pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/9643-11-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 2,327E-09 5,599E-06 ! thymus development GO:0048538 27 11 2,000 1,318E-07 1,585E-04 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 1,603E-06 1,285E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 2,312E-06 1,39E-03 ! muscle cell migration GO:0014812 8 5 1,000 8,937E-06 4,3E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 1,108E-05 4,445E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,185E-05 4,073E-03 ! response to UV GO:0009411 104 53 2,000 1,82E-05 5,475E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,498E-05 6,677E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 3,209E-05 7,722E-03 ! induction of an organ GO:0001759 14 9 1,000 3,209E-05 7,02E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 3,689E-05 7,397E-03 ! negative regulation of kinase activity GO:0033673 131 68 2,000 3,857E-05 7,138E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,009E-05 6,89E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,009E-05 6,431E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 4,578E-05 6,884E-03 ! thyroid gland development GO:0030878 26 11 1,000 4,897E-05 6,931E-03 ! developmental induction GO:0031128 19 11 1,000 4,897E-05 6,546E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of B cell proliferation GO:0030888 20 12 1,000 5,873E-05 7,438E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 5,873E-05 7,066E-03 ! T cell homeostasis GO:0043029 25 12 1,000 5,873E-05 6,729E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 8,089E-05 8,846E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 8,089E-05 8,461E-03 GO:0060675|ureteric bud morphogenesis, ! male genitalia development GO:0030539 24 14 1,000 8,089E-05 8,109E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 8,089E-05 7,784E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 9,327E-05 8,631E-03 ! lymphocyte homeostasis GO:0002260 30 15 1,000 9,327E-05 8,312E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,047E-04 8,995E-03 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,065E-04 8,839E-03 GO:0031114|regulation of microtubule depolymerization, ! interphase GO:0051325 213 98 2,000 1,148E-04 9,207E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 1,207E-04 9,365E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 1,207E-04 9,073E-03 ! genitalia development GO:0048806 30 17 1,000 1,207E-04 8,798E-03 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,207E-04 8,539E-03 ! skin development GO:0043588 36 19 1,000 1,515E-04 0,01041737 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,515E-04 0,010128 GO:0030968|endoplasmic reticulum unfolded protein response, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,683E-04 0,01094265 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 1,859E-04 0,0117692 ! ureteric bud development GO:0001657 43 22 1,000 2,043E-04 0,01260664 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,043E-04 0,01229147 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,043E-04 0,01199168 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,237E-04 0,01281338 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,439E-04 0,01364501 ! leukocyte homeostasis GO:0001776 44 24 1,000 2,439E-04 0,01333489 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,649E-04 0,01416389 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,649E-04 0,01385598 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,649E-04 0,01356117 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 2,868E-04 0,01437661 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,868E-04 0,01408321 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,868E-04 0,01380155 GO:0045936|negative regulation of phosphate metabolic process, ! fat cell differentiation GO:0045444 50 27 1,000 3,096E-04 0,01460468 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,332E-04 0,01541644 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,332E-04 0,01512557 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 3,577E-04 0,01593561 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 3,577E-04 0,01564587 ! regulation of B cell activation GO:0050864 50 30 1,000 3,83E-04 0,01645426 ! inner ear morphogenesis GO:0042472 47 31 1,000 4,091E-04 0,01727014 ! spindle organization GO:0007051 46 32 1,000 4,362E-04 0,01809307 ! metanephros development GO:0001656 74 32 1,000 4,362E-04 0,01778641 ! cell fate specification GO:0001708 52 33 1,000 4,64E-04 0,01860724 ! odontogenesis GO:0042476 66 35 1,000 5,223E-04 0,02060003 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 5,223E-04 0,02026777 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 5,223E-04 0,01994606 ! regulation of microtubule-based process GO:0032886 78 35 1,000 5,223E-04 0,01963441 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 5,527E-04 0,02045732 ! meiosis I GO:0007127 65 37 1,000 5,839E-04 0,02128593 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 6,16E-04 0,02211992 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 6,16E-04 0,02179463 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! ear morphogenesis GO:0042471 60 39 1,000 6,489E-04 0,02262627 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 6,489E-04 0,02230304 ! keratinocyte differentiation GO:0030216 62 41 1,000 7,172E-04 0,02430419 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 7,526E-04 0,02514995 ! epithelial cell differentiation GO:0030855 79 43 1,000 7,889E-04 0,02599993 ! male sex differentiation GO:0046661 76 44 1,000 8,259E-04 0,02685391 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 8,638E-04 0,02771169 ! epidermal cell differentiation GO:0009913 68 46 1,000 9,026E-04 0,02857306 ! response to calcium ion GO:0051592 81 47 1,000 9,421E-04 0,02943783 ! positive regulation of cell cycle GO:0045787 89 48 1,000 9,825E-04 0,03030584 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 9,825E-04 0,02992222 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 1,024E-03 0,03078719 ! endocrine system development GO:0035270 104 49 1,000 1,024E-03 0,0304071 ! inner ear development GO:0048839 79 50 1,000 1,066E-03 0,03126914 ! embryonic skeletal system development GO:0048706 85 51 1,000 1,109E-03 0,03213415 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 1,109E-03 0,0317516 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 1,000 1,109E-03 0,03137805 ! positive regulation of growth GO:0045927 90 52 1,000 1,152E-03 0,03223448 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 1,152E-03 0,03186397 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 1,242E-03 0,03395585 ! skeletal muscle fiber development GO:0048741 111 56 1,000 1,335E-03 0,03608863 ! regulation of DNA replication GO:0006275 101 56 1,000 1,335E-03 0,03568765 ! muscle fiber development GO:0048747 112 57 1,000 1,383E-03 0,03655714 ! positive regulation of cell migration GO:0030335 126 57 1,000 1,383E-03 0,03615978 ! skeletal system morphogenesis GO:0048705 105 59 1,000 1,481E-03 0,03830275 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 1,531E-03 0,03917864 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 1,531E-03 0,03876623 ! kidney development GO:0001822 122 60 1,000 1,531E-03 0,03836242 ! ear development GO:0043583 103 62 1,000 1,633E-03 0,04051408 ! positive regulation of cell motion GO:0051272 146 64 1,000 1,739E-03 0,04270049 ! extracellular matrix organization GO:0030198 133 66 1,000 1,848E-03 0,04492032 ! negative regulation of cell growth GO:0030308 132 67 1,000 1,904E-03 0,04581215 ! lung development GO:0030324 144 67 1,000 1,904E-03 0,04535856 ! homeostasis of number of cells GO:0048872 114 67 1,000 1,904E-03 0,04491387 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 1,961E-03 0,04579833 ! negative regulation of cell size GO:0045792 134 69 1,000 2,018E-03 0,0466841 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 2,018E-03 0,04623949 ! urogenital system development GO:0001655 137 69 1,000 2,018E-03 0,04580327 ! respiratory tube development GO:0030323 150 70 1,000 2,076E-03 0,04668194 ! regulation of caspase activity GO:0043281 122 72 1,000 2,195E-03 0,0488917 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 2,195E-03 0,04844315 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 2,195E-03 0,04800276 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 2,195E-03 0,0475703 ! respiratory system development GO:0060541 153 72 1,000 2,195E-03 0,04714557 ! meiosis GO:0007126 121 74 1,000 2,316E-03 0,04932041 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 2,316E-03 0,04888778 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 2,378E-03 0,04976076 ! meiotic cell cycle GO:0051321 122 75 1,000 2,378E-03 0,04933179 ! development of primary sexual characteristics GO:0045137 124 76 1,000 2,441E-03 0,05020213 ! positive regulation of ligase activity GO:0051351 124 77 1,000 2,505E-03 0,05107363 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 2,505E-03 0,05064444 ! negative regulation of organelle organization GO:0010639 161 78 1,000 2,569E-03 0,05151336 ! regulation of peptidase activity GO:0052547 134 79 1,000 2,634E-03 0,05238337 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 2,634E-03 0,051954 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 2,634E-03 0,05153161 ! response to metal ion GO:0010038 140 80 1,000 2,7E-03 0,05239548 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 2,767E-03 0,05326045 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of neuron differentiation GO:0045664 167 81 1,000 2,767E-03 0,05283775 ! negative regulation of growth GO:0045926 155 84 1,000 2,972E-03 0,0563012 ! regulation of ligase activity GO:0051340 142 84 1,000 2,972E-03 0,05586135 ! response to unfolded protein GO:0006986 131 85 1,000 3,042E-03 0,05673015 ! positive regulation of cell activation GO:0050867 145 85 1,000 3,042E-03 0,05629376 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 3,112E-03 0,05716009 ! tube morphogenesis GO:0035239 176 86 1,000 3,112E-03 0,05672706 ! mitochondrion organization GO:0007005 148 86 1,000 3,112E-03 0,05630054 ! positive regulation of protein modification process GO:0031401 136 88 1,000 3,256E-03 0,0584557 ! gland development GO:0048732 206 88 1,000 3,256E-03 0,05802269 ! sex differentiation GO:0007548 145 90 1,000 3,402E-03 0,0601875 ! response to protein stimulus GO:0051789 149 91 1,000 3,477E-03 0,06105448 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 3,628E-03 0,0632454 GO:0010498|proteasomal protein catabolic process, ! regulation of DNA metabolic process GO:0051052 178 97 1,000 3,939E-03 0,06817602 ! skeletal muscle tissue development GO:0007519 186 99 1,000 4,099E-03 0,07044009 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 4,18E-03 0,07132542 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 4,806E-03 0,08142467 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 4,806E-03 0,08085526 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,806E-03 0,08029377 ! positive regulation of helicase activity GO:0051096 11 5 0,000 4,806E-03 0,07974002 ! neuron fate determination GO:0048664 7 5 0,000 4,806E-03 0,07919385 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,806E-03 0,07865512 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 4,806E-03 0,07812367 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 4,806E-03 0,07759935 ! polyol transport GO:0015791 12 5 0,000 4,806E-03 0,07708202 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 4,806E-03 0,07657154 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,806E-03 0,07606778 ! response to superoxide GO:0000303 10 5 0,000 4,806E-03 0,0755706 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,806E-03 0,07507989 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 4,806E-03 0,0745955 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 4,806E-03 0,07411732 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,806E-03 0,07364524 ! female meiosis GO:0007143 7 5 0,000 4,806E-03 0,07317913 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 4,806E-03 0,07271888 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,806E-03 0,07226439 ! cobalt ion transport GO:0006824 11 5 0,000 4,806E-03 0,07181554 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 4,806E-03 0,07137224 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 4,806E-03 0,07093437 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 4,806E-03 0,07050184 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,806E-03 0,07007456 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,806E-03 0,06965242 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 4,806E-03 0,06923534 ! embryonic camera-type eye development GO:0031076 10 5 0,000 4,806E-03 0,06882323 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,806E-03 0,06841599 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 4,806E-03 0,06801354 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 4,806E-03 0,0676158 ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,806E-03 0,06722269 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,806E-03 0,06683412 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,806E-03 0,06645001 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 4,806E-03 0,0660703 ! negative chemotaxis GO:0050919 14 5 0,000 4,806E-03 0,0656949 ! positive regulation of histone modification GO:0031058 5 5 0,000 4,806E-03 0,06532374 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,806E-03 0,06495676 ! sensory perception of bitter taste GO:0050913 7 5 0,000 4,806E-03 0,06459387 ! behavioral response to pain GO:0048266 9 5 0,000 4,806E-03 0,06423501 ! clathrin coat assembly GO:0048268 14 5 0,000 4,806E-03 0,06388012 ! Notch receptor processing GO:0007220 8 5 0,000 4,806E-03 0,06352913 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,806E-03 0,06318198 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 4,806E-03 0,0628386 ! micturition GO:0060073 9 5 0,000 4,806E-03 0,06249893 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,806E-03 0,06216292 ! copulation GO:0007620 9 5 0,000 4,806E-03 0,06183049 ! glial cell fate commitment GO:0021781 13 5 0,000 4,806E-03 0,06150161 ! protein maturation by protein folding GO:0022417 13 5 0,000 4,806E-03 0,0611762 ! spermidine metabolic process GO:0008216 7 5 0,000 4,806E-03 0,06085422 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,806E-03 0,06053562 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,806E-03 0,06022033 ! apoptotic cell clearance GO:0043277 20 5 0,000 4,806E-03 0,0599083 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,806E-03 0,0595995 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,806E-03 0,05929386 ! grooming behavior GO:0007625 6 5 0,000 4,806E-03 0,05899134 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,806E-03 0,05869189 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 4,806E-03 0,05839547 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,806E-03 0,05810202 ! response to protozoan GO:0001562 10 5 0,000 4,806E-03 0,05781151 ! positive regulation of glycolysis GO:0045821 14 5 0,000 4,806E-03 0,05752389 ! lymph vessel development GO:0001945 10 5 0,000 4,806E-03 0,05723912 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 4,806E-03 0,05695716 ! endochondral ossification GO:0001958 16 5 0,000 4,806E-03 0,05667795 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,806E-03 0,05640148 ! parathyroid gland development GO:0060017 13 5 0,000 4,806E-03 0,05612768 ! anagen GO:0042640 6 5 0,000 4,806E-03 0,05585653 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,806E-03 0,05558799 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,806E-03 0,05532202 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 4,806E-03 0,05505858 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 4,806E-03 0,05479764 ! dorsal spinal cord development GO:0021516 7 5 0,000 4,806E-03 0,05453916 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 4,806E-03 0,05428311 ! sphingoid catabolic process GO:0046521 6 5 0,000 4,806E-03 0,05402945 ! skeletal myofibril assembly GO:0014866 10 5 0,000 4,806E-03 0,05377815 ! smooth muscle tissue development GO:0048745 28 5 0,000 4,806E-03 0,05352918 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,806E-03 0,0532825 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,806E-03 0,05303809 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,806E-03 0,0527959 ! cardiac muscle fiber development GO:0048739 10 5 0,000 4,806E-03 0,05255592 ! transepithelial chloride transport GO:0030321 9 5 0,000 4,806E-03 0,05231811 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,806E-03 0,05208244 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 4,806E-03 0,05184889 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 4,806E-03 0,05161742 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,806E-03 0,05138801 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,806E-03 0,05116063 ! histidine catabolic process GO:0006548 6 5 0,000 4,806E-03 0,05093525 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 4,806E-03 0,05071185 ! microvillus organization GO:0032528 7 5 0,000 4,806E-03 0,0504904 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 4,806E-03 0,05027088 ! L-serine biosynthetic process GO:0006564 6 5 0,000 4,806E-03 0,05005326 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,806E-03 0,04983751 ! tryptophan metabolic process GO:0006568 9 5 0,000 4,806E-03 0,04962362 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 4,806E-03 0,04941155 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 4,806E-03 0,04920129 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 4,806E-03 0,04899281 ! polyol catabolic process GO:0046174 7 5 0,000 4,806E-03 0,04878609 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 4,806E-03 0,0485811 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 4,806E-03 0,04837783 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,806E-03 0,04817626 ! mitochondrial fission GO:0000266 8 5 0,000 4,806E-03 0,04797636 ! sister chromatid cohesion GO:0007062 12 5 0,000 4,806E-03 0,04777811 ! mRNA transcription GO:0009299 9 5 0,000 4,806E-03 0,04758149 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 4,806E-03 0,04738649 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 4,806E-03 0,04719307 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 4,806E-03 0,04700123 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 4,806E-03 0,04681094 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,806E-03 0,04662219 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,806E-03 0,04643495 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,806E-03 0,04624921 ! response to food GO:0032094 6 5 0,000 4,806E-03 0,04606495 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,806E-03 0,04588215 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,806E-03 0,0457008 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 4,806E-03 0,04552088 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,806E-03 0,04534236 ! paraxial mesoderm development GO:0048339 14 5 0,000 4,806E-03 0,04516524 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 4,806E-03 0,0449895 ! forebrain neuron development GO:0021884 13 5 0,000 4,806E-03 0,04481513 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,806E-03 0,04464209 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 4,806E-03 0,04447039 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,806E-03 0,04430001 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,806E-03 0,04413093 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,806E-03 0,04396313 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 4,806E-03 0,0437966 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,806E-03 0,04363133 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 4,806E-03 0,0434673 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 4,806E-03 0,0433045 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,806E-03 0,04314292 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 4,806E-03 0,04298254 ! basic amino acid transport GO:0015802 11 5 0,000 4,806E-03 0,04282334 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,806E-03 0,04266532 ! early endosome to late endosome transport GO:0045022 12 5 0,000 4,806E-03 0,04250847 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,806E-03 0,04235276 ! depyrimidination GO:0045008 10 5 0,000 4,806E-03 0,04219818 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,806E-03 0,04204474 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,806E-03 0,0418924 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,806E-03 0,04174116 ! zinc ion homeostasis GO:0055069 8 5 0,000 4,806E-03 0,04159102 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 4,806E-03 0,04144194 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 4,806E-03 0,04129394 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,806E-03 0,04114698 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,806E-03 0,04100107 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,806E-03 0,04085619 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 4,806E-03 0,04071233 ! peptidyl-arginine modification GO:0018195 9 5 0,000 4,806E-03 0,04056948 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,806E-03 0,04042763 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,806E-03 0,04028677 ! response to arsenic GO:0046685 10 5 0,000 4,806E-03 0,04014688 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 4,806E-03 0,04000797 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,806E-03 0,03987001 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 4,806E-03 0,039733 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 4,806E-03 0,03959693 ! response to cadmium ion GO:0046686 7 5 0,000 4,806E-03 0,03946178 ! bile acid biosynthetic process GO:0006699 6 5 0,000 4,806E-03 0,03932756 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 4,806E-03 0,03919425 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,806E-03 0,03906183 ! decidualization GO:0046697 11 5 0,000 4,806E-03 0,03893031 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 4,806E-03 0,03879967 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 4,806E-03 0,03866991 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 4,806E-03 0,03854101 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 4,806E-03 0,03841297 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 4,806E-03 0,03828577 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,806E-03 0,03815941 ! neural tube patterning GO:0021532 7 5 0,000 4,806E-03 0,03803389 ! embryonic cleavage GO:0040016 6 5 0,000 4,806E-03 0,03790919 ! peroxisome fission GO:0016559 5 5 0,000 4,806E-03 0,0377853 ! histone demethylation GO:0016577 10 5 0,000 4,806E-03 0,03766222 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 4,806E-03 0,03753994 ! mitotic recombination GO:0006312 9 5 0,000 4,806E-03 0,03741845 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,806E-03 0,03729775 ! metaphase plate congression GO:0051310 7 5 0,000 4,806E-03 0,03717782 ! regulation of sterol transport GO:0032371 7 5 0,000 4,806E-03 0,03705866 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,806E-03 0,03694026 ! enteric nervous system development GO:0048484 8 5 0,000 4,806E-03 0,03682262 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 4,806E-03 0,03670572 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 4,806E-03 0,03658957 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 4,806E-03 0,03647414 ! muscle cell proliferation GO:0033002 11 5 0,000 4,806E-03 0,03635944 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,806E-03 0,03624546 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 4,806E-03 0,0361322 ! plasminogen activation GO:0031639 5 5 0,000 4,806E-03 0,03601963 ! B cell homeostasis GO:0001782 13 5 0,000 4,806E-03 0,03590777 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 4,806E-03 0,0357966 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,806E-03 0,03568612 ! metaphase GO:0051323 8 5 0,000 4,806E-03 0,03557632 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 4,806E-03 0,03546719 ! cellular response to nutrient GO:0031670 8 5 0,000 4,806E-03 0,03535872 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,806E-03 0,03525092 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 4,806E-03 0,03514378 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 4,806E-03 0,03503728 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 4,806E-03 0,03493143 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 4,806E-03 0,03482621 ! response to redox state GO:0051775 5 5 0,000 4,806E-03 0,03472163 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 4,806E-03 0,03461767 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 4,806E-03 0,03451434 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,806E-03 0,03441161 ! regulation of telomerase activity GO:0051972 6 5 0,000 4,806E-03 0,0343095 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,806E-03 0,034208 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 4,806E-03 0,03410709 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,806E-03 0,03400677 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 4,806E-03 0,03390705 ! striatum development GO:0021756 9 5 0,000 4,806E-03 0,0338079 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 4,806E-03 0,03370934 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 4,806E-03 0,03361134 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,806E-03 0,03351392 ! glial cell migration GO:0008347 11 5 0,000 4,806E-03 0,03341706 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,806E-03 0,03332076 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 4,806E-03 0,03322501 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 4,806E-03 0,03312981 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,806E-03 0,03303515 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,806E-03 0,03294103 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,806E-03 0,03284745 ! neuroprotection GO:0043526 6 5 0,000 4,806E-03 0,0327544 ! neural plate development GO:0001840 8 5 0,000 4,806E-03 0,03266187 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,806E-03 0,03256987 ! regulation of sensory perception GO:0051931 7 5 0,000 4,806E-03 0,03247838 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,806E-03 0,0323874 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,806E-03 0,03229693 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 4,806E-03 0,03220697 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 4,806E-03 0,03211751 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,806E-03 0,03202854 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,806E-03 0,03194006 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,806E-03 0,03185207 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,806E-03 0,03176457 ! spindle assembly GO:0051225 6 5 0,000 4,806E-03 0,03167754 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,806E-03 0,03159099 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,806E-03 0,03150491 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,806E-03 0,0314193 ! drug metabolic process GO:0017144 6 5 0,000 4,806E-03 0,03133415 ! stem cell division GO:0017145 11 5 0,000 4,806E-03 0,03124947 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,806E-03 0,03116524 ! organ regeneration GO:0031100 7 5 0,000 4,806E-03 0,03108146 ! carnitine metabolic process GO:0009437 7 5 0,000 4,806E-03 0,03099813 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 4,806E-03 0,03091525 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,806E-03 0,03083281 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 5,764E-03 0,03688382 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,764E-03 0,03678599 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 5,764E-03 0,03668867 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 5,764E-03 0,03659186 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 5,764E-03 0,03649557 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 5,764E-03 0,03639978 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 5,764E-03 0,03630449 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 5,764E-03 0,0362097 ! sleep GO:0030431 13 6 0,000 5,764E-03 0,03611541 ! response to oxygen radical GO:0000305 11 6 0,000 5,764E-03 0,0360216 ! positive regulation of axon extension GO:0045773 11 6 0,000 5,764E-03 0,03592828 ! myoblast cell fate commitment GO:0048625 16 6 0,000 5,764E-03 0,03583544 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 5,764E-03 0,03574308 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 5,764E-03 0,0356512 ! regulation of interferon-beta production GO:0032648 8 6 0,000 5,764E-03 0,03555979 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 5,764E-03 0,03546884 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 5,764E-03 0,03537836 ! forebrain regionalization GO:0021871 8 6 0,000 5,764E-03 0,03528834 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 5,764E-03 0,03519877 ! male meiosis GO:0007140 7 6 0,000 5,764E-03 0,03510966 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 5,764E-03 0,035021 ! response to zinc ion GO:0010043 9 6 0,000 5,764E-03 0,03493279 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 5,764E-03 0,03484502 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 5,764E-03 0,03475769 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 5,764E-03 0,03467079 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 5,764E-03 0,03458433 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 5,764E-03 0,0344983 ! malate metabolic process GO:0006108 11 6 0,000 5,764E-03 0,0344127 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 5,764E-03 0,03432752 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 5,764E-03 0,03424276 ! protein refolding GO:0042026 15 6 0,000 5,764E-03 0,03415842 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 5,764E-03 0,03407449 ! opsonization GO:0008228 8 6 0,000 5,764E-03 0,03399097 ! mating behavior GO:0007617 7 6 0,000 5,764E-03 0,03390786 ! neuron remodeling GO:0016322 15 6 0,000 5,764E-03 0,03382516 ! erythrocyte maturation GO:0043249 7 6 0,000 5,764E-03 0,03374286 ! embryonic hemopoiesis GO:0035162 14 6 0,000 5,764E-03 0,03366096 ! equilibrioception GO:0050957 14 6 0,000 5,764E-03 0,03357946 ! protein amino acid dealkylation GO:0008214 12 6 0,000 5,764E-03 0,03349835 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 5,764E-03 0,03341763 ! photoreceptor cell development GO:0042461 10 6 0,000 5,764E-03 0,0333373 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 5,764E-03 0,03325735 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 5,764E-03 0,03317779 ! response to interferon-gamma GO:0034341 15 6 0,000 5,764E-03 0,03309861 ! toxin metabolic process GO:0009404 11 6 0,000 5,764E-03 0,0330198 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 5,764E-03 0,03294137 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 5,764E-03 0,03286331 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 5,764E-03 0,03278562 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 5,764E-03 0,03270829 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 5,764E-03 0,03263133 ! cGMP-mediated signaling GO:0019934 13 6 0,000 5,764E-03 0,03255473 ! activation of MAPKKK activity GO:0000185 12 6 0,000 5,764E-03 0,03247849 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 5,764E-03 0,03240261 ! thymic T cell selection GO:0045061 12 6 0,000 5,764E-03 0,03232708 ! protein lipoylation GO:0009249 10 6 0,000 5,764E-03 0,0322519 ! cysteine metabolic process GO:0006534 10 6 0,000 5,764E-03 0,03217707 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 5,764E-03 0,03210258 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 5,764E-03 0,03202844 ! glutamate catabolic process GO:0006538 10 6 0,000 5,764E-03 0,03195465 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 5,764E-03 0,03188119 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 5,764E-03 0,03180807 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 5,764E-03 0,03173528 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 5,764E-03 0,03166282 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 5,764E-03 0,0315907 ! hyperosmotic response GO:0006972 9 6 0,000 5,764E-03 0,0315189 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 5,764E-03 0,03144743 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 5,764E-03 0,03137628 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 5,764E-03 0,03130545 ! urea metabolic process GO:0019627 7 6 0,000 5,764E-03 0,03123495 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 5,764E-03 0,03116476 ! neutrophil activation GO:0042119 8 6 0,000 5,764E-03 0,03109488 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 5,764E-03 0,03102532 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 5,764E-03 0,03095606 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 5,764E-03 0,03088712 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 5,764E-03 0,03081848 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 5,764E-03 0,03075015 ! neuron apoptosis GO:0051402 9 6 0,000 5,764E-03 0,03068212 ! nucleoside salvage GO:0043174 9 6 0,000 5,764E-03 0,03061439 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 5,764E-03 0,03054695 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 5,764E-03 0,03047982 ! T cell mediated immunity GO:0002456 16 6 0,000 5,764E-03 0,03041297 ! negative regulation of platelet activation GO:0010544 9 6 0,000 5,764E-03 0,03034643 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 5,764E-03 0,03028017 ! carnitine transport GO:0015879 10 6 0,000 5,764E-03 0,0302142 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 5,764E-03 0,03014851 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,764E-03 0,03008312 ! positive regulation of exocytosis GO:0045921 8 6 0,000 5,764E-03 0,030018 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 5,764E-03 0,02995317 ! 5S class rRNA transcription GO:0042791 11 6 0,000 5,764E-03 0,02988861 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 5,764E-03 0,02982434 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 5,764E-03 0,02976034 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 5,764E-03 0,02969661 ! sodium ion homeostasis GO:0055078 11 6 0,000 5,764E-03 0,02963315 ! establishment of spindle localization GO:0051293 12 6 0,000 5,764E-03 0,02956997 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 5,764E-03 0,02950706 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 5,764E-03 0,02944441 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 5,764E-03 0,02938203 ! neural nucleus development GO:0048857 14 6 0,000 5,764E-03 0,02931991 ! response to UV-C GO:0010225 11 6 0,000 5,764E-03 0,02925805 ! astrocyte development GO:0014002 15 6 0,000 5,764E-03 0,02919646 ! protein targeting to lysosome GO:0006622 10 6 0,000 5,764E-03 0,02913512 ! purine base biosynthetic process GO:0009113 17 6 0,000 5,764E-03 0,02907404 ! interaction with symbiont GO:0051702 13 6 0,000 5,764E-03 0,02901321 ! regulation of dendrite development GO:0050773 16 6 0,000 5,764E-03 0,02895264 ! skeletal muscle contraction GO:0003009 6 6 0,000 5,764E-03 0,02889233 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 5,764E-03 0,02883226 ! response to copper ion GO:0046688 10 6 0,000 5,764E-03 0,02877244 ! response to exogenous dsRNA GO:0043330 10 6 0,000 5,764E-03 0,02871287 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 5,764E-03 0,02865355 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,764E-03 0,02859447 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 5,764E-03 0,02853563 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 5,764E-03 0,02847704 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 5,764E-03 0,02841868 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,764E-03 0,02836057 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,764E-03 0,02830269 ! hair follicle maturation GO:0048820 7 6 0,000 5,764E-03 0,02824504 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 5,764E-03 0,02818764 ! Schwann cell development GO:0014044 15 6 0,000 5,764E-03 0,02813046 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 5,764E-03 0,02807352 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 5,764E-03 0,0280168 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 5,764E-03 0,02796032 ! subpallium development GO:0021544 10 6 0,000 5,764E-03 0,02790406 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 5,764E-03 0,02784803 ! histone ubiquitination GO:0016574 8 6 0,000 5,764E-03 0,02779222 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 5,764E-03 0,02773663 ! maintenance of organ identity GO:0048496 9 6 0,000 5,764E-03 0,02768127 ! G2 phase GO:0051319 16 6 0,000 5,764E-03 0,02762613 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 5,764E-03 0,02757121 ! establishment of planar polarity GO:0001736 7 6 0,000 5,764E-03 0,0275165 ! regulation of mast cell activation GO:0033003 12 6 0,000 5,764E-03 0,02746201 ! membrane to membrane docking GO:0022614 14 6 0,000 5,764E-03 0,02740774 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 5,764E-03 0,02735368 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 5,764E-03 0,02729984 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 5,764E-03 0,0272462 ! receptor internalization GO:0031623 10 6 0,000 5,764E-03 0,02719278 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 5,764E-03 0,02713956 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 5,764E-03 0,02708656 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,764E-03 0,02703376 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 5,764E-03 0,02698116 ! protein deubiquitination GO:0016579 14 6 0,000 5,764E-03 0,02692877 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 5,764E-03 0,02687658 ! protein destabilization GO:0031648 9 6 0,000 5,764E-03 0,0268246 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 5,764E-03 0,02677281 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 5,764E-03 0,02672123 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 5,764E-03 0,02666984 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 5,764E-03 0,02661865 ! progesterone metabolic process GO:0042448 10 6 0,000 5,764E-03 0,02656766 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 5,764E-03 0,02651686 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 5,764E-03 0,02646625 ! negative regulation of axon extension GO:0030517 21 6 0,000 5,764E-03 0,02641584 ! removal of superoxide radicals GO:0019430 11 6 0,000 5,764E-03 0,02636562 ! triglyceride catabolic process GO:0019433 10 6 0,000 5,764E-03 0,02631559 ! determination of adult lifespan GO:0008340 15 6 0,000 5,764E-03 0,02626575 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 5,764E-03 0,0262161 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 5,764E-03 0,02616663 ! cerebellar cortex formation GO:0021697 8 6 0,000 5,764E-03 0,02611736 ! catecholamine transport GO:0051937 9 6 0,000 5,764E-03 0,02606826 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 5,764E-03 0,02601936 ! sensory cilium assembly GO:0035058 10 6 0,000 5,764E-03 0,02597063 ! organ or tissue specific immune response GO:0002251 7 6 0,000 5,764E-03 0,02592209 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 5,764E-03 0,02587372 ! maternal placenta development GO:0001893 12 6 0,000 5,764E-03 0,02582554 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 5,764E-03 0,02577754 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 5,764E-03 0,02572972 ! negative regulation of B cell activation GO:0050869 13 6 0,000 5,764E-03 0,02568207 ! protein amino acid prenylation GO:0018346 16 6 0,000 5,764E-03 0,0256346 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 5,764E-03 0,0255873 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 5,764E-03 0,02554018 ! positive regulation of coagulation GO:0050820 12 6 0,000 5,764E-03 0,02549323 ! tRNA transcription GO:0009304 14 7 0,000 6,722E-03 0,02967374 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 6,722E-03 0,02961939 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 6,722E-03 0,02956524 ! behavioral response to cocaine GO:0048148 14 7 0,000 6,722E-03 0,02951129 ! regulation of helicase activity GO:0051095 15 7 0,000 6,722E-03 0,02945753 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 6,722E-03 0,02940397 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 6,722E-03 0,02935061 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 6,722E-03 0,02929744 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 6,722E-03 0,02924446 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 6,722E-03 0,02919167 ! prostate gland development GO:0030850 13 7 0,000 6,722E-03 0,02913907 ! nucleotide-sugar transport GO:0015780 12 7 0,000 6,722E-03 0,02908667 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,722E-03 0,02903445 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 6,722E-03 0,02898241 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 6,722E-03 0,02893057 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,722E-03 0,0288789 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 6,722E-03 0,02882743 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 6,722E-03 0,02877613 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 6,722E-03 0,02872502 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 6,722E-03 0,02867409 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 6,722E-03 0,02862334 ! SMAD protein complex assembly GO:0007183 12 7 0,000 6,722E-03 0,02857277 ! glycolipid transport GO:0046836 10 7 0,000 6,722E-03 0,02852237 ! protein amino acid sulfation GO:0006477 10 7 0,000 6,722E-03 0,02847216 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 6,722E-03 0,02842212 ! neuron adhesion GO:0007158 12 7 0,000 6,722E-03 0,02837226 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 6,722E-03 0,02832257 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 6,722E-03 0,02827305 ! actin-myosin filament sliding GO:0033275 11 7 0,000 6,722E-03 0,02822371 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 6,722E-03 0,02817454 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 6,722E-03 0,02812554 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 6,722E-03 0,02807671 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 6,722E-03 0,02802805 ! mRNA stabilization GO:0048255 18 7 0,000 6,722E-03 0,02797956 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 6,722E-03 0,02793124 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 6,722E-03 0,02788308 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 6,722E-03 0,02783509 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 6,722E-03 0,02778726 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 6,722E-03 0,0277396 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 6,722E-03 0,0276921 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 6,722E-03 0,02764476 ! lipoprotein transport GO:0042953 14 7 0,000 6,722E-03 0,02759759 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 6,722E-03 0,02755057 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 6,722E-03 0,02750372 ! rhythmic behavior GO:0007622 15 7 0,000 6,722E-03 0,02745702 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 6,722E-03 0,02741049 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 6,722E-03 0,02736411 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 6,722E-03 0,02731788 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 6,722E-03 0,02727181 ! regulation of odontogenesis GO:0042481 13 7 0,000 6,722E-03 0,0272259 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 6,722E-03 0,02718014 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 6,722E-03 0,02713454 ! mechanosensory behavior GO:0007638 14 7 0,000 6,722E-03 0,02708909 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 6,722E-03 0,02704379 ! positive regulation of isotype switching GO:0045830 15 7 0,000 6,722E-03 0,02699864 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 6,722E-03 0,02695364 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,722E-03 0,0269088 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,722E-03 0,0268641 ! spinal cord patterning GO:0021511 13 7 0,000 6,722E-03 0,02681955 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 6,722E-03 0,02677514 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 6,722E-03 0,02673089 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 6,722E-03 0,02668678 ! adrenal gland development GO:0030325 17 7 0,000 6,722E-03 0,02664281 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 6,722E-03 0,02659899 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 6,722E-03 0,02655531 ! ovulation GO:0030728 9 7 0,000 6,722E-03 0,02651178 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 6,722E-03 0,02646839 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 6,722E-03 0,02642514 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 6,722E-03 0,02638203 ! microtubule nucleation GO:0007020 20 7 0,000 6,722E-03 0,02633907 ! proline biosynthetic process GO:0006561 10 7 0,000 6,722E-03 0,02629624 ! thyroid hormone generation GO:0006590 13 7 0,000 6,722E-03 0,02625355 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 6,722E-03 0,026211 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 6,722E-03 0,02616859 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 6,722E-03 0,02612631 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,722E-03 0,02608417 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 6,722E-03 0,02604217 ! galactose metabolic process GO:0006012 13 7 0,000 6,722E-03 0,0260003 ! vesicle fusion GO:0006906 17 7 0,000 6,722E-03 0,02595857 ! response to dietary excess GO:0002021 8 7 0,000 6,722E-03 0,02591697 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 6,722E-03 0,0258755 ! intracellular pH reduction GO:0051452 11 7 0,000 6,722E-03 0,02583416 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 6,722E-03 0,02579296 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 6,722E-03 0,02575189 ! organ growth GO:0035265 15 7 0,000 6,722E-03 0,02571095 ! purine salvage GO:0043101 10 7 0,000 6,722E-03 0,02567014 ! nucleoside transport GO:0015858 8 7 0,000 6,722E-03 0,02562946 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 6,722E-03 0,0255889 ! parturition GO:0007567 14 7 0,000 6,722E-03 0,02554848 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 6,722E-03 0,02550818 ! rRNA modification GO:0000154 14 7 0,000 6,722E-03 0,02546801 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 6,722E-03 0,02542797 ! spindle checkpoint GO:0031577 15 7 0,000 6,722E-03 0,02538805 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 6,722E-03 0,02534825 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 6,722E-03 0,02530859 ! macrophage differentiation GO:0030225 11 7 0,000 6,722E-03 0,02526904 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 6,722E-03 0,02522962 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 6,722E-03 0,02519032 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 6,722E-03 0,02515114 ! hyaluronan metabolic process GO:0030212 8 7 0,000 6,722E-03 0,02511209 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 6,722E-03 0,02507316 ! anterograde axon cargo transport GO:0008089 18 7 0,000 6,722E-03 0,02503434 ! fibrinolysis GO:0042730 10 7 0,000 6,722E-03 0,02499565 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 6,722E-03 0,02495708 ! eating behavior GO:0042755 7 7 0,000 6,722E-03 0,02491862 ! B cell lineage commitment GO:0002326 21 7 0,000 6,722E-03 0,02488029 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 6,722E-03 0,02484207 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 6,722E-03 0,02480397 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 6,722E-03 0,02476598 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 6,722E-03 0,02472811 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 6,722E-03 0,02469036 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 6,722E-03 0,02465272 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 6,722E-03 0,0246152 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 6,722E-03 0,02457779 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 6,722E-03 0,02454049 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 6,722E-03 0,02450331 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 6,722E-03 0,02446624 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 6,722E-03 0,02442928 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 6,722E-03 0,02439244 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 6,722E-03 0,0243557 ! regulation of meiosis GO:0040020 12 7 0,000 6,722E-03 0,02431908 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 6,722E-03 0,02428256 ! T cell lineage commitment GO:0002360 16 7 0,000 6,722E-03 0,02424616 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 6,722E-03 0,02420986 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 6,722E-03 0,02417367 ! oxygen homeostasis GO:0032364 12 7 0,000 6,722E-03 0,02413759 ! transcription termination GO:0006353 13 7 0,000 6,722E-03 0,02410162 ! response to tumor cell GO:0002347 13 7 0,000 6,722E-03 0,02406575 ! regulation of respiratory burst GO:0060263 11 7 0,000 6,722E-03 0,02402999 ! coenzyme A metabolic process GO:0015936 12 7 0,000 6,722E-03 0,02399434 ! anaphase GO:0051322 17 7 0,000 6,722E-03 0,02395879 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 6,722E-03 0,02392335 ! axonal fasciculation GO:0007413 18 7 0,000 6,722E-03 0,02388802 ! negative regulation of nuclear division GO:0051784 14 7 0,000 6,722E-03 0,02385278 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 6,722E-03 0,02381765 ! peptidyl-threonine modification GO:0018210 25 7 0,000 6,722E-03 0,02378263 ! diuresis GO:0030146 12 7 0,000 6,722E-03 0,0237477 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 6,722E-03 0,02371288 ! thiamin metabolic process GO:0006772 7 7 0,000 6,722E-03 0,02367816 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,722E-03 0,02364355 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 6,722E-03 0,02360903 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 6,722E-03 0,02357462 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,722E-03 0,0235403 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 6,722E-03 0,02350608 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 6,722E-03 0,02347197 ! melanin biosynthetic process GO:0042438 8 7 0,000 6,722E-03 0,02343795 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 6,722E-03 0,02340403 ! dopamine biosynthetic process GO:0042416 18 7 0,000 6,722E-03 0,02337021 ! glycolipid catabolic process GO:0019377 15 7 0,000 6,722E-03 0,02333649 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 6,722E-03 0,02330286 ! lymph node development GO:0048535 10 7 0,000 6,722E-03 0,02326933 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 6,722E-03 0,0232359 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 6,722E-03 0,02320256 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 6,722E-03 0,02316932 ! endosome to lysosome transport GO:0008333 11 7 0,000 6,722E-03 0,02313617 ! protein modification by small protein removal GO:0070646 16 7 0,000 6,722E-03 0,02310312 ! adult feeding behavior GO:0008343 9 7 0,000 6,722E-03 0,02307017 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 6,722E-03 0,0230373 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 6,722E-03 0,02300453 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,722E-03 0,02297186 ! muscle adaptation GO:0043500 14 7 0,000 6,722E-03 0,02293927 ! embryonic heart tube development GO:0035050 10 7 0,000 6,722E-03 0,02290678 ! retina homeostasis GO:0001895 12 7 0,000 6,722E-03 0,02287438 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 6,722E-03 0,02284207 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 6,722E-03 0,02280985 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 6,722E-03 0,02277773 ! protein prenylation GO:0018342 18 7 0,000 6,722E-03 0,02274569 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 6,722E-03 0,02271374 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 6,722E-03 0,02268189 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 6,722E-03 0,02265012 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 7,678E-03 0,02583764 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 7,678E-03 0,02580156 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 7,678E-03 0,02576557 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 7,678E-03 0,02572968 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 7,678E-03 0,0256939 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 7,678E-03 0,02565821 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 7,678E-03 0,02562263 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 7,678E-03 0,02558714 ! neutral lipid catabolic process GO:0046461 13 8 0,000 7,678E-03 0,02555175 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 7,678E-03 0,02551645 ! meiotic prophase I GO:0007128 13 8 0,000 7,678E-03 0,02548126 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 7,678E-03 0,02544616 ! oligopeptide transport GO:0006857 15 8 0,000 7,678E-03 0,02541116 ! UTP metabolic process GO:0046051 8 8 0,000 7,678E-03 0,02537625 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 7,678E-03 0,02534144 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 7,678E-03 0,02530673 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 7,678E-03 0,02527211 ! macrophage chemotaxis GO:0048246 12 8 0,000 7,678E-03 0,02523759 ! succinate metabolic process GO:0006105 14 8 0,000 7,678E-03 0,02520316 ! membrane hyperpolarization GO:0060081 10 8 0,000 7,678E-03 0,02516882 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 7,678E-03 0,02513458 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 7,678E-03 0,02510043 ! T-helper 1 type immune response GO:0042088 12 8 0,000 7,678E-03 0,02506637 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 7,678E-03 0,0250324 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 7,678E-03 0,02499853 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 7,678E-03 0,02496475 ! ganglioside metabolic process GO:0001573 19 8 0,000 7,678E-03 0,02493106 ! reflex GO:0060004 16 8 0,000 7,678E-03 0,02489746 ! negative regulation of endocytosis GO:0045806 11 8 0,000 7,678E-03 0,02486395 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 7,678E-03 0,02483053 ! endothelial cell differentiation GO:0045446 17 8 0,000 7,678E-03 0,0247972 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 7,678E-03 0,02476396 ! glycerolipid catabolic process GO:0046503 13 8 0,000 7,678E-03 0,02473081 ! hemoglobin metabolic process GO:0020027 13 8 0,000 7,678E-03 0,02469775 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 7,678E-03 0,02466477 ! pigment granule organization GO:0048753 16 8 0,000 7,678E-03 0,02463188 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 7,678E-03 0,02459909 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 7,678E-03 0,02456637 ! astrocyte differentiation GO:0048708 18 8 0,000 7,678E-03 0,02453375 ! histidine metabolic process GO:0006547 16 8 0,000 7,678E-03 0,02450121 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 7,678E-03 0,02446876 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 7,678E-03 0,02443639 ! glycine catabolic process GO:0006546 13 8 0,000 7,678E-03 0,02440411 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 7,678E-03 0,02437192 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 7,678E-03 0,02433981 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 7,678E-03 0,02430778 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 7,678E-03 0,02427584 ! regulation of pigmentation during development GO:0048070 24 8 0,000 7,678E-03 0,02424398 ! melanin metabolic process GO:0006582 15 8 0,000 7,678E-03 0,02421221 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 7,678E-03 0,02418051 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 7,678E-03 0,02414891 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 7,678E-03 0,02411738 ! macrophage activation GO:0042116 12 8 0,000 7,678E-03 0,02408594 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 7,678E-03 0,02405457 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 7,678E-03 0,02402329 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 7,678E-03 0,0239921 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 7,678E-03 0,02396098 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 7,678E-03 0,02392994 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 7,678E-03 0,02389898 ! regulation of vascular permeability GO:0043114 12 8 0,000 7,678E-03 0,02386811 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 7,678E-03 0,02383731 ! osteoblast development GO:0002076 16 8 0,000 7,678E-03 0,02380659 ! positive regulation of vasodilation GO:0045909 13 8 0,000 7,678E-03 0,02377595 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 7,678E-03 0,02374539 ! negative regulation of translational initiation GO:0045947 10 8 0,000 7,678E-03 0,02371491 ! Schwann cell differentiation GO:0014037 19 8 0,000 7,678E-03 0,0236845 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 7,678E-03 0,02365418 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 7,678E-03 0,02362393 ! response to UV-B GO:0010224 16 8 0,000 7,678E-03 0,02359376 ! protein targeting to vacuole GO:0006623 12 8 0,000 7,678E-03 0,02356367 ! protein retention in ER lumen GO:0006621 14 8 0,000 7,678E-03 0,02353365 ! intermediate filament organization GO:0045109 12 8 0,000 7,678E-03 0,02350371 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 7,678E-03 0,02347384 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 7,678E-03 0,02344405 ! cellular extravasation GO:0045123 12 8 0,000 7,678E-03 0,02341434 ! cardiac muscle cell development GO:0055013 13 8 0,000 7,678E-03 0,0233847 ! regulation of circadian rhythm GO:0042752 16 8 0,000 7,678E-03 0,02335514 ! response to antibiotic GO:0046677 11 8 0,000 7,678E-03 0,02332565 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 7,678E-03 0,02329623 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 7,678E-03 0,02326689 ! DNA topological change GO:0006265 12 8 0,000 7,678E-03 0,02323763 ! response to tropane GO:0014073 15 8 0,000 7,678E-03 0,02320843 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 7,678E-03 0,02317931 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 7,678E-03 0,02315027 ! melanosome transport GO:0032402 13 8 0,000 7,678E-03 0,02312129 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 7,678E-03 0,02309239 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 7,678E-03 0,02306356 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 7,678E-03 0,0230348 ! mast cell activation GO:0045576 14 8 0,000 7,678E-03 0,02300612 ! multicellular organismal aging GO:0010259 18 8 0,000 7,678E-03 0,0229775 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 7,678E-03 0,02294896 ! dendrite morphogenesis GO:0048813 13 8 0,000 7,678E-03 0,02292049 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 7,678E-03 0,02289209 ! nucleosome disassembly GO:0006337 14 8 0,000 7,678E-03 0,02286375 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 7,678E-03 0,02283549 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 7,678E-03 0,0228073 ! leukocyte activation during immune response GO:0002366 13 8 0,000 7,678E-03 0,02277918 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 7,678E-03 0,02275112 ! establishment of chromosome localization GO:0051303 12 8 0,000 7,678E-03 0,02272314 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 7,678E-03 0,02269523 ! intracellular lipid transport GO:0032365 13 8 0,000 7,678E-03 0,02266738 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 7,678E-03 0,0226396 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 7,678E-03 0,02261189 ! regulation of macrophage activation GO:0043030 15 8 0,000 7,678E-03 0,02258425 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 7,678E-03 0,02255667 ! positive regulation of epidermis development GO:0045684 13 8 0,000 7,678E-03 0,02252916 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 7,678E-03 0,02250172 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 7,678E-03 0,02247435 ! hormone catabolic process GO:0042447 17 8 0,000 7,678E-03 0,02244704 ! positive regulation of glucose import GO:0046326 8 8 0,000 7,678E-03 0,0224198 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 7,678E-03 0,02239262 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 7,678E-03 0,02236551 ! ATP catabolic process GO:0006200 11 8 0,000 7,678E-03 0,02233847 ! blastocyst growth GO:0001832 19 8 0,000 7,678E-03 0,02231149 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 7,678E-03 0,02228458 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 7,678E-03 0,02225773 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 7,678E-03 0,02223094 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 7,678E-03 0,02220422 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 7,678E-03 0,02217757 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 7,678E-03 0,02215098 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 7,678E-03 0,02212445 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 7,678E-03 0,02209798 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 7,678E-03 0,02207158 ! amino sugar catabolic process GO:0046348 10 8 0,000 7,678E-03 0,02204524 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 7,678E-03 0,02201897 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 7,678E-03 0,02199275 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 7,678E-03 0,0219666 ! behavioral response to nicotine GO:0035095 12 8 0,000 7,678E-03 0,02194051 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 7,678E-03 0,02191449 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 7,678E-03 0,02188852 ! NAD biosynthetic process GO:0009435 13 8 0,000 7,678E-03 0,02186262 ! regulation of developmental growth GO:0048638 15 9 0,000 8,634E-03 0,02455496 ! axon extension GO:0048675 15 9 0,000 8,634E-03 0,02452597 ! autophagic vacuole formation GO:0000045 15 9 0,000 8,634E-03 0,02449705 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 8,634E-03 0,0244682 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 8,634E-03 0,02443941 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 8,634E-03 0,02441069 ! pentose-phosphate shunt GO:0006098 16 9 0,000 8,634E-03 0,02438204 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 8,634E-03 0,02435346 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 8,634E-03 0,02432494 ! cell proliferation in forebrain GO:0021846 15 9 0,000 8,634E-03 0,02429649 ! phosphate transport GO:0006817 19 9 0,000 8,634E-03 0,02426811 ! reproductive behavior GO:0019098 19 9 0,000 8,634E-03 0,02423979 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 8,634E-03 0,02421154 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 8,634E-03 0,02418335 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 8,634E-03 0,02415523 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 8,634E-03 0,02412718 ! GTP metabolic process GO:0046039 9 9 0,000 8,634E-03 0,02409919 ! RNA methylation GO:0001510 15 9 0,000 8,634E-03 0,02407126 ! elastic fiber assembly GO:0048251 15 9 0,000 8,634E-03 0,0240434 ! induction of positive chemotaxis GO:0050930 15 9 0,000 8,634E-03 0,02401561 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 8,634E-03 0,02398788 ! artery development GO:0060840 24 9 0,000 8,634E-03 0,02396021 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 8,634E-03 0,0239326 ! regulation of glycolysis GO:0006110 21 9 0,000 8,634E-03 0,02390506 ! cerebral cortex cell migration GO:0021795 15 9 0,000 8,634E-03 0,02387759 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 8,634E-03 0,02385017 ! chemosensory behavior GO:0007635 20 9 0,000 8,634E-03 0,02382282 ! microtubule bundle formation GO:0001578 21 9 0,000 8,634E-03 0,02379553 ! middle ear morphogenesis GO:0042474 14 9 0,000 8,634E-03 0,02376831 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 8,634E-03 0,02374114 ! leukocyte degranulation GO:0043299 16 9 0,000 8,634E-03 0,02371404 ! bile acid and bile salt transport GO:0015721 13 9 0,000 8,634E-03 0,023687 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 8,634E-03 0,02366002 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 8,634E-03 0,02363311 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 8,634E-03 0,02360625 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 8,634E-03 0,02357946 ! protein targeting to ER GO:0045047 22 9 0,000 8,634E-03 0,02355272 ! ceramide biosynthetic process GO:0046513 19 9 0,000 8,634E-03 0,02352605 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 8,634E-03 0,02349943 ! T cell selection GO:0045058 23 9 0,000 8,634E-03 0,02347288 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 8,634E-03 0,02344639 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 8,634E-03 0,02341996 ! phosphagen metabolic process GO:0006599 12 9 0,000 8,634E-03 0,02339358 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 8,634E-03 0,02336727 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 8,634E-03 0,02334101 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 8,634E-03 0,02331481 ! regulation of type I interferon production GO:0032479 12 9 0,000 8,634E-03 0,02328868 ! mannose metabolic process GO:0006013 13 9 0,000 8,634E-03 0,0232626 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 8,634E-03 0,02323658 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 8,634E-03 0,02321061 ! Rac protein signal transduction GO:0016601 17 9 0,000 8,634E-03 0,02318471 ! receptor clustering GO:0043113 18 9 0,000 8,634E-03 0,02315886 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 8,634E-03 0,02313307 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 8,634E-03 0,02310734 ! ruffle organization GO:0031529 15 9 0,000 8,634E-03 0,02308167 ! retinol metabolic process GO:0042572 18 9 0,000 8,634E-03 0,02305605 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 8,634E-03 0,02303049 ! behavioral fear response GO:0001662 22 9 0,000 8,634E-03 0,02300498 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 8,634E-03 0,02297954 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 8,634E-03 0,02295414 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 8,634E-03 0,02292881 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 8,634E-03 0,02290353 ! protein heterooligomerization GO:0051291 16 9 0,000 8,634E-03 0,0228783 ! oligodendrocyte development GO:0014003 10 9 0,000 8,634E-03 0,02285314 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 8,634E-03 0,02282802 ! segment specification GO:0007379 13 9 0,000 8,634E-03 0,02280296 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 8,634E-03 0,02277796 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 8,634E-03 0,02275301 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 8,634E-03 0,02272812 ! response to amine stimulus GO:0014075 13 9 0,000 8,634E-03 0,02270328 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 8,634E-03 0,02267849 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 8,634E-03 0,02265376 ! erythrocyte development GO:0048821 15 9 0,000 8,634E-03 0,02262909 ! gas homeostasis GO:0033483 16 9 0,000 8,634E-03 0,02260446 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 8,634E-03 0,02257989 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 8,634E-03 0,02255537 ! renal water homeostasis GO:0003091 14 9 0,000 8,634E-03 0,02253091 ! postreplication repair GO:0006301 22 9 0,000 8,634E-03 0,0225065 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 8,634E-03 0,02248214 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 8,634E-03 0,02245784 ! icosanoid secretion GO:0032309 15 9 0,000 8,634E-03 0,02243359 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 8,634E-03 0,02240939 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 8,634E-03 0,02238524 ! regulation of cell division GO:0051302 15 9 0,000 8,634E-03 0,02236114 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 8,634E-03 0,0223371 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 8,634E-03 0,0223131 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 8,634E-03 0,02228916 ! sterol catabolic process GO:0016127 11 9 0,000 8,634E-03 0,02226527 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 8,634E-03 0,02224143 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 8,634E-03 0,02221765 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 8,634E-03 0,02219391 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 8,634E-03 0,02217022 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 8,634E-03 0,02214659 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 8,634E-03 0,022123 ! musculoskeletal movement GO:0050881 14 9 0,000 8,634E-03 0,02209947 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 8,634E-03 0,02207598 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 8,634E-03 0,02205255 ! regulation of synaptogenesis GO:0051963 15 9 0,000 8,634E-03 0,02202916 ! purine base metabolic process GO:0006144 21 9 0,000 8,634E-03 0,02200583 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 8,634E-03 0,02198254 ! pigment granule transport GO:0051904 17 9 0,000 8,634E-03 0,0219593 ! regulation of fibrinolysis GO:0051917 16 9 0,000 8,634E-03 0,02193611 ! regulation of telomere maintenance GO:0032204 14 9 0,000 8,634E-03 0,02191297 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 8,634E-03 0,02188988 ! regulation of muscle adaptation GO:0043502 14 9 0,000 8,634E-03 0,02186684 ! regulation of amino acid transport GO:0051955 11 9 0,000 8,634E-03 0,02184385 ! mitochondrion localization GO:0051646 15 9 0,000 8,634E-03 0,0218209 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 9,589E-03 0,02420876 ! negative regulation of blood pressure GO:0045776 26 10 0,000 9,589E-03 0,02418338 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 9,589E-03 0,02415806 ! regulation of phosphatase activity GO:0010921 28 10 0,000 9,589E-03 0,02413279 ! synapsis GO:0007129 13 10 0,000 9,589E-03 0,02410757 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 9,589E-03 0,02408241 ! N-glycan processing GO:0006491 20 10 0,000 9,589E-03 0,0240573 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 9,589E-03 0,02403224 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 9,589E-03 0,02400723 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 9,589E-03 0,02398227 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 9,589E-03 0,02395737 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 9,589E-03 0,02393252 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 9,589E-03 0,02390772 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 9,589E-03 0,02388297 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 9,589E-03 0,02385827 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 9,589E-03 0,02383362 ! androgen metabolic process GO:0008209 17 10 0,000 9,589E-03 0,02380903 ! phospholipid efflux GO:0033700 16 10 0,000 9,589E-03 0,02378448 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 9,589E-03 0,02375999 ! positive regulation of heart contraction GO:0045823 16 10 0,000 9,589E-03 0,02373554 ! lung alveolus development GO:0048286 26 10 0,000 9,589E-03 0,02371115 ! pathogenesis GO:0009405 13 10 0,000 9,589E-03 0,02368681 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 9,589E-03 0,02366251 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 9,589E-03 0,02363827 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 9,589E-03 0,02361407 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 9,589E-03 0,02358993 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 9,589E-03 0,02356583 ! endoderm development GO:0007492 16 10 0,000 9,589E-03 0,02354178 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 9,589E-03 0,02351779 ! arginine catabolic process GO:0006527 13 10 0,000 9,589E-03 0,02349384 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 9,589E-03 0,02346994 ! proline metabolic process GO:0006560 13 10 0,000 9,589E-03 0,02344609 ! glucan biosynthetic process GO:0009250 14 10 0,000 9,589E-03 0,02342228 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 9,589E-03 0,02339853 ! polyamine biosynthetic process GO:0006596 12 10 0,000 9,589E-03 0,02337482 ! V(D)J recombination GO:0033151 28 10 0,000 9,589E-03 0,02335116 ! reverse cholesterol transport GO:0043691 16 10 0,000 9,589E-03 0,02332755 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 9,589E-03 0,02330399 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 9,589E-03 0,02328047 ! B cell proliferation GO:0042100 18 10 0,000 9,589E-03 0,023257 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 9,589E-03 0,02323358 ! regulation of sodium ion transport GO:0002028 21 10 0,000 9,589E-03 0,02321021 ! multicellular organism growth GO:0035264 18 10 0,000 9,589E-03 0,02318688 ! phagocytosis, engulfment GO:0006911 28 10 0,000 9,589E-03 0,0231636 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 9,589E-03 0,02314037 ! epithelial cell development GO:0002064 20 10 0,000 9,589E-03 0,02311718 ! lens development in camera-type eye GO:0002088 16 10 0,000 9,589E-03 0,02309404 ! retinoic acid metabolic process GO:0042573 14 10 0,000 9,589E-03 0,02307095 ! macroautophagy GO:0016236 17 10 0,000 9,589E-03 0,0230479 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 9,589E-03 0,0230249 ! positive regulation of translational initiation GO:0045948 11 10 0,000 9,589E-03 0,02300194 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 9,589E-03 0,02297903 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 9,589E-03 0,02295617 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 9,589E-03 0,02293335 ! copper ion homeostasis GO:0055070 13 10 0,000 9,589E-03 0,02291057 ! regulation of bone resorption GO:0045124 25 10 0,000 9,589E-03 0,02288785 ! regulation of gliogenesis GO:0014013 23 10 0,000 9,589E-03 0,02286516 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 9,589E-03 0,02284252 ! alpha-beta T cell activation GO:0046631 23 10 0,000 9,589E-03 0,02281993 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 9,589E-03 0,02279738 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 9,589E-03 0,02277487 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 9,589E-03 0,02275241 ! blastoderm segmentation GO:0007350 18 10 0,000 9,589E-03 0,02273 ! response to dsRNA GO:0043331 20 10 0,000 9,589E-03 0,02270763 ! DNA ligation GO:0006266 19 10 0,000 9,589E-03 0,0226853 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 9,589E-03 0,02266301 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 9,589E-03 0,02264077 ! melanosome localization GO:0032400 16 10 0,000 9,589E-03 0,02261858 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 9,589E-03 0,02259642 ! regulation of B cell differentiation GO:0045577 19 10 0,000 9,589E-03 0,02257431 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 9,589E-03 0,02255225 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 9,589E-03 0,02253022 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 9,589E-03 0,02250824 ! mRNA cleavage GO:0006379 17 10 0,000 9,589E-03 0,0224863 ! protein sumoylation GO:0016925 15 10 0,000 9,589E-03 0,02246441 ! hindbrain morphogenesis GO:0021575 19 10 0,000 9,589E-03 0,02244256 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 9,589E-03 0,02242075 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 9,589E-03 0,02239898 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 9,589E-03 0,02237725 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 9,589E-03 0,02235557 ! salivary gland development GO:0007431 27 10 0,000 9,589E-03 0,02233393 ! prophase GO:0051324 15 10 0,000 9,589E-03 0,02231233 ! negative regulation of neurological system process GO:0031645 19 10 0,000 9,589E-03 0,02229077 ! apical protein localization GO:0045176 15 10 0,000 9,589E-03 0,02226926 ! ubiquinone metabolic process GO:0006743 15 10 0,000 9,589E-03 0,02224778 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 9,589E-03 0,02222635 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 9,589E-03 0,02220496 ! midbrain development GO:0030901 13 10 0,000 9,589E-03 0,0221836 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 9,589E-03 0,02216229 ! methionine biosynthetic process GO:0009086 19 10 0,000 9,589E-03 0,02214103 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 9,589E-03 0,0221198 ! quaternary ammonium group transport GO:0015697 21 10 0,000 9,589E-03 0,02209861 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 9,589E-03 0,02207746 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 9,589E-03 0,02205636 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 9,589E-03 0,02203529 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 9,589E-03 0,02201426 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 9,589E-03 0,02199328 ! oocyte development GO:0048599 17 10 0,000 9,589E-03 0,02197233 ! establishment of pigment granule localization GO:0051905 18 10 0,000 9,589E-03 0,02195143 ! blastocyst formation GO:0001825 17 10 0,000 9,589E-03 0,02193056 ! cerebellar cortex development GO:0021695 15 10 0,000 9,589E-03 0,02190973 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 9,589E-03 0,02188895 ! activation of innate immune response GO:0002218 12 10 0,000 9,589E-03 0,0218682 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 9,589E-03 0,02184749 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 9,589E-03 0,02182682 ! response to nicotine GO:0035094 20 10 0,000 9,589E-03 0,02180619 ! establishment of cell polarity GO:0030010 16 10 0,000 9,589E-03 0,0217856 ! negative regulation of immune effector process GO:0002698 20 10 0,000 9,589E-03 0,02176505 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 9,589E-03 0,02174453 ! localization within membrane GO:0051668 20 10 0,000 9,589E-03 0,02172406 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01054292 0,0238629 ! respiratory burst GO:0045730 17 11 0,000 0,01054292 0,02384047 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01054292 0,02381808 ! neuron fate specification GO:0048665 17 11 0,000 0,01054292 0,02379574 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01054292 0,02377344 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01054292 0,02375118 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01054292 0,02372896 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01054292 0,02370678 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01054292 0,02368465 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01054292 0,02366256 ! response to pain GO:0048265 24 11 0,000 0,01054292 0,0236405 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01054292 0,02361849 ! T cell proliferation GO:0042098 26 11 0,000 0,01054292 0,02359652 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01054292 0,02357459 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01054292 0,0235527 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01054292 0,02353085 ! bone resorption GO:0045453 16 11 0,000 0,01054292 0,02350905 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01054292 0,02348728 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01054292 0,02346555 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01054292 0,02344386 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01054292 0,02342222 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01054292 0,02340061 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01054292 0,02337904 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01054292 0,02335751 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01054292 0,02333603 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01054292 0,02331458 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01054292 0,02329317 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01054292 0,0232718 ! lipid digestion GO:0044241 18 11 0,000 0,01054292 0,02325047 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01054292 0,02322918 ! UV protection GO:0009650 19 11 0,000 0,01054292 0,02320792 ! adult heart development GO:0007512 14 11 0,000 0,01054292 0,02318671 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01054292 0,02316553 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01054292 0,0231444 ! temperature homeostasis GO:0001659 17 11 0,000 0,01054292 0,0231233 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01054292 0,02310224 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01054292 0,02308122 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01054292 0,02306024 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01054292 0,02303929 ! regulation of organ growth GO:0046620 13 11 0,000 0,01054292 0,02301838 ! pigment granule localization GO:0051875 20 11 0,000 0,01054292 0,02299752 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01054292 0,02297668 ! vasoconstriction GO:0042310 18 11 0,000 0,01054292 0,02295589 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01054292 0,02293514 ! embryonic axis specification GO:0000578 18 11 0,000 0,01054292 0,02291442 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01054292 0,02289374 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01054292 0,02287309 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01054292 0,02285249 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01054292 0,02283192 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01054292 0,02281138 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01054292 0,02279089 ! zymogen activation GO:0031638 15 11 0,000 0,01054292 0,02277043 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01054292 0,02275001 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01054292 0,02272962 ! nucleosome positioning GO:0016584 15 11 0,000 0,01054292 0,02270927 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01054292 0,02268896 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01054292 0,02266869 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01054292 0,02264845 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01054292 0,02262824 ! acid secretion GO:0046717 18 11 0,000 0,01054292 0,02260807 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01054292 0,02258794 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01054292 0,02256785 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01054292 0,02254779 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01054292 0,02252776 ! oocyte differentiation GO:0009994 18 11 0,000 0,01054292 0,02250777 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01054292 0,02248782 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,01054292 0,0224679 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01054292 0,02244802 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01054292 0,02242817 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01054292 0,02240836 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01054292 0,02238858 ! embryonic gut development GO:0048566 15 11 0,000 0,01054292 0,02236884 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01054292 0,02234913 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01054292 0,02232945 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01054292 0,02230982 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01054292 0,02229021 ! defense response to fungus GO:0050832 13 11 0,000 0,01054292 0,02227064 ! lysogeny GO:0030069 21 11 0,000 0,01054292 0,02225111 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01054292 0,0222316 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01054292 0,02221214 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01054292 0,0221927 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01054292 0,0221733 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01054292 0,02215394 ! nucleus localization GO:0051647 19 11 0,000 0,01054292 0,02213461 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01054292 0,02211531 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01149603 0,02409359 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01149603 0,02407262 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01149603 0,02405168 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01149603 0,02403079 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01149603 0,02400993 ! virus-host interaction GO:0019048 29 12 0,000 0,01149603 0,0239891 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01149603 0,02396832 ! cartilage condensation GO:0001502 20 12 0,000 0,01149603 0,02394756 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01149603 0,02392685 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01149603 0,02390617 ! protein complex disassembly GO:0043241 27 12 0,000 0,01149603 0,02388552 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01149603 0,02386491 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01149603 0,02384434 ! hippocampus development GO:0021766 26 12 0,000 0,01149603 0,0238238 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01149603 0,0238033 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01149603 0,02378283 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01149603 0,0237624 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01149603 0,02374201 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01149603 0,02372164 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01149603 0,02370132 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01149603 0,02368102 ! drug transport GO:0015893 16 12 0,000 0,01149603 0,02366077 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01149603 0,02364054 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01149603 0,02362036 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01149603 0,0236002 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01149603 0,02358008 ! focal adhesion formation GO:0048041 35 12 0,000 0,01149603 0,02356 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01149603 0,02353995 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01149603 0,02351993 ! forebrain cell migration GO:0021885 21 12 0,000 0,01149603 0,02349995 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01149603 0,02348 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01149603 0,02346008 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01149603 0,0234402 ! entry into host cell GO:0030260 32 12 0,000 0,01149603 0,02342035 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01149603 0,02340054 ! monoamine transport GO:0015844 18 12 0,000 0,01149603 0,02338076 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01149603 0,02336101 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01149603 0,0233413 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01149603 0,02332162 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01149603 0,02330197 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01149603 0,02328235 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01149603 0,02326277 ! protein homotetramerization GO:0051289 21 12 0,000 0,01149603 0,02324322 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01149603 0,02322371 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01149603 0,02320423 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01149603 0,02318477 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01149603 0,02316536 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01149603 0,02314597 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01149603 0,02312662 ! cranial nerve development GO:0021545 20 12 0,000 0,01149603 0,0231073 ! fucose catabolic process GO:0019317 22 12 0,000 0,01149603 0,02308801 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01149603 0,02306875 ! histone acetylation GO:0016573 26 12 0,000 0,01149603 0,02304953 ! histone methylation GO:0016571 26 12 0,000 0,01149603 0,02303034 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01149603 0,02301118 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01149603 0,02299205 ! gland morphogenesis GO:0022612 29 12 0,000 0,01149603 0,02297295 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01149603 0,02295389 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01149603 0,02293486 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01149603 0,02291585 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01149603 0,02289688 ! spleen development GO:0048536 22 12 0,000 0,01149603 0,02287795 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01149603 0,02285904 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01149603 0,02284016 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01149603 0,02282132 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01149603 0,0228025 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01149603 0,02278372 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01149603 0,02276497 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01149603 0,02274625 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01149603 0,02272756 ! response to cold GO:0009409 17 12 0,000 0,01149603 0,0227089 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01149603 0,02269027 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01149603 0,02267167 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01244825 0,02452947 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01244825 0,02450939 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01244825 0,02448935 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01244825 0,02446935 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01244825 0,02444937 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01244825 0,02442943 ! lipid localization GO:0010876 28 13 0,000 0,01244825 0,02440952 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01244825 0,02438964 ! organelle fusion GO:0048284 32 13 0,000 0,01244825 0,0243698 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01244825 0,02434998 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01244825 0,0243302 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01244825 0,02431045 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01244825 0,02429074 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01244825 0,02427105 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01244825 0,0242514 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01244825 0,02423178 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01244825 0,02421219 ! methionine metabolic process GO:0006555 27 13 0,000 0,01244825 0,02419263 ! plasma membrane organization GO:0007009 24 13 0,000 0,01244825 0,02417311 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01244825 0,02415361 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01244825 0,02413415 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01244825 0,02411472 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01244825 0,02409532 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01244825 0,02407595 ! response to X-ray GO:0010165 25 13 0,000 0,01244825 0,02405661 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01244825 0,0240373 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01244825 0,02401803 ! exocrine system development GO:0035272 32 13 0,000 0,01244825 0,02399878 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01244825 0,02397957 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01244825 0,02396038 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01244825 0,02394123 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01244825 0,02392211 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01244825 0,02390302 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01244825 0,02388396 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01244825 0,02386492 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01244825 0,02384592 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01244825 0,02382695 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01244825 0,02380801 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01244825 0,0237891 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01244825 0,02377022 ! ribosome assembly GO:0042255 17 13 0,000 0,01244825 0,02375137 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01244825 0,02373255 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01244825 0,02371376 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01244825 0,023695 ! chromatin silencing GO:0006342 26 13 0,000 0,01244825 0,02367627 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01244825 0,02365757 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01244825 0,0236389 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01244825 0,02362025 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01244825 0,02360164 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01244825 0,02358306 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01244825 0,0235645 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01244825 0,02354598 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01244825 0,02352748 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01244825 0,02350901 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01244825 0,02349057 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01244825 0,02347216 ! embryonic placenta development GO:0001892 23 13 0,000 0,01244825 0,02345378 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01244825 0,02343543 ! insulin secretion GO:0030073 23 13 0,000 0,01244825 0,02341711 ! actin filament polymerization GO:0030041 24 13 0,000 0,01244825 0,02339881 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01244825 0,02338055 ! acrosome reaction GO:0007340 18 13 0,000 0,01244825 0,02336231 ! rRNA transcription GO:0009303 25 14 0,000 0,01339958 0,02512813 ! lactation GO:0007595 26 14 0,000 0,01339958 0,02510856 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01339958 0,02508902 ! reproductive cellular process GO:0048610 20 14 0,000 0,01339958 0,02506951 ! tRNA modification GO:0006400 20 14 0,000 0,01339958 0,02505003 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01339958 0,02503058 ! regulation of S phase GO:0033261 23 14 0,000 0,01339958 0,02501117 ! water transport GO:0006833 21 14 0,000 0,01339958 0,02499178 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01339958 0,02497242 ! non-recombinational repair GO:0000726 25 14 0,000 0,01339958 0,02495309 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01339958 0,02493379 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01339958 0,02491452 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01339958 0,02489528 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01339958 0,02487608 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01339958 0,0248569 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01339958 0,02483775 ! palate development GO:0060021 31 14 0,000 0,01339958 0,02481862 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01339958 0,02479953 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01339958 0,02478047 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01339958 0,02476144 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01339958 0,02474244 ! arginine metabolic process GO:0006525 17 14 0,000 0,01339958 0,02472346 ! regulation of heart rate GO:0002027 24 14 0,000 0,01339958 0,02470452 ! organic alcohol transport GO:0015850 29 14 0,000 0,01339958 0,0246856 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01339958 0,02466671 ! embryo implantation GO:0007566 30 14 0,000 0,01339958 0,02464785 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01339958 0,02462902 ! L-amino acid transport GO:0015807 30 14 0,000 0,01339958 0,02461022 ! bone mineralization GO:0030282 17 14 0,000 0,01339958 0,02459145 ! stem cell development GO:0048864 43 14 0,000 0,01339958 0,02457271 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01339958 0,02455399 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01339958 0,02453531 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01339958 0,02451665 ! cerebellum development GO:0021549 21 14 0,000 0,01339958 0,02449802 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01339958 0,02447942 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01339958 0,02446084 ! response to gamma radiation GO:0010332 28 14 0,000 0,01339958 0,0244423 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01339958 0,02442378 ! cofactor transport GO:0051181 26 14 0,000 0,01339958 0,02440529 ! NADP metabolic process GO:0006739 24 14 0,000 0,01339958 0,02438683 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01339958 0,0243684 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01339958 0,02434999 ! intestinal absorption GO:0050892 25 14 0,000 0,01339958 0,02433162 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01339958 0,02431327 ! oxygen transport GO:0015671 21 14 0,000 0,01339958 0,02429495 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01339958 0,02427665 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01339958 0,02425838 ! regulation of axon extension GO:0030516 37 14 0,000 0,01339958 0,02424015 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01339958 0,02422193 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01435003 0,02592055 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01435003 0,02590111 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,01435003 0,02588169 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01435003 0,02586231 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01435003 0,02584295 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01435003 0,02582362 ! copper ion transport GO:0006825 20 15 0,000 0,01435003 0,02580432 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01435003 0,02578505 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01435003 0,0257658 ! sulfate transport GO:0008272 23 15 0,000 0,01435003 0,02574659 ! response to cAMP GO:0051591 22 15 0,000 0,01435003 0,0257274 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01435003 0,02570825 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01435003 0,02568912 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01435003 0,02567002 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01435003 0,02565095 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01435003 0,02563191 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01435003 0,02561289 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01435003 0,0255939 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01435003 0,02557495 ! pituitary gland development GO:0021983 29 15 0,000 0,01435003 0,02555602 ! vesicle coating GO:0006901 33 15 0,000 0,01435003 0,02553711 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01435003 0,02551824 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01435003 0,02549939 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01435003 0,02548057 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01435003 0,02546178 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01435003 0,02544302 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01435003 0,02542428 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01435003 0,02540558 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01435003 0,0253869 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01435003 0,02536824 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01435003 0,02534962 ! histone deacetylation GO:0016575 20 15 0,000 0,01435003 0,02533102 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01435003 0,02531245 ! tissue regeneration GO:0042246 26 15 0,000 0,01435003 0,0252939 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01435003 0,02527539 ! water homeostasis GO:0030104 27 15 0,000 0,01435003 0,0252569 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01435003 0,02523843 ! muscle maintenance GO:0046716 26 15 0,000 0,01435003 0,02522 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01435003 0,02520159 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01435003 0,02518321 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01435003 0,02516485 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01435003 0,02514652 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01435003 0,02512822 ! cell killing GO:0001906 29 15 0,000 0,01435003 0,02510995 ! detection of bacterium GO:0016045 18 15 0,000 0,01435003 0,0250917 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01435003 0,02507348 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01435003 0,02505528 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01435003 0,02503711 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01435003 0,02501897 ! peptide hormone processing GO:0016486 23 15 0,000 0,01435003 0,02500085 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,0152996 0,02663591 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,0152996 0,02661666 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,0152996 0,02659742 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0152996 0,02657822 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0152996 0,02655904 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0152996 0,02653989 ! bone remodeling GO:0046849 27 16 0,000 0,0152996 0,02652077 ! filopodium assembly GO:0046847 32 16 0,000 0,0152996 0,02650168 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0152996 0,02648261 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0152996 0,02646358 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0152996 0,02644456 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0152996 0,02642558 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0152996 0,02640662 ! startle response GO:0001964 28 16 0,000 0,0152996 0,02638769 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0152996 0,02636879 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0152996 0,02634992 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0152996 0,02633107 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,0152996 0,02631225 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0152996 0,02629345 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0152996 0,02627469 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0152996 0,02625594 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0152996 0,02623723 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0152996 0,02621854 ! response to osmotic stress GO:0006970 25 16 0,000 0,0152996 0,02619988 ! lysosomal transport GO:0007041 26 16 0,000 0,0152996 0,02618125 ! fructose metabolic process GO:0006000 25 16 0,000 0,0152996 0,02616264 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0152996 0,02614406 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0152996 0,0261255 ! intermediate filament-based process GO:0045103 32 16 0,000 0,0152996 0,02610697 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0152996 0,02608847 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0152996 0,02607 ! axon cargo transport GO:0008088 43 16 0,000 0,0152996 0,02605155 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0152996 0,02603312 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0152996 0,02601472 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,0152996 0,02599635 ! DNA replication initiation GO:0006270 27 16 0,000 0,0152996 0,02597801 ! neuron recognition GO:0008038 35 16 0,000 0,0152996 0,02595969 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0152996 0,02594139 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0152996 0,02592312 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0152996 0,02590488 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0152996 0,02588666 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,0152996 0,02586847 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0152996 0,0258503 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0152996 0,02583216 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0152996 0,02581405 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0152996 0,02579596 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0152996 0,0257779 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0152996 0,02575986 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,0152996 0,02574184 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,0152996 0,02572385 ! defense response to virus GO:0051607 37 16 0,000 0,0152996 0,02570589 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01624828 0,02728079 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01624828 0,02726176 ! metencephalon development GO:0022037 30 17 0,000 0,01624828 0,02724276 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01624828 0,02722379 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01624828 0,02720485 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01624828 0,02718593 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01624828 0,02716704 ! signal complex assembly GO:0007172 41 17 0,000 0,01624828 0,02714817 ! endothelial cell migration GO:0043542 28 17 0,000 0,01624828 0,02712933 ! inositol metabolic process GO:0006020 28 17 0,000 0,01624828 0,02711052 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01624828 0,02709173 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01624828 0,02707297 ! glial cell development GO:0021782 27 17 0,000 0,01624828 0,02705423 ! limbic system development GO:0021761 36 17 0,000 0,01624828 0,02703552 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01624828 0,02701684 ! adult walking behavior GO:0007628 33 17 0,000 0,01624828 0,02699818 ! heart looping GO:0001947 30 17 0,000 0,01624828 0,02697955 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01624828 0,02696094 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01624828 0,02694236 ! myoblast differentiation GO:0045445 45 17 0,000 0,01624828 0,02692381 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01624828 0,02690528 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01624828 0,02688677 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01624828 0,02686829 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01624828 0,02684984 ! glycine metabolic process GO:0006544 28 17 0,000 0,01624828 0,02683141 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01624828 0,02681301 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01624828 0,02679463 ! NAD metabolic process GO:0019674 29 17 0,000 0,01624828 0,02677628 ! membrane budding GO:0006900 37 17 0,000 0,01624828 0,02675795 ! DNA integration GO:0015074 29 17 0,000 0,01624828 0,02673965 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01624828 0,02672137 ! regulation of protein binding GO:0043393 33 17 0,000 0,01624828 0,02670312 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01624828 0,02668489 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01624828 0,02666669 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01624828 0,02664851 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01624828 0,02663036 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01624828 0,02661223 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01624828 0,02659413 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01624828 0,02657605 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01624828 0,02655799 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01624828 0,02653996 ! steroid catabolic process GO:0006706 31 17 0,000 0,01624828 0,02652196 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01624828 0,02650398 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01624828 0,02648602 ! gas transport GO:0015669 25 17 0,000 0,01624828 0,02646809 ! organic cation transport GO:0015695 31 17 0,000 0,01624828 0,02645018 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01624828 0,0264323 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01624828 0,02641444 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01624828 0,0263966 ! microspike assembly GO:0030035 36 17 0,000 0,01624828 0,02637879 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01624828 0,026361 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01719608 0,0278799 ! neuron maturation GO:0042551 42 18 0,000 0,01719608 0,02786113 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01719608 0,02784238 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01719608 0,02782365 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01719608 0,02780496 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01719608 0,02778628 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01719608 0,02776763 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01719608 0,02774901 ! memory GO:0007613 31 18 0,000 0,01719608 0,02773041 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01719608 0,02771184 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01719608 0,02769329 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01719608 0,02767477 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01719608 0,02765627 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01719608 0,02763779 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01719608 0,02761934 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01719608 0,02760092 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01719608 0,02758252 ! response to retinoic acid GO:0032526 26 18 0,000 0,01719608 0,02756414 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01719608 0,02754579 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01719608 0,02752746 ! response to fungus GO:0009620 21 18 0,000 0,01719608 0,02750916 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01719608 0,02749088 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01719608 0,02747263 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01719608 0,0274544 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01719608 0,02743619 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01719608 0,02741801 ! vitamin transport GO:0051180 27 18 0,000 0,01719608 0,02739985 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01719608 0,02738172 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01719608 0,02736361 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01719608 0,02734552 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01719608 0,02732746 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01719608 0,02730942 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01719608 0,02729141 ! nerve development GO:0021675 28 18 0,000 0,01719608 0,02727342 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01719608 0,02725545 ! protein secretion GO:0009306 39 19 0,000 0,018143 0,02873737 ! positive regulation of translation GO:0045727 30 19 0,000 0,018143 0,02871846 ! negative regulation of defense response GO:0031348 25 19 0,000 0,018143 0,02869958 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,018143 0,02868072 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,018143 0,02866189 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,018143 0,02864308 ! lipid phosphorylation GO:0046834 35 19 0,000 0,018143 0,0286243 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,018143 0,02860554 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,018143 0,02858681 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,018143 0,0285681 ! bile acid metabolic process GO:0008206 29 19 0,000 0,018143 0,02854942 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,018143 0,02853076 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,018143 0,02851212 ! cerebral cortex development GO:0021987 36 19 0,000 0,018143 0,02849351 ! pigmentation during development GO:0048066 41 19 0,000 0,018143 0,02847493 ! response to vitamin A GO:0033189 27 19 0,000 0,018143 0,02845636 ! heme metabolic process GO:0042168 36 19 0,000 0,018143 0,02843782 ! actin filament bundle formation GO:0051017 42 19 0,000 0,018143 0,02841931 ! neuromuscular junction development GO:0007528 34 19 0,000 0,018143 0,02840082 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,018143 0,02838235 ! plasma membrane fusion GO:0045026 28 19 0,000 0,018143 0,02836391 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,018143 0,02834549 ! peptide cross-linking GO:0018149 37 19 0,000 0,018143 0,0283271 ! protein export from nucleus GO:0006611 36 19 0,000 0,018143 0,02830873 ! heart process GO:0003015 30 19 0,000 0,018143 0,02829038 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,018143 0,02827206 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,018143 0,02825376 ! visual learning GO:0008542 36 19 0,000 0,018143 0,02823549 ! cellular pigmentation GO:0033059 36 19 0,000 0,018143 0,02821723 ! G1 phase GO:0051318 40 19 0,000 0,018143 0,02819901 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,018143 0,0281808 ! cell-cell junction organization GO:0045216 35 19 0,000 0,018143 0,02816262 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,018143 0,02814446 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,018143 0,02812633 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,018143 0,02810822 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,018143 0,02809013 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,018143 0,02807207 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,018143 0,02805402 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,018143 0,02803601 ! cilium assembly GO:0042384 37 19 0,000 0,018143 0,02801801 ! peptide hormone secretion GO:0030072 31 19 0,000 0,018143 0,02800004 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01908904 0,02944117 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01908904 0,02942231 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01908904 0,02940348 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01908904 0,02938466 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01908904 0,02936588 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01908904 0,02934711 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01908904 0,02932837 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01908904 0,02930965 ! response to vitamin GO:0033273 31 20 0,000 0,01908904 0,02929096 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01908904 0,02927229 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01908904 0,02925365 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01908904 0,02923503 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01908904 0,02921643 ! response to alkaloid GO:0043279 38 20 0,000 0,01908904 0,02919786 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01908904 0,02917931 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01908904 0,02916078 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01908904 0,02914228 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01908904 0,0291238 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01908904 0,02910534 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01908904 0,02908691 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01908904 0,0290685 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01908904 0,02905011 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01908904 0,02903175 ! body fluid secretion GO:0007589 31 20 0,000 0,01908904 0,02901341 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01908904 0,02899509 ! peptide secretion GO:0002790 35 20 0,000 0,01908904 0,0289768 ! stem cell differentiation GO:0048863 53 20 0,000 0,01908904 0,02895853 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01908904 0,02894028 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01908904 0,02892206 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01908904 0,02890386 ! sensory perception of pain GO:0019233 30 20 0,000 0,01908904 0,02888568 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01908904 0,02886752 ! diencephalon development GO:0021536 34 20 0,000 0,01908904 0,02884939 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01908904 0,02883128 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01908904 0,02881319 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01908904 0,02879513 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01908904 0,02877709 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01908904 0,02875907 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01908904 0,02874107 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01908904 0,02872309 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01908904 0,02870514 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01908904 0,02868721 ! regulation of glucose import GO:0046324 29 20 0,000 0,01908904 0,02866931 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01908904 0,02865142 ! actin filament-based movement GO:0030048 43 20 0,000 0,01908904 0,02863356 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01908904 0,02861572 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01908904 0,0285979 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01908904 0,0285801 ! negative regulation of translation GO:0017148 29 20 0,000 0,01908904 0,02856233 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01908904 0,02854458 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01908904 0,02852685 ! regulation of cell killing GO:0031341 42 21 0,000 0,0200342 0,02992072 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,0200342 0,02990216 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,0200342 0,02988362 ! hormone secretion GO:0046879 38 21 0,000 0,0200342 0,0298651 ! glycerol metabolic process GO:0006071 34 21 0,000 0,0200342 0,02984661 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,0200342 0,02982814 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,0200342 0,0298097 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,0200342 0,02979127 ! axis specification GO:0009798 38 21 0,000 0,0200342 0,02977287 ! ovarian follicle development GO:0001541 35 21 0,000 0,0200342 0,02975449 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,0200342 0,02973614 ! smooth muscle contraction GO:0006939 46 21 0,000 0,0200342 0,0297178 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,0200342 0,02969949 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,0200342 0,02968121 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,0200342 0,02966294 ! cell aging GO:0007569 44 21 0,000 0,0200342 0,0296447 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,0200342 0,02962648 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,0200342 0,02960828 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,0200342 0,0295901 ! cytolysis GO:0019835 24 21 0,000 0,0200342 0,02957195 ! vasodilation GO:0042311 39 21 0,000 0,0200342 0,02955382 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,0200342 0,02953571 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,0200342 0,02951762 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,0200342 0,02949956 ! oogenesis GO:0048477 36 21 0,000 0,0200342 0,02948152 ! DNA modification GO:0006304 34 21 0,000 0,0200342 0,0294635 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,0200342 0,0294455 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,0200342 0,02942752 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,0200342 0,02940957 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,0200342 0,02939163 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,0200342 0,02937372 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,0200342 0,02935583 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,0200342 0,02933797 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,0200342 0,02932012 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,0200342 0,0293023 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,0200342 0,02928449 ! collagen catabolic process GO:0030574 28 21 0,000 0,0200342 0,02926671 ! sperm-egg recognition GO:0035036 21 21 0,000 0,0200342 0,02924896 ! gut development GO:0048565 39 21 0,000 0,0200342 0,02923122 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02097848 0,03059043 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02097848 0,0305719 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02097848 0,0305534 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02097848 0,03053491 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02097848 0,03051645 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02097848 0,03049801 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02097848 0,0304796 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02097848 0,0304612 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02097848 0,03044283 ! regeneration GO:0031099 41 22 0,000 0,02097848 0,03042448 ! keratinization GO:0031424 28 22 0,000 0,02097848 0,03040615 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02097848 0,03038785 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02097848 0,03036956 ! sensory perception of taste GO:0050909 28 22 0,000 0,02097848 0,0303513 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02097848 0,03033306 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02097848 0,03031484 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02097848 0,03029665 ! vacuolar transport GO:0007034 36 22 0,000 0,02097848 0,03027847 ! lysosome organization GO:0007040 41 22 0,000 0,02097848 0,03026032 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02097848 0,03024219 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02097848 0,03022408 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02097848 0,03020599 ! fucose metabolic process GO:0006004 39 22 0,000 0,02097848 0,03018793 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02097848 0,03016988 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02097848 0,03015186 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02097848 0,03013386 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02097848 0,03011588 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02097848 0,03009792 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,02097848 0,03007998 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02097848 0,03006207 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02097848 0,03004417 ! sarcomere organization GO:0045214 30 22 0,000 0,02097848 0,0300263 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02097848 0,03000845 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02097848 0,02999062 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02097848 0,02997281 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02097848 0,02995502 ! protein stabilization GO:0050821 39 22 0,000 0,02097848 0,02993726 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,02192188 0,03126499 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,02192188 0,03124647 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,02192188 0,03122797 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,02192188 0,03120949 ! gluconeogenesis GO:0006094 33 23 0,000 0,02192188 0,03119103 ! viral genome replication GO:0019079 41 23 0,000 0,02192188 0,0311726 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,02192188 0,03115418 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,02192188 0,03113579 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,02192188 0,03111742 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,02192188 0,03109908 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,02192188 0,03108075 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,02192188 0,03106245 ! visual behavior GO:0007632 42 23 0,000 0,02192188 0,03104416 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,02192188 0,0310259 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,02192188 0,03100766 ! response to ethanol GO:0045471 46 23 0,000 0,02192188 0,03098944 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,02192188 0,03097125 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,02192188 0,03095307 ! peroxisome organization GO:0007031 37 23 0,000 0,02192188 0,03093492 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,02192188 0,03091678 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,02192188 0,03089867 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,02192188 0,03088058 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,02192188 0,03086251 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,02192188 0,03084446 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,02192188 0,03082644 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,02192188 0,03080843 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,02192188 0,03079045 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,02192188 0,03077248 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,02192188 0,03075454 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,02192188 0,03073662 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,02192188 0,03071871 ! fatty acid transport GO:0015908 44 23 0,000 0,02192188 0,03070083 ! platelet activation GO:0030168 37 23 0,000 0,02192188 0,03068297 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,02192188 0,03066514 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,02192188 0,03064732 ! hormone transport GO:0009914 40 23 0,000 0,02192188 0,03062952 ! cell-cell recognition GO:0009988 25 23 0,000 0,02192188 0,03061174 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,02192188 0,03059399 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,02192188 0,03057625 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,02192188 0,03055854 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,02192188 0,03054084 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,02192188 0,03052317 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,0228644 0,03181709 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,0228644 0,03179869 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,0228644 0,03178032 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,0228644 0,03176198 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,0228644 0,03174365 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,0228644 0,03172534 ! vesicle docking GO:0048278 47 24 0,000 0,0228644 0,03170706 ! spinal cord development GO:0021510 47 24 0,000 0,0228644 0,03168879 ! vacuole organization GO:0007033 43 24 0,000 0,0228644 0,03167055 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,0228644 0,03165233 ! digestive system process GO:0022600 39 24 0,000 0,0228644 0,03163412 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,0228644 0,03161594 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,0228644 0,03159778 ! regulation of behavior GO:0050795 43 24 0,000 0,0228644 0,03157965 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,0228644 0,03156153 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,0228644 0,03154343 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,0228644 0,03152535 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,0228644 0,0315073 ! membrane depolarization GO:0051899 39 24 0,000 0,0228644 0,03148926 ! pallium development GO:0021543 49 24 0,000 0,0228644 0,03147125 ! pentose metabolic process GO:0019321 35 24 0,000 0,0228644 0,03145325 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,0228644 0,03143528 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,0228644 0,03141733 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,0228644 0,0313994 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,0228644 0,03138148 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,0228644 0,03136359 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,0228644 0,03134572 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,0228644 0,03132787 ! regulation of amine transport GO:0051952 40 24 0,000 0,0228644 0,03131004 ! protein tetramerization GO:0051262 52 24 0,000 0,0228644 0,03129223 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02380604 0,03256244 ! myelination GO:0042552 45 25 0,000 0,02380604 0,03254394 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02380604 0,03252546 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02380604 0,032507 ! phototransduction GO:0007602 33 25 0,000 0,02380604 0,03248857 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02380604 0,03247015 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02380604 0,03245175 ! sperm motility GO:0030317 31 25 0,000 0,02380604 0,03243338 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02380604 0,03241502 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02380604 0,03239669 ! receptor metabolic process GO:0043112 46 25 0,000 0,02380604 0,03237837 ! chromosome condensation GO:0030261 45 25 0,000 0,02380604 0,03236008 ! response to starvation GO:0042594 42 25 0,000 0,02380604 0,03234181 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02380604 0,03232356 ! neural crest cell development GO:0014032 54 25 0,000 0,02380604 0,03230532 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02380604 0,03228711 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02380604 0,03226892 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02380604 0,03225075 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02380604 0,03223261 ! interaction with host GO:0051701 62 25 0,000 0,02380604 0,03221448 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02380604 0,03219637 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02380604 0,03217828 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02380604 0,03216021 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02380604 0,03214217 ! immunoglobulin production GO:0002377 55 25 0,000 0,02380604 0,03212414 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02380604 0,03210613 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02380604 0,03208815 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02380604 0,03207018 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02380604 0,03205223 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02380604 0,03203431 ! telomere organization GO:0032200 43 25 0,000 0,02380604 0,0320164 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02380604 0,03199851 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,02380604 0,03198065 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02474681 0,03322591 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02474681 0,03320738 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02474681 0,03318887 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02474681 0,03317038 ! initiation of viral infection GO:0019059 57 26 0,000 0,02474681 0,03315191 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02474681 0,03313346 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02474681 0,03311503 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02474681 0,03309663 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02474681 0,03307824 ! molting cycle process GO:0022404 50 26 0,000 0,02474681 0,03305987 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,02474681 0,03304153 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,02474681 0,0330232 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,02474681 0,0330049 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,02474681 0,03298661 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,02474681 0,03296835 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,02474681 0,0329501 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,02474681 0,03293188 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02474681 0,03291367 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02474681 0,03289549 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02474681 0,03287732 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02474681 0,03285918 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,02474681 0,03284105 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02474681 0,03282295 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02474681 0,03280487 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02474681 0,0327868 ! blastocyst development GO:0001824 49 26 0,000 0,02474681 0,03276876 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02474681 0,03275073 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02474681 0,03273273 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,02474681 0,03271474 ! neuron fate commitment GO:0048663 48 27 0,000 0,02568671 0,03393861 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,02568671 0,03391999 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,02568671 0,03390138 ! iron ion transport GO:0006826 59 27 0,000 0,02568671 0,03388279 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,02568671 0,03386423 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,02568671 0,03384568 ! protein amino acid acylation GO:0043543 55 27 0,000 0,02568671 0,03382716 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,02568671 0,03380865 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,02568671 0,03379017 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,02568671 0,0337717 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,02568671 0,03375326 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,02568671 0,03373483 ! autophagy GO:0006914 41 27 0,000 0,02568671 0,03371643 ! male gonad development GO:0008584 44 27 0,000 0,02568671 0,03369805 ! response to toxin GO:0009636 47 27 0,000 0,02568671 0,03367968 ! primary neural tube formation GO:0014020 51 27 0,000 0,02568671 0,03366134 ! base-excision repair GO:0006284 41 27 0,000 0,02568671 0,03364301 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,02568671 0,03362471 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,02568671 0,03360642 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,02568671 0,03358816 ! glutathione metabolic process GO:0006749 39 27 0,000 0,02568671 0,03356992 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,02568671 0,03355169 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,02568671 0,03353349 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,02568671 0,0335153 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,02568671 0,03349714 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02662573 0,03470287 ! circadian rhythm GO:0007623 50 28 0,000 0,02662573 0,03468408 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02662573 0,03466531 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02662573 0,03464656 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,02662573 0,03462784 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02662573 0,03460913 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02662573 0,03459044 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02662573 0,03457177 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02662573 0,03455313 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02662573 0,0345345 ! synaptogenesis GO:0007416 42 28 0,000 0,02662573 0,03451589 ! lipid oxidation GO:0034440 43 28 0,000 0,02662573 0,03449731 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02662573 0,03447874 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,02662573 0,03446019 ! translational initiation GO:0006413 65 29 0,000 0,02756387 0,0356552 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,02756387 0,03563604 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02756387 0,0356169 ! regulation of pH GO:0006885 43 29 0,000 0,02756387 0,03559778 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02756387 0,03557869 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02756387 0,03555961 ! catechol metabolic process GO:0009712 54 29 0,000 0,02756387 0,03554055 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02756387 0,03552152 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02756387 0,0355025 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02756387 0,03548351 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02756387 0,03546453 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02756387 0,03544558 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02756387 0,03542664 ! cell fate determination GO:0001709 60 29 0,000 0,02756387 0,03540773 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02756387 0,03538883 ! detection of light stimulus GO:0009583 38 29 0,000 0,02756387 0,03536996 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,02756387 0,03535111 ! tissue homeostasis GO:0001894 48 29 0,000 0,02756387 0,03533227 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,02756387 0,03531346 ! phenol metabolic process GO:0018958 55 30 0,000 0,02850114 0,03649481 ! zinc ion transport GO:0006829 45 30 0,000 0,02850114 0,0364754 ! membrane docking GO:0022406 61 30 0,000 0,02850114 0,03645601 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02850114 0,03643664 ! cell junction assembly GO:0034329 78 30 0,000 0,02850114 0,03641729 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02850114 0,03639796 ! acute-phase response GO:0006953 49 30 0,000 0,02850114 0,03637865 ! myofibril assembly GO:0030239 47 30 0,000 0,02850114 0,03635936 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02850114 0,03634009 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02850114 0,03632084 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02850114 0,03630161 ! phospholipid transport GO:0015914 51 30 0,000 0,02850114 0,03628241 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02850114 0,03626322 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02850114 0,03624405 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02850114 0,03622491 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02850114 0,03620578 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02850114 0,03618668 ! eye morphogenesis GO:0048592 60 30 0,000 0,02850114 0,03616759 ! response to heat GO:0009408 50 30 0,000 0,02850114 0,03614852 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02943754 0,03731651 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02943754 0,03729686 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02943754 0,03727723 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02943754 0,03725762 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02943754 0,03723803 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02943754 0,03721846 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02943754 0,03719891 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02943754 0,03717939 ! ovulation cycle process GO:0022602 49 31 0,000 0,02943754 0,03715988 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02943754 0,03714039 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02943754 0,03712093 ! peptide transport GO:0015833 55 31 0,000 0,02943754 0,03710148 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02943754 0,03708206 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02943754 0,03706265 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02943754 0,03704327 ! mesoderm formation GO:0001707 69 31 0,000 0,02943754 0,0370239 ! natural killer cell activation GO:0030101 45 31 0,000 0,02943754 0,03700456 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02943754 0,03698524 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02943754 0,03696593 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02943754 0,03694665 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02943754 0,03692739 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02943754 0,03690814 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,03037307 0,03806126 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,03037307 0,03804144 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,03037307 0,03802165 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,03037307 0,03800188 ! cholesterol transport GO:0030301 56 32 0,000 0,03037307 0,03798213 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,03037307 0,03796239 ! spliceosome assembly GO:0000245 67 32 0,000 0,03037307 0,03794268 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,03037307 0,03792299 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,03037307 0,03790332 ! response to ionizing radiation GO:0010212 65 32 0,000 0,03037307 0,03788368 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,03037307 0,03786405 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,03037307 0,03784444 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,03037307 0,03782485 ! muscle cell development GO:0055001 49 32 0,000 0,03037307 0,03780528 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,03037307 0,03778573 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,03037307 0,03776621 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,03037307 0,0377467 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,03037307 0,03772721 ! ovulation cycle GO:0042698 51 32 0,000 0,03037307 0,03770775 ! peripheral nervous system development GO:0007422 64 32 0,000 0,03037307 0,0376883 ! BMP signaling pathway GO:0030509 64 32 0,000 0,03037307 0,03766887 ! hindbrain development GO:0030902 61 32 0,000 0,03037307 0,03764946 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,03037307 0,03763008 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,03037307 0,03761071 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,03037307 0,03759136 ! gene silencing GO:0016458 65 32 0,000 0,03037307 0,03757204 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,03130773 0,03870832 ! post-embryonic development GO:0009791 69 33 0,000 0,03130773 0,03868844 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,03130773 0,03866858 ! protein targeting to membrane GO:0006612 68 33 0,000 0,03130773 0,03864874 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,03130773 0,03862892 ! ceramide metabolic process GO:0006672 64 33 0,000 0,03130773 0,03860912 ! formation of primary germ layer GO:0001704 72 33 0,000 0,03130773 0,03858934 ! sterol transport GO:0015918 57 33 0,000 0,03130773 0,03856958 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,03130773 0,03854984 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,03130773 0,03853013 ! adult locomotory behavior GO:0008344 59 33 0,000 0,03130773 0,03851043 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,03130773 0,03849075 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,03130773 0,03847109 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,03224152 0,03959831 ! glial cell differentiation GO:0010001 63 34 0,000 0,03224152 0,03957811 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,03224152 0,03955792 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,03224152 0,03953776 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,03224152 0,03951762 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,03224152 0,0394975 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,03224152 0,0394774 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,03224152 0,03945732 ! mismatch repair GO:0006298 46 34 0,000 0,03224152 0,03943726 ! spermatid development GO:0007286 63 34 0,000 0,03224152 0,03941722 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,03224152 0,0393972 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,03224152 0,0393772 ! placenta development GO:0001890 53 34 0,000 0,03224152 0,03935723 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,03224152 0,03933727 ! regulation of muscle development GO:0048634 70 35 0,000 0,03317444 0,04045499 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,03317444 0,0404345 ! negative regulation of secretion GO:0051048 63 35 0,000 0,03317444 0,04041402 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,03317444 0,04039357 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,03317444 0,04037314 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,03317444 0,04035273 ! female gonad development GO:0008585 58 35 0,000 0,03317444 0,04033234 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,03317444 0,04031197 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,03317444 0,04029162 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,03317444 0,04027129 ! cytokine production GO:0001816 59 35 0,000 0,03317444 0,04025098 ! neural tube formation GO:0001841 67 35 0,000 0,03317444 0,04023069 ! vesicle localization GO:0051648 64 35 0,000 0,03317444 0,04021042 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,03410649 0,04131934 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,03410649 0,04129854 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03410649 0,04127777 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03410649 0,04125702 ! cell junction organization GO:0034330 86 36 0,000 0,03410649 0,04123628 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03410649 0,04121557 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,03410649 0,04119488 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03410649 0,04117421 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03410649 0,04115356 ! regulation of proteolysis GO:0030162 72 36 0,000 0,03410649 0,04113294 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03410649 0,04111233 ! aerobic respiration GO:0009060 55 36 0,000 0,03410649 0,04109174 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,03410649 0,04107117 ! embryonic organ development GO:0048568 57 36 0,000 0,03410649 0,04105063 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,03410649 0,0410301 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03410649 0,0410096 ! RNA export from nucleus GO:0006405 56 37 0,000 0,03503767 0,04210821 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,03503767 0,04208719 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,03503767 0,04206618 ! sister chromatid segregation GO:0000819 58 37 0,000 0,03503767 0,0420452 ! actomyosin structure organization GO:0031032 62 37 0,000 0,03503767 0,04202424 ! organic anion transport GO:0015711 68 37 0,000 0,03503767 0,0420033 ! tissue remodeling GO:0048771 76 37 0,000 0,03503767 0,04198239 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03503767 0,04196149 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,03503767 0,04194061 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03503767 0,04191976 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03503767 0,04189892 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03503767 0,04187811 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03503767 0,04185732 ! glycogen metabolic process GO:0005977 61 37 0,000 0,03503767 0,04183654 ! pigment metabolic process GO:0042440 80 37 0,000 0,03503767 0,04181579 ! spermatid differentiation GO:0048515 66 37 0,000 0,03503767 0,04179506 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,03503767 0,04177435 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,03596799 0,04286229 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,03596799 0,04284108 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,03596799 0,04281988 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,03596799 0,0427987 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,03596799 0,04277754 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,03596799 0,04275641 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,03596799 0,0427353 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,03596799 0,0427142 ! lipid homeostasis GO:0055088 67 38 0,000 0,03596799 0,04269313 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,03596799 0,04267208 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,03596799 0,04265105 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,03596799 0,04263004 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,03596799 0,04260905 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,03596799 0,04258808 ! glucan metabolic process GO:0044042 62 38 0,000 0,03596799 0,04256713 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,03689744 0,04364564 ! mammary gland development GO:0030879 86 39 0,000 0,03689744 0,04362419 ! learning GO:0007612 77 39 0,000 0,03689744 0,04360277 ! organic ether metabolic process GO:0018904 55 39 0,000 0,03689744 0,04358136 ! segmentation GO:0035282 67 39 0,000 0,03689744 0,04355998 ! ion transmembrane transport GO:0034220 66 39 0,000 0,03689744 0,04353861 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,03689744 0,04351727 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,03689744 0,04349595 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,03689744 0,04347465 ! RNA modification GO:0009451 57 39 0,000 0,03689744 0,04345337 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,03689744 0,04343211 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,03782602 0,04450338 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,03782602 0,04448163 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,03782602 0,0444599 ! feeding behavior GO:0007631 59 40 0,000 0,03782602 0,04443819 ! negative regulation of binding GO:0051100 72 40 0,000 0,03782602 0,0444165 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,03782602 0,04439483 ! mesenchymal cell development GO:0014031 87 40 0,000 0,03782602 0,04437319 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,03782602 0,04435156 ! maintenance of protein location GO:0045185 91 40 0,000 0,03782602 0,04432996 ! cytokinesis GO:0000910 72 40 0,000 0,03782602 0,04430838 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03875374 0,04537299 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03875374 0,04535092 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03875374 0,04532888 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03875374 0,04530685 ! gliogenesis GO:0042063 88 41 0,000 0,03875374 0,04528485 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03875374 0,04526286 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03875374 0,0452409 ! T cell differentiation GO:0030217 81 41 0,000 0,03875374 0,04521896 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03875374 0,04519704 ! female gamete generation GO:0007292 61 41 0,000 0,03875374 0,04517515 ! polyol metabolic process GO:0019751 66 41 0,000 0,03875374 0,04515327 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,03875374 0,04513141 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,0396806 0,04618845 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,0396806 0,04616611 ! regulation of tube size GO:0035150 71 42 0,000 0,0396806 0,0461438 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,0396806 0,04612151 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,0396806 0,04609924 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,0396806 0,04607699 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,0396806 0,04605476 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,0396806 0,04603255 ! neuron migration GO:0001764 79 42 0,000 0,0396806 0,04601037 ! regulation of protein secretion GO:0050708 71 42 0,000 0,0396806 0,04598821 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,0396806 0,04596607 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,04060659 0,0470161 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,04060659 0,04699349 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,04060659 0,04697089 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,04060659 0,04694832 ! glucose transport GO:0015758 65 43 0,000 0,04060659 0,04692577 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,04060659 0,04690324 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,04060659 0,04688074 ! neural tube development GO:0021915 77 43 0,000 0,04060659 0,04685825 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,04060659 0,04683579 ! striated muscle contraction GO:0006941 77 43 0,000 0,04060659 0,04681335 ! phagocytosis GO:0006909 90 43 0,000 0,04060659 0,04679093 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,04060659 0,04676853 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,04153172 0,04781116 ! hexose transport GO:0008645 67 44 0,000 0,04153172 0,0477883 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,04153172 0,04776545 ! double-strand break repair GO:0006302 81 44 0,000 0,04153172 0,04774263 ! biopolymer methylation GO:0043414 84 44 0,000 0,04153172 0,04771983 ! B cell differentiation GO:0030183 107 44 0,000 0,04153172 0,04769705 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,04153172 0,0476743 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,04153172 0,04765156 ! developmental growth GO:0048589 82 44 0,000 0,04153172 0,04762885 ! maintenance of location in cell GO:0051651 97 44 0,000 0,04153172 0,04760616 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,04245599 0,04864244 ! glycolysis GO:0006096 65 45 0,000 0,04245599 0,04861929 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,04245599 0,04859616 ! leukocyte migration GO:0050900 68 45 0,000 0,04245599 0,04857305 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,04245599 0,04854996 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,04245599 0,0485269 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,04245599 0,04850386 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,04245599 0,04848084 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,04245599 0,04845784 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,04245599 0,04843486 ! cell growth GO:0016049 84 45 0,000 0,04245599 0,0484119 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,0433794 0,04944142 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,0433794 0,04941801 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,0433794 0,04939463 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,0433794 0,04937126 ! pigmentation GO:0043473 100 46 0,000 0,0433794 0,04934792 ! response to insulin stimulus GO:0032868 95 46 0,000 0,0433794 0,0493246 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,0433794 0,0493013 ! positive regulation of defense response GO:0031349 76 47 0,000 0,04430195 0,05032601 ! endosome transport GO:0016197 108 47 0,000 0,04430195 0,05030226 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,04430195 0,05027854 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,04430195 0,05025483 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,04430195 0,05023115 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,04430195 0,05020749 ! JNK cascade GO:0007254 91 47 0,000 0,04430195 0,05018385 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,04430195 0,05016023 ! methylation GO:0032259 90 47 0,000 0,04430195 0,05013664 ! protein homooligomerization GO:0051260 76 47 0,000 0,04430195 0,05011307 ! mitochondrial transport GO:0006839 82 48 0,000 0,04522364 0,05113162 ! Notch signaling pathway GO:0007219 96 48 0,000 0,04522364 0,0511076 ! cellular component disassembly GO:0022411 86 48 0,000 0,04522364 0,05108361 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,04522364 0,05105964 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,04522364 0,05103569 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,04522364 0,05101176 ! activation of caspase activity GO:0006919 84 48 0,000 0,04522364 0,05098786 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,04522364 0,05096397 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,04522364 0,05094012 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,04522364 0,05091628 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,04614448 0,05192872 ! regulation of action potential GO:0001508 95 49 0,000 0,04614448 0,05190445 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,04614448 0,05188019 ! regulation of ion transport GO:0043269 77 49 0,000 0,04614448 0,05185596 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,04614448 0,05183175 ! peptide metabolic process GO:0006518 76 49 0,000 0,04614448 0,05180756 ! response to temperature stimulus GO:0009266 76 49 0,000 0,04614448 0,0517834 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,04614448 0,05175926 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,04614448 0,05173514 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,04614448 0,05171104 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,04614448 0,05168697 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,04614448 0,05166292 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,04706445 0,0526684 ! neuromuscular process GO:0050905 99 50 0,000 0,04706445 0,05264392 ! regulation of ossification GO:0030278 117 50 0,000 0,04706445 0,05261946 ! histone modification GO:0016570 91 50 0,000 0,04706445 0,05259502 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,04706445 0,0525706 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,04706445 0,0525462 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,04706445 0,05252183 ! positive regulation of binding GO:0051099 78 51 0,000 0,04798357 0,0535227 ! viral infectious cycle GO:0019058 99 51 0,000 0,04798357 0,0534979 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,04798357 0,05347312 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,04798357 0,05344836 ! excretion GO:0007588 83 51 0,000 0,04798357 0,05342363 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,04798357 0,05339892 ! chromatin remodeling GO:0006338 109 51 0,000 0,04798357 0,05337423 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,04798357 0,05334957 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,04798357 0,05332493 ! vesicle organization GO:0016050 107 51 0,000 0,04798357 0,05330031 ! regulation of cell shape GO:0008360 125 51 0,000 0,04798357 0,05327571 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,04890183 0,05427021 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,04890183 0,05424519 ! membrane fusion GO:0006944 110 52 0,000 0,04890183 0,05422019 ! covalent chromatin modification GO:0016569 101 52 0,000 0,04890183 0,05419521 ! amino acid activation GO:0043038 92 52 0,000 0,04890183 0,05417026 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,04890183 0,05414533 ! synapse organization GO:0050808 85 52 0,000 0,04890183 0,05412043 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,04981924 0,05511039 ! RNA catabolic process GO:0006401 93 53 0,000 0,04981924 0,05508506 ! regulation of translational initiation GO:0006446 82 53 0,000 0,04981924 0,05505976 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,04981924 0,05503448 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,04981924 0,05500922 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,04981924 0,05498399 ! cell maturation GO:0048469 100 53 0,000 0,04981924 0,05495878 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,04981924 0,05493359 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,04981924 0,05490842 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,05073579 0,055893 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,05073579 0,05586742 ! cell recognition GO:0008037 85 54 0,000 0,05073579 0,05584186 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,05073579 0,05581633 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,05073579 0,05579082 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,05073579 0,05576533 ! chloride transport GO:0006821 90 55 0,000 0,05165149 0,05674588 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,05165149 0,05671998 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,05165149 0,05669411 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,05165149 0,05666826 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,05165149 0,05664243 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,05165149 0,05661662 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,05165149 0,05659084 ! aging GO:0007568 103 55 0,000 0,05165149 0,05656508 ! gastrulation GO:0007369 112 55 0,000 0,05165149 0,05653935 ! heart morphogenesis GO:0003007 97 55 0,000 0,05165149 0,05651364 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,05165149 0,05648795 ! RNA elongation GO:0006354 79 55 0,000 0,05165149 0,05646228 ! nuclear export GO:0051168 97 55 0,000 0,05165149 0,05643664 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,05165149 0,05641102 ! regulation of actin filament length GO:0030832 105 56 0,000 0,05256634 0,05738412 ! sensory perception of smell GO:0007608 80 56 0,000 0,05256634 0,0573581 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,05256634 0,0573321 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,05256634 0,05730612 ! proton transport GO:0015992 94 56 0,000 0,05256634 0,05728017 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,05256634 0,05725424 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,05348033 0,05822338 ! lipid modification GO:0030258 97 57 0,000 0,05348033 0,05819705 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,05348033 0,05817074 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,05348033 0,05814445 ! maintenance of location GO:0051235 118 57 0,000 0,05348033 0,05811819 ! hydrogen transport GO:0006818 97 58 0,000 0,05439347 0,05908384 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,05439347 0,05905717 ! regulation of endocytosis GO:0030100 91 58 0,000 0,05439347 0,05903054 ! adult behavior GO:0030534 99 58 0,000 0,05439347 0,05900392 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,05439347 0,05897733 ! positive regulation of secretion GO:0051047 95 59 0,000 0,05530577 0,05993949 ! regulation of cellular component size GO:0032535 109 59 0,000 0,05530577 0,0599125 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,05530577 0,05988554 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,05530577 0,0598586 ! DNA catabolic process GO:0006308 86 59 0,000 0,05530577 0,05983169 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,05530577 0,0598048 ! establishment of organelle localization GO:0051656 109 59 0,000 0,05530577 0,05977793 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,05621721 0,06073579 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,05621721 0,06070853 ! regulation of heart contraction GO:0008016 110 60 0,000 0,05621721 0,06068129 ! camera-type eye development GO:0043010 116 60 0,000 0,05621721 0,06065408 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,05621721 0,0606269 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,0571278 0,06158131 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,0571278 0,06155374 ! mesoderm development GO:0007498 119 61 0,000 0,0571278 0,06152618 ! tRNA processing GO:0008033 89 61 0,000 0,0571278 0,06149865 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,0571278 0,06147115 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,0571278 0,06144367 ! viral reproductive process GO:0022415 126 62 0,000 0,05803755 0,06239425 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,05803755 0,06236639 ! gonad development GO:0008406 98 62 0,000 0,05803755 0,06233854 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,05803755 0,06231073 ! regulation of mitosis GO:0007088 105 63 0,000 0,05894644 0,06325832 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,05894644 0,06323011 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,05894644 0,06320194 ! detection of external stimulus GO:0009581 91 63 0,000 0,05894644 0,06317378 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,05894644 0,06314566 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,05894644 0,06311755 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,05985449 0,06406135 ! cell redox homeostasis GO:0045454 102 64 0,000 0,05985449 0,06403287 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,05985449 0,06400441 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,05985449 0,06397597 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,05985449 0,06394756 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0607617 0,06488799 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0607617 0,06485921 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,0607617 0,06483044 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,0607617 0,06480171 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,0607617 0,06477299 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,06166806 0,06571007 ! actin filament organization GO:0007015 148 66 0,000 0,06166806 0,06568099 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,06166806 0,06565192 ! secondary metabolic process GO:0019748 116 66 0,000 0,06166806 0,06562289 ! developmental maturation GO:0021700 116 66 0,000 0,06166806 0,06559388 ! cell projection assembly GO:0030031 120 66 0,000 0,06166806 0,06556489 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,06257357 0,06649824 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,06257357 0,06646888 ! activation of MAPK activity GO:0000187 115 67 0,000 0,06257357 0,06643955 ! chromosome segregation GO:0007059 113 67 0,000 0,06257357 0,06641024 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,06257357 0,06638096 ! hexose catabolic process GO:0019320 104 67 0,000 0,06257357 0,0663517 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,06257357 0,06632247 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,06257357 0,06629327 ! adaptive immune response GO:0002250 119 67 0,000 0,06257357 0,06626409 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,06257357 0,06623494 ! amino acid transport GO:0006865 125 68 0,000 0,06347824 0,067163 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,06347824 0,06713348 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,06347824 0,06710398 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,06347824 0,06707451 ! viral reproduction GO:0016032 134 68 0,000 0,06347824 0,06704506 ! regulation of lipase activity GO:0060191 130 68 0,000 0,06347824 0,06701565 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,06347824 0,06698625 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,06438207 0,06791024 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,06438207 0,06788048 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,06438207 0,06785075 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,06438207 0,06782104 ! antigen processing and presentation GO:0019882 104 69 0,000 0,06438207 0,06779136 ! appendage morphogenesis GO:0035107 135 70 0,000 0,06528506 0,0687121 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,0661872 0,06963114 ! reproductive structure development GO:0048608 113 71 0,000 0,0661872 0,0696007 ! appendage development GO:0048736 136 71 0,000 0,0661872 0,0695703 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,0661872 0,06953992 ! B cell activation GO:0042113 160 71 0,000 0,0661872 0,06950956 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,0661872 0,06947924 ! regulation of immune effector process GO:0002697 137 71 0,000 0,0661872 0,06944894 ! acute inflammatory response GO:0002526 113 72 0,000 0,06708851 0,07036397 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,06708851 0,07033331 ! carbohydrate transport GO:0008643 110 72 0,000 0,06708851 0,07030268 ! learning or memory GO:0007611 147 73 0,000 0,06798897 0,07121526 ! regulation of blood pressure GO:0008217 125 73 0,000 0,06798897 0,07118427 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,06798897 0,07115331 ! axon guidance GO:0007411 139 73 0,000 0,06798897 0,07112237 ! fertilization GO:0009566 90 73 0,000 0,06798897 0,07109147 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,06888859 0,07200085 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,06888859 0,07196959 ! neurotransmitter transport GO:0006836 123 74 0,000 0,06888859 0,07193835 ! exocytosis GO:0006887 133 74 0,000 0,06888859 0,07190714 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,06888859 0,07187596 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,06888859 0,0718448 ! eye development GO:0001654 143 74 0,000 0,06888859 0,07181367 ! organelle localization GO:0051640 136 74 0,000 0,06888859 0,07178257 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,06978738 0,07268764 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,06978738 0,07265618 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,06978738 0,07262476 ! rhythmic process GO:0048511 128 75 0,000 0,06978738 0,07259336 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,06978738 0,07256199 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,07068533 0,07346389 ! defense response to bacterium GO:0042742 89 76 0,000 0,07068533 0,07343217 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,07068533 0,07340048 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,07068533 0,07336881 ! regulation of catabolic process GO:0009894 161 76 0,000 0,07068533 0,07333717 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,07158244 0,07423593 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,07158244 0,07420394 ! blood coagulation GO:0007596 146 78 0,000 0,07247872 0,07510069 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,07247872 0,07506836 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,07247872 0,07503605 ! protein oligomerization GO:0051259 139 78 0,000 0,07247872 0,07500378 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,07337416 0,07589777 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,07337416 0,07586516 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,07337416 0,07583257 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,07337416 0,07580001 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,07426876 0,07669126 ! muscle cell differentiation GO:0042692 159 80 0,000 0,07426876 0,07665836 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,07426876 0,07662549 ! protein import into nucleus GO:0006606 158 80 0,000 0,07426876 0,07659264 ! inorganic anion transport GO:0015698 138 80 0,000 0,07426876 0,07655983 ! T cell activation GO:0042110 168 81 0,000 0,07516253 0,07744799 ! response to hypoxia GO:0001666 171 81 0,000 0,07516253 0,07741483 ! digestion GO:0007586 112 81 0,000 0,07516253 0,07738171 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,07516253 0,07734861 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,07516253 0,07731554 ! nuclear import GO:0051170 161 81 0,000 0,07516253 0,0772825 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,07605547 0,07816722 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,07605547 0,07813384 ! response to drug GO:0042493 143 82 0,000 0,07605547 0,0781005 ! response to nutrient GO:0007584 125 82 0,000 0,07605547 0,07806718 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,07605547 0,07803389 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,07605547 0,07800062 ! response to oxygen levels GO:0070482 176 83 0,000 0,07694758 0,07888192 ! regulation of lyase activity GO:0051339 160 83 0,000 0,07694758 0,07884833 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,07783885 0,07972766 ! hemostasis GO:0007599 158 84 0,000 0,07783885 0,07969373 ! negative regulation of transport GO:0051051 153 84 0,000 0,07783885 0,07965984 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,07783885 0,07962597 ! nucleosome assembly GO:0006334 122 85 0,000 0,07872929 0,08050263 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,07872929 0,08046843 ! amine biosynthetic process GO:0009309 138 86 0,000 0,07961891 0,08134314 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,07961891 0,08130861 ! chromatin assembly GO:0031497 124 86 0,000 0,07961891 0,08127411 ! alcohol catabolic process GO:0046164 130 86 0,000 0,07961891 0,08123965 ! amine transport GO:0015837 155 86 0,000 0,07961891 0,08120521 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,08050769 0,08207691 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,08050769 0,08204214 ! protein localization in nucleus GO:0034504 176 87 0,000 0,08050769 0,08200741 ! regulation of protein transport GO:0051223 154 87 0,000 0,08050769 0,0819727 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,08139564 0,08284176 ! regulation of DNA binding GO:0051101 155 88 0,000 0,08139564 0,08280673 ! regulation of neurological system process GO:0031644 148 88 0,000 0,08139564 0,08277173 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,08139564 0,08273676 ! cellular defense response GO:0006968 114 89 0,000 0,08228277 0,08360319 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,08228277 0,0835679 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,08228277 0,08353263 ! ossification GO:0001503 188 90 0,000 0,08316907 0,08439679 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,08316907 0,08436121 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,08316907 0,08432566 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,08316907 0,08429014 ! bone development GO:0060348 189 91 0,000 0,08405454 0,08515168 ! sterol metabolic process GO:0016125 152 91 0,000 0,08405454 0,08511584 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,08405454 0,08508003 ! regulation of defense response GO:0031347 149 92 0,000 0,08493919 0,08593931 ! nucleosome organization GO:0034728 138 92 0,000 0,08493919 0,08590319 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,08493919 0,0858671 ! vitamin metabolic process GO:0006766 139 92 0,000 0,08493919 0,08583103 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,08582301 0,08668773 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,08582301 0,08665135 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,08582301 0,086615 ! regulation of membrane potential GO:0042391 164 93 0,000 0,08582301 0,08657869 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,08582301 0,0865424 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,08670601 0,08739617 ! female pregnancy GO:0007565 164 94 0,000 0,08670601 0,08735957 ! transcription initiation GO:0006352 153 94 0,000 0,08670601 0,08732301 ! regulation of T cell activation GO:0050863 158 94 0,000 0,08670601 0,08728647 ! forebrain development GO:0030900 188 95 0,000 0,08758818 0,08813767 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,08758818 0,08810082 ! leukocyte differentiation GO:0002521 202 96 0,000 0,08846954 0,08895015 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,08846954 0,08891299 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,08846954 0,08887587 ! positive regulation of immune response GO:0050778 156 96 0,000 0,08846954 0,08883877 ! detection of stimulus GO:0051606 151 96 0,000 0,08846954 0,08880171 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,08935007 0,08964815 ! protein ubiquitination GO:0016567 217 97 0,000 0,08935007 0,08961078 ! hormone metabolic process GO:0042445 157 97 0,000 0,08935007 0,08957344 ! regulation of protein localization GO:0032880 176 97 0,000 0,08935007 0,08953613 ! response to virus GO:0009615 160 98 0,000 0,09022977 0,09038003 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,09022977 0,09034242 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,09022977 0,09030484 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,09110866 0,09114655 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,09110866 0,09110866