pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/92359-11-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! establishment of cell polarity GO:0030010 5 5 2,000 3,036E-08 5,595E-05 ! actin filament organization GO:0007015 50 48 3,000 6,641E-07 6,12E-04 ! cell-cell junction organization GO:0045216 13 13 2,000 8,623E-07 5,297E-04 ! establishment or maintenance of cell polarity GO:0007163 21 20 2,000 3,416E-06 1,574E-03 ! cell junction organization GO:0034330 23 22 2,000 4,607E-06 1,698E-03 ! substrate-bound cell migration, cell extension GO:0006930 5 5 1,000 2,318E-05 7,121E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 1,000 2,318E-05 6,103E-03 ! positive regulation of cell growth GO:0030307 6 6 1,000 3,474E-05 8,004E-03 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 3,474E-05 7,114E-03 ! regulation of Rho GTPase activity GO:0032319 6 6 1,000 3,474E-05 6,403E-03 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 3,474E-05 5,821E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 1,000 3,474E-05 5,336E-03 ! regulation of actin cytoskeleton organization GO:0032956 46 45 2,000 4,16E-05 5,898E-03 ! regulation of actin filament-based process GO:0032970 47 46 2,000 4,446E-05 5,853E-03 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 4,86E-05 5,971E-03 ! keratinocyte proliferation GO:0043616 7 7 1,000 4,86E-05 5,598E-03 ! myofibril assembly GO:0030239 7 7 1,000 4,86E-05 5,268E-03 GO:0055002|striated muscle cell development, ! regulation of stress fiber formation GO:0051492 9 8 1,000 6,474E-05 6,629E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 6,474E-05 6,28E-03 ! muscle cell development GO:0055001 8 8 1,000 6,474E-05 5,966E-03 ! positive regulation of cell size GO:0045793 9 9 1,000 8,316E-05 7,299E-03 ! Golgi vesicle budding GO:0048194 9 9 1,000 8,316E-05 6,967E-03 ! substrate-bound cell migration GO:0006929 9 9 1,000 8,316E-05 6,664E-03 ! negative regulation of caspase activity GO:0043154 9 9 1,000 8,316E-05 6,386E-03 ! regulation of dephosphorylation GO:0035303 9 9 1,000 8,316E-05 6,131E-03 ! regulation of actin filament bundle formation GO:0032231 10 9 1,000 8,316E-05 5,895E-03 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 1,039E-04 7,09E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,039E-04 6,836E-03 ! regulation of cytoskeleton organization GO:0051493 66 64 2,000 1,201E-04 7,635E-03 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 1,258E-04 7,73E-03 ! skin development GO:0043588 11 11 1,000 1,268E-04 7,54E-03 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 1,000 1,268E-04 7,305E-03 ! membrane budding GO:0006900 11 11 1,000 1,268E-04 7,083E-03 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 1,521E-04 8,243E-03 ! actomyosin structure organization GO:0031032 12 12 1,000 1,521E-04 8,007E-03 ! negative regulation of translation GO:0017148 12 12 1,000 1,521E-04 7,785E-03 ! negative regulation of protein modification process GO:0031400 13 13 1,000 1,796E-04 8,944E-03 ! neural crest cell migration GO:0001755 14 13 1,000 1,796E-04 8,709E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 1,796E-04 8,485E-03 GO:0001952|regulation of cell-matrix adhesion, ! primary neural tube formation GO:0014020 15 14 1,000 2,093E-04 9,644E-03 ! striated muscle cell differentiation GO:0051146 16 15 1,000 2,413E-04 0,01084632 ! positive regulation of cytoskeleton organization GO:0051495 16 16 1,000 2,755E-04 0,0120901 ! embryonic epithelial tube formation GO:0001838 17 16 1,000 2,755E-04 0,01180894 GO:0001841|neural tube formation, ! regulation of actin filament depolymerization GO:0030834 17 17 1,000 3,12E-04 0,01306788 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 3,12E-04 0,01277748 ! neural crest cell development GO:0014032 19 17 1,000 3,12E-04 0,01249971 GO:0014033|neural crest cell differentiation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 3,507E-04 0,01375098 ! eye morphogenesis GO:0048592 19 19 1,000 3,916E-04 0,01503543 ! neural tube development GO:0021915 21 20 1,000 4,347E-04 0,01635082 ! protein targeting to membrane GO:0006612 22 20 1,000 4,347E-04 0,0160238 ! anti-apoptosis GO:0006916 100 99 2,000 4,386E-04 0,01584913 ! morphogenesis of embryonic epithelium GO:0016331 22 21 1,000 4,801E-04 0,01701449 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 4,801E-04 0,01669346 ! RNA export from nucleus GO:0006405 22 22 1,000 5,276E-04 0,01800703 ! cytokinesis GO:0000910 23 22 1,000 5,276E-04 0,01767963 ! positive regulation of growth GO:0045927 23 23 1,000 5,774E-04 0,01900104 ! Rho protein signal transduction GO:0007266 24 23 1,000 5,774E-04 0,01866769 ! cell projection assembly GO:0030031 25 23 1,000 5,774E-04 0,01834583 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 6,293E-04 0,01965726 ! glycolysis GO:0006096 26 26 1,000 7,397E-04 0,02272165 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 7,397E-04 0,02234917 ! response to insulin stimulus GO:0032868 28 26 1,000 7,397E-04 0,0219887 ! mesenchymal cell development GO:0014031 29 27 1,000 7,982E-04 0,02335046 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! keratinocyte differentiation GO:0030216 28 28 1,000 8,588E-04 0,02473214 ! regulation of protein complex disassembly GO:0043244 30 30 1,000 9,866E-04 0,02797484 ! vesicle organization GO:0016050 30 30 1,000 9,866E-04 0,02755098 ! skeletal muscle fiber development GO:0048741 31 31 1,000 1,054E-03 0,02898618 ! epidermal cell differentiation GO:0009913 31 31 1,000 1,054E-03 0,02855991 ! muscle fiber development GO:0048747 32 32 1,000 1,123E-03 0,02999621 ! glucose catabolic process GO:0006007 32 32 1,000 1,123E-03 0,02956769 ! nuclear export GO:0051168 32 32 1,000 1,123E-03 0,02915124 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 1,194E-03 0,03057428 ! regulation of actin filament length GO:0030832 34 34 1,000 1,268E-03 0,03201222 ! muscle cell differentiation GO:0042692 35 34 1,000 1,268E-03 0,03157962 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 1,268E-03 0,03115856 ! viral reproduction GO:0016032 34 34 1,000 1,268E-03 0,03074858 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 1,344E-03 0,03216051 ! regulation of cellular component size GO:0032535 35 35 1,000 1,344E-03 0,0317482 ! positive regulation of organelle organization GO:0010638 36 36 1,000 1,421E-03 0,03316127 ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 1,501E-03 0,0345878 ! eye development GO:0001654 37 37 1,000 1,501E-03 0,03416079 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 1,501E-03 0,0337442 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 1,501E-03 0,03333764 ! negative regulation of kinase activity GO:0033673 38 38 1,000 1,583E-03 0,03474047 ! hexose catabolic process GO:0019320 38 38 1,000 1,583E-03 0,03433176 ! axon guidance GO:0007411 39 38 1,000 1,583E-03 0,03393256 ! response to unfolded protein GO:0006986 39 39 1,000 1,668E-03 0,03532479 ! negative regulation of transferase activity GO:0051348 40 40 1,000 1,754E-03 0,03672938 ! regulation of caspase activity GO:0043281 41 41 1,000 1,842E-03 0,03814578 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 1,842E-03 0,03772194 ! monosaccharide catabolic process GO:0046365 41 41 1,000 1,842E-03 0,03730741 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 1,933E-03 0,03871319 ! response to protein stimulus GO:0051789 42 42 1,000 1,933E-03 0,03829692 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 1,933E-03 0,03788951 ! mitochondrion organization GO:0007005 44 43 1,000 2,025E-03 0,03928519 ! alcohol catabolic process GO:0046164 43 43 1,000 2,025E-03 0,03887597 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 2,12E-03 0,04027217 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 2,216E-03 0,04167886 ! tube morphogenesis GO:0035239 47 46 1,000 2,315E-03 0,04309559 ! regulation of peptidase activity GO:0052547 46 46 1,000 2,315E-03 0,04266463 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 2,315E-03 0,04224221 ! positive regulation of ligase activity GO:0051351 47 46 1,000 2,315E-03 0,04182807 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 2,519E-03 0,04506522 ! skeletal muscle tissue development GO:0007519 50 49 1,000 2,623E-03 0,04649055 GO:0060538|skeletal muscle organ development, ! regulation of ligase activity GO:0051340 50 49 1,000 2,623E-03 0,04604778 ! RNA transport GO:0050658 50 50 1,000 2,73E-03 0,04747248 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! anatomical structure homeostasis GO:0060249 51 50 1,000 2,73E-03 0,04702881 ! RNA localization GO:0006403 52 52 1,000 2,95E-03 0,05034698 ! regulation of GTPase activity GO:0043087 53 52 1,000 2,95E-03 0,04988508 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 3,063E-03 0,05132527 ! carbohydrate catabolic process GO:0016052 53 53 1,000 3,063E-03 0,05086288 ! regulation of cell adhesion GO:0030155 56 55 1,000 3,295E-03 0,05422819 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 3,911E-03 0,06378471 ! cellular respiration GO:0045333 62 61 1,000 4,04E-03 0,0653114 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 4,04E-03 0,06474348 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 4,04E-03 0,06418534 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 4,171E-03 0,06570062 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 1,000 4,171E-03 0,06514383 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 4,171E-03 0,06459641 ! glucose metabolic process GO:0006006 63 63 1,000 4,304E-03 0,06610066 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 4,439E-03 0,06761001 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 4,715E-03 0,07122219 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 4,855E-03 0,07275327 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 1,000 4,855E-03 0,07216655 ! muscle contraction GO:0006936 67 67 1,000 4,855E-03 0,07158922 ! striated muscle tissue development GO:0014706 69 67 1,000 4,855E-03 0,07102105 ! Ras protein signal transduction GO:0007265 69 67 1,000 4,855E-03 0,07046183 ! regulation of cell size GO:0008361 68 68 1,000 4,998E-03 0,07196704 ! regulation of translation GO:0006417 69 69 1,000 5,143E-03 0,07347663 ! cell part morphogenesis GO:0032990 75 70 1,000 5,29E-03 0,07499041 ! muscle tissue development GO:0060537 72 70 1,000 5,29E-03 0,07441797 ! ribosome biogenesis GO:0042254 71 71 1,000 5,438E-03 0,07592861 ! negative regulation of signal transduction GO:0009968 71 71 1,000 5,438E-03 0,07535772 ! muscle system process GO:0003012 72 72 1,000 5,589E-03 0,07686525 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 5,589E-03 0,07629588 ! sensory organ development GO:0007423 72 72 1,000 5,589E-03 0,07573488 ! negative regulation of cell communication GO:0010648 76 76 1,000 6,21E-03 0,08353768 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 6,37E-03 0,0850696 ! regulation of protein modification process GO:0031399 79 78 1,000 6,532E-03 0,08660456 ! nuclear transport GO:0051169 79 79 1,000 6,696E-03 0,08814241 GO:0006913|nucleocytoplasmic transport, ! neuron projection development GO:0031175 85 80 1,000 6,861E-03 0,08968303 ! tube development GO:0035295 83 81 1,000 7,029E-03 0,09122629 ! hexose metabolic process GO:0019318 87 86 1,000 7,895E-03 0,1017466 ! rRNA transcription GO:0009303 5 5 0,000 7,971E-03 0,1020174 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 7,971E-03 0,10131383 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 7,971E-03 0,1006199 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 7,971E-03 0,09993541 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 7,971E-03 0,09926017 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 7,971E-03 0,098594 ! reproductive cellular process GO:0048610 5 5 0,000 7,971E-03 0,0979367 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 7,971E-03 0,09728811 ! negative regulation of blood pressure GO:0045776 6 5 0,000 7,971E-03 0,09664806 ! prostate gland development GO:0030850 5 5 0,000 7,971E-03 0,09601637 ! metencephalon development GO:0022037 5 5 0,000 7,971E-03 0,09539289 ! water transport GO:0006833 5 5 0,000 7,971E-03 0,09477745 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 7,971E-03 0,09416991 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 7,971E-03 0,0935701 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 7,971E-03 0,09297788 ! glycerol metabolic process GO:0006071 5 5 0,000 7,971E-03 0,09239312 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 7,971E-03 0,09181566 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 7,971E-03 0,09124537 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 7,971E-03 0,09068213 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 7,971E-03 0,0901258 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 7,971E-03 0,08957625 ! filopodium assembly GO:0046847 7 5 0,000 7,971E-03 0,08903337 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 7,971E-03 0,08849702 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 7,971E-03 0,0879671 ! GTP metabolic process GO:0046039 5 5 0,000 7,971E-03 0,08744348 ! establishment of tissue polarity GO:0007164 5 5 0,000 7,971E-03 0,08692607 ! mRNA stabilization GO:0048255 5 5 0,000 7,971E-03 0,08641474 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 7,971E-03 0,08590939 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 7,971E-03 0,08540991 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 7,971E-03 0,08491622 ! social behavior GO:0035176 5 5 0,000 7,971E-03 0,08442819 ! macrophage chemotaxis GO:0048246 6 5 0,000 7,971E-03 0,08394574 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 7,971E-03 0,08346878 ! memory GO:0007613 5 5 0,000 7,971E-03 0,08299721 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 7,971E-03 0,08253093 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 7,971E-03 0,08206986 ! membrane hyperpolarization GO:0060081 5 5 0,000 7,971E-03 0,08161392 ! response to lipid GO:0033993 5 5 0,000 7,971E-03 0,08116301 ! erythrocyte maturation GO:0043249 5 5 0,000 7,971E-03 0,08071706 ! hippocampus development GO:0021766 6 5 0,000 7,971E-03 0,08027599 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 7,971E-03 0,0798397 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 7,971E-03 0,07940814 ! middle ear morphogenesis GO:0042474 5 5 0,000 7,971E-03 0,07898121 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 7,971E-03 0,07855885 ! mechanosensory behavior GO:0007638 5 5 0,000 7,971E-03 0,07814099 ! heart looping GO:0001947 5 5 0,000 7,971E-03 0,07772754 ! negative regulation of endocytosis GO:0045806 5 5 0,000 7,971E-03 0,07731845 ! response to interferon-gamma GO:0034341 5 5 0,000 7,971E-03 0,07691364 ! pseudouridine synthesis GO:0001522 5 5 0,000 7,971E-03 0,07651305 ! endocrine pancreas development GO:0031018 5 5 0,000 7,971E-03 0,07611661 ! pH reduction GO:0045851 5 5 0,000 7,971E-03 0,07572425 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 7,971E-03 0,07533592 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 7,971E-03 0,07495156 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 7,971E-03 0,07457109 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 7,971E-03 0,07419447 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 7,971E-03 0,07382163 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 7,971E-03 0,07345253 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 7,971E-03 0,07308709 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 7,971E-03 0,07272527 ! adrenal gland development GO:0030325 5 5 0,000 7,971E-03 0,07236702 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 7,971E-03 0,07201228 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 7,971E-03 0,071661 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 7,971E-03 0,07131313 ! astrocyte differentiation GO:0048708 5 5 0,000 7,971E-03 0,07096862 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 7,971E-03 0,07062743 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 7,971E-03 0,0702895 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 7,971E-03 0,06995479 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 7,971E-03 0,06962325 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 7,971E-03 0,06929484 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 7,971E-03 0,06896951 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 7,971E-03 0,06864722 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 7,971E-03 0,06832793 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 7,971E-03 0,0680116 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 7,971E-03 0,06769818 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 7,971E-03 0,06738764 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 7,971E-03 0,06707993 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 7,971E-03 0,06677502 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 7,971E-03 0,06647287 ! response to ATP GO:0033198 5 5 0,000 7,971E-03 0,06617345 ! regulation of type I interferon production GO:0032479 5 5 0,000 7,971E-03 0,06587671 ! regulation of appetite GO:0032098 5 5 0,000 7,971E-03 0,06558261 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 7,971E-03 0,06529113 ! paraxial mesoderm development GO:0048339 5 5 0,000 7,971E-03 0,06500224 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 7,971E-03 0,06471588 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 7,971E-03 0,06443204 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 7,971E-03 0,06415068 ! receptor clustering GO:0043113 5 5 0,000 7,971E-03 0,06387176 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 7,971E-03 0,06359526 ! fear response GO:0042596 5 5 0,000 7,971E-03 0,06332114 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 7,971E-03 0,06304938 ! lens development in camera-type eye GO:0002088 5 5 0,000 7,971E-03 0,06277994 ! retinol metabolic process GO:0042572 5 5 0,000 7,971E-03 0,06251279 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 7,971E-03 0,0622479 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 7,971E-03 0,06198525 ! positive regulation of exocytosis GO:0045921 6 5 0,000 7,971E-03 0,06172481 ! parturition GO:0007567 5 5 0,000 7,971E-03 0,06146655 ! cellular glucose homeostasis GO:0001678 5 5 0,000 7,971E-03 0,06121044 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 7,971E-03 0,06095645 ! Schwann cell differentiation GO:0014037 5 5 0,000 7,971E-03 0,06070457 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 7,971E-03 0,06045475 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 7,971E-03 0,06020699 ! protein heterooligomerization GO:0051291 5 5 0,000 7,971E-03 0,05996125 ! regulation of gliogenesis GO:0014013 5 5 0,000 7,971E-03 0,0597175 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 7,971E-03 0,05947573 ! response to UV-B GO:0010224 5 5 0,000 7,971E-03 0,05923591 ! oligodendrocyte development GO:0014003 5 5 0,000 7,971E-03 0,05899801 ! hyaluronan metabolic process GO:0030212 5 5 0,000 7,971E-03 0,05876202 ! activated T cell proliferation GO:0050798 5 5 0,000 7,971E-03 0,05852791 ! interaction with symbiont GO:0051702 5 5 0,000 7,971E-03 0,05829566 ! cellular extravasation GO:0045123 5 5 0,000 7,971E-03 0,05806524 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 7,971E-03 0,05783664 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 7,971E-03 0,05760982 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 7,971E-03 0,05738479 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 7,971E-03 0,0571615 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 7,971E-03 0,05693994 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 7,971E-03 0,0567201 ! response to amine stimulus GO:0014075 5 5 0,000 7,971E-03 0,05650194 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 7,971E-03 0,05628546 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 7,971E-03 0,05607063 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 7,971E-03 0,05585743 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 7,971E-03 0,05564585 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 7,971E-03 0,05543587 ! neuron recognition GO:0008038 5 5 0,000 7,971E-03 0,05522746 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 7,971E-03 0,05502062 ! decidualization GO:0046697 5 5 0,000 7,971E-03 0,05481532 ! hair follicle maturation GO:0048820 5 5 0,000 7,971E-03 0,05461154 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 7,971E-03 0,05440928 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 7,971E-03 0,05420851 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 7,971E-03 0,05400921 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 7,971E-03 0,05381137 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 7,971E-03 0,05361498 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 7,971E-03 0,05342002 ! postreplication repair GO:0006301 5 5 0,000 7,971E-03 0,05322647 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 7,971E-03 0,05303432 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 7,971E-03 0,05284354 ! histone methylation GO:0016571 5 5 0,000 7,971E-03 0,05265414 ! DNA methylation GO:0006306 5 5 0,000 7,971E-03 0,05246609 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 7,971E-03 0,05227938 ! T cell lineage commitment GO:0002360 5 5 0,000 7,971E-03 0,05209399 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 7,971E-03 0,05190991 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 7,971E-03 0,05172713 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 7,971E-03 0,05154563 ! intracellular cholesterol transport GO:0032367 5 5 0,000 7,971E-03 0,0513654 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 7,971E-03 0,05118643 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 7,971E-03 0,0510087 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 7,971E-03 0,0508322 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 7,971E-03 0,05065692 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 7,971E-03 0,05048284 ! sterol catabolic process GO:0016127 5 5 0,000 7,971E-03 0,05030995 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 7,971E-03 0,05013824 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 7,971E-03 0,04996771 ! detection of biotic stimulus GO:0009595 5 5 0,000 7,971E-03 0,04979832 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 7,971E-03 0,04963009 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 7,971E-03 0,04946298 ! zymogen activation GO:0031638 5 5 0,000 7,971E-03 0,049297 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 7,971E-03 0,04913212 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 7,971E-03 0,04896835 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 7,971E-03 0,04880567 ! peptidyl-lysine modification GO:0018205 5 5 0,000 7,971E-03 0,04864406 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 7,971E-03 0,04848352 ! peptidyl-histidine modification GO:0018202 5 5 0,000 7,971E-03 0,04832403 ! nucleosome positioning GO:0016584 5 5 0,000 7,971E-03 0,04816559 ! regulation of isotype switching GO:0045191 5 5 0,000 7,971E-03 0,04800819 ! negative regulation of neurological system process GO:0031645 5 5 0,000 7,971E-03 0,04785181 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 7,971E-03 0,04769645 ! glutathione biosynthetic process GO:0006750 5 5 0,000 7,971E-03 0,04754209 ! NADPH regeneration GO:0006740 5 5 0,000 7,971E-03 0,04738873 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 7,971E-03 0,04723635 ! positive regulation of epidermis development GO:0045684 5 5 0,000 7,971E-03 0,04708495 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 7,971E-03 0,04693452 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 7,971E-03 0,04678505 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 7,971E-03 0,04663652 ! sarcomere organization GO:0045214 5 5 0,000 7,971E-03 0,04648894 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 7,971E-03 0,04634229 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 7,971E-03 0,04619656 ! negative regulation of glucose transport GO:0010829 5 5 0,000 7,971E-03 0,04605174 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 7,971E-03 0,04590783 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 7,971E-03 0,04576481 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 7,971E-03 0,04562269 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 7,971E-03 0,04548144 ! spleen development GO:0048536 5 5 0,000 7,971E-03 0,04534107 ! male genitalia development GO:0030539 5 5 0,000 7,971E-03 0,04520155 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 7,971E-03 0,0450629 ! quaternary ammonium group transport GO:0015697 5 5 0,000 7,971E-03 0,04492509 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 7,971E-03 0,04478813 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 7,971E-03 0,04465199 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 7,971E-03 0,04451668 ! removal of superoxide radicals GO:0019430 6 5 0,000 7,971E-03 0,04438219 ! myeloid cell homeostasis GO:0002262 5 5 0,000 7,971E-03 0,04424851 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 7,971E-03 0,04411563 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 7,971E-03 0,04398355 ! ATP catabolic process GO:0006200 5 5 0,000 7,971E-03 0,04385225 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 7,971E-03 0,04372174 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 7,971E-03 0,043592 ! blastocyst formation GO:0001825 5 5 0,000 7,971E-03 0,04346303 ! regulation of fibrinolysis GO:0051917 5 5 0,000 7,971E-03 0,04333482 ! embryonic gut development GO:0048566 5 5 0,000 7,971E-03 0,04320737 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 7,971E-03 0,04308066 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 7,971E-03 0,04295469 ! activation of innate immune response GO:0002218 5 5 0,000 7,971E-03 0,04282946 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 7,971E-03 0,04270496 ! catecholamine transport GO:0051937 5 5 0,000 7,971E-03 0,04258117 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 7,971E-03 0,04245811 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 7,971E-03 0,04233575 ! muscle adaptation GO:0043500 5 5 0,000 7,971E-03 0,0422141 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 7,971E-03 0,04209314 ! embryonic heart tube development GO:0035050 5 5 0,000 7,971E-03 0,04197287 ! cardiac cell differentiation GO:0035051 6 5 0,000 7,971E-03 0,04185329 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 7,971E-03 0,04173439 ! defense response to fungus GO:0050832 5 5 0,000 7,971E-03 0,04161616 ! lysogeny GO:0030069 5 5 0,000 7,971E-03 0,0414986 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 7,971E-03 0,04138171 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 7,971E-03 0,04126546 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 7,971E-03 0,04114987 ! response to nicotine GO:0035094 5 5 0,000 7,971E-03 0,04103493 ! mitochondrion localization GO:0051646 5 5 0,000 7,971E-03 0,04092063 ! nucleus localization GO:0051647 5 5 0,000 7,971E-03 0,04080696 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 7,971E-03 0,04069392 ! heart development GO:0007507 90 87 1,000 8,073E-03 0,04110255 ! male gamete generation GO:0048232 90 88 1,000 8,254E-03 0,04190598 GO:0007283|spermatogenesis, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 8,62E-03 0,04364695 ! negative regulation of cell cycle GO:0045786 92 91 1,000 8,806E-03 0,0444667 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 8,994E-03 0,04529112 ! tissue morphogenesis GO:0048729 94 93 1,000 9,184E-03 0,04612015 ! epidermis development GO:0008544 94 94 1,000 9,375E-03 0,04695372 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 9,558E-03 0,0477393 ! axon extension GO:0048675 7 6 0,000 9,558E-03 0,04761027 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 9,558E-03 0,04748194 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 9,558E-03 0,0473543 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 9,558E-03 0,04722735 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 9,558E-03 0,04710107 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 9,558E-03 0,04697547 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 9,558E-03 0,04685053 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 9,558E-03 0,04672626 ! virus-host interaction GO:0019048 6 6 0,000 9,558E-03 0,04660265 ! regulation of S phase GO:0033261 6 6 0,000 9,558E-03 0,04647968 ! myotube differentiation GO:0014902 6 6 0,000 9,558E-03 0,04635737 ! regulation of B cell proliferation GO:0030888 6 6 0,000 9,558E-03 0,0462357 ! bone remodeling GO:0046849 6 6 0,000 9,558E-03 0,04611466 ! N-glycan processing GO:0006491 6 6 0,000 9,558E-03 0,04599426 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 9,558E-03 0,04587448 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 9,558E-03 0,04575533 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 9,558E-03 0,04563679 ! retina development in camera-type eye GO:0060041 6 6 0,000 9,558E-03 0,04551886 ! RNA methylation GO:0001510 6 6 0,000 9,558E-03 0,04540155 ! cartilage condensation GO:0001502 7 6 0,000 9,558E-03 0,04528483 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 9,558E-03 0,04516872 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 9,558E-03 0,0450532 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 9,558E-03 0,04493827 ! artery development GO:0060840 6 6 0,000 9,558E-03 0,04482392 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 9,558E-03 0,04471015 ! bile acid metabolic process GO:0008206 6 6 0,000 9,558E-03 0,04459696 ! androgen metabolic process GO:0008209 6 6 0,000 9,558E-03 0,04448434 ! estrogen metabolic process GO:0008210 6 6 0,000 9,558E-03 0,04437229 ! limbic system development GO:0021761 7 6 0,000 9,558E-03 0,04426081 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 9,558E-03 0,04414988 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 9,558E-03 0,0440395 ! positive regulation of heart contraction GO:0045823 6 6 0,000 9,558E-03 0,04392968 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 9,558E-03 0,0438204 ! pathogenesis GO:0009405 6 6 0,000 9,558E-03 0,04371166 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 9,558E-03 0,04360347 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 9,558E-03 0,0434958 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 9,558E-03 0,04338867 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 9,558E-03 0,04328207 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 9,558E-03 0,04317598 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 9,558E-03 0,04307042 ! arginine metabolic process GO:0006525 6 6 0,000 9,558E-03 0,04296537 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 9,558E-03 0,04286083 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 9,558E-03 0,0427568 ! glutamate catabolic process GO:0006538 7 6 0,000 9,558E-03 0,04265327 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 9,558E-03 0,04255024 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 9,558E-03 0,04244771 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 9,558E-03 0,04234567 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 9,558E-03 0,04224413 ! ER overload response GO:0006983 6 6 0,000 9,558E-03 0,04214306 ! V(D)J recombination GO:0033151 6 6 0,000 9,558E-03 0,04204248 ! focal adhesion formation GO:0048041 7 6 0,000 9,558E-03 0,04194238 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 9,558E-03 0,04184276 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 9,558E-03 0,0417436 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 9,558E-03 0,04164492 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 9,558E-03 0,0415467 ! regulation of heart rate GO:0002027 6 6 0,000 9,558E-03 0,04144894 ! lipid digestion GO:0044241 6 6 0,000 9,558E-03 0,04135164 ! asymmetric protein localization GO:0008105 6 6 0,000 9,558E-03 0,0412548 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 9,558E-03 0,04115841 ! phagocytosis, engulfment GO:0006911 6 6 0,000 9,558E-03 0,04106247 ! Rac protein signal transduction GO:0016601 6 6 0,000 9,558E-03 0,04096698 ! regulation of vascular permeability GO:0043114 6 6 0,000 9,558E-03 0,04087193 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 9,558E-03 0,04077732 ! ruffle organization GO:0031529 6 6 0,000 9,558E-03 0,04068314 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 9,558E-03 0,0405894 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 9,558E-03 0,04049609 ! retinoic acid metabolic process GO:0042573 6 6 0,000 9,558E-03 0,04040321 ! neutral amino acid transport GO:0015804 6 6 0,000 9,558E-03 0,04031076 ! L-amino acid transport GO:0015807 6 6 0,000 9,558E-03 0,04021872 ! bone mineralization GO:0030282 6 6 0,000 9,558E-03 0,04012711 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 9,558E-03 0,04003591 ! negative regulation of ossification GO:0030279 6 6 0,000 9,558E-03 0,03994513 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 9,558E-03 0,03985475 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 9,558E-03 0,03976479 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 9,558E-03 0,03967523 ! purine base biosynthetic process GO:0009113 6 6 0,000 9,558E-03 0,03958607 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 9,558E-03 0,03949731 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 9,558E-03 0,03940895 ! regulation of phagocytosis GO:0050764 6 6 0,000 9,558E-03 0,03932098 ! regulation of organ growth GO:0046620 6 6 0,000 9,558E-03 0,03923341 ! regulation of circadian rhythm GO:0042752 6 6 0,000 9,558E-03 0,03914622 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 9,558E-03 0,03905942 ! response to dsRNA GO:0043331 6 6 0,000 9,558E-03 0,03897301 ! DNA unwinding during replication GO:0006268 6 6 0,000 9,558E-03 0,03888698 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 9,558E-03 0,03880132 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 9,558E-03 0,03871605 ! genitalia development GO:0048806 6 6 0,000 9,558E-03 0,03863114 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 9,558E-03 0,03854661 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 9,558E-03 0,03846245 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 9,558E-03 0,03837865 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 9,558E-03 0,03829522 ! multicellular organismal aging GO:0010259 6 6 0,000 9,558E-03 0,03821215 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 9,558E-03 0,03812944 ! erythrocyte development GO:0048821 6 6 0,000 9,558E-03 0,03804709 ! renal water homeostasis GO:0003091 6 6 0,000 9,558E-03 0,03796509 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 9,558E-03 0,03788344 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 9,558E-03 0,03780215 ! ribosome assembly GO:0042255 6 6 0,000 9,558E-03 0,0377212 ! diencephalon development GO:0021536 6 6 0,000 9,558E-03 0,0376406 ! fucose catabolic process GO:0019317 6 6 0,000 9,558E-03 0,03756034 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 9,558E-03 0,03748043 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 9,558E-03 0,03740085 ! regulation of lipid transport GO:0032368 6 6 0,000 9,558E-03 0,03732161 ! regulation of cell division GO:0051302 6 6 0,000 9,558E-03 0,03724271 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 9,558E-03 0,03716414 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 9,558E-03 0,0370859 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 9,558E-03 0,03700798 ! salivary gland morphogenesis GO:0007435 6 6 0,000 9,558E-03 0,0369304 ! neuroblast proliferation GO:0007405 6 6 0,000 9,558E-03 0,03685314 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 9,558E-03 0,0367762 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 9,558E-03 0,03669958 ! regulation of glucose transport GO:0010827 6 6 0,000 9,558E-03 0,03662329 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 9,558E-03 0,0365473 ! methionine biosynthetic process GO:0009086 6 6 0,000 9,558E-03 0,03647164 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 9,558E-03 0,03639628 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 9,558E-03 0,03632124 ! thymus development GO:0048538 6 6 0,000 9,558E-03 0,0362465 ! lymph node development GO:0048535 6 6 0,000 9,558E-03 0,03617208 ! organic cation transport GO:0015695 6 6 0,000 9,558E-03 0,03609795 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 9,558E-03 0,03602413 ! regulation of RNA splicing GO:0043484 6 6 0,000 9,558E-03 0,03595061 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 9,558E-03 0,03587739 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 9,558E-03 0,03580447 ! sperm-egg recognition GO:0035036 7 6 0,000 9,558E-03 0,03573185 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 9,558E-03 0,03565952 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 9,558E-03 0,03558748 ! alditol metabolic process GO:0019400 6 6 0,000 9,558E-03 0,03551573 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 9,558E-03 0,03544427 ! regulation of amino acid transport GO:0051955 6 6 0,000 9,558E-03 0,03537309 ! maternal placenta development GO:0001893 6 6 0,000 9,558E-03 0,03530221 ! regulation of embryonic development GO:0045995 6 6 0,000 9,558E-03 0,0352316 ! negative regulation of immune effector process GO:0002698 6 6 0,000 9,558E-03 0,03516128 ! localization within membrane GO:0051668 6 6 0,000 9,558E-03 0,03509124 ! regulation of cell growth GO:0001558 97 96 1,000 9,764E-03 0,0357747 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,0101593 0,03714998 ! ectoderm development GO:0007398 99 99 1,000 0,01035973 0,03780788 ! response to hormone stimulus GO:0009725 102 100 1,000 0,01056193 0,03846964 ! muscle organ development GO:0007517 102 100 1,000 0,01056193 0,03839376 ! respiratory burst GO:0045730 7 7 0,000 0,01114316 0,04042685 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,01114316 0,04034743 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,01114316 0,04026831 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,01114316 0,04018951 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,01114316 0,04011102 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,01114316 0,04003283 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,01114316 0,03995494 ! regulation of chemokine production GO:0032642 7 7 0,000 0,01114316 0,03987736 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,01114316 0,03980008 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,01114316 0,0397231 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,01114316 0,03964641 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,01114316 0,03957002 ! gene silencing by RNA GO:0031047 7 7 0,000 0,01114316 0,03949392 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,01114316 0,03941812 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,01114316 0,03934261 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,01114316 0,03926738 ! axis specification GO:0009798 7 7 0,000 0,01114316 0,03919244 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,01114316 0,03911779 ! visual behavior GO:0007632 7 7 0,000 0,01114316 0,03904342 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,01114316 0,03896934 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,01114316 0,03889553 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,01114316 0,038822 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,01114316 0,03874875 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,01114316 0,03867578 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,01114316 0,03860308 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,01114316 0,03853066 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,01114316 0,0384585 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,01114316 0,03838662 ! digestive system development GO:0055123 7 7 0,000 0,01114316 0,038315 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,01114316 0,03824365 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,01114316 0,03817257 ! protein targeting to ER GO:0045047 8 7 0,000 0,01114316 0,03810174 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,01114316 0,03803119 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,01114316 0,03796089 ! endoderm development GO:0007492 7 7 0,000 0,01114316 0,03789085 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,01114316 0,03782107 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,01114316 0,03775154 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,01114316 0,03768228 ! response to hexose stimulus GO:0009746 7 7 0,000 0,01114316 0,03761326 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,01114316 0,0375445 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,01114316 0,03747599 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,01114316 0,03740772 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,01114316 0,03733971 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,01114316 0,03727194 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,01114316 0,03720442 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,01114316 0,03713714 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,01114316 0,03707011 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,01114316 0,03700332 ! response to X-ray GO:0010165 7 7 0,000 0,01114316 0,03693676 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,01114316 0,03687045 ! UV protection GO:0009650 7 7 0,000 0,01114316 0,03680437 ! DNA integration GO:0015074 7 7 0,000 0,01114316 0,03673853 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,01114316 0,03667293 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,01114316 0,03660756 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,01114316 0,03654242 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,01114316 0,03647751 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,01114316 0,03641284 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,01114316 0,03634839 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,01114316 0,03628417 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,01114316 0,03622018 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,01114316 0,03615641 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,01114316 0,03609286 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,01114316 0,03602954 ! axon cargo transport GO:0008088 7 7 0,000 0,01114316 0,03596645 ! eating behavior GO:0042755 7 7 0,000 0,01114316 0,03590357 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,01114316 0,03584091 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,01114316 0,03577847 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,01114316 0,03571624 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,01114316 0,03565424 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,01114316 0,03559244 ! cranial nerve development GO:0021545 7 7 0,000 0,01114316 0,03553087 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,01114316 0,0354695 ! induction of an organ GO:0001759 7 7 0,000 0,01114316 0,03540835 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,01114316 0,0353474 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,01114316 0,03528667 ! autonomic nervous system development GO:0048483 7 7 0,000 0,01114316 0,03522614 ! intracellular lipid transport GO:0032365 7 7 0,000 0,01114316 0,03516582 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,01114316 0,03510571 ! platelet activation GO:0030168 8 7 0,000 0,01114316 0,0350458 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,01114316 0,0349861 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,01114316 0,0349266 ! natural killer cell activation GO:0030101 7 7 0,000 0,01114316 0,0348673 ! response to gamma radiation GO:0010332 8 7 0,000 0,01114316 0,0348082 ! NADP metabolic process GO:0006739 7 7 0,000 0,01114316 0,03474931 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,01114316 0,03469061 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,01114316 0,03463211 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,01114316 0,0345738 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,01114316 0,0345157 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,01114316 0,03445779 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,01114316 0,03440007 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,01114316 0,03434254 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,01114316 0,03428521 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,01114316 0,03422807 ! cell-cell recognition GO:0009988 8 7 0,000 0,01114316 0,03417112 ! hormone catabolic process GO:0042447 7 7 0,000 0,01114316 0,03411435 ! dopamine metabolic process GO:0042417 7 7 0,000 0,01114316 0,03405778 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,01114316 0,03400139 ! oxygen transport GO:0015671 7 7 0,000 0,01114316 0,03394519 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,01114316 0,03388918 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,01114316 0,03383334 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,01114316 0,0337777 ! regulation of axon extension GO:0030516 7 7 0,000 0,01114316 0,03372223 ! cell killing GO:0001906 7 7 0,000 0,01114316 0,03366695 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,01114316 0,03361185 ! adult feeding behavior GO:0008343 7 7 0,000 0,01114316 0,03355693 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,01114316 0,03350219 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,01114316 0,03344762 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,01114316 0,03339324 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,01114316 0,03333903 ! response to cold GO:0009409 7 7 0,000 0,01114316 0,03328499 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,01272579 0,03795086 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,01272579 0,03788955 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,01272579 0,03782844 ! positive regulation of translation GO:0045727 8 8 0,000 0,01272579 0,03776752 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,01272579 0,0377068 ! superoxide anion generation GO:0042554 8 8 0,000 0,01272579 0,03764628 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,01272579 0,03758595 ! cGMP metabolic process GO:0046068 8 8 0,000 0,01272579 0,03752581 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,01272579 0,03746586 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,01272579 0,03740611 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,01272579 0,03734654 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,01272579 0,03728717 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,01272579 0,03722798 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,01272579 0,03716899 ! zinc ion transport GO:0006829 8 8 0,000 0,01272579 0,03711017 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,01272579 0,03705155 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,01272579 0,03699311 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,01272579 0,03693485 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,01272579 0,03687678 ! lipid localization GO:0010876 8 8 0,000 0,01272579 0,03681888 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,01272579 0,03676118 ! response to cAMP GO:0051591 8 8 0,000 0,01272579 0,03670365 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,01272579 0,0366463 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,01272579 0,03658913 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,01272579 0,03653213 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,01272579 0,03647532 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,01272579 0,03641868 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,01272579 0,03636222 ! sensory perception of taste GO:0050909 8 8 0,000 0,01272579 0,03630593 ! organelle fusion GO:0048284 8 8 0,000 0,01272579 0,03624981 ! pancreas development GO:0031016 8 8 0,000 0,01272579 0,03619387 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,01272579 0,0361381 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,01272579 0,03608251 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,01272579 0,03602708 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,01272579 0,03597182 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,01272579 0,03591674 ! sperm motility GO:0030317 8 8 0,000 0,01272579 0,03586182 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,01272579 0,03580707 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,01272579 0,03575248 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,01272579 0,03569807 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,01272579 0,03564381 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,01272579 0,03558973 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01272579 0,0355358 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,01272579 0,03548204 ! Golgi organization GO:0007030 8 8 0,000 0,01272579 0,03542844 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,01272579 0,03537501 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,01272579 0,03532173 ! fructose metabolic process GO:0006000 8 8 0,000 0,01272579 0,03526862 ! mannose metabolic process GO:0006013 9 8 0,000 0,01272579 0,03521566 ! NAD metabolic process GO:0019674 8 8 0,000 0,01272579 0,03516286 ! sex determination GO:0007530 8 8 0,000 0,01272579 0,03511022 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,01272579 0,03505774 ! plasma membrane fusion GO:0045026 8 8 0,000 0,01272579 0,03500542 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,01272579 0,03495325 ! response to fungus GO:0009620 8 8 0,000 0,01272579 0,03490123 ! stem cell differentiation GO:0048863 8 8 0,000 0,01272579 0,03484938 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,01272579 0,03479767 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,01272579 0,03474612 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,01272579 0,03469472 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,01272579 0,03464347 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01272579 0,03459237 ! regulation of vasodilation GO:0042312 8 8 0,000 0,01272579 0,03454143 ! vasoconstriction GO:0042310 8 8 0,000 0,01272579 0,03449063 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,01272579 0,03443998 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,01272579 0,03438949 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,01272579 0,03433914 ! sensory perception of pain GO:0019233 8 8 0,000 0,01272579 0,03428893 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,01272579 0,03423888 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,01272579 0,03418896 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,01272579 0,0341392 ! chromatin silencing GO:0006342 8 8 0,000 0,01272579 0,03408958 ! tissue regeneration GO:0042246 8 8 0,000 0,01272579 0,0340401 ! salivary gland development GO:0007431 8 8 0,000 0,01272579 0,03399077 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,01272579 0,03394158 ! T cell homeostasis GO:0043029 8 8 0,000 0,01272579 0,03389253 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,01272579 0,03384362 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,01272579 0,03379486 ! water homeostasis GO:0030104 8 8 0,000 0,01272579 0,03374623 ! cofactor transport GO:0051181 8 8 0,000 0,01272579 0,03369774 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,01272579 0,0336494 ! acid secretion GO:0046717 8 8 0,000 0,01272579 0,03360119 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,01272579 0,03355312 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,01272579 0,03350519 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,01272579 0,03345739 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,01272579 0,03340973 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,01272579 0,0333622 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,01272579 0,03331481 ! regulation of RNA stability GO:0043487 8 8 0,000 0,01272579 0,03326756 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,01272579 0,03322044 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,01272579 0,03317345 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,01272579 0,0331266 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,01272579 0,03307987 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,01272579 0,03303328 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,01272579 0,03298682 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,01272579 0,03294049 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,01272579 0,03289429 ! developmental induction GO:0031128 8 8 0,000 0,01272579 0,03284822 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,01272579 0,03280228 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,01272579 0,03275647 ! actin filament polymerization GO:0030041 9 8 0,000 0,01272579 0,03271078 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,01272579 0,03266522 ! peptide hormone processing GO:0016486 8 8 0,000 0,01272579 0,03261979 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,01272579 0,03257449 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,01272579 0,03252931 ! lactation GO:0007595 10 9 0,000 0,01430612 0,03651825 ! embryonic pattern specification GO:0009880 10 9 0,000 0,01430612 0,03646774 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,01430612 0,03641737 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,01430612 0,03636714 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,01430612 0,03631705 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,01430612 0,03626709 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,01430612 0,03621727 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,01430612 0,03616759 ! viral genome replication GO:0019079 9 9 0,000 0,01430612 0,03611805 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,01430612 0,03606864 ! copper ion transport GO:0006825 9 9 0,000 0,01430612 0,03601936 ! lipid phosphorylation GO:0046834 9 9 0,000 0,01430612 0,03597022 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,01430612 0,03592122 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,01430612 0,03587235 ! RNA polyadenylation GO:0043631 9 9 0,000 0,01430612 0,03582361 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,01430612 0,035775 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,01430612 0,03572652 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,01430612 0,03567818 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,01430612 0,03562997 ! phospholipid efflux GO:0033700 9 9 0,000 0,01430612 0,03558188 ! response to alkaloid GO:0043279 10 9 0,000 0,01430612 0,03553393 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,01430612 0,0354861 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,01430612 0,03543841 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,01430612 0,03539084 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,01430612 0,0353434 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,01430612 0,03529608 ! response to ethanol GO:0045471 9 9 0,000 0,01430612 0,0352489 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,01430612 0,03520184 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,01430612 0,0351549 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,01430612 0,03510809 ! methionine metabolic process GO:0006555 9 9 0,000 0,01430612 0,0350614 ! glutamine metabolic process GO:0006541 9 9 0,000 0,01430612 0,03501484 ! cerebral cortex development GO:0021987 9 9 0,000 0,01430612 0,0349684 ! response to osmotic stress GO:0006970 9 9 0,000 0,01430612 0,03492209 ! pigmentation during development GO:0048066 9 9 0,000 0,01430612 0,03487589 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,01430612 0,03482982 ! central nervous system neuron development GO:0021954 10 9 0,000 0,01430612 0,03478387 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,01430612 0,03473804 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,01430612 0,03469234 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,01430612 0,03464675 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,01430612 0,03460128 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,01430612 0,03455593 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,01430612 0,0345107 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,01430612 0,03446559 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,01430612 0,03442059 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,01430612 0,03437572 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,01430612 0,03433096 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,01430612 0,03428631 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,01430612 0,03424179 ! DNA replication initiation GO:0006270 9 9 0,000 0,01430612 0,03419737 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,01430612 0,03415308 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,01430612 0,03410889 ! regulation of cellular pH GO:0030641 9 9 0,000 0,01430612 0,03406483 ! histone acetylation GO:0016573 9 9 0,000 0,01430612 0,03402087 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,01430612 0,03397703 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,01430612 0,0339333 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,01430612 0,03388968 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,01430612 0,03384618 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,01430612 0,03380279 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,01430612 0,03375951 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,01430612 0,03371634 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,01430612 0,03367328 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,01430612 0,03363033 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,01430612 0,03358748 ! collagen catabolic process GO:0030574 9 9 0,000 0,01430612 0,03354475 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,01430612 0,03350213 ! purine base metabolic process GO:0006144 9 9 0,000 0,01430612 0,03345961 ! gas transport GO:0015669 9 9 0,000 0,01430612 0,03341721 ! cholesterol efflux GO:0033344 9 9 0,000 0,01430612 0,0333749 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,01430612 0,03333271 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,01430612 0,03329062 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,01430612 0,03324864 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,01430612 0,03320677 ! defense response to virus GO:0051607 9 9 0,000 0,01430612 0,033165 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,01430612 0,03312334 ! actin filament-based movement GO:0030048 9 9 0,000 0,01430612 0,03308178 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,01430612 0,03304032 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01588415 0,0366389 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01588415 0,0365931 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01588415 0,03654742 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,01588415 0,03650185 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01588415 0,03645639 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01588415 0,03641105 ! neuron maturation GO:0042551 10 10 0,000 0,01588415 0,03636581 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01588415 0,0363207 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01588415 0,03627569 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01588415 0,03623079 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01588415 0,03618601 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01588415 0,03614133 ! hormone secretion GO:0046879 10 10 0,000 0,01588415 0,03609677 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01588415 0,03605232 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01588415 0,03600797 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,01588415 0,03596374 ! inositol metabolic process GO:0006020 10 10 0,000 0,01588415 0,03591961 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01588415 0,03587559 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01588415 0,03583168 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01588415 0,03578787 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01588415 0,03574418 ! glial cell development GO:0021782 10 10 0,000 0,01588415 0,03570059 ! phototransduction GO:0007602 11 10 0,000 0,01588415 0,0356571 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01588415 0,03561372 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01588415 0,03557045 ! fat cell differentiation GO:0045444 10 10 0,000 0,01588415 0,03552728 ! myoblast differentiation GO:0045445 10 10 0,000 0,01588415 0,03548422 ! centrosome cycle GO:0007098 10 10 0,000 0,01588415 0,03544126 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01588415 0,03539841 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01588415 0,03535565 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01588415 0,035313 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01588415 0,03527046 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01588415 0,03522802 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,01588415 0,03518567 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01588415 0,03514343 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01588415 0,0351013 ! plasma membrane organization GO:0007009 10 10 0,000 0,01588415 0,03505926 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01588415 0,03501732 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01588415 0,03497549 ! lysosomal transport GO:0007041 10 10 0,000 0,01588415 0,03493375 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01588415 0,03489211 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01588415 0,03485057 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,01588415 0,03480913 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,01588415 0,03476779 ! exocrine system development GO:0035272 10 10 0,000 0,01588415 0,03472655 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01588415 0,0346854 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01588415 0,03464436 ! embryo implantation GO:0007566 11 10 0,000 0,01588415 0,03460341 ! regulation of protein binding GO:0043393 11 10 0,000 0,01588415 0,03456255 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01588415 0,03452179 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01588415 0,03448113 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,01588415 0,03444057 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01588415 0,0344001 ! protein export from nucleus GO:0006611 10 10 0,000 0,01588415 0,03435972 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01588415 0,03431944 ! cytolysis GO:0019835 10 10 0,000 0,01588415 0,03427925 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01588415 0,03423916 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01588415 0,03419916 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01588415 0,03415925 ! histone deacetylation GO:0016575 10 10 0,000 0,01588415 0,03411944 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01588415 0,03407972 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01588415 0,03404009 ! gland morphogenesis GO:0022612 10 10 0,000 0,01588415 0,03400056 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01588415 0,03396111 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01588415 0,03392176 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01588415 0,0338825 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01588415 0,03384333 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,01588415 0,03380425 ! regulation of epidermis development GO:0045682 10 10 0,000 0,01588415 0,03376526 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01588415 0,03372636 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,01588415 0,03368755 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01588415 0,03364883 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01588415 0,0336102 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01588415 0,03357165 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01588415 0,0335332 ! nerve development GO:0021675 10 10 0,000 0,01588415 0,03349483 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,01588415 0,03345655 ! gut development GO:0048565 10 10 0,000 0,01588415 0,03341836 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01588415 0,03338025 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,01588415 0,03334223 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01588415 0,0333043 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01588415 0,03326646 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01588415 0,0332287 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01588415 0,03319102 ! protein stabilization GO:0050821 10 10 0,000 0,01588415 0,03315343 ! protein secretion GO:0009306 11 11 0,000 0,01745988 0,03640108 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01745988 0,03635995 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01745988 0,03631891 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01745988 0,03627796 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01745988 0,03623711 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01745988 0,03619635 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,01745988 0,03615568 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01745988 0,0361151 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01745988 0,03607461 ! signal complex assembly GO:0007172 11 11 0,000 0,01745988 0,03603421 ! microtubule-based transport GO:0010970 11 11 0,000 0,01745988 0,03599391 ! endothelial cell migration GO:0043542 11 11 0,000 0,01745988 0,03595369 ! peroxisomal transport GO:0043574 11 11 0,000 0,01745988 0,03591356 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01745988 0,03587353 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,01745988 0,03583358 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01745988 0,03579372 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01745988 0,03575395 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01745988 0,03571427 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01745988 0,03567467 ! T cell proliferation GO:0042098 11 11 0,000 0,01745988 0,03563516 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01745988 0,03559575 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01745988 0,03555641 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,01745988 0,03551717 ! spinal cord development GO:0021510 11 11 0,000 0,01745988 0,03547801 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01745988 0,03543894 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01745988 0,03539995 ! cellular response to starvation GO:0009267 11 11 0,000 0,01745988 0,03536105 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01745988 0,03532223 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,01745988 0,0352835 ! digestive system process GO:0022600 11 11 0,000 0,01745988 0,03524486 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01745988 0,0352063 ! fucose metabolic process GO:0006004 11 11 0,000 0,01745988 0,03516782 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,01745988 0,03512943 ! monoamine transport GO:0015844 11 11 0,000 0,01745988 0,03509112 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01745988 0,03505289 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01745988 0,03501475 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01745988 0,03497669 ! body fluid secretion GO:0007589 11 11 0,000 0,01745988 0,03493871 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01745988 0,03490082 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,01745988 0,03486301 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01745988 0,03482527 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01745988 0,03478763 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01745988 0,03475006 ! membrane depolarization GO:0051899 11 11 0,000 0,01745988 0,03471257 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01745988 0,03467517 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01745988 0,03463784 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,01745988 0,0346006 ! oogenesis GO:0048477 11 11 0,000 0,01745988 0,03456343 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01745988 0,03452635 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01745988 0,03448934 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,01745988 0,03445241 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,01745988 0,03441557 ! muscle maintenance GO:0046716 12 11 0,000 0,01745988 0,0343788 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01745988 0,03434211 ! hindbrain development GO:0030902 11 11 0,000 0,01745988 0,03430549 ! steroid catabolic process GO:0006706 11 11 0,000 0,01745988 0,03426896 ! endocrine process GO:0050886 11 11 0,000 0,01745988 0,0342325 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01745988 0,03419613 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01745988 0,03415982 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01745988 0,0341236 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,01745988 0,03408745 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01745988 0,03405138 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,01903331 0,03708076 ! translational initiation GO:0006413 12 12 0,000 0,01903331 0,0370416 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,01903331 0,03700253 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,01903331 0,03696354 ! initiation of viral infection GO:0019059 12 12 0,000 0,01903331 0,03692463 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,01903331 0,0368858 ! iron ion transport GO:0006826 13 12 0,000 0,01903331 0,03684706 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,01903331 0,03680839 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,01903331 0,03676981 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,01903331 0,03673131 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,01903331 0,03669289 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,01903331 0,03665454 ! collagen metabolic process GO:0032963 12 12 0,000 0,01903331 0,03661628 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,01903331 0,0365781 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,01903331 0,03654 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,01903331 0,03650198 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,01903331 0,03646403 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,01903331 0,03642617 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,01903331 0,03638838 GO:0042744|hydrogen peroxide catabolic process, ! microtubule organizing center organization GO:0031023 12 12 0,000 0,01903331 0,03635067 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,01903331 0,03631304 ! retinoid metabolic process GO:0001523 12 12 0,000 0,01903331 0,03627549 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,01903331 0,03623802 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,01903331 0,03620062 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,01903331 0,0361633 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,01903331 0,03612605 ! acute-phase response GO:0006953 12 12 0,000 0,01903331 0,03608889 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01903331 0,0360518 ! vacuolar transport GO:0007034 12 12 0,000 0,01903331 0,03601478 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,01903331 0,03597785 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,01903331 0,03594098 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,01903331 0,0359042 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,01903331 0,03586748 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,01903331 0,03583085 ! male gonad development GO:0008584 12 12 0,000 0,01903331 0,03579428 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,01903331 0,0357578 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,01903331 0,03572138 ! renal system process GO:0003014 12 12 0,000 0,01903331 0,03568504 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,01903331 0,03564878 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,01903331 0,03561259 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,01903331 0,03557647 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,01903331 0,03554042 ! pallium development GO:0021543 13 12 0,000 0,01903331 0,03550445 ! cell fate determination GO:0001709 12 12 0,000 0,01903331 0,03546855 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,01903331 0,03543273 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,01903331 0,03539697 ! somitogenesis GO:0001756 13 12 0,000 0,01903331 0,03536129 ! G1 phase GO:0051318 13 12 0,000 0,01903331 0,03532568 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,01903331 0,03529014 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,01903331 0,03525467 ! detection of light stimulus GO:0009583 13 12 0,000 0,01903331 0,03521928 ! synaptogenesis GO:0007416 12 12 0,000 0,01903331 0,03518395 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,01903331 0,0351487 ! hormone transport GO:0009914 12 12 0,000 0,01903331 0,03511351 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,01903331 0,0350784 ! heme biosynthetic process GO:0006783 12 12 0,000 0,01903331 0,03504336 ! spermatid differentiation GO:0048515 13 12 0,000 0,01903331 0,03500838 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,01903331 0,03497348 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,01903331 0,03493864 ! neural tube closure GO:0001843 13 12 0,000 0,01903331 0,03490388 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,01903331 0,03486918 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,01903331 0,03483456 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,01903331 0,0348 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,02060446 0,0376353 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,02060446 0,03759804 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,02060446 0,03756085 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,02060446 0,03752374 ! phenol metabolic process GO:0018958 13 13 0,000 0,02060446 0,03748669 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,02060446 0,03744973 ! gluconeogenesis GO:0006094 13 13 0,000 0,02060446 0,03741283 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,02060446 0,03737601 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,02060446 0,03733925 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,02060446 0,03730258 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,02060446 0,03726597 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,02060446 0,03722943 ! regeneration GO:0031099 13 13 0,000 0,02060446 0,03719297 ! keratinization GO:0031424 13 13 0,000 0,02060446 0,03715658 ! post-embryonic development GO:0009791 14 13 0,000 0,02060446 0,03712026 ! patterning of blood vessels GO:0001569 13 13 0,000 0,02060446 0,03708401 ! vasculogenesis GO:0001570 13 13 0,000 0,02060446 0,03704783 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,02060446 0,03701172 ! regulation of innate immune response GO:0045088 13 13 0,000 0,02060446 0,03697568 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,02060446 0,03693971 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,02060446 0,03690381 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,02060446 0,03686798 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,02060446 0,03683222 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,02060446 0,03679653 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,02060446 0,03676091 ! autophagy GO:0006914 13 13 0,000 0,02060446 0,03672536 ! receptor metabolic process GO:0043112 14 13 0,000 0,02060446 0,03668988 ! actin filament bundle formation GO:0051017 13 13 0,000 0,02060446 0,03665446 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,02060446 0,03661911 ! ureteric bud development GO:0001657 13 13 0,000 0,02060446 0,03658384 ! cell aging GO:0007569 13 13 0,000 0,02060446 0,03654863 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,02060446 0,03651348 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,02060446 0,03647841 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,02060446 0,0364434 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,02060446 0,03640846 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,02060446 0,03637358 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,02060446 0,03633878 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,02060446 0,03630404 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,02060446 0,03626936 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,02060446 0,03623475 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,02060446 0,03620021 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,02060446 0,03616574 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,02060446 0,03613132 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,02060446 0,03609698 ! vasodilation GO:0042311 14 13 0,000 0,02060446 0,0360627 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,02060446 0,03602848 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,02060446 0,03599433 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,02060446 0,03596025 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,02060446 0,03592623 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,02060446 0,03589227 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,02060446 0,03585838 ! immunoglobulin production GO:0002377 13 13 0,000 0,02060446 0,03582455 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,02060446 0,03579078 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,02060446 0,03575708 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,02060446 0,03572344 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,02060446 0,03568987 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,02060446 0,03565636 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,02060446 0,03562291 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,02060446 0,03558952 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,02060446 0,0355562 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,02060446 0,03552294 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,02060446 0,03548974 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,02060446 0,0354566 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,02060446 0,03542353 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,02060446 0,03539051 ! blastocyst development GO:0001824 13 13 0,000 0,02060446 0,03535756 ! telomere organization GO:0032200 13 13 0,000 0,02060446 0,03532467 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,02060446 0,03529184 ! regulation of amine transport GO:0051952 13 13 0,000 0,02060446 0,03525907 ! tissue homeostasis GO:0001894 13 13 0,000 0,02060446 0,03522637 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,02060446 0,03519372 ! protein tetramerization GO:0051262 13 13 0,000 0,02060446 0,03516113 ! neuron fate commitment GO:0048663 14 14 0,000 0,02217332 0,03780336 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,02217332 0,03776842 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,02217332 0,03773354 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,02217332 0,03769873 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,02217332 0,03766399 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,02217332 0,03762931 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,02217332 0,03759469 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,02217332 0,03756014 ! protein amino acid acylation GO:0043543 14 14 0,000 0,02217332 0,03752565 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,02217332 0,03749122 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,02217332 0,03745685 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,02217332 0,03742255 ! vesicle docking GO:0048278 14 14 0,000 0,02217332 0,03738831 ! superoxide metabolic process GO:0006801 15 14 0,000 0,02217332 0,03735414 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,02217332 0,03732003 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,02217332 0,03728597 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,02217332 0,03725199 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,02217332 0,03721806 ! hair cycle GO:0042633 14 14 0,000 0,02217332 0,03718419 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,02217332 0,03715039 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,02217332 0,03711665 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,02217332 0,03708297 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,02217332 0,03704935 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,02217332 0,03701579 ! lysosome organization GO:0007040 14 14 0,000 0,02217332 0,03698229 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,02217332 0,03694885 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,02217332 0,03691547 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,02217332 0,03688216 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,02217332 0,0368489 ! peptide cross-linking GO:0018149 14 14 0,000 0,02217332 0,0368157 ! regulation of behavior GO:0050795 14 14 0,000 0,02217332 0,03678256 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,02217332 0,03674949 ! base-excision repair GO:0006284 14 14 0,000 0,02217332 0,03671647 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,02217332 0,03668351 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,02217332 0,03665061 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,02217332 0,03661777 ! formation of primary germ layer GO:0001704 14 14 0,000 0,02217332 0,03658498 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,02217332 0,03655226 ! collagen fibril organization GO:0030199 14 14 0,000 0,02217332 0,0365196 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,02217332 0,03648699 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,02217332 0,03645444 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,02217332 0,03642195 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,02217332 0,03638952 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,02217332 0,03635714 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,02217332 0,03632482 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,02217332 0,03629256 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,02217332 0,03626036 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,02217332 0,03622822 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,02373989 0,03875343 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,02373989 0,03871914 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,02373989 0,0386849 ! positive regulation of ossification GO:0045778 15 15 0,000 0,02373989 0,03865073 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,02373989 0,03861661 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,02373989 0,03858256 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,02373989 0,03854857 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,02373989 0,03851463 ! response to vitamin GO:0033273 15 15 0,000 0,02373989 0,03848076 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,02373989 0,03844694 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,02373989 0,03841319 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,02373989 0,03837949 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,02373989 0,03834586 ! ovarian follicle development GO:0001541 15 15 0,000 0,02373989 0,03831228 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,02373989 0,03827876 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,02373989 0,0382453 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,02373989 0,0382119 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,02373989 0,03817855 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,02373989 0,03814527 ! heme metabolic process GO:0042168 15 15 0,000 0,02373989 0,03811204 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,02373989 0,03807887 ! chromosome condensation GO:0030261 15 15 0,000 0,02373989 0,03804576 ! response to starvation GO:0042594 15 15 0,000 0,02373989 0,0380127 ! response to ionizing radiation GO:0010212 16 15 0,000 0,02373989 0,03797971 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,02373989 0,03794677 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,02373989 0,03791388 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,02373989 0,03788106 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,02373989 0,03784829 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,02373989 0,03781558 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,02373989 0,03778292 ! phospholipid transport GO:0015914 15 15 0,000 0,02373989 0,03775032 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,02373989 0,03771778 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,02373989 0,03768529 ! glutathione metabolic process GO:0006749 16 15 0,000 0,02373989 0,03765286 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,02373989 0,03762048 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,02373989 0,03758816 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,02373989 0,0375559 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,02373989 0,03752369 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,02373989 0,03749154 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,02373989 0,03745944 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,02373989 0,03742739 ! protein homooligomerization GO:0051260 15 15 0,000 0,02373989 0,0373954 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,02373989 0,03736347 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,02530418 0,03979148 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,02530418 0,03975756 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,02530418 0,03972369 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,02530418 0,03968988 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,02530418 0,03965613 ! learning GO:0007612 16 16 0,000 0,02530418 0,03962244 ! circadian rhythm GO:0007623 16 16 0,000 0,02530418 0,0395888 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,02530418 0,03955523 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,02530418 0,03952171 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,02530418 0,03948824 ! vacuole organization GO:0007033 16 16 0,000 0,02530418 0,03945483 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,02530418 0,03942148 ! vesicle targeting GO:0006903 17 16 0,000 0,02530418 0,03938819 ! segmentation GO:0035282 17 16 0,000 0,02530418 0,03935495 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,02530418 0,03932176 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,02530418 0,03928864 ! iron ion homeostasis GO:0055072 16 16 0,000 0,02530418 0,03925557 ! positive regulation of cell development GO:0010720 16 16 0,000 0,02530418 0,03922255 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,02530418 0,03918959 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,02530418 0,03915669 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,02530418 0,03912384 ! cell fate specification GO:0001708 16 16 0,000 0,02530418 0,03909104 ! pentose metabolic process GO:0019321 16 16 0,000 0,02530418 0,0390583 ! fatty acid transport GO:0015908 16 16 0,000 0,02530418 0,03902562 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,02530418 0,03899299 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,02530418 0,03896041 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,02530418 0,03892789 ! cofactor catabolic process GO:0051187 16 16 0,000 0,02530418 0,03889542 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,02530418 0,03886301 ! polyol metabolic process GO:0019751 16 16 0,000 0,02530418 0,03883065 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,02530418 0,03879835 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,02530418 0,03876609 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,02530418 0,0387339 GO:0033013|tetrapyrrole metabolic process, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,02530418 0,03870175 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,02530418 0,03866966 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,02530418 0,03863762 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,02530418 0,03860564 ! regulation of coagulation GO:0050818 17 16 0,000 0,02530418 0,03857371 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,0268662 0,04092099 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,0268662 0,0408872 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,0268662 0,04085347 ! myelination GO:0042552 17 17 0,000 0,0268662 0,04081979 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,0268662 0,04078616 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,0268662 0,04075259 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,0268662 0,04071908 ! leukocyte adhesion GO:0007159 17 17 0,000 0,0268662 0,04068562 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,0268662 0,04065222 ! sensory perception of smell GO:0007608 17 17 0,000 0,0268662 0,04061887 ! glucose transport GO:0015758 17 17 0,000 0,0268662 0,04058557 ! cell junction assembly GO:0034329 18 17 0,000 0,0268662 0,04055234 ! tissue remodeling GO:0048771 17 17 0,000 0,0268662 0,04051915 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,0268662 0,04048602 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,0268662 0,04045294 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,0268662 0,04041992 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,0268662 0,04038695 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,0268662 0,04035404 ! response to toxin GO:0009636 18 17 0,000 0,0268662 0,04032117 ! negative regulation of cell development GO:0010721 18 17 0,000 0,0268662 0,04028837 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,0268662 0,04025561 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,0268662 0,04022291 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,0268662 0,04019026 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,0268662 0,04015767 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,0268662 0,04012512 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,0268662 0,04009263 ! pigmentation GO:0043473 17 17 0,000 0,0268662 0,0400602 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,0268662 0,04002781 ! adult locomotory behavior GO:0008344 17 17 0,000 0,0268662 0,03999548 ! embryonic organ development GO:0048568 17 17 0,000 0,0268662 0,0399632 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,0268662 0,03993097 ! liver development GO:0001889 17 17 0,000 0,0268662 0,03989879 ! gene silencing GO:0016458 17 17 0,000 0,0268662 0,03986667 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,02842593 0,04214722 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,02842593 0,04211334 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,02842593 0,04207951 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,02842593 0,04204574 ! meiosis I GO:0007127 18 18 0,000 0,02842593 0,04201203 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,02842593 0,04197836 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,02842593 0,04194475 ! membrane docking GO:0022406 18 18 0,000 0,02842593 0,0419112 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,02842593 0,04187769 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,02842593 0,04184425 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,02842593 0,04181085 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,02842593 0,04177751 ! hexose transport GO:0008645 18 18 0,000 0,02842593 0,04174422 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,02842593 0,04171098 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,02842593 0,0416778 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,02842593 0,04164467 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,02842593 0,04161159 ! ceramide metabolic process GO:0006672 18 18 0,000 0,02842593 0,04157857 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,02842593 0,0415456 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,02842593 0,04151267 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,02842593 0,04147981 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,02842593 0,04144699 ! B cell differentiation GO:0030183 18 18 0,000 0,02842593 0,04141423 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,02842593 0,04138151 ! ensheathment of neurons GO:0007272 18 18 0,000 0,02842593 0,04134885 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,02842593 0,04131624 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,02842593 0,04128368 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,02842593 0,04125118 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,02842593 0,04121872 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,02842593 0,04118632 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,0299834 0,0434088 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,0299834 0,04337473 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,0299834 0,04334071 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,0299834 0,04330674 ! glial cell differentiation GO:0010001 19 19 0,000 0,0299834 0,04327283 ! regulation of pH GO:0006885 19 19 0,000 0,0299834 0,04323897 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,0299834 0,04320516 ! feeding behavior GO:0007631 19 19 0,000 0,0299834 0,04317141 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,0299834 0,04313771 ! peroxisome organization GO:0007031 19 19 0,000 0,0299834 0,04310406 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,0299834 0,04307046 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,0299834 0,04303692 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,0299834 0,04300342 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,0299834 0,04296999 ! metanephros development GO:0001656 19 19 0,000 0,0299834 0,0429366 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,0299834 0,04290326 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,0299834 0,04286998 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,0299834 0,04283674 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,0299834 0,04280356 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,0299834 0,04277043 ! peripheral nervous system development GO:0007422 19 19 0,000 0,0299834 0,04273736 ! regulation of protein stability GO:0031647 19 19 0,000 0,0299834 0,04270433 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,0299834 0,04267135 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,0299834 0,04263843 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,0299834 0,04260555 ! regulation of cell shape GO:0008360 21 19 0,000 0,0299834 0,04257273 ! placenta development GO:0001890 19 19 0,000 0,0299834 0,04253995 ! response to heat GO:0009408 19 19 0,000 0,0299834 0,04250723 ! vesicle localization GO:0051648 20 19 0,000 0,0299834 0,04247456 ! regulation of muscle development GO:0048634 21 20 0,000 0,03153859 0,04464334 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,03153859 0,04460907 ! negative regulation of binding GO:0051100 21 20 0,000 0,03153859 0,04457486 ! organic ether metabolic process GO:0018904 20 20 0,000 0,03153859 0,04454071 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,03153859 0,0445066 ! nucleus organization GO:0006997 20 20 0,000 0,03153859 0,04447255 ! phagocytosis GO:0006909 21 20 0,000 0,03153859 0,04443855 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,03153859 0,0444046 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,03153859 0,0443707 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,03153859 0,04433686 ! chromatin remodeling GO:0006338 20 20 0,000 0,03153859 0,04430307 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,03153859 0,04426932 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,03153859 0,04423563 ! lipid oxidation GO:0034440 20 20 0,000 0,03153859 0,04420199 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,03153859 0,04416841 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,03153859 0,04413487 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,03153859 0,04410138 ! RNA modification GO:0009451 20 20 0,000 0,03153859 0,04406795 ! single fertilization GO:0007338 21 20 0,000 0,03153859 0,04403456 ! regulation of B cell activation GO:0050864 20 20 0,000 0,03153859 0,04400123 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,03309152 0,04613288 ! mRNA catabolic process GO:0006402 21 21 0,000 0,03309152 0,04609801 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,03309152 0,04606319 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,03309152 0,04602843 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,03309152 0,04599371 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,03309152 0,04595906 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,03309152 0,04592445 ! Notch signaling pathway GO:0007219 22 21 0,000 0,03309152 0,04588989 ! ear morphogenesis GO:0042471 21 21 0,000 0,03309152 0,04585539 ! organic anion transport GO:0015711 21 21 0,000 0,03309152 0,04582094 ! cholesterol transport GO:0030301 21 21 0,000 0,03309152 0,04578654 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,03309152 0,04575219 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,03309152 0,04571789 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,03309152 0,04568364 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,03309152 0,04564945 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,03309152 0,04561531 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,03309152 0,04558122 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,03309152 0,04554717 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,03309152 0,04551318 ! regulation of proteolysis GO:0030162 21 21 0,000 0,03309152 0,04547924 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,03309152 0,04544535 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,03309152 0,04541152 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,03309152 0,04537773 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,03464218 0,0474688 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,03464218 0,04743353 ! sister chromatid segregation GO:0000819 22 22 0,000 0,03464218 0,04739832 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,03464218 0,04736316 ! regulation of ion transport GO:0043269 22 22 0,000 0,03464218 0,04732805 ! odontogenesis GO:0042476 22 22 0,000 0,03464218 0,04729299 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,03464218 0,04725798 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,03464218 0,04722303 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,03464218 0,04718813 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,03464218 0,04715328 ! ovulation cycle process GO:0022602 22 22 0,000 0,03464218 0,04711848 ! spindle organization GO:0007051 22 22 0,000 0,03464218 0,04708373 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,03464218 0,04704903 ! cell chemotaxis GO:0060326 23 22 0,000 0,03464218 0,04701439 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,03464218 0,04697979 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,03464218 0,04694525 ! male sex differentiation GO:0046661 22 22 0,000 0,03464218 0,04691075 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,03464218 0,04687631 ! biopolymer methylation GO:0043414 22 22 0,000 0,03464218 0,04684192 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,03464218 0,04680758 ! detection of external stimulus GO:0009581 23 22 0,000 0,03464218 0,04677329 ! neuron migration GO:0001764 22 22 0,000 0,03464218 0,04673905 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,03464218 0,04670486 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,03464218 0,04667071 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,03464218 0,04663662 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,03464218 0,04660258 ! aerobic respiration GO:0009060 22 22 0,000 0,03464218 0,04656859 ! cytokine production GO:0001816 22 22 0,000 0,03464218 0,04653465 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,03464218 0,04650076 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,03619058 0,04854384 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,03619058 0,04850854 ! viral infectious cycle GO:0019058 23 23 0,000 0,03619058 0,04847329 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,03619058 0,04843808 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,03619058 0,04840293 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,03619058 0,04836783 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,03619058 0,04833278 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,03619058 0,04829778 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,03619058 0,04826284 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,03619058 0,04822794 ! endocrine system development GO:0035270 23 23 0,000 0,03619058 0,04819309 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,03619058 0,0481583 ! female gonad development GO:0008585 23 23 0,000 0,03619058 0,04812355 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,03619058 0,04808885 ! lipid homeostasis GO:0055088 23 23 0,000 0,03619058 0,04805421 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,03619058 0,04801961 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,03619058 0,04798507 ! mitochondrial transport GO:0006839 24 24 0,000 0,03773672 0,04999912 ! regulation of action potential GO:0001508 24 24 0,000 0,03773672 0,04996321 ! gliogenesis GO:0042063 24 24 0,000 0,03773672 0,04992734 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,03773672 0,04989152 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,03773672 0,04985576 ! glucose homeostasis GO:0042593 24 24 0,000 0,03773672 0,04982004 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,03773672 0,04978438 ! T cell differentiation GO:0030217 24 24 0,000 0,03773672 0,04974877 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,03773672 0,04971321 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,03773672 0,0496777 ! ovulation cycle GO:0042698 24 24 0,000 0,03773672 0,04964224 ! fertilization GO:0009566 25 24 0,000 0,03773672 0,04960683 ! maintenance of protein location GO:0045185 25 24 0,000 0,03773672 0,04957148 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,03773672 0,04953617 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,03773672 0,04950091 ! glucan metabolic process GO:0044042 25 24 0,000 0,03773672 0,04946571 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,03928061 0,05145286 ! negative regulation of secretion GO:0051048 26 25 0,000 0,03928061 0,05141631 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,03928061 0,05137982 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,03928061 0,05134338 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,03928061 0,05130699 ! cellular component disassembly GO:0022411 26 25 0,000 0,03928061 0,05127066 ! endosome transport GO:0016197 25 25 0,000 0,03928061 0,05123437 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,03928061 0,05119814 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,03928061 0,05116196 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,03928061 0,05112582 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,03928061 0,05108974 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,03928061 0,05105371 ! excretion GO:0007588 25 25 0,000 0,03928061 0,05101774 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,03928061 0,05098181 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,03928061 0,05094593 ! gastrulation GO:0007369 25 25 0,000 0,03928061 0,0509101 ! heart morphogenesis GO:0003007 25 25 0,000 0,03928061 0,05087433 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,03928061 0,0508386 ! regulation of endocytosis GO:0030100 25 25 0,000 0,03928061 0,05080292 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,03928061 0,0507673 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,03928061 0,05073172 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,03928061 0,0506962 ! positive regulation of binding GO:0051099 27 26 0,000 0,04082225 0,05264899 ! positive regulation of defense response GO:0031349 26 26 0,000 0,04082225 0,05261217 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,04082225 0,0525754 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,04082225 0,05253869 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,04082225 0,05250203 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,04082225 0,05246541 ! cellular defense response GO:0006968 26 26 0,000 0,04082225 0,05242885 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,04082225 0,05239234 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,04082225 0,05235588 ! double-strand break repair GO:0006302 27 26 0,000 0,04082225 0,05231947 ! regulation of protein secretion GO:0050708 26 26 0,000 0,04082225 0,05228312 ! germ cell development GO:0007281 27 26 0,000 0,04082225 0,05224681 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,04082225 0,05221055 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,04082225 0,05217434 ! maintenance of location in cell GO:0051651 27 26 0,000 0,04082225 0,05213819 ! synapse organization GO:0050808 26 26 0,000 0,04082225 0,05210208 ! chloride transport GO:0006821 27 27 0,000 0,04236163 0,05402941 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,04236163 0,05399204 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,04236163 0,05395473 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,04236163 0,05391747 ! learning or memory GO:0007611 28 27 0,000 0,04236163 0,05388026 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,04236163 0,0538431 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,04236163 0,05380599 ! peptide metabolic process GO:0006518 29 27 0,000 0,04236163 0,05376893 ! activation of caspase activity GO:0006919 27 27 0,000 0,04236163 0,05373193 ! inner ear development GO:0048839 27 27 0,000 0,04236163 0,05369497 ! defense response to bacterium GO:0042742 27 27 0,000 0,04236163 0,05365807 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,04236163 0,05362122 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,04236163 0,05358441 ! cell growth GO:0016049 27 27 0,000 0,04236163 0,05354766 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,04389877 0,05545267 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,04389877 0,05541469 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,04389877 0,05537676 ! carbohydrate transport GO:0008643 28 28 0,000 0,04389877 0,05533888 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,04389877 0,05530105 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,04389877 0,05526328 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,04389877 0,05522556 ! histone modification GO:0016570 28 28 0,000 0,04389877 0,05518789 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,04389877 0,05515027 ! developmental growth GO:0048589 28 28 0,000 0,04389877 0,0551127 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,04389877 0,05507518 ! cartilage development GO:0051216 29 28 0,000 0,04389877 0,05503772 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,04543367 0,05692336 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,04543367 0,05688468 ! viral reproductive process GO:0022415 29 29 0,000 0,04543367 0,05684607 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,04543367 0,0568075 ! leukocyte migration GO:0050900 30 29 0,000 0,04543367 0,05676899 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,04543367 0,05673053 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,04543367 0,05669212 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,04543367 0,05665376 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,04543367 0,05661545 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,04543367 0,0565772 ! tRNA processing GO:0008033 29 29 0,000 0,04543367 0,056539 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,04543367 0,05650085 ! covalent chromatin modification GO:0016569 29 29 0,000 0,04543367 0,05646275 ! adult behavior GO:0030534 30 29 0,000 0,04543367 0,0564247 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,04543367 0,0563867 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,04543367 0,05634876 ! response to UV GO:0009411 29 29 0,000 0,04543367 0,05631087 ! transition metal ion transport GO:0000041 31 30 0,000 0,04696633 0,05817133 ! RNA catabolic process GO:0006401 30 30 0,000 0,04696633 0,05813226 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,04696633 0,05809325 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,04696633 0,05805429 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,04696633 0,05801538 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,04696633 0,05797652 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,04696633 0,05793771 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,04696633 0,05789896 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,04696633 0,05786026 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,04696633 0,0578216 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,04696633 0,05778301 ! response to temperature stimulus GO:0009266 30 30 0,000 0,04696633 0,05774446 ! regulation of ossification GO:0030278 30 30 0,000 0,04696633 0,05770596 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,04696633 0,05766752 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,04696633 0,05762912 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,04696633 0,05759078 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,04696633 0,05755249 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,04696633 0,05751425 ! establishment of organelle localization GO:0051656 31 30 0,000 0,04696633 0,05747606 ! regulation of translational initiation GO:0006446 31 31 0,000 0,04849675 0,05930956 ! membrane fusion GO:0006944 31 31 0,000 0,04849675 0,05927023 ! B cell activation GO:0042113 31 31 0,000 0,04849675 0,05923095 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,04849675 0,05919172 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,04849675 0,05915255 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,04849675 0,05911343 ! ion transmembrane transport GO:0034220 31 31 0,000 0,04849675 0,05907436 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,04849675 0,05903534 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,04849675 0,05899637 ! digestion GO:0007586 31 31 0,000 0,04849675 0,05895746 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,04849675 0,05891859 ! regulation of DNA replication GO:0006275 32 31 0,000 0,04849675 0,05887978 ! regulation of heart contraction GO:0008016 31 31 0,000 0,04849675 0,05884102 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,04849675 0,05880231 ! camera-type eye development GO:0043010 31 31 0,000 0,04849675 0,05876365 ! extracellular matrix organization GO:0030198 31 31 0,000 0,04849675 0,05872504 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,04849675 0,05868648 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,04849675 0,05864797 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,04849675 0,05860951 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,04849675 0,0585711 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,05002493 0,06037718 ! cell redox homeostasis GO:0045454 32 32 0,000 0,05002493 0,06033766 ! lipid modification GO:0030258 32 32 0,000 0,05002493 0,0602982 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,05002493 0,06025879 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,05002493 0,06021943 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,05002493 0,06018012 ! cell maturation GO:0048469 32 32 0,000 0,05002493 0,06014087 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,05002493 0,06010166 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,05002493 0,06006251 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,05002493 0,0600234 ! kidney development GO:0001822 32 32 0,000 0,05002493 0,05998435 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,05002493 0,05994535 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,05002493 0,0599064 ! maintenance of location GO:0051235 33 32 0,000 0,05002493 0,0598675 ! negative regulation of cell size GO:0045792 33 33 0,000 0,05155088 0,06165365 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,05155088 0,06161367 ! amino acid transport GO:0006865 33 33 0,000 0,05155088 0,06157374 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,05155088 0,06153386 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,05155088 0,06149403 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,05155088 0,06145426 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,05155088 0,06141453 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,05155088 0,06137486 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,05155088 0,06133524 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,05307461 0,06310742 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,05307461 0,06306673 ! response to metal ion GO:0010038 34 34 0,000 0,05307461 0,0630261 ! ear development GO:0043583 34 34 0,000 0,05307461 0,06298551 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,05307461 0,06294498 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,05307461 0,0629045 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,05307461 0,06286408 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,05307461 0,0628237 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,05307461 0,06278338 ! secondary metabolic process GO:0019748 34 34 0,000 0,05307461 0,06274311 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,05307461 0,06270289 ! detection of stimulus GO:0051606 36 34 0,000 0,05307461 0,06266272 ! acute inflammatory response GO:0002526 35 35 0,000 0,05459611 0,06441781 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,05459611 0,0643766 ! mesoderm development GO:0007498 35 35 0,000 0,05459611 0,06433544 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,05459611 0,06429433 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,05459611 0,06425327 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,05459611 0,06421227 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,05459611 0,06417132 ! inorganic anion transport GO:0015698 35 35 0,000 0,05459611 0,06413042 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,05459611 0,06408957 ! regulation of immune effector process GO:0002697 35 35 0,000 0,05459611 0,06404878 ! hydrogen transport GO:0006818 36 36 0,000 0,05611538 0,06578922 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,05611538 0,06574739 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,05611538 0,06570562 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,05611538 0,06566391 ! regulation of mitosis GO:0007088 37 36 0,000 0,05611538 0,06562224 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,05611538 0,06558063 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,05611538 0,06553907 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,05611538 0,06549756 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,05611538 0,06545611 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,05611538 0,06541471 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,05611538 0,06537336 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,05611538 0,06533206 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,05611538 0,06529081 ! gonad development GO:0008406 36 36 0,000 0,05611538 0,06524962 ! regulation of lipase activity GO:0060191 36 36 0,000 0,05611538 0,06520848 ! activation of immune response GO:0002253 36 36 0,000 0,05611538 0,06516739 ! coagulation GO:0050817 39 36 0,000 0,05611538 0,06512635 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,05763244 0,06684492 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,05763244 0,06680288 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,05763244 0,0667609 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 0,000 0,05763244 0,06671896 ! lung development GO:0030324 38 37 0,000 0,05763244 0,06667708 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,05763244 0,06663525 ! negative regulation of growth GO:0045926 37 37 0,000 0,05763244 0,06659347 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,05763244 0,06655174 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,05763244 0,06651007 ! adaptive immune response GO:0002250 37 37 0,000 0,05763244 0,06646845 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,05914728 0,06817288 ! neurotransmitter transport GO:0006836 40 38 0,000 0,05914728 0,06813027 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,05914728 0,06808772 ! exocytosis GO:0006887 40 38 0,000 0,05914728 0,06804521 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,05914728 0,06800277 ! chromosome segregation GO:0007059 38 38 0,000 0,05914728 0,06796037 ! urogenital system development GO:0001655 38 38 0,000 0,05914728 0,06791803 ! RNA elongation GO:0006354 38 38 0,000 0,05914728 0,06787574 ! meiotic cell cycle GO:0051321 38 38 0,000 0,05914728 0,0678335 ! regulation of neurological system process GO:0031644 38 38 0,000 0,05914728 0,06779131 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,05914728 0,06774918 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,05914728 0,0677071 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,0606599 0,06939553 ! hemostasis GO:0007599 42 39 0,000 0,0606599 0,06935248 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,0606599 0,06930949 ! activation of MAPK activity GO:0000187 39 39 0,000 0,0606599 0,06926654 ! respiratory tube development GO:0030323 40 39 0,000 0,0606599 0,06922365 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,0606599 0,06918082 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,0606599 0,06913803 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,0606599 0,0690953 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,0606599 0,06905263 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,0606599 0,06901 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,0606599 0,06896743 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,0606599 0,06892491 ! respiratory system development GO:0060541 40 39 0,000 0,0606599 0,06888244 ! developmental maturation GO:0021700 39 39 0,000 0,0606599 0,06884003 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,0606599 0,06879766 ! limb development GO:0060173 39 39 0,000 0,0606599 0,06875535 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,0606599 0,06871309 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,0606599 0,06867089 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,06217032 0,07033757 ! DNA catabolic process GO:0006308 41 40 0,000 0,06217032 0,07029441 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,06217032 0,07025131 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,06217032 0,07020827 ! organelle localization GO:0051640 41 40 0,000 0,06217032 0,07016527 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,06367852 0,07182345 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,06367852 0,07177952 ! amine catabolic process GO:0009310 42 41 0,000 0,06367852 0,07173565 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,06367852 0,07169182 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,06367852 0,07164806 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,06367852 0,07160434 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,06518452 0,07325309 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,06518452 0,07320846 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,06518452 0,07316387 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,06518452 0,07311934 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,06518452 0,07307486 ! protein ubiquitination GO:0016567 43 42 0,000 0,06518452 0,07303044 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,06518452 0,07298607 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 0,000 0,06518452 0,07294176 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,06518452 0,0728975 ! reproductive structure development GO:0048608 43 43 0,000 0,06668832 0,07453401 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,06668832 0,07448883 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,06668832 0,07444372 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,06668832 0,07439865 ! humoral immune response GO:0006959 44 44 0,000 0,06818992 0,07602784 ! mRNA transport GO:0051028 44 44 0,000 0,06818992 0,07598187 ! protein import into nucleus GO:0006606 44 44 0,000 0,06818992 0,07593596 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,06818992 0,07589011 ! vitamin metabolic process GO:0006766 44 44 0,000 0,06818992 0,07584431 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,06818992 0,07579857 ! amine biosynthetic process GO:0009309 46 45 0,000 0,06968932 0,07741858 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,06968932 0,07737194 ! regulation of DNA binding GO:0051101 47 45 0,000 0,06968932 0,07732536 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,06968932 0,07727883 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,06968932 0,07723236 ! nuclear import GO:0051170 45 45 0,000 0,06968932 0,07718595 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,06968932 0,07713959 ! protein processing GO:0016485 45 45 0,000 0,06968932 0,07709329 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,07118653 0,07870232 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,07118653 0,07865514 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,07118653 0,07860801 ! regulation of membrane potential GO:0042391 46 46 0,000 0,07118653 0,07856094 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,07268155 0,08016283 ! regulation of blood pressure GO:0008217 48 47 0,000 0,07268155 0,08011489 ! sex differentiation GO:0007548 47 47 0,000 0,07268155 0,080067 ! amine transport GO:0015837 47 47 0,000 0,07268155 0,08001917 ! rhythmic process GO:0048511 47 47 0,000 0,07268155 0,0799714 ! regulation of catabolic process GO:0009894 48 47 0,000 0,07268155 0,07992368 ! calcium ion transport GO:0006816 48 48 0,000 0,07417438 0,08151662 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,07417438 0,08146804 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,07417438 0,08141952 ! protein localization in nucleus GO:0034504 48 48 0,000 0,07417438 0,08137106 ! DNA recombination GO:0006310 48 48 0,000 0,07417438 0,08132265 ! leukocyte differentiation GO:0002521 50 49 0,000 0,07566502 0,08290763 ! ossification GO:0001503 50 49 0,000 0,07566502 0,08285837 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,07566502 0,08280916 ! cell cycle arrest GO:0007050 49 49 0,000 0,07566502 0,08276002 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,07566502 0,08271093 ! divalent metal ion transport GO:0070838 49 49 0,000 0,07566502 0,0826619 ! response to nutrient GO:0007584 49 49 0,000 0,07566502 0,08261293 ! response to bacterium GO:0009617 50 49 0,000 0,07566502 0,08256402 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,07566502 0,08251517 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,07566502 0,08246637 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,07566502 0,08241763 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,07715348 0,08398929 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,07715348 0,08393971 ! negative regulation of transport GO:0051051 51 50 0,000 0,07715348 0,08389019 ! chromatin assembly GO:0031497 50 50 0,000 0,07715348 0,08384072 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 0,000 0,07715348 0,08379132 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,07715348 0,08374197 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,07715348 0,08369268 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,07715348 0,08364345 ! transcription initiation GO:0006352 50 50 0,000 0,07715348 0,08359428 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,07715348 0,08354516 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,07863976 0,08510457 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,07863976 0,08505463 ! positive regulation of immune response GO:0050778 51 51 0,000 0,07863976 0,08500474 ! rRNA metabolic process GO:0016072 51 51 0,000 0,07863976 0,08495492 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,07863976 0,08490515 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,07863976 0,08485544 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,07863976 0,08480579 ! protein maturation GO:0051604 51 51 0,000 0,07863976 0,08475619 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,08012387 0,08630526 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,08012387 0,08625485 ! cell fate commitment GO:0045165 52 52 0,000 0,08012387 0,08620449 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,08012387 0,0861542 ! response to light stimulus GO:0009416 53 52 0,000 0,08012387 0,08610396 ! sodium ion transport GO:0006814 53 53 0,000 0,0816058 0,08764539 ! tRNA metabolic process GO:0006399 53 53 0,000 0,0816058 0,08759435 ! response to hypoxia GO:0001666 53 53 0,000 0,0816058 0,08754336 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,0816058 0,08749244 ! regulation of T cell activation GO:0050863 53 53 0,000 0,0816058 0,08744157 ! regulation of protein transport GO:0051223 53 53 0,000 0,0816058 0,08739076 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,08308557 0,08892375 ! response to oxygen levels GO:0070482 55 54 0,000 0,08308557 0,08887214 ! response to virus GO:0009615 54 54 0,000 0,08308557 0,08882059 ! hormone metabolic process GO:0042445 55 54 0,000 0,08308557 0,0887691 ! sulfur metabolic process GO:0006790 55 54 0,000 0,08308557 0,08871767 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,08308557 0,0886663 ! nucleosome organization GO:0034728 55 55 0,000 0,08456316 0,09019092 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,08456316 0,09013875 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,08456316 0,09008665 ! in utero embryonic development GO:0001701 55 55 0,000 0,08456316 0,09003461 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,08456316 0,08998262 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,08603859 0,09149978 ! reproductive developmental process GO:0003006 56 56 0,000 0,08603859 0,09144701 ! extracellular structure organization GO:0043062 56 56 0,000 0,08603859 0,09139431 ! regulation of nervous system development GO:0051960 57 56 0,000 0,08603859 0,09134166 ! regulation of binding GO:0051098 60 57 0,000 0,08751186 0,09285225 ! ATP metabolic process GO:0046034 57 57 0,000 0,08751186 0,09279882 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,08751186 0,09274546 ! regulation of protein localization GO:0032880 58 57 0,000 0,08751186 0,09269216 ! innate immune response GO:0045087 58 58 0,000 0,08898297 0,09419621 ! dephosphorylation GO:0016311 60 59 0,000 0,09045192 0,09569626 ! carboxylic acid transport GO:0046942 59 59 0,000 0,09045192 0,09564136 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,09045192 0,09558652 ! regulation of cell development GO:0060284 60 59 0,000 0,09045192 0,09553174 ! sterol metabolic process GO:0016125 59 59 0,000 0,09045192 0,09547702 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,09045192 0,09542237 ! protein localization in organelle GO:0033365 59 59 0,000 0,09045192 0,09536778 ! immune effector process GO:0002252 59 59 0,000 0,09045192 0,09531325 ! potassium ion transport GO:0006813 60 60 0,000 0,09191871 0,09680354 ! protein polymerization GO:0051258 65 60 0,000 0,09191871 0,09674825 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,09338336 0,09823375 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,09338336 0,09817772 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,09484586 0,09965845 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,09484586 0,09960167 ! protein import GO:0017038 62 62 0,000 0,09484586 0,09954494 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,09484586 0,09948829 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,09484586 0,0994317 ! regulation of secretion GO:0051046 65 63 0,000 0,09630622 0,10090526 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,09630622 0,10084793 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,09630622 0,10079066 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,09630622 0,10073346 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,09776443 0,1022007 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,09776443 0,10214277 ! angiogenesis GO:0001525 65 64 0,000 0,09776443 0,1020849 ! anion transport GO:0006820 65 65 0,000 0,0992205 0,10354665 ! regulation of hormone levels GO:0010817 66 65 0,000 0,0992205 0,10348805 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,10067444 0,10494513 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,10067444 0,1048858 ! DNA packaging GO:0006323 66 66 0,000 0,10067444 0,10482655 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,10067444 0,10476736 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,10067444 0,10470823 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,10212624 0,1061583 ! response to radiation GO:0009314 70 68 0,000 0,10357591 0,10760451 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,10357591 0,10754389 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,10357591 0,10748333 ! sensory perception of sound GO:0007605 71 69 0,000 0,10502345 0,10892416 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,10502345 0,10886289 ! response to nutrient levels GO:0031667 69 69 0,000 0,10502345 0,1088017 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,10502345 0,10874058 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,10502345 0,10867952 ! positive regulation of transport GO:0051050 71 70 0,000 0,10646887 0,11011343 ! wound healing GO:0042060 74 70 0,000 0,10646887 0,11005167 ! growth GO:0040007 70 70 0,000 0,10646887 0,10998998 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,10646887 0,10992836 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,10791217 0,11135617 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,10791217 0,11129386 ! regulation of cell migration GO:0030334 71 71 0,000 0,10791217 0,11123161 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,10791217 0,11116944 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 0,000 0,10791217 0,11110733 ! secretion by cell GO:0032940 75 72 0,000 0,10935334 0,11252831 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,10935334 0,11246552 ! regulation of cytokine production GO:0001817 72 72 0,000 0,10935334 0,11240279 ! electron transport chain GO:0022900 75 74 0,000 0,11222935 0,1152947 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,11222935 0,11523047 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,11366418 0,11663869 ! response to oxidative stress GO:0006979 76 75 0,000 0,11366418 0,11657378 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,11366418 0,11650895 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,11509691 0,11791195 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,11652752 0,11931124 ! microtubule-based movement GO:0007018 82 78 0,000 0,11795604 0,12070682 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,11795604 0,12063984 ! metal ion homeostasis GO:0055065 78 78 0,000 0,11795604 0,12057292 ! regulation of immune response GO:0050776 78 78 0,000 0,11795604 0,12050609 ! regulation of locomotion GO:0040012 79 79 0,000 0,11938246 0,12189577 ! regulation of cell motion GO:0051270 79 79 0,000 0,11938246 0,12182828 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,12080678 0,12321355 ! MAPKKK cascade GO:0000165 82 81 0,000 0,122229 0,12459516 ! lymphocyte activation GO:0046649 82 81 0,000 0,122229 0,12452628 ! lipid catabolic process GO:0016042 82 81 0,000 0,122229 0,12445748 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,12506718 0,12727709 ! ncRNA processing GO:0034470 83 83 0,000 0,12506718 0,12720685 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,12506718 0,12713668 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,12648313 0,12850519 ! regulation of cellular localization GO:0060341 86 85 0,000 0,12789701 0,12987007 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,12789701 0,12979856 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,12789701 0,12972712 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,12789701 0,12965577 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,1293088 0,13101491 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,1293088 0,13094292 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,1293088 0,13087102 GO:0006644|phospholipid metabolic process, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,13212615 0,13364901 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,13212615 0,1335757 ! chemotaxis GO:0006935 90 89 0,000 0,13353172 0,13492268 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,13353172 0,13484875 ! brain development GO:0007420 91 90 0,000 0,13493522 0,13619146 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,13633665 0,13753062 ! DNA replication GO:0006260 91 91 0,000 0,13633665 0,13745539 ! visual perception GO:0007601 93 92 0,000 0,13773602 0,13879031 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,13773602 0,13871447 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,13773602 0,13863871 ! regulation of response to stress GO:0080134 97 94 0,000 0,14052857 0,14137235 ! blood vessel development GO:0001568 95 94 0,000 0,14052857 0,14129523 ! pattern specification process GO:0007389 96 94 0,000 0,14052857 0,14121818 ! cofactor metabolic process GO:0051186 95 94 0,000 0,14052857 0,14114123 ! vasculature development GO:0001944 97 96 0,000 0,14331289 0,14385929 ! endocytosis GO:0006897 99 98 0,000 0,14608902 0,14656617 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,14608902 0,14648643 ! blood circulation GO:0008015 99 98 0,000 0,14608902 0,14640677 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,14608902 0,14632721 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,14885696 0,14901867 ! response to other organism GO:0051707 101 100 0,000 0,14885696 0,14893777 ! hemopoiesis GO:0030097 104 100 0,000 0,14885696 0,14885696