pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/9612-11-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 1,431E-05 0,02638188 ! positive regulation of cell growth GO:0030307 6 6 1,000 1,771E-05 0,01631737 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 1,771E-05 0,01087825 ! regulation of Rho GTPase activity GO:0032319 6 6 1,000 1,771E-05 8,159E-03 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 1,771E-05 6,527E-03 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 2,478E-05 7,61E-03 ! keratinocyte proliferation GO:0043616 7 7 1,000 2,478E-05 6,523E-03 ! UV protection GO:0009650 7 7 1,000 2,478E-05 5,708E-03 ! regulation of stress fiber formation GO:0051492 9 8 1,000 3,302E-05 6,761E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 3,302E-05 6,085E-03 ! positive regulation of cell size GO:0045793 9 9 1,000 4,242E-05 7,108E-03 ! negative regulation of caspase activity GO:0043154 9 9 1,000 4,242E-05 6,516E-03 ! regulation of dephosphorylation GO:0035303 9 9 1,000 4,242E-05 6,014E-03 ! regulation of actin filament bundle formation GO:0032231 10 9 1,000 4,242E-05 5,585E-03 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 5,3E-05 6,512E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 5,3E-05 6,105E-03 ! skin development GO:0043588 11 11 1,000 6,474E-05 7,018E-03 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 7,764E-05 7,95E-03 ! negative regulation of translation GO:0017148 12 12 1,000 7,764E-05 7,531E-03 ! negative regulation of protein modification process GO:0031400 13 13 1,000 9,17E-05 8,451E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 1,000 9,17E-05 8,048E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 9,17E-05 7,682E-03 GO:0001952|regulation of cell-matrix adhesion, ! base-excision repair GO:0006284 14 14 1,000 1,069E-04 8,568E-03 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 1,595E-04 0,01225002 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 1,794E-04 0,01322232 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 2,457E-04 0,01741982 ! RNA export from nucleus GO:0006405 22 22 1,000 2,702E-04 0,01844137 ! positive regulation of growth GO:0045927 23 23 1,000 2,957E-04 0,01946501 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 3,792E-04 0,02410011 ! double-strand break repair GO:0006302 27 26 1,000 3,792E-04 0,02329677 ! response to insulin stimulus GO:0032868 28 26 1,000 3,792E-04 0,02254526 ! keratinocyte differentiation GO:0030216 28 28 1,000 4,405E-04 0,02537288 ! response to UV GO:0009411 29 29 1,000 4,729E-04 0,02641114 ! regulation of DNA replication GO:0006275 32 31 1,000 5,41E-04 0,02932536 ! epidermal cell differentiation GO:0009913 31 31 1,000 5,41E-04 0,02848749 ! nuclear export GO:0051168 32 32 1,000 5,767E-04 0,02952538 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 6,516E-04 0,03245425 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 6,906E-04 0,03349584 ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 7,721E-04 0,03648894 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 7,721E-04 0,03557672 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 7,721E-04 0,03470899 ! negative regulation of kinase activity GO:0033673 38 38 1,000 8,146E-04 0,03574413 ! nucleotide-excision repair GO:0006289 40 39 1,000 8,581E-04 0,03677862 ! negative regulation of transferase activity GO:0051348 40 40 1,000 9,027E-04 0,03781244 ! regulation of caspase activity GO:0043281 41 41 1,000 9,485E-04 0,03884553 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 9,485E-04 0,03800107 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 9,953E-04 0,03902942 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 9,953E-04 0,0382163 ! mitochondrion organization GO:0007005 44 43 1,000 1,043E-03 0,03923968 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 1,092E-03 0,04026261 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 1,142E-03 0,04128504 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 1,142E-03 0,0404911 ! regulation of actin filament-based process GO:0032970 47 46 1,000 1,194E-03 0,0415087 ! regulation of peptidase activity GO:0052547 46 46 1,000 1,194E-03 0,04074002 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 1,194E-03 0,0399993 ! positive regulation of ligase activity GO:0051351 47 46 1,000 1,194E-03 0,03928502 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 1,299E-03 0,04201485 ! regulation of ligase activity GO:0051340 50 49 1,000 1,354E-03 0,04302242 ! regulation of DNA metabolic process GO:0051052 51 50 1,000 1,41E-03 0,04402978 ! RNA transport GO:0050658 50 50 1,000 1,41E-03 0,04329595 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! RNA localization GO:0006403 52 52 1,000 1,524E-03 0,04604368 ! regulation of GTPase activity GO:0043087 53 52 1,000 1,524E-03 0,04530104 ! response to light stimulus GO:0009416 53 52 1,000 1,524E-03 0,04458197 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 1,583E-03 0,0455798 ! regulation of cell adhesion GO:0030155 56 55 1,000 1,704E-03 0,048307 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 2,025E-03 0,05654063 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 2,092E-03 0,0575512 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 2,161E-03 0,05856088 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 2,301E-03 0,06145539 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 2,372E-03 0,06246413 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 2,445E-03 0,06347184 ! response to radiation GO:0009314 70 68 1,000 2,594E-03 0,06639371 ! regulation of cell size GO:0008361 68 68 1,000 2,594E-03 0,06548421 ! regulation of translation GO:0006417 69 69 1,000 2,67E-03 0,06648884 ! ribosome biogenesis GO:0042254 71 71 1,000 2,825E-03 0,06940825 ! negative regulation of signal transduction GO:0009968 71 71 1,000 2,825E-03 0,06849498 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 2,904E-03 0,06949648 ! negative regulation of cell communication GO:0010648 76 76 1,000 3,23E-03 0,0763185 ! regulation of protein modification process GO:0031399 79 78 1,000 3,399E-03 0,07930511 ! nuclear transport GO:0051169 79 79 1,000 3,486E-03 0,08030107 GO:0006913|nucleocytoplasmic transport, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 4,502E-03 0,10243538 ! negative regulation of cell cycle GO:0045786 92 91 1,000 4,601E-03 0,10339965 ! DNA replication GO:0006260 91 91 1,000 4,601E-03 0,10215387 ! epidermis development GO:0008544 94 94 1,000 4,902E-03 0,10755243 ! regulation of cell growth GO:0001558 97 96 1,000 5,108E-03 0,11075355 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 5,318E-03 0,11396569 ! anti-apoptosis GO:0006916 100 99 1,000 5,424E-03 0,11491145 ! ectoderm development GO:0007398 99 99 1,000 5,424E-03 0,11360564 ! response to hormone stimulus GO:0009725 102 100 1,000 5,532E-03 0,11455471 ! rRNA transcription GO:0009303 5 5 0,000 5,802E-03 0,11881476 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 5,802E-03 0,1175091 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 5,802E-03 0,11623183 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 5,802E-03 0,11498202 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 5,802E-03 0,11375881 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 5,802E-03 0,11256135 ! reproductive cellular process GO:0048610 5 5 0,000 5,802E-03 0,11138883 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 5,802E-03 0,1102405 ! negative regulation of blood pressure GO:0045776 6 5 0,000 5,802E-03 0,10911559 ! prostate gland development GO:0030850 5 5 0,000 5,802E-03 0,10801342 ! metencephalon development GO:0022037 5 5 0,000 5,802E-03 0,10693328 ! water transport GO:0006833 5 5 0,000 5,802E-03 0,10587454 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 5,802E-03 0,10483655 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 5,802E-03 0,10381872 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 5,802E-03 0,10282046 ! glycerol metabolic process GO:0006071 5 5 0,000 5,802E-03 0,10184122 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 5,802E-03 0,10088045 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 5,802E-03 0,09993765 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 5,802E-03 0,0990123 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 5,802E-03 0,09810393 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 5,802E-03 0,09721207 ! filopodium assembly GO:0046847 7 5 0,000 5,802E-03 0,09633629 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 5,802E-03 0,09547614 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 5,802E-03 0,09463122 ! GTP metabolic process GO:0046039 5 5 0,000 5,802E-03 0,09380112 ! establishment of tissue polarity GO:0007164 5 5 0,000 5,802E-03 0,09298546 ! mRNA stabilization GO:0048255 5 5 0,000 5,802E-03 0,09218386 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 5,802E-03 0,09139597 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 5,802E-03 0,09062142 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 5,802E-03 0,0898599 ! social behavior GO:0035176 5 5 0,000 5,802E-03 0,08911107 ! macrophage chemotaxis GO:0048246 6 5 0,000 5,802E-03 0,08837461 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 5,802E-03 0,08765023 ! memory GO:0007613 5 5 0,000 5,802E-03 0,08693763 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 5,802E-03 0,08623652 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 5,802E-03 0,08554662 ! membrane hyperpolarization GO:0060081 5 5 0,000 5,802E-03 0,08486768 ! response to lipid GO:0033993 5 5 0,000 5,802E-03 0,08419943 ! erythrocyte maturation GO:0043249 5 5 0,000 5,802E-03 0,08354163 ! hippocampus development GO:0021766 6 5 0,000 5,802E-03 0,08289402 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 5,802E-03 0,08225637 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 5,802E-03 0,08162846 ! middle ear morphogenesis GO:0042474 5 5 0,000 5,802E-03 0,08101006 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 5,802E-03 0,08040096 ! mechanosensory behavior GO:0007638 5 5 0,000 5,802E-03 0,07980096 ! heart looping GO:0001947 5 5 0,000 5,802E-03 0,07920984 ! negative regulation of endocytosis GO:0045806 5 5 0,000 5,802E-03 0,07862741 ! response to interferon-gamma GO:0034341 5 5 0,000 5,802E-03 0,07805349 ! pseudouridine synthesis GO:0001522 5 5 0,000 5,802E-03 0,07748788 ! endocrine pancreas development GO:0031018 5 5 0,000 5,802E-03 0,07693042 ! pH reduction GO:0045851 5 5 0,000 5,802E-03 0,07638092 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 5,802E-03 0,07583921 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 5,802E-03 0,07530513 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 5,802E-03 0,07477852 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 5,802E-03 0,07425922 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 5,802E-03 0,07374709 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 5,802E-03 0,07324197 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 5,802E-03 0,07274373 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 5,802E-03 0,07225222 ! adrenal gland development GO:0030325 5 5 0,000 5,802E-03 0,0717673 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 5,802E-03 0,07128885 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 5,802E-03 0,07081674 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 5,802E-03 0,07035084 ! astrocyte differentiation GO:0048708 5 5 0,000 5,802E-03 0,06989103 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 5,802E-03 0,0694372 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 5,802E-03 0,06898921 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 5,802E-03 0,06854698 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 5,802E-03 0,06811037 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 5,802E-03 0,06767929 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 5,802E-03 0,06725364 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 5,802E-03 0,0668333 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 5,802E-03 0,06641819 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 5,802E-03 0,0660082 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 5,802E-03 0,06560324 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 5,802E-03 0,06520322 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 5,802E-03 0,06480805 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 5,802E-03 0,06441764 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 5,802E-03 0,0640319 ! response to ATP GO:0033198 5 5 0,000 5,802E-03 0,06365076 ! regulation of type I interferon production GO:0032479 5 5 0,000 5,802E-03 0,06327413 ! regulation of appetite GO:0032098 5 5 0,000 5,802E-03 0,06290193 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 5,802E-03 0,06253408 ! paraxial mesoderm development GO:0048339 5 5 0,000 5,802E-03 0,06217051 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 5,802E-03 0,06181115 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 5,802E-03 0,06145591 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 5,802E-03 0,06110473 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,802E-03 0,06075755 ! receptor clustering GO:0043113 5 5 0,000 5,802E-03 0,06041428 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 5,802E-03 0,06007488 ! fear response GO:0042596 5 5 0,000 5,802E-03 0,05973926 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 5,802E-03 0,05940738 ! lens development in camera-type eye GO:0002088 5 5 0,000 5,802E-03 0,05907916 ! retinol metabolic process GO:0042572 5 5 0,000 5,802E-03 0,05875455 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 5,802E-03 0,05843349 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 5,802E-03 0,05811591 ! positive regulation of exocytosis GO:0045921 6 5 0,000 5,802E-03 0,05780177 ! parturition GO:0007567 5 5 0,000 5,802E-03 0,05749101 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,802E-03 0,05718357 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 5,802E-03 0,0568794 ! Schwann cell differentiation GO:0014037 5 5 0,000 5,802E-03 0,05657846 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 5,802E-03 0,05628067 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 5,802E-03 0,05598601 ! protein heterooligomerization GO:0051291 5 5 0,000 5,802E-03 0,05569442 ! regulation of gliogenesis GO:0014013 5 5 0,000 5,802E-03 0,05540585 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 5,802E-03 0,05512025 ! response to UV-B GO:0010224 5 5 0,000 5,802E-03 0,05483758 ! oligodendrocyte development GO:0014003 5 5 0,000 5,802E-03 0,0545578 ! hyaluronan metabolic process GO:0030212 5 5 0,000 5,802E-03 0,05428085 ! activated T cell proliferation GO:0050798 5 5 0,000 5,802E-03 0,05400671 ! interaction with symbiont GO:0051702 5 5 0,000 5,802E-03 0,05373532 ! cellular extravasation GO:0045123 5 5 0,000 5,802E-03 0,05346664 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 5,802E-03 0,05320064 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 5,802E-03 0,05293727 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 5,802E-03 0,05267649 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 5,802E-03 0,05241828 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 5,802E-03 0,05216258 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 5,802E-03 0,05190936 ! response to amine stimulus GO:0014075 5 5 0,000 5,802E-03 0,05165859 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 5,802E-03 0,05141023 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 5,802E-03 0,05116425 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 5,802E-03 0,05092061 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 5,802E-03 0,05067928 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 5,802E-03 0,05044023 ! neuron recognition GO:0008038 5 5 0,000 5,802E-03 0,05020342 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 5,802E-03 0,04996882 ! decidualization GO:0046697 5 5 0,000 5,802E-03 0,04973641 ! hair follicle maturation GO:0048820 5 5 0,000 5,802E-03 0,04950615 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 5,802E-03 0,04927801 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 5,802E-03 0,04905196 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,802E-03 0,04882798 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 5,802E-03 0,04860604 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 5,802E-03 0,0483861 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 5,802E-03 0,04816814 ! postreplication repair GO:0006301 5 5 0,000 5,802E-03 0,04795214 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 5,802E-03 0,04773807 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 5,802E-03 0,0475259 ! histone methylation GO:0016571 5 5 0,000 5,802E-03 0,04731561 ! DNA methylation GO:0006306 5 5 0,000 5,802E-03 0,04710717 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 5,802E-03 0,04690056 ! T cell lineage commitment GO:0002360 5 5 0,000 5,802E-03 0,04669576 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 5,802E-03 0,04649273 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 5,802E-03 0,04629146 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 5,802E-03 0,04609193 ! intracellular cholesterol transport GO:0032367 5 5 0,000 5,802E-03 0,04589411 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 5,802E-03 0,04569798 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 5,802E-03 0,04550352 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 5,802E-03 0,04531071 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 5,802E-03 0,04511953 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 5,802E-03 0,04492995 ! sterol catabolic process GO:0016127 5 5 0,000 5,802E-03 0,04474196 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 5,802E-03 0,04455553 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 5,802E-03 0,04437066 ! detection of biotic stimulus GO:0009595 5 5 0,000 5,802E-03 0,04418731 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 5,802E-03 0,04400547 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 5,802E-03 0,04382512 ! zymogen activation GO:0031638 5 5 0,000 5,802E-03 0,04364624 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 5,802E-03 0,04346881 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 5,802E-03 0,04329283 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 5,802E-03 0,04311826 ! peptidyl-lysine modification GO:0018205 5 5 0,000 5,802E-03 0,04294509 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 5,802E-03 0,04277331 ! peptidyl-histidine modification GO:0018202 5 5 0,000 5,802E-03 0,0426029 ! nucleosome positioning GO:0016584 5 5 0,000 5,802E-03 0,04243384 ! regulation of isotype switching GO:0045191 5 5 0,000 5,802E-03 0,04226612 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 5,802E-03 0,04209972 ! negative regulation of neurological system process GO:0031645 5 5 0,000 5,802E-03 0,04193462 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 5,802E-03 0,04177081 ! glutathione biosynthetic process GO:0006750 5 5 0,000 5,802E-03 0,04160828 ! NADPH regeneration GO:0006740 5 5 0,000 5,802E-03 0,04144701 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 5,802E-03 0,04128698 ! positive regulation of epidermis development GO:0045684 5 5 0,000 5,802E-03 0,04112819 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 5,802E-03 0,04097061 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 5,802E-03 0,04081423 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 5,802E-03 0,04065904 ! sarcomere organization GO:0045214 5 5 0,000 5,802E-03 0,04050503 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 5,802E-03 0,04035218 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 5,802E-03 0,04020048 ! negative regulation of glucose transport GO:0010829 5 5 0,000 5,802E-03 0,04004992 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 5,802E-03 0,03990048 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 5,802E-03 0,03975215 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 5,802E-03 0,03960492 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 5,802E-03 0,03945878 ! spleen development GO:0048536 5 5 0,000 5,802E-03 0,03931371 ! male genitalia development GO:0030539 5 5 0,000 5,802E-03 0,0391697 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 5,802E-03 0,03902674 ! quaternary ammonium group transport GO:0015697 5 5 0,000 5,802E-03 0,03888483 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 5,802E-03 0,03874394 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 5,802E-03 0,03860407 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 5,802E-03 0,03846521 ! removal of superoxide radicals GO:0019430 6 5 0,000 5,802E-03 0,03832734 ! myeloid cell homeostasis GO:0002262 5 5 0,000 5,802E-03 0,03819046 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 5,802E-03 0,03805455 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 5,802E-03 0,0379196 ! ATP catabolic process GO:0006200 5 5 0,000 5,802E-03 0,03778561 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 5,802E-03 0,03765256 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 5,802E-03 0,03752045 ! blastocyst formation GO:0001825 5 5 0,000 5,802E-03 0,03738926 ! regulation of fibrinolysis GO:0051917 5 5 0,000 5,802E-03 0,03725898 ! embryonic gut development GO:0048566 5 5 0,000 5,802E-03 0,03712961 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 5,802E-03 0,03700114 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 5,802E-03 0,03687355 ! activation of innate immune response GO:0002218 5 5 0,000 5,802E-03 0,03674683 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 5,802E-03 0,03662099 ! catecholamine transport GO:0051937 5 5 0,000 5,802E-03 0,036496 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 5,802E-03 0,03637186 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 5,802E-03 0,03624857 ! muscle adaptation GO:0043500 5 5 0,000 5,802E-03 0,03612611 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 5,802E-03 0,03600447 ! embryonic heart tube development GO:0035050 5 5 0,000 5,802E-03 0,03588365 ! cardiac cell differentiation GO:0035051 6 5 0,000 5,802E-03 0,03576364 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 5,802E-03 0,03564443 ! defense response to fungus GO:0050832 5 5 0,000 5,802E-03 0,03552601 ! lysogeny GO:0030069 5 5 0,000 5,802E-03 0,03540837 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 5,802E-03 0,03529151 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 5,802E-03 0,03517542 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 5,802E-03 0,03506009 ! response to nicotine GO:0035094 5 5 0,000 5,802E-03 0,03494552 ! establishment of cell polarity GO:0030010 5 5 0,000 5,802E-03 0,03483169 ! mitochondrion localization GO:0051646 5 5 0,000 5,802E-03 0,0347186 ! nucleus localization GO:0051647 5 5 0,000 5,802E-03 0,03460624 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 5,802E-03 0,03449461 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 6,959E-03 0,04123944 ! axon extension GO:0048675 7 6 0,000 6,959E-03 0,04110727 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 6,959E-03 0,04097593 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 6,959E-03 0,04084544 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 6,959E-03 0,04071577 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 6,959E-03 0,04058692 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 6,959E-03 0,04045889 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 6,959E-03 0,04033166 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 6,959E-03 0,04020523 ! virus-host interaction GO:0019048 6 6 0,000 6,959E-03 0,04007958 ! regulation of S phase GO:0033261 6 6 0,000 6,959E-03 0,03995473 ! myotube differentiation GO:0014902 6 6 0,000 6,959E-03 0,03983064 ! regulation of B cell proliferation GO:0030888 6 6 0,000 6,959E-03 0,03970733 ! bone remodeling GO:0046849 6 6 0,000 6,959E-03 0,03958477 ! N-glycan processing GO:0006491 6 6 0,000 6,959E-03 0,03946297 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,959E-03 0,03934192 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 6,959E-03 0,03922161 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 6,959E-03 0,03910203 ! retina development in camera-type eye GO:0060041 6 6 0,000 6,959E-03 0,03898318 ! RNA methylation GO:0001510 6 6 0,000 6,959E-03 0,03886505 ! cartilage condensation GO:0001502 7 6 0,000 6,959E-03 0,03874763 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 6,959E-03 0,03863092 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 6,959E-03 0,03851492 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 6,959E-03 0,0383996 ! artery development GO:0060840 6 6 0,000 6,959E-03 0,03828498 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 6,959E-03 0,03817103 ! bile acid metabolic process GO:0008206 6 6 0,000 6,959E-03 0,03805776 ! androgen metabolic process GO:0008209 6 6 0,000 6,959E-03 0,03794517 ! estrogen metabolic process GO:0008210 6 6 0,000 6,959E-03 0,03783324 ! limbic system development GO:0021761 7 6 0,000 6,959E-03 0,03772196 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 6,959E-03 0,03761134 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 6,959E-03 0,03750136 ! positive regulation of heart contraction GO:0045823 6 6 0,000 6,959E-03 0,03739203 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 6,959E-03 0,03728333 ! pathogenesis GO:0009405 6 6 0,000 6,959E-03 0,03717527 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 6,959E-03 0,03706782 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 6,959E-03 0,036961 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 6,959E-03 0,03685479 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 6,959E-03 0,03674919 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 6,959E-03 0,03664419 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 6,959E-03 0,03653979 ! arginine metabolic process GO:0006525 6 6 0,000 6,959E-03 0,03643599 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 6,959E-03 0,03633277 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 6,959E-03 0,03623013 ! glutamate catabolic process GO:0006538 7 6 0,000 6,959E-03 0,03612808 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 6,959E-03 0,03602659 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 6,959E-03 0,03592568 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 6,959E-03 0,03582533 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 6,959E-03 0,03572553 ! ER overload response GO:0006983 6 6 0,000 6,959E-03 0,0356263 ! V(D)J recombination GO:0033151 6 6 0,000 6,959E-03 0,03552761 ! focal adhesion formation GO:0048041 7 6 0,000 6,959E-03 0,03542947 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,959E-03 0,03533186 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 6,959E-03 0,0352348 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 6,959E-03 0,03513827 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 6,959E-03 0,03504226 ! regulation of heart rate GO:0002027 6 6 0,000 6,959E-03 0,03494678 ! lipid digestion GO:0044241 6 6 0,000 6,959E-03 0,03485181 ! asymmetric protein localization GO:0008105 6 6 0,000 6,959E-03 0,03475736 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 6,959E-03 0,03466342 ! phagocytosis, engulfment GO:0006911 6 6 0,000 6,959E-03 0,03456999 ! Rac protein signal transduction GO:0016601 6 6 0,000 6,959E-03 0,03447706 ! regulation of vascular permeability GO:0043114 6 6 0,000 6,959E-03 0,03438463 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 6,959E-03 0,03429269 ! ruffle organization GO:0031529 6 6 0,000 6,959E-03 0,03420124 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 6,959E-03 0,03411028 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 6,959E-03 0,03401981 ! retinoic acid metabolic process GO:0042573 6 6 0,000 6,959E-03 0,03392981 ! neutral amino acid transport GO:0015804 6 6 0,000 6,959E-03 0,03384028 ! L-amino acid transport GO:0015807 6 6 0,000 6,959E-03 0,03375123 ! bone mineralization GO:0030282 6 6 0,000 6,959E-03 0,03366264 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 6,959E-03 0,03357452 ! negative regulation of ossification GO:0030279 6 6 0,000 6,959E-03 0,03348686 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 6,959E-03 0,03339965 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 6,959E-03 0,0333129 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 6,959E-03 0,0332266 ! purine base biosynthetic process GO:0009113 6 6 0,000 6,959E-03 0,03314074 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 6,959E-03 0,03305533 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 6,959E-03 0,03297035 ! regulation of phagocytosis GO:0050764 6 6 0,000 6,959E-03 0,03288581 ! regulation of organ growth GO:0046620 6 6 0,000 6,959E-03 0,03280171 ! regulation of circadian rhythm GO:0042752 6 6 0,000 6,959E-03 0,03271803 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 6,959E-03 0,03263478 ! response to dsRNA GO:0043331 6 6 0,000 6,959E-03 0,03255195 ! DNA unwinding during replication GO:0006268 6 6 0,000 6,959E-03 0,03246954 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 6,959E-03 0,03238754 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 6,959E-03 0,03230596 ! genitalia development GO:0048806 6 6 0,000 6,959E-03 0,03222479 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 6,959E-03 0,03214403 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 6,959E-03 0,03206367 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 6,959E-03 0,03198371 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 6,959E-03 0,03190415 ! multicellular organismal aging GO:0010259 6 6 0,000 6,959E-03 0,03182498 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 6,959E-03 0,0317462 ! erythrocyte development GO:0048821 6 6 0,000 6,959E-03 0,03166782 ! renal water homeostasis GO:0003091 6 6 0,000 6,959E-03 0,03158982 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 6,959E-03 0,0315122 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 6,959E-03 0,03143497 ! ribosome assembly GO:0042255 6 6 0,000 6,959E-03 0,03135811 ! diencephalon development GO:0021536 6 6 0,000 6,959E-03 0,03128163 ! fucose catabolic process GO:0019317 6 6 0,000 6,959E-03 0,03120552 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 6,959E-03 0,03112977 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 6,959E-03 0,0310544 ! regulation of lipid transport GO:0032368 6 6 0,000 6,959E-03 0,03097939 ! regulation of cell division GO:0051302 6 6 0,000 6,959E-03 0,03090474 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 6,959E-03 0,03083045 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 6,959E-03 0,03075652 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 6,959E-03 0,03068293 ! salivary gland morphogenesis GO:0007435 6 6 0,000 6,959E-03 0,03060971 ! neuroblast proliferation GO:0007405 6 6 0,000 6,959E-03 0,03053683 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 6,959E-03 0,03046429 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 6,959E-03 0,0303921 ! regulation of glucose transport GO:0010827 6 6 0,000 6,959E-03 0,03032025 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 6,959E-03 0,03024874 ! methionine biosynthetic process GO:0009086 6 6 0,000 6,959E-03 0,03017757 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 6,959E-03 0,03010673 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 6,959E-03 0,03003622 ! thymus development GO:0048538 6 6 0,000 6,959E-03 0,02996604 ! lymph node development GO:0048535 6 6 0,000 6,959E-03 0,02989619 ! organic cation transport GO:0015695 6 6 0,000 6,959E-03 0,02982667 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 6,959E-03 0,02975746 ! regulation of RNA splicing GO:0043484 6 6 0,000 6,959E-03 0,02968858 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 6,959E-03 0,02962002 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 6,959E-03 0,02955177 ! sperm-egg recognition GO:0035036 7 6 0,000 6,959E-03 0,02948383 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 6,959E-03 0,02941621 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 6,959E-03 0,02934889 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 6,959E-03 0,02928189 ! alditol metabolic process GO:0019400 6 6 0,000 6,959E-03 0,02921519 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 6,959E-03 0,02914879 ! regulation of amino acid transport GO:0051955 6 6 0,000 6,959E-03 0,02908269 ! maternal placenta development GO:0001893 6 6 0,000 6,959E-03 0,02901689 ! regulation of embryonic development GO:0045995 6 6 0,000 6,959E-03 0,02895139 ! negative regulation of immune effector process GO:0002698 6 6 0,000 6,959E-03 0,02888619 ! localization within membrane GO:0051668 6 6 0,000 6,959E-03 0,02882127 ! respiratory burst GO:0045730 7 7 0,000 8,115E-03 0,03353236 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 8,115E-03 0,03345735 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 8,115E-03 0,03338267 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 8,115E-03 0,03330832 ! positive regulation of blood pressure GO:0045777 7 7 0,000 8,115E-03 0,0332343 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 8,115E-03 0,03316061 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 8,115E-03 0,03308724 ! regulation of chemokine production GO:0032642 7 7 0,000 8,115E-03 0,0330142 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 8,115E-03 0,03294149 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 8,115E-03 0,03286909 ! cellular protein complex disassembly GO:0043624 8 7 0,000 8,115E-03 0,032797 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 8,115E-03 0,03272524 ! gene silencing by RNA GO:0031047 7 7 0,000 8,115E-03 0,03265379 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 8,115E-03 0,03258265 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 8,115E-03 0,03251181 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 8,115E-03 0,03244129 ! axis specification GO:0009798 7 7 0,000 8,115E-03 0,03237107 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 8,115E-03 0,03230115 ! visual behavior GO:0007632 7 7 0,000 8,115E-03 0,03223154 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 8,115E-03 0,03216222 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 8,115E-03 0,03209321 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 8,115E-03 0,03202448 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 8,115E-03 0,03195606 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 8,115E-03 0,03188792 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 8,115E-03 0,03182007 ! endothelial cell differentiation GO:0045446 7 7 0,000 8,115E-03 0,03175251 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 8,115E-03 0,03168524 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 8,115E-03 0,03161825 ! digestive system development GO:0055123 7 7 0,000 8,115E-03 0,03155155 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 8,115E-03 0,03148512 ! regulation of exit from mitosis GO:0007096 7 7 0,000 8,115E-03 0,03141898 ! protein targeting to ER GO:0045047 8 7 0,000 8,115E-03 0,03135311 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 8,115E-03 0,03128752 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 8,115E-03 0,0312222 ! endoderm development GO:0007492 7 7 0,000 8,115E-03 0,03115715 ! regulation of defense response to virus GO:0050688 7 7 0,000 8,115E-03 0,03109238 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 8,115E-03 0,03102787 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 8,115E-03 0,03096363 ! response to hexose stimulus GO:0009746 7 7 0,000 8,115E-03 0,03089966 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 8,115E-03 0,03083595 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 8,115E-03 0,0307725 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 8,115E-03 0,03070931 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 8,115E-03 0,03064638 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 8,115E-03 0,03058371 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 8,115E-03 0,03052129 ! complement activation, alternative pathway GO:0006957 7 7 0,000 8,115E-03 0,03045913 ! arachidonic acid secretion GO:0050482 7 7 0,000 8,115E-03 0,03039722 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 8,115E-03 0,03033557 ! response to X-ray GO:0010165 7 7 0,000 8,115E-03 0,03027416 ! regulation of intracellular pH GO:0051453 7 7 0,000 8,115E-03 0,030213 ! DNA integration GO:0015074 7 7 0,000 8,115E-03 0,03015209 ! myofibril assembly GO:0030239 7 7 0,000 8,115E-03 0,03009142 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 8,115E-03 0,03003099 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 8,115E-03 0,02997081 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 8,115E-03 0,02991087 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 8,115E-03 0,02985117 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 8,115E-03 0,0297917 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 8,115E-03 0,02973247 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 8,115E-03 0,02967348 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 8,115E-03 0,02961472 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 8,115E-03 0,02955619 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 8,115E-03 0,0294979 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 8,115E-03 0,02943983 ! axon cargo transport GO:0008088 7 7 0,000 8,115E-03 0,02938199 ! eating behavior GO:0042755 7 7 0,000 8,115E-03 0,02932438 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 8,115E-03 0,02926699 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 8,115E-03 0,02920983 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 8,115E-03 0,02915289 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 8,115E-03 0,02909618 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 8,115E-03 0,02903968 ! cranial nerve development GO:0021545 7 7 0,000 8,115E-03 0,0289834 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 8,115E-03 0,02892734 ! induction of an organ GO:0001759 7 7 0,000 8,115E-03 0,02887149 ! leukocyte activation during immune response GO:0002366 7 7 0,000 8,115E-03 0,02881587 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 8,115E-03 0,02876045 ! autonomic nervous system development GO:0048483 7 7 0,000 8,115E-03 0,02870525 ! intracellular lipid transport GO:0032365 7 7 0,000 8,115E-03 0,02865026 ! detection of chemical stimulus GO:0009593 8 7 0,000 8,115E-03 0,02859548 ! platelet activation GO:0030168 8 7 0,000 8,115E-03 0,02854091 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 8,115E-03 0,02848654 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 8,115E-03 0,02843238 ! natural killer cell activation GO:0030101 7 7 0,000 8,115E-03 0,02837843 ! response to gamma radiation GO:0010332 8 7 0,000 8,115E-03 0,02832469 ! NADP metabolic process GO:0006739 7 7 0,000 8,115E-03 0,02827114 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 8,115E-03 0,0282178 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 8,115E-03 0,02816466 ! ubiquinone metabolic process GO:0006743 7 7 0,000 8,115E-03 0,02811172 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 8,115E-03 0,02805898 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 8,115E-03 0,02800643 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 8,115E-03 0,02795408 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 8,115E-03 0,02790193 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 8,115E-03 0,02784997 ! regulation of ATPase activity GO:0043462 7 7 0,000 8,115E-03 0,0277982 ! cell-cell recognition GO:0009988 8 7 0,000 8,115E-03 0,02774663 ! hormone catabolic process GO:0042447 7 7 0,000 8,115E-03 0,02769525 ! dopamine metabolic process GO:0042417 7 7 0,000 8,115E-03 0,02764406 ! cAMP biosynthetic process GO:0006171 7 7 0,000 8,115E-03 0,02759305 ! oxygen transport GO:0015671 7 7 0,000 8,115E-03 0,02754224 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 8,115E-03 0,02749161 ! regulation of mRNA stability GO:0043488 7 7 0,000 8,115E-03 0,02744116 ! biogenic amine catabolic process GO:0042402 7 7 0,000 8,115E-03 0,02739091 ! regulation of axon extension GO:0030516 7 7 0,000 8,115E-03 0,02734083 ! cell killing GO:0001906 7 7 0,000 8,115E-03 0,02729094 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 8,115E-03 0,02724123 ! adult feeding behavior GO:0008343 7 7 0,000 8,115E-03 0,0271917 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 8,115E-03 0,02714235 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 8,115E-03 0,02709318 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 8,115E-03 0,02704418 ! negative regulation of T cell activation GO:0050868 7 7 0,000 8,115E-03 0,02699537 ! response to cold GO:0009409 7 7 0,000 8,115E-03 0,02694673 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 9,269E-03 0,03072524 ! negative regulation of muscle development GO:0048635 8 8 0,000 9,269E-03 0,03067008 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 9,269E-03 0,03061511 ! positive regulation of translation GO:0045727 8 8 0,000 9,269E-03 0,03056034 ! positive regulation of cell killing GO:0031343 8 8 0,000 9,269E-03 0,03050577 ! superoxide anion generation GO:0042554 8 8 0,000 9,269E-03 0,03045139 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 9,269E-03 0,03039721 ! cGMP metabolic process GO:0046068 8 8 0,000 9,269E-03 0,03034322 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 9,269E-03 0,03028942 ! 'de novo' protein folding GO:0006458 8 8 0,000 9,269E-03 0,03023581 ! dicarboxylic acid transport GO:0006835 8 8 0,000 9,269E-03 0,03018239 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 9,269E-03 0,03012916 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 9,269E-03 0,03007611 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 9,269E-03 0,03002326 ! zinc ion transport GO:0006829 8 8 0,000 9,269E-03 0,02997058 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 9,269E-03 0,0299181 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 9,269E-03 0,02986579 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 9,269E-03 0,02981367 ! cardiac muscle contraction GO:0060048 8 8 0,000 9,269E-03 0,02976173 ! lipid localization GO:0010876 8 8 0,000 9,269E-03 0,02970997 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 9,269E-03 0,02965839 ! response to cAMP GO:0051591 8 8 0,000 9,269E-03 0,02960699 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 9,269E-03 0,02955577 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 9,269E-03 0,02950472 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 9,269E-03 0,02945385 ! negative regulation of ion transport GO:0043271 8 8 0,000 9,269E-03 0,02940315 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 9,269E-03 0,02935263 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 9,269E-03 0,02930229 ! sensory perception of taste GO:0050909 8 8 0,000 9,269E-03 0,02925211 ! organelle fusion GO:0048284 8 8 0,000 9,269E-03 0,02920211 ! pancreas development GO:0031016 8 8 0,000 9,269E-03 0,02915227 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 9,269E-03 0,02910261 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 9,269E-03 0,02905312 ! negative regulation of proteolysis GO:0045861 8 8 0,000 9,269E-03 0,02900379 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 9,269E-03 0,02895463 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 9,269E-03 0,02890564 ! sperm motility GO:0030317 8 8 0,000 9,269E-03 0,02885681 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 9,269E-03 0,02880815 ! DNA duplex unwinding GO:0032508 8 8 0,000 9,269E-03 0,02875965 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 9,269E-03 0,02871131 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 9,269E-03 0,02866314 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 9,269E-03 0,02861513 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 9,269E-03 0,02856728 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 9,269E-03 0,02851959 ! Golgi organization GO:0007030 8 8 0,000 9,269E-03 0,02847205 ! cell-cell junction assembly GO:0007043 8 8 0,000 9,269E-03 0,02842468 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 9,269E-03 0,02837746 ! fructose metabolic process GO:0006000 8 8 0,000 9,269E-03 0,0283304 ! mannose metabolic process GO:0006013 9 8 0,000 9,269E-03 0,0282835 ! NAD metabolic process GO:0019674 8 8 0,000 9,269E-03 0,02823675 ! sex determination GO:0007530 8 8 0,000 9,269E-03 0,02819015 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 9,269E-03 0,02814371 ! plasma membrane fusion GO:0045026 8 8 0,000 9,269E-03 0,02809742 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 9,269E-03 0,02805128 ! response to fungus GO:0009620 8 8 0,000 9,269E-03 0,0280053 ! stem cell differentiation GO:0048863 8 8 0,000 9,269E-03 0,02795946 ! alpha-beta T cell activation GO:0046631 8 8 0,000 9,269E-03 0,02791378 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 9,269E-03 0,02786824 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 9,269E-03 0,02782285 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 9,269E-03 0,02777761 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 9,269E-03 0,02773252 ! regulation of vasodilation GO:0042312 8 8 0,000 9,269E-03 0,02768757 ! vasoconstriction GO:0042310 8 8 0,000 9,269E-03 0,02764277 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 9,269E-03 0,02759811 ! muscle cell development GO:0055001 8 8 0,000 9,269E-03 0,0275536 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 9,269E-03 0,02750923 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 9,269E-03 0,027465 ! sensory perception of pain GO:0019233 8 8 0,000 9,269E-03 0,02742092 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 9,269E-03 0,02737697 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 9,269E-03 0,02733317 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 9,269E-03 0,02728951 ! chromatin silencing GO:0006342 8 8 0,000 9,269E-03 0,02724598 ! tissue regeneration GO:0042246 8 8 0,000 9,269E-03 0,0272026 ! salivary gland development GO:0007431 8 8 0,000 9,269E-03 0,02715935 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 9,269E-03 0,02711624 ! T cell homeostasis GO:0043029 8 8 0,000 9,269E-03 0,02707327 ! peptide biosynthetic process GO:0043043 9 8 0,000 9,269E-03 0,02703043 ! peptidyl-serine modification GO:0018209 8 8 0,000 9,269E-03 0,02698773 ! water homeostasis GO:0030104 8 8 0,000 9,269E-03 0,02694516 ! cofactor transport GO:0051181 8 8 0,000 9,269E-03 0,02690273 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 9,269E-03 0,02686043 ! acid secretion GO:0046717 8 8 0,000 9,269E-03 0,02681826 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 9,269E-03 0,02677623 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 9,269E-03 0,02673432 ! protein-chromophore linkage GO:0018298 9 8 0,000 9,269E-03 0,02669255 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 9,269E-03 0,02665091 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 9,269E-03 0,0266094 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 9,269E-03 0,02656801 ! regulation of RNA stability GO:0043487 8 8 0,000 9,269E-03 0,02652676 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 9,269E-03 0,02648563 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 9,269E-03 0,02644463 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 9,269E-03 0,02640376 ! regulation of organic acid transport GO:0032890 8 8 0,000 9,269E-03 0,02636301 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 9,269E-03 0,02632239 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 9,269E-03 0,0262819 ! regulation of multi-organism process GO:0043900 8 8 0,000 9,269E-03 0,02624152 ! positive regulation of amine transport GO:0051954 8 8 0,000 9,269E-03 0,02620128 ! developmental induction GO:0031128 8 8 0,000 9,269E-03 0,02616115 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 9,269E-03 0,02612115 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 9,269E-03 0,02608127 ! actin filament polymerization GO:0030041 9 8 0,000 9,269E-03 0,02604151 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 9,269E-03 0,02600188 ! peptide hormone processing GO:0016486 8 8 0,000 9,269E-03 0,02596236 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 9,269E-03 0,02592296 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 9,269E-03 0,02588369 ! lactation GO:0007595 10 9 0,000 0,01042261 0,02906031 ! embryonic pattern specification GO:0009880 10 9 0,000 0,01042261 0,02901641 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,01042261 0,02897264 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,01042261 0,02892901 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,01042261 0,02888551 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,01042261 0,02884214 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,01042261 0,0287989 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,01042261 0,02875578 ! viral genome replication GO:0019079 9 9 0,000 0,01042261 0,0287128 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,01042261 0,02866994 ! copper ion transport GO:0006825 9 9 0,000 0,01042261 0,02862722 ! lipid phosphorylation GO:0046834 9 9 0,000 0,01042261 0,02858462 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,01042261 0,02854214 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,01042261 0,0284998 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,01042261 0,02845757 ! RNA polyadenylation GO:0043631 9 9 0,000 0,01042261 0,02841548 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,01042261 0,02837351 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,01042261 0,02833166 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,01042261 0,02828993 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,01042261 0,02824833 ! phospholipid efflux GO:0033700 9 9 0,000 0,01042261 0,02820685 ! response to alkaloid GO:0043279 10 9 0,000 0,01042261 0,02816549 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,01042261 0,02812425 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,01042261 0,02808313 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,01042261 0,02804214 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,01042261 0,02800126 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,01042261 0,0279605 ! response to ethanol GO:0045471 9 9 0,000 0,01042261 0,02791986 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,01042261 0,02787934 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,01042261 0,02783893 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,01042261 0,02779864 ! methionine metabolic process GO:0006555 9 9 0,000 0,01042261 0,02775847 ! glutamine metabolic process GO:0006541 9 9 0,000 0,01042261 0,02771842 ! cerebral cortex development GO:0021987 9 9 0,000 0,01042261 0,02767848 ! response to osmotic stress GO:0006970 9 9 0,000 0,01042261 0,02763865 ! pigmentation during development GO:0048066 9 9 0,000 0,01042261 0,02759894 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,01042261 0,02755934 ! central nervous system neuron development GO:0021954 10 9 0,000 0,01042261 0,02751986 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,01042261 0,02748049 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,01042261 0,02744123 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,01042261 0,02740209 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,01042261 0,02736305 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,01042261 0,02732413 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,01042261 0,02728532 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,01042261 0,02724661 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,01042261 0,02720802 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,01042261 0,02716954 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,01042261 0,02713116 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,01042261 0,0270929 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,01042261 0,02705474 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,01042261 0,02701669 ! DNA replication initiation GO:0006270 9 9 0,000 0,01042261 0,02697874 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,01042261 0,0269409 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,01042261 0,02690317 ! regulation of cellular pH GO:0030641 9 9 0,000 0,01042261 0,02686554 ! histone acetylation GO:0016573 9 9 0,000 0,01042261 0,02682802 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,01042261 0,0267906 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,01042261 0,02675329 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,01042261 0,02671608 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,01042261 0,02667898 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,01042261 0,02664197 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,01042261 0,02660507 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,01042261 0,02656828 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,01042261 0,02653158 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,01042261 0,02649498 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,01042261 0,02645849 ! collagen catabolic process GO:0030574 9 9 0,000 0,01042261 0,02642209 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,01042261 0,0263858 ! purine base metabolic process GO:0006144 9 9 0,000 0,01042261 0,02634961 ! gas transport GO:0015669 9 9 0,000 0,01042261 0,02631351 ! cholesterol efflux GO:0033344 9 9 0,000 0,01042261 0,02627751 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,01042261 0,02624162 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,01042261 0,02620582 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,01042261 0,02617011 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,01042261 0,02613451 ! defense response to virus GO:0051607 9 9 0,000 0,01042261 0,026099 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,01042261 0,02606359 ! actin filament-based movement GO:0030048 9 9 0,000 0,01042261 0,02602827 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,01042261 0,02599305 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01157478 0,02882747 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01157478 0,02878857 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01157478 0,02874977 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,01157478 0,02871107 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01157478 0,02867248 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01157478 0,028634 ! neuron maturation GO:0042551 10 10 0,000 0,01157478 0,02859561 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01157478 0,02855733 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01157478 0,02851916 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01157478 0,02848108 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01157478 0,0284431 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01157478 0,02840523 ! hormone secretion GO:0046879 10 10 0,000 0,01157478 0,02836746 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01157478 0,02832979 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01157478 0,02829221 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,01157478 0,02825474 ! inositol metabolic process GO:0006020 10 10 0,000 0,01157478 0,02821737 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01157478 0,02818009 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01157478 0,02814291 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01157478 0,02810583 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01157478 0,02806885 ! glial cell development GO:0021782 10 10 0,000 0,01157478 0,02803197 ! phototransduction GO:0007602 11 10 0,000 0,01157478 0,02799518 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01157478 0,02795849 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01157478 0,0279219 ! fat cell differentiation GO:0045444 10 10 0,000 0,01157478 0,0278854 ! myoblast differentiation GO:0045445 10 10 0,000 0,01157478 0,02784899 ! centrosome cycle GO:0007098 10 10 0,000 0,01157478 0,02781268 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01157478 0,02777647 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01157478 0,02774035 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01157478 0,02770432 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01157478 0,02766839 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01157478 0,02763255 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,01157478 0,0275968 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01157478 0,02756115 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01157478 0,02752558 ! plasma membrane organization GO:0007009 10 10 0,000 0,01157478 0,02749011 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01157478 0,02745473 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01157478 0,02741945 ! lysosomal transport GO:0007041 10 10 0,000 0,01157478 0,02738425 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01157478 0,02734914 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01157478 0,02731412 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,01157478 0,02727919 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,01157478 0,02724435 ! exocrine system development GO:0035272 10 10 0,000 0,01157478 0,0272096 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01157478 0,02717494 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01157478 0,02714037 ! embryo implantation GO:0007566 11 10 0,000 0,01157478 0,02710588 ! regulation of protein binding GO:0043393 11 10 0,000 0,01157478 0,02707148 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01157478 0,02703717 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01157478 0,02700295 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,01157478 0,02696881 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01157478 0,02693476 ! protein export from nucleus GO:0006611 10 10 0,000 0,01157478 0,02690079 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01157478 0,02686691 ! cytolysis GO:0019835 10 10 0,000 0,01157478 0,02683312 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01157478 0,02679941 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01157478 0,02676578 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01157478 0,02673224 ! histone deacetylation GO:0016575 10 10 0,000 0,01157478 0,02669878 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01157478 0,02666541 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01157478 0,02663212 ! gland morphogenesis GO:0022612 10 10 0,000 0,01157478 0,02659891 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01157478 0,02656579 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01157478 0,02653275 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01157478 0,02649979 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01157478 0,02646691 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,01157478 0,02643411 ! regulation of epidermis development GO:0045682 10 10 0,000 0,01157478 0,0264014 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01157478 0,02636876 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,01157478 0,02633621 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01157478 0,02630373 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01157478 0,02627134 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01157478 0,02623903 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01157478 0,02620679 ! nerve development GO:0021675 10 10 0,000 0,01157478 0,02617464 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,01157478 0,02614256 ! gut development GO:0048565 10 10 0,000 0,01157478 0,02611056 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01157478 0,02607864 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,01157478 0,0260468 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01157478 0,02601503 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01157478 0,02598335 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01157478 0,02595174 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01157478 0,0259202 ! protein stabilization GO:0050821 10 10 0,000 0,01157478 0,02588875 ! protein secretion GO:0009306 11 11 0,000 0,01272579 0,02842864 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01272579 0,02839422 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01272579 0,02835989 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01272579 0,02832564 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01272579 0,02829147 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01272579 0,02825739 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,01272579 0,02822338 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01272579 0,02818946 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01272579 0,02815562 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,01272579 0,02812186 ! signal complex assembly GO:0007172 11 11 0,000 0,01272579 0,02808818 ! microtubule-based transport GO:0010970 11 11 0,000 0,01272579 0,02805458 ! endothelial cell migration GO:0043542 11 11 0,000 0,01272579 0,02802106 ! peroxisomal transport GO:0043574 11 11 0,000 0,01272579 0,02798762 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01272579 0,02795427 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,01272579 0,02792099 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01272579 0,02788779 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01272579 0,02785467 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01272579 0,02782162 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01272579 0,02778866 ! T cell proliferation GO:0042098 11 11 0,000 0,01272579 0,02775577 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01272579 0,02772297 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01272579 0,02769024 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,01272579 0,02765758 ! spinal cord development GO:0021510 11 11 0,000 0,01272579 0,02762501 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01272579 0,02759251 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01272579 0,02756008 ! cellular response to starvation GO:0009267 11 11 0,000 0,01272579 0,02752773 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01272579 0,02749546 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,01272579 0,02746327 ! digestive system process GO:0022600 11 11 0,000 0,01272579 0,02743115 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01272579 0,0273991 ! fucose metabolic process GO:0006004 11 11 0,000 0,01272579 0,02736713 ! membrane budding GO:0006900 11 11 0,000 0,01272579 0,02733523 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,01272579 0,02730341 ! monoamine transport GO:0015844 11 11 0,000 0,01272579 0,02727166 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01272579 0,02723999 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01272579 0,02720839 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01272579 0,02717686 ! body fluid secretion GO:0007589 11 11 0,000 0,01272579 0,0271454 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01272579 0,02711402 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,01272579 0,02708271 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01272579 0,02705148 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01272579 0,02702031 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01272579 0,02698922 ! membrane depolarization GO:0051899 11 11 0,000 0,01272579 0,0269582 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01272579 0,02692724 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01272579 0,02689636 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,01272579 0,02686556 ! oogenesis GO:0048477 11 11 0,000 0,01272579 0,02683482 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01272579 0,02680415 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01272579 0,02677355 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,01272579 0,02674302 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,01272579 0,02671256 ! muscle maintenance GO:0046716 12 11 0,000 0,01272579 0,02668217 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01272579 0,02665185 ! hindbrain development GO:0030902 11 11 0,000 0,01272579 0,0266216 ! steroid catabolic process GO:0006706 11 11 0,000 0,01272579 0,02659142 ! endocrine process GO:0050886 11 11 0,000 0,01272579 0,0265613 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01272579 0,02653126 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01272579 0,02650128 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01272579 0,02647137 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,01272579 0,02644152 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01272579 0,02641175 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,01387562 0,02876577 ! translational initiation GO:0006413 12 12 0,000 0,01387562 0,02873345 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,01387562 0,0287012 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,01387562 0,02866902 ! initiation of viral infection GO:0019059 12 12 0,000 0,01387562 0,02863692 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,01387562 0,02860489 ! iron ion transport GO:0006826 13 12 0,000 0,01387562 0,02857293 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,01387562 0,02854104 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,01387562 0,02850922 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,01387562 0,02847747 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,01387562 0,02844579 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,01387562 0,02841419 ! collagen metabolic process GO:0032963 12 12 0,000 0,01387562 0,02838265 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,01387562 0,02835119 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,01387562 0,02831979 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,01387562 0,02828846 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,01387562 0,0282572 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,01387562 0,02822601 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,01387562 0,02819489 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,01387562 0,02816384 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,01387562 0,02813286 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,01387562 0,02810194 ! retinoid metabolic process GO:0001523 12 12 0,000 0,01387562 0,0280711 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,01387562 0,02804032 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,01387562 0,02800961 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,01387562 0,02797896 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,01387562 0,02794838 ! acute-phase response GO:0006953 12 12 0,000 0,01387562 0,02791787 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01387562 0,02788743 ! vacuolar transport GO:0007034 12 12 0,000 0,01387562 0,02785705 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,01387562 0,02782674 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,01387562 0,02779649 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,01387562 0,02776631 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,01387562 0,02773619 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,01387562 0,02770614 ! male gonad development GO:0008584 12 12 0,000 0,01387562 0,02767616 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,01387562 0,02764624 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,01387562 0,02761638 ! renal system process GO:0003014 12 12 0,000 0,01387562 0,02758659 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,01387562 0,02755686 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,01387562 0,0275272 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,01387562 0,0274976 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,01387562 0,02746807 ! pallium development GO:0021543 13 12 0,000 0,01387562 0,02743859 ! cell fate determination GO:0001709 12 12 0,000 0,01387562 0,02740918 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,01387562 0,02737984 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,01387562 0,02735056 ! somitogenesis GO:0001756 13 12 0,000 0,01387562 0,02732133 ! G1 phase GO:0051318 13 12 0,000 0,01387562 0,02729218 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,01387562 0,02726308 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,01387562 0,02723405 ! detection of light stimulus GO:0009583 13 12 0,000 0,01387562 0,02720507 ! synaptogenesis GO:0007416 12 12 0,000 0,01387562 0,02717616 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,01387562 0,02714731 ! hormone transport GO:0009914 12 12 0,000 0,01387562 0,02711853 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,01387562 0,0270898 ! heme biosynthetic process GO:0006783 12 12 0,000 0,01387562 0,02706113 ! spermatid differentiation GO:0048515 13 12 0,000 0,01387562 0,02703253 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,01387562 0,02700398 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,01387562 0,0269755 ! neural tube closure GO:0001843 13 12 0,000 0,01387562 0,02694707 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,01387562 0,0269187 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,01387562 0,0268904 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,01387562 0,02686215 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,01502428 0,02905535 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,01502428 0,02902489 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,01502428 0,0289945 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,01502428 0,02896417 ! phenol metabolic process GO:0018958 13 13 0,000 0,01502428 0,02893391 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,01502428 0,0289037 ! gluconeogenesis GO:0006094 13 13 0,000 0,01502428 0,02887357 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,01502428 0,02884349 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,01502428 0,02881347 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,01502428 0,02878352 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,01502428 0,02875363 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,01502428 0,02872381 ! regeneration GO:0031099 13 13 0,000 0,01502428 0,02869404 ! keratinization GO:0031424 13 13 0,000 0,01502428 0,02866434 ! post-embryonic development GO:0009791 14 13 0,000 0,01502428 0,02863469 ! patterning of blood vessels GO:0001569 13 13 0,000 0,01502428 0,02860511 ! vasculogenesis GO:0001570 13 13 0,000 0,01502428 0,02857559 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,01502428 0,02854613 ! regulation of innate immune response GO:0045088 13 13 0,000 0,01502428 0,02851673 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,01502428 0,0284874 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,01502428 0,02845812 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,01502428 0,0284289 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,01502428 0,02839974 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,01502428 0,02837064 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,01502428 0,02834161 ! autophagy GO:0006914 13 13 0,000 0,01502428 0,02831263 ! receptor metabolic process GO:0043112 14 13 0,000 0,01502428 0,02828371 ! actin filament bundle formation GO:0051017 13 13 0,000 0,01502428 0,02825485 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,01502428 0,02822604 ! ureteric bud development GO:0001657 13 13 0,000 0,01502428 0,0281973 ! cell aging GO:0007569 13 13 0,000 0,01502428 0,02816862 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,01502428 0,02813999 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,01502428 0,02811142 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,01502428 0,02808291 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,01502428 0,02805446 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,01502428 0,02802606 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,01502428 0,02799772 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,01502428 0,02796944 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,01502428 0,02794122 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,01502428 0,02791305 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,01502428 0,02788494 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,01502428 0,02785689 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,01502428 0,02782889 ! vasodilation GO:0042311 14 13 0,000 0,01502428 0,02780095 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,01502428 0,02777307 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,01502428 0,02774524 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,01502428 0,02771747 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,01502428 0,02768975 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,01502428 0,02766209 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,01502428 0,02763448 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,01502428 0,02760693 ! immunoglobulin production GO:0002377 13 13 0,000 0,01502428 0,02757943 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,01502428 0,02755199 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,01502428 0,0275246 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,01502428 0,02749727 ! cell-cell junction organization GO:0045216 13 13 0,000 0,01502428 0,02746999 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,01502428 0,02744276 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,01502428 0,02741559 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,01502428 0,02738848 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,01502428 0,02736141 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,01502428 0,0273344 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,01502428 0,02730745 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,01502428 0,02728054 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,01502428 0,02725369 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,01502428 0,02722689 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,01502428 0,02720015 ! blastocyst development GO:0001824 13 13 0,000 0,01502428 0,02717345 ! telomere organization GO:0032200 13 13 0,000 0,01502428 0,02714681 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,01502428 0,02712022 ! regulation of amine transport GO:0051952 13 13 0,000 0,01502428 0,02709369 ! tissue homeostasis GO:0001894 13 13 0,000 0,01502428 0,0270672 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,01502428 0,02704077 ! protein tetramerization GO:0051262 13 13 0,000 0,01502428 0,02701439 ! neuron fate commitment GO:0048663 14 14 0,000 0,01617177 0,02904929 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,01617177 0,029021 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,01617177 0,02899277 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,01617177 0,0289646 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,01617177 0,02893648 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,01617177 0,02890841 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,01617177 0,0288804 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,01617177 0,02885244 ! protein amino acid acylation GO:0043543 14 14 0,000 0,01617177 0,02882454 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,01617177 0,02879669 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,01617177 0,02876889 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,01617177 0,02874115 ! vesicle docking GO:0048278 14 14 0,000 0,01617177 0,02871346 ! superoxide metabolic process GO:0006801 15 14 0,000 0,01617177 0,02868582 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,01617177 0,02865824 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,01617177 0,02863071 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,01617177 0,02860324 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,01617177 0,02857581 ! hair cycle GO:0042633 14 14 0,000 0,01617177 0,02854844 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,01617177 0,02852112 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,01617177 0,02849385 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,01617177 0,02846664 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,01617177 0,02843948 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,01617177 0,02841237 ! lysosome organization GO:0007040 14 14 0,000 0,01617177 0,02838531 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,01617177 0,0283583 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,01617177 0,02833134 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,01617177 0,02830444 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,01617177 0,02827758 ! primary neural tube formation GO:0014020 15 14 0,000 0,01617177 0,02825078 ! peptide cross-linking GO:0018149 14 14 0,000 0,01617177 0,02822403 ! regulation of behavior GO:0050795 14 14 0,000 0,01617177 0,02819732 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,01617177 0,02817067 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,01617177 0,02814407 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,01617177 0,02811752 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,01617177 0,02809102 ! formation of primary germ layer GO:0001704 14 14 0,000 0,01617177 0,02806457 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,01617177 0,02803817 ! collagen fibril organization GO:0030199 14 14 0,000 0,01617177 0,02801182 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,01617177 0,02798551 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,01617177 0,02795926 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,01617177 0,02793306 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,01617177 0,0279069 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,01617177 0,0278808 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,01617177 0,02785474 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,01617177 0,02782873 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,01617177 0,02780277 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,01617177 0,02777686 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,01731809 0,0297181 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,01731809 0,02969045 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,01731809 0,02966286 ! positive regulation of ossification GO:0045778 15 15 0,000 0,01731809 0,02963532 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,01731809 0,02960783 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,01731809 0,02958039 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,01731809 0,029553 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,01731809 0,02952566 ! response to vitamin GO:0033273 15 15 0,000 0,01731809 0,02949837 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,01731809 0,02947113 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,01731809 0,02944395 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,01731809 0,02941681 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,01731809 0,02938972 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,01731809 0,02936268 ! ovarian follicle development GO:0001541 15 15 0,000 0,01731809 0,0293357 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,01731809 0,02930876 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,01731809 0,02928187 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,01731809 0,02925503 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,01731809 0,02922824 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,01731809 0,0292015 ! heme metabolic process GO:0042168 15 15 0,000 0,01731809 0,02917481 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,01731809 0,02914816 ! chromosome condensation GO:0030261 15 15 0,000 0,01731809 0,02912157 ! response to starvation GO:0042594 15 15 0,000 0,01731809 0,02909502 ! response to ionizing radiation GO:0010212 16 15 0,000 0,01731809 0,02906852 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,01731809 0,02904207 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,01731809 0,02901567 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,01731809 0,02898932 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,01731809 0,02896301 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,01731809 0,02893675 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,01731809 0,02891054 ! phospholipid transport GO:0015914 15 15 0,000 0,01731809 0,02888438 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,01731809 0,02885826 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,01731809 0,02883219 ! glutathione metabolic process GO:0006749 16 15 0,000 0,01731809 0,02880617 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,01731809 0,0287802 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,01731809 0,02875427 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,01731809 0,02872839 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,01731809 0,02870255 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,01731809 0,02867676 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,01731809 0,02865102 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,01731809 0,02862532 ! protein homooligomerization GO:0051260 15 15 0,000 0,01731809 0,02859967 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,01731809 0,02857407 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,01846324 0,03043627 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,01846324 0,03040907 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,01846324 0,03038192 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,01846324 0,03035482 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,01846324 0,03032776 ! learning GO:0007612 16 16 0,000 0,01846324 0,03030076 ! circadian rhythm GO:0007623 16 16 0,000 0,01846324 0,0302738 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,01846324 0,03024689 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,01846324 0,03022003 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,01846324 0,03019321 ! vacuole organization GO:0007033 16 16 0,000 0,01846324 0,03016644 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,01846324 0,03013972 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,01846324 0,03011305 ! vesicle targeting GO:0006903 17 16 0,000 0,01846324 0,03008643 ! segmentation GO:0035282 17 16 0,000 0,01846324 0,03005985 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,01846324 0,03003332 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,01846324 0,03000683 ! iron ion homeostasis GO:0055072 16 16 0,000 0,01846324 0,0299804 ! positive regulation of cell development GO:0010720 16 16 0,000 0,01846324 0,029954 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,01846324 0,02992766 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,01846324 0,02990136 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,01846324 0,02987511 ! cell fate specification GO:0001708 16 16 0,000 0,01846324 0,0298489 ! pentose metabolic process GO:0019321 16 16 0,000 0,01846324 0,02982274 ! fatty acid transport GO:0015908 16 16 0,000 0,01846324 0,02979663 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,01846324 0,02977056 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,01846324 0,02974454 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,01846324 0,02971856 ! cofactor catabolic process GO:0051187 16 16 0,000 0,01846324 0,02969263 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,01846324 0,02966674 ! polyol metabolic process GO:0019751 16 16 0,000 0,01846324 0,0296409 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,01846324 0,0296151 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,01846324 0,02958935 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,01846324 0,02956364 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,01846324 0,02953798 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,01846324 0,02951236 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,01846324 0,02948678 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,01846324 0,02946125 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,01846324 0,02943577 ! regulation of coagulation GO:0050818 17 16 0,000 0,01846324 0,02941033 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,01960722 0,03120562 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,01960722 0,0311787 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,01960722 0,03115182 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,01960722 0,03112499 ! myelination GO:0042552 17 17 0,000 0,01960722 0,0310982 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,01960722 0,03107146 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,01960722 0,03104477 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,01960722 0,03101812 ! leukocyte adhesion GO:0007159 17 17 0,000 0,01960722 0,03099152 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,01960722 0,03096496 ! sensory perception of smell GO:0007608 17 17 0,000 0,01960722 0,03093845 ! glucose transport GO:0015758 17 17 0,000 0,01960722 0,03091198 ! cell junction assembly GO:0034329 18 17 0,000 0,01960722 0,03088556 ! tissue remodeling GO:0048771 17 17 0,000 0,01960722 0,03085919 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,01960722 0,03083286 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,01960722 0,03080657 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,01960722 0,03078033 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,01960722 0,03075413 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,01960722 0,03072798 ! neural crest cell development GO:0014032 19 17 0,000 0,01960722 0,03070188 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,01960722 0,03067581 ! negative regulation of cell development GO:0010721 18 17 0,000 0,01960722 0,03064979 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,01960722 0,03062382 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,01960722 0,03059789 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,01960722 0,030572 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,01960722 0,03054616 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,01960722 0,03052036 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,01960722 0,03049461 ! pigmentation GO:0043473 17 17 0,000 0,01960722 0,03046889 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,01960722 0,03044322 ! adult locomotory behavior GO:0008344 17 17 0,000 0,01960722 0,0304176 ! embryonic organ development GO:0048568 17 17 0,000 0,01960722 0,03039202 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,01960722 0,03036648 ! liver development GO:0001889 17 17 0,000 0,01960722 0,03034098 ! gene silencing GO:0016458 17 17 0,000 0,01960722 0,03031553 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,02075004 0,03205559 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,02075004 0,03202874 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,02075004 0,03200194 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,02075004 0,03197518 ! meiosis I GO:0007127 18 18 0,000 0,02075004 0,03194847 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,02075004 0,0319218 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,02075004 0,03189518 ! membrane docking GO:0022406 18 18 0,000 0,02075004 0,0318686 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,02075004 0,03184206 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,02075004 0,03181557 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,02075004 0,03178912 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,02075004 0,03176272 ! hexose transport GO:0008645 18 18 0,000 0,02075004 0,03173636 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,02075004 0,03171005 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,02075004 0,03168378 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,02075004 0,03165755 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,02075004 0,03163136 ! ceramide metabolic process GO:0006672 18 18 0,000 0,02075004 0,03160522 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,02075004 0,03157912 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,02075004 0,03155307 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,02075004 0,03152705 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,02075004 0,03150108 ! B cell differentiation GO:0030183 18 18 0,000 0,02075004 0,03147516 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,02075004 0,03144927 ! ensheathment of neurons GO:0007272 18 18 0,000 0,02075004 0,03142343 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,02075004 0,03139763 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,02075004 0,03137188 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,02075004 0,03134616 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,02075004 0,03132049 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,02075004 0,03129486 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,02189169 0,03298968 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,02189169 0,03296273 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,02189169 0,03293582 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,02189169 0,03290895 ! glial cell differentiation GO:0010001 19 19 0,000 0,02189169 0,03288213 ! regulation of pH GO:0006885 19 19 0,000 0,02189169 0,03285536 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,02189169 0,03282862 ! feeding behavior GO:0007631 19 19 0,000 0,02189169 0,03280193 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,02189169 0,03277529 ! peroxisome organization GO:0007031 19 19 0,000 0,02189169 0,03274868 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,02189169 0,03272212 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,02189169 0,03269561 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,02189169 0,03266913 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,02189169 0,0326427 ! metanephros development GO:0001656 19 19 0,000 0,02189169 0,03261631 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,02189169 0,03258997 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,02189169 0,03256366 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,02189169 0,0325374 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,02189169 0,03251118 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,02189169 0,03248501 ! peripheral nervous system development GO:0007422 19 19 0,000 0,02189169 0,03245887 ! regulation of protein stability GO:0031647 19 19 0,000 0,02189169 0,03243278 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,02189169 0,03240673 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,02189169 0,03238072 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,02189169 0,03235475 ! eye morphogenesis GO:0048592 19 19 0,000 0,02189169 0,03232883 ! regulation of cell shape GO:0008360 21 19 0,000 0,02189169 0,03230294 ! placenta development GO:0001890 19 19 0,000 0,02189169 0,0322771 ! response to heat GO:0009408 19 19 0,000 0,02189169 0,0322513 ! vesicle localization GO:0051648 20 19 0,000 0,02189169 0,03222554 ! regulation of muscle development GO:0048634 21 20 0,000 0,02303217 0,03387733 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,02303217 0,03385031 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,02303217 0,03382334 ! negative regulation of binding GO:0051100 21 20 0,000 0,02303217 0,03379641 ! organic ether metabolic process GO:0018904 20 20 0,000 0,02303217 0,03376952 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,02303217 0,03374268 ! neural tube development GO:0021915 21 20 0,000 0,02303217 0,03371588 ! nucleus organization GO:0006997 20 20 0,000 0,02303217 0,03368912 ! phagocytosis GO:0006909 21 20 0,000 0,02303217 0,0336624 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,02303217 0,03363573 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,02303217 0,0336091 ! protein targeting to membrane GO:0006612 22 20 0,000 0,02303217 0,03358251 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,02303217 0,03355596 ! chromatin remodeling GO:0006338 20 20 0,000 0,02303217 0,03352946 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,02303217 0,03350299 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,02303217 0,03347657 ! lipid oxidation GO:0034440 20 20 0,000 0,02303217 0,03345019 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,02303217 0,03342385 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,02303217 0,03339755 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,02303217 0,0333713 ! RNA modification GO:0009451 20 20 0,000 0,02303217 0,03334508 ! single fertilization GO:0007338 21 20 0,000 0,02303217 0,03331891 ! regulation of B cell activation GO:0050864 20 20 0,000 0,02303217 0,03329278 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,02417149 0,03491227 ! mRNA catabolic process GO:0006402 21 21 0,000 0,02417149 0,03488493 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,02417149 0,03485764 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,02417149 0,03483038 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,02417149 0,03480317 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,02417149 0,034776 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,02417149 0,03474888 ! Notch signaling pathway GO:0007219 22 21 0,000 0,02417149 0,03472179 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,02417149 0,03469475 ! ear morphogenesis GO:0042471 21 21 0,000 0,02417149 0,03466775 ! organic anion transport GO:0015711 21 21 0,000 0,02417149 0,03464079 ! cholesterol transport GO:0030301 21 21 0,000 0,02417149 0,03461388 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,02417149 0,034587 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,02417149 0,03456017 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,02417149 0,03453338 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,02417149 0,03450663 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,02417149 0,03447992 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,02417149 0,03445326 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,02417149 0,03442663 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,02417149 0,03440005 ! regulation of proteolysis GO:0030162 21 21 0,000 0,02417149 0,0343735 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,02417149 0,034347 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,02417149 0,03432054 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,02417149 0,03429412 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,02530965 0,0358813 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,02530965 0,03585372 ! sister chromatid segregation GO:0000819 22 22 0,000 0,02530965 0,03582618 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,02530965 0,03579868 ! regulation of ion transport GO:0043269 22 22 0,000 0,02530965 0,03577123 ! odontogenesis GO:0042476 22 22 0,000 0,02530965 0,03574382 ! cell junction organization GO:0034330 23 22 0,000 0,02530965 0,03571645 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,02530965 0,03568912 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,02530965 0,03566184 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,02530965 0,0356346 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,02530965 0,03560739 ! ovulation cycle process GO:0022602 22 22 0,000 0,02530965 0,03558023 ! spindle organization GO:0007051 22 22 0,000 0,02530965 0,03555311 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,02530965 0,03552604 ! cell chemotaxis GO:0060326 23 22 0,000 0,02530965 0,035499 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,02530965 0,035472 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,02530965 0,03544505 ! male sex differentiation GO:0046661 22 22 0,000 0,02530965 0,03541814 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,02530965 0,03539126 ! biopolymer methylation GO:0043414 22 22 0,000 0,02530965 0,03536443 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,02530965 0,03533764 ! detection of external stimulus GO:0009581 23 22 0,000 0,02530965 0,03531089 ! neuron migration GO:0001764 22 22 0,000 0,02530965 0,03528418 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,02530965 0,03525751 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,02530965 0,03523088 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,02530965 0,03520429 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,02530965 0,03517774 ! aerobic respiration GO:0009060 22 22 0,000 0,02530965 0,03515123 ! cytokine production GO:0001816 22 22 0,000 0,02530965 0,03512476 ! cytokinesis GO:0000910 23 22 0,000 0,02530965 0,03509833 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,02530965 0,03507194 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,02644665 0,03661996 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,02644665 0,03659247 ! viral infectious cycle GO:0019058 23 23 0,000 0,02644665 0,03656502 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,02644665 0,03653761 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,02644665 0,03651024 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,02644665 0,03648291 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,02644665 0,03645562 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,02644665 0,03642838 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,02644665 0,03640117 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,02644665 0,03637401 ! endocrine system development GO:0035270 23 23 0,000 0,02644665 0,03634688 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,02644665 0,0363198 ! female gonad development GO:0008585 23 23 0,000 0,02644665 0,03629275 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,02644665 0,03626575 ! lipid homeostasis GO:0055088 23 23 0,000 0,02644665 0,03623879 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,02644665 0,03621186 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,02644665 0,03618498 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,02644665 0,03615814 ! cell projection assembly GO:0030031 25 23 0,000 0,02644665 0,03613133 ! mitochondrial transport GO:0006839 24 24 0,000 0,02758248 0,0376552 ! regulation of action potential GO:0001508 24 24 0,000 0,02758248 0,03762732 ! gliogenesis GO:0042063 24 24 0,000 0,02758248 0,03759949 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,02758248 0,0375717 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,02758248 0,03754396 ! glucose homeostasis GO:0042593 24 24 0,000 0,02758248 0,03751625 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,02758248 0,03748858 ! T cell differentiation GO:0030217 24 24 0,000 0,02758248 0,03746095 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,02758248 0,03743337 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,02758248 0,03740582 ! ovulation cycle GO:0042698 24 24 0,000 0,02758248 0,03737832 ! fertilization GO:0009566 25 24 0,000 0,02758248 0,03735086 ! maintenance of protein location GO:0045185 25 24 0,000 0,02758248 0,03732343 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,02758248 0,03729605 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,02758248 0,03726871 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,02758248 0,0372414 ! glucan metabolic process GO:0044042 25 24 0,000 0,02758248 0,03721414 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,02871716 0,0387167 ! negative regulation of secretion GO:0051048 26 25 0,000 0,02871716 0,03868839 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,02871716 0,03866013 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,02871716 0,03863192 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,02871716 0,03860374 ! cellular component disassembly GO:0022411 26 25 0,000 0,02871716 0,0385756 ! endosome transport GO:0016197 25 25 0,000 0,02871716 0,0385475 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,02871716 0,03851945 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,02871716 0,03849144 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,02871716 0,03846346 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,02871716 0,03843553 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,02871716 0,03840764 ! excretion GO:0007588 25 25 0,000 0,02871716 0,03837979 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,02871716 0,03835197 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,02871716 0,0383242 ! gastrulation GO:0007369 25 25 0,000 0,02871716 0,03829647 ! heart morphogenesis GO:0003007 25 25 0,000 0,02871716 0,03826878 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,02871716 0,03824113 ! regulation of endocytosis GO:0030100 25 25 0,000 0,02871716 0,03821352 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,02871716 0,03818595 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,02871716 0,03815842 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,02871716 0,03813092 ! positive regulation of binding GO:0051099 27 26 0,000 0,02985068 0,03960748 ! positive regulation of defense response GO:0031349 26 26 0,000 0,02985068 0,03957899 ! glycolysis GO:0006096 26 26 0,000 0,02985068 0,03955054 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,02985068 0,03952212 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,02985068 0,03949375 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,02985068 0,03946542 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,02985068 0,03943713 ! cellular defense response GO:0006968 26 26 0,000 0,02985068 0,03940888 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,02985068 0,03938067 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,02985068 0,0393525 ! regulation of protein secretion GO:0050708 26 26 0,000 0,02985068 0,03932437 ! germ cell development GO:0007281 27 26 0,000 0,02985068 0,03929628 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,02985068 0,03926823 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,02985068 0,03924023 ! maintenance of location in cell GO:0051651 27 26 0,000 0,02985068 0,03921226 ! synapse organization GO:0050808 26 26 0,000 0,02985068 0,03918433 ! chloride transport GO:0006821 27 27 0,000 0,03098304 0,0406418 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,03098304 0,0406129 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,03098304 0,04058403 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,03098304 0,04055521 ! learning or memory GO:0007611 28 27 0,000 0,03098304 0,04052643 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,03098304 0,04049768 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,03098304 0,04046898 ! peptide metabolic process GO:0006518 29 27 0,000 0,03098304 0,04044032 ! activation of caspase activity GO:0006919 27 27 0,000 0,03098304 0,0404117 ! mesenchymal cell development GO:0014031 29 27 0,000 0,03098304 0,04038312 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,03098304 0,04035458 ! defense response to bacterium GO:0042742 27 27 0,000 0,03098304 0,04032608 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,03098304 0,04029763 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,03098304 0,04026921 ! cell growth GO:0016049 27 27 0,000 0,03098304 0,04024083 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,03211424 0,04168066 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,03211424 0,04165133 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,03211424 0,04162204 ! carbohydrate transport GO:0008643 28 28 0,000 0,03211424 0,04159279 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,03211424 0,04156358 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,03211424 0,04153442 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,03211424 0,04150529 ! histone modification GO:0016570 28 28 0,000 0,03211424 0,0414762 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,03211424 0,04144716 ! developmental growth GO:0048589 28 28 0,000 0,03211424 0,04141815 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,03211424 0,04138919 ! cartilage development GO:0051216 29 28 0,000 0,03211424 0,04136027 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,03324429 0,04278577 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,03324429 0,04275591 ! viral reproductive process GO:0022415 29 29 0,000 0,03324429 0,0427261 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,03324429 0,04269632 ! leukocyte migration GO:0050900 30 29 0,000 0,03324429 0,04266659 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,03324429 0,0426369 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,03324429 0,04260725 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,03324429 0,04257764 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,03324429 0,04254807 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,03324429 0,04251854 ! tRNA processing GO:0008033 29 29 0,000 0,03324429 0,04248906 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,03324429 0,04245961 ! covalent chromatin modification GO:0016569 29 29 0,000 0,03324429 0,04243021 ! adult behavior GO:0030534 30 29 0,000 0,03324429 0,04240085 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,03324429 0,04237152 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,03324429 0,04234224 ! transition metal ion transport GO:0000041 31 30 0,000 0,03437318 0,04374984 ! RNA catabolic process GO:0006401 30 30 0,000 0,03437318 0,04371965 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,03437318 0,0436895 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,03437318 0,04365939 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,03437318 0,04362932 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,03437318 0,04359929 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,03437318 0,04356931 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,03437318 0,04353936 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,03437318 0,04350946 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,03437318 0,0434796 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,03437318 0,04344977 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,03437318 0,04341999 ! response to temperature stimulus GO:0009266 30 30 0,000 0,03437318 0,04339025 ! regulation of ossification GO:0030278 30 30 0,000 0,03437318 0,04336055 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,03437318 0,0433309 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,03437318 0,04330128 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,03437318 0,0432717 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,03437318 0,04324216 ! vesicle organization GO:0016050 30 30 0,000 0,03437318 0,04321267 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,03437318 0,04318321 ! establishment of organelle localization GO:0051656 31 30 0,000 0,03437318 0,04315379 ! regulation of translational initiation GO:0006446 31 31 0,000 0,03550092 0,04453927 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,03550092 0,04450898 ! membrane fusion GO:0006944 31 31 0,000 0,03550092 0,04447872 ! B cell activation GO:0042113 31 31 0,000 0,03550092 0,0444485 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,03550092 0,04441833 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,03550092 0,04438819 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,03550092 0,0443581 ! ion transmembrane transport GO:0034220 31 31 0,000 0,03550092 0,04432805 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,03550092 0,04429803 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,03550092 0,04426806 ! digestion GO:0007586 31 31 0,000 0,03550092 0,04423813 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,03550092 0,04420824 ! regulation of heart contraction GO:0008016 31 31 0,000 0,03550092 0,04417839 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,03550092 0,04414858 ! camera-type eye development GO:0043010 31 31 0,000 0,03550092 0,04411881 ! extracellular matrix organization GO:0030198 31 31 0,000 0,03550092 0,04408908 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,03550092 0,04405939 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,03550092 0,04402974 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,03550092 0,04400013 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,03550092 0,04397056 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,03662751 0,04533546 ! cell redox homeostasis GO:0045454 32 32 0,000 0,03662751 0,04530503 ! muscle fiber development GO:0048747 32 32 0,000 0,03662751 0,04527464 ! glucose catabolic process GO:0006007 32 32 0,000 0,03662751 0,0452443 ! lipid modification GO:0030258 32 32 0,000 0,03662751 0,04521399 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,03662751 0,04518373 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,03662751 0,04515351 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,03662751 0,04512332 ! cell maturation GO:0048469 32 32 0,000 0,03662751 0,04509318 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,03662751 0,04506308 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,03662751 0,04503302 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,03662751 0,045003 ! kidney development GO:0001822 32 32 0,000 0,03662751 0,04497301 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,03662751 0,04494307 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,03662751 0,04491317 ! maintenance of location GO:0051235 33 32 0,000 0,03662751 0,04488331 ! negative regulation of cell size GO:0045792 33 33 0,000 0,03775294 0,04623167 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,03775294 0,04620098 ! amino acid transport GO:0006865 33 33 0,000 0,03775294 0,04617032 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,03775294 0,0461397 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,03775294 0,04610913 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,03775294 0,04607859 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,03775294 0,04604809 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,03775294 0,04601764 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,03775294 0,04598722 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,03775294 0,04595685 ! regulation of actin filament length GO:0030832 34 34 0,000 0,03887723 0,04729421 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,03887723 0,04726301 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,03887723 0,04723186 ! response to metal ion GO:0010038 34 34 0,000 0,03887723 0,04720074 ! ear development GO:0043583 34 34 0,000 0,03887723 0,04716967 ! muscle cell differentiation GO:0042692 35 34 0,000 0,03887723 0,04713864 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,03887723 0,04710764 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,03887723 0,04707669 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,03887723 0,04704578 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,03887723 0,04701491 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,03887723 0,04698408 ! secondary metabolic process GO:0019748 34 34 0,000 0,03887723 0,04695329 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,03887723 0,04692255 ! viral reproduction GO:0016032 34 34 0,000 0,03887723 0,04689184 ! detection of stimulus GO:0051606 36 34 0,000 0,03887723 0,04686117 ! acute inflammatory response GO:0002526 35 35 0,000 0,04000036 0,04818344 ! regulation of cellular component size GO:0032535 35 35 0,000 0,04000036 0,04815197 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,04000036 0,04812054 ! mesoderm development GO:0007498 35 35 0,000 0,04000036 0,04808915 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,04000036 0,0480578 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,04000036 0,04802649 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,04000036 0,04799522 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,04000036 0,047964 ! inorganic anion transport GO:0015698 35 35 0,000 0,04000036 0,04793281 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,04000036 0,04790167 ! regulation of immune effector process GO:0002697 35 35 0,000 0,04000036 0,04787056 ! hydrogen transport GO:0006818 36 36 0,000 0,04112235 0,04918137 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,04112235 0,04914947 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,04112235 0,04911762 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,04112235 0,04908581 ! regulation of mitosis GO:0007088 37 36 0,000 0,04112235 0,04905404 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,04112235 0,04902231 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,04112235 0,04899062 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,04112235 0,04895897 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,04112235 0,04892736 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,04112235 0,0488958 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,04112235 0,04886427 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,04112235 0,04883279 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,04112235 0,04880134 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,04112235 0,04876994 ! gonad development GO:0008406 36 36 0,000 0,04112235 0,04873858 ! regulation of lipase activity GO:0060191 36 36 0,000 0,04112235 0,04870725 ! activation of immune response GO:0002253 36 36 0,000 0,04112235 0,04867597 ! coagulation GO:0050817 39 36 0,000 0,04112235 0,04864473 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,04224319 0,04993855 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,04224319 0,04990653 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,04224319 0,04987456 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 0,000 0,04224319 0,04984263 ! lung development GO:0030324 38 37 0,000 0,04224319 0,04981074 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,04224319 0,0497789 ! eye development GO:0001654 37 37 0,000 0,04224319 0,04974709 ! negative regulation of growth GO:0045926 37 37 0,000 0,04224319 0,04971532 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,04224319 0,04968359 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,04224319 0,04965191 ! adaptive immune response GO:0002250 37 37 0,000 0,04224319 0,04962026 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,04336288 0,05090305 ! neurotransmitter transport GO:0006836 40 38 0,000 0,04336288 0,05087065 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,04336288 0,05083829 ! exocytosis GO:0006887 40 38 0,000 0,04336288 0,05080597 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,04336288 0,05077369 ! chromosome segregation GO:0007059 38 38 0,000 0,04336288 0,05074145 ! urogenital system development GO:0001655 38 38 0,000 0,04336288 0,05070925 ! hexose catabolic process GO:0019320 38 38 0,000 0,04336288 0,0506771 ! RNA elongation GO:0006354 38 38 0,000 0,04336288 0,05064498 ! meiotic cell cycle GO:0051321 38 38 0,000 0,04336288 0,05061291 ! axon guidance GO:0007411 39 38 0,000 0,04336288 0,05058088 ! regulation of neurological system process GO:0031644 38 38 0,000 0,04336288 0,05054888 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,04336288 0,05051693 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,04336288 0,05048502 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,04448143 0,05175459 ! hemostasis GO:0007599 42 39 0,000 0,04448143 0,05172193 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,04448143 0,05168932 ! activation of MAPK activity GO:0000187 39 39 0,000 0,04448143 0,05165675 ! respiratory tube development GO:0030323 40 39 0,000 0,04448143 0,05162422 ! response to unfolded protein GO:0006986 39 39 0,000 0,04448143 0,05159173 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,04448143 0,05155929 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,04448143 0,05152688 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,04448143 0,05149451 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,04448143 0,05146219 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,04448143 0,0514299 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,04448143 0,05139766 ! respiratory system development GO:0060541 40 39 0,000 0,04448143 0,05136546 ! developmental maturation GO:0021700 39 39 0,000 0,04448143 0,05133329 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,04448143 0,05130117 ! limb development GO:0060173 39 39 0,000 0,04448143 0,05126908 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,04448143 0,05123704 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,04448143 0,05120504 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,04559883 0,05245858 ! DNA catabolic process GO:0006308 41 40 0,000 0,04559883 0,05242585 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,04559883 0,05239317 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,04559883 0,05236052 ! organelle localization GO:0051640 41 40 0,000 0,04559883 0,05232792 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,04671509 0,05357555 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,04671509 0,05354223 ! amine catabolic process GO:0009310 42 41 0,000 0,04671509 0,05350895 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,04671509 0,05347572 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,04671509 0,05344252 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,04671509 0,05340937 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,04671509 0,05337626 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,0478302 0,05461652 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,0478302 0,0545827 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,0478302 0,05454893 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,0478302 0,05451519 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,0478302 0,0544815 ! protein ubiquitination GO:0016567 43 42 0,000 0,0478302 0,05444785 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,0478302 0,05441424 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,0478302 0,05438067 ! forebrain development GO:0030900 43 42 0,000 0,0478302 0,05434714 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,0478302 0,05431366 ! reproductive structure development GO:0048608 43 43 0,000 0,04894418 0,05554441 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,04894418 0,05551023 ! alcohol catabolic process GO:0046164 43 43 0,000 0,04894418 0,05547609 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,04894418 0,05544199 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,04894418 0,05540793 ! humoral immune response GO:0006959 44 44 0,000 0,05005701 0,05663295 ! mRNA transport GO:0051028 44 44 0,000 0,05005701 0,0565982 ! protein import into nucleus GO:0006606 44 44 0,000 0,05005701 0,0565635 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,05005701 0,05652884 ! vitamin metabolic process GO:0006766 44 44 0,000 0,05005701 0,05649423 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,05005701 0,05645965 ! amine biosynthetic process GO:0009309 46 45 0,000 0,05116871 0,05767824 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,05116871 0,05764299 ! regulation of DNA binding GO:0051101 47 45 0,000 0,05116871 0,05760777 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,05116871 0,0575726 ! nuclear import GO:0051170 45 45 0,000 0,05116871 0,05753748 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,05116871 0,05750239 ! protein processing GO:0016485 45 45 0,000 0,05116871 0,05746735 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,05227926 0,05867885 ! tube morphogenesis GO:0035239 47 46 0,000 0,05227926 0,05864314 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,05227926 0,05860747 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,05227926 0,05857184 ! regulation of membrane potential GO:0042391 46 46 0,000 0,05227926 0,05853626 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,05338868 0,05974216 ! regulation of blood pressure GO:0008217 48 47 0,000 0,05338868 0,05970591 ! sex differentiation GO:0007548 47 47 0,000 0,05338868 0,0596697 ! amine transport GO:0015837 47 47 0,000 0,05338868 0,05963354 ! rhythmic process GO:0048511 47 47 0,000 0,05338868 0,05959742 ! regulation of catabolic process GO:0009894 48 47 0,000 0,05338868 0,05956134 ! calcium ion transport GO:0006816 48 48 0,000 0,05449696 0,06076098 ! actin filament organization GO:0007015 50 48 0,000 0,05449696 0,06072424 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,05449696 0,06068755 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,05449696 0,06065091 ! protein localization in nucleus GO:0034504 48 48 0,000 0,05449696 0,0606143 ! DNA recombination GO:0006310 48 48 0,000 0,05449696 0,06057774 ! leukocyte differentiation GO:0002521 50 49 0,000 0,05560411 0,06177117 ! ossification GO:0001503 50 49 0,000 0,05560411 0,06173396 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,05560411 0,06169679 ! cell cycle arrest GO:0007050 49 49 0,000 0,05560411 0,06165967 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,05560411 0,06162259 ! divalent metal ion transport GO:0070838 49 49 0,000 0,05560411 0,06158556 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,05560411 0,06154857 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,05560411 0,06151163 ! response to bacterium GO:0009617 50 49 0,000 0,05560411 0,06147473 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,05560411 0,06143787 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,05560411 0,06140106 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,05560411 0,06136429 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,05671012 0,06254743 ! negative regulation of transport GO:0051051 51 50 0,000 0,05671012 0,06251002 ! chromatin assembly GO:0031497 50 50 0,000 0,05671012 0,06247265 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 0,000 0,05671012 0,06243534 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,05671012 0,06239806 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,05671012 0,06236083 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,05671012 0,06232364 ! transcription initiation GO:0006352 50 50 0,000 0,05671012 0,0622865 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,05671012 0,06224941 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,05671012 0,06221235 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,057815 0,0633867 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,057815 0,06334901 ! positive regulation of immune response GO:0050778 51 51 0,000 0,057815 0,06331137 ! rRNA metabolic process GO:0016072 51 51 0,000 0,057815 0,06327378 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,057815 0,06323623 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,057815 0,06319872 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,057815 0,06316126 ! protein maturation GO:0051604 51 51 0,000 0,057815 0,06312384 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,05891874 0,06429085 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,05891874 0,06425281 ! cell fate commitment GO:0045165 52 52 0,000 0,05891874 0,06421481 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,05891874 0,06417686 ! sodium ion transport GO:0006814 53 53 0,000 0,06002136 0,06533926 ! tRNA metabolic process GO:0006399 53 53 0,000 0,06002136 0,06530069 ! response to hypoxia GO:0001666 53 53 0,000 0,06002136 0,06526216 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,06002136 0,06522368 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,06002136 0,06518525 ! regulation of T cell activation GO:0050863 53 53 0,000 0,06002136 0,06514686 ! regulation of protein transport GO:0051223 53 53 0,000 0,06002136 0,06510851 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,06112284 0,06626435 ! response to oxygen levels GO:0070482 55 54 0,000 0,06112284 0,0662254 ! response to virus GO:0009615 54 54 0,000 0,06112284 0,06618649 ! hormone metabolic process GO:0042445 55 54 0,000 0,06112284 0,06614762 ! sulfur metabolic process GO:0006790 55 54 0,000 0,06112284 0,0661088 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,06112284 0,06607003 ! nucleosome organization GO:0034728 55 55 0,000 0,0622232 0,06722002 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,0622232 0,06718064 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,0622232 0,06714131 ! in utero embryonic development GO:0001701 55 55 0,000 0,0622232 0,06710202 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,0622232 0,06706278 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,06332242 0,06820761 ! reproductive developmental process GO:0003006 56 56 0,000 0,06332242 0,06816777 ! extracellular structure organization GO:0043062 56 56 0,000 0,06332242 0,06812798 ! regulation of nervous system development GO:0051960 57 56 0,000 0,06332242 0,06808823 ! regulation of binding GO:0051098 60 57 0,000 0,06442052 0,06922858 ! ATP metabolic process GO:0046034 57 57 0,000 0,06442052 0,06918824 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,06442052 0,06914794 ! regulation of protein localization GO:0032880 58 57 0,000 0,06442052 0,06910769 ! innate immune response GO:0045087 58 58 0,000 0,06551749 0,07024359 ! dephosphorylation GO:0016311 60 59 0,000 0,06661334 0,07137697 ! carboxylic acid transport GO:0046942 59 59 0,000 0,06661334 0,07133549 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,06661334 0,07129407 ! regulation of cell development GO:0060284 60 59 0,000 0,06661334 0,07125269 ! sterol metabolic process GO:0016125 59 59 0,000 0,06661334 0,07121136 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,06661334 0,07117008 ! protein localization in organelle GO:0033365 59 59 0,000 0,06661334 0,07112884 ! immune effector process GO:0002252 59 59 0,000 0,06661334 0,07108766 ! potassium ion transport GO:0006813 60 60 0,000 0,06770806 0,07221409 ! protein polymerization GO:0051258 65 60 0,000 0,06770806 0,07217233 ! cellular respiration GO:0045333 62 61 0,000 0,06880166 0,07329564 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,06880166 0,07325329 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,06880166 0,073211 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,06880166 0,07316875 ! lipid transport GO:0006869 62 62 0,000 0,06989413 0,07428771 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,06989413 0,07424489 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,06989413 0,07420212 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,06989413 0,0741594 ! protein import GO:0017038 62 62 0,000 0,06989413 0,07411673 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,06989413 0,07407411 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,06989413 0,07403154 ! regulation of secretion GO:0051046 65 63 0,000 0,07098548 0,07514431 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,07098548 0,07510118 ! glucose metabolic process GO:0006006 63 63 0,000 0,07098548 0,07505809 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,07098548 0,07501505 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,07098548 0,07497206 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,07207572 0,07607992 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,07207572 0,07603637 ! angiogenesis GO:0001525 65 64 0,000 0,07207572 0,07599288 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,07207572 0,07594943 ! anion transport GO:0006820 65 65 0,000 0,07316483 0,07705302 ! regulation of hormone levels GO:0010817 66 65 0,000 0,07316483 0,07700901 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,07425282 0,07810956 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,07425282 0,07806501 ! DNA packaging GO:0006323 66 66 0,000 0,07425282 0,0780205 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,07425282 0,07797604 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,07425282 0,07793164 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,0753397 0,07902736 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,0753397 0,07898241 ! muscle contraction GO:0006936 67 67 0,000 0,0753397 0,0789375 ! striated muscle tissue development GO:0014706 69 67 0,000 0,0753397 0,07889265 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,0753397 0,07884785 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,0753397 0,0788031 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,07642546 0,07989343 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,07642546 0,07984814 ! sensory perception of sound GO:0007605 71 69 0,000 0,07751011 0,08093548 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,07751011 0,08088965 ! response to nutrient levels GO:0031667 69 69 0,000 0,07751011 0,08084387 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,07751011 0,08079815 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,07751011 0,08075247 ! positive regulation of transport GO:0051050 71 70 0,000 0,07859363 0,08183507 ! cell part morphogenesis GO:0032990 75 70 0,000 0,07859363 0,08178886 ! wound healing GO:0042060 74 70 0,000 0,07859363 0,0817427 ! growth GO:0040007 70 70 0,000 0,07859363 0,0816966 ! muscle tissue development GO:0060537 72 70 0,000 0,07859363 0,08165055 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,07859363 0,08160455 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,07967605 0,08268185 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,07967605 0,08263532 ! regulation of cell migration GO:0030334 71 71 0,000 0,07967605 0,08258884 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,07967605 0,08254242 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 0,000 0,07967605 0,08249605 ! secretion by cell GO:0032940 75 72 0,000 0,08075735 0,08356867 ! muscle system process GO:0003012 72 72 0,000 0,08075735 0,08352177 ! sensory organ development GO:0007423 72 72 0,000 0,08075735 0,08347493 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,08075735 0,08342814 ! regulation of cytokine production GO:0001817 72 72 0,000 0,08075735 0,0833814 ! electron transport chain GO:0022900 75 74 0,000 0,08291662 0,0855629 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,08291662 0,08551502 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,0839946 0,08657832 ! response to oxidative stress GO:0006979 76 75 0,000 0,0839946 0,08652993 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,0839946 0,08648159 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,08507146 0,08754143 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,08614721 0,08859894 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,08614721 0,08854953 ! microtubule-based movement GO:0007018 82 78 0,000 0,08722186 0,08960417 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,08722186 0,08955425 ! metal ion homeostasis GO:0055065 78 78 0,000 0,08722186 0,08950439 ! regulation of immune response GO:0050776 78 78 0,000 0,08722186 0,08945458 ! regulation of locomotion GO:0040012 79 79 0,000 0,0882954 0,09050524 ! regulation of cell motion GO:0051270 79 79 0,000 0,0882954 0,09045493 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,08936783 0,09150273 ! neuron projection development GO:0031175 85 80 0,000 0,08936783 0,09145193 ! MAPKKK cascade GO:0000165 82 81 0,000 0,09043917 0,09249688 ! tube development GO:0035295 83 81 0,000 0,09043917 0,09244558 ! lymphocyte activation GO:0046649 82 81 0,000 0,09043917 0,09239434 ! lipid catabolic process GO:0016042 82 81 0,000 0,09043917 0,09234315 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,09257852 0,0944752 ! ncRNA processing GO:0034470 83 83 0,000 0,09257852 0,09442292 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,09257852 0,09437069 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,09364655 0,09540663 ! regulation of cellular localization GO:0060341 86 85 0,000 0,09471347 0,09644029 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,09471347 0,09638704 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,09471347 0,09633385 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,09471347 0,09628071 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,0957793 0,0973105 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,0957793 0,09725689 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,0957793 0,09720333 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,0957793 0,09714984 ! heart development GO:0007507 90 87 0,000 0,09684403 0,09817577 ! male gamete generation GO:0048232 90 88 0,000 0,09790766 0,09919946 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,09790766 0,09914495 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,09790766 0,09909051 ! chemotaxis GO:0006935 90 89 0,000 0,0989702 0,10011091 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,0989702 0,10005599 ! brain development GO:0007420 91 90 0,000 0,10003164 0,10107363 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,10109198 0,10208905 ! visual perception GO:0007601 93 92 0,000 0,10215123 0,10310226 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,10215123 0,10304583 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,10215123 0,10298945 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,10215123 0,10293315 ! tissue morphogenesis GO:0048729 94 93 0,000 0,10320939 0,10394257 ! regulation of response to stress GO:0080134 97 94 0,000 0,10426646 0,1049498 ! blood vessel development GO:0001568 95 94 0,000 0,10426646 0,10489252 ! pattern specification process GO:0007389 96 94 0,000 0,10426646 0,10483529 ! cofactor metabolic process GO:0051186 95 94 0,000 0,10426646 0,10477813 ! vasculature development GO:0001944 97 96 0,000 0,10637733 0,1068411 ! endocytosis GO:0006897 99 98 0,000 0,10848384 0,10889745 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,10848384 0,10883817 ! blood circulation GO:0008015 99 98 0,000 0,10848384 0,10877896 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,10848384 0,1087198 ! muscle organ development GO:0007517 102 100 0,000 0,11058601 0,11076631 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,11058601 0,11070615 ! response to other organism GO:0051707 101 100 0,000 0,11058601 0,11064604 ! hemopoiesis GO:0030097 104 100 0,000 0,11058601 0,11058601