Study run-a2
Study informations
103 subnetworks in total page | file
306 genes associated page | file
Enriched GO terms page
General informations
General Index page
Study Index page
Subnetwork 5909-7-real
score
| Dataset | Score | P-val 1 | P-val 2 | P-val 3 |
|---|
| Desmedt | 0.1998 | 1.399e-02 | 1.096e-02 | 1.136e-01 |
|---|
| IPC-NIBC-129 | 0.2874 | 4.667e-02 | 6.738e-02 | 4.260e-01 |
|---|
| Ivshina_GPL96-GPL97 | 0.2335 | 1.095e-02 | 1.807e-02 | 2.862e-01 |
|---|
| Loi_GPL570 | 0.2276 | 8.016e-02 | 9.003e-02 | 3.142e-01 |
|---|
| Loi_GPL96-GPL97 | 0.1631 | 0.000e+00 | 3.000e-06 | 0.000e+00 |
|---|
| Parker_GPL1390 | 0.2356 | 5.869e-02 | 7.236e-02 | 4.295e-01 |
|---|
| Parker_GPL887 | 0.1533 | 3.600e-01 | 3.788e-01 | 3.926e-01 |
|---|
| Pawitan_GPL96-GPL97 | 0.3690 | 3.296e-01 | 2.584e-01 | 8.898e-01 |
|---|
| Schmidt | 0.2318 | 2.683e-02 | 3.164e-02 | 2.842e-01 |
|---|
| Sotiriou | 0.3126 | 1.205e-02 | 9.267e-03 | 2.094e-01 |
|---|
| Van-De-Vijver | 0.2620 | 9.070e-04 | 1.305e-03 | 5.496e-02 |
|---|
| Zhang | 0.2528 | 1.281e-01 | 8.306e-02 | 2.702e-01 |
|---|
| Zhou | 0.4258 | 6.124e-02 | 4.930e-02 | 3.683e-01 |
|---|
Expression data for subnetwork 5909-7-real in each dataset
Desmedt |
IPC-NIBC-129 |
Ivshina_GPL96-GPL97 |
Loi_GPL570 |
Loi_GPL96-GPL97 |
Parker_GPL1390 |
Parker_GPL887 |
Pawitan_GPL96-GPL97 |
Schmidt |
Sotiriou |
Van-De-Vijver |
Zhang |
Zhou |
Subnetwork structure for each dataset
- Desmedt
Score for each gene in subnetwork 5909-7-real in each dataset
| Gene Symbol | Links | Frequency | Frequency Rank | Subnetwork score rank | Global rank |
Desmedt | IPC-NIBC-129 | Ivshina_GPL96-GPL97 | Loi_GPL570 | Loi_GPL96-GPL97 | Parker_GPL1390 | Parker_GPL887 | Pawitan_GPL96-GPL97 | Schmidt | Sotiriou | Van-De-Vijver | Zhang | Zhou |
|---|
| rap1gap |   | 1 | 116 | 139 | 144 | 0.019 | 0.060 | 0.005 | 0.138 | 0.092 | 0.049 | 0.059 | 0.094 | 0.015 | -0.030 | 0.010 | 0.009 | 0.072 |
|---|
| mybl2 | | 9 | 22 | 56 | 48 | 0.162 | 0.237 | 0.166 | 0.079 | 0.124 | 0.184 | 0.333 | 0.275 | 0.202 | 0.182 | 0.289 | 0.074 | 0.245 |
|---|
| cdkn1a | | 44 | 7 | 1 | 4 | 0.115 | -0.020 | 0.065 | 0.082 | 0.099 | 0.124 | 0.055 | 0.087 | 0.068 | 0.144 | undef | -0.201 | 0.069 |
|---|
| tle1 | | 47 | 6 | 1 | 3 | 0.062 | 0.235 | -0.032 | -0.177 | 0.033 | 0.085 | 0.339 | 0.068 | 0.126 | -0.027 | 0.170 | 0.068 | 0.025 |
|---|
| ccnb1 | | 42 | 8 | 56 | 39 | 0.082 | 0.246 | 0.212 | 0.224 | 0.256 | 0.099 | 0.126 | 0.351 | 0.129 | 0.249 | undef | 0.167 | 0.398 |
|---|
| ccnd1 | | 92 | 2 | 18 | 12 | 0.127 | -0.183 | 0.062 | 0.190 | 0.157 | -0.002 | -0.190 | 0.105 | -0.107 | 0.174 | undef | 0.144 | 0.290 |
|---|
| tsc1 | | 58 | 4 | 18 | 13 | 0.049 | 0.012 | -0.055 | 0.072 | 0.055 | -0.144 | -0.242 | -0.196 | 0.006 | 0.010 | 0.095 | -0.007 | 0.207 |
|---|
| cks2 | | 12 | 18 | 34 | 32 | 0.050 | 0.233 | 0.170 | 0.103 | 0.186 | 0.172 | 0.093 | 0.167 | 0.263 | 0.151 | 0.080 | 0.284 | 0.383 |
|---|
| cdc2 | | 96 | 1 | 1 | 1 | 0.073 | 0.247 | 0.206 | 0.172 | 0.247 | 0.153 | -0.131 | 0.282 | 0.226 | 0.221 | 0.162 | 0.297 | 0.336 |
|---|
| sfn | | 61 | 3 | 1 | 2 | 0.077 | 0.137 | 0.111 | 0.172 | 0.112 | 0.119 | 0.141 | 0.219 | 0.100 | 0.147 | 0.158 | 0.079 | 0.181 |
|---|
GO Enrichment output for subnetwork 5909-7-real in each dataset
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 |  | 7.365E-10 | 1.694E-06 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 8.282E-07 | 9.524E-04 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 9.496E-07 | 7.28E-04 |
|---|
| interphase | GO:0051325 | | 1.042E-06 | 5.989E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 6.087E-06 | 2.8E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 7.591E-06 | 2.91E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 7.841E-06 | 2.576E-03 |
|---|
| positive regulation of Rho GTPase activity | GO:0032321 | | 7.841E-06 | 2.254E-03 |
|---|
| response to UV | GO:0009411 | | 9.322E-06 | 2.382E-03 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 1.645E-05 | 3.783E-03 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 1.645E-05 | 3.439E-03 |
|---|
IPC-NIBC-129 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.013E-10 | 2.474E-07 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 2.04E-07 | 2.492E-04 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 2.956E-07 | 2.407E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 1.811E-06 | 1.106E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 1.937E-06 | 9.465E-04 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 2.705E-06 | 1.101E-03 |
|---|
| response to UV | GO:0009411 | | 3.338E-06 | 1.165E-03 |
|---|
| activation of Ras GTPase activity | GO:0032856 | | 4.055E-06 | 1.238E-03 |
|---|
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 | | 6.348E-06 | 1.723E-03 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 6.635E-06 | 1.621E-03 |
|---|
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 | | 6.635E-06 | 1.473E-03 |
|---|
Ivshina_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 2.312E-10 | 5.562E-07 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 3.472E-07 | 4.177E-04 |
|---|
| interphase | GO:0051325 | | 3.935E-07 | 3.156E-04 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 4.853E-07 | 2.919E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 2.97E-06 | 1.429E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 3.176E-06 | 1.274E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 3.766E-06 | 1.295E-03 |
|---|
| activation of Ras GTPase activity | GO:0032856 | | 3.766E-06 | 1.133E-03 |
|---|
| response to UV | GO:0009411 | | 4.888E-06 | 1.307E-03 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 9.94E-06 | 2.392E-03 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 1.039E-05 | 2.274E-03 |
|---|
Loi_GPL570 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.013E-10 | 2.474E-07 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 2.04E-07 | 2.492E-04 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 2.956E-07 | 2.407E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 1.811E-06 | 1.106E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 1.937E-06 | 9.465E-04 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 2.705E-06 | 1.101E-03 |
|---|
| response to UV | GO:0009411 | | 3.338E-06 | 1.165E-03 |
|---|
| activation of Ras GTPase activity | GO:0032856 | | 4.055E-06 | 1.238E-03 |
|---|
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 | | 6.348E-06 | 1.723E-03 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 6.635E-06 | 1.621E-03 |
|---|
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 | | 6.635E-06 | 1.473E-03 |
|---|
Loi_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 2.312E-10 | 5.562E-07 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 3.472E-07 | 4.177E-04 |
|---|
| interphase | GO:0051325 | | 3.935E-07 | 3.156E-04 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 4.853E-07 | 2.919E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 2.97E-06 | 1.429E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 3.176E-06 | 1.274E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 3.766E-06 | 1.295E-03 |
|---|
| activation of Ras GTPase activity | GO:0032856 | | 3.766E-06 | 1.133E-03 |
|---|
| response to UV | GO:0009411 | | 4.888E-06 | 1.307E-03 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 9.94E-06 | 2.392E-03 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 1.039E-05 | 2.274E-03 |
|---|
Parker_GPL1390 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| cyclin-dependent protein kinase regulator activity | GO:0016538 | | 2.114E-11 | 7.55E-08 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 4.57E-11 | 8.159E-08 |
|---|
| protein kinase regulator activity | GO:0019887 | | 1.639E-10 | 1.951E-07 |
|---|
| kinase regulator activity | GO:0019207 | | 4.235E-10 | 3.781E-07 |
|---|
| cyclin-dependent protein kinase holoenzyme complex | GO:0000307 | | 8.812E-09 | 6.294E-06 |
|---|
| protein serine/threonine kinase inhibitor activity | GO:0030291 | | 5.717E-08 | 3.403E-05 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 1.067E-07 | 5.444E-05 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 1.099E-07 | 4.906E-05 |
|---|
| protein kinase inhibitor activity | GO:0004860 | | 5.124E-07 | 2.033E-04 |
|---|
| kinase inhibitor activity | GO:0019210 | | 6.346E-07 | 2.266E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 1.921E-06 | 6.237E-04 |
|---|
Parker_GPL887 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 3.06E-11 | 1.116E-07 |
|---|
| cyclin-dependent protein kinase regulator activity | GO:0016538 | | 4.099E-11 | 7.476E-08 |
|---|
| protein kinase regulator activity | GO:0019887 | | 1.16E-10 | 1.411E-07 |
|---|
| kinase regulator activity | GO:0019207 | | 2.393E-10 | 2.183E-07 |
|---|
| cyclin-dependent protein kinase holoenzyme complex | GO:0000307 | | 6.139E-09 | 4.479E-06 |
|---|
| protein serine/threonine kinase inhibitor activity | GO:0030291 | | 6.125E-08 | 3.724E-05 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 6.125E-08 | 3.192E-05 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 6.696E-08 | 3.054E-05 |
|---|
| interphase | GO:0051325 | | 7.392E-08 | 2.996E-05 |
|---|
| protein kinase inhibitor activity | GO:0004860 | | 6.512E-07 | 2.375E-04 |
|---|
| kinase inhibitor activity | GO:0019210 | | 7.12E-07 | 2.361E-04 |
|---|
Pawitan_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 2.312E-10 | 5.562E-07 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 3.472E-07 | 4.177E-04 |
|---|
| interphase | GO:0051325 | | 3.935E-07 | 3.156E-04 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 4.853E-07 | 2.919E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 2.97E-06 | 1.429E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 3.176E-06 | 1.274E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 3.766E-06 | 1.295E-03 |
|---|
| activation of Ras GTPase activity | GO:0032856 | | 3.766E-06 | 1.133E-03 |
|---|
| response to UV | GO:0009411 | | 4.888E-06 | 1.307E-03 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 9.94E-06 | 2.392E-03 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 1.039E-05 | 2.274E-03 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 7.365E-10 | 1.694E-06 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 8.282E-07 | 9.524E-04 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 9.496E-07 | 7.28E-04 |
|---|
| interphase | GO:0051325 | | 1.042E-06 | 5.989E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 6.087E-06 | 2.8E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 7.591E-06 | 2.91E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 7.841E-06 | 2.576E-03 |
|---|
| positive regulation of Rho GTPase activity | GO:0032321 | | 7.841E-06 | 2.254E-03 |
|---|
| response to UV | GO:0009411 | | 9.322E-06 | 2.382E-03 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 1.645E-05 | 3.783E-03 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 1.645E-05 | 3.439E-03 |
|---|
Sotiriou file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 7.365E-10 | 1.694E-06 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 8.282E-07 | 9.524E-04 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 9.496E-07 | 7.28E-04 |
|---|
| interphase | GO:0051325 | | 1.042E-06 | 5.989E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 6.087E-06 | 2.8E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 7.591E-06 | 2.91E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 7.841E-06 | 2.576E-03 |
|---|
| positive regulation of Rho GTPase activity | GO:0032321 | | 7.841E-06 | 2.254E-03 |
|---|
| response to UV | GO:0009411 | | 9.322E-06 | 2.382E-03 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 1.645E-05 | 3.783E-03 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 1.645E-05 | 3.439E-03 |
|---|
Van-De-Vijver file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 2.388E-06 | 4.4E-03 |
|---|
| positive regulation of cell growth | GO:0030307 | | 9.493E-06 | 8.748E-03 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 9.493E-06 | 5.832E-03 |
|---|
| regulation of Rho GTPase activity | GO:0032319 | | 9.493E-06 | 4.374E-03 |
|---|
| positive regulation of Ras GTPase activity | GO:0032320 | | 9.493E-06 | 3.499E-03 |
|---|
| positive regulation of GTPase activity | GO:0043547 | | 1.329E-05 | 4.081E-03 |
|---|
| keratinocyte proliferation | GO:0043616 | | 1.329E-05 | 3.498E-03 |
|---|
| regulation of stress fiber formation | GO:0051492 | | 1.771E-05 | 4.079E-03 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 1.771E-05 | 3.626E-03 |
|---|
| negative regulation of signal transduction | GO:0009968 | | 2.06E-05 | 3.797E-03 |
|---|
| positive regulation of cell size | GO:0045793 | | 2.276E-05 | 3.813E-03 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 7.365E-10 | 1.694E-06 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 8.282E-07 | 9.524E-04 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 9.496E-07 | 7.28E-04 |
|---|
| interphase | GO:0051325 | | 1.042E-06 | 5.989E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 6.087E-06 | 2.8E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 7.591E-06 | 2.91E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 7.841E-06 | 2.576E-03 |
|---|
| positive regulation of Rho GTPase activity | GO:0032321 | | 7.841E-06 | 2.254E-03 |
|---|
| response to UV | GO:0009411 | | 9.322E-06 | 2.382E-03 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 1.645E-05 | 3.783E-03 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 1.645E-05 | 3.439E-03 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.252E-09 | 2.971E-06 |
|---|
| G2/M transition of mitotic cell cycle | GO:0000086 | | 9.725E-07 | 1.154E-03 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 1.259E-06 | 9.96E-04 |
|---|
| interphase | GO:0051325 | | 1.38E-06 | 8.184E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 8.289E-06 | 3.934E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 8.632E-06 | 3.414E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 9.551E-06 | 3.238E-03 |
|---|
| response to UV | GO:0009411 | | 1.167E-05 | 3.462E-03 |
|---|
| positive regulation of Rho GTPase activity | GO:0032321 | | 1.294E-05 | 3.412E-03 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 1.811E-05 | 4.297E-03 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 2.413E-05 | 5.205E-03 |
|---|
