pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/9643-11-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 4,000 3,593E-09 8,527E-06 ! thymus development GO:0048538 19 11 2,000 2,216E-07 2,629E-04 ! positive regulation of fibroblast proliferation GO:0048146 30 21 2,000 1,773E-06 1,402E-03 ! regulation of fibroblast proliferation GO:0048145 39 25 2,000 3,056E-06 1,813E-03 ! induction of apoptosis by intracellular signals GO:0008629 78 42 2,000 1,506E-05 7,147E-03 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 2,000 1,735E-05 6,861E-03 ! response to UV GO:0009411 79 47 2,000 2,119E-05 7,184E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,677E-05 7,941E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 3,567E-05 9,405E-03 ! keratinocyte proliferation GO:0043616 15 8 1,000 3,567E-05 8,465E-03 ! induction of an organ GO:0001759 13 9 1,000 4,583E-05 9,887E-03 ! negative regulation of protein kinase activity GO:0006469 110 62 2,000 4,887E-05 9,664E-03 ! negative regulation of kinase activity GO:0033673 112 63 2,000 5,128E-05 9,36E-03 ! positive regulation of B cell proliferation GO:0030890 14 10 1,000 5,725E-05 9,703E-03 ! negative regulation of transferase activity GO:0051348 117 66 2,000 5,895E-05 9,326E-03 ! thyroid gland development GO:0030878 20 11 1,000 6,992E-05 0,01036999 ! T cell homeostasis GO:0043029 22 12 1,000 8,384E-05 0,01170375 ! male genitalia development GO:0030539 15 12 1,000 8,384E-05 0,01105354 ! developmental induction GO:0031128 16 12 1,000 8,384E-05 0,01047178 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of B cell proliferation GO:0030888 24 13 1,000 9,902E-05 0,01174868 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 1,000 9,902E-05 0,01118921 ! negative regulation of microtubule depolymerization GO:0007026 34 14 1,000 1,154E-04 0,01245195 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,154E-04 0,01191056 ! genitalia development GO:0048806 18 14 1,000 1,154E-04 0,01141429 ! skin development GO:0043588 28 15 1,000 1,331E-04 0,01263462 ! lymphocyte homeostasis GO:0002260 29 15 1,000 1,331E-04 0,01214867 ! release of cytochrome c from mitochondria GO:0001836 29 15 1,000 1,331E-04 0,01169872 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 1,000 1,331E-04 0,01128091 ! interphase of mitotic cell cycle GO:0051329 166 87 2,000 1,344E-04 0,01099841 ! interphase GO:0051325 169 89 2,000 1,438E-04 0,01137384 ! positive regulation of cell growth GO:0030307 22 16 1,000 1,52E-04 0,01163662 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 1,000 1,52E-04 0,01127298 GO:0060675|ureteric bud morphogenesis, ! negative regulation of peptidase activity GO:0010466 25 17 1,000 1,722E-04 0,01238017 ! cellular response to unfolded protein GO:0034620 24 18 1,000 1,935E-04 0,01350854 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of cell size GO:0045793 26 19 1,000 2,162E-04 0,0146561 ! positive regulation of DNA replication GO:0045740 37 21 1,000 2,651E-04 0,01747415 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 1,000 2,651E-04 0,01700187 ! apoptotic mitochondrial changes GO:0008637 42 21 1,000 2,651E-04 0,01655446 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 1,000 2,651E-04 0,01612998 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 1,000 2,651E-04 0,01572673 ! cellular response to extracellular stimulus GO:0031668 37 23 1,000 3,189E-04 0,01845886 ! positive regulation of B cell activation GO:0050871 36 23 1,000 3,189E-04 0,01801936 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 1,000 3,477E-04 0,01918683 ! response to endoplasmic reticulum stress GO:0034976 32 24 1,000 3,477E-04 0,01875077 ! ureteric bud development GO:0001657 35 25 1,000 3,776E-04 0,01991434 ! negative regulation of phosphorylation GO:0042326 46 25 1,000 3,776E-04 0,01948142 ! leukocyte homeostasis GO:0001776 40 25 1,000 3,776E-04 0,01906692 ! odontogenesis of dentine-containing tooth GO:0042475 43 26 1,000 4,088E-04 0,02021127 ! ER-nuclear signaling pathway GO:0006984 33 26 1,000 4,088E-04 0,0197988 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 1,000 4,088E-04 0,01940282 ! fat cell differentiation GO:0045444 41 27 1,000 4,412E-04 0,02052972 ! negative regulation of phosphorus metabolic process GO:0010563 51 27 1,000 4,412E-04 0,02013492 GO:0045936|negative regulation of phosphate metabolic process, ! peptidyl-tyrosine modification GO:0018212 44 28 1,000 4,748E-04 0,02125967 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 1,000 5,096E-04 0,02239584 ! inner ear morphogenesis GO:0042472 43 31 1,000 5,829E-04 0,02514864 ! spindle organization GO:0007051 39 33 1,000 6,609E-04 0,02800654 ! regulation of microtubule-based process GO:0032886 66 33 1,000 6,609E-04 0,02751519 ! regulation of B cell activation GO:0050864 55 33 1,000 6,609E-04 0,02704079 ! embryonic skeletal system morphogenesis GO:0048704 49 34 1,000 7,017E-04 0,02822403 ! cell fate specification GO:0001708 49 34 1,000 7,017E-04 0,02775363 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 1,000 7,017E-04 0,02729865 ! metanephros development GO:0001656 61 35 1,000 7,437E-04 0,02846611 ! negative regulation of hydrolase activity GO:0051346 56 35 1,000 7,437E-04 0,02801426 ! meiosis I GO:0007127 61 36 1,000 7,869E-04 0,02917817 ! development of primary male sexual characteristics GO:0046546 52 36 1,000 7,869E-04 0,02872927 ! positive regulation of DNA metabolic process GO:0051054 64 37 1,000 8,313E-04 0,02988976 ! ear morphogenesis GO:0042471 50 37 1,000 8,313E-04 0,02944364 ! odontogenesis GO:0042476 60 37 1,000 8,313E-04 0,02901065 ! keratinocyte differentiation GO:0030216 55 37 1,000 8,313E-04 0,0285902 ! positive regulation of leukocyte proliferation GO:0070665 64 39 1,000 9,236E-04 0,03131134 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! negative regulation of protein complex disassembly GO:0043242 78 42 1,000 1,071E-03 0,03579402 ! male sex differentiation GO:0046661 62 42 1,000 1,071E-03 0,03529688 ! epidermal cell differentiation GO:0009913 61 42 1,000 1,071E-03 0,03481336 ! response to calcium ion GO:0051592 65 43 1,000 1,122E-03 0,03599287 ! epithelial cell differentiation GO:0030855 64 44 1,000 1,175E-03 0,03717792 ! inner ear development GO:0048839 66 44 1,000 1,175E-03 0,03668874 ! positive regulation of cell cycle GO:0045787 83 45 1,000 1,229E-03 0,03786993 ! epithelial tube morphogenesis GO:0060562 73 46 1,000 1,284E-03 0,03905626 ! branching morphogenesis of a tube GO:0048754 85 47 1,000 1,34E-03 0,04024744 ! embryonic skeletal system development GO:0048706 65 47 1,000 1,34E-03 0,03974435 ! regulation of protein complex disassembly GO:0043244 88 49 1,000 1,456E-03 0,04264339 ! endocrine system development GO:0035270 86 49 1,000 1,456E-03 0,04212335 ! regulation of mast cell proliferation GO:0070666 80 50 1,000 1,515E-03 0,04331938 ! skeletal muscle fiber development GO:0048741 79 52 1,000 1,638E-03 0,04626774 ! regulation of DNA replication GO:0006275 88 52 1,000 1,638E-03 0,04572342 ! protein amino acid autophosphorylation GO:0046777 97 52 1,000 1,638E-03 0,04519175 ! muscle fiber development GO:0048747 80 53 1,000 1,701E-03 0,04639156 ! regulation of leukocyte proliferation GO:0070663 88 53 1,000 1,701E-03 0,04586438 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of cell migration GO:0030335 100 54 1,000 1,765E-03 0,04706018 ! negative regulation of cytoskeleton organization GO:0051494 96 54 1,000 1,765E-03 0,04653729 ! morphogenesis of a branching structure GO:0001763 99 54 1,000 1,765E-03 0,04602589 ! ear development GO:0043583 83 55 1,000 1,83E-03 0,04721038 ! positive regulation of growth GO:0045927 78 58 1,000 2,033E-03 0,05187687 ! DNA damage response, signal transduction GO:0042770 105 58 1,000 2,033E-03 0,05132499 ! skeletal system morphogenesis GO:0048705 90 59 1,000 2,103E-03 0,05252974 ! kidney development GO:0001822 101 60 1,000 2,174E-03 0,05373731 ! positive regulation of cell motion GO:0051272 110 60 1,000 2,174E-03 0,05318332 ! negative regulation of cell growth GO:0030308 123 65 1,000 2,546E-03 0,0616434 ! lung development GO:0030324 112 66 1,000 2,623E-03 0,06288348 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 1,000 2,623E-03 0,06225464 ! negative regulation of cell size GO:0045792 125 67 1,000 2,702E-03 0,06349024 ! extracellular matrix organization GO:0030198 117 67 1,000 2,702E-03 0,06286778 ! meiosis GO:0007126 110 68 1,000 2,782E-03 0,064099 GO:0051327|M phase of meiotic cell cycle, ! regulation of caspase activity GO:0043281 104 68 1,000 2,782E-03 0,06348266 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 2,782E-03 0,06287806 ! respiratory tube development GO:0030323 117 69 1,000 2,863E-03 0,06409912 ! urogenital system development GO:0001655 114 69 1,000 2,863E-03 0,06350006 ! meiotic cell cycle GO:0051321 111 69 1,000 2,863E-03 0,0629121 ! regulation of endopeptidase activity GO:0052548 106 70 1,000 2,945E-03 0,06412328 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 1,000 2,945E-03 0,06354034 ! homeostasis of number of cells GO:0048872 109 72 1,000 3,113E-03 0,06655082 ! respiratory system development GO:0060541 123 72 1,000 3,113E-03 0,06595662 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 1,000 3,198E-03 0,06716727 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 1,000 3,198E-03 0,06657808 ! development of primary sexual characteristics GO:0045137 107 74 1,000 3,285E-03 0,06778487 ! regulation of neuron differentiation GO:0045664 130 74 1,000 3,285E-03 0,06720052 ! regulation of peptidase activity GO:0052547 113 75 1,000 3,373E-03 0,06840352 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 3,373E-03 0,06782383 ! response to metal ion GO:0010038 114 76 1,000 3,461E-03 0,06902311 ! phosphoinositide-mediated signaling GO:0048015 122 76 1,000 3,461E-03 0,06844791 ! positive regulation of ligase activity GO:0051351 114 76 1,000 3,461E-03 0,06788223 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 3,551E-03 0,06907269 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 127 78 1,000 3,642E-03 0,07026474 ! negative regulation of growth GO:0045926 140 78 1,000 3,642E-03 0,06969809 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 1,000 3,734E-03 0,07088662 ! tube morphogenesis GO:0035239 140 80 1,000 3,827E-03 0,07207663 ! response to unfolded protein GO:0006986 113 80 1,000 3,827E-03 0,07150909 ! negative regulation of organelle organization GO:0010639 136 80 1,000 3,827E-03 0,07095043 ! response to inorganic substance GO:0010035 127 81 1,000 3,921E-03 0,0721321 ! regulation of ligase activity GO:0051340 129 82 1,000 4,016E-03 0,07331523 ! positive regulation of protein modification process GO:0031401 126 83 1,000 4,113E-03 0,07449973 ! positive regulation of lymphocyte activation GO:0051251 134 83 1,000 4,113E-03 0,07393534 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 1,000 4,308E-03 0,07687259 GO:0010498|proteasomal protein catabolic process, ! sex differentiation GO:0007548 126 85 1,000 4,308E-03 0,07629891 ! response to protein stimulus GO:0051789 127 85 1,000 4,308E-03 0,07573373 ! gland development GO:0048732 170 87 1,000 4,509E-03 0,07866737 ! regulation of DNA metabolic process GO:0051052 152 90 1,000 4,817E-03 0,08342847 ! microtubule cytoskeleton organization GO:0000226 133 90 1,000 4,817E-03 0,08282392 ! skeletal muscle tissue development GO:0007519 135 90 1,000 4,817E-03 0,08222806 GO:0060538|skeletal muscle organ development, ! positive regulation of cell activation GO:0050867 146 90 1,000 4,817E-03 0,08164072 GO:0002696|positive regulation of leukocyte activation, ! cell cycle arrest GO:0007050 171 93 1,000 5,134E-03 0,08640535 ! regulation of neurogenesis GO:0050767 179 97 1,000 5,572E-03 0,09311636 ! reproductive developmental process GO:0003006 149 97 1,000 5,572E-03 0,0924652 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 5,77E-03 0,09507822 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 5,77E-03 0,09442251 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 5,77E-03 0,09377578 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 5,77E-03 0,09313785 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 5,77E-03 0,09250854 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 5,77E-03 0,09188768 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,77E-03 0,09127509 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 5,77E-03 0,09067062 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 5,77E-03 0,0900741 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 5,77E-03 0,08948539 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 5,77E-03 0,08890431 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 5,77E-03 0,08833073 ! response to oxygen radical GO:0000305 11 5 0,000 5,77E-03 0,08776451 ! negative regulation of bone resorption GO:0045779 11 5 0,000 5,77E-03 0,0872055 ! myoblast cell fate commitment GO:0048625 8 5 0,000 5,77E-03 0,08665357 ! nucleotide-sugar transport GO:0015780 8 5 0,000 5,77E-03 0,08610858 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 5,77E-03 0,0855704 ! regulation of interferon-beta production GO:0032648 5 5 0,000 5,77E-03 0,08503891 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 5,77E-03 0,08451397 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 5,77E-03 0,08399548 ! female meiosis GO:0007143 8 5 0,000 5,77E-03 0,08348332 ! nose development GO:0043584 10 5 0,000 5,77E-03 0,08297736 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 5,77E-03 0,08247749 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 5,77E-03 0,08198362 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 5,77E-03 0,08149562 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 5,77E-03 0,0810134 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 5,77E-03 0,08053685 ! cobalt ion transport GO:0006824 9 5 0,000 5,77E-03 0,08006587 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 5,77E-03 0,07960037 ! SMAD protein complex assembly GO:0007183 10 5 0,000 5,77E-03 0,07914025 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 5,77E-03 0,07868542 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 5,77E-03 0,07823579 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 5,77E-03 0,07779127 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 5,77E-03 0,07735177 ! adaptation of signaling pathway GO:0022401 9 5 0,000 5,77E-03 0,07691721 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 5,77E-03 0,07648751 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 5,77E-03 0,07606258 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 5,77E-03 0,07564234 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 5,77E-03 0,07522672 ! negative regulation of histone modification GO:0031057 7 5 0,000 5,77E-03 0,07481565 ! malate metabolic process GO:0006108 8 5 0,000 5,77E-03 0,07440904 ! positive regulation of histone modification GO:0031058 6 5 0,000 5,77E-03 0,07400683 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 5,77E-03 0,07360895 ! clathrin coat assembly GO:0048268 11 5 0,000 5,77E-03 0,07321532 ! Notch receptor processing GO:0007220 8 5 0,000 5,77E-03 0,07282587 ! phototransduction, visible light GO:0007603 7 5 0,000 5,77E-03 0,07244055 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,77E-03 0,07205928 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 5,77E-03 0,07168201 ! mating behavior GO:0007617 6 5 0,000 5,77E-03 0,07130867 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 5,77E-03 0,07093919 ! copulation GO:0007620 8 5 0,000 5,77E-03 0,07057353 ! protein maturation by protein folding GO:0022417 13 5 0,000 5,77E-03 0,07021161 ! embryonic hemopoiesis GO:0035162 13 5 0,000 5,77E-03 0,06985339 ! regulation of potassium ion transport GO:0043266 9 5 0,000 5,77E-03 0,0694988 ! apoptotic cell clearance GO:0043277 14 5 0,000 5,77E-03 0,0691478 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 5,77E-03 0,06880032 ! lipoprotein particle clearance GO:0034381 9 5 0,000 5,77E-03 0,06845632 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 5,77E-03 0,06811574 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 5,77E-03 0,06777853 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 5,77E-03 0,06744465 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 5,77E-03 0,06711404 ! response to axon injury GO:0048678 8 5 0,000 5,77E-03 0,06678665 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,77E-03 0,06646245 ! response to protozoan GO:0001562 10 5 0,000 5,77E-03 0,06614137 ! negative regulation of heart contraction GO:0045822 12 5 0,000 5,77E-03 0,06582338 ! lymph vessel development GO:0001945 8 5 0,000 5,77E-03 0,06550844 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 5,77E-03 0,06519649 ! endochondral ossification GO:0001958 13 5 0,000 5,77E-03 0,06488751 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 5,77E-03 0,06458143 ! single strand break repair GO:0000012 5 5 0,000 5,77E-03 0,06427823 ! parathyroid gland development GO:0060017 8 5 0,000 5,77E-03 0,06397787 ! anagen GO:0042640 7 5 0,000 5,77E-03 0,0636803 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 5,77E-03 0,06338548 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 5,77E-03 0,06309338 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 5,77E-03 0,06280396 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 5,77E-03 0,06251719 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 5,77E-03 0,06223302 ! smooth muscle tissue development GO:0048745 14 5 0,000 5,77E-03 0,06195142 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,77E-03 0,06167236 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 5,77E-03 0,0613958 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 5,77E-03 0,06112171 ! cardiac muscle fiber development GO:0048739 8 5 0,000 5,77E-03 0,06085006 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,77E-03 0,06058081 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 5,77E-03 0,06031394 ! neutrophil mediated immunity GO:0002446 6 5 0,000 5,77E-03 0,0600494 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,77E-03 0,05978718 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 5,77E-03 0,05952723 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 5,77E-03 0,05926954 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 5,77E-03 0,05901407 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 5,77E-03 0,05876079 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 5,77E-03 0,05850967 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 5,77E-03 0,0582607 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 5,77E-03 0,05801383 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 5,77E-03 0,05776905 ! tyrosine catabolic process GO:0006572 7 5 0,000 5,77E-03 0,05752632 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 5,77E-03 0,05728562 ! proline biosynthetic process GO:0006561 6 5 0,000 5,77E-03 0,05704693 ! L-serine biosynthetic process GO:0006564 6 5 0,000 5,77E-03 0,05681022 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 5,77E-03 0,05657547 ! polyol catabolic process GO:0046174 7 5 0,000 5,77E-03 0,05634265 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 5,77E-03 0,05611174 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 5,77E-03 0,05588271 ! sister chromatid cohesion GO:0007062 10 5 0,000 5,77E-03 0,05565554 ! response to ATP GO:0033198 6 5 0,000 5,77E-03 0,05543022 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 5,77E-03 0,05520671 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 5,77E-03 0,054985 ! neutrophil activation GO:0042119 6 5 0,000 5,77E-03 0,05476506 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 5,77E-03 0,05454687 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 5,77E-03 0,05433041 ! response to food GO:0032094 5 5 0,000 5,77E-03 0,05411567 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 5,77E-03 0,05390261 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 5,77E-03 0,05369123 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 5,77E-03 0,0534815 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,77E-03 0,0532734 ! paraxial mesoderm development GO:0048339 9 5 0,000 5,77E-03 0,05306691 ! forebrain neuron development GO:0021884 7 5 0,000 5,77E-03 0,05286202 ! melanosome organization GO:0032438 7 5 0,000 5,77E-03 0,05265871 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 5,77E-03 0,05245695 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 5,77E-03 0,05225673 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,77E-03 0,05205804 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 5,77E-03 0,05186085 ! mesodermal cell fate determination GO:0007500 7 5 0,000 5,77E-03 0,05166515 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,77E-03 0,05147092 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 5,77E-03 0,05127814 ! nucleoside salvage GO:0043174 7 5 0,000 5,77E-03 0,05108681 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 5,77E-03 0,05089689 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 5,77E-03 0,05070838 ! negative regulation of platelet activation GO:0010544 8 5 0,000 5,77E-03 0,05052127 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 5,77E-03 0,05033553 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 5,77E-03 0,05015115 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 5,77E-03 0,04996812 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 5,77E-03 0,04978641 ! early endosome to late endosome transport GO:0045022 11 5 0,000 5,77E-03 0,04960603 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 5,77E-03 0,04942695 ! depyrimidination GO:0045008 8 5 0,000 5,77E-03 0,04924915 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,77E-03 0,04907263 ! 5S class rRNA transcription GO:0042791 8 5 0,000 5,77E-03 0,04889737 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 5,77E-03 0,04872336 ! neuronal ion channel clustering GO:0045161 8 5 0,000 5,77E-03 0,04855058 ! sodium ion homeostasis GO:0055078 6 5 0,000 5,77E-03 0,04837902 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 5,77E-03 0,04820868 ! monocyte differentiation GO:0030224 7 5 0,000 5,77E-03 0,04803952 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 5,77E-03 0,04787155 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 5,77E-03 0,04770475 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 5,77E-03 0,04753911 ! response to UV-C GO:0010225 7 5 0,000 5,77E-03 0,04737462 ! protein targeting to vacuole GO:0006623 6 5 0,000 5,77E-03 0,04721125 ! activated T cell proliferation GO:0050798 7 5 0,000 5,77E-03 0,04704902 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 5,77E-03 0,04688789 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 5,77E-03 0,04672786 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 5,77E-03 0,04656892 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 5,77E-03 0,04641106 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 5,77E-03 0,04625427 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 5,77E-03 0,04609853 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 5,77E-03 0,04594384 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 5,77E-03 0,04579018 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 5,77E-03 0,04563755 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 5,77E-03 0,04548593 ! response to cadmium ion GO:0046686 8 5 0,000 5,77E-03 0,04533531 ! melanosome transport GO:0032402 8 5 0,000 5,77E-03 0,04518569 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,77E-03 0,04503705 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 5,77E-03 0,04488939 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 5,77E-03 0,04474269 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 5,77E-03 0,04459695 ! positive T cell selection GO:0043368 10 5 0,000 5,77E-03 0,04445216 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 5,77E-03 0,0443083 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 5,77E-03 0,04416537 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 5,77E-03 0,04402336 ! ribosomal subunit assembly GO:0042257 5 5 0,000 5,77E-03 0,04388226 ! base conversion or substitution editing GO:0016553 6 5 0,000 5,77E-03 0,04374206 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 5,77E-03 0,04360275 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 5,77E-03 0,04346433 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 5,77E-03 0,04332678 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 5,77E-03 0,04319011 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 5,77E-03 0,04305429 ! histone demethylation GO:0016577 10 5 0,000 5,77E-03 0,04291932 ! mitotic recombination GO:0006312 10 5 0,000 5,77E-03 0,0427852 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 5,77E-03 0,04265191 ! regulation of sterol transport GO:0032371 7 5 0,000 5,77E-03 0,04251945 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 5,77E-03 0,04238781 ! sympathetic nervous system development GO:0048485 13 5 0,000 5,77E-03 0,04225699 ! enteric nervous system development GO:0048484 9 5 0,000 5,77E-03 0,04212697 ! oxygen homeostasis GO:0032364 8 5 0,000 5,77E-03 0,04199774 ! establishment of planar polarity GO:0001736 7 5 0,000 5,77E-03 0,04186931 ! lymphocyte costimulation GO:0031294 12 5 0,000 5,77E-03 0,04174166 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 5,77E-03 0,04161478 ! transcription termination GO:0006353 8 5 0,000 5,77E-03 0,04148868 ! plasminogen activation GO:0031639 5 5 0,000 5,77E-03 0,04136334 ! B cell homeostasis GO:0001782 12 5 0,000 5,77E-03 0,04123875 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 5,77E-03 0,04111491 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 5,77E-03 0,04099181 ! regulation of hair follicle development GO:0051797 9 5 0,000 5,77E-03 0,04086944 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 5,77E-03 0,04074781 ! apical protein localization GO:0045176 8 5 0,000 5,77E-03 0,0406269 ! definitive hemopoiesis GO:0060216 5 5 0,000 5,77E-03 0,0405067 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 5,77E-03 0,04038721 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 5,77E-03 0,04026842 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 5,77E-03 0,04015033 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 5,77E-03 0,04003294 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 5,77E-03 0,03991622 ! regulation of centrosome duplication GO:0010824 6 5 0,000 5,77E-03 0,03980019 ! disaccharide metabolic process GO:0005984 9 5 0,000 5,77E-03 0,03968482 ! galactolipid metabolic process GO:0019374 8 5 0,000 5,77E-03 0,03957013 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 5,77E-03 0,03945609 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 5,77E-03 0,03934271 ! determination of adult lifespan GO:0008340 8 5 0,000 5,77E-03 0,03922998 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 5,77E-03 0,0391179 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 5,77E-03 0,03900645 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 5,77E-03 0,03889564 ! T cell activation during immune response GO:0002286 9 5 0,000 5,77E-03 0,03878545 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 5,77E-03 0,03867589 ! negative regulation of lipase activity GO:0060192 7 5 0,000 5,77E-03 0,03856694 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 5,77E-03 0,03845861 ! neural plate development GO:0001840 7 5 0,000 5,77E-03 0,03835088 ! regulation of sensory perception GO:0051931 6 5 0,000 5,77E-03 0,03824375 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 5,77E-03 0,03813723 ! regulation of histone acetylation GO:0035065 7 5 0,000 5,77E-03 0,03803129 ! sensory cilium assembly GO:0035058 6 5 0,000 5,77E-03 0,03792594 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 5,77E-03 0,03782117 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 5,77E-03 0,03771698 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 5,77E-03 0,03761336 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 5,77E-03 0,03751031 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 5,77E-03 0,03740782 ! receptor biosynthetic process GO:0032800 6 5 0,000 5,77E-03 0,0373059 ! penetration of zona pellucida GO:0007341 9 5 0,000 5,77E-03 0,03720452 ! drug metabolic process GO:0017144 5 5 0,000 5,77E-03 0,0371037 ! protein amino acid prenylation GO:0018346 9 5 0,000 5,77E-03 0,03700342 ! organ regeneration GO:0031100 7 5 0,000 5,77E-03 0,03690368 ! carnitine metabolic process GO:0009437 5 5 0,000 5,77E-03 0,03680447 GO:0006577|betaine metabolic process, ! cell fate commitment GO:0045165 165 99 1,000 5,797E-03 0,03688205 ! tRNA transcription GO:0009304 11 6 0,000 6,92E-03 0,04390491 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 6,92E-03 0,04378783 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 6,92E-03 0,04367137 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 6,92E-03 0,04355553 ! regulation of helicase activity GO:0051095 11 6 0,000 6,92E-03 0,0434403 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 6,92E-03 0,04332569 ! sleep GO:0030431 13 6 0,000 6,92E-03 0,04321167 ! positive regulation of axon extension GO:0045773 10 6 0,000 6,92E-03 0,04309825 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 6,92E-03 0,04298543 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 6,92E-03 0,0428732 ! forebrain regionalization GO:0021871 7 6 0,000 6,92E-03 0,04276155 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 6,92E-03 0,04265048 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 6,92E-03 0,04253999 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 6,92E-03 0,04243006 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 6,92E-03 0,04232071 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 6,92E-03 0,04221191 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 6,92E-03 0,04210368 ! neuron adhesion GO:0007158 9 6 0,000 6,92E-03 0,041996 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 6,92E-03 0,04188886 ! signal peptide processing GO:0006465 8 6 0,000 6,92E-03 0,04178228 ! embryonic camera-type eye development GO:0031076 11 6 0,000 6,92E-03 0,04167623 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 6,92E-03 0,04157072 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 6,92E-03 0,04146574 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 6,92E-03 0,0413613 ! fibril organization GO:0043206 13 6 0,000 6,92E-03 0,04125737 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 6,92E-03 0,04115397 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 6,92E-03 0,04105109 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 6,92E-03 0,04094871 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 6,92E-03 0,04084685 ! protein refolding GO:0042026 13 6 0,000 6,92E-03 0,0407455 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 6,92E-03 0,04064464 ! rhythmic behavior GO:0007622 14 6 0,000 6,92E-03 0,04054428 ! glial cell fate commitment GO:0021781 17 6 0,000 6,92E-03 0,04044442 ! erythrocyte maturation GO:0043249 7 6 0,000 6,92E-03 0,04034505 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 6,92E-03 0,04024616 ! protein amino acid dealkylation GO:0008214 12 6 0,000 6,92E-03 0,04014776 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 6,92E-03 0,04004984 ! regulation of odontogenesis GO:0042481 8 6 0,000 6,92E-03 0,0399524 ! mechanosensory behavior GO:0007638 8 6 0,000 6,92E-03 0,03985542 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 6,92E-03 0,03975892 ! negative regulation of endocytosis GO:0045806 8 6 0,000 6,92E-03 0,03966289 ! response to interferon-gamma GO:0034341 12 6 0,000 6,92E-03 0,03956731 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 6,92E-03 0,0394722 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 6,92E-03 0,03937754 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 6,92E-03 0,03928334 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 6,92E-03 0,03918958 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 6,92E-03 0,03909627 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 6,92E-03 0,03900341 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 6,92E-03 0,03891098 ! cGMP-mediated signaling GO:0019934 11 6 0,000 6,92E-03 0,03881899 ! activation of MAPKKK activity GO:0000185 11 6 0,000 6,92E-03 0,03872744 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 6,92E-03 0,03863632 ! protein lipoylation GO:0009249 10 6 0,000 6,92E-03 0,03854562 ! pigment granule organization GO:0048753 11 6 0,000 6,92E-03 0,03845535 ! drug transport GO:0015893 6 6 0,000 6,92E-03 0,0383655 ! transepithelial chloride transport GO:0030321 10 6 0,000 6,92E-03 0,03827607 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 6,92E-03 0,03818706 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 6,92E-03 0,03809846 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 6,92E-03 0,03801027 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 6,92E-03 0,03792248 ! glutamate catabolic process GO:0006538 11 6 0,000 6,92E-03 0,0378351 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 6,92E-03 0,03774813 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 6,92E-03 0,03766155 ! adenohypophysis development GO:0021984 10 6 0,000 6,92E-03 0,03757537 ! response to pH GO:0009268 10 6 0,000 6,92E-03 0,03748958 ! hyperosmotic response GO:0006972 9 6 0,000 6,92E-03 0,03740418 ! microtubule nucleation GO:0007020 10 6 0,000 6,92E-03 0,03731917 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 6,92E-03 0,03723455 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 6,92E-03 0,0371503 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 6,92E-03 0,03706644 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 6,92E-03 0,03698296 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 6,92E-03 0,03689985 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 6,92E-03 0,03681712 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 6,92E-03 0,03673475 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 6,92E-03 0,03665276 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 6,92E-03 0,03657112 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 6,92E-03 0,03648985 ! purine salvage GO:0043101 9 6 0,000 6,92E-03 0,03640895 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 6,92E-03 0,0363284 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 6,92E-03 0,0362482 ! nucleoside transport GO:0015858 7 6 0,000 6,92E-03 0,03616836 ! organic alcohol transport GO:0015850 9 6 0,000 6,92E-03 0,03608887 ! T cell mediated immunity GO:0002456 12 6 0,000 6,92E-03 0,03600973 ! folic acid transport GO:0015884 11 6 0,000 6,92E-03 0,03593093 ! male sex determination GO:0030238 11 6 0,000 6,92E-03 0,03585248 ! carnitine transport GO:0015879 8 6 0,000 6,92E-03 0,03577437 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 6,92E-03 0,0356966 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,92E-03 0,03561916 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 6,92E-03 0,03554207 ! positive regulation of exocytosis GO:0045921 9 6 0,000 6,92E-03 0,0354653 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 6,92E-03 0,03538887 ! parturition GO:0007567 13 6 0,000 6,92E-03 0,03531276 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 6,92E-03 0,03523698 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 6,92E-03 0,03516153 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 6,92E-03 0,0350864 ! regulation of centrosome cycle GO:0046605 8 6 0,000 6,92E-03 0,03501159 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 6,92E-03 0,03493709 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 6,92E-03 0,03486292 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 6,92E-03 0,03478906 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 6,92E-03 0,03471551 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 6,92E-03 0,03464227 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 6,92E-03 0,03456934 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 6,92E-03 0,03449671 ! neural nucleus development GO:0048857 12 6 0,000 6,92E-03 0,03442439 ! forebrain morphogenesis GO:0048853 14 6 0,000 6,92E-03 0,03435237 ! hyaluronan metabolic process GO:0030212 7 6 0,000 6,92E-03 0,03428066 ! purine base biosynthetic process GO:0009113 14 6 0,000 6,92E-03 0,03420924 ! interaction with symbiont GO:0051702 9 6 0,000 6,92E-03 0,03413812 ! regulation of dendrite development GO:0050773 13 6 0,000 6,92E-03 0,03406729 ! anterograde axon cargo transport GO:0008089 9 6 0,000 6,92E-03 0,03399676 ! positive regulation of organ growth GO:0046622 7 6 0,000 6,92E-03 0,03392652 ! eating behavior GO:0042755 6 6 0,000 6,92E-03 0,03385657 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 6,92E-03 0,0337869 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 6,92E-03 0,03371752 ! response to copper ion GO:0046688 9 6 0,000 6,92E-03 0,03364843 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 6,92E-03 0,03357962 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 6,92E-03 0,03351109 ! establishment of melanosome localization GO:0032401 9 6 0,000 6,92E-03 0,03344284 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,92E-03 0,03337487 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 6,92E-03 0,03330717 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 6,92E-03 0,03323975 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,92E-03 0,0331726 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,92E-03 0,03310571 ! hair follicle maturation GO:0048820 8 6 0,000 6,92E-03 0,0330391 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 6,92E-03 0,03297276 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 6,92E-03 0,03290668 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 6,92E-03 0,03284087 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 6,92E-03 0,03277532 ! rhombomere development GO:0021546 6 6 0,000 6,92E-03 0,03271003 ! positive regulation of Rho GTPase activity GO:0032321 12 6 0,000 6,92E-03 0,032645 ! G2 phase GO:0051319 15 6 0,000 6,92E-03 0,03258023 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 6,92E-03 0,03251571 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 6,92E-03 0,03245145 ! muscle cell proliferation GO:0033002 9 6 0,000 6,92E-03 0,03238745 ! membrane to membrane docking GO:0022614 12 6 0,000 6,92E-03 0,03232369 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 6,92E-03 0,03226019 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 6,92E-03 0,03219693 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 6,92E-03 0,03213392 ! receptor internalization GO:0031623 9 6 0,000 6,92E-03 0,03207116 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 6,92E-03 0,03200864 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 6,92E-03 0,03194637 ! coenzyme A metabolic process GO:0015936 9 6 0,000 6,92E-03 0,03188434 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 6,92E-03 0,03182255 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 6,92E-03 0,031761 ! peptidyl-histidine modification GO:0018202 10 6 0,000 6,92E-03 0,03169968 ! axonal fasciculation GO:0007413 10 6 0,000 6,92E-03 0,0316386 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 6,92E-03 0,03157776 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 6,92E-03 0,03151715 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 6,92E-03 0,03145677 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 6,92E-03 0,03139662 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 6,92E-03 0,03133671 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 6,92E-03 0,03127702 ! progesterone metabolic process GO:0042448 8 6 0,000 6,92E-03 0,03121756 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 6,92E-03 0,03115832 ! glycolipid catabolic process GO:0019377 14 6 0,000 6,92E-03 0,03109931 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 6,92E-03 0,03104052 ! negative regulation of axon extension GO:0030517 13 6 0,000 6,92E-03 0,03098195 ! removal of superoxide radicals GO:0019430 10 6 0,000 6,92E-03 0,03092361 ! triglyceride catabolic process GO:0019433 8 6 0,000 6,92E-03 0,03086548 ! protein modification by small protein removal GO:0070646 10 6 0,000 6,92E-03 0,03080757 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 6,92E-03 0,03074988 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 6,92E-03 0,0306924 ! glial cell migration GO:0008347 11 6 0,000 6,92E-03 0,03063514 ! blastocyst growth GO:0001832 17 6 0,000 6,92E-03 0,03057809 ! pigment granule transport GO:0051904 12 6 0,000 6,92E-03 0,03052125 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 6,92E-03 0,03046463 ! cerebellar cortex formation GO:0021697 9 6 0,000 6,92E-03 0,03040821 ! catecholamine transport GO:0051937 7 6 0,000 6,92E-03 0,030352 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 6,92E-03 0,030296 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 6,92E-03 0,03024021 ! organ or tissue specific immune response GO:0002251 7 6 0,000 6,92E-03 0,03018462 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 6,92E-03 0,03012924 ! spindle assembly GO:0051225 6 6 0,000 6,92E-03 0,03007406 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 6,92E-03 0,03001908 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 6,92E-03 0,0299643 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 6,92E-03 0,02990972 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 6,92E-03 0,02985534 ! NAD biosynthetic process GO:0009435 9 6 0,000 6,92E-03 0,02980115 ! positive regulation of coagulation GO:0050820 11 6 0,000 6,92E-03 0,02974716 ! cellular anion homeostasis GO:0030002 9 6 0,000 6,92E-03 0,02969337 GO:0055081|anion homeostasis, ! behavioral response to cocaine GO:0048148 13 7 0,000 8,069E-03 0,03456062 ! autophagic vacuole formation GO:0000045 12 7 0,000 8,069E-03 0,03449835 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 8,069E-03 0,0344363 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 8,069E-03 0,03437448 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 8,069E-03 0,03431288 ! prostate gland development GO:0030850 11 7 0,000 8,069E-03 0,03425149 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 8,069E-03 0,03419033 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 8,069E-03 0,03412939 ! synaptonemal complex assembly GO:0007130 11 7 0,000 8,069E-03 0,03406866 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 8,069E-03 0,03400814 ! male meiosis GO:0007140 10 7 0,000 8,069E-03 0,03394785 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,069E-03 0,03388776 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 8,069E-03 0,03382789 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 8,069E-03 0,03376823 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 8,069E-03 0,03370878 ! oligopeptide transport GO:0006857 11 7 0,000 8,069E-03 0,03364953 ! protein amino acid sulfation GO:0006477 9 7 0,000 8,069E-03 0,0335905 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 8,069E-03 0,03353167 ! establishment of tissue polarity GO:0007164 10 7 0,000 8,069E-03 0,03347305 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 8,069E-03 0,03341463 ! RNA methylation GO:0001510 11 7 0,000 8,069E-03 0,03335642 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 8,069E-03 0,03329841 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 8,069E-03 0,0332406 ! pericardium development GO:0060039 9 7 0,000 8,069E-03 0,03318299 ! macrophage chemotaxis GO:0048246 10 7 0,000 8,069E-03 0,03312558 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 8,069E-03 0,03306837 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 8,069E-03 0,03301135 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 8,069E-03 0,03295454 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 8,069E-03 0,03289791 ! cerebral cortex cell migration GO:0021795 11 7 0,000 8,069E-03 0,03284148 ! opsonization GO:0008228 9 7 0,000 8,069E-03 0,03278525 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 8,069E-03 0,03272921 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 8,069E-03 0,03267335 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 8,069E-03 0,03261769 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 8,069E-03 0,03256222 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 8,069E-03 0,03250694 ! chemosensory behavior GO:0007635 9 7 0,000 8,069E-03 0,03245184 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 8,069E-03 0,03239693 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 8,069E-03 0,03234221 ! leukocyte degranulation GO:0043299 11 7 0,000 8,069E-03 0,03228767 ! positive regulation of glycolysis GO:0045821 13 7 0,000 8,069E-03 0,03223331 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 8,069E-03 0,03217914 ! positive regulation of heart rate GO:0010460 11 7 0,000 8,069E-03 0,03212514 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,069E-03 0,03207133 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 8,069E-03 0,0320177 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 8,069E-03 0,03196425 ! spinal cord patterning GO:0021511 9 7 0,000 8,069E-03 0,03191098 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 8,069E-03 0,03185788 ! thymic T cell selection GO:0045061 15 7 0,000 8,069E-03 0,03180496 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 8,069E-03 0,03175221 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 8,069E-03 0,03169964 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 8,069E-03 0,03164725 ! ovulation GO:0030728 8 7 0,000 8,069E-03 0,03159503 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 8,069E-03 0,03154297 ! histidine metabolic process GO:0006547 7 7 0,000 8,069E-03 0,03149109 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 8,069E-03 0,03143938 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 8,069E-03 0,03138784 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 8,069E-03 0,03133647 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 8,069E-03 0,03128527 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 8,069E-03 0,03123423 ! thyroid hormone generation GO:0006590 11 7 0,000 8,069E-03 0,03118336 ! endosome organization GO:0007032 10 7 0,000 8,069E-03 0,03113266 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 8,069E-03 0,03108212 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 8,069E-03 0,03103174 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 8,069E-03 0,03098153 ! urea metabolic process GO:0019627 9 7 0,000 8,069E-03 0,03093148 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 8,069E-03 0,03088159 ! vesicle fusion GO:0006906 15 7 0,000 8,069E-03 0,03083186 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 8,069E-03 0,03078229 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 8,069E-03 0,03073288 ! intracellular pH reduction GO:0051452 11 7 0,000 8,069E-03 0,03068363 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 8,069E-03 0,03063454 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 8,069E-03 0,0305856 ! organ growth GO:0035265 13 7 0,000 8,069E-03 0,03053682 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 8,069E-03 0,03048819 ! Rac protein signal transduction GO:0016601 7 7 0,000 8,069E-03 0,03043972 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 8,069E-03 0,03039141 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 8,069E-03 0,03034324 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 8,069E-03 0,03029523 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 8,069E-03 0,03024737 ! rRNA modification GO:0000154 12 7 0,000 8,069E-03 0,03019966 ! negative regulation of translational initiation GO:0045947 9 7 0,000 8,069E-03 0,0301521 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 8,069E-03 0,03010469 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 8,069E-03 0,03005743 ! protein heterooligomerization GO:0051291 10 7 0,000 8,069E-03 0,03001032 ! response to UV-B GO:0010224 11 7 0,000 8,069E-03 0,02996336 ! astrocyte development GO:0014002 15 7 0,000 8,069E-03 0,02991654 ! intermediate filament organization GO:0045109 12 7 0,000 8,069E-03 0,02986987 ! cardiac muscle cell development GO:0055013 9 7 0,000 8,069E-03 0,02982334 ! fibrinolysis GO:0042730 9 7 0,000 8,069E-03 0,02977696 ! peptidyl-arginine modification GO:0018195 9 7 0,000 8,069E-03 0,02973072 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 8,069E-03 0,02968463 ! blastoderm segmentation GO:0007350 11 7 0,000 8,069E-03 0,02963868 ! skeletal muscle contraction GO:0003009 8 7 0,000 8,069E-03 0,02959287 ! B cell lineage commitment GO:0002326 17 7 0,000 8,069E-03 0,0295472 ! DNA topological change GO:0006265 10 7 0,000 8,069E-03 0,02950167 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 8,069E-03 0,02945629 ! melanosome localization GO:0032400 10 7 0,000 8,069E-03 0,02941104 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 8,069E-03 0,02936593 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 8,069E-03 0,02932096 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 8,069E-03 0,02927612 ! mast cell activation GO:0045576 10 7 0,000 8,069E-03 0,02923143 ! multicellular organismal aging GO:0010259 11 7 0,000 8,069E-03 0,02918687 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 8,069E-03 0,02914244 ! gas homeostasis GO:0033483 12 7 0,000 8,069E-03 0,02909815 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 8,069E-03 0,029054 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 8,069E-03 0,02900998 ! Schwann cell development GO:0014044 16 7 0,000 8,069E-03 0,02896609 ! dendrite morphogenesis GO:0048813 12 7 0,000 8,069E-03 0,02892233 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 8,069E-03 0,02887871 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 8,069E-03 0,02883522 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 8,069E-03 0,02879186 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 8,069E-03 0,02874863 ! neural tube patterning GO:0021532 8 7 0,000 8,069E-03 0,02870553 ! histone ubiquitination GO:0016574 10 7 0,000 8,069E-03 0,02866255 ! regulation of meiosis GO:0040020 12 7 0,000 8,069E-03 0,02861971 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 8,069E-03 0,02857699 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 8,069E-03 0,0285344 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 8,069E-03 0,02849194 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 8,069E-03 0,02844961 ! regulation of lipid transport GO:0032368 13 7 0,000 8,069E-03 0,0284074 ! regulation of cell division GO:0051302 9 7 0,000 8,069E-03 0,02836531 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 8,069E-03 0,02832335 ! neutrophil homeostasis GO:0001780 8 7 0,000 8,069E-03 0,02828151 ! regulation of macrophage activation GO:0043030 12 7 0,000 8,069E-03 0,0282398 ! negative regulation of nuclear division GO:0051784 18 7 0,000 8,069E-03 0,02819821 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 8,069E-03 0,02815674 ! diuresis GO:0030146 11 7 0,000 8,069E-03 0,0281154 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 8,069E-03 0,02807417 ! positive regulation of epidermis development GO:0045684 11 7 0,000 8,069E-03 0,02803307 ! thiamin metabolic process GO:0006772 8 7 0,000 8,069E-03 0,02799208 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 8,069E-03 0,02795122 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 8,069E-03 0,02791047 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 8,069E-03 0,02786985 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 8,069E-03 0,02782934 ! dopamine biosynthetic process GO:0042416 15 7 0,000 8,069E-03 0,02778895 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 8,069E-03 0,02774867 ! lymph node development GO:0048535 9 7 0,000 8,069E-03 0,02770852 ! anterior/posterior axis specification GO:0009948 11 7 0,000 8,069E-03 0,02766848 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 8,069E-03 0,02762855 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 8,069E-03 0,02758874 ! positive regulation of glucose import GO:0046326 7 7 0,000 8,069E-03 0,02754904 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 8,069E-03 0,02750946 ! ATP catabolic process GO:0006200 10 7 0,000 8,069E-03 0,02746999 ! establishment of pigment granule localization GO:0051905 13 7 0,000 8,069E-03 0,02743064 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 8,069E-03 0,0273914 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 8,069E-03 0,02735226 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 8,069E-03 0,02731325 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 8,069E-03 0,02727434 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 8,069E-03 0,02723554 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,069E-03 0,02719685 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 8,069E-03 0,02715828 ! muscle adaptation GO:0043500 12 7 0,000 8,069E-03 0,02711981 ! amino sugar catabolic process GO:0046348 9 7 0,000 8,069E-03 0,02708145 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 8,069E-03 0,0270432 ! retina homeostasis GO:0001895 9 7 0,000 8,069E-03 0,02700506 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 8,069E-03 0,02696702 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 8,069E-03 0,02692909 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 8,069E-03 0,02689127 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 8,069E-03 0,02685356 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 8,069E-03 0,02681595 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 9,216E-03 0,03058702 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 9,216E-03 0,0305443 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 9,216E-03 0,0305017 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 9,216E-03 0,03045922 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 9,216E-03 0,03041686 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 9,216E-03 0,03037461 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 9,216E-03 0,03033248 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 9,216E-03 0,03029047 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 9,216E-03 0,03024857 ! cell proliferation in forebrain GO:0021846 10 8 0,000 9,216E-03 0,03020679 ! neutral lipid catabolic process GO:0046461 11 8 0,000 9,216E-03 0,03016513 ! N-glycan processing GO:0006491 12 8 0,000 9,216E-03 0,03012358 ! Golgi to endosome transport GO:0006895 16 8 0,000 9,216E-03 0,03008215 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 9,216E-03 0,03004082 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 9,216E-03 0,02999962 ! mRNA stabilization GO:0048255 16 8 0,000 9,216E-03 0,02995852 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 9,216E-03 0,02991754 ! neurotransmitter uptake GO:0001504 10 8 0,000 9,216E-03 0,02987667 ! lipoprotein transport GO:0042953 14 8 0,000 9,216E-03 0,02983591 ! membrane hyperpolarization GO:0060081 11 8 0,000 9,216E-03 0,02979526 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 9,216E-03 0,02975472 ! middle ear morphogenesis GO:0042474 9 8 0,000 9,216E-03 0,02971429 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 9,216E-03 0,02967397 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 9,216E-03 0,02963377 ! bile acid and bile salt transport GO:0015721 12 8 0,000 9,216E-03 0,02959367 ! ganglioside metabolic process GO:0001573 16 8 0,000 9,216E-03 0,02955367 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 9,216E-03 0,02951379 ! reflex GO:0060004 16 8 0,000 9,216E-03 0,02947402 ! positive regulation of isotype switching GO:0045830 16 8 0,000 9,216E-03 0,02943435 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 9,216E-03 0,02939478 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 9,216E-03 0,02935533 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 9,216E-03 0,02931598 ! glycerolipid catabolic process GO:0046503 11 8 0,000 9,216E-03 0,02927673 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 9,216E-03 0,02923759 ! hemoglobin metabolic process GO:0020027 12 8 0,000 9,216E-03 0,02919856 ! ceramide biosynthetic process GO:0046513 9 8 0,000 9,216E-03 0,02915963 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 9,216E-03 0,0291208 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 9,216E-03 0,02908207 ! adrenal gland development GO:0030325 18 8 0,000 9,216E-03 0,02904345 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 9,216E-03 0,02900493 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 9,216E-03 0,02896652 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 9,216E-03 0,0289282 ! proline metabolic process GO:0006560 9 8 0,000 9,216E-03 0,02888999 ! polyamine biosynthetic process GO:0006596 9 8 0,000 9,216E-03 0,02885187 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 9,216E-03 0,02881386 ! regulation of pigmentation during development GO:0048070 18 8 0,000 9,216E-03 0,02877595 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 9,216E-03 0,02873813 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 9,216E-03 0,02870042 ! regulation of type I interferon production GO:0032479 8 8 0,000 9,216E-03 0,0286628 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 9,216E-03 0,02862529 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 9,216E-03 0,02858787 ! galactose metabolic process GO:0006012 14 8 0,000 9,216E-03 0,02855055 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 9,216E-03 0,02851332 ! regulation of vascular permeability GO:0043114 12 8 0,000 9,216E-03 0,0284762 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 9,216E-03 0,02843917 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 9,216E-03 0,02840223 ! ruffle organization GO:0031529 12 8 0,000 9,216E-03 0,02836539 ! osteoblast development GO:0002076 14 8 0,000 9,216E-03 0,02832865 ! macroautophagy GO:0016236 14 8 0,000 9,216E-03 0,028292 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 9,216E-03 0,02825545 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 9,216E-03 0,02821899 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 9,216E-03 0,02818263 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 9,216E-03 0,02814636 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 9,216E-03 0,02811018 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 9,216E-03 0,02807409 ! protein retention in ER lumen GO:0006621 16 8 0,000 9,216E-03 0,0280381 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 9,216E-03 0,0280022 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 9,216E-03 0,02796639 ! regulation of circadian rhythm GO:0042752 13 8 0,000 9,216E-03 0,02793068 ! pigment granule localization GO:0051875 14 8 0,000 9,216E-03 0,02789505 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 9,216E-03 0,02785952 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 9,216E-03 0,02782407 ! response to tropane GO:0014073 14 8 0,000 9,216E-03 0,02778872 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 9,216E-03 0,02775345 ! embryonic axis specification GO:0000578 12 8 0,000 9,216E-03 0,02771828 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 9,216E-03 0,02768319 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 9,216E-03 0,02764819 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 9,216E-03 0,02761328 ! snRNA metabolic process GO:0016073 10 8 0,000 9,216E-03 0,02757846 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 9,216E-03 0,02754373 ! regulation of focal adhesion formation GO:0051893 17 8 0,000 9,216E-03 0,02750908 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 9,216E-03 0,02747452 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 9,216E-03 0,02744005 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 9,216E-03 0,02740566 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 9,216E-03 0,02737136 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 9,216E-03 0,02733715 ! establishment of nucleus localization GO:0040023 14 8 0,000 9,216E-03 0,02730302 ! icosanoid secretion GO:0032309 12 8 0,000 9,216E-03 0,02726898 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 9,216E-03 0,02723502 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 9,216E-03 0,02720114 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 9,216E-03 0,02716735 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 9,216E-03 0,02713365 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 9,216E-03 0,02710002 ! S phase GO:0051320 8 8 0,000 9,216E-03 0,02706648 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 9,216E-03 0,02703303 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 9,216E-03 0,02699965 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 9,216E-03 0,02696636 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 9,216E-03 0,02693315 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 9,216E-03 0,02690002 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 9,216E-03 0,02686698 ! melanin biosynthetic process GO:0042438 11 8 0,000 9,216E-03 0,02683401 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 9,216E-03 0,02680113 ! regulation of synaptogenesis GO:0051963 12 8 0,000 9,216E-03 0,02676832 ! hormone catabolic process GO:0042447 13 8 0,000 9,216E-03 0,0267356 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 9,216E-03 0,02670295 ! quaternary ammonium group transport GO:0015697 10 8 0,000 9,216E-03 0,02667039 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 9,216E-03 0,0266379 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 9,216E-03 0,0266055 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 9,216E-03 0,02657317 ! regulation of telomere maintenance GO:0032204 10 8 0,000 9,216E-03 0,02654092 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 9,216E-03 0,02650875 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 9,216E-03 0,02647666 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 9,216E-03 0,02644464 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 9,216E-03 0,0264127 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 9,216E-03 0,02638084 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 9,216E-03 0,02634906 ! negative regulation of B cell activation GO:0050869 17 8 0,000 9,216E-03 0,02631735 ! behavioral response to nicotine GO:0035095 13 8 0,000 9,216E-03 0,02628572 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 9,216E-03 0,02625417 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 9,216E-03 0,02622269 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 9,216E-03 0,02619128 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 9,216E-03 0,02615995 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 9,216E-03 0,0261287 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01036234 0,02934348 ! regulation of developmental growth GO:0048638 14 9 0,000 0,01036234 0,02930851 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 0,01036234 0,02927362 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01036234 0,02923881 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 0,01036234 0,02920409 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 0,01036234 0,02916944 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 0,01036234 0,02913488 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 0,01036234 0,0291004 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 0,01036234 0,029066 ! cell volume homeostasis GO:0006884 14 9 0,000 0,01036234 0,02903169 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 0,01036234 0,02899745 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 0,01036234 0,0289633 ! UTP metabolic process GO:0046051 10 9 0,000 0,01036234 0,02892922 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 0,01036234 0,02889523 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 0,01036234 0,02886131 ! smoothened signaling pathway GO:0007224 10 9 0,000 0,01036234 0,02882748 ! protein complex disassembly GO:0043241 17 9 0,000 0,01036234 0,02879372 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01036234 0,02876005 ! estrogen metabolic process GO:0008210 16 9 0,000 0,01036234 0,02872645 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01036234 0,02869293 ! photoreceptor cell development GO:0042461 17 9 0,000 0,01036234 0,02865949 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 0,01036234 0,02862612 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 0,01036234 0,02859284 ! microtubule bundle formation GO:0001578 14 9 0,000 0,01036234 0,02855963 ! T-helper 1 type immune response GO:0042088 13 9 0,000 0,01036234 0,0285265 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 0,01036234 0,02849344 ! lung alveolus development GO:0048286 18 9 0,000 0,01036234 0,02846046 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01036234 0,02842756 ! pseudouridine synthesis GO:0001522 10 9 0,000 0,01036234 0,02839473 ! endothelial cell differentiation GO:0045446 17 9 0,000 0,01036234 0,02836198 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01036234 0,02832931 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01036234 0,02829671 ! endoderm development GO:0007492 12 9 0,000 0,01036234 0,02826418 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01036234 0,02823173 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01036234 0,02819936 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 0,01036234 0,02816706 ! astrocyte differentiation GO:0048708 17 9 0,000 0,01036234 0,02813483 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 0,01036234 0,02810267 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 0,01036234 0,02807059 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01036234 0,02803859 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 0,01036234 0,02800665 ! reverse cholesterol transport GO:0043691 17 9 0,000 0,01036234 0,02797479 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 0,01036234 0,027943 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 0,01036234 0,02791128 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 0,01036234 0,02787964 ! macrophage activation GO:0042116 14 9 0,000 0,01036234 0,02784806 ! multicellular organism growth GO:0035264 16 9 0,000 0,01036234 0,02781656 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 0,01036234 0,02778513 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01036234 0,02775377 ! neuron apoptosis GO:0051402 12 9 0,000 0,01036234 0,02772248 ! lens development in camera-type eye GO:0002088 11 9 0,000 0,01036234 0,02769126 ! positive regulation of vasodilation GO:0045909 14 9 0,000 0,01036234 0,02766011 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01036234 0,02762903 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 0,01036234 0,02759802 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01036234 0,02756709 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 0,01036234 0,02753622 ! Schwann cell differentiation GO:0014037 20 9 0,000 0,01036234 0,02750541 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 0,01036234 0,02747468 ! regulation of gliogenesis GO:0014013 21 9 0,000 0,01036234 0,02744402 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 0,01036234 0,02741342 ! oligodendrocyte development GO:0014003 13 9 0,000 0,01036234 0,0273829 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 0,01036234 0,02735244 ! segment specification GO:0007379 11 9 0,000 0,01036234 0,02732204 ! cellular extravasation GO:0045123 12 9 0,000 0,01036234 0,02729172 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01036234 0,02726146 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 0,01036234 0,02723127 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01036234 0,02720115 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01036234 0,02717109 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 0,01036234 0,0271411 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 0,01036234 0,02711118 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 0,01036234 0,02708132 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 0,01036234 0,02705153 ! response to amine stimulus GO:0014075 13 9 0,000 0,01036234 0,0270218 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 0,01036234 0,02699214 ! erythrocyte development GO:0048821 13 9 0,000 0,01036234 0,02696254 ! renal water homeostasis GO:0003091 13 9 0,000 0,01036234 0,02693301 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 0,01036234 0,02690354 ! nucleosome disassembly GO:0006337 13 9 0,000 0,01036234 0,02687414 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 0,01036234 0,0268448 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 0,01036234 0,02681553 ! leukocyte activation during immune response GO:0002366 15 9 0,000 0,01036234 0,02678632 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 0,01036234 0,02675717 ! cerebellum morphogenesis GO:0021587 13 9 0,000 0,01036234 0,02672809 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 0,01036234 0,02669907 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01036234 0,02667011 ! sterol catabolic process GO:0016127 11 9 0,000 0,01036234 0,02664121 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 0,01036234 0,02661238 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01036234 0,02658361 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 0,01036234 0,0265549 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 0,01036234 0,02652626 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 0,01036234 0,02649767 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 0,01036234 0,02646915 ! prophase GO:0051324 12 9 0,000 0,01036234 0,02644069 ! neuroblast proliferation GO:0007405 19 9 0,000 0,01036234 0,02641229 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 0,01036234 0,02638395 ! peptidyl-threonine modification GO:0018210 22 9 0,000 0,01036234 0,02635567 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 0,01036234 0,02632745 ! ubiquinone metabolic process GO:0006743 11 9 0,000 0,01036234 0,02629929 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 0,01036234 0,0262712 ! acid secretion GO:0046717 14 9 0,000 0,01036234 0,02624316 ! purine base metabolic process GO:0006144 18 9 0,000 0,01036234 0,02621518 ! detection of calcium ion GO:0005513 13 9 0,000 0,01036234 0,02618726 ! myeloid cell homeostasis GO:0002262 10 9 0,000 0,01036234 0,0261594 ! regulation of fibrinolysis GO:0051917 14 9 0,000 0,01036234 0,0261316 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01036234 0,02610386 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 0,01036234 0,02607618 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 0,01036234 0,02604856 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01036234 0,02602099 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01036234 0,02599349 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 0,01036234 0,02596604 ! prepulse inhibition GO:0060134 14 9 0,000 0,01036234 0,02593865 ! sequestering of metal ion GO:0051238 12 9 0,000 0,01036234 0,02591132 ! lamellipodium assembly GO:0030032 12 9 0,000 0,01036234 0,02588404 ! regulation of embryonic development GO:0045995 17 9 0,000 0,01036234 0,02585682 ! mitochondrion localization GO:0051646 15 9 0,000 0,01036234 0,02582966 ! localization within membrane GO:0051668 15 9 0,000 0,01036234 0,02580256 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01150735 0,02862364 ! axon extension GO:0048675 13 10 0,000 0,01150735 0,02859367 ! neuron fate specification GO:0048665 12 10 0,000 0,01150735 0,02856376 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,01150735 0,02853391 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,01150735 0,02850412 ! associative learning GO:0008306 19 10 0,000 0,01150735 0,0284744 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,01150735 0,02844474 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01150735 0,02841514 ! CTP metabolic process GO:0046036 11 10 0,000 0,01150735 0,0283856 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,01150735 0,02835613 ! GTP metabolic process GO:0046039 11 10 0,000 0,01150735 0,02832671 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01150735 0,02829736 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,01150735 0,02826806 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01150735 0,02823883 ! social behavior GO:0035176 15 10 0,000 0,01150735 0,02820966 ! sulfate transport GO:0008272 12 10 0,000 0,01150735 0,02818055 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,01150735 0,0281515 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,01150735 0,0281225 ! artery development GO:0060840 20 10 0,000 0,01150735 0,02809357 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,01150735 0,0280647 ! response to pain GO:0048265 20 10 0,000 0,01150735 0,02803588 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,01150735 0,02800713 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,01150735 0,02797843 ! phospholipid efflux GO:0033700 17 10 0,000 0,01150735 0,0279498 ! hippocampus development GO:0021766 19 10 0,000 0,01150735 0,02792122 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,01150735 0,0278927 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,01150735 0,02786423 ! blood vessel remodeling GO:0001974 23 10 0,000 0,01150735 0,02783583 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01150735 0,02780748 ! pathogenesis GO:0009405 13 10 0,000 0,01150735 0,0277792 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01150735 0,02775097 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,01150735 0,02772279 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,01150735 0,02769468 ! protein targeting to ER GO:0045047 21 10 0,000 0,01150735 0,02766662 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,01150735 0,02763861 ! arginine catabolic process GO:0006527 12 10 0,000 0,01150735 0,02761067 ! melanocyte differentiation GO:0030318 16 10 0,000 0,01150735 0,02758278 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,01150735 0,02755494 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01150735 0,02752717 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 0,000 0,01150735 0,02749945 ! regulation of stress fiber formation GO:0051492 24 10 0,000 0,01150735 0,02747178 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,01150735 0,02744417 ! B cell proliferation GO:0042100 16 10 0,000 0,01150735 0,02741662 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,01150735 0,02738912 ! mannose metabolic process GO:0006013 11 10 0,000 0,01150735 0,02736167 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01150735 0,02733428 ! forebrain cell migration GO:0021885 17 10 0,000 0,01150735 0,02730695 ! lipid digestion GO:0044241 15 10 0,000 0,01150735 0,02727967 ! substrate-bound cell migration GO:0006929 11 10 0,000 0,01150735 0,02725245 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01150735 0,02722527 ! receptor clustering GO:0043113 18 10 0,000 0,01150735 0,02719816 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01150735 0,02717109 ! UV protection GO:0009650 14 10 0,000 0,01150735 0,02714409 ! entry into host cell GO:0030260 21 10 0,000 0,01150735 0,02711713 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,01150735 0,02709023 ! behavioral fear response GO:0001662 19 10 0,000 0,01150735 0,02706338 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01150735 0,02703658 ! negative regulation of ossification GO:0030279 21 10 0,000 0,01150735 0,02700984 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,01150735 0,02698315 ! protein homotetramerization GO:0051289 20 10 0,000 0,01150735 0,02695652 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,01150735 0,02692993 ! response to dsRNA GO:0043331 19 10 0,000 0,01150735 0,0269034 ! DNA ligation GO:0006266 16 10 0,000 0,01150735 0,02687692 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,01150735 0,02685049 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,01150735 0,02682412 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01150735 0,02679779 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01150735 0,02677152 ! positive regulation of Ras GTPase activity GO:0032320 24 10 0,000 0,01150735 0,0267453 ! postreplication repair GO:0006301 16 10 0,000 0,01150735 0,02671913 ! fucose catabolic process GO:0019317 17 10 0,000 0,01150735 0,02669301 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,01150735 0,02666694 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01150735 0,02664093 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,01150735 0,02661496 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,01150735 0,02658905 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,01150735 0,02656318 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01150735 0,02653737 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,01150735 0,0265116 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,01150735 0,02648589 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,01150735 0,02646022 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,01150735 0,02643461 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,01150735 0,02640904 ! oocyte differentiation GO:0009994 14 10 0,000 0,01150735 0,02638353 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,01150735 0,02635806 ! spleen development GO:0048536 17 10 0,000 0,01150735 0,02633264 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,01150735 0,02630727 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,01150735 0,02628195 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 0,01150735 0,02625668 ! blastocyst formation GO:0001825 14 10 0,000 0,01150735 0,02623146 ! embryonic gut development GO:0048566 13 10 0,000 0,01150735 0,02620629 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,01150735 0,02618116 ! cerebellar cortex development GO:0021695 14 10 0,000 0,01150735 0,02615608 ! activation of innate immune response GO:0002218 10 10 0,000 0,01150735 0,02613105 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01150735 0,02610607 ! insulin secretion GO:0030073 18 10 0,000 0,01150735 0,02608114 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 0,01150735 0,02605625 ! response to nicotine GO:0035094 18 10 0,000 0,01150735 0,02603141 ! establishment of cell polarity GO:0030010 12 10 0,000 0,01150735 0,02600662 ! nucleus localization GO:0051647 16 10 0,000 0,01150735 0,02598187 ! regulation of synapse organization GO:0050807 14 10 0,000 0,01150735 0,02595718 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,0126511 0,02851002 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,0126511 0,02848297 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,0126511 0,02845597 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,0126511 0,02842903 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,0126511 0,02840213 ! virus-host interaction GO:0019048 20 11 0,000 0,0126511 0,02837529 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,0126511 0,02834849 GO:0006740|NADPH regeneration, ! regulation of phosphatase activity GO:0010921 23 11 0,000 0,0126511 0,02832175 ! non-recombinational repair GO:0000726 19 11 0,000 0,0126511 0,02829505 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,0126511 0,02826841 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,0126511 0,02824182 ! Golgi vesicle budding GO:0048194 18 11 0,000 0,0126511 0,02821528 ! elastic fiber assembly GO:0048251 17 11 0,000 0,0126511 0,02818878 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,0126511 0,02816234 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,0126511 0,02813594 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,0126511 0,0281096 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,0126511 0,02808331 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,0126511 0,02805706 ! bone resorption GO:0045453 16 11 0,000 0,0126511 0,02803086 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,0126511 0,02800471 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,0126511 0,02797861 ! ventral spinal cord development GO:0021517 15 11 0,000 0,0126511 0,02795256 ! regulated secretory pathway GO:0045055 15 11 0,000 0,0126511 0,02792656 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 0,0126511 0,02790061 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,0126511 0,0278747 ! syncytium formation GO:0006949 15 11 0,000 0,0126511 0,02784884 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,0126511 0,02782303 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,0126511 0,02779727 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,0126511 0,02777156 ! Golgi organization GO:0007030 19 11 0,000 0,0126511 0,02774589 ! response to X-ray GO:0010165 19 11 0,000 0,0126511 0,02772027 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,0126511 0,0276947 ! adult heart development GO:0007512 12 11 0,000 0,0126511 0,02766917 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,0126511 0,0276437 ! epithelial cell development GO:0002064 16 11 0,000 0,0126511 0,02761826 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,0126511 0,02759288 ! temperature homeostasis GO:0001659 16 11 0,000 0,0126511 0,02756754 ! L-glutamate transport GO:0015813 15 11 0,000 0,0126511 0,02754225 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,0126511 0,02751701 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,0126511 0,02749181 ! motor axon guidance GO:0008045 17 11 0,000 0,0126511 0,02746665 ! copper ion homeostasis GO:0055070 15 11 0,000 0,0126511 0,02744155 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,0126511 0,02741649 ! regulation of bone resorption GO:0045124 27 11 0,000 0,0126511 0,02739147 ! stem cell development GO:0048864 30 11 0,000 0,0126511 0,0273665 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,0126511 0,02734158 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,0126511 0,0273167 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,0126511 0,02729187 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,0126511 0,02726708 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0126511 0,02724234 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,0126511 0,02721764 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,0126511 0,02719298 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,0126511 0,02716837 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,0126511 0,02714381 ! cranial nerve development GO:0021545 14 11 0,000 0,0126511 0,02711929 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0126511 0,02709481 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0126511 0,02707038 ! salivary gland development GO:0007431 24 11 0,000 0,0126511 0,02704599 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,0126511 0,02702165 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,0126511 0,02699735 ! musculoskeletal movement GO:0050881 16 11 0,000 0,0126511 0,02697309 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,0126511 0,02694888 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,0126511 0,02692471 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,0126511 0,02690059 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 20 11 0,000 0,0126511 0,0268765 ! digestive tract morphogenesis GO:0048546 16 11 0,000 0,0126511 0,02685246 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,0126511 0,02682847 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,0126511 0,02680451 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 0,0126511 0,0267806 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,0126511 0,02675673 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,0126511 0,02673291 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,0126511 0,02670912 ! regulation of actin filament bundle formation GO:0032231 25 11 0,000 0,0126511 0,02668538 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,0126511 0,02666168 ! defense response to fungus GO:0050832 13 11 0,000 0,0126511 0,02663802 ! lysogeny GO:0030069 20 11 0,000 0,0126511 0,02661441 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,0126511 0,02659084 ! acrosome reaction GO:0007340 14 11 0,000 0,0126511 0,0265673 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,0126511 0,02654381 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,0126511 0,02652037 ! rRNA transcription GO:0009303 19 12 0,000 0,01379357 0,02888981 ! reproductive cellular process GO:0048610 15 12 0,000 0,01379357 0,02886433 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01379357 0,0288389 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01379357 0,02881351 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01379357 0,02878817 ! phosphate transport GO:0006817 15 12 0,000 0,01379357 0,02876288 ! positive regulation of GTPase activity GO:0043547 29 12 0,000 0,01379357 0,02873762 ! peroxisomal transport GO:0043574 22 12 0,000 0,01379357 0,02871241 ! mating GO:0007618 16 12 0,000 0,01379357 0,02868725 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01379357 0,02866213 ! heart looping GO:0001947 15 12 0,000 0,01379357 0,02863705 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01379357 0,02861202 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01379357 0,02858703 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01379357 0,02856209 ! T cell selection GO:0045058 25 12 0,000 0,01379357 0,02853719 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01379357 0,02851233 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,01379357 0,02848751 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01379357 0,02846274 ! plasma membrane organization GO:0007009 19 12 0,000 0,01379357 0,02843801 ! focal adhesion formation GO:0048041 28 12 0,000 0,01379357 0,02841333 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01379357 0,02838868 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01379357 0,02836408 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01379357 0,02833953 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01379357 0,02831501 ! monoamine transport GO:0015844 14 12 0,000 0,01379357 0,02829054 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01379357 0,02826611 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01379357 0,02824172 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01379357 0,02821737 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01379357 0,02819307 ! regulation of organ growth GO:0046620 14 12 0,000 0,01379357 0,02816881 ! vasoconstriction GO:0042310 18 12 0,000 0,01379357 0,02814458 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01379357 0,02812041 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01379357 0,02809627 ! regulation of Rho GTPase activity GO:0032319 22 12 0,000 0,01379357 0,02807217 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01379357 0,02804812 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01379357 0,0280241 ! histone deacetylation GO:0016575 14 12 0,000 0,01379357 0,02800013 ! histone acetylation GO:0016573 27 12 0,000 0,01379357 0,0279762 ! DNA methylation GO:0006306 19 12 0,000 0,01379357 0,02795231 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,01379357 0,02792846 ! protein sumoylation GO:0016925 14 12 0,000 0,01379357 0,02790465 ! chromatin silencing GO:0006342 23 12 0,000 0,01379357 0,02788088 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01379357 0,02785715 ! gland morphogenesis GO:0022612 24 12 0,000 0,01379357 0,02783346 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01379357 0,02780982 ! zymogen activation GO:0031638 16 12 0,000 0,01379357 0,02778621 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01379357 0,02776264 ! nucleosome positioning GO:0016584 13 12 0,000 0,01379357 0,02773911 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01379357 0,02771562 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01379357 0,02769218 ! response to gamma radiation GO:0010332 21 12 0,000 0,01379357 0,02766877 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01379357 0,0276454 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01379357 0,02762207 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01379357 0,02759878 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01379357 0,02757553 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01379357 0,02755232 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01379357 0,02752914 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01379357 0,02750601 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01379357 0,02748292 ! embryonic placenta development GO:0001892 15 12 0,000 0,01379357 0,02745986 ! response to cold GO:0009409 15 12 0,000 0,01379357 0,02743684 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01379357 0,02741386 ! respiratory burst GO:0045730 22 13 0,000 0,01493479 0,02965711 ! lactation GO:0007595 22 13 0,000 0,01493479 0,02963232 ! tRNA modification GO:0006400 15 13 0,000 0,01493479 0,02960756 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,01493479 0,02958285 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,01493479 0,02955817 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01493479 0,02953354 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,01493479 0,02950895 ! water transport GO:0006833 21 13 0,000 0,01493479 0,0294844 GO:0042044|fluid transport, ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,01493479 0,02945989 ! copper ion transport GO:0006825 15 13 0,000 0,01493479 0,02943542 ! filopodium assembly GO:0046847 21 13 0,000 0,01493479 0,029411 ! lipid localization GO:0010876 25 13 0,000 0,01493479 0,02938661 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,01493479 0,02936226 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,01493479 0,02933796 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,01493479 0,02931369 ! T cell proliferation GO:0042098 24 13 0,000 0,01493479 0,02928946 ! organelle fusion GO:0048284 29 13 0,000 0,01493479 0,02926528 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01493479 0,02924113 ! endocrine pancreas development GO:0031018 19 13 0,000 0,01493479 0,02921702 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,01493479 0,02919296 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,01493479 0,02916893 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,01493479 0,02914494 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,01493479 0,02912099 ! methionine metabolic process GO:0006555 16 13 0,000 0,01493479 0,02909709 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,01493479 0,02907322 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01493479 0,02904939 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,01493479 0,02902559 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,01493479 0,02900184 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,01493479 0,02897813 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,01493479 0,02895445 ! neutral amino acid transport GO:0015804 20 13 0,000 0,01493479 0,02893082 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,01493479 0,02890722 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,01493479 0,02888366 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,01493479 0,02886014 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,01493479 0,02883666 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01493479 0,02881321 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01493479 0,02878981 ! cellular pigmentation GO:0033059 24 13 0,000 0,01493479 0,02876644 ! histone methylation GO:0016571 16 13 0,000 0,01493479 0,02874311 ! regulation of epidermis development GO:0045682 21 13 0,000 0,01493479 0,02871981 ! oxygen transport GO:0015671 20 13 0,000 0,01493479 0,02869656 ! regulation of axon extension GO:0030516 26 13 0,000 0,01493479 0,02867334 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,01493479 0,02865016 ! detection of bacterium GO:0016045 13 13 0,000 0,01493479 0,02862702 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,01493479 0,02860391 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,01493479 0,02858085 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,01493479 0,02855782 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,01493479 0,02853482 ! actin filament polymerization GO:0030041 18 13 0,000 0,01493479 0,02851187 ! regulation of protein ubiquitination GO:0031396 20 14 0,000 0,01607474 0,03066347 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,01607474 0,03063884 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,01607474 0,03061425 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,01607474 0,0305897 ! neuron maturation GO:0042551 24 14 0,000 0,01607474 0,03056519 ! regulation of S phase GO:0033261 25 14 0,000 0,01607474 0,03054071 ! regulation of chemokine production GO:0032642 18 14 0,000 0,01607474 0,03051628 ! myotube differentiation GO:0014902 21 14 0,000 0,01607474 0,03049189 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,01607474 0,03046753 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,01607474 0,03044322 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,01607474 0,03041894 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,01607474 0,0303947 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,01607474 0,0303705 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,01607474 0,03034634 ! RNA polyadenylation GO:0043631 21 14 0,000 0,01607474 0,03032222 ! cartilage condensation GO:0001502 22 14 0,000 0,01607474 0,03029813 ! gene silencing by RNA GO:0031047 22 14 0,000 0,01607474 0,03027409 ! response to cAMP GO:0051591 20 14 0,000 0,01607474 0,03025008 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,01607474 0,03022611 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,01607474 0,03020218 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,01607474 0,03017828 ! limbic system development GO:0021761 25 14 0,000 0,01607474 0,03015443 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,01607474 0,03013061 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,01607474 0,03010683 ! palate development GO:0060021 19 14 0,000 0,01607474 0,03008308 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,01607474 0,03005938 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,01607474 0,03003571 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,01607474 0,03001208 ! response to hexose stimulus GO:0009746 22 14 0,000 0,01607474 0,02998848 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,01607474 0,02996493 ! arginine metabolic process GO:0006525 17 14 0,000 0,01607474 0,02994141 ! glutamate metabolic process GO:0006536 21 14 0,000 0,01607474 0,02991792 ! glycine metabolic process GO:0006544 22 14 0,000 0,01607474 0,02989448 ! pituitary gland development GO:0021983 24 14 0,000 0,01607474 0,02987107 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,01607474 0,02984769 ! lysosomal transport GO:0007041 21 14 0,000 0,01607474 0,02982436 ! cytokine metabolic process GO:0042107 18 14 0,000 0,01607474 0,02980106 ! NAD metabolic process GO:0019674 25 14 0,000 0,01607474 0,02977779 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,01607474 0,02975456 ! regulation of heart rate GO:0002027 26 14 0,000 0,01607474 0,02973137 ! exocrine system development GO:0035272 29 14 0,000 0,01607474 0,02970822 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,01607474 0,0296851 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,01607474 0,02966201 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,01607474 0,02963897 ! axon cargo transport GO:0008088 29 14 0,000 0,01607474 0,02961596 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,01607474 0,02959298 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,01607474 0,02957004 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,01607474 0,02954713 ! autonomic nervous system development GO:0048483 26 14 0,000 0,01607474 0,02952427 ! tissue regeneration GO:0042246 24 14 0,000 0,01607474 0,02950143 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,01607474 0,02947863 ! water homeostasis GO:0030104 23 14 0,000 0,01607474 0,02945587 ! cofactor transport GO:0051181 22 14 0,000 0,01607474 0,02943314 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,01607474 0,02941045 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,01607474 0,02938779 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01607474 0,02936517 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01607474 0,02934258 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,01607474 0,02932002 ! cell killing GO:0001906 22 14 0,000 0,01607474 0,0292975 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,01607474 0,02927502 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,01607474 0,02925257 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,01607474 0,02923015 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,01607474 0,02920777 ! microspike assembly GO:0030035 25 14 0,000 0,01607474 0,02918543 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,01607474 0,02916311 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,01721342 0,03120509 ! superoxide anion generation GO:0042554 19 15 0,000 0,01721342 0,03118127 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,01721342 0,03115748 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,01721342 0,03113373 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,01721342 0,03111002 ! inositol metabolic process GO:0006020 21 15 0,000 0,01721342 0,03108634 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,01721342 0,03106271 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,01721342 0,0310391 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,01721342 0,03101553 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,01721342 0,030992 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01721342 0,0309685 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,01721342 0,03094504 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,01721342 0,03092162 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,01721342 0,03089823 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01721342 0,03087487 ! response to osmotic stress GO:0006970 23 15 0,000 0,01721342 0,03085155 ! vesicle coating GO:0006901 26 15 0,000 0,01721342 0,03082827 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,01721342 0,03080502 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,01721342 0,03078181 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,01721342 0,03075863 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,01721342 0,03073548 ! bone mineralization GO:0030282 17 15 0,000 0,01721342 0,03071237 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,01721342 0,0306893 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,01721342 0,03066626 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,01721342 0,03064325 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,01721342 0,03062028 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,01721342 0,03059735 ! regulation of cellular pH GO:0030641 23 15 0,000 0,01721342 0,03057444 ! ribosome assembly GO:0042255 17 15 0,000 0,01721342 0,03055158 ! cerebellum development GO:0021549 19 15 0,000 0,01721342 0,03052874 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,01721342 0,03050594 ! mRNA splice site selection GO:0006376 33 15 0,000 0,01721342 0,03048318 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,01721342 0,03046045 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,01721342 0,03043775 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,01721342 0,03041508 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,01721342 0,03039245 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,01721342 0,03036986 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,01721342 0,03034729 ! muscle maintenance GO:0046716 21 15 0,000 0,01721342 0,03032476 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,01721342 0,03030227 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,01721342 0,03027981 ! intestinal absorption GO:0050892 22 15 0,000 0,01721342 0,03025738 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,01721342 0,03023498 ! dopamine metabolic process GO:0042417 32 15 0,000 0,01721342 0,03021262 ! gas transport GO:0015669 23 15 0,000 0,01721342 0,03019029 ! regulation of RNA stability GO:0043487 31 15 0,000 0,01721342 0,03016799 ! organic cation transport GO:0015695 19 15 0,000 0,01721342 0,03014572 ! heme biosynthetic process GO:0006783 22 15 0,000 0,01721342 0,03012349 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,01721342 0,03010129 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,01721342 0,03007913 ! cilium assembly GO:0042384 22 15 0,000 0,01721342 0,030057 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,01721342 0,0300349 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,01721342 0,03001283 ! peptide hormone processing GO:0016486 23 15 0,000 0,01721342 0,02999079 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,01835085 0,03194906 ! bone remodeling GO:0046849 24 16 0,000 0,01835085 0,03192564 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,01835085 0,03190225 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,01835085 0,0318789 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,01835085 0,03185558 ! bile acid metabolic process GO:0008206 23 16 0,000 0,01835085 0,03183229 ! axis specification GO:0009798 26 16 0,000 0,01835085 0,03180904 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,01835085 0,03178582 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,01835085 0,03176263 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01835085 0,03173948 ! centrosome cycle GO:0007098 18 16 0,000 0,01835085 0,03171637 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,01835085 0,03169328 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,01835085 0,03167023 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,01835085 0,03164722 ! cellular response to starvation GO:0009267 26 16 0,000 0,01835085 0,03162424 ! DNA integration GO:0015074 25 16 0,000 0,01835085 0,03160129 ! embryo implantation GO:0007566 35 16 0,000 0,01835085 0,03157837 ! regulation of exocytosis GO:0017157 28 16 0,000 0,01835085 0,03155549 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,01835085 0,03153264 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,01835085 0,03150982 ! regulation of vasodilation GO:0042312 26 16 0,000 0,01835085 0,03148704 ! DNA replication initiation GO:0006270 26 16 0,000 0,01835085 0,03146429 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,01835085 0,03144157 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,01835085 0,03141888 ! neuron recognition GO:0008038 27 16 0,000 0,01835085 0,03139623 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,01835085 0,03137361 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,01835085 0,03135102 ! G1 phase GO:0051318 28 16 0,000 0,01835085 0,03132847 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,01835085 0,03130595 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01835085 0,03128346 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,01835085 0,031261 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,01835085 0,03123857 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,01835085 0,03121618 ! NADP metabolic process GO:0006739 22 16 0,000 0,01835085 0,03119382 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,01835085 0,03117149 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,01835085 0,03114919 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,01835085 0,03112693 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,01835085 0,03110469 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01835085 0,03108249 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,01835085 0,03106032 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,01835085 0,03103818 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,01835085 0,03101608 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,01835085 0,030994 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,01835085 0,03097196 ! defense response to virus GO:0051607 28 16 0,000 0,01835085 0,03094994 ! peptide hormone secretion GO:0030072 26 16 0,000 0,01835085 0,03092796 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,01948702 0,03281952 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,01948702 0,03279624 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,01948702 0,032773 ! zinc ion transport GO:0006829 22 17 0,000 0,01948702 0,03274979 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01948702 0,03272661 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,01948702 0,03270346 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,01948702 0,03268035 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,01948702 0,03265727 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,01948702 0,03263423 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,01948702 0,03261121 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,01948702 0,03258823 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,01948702 0,03256528 ! adult walking behavior GO:0007628 30 17 0,000 0,01948702 0,03254236 ! patterning of blood vessels GO:0001569 27 17 0,000 0,01948702 0,03251948 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,01948702 0,03249663 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,01948702 0,03247381 GO:0042744|hydrogen peroxide catabolic process, ! retinoid metabolic process GO:0001523 22 17 0,000 0,01948702 0,03245102 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,01948702 0,03242826 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,01948702 0,03240554 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,01948702 0,03238284 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01948702 0,03236018 ! protein polyubiquitination GO:0000209 31 17 0,000 0,01948702 0,03233755 ! cerebral cortex development GO:0021987 34 17 0,000 0,01948702 0,03231495 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,01948702 0,03229239 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01948702 0,03226985 ! fructose metabolic process GO:0006000 24 17 0,000 0,01948702 0,03224735 ! membrane budding GO:0006900 30 17 0,000 0,01948702 0,03222488 ! neuromuscular junction development GO:0007528 25 17 0,000 0,01948702 0,03220244 ! L-amino acid transport GO:0015807 27 17 0,000 0,01948702 0,03218003 ! regulation of protein binding GO:0043393 29 17 0,000 0,01948702 0,03215765 ! peptide secretion GO:0002790 30 17 0,000 0,01948702 0,0321353 ! stem cell differentiation GO:0048863 40 17 0,000 0,01948702 0,03211299 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01948702 0,0320907 ! intermediate filament-based process GO:0045103 29 17 0,000 0,01948702 0,03206845 ! protein export from nucleus GO:0006611 26 17 0,000 0,01948702 0,03204622 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,01948702 0,03202403 ! diencephalon development GO:0021536 27 17 0,000 0,01948702 0,03200187 ! oogenesis GO:0048477 25 17 0,000 0,01948702 0,03197974 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,01948702 0,03195764 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,01948702 0,03193557 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01948702 0,03191353 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,01948702 0,03189152 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,01948702 0,03186954 ! steroid catabolic process GO:0006706 24 17 0,000 0,01948702 0,03184759 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,01948702 0,03182567 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,01948702 0,03180378 ! nerve development GO:0021675 20 17 0,000 0,01948702 0,03178192 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,01948702 0,0317601 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,01948702 0,0317383 ! protein secretion GO:0009306 32 18 0,000 0,02062193 0,03356368 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,02062193 0,03354067 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,02062193 0,0335177 ! negative regulation of defense response GO:0031348 21 18 0,000 0,02062193 0,03349476 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,02062193 0,03347185 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,02062193 0,03344897 ! metencephalon development GO:0022037 25 18 0,000 0,02062193 0,03342612 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,02062193 0,0334033 ! hormone secretion GO:0046879 28 18 0,000 0,02062193 0,03338052 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,02062193 0,03335776 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,02062193 0,03333504 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,02062193 0,03331235 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02062193 0,03328969 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,02062193 0,03326706 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,02062193 0,03324446 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02062193 0,03322189 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,02062193 0,03319935 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,02062193 0,03317684 ! glial cell development GO:0021782 31 18 0,000 0,02062193 0,03315436 ! keratinization GO:0031424 19 18 0,000 0,02062193 0,03313192 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,02062193 0,0331095 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,02062193 0,03308711 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,02062193 0,03306476 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,02062193 0,03304243 ! vacuolar transport GO:0007034 26 18 0,000 0,02062193 0,03302014 ! pigmentation during development GO:0048066 35 18 0,000 0,02062193 0,03299787 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,02062193 0,03297563 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,02062193 0,03295343 ! fucose metabolic process GO:0006004 27 18 0,000 0,02062193 0,03293125 ! actin filament bundle formation GO:0051017 30 18 0,000 0,02062193 0,03290911 ! body fluid secretion GO:0007589 27 18 0,000 0,02062193 0,03288699 ! regulation of dephosphorylation GO:0035303 38 18 0,000 0,02062193 0,0328649 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,02062193 0,03284285 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,02062193 0,03282082 ! negative regulation of immune response GO:0050777 33 18 0,000 0,02062193 0,03279882 ! heart process GO:0003015 32 18 0,000 0,02062193 0,03277685 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,02062193 0,03275491 ! sensory perception of pain GO:0019233 26 18 0,000 0,02062193 0,032733 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,02062193 0,03271112 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,02062193 0,03268927 ! somitogenesis GO:0001756 25 18 0,000 0,02062193 0,03266745 ! neural crest cell migration GO:0001755 28 18 0,000 0,02062193 0,03264566 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,02062193 0,03262389 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,02062193 0,03260216 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,02062193 0,03258045 ! synaptogenesis GO:0007416 28 18 0,000 0,02062193 0,03255878 ! cell-cell junction organization GO:0045216 28 18 0,000 0,02062193 0,03253713 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02062193 0,03251551 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,02062193 0,03249392 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,02062193 0,03247236 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,02062193 0,03245082 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,02062193 0,03242932 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,02062193 0,03240784 ! gut development GO:0048565 29 18 0,000 0,02062193 0,03238639 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,02062193 0,03236497 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,02062193 0,03234358 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,02062193 0,03232222 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,02175558 0,03407657 ! positive regulation of translation GO:0045727 29 19 0,000 0,02175558 0,03405409 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,02175558 0,03403164 ! glycerol metabolic process GO:0006071 22 19 0,000 0,02175558 0,03400922 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,02175558 0,03398683 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,02175558 0,03396447 ! endothelial cell migration GO:0043542 24 19 0,000 0,02175558 0,03394214 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,02175558 0,03391984 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,02175558 0,03389757 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,02175558 0,03387533 ! memory GO:0007613 28 19 0,000 0,02175558 0,03385311 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,02175558 0,03383093 ! pancreas development GO:0031016 27 19 0,000 0,02175558 0,03380878 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,02175558 0,03378665 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,02175558 0,03376455 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,02175558 0,03374248 ! central nervous system neuron development GO:0021954 33 19 0,000 0,02175558 0,03372044 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,02175558 0,03369843 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,02175558 0,03367645 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,02175558 0,0336545 ! heme metabolic process GO:0042168 29 19 0,000 0,02175558 0,03363257 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,02175558 0,03361068 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,02175558 0,03358881 ! response to fungus GO:0009620 21 19 0,000 0,02175558 0,03356697 ! peptide cross-linking GO:0018149 35 19 0,000 0,02175558 0,03354516 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,02175558 0,03352338 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,02175558 0,03350162 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,02175558 0,0334799 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,02175558 0,0334582 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,02175558 0,03343653 ! vitamin transport GO:0051180 26 19 0,000 0,02175558 0,03341489 ! sarcomere organization GO:0045214 26 19 0,000 0,02175558 0,03339327 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,02175558 0,03337169 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,02175558 0,03335013 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,02175558 0,0333286 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,02175558 0,0333071 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,02175558 0,03328562 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,02175558 0,03326418 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,02288798 0,03497307 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,02288798 0,03495057 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,02288798 0,03492809 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,02288798 0,03490564 ! lipid phosphorylation GO:0046834 28 20 0,000 0,02288798 0,03488323 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,02288798 0,03486084 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,02288798 0,03483847 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,02288798 0,03481614 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,02288798 0,03479384 ! response to alkaloid GO:0043279 34 20 0,000 0,02288798 0,03477156 ! sensory perception of taste GO:0050909 26 20 0,000 0,02288798 0,03474932 ! response to retinoic acid GO:0032526 27 20 0,000 0,02288798 0,0347271 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,02288798 0,03470491 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,02288798 0,03468275 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,02288798 0,03466061 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,02288798 0,03463851 ! chromosome condensation GO:0030261 32 20 0,000 0,02288798 0,03461643 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,02288798 0,03459438 ! sex determination GO:0007530 32 20 0,000 0,02288798 0,03457236 ! plasma membrane fusion GO:0045026 24 20 0,000 0,02288798 0,03455037 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,02288798 0,03452841 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,02288798 0,03450647 ! cytolysis GO:0019835 21 20 0,000 0,02288798 0,03448456 ! renal system process GO:0003014 35 20 0,000 0,02288798 0,03446268 ! vasodilation GO:0042311 36 20 0,000 0,02288798 0,03444083 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,02288798 0,034419 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,02288798 0,0343972 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,02288798 0,03437543 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,02288798 0,03435369 ! hormone transport GO:0009914 30 20 0,000 0,02288798 0,03433197 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,02288798 0,03431029 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,02288798 0,03428862 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,02288798 0,03426699 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,02288798 0,03424539 ! sperm-egg recognition GO:0035036 24 20 0,000 0,02288798 0,03422381 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,02288798 0,03420226 ! negative regulation of translation GO:0017148 28 20 0,000 0,02288798 0,03418073 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,02288798 0,03415923 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,02401913 0,03582488 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02401913 0,03580238 ! positive regulation of ossification GO:0045778 34 21 0,000 0,02401913 0,0357799 ! iron ion transport GO:0006826 49 21 0,000 0,02401913 0,03575746 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,02401913 0,03573504 ! microtubule-based transport GO:0010970 41 21 0,000 0,02401913 0,03571265 ! vesicle docking GO:0048278 28 21 0,000 0,02401913 0,03569029 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,02401913 0,03566795 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,02401913 0,03564565 ! response to ethanol GO:0045471 38 21 0,000 0,02401913 0,03562337 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,02401913 0,03560112 ! smooth muscle contraction GO:0006939 39 21 0,000 0,02401913 0,03557889 ! glutamine metabolic process GO:0006541 29 21 0,000 0,02401913 0,0355567 ! response to vitamin A GO:0033189 28 21 0,000 0,02401913 0,03553453 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,02401913 0,03551239 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,02401913 0,03549028 ! apoptotic nuclear changes GO:0030262 31 21 0,000 0,02401913 0,03546819 ! response to starvation GO:0042594 35 21 0,000 0,02401913 0,03544614 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,02401913 0,03542411 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,02401913 0,0354021 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,02401913 0,03538013 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,02401913 0,03535818 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,02401913 0,03533626 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,02401913 0,03531437 ! visual learning GO:0008542 38 21 0,000 0,02401913 0,0352925 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,02401913 0,03527066 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,02401913 0,03524885 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02401913 0,03522706 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,02401913 0,0352053 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,02401913 0,03518357 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02401913 0,03516187 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,02401913 0,03514019 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,02401913 0,03511854 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02401913 0,03509691 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,02401913 0,03507532 ! embryonic pattern specification GO:0009880 34 22 0,000 0,02514902 0,03670272 ! regulation of cell killing GO:0031341 37 22 0,000 0,02514902 0,03668016 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,02514902 0,03665763 ! gluconeogenesis GO:0006094 26 22 0,000 0,02514902 0,03663513 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,02514902 0,03661265 ! viral genome replication GO:0019079 31 22 0,000 0,02514902 0,0365902 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,02514902 0,03656778 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,02514902 0,03654539 ! protein amino acid acylation GO:0043543 42 22 0,000 0,02514902 0,03652302 ! response to vitamin GO:0033273 31 22 0,000 0,02514902 0,03650069 ! molting cycle process GO:0022404 43 22 0,000 0,02514902 0,03647837 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,02514902 0,03645609 ! regeneration GO:0031099 37 22 0,000 0,02514902 0,03643383 ! phototransduction GO:0007602 29 22 0,000 0,02514902 0,0364116 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,02514902 0,0363894 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,02514902 0,03636723 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,02514902 0,03634508 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,02514902 0,03632296 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,02514902 0,03630086 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,02514902 0,0362788 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,02514902 0,03625676 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,02514902 0,03623474 ! pallium development GO:0021543 43 22 0,000 0,02514902 0,03621275 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,02514902 0,03619079 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,02514902 0,03616886 ! platelet activation GO:0030168 33 22 0,000 0,02514902 0,03614695 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,02514902 0,03612507 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,02514902 0,03610322 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,02514902 0,03608139 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,02514902 0,03605959 ! cell-cell recognition GO:0009988 28 22 0,000 0,02514902 0,03603781 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,02514902 0,03601607 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,02514902 0,03599434 ! neural tube closure GO:0001843 35 22 0,000 0,02514902 0,03597265 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,02514902 0,03595098 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,02514902 0,03592933 ! protein tetramerization GO:0051262 43 22 0,000 0,02514902 0,03590771 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,02627766 0,03749662 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,02627766 0,03747409 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,02627766 0,03745158 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,02627766 0,0374291 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,02627766 0,03740665 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,02627766 0,03738422 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,02627766 0,03736182 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,02627766 0,03733945 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,02627766 0,03731711 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,02627766 0,03729479 ! tube lumen formation GO:0035148 37 23 0,000 0,02627766 0,03727249 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,02627766 0,03725023 ! dendrite development GO:0016358 41 23 0,000 0,02627766 0,03722799 ! vasculogenesis GO:0001570 38 23 0,000 0,02627766 0,03720578 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,02627766 0,03718359 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,02627766 0,03716143 ! lysosome organization GO:0007040 41 23 0,000 0,02627766 0,0371393 ! digestive system process GO:0022600 35 23 0,000 0,02627766 0,03711719 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,02627766 0,03709511 ! vesicle targeting GO:0006903 35 23 0,000 0,02627766 0,03707306 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,02627766 0,03705103 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,02627766 0,03702903 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,02627766 0,03700705 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,02627766 0,0369851 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,02627766 0,03696318 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,02627766 0,03694128 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,02627766 0,03691941 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,02627766 0,03689756 ! membrane depolarization GO:0051899 40 23 0,000 0,02627766 0,03687574 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02627766 0,03685395 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,02627766 0,03683218 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,02627766 0,03681044 ! DNA modification GO:0006304 33 23 0,000 0,02627766 0,03678872 ! collagen fibril organization GO:0030199 50 23 0,000 0,02627766 0,03676703 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,02627766 0,03674536 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,02627766 0,03672372 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,02627766 0,03670211 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,02627766 0,03668052 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02627766 0,03665896 ! collagen catabolic process GO:0030574 29 23 0,000 0,02627766 0,03663742 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,02627766 0,0366159 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,02627766 0,03659442 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,02627766 0,03657295 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,02627766 0,03655151 ! blastocyst development GO:0001824 41 23 0,000 0,02627766 0,0365301 ! actin filament-based movement GO:0030048 37 23 0,000 0,02627766 0,03650871 ! protein stabilization GO:0050821 34 23 0,000 0,02627766 0,03648735 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,02740505 0,03803052 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,02740505 0,03800829 ! myelination GO:0042552 39 24 0,000 0,02740505 0,03798609 ! initiation of viral infection GO:0019059 47 24 0,000 0,02740505 0,03796391 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,02740505 0,03794176 ! leukocyte adhesion GO:0007159 49 24 0,000 0,02740505 0,03791964 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,02740505 0,03789754 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,02740505 0,03787547 ! visual behavior GO:0007632 42 24 0,000 0,02740505 0,03785342 ! spinal cord development GO:0021510 41 24 0,000 0,02740505 0,0378314 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,02740505 0,03780941 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,02740505 0,03778744 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,02740505 0,03776549 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,02740505 0,03774358 ! cell aging GO:0007569 38 24 0,000 0,02740505 0,03772168 ! osteoblast differentiation GO:0001649 43 24 0,000 0,02740505 0,03769982 ! response to toxin GO:0009636 38 24 0,000 0,02740505 0,03767797 ! primary neural tube formation GO:0014020 37 24 0,000 0,02740505 0,03765616 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,02740505 0,03763436 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,02740505 0,0376126 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,02740505 0,03759086 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,02740505 0,03756914 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,02740505 0,03754745 ! pentose metabolic process GO:0019321 33 24 0,000 0,02740505 0,03752578 ! immunoglobulin production GO:0002377 37 24 0,000 0,02740505 0,03750414 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,02740505 0,03748253 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,02740505 0,03746093 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,02740505 0,03743937 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,02740505 0,03741783 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,02740505 0,03739631 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,02740505 0,03737482 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,02740505 0,03735335 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,02740505 0,03733191 ! neuron fate commitment GO:0048663 38 25 0,000 0,02853119 0,03884367 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,02853119 0,0388214 ! superoxide metabolic process GO:0006801 33 25 0,000 0,02853119 0,03879915 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,02853119 0,03877693 GO:0050908|detection of light stimulus involved in visual perception, ! regulation of cell-matrix adhesion GO:0001952 57 25 0,000 0,02853119 0,03875473 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,02853119 0,03873256 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,02853119 0,03871042 ! vacuole organization GO:0007033 43 25 0,000 0,02853119 0,0386883 ! receptor metabolic process GO:0043112 40 25 0,000 0,02853119 0,0386662 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,02853119 0,03864413 GO:0051693|actin filament capping, ! regulation of behavior GO:0050795 45 25 0,000 0,02853119 0,03862209 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,02853119 0,03860007 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,02853119 0,03857807 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,02853119 0,0385561 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,02853119 0,03853416 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,02853119 0,03851224 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,02853119 0,03849034 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,02853119 0,03846848 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,02853119 0,03844663 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,02853119 0,03842481 ! regulation of amine transport GO:0051952 44 25 0,000 0,02853119 0,03840302 ! liver development GO:0001889 44 25 0,000 0,02853119 0,03838125 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,02965609 0,03987189 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,02965609 0,03984932 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,02965609 0,03982676 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,02965609 0,03980424 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,02965609 0,03978174 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,02965609 0,03975926 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,02965609 0,03973681 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,02965609 0,03971439 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,02965609 0,03969199 GO:0006479|protein amino acid methylation, ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,02965609 0,03966961 ! sperm motility GO:0030317 31 26 0,000 0,02965609 0,03964726 ! male gonad development GO:0008584 39 26 0,000 0,02965609 0,03962494 ! neural crest cell development GO:0014032 44 26 0,000 0,02965609 0,03960264 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,02965609 0,03958037 ! cell fate determination GO:0001709 54 26 0,000 0,02965609 0,03955812 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,02965609 0,03953589 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,02965609 0,0395137 ! detection of visible light GO:0009584 33 26 0,000 0,02965609 0,03949152 ! spermatid development GO:0007286 40 26 0,000 0,02965609 0,03946937 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,02965609 0,03944725 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,02965609 0,03942515 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,02965609 0,03940307 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,02965609 0,03938103 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03077973 0,04085029 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,03077973 0,04082745 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,03077973 0,04080464 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,03077973 0,04078186 ! membrane docking GO:0022406 40 27 0,000 0,03077973 0,0407591 ! circadian rhythm GO:0007623 44 27 0,000 0,03077973 0,04073637 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,03077973 0,04071366 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,03077973 0,04069098 ! autophagy GO:0006914 36 27 0,000 0,03077973 0,04066832 ! myofibril assembly GO:0030239 40 27 0,000 0,03077973 0,04064569 GO:0055002|striated muscle cell development, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,03077973 0,04062309 ! peptide transport GO:0015833 46 27 0,000 0,03077973 0,04060051 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,03077973 0,04057795 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,03077973 0,04055542 ! negative regulation of cell development GO:0010721 67 27 0,000 0,03077973 0,04053291 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,03077973 0,04051043 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,03077973 0,04048798 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,03077973 0,04046555 ! detection of light stimulus GO:0009583 35 27 0,000 0,03077973 0,04044314 ! glutathione metabolic process GO:0006749 35 27 0,000 0,03077973 0,04042076 ! lipid oxidation GO:0034440 39 27 0,000 0,03077973 0,0403984 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,03077973 0,04037607 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,03077973 0,04035376 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,03077973 0,04033148 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,03190214 0,04177913 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,03190214 0,04175608 ! translational initiation GO:0006413 48 28 0,000 0,03190214 0,04173306 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,03190214 0,04171007 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,03190214 0,0416871 ! regulation of pH GO:0006885 40 28 0,000 0,03190214 0,04166416 ! negative regulation of protein modification process GO:0031400 56 28 0,000 0,03190214 0,04164124 ! catechol metabolic process GO:0009712 46 28 0,000 0,03190214 0,04161835 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,03190214 0,04159548 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,03190214 0,04157264 ! iron ion homeostasis GO:0055072 49 28 0,000 0,03190214 0,04154982 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,03190214 0,04152703 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,03190214 0,04150426 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,03190214 0,04148152 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,03190214 0,0414588 ! gene silencing GO:0016458 47 28 0,000 0,03190214 0,04143611 ! regulation of coagulation GO:0050818 42 28 0,000 0,03190214 0,04141344 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,0330233 0,04284543 ! phenol metabolic process GO:0018958 47 29 0,000 0,0330233 0,04282202 ! positive regulation of cell adhesion GO:0045785 54 29 0,000 0,0330233 0,04279863 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,0330233 0,04277527 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,0330233 0,04275193 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,0330233 0,04272862 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,0330233 0,04270533 ! cholesterol transport GO:0030301 48 29 0,000 0,0330233 0,04268207 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,0330233 0,04265884 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,0330233 0,04263563 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,0330233 0,04261245 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,0330233 0,04258929 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,0330233 0,04256615 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,0330233 0,04254305 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,0330233 0,04251996 ! response to ionizing radiation GO:0010212 55 29 0,000 0,0330233 0,0424969 ! muscle cell development GO:0055001 42 29 0,000 0,0330233 0,04247387 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,0330233 0,04245086 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,0330233 0,04242788 ! mesoderm formation GO:0001707 52 29 0,000 0,0330233 0,04240492 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,0330233 0,04238198 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,0330233 0,04235908 ! ensheathment of neurons GO:0007272 48 29 0,000 0,0330233 0,04233619 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,0330233 0,04231333 ! spermatid differentiation GO:0048515 45 29 0,000 0,0330233 0,0422905 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,0330233 0,04226769 ! neural tube formation GO:0001841 46 29 0,000 0,0330233 0,0422449 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,03414322 0,04365402 ! organic anion transport GO:0015711 50 30 0,000 0,03414322 0,04363051 ! cell junction assembly GO:0034329 65 30 0,000 0,03414322 0,04360703 ! acute-phase response GO:0006953 49 30 0,000 0,03414322 0,04358357 ! segmentation GO:0035282 43 30 0,000 0,03414322 0,04356014 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,03414322 0,04353673 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,03414322 0,04351335 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,03414322 0,04348999 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,03414322 0,04346666 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,03414322 0,04344335 ! ceramide metabolic process GO:0006672 47 30 0,000 0,03414322 0,04342007 ! formation of primary germ layer GO:0001704 54 30 0,000 0,03414322 0,04339682 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,03414322 0,04337358 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,03414322 0,04335038 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,03414322 0,0433272 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,03414322 0,04330404 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,03414322 0,04328091 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,03414322 0,0432578 ! response to heat GO:0009408 43 30 0,000 0,03414322 0,04323472 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,03414322 0,04321166 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,0352619 0,04460367 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,0352619 0,0445799 ! post-embryonic development GO:0009791 50 31 0,000 0,0352619 0,04455617 ! regulation of innate immune response GO:0045088 42 31 0,000 0,0352619 0,04453245 ! ovulation cycle process GO:0022602 46 31 0,000 0,0352619 0,04450877 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,0352619 0,0444851 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,0352619 0,04446147 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,0352619 0,04443785 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,0352619 0,04441427 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,0352619 0,0443907 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,0352619 0,04436717 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,0352619 0,04434366 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,0352619 0,04432017 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,0352619 0,04429671 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,0352619 0,04427327 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,0352619 0,04424986 ! tissue homeostasis GO:0001894 45 31 0,000 0,0352619 0,04422647 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,03637933 0,04560389 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,03637933 0,04557981 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,03637933 0,04555576 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,03637933 0,04553173 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,03637933 0,04550773 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,03637933 0,04548375 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,03637933 0,0454598 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,03637933 0,04543587 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,03637933 0,04541197 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,03637933 0,0453881 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,03637933 0,04536425 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,03637933 0,04534042 ! telencephalon development GO:0021537 59 32 0,000 0,03637933 0,04531662 ! ovulation cycle GO:0042698 48 32 0,000 0,03637933 0,04529284 ! cofactor catabolic process GO:0051187 52 32 0,000 0,03637933 0,04526909 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,03637933 0,04524537 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,03637933 0,04522167 ! placenta development GO:0001890 45 32 0,000 0,03637933 0,04519799 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,03637933 0,04517434 ! vesicle localization GO:0051648 50 32 0,000 0,03637933 0,04515071 ! regulation of muscle development GO:0048634 52 33 0,000 0,03749553 0,04651171 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,03749553 0,04648741 ! negative regulation of secretion GO:0051048 53 33 0,000 0,03749553 0,04646314 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,03749553 0,04643889 ! glial cell differentiation GO:0010001 65 33 0,000 0,03749553 0,04641466 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,03749553 0,04639046 ! sister chromatid segregation GO:0000819 48 33 0,000 0,03749553 0,04636629 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,03749553 0,04634214 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,03749553 0,04631801 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,03749553 0,04629391 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,03749553 0,04626984 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,03749553 0,04624579 ! protein targeting to membrane GO:0006612 63 33 0,000 0,03749553 0,04622177 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,03749553 0,04619777 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,03749553 0,0461738 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,03749553 0,04614985 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,03749553 0,04612592 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,03749553 0,04610202 ! cytokine production GO:0001816 49 33 0,000 0,03749553 0,04607815 ! RNA modification GO:0009451 43 33 0,000 0,03749553 0,0460543 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,03749553 0,04603047 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,0386105 0,04737472 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,0386105 0,04735024 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,0386105 0,04732578 ! actomyosin structure organization GO:0031032 48 34 0,000 0,0386105 0,04730135 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,0386105 0,04727694 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,0386105 0,04725256 ! positive regulation of cell development GO:0010720 58 34 0,000 0,0386105 0,0472282 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,0386105 0,04720387 ! peripheral nervous system development GO:0007422 58 34 0,000 0,0386105 0,04717956 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,0386105 0,04715528 ! adult locomotory behavior GO:0008344 54 34 0,000 0,0386105 0,04713102 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,0386105 0,04710679 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,03972423 0,04844069 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,03972423 0,04841581 ! collagen metabolic process GO:0032963 47 35 0,000 0,03972423 0,04839096 ! cell junction organization GO:0034330 72 35 0,000 0,03972423 0,04836613 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,03972423 0,04834133 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,03972423 0,04831655 ! female gonad development GO:0008585 55 35 0,000 0,03972423 0,0482918 ! lipid homeostasis GO:0055088 63 35 0,000 0,03972423 0,04826707 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,03972423 0,04824237 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,03972423 0,04821769 ! hindbrain development GO:0030902 56 35 0,000 0,03972423 0,04819304 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,03972423 0,04816842 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,03972423 0,04814381 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,03972423 0,04811924 ! cytokinesis GO:0000910 57 35 0,000 0,03972423 0,04809469 ! embryonic organ development GO:0048568 53 35 0,000 0,03972423 0,04807016 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,03972423 0,04804566 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,03972423 0,04802119 ! protein homooligomerization GO:0051260 59 35 0,000 0,03972423 0,04799674 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,04083672 0,0493158 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,04083672 0,04929071 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,04083672 0,04926565 ! spliceosome assembly GO:0000245 65 36 0,000 0,04083672 0,04924062 ! mismatch repair GO:0006298 42 36 0,000 0,04083672 0,04921561 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,04083672 0,04919063 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,04083672 0,04916567 ! regulation of proteolysis GO:0030162 53 36 0,000 0,04083672 0,04914074 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,04083672 0,04911583 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,04083672 0,04909095 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,04083672 0,04906609 ! eye morphogenesis GO:0048592 64 36 0,000 0,04083672 0,04904126 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,04083672 0,04901646 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,04194798 0,05032485 ! mammary gland development GO:0030879 73 37 0,000 0,04194798 0,05029942 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,04194798 0,05027402 ! negative regulation of binding GO:0051100 59 37 0,000 0,04194798 0,05024864 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,04194798 0,05022329 ! tissue remodeling GO:0048771 65 37 0,000 0,04194798 0,05019796 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,04194798 0,05017266 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 58 37 0,000 0,04194798 0,05014739 ! natural killer cell activation GO:0030101 45 37 0,000 0,04194798 0,05012214 ! polyol metabolic process GO:0019751 47 37 0,000 0,04194798 0,05009691 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,04194798 0,05007171 ! glucan metabolic process GO:0044042 54 37 0,000 0,04194798 0,05004654 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,04305801 0,05134506 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,04305801 0,05131927 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,04305801 0,0512935 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,04305801 0,05126777 ! feeding behavior GO:0007631 50 38 0,000 0,04305801 0,05124206 ! organic ether metabolic process GO:0018904 51 38 0,000 0,04305801 0,05121637 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,04305801 0,05119071 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,04305801 0,05116508 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,04305801 0,05113947 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,04305801 0,05111389 ! ion transmembrane transport GO:0034220 58 38 0,000 0,04305801 0,05108833 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,04305801 0,0510628 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,04305801 0,05103729 ! neuron migration GO:0001764 59 38 0,000 0,04305801 0,05101181 ! maintenance of protein location GO:0045185 72 38 0,000 0,04305801 0,05098636 ! pigment metabolic process GO:0042440 66 38 0,000 0,04305801 0,05096093 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,04305801 0,05093552 ! mRNA catabolic process GO:0006402 58 39 0,000 0,04416681 0,05222115 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,04416681 0,05219514 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,04416681 0,05216916 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,04416681 0,0521432 ! neural tube development GO:0021915 58 39 0,000 0,04416681 0,05211728 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,04416681 0,05209137 ! regulation of protein stability GO:0031647 58 39 0,000 0,04416681 0,05206549 ! female gamete generation GO:0007292 50 39 0,000 0,04416681 0,05203964 ! aerobic respiration GO:0009060 56 39 0,000 0,04416681 0,05201382 ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,04416681 0,05198802 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,04527438 0,0532653 ! Notch signaling pathway GO:0007219 64 40 0,000 0,04527438 0,0532389 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,04527438 0,05321253 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,04527438 0,05318619 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,04527438 0,05315987 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,04527438 0,05313358 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,04527438 0,05310732 ! phagocytosis GO:0006909 65 40 0,000 0,04527438 0,05308108 ! mesenchymal cell development GO:0014031 70 40 0,000 0,04527438 0,05305487 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,04527438 0,05302868 ! B cell differentiation GO:0030183 70 40 0,000 0,04527438 0,05300252 ! pigmentation GO:0043473 81 40 0,000 0,04527438 0,05297638 ! developmental growth GO:0048589 70 40 0,000 0,04527438 0,05295027 ! synapse organization GO:0050808 61 40 0,000 0,04527438 0,05292419 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,04638072 0,05419077 ! RNA export from nucleus GO:0006405 57 41 0,000 0,04638072 0,0541641 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,04638072 0,05413746 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,04638072 0,05411084 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,04638072 0,05408425 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,04638072 0,05405769 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,04638072 0,05403115 ! cell growth GO:0016049 71 41 0,000 0,04638072 0,05400464 ! maintenance of location in cell GO:0051651 77 41 0,000 0,04638072 0,05397815 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,04748584 0,0552372 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,04748584 0,05521014 ! learning GO:0007612 75 42 0,000 0,04748584 0,0551831 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,04748584 0,05515609 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,04748584 0,05512911 ! gliogenesis GO:0042063 85 42 0,000 0,04748584 0,05510215 ! endosome transport GO:0016197 74 42 0,000 0,04748584 0,05507522 ! double-strand break repair GO:0006302 75 42 0,000 0,04748584 0,05504831 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,04748584 0,05502143 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,04748584 0,05499458 ! mitochondrial transport GO:0006839 66 43 0,000 0,04858973 0,05624558 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,04858973 0,05621815 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,04858973 0,05619076 ! regulation of tube size GO:0035150 69 43 0,000 0,04858973 0,05616339 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,04858973 0,05613604 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,04858973 0,05610873 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,04858973 0,05608144 ! T cell differentiation GO:0030217 78 43 0,000 0,04858973 0,05605417 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,04858973 0,05602693 ! amino acid activation GO:0043038 61 43 0,000 0,04858973 0,05599972 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,04858973 0,05597254 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,0496924 0,05721497 ! cellular component disassembly GO:0022411 66 44 0,000 0,0496924 0,05718723 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,0496924 0,05715951 ! peptide metabolic process GO:0006518 64 44 0,000 0,0496924 0,05713181 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,0496924 0,05710415 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,0496924 0,05707651 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,0496924 0,05704889 ! chromatin remodeling GO:0006338 73 44 0,000 0,0496924 0,05702131 ! biopolymer methylation GO:0043414 67 44 0,000 0,0496924 0,05699375 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,0496924 0,05696621 ! JNK cascade GO:0007254 66 44 0,000 0,0496924 0,05693871 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,0496924 0,05691123 ! regulation of cell shape GO:0008360 83 44 0,000 0,0496924 0,05688377 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,05079384 0,05811658 ! positive regulation of binding GO:0051099 67 45 0,000 0,05079384 0,05808857 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,05079384 0,05806059 ! regulation of ion transport GO:0043269 60 45 0,000 0,05079384 0,05803264 ! glucose transport GO:0015758 60 45 0,000 0,05079384 0,05800471 ! neuromuscular process GO:0050905 89 45 0,000 0,05079384 0,05797681 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,05079384 0,05794894 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,05079384 0,05792109 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,05079384 0,05789327 ! response to insulin stimulus GO:0032868 71 45 0,000 0,05079384 0,05786548 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,05189407 0,05909051 ! regulation of translational initiation GO:0006446 70 46 0,000 0,05189407 0,05906217 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,05189407 0,05903386 ! regulation of action potential GO:0001508 80 46 0,000 0,05189407 0,05900557 ! hexose transport GO:0008645 62 46 0,000 0,05189407 0,05897731 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,05189407 0,05894908 ! excretion GO:0007588 72 46 0,000 0,05189407 0,05892087 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,05189407 0,05889269 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,05189407 0,05886454 ! positive regulation of defense response GO:0031349 70 47 0,000 0,05299307 0,06008245 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,05299307 0,06005375 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,05299307 0,06002509 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,05299307 0,05999645 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,05409086 0,06121011 ! viral infectious cycle GO:0019058 80 48 0,000 0,05409086 0,06118094 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,05409086 0,06115179 ! leukocyte migration GO:0050900 76 48 0,000 0,05409086 0,06112267 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,05409086 0,06109358 ! striated muscle contraction GO:0006941 78 48 0,000 0,05409086 0,06106451 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,05409086 0,06103547 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,05409086 0,06100647 ! tRNA processing GO:0008033 56 48 0,000 0,05409086 0,06097748 ! cell maturation GO:0048469 69 48 0,000 0,05409086 0,06094853 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,05409086 0,0609196 ! vesicle organization GO:0016050 87 48 0,000 0,05409086 0,0608907 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,05409086 0,06086183 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,05518742 0,06206624 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,05518742 0,06203683 ! glycolysis GO:0006096 63 49 0,000 0,05518742 0,06200746 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,05518742 0,06197812 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,05518742 0,0619488 ! response to temperature stimulus GO:0009266 66 49 0,000 0,05518742 0,06191951 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,05518742 0,06189025 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,05518742 0,06186101 ! gastrulation GO:0007369 80 49 0,000 0,05518742 0,0618318 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,05518742 0,06180262 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,05518742 0,06177347 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,05518742 0,06174435 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,05518742 0,06171525 ! methylation GO:0032259 74 49 0,000 0,05518742 0,06168618 ! cell redox homeostasis GO:0045454 72 50 0,000 0,05628278 0,0628809 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,05628278 0,06285131 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,05628278 0,06282174 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,05628278 0,06279221 ! histone modification GO:0016570 81 50 0,000 0,05628278 0,0627627 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,05628278 0,06273322 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,05628278 0,06270377 ! RNA catabolic process GO:0006401 77 51 0,000 0,05737691 0,06389273 ! chloride transport GO:0006821 78 51 0,000 0,05737691 0,06386277 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,05737691 0,06383283 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,05737691 0,06380291 ! regulation of ossification GO:0030278 82 51 0,000 0,05737691 0,06377303 ! heart morphogenesis GO:0003007 71 51 0,000 0,05737691 0,06374317 ! RNA elongation GO:0006354 67 51 0,000 0,05737691 0,06371334 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,05737691 0,06368354 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,05846984 0,06486626 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,05846984 0,06483595 GO:0010863|positive regulation of phospholipase C activity, ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,05846984 0,06480566 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,05846984 0,06477541 ! covalent chromatin modification GO:0016569 90 52 0,000 0,05846984 0,06474518 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,05846984 0,06471498 ! proton transport GO:0015992 78 52 0,000 0,05846984 0,06468481 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,05846984 0,06465467 ! transition metal ion transport GO:0000041 88 53 0,000 0,05956155 0,06583119 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,05956155 0,06580054 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,05956155 0,06576992 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,05956155 0,06573933 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,05956155 0,06570877 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,05956155 0,06567823 ! regulation of endocytosis GO:0030100 71 53 0,000 0,05956155 0,06564773 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,05956155 0,06561725 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,05956155 0,0655868 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,05956155 0,06555638 ! maintenance of location GO:0051235 94 53 0,000 0,05956155 0,06552599 ! hydrogen transport GO:0006818 81 54 0,000 0,06065205 0,06669477 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,06065205 0,06666388 ! regulation of mitosis GO:0007088 91 54 0,000 0,06065205 0,06663302 GO:0051783|regulation of nuclear division, ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,06065205 0,06660218 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,06065205 0,06657138 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,06065205 0,0665406 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,06065205 0,06650985 ! germ cell development GO:0007281 82 54 0,000 0,06065205 0,06647913 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,06065205 0,06644844 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,06065205 0,06641777 ! establishment of organelle localization GO:0051656 91 54 0,000 0,06065205 0,06638714 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,06174134 0,06754827 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,06174134 0,06751714 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,06174134 0,06748605 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,06174134 0,06745497 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,06174134 0,06742393 ! regulation of actin filament length GO:0030832 88 56 0,000 0,06282942 0,0685806 ! positive regulation of secretion GO:0051047 83 56 0,000 0,06282942 0,06854907 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,06282942 0,06851757 ! DNA catabolic process GO:0006308 71 56 0,000 0,06282942 0,06848609 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,06282942 0,06845465 ! adult behavior GO:0030534 90 56 0,000 0,06282942 0,06842323 ! cartilage development GO:0051216 84 56 0,000 0,06282942 0,06839185 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,0639163 0,06954305 ! mesoderm development GO:0007498 84 57 0,000 0,0639163 0,06951117 ! aging GO:0007568 91 57 0,000 0,0639163 0,06947933 ! nuclear export GO:0051168 85 57 0,000 0,0639163 0,06944752 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,0639163 0,06941574 ! single fertilization GO:0007338 67 57 0,000 0,0639163 0,06938398 ! regulation of cellular component size GO:0032535 90 58 0,000 0,06500197 0,07053026 ! lipid modification GO:0030258 82 58 0,000 0,06500197 0,07049802 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,06500197 0,07046582 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,06500197 0,07043364 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,06608644 0,07157604 ! viral reproductive process GO:0022415 99 59 0,000 0,06608644 0,07154339 ! chromosome segregation GO:0007059 93 59 0,000 0,06608644 0,07151077 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,06608644 0,07147817 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,06608644 0,07144561 ! cell projection assembly GO:0030031 90 59 0,000 0,06608644 0,07141308 ! glucose catabolic process GO:0006007 78 60 0,000 0,0671697 0,07255061 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,0671697 0,0725176 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,0671697 0,07248463 ! response to peptide hormone stimulus GO:0043434 97 60 0,000 0,0671697 0,07245168 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,06825176 0,07358538 ! carbohydrate transport GO:0008643 83 61 0,000 0,06825176 0,07355196 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,06825176 0,07351858 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,06933262 0,07464896 ! amino acid transport GO:0006865 97 62 0,000 0,06933262 0,0746151 ! activation of MAPK activity GO:0000187 95 62 0,000 0,06933262 0,07458128 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,06933262 0,07454749 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,06933262 0,07451373 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,06933262 0,07447999 ! detection of external stimulus GO:0009581 78 62 0,000 0,06933262 0,07444629 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,06933262 0,07441262 ! secondary metabolic process GO:0019748 95 62 0,000 0,06933262 0,07437898 ! gonad development GO:0008406 91 62 0,000 0,06933262 0,07434537 ! exocytosis GO:0006887 91 63 0,000 0,07041228 0,07546899 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,07041228 0,07543492 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,07041228 0,07540088 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,07041228 0,07536687 ! regulation of heart contraction GO:0008016 104 63 0,000 0,07041228 0,07533289 ! developmental maturation GO:0021700 90 63 0,000 0,07041228 0,07529894 ! actin filament organization GO:0007015 107 64 0,000 0,07149074 0,07641781 ! fertilization GO:0009566 79 64 0,000 0,07149074 0,0763834 ! viral reproduction GO:0016032 104 64 0,000 0,07149074 0,07634902 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,07149074 0,07631468 ! amine catabolic process GO:0009310 100 65 0,000 0,07256801 0,0774298 ! camera-type eye development GO:0043010 103 65 0,000 0,07256801 0,077395 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,07256801 0,07736023 ! regulation of lipase activity GO:0060191 117 65 0,000 0,07256801 0,0773255 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,07256801 0,07729079 ! organelle localization GO:0051640 105 65 0,000 0,07256801 0,07725612 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,07364408 0,07836655 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,07364408 0,07833142 ! sensory perception of smell GO:0007608 81 66 0,000 0,07364408 0,07829632 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,07364408 0,07826126 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,07364408 0,07822623 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,07364408 0,07819123 ! B cell activation GO:0042113 119 66 0,000 0,07364408 0,07815626 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,07364408 0,07812132 ! protein oligomerization GO:0051259 109 66 0,000 0,07364408 0,07808642 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,07471895 0,07919074 ! neurotransmitter transport GO:0006836 92 67 0,000 0,07471895 0,07915539 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,07471895 0,07912007 ! appendage morphogenesis GO:0035107 103 67 0,000 0,07471895 0,07908478 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,07471895 0,07904952 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,07471895 0,07901429 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,07579264 0,080114 ! defense response to bacterium GO:0042742 79 68 0,000 0,07579264 0,08007833 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,07579264 0,08004269 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,07579264 0,08000708 ! activation of immune response GO:0002253 93 68 0,000 0,07579264 0,07997151 ! appendage development GO:0048736 108 69 0,000 0,07686513 0,08106709 GO:0060173|limb development, ! hexose catabolic process GO:0019320 95 70 0,000 0,07793643 0,08216044 ! adaptive immune response GO:0002250 102 70 0,000 0,07793643 0,08212395 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,07900654 0,08321461 ! cell-matrix adhesion GO:0007160 133 71 0,000 0,07900654 0,08317769 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,07900654 0,08314081 ! axon guidance GO:0007411 116 71 0,000 0,07900654 0,08310395 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,07900654 0,08306713 ! regulation of actin cytoskeleton organization GO:0032956 120 72 0,000 0,08007546 0,08415371 ! response to drug GO:0042493 115 72 0,000 0,08007546 0,08411645 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,08007546 0,08407923 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,08007546 0,08404205 ! rhythmic process GO:0048511 113 72 0,000 0,08007546 0,08400489 ! regulation of immune effector process GO:0002697 121 72 0,000 0,08007546 0,08396777 ! learning or memory GO:0007611 132 73 0,000 0,0811432 0,08504983 ! humoral immune response GO:0006959 93 73 0,000 0,0811432 0,08501228 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,0811432 0,08497476 ! acute inflammatory response GO:0002526 107 74 0,000 0,08220975 0,0860537 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,08220975 0,08601576 ! regulation of actin filament-based process GO:0032970 122 74 0,000 0,08220975 0,08597785 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,08220975 0,08593997 ! regulation of Rho protein signal transduction GO:0035023 126 74 0,000 0,08220975 0,08590213 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,08220975 0,08586432 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,08327512 0,08693878 ! inorganic anion transport GO:0015698 109 75 0,000 0,08327512 0,08690055 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,08327512 0,08686235 ! regulation of catabolic process GO:0009894 114 75 0,000 0,08327512 0,08682419 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,0843393 0,08789511 ! cell-substrate adhesion GO:0031589 141 76 0,000 0,0843393 0,08785652 ! regulation of Ras GTPase activity GO:0032318 125 76 0,000 0,0843393 0,08781797 ! negative regulation of transport GO:0051051 122 77 0,000 0,0854023 0,08888582 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,0854023 0,08884685 ! response to nutrient GO:0007584 114 77 0,000 0,0854023 0,08880791 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,0854023 0,08876902 ! regulation of blood pressure GO:0008217 119 78 0,000 0,08646412 0,08983335 ! muscle cell differentiation GO:0042692 117 78 0,000 0,08646412 0,08979403 ! amine transport GO:0015837 115 78 0,000 0,08646412 0,08975475 ! antigen processing and presentation GO:0019882 114 78 0,000 0,08646412 0,08971551 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,08752477 0,09077634 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,08858423 0,09183503 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,08858423 0,09179492 ! regulation of DNA binding GO:0051101 130 80 0,000 0,08858423 0,09175486 ! eye development GO:0001654 130 80 0,000 0,08858423 0,09171482 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,08858423 0,09167483 ! protein ubiquitination GO:0016567 135 80 0,000 0,08858423 0,09163486 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,08858423 0,09159494 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,08858423 0,09155504 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,08858423 0,09151518 ! blood coagulation GO:0007596 129 81 0,000 0,08964252 0,09256819 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,08964252 0,09252792 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,08964252 0,09248769 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,08964252 0,0924475 ! response to hypoxia GO:0001666 155 81 0,000 0,08964252 0,09240734 ! regulation of protein transport GO:0051223 123 81 0,000 0,08964252 0,09236721 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,09069963 0,09341589 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,09069963 0,09337537 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,09069963 0,09333487 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,09069963 0,09329442 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,09175557 0,09433967 ! response to oxygen levels GO:0070482 160 83 0,000 0,09175557 0,09429881 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,09175557 0,09425799 ! regulation of lyase activity GO:0051339 147 83 0,000 0,09175557 0,09421721 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,09175557 0,09417645 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,09281033 0,09521786 ! digestion GO:0007586 111 84 0,000 0,09281033 0,09517672 ! regulation of neurological system process GO:0031644 133 84 0,000 0,09281033 0,0951356 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,09281033 0,09509453 ! cellular respiration GO:0045333 119 85 0,000 0,09386393 0,09613254 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,09386393 0,09609107 ! T cell activation GO:0042110 154 85 0,000 0,09386393 0,09604963 ! protein import into nucleus GO:0006606 145 85 0,000 0,09386393 0,09600823 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,09386393 0,09596687 ! alcohol catabolic process GO:0046164 119 86 0,000 0,09491635 0,09700108 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,09491635 0,09695932 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,0959676 0,09799102 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,0959676 0,09794887 ! regulation of defense response GO:0031347 135 87 0,000 0,0959676 0,09790676 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,0959676 0,09786468 ! tRNA metabolic process GO:0006399 110 87 0,000 0,0959676 0,09782265 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,0959676 0,09778064 ! vitamin metabolic process GO:0006766 117 87 0,000 0,0959676 0,09773868 ! forebrain development GO:0030900 151 87 0,000 0,0959676 0,09769675 ! regulation of membrane potential GO:0042391 144 88 0,000 0,09701769 0,0987234 ! ossification GO:0001503 150 89 0,000 0,09806661 0,09974799 GO:0060348|bone development, ! nucleosome assembly GO:0006334 113 89 0,000 0,09806661 0,09970525 GO:0031497|chromatin assembly, ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,09911436 0,10072736 ! transcription initiation GO:0006352 128 90 0,000 0,09911436 0,10068424 ! regulation of GTPase activity GO:0043087 149 90 0,000 0,09911436 0,10064115 ! nuclear import GO:0051170 153 90 0,000 0,09911436 0,10059811 ! regulation of protein localization GO:0032880 141 90 0,000 0,09911436 0,1005551 ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,10016095 0,10157348 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,10016095 0,10153009 ! protein localization in nucleus GO:0034504 161 92 0,000 0,10120638 0,102546 ! sterol metabolic process GO:0016125 136 92 0,000 0,10120638 0,10250223 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,10225064 0,10351569 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,10225064 0,10347154 ! rRNA processing GO:0006364 124 93 0,000 0,10225064 0,10342744 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,10225064 0,10338337 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,10225064 0,10333934 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,10225064 0,10329535 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,10225064 0,10325139 ! leukocyte differentiation GO:0002521 165 94 0,000 0,10329374 0,10426034 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,10329374 0,10421601 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,10329374 0,10417172 ! rRNA metabolic process GO:0016072 125 94 0,000 0,10329374 0,10412747 ! regulation of cell adhesion GO:0030155 187 94 0,000 0,10329374 0,10408325 ! hormone metabolic process GO:0042445 135 94 0,000 0,10329374 0,10403907 ! protein processing GO:0016485 127 94 0,000 0,10329374 0,10399493 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,10433569 0,1049994 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,10433569 0,10495489 ! ATP metabolic process GO:0046034 150 96 0,000 0,10537647 0,10595694 ! nucleosome organization GO:0034728 126 96 0,000 0,10537647 0,10591206 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,10537647 0,10586722 ! female pregnancy GO:0007565 148 96 0,000 0,10537647 0,10582242 ! response to virus GO:0009615 141 98 0,000 0,10745458 0,10786367 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,10745458 0,10781806 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,10745458 0,10777249 ! regulation of T cell activation GO:0050863 155 98 0,000 0,10745458 0,10772696 ! regulation of binding GO:0051098 164 99 0,000 0,1084919 0,10872097 ! electron transport chain GO:0022900 135 99 0,000 0,1084919 0,10867508 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,1084919 0,10862923 ! positive regulation of immune response GO:0050778 143 99 0,000 0,1084919 0,10858341 ! sulfur metabolic process GO:0006790 136 99 0,000 0,1084919 0,10853763 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,10952806 0,10952806