gene silencing by RNA GO:0031047 20 14 0,000 9,571E-03 0,01837441 ! response to cAMP GO:0051591 19 14 0,000 9,571E-03 0,01835908 ! limbic system development GO:0021761 25 14 0,000 9,571E-03 0,01834378 ! startle response GO:0001964 21 14 0,000 9,571E-03 0,01832851 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 9,571E-03 0,01831326 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 9,571E-03 0,01829804 ! activation of MAPKK activity GO:0000186 21 14 0,000 9,571E-03 0,01828284 ! regulation of defense response to virus GO:0050688 24 14 0,000 9,571E-03 0,01826767 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 9,571E-03 0,01825252 ! epidermis morphogenesis GO:0048730 29 14 0,000 9,571E-03 0,0182374 ! glycine metabolic process GO:0006544 22 14 0,000 9,571E-03 0,0182223 ! pituitary gland development GO:0021983 23 14 0,000 9,571E-03 0,01820723 ! cellular response to starvation GO:0009267 21 14 0,000 9,571E-03 0,01819218 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 9,571E-03 0,01817716 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 9,571E-03 0,01816216 ! regulation of heart rate GO:0002027 23 14 0,000 9,571E-03 0,01814719 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 9,571E-03 0,01813224 ! negative regulation of caspase activity GO:0043154 20 14 0,000 9,571E-03 0,01811731 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 9,571E-03 0,01810242 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 9,571E-03 0,01808754 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 9,571E-03 0,01807269 ! G1/S transition checkpoint GO:0031575 33 14 0,000 9,571E-03 0,01805786 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 9,571E-03 0,01804306 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 9,571E-03 0,01802829 ! axon cargo transport GO:0008088 27 14 0,000 9,571E-03 0,01801353 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 9,571E-03 0,0179988 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 9,571E-03 0,0179841 ! DNA unwinding during replication GO:0006268 21 14 0,000 9,571E-03 0,01796942 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 9,571E-03 0,01795476 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 9,571E-03 0,01794013 ! mRNA splice site selection GO:0006376 26 14 0,000 9,571E-03 0,01792552 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 9,571E-03 0,01791093 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 9,571E-03 0,01789637 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 9,571E-03 0,01788183 ! sphingolipid catabolic process GO:0030149 23 14 0,000 9,571E-03 0,01786732 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 9,571E-03 0,01785283 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 9,571E-03 0,01783836 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 9,571E-03 0,01782392 ! muscle maintenance GO:0046716 19 14 0,000 9,571E-03 0,0178095 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 9,571E-03 0,0177951 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 9,571E-03 0,01778072 ! regulation of ATPase activity GO:0043462 18 14 0,000 9,571E-03 0,01776637 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 9,571E-03 0,01775205 ! cell killing GO:0001906 20 14 0,000 9,571E-03 0,01773774 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 9,571E-03 0,01772346 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 9,571E-03 0,0177092 ! cilium assembly GO:0042384 20 14 0,000 9,571E-03 0,01769497 ! peptide hormone secretion GO:0030072 23 14 0,000 9,571E-03 0,01768075 ! positive regulation of cell size GO:0045793 20 15 0,000 0,01025106 0,01892251 ! metencephalon development GO:0022037 19 15 0,000 0,01025106 0,01890734 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01025106 0,01889219 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01025106 0,01887706 ! skin development GO:0043588 25 15 0,000 0,01025106 0,01886196 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,01025106 0,01884688 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01025106 0,01883183 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01025106 0,0188168 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01025106 0,01880179 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01025106 0,01878681 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01025106 0,01877185 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01025106 0,01875692 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,01025106 0,01874201 ! adult walking behavior GO:0007628 25 15 0,000 0,01025106 0,01872712 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01025106 0,01871226 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01025106 0,01869742 ! myoblast differentiation GO:0045445 27 15 0,000 0,01025106 0,0186826 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01025106 0,01866781 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01025106 0,01865304 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01025106 0,0186383 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01025106 0,01862358 ! cerebral cortex development GO:0021987 29 15 0,000 0,01025106 0,01860888 ! response to osmotic stress GO:0006970 22 15 0,000 0,01025106 0,0185942 ! vesicle coating GO:0006901 25 15 0,000 0,01025106 0,01857955 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01025106 0,01856492 ! DNA integration GO:0015074 22 15 0,000 0,01025106 0,01855031 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,01025106 0,01853573 ! peptide secretion GO:0002790 27 15 0,000 0,01025106 0,01852117 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01025106 0,01850663 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01025106 0,01849212 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01025106 0,01847762 ! neuron recognition GO:0008038 22 15 0,000 0,01025106 0,01846315 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01025106 0,01844871 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01025106 0,01843428 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,01025106 0,01841988 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,01025106 0,0184055 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01025106 0,01839114 ! biomineral formation GO:0031214 18 15 0,000 0,01025106 0,01837681 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01025106 0,0183625 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01025106 0,01834821 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01025106 0,01833394 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01025106 0,01831969 ! organic cation transport GO:0015695 19 15 0,000 0,01025106 0,01830547 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01025106 0,01829127 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01025106 0,01827709 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01025106 0,01826293 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01025106 0,0182488 ! defense response to virus GO:0051607 27 15 0,000 0,01025106 0,01823468 ! peptide hormone processing GO:0016486 19 15 0,000 0,01025106 0,01822059 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01025106 0,01820652 ! protein secretion GO:0009306 27 16 0,000 0,01093103 0,01939921 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,01093103 0,01938425 ! hormone secretion GO:0046879 25 16 0,000 0,01093103 0,01936932 ! bone remodeling GO:0046849 24 16 0,000 0,01093103 0,0193544 ! endothelial cell migration GO:0043542 22 16 0,000 0,01093103 0,01933952 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,01093103 0,01932465 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01093103 0,01930981 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01093103 0,01929499 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01093103 0,01928019 ! glial cell development GO:0021782 24 16 0,000 0,01093103 0,01926542 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01093103 0,01925067 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01093103 0,01923594 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01093103 0,01922123 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01093103 0,01920655 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01093103 0,01919189 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01093103 0,01917725 ! fructose metabolic process GO:0006000 20 16 0,000 0,01093103 0,01916263 ! regulation of protein binding GO:0043393 27 16 0,000 0,01093103 0,01914804 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01093103 0,01913346 ! protein export from nucleus GO:0006611 24 16 0,000 0,01093103 0,01911891 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01093103 0,01910439 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,01093103 0,01908988 ! DNA replication initiation GO:0006270 25 16 0,000 0,01093103 0,0190754 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01093103 0,01906093 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01093103 0,01904649 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01093103 0,01903208 ! diencephalon development GO:0021536 25 16 0,000 0,01093103 0,01901768 ! oogenesis GO:0048477 23 16 0,000 0,01093103 0,0190033 ! neural crest cell migration GO:0001755 24 16 0,000 0,01093103 0,01898895 ! G1 phase GO:0051318 27 16 0,000 0,01093103 0,01897462 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01093103 0,01896031 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01093103 0,01894602 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01093103 0,01893176 ! steroid catabolic process GO:0006706 22 16 0,000 0,01093103 0,01891751 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01093103 0,01890329 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01093103 0,01888908 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,01093103 0,0188749 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01093103 0,01886074 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01093103 0,01884661 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01093103 0,01883249 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01093103 0,01881839 ! nerve development GO:0021675 18 16 0,000 0,01093103 0,01880432 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01093103 0,01879026 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01093103 0,01877623 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,01161057 0,01992859 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,01161057 0,01991373 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01161057 0,01989889 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,01161057 0,01988407 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,01161057 0,01986928 ! glycerol metabolic process GO:0006071 20 17 0,000 0,01161057 0,01985451 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,01161057 0,01983976 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,01161057 0,01982503 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01161057 0,01981032 ! signal complex assembly GO:0007172 29 17 0,000 0,01161057 0,01979563 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,01161057 0,01978097 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,01161057 0,01976633 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,01161057 0,01975171 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,01161057 0,01973711 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,01161057 0,01972253 ! memory GO:0007613 25 17 0,000 0,01161057 0,01970798 ! keratinization GO:0031424 17 17 0,000 0,01161057 0,01969345 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,01161057 0,01967893 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,01161057 0,01966444 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01161057 0,01964997 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,01161057 0,01963552 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,01161057 0,0196211 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,01161057 0,01960669 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,01161057 0,0195923 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,01161057 0,01957794 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,01161057 0,0195636 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,01161057 0,01954928 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,01161057 0,01953498 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,01161057 0,0195207 ! membrane budding GO:0006900 29 17 0,000 0,01161057 0,01950644 ! heme metabolic process GO:0042168 27 17 0,000 0,01161057 0,0194922 ! actin filament bundle formation GO:0051017 26 17 0,000 0,01161057 0,01947798 ! neuromuscular junction development GO:0007528 23 17 0,000 0,01161057 0,01946378 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,01161057 0,01944961 ! body fluid secretion GO:0007589 27 17 0,000 0,01161057 0,01943545 ! stem cell differentiation GO:0048863 36 17 0,000 0,01161057 0,01942132 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01161057 0,0194072 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,01161057 0,01939311 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,01161057 0,01937904 ! sensory perception of pain GO:0019233 23 17 0,000 0,01161057 0,01936498 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,01161057 0,01935095 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,01161057 0,01933694 ! synaptogenesis GO:0007416 24 17 0,000 0,01161057 0,01932295 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,01161057 0,01930897 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01161057 0,01929502 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,01161057 0,01928109 ! cell-cell junction organization GO:0045216 25 17 0,000 0,01161057 0,01926718 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,01161057 0,01925329 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,01161057 0,01923942 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,01161057 0,01922557 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,01161057 0,01921173 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,01161057 0,01919792 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,01161057 0,01918413 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,01228968 0,02029165 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,01228968 0,02027709 ! positive regulation of translation GO:0045727 28 18 0,000 0,01228968 0,02026256 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,01228968 0,02024804 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,01228968 0,02023355 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01228968 0,02021907 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,01228968 0,02020462 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01228968 0,02019019 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,01228968 0,02017578 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,01228968 0,02016139 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,01228968 0,02014702 ! axis specification GO:0009798 26 18 0,000 0,01228968 0,02013267 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,01228968 0,02011834 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,01228968 0,02010403 ! pancreas development GO:0031016 26 18 0,000 0,01228968 0,02008974 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,01228968 0,02007547 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,01228968 0,02006123 ! glutamine metabolic process GO:0006541 23 18 0,000 0,01228968 0,020047 ! response to retinoic acid GO:0032526 25 18 0,000 0,01228968 0,02003279 ! pigmentation during development GO:0048066 31 18 0,000 0,01228968 0,0200186 ! central nervous system neuron development GO:0021954 30 18 0,000 0,01228968 0,02000444 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,01228968 0,01999029 ! fucose metabolic process GO:0006004 26 18 0,000 0,01228968 0,01997616 ! response to fungus GO:0009620 19 18 0,000 0,01228968 0,01996205 ! peptide cross-linking GO:0018149 31 18 0,000 0,01228968 0,01994797 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,01228968 0,0199339 ! heart process GO:0003015 27 18 0,000 0,01228968 0,01991985 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,01228968 0,01990582 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,01228968 0,01989181 ! visual learning GO:0008542 35 18 0,000 0,01228968 0,01987782 ! somitogenesis GO:0001756 24 18 0,000 0,01228968 0,01986386 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,01228968 0,01984991 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,01228968 0,01983598 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,01228968 0,01982207 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,01228968 0,01980818 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,01228968 0,0197943 ! vitamin transport GO:0051180 24 18 0,000 0,01228968 0,01978045 ! hormone transport GO:0009914 27 18 0,000 0,01228968 0,01976662 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,01228968 0,01975281 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,01228968 0,01973901 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01228968 0,01972524 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,01228968 0,01971148 ! cell-cell recognition GO:0009988 20 18 0,000 0,01228968 0,01969775 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,01228968 0,01968403 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,01228968 0,01967033 ! regulation of glucose import GO:0046324 21 18 0,000 0,01228968 0,01965665 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,01228968 0,01964299 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,01228968 0,01962935 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,01228968 0,01961573 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,01228968 0,01960213 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,01296836 0,0206703 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,01296836 0,02065598 ! positive regulation of ossification GO:0045778 30 19 0,000 0,01296836 0,02064169 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,01296836 0,02062741 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,01296836 0,02061316 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,01296836 0,02059892 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,01296836 0,02058471 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,01296836 0,02057051 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,01296836 0,02055633 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,01296836 0,02054218 ! regeneration GO:0031099 32 19 0,000 0,01296836 0,02052804 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,01296836 0,02051392 ! response to alkaloid GO:0043279 32 19 0,000 0,01296836 0,02049982 ! sensory perception of taste GO:0050909 23 19 0,000 0,01296836 0,02048574 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,01296836 0,02047168 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,01296836 0,02045764 ! smooth muscle contraction GO:0006939 36 19 0,000 0,01296836 0,02044362 ! peroxisome organization GO:0007031 29 19 0,000 0,01296836 0,02042962 ! digestive system process GO:0022600 30 19 0,000 0,01296836 0,02041563 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,01296836 0,02040167 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,01296836 0,02038772 ! response to vitamin A GO:0033189 26 19 0,000 0,01296836 0,0203738 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,01296836 0,02035989 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,01296836 0,020346 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,01296836 0,02033213 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,01296836 0,02031828 ! response to starvation GO:0042594 30 19 0,000 0,01296836 0,02030445 ! sex determination GO:0007530 29 19 0,000 0,01296836 0,02029064 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,01296836 0,02027684 ! plasma membrane fusion GO:0045026 23 19 0,000 0,01296836 0,02026307 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,01296836 0,02024931 ! cytolysis GO:0019835 20 19 0,000 0,01296836 0,02023558 ! renal system process GO:0003014 35 19 0,000 0,01296836 0,02022186 ! vasodilation GO:0042311 33 19 0,000 0,01296836 0,02020816 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,01296836 0,02019447 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,01296836 0,02018081 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,01296836 0,02016717 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,01296836 0,02015354 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,01296836 0,02013993 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,01296836 0,02012634 ! sarcomere organization GO:0045214 23 19 0,000 0,01296836 0,02011277 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,01296836 0,02009922 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,01296836 0,02008568 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,01296836 0,02007217 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,01296836 0,02005867 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,01296836 0,02004519 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,01296836 0,02003172 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,01296836 0,02001828 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,01296836 0,02000485 ! protein stabilization GO:0050821 26 19 0,000 0,01296836 0,01999145 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,01364662 0,02102292 ! iron ion transport GO:0006826 37 20 0,000 0,01364662 0,02100885 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,01364662 0,0209948 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,01364662 0,02098077 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,01364662 0,02096675 ! response to vitamin GO:0033273 29 20 0,000 0,01364662 0,02095275 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,01364662 0,02093878 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,01364662 0,02092482 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,01364662 0,02091088 ! spinal cord development GO:0021510 31 20 0,000 0,01364662 0,02089695 ! response to ethanol GO:0045471 37 20 0,000 0,01364662 0,02088305 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,01364662 0,02086917 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,01364662 0,0208553 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,01364662 0,02084145 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,01364662 0,02082762 ! chromosome condensation GO:0030261 31 20 0,000 0,01364662 0,02081381 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,01364662 0,02080002 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,01364662 0,02078624 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,01364662 0,02077249 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,01364662 0,02075875 ! pallium development GO:0021543 38 20 0,000 0,01364662 0,02074503 ! DNA modification GO:0006304 28 20 0,000 0,01364662 0,02073133 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,01364662 0,02071764 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,01364662 0,02070398 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,01364662 0,02069033 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,01364662 0,0206767 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,01364662 0,02066309 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,01364662 0,02064949 ! collagen catabolic process GO:0030574 25 20 0,000 0,01364662 0,02063591 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,01364662 0,02062236 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,01364662 0,02060882 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,01364662 0,02059529 ! alditol metabolic process GO:0019400 24 20 0,000 0,01364662 0,02058179 ! actin filament-based movement GO:0030048 34 20 0,000 0,01364662 0,0205683 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,01432445 0,02157579 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,01432445 0,02156167 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,01432445 0,02154757 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,01432445 0,02153348 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,01432445 0,02151942 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,01432445 0,02150537 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,01432445 0,02149134 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,01432445 0,02147733 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,01432445 0,02146334 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,01432445 0,02144937 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,01432445 0,02143541 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,01432445 0,02142148 ! protein amino acid acylation GO:0043543 37 21 0,000 0,01432445 0,02140756 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,01432445 0,02139366 ! vesicle docking GO:0048278 27 21 0,000 0,01432445 0,02137977 ! phototransduction GO:0007602 25 21 0,000 0,01432445 0,02136591 ! dendrite development GO:0016358 35 21 0,000 0,01432445 0,02135206 ! visual behavior GO:0007632 39 21 0,000 0,01432445 0,02133823 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,01432445 0,02132442 ! ovarian follicle development GO:0001541 30 21 0,000 0,01432445 0,02131063 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,01432445 0,02129685 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,01432445 0,0212831 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,01432445 0,02126936 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,01432445 0,02125563 ! cell aging GO:0007569 32 21 0,000 0,01432445 0,02124193 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,01432445 0,02122824 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,01432445 0,02121457 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,01432445 0,02120092 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,01432445 0,02118729 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,01432445 0,02117367 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,01432445 0,02116007 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,01432445 0,02114649 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,01432445 0,02113293 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,01432445 0,02111938 ! fatty acid transport GO:0015908 30 21 0,000 0,01432445 0,02110585 ! immunoglobulin production GO:0002377 33 21 0,000 0,01432445 0,02109234 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,01432445 0,02107884 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,01432445 0,02106537 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,01432445 0,02105191 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,01432445 0,02103846 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,01432445 0,02102504 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,01432445 0,02101163 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,01432445 0,02099824 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,01432445 0,02098486 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,01432445 0,0209715 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,01432445 0,02095816 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,01432445 0,02094484 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,01432445 0,02093153 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,01432445 0,02091824 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,01432445 0,02090497 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,01432445 0,02089171 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,01500185 0,02186581 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,01500185 0,02185197 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,01500185 0,02183814 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,01500185 0,02182432 ! viral genome replication GO:0019079 29 22 0,000 0,01500185 0,02181053 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,01500185 0,02179675 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,01500185 0,02178299 ! leukocyte adhesion GO:0007159 38 22 0,000 0,01500185 0,02176925 ! molting cycle process GO:0022404 40 22 0,000 0,01500185 0,02175552 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,01500185 0,02174181 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,01500185 0,02172812 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,01500185 0,02171445 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,01500185 0,02170079 ! vasculogenesis GO:0001570 33 22 0,000 0,01500185 0,02168715 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,01500185 0,02167353 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,01500185 0,02165992 ! lysosome organization GO:0007040 37 22 0,000 0,01500185 0,02164633 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,01500185 0,02163276 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,01500185 0,02161921 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,01500185 0,02160567 ! regulation of behavior GO:0050795 38 22 0,000 0,01500185 0,02159215 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,01500185 0,02157865 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,01500185 0,02156516 ! membrane depolarization GO:0051899 35 22 0,000 0,01500185 0,02155169 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,01500185 0,02153824 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,01500185 0,0215248 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,01500185 0,02151138 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,01500185 0,02149798 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,01500185 0,02148459 ! blastocyst development GO:0001824 37 22 0,000 0,01500185 0,02147122 ! neural tube closure GO:0001843 33 22 0,000 0,01500185 0,02145787 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,01500185 0,02144453 ! protein tetramerization GO:0051262 39 22 0,000 0,01500185 0,02143121 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,01567882 0,02238442 ! neuron fate commitment GO:0048663 32 23 0,000 0,01567882 0,02237053 ! embryonic pattern specification GO:0009880 31 23 0,000 0,01567882 0,02235666 ! myelination GO:0042552 35 23 0,000 0,01567882 0,02234281 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,01567882 0,02232898 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,01567882 0,02231516 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,01567882 0,02230136 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,01567882 0,02228758 ! vesicle targeting GO:0006903 32 23 0,000 0,01567882 0,02227381 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,01567882 0,02226006 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,01567882 0,02224633 ! osteoblast differentiation GO:0001649 40 23 0,000 0,01567882 0,02223261 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,01567882 0,02221891 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,01567882 0,02220523 ! interaction with host GO:0051701 37 23 0,000 0,01567882 0,02219157 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,01567882 0,02217792 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,01567882 0,02216429 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,01567882 0,02215067 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,01567882 0,02213708 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,01567882 0,0221235 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,01567882 0,02210993 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,01567882 0,02209638 ! cell fate determination GO:0001709 45 23 0,000 0,01567882 0,02208285 ! pentose metabolic process GO:0019321 31 23 0,000 0,01567882 0,02206934 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,01567882 0,02205584 ! spermatid development GO:0007286 33 23 0,000 0,01567882 0,02204236 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,01567882 0,02202889 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,01567882 0,02201544 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,01567882 0,02200201 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,01567882 0,0219886 ! telomere organization GO:0032200 32 23 0,000 0,01567882 0,0219752 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,01567882 0,02196181 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,01567882 0,02194845 ! regulation of amine transport GO:0051952 38 23 0,000 0,01567882 0,0219351 ! liver development GO:0001889 40 23 0,000 0,01567882 0,02192176 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,01635537 0,0228538 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,01635537 0,02283993 ! initiation of viral infection GO:0019059 42 24 0,000 0,01635537 0,02282607 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,01635537 0,02281222 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,01635537 0,0227984 ! superoxide metabolic process GO:0006801 32 24 0,000 0,01635537 0,02278459 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,01635537 0,0227708 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,01635537 0,02275702 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,01635537 0,02274326 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,01635537 0,02272952 ! sperm motility GO:0030317 27 24 0,000 0,01635537 0,0227158 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,01635537 0,02270209 ! vacuole organization GO:0007033 39 24 0,000 0,01635537 0,02268839 ! receptor metabolic process GO:0043112 37 24 0,000 0,01635537 0,02267472 ! neural crest cell development GO:0014032 39 24 0,000 0,01635537 0,02266106 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,01635537 0,02264742 ! primary neural tube formation GO:0014020 35 24 0,000 0,01635537 0,02263379 ! negative regulation of cell development GO:0010721 56 24 0,000 0,01635537 0,02262018 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,01635537 0,02260659 ! base-excision repair GO:0006284 31 24 0,000 0,01635537 0,02259301 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,01635537 0,02257945 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,01635537 0,0225659 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,01635537 0,02255237 ! glutathione metabolic process GO:0006749 29 24 0,000 0,01635537 0,02253886 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,01635537 0,02252536 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,01635537 0,02251188 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,01635537 0,02249842 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,01703149 0,02341449 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,01703149 0,0234005 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,01703149 0,02338653 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,01703149 0,02337258 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,01703149 0,02335864 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,01703149 0,02334472 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,01703149 0,02333081 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 43 25 0,000 0,01703149 0,02331693 ! male gonad development GO:0008584 33 25 0,000 0,01703149 0,02330306 ! iron ion homeostasis GO:0055072 39 25 0,000 0,01703149 0,0232892 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,01703149 0,02327536 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,01703149 0,02326154 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,01703149 0,02324774 ! phospholipid transport GO:0015914 35 25 0,000 0,01703149 0,02323395 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,01703149 0,02322018 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,01703149 0,02320642 ! detection of light stimulus GO:0009583 30 25 0,000 0,01703149 0,02319268 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,01703149 0,02317896 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,01703149 0,02316525 ! leukocyte proliferation GO:0070661 39 25 0,000 0,01703149 0,02315156 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,01703149 0,02313788 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,01770719 0,02404164 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,01770719 0,02402746 ! translational initiation GO:0006413 43 26 0,000 0,01770719 0,02401329 ! regulation of pH GO:0006885 36 26 0,000 0,01770719 0,02399914 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,01770719 0,023985 ! circadian rhythm GO:0007623 42 26 0,000 0,01770719 0,02397089 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,01770719 0,02395679 ! post-embryonic development GO:0009791 42 26 0,000 0,01770719 0,0239427 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,01770719 0,02392864 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,01770719 0,02391459 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,01770719 0,02390055 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,01770719 0,02388653 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,01770719 0,02387253 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,01770719 0,02385855 ! regulation of coagulation GO:0050818 39 26 0,000 0,01770719 0,02384458 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,01838246 0,02473941 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,01838246 0,02472495 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,01838246 0,0247105 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,01838246 0,02469606 ! membrane docking GO:0022406 39 27 0,000 0,01838246 0,02468165 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,01838246 0,02466725 ! catechol metabolic process GO:0009712 43 27 0,000 0,01838246 0,02465286 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,01838246 0,0246385 ! acute-phase response GO:0006953 42 27 0,000 0,01838246 0,02462415 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,01838246 0,02460981 ! myofibril assembly GO:0030239 36 27 0,000 0,01838246 0,0245955 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,01838246 0,0245812 ! response to ionizing radiation GO:0010212 47 27 0,000 0,01838246 0,02456691 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,01838246 0,02455265 ! natural killer cell activation GO:0030101 35 27 0,000 0,01838246 0,0245384 ! lipid oxidation GO:0034440 38 27 0,000 0,01838246 0,02452416 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,01838246 0,02450995 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,01838246 0,02449575 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,01838246 0,02448156 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,01838246 0,0244674 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,01838246 0,02445324 ! gene silencing GO:0016458 41 27 0,000 0,01838246 0,02443911 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,01905731 0,02532166 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,01905731 0,02530704 ! phenol metabolic process GO:0018958 44 28 0,000 0,01905731 0,02529244 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,01905731 0,02527786 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,01905731 0,02526329 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,01905731 0,02524873 ! cell junction assembly GO:0034329 56 28 0,000 0,01905731 0,0252342 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,01905731 0,02521968 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,01905731 0,02520518 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,01905731 0,02519069 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,01905731 0,02517622 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,01905731 0,02516177 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,01905731 0,02514733 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,01905731 0,02513291 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,01905731 0,02511851 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,01905731 0,02510412 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,01905731 0,02508975 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,01905731 0,0250754 ! mesoderm formation GO:0001707 46 28 0,000 0,01905731 0,02506106 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,01905731 0,02504674 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,01905731 0,02503244 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,01905731 0,02501815 ! ensheathment of neurons GO:0007272 43 28 0,000 0,01905731 0,02500388 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,01905731 0,02498962 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,01905731 0,02497539 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,01905731 0,02496116 ! neural tube formation GO:0001841 41 28 0,000 0,01905731 0,02494696 ! placenta development GO:0001890 37 28 0,000 0,01905731 0,02493277 ! regulation of B cell activation GO:0050864 42 28 0,000 0,01905731 0,02491859 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,01973172 0,02578578 ! regulation of innate immune response GO:0045088 38 29 0,000 0,01973172 0,02577113 ! ovulation cycle process GO:0022602 41 29 0,000 0,01973172 0,02575651 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,01973172 0,0257419 ! protein targeting to membrane GO:0006612 53 29 0,000 0,01973172 0,0257273 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,01973172 0,02571273 ! mismatch repair GO:0006298 34 29 0,000 0,01973172 0,02569817 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,01973172 0,02568363 ! muscle cell development GO:0055001 38 29 0,000 0,01973172 0,0256691 ! formation of primary germ layer GO:0001704 48 29 0,000 0,01973172 0,02565459 ! telencephalon development GO:0021537 52 29 0,000 0,01973172 0,02564009 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,01973172 0,02562562 ! eye morphogenesis GO:0048592 51 29 0,000 0,01973172 0,02561115 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,01973172 0,02559671 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,02040572 0,02645612 ! collagen metabolic process GO:0032963 40 30 0,000 0,02040572 0,02644121 ! organic anion transport GO:0015711 51 30 0,000 0,02040572 0,02642632 ! cholesterol transport GO:0030301 46 30 0,000 0,02040572 0,02641145 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,02040572 0,0263966 ! spliceosome assembly GO:0000245 49 30 0,000 0,02040572 0,02638176 ! spindle organization GO:0007051 37 30 0,000 0,02040572 0,02636694 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,02040572 0,02635213 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,02040572 0,02633735 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,02040572 0,02632258 ! ceramide metabolic process GO:0006672 43 30 0,000 0,02040572 0,02630782 ! ovulation cycle GO:0042698 43 30 0,000 0,02040572 0,02629308 ! hindbrain development GO:0030902 45 30 0,000 0,02040572 0,02627836 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,02040572 0,02626366 ! adult locomotory behavior GO:0008344 47 30 0,000 0,02040572 0,02624897 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,02040572 0,02623429 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,02040572 0,02621964 ! response to heat GO:0009408 41 30 0,000 0,02040572 0,026205 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,02040572 0,02619038 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,02040572 0,02617577 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,02107929 0,02702473 ! negative regulation of secretion GO:0051048 49 31 0,000 0,02107929 0,02700967 ! mammary gland development GO:0030879 57 31 0,000 0,02107929 0,02699463 ! glial cell differentiation GO:0010001 55 31 0,000 0,02107929 0,02697961 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,02107929 0,02696461 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,02107929 0,02694962 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,02107929 0,02693465 ! odontogenesis GO:0042476 50 31 0,000 0,02107929 0,02691969 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,02107929 0,02690475 ! segmentation GO:0035282 41 31 0,000 0,02107929 0,02688983 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,02107929 0,02687492 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,02107929 0,02686003 ! metanephros development GO:0001656 58 31 0,000 0,02107929 0,02684516 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,02107929 0,02683031 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,02107929 0,02681547 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,02107929 0,02680064 ! cell fate specification GO:0001708 37 31 0,000 0,02107929 0,02678584 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,02107929 0,02677104 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,02107929 0,02675627 ! RNA modification GO:0009451 40 31 0,000 0,02107929 0,02674151 ! regulation of muscle development GO:0048634 48 32 0,000 0,02175243 0,02758026 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,02175243 0,02756507 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,02175243 0,02754989 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,02175243 0,02753472 ! meiosis I GO:0007127 52 32 0,000 0,02175243 0,02751958 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,02175243 0,02750445 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,02175243 0,02748934 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,02175243 0,02747424 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,02175243 0,02745916 ! peripheral nervous system development GO:0007422 53 32 0,000 0,02175243 0,0274441 ! regulation of protein stability GO:0031647 48 32 0,000 0,02175243 0,02742905 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,02175243 0,02741402 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,02175243 0,02739901 ! cytokine production GO:0001816 44 32 0,000 0,02175243 0,02738401 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,02175243 0,02736903 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,02175243 0,02735407 ! vesicle localization GO:0051648 47 32 0,000 0,02175243 0,02733912 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,02242515 0,02816923 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,02242515 0,02815385 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,02242515 0,02813849 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,02242515 0,02812315 ! sister chromatid segregation GO:0000819 46 33 0,000 0,02242515 0,02810782 ! ear morphogenesis GO:0042471 42 33 0,000 0,02242515 0,02809251 ! actomyosin structure organization GO:0031032 43 33 0,000 0,02242515 0,02807722 ! cell junction organization GO:0034330 63 33 0,000 0,02242515 0,02806194 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,02242515 0,02804668 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,02242515 0,02803144 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,02242515 0,02801621 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,02242515 0,02800101 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,02242515 0,02798581 ! female gonad development GO:0008585 49 33 0,000 0,02242515 0,02797064 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,02242515 0,02795548 ! positive regulation of cell development GO:0010720 54 33 0,000 0,02242515 0,02794033 ! lipid homeostasis GO:0055088 55 33 0,000 0,02242515 0,0279252 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,02242515 0,02791009 ! regulation of proteolysis GO:0030162 50 33 0,000 0,02242515 0,027895 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,02242515 0,02787992 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,02242515 0,02786486 ! cytokinesis GO:0000910 52 33 0,000 0,02242515 0,02784981 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,02242515 0,02783478 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,02309745 0,02865379 ! mRNA catabolic process GO:0006402 48 34 0,000 0,02309745 0,02863835 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,02309745 0,02862292 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,02309745 0,0286075 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,02309745 0,02859211 ! feeding behavior GO:0007631 45 34 0,000 0,02309745 0,02857673 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,02309745 0,02856136 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,02309745 0,02854601 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,02309745 0,02853068 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,02309745 0,02851537 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,02309745 0,02850007 ! neuron migration GO:0001764 46 34 0,000 0,02309745 0,02848479 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,02309745 0,02846952 ! female gamete generation GO:0007292 43 34 0,000 0,02309745 0,02845428 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,02309745 0,02843904 ! polyol metabolic process GO:0019751 44 34 0,000 0,02309745 0,02842383 ! aerobic respiration GO:0009060 47 34 0,000 0,02309745 0,02840863 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,02309745 0,02839344 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,02309745 0,02837828 ! embryonic organ development GO:0048568 45 34 0,000 0,02309745 0,02836312 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,02309745 0,02834799 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,02376932 0,02915703 ! Notch signaling pathway GO:0007219 56 35 0,000 0,02376932 0,02914149 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,02376932 0,02912597 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,02376932 0,02911046 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,02376932 0,02909497 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,02376932 0,02907949 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,02376932 0,02906403 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,02376932 0,02904859 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,02376932 0,02903316 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,02376932 0,02901775 ! glycogen metabolic process GO:0005977 48 35 0,000 0,02376932 0,02900236 ! pigment metabolic process GO:0042440 61 35 0,000 0,02376932 0,02898698 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,02376932 0,02897162 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,02376932 0,02895627 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,02444077 0,02975848 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,02444077 0,02974274 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,02444077 0,02972701 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,02444077 0,0297113 ! negative regulation of binding GO:0051100 58 36 0,000 0,02444077 0,0296956 ! organic ether metabolic process GO:0018904 46 36 0,000 0,02444077 0,02967992 ! tissue remodeling GO:0048771 62 36 0,000 0,02444077 0,02966426 ! neural tube development GO:0021915 50 36 0,000 0,02444077 0,02964861 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,02444077 0,02963298 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,02444077 0,02961737 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,02444077 0,02960178 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,02444077 0,0295862 ! glucan metabolic process GO:0044042 49 36 0,000 0,02444077 0,02957063 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,0251118 0,03036652 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,0251118 0,03035057 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,0251118 0,03033463 ! learning GO:0007612 67 37 0,000 0,0251118 0,0303187 ! ion transmembrane transport GO:0034220 56 37 0,000 0,0251118 0,0303028 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,0251118 0,03028691 ! regulation of protein secretion GO:0050708 51 37 0,000 0,0251118 0,03027103 ! amino acid activation GO:0043038 52 37 0,000 0,0251118 0,03025518 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,0251118 0,03023934 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,0257824 0,03103062 ! gliogenesis GO:0042063 71 38 0,000 0,0257824 0,03101439 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,0257824 0,03099818 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,0257824 0,03098198 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,0257824 0,0309658 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,0257824 0,03094964 ! phagocytosis GO:0006909 60 38 0,000 0,0257824 0,0309335 ! mesenchymal cell development GO:0014031 64 38 0,000 0,0257824 0,03091737 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,0257824 0,03090126 ! maintenance of location in cell GO:0051651 69 38 0,000 0,0257824 0,03088516 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,02645258 0,03167149 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,02645258 0,03165501 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,02645258 0,03163855 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,02645258 0,0316221 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,02645258 0,03160568 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,02645258 0,03158927 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,02645258 0,03157287 ! male sex differentiation GO:0046661 53 39 0,000 0,02645258 0,0315565 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,02645258 0,03154014 ! chromatin remodeling GO:0006338 68 39 0,000 0,02645258 0,0315238 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,02645258 0,03150747 ! JNK cascade GO:0007254 54 39 0,000 0,02645258 0,03149116 ! developmental growth GO:0048589 62 39 0,000 0,02645258 0,03147487 ! cell growth GO:0016049 61 39 0,000 0,02645258 0,0314586 ! synapse organization GO:0050808 55 39 0,000 0,02645258 0,03144234 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,02712233 0,03222178 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,02712233 0,03220515 ! regulation of tube size GO:0035150 60 40 0,000 0,02712233 0,03218853 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,02712233 0,03217193 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,02712233 0,03215535 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,02712233 0,03213878 ! peptide metabolic process GO:0006518 56 40 0,000 0,02712233 0,03212223 ! inner ear development GO:0048839 57 40 0,000 0,02712233 0,0321057 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,02712233 0,03208918 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,02712233 0,03207268 ! B cell differentiation GO:0030183 62 40 0,000 0,02712233 0,0320562 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,02712233 0,03203974 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,02712233 0,03202329 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,02712233 0,03200686 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,02712233 0,03199045 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,02779167 0,03276312 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,02779167 0,03274633 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,02779167 0,03272956 ! glucose transport GO:0015758 52 41 0,000 0,02779167 0,03271281 ! endosome transport GO:0016197 71 41 0,000 0,02779167 0,03269608 ! striated muscle contraction GO:0006941 62 41 0,000 0,02779167 0,03267937 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,02779167 0,03266267 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,02779167 0,03264599 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,02779167 0,03262932 ! biopolymer methylation GO:0043414 62 41 0,000 0,02779167 0,03261267 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,02779167 0,03259604 ! mitochondrial transport GO:0006839 60 42 0,000 0,02846058 0,03336358 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,02846058 0,03334658 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,02846058 0,0333296 ! cellular component disassembly GO:0022411 64 42 0,000 0,02846058 0,03331264 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,02846058 0,0332957 ! hexose transport GO:0008645 54 42 0,000 0,02846058 0,03327877 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,02846058 0,03326186 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,02846058 0,03324497 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,02846058 0,03322809 ! excretion GO:0007588 63 42 0,000 0,02846058 0,03321123 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,02846058 0,03319439 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,02846058 0,03317757 ! regulation of cell shape GO:0008360 78 42 0,000 0,02846058 0,03316076 ! positive regulation of binding GO:0051099 59 43 0,000 0,02912907 0,03392246 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,02912907 0,0339053 ! leukocyte migration GO:0050900 60 43 0,000 0,02912907 0,03388815 ! neuromuscular process GO:0050905 79 43 0,000 0,02912907 0,03387101 ! activation of caspase activity GO:0006919 65 43 0,000 0,02912907 0,0338539 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,02912907 0,0338368 ! tRNA processing GO:0008033 49 43 0,000 0,02912907 0,03381972 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,02912907 0,03380266 ! vesicle organization GO:0016050 79 43 0,000 0,02912907 0,03378561 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,02912907 0,03376858 ! methylation GO:0032259 64 43 0,000 0,02912907 0,03375157 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,02979714 0,03450827 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,02979714 0,0344909 ! glycolysis GO:0006096 53 44 0,000 0,02979714 0,03447355 ! regulation of action potential GO:0001508 71 44 0,000 0,02979714 0,03445622 ! regulation of ion transport GO:0043269 57 44 0,000 0,02979714 0,03443891 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,02979714 0,03442161 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,02979714 0,03440433 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,02979714 0,03438707 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,02979714 0,03436982 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,02979714 0,03435259 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,02979714 0,03433538 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,02979714 0,03431819 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,02979714 0,03430101 ! RNA catabolic process GO:0006401 64 45 0,000 0,03046479 0,03505203 ! positive regulation of defense response GO:0031349 59 45 0,000 0,03046479 0,03503451 ! regulation of translational initiation GO:0006446 64 45 0,000 0,03046479 0,035017 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,03046479 0,03499951 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,03046479 0,03498203 ! cell recognition GO:0008037 58 45 0,000 0,03046479 0,03496458 ! cell maturation GO:0048469 60 45 0,000 0,03046479 0,03494714 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,03046479 0,03492972 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,03113201 0,03567695 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,03113201 0,03565918 ! cell redox homeostasis GO:0045454 63 46 0,000 0,03113201 0,03564143 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,03113201 0,0356237 ! regulation of ossification GO:0030278 71 46 0,000 0,03113201 0,03560598 ! histone modification GO:0016570 68 46 0,000 0,03113201 0,03558829 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,03113201 0,03557061 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,03179882 0,03631444 ! viral infectious cycle GO:0019058 71 47 0,000 0,03179882 0,03629642 ! endocrine system development GO:0035270 83 47 0,000 0,03179882 0,03627841 ! covalent chromatin modification GO:0016569 75 47 0,000 0,03179882 0,03626043 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,03179882 0,03624246 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,03179882 0,03622451 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,03179882 0,03620658 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,03179882 0,03618866 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,03179882 0,03617076 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,03179882 0,03615288 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,03179882 0,03613502 ! chloride transport GO:0006821 67 48 0,000 0,0324652 0,03687406 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,0324652 0,03685586 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,0324652 0,03683768 ! response to temperature stimulus GO:0009266 62 48 0,000 0,0324652 0,03681951 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,0324652 0,03680136 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,0324652 0,03678324 ! gastrulation GO:0007369 73 48 0,000 0,0324652 0,03676513 ! heart morphogenesis GO:0003007 65 48 0,000 0,0324652 0,03674703 ! regulation of DNA replication GO:0006275 75 48 0,000 0,0324652 0,03672896 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,0324652 0,0367109 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,0324652 0,03669286 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,0324652 0,03667484 ! regulation of endocytosis GO:0030100 63 48 0,000 0,0324652 0,03665683 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,0324652 0,03663885 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,0324652 0,03662088 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,03313117 0,03735377 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,03313117 0,03733547 ! sensory perception of smell GO:0007608 61 49 0,000 0,03313117 0,03731718 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,03313117 0,03729892 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,03313117 0,03728067 ! RNA elongation GO:0006354 62 49 0,000 0,03313117 0,03726244 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,03313117 0,03724423 ! germ cell development GO:0007281 68 49 0,000 0,03313117 0,03722603 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,03313117 0,03720785 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,03313117 0,0371897 ! cartilage development GO:0051216 70 49 0,000 0,03313117 0,03717155 ! maintenance of location GO:0051235 84 49 0,000 0,03313117 0,03715343 ! regulation of actin filament length GO:0030832 72 50 0,000 0,03379671 0,0378813 ! ear development GO:0043583 72 50 0,000 0,03379671 0,03786285 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,03379671 0,03784442 ! membrane fusion GO:0006944 80 50 0,000 0,03379671 0,037826 ! lipid modification GO:0030258 73 50 0,000 0,03379671 0,03780761 ! positive regulation of growth GO:0045927 67 50 0,000 0,03379671 0,03778923 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,03379671 0,03777086 ! proton transport GO:0015992 75 50 0,000 0,03379671 0,03775252 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,03379671 0,03773419 ! positive regulation of secretion GO:0051047 71 51 0,000 0,03446184 0,03845814 ! hydrogen transport GO:0006818 77 51 0,000 0,03446184 0,03843949 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,03446184 0,03842085 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,03446184 0,03840224 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,03446184 0,03838364 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,03446184 0,03836506 ! adult behavior GO:0030534 80 51 0,000 0,03446184 0,0383465 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,03446184 0,03832796 ! transition metal ion transport GO:0000041 74 52 0,000 0,03512654 0,03904835 ! regulation of cellular component size GO:0032535 74 52 0,000 0,03512654 0,03902949 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,03512654 0,03901064 ! aging GO:0007568 79 52 0,000 0,03512654 0,03899182 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,03512654 0,03897301 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,03512654 0,03895421 ! establishment of organelle localization GO:0051656 85 52 0,000 0,03512654 0,03893544 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,03579082 0,03965265 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,03579082 0,03963356 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,03579082 0,03961448 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,03579082 0,03959543 ! kidney development GO:0001822 90 53 0,000 0,03579082 0,03957639 ! single fertilization GO:0007338 59 53 0,000 0,03579082 0,03955737 ! cell projection assembly GO:0030031 76 53 0,000 0,03579082 0,03953837 ! amino acid transport GO:0006865 84 54 0,000 0,03645469 0,04025242 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,03645469 0,0402331 ! regulation of mitosis GO:0007088 84 54 0,000 0,03645469 0,04021381 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,03645469 0,04019453 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,03645469 0,04017527 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,03645469 0,04015603 ! DNA catabolic process GO:0006308 67 54 0,000 0,03645469 0,04013681 ! detection of external stimulus GO:0009581 66 54 0,000 0,03645469 0,0401176 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,03645469 0,04009842 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,03645469 0,04007925 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,03645469 0,0400601 ! exocytosis GO:0006887 74 55 0,000 0,03711814 0,04076968 ! mesoderm development GO:0007498 76 55 0,000 0,03711814 0,04075022 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,03711814 0,04073078 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,03711814 0,04071136 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,03778116 0,04141882 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,03778116 0,04139908 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,03844377 0,04210508 ! carbohydrate transport GO:0008643 74 57 0,000 0,03844377 0,04208504 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,03844377 0,04206502 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,03844377 0,04204502 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,03844377 0,04202504 ! camera-type eye development GO:0043010 88 57 0,000 0,03844377 0,04200507 ! secondary metabolic process GO:0019748 84 57 0,000 0,03844377 0,04198513 ! developmental maturation GO:0021700 75 57 0,000 0,03844377 0,0419652 ! gonad development GO:0008406 79 57 0,000 0,03844377 0,04194529 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,03910596 0,04264757 ! viral reproductive process GO:0022415 87 58 0,000 0,03910596 0,04262735 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,03910596 0,04260716 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,03910596 0,04258699 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,03976774 0,04328717 ! activation of MAPK activity GO:0000187 84 59 0,000 0,03976774 0,0432667 ! lung development GO:0030324 94 59 0,000 0,03976774 0,04324624 ! actin filament organization GO:0007015 95 59 0,000 0,03976774 0,0432258 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,03976774 0,04320538 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,03976774 0,04318498 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,04042909 0,04388245 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,04042909 0,04386175 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,04042909 0,04384107 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,04042909 0,04382041 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,04042909 0,04379977 ! regulation of heart contraction GO:0008016 91 60 0,000 0,04042909 0,04377915 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,04042909 0,04375855 ! fertilization GO:0009566 68 60 0,000 0,04042909 0,04373796 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,04042909 0,0437174 ! meiosis GO:0007126 96 61 0,000 0,04109003 0,04441122 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,04109003 0,04439036 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,04109003 0,04436951 ! urogenital system development GO:0001655 101 61 0,000 0,04109003 0,04434869 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,04109003 0,04432789 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,04109003 0,04430711 ! extracellular matrix organization GO:0030198 103 61 0,000 0,04109003 0,04428635 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,04109003 0,0442656 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,04109003 0,04424488 ! amine catabolic process GO:0009310 90 62 0,000 0,04175055 0,04493508 ! neurotransmitter transport GO:0006836 81 62 0,000 0,04175055 0,04491406 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,04175055 0,04489306 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,04175055 0,04487209 ! respiratory tube development GO:0030323 99 62 0,000 0,04175055 0,04485113 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,04175055 0,04483019 ! meiotic cell cycle GO:0051321 97 62 0,000 0,04175055 0,04480927 ! organelle localization GO:0051640 96 62 0,000 0,04175055 0,04478837 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,04241065 0,04547529 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,04241065 0,0454541 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,04241065 0,04543293 ! viral reproduction GO:0016032 92 63 0,000 0,04241065 0,04541178 ! regulation of lipase activity GO:0060191 109 63 0,000 0,04241065 0,04539065 ! negative regulation of cell size GO:0045792 108 64 0,000 0,04307034 0,04607525 ! appendage morphogenesis GO:0035107 93 64 0,000 0,04307034 0,04605382 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,04307034 0,04603242 ! hexose catabolic process GO:0019320 82 64 0,000 0,04307034 0,04601104 ! respiratory system development GO:0060541 100 64 0,000 0,04307034 0,04598968 ! adaptive immune response GO:0002250 94 64 0,000 0,04307034 0,04596834 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,04372961 0,04665032 ! regulation of caspase activity GO:0043281 97 65 0,000 0,04372961 0,0466287 ! appendage development GO:0048736 94 65 0,000 0,04372961 0,04660709 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,04372961 0,0465855 ! defense response to bacterium GO:0042742 73 65 0,000 0,04372961 0,04656393 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,04372961 0,04654239 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,04372961 0,04652086 ! activation of immune response GO:0002253 83 65 0,000 0,04372961 0,04649935 ! protein oligomerization GO:0051259 100 65 0,000 0,04372961 0,04647786 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,04438846 0,04715633 ! antigen processing and presentation GO:0019882 96 66 0,000 0,04438846 0,04713456 ! axon guidance GO:0007411 99 66 0,000 0,04438846 0,04711281 ! regulation of immune effector process GO:0002697 101 66 0,000 0,04438846 0,04709108 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,0450469 0,04776757 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,0450469 0,04774556 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,0450469 0,04772357 ! acute inflammatory response GO:0002526 92 68 0,000 0,04570492 0,04839839 ! learning or memory GO:0007611 123 68 0,000 0,04570492 0,04837612 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,04570492 0,04835387 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,04570492 0,04833164 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,04570492 0,04830943 ! rhythmic process GO:0048511 105 68 0,000 0,04570492 0,04828724 ! inorganic anion transport GO:0015698 93 68 0,000 0,04570492 0,04826507 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,04636252 0,04893704 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,04636252 0,04891459 ! response to drug GO:0042493 108 69 0,000 0,04636252 0,04889216 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,04701971 0,04956249 ! humoral immune response GO:0006959 86 70 0,000 0,04701971 0,04953978 ! eye development GO:0001654 111 70 0,000 0,04701971 0,0495171 ! amine transport GO:0015837 101 70 0,000 0,04701971 0,04949444 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,04701971 0,04947179 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,04767649 0,05013988 ! muscle cell differentiation GO:0042692 104 71 0,000 0,04767649 0,05011697 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,04767649 0,05009407 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,04767649 0,0500712 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,04767649 0,05004835 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,04767649 0,05002551 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,04833285 0,05069109 ! response to hypoxia GO:0001666 132 72 0,000 0,04833285 0,05066798 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,04833285 0,0506449 ! regulation of blood pressure GO:0008217 107 73 0,000 0,04898879 0,05130885 ! tube morphogenesis GO:0035239 118 73 0,000 0,04898879 0,05128549 ! mitochondrion organization GO:0007005 104 73 0,000 0,04898879 0,05126216 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,04898879 0,05123885 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,04964432 0,05190088 ! response to oxygen levels GO:0070482 137 74 0,000 0,04964432 0,0518773 ! digestion GO:0007586 97 74 0,000 0,04964432 0,05185375 ! protein import into nucleus GO:0006606 118 74 0,000 0,04964432 0,05183021 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,04964432 0,05180669 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,04964432 0,0517832 ! blood coagulation GO:0007596 116 75 0,000 0,05029944 0,05244275 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,05029944 0,05241899 ! response to nutrient GO:0007584 104 75 0,000 0,05029944 0,05239525 ! nuclear import GO:0051170 121 75 0,000 0,05029944 0,05237153 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,05029944 0,05234783 ! amine biosynthetic process GO:0009309 97 76 0,000 0,05095414 0,05300522 ! tRNA metabolic process GO:0006399 95 76 0,000 0,05095414 0,05298125 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,05095414 0,05295731 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,05160843 0,0536131 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,05160843 0,05358889 ! regulation of DNA binding GO:0051101 119 77 0,000 0,05160843 0,05356471 ! gland development GO:0048732 148 77 0,000 0,05160843 0,05354055 ! sex differentiation GO:0007548 105 77 0,000 0,05160843 0,05351641 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,05160843 0,05349229 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,05160843 0,0534682 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,05160843 0,05344412 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,05226231 0,0540969 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,05226231 0,05407256 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,05291577 0,05472404 ! cellular respiration GO:0045333 107 79 0,000 0,05291577 0,05469945 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,05291577 0,05467487 ! T cell activation GO:0042110 134 79 0,000 0,05291577 0,05465032 ! regulation of lyase activity GO:0051339 133 79 0,000 0,05291577 0,05462579 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,05291577 0,05460129 ! chromatin assembly GO:0031497 102 80 0,000 0,05356882 0,05525035 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,05356882 0,05522559 ! protein localization in nucleus GO:0034504 133 80 0,000 0,05356882 0,05520084 ! forebrain development GO:0030900 131 80 0,000 0,05356882 0,05517612 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,05422145 0,05582334 ! hemostasis GO:0007599 125 81 0,000 0,05422145 0,05579837 ! mRNA transport GO:0051028 121 81 0,000 0,05422145 0,05577341 ! regulation of neurological system process GO:0031644 122 81 0,000 0,05422145 0,05574848 ! vitamin metabolic process GO:0006766 103 81 0,000 0,05422145 0,05572357 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,05422145 0,05569868 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,05487368 0,05634351 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,05487368 0,05631837 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,05552549 0,05696192 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,05552549 0,05693653 ! regulation of defense response GO:0031347 117 84 0,000 0,05617689 0,05757881 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,05617689 0,05755316 ! sterol metabolic process GO:0016125 120 84 0,000 0,05617689 0,05752754 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,05682788 0,05816828 ! rRNA metabolic process GO:0016072 107 85 0,000 0,05682788 0,0581424 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,05682788 0,05811655 ! transcription initiation GO:0006352 118 85 0,000 0,05682788 0,05809072 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,05682788 0,05806491 ! regulation of membrane potential GO:0042391 128 85 0,000 0,05682788 0,05803913 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,05682788 0,05801337 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,05747845 0,05865148 ! nucleosome organization GO:0034728 114 87 0,000 0,05812862 0,05928861 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,05812862 0,05926233 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,05812862 0,05923607 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,05812862 0,05920984 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,05812862 0,05918363 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,05812862 0,05915744 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,05877837 0,05979224 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,05877837 0,0597658 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,05877837 0,05973939 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,05942771 0,06037268 ! reproductive developmental process GO:0003006 127 89 0,000 0,05942771 0,06034602 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,05942771 0,06031939 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,05942771 0,06029278 ! regulation of T cell activation GO:0050863 128 89 0,000 0,05942771 0,0602662 ! leukocyte differentiation GO:0002521 143 90 0,000 0,06007664 0,06089743 ! hormone metabolic process GO:0042445 121 90 0,000 0,06007664 0,06087061 ! ATP metabolic process GO:0046034 137 91 0,000 0,06072516 0,06150061 ! response to virus GO:0009615 122 91 0,000 0,06072516 0,06147354 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,06137328 0,0621023 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,06137328 0,06207499 ! cell fate commitment GO:0045165 141 92 0,000 0,06137328 0,06204771 ! positive regulation of immune response GO:0050778 121 92 0,000 0,06137328 0,06202045 ! sulfur metabolic process GO:0006790 118 92 0,000 0,06137328 0,06199321 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,06202098 0,06261995 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,06202098 0,06259247 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,06202098 0,06256502 ! electron transport chain GO:0022900 123 94 0,000 0,06266827 0,06319027 ! response to oxidative stress GO:0006979 141 94 0,000 0,06266827 0,06316258 ! regulation of binding GO:0051098 151 95 0,000 0,06331515 0,06378662 ! angiogenesis GO:0001525 149 95 0,000 0,06331515 0,06375869 ! carboxylic acid transport GO:0046942 147 95 0,000 0,06331515 0,06373079 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,06396162 0,06435334 ! in utero embryonic development GO:0001701 147 96 0,000 0,06396162 0,0643252 ! protein maturation GO:0051604 129 96 0,000 0,06396162 0,06429709 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,06460769 0,06491816 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,06460769 0,06488982 ! calcium ion transport GO:0006816 167 99 0,000 0,06589859 0,06615746 ! extracellular structure organization GO:0043062 156 99 0,000 0,06589859 0,0661286 ! protein import GO:0017038 156 99 0,000 0,06589859 0,06609976 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,06654342 0,06671747 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,06654342 0,0666884 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,06654342 0,06665935 ! divalent metal ion transport GO:0070838 171 100 0,000 0,06654342 0,06663033 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,06654342 0,06660134 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,06654342 0,06657237 ! protein localization in organelle GO:0033365 161 100 0,000 0,06654342 0,06654342