pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/92359-11-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! alcohol catabolic process GO:0046164 142 87 5,000 4,678E-10 1,143E-06 ! establishment of cell polarity GO:0030010 21 12 3,000 5,461E-10 6,671E-07 ! polyol catabolic process GO:0046174 9 5 2,000 1,126E-08 9,166E-06 GO:0019405|alditol catabolic process, ! substrate-bound cell migration, cell extension GO:0006930 6 5 2,000 1,126E-08 6,875E-06 ! neural plate morphogenesis GO:0001839 7 5 2,000 1,126E-08 5,5E-06 ! actin filament organization GO:0007015 167 72 4,000 1,411E-08 5,744E-06 ! neural plate development GO:0001840 9 6 2,000 2,25E-08 7,851E-06 ! establishment or maintenance of cell polarity GO:0007163 96 41 3,000 1,093E-07 3,337E-05 ! glycolysis GO:0006096 71 46 3,000 1,754E-07 4,762E-05 ! substrate-bound cell migration GO:0006929 14 11 2,000 1,849E-07 4,517E-05 ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 3,2E-07 7,107E-05 ! glucose catabolic process GO:0006007 88 56 3,000 3,918E-07 7,977E-05 ! fructose metabolic process GO:0006000 25 16 2,000 6,252E-07 1,175E-04 ! hexose catabolic process GO:0019320 113 68 3,000 8,608E-07 1,502E-04 ! neural crest cell migration GO:0001755 41 18 2,000 9,097E-07 1,482E-04 ! cell-cell junction organization GO:0045216 43 20 2,000 1,269E-06 1,938E-04 ! regulation of actin cytoskeleton organization GO:0032956 167 76 3,000 1,348E-06 1,937E-04 ! monosaccharide catabolic process GO:0046365 125 77 3,000 1,421E-06 1,928E-04 ! regulation of actin filament-based process GO:0032970 170 79 3,000 1,575E-06 2,025E-04 ! positive regulation of cytoskeleton organization GO:0051495 52 24 2,000 2,246E-06 2,744E-04 ! neural crest cell development GO:0014032 59 26 2,000 2,882E-06 3,352E-04 GO:0014033|neural crest cell differentiation, ! alditol metabolic process GO:0019400 44 26 2,000 2,882E-06 3,2E-04 ! sperm motility GO:0030317 37 28 2,000 3,625E-06 3,851E-04 ! primary neural tube formation GO:0014020 61 29 2,000 4,041E-06 4,113E-04 ! regulation of actin filament depolymerization GO:0030834 67 30 2,000 4,486E-06 4,384E-04 ! hexose biosynthetic process GO:0019319 53 32 2,000 5,473E-06 5,142E-04 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 7,855E-06 7,107E-04 ! cell junction organization GO:0034330 96 37 2,000 8,542E-06 7,453E-04 ! neural tube formation GO:0001841 79 38 2,000 9,267E-06 7,807E-04 ! Rho protein signal transduction GO:0007266 88 40 2,000 1,084E-05 8,825E-04 ! negative regulation of protein ubiquitination GO:0031397 10 5 1,000 1,111E-05 8,753E-04 ! skeletal myofibril assembly GO:0014866 12 5 1,000 1,111E-05 8,479E-04 ! mesenchymal cell development GO:0014031 94 41 2,000 1,168E-05 8,65E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! embryonic epithelial tube formation GO:0001838 85 41 2,000 1,168E-05 8,395E-04 ! alcohol biosynthetic process GO:0046165 65 42 2,000 1,257E-05 8,776E-04 ! cytokinesis GO:0000910 84 42 2,000 1,257E-05 8,533E-04 ! polyol metabolic process GO:0019751 77 45 2,000 1,551E-05 1,024E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 1,665E-05 1,07E-03 GO:0046530|photoreceptor cell differentiation, ! activation of Ras GTPase activity GO:0032856 13 6 1,000 1,665E-05 1,043E-03 GO:0032862|activation of Rho GTPase activity, ! neural tube development GO:0021915 91 47 2,000 1,769E-05 1,081E-03 ! regulation of protein complex disassembly GO:0043244 127 52 2,000 2,403E-05 1,432E-03 ! morphogenesis of embryonic epithelium GO:0016331 106 52 2,000 2,403E-05 1,398E-03 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 2,693E-05 1,53E-03 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 2,000 2,846E-05 1,58E-03 ! regulation of focal adhesion formation GO:0051893 23 8 1,000 3,104E-05 1,685E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 1,000 3,104E-05 1,648E-03 ! regulation of actin filament length GO:0030832 118 58 2,000 3,34E-05 1,736E-03 ! positive regulation of organelle organization GO:0010638 108 58 2,000 3,34E-05 1,7E-03 ! regulation of cellular component size GO:0032535 125 61 2,000 3,887E-05 1,938E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 3,988E-05 1,948E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 4,981E-05 2,386E-03 ! regulation of stress fiber formation GO:0051492 34 10 1,000 4,981E-05 2,34E-03 ! cell projection assembly GO:0030031 138 68 2,000 5,385E-05 2,482E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 5,625E-05 2,545E-03 ! negative regulation of kinase activity GO:0033673 145 70 2,000 5,873E-05 2,609E-03 ! Golgi vesicle budding GO:0048194 26 11 1,000 6,084E-05 2,654E-03 ! keratinocyte proliferation GO:0043616 19 11 1,000 6,084E-05 2,608E-03 ! positive regulation of Rho GTPase activity GO:0032321 31 11 1,000 6,084E-05 2,563E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 6,084E-05 2,519E-03 ! regulation of actin filament bundle formation GO:0032231 37 11 1,000 6,084E-05 2,477E-03 ! negative regulation of transferase activity GO:0051348 155 74 2,000 6,934E-05 2,777E-03 ! axon guidance GO:0007411 162 75 2,000 7,218E-05 2,844E-03 ! positive regulation of cell growth GO:0030307 24 13 1,000 8,617E-05 3,341E-03 ! negative regulation of caspase activity GO:0043154 23 14 1,000 1,005E-04 3,835E-03 ! positive regulation of Ras GTPase activity GO:0032320 42 14 1,000 1,005E-04 3,776E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 1,005E-04 3,718E-03 ! positive regulation of GTPase activity GO:0043547 43 15 1,000 1,158E-04 4,224E-03 ! tube morphogenesis GO:0035239 194 89 2,000 1,201E-04 4,316E-03 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 1,323E-04 4,684E-03 ! positive regulation of cell size GO:0045793 29 16 1,000 1,323E-04 4,617E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 1,323E-04 4,552E-03 ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 1,413E-04 4,794E-03 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 1,498E-04 5,014E-03 ! membrane budding GO:0006900 42 17 1,000 1,498E-04 4,946E-03 ! skin development GO:0043588 42 20 1,000 2,089E-04 6,805E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 2,089E-04 6,715E-03 ! negative regulation of translation GO:0017148 32 20 1,000 2,089E-04 6,628E-03 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 2,776E-04 8,695E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of Rho GTPase activity GO:0032319 56 23 1,000 2,776E-04 8,585E-03 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 3,026E-04 9,242E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 3,287E-04 9,915E-03 ! negative regulation of protein modification process GO:0031400 66 28 1,000 4,134E-04 0,0123153 ! myofibril assembly GO:0030239 50 30 1,000 4,751E-04 0,01398275 GO:0055002|striated muscle cell development, ! eye morphogenesis GO:0048592 65 31 1,000 5,075E-04 0,01475918 ! muscle cell development GO:0055001 52 32 1,000 5,409E-04 0,01554743 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 6,11E-04 0,017357 ! protein targeting to membrane GO:0006612 75 36 1,000 6,852E-04 0,01924181 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 6,852E-04 0,01902315 ! actomyosin structure organization GO:0031032 68 37 1,000 7,239E-04 0,01987084 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 7,636E-04 0,02072774 ! RNA export from nucleus GO:0006405 61 41 1,000 8,889E-04 0,02386347 ! striated muscle cell differentiation GO:0051146 91 43 1,000 9,776E-04 0,02595828 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 1,07E-03 0,02811532 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 1,07E-03 0,02781622 ! keratinocyte differentiation GO:0030216 81 45 1,000 1,07E-03 0,02752342 ! response to insulin stimulus GO:0032868 98 47 1,000 1,167E-03 0,02970025 ! epidermal cell differentiation GO:0009913 87 50 1,000 1,32E-03 0,03324242 ! positive regulation of growth GO:0045927 96 53 1,000 1,482E-03 0,03693806 ! vesicle organization GO:0016050 127 53 1,000 1,482E-03 0,03656494 ! skeletal muscle fiber development GO:0048741 130 56 1,000 1,653E-03 0,04037332 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 1,712E-03 0,04139929 ! muscle fiber development GO:0048747 131 57 1,000 1,712E-03 0,04099342 ! nuclear export GO:0051168 110 59 1,000 1,832E-03 0,04346198 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 2,021E-03 0,04747644 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 2,152E-03 0,05006529 ! viral reproduction GO:0016032 142 68 1,000 2,425E-03 0,0558875 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 2,425E-03 0,05536519 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 2,496E-03 0,05645195 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 2,714E-03 0,06081809 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 2,714E-03 0,0602652 ! regulation of caspase activity GO:0043281 136 74 1,000 2,864E-03 0,06302545 ! eye development GO:0001654 155 75 1,000 2,94E-03 0,0641309 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 3,096E-03 0,06693208 ! positive regulation of ligase activity GO:0051351 130 77 1,000 3,096E-03 0,06634495 ! blood coagulation GO:0007596 151 79 1,000 3,256E-03 0,06915895 GO:0050817|coagulation, ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 3,256E-03 0,06856275 ! muscle cell differentiation GO:0042692 178 81 1,000 3,419E-03 0,07138877 ! regulation of peptidase activity GO:0052547 150 82 1,000 3,502E-03 0,07250463 ! regulation of ligase activity GO:0051340 147 84 1,000 3,671E-03 0,07536602 ! hemostasis GO:0007599 165 85 1,000 3,757E-03 0,07648747 ! mitochondrion organization GO:0007005 159 87 1,000 3,932E-03 0,07938201 ! cellular respiration GO:0045333 143 88 1,000 4,02E-03 0,0805082 ! response to unfolded protein GO:0006986 139 90 1,000 4,201E-03 0,08343379 ! regulation of cell adhesion GO:0030155 241 92 1,000 4,385E-03 0,08638507 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 4,478E-03 0,08751858 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 158 96 1,000 4,764E-03 0,09236106 ! skeletal muscle tissue development GO:0007519 223 100 1,000 5,157E-03 0,09920416 GO:0060538|skeletal muscle organ development, ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 5,334E-03 0,10181144 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 5,334E-03 0,1010222 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 5,334E-03 0,10024511 ! positive regulation of helicase activity GO:0051096 12 5 0,000 5,334E-03 0,09947988 ! neuron fate determination GO:0048664 7 5 0,000 5,334E-03 0,09872624 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,334E-03 0,09798394 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 5,334E-03 0,09725272 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 5,334E-03 0,09653233 ! polyol transport GO:0015791 12 5 0,000 5,334E-03 0,09582253 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 5,334E-03 0,0951231 ! response to superoxide GO:0000303 10 5 0,000 5,334E-03 0,0944338 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,334E-03 0,09375442 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 5,334E-03 0,09308474 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 5,334E-03 0,09242457 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 5,334E-03 0,09177369 ! female meiosis GO:0007143 10 5 0,000 5,334E-03 0,09113192 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 5,334E-03 0,09049906 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 5,334E-03 0,08987493 ! hypothalamus development GO:0021854 9 5 0,000 5,334E-03 0,08925934 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 5,334E-03 0,08865214 ! cobalt ion transport GO:0006824 11 5 0,000 5,334E-03 0,08805314 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 5,334E-03 0,08746218 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 5,334E-03 0,0868791 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 5,334E-03 0,08630374 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 5,334E-03 0,08573595 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 5,334E-03 0,08517558 ! embryonic camera-type eye development GO:0031076 12 5 0,000 5,334E-03 0,0846225 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 5,334E-03 0,08407654 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,334E-03 0,08353759 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 5,334E-03 0,0830055 ! transposition GO:0032196 9 5 0,000 5,334E-03 0,08248015 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 5,334E-03 0,08196141 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 5,334E-03 0,08144915 ! negative chemotaxis GO:0050919 16 5 0,000 5,334E-03 0,08094326 ! positive regulation of histone modification GO:0031058 6 5 0,000 5,334E-03 0,08044361 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,334E-03 0,07995009 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 5,334E-03 0,07946259 ! behavioral response to pain GO:0048266 10 5 0,000 5,334E-03 0,078981 ! clathrin coat assembly GO:0048268 15 5 0,000 5,334E-03 0,07850521 ! Notch receptor processing GO:0007220 11 5 0,000 5,334E-03 0,07803512 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,334E-03 0,07757062 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 5,334E-03 0,07711162 ! micturition GO:0060073 9 5 0,000 5,334E-03 0,07665803 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 5,334E-03 0,07620973 ! copulation GO:0007620 9 5 0,000 5,334E-03 0,07576665 ! glial cell fate commitment GO:0021781 14 5 0,000 5,334E-03 0,0753287 ! protein maturation by protein folding GO:0022417 14 5 0,000 5,334E-03 0,07489577 ! bioluminescence GO:0008218 9 5 0,000 5,334E-03 0,0744678 ! spermidine metabolic process GO:0008216 7 5 0,000 5,334E-03 0,07404468 ! regulation of potassium ion transport GO:0043266 10 5 0,000 5,334E-03 0,07362635 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 5,334E-03 0,07321272 ! apoptotic cell clearance GO:0043277 23 5 0,000 5,334E-03 0,07280371 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 5,334E-03 0,07239925 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 5,334E-03 0,07199925 ! lipoprotein particle clearance GO:0034381 10 5 0,000 5,334E-03 0,07160365 ! grooming behavior GO:0007625 6 5 0,000 5,334E-03 0,07121237 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 5,334E-03 0,07082535 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 5,334E-03 0,07044251 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 5,334E-03 0,07006379 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,334E-03 0,06968911 ! response to protozoan GO:0001562 13 5 0,000 5,334E-03 0,06931843 ! positive regulation of glycolysis GO:0045821 13 5 0,000 5,334E-03 0,06895166 ! lymph vessel development GO:0001945 10 5 0,000 5,334E-03 0,06858876 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 5,334E-03 0,06822966 ! endochondral ossification GO:0001958 17 5 0,000 5,334E-03 0,06787429 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 5,334E-03 0,06752261 ! single strand break repair GO:0000012 8 5 0,000 5,334E-03 0,06717456 ! parathyroid gland development GO:0060017 14 5 0,000 5,334E-03 0,06683007 ! anagen GO:0042640 7 5 0,000 5,334E-03 0,0664891 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 5,334E-03 0,0661516 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 5,334E-03 0,0658175 ! cytokine secretion GO:0050663 15 5 0,000 5,334E-03 0,06548676 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 5,334E-03 0,06515932 ! ceramide catabolic process GO:0046514 7 5 0,000 5,334E-03 0,06483515 ! smooth muscle tissue development GO:0048745 32 5 0,000 5,334E-03 0,06451418 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,334E-03 0,06419638 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 5,334E-03 0,06388169 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 5,334E-03 0,06357007 ! cardiac muscle fiber development GO:0048739 12 5 0,000 5,334E-03 0,06326148 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,334E-03 0,06295587 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 5,334E-03 0,06265319 ! neutrophil mediated immunity GO:0002446 7 5 0,000 5,334E-03 0,06235342 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 5,334E-03 0,0620565 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 5,334E-03 0,06176239 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 5,334E-03 0,06147106 ! glycine biosynthetic process GO:0006545 7 5 0,000 5,334E-03 0,06118246 ! microvillus organization GO:0032528 8 5 0,000 5,334E-03 0,06089656 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 5,334E-03 0,06061332 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 5,334E-03 0,0603327 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 5,334E-03 0,06005467 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 5,334E-03 0,05977919 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 5,334E-03 0,05950623 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 5,334E-03 0,05923575 ! polyol biosynthetic process GO:0046173 6 5 0,000 5,334E-03 0,05896771 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 5,334E-03 0,05870209 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,334E-03 0,05843885 ! muscle cell migration GO:0014812 8 5 0,000 5,334E-03 0,05817797 ! mitochondrial fission GO:0000266 8 5 0,000 5,334E-03 0,0579194 ! sister chromatid cohesion GO:0007062 15 5 0,000 5,334E-03 0,05766312 ! response to tumor necrosis factor GO:0034612 10 5 0,000 5,334E-03 0,05740909 ! mRNA transcription GO:0009299 10 5 0,000 5,334E-03 0,0571573 ! nerve growth factor processing GO:0032455 9 5 0,000 5,334E-03 0,0569077 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 5,334E-03 0,05666028 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 5,334E-03 0,056415 ! anaerobic glycolysis GO:0019642 6 5 0,000 5,334E-03 0,05617183 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 5,334E-03 0,05593075 ! monocyte activation GO:0042117 10 5 0,000 5,334E-03 0,05569173 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 5,334E-03 0,05545474 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 5,334E-03 0,05521976 ! response to food GO:0032094 6 5 0,000 5,334E-03 0,05498677 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 5,334E-03 0,05475573 ! positive regulation of transporter activity GO:0032411 8 5 0,000 5,334E-03 0,05452663 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 5,334E-03 0,05429943 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,334E-03 0,05407413 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 5,334E-03 0,05385068 ! forebrain neuron development GO:0021884 13 5 0,000 5,334E-03 0,05362907 ! lipoprotein catabolic process GO:0042159 11 5 0,000 5,334E-03 0,05340928 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 5,334E-03 0,05319128 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 5,334E-03 0,05297506 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,334E-03 0,05276058 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 5,334E-03 0,05254784 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 5,334E-03 0,0523368 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 5,334E-03 0,05212746 ! lipid glycosylation GO:0030259 7 5 0,000 5,334E-03 0,05191978 ! nucleobase transport GO:0015851 6 5 0,000 5,334E-03 0,05171375 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,334E-03 0,05150934 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 5,334E-03 0,05130655 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 5,334E-03 0,05110535 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 5,334E-03 0,05090572 ! basic amino acid transport GO:0015802 12 5 0,000 5,334E-03 0,05070764 ! cellular glucose homeostasis GO:0001678 6 5 0,000 5,334E-03 0,0505111 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 5,334E-03 0,05031608 ! actin nucleation GO:0045010 11 5 0,000 5,334E-03 0,05012255 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,334E-03 0,04993051 ! depurination GO:0045007 5 5 0,000 5,334E-03 0,04973994 ! depyrimidination GO:0045008 10 5 0,000 5,334E-03 0,04955081 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,334E-03 0,04936312 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,334E-03 0,04917685 ! G2/M transition checkpoint GO:0031576 8 5 0,000 5,334E-03 0,04899197 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 5,334E-03 0,04880848 ! zinc ion homeostasis GO:0055069 9 5 0,000 5,334E-03 0,04862636 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 5,334E-03 0,04844559 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 5,334E-03 0,04826616 ! forebrain morphogenesis GO:0048853 13 5 0,000 5,334E-03 0,04808806 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 5,334E-03 0,04791127 ! activated T cell proliferation GO:0050798 16 5 0,000 5,334E-03 0,04773577 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 5,334E-03 0,04756155 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 5,334E-03 0,0473886 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,334E-03 0,0472169 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,334E-03 0,04704644 ! gamma-delta T cell activation GO:0046629 6 5 0,000 5,334E-03 0,04687721 ! response to arsenic GO:0046685 11 5 0,000 5,334E-03 0,04670919 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 5,334E-03 0,04654237 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 5,334E-03 0,04637674 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 5,334E-03 0,04621228 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 5,334E-03 0,04604899 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 5,334E-03 0,04588685 ! response to mercury ion GO:0046689 8 5 0,000 5,334E-03 0,04572584 ! response to cadmium ion GO:0046686 7 5 0,000 5,334E-03 0,04556596 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 5,334E-03 0,04540719 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 5,334E-03 0,04524953 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 5,334E-03 0,04509296 ! bile acid biosynthetic process GO:0006699 7 5 0,000 5,334E-03 0,04493746 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,334E-03 0,04478304 ! ganglioside catabolic process GO:0006689 12 5 0,000 5,334E-03 0,04462967 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 5,334E-03 0,04447735 ! decidualization GO:0046697 11 5 0,000 5,334E-03 0,04432607 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 5,334E-03 0,04417581 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 5,334E-03 0,04402657 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 5,334E-03 0,04387833 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 5,334E-03 0,04373109 ! embryonic cleavage GO:0040016 6 5 0,000 5,334E-03 0,04358483 ! peroxisome fission GO:0016559 5 5 0,000 5,334E-03 0,04343955 ! histone demethylation GO:0016577 13 5 0,000 5,334E-03 0,04329523 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 5,334E-03 0,04315187 ! mitotic recombination GO:0006312 9 5 0,000 5,334E-03 0,04300945 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 5,334E-03 0,04286797 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,334E-03 0,04272742 ! metaphase plate congression GO:0051310 7 5 0,000 5,334E-03 0,04258779 ! regulation of sterol transport GO:0032371 7 5 0,000 5,334E-03 0,04244907 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 5,334E-03 0,04231125 ! enteric nervous system development GO:0048484 8 5 0,000 5,334E-03 0,04217432 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 5,334E-03 0,04203827 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 5,334E-03 0,0419031 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 5,334E-03 0,0417688 ! muscle cell proliferation GO:0033002 12 5 0,000 5,334E-03 0,04163535 ! skeletal muscle regeneration GO:0043403 8 5 0,000 5,334E-03 0,04150275 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 5,334E-03 0,041371 ! B cell homeostasis GO:0001782 13 5 0,000 5,334E-03 0,04124008 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 5,334E-03 0,04110998 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 5,334E-03 0,04098071 ! metaphase GO:0051323 11 5 0,000 5,334E-03 0,04085224 ! melatonin biosynthetic process GO:0030187 7 5 0,000 5,334E-03 0,04072458 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 5,334E-03 0,04059771 ! cellular response to nutrient GO:0031670 8 5 0,000 5,334E-03 0,04047163 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 5,334E-03 0,04034633 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 5,334E-03 0,0402218 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 5,334E-03 0,04009804 ! regulation of hair follicle development GO:0051797 10 5 0,000 5,334E-03 0,03997504 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 5,334E-03 0,0398528 ! response to redox state GO:0051775 6 5 0,000 5,334E-03 0,03973129 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 5,334E-03 0,03961053 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 5,334E-03 0,0394905 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,334E-03 0,03937119 ! brown fat cell differentiation GO:0050873 7 5 0,000 5,334E-03 0,0392526 ! regulation of telomerase activity GO:0051972 7 5 0,000 5,334E-03 0,03913473 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,334E-03 0,03901756 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 5,334E-03 0,03890109 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,334E-03 0,03878531 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 5,334E-03 0,03867022 ! striatum development GO:0021756 14 5 0,000 5,334E-03 0,03855581 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 5,334E-03 0,03844208 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 5,334E-03 0,03832901 ! glial cell migration GO:0008347 10 5 0,000 5,334E-03 0,03821661 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,334E-03 0,03810487 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 5,334E-03 0,03799377 ! somatic stem cell maintenance GO:0035019 15 5 0,000 5,334E-03 0,03788333 ! T cell activation during immune response GO:0002286 9 5 0,000 5,334E-03 0,03777352 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 5,334E-03 0,03766435 ! negative regulation of lipase activity GO:0060192 8 5 0,000 5,334E-03 0,0375558 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 5,334E-03 0,03744789 ! neuroprotection GO:0043526 8 5 0,000 5,334E-03 0,03734059 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 5,334E-03 0,0372339 ! regulation of sensory perception GO:0051931 8 5 0,000 5,334E-03 0,03712782 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 5,334E-03 0,03702234 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 5,334E-03 0,03691746 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 5,334E-03 0,03681318 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 5,334E-03 0,03670948 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 5,334E-03 0,03660636 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 5,334E-03 0,03650382 ! sequestering of calcium ion GO:0051208 7 5 0,000 5,334E-03 0,03640186 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 5,334E-03 0,03630046 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 5,334E-03 0,03619962 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 5,334E-03 0,03609935 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 5,334E-03 0,03599963 ! spindle assembly GO:0051225 6 5 0,000 5,334E-03 0,03590045 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 5,334E-03 0,03580182 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 5,334E-03 0,03570374 ! protein palmitoylation GO:0018345 12 5 0,000 5,334E-03 0,03560619 ! drug metabolic process GO:0017144 7 5 0,000 5,334E-03 0,03550917 ! stem cell division GO:0017145 11 5 0,000 5,334E-03 0,03541267 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 5,334E-03 0,03531671 ! organ regeneration GO:0031100 7 5 0,000 5,334E-03 0,03522125 ! carnitine metabolic process GO:0009437 8 5 0,000 5,334E-03 0,03512632 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 5,334E-03 0,03503189 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 6,398E-03 0,04190376 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,398E-03 0,04179172 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 6,398E-03 0,04168027 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 6,398E-03 0,04156942 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 6,398E-03 0,04145916 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 6,398E-03 0,04134948 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 6,398E-03 0,04124038 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 6,398E-03 0,04113185 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 6,398E-03 0,04102389 ! response to oxygen radical GO:0000305 11 6 0,000 6,398E-03 0,0409165 ! positive regulation of axon extension GO:0045773 13 6 0,000 6,398E-03 0,04080967 ! myoblast cell fate commitment GO:0048625 18 6 0,000 6,398E-03 0,04070339 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 6,398E-03 0,04059767 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 6,398E-03 0,04049249 ! regulation of interferon-beta production GO:0032648 8 6 0,000 6,398E-03 0,04038786 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 6,398E-03 0,04028377 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 6,398E-03 0,04018021 ! forebrain regionalization GO:0021871 9 6 0,000 6,398E-03 0,04007719 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 6,398E-03 0,03997469 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 6,398E-03 0,03987271 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 6,398E-03 0,03977125 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 6,398E-03 0,03967031 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 6,398E-03 0,03956988 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 6,398E-03 0,03946996 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 6,398E-03 0,03937054 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 6,398E-03 0,03927161 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 6,398E-03 0,03917319 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 6,398E-03 0,03907526 ! malate metabolic process GO:0006108 13 6 0,000 6,398E-03 0,03897781 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 6,398E-03 0,03888085 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 6,398E-03 0,03878437 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 6,398E-03 0,03868837 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 6,398E-03 0,03859285 ! protein refolding GO:0042026 15 6 0,000 6,398E-03 0,03849779 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 6,398E-03 0,0384032 ! opsonization GO:0008228 8 6 0,000 6,398E-03 0,03830907 ! mating behavior GO:0007617 7 6 0,000 6,398E-03 0,03821541 ! erythrocyte maturation GO:0043249 8 6 0,000 6,398E-03 0,0381222 ! embryonic hemopoiesis GO:0035162 16 6 0,000 6,398E-03 0,03802945 ! protein amino acid dealkylation GO:0008214 15 6 0,000 6,398E-03 0,03793714 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 6,398E-03 0,03784528 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 6,398E-03 0,03775387 ! response to interferon-gamma GO:0034341 16 6 0,000 6,398E-03 0,0376629 ! toxin metabolic process GO:0009404 11 6 0,000 6,398E-03 0,03757236 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 6,398E-03 0,03748226 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 6,398E-03 0,03739259 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 6,398E-03 0,03730335 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 6,398E-03 0,03721453 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 6,398E-03 0,03712613 ! cGMP-mediated signaling GO:0019934 14 6 0,000 6,398E-03 0,03703816 ! dorsal spinal cord development GO:0021516 10 6 0,000 6,398E-03 0,0369506 ! activation of MAPKKK activity GO:0000185 12 6 0,000 6,398E-03 0,03686345 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 6,398E-03 0,03677671 ! thymic T cell selection GO:0045061 16 6 0,000 6,398E-03 0,03669038 ! sphingoid catabolic process GO:0046521 8 6 0,000 6,398E-03 0,03660446 ! protein lipoylation GO:0009249 10 6 0,000 6,398E-03 0,03651893 ! transepithelial chloride transport GO:0030321 12 6 0,000 6,398E-03 0,03643381 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 6,398E-03 0,03634908 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 6,398E-03 0,03626474 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 6,398E-03 0,03618079 ! glutamate catabolic process GO:0006538 12 6 0,000 6,398E-03 0,03609723 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 6,398E-03 0,03601406 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 6,398E-03 0,03593127 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 6,398E-03 0,03584886 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 6,398E-03 0,03576682 ! hyperosmotic response GO:0006972 10 6 0,000 6,398E-03 0,03568517 ! L-serine biosynthetic process GO:0006564 7 6 0,000 6,398E-03 0,03560388 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 6,398E-03 0,03552296 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 6,398E-03 0,03544241 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 6,398E-03 0,03536222 ! urea metabolic process GO:0019627 7 6 0,000 6,398E-03 0,0352824 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 6,398E-03 0,03520293 ! neutrophil activation GO:0042119 7 6 0,000 6,398E-03 0,03512383 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 6,398E-03 0,03504507 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 6,398E-03 0,03496667 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 6,398E-03 0,03488862 ! paraxial mesoderm development GO:0048339 16 6 0,000 6,398E-03 0,03481092 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 6,398E-03 0,03473356 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 6,398E-03 0,03465655 ! neuron apoptosis GO:0051402 15 6 0,000 6,398E-03 0,03457987 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 6,398E-03 0,03450354 ! T cell mediated immunity GO:0002456 17 6 0,000 6,398E-03 0,03442754 ! negative regulation of platelet activation GO:0010544 9 6 0,000 6,398E-03 0,03435187 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 6,398E-03 0,03427654 ! carnitine transport GO:0015879 10 6 0,000 6,398E-03 0,03420154 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,398E-03 0,03412686 ! positive regulation of exocytosis GO:0045921 11 6 0,000 6,398E-03 0,03405251 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 6,398E-03 0,03397848 ! early endosome to late endosome transport GO:0045022 16 6 0,000 6,398E-03 0,03390478 ! 5S class rRNA transcription GO:0042791 13 6 0,000 6,398E-03 0,03383139 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 6,398E-03 0,03375832 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 6,398E-03 0,03368557 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 6,398E-03 0,03361312 ! sodium ion homeostasis GO:0055078 12 6 0,000 6,398E-03 0,03354099 ! establishment of spindle localization GO:0051293 16 6 0,000 6,398E-03 0,03346917 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 6,398E-03 0,03339765 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 6,398E-03 0,03332644 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 6,398E-03 0,03325554 ! response to UV-C GO:0010225 14 6 0,000 6,398E-03 0,03318493 ! astrocyte development GO:0014002 16 6 0,000 6,398E-03 0,03311462 ! protein targeting to lysosome GO:0006622 12 6 0,000 6,398E-03 0,03304461 ! purine base biosynthetic process GO:0009113 17 6 0,000 6,398E-03 0,0329749 ! interaction with symbiont GO:0051702 14 6 0,000 6,398E-03 0,03290548 ! regulation of dendrite development GO:0050773 16 6 0,000 6,398E-03 0,03283635 ! peptidyl-arginine modification GO:0018195 13 6 0,000 6,398E-03 0,03276751 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 6,398E-03 0,03269896 ! response to copper ion GO:0046688 10 6 0,000 6,398E-03 0,03263069 ! response to exogenous dsRNA GO:0043330 13 6 0,000 6,398E-03 0,03256271 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 6,398E-03 0,03249502 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,398E-03 0,0324276 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 6,398E-03 0,03236046 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 6,398E-03 0,0322936 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 6,398E-03 0,03222702 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,398E-03 0,0321607 ! nucleoside catabolic process GO:0009164 10 6 0,000 6,398E-03 0,03209467 ! hair follicle maturation GO:0048820 8 6 0,000 6,398E-03 0,0320289 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 6,398E-03 0,0319634 ! Schwann cell development GO:0014044 15 6 0,000 6,398E-03 0,03189817 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 6,398E-03 0,0318332 ! response to pheromone GO:0019236 6 6 0,000 6,398E-03 0,0317685 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 6,398E-03 0,03170406 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 6,398E-03 0,03163988 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 6,398E-03 0,03157596 ! base conversion or substitution editing GO:0016553 6 6 0,000 6,398E-03 0,0315123 ! subpallium development GO:0021544 15 6 0,000 6,398E-03 0,0314489 ! neural tube patterning GO:0021532 8 6 0,000 6,398E-03 0,03138575 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 6,398E-03 0,03132285 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 6,398E-03 0,03126021 ! maintenance of organ identity GO:0048496 9 6 0,000 6,398E-03 0,03119781 ! G2 phase GO:0051319 16 6 0,000 6,398E-03 0,03113566 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 6,398E-03 0,03107376 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 6,398E-03 0,03101211 ! oxygen homeostasis GO:0032364 10 6 0,000 6,398E-03 0,0309507 ! establishment of planar polarity GO:0001736 7 6 0,000 6,398E-03 0,03088953 ! regulation of mast cell activation GO:0033003 13 6 0,000 6,398E-03 0,0308286 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 6,398E-03 0,03076792 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 6,398E-03 0,03070747 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 6,398E-03 0,03064726 ! receptor internalization GO:0031623 11 6 0,000 6,398E-03 0,03058728 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 6,398E-03 0,03052754 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 6,398E-03 0,03046804 ! neutrophil homeostasis GO:0001780 11 6 0,000 6,398E-03 0,03040876 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,398E-03 0,03034971 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 6,398E-03 0,0302909 ! protein deubiquitination GO:0016579 16 6 0,000 6,398E-03 0,03023231 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 6,398E-03 0,03017394 ! protein destabilization GO:0031648 9 6 0,000 6,398E-03 0,0301158 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 6,398E-03 0,03005789 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 6,398E-03 0,0300002 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 6,398E-03 0,02994273 ! regulation of viral transcription GO:0046782 11 6 0,000 6,398E-03 0,02988547 ! progesterone metabolic process GO:0042448 12 6 0,000 6,398E-03 0,02982844 ! negative regulation of axon extension GO:0030517 24 6 0,000 6,398E-03 0,02977162 ! removal of superoxide radicals GO:0019430 12 6 0,000 6,398E-03 0,02971502 ! triglyceride catabolic process GO:0019433 10 6 0,000 6,398E-03 0,02965864 ! determination of adult lifespan GO:0008340 17 6 0,000 6,398E-03 0,02960247 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 6,398E-03 0,02954651 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 6,398E-03 0,02949076 ! catecholamine transport GO:0051937 9 6 0,000 6,398E-03 0,02943522 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 6,398E-03 0,02937989 ! sensory cilium assembly GO:0035058 10 6 0,000 6,398E-03 0,02932477 ! organ or tissue specific immune response GO:0002251 8 6 0,000 6,398E-03 0,02926985 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 6,398E-03 0,02921514 ! maternal placenta development GO:0001893 12 6 0,000 6,398E-03 0,02916064 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 6,398E-03 0,02910634 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 6,398E-03 0,02905224 ! negative regulation of B cell activation GO:0050869 14 6 0,000 6,398E-03 0,02899833 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 6,398E-03 0,02894463 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 6,398E-03 0,02889113 ! positive regulation of coagulation GO:0050820 13 6 0,000 6,398E-03 0,02883783 ! cellular anion homeostasis GO:0030002 11 6 0,000 6,398E-03 0,02878472 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 7,46E-03 0,03350301 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 7,46E-03 0,03344153 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 7,46E-03 0,03338029 ! behavioral response to cocaine GO:0048148 14 7 0,000 7,46E-03 0,03331926 ! regulation of helicase activity GO:0051095 16 7 0,000 7,46E-03 0,03325846 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 7,46E-03 0,03319788 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 7,46E-03 0,03313752 ! sleep GO:0030431 16 7 0,000 7,46E-03 0,03307738 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 7,46E-03 0,03301746 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 7,46E-03 0,03295775 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 7,46E-03 0,03289826 ! prostate gland development GO:0030850 14 7 0,000 7,46E-03 0,03283898 ! nucleotide-sugar transport GO:0015780 11 7 0,000 7,46E-03 0,03277992 ! synaptonemal complex assembly GO:0007130 10 7 0,000 7,46E-03 0,03272107 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 7,46E-03 0,03266243 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 7,46E-03 0,032604 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,46E-03 0,03254578 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 7,46E-03 0,03248776 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 7,46E-03 0,03242996 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 7,46E-03 0,03237235 ! SMAD protein complex assembly GO:0007183 13 7 0,000 7,46E-03 0,03231496 ! glycolipid transport GO:0046836 11 7 0,000 7,46E-03 0,03225776 ! protein amino acid sulfation GO:0006477 10 7 0,000 7,46E-03 0,03220077 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 7,46E-03 0,03214398 ! neuron adhesion GO:0007158 14 7 0,000 7,46E-03 0,03208739 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 7,46E-03 0,03203099 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 7,46E-03 0,0319748 ! establishment of tissue polarity GO:0007164 8 7 0,000 7,46E-03 0,0319188 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 7,46E-03 0,031863 ! mRNA stabilization GO:0048255 18 7 0,000 7,46E-03 0,03180739 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 7,46E-03 0,03175198 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 7,46E-03 0,03169676 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 7,46E-03 0,03164173 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 7,46E-03 0,03158689 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 7,46E-03 0,03153224 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 7,46E-03 0,03147778 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 7,46E-03 0,03142351 ! lipoprotein transport GO:0042953 14 7 0,000 7,46E-03 0,03136942 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 7,46E-03 0,03131553 ! rhythmic behavior GO:0007622 17 7 0,000 7,46E-03 0,03126181 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 7,46E-03 0,03120828 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 7,46E-03 0,03115493 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 7,46E-03 0,03110177 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 7,46E-03 0,03104878 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 7,46E-03 0,03099598 ! regulation of odontogenesis GO:0042481 14 7 0,000 7,46E-03 0,03094335 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 7,46E-03 0,03089091 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 7,46E-03 0,03083864 ! mechanosensory behavior GO:0007638 16 7 0,000 7,46E-03 0,03078655 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 7,46E-03 0,03073463 ! positive regulation of isotype switching GO:0045830 17 7 0,000 7,46E-03 0,03068289 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 7,46E-03 0,03063132 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 7,46E-03 0,03057993 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,46E-03 0,0305287 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,46E-03 0,03047765 ! spinal cord patterning GO:0021511 14 7 0,000 7,46E-03 0,03042677 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 7,46E-03 0,03037606 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 7,46E-03 0,03032552 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 7,46E-03 0,03027514 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 7,46E-03 0,03022493 ! adrenal gland development GO:0030325 17 7 0,000 7,46E-03 0,03017489 ! cysteine metabolic process GO:0006534 13 7 0,000 7,46E-03 0,03012502 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 7,46E-03 0,03007531 ! ovulation GO:0030728 10 7 0,000 7,46E-03 0,03002576 ! adenohypophysis development GO:0021984 11 7 0,000 7,46E-03 0,02997637 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 7,46E-03 0,02992715 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 7,46E-03 0,02987809 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 7,46E-03 0,02982919 ! microtubule nucleation GO:0007020 21 7 0,000 7,46E-03 0,02978045 ! proline biosynthetic process GO:0006561 10 7 0,000 7,46E-03 0,02973187 ! tryptophan metabolic process GO:0006568 11 7 0,000 7,46E-03 0,02968345 ! thyroid hormone generation GO:0006590 13 7 0,000 7,46E-03 0,02963518 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 7,46E-03 0,02958707 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 7,46E-03 0,02953912 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 7,46E-03 0,02949132 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 7,46E-03 0,02944368 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 7,46E-03 0,02939619 ! galactose metabolic process GO:0006012 13 7 0,000 7,46E-03 0,02934885 ! vesicle fusion GO:0006906 20 7 0,000 7,46E-03 0,02930167 ! response to dietary excess GO:0002021 8 7 0,000 7,46E-03 0,02925463 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 7,46E-03 0,02920775 ! intracellular pH reduction GO:0051452 13 7 0,000 7,46E-03 0,02916102 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 7,46E-03 0,02911443 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 7,46E-03 0,029068 ! organ growth GO:0035265 15 7 0,000 7,46E-03 0,02902171 ! nucleoside transport GO:0015858 11 7 0,000 7,46E-03 0,02897557 ! nucleoside salvage GO:0043174 11 7 0,000 7,46E-03 0,02892958 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 7,46E-03 0,02888373 ! male sex determination GO:0030238 15 7 0,000 7,46E-03 0,02883803 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 7,46E-03 0,02879247 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 7,46E-03 0,02874706 ! parturition GO:0007567 16 7 0,000 7,46E-03 0,02870179 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 7,46E-03 0,02865666 ! rRNA modification GO:0000154 14 7 0,000 7,46E-03 0,02861167 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 7,46E-03 0,02856683 ! spindle checkpoint GO:0031577 16 7 0,000 7,46E-03 0,02852212 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 7,46E-03 0,02847756 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 7,46E-03 0,02843313 ! monocyte differentiation GO:0030224 16 7 0,000 7,46E-03 0,02838884 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 7,46E-03 0,02834469 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 7,46E-03 0,02830068 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 7,46E-03 0,0282568 ! hyaluronan metabolic process GO:0030212 9 7 0,000 7,46E-03 0,02821306 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 7,46E-03 0,02816945 ! anterograde axon cargo transport GO:0008089 18 7 0,000 7,46E-03 0,02812598 ! fibrinolysis GO:0042730 11 7 0,000 7,46E-03 0,02808264 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 7,46E-03 0,02803944 ! skeletal muscle contraction GO:0003009 8 7 0,000 7,46E-03 0,02799637 ! eating behavior GO:0042755 8 7 0,000 7,46E-03 0,02795343 ! B cell lineage commitment GO:0002326 21 7 0,000 7,46E-03 0,02791062 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 7,46E-03 0,02786794 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 7,46E-03 0,0278254 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 7,46E-03 0,02778298 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 7,46E-03 0,02774069 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 7,46E-03 0,02769853 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 7,46E-03 0,0276565 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 7,46E-03 0,0276146 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 7,46E-03 0,02757282 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 7,46E-03 0,02753117 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 7,46E-03 0,02748965 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 7,46E-03 0,02744825 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 7,46E-03 0,02740697 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 7,46E-03 0,02736582 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 7,46E-03 0,02732479 ! histone ubiquitination GO:0016574 9 7 0,000 7,46E-03 0,02728389 ! regulation of meiosis GO:0040020 12 7 0,000 7,46E-03 0,0272431 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 7,46E-03 0,02720244 ! T cell lineage commitment GO:0002360 16 7 0,000 7,46E-03 0,0271619 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 7,46E-03 0,02712148 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 7,46E-03 0,02708118 ! membrane to membrane docking GO:0022614 14 7 0,000 7,46E-03 0,027041 ! transcription termination GO:0006353 14 7 0,000 7,46E-03 0,02700094 ! coenzyme A metabolic process GO:0015936 12 7 0,000 7,46E-03 0,026961 ! anaphase GO:0051322 18 7 0,000 7,46E-03 0,02692118 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 7,46E-03 0,02688147 ! axonal fasciculation GO:0007413 19 7 0,000 7,46E-03 0,02684188 ! negative regulation of nuclear division GO:0051784 15 7 0,000 7,46E-03 0,02680241 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 7,46E-03 0,02676305 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 7,46E-03 0,02672381 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 7,46E-03 0,02668468 ! diuresis GO:0030146 12 7 0,000 7,46E-03 0,02664567 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 7,46E-03 0,02660677 ! thiamin metabolic process GO:0006772 7 7 0,000 7,46E-03 0,02656798 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 7,46E-03 0,02652931 ! antibiotic transport GO:0042891 9 7 0,000 7,46E-03 0,02649075 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,46E-03 0,0264523 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 7,46E-03 0,02641396 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 7,46E-03 0,02637574 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 7,46E-03 0,02633762 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 7,46E-03 0,02629962 ! melanin biosynthetic process GO:0042438 10 7 0,000 7,46E-03 0,02626172 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 7,46E-03 0,02622394 ! dopamine biosynthetic process GO:0042416 18 7 0,000 7,46E-03 0,02618626 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 7,46E-03 0,02614869 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 7,46E-03 0,02611123 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 7,46E-03 0,02607387 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 7,46E-03 0,02603662 ! endosome to lysosome transport GO:0008333 12 7 0,000 7,46E-03 0,02599948 ! protein modification by small protein removal GO:0070646 19 7 0,000 7,46E-03 0,02596244 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 7,46E-03 0,02592551 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 7,46E-03 0,02588869 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 7,46E-03 0,02585197 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 7,46E-03 0,02581535 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 7,46E-03 0,02577883 ! muscle adaptation GO:0043500 13 7 0,000 7,46E-03 0,02574242 ! embryonic heart tube development GO:0035050 14 7 0,000 7,46E-03 0,02570612 ! retina homeostasis GO:0001895 12 7 0,000 7,46E-03 0,02566991 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 7,46E-03 0,02563381 ! protein amino acid prenylation GO:0018346 19 7 0,000 7,46E-03 0,0255978 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 7,46E-03 0,0255619 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 7,46E-03 0,0255261 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 8,522E-03 0,02911674 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 8,522E-03 0,02907607 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 8,522E-03 0,02903552 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 8,522E-03 0,02899508 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 8,522E-03 0,02895475 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 8,522E-03 0,02891454 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 8,522E-03 0,02887443 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 8,522E-03 0,02883444 ! male meiosis GO:0007140 9 8 0,000 8,522E-03 0,02879456 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 8,522E-03 0,02875479 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 8,522E-03 0,02871513 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 8,522E-03 0,02867557 ! meiotic prophase I GO:0007128 14 8 0,000 8,522E-03 0,02863613 ! response to zinc ion GO:0010043 12 8 0,000 8,522E-03 0,02859679 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 8,522E-03 0,02855757 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 8,522E-03 0,02851845 ! oligopeptide transport GO:0006857 16 8 0,000 8,522E-03 0,02847943 ! actin-myosin filament sliding GO:0033275 13 8 0,000 8,522E-03 0,02844053 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 8,522E-03 0,02840173 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 8,522E-03 0,02836303 ! signal peptide processing GO:0006465 12 8 0,000 8,522E-03 0,02832444 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 8,522E-03 0,02828596 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 8,522E-03 0,02824758 ! macrophage chemotaxis GO:0048246 12 8 0,000 8,522E-03 0,0282093 ! succinate metabolic process GO:0006105 17 8 0,000 8,522E-03 0,02817113 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 8,522E-03 0,02813306 ! membrane hyperpolarization GO:0060081 11 8 0,000 8,522E-03 0,0280951 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 8,522E-03 0,02805723 ! estrogen metabolic process GO:0008210 17 8 0,000 8,522E-03 0,02801947 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 8,522E-03 0,02798181 ! T-helper 1 type immune response GO:0042088 12 8 0,000 8,522E-03 0,02794425 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 8,522E-03 0,02790679 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 8,522E-03 0,02786943 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 8,522E-03 0,02783217 ! reflex GO:0060004 17 8 0,000 8,522E-03 0,02779502 ! endothelial cell differentiation GO:0045446 17 8 0,000 8,522E-03 0,02775796 ! glycerolipid catabolic process GO:0046503 14 8 0,000 8,522E-03 0,02772099 ! hemoglobin metabolic process GO:0020027 14 8 0,000 8,522E-03 0,02768413 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 8,522E-03 0,02764737 ! pigment granule organization GO:0048753 17 8 0,000 8,522E-03 0,0276107 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 8,522E-03 0,02757413 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 8,522E-03 0,02753765 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 8,522E-03 0,02750128 ! astrocyte differentiation GO:0048708 19 8 0,000 8,522E-03 0,027465 ! histidine catabolic process GO:0006548 10 8 0,000 8,522E-03 0,02742881 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 8,522E-03 0,02739272 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 8,522E-03 0,02735672 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 8,522E-03 0,02732082 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 8,522E-03 0,02728501 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 8,522E-03 0,0272493 ! regulation of pigmentation during development GO:0048070 25 8 0,000 8,522E-03 0,02721368 ! melanin metabolic process GO:0006582 17 8 0,000 8,522E-03 0,02717815 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 8,522E-03 0,02714272 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 8,522E-03 0,02710738 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 8,522E-03 0,02707213 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 8,522E-03 0,02703697 ! macrophage activation GO:0042116 13 8 0,000 8,522E-03 0,0270019 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 8,522E-03 0,02696693 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 8,522E-03 0,02693204 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 8,522E-03 0,02689724 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 8,522E-03 0,02686254 ! purine salvage GO:0043101 12 8 0,000 8,522E-03 0,02682792 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 8,522E-03 0,02679339 ! regulation of vascular permeability GO:0043114 12 8 0,000 8,522E-03 0,02675895 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 8,522E-03 0,0267246 ! osteoblast development GO:0002076 17 8 0,000 8,522E-03 0,02669034 ! positive regulation of vasodilation GO:0045909 14 8 0,000 8,522E-03 0,02665617 ! negative regulation of translational initiation GO:0045947 12 8 0,000 8,522E-03 0,02662208 ! Schwann cell differentiation GO:0014037 21 8 0,000 8,522E-03 0,02658808 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 8,522E-03 0,02655417 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 8,522E-03 0,02652034 ! response to UV-B GO:0010224 17 8 0,000 8,522E-03 0,0264866 ! protein targeting to vacuole GO:0006623 14 8 0,000 8,522E-03 0,02645294 ! protein retention in ER lumen GO:0006621 14 8 0,000 8,522E-03 0,02641937 ! intermediate filament organization GO:0045109 12 8 0,000 8,522E-03 0,02638589 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 8,522E-03 0,02635249 ! cellular extravasation GO:0045123 13 8 0,000 8,522E-03 0,02631917 ! cardiac muscle cell development GO:0055013 14 8 0,000 8,522E-03 0,02628594 ! response to antibiotic GO:0046677 11 8 0,000 8,522E-03 0,02625279 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 8,522E-03 0,02621973 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 8,522E-03 0,02618675 ! DNA topological change GO:0006265 12 8 0,000 8,522E-03 0,02615385 ! response to tropane GO:0014073 15 8 0,000 8,522E-03 0,02612104 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 8,522E-03 0,0260883 ! melanosome transport GO:0032402 13 8 0,000 8,522E-03 0,02605565 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 8,522E-03 0,02602308 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 8,522E-03 0,02599059 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 8,522E-03 0,02595819 ! mast cell activation GO:0045576 14 8 0,000 8,522E-03 0,02592586 ! multicellular organismal aging GO:0010259 20 8 0,000 8,522E-03 0,02589361 ! gas homeostasis GO:0033483 14 8 0,000 8,522E-03 0,02586145 ! dendrite morphogenesis GO:0048813 14 8 0,000 8,522E-03 0,02582936 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 8,522E-03 0,02579736 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 8,522E-03 0,02576543 ! nucleosome disassembly GO:0006337 14 8 0,000 8,522E-03 0,02573358 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 8,522E-03 0,02570181 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 8,522E-03 0,02567012 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 8,522E-03 0,02563851 ! establishment of chromosome localization GO:0051303 14 8 0,000 8,522E-03 0,02560697 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 8,522E-03 0,02557551 ! intracellular lipid transport GO:0032365 16 8 0,000 8,522E-03 0,02554413 ! response to tumor cell GO:0002347 16 8 0,000 8,522E-03 0,02551283 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 8,522E-03 0,0254816 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 8,522E-03 0,02545045 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 8,522E-03 0,02541937 ! positive regulation of epidermis development GO:0045684 13 8 0,000 8,522E-03 0,02538837 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 8,522E-03 0,02535745 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 8,522E-03 0,0253266 ! hormone catabolic process GO:0042447 17 8 0,000 8,522E-03 0,02529583 ! glycolipid catabolic process GO:0019377 16 8 0,000 8,522E-03 0,02526513 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 8,522E-03 0,0252345 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 8,522E-03 0,02520395 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 8,522E-03 0,02517348 ! positive regulation of glucose import GO:0046326 8 8 0,000 8,522E-03 0,02514308 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 8,522E-03 0,02511275 ! adult feeding behavior GO:0008343 10 8 0,000 8,522E-03 0,02508249 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 8,522E-03 0,02505231 ! ATP catabolic process GO:0006200 11 8 0,000 8,522E-03 0,0250222 ! blastocyst growth GO:0001832 19 8 0,000 8,522E-03 0,02499216 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 8,522E-03 0,02496219 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 8,522E-03 0,0249323 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 8,522E-03 0,02490247 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 8,522E-03 0,02487272 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 8,522E-03 0,02484304 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 8,522E-03 0,02481343 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 8,522E-03 0,02478389 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 8,522E-03 0,02475442 ! amino sugar catabolic process GO:0046348 11 8 0,000 8,522E-03 0,02472502 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 8,522E-03 0,02469569 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 8,522E-03 0,02466643 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 8,522E-03 0,02463724 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 8,522E-03 0,02460812 ! behavioral response to nicotine GO:0035095 12 8 0,000 8,522E-03 0,02457906 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 8,522E-03 0,02455008 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 8,522E-03 0,02452116 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 8,522E-03 0,02449231 ! NAD biosynthetic process GO:0009435 17 8 0,000 8,522E-03 0,02446353 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 8,522E-03 0,02443482 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 8,522E-03 0,02440617 ! axon extension GO:0048675 16 9 0,000 9,582E-03 0,02741054 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 9,582E-03 0,02737848 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 9,582E-03 0,02734649 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 9,582E-03 0,02731458 ! pentose-phosphate shunt GO:0006098 16 9 0,000 9,582E-03 0,02728275 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 9,582E-03 0,02725099 ! cell proliferation in forebrain GO:0021846 18 9 0,000 9,582E-03 0,0272193 ! neutral lipid catabolic process GO:0046461 14 9 0,000 9,582E-03 0,02718769 ! reproductive behavior GO:0019098 22 9 0,000 9,582E-03 0,02715615 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 9,582E-03 0,02712468 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 9,582E-03 0,02709328 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 9,582E-03 0,02706196 ! UTP metabolic process GO:0046051 10 9 0,000 9,582E-03 0,02703071 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 9,582E-03 0,02699954 ! induction of positive chemotaxis GO:0050930 17 9 0,000 9,582E-03 0,02696843 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 9,582E-03 0,0269374 ! artery development GO:0060840 25 9 0,000 9,582E-03 0,02690643 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 9,582E-03 0,02687554 ! regulation of glycolysis GO:0006110 20 9 0,000 9,582E-03 0,02684472 ! cerebral cortex cell migration GO:0021795 18 9 0,000 9,582E-03 0,02681397 ! equilibrioception GO:0050957 20 9 0,000 9,582E-03 0,02678329 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 9,582E-03 0,02675268 ! chemosensory behavior GO:0007635 21 9 0,000 9,582E-03 0,02672214 ! microtubule bundle formation GO:0001578 22 9 0,000 9,582E-03 0,02669167 ! middle ear morphogenesis GO:0042474 14 9 0,000 9,582E-03 0,02666127 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 9,582E-03 0,02663094 ! leukocyte degranulation GO:0043299 16 9 0,000 9,582E-03 0,02660068 ! ganglioside metabolic process GO:0001573 22 9 0,000 9,582E-03 0,02657049 ! negative regulation of endocytosis GO:0045806 12 9 0,000 9,582E-03 0,02654036 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 9,582E-03 0,0265103 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 9,582E-03 0,02648031 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 9,582E-03 0,02645039 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 9,582E-03 0,02642054 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 9,582E-03 0,02639075 ! protein targeting to ER GO:0045047 25 9 0,000 9,582E-03 0,02636103 ! ceramide biosynthetic process GO:0046513 20 9 0,000 9,582E-03 0,02633138 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 9,582E-03 0,02630179 ! T cell selection GO:0045058 27 9 0,000 9,582E-03 0,02627228 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 9,582E-03 0,02624282 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 9,582E-03 0,02621343 ! glycine catabolic process GO:0006546 15 9 0,000 9,582E-03 0,02618411 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 9,582E-03 0,02615486 ! endosome organization GO:0007032 20 9 0,000 9,582E-03 0,02612567 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 9,582E-03 0,02609654 ! regulation of type I interferon production GO:0032479 12 9 0,000 9,582E-03 0,02606748 ! mannose metabolic process GO:0006013 13 9 0,000 9,582E-03 0,02603848 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 9,582E-03 0,02600955 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 9,582E-03 0,02598069 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 9,582E-03 0,02595188 ! Rac protein signal transduction GO:0016601 20 9 0,000 9,582E-03 0,02592314 ! receptor clustering GO:0043113 20 9 0,000 9,582E-03 0,02589447 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 9,582E-03 0,02586585 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 9,582E-03 0,0258373 ! retinol metabolic process GO:0042572 20 9 0,000 9,582E-03 0,02580882 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 9,582E-03 0,02578039 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 9,582E-03 0,02575203 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 9,582E-03 0,02572373 ! macrophage differentiation GO:0030225 15 9 0,000 9,582E-03 0,0256955 ! oligodendrocyte development GO:0014003 11 9 0,000 9,582E-03 0,02566732 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 9,582E-03 0,02563921 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 9,582E-03 0,02561116 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 9,582E-03 0,02558317 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 9,582E-03 0,02555524 ! response to amine stimulus GO:0014075 13 9 0,000 9,582E-03 0,02552737 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 9,582E-03 0,02549956 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 9,582E-03 0,02547181 ! erythrocyte development GO:0048821 17 9 0,000 9,582E-03 0,02544413 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 9,582E-03 0,0254165 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 9,582E-03 0,02538893 ! renal water homeostasis GO:0003091 15 9 0,000 9,582E-03 0,02536143 ! postreplication repair GO:0006301 25 9 0,000 9,582E-03 0,02533398 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 9,582E-03 0,02530659 ! icosanoid secretion GO:0032309 15 9 0,000 9,582E-03 0,02527926 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 9,582E-03 0,02525199 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 9,582E-03 0,02522478 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 9,582E-03 0,02519763 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 9,582E-03 0,02517053 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 9,582E-03 0,0251435 ! sterol catabolic process GO:0016127 14 9 0,000 9,582E-03 0,02511652 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 9,582E-03 0,0250896 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 9,582E-03 0,02506274 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 9,582E-03 0,02503593 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 9,582E-03 0,02500919 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 9,582E-03 0,02498249 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 9,582E-03 0,02495586 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 9,582E-03 0,02492928 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 9,582E-03 0,02490276 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 9,582E-03 0,0248763 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 9,582E-03 0,02484989 ! regulation of synaptogenesis GO:0051963 15 9 0,000 9,582E-03 0,02482354 ! purine base metabolic process GO:0006144 25 9 0,000 9,582E-03 0,02479724 ! pigment granule transport GO:0051904 17 9 0,000 9,582E-03 0,024771 ! regulation of telomere maintenance GO:0032204 17 9 0,000 9,582E-03 0,02474482 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 9,582E-03 0,02471869 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 9,582E-03 0,02469261 ! regulation of muscle adaptation GO:0043502 14 9 0,000 9,582E-03 0,02466659 ! regulation of amino acid transport GO:0051955 12 9 0,000 9,582E-03 0,02464063 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 9,582E-03 0,02461472 ! mitochondrion localization GO:0051646 18 9 0,000 9,582E-03 0,02458886 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01064103 0,0272781 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01064103 0,02724951 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01064103 0,02722098 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01064103 0,0271925 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01064103 0,02716409 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01064103 0,02713573 ! associative learning GO:0008306 21 10 0,000 0,01064103 0,02710744 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01064103 0,0270792 ! phosphate transport GO:0006817 24 10 0,000 0,01064103 0,02705102 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01064103 0,0270229 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01064103 0,02699484 ! CTP metabolic process GO:0046036 11 10 0,000 0,01064103 0,02696684 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01064103 0,02693889 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01064103 0,02691101 ! GTP metabolic process GO:0046039 11 10 0,000 0,01064103 0,02688318 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01064103 0,0268554 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01064103 0,02682769 ! social behavior GO:0035176 29 10 0,000 0,01064103 0,02680003 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01064103 0,02677243 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01064103 0,02674489 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01064103 0,0267174 ! androgen metabolic process GO:0008209 17 10 0,000 0,01064103 0,02668997 ! phospholipid efflux GO:0033700 19 10 0,000 0,01064103 0,0266626 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01064103 0,02663528 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01064103 0,02660802 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01064103 0,02658081 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01064103 0,02655366 ! lung alveolus development GO:0048286 26 10 0,000 0,01064103 0,02652656 ! pathogenesis GO:0009405 17 10 0,000 0,01064103 0,02649952 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01064103 0,02647254 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01064103 0,02644561 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01064103 0,02641873 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01064103 0,02639191 ! endoderm development GO:0007492 18 10 0,000 0,01064103 0,02636514 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01064103 0,02633843 ! arginine catabolic process GO:0006527 17 10 0,000 0,01064103 0,02631177 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01064103 0,02628517 ! proline metabolic process GO:0006560 13 10 0,000 0,01064103 0,02625862 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01064103 0,02623212 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01064103 0,02620568 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01064103 0,02617929 ! V(D)J recombination GO:0033151 34 10 0,000 0,01064103 0,02615295 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01064103 0,02612666 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01064103 0,02610043 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 19 10 0,000 0,01064103 0,02607425 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01064103 0,02604813 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01064103 0,02602205 ! multicellular organism growth GO:0035264 19 10 0,000 0,01064103 0,02599603 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01064103 0,02597006 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01064103 0,02594414 ! ruffle organization GO:0031529 17 10 0,000 0,01064103 0,02591828 ! epithelial cell development GO:0002064 21 10 0,000 0,01064103 0,02589246 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01064103 0,0258667 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01064103 0,02584099 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01064103 0,02581532 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01064103 0,02578971 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01064103 0,02576415 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01064103 0,02573865 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01064103 0,02571319 ! motor axon guidance GO:0008045 22 10 0,000 0,01064103 0,02568778 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01064103 0,02566242 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01064103 0,02563711 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01064103 0,02561185 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01064103 0,02558665 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01064103 0,02556149 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01064103 0,02553638 ! segment specification GO:0007379 15 10 0,000 0,01064103 0,02551132 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01064103 0,02548631 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01064103 0,02546134 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01064103 0,02543643 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01064103 0,02541157 ! response to dsRNA GO:0043331 23 10 0,000 0,01064103 0,02538675 ! DNA ligation GO:0006266 18 10 0,000 0,01064103 0,02536198 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01064103 0,02533726 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01064103 0,02531259 ! melanosome localization GO:0032400 16 10 0,000 0,01064103 0,02528797 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01064103 0,02526339 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01064103 0,02523887 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01064103 0,02521439 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01064103 0,02518995 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01064103 0,02516557 ! induction of an organ GO:0001759 17 10 0,000 0,01064103 0,02514123 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01064103 0,02511694 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01064103 0,02509269 ! protein sumoylation GO:0016925 17 10 0,000 0,01064103 0,0250685 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01064103 0,02504435 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01064103 0,02502024 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01064103 0,02499618 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01064103 0,02497217 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01064103 0,02494821 ! salivary gland development GO:0007431 28 10 0,000 0,01064103 0,02492429 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01064103 0,02490041 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01064103 0,02487659 ! midbrain development GO:0030901 14 10 0,000 0,01064103 0,0248528 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01064103 0,02482907 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01064103 0,02480537 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01064103 0,02478173 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01064103 0,02475813 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01064103 0,02473457 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01064103 0,02471106 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01064103 0,02468759 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01064103 0,02466417 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01064103 0,02464079 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01064103 0,02461745 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01064103 0,02459416 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01064103 0,02457092 ! blastocyst formation GO:0001825 18 10 0,000 0,01064103 0,02454772 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01064103 0,02452456 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01064103 0,02450144 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01064103 0,02447837 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01064103 0,02445534 ! response to nicotine GO:0035094 20 10 0,000 0,01064103 0,02443236 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01064103 0,02440942 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01064103 0,02438652 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01169905 0,0267861 ! respiratory burst GO:0045730 17 11 0,000 0,01169905 0,02676102 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01169905 0,02673599 ! neuron fate specification GO:0048665 18 11 0,000 0,01169905 0,026711 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01169905 0,02668606 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01169905 0,02666117 ! thyroid gland development GO:0030878 26 11 0,000 0,01169905 0,02663632 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01169905 0,02661152 ! synapsis GO:0007129 14 11 0,000 0,01169905 0,02658676 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01169905 0,02656206 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01169905 0,02653739 ! response to pain GO:0048265 27 11 0,000 0,01169905 0,02651278 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01169905 0,0264882 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01169905 0,02646368 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01169905 0,0264392 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01169905 0,02641476 ! bone resorption GO:0045453 16 11 0,000 0,01169905 0,02639037 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01169905 0,02636603 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01169905 0,02634172 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01169905 0,02631747 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01169905 0,02629326 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01169905 0,02626909 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01169905 0,02624497 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01169905 0,02622089 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01169905 0,02619686 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01169905 0,02617287 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01169905 0,02614892 ! UV protection GO:0009650 20 11 0,000 0,01169905 0,02612502 ! adult heart development GO:0007512 16 11 0,000 0,01169905 0,02610116 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01169905 0,02607735 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01169905 0,02605357 ! macroautophagy GO:0016236 19 11 0,000 0,01169905 0,02602985 ! temperature homeostasis GO:0001659 18 11 0,000 0,01169905 0,02600616 ! behavioral fear response GO:0001662 27 11 0,000 0,01169905 0,02598252 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01169905 0,02595892 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01169905 0,02593536 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01169905 0,02591185 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01169905 0,02588838 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01169905 0,02586495 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01169905 0,02584157 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01169905 0,02581822 ! regulation of organ growth GO:0046620 14 11 0,000 0,01169905 0,02579492 ! pigment granule localization GO:0051875 20 11 0,000 0,01169905 0,02577166 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01169905 0,02574844 ! vasoconstriction GO:0042310 20 11 0,000 0,01169905 0,02572527 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01169905 0,02570213 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01169905 0,02567904 ! embryonic axis specification GO:0000578 19 11 0,000 0,01169905 0,02565599 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01169905 0,02563298 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01169905 0,02561001 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01169905 0,02558708 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01169905 0,0255642 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01169905 0,02554135 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01169905 0,02551855 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01169905 0,02549578 ! prophase GO:0051324 17 11 0,000 0,01169905 0,02547306 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01169905 0,02545038 ! nucleosome positioning GO:0016584 15 11 0,000 0,01169905 0,02542773 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01169905 0,02540513 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01169905 0,02538257 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01169905 0,02536005 ! apical protein localization GO:0045176 18 11 0,000 0,01169905 0,02533756 ! acid secretion GO:0046717 20 11 0,000 0,01169905 0,02531512 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01169905 0,02529272 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01169905 0,02527036 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01169905 0,02524803 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01169905 0,02522575 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01169905 0,0252035 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01169905 0,0251813 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01169905 0,02515913 ! cholesterol efflux GO:0033344 21 11 0,000 0,01169905 0,025137 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01169905 0,02511491 ! oocyte development GO:0048599 20 11 0,000 0,01169905 0,02509286 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01169905 0,02507085 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01169905 0,02504888 ! embryonic gut development GO:0048566 19 11 0,000 0,01169905 0,02502695 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01169905 0,02500505 ! activation of innate immune response GO:0002218 16 11 0,000 0,01169905 0,02498319 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01169905 0,02496137 ! lysogeny GO:0030069 22 11 0,000 0,01169905 0,02493959 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01169905 0,02491785 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01169905 0,02489614 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01169905 0,02487447 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01169905 0,02485284 ! nucleus localization GO:0051647 22 11 0,000 0,01169905 0,02483125 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01275596 0,02705106 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01275596 0,0270276 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01275596 0,02700418 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01275596 0,0269808 ! virus-host interaction GO:0019048 30 12 0,000 0,01275596 0,02695746 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,01275596 0,02693416 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01275596 0,0269109 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01275596 0,02688768 ! protein complex disassembly GO:0043241 28 12 0,000 0,01275596 0,0268645 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01275596 0,02684136 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01275596 0,02681826 ! hippocampus development GO:0021766 29 12 0,000 0,01275596 0,0267952 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01275596 0,02677218 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01275596 0,0267492 ! T cell proliferation GO:0042098 32 12 0,000 0,01275596 0,02672626 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01275596 0,02670336 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01275596 0,0266805 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01275596 0,02665767 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01275596 0,02663489 ! drug transport GO:0015893 16 12 0,000 0,01275596 0,02661214 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01275596 0,02658944 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01275596 0,02656677 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01275596 0,02654414 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01275596 0,02652155 ! focal adhesion formation GO:0048041 37 12 0,000 0,01275596 0,026499 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01275596 0,02647648 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01275596 0,02645401 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01275596 0,02643157 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01275596 0,02640917 ! lipid digestion GO:0044241 21 12 0,000 0,01275596 0,02638681 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01275596 0,02636448 ! entry into host cell GO:0030260 34 12 0,000 0,01275596 0,0263422 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01275596 0,02631995 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01275596 0,02629774 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01275596 0,02627557 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01275596 0,02625343 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01275596 0,02623133 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01275596 0,02620927 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01275596 0,02618724 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01275596 0,02616526 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01275596 0,02614331 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01275596 0,02612139 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01275596 0,02609951 ! cranial nerve development GO:0021545 23 12 0,000 0,01275596 0,02607767 ! fucose catabolic process GO:0019317 25 12 0,000 0,01275596 0,02605587 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01275596 0,0260341 ! histone acetylation GO:0016573 27 12 0,000 0,01275596 0,02601237 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01275596 0,02599068 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01275596 0,02596902 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01275596 0,02594739 ! zymogen activation GO:0031638 18 12 0,000 0,01275596 0,02592581 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01275596 0,02590426 ! T cell homeostasis GO:0043029 28 12 0,000 0,01275596 0,02588274 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01275596 0,02586126 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01275596 0,02583982 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01275596 0,02581841 ! oocyte differentiation GO:0009994 21 12 0,000 0,01275596 0,02579704 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01275596 0,0257757 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01275596 0,0257544 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01275596 0,02573313 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01275596 0,0257119 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01275596 0,0256907 ! defense response to fungus GO:0050832 15 12 0,000 0,01275596 0,02566954 ! developmental induction GO:0031128 22 12 0,000 0,01275596 0,02564841 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01275596 0,02562732 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01275596 0,02560626 ! response to cold GO:0009409 17 12 0,000 0,01275596 0,02558524 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01275596 0,02556425 ! localization within membrane GO:0051668 26 12 0,000 0,01275596 0,0255433 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01381178 0,02763487 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01381178 0,02761226 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01381178 0,02758968 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01381178 0,02756714 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01381178 0,02754464 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01381178 0,02752217 ! peroxisomal transport GO:0043574 28 13 0,000 0,01381178 0,02749974 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01381178 0,02747735 ! cartilage condensation GO:0001502 22 13 0,000 0,01381178 0,02745499 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01381178 0,02743267 ! organelle fusion GO:0048284 36 13 0,000 0,01381178 0,02741038 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01381178 0,02738813 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01381178 0,02736592 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01381178 0,02734374 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01381178 0,0273216 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01381178 0,0272995 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01381178 0,02727743 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01381178 0,0272554 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01381178 0,0272334 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01381178 0,02721144 ! methionine metabolic process GO:0006555 31 13 0,000 0,01381178 0,02718951 ! plasma membrane organization GO:0007009 27 13 0,000 0,01381178 0,02716762 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01381178 0,02714576 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01381178 0,02712394 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01381178 0,02710215 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01381178 0,0270804 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01381178 0,02705868 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01381178 0,027037 ! exocrine system development GO:0035272 34 13 0,000 0,01381178 0,02701536 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01381178 0,02699374 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01381178 0,02697217 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01381178 0,02695062 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01381178 0,02692911 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01381178 0,02690764 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01381178 0,0268862 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01381178 0,02686479 ! protein homotetramerization GO:0051289 24 13 0,000 0,01381178 0,02684342 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01381178 0,02682208 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01381178 0,02680078 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01381178 0,02677951 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01381178 0,02675827 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01381178 0,02673707 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01381178 0,0267159 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01381178 0,02669476 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01381178 0,02667366 ! histone methylation GO:0016571 29 13 0,000 0,01381178 0,02665259 ! chromatin silencing GO:0006342 29 13 0,000 0,01381178 0,02663155 ! gland morphogenesis GO:0022612 31 13 0,000 0,01381178 0,02661055 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01381178 0,02658958 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01381178 0,02656865 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01381178 0,02654774 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01381178 0,02652687 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01381178 0,02650603 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01381178 0,02648523 ! spleen development GO:0048536 24 13 0,000 0,01381178 0,02646445 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01381178 0,02644371 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01381178 0,02642301 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01381178 0,02640233 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01381178 0,02638169 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01381178 0,02636108 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01381178 0,0263405 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01381178 0,02631995 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01381178 0,02629944 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01381178 0,02627896 ! insulin secretion GO:0030073 24 13 0,000 0,01381178 0,02625851 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01381178 0,02623809 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01381178 0,0262177 ! acrosome reaction GO:0007340 19 13 0,000 0,01381178 0,02619734 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01381178 0,02617702 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01381178 0,02615673 ! rRNA transcription GO:0009303 28 14 0,000 0,0148665 0,02813234 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,0148665 0,02811057 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,0148665 0,02808883 ! water transport GO:0006833 21 14 0,000 0,0148665 0,02806712 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,0148665 0,02804545 ! non-recombinational repair GO:0000726 29 14 0,000 0,0148665 0,02802381 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,0148665 0,0280022 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,0148665 0,02798063 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,0148665 0,02795909 ! RNA polyadenylation GO:0043631 32 14 0,000 0,0148665 0,02793758 ! lipid localization GO:0010876 32 14 0,000 0,0148665 0,02791611 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,0148665 0,02789466 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,0148665 0,02787326 ! regulated secretory pathway GO:0045055 24 14 0,000 0,0148665 0,02785188 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,0148665 0,02783054 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,0148665 0,02780923 ! arginine metabolic process GO:0006525 21 14 0,000 0,0148665 0,02778795 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,0148665 0,02776671 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,0148665 0,0277455 ! regulation of heart rate GO:0002027 25 14 0,000 0,0148665 0,02772432 ! fear response GO:0042596 34 14 0,000 0,0148665 0,02770317 ! organic alcohol transport GO:0015850 29 14 0,000 0,0148665 0,02768205 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,0148665 0,02766097 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0148665 0,02763992 ! neutral amino acid transport GO:0015804 28 14 0,000 0,0148665 0,0276189 ! bone mineralization GO:0030282 18 14 0,000 0,0148665 0,02759791 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,0148665 0,02757696 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,0148665 0,02755603 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,0148665 0,02753514 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,0148665 0,02751428 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,0148665 0,02749345 ! regulation of cellular pH GO:0030641 27 14 0,000 0,0148665 0,02747266 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,0148665 0,02745189 ! ribosome assembly GO:0042255 18 14 0,000 0,0148665 0,02743116 ! cerebellum development GO:0021549 23 14 0,000 0,0148665 0,02741046 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,0148665 0,02738978 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,0148665 0,02736914 ! response to gamma radiation GO:0010332 30 14 0,000 0,0148665 0,02734853 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,0148665 0,02732796 ! NADP metabolic process GO:0006739 24 14 0,000 0,0148665 0,02730741 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,0148665 0,02728689 ! oxygen transport GO:0015671 22 14 0,000 0,0148665 0,02726641 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0148665 0,02724595 ! male genitalia development GO:0030539 26 14 0,000 0,0148665 0,02722553 ! regulation of RNA stability GO:0043487 33 14 0,000 0,0148665 0,02720513 ! regulation of axon extension GO:0030516 43 14 0,000 0,0148665 0,02718477 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,0148665 0,02716444 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,0148665 0,02714414 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01592012 0,02904619 ! lactation GO:0007595 30 15 0,000 0,01592012 0,02902451 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01592012 0,02900287 ! reproductive cellular process GO:0048610 22 15 0,000 0,01592012 0,02898126 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01592012 0,02895968 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01592012 0,02893813 ! superoxide anion generation GO:0042554 22 15 0,000 0,01592012 0,02891661 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01592012 0,02889513 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01592012 0,02887368 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01592012 0,02885226 ! copper ion transport GO:0006825 22 15 0,000 0,01592012 0,02883087 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01592012 0,02880951 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01592012 0,02878819 ! sulfate transport GO:0008272 27 15 0,000 0,01592012 0,0287669 ! response to cAMP GO:0051591 25 15 0,000 0,01592012 0,02874564 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01592012 0,0287244 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01592012 0,02870321 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01592012 0,02868204 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01592012 0,0286609 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01592012 0,0286398 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01592012 0,02861872 ! vesicle coating GO:0006901 38 15 0,000 0,01592012 0,02859768 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01592012 0,02857667 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01592012 0,02855569 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01592012 0,02853474 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01592012 0,02851382 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01592012 0,02849293 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01592012 0,02847207 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01592012 0,02845124 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01592012 0,02843044 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01592012 0,02840967 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01592012 0,02838894 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01592012 0,02836823 ! histone deacetylation GO:0016575 24 15 0,000 0,01592012 0,02834755 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01592012 0,02832691 ! water homeostasis GO:0030104 28 15 0,000 0,01592012 0,02830629 ! cofactor transport GO:0051181 30 15 0,000 0,01592012 0,0282857 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01592012 0,02826515 ! muscle maintenance GO:0046716 26 15 0,000 0,01592012 0,02824462 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01592012 0,02822413 ! intestinal absorption GO:0050892 31 15 0,000 0,01592012 0,02820366 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01592012 0,02818322 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01592012 0,02816281 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01592012 0,02814243 ! cell killing GO:0001906 32 15 0,000 0,01592012 0,02812209 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01592012 0,02810177 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01592012 0,02808148 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01592012 0,02806122 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01592012 0,02804098 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01592012 0,02802078 ! actin filament polymerization GO:0030041 27 15 0,000 0,01592012 0,02800061 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01592012 0,02798046 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01697264 0,02980888 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01697264 0,02978747 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01697264 0,02976608 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01697264 0,02974473 ! bone remodeling GO:0046849 28 16 0,000 0,01697264 0,02972341 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01697264 0,02970212 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01697264 0,02968085 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01697264 0,02965962 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01697264 0,02963842 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01697264 0,02961725 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01697264 0,02959611 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01697264 0,029575 ! startle response GO:0001964 28 16 0,000 0,01697264 0,02955392 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01697264 0,02953287 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01697264 0,02951185 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01697264 0,02949086 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01697264 0,0294699 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01697264 0,02944897 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01697264 0,02942807 ! pituitary gland development GO:0021983 30 16 0,000 0,01697264 0,0294072 ! response to osmotic stress GO:0006970 27 16 0,000 0,01697264 0,02938636 ! lysosomal transport GO:0007041 31 16 0,000 0,01697264 0,02936555 ! L-amino acid transport GO:0015807 33 16 0,000 0,01697264 0,02934477 ! stem cell development GO:0048864 46 16 0,000 0,01697264 0,02932401 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01697264 0,02930329 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 0,01697264 0,02928259 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01697264 0,02926193 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01697264 0,02924129 ! axon cargo transport GO:0008088 46 16 0,000 0,01697264 0,02922069 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01697264 0,02920011 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01697264 0,02917956 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01697264 0,02915904 ! DNA replication initiation GO:0006270 28 16 0,000 0,01697264 0,02913855 ! neuron recognition GO:0008038 40 16 0,000 0,01697264 0,02911809 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01697264 0,02909765 ! tissue regeneration GO:0042246 27 16 0,000 0,01697264 0,02907725 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01697264 0,02905687 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01697264 0,02903652 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01697264 0,0290162 ! biomineral formation GO:0031214 22 16 0,000 0,01697264 0,02899591 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01697264 0,02897565 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01697264 0,02895541 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01697264 0,02893521 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01697264 0,02891503 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01697264 0,02889488 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01697264 0,02887476 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01697264 0,02885467 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01697264 0,0288346 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01697264 0,02881456 ! peptide hormone processing GO:0016486 27 16 0,000 0,01697264 0,02879455 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,01802406 0,0305571 ! metencephalon development GO:0022037 32 17 0,000 0,01802406 0,03053591 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,01802406 0,03051475 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,01802406 0,03049362 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,01802406 0,03047252 ! signal complex assembly GO:0007172 47 17 0,000 0,01802406 0,03045144 ! filopodium assembly GO:0046847 42 17 0,000 0,01802406 0,0304304 ! endothelial cell migration GO:0043542 31 17 0,000 0,01802406 0,03040938 ! gene silencing by RNA GO:0031047 38 17 0,000 0,01802406 0,0303884 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,01802406 0,03036744 ! glial cell development GO:0021782 28 17 0,000 0,01802406 0,03034651 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,01802406 0,03032561 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,01802406 0,03030474 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,01802406 0,0302839 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,01802406 0,03026308 ! myoblast differentiation GO:0045445 50 17 0,000 0,01802406 0,0302423 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,01802406 0,03022154 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,01802406 0,03020081 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,01802406 0,03018011 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,01802406 0,03015944 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,01802406 0,0301388 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,01802406 0,03011818 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,01802406 0,0300976 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,01802406 0,03007704 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,01802406 0,03005651 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,01802406 0,03003601 ! regulation of protein binding GO:0043393 33 17 0,000 0,01802406 0,03001553 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,01802406 0,02999509 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,01802406 0,02997467 ! genitalia development GO:0048806 32 17 0,000 0,01802406 0,02995428 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,01802406 0,02993391 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,01802406 0,02991358 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,01802406 0,02989327 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,01802406 0,02987299 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,01802406 0,02985274 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,01802406 0,02983251 ! steroid catabolic process GO:0006706 34 17 0,000 0,01802406 0,02981231 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,01802406 0,02979214 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,01802406 0,029772 ! gas transport GO:0015669 26 17 0,000 0,01802406 0,02975188 ! organic cation transport GO:0015695 32 17 0,000 0,01802406 0,02973179 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,01802406 0,02971173 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,01802406 0,0296917 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,01802406 0,02967169 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,01907439 0,03137963 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,01907439 0,03135851 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,01907439 0,03133742 ! limbic system development GO:0021761 40 18 0,000 0,01907439 0,03131636 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01907439 0,03129533 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,01907439 0,03127432 ! adult walking behavior GO:0007628 36 18 0,000 0,01907439 0,03125335 ! patterning of blood vessels GO:0001569 43 18 0,000 0,01907439 0,0312324 ! heart looping GO:0001947 34 18 0,000 0,01907439 0,03121148 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,01907439 0,03119059 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,01907439 0,03116973 ! centrosome cycle GO:0007098 26 18 0,000 0,01907439 0,03114889 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,01907439 0,03112809 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,01907439 0,03110731 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,01907439 0,03108655 ! glycine metabolic process GO:0006544 30 18 0,000 0,01907439 0,03106583 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01907439 0,03104513 ! response to retinoic acid GO:0032526 31 18 0,000 0,01907439 0,03102446 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,01907439 0,03100382 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,01907439 0,03098321 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,01907439 0,03096262 ! DNA integration GO:0015074 32 18 0,000 0,01907439 0,03094206 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,01907439 0,03092153 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,01907439 0,03090102 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,01907439 0,03088055 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,01907439 0,03086009 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,01907439 0,03083967 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,01907439 0,03081927 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,01907439 0,03079891 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,01907439 0,03077856 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,01907439 0,03075825 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,01907439 0,03073796 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,01907439 0,0307177 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,01907439 0,03069746 ! detection of bacterium GO:0016045 22 18 0,000 0,01907439 0,03067725 ! nerve development GO:0021675 34 18 0,000 0,01907439 0,03065707 ! defense response to virus GO:0051607 43 18 0,000 0,01907439 0,03063691 ! microspike assembly GO:0030035 46 18 0,000 0,01907439 0,03061678 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,01907439 0,03059668 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,01907439 0,0305766 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02012363 0,0322374 ! positive regulation of translation GO:0045727 31 19 0,000 0,02012363 0,03221627 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02012363 0,03219517 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02012363 0,0321741 ! neuron maturation GO:0042551 46 19 0,000 0,02012363 0,03215306 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02012363 0,03213204 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02012363 0,03211106 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02012363 0,0320901 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02012363 0,03206916 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02012363 0,03204826 ! inositol metabolic process GO:0006020 33 19 0,000 0,02012363 0,03202738 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02012363 0,03200653 ! memory GO:0007613 34 19 0,000 0,02012363 0,0319857 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02012363 0,03196491 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02012363 0,03194414 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02012363 0,03192339 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02012363 0,03190268 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02012363 0,03188199 ! cerebral cortex development GO:0021987 40 19 0,000 0,02012363 0,03186133 ! pigmentation during development GO:0048066 42 19 0,000 0,02012363 0,03184069 ! response to vitamin A GO:0033189 32 19 0,000 0,02012363 0,03182008 ! heme metabolic process GO:0042168 40 19 0,000 0,02012363 0,0317995 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02012363 0,03177895 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02012363 0,03175842 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02012363 0,03173791 ! response to fungus GO:0009620 26 19 0,000 0,02012363 0,03171744 ! peptide cross-linking GO:0018149 39 19 0,000 0,02012363 0,03169699 ! protein export from nucleus GO:0006611 40 19 0,000 0,02012363 0,03167656 ! heart process GO:0003015 32 19 0,000 0,02012363 0,03165617 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02012363 0,0316358 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02012363 0,03161545 ! visual learning GO:0008542 38 19 0,000 0,02012363 0,03159513 ! cellular pigmentation GO:0033059 37 19 0,000 0,02012363 0,03157484 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02012363 0,03155458 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02012363 0,03153433 ! vitamin transport GO:0051180 31 19 0,000 0,02012363 0,03151412 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02012363 0,03149393 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02012363 0,03147377 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02012363 0,03145363 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02012363 0,03143352 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02012363 0,03141344 ! cilium assembly GO:0042384 38 19 0,000 0,02012363 0,03139338 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02012363 0,03137334 ! protein secretion GO:0009306 45 20 0,000 0,02117177 0,03298638 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02117177 0,03296536 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02117177 0,03294436 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02117177 0,03292339 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02117177 0,03290244 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,02117177 0,03288153 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02117177 0,03286064 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02117177 0,03283977 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02117177 0,03281894 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,02117177 0,03279812 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02117177 0,03277734 ! response to vitamin GO:0033273 36 20 0,000 0,02117177 0,03275658 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02117177 0,03273585 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,02117177 0,03271514 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02117177 0,03269446 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02117177 0,03267381 ! response to alkaloid GO:0043279 38 20 0,000 0,02117177 0,03265318 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02117177 0,03263258 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02117177 0,03261201 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02117177 0,03259146 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02117177 0,03257093 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,02117177 0,03255044 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,02117177 0,03252996 ! actin filament bundle formation GO:0051017 47 20 0,000 0,02117177 0,03250952 ! body fluid secretion GO:0007589 33 20 0,000 0,02117177 0,0324891 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02117177 0,0324687 ! peptide secretion GO:0002790 38 20 0,000 0,02117177 0,03244833 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02117177 0,03242799 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,02117177 0,03240767 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02117177 0,03238738 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02117177 0,03236711 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02117177 0,03234687 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02117177 0,03232665 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02117177 0,03230646 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02117177 0,03228629 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02117177 0,03226615 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02117177 0,03224604 ! regulation of glucose import GO:0046324 30 20 0,000 0,02117177 0,03222595 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02117177 0,03220588 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02117177 0,03218584 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02117177 0,03216582 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02117177 0,03214583 ! regulation of cell killing GO:0031341 46 21 0,000 0,02221883 0,03371465 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02221883 0,03369372 ! hormone secretion GO:0046879 39 21 0,000 0,02221883 0,03367282 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02221883 0,03365195 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02221883 0,0336311 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02221883 0,03361027 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,02221883 0,03358947 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02221883 0,0335687 ! ovarian follicle development GO:0001541 39 21 0,000 0,02221883 0,03354795 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02221883 0,03352723 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02221883 0,03350654 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02221883 0,03348587 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02221883 0,03346522 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02221883 0,0334446 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02221883 0,03342401 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02221883 0,03340344 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02221883 0,0333829 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02221883 0,03336238 ! sensory perception of pain GO:0019233 33 21 0,000 0,02221883 0,03334189 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02221883 0,03332142 ! diencephalon development GO:0021536 36 21 0,000 0,02221883 0,03330098 ! collagen fibril organization GO:0030199 62 21 0,000 0,02221883 0,03328056 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02221883 0,03326017 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02221883 0,0332398 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02221883 0,03321946 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02221883 0,03319914 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02221883 0,03317885 ! collagen catabolic process GO:0030574 29 21 0,000 0,02221883 0,03315858 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02221883 0,03313833 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02221883 0,03311812 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02221883 0,03309792 ! actin filament-based movement GO:0030048 47 21 0,000 0,02221883 0,03307775 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02221883 0,03305761 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02326479 0,03459274 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02326479 0,0345717 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02326479 0,03455068 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02326479 0,03452969 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,02326479 0,03450873 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02326479 0,03448779 ! microtubule-based transport GO:0010970 59 22 0,000 0,02326479 0,03446687 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02326479 0,03444598 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02326479 0,03442512 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,02326479 0,03440428 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,02326479 0,03438347 ! cellular response to starvation GO:0009267 37 22 0,000 0,02326479 0,03436268 ! vacuolar transport GO:0007034 41 22 0,000 0,02326479 0,03434192 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02326479 0,03432118 ! fucose metabolic process GO:0006004 44 22 0,000 0,02326479 0,03430047 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,02326479 0,03427978 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02326479 0,03425912 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,02326479 0,03423848 ! ureteric bud development GO:0001657 50 22 0,000 0,02326479 0,03421787 ! cell aging GO:0007569 48 22 0,000 0,02326479 0,03419728 ! stem cell differentiation GO:0048863 57 22 0,000 0,02326479 0,03417671 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02326479 0,03415617 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02326479 0,03413566 ! cytolysis GO:0019835 27 22 0,000 0,02326479 0,03411517 ! renal system process GO:0003014 42 22 0,000 0,02326479 0,03409471 ! vasodilation GO:0042311 40 22 0,000 0,02326479 0,03407427 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02326479 0,03405385 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02326479 0,03403346 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,02326479 0,03401309 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02326479 0,03399275 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02326479 0,03397243 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,02326479 0,03395214 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,02326479 0,03393187 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,02326479 0,03391162 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02326479 0,0338914 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02326479 0,0338712 ! sarcomere organization GO:0045214 32 22 0,000 0,02326479 0,03385103 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,02326479 0,03383088 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02326479 0,03381075 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02326479 0,03379065 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02326479 0,03377057 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02326479 0,03375052 ! gut development GO:0048565 44 22 0,000 0,02326479 0,03373049 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02326479 0,03371048 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,02326479 0,0336905 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02326479 0,03367054 ! protein stabilization GO:0050821 41 22 0,000 0,02326479 0,03365061 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,02430966 0,03514112 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,02430966 0,03512034 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,02430966 0,03509958 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,02430966 0,03507885 ! gluconeogenesis GO:0006094 38 23 0,000 0,02430966 0,03505814 ! glycerol metabolic process GO:0006071 40 23 0,000 0,02430966 0,03503746 ! viral genome replication GO:0019079 44 23 0,000 0,02430966 0,0350168 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,02430966 0,03499617 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,02430966 0,03497556 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,02430966 0,03495497 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,02430966 0,03493441 ! regeneration GO:0031099 42 23 0,000 0,02430966 0,03491387 ! axis specification GO:0009798 43 23 0,000 0,02430966 0,03489336 ! visual behavior GO:0007632 46 23 0,000 0,02430966 0,03487287 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,02430966 0,0348524 ! response to ethanol GO:0045471 47 23 0,000 0,02430966 0,03483196 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,02430966 0,03481155 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,02430966 0,03479115 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,02430966 0,03477078 ! peroxisome organization GO:0007031 43 23 0,000 0,02430966 0,03475044 ! lysosome organization GO:0007040 47 23 0,000 0,02430966 0,03473011 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,02430966 0,03470982 ! vesicle targeting GO:0006903 49 23 0,000 0,02430966 0,03468954 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,02430966 0,03466929 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,02430966 0,03464906 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,02430966 0,03462886 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,02430966 0,03460868 ! DNA modification GO:0006304 36 23 0,000 0,02430966 0,03458852 ! fatty acid transport GO:0015908 47 23 0,000 0,02430966 0,03456839 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,02430966 0,03454828 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,02430966 0,0345282 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,02430966 0,03450813 ! hormone transport GO:0009914 41 23 0,000 0,02430966 0,03448809 ! cell-cell recognition GO:0009988 28 23 0,000 0,02430966 0,03446808 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,02430966 0,03444808 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,02430966 0,03442811 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,02430966 0,03440817 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,02535344 0,03586477 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,02535344 0,03584402 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,02535344 0,03582328 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,02535344 0,03580258 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,02535344 0,03578189 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,02535344 0,03576124 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,02535344 0,0357406 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,02535344 0,03571999 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,02535344 0,0356994 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,02535344 0,03567884 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,02535344 0,0356583 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,02535344 0,03563778 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,02535344 0,03561729 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,02535344 0,03559682 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,02535344 0,03557637 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,02535344 0,03555595 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,02535344 0,03553555 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,02535344 0,03551517 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,02535344 0,03549482 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,02535344 0,03547449 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,02535344 0,03545418 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,02535344 0,0354339 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,02535344 0,03541364 ! membrane depolarization GO:0051899 45 24 0,000 0,02535344 0,03539341 ! pallium development GO:0021543 56 24 0,000 0,02535344 0,03537319 ! oogenesis GO:0048477 44 24 0,000 0,02535344 0,035353 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,02535344 0,03533283 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,02535344 0,03531269 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,02535344 0,03529257 ! platelet activation GO:0030168 41 24 0,000 0,02535344 0,03527247 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,02535344 0,0352524 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,02535344 0,03523234 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,02535344 0,03521231 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,02535344 0,03519231 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,02535344 0,03517232 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,02535344 0,03515236 ! regulation of amine transport GO:0051952 41 24 0,000 0,02535344 0,03513242 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,02535344 0,03511251 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02639614 0,03653584 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,02639614 0,03651516 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02639614 0,03649449 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,02639614 0,03647385 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02639614 0,03645323 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02639614 0,03643264 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02639614 0,03641206 ! phototransduction GO:0007602 37 25 0,000 0,02639614 0,03639152 ! keratinization GO:0031424 37 25 0,000 0,02639614 0,03637099 ! vasculogenesis GO:0001570 49 25 0,000 0,02639614 0,03635049 ! vacuole organization GO:0007033 49 25 0,000 0,02639614 0,03633001 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02639614 0,03630955 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02639614 0,03628912 ! receptor metabolic process GO:0043112 53 25 0,000 0,02639614 0,03626871 ! chromosome condensation GO:0030261 48 25 0,000 0,02639614 0,03624832 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02639614 0,03622796 ! regulation of behavior GO:0050795 48 25 0,000 0,02639614 0,03620762 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02639614 0,0361873 ! interaction with host GO:0051701 66 25 0,000 0,02639614 0,036167 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02639614 0,03614673 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02639614 0,03612648 ! immunoglobulin production GO:0002377 62 25 0,000 0,02639614 0,03610625 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02639614 0,03608605 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,02639614 0,03606586 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02639614 0,0360457 ! liver development GO:0001889 55 25 0,000 0,02639614 0,03602557 ! protein tetramerization GO:0051262 57 25 0,000 0,02639614 0,03600545 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,02743775 0,03740537 ! myelination GO:0042552 50 26 0,000 0,02743775 0,03738451 ! initiation of viral infection GO:0019059 60 26 0,000 0,02743775 0,03736367 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,02743775 0,03734285 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,02743775 0,03732206 ! molting cycle process GO:0022404 52 26 0,000 0,02743775 0,03730129 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,02743775 0,03728054 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,02743775 0,03725982 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,02743775 0,03723912 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,02743775 0,03721844 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,02743775 0,03719779 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,02743775 0,03717716 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,02743775 0,03715655 ! digestive system process GO:0022600 49 26 0,000 0,02743775 0,03713597 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,02743775 0,0371154 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,02743775 0,03709486 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,02743775 0,03707435 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,02743775 0,03705385 ! osteoblast differentiation GO:0001649 63 26 0,000 0,02743775 0,03703338 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,02743775 0,03701293 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,02743775 0,03699251 ! negative regulation of cell development GO:0010721 83 26 0,000 0,02743775 0,0369721 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,02743775 0,03695172 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,02743775 0,03693136 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,02743775 0,03691102 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,02743775 0,03689071 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,02743775 0,03687042 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,02743775 0,03685015 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,02743775 0,0368299 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,02743775 0,03680968 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,02743775 0,03678947 ! blastocyst development GO:0001824 50 26 0,000 0,02743775 0,03676929 ! telomere organization GO:0032200 46 26 0,000 0,02743775 0,03674913 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,02743775 0,036729 ! neural tube closure GO:0001843 58 26 0,000 0,02743775 0,03670888 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,02743775 0,03668879 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,02743775 0,03666872 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02847827 0,0380385 ! embryonic pattern specification GO:0009880 49 27 0,000 0,02847827 0,03801772 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,02847827 0,03799695 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,02847827 0,03797621 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,02847827 0,03795549 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,02847827 0,0379348 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,02847827 0,03791413 ! iron ion transport GO:0006826 65 27 0,000 0,02847827 0,03789348 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,02847827 0,03787285 ! superoxide metabolic process GO:0006801 41 27 0,000 0,02847827 0,03785224 ! tube lumen formation GO:0035148 59 27 0,000 0,02847827 0,03783166 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,02847827 0,0378111 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,02847827 0,03779056 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,02847827 0,03777004 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,02847827 0,03774955 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,02847827 0,03772908 ! response to starvation GO:0042594 47 27 0,000 0,02847827 0,03770863 ! response to toxin GO:0009636 49 27 0,000 0,02847827 0,0376882 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,02847827 0,0376678 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,02847827 0,03764741 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,02847827 0,03762705 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,02847827 0,03760671 ! leukocyte proliferation GO:0070661 59 27 0,000 0,02847827 0,0375864 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,02847827 0,0375661 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,02951771 0,03891623 ! neuron fate commitment GO:0048663 52 28 0,000 0,02951771 0,03889524 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,02951771 0,03887427 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,02951771 0,03885333 ! protein amino acid acylation GO:0043543 59 28 0,000 0,02951771 0,03883241 ! vesicle docking GO:0048278 55 28 0,000 0,02951771 0,0388115 ! circadian rhythm GO:0007623 56 28 0,000 0,02951771 0,03879063 ! dendrite development GO:0016358 67 28 0,000 0,02951771 0,03876977 ! fat cell differentiation GO:0045444 57 28 0,000 0,02951771 0,03874894 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,02951771 0,03872813 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,02951771 0,03870734 ! base-excision repair GO:0006284 41 28 0,000 0,02951771 0,03868658 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,02951771 0,03866583 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,02951771 0,03864511 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,02951771 0,03862441 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,02951771 0,03860373 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,02951771 0,03858308 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,02951771 0,03856245 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,02951771 0,03854184 ! glutathione metabolic process GO:0006749 42 28 0,000 0,02951771 0,03852125 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,02951771 0,03850068 ! lipid oxidation GO:0034440 48 28 0,000 0,02951771 0,03848014 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,02951771 0,03845961 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,02951771 0,03843911 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,03055607 0,0397701 ! translational initiation GO:0006413 66 29 0,000 0,03055607 0,03974893 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03055607 0,03972777 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03055607 0,03970664 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03055607 0,03968553 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,03055607 0,03966444 ! autophagy GO:0006914 47 29 0,000 0,03055607 0,03964338 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03055607 0,03962234 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03055607 0,03960132 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03055607 0,03958032 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03055607 0,03955935 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,03055607 0,03953839 ! somitogenesis GO:0001756 52 29 0,000 0,03055607 0,03951746 ! synaptogenesis GO:0007416 46 29 0,000 0,03055607 0,03949655 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,03055607 0,03947567 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03055607 0,0394548 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03055607 0,03943396 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,03055607 0,03941314 ! phenol metabolic process GO:0018958 56 30 0,000 0,03159335 0,04072958 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03159335 0,0407081 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03159335 0,04068664 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03159335 0,0406652 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03159335 0,04064379 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03159335 0,0406224 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03159335 0,04060103 ! acute-phase response GO:0006953 50 30 0,000 0,03159335 0,04057968 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03159335 0,04055836 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03159335 0,04053705 ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,03159335 0,04051577 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,03159335 0,04049452 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03159335 0,04047328 ! cell fate determination GO:0001709 64 30 0,000 0,03159335 0,04045207 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03159335 0,04043088 ! phospholipid transport GO:0015914 65 30 0,000 0,03159335 0,04040971 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03159335 0,04038857 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03159335 0,04036744 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,03159335 0,04034634 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03159335 0,04032526 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03159335 0,0403042 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,03159335 0,04028317 ! regulation of coagulation GO:0050818 52 30 0,000 0,03159335 0,04026216 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,03262954 0,04156099 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,03262954 0,04153933 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,03262954 0,0415177 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,03262954 0,04149608 ! cell junction assembly GO:0034329 85 31 0,000 0,03262954 0,04147449 ! regulation of innate immune response GO:0045088 57 31 0,000 0,03262954 0,04145293 ! ovulation cycle process GO:0022602 55 31 0,000 0,03262954 0,04143138 ! peptide transport GO:0015833 60 31 0,000 0,03262954 0,04140986 ! male gonad development GO:0008584 56 31 0,000 0,03262954 0,04138836 ! iron ion homeostasis GO:0055072 60 31 0,000 0,03262954 0,04136688 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,03262954 0,04134542 ! detection of light stimulus GO:0009583 44 31 0,000 0,03262954 0,04132399 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,03262954 0,04130258 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,03262954 0,04128119 ! natural killer cell activation GO:0030101 50 31 0,000 0,03262954 0,04125982 ! ensheathment of neurons GO:0007272 64 31 0,000 0,03262954 0,04123848 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,03262954 0,04121715 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,03262954 0,04119585 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,03262954 0,04117457 ! response to heat GO:0009408 54 31 0,000 0,03262954 0,04115332 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,03262954 0,04113208 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,03366466 0,04241504 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,03366466 0,04239318 ! collagen metabolic process GO:0032963 49 32 0,000 0,03366466 0,04237134 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,03366466 0,04234952 ! spindle organization GO:0007051 50 32 0,000 0,03366466 0,04232772 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,03366466 0,04230595 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,03366466 0,0422842 ! metanephros development GO:0001656 81 32 0,000 0,03366466 0,04226247 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,03366466 0,04224076 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,03366466 0,04221908 ! mesoderm formation GO:0001707 73 32 0,000 0,03366466 0,04219742 ! ovulation cycle GO:0042698 57 32 0,000 0,03366466 0,04217578 ! peripheral nervous system development GO:0007422 68 32 0,000 0,03366466 0,04215416 ! BMP signaling pathway GO:0030509 71 32 0,000 0,03366466 0,04213256 ! hindbrain development GO:0030902 65 32 0,000 0,03366466 0,04211099 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,03366466 0,04208944 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,03366466 0,04206791 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,03366466 0,0420464 ! gene silencing GO:0016458 71 32 0,000 0,03366466 0,04202492 ! regulation of pH GO:0006885 56 33 0,000 0,0346987 0,04329363 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,0346987 0,04327153 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,0346987 0,04324945 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,0346987 0,04322739 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,0346987 0,04320536 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,0346987 0,04318335 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,0346987 0,04316136 ! response to ionizing radiation GO:0010212 74 33 0,000 0,0346987 0,0431394 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,0346987 0,04311746 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,0346987 0,04309554 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,0346987 0,04307364 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,0346987 0,04305176 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,0346987 0,04302991 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,0346987 0,04300808 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,0346987 0,04298627 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,03573166 0,04424351 ! glial cell differentiation GO:0010001 67 34 0,000 0,03573166 0,04422109 ! post-embryonic development GO:0009791 76 34 0,000 0,03573166 0,0441987 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,03573166 0,04417634 ! cholesterol transport GO:0030301 62 34 0,000 0,03573166 0,04415399 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,03573166 0,04413167 ! spliceosome assembly GO:0000245 75 34 0,000 0,03573166 0,04410937 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,03573166 0,04408709 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,03573166 0,04406484 ! formation of primary germ layer GO:0001704 76 34 0,000 0,03573166 0,0440426 ! cell fate specification GO:0001708 56 34 0,000 0,03573166 0,04402039 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,03573166 0,04399821 ! adult locomotory behavior GO:0008344 62 34 0,000 0,03573166 0,04397604 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,03573166 0,0439539 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,03676354 0,04520047 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,03676354 0,04517773 ! negative regulation of secretion GO:0051048 68 35 0,000 0,03676354 0,04515502 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,03676354 0,04513233 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,03676354 0,04510966 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,03676354 0,04508701 ! membrane docking GO:0022406 69 35 0,000 0,03676354 0,04506439 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,03676354 0,04504179 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,03676354 0,04501921 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,03676354 0,04499666 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,03676354 0,04497413 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,03676354 0,04495162 ! ceramide metabolic process GO:0006672 72 35 0,000 0,03676354 0,04492913 ! telencephalon development GO:0021537 81 35 0,000 0,03676354 0,04490667 ! sterol transport GO:0015918 63 35 0,000 0,03676354 0,04488422 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,03676354 0,04486181 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,03676354 0,04483941 ! placenta development GO:0001890 53 35 0,000 0,03676354 0,04481703 ! vesicle localization GO:0051648 70 35 0,000 0,03676354 0,04479468 ! regulation of muscle development GO:0048634 82 36 0,000 0,03779435 0,04602772 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,03779435 0,04600478 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,03779435 0,04598187 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,03779435 0,04595898 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,03779435 0,04593612 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,03779435 0,04591328 ! positive regulation of cell development GO:0010720 85 36 0,000 0,03779435 0,04589046 ! regulation of proteolysis GO:0030162 77 36 0,000 0,03779435 0,04586766 ! aerobic respiration GO:0009060 56 36 0,000 0,03779435 0,04584489 ! cytokine production GO:0001816 68 36 0,000 0,03779435 0,04582213 ! embryonic organ development GO:0048568 67 36 0,000 0,03779435 0,0457994 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,03779435 0,0457767 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,03882409 0,04700061 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,03882409 0,04697734 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,03882409 0,04695408 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,03882409 0,04693085 ! sister chromatid segregation GO:0000819 65 37 0,000 0,03882409 0,04690764 ! odontogenesis GO:0042476 74 37 0,000 0,03882409 0,04688445 ! tissue remodeling GO:0048771 78 37 0,000 0,03882409 0,04686128 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,03882409 0,04683814 ! female gonad development GO:0008585 71 37 0,000 0,03882409 0,04681503 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,03882409 0,04679193 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,03882409 0,04676886 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,03882409 0,04674581 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,03882409 0,04672278 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,03985275 0,04793711 ! meiosis I GO:0007127 74 38 0,000 0,03985275 0,04791351 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,03985275 0,04788995 ! organic anion transport GO:0015711 82 38 0,000 0,03985275 0,0478664 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,03985275 0,04784288 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,03985275 0,04781938 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,03985275 0,04779591 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,03985275 0,04777245 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,03985275 0,04774902 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,03985275 0,04772562 ! regulation of protein stability GO:0031647 77 38 0,000 0,03985275 0,04770223 ! spermatid development GO:0007286 69 38 0,000 0,03985275 0,04767887 ! glycogen metabolic process GO:0005977 63 38 0,000 0,03985275 0,04765554 ! pigment metabolic process GO:0042440 87 38 0,000 0,03985275 0,04763222 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,03985275 0,04760893 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,04088034 0,04881264 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,04088034 0,04878879 ! negative regulation of binding GO:0051100 71 39 0,000 0,04088034 0,04876497 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,04088034 0,04874117 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,04088034 0,0487174 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,04088034 0,04869364 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,04088034 0,04866991 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,04088034 0,04864621 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,04088034 0,04862252 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,04088034 0,04859886 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,04088034 0,04857522 ! glucan metabolic process GO:0044042 64 39 0,000 0,04088034 0,04855161 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,04190686 0,04974657 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,04190686 0,04972241 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,04190686 0,04969828 ! learning GO:0007612 82 40 0,000 0,04190686 0,04967416 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,04190686 0,04965007 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,04190686 0,049626 ! lipid homeostasis GO:0055088 75 40 0,000 0,04190686 0,04960196 ! mismatch repair GO:0006298 58 40 0,000 0,04190686 0,04957794 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,04190686 0,04955394 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,04190686 0,04952997 ! mRNA catabolic process GO:0006402 79 41 0,000 0,0429323 0,05071742 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,0429323 0,0506929 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,0429323 0,05066842 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,0429323 0,05064395 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,0429323 0,05061951 ! gliogenesis GO:0042063 91 41 0,000 0,0429323 0,05059509 ! feeding behavior GO:0007631 69 41 0,000 0,0429323 0,05057069 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,0429323 0,05054632 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,0429323 0,05052197 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,0429323 0,05049765 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,0429323 0,05047335 ! spermatid differentiation GO:0048515 73 41 0,000 0,0429323 0,05044907 ! RNA modification GO:0009451 64 41 0,000 0,0429323 0,05042482 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,04395668 0,05160316 ! ear morphogenesis GO:0042471 64 42 0,000 0,04395668 0,05157838 ! organic ether metabolic process GO:0018904 59 42 0,000 0,04395668 0,05155362 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,04395668 0,05152888 ! T cell differentiation GO:0030217 93 42 0,000 0,04395668 0,05150416 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,04395668 0,05147947 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,04395668 0,05145481 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,04395668 0,05143016 ! regulation of protein secretion GO:0050708 77 42 0,000 0,04395668 0,05140554 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,04395668 0,05138095 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,04395668 0,05135638 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,04498 0,05252683 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,04498 0,05250174 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,04498 0,05247666 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,04498 0,05245161 ! regulation of tube size GO:0035150 76 43 0,000 0,04498 0,05242659 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,04498 0,05240159 ! glucose transport GO:0015758 66 43 0,000 0,04498 0,05237661 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,04498 0,05235166 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,04498 0,05232673 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,04498 0,05230182 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,04498 0,05227694 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,04498 0,05225208 ! segmentation GO:0035282 78 43 0,000 0,04498 0,05222725 ! ion transmembrane transport GO:0034220 79 43 0,000 0,04498 0,05220244 ! neuron migration GO:0001764 85 43 0,000 0,04498 0,05217765 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,04498 0,05215289 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,04600224 0,05331285 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,04600224 0,05328757 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,04600224 0,05326231 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,04600224 0,05323708 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,04600224 0,05321188 ! hexose transport GO:0008645 68 44 0,000 0,04600224 0,05318669 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,04600224 0,05316153 ! striated muscle contraction GO:0006941 85 44 0,000 0,04600224 0,0531364 ! phagocytosis GO:0006909 105 44 0,000 0,04600224 0,05311129 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,04600224 0,0530862 ! double-strand break repair GO:0006302 85 44 0,000 0,04600224 0,05306113 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,04702342 0,05421341 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,04702342 0,05418784 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,04702342 0,05416229 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,04702342 0,05413677 ! B cell differentiation GO:0030183 124 45 0,000 0,04702342 0,05411127 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,04702342 0,05408579 ! female gamete generation GO:0007292 71 45 0,000 0,04702342 0,05406034 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,04702342 0,05403491 ! developmental growth GO:0048589 88 45 0,000 0,04702342 0,05400951 ! maintenance of location in cell GO:0051651 101 45 0,000 0,04702342 0,05398413 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,04804354 0,05512934 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,04804354 0,05510346 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,04804354 0,0550776 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,04804354 0,05505177 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,04804354 0,05502596 ! leukocyte migration GO:0050900 75 46 0,000 0,04804354 0,05500017 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,04804354 0,05497441 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,04804354 0,05494867 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,04804354 0,05492296 ! pigmentation GO:0043473 103 46 0,000 0,04804354 0,05489727 ! cell growth GO:0016049 90 46 0,000 0,04804354 0,05487161 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,04804354 0,05484597 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,04906259 0,05598315 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,05008058 0,05711805 ! positive regulation of defense response GO:0031349 88 48 0,000 0,05008058 0,0570914 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,05008058 0,05706477 ! mitochondrial transport GO:0006839 94 48 0,000 0,05008058 0,05703817 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,05008058 0,05701159 ! cellular component disassembly GO:0022411 89 48 0,000 0,05008058 0,05698503 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,05008058 0,0569585 ! endosome transport GO:0016197 127 48 0,000 0,05008058 0,056932 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,05008058 0,05690552 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,05008058 0,05687906 ! male sex differentiation GO:0046661 93 48 0,000 0,05008058 0,05685263 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,05008058 0,05682623 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,05008058 0,05679985 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,05008058 0,05677349 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,05008058 0,05674716 ! methylation GO:0032259 97 48 0,000 0,05008058 0,05672085 ! response to calcium ion GO:0051592 94 49 0,000 0,05109751 0,0578458 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,05109751 0,057819 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,05109751 0,05779223 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,05109751 0,05776549 ! JNK cascade GO:0007254 106 49 0,000 0,05109751 0,05773877 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,05109751 0,05771208 ! protein homooligomerization GO:0051260 84 49 0,000 0,05109751 0,05768541 ! regulation of action potential GO:0001508 102 50 0,000 0,05211338 0,05880508 ! regulation of ion transport GO:0043269 86 50 0,000 0,05211338 0,05877793 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,05211338 0,05875081 ! endocrine system development GO:0035270 109 50 0,000 0,05211338 0,05872371 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,05211338 0,05869663 ! activation of caspase activity GO:0006919 95 50 0,000 0,05211338 0,05866958 ! regulation of ossification GO:0030278 123 50 0,000 0,05211338 0,05864256 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,05211338 0,05861556 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,05211338 0,05858859 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,05211338 0,05856164 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,05211338 0,05853471 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,05312819 0,05964714 ! viral infectious cycle GO:0019058 104 51 0,000 0,05312819 0,05961974 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,05312819 0,05959237 ! peptide metabolic process GO:0006518 80 51 0,000 0,05312819 0,05956502 ! response to temperature stimulus GO:0009266 84 51 0,000 0,05312819 0,0595377 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,05312819 0,0595104 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,05312819 0,05948313 ! positive regulation of binding GO:0051099 88 52 0,000 0,05414195 0,06059037 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,05414195 0,06056263 ! Notch signaling pathway GO:0007219 111 52 0,000 0,05414195 0,06053491 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,05414195 0,06050722 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,05414195 0,06047955 ! excretion GO:0007588 87 52 0,000 0,05414195 0,06045191 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,05414195 0,06042429 ! histone modification GO:0016570 104 52 0,000 0,05414195 0,0603967 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,05414195 0,06036914 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,05414195 0,0603416 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,05414195 0,06031408 ! amino acid activation GO:0043038 98 52 0,000 0,05414195 0,06028659 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,05515464 0,06138624 ! inner ear development GO:0048839 89 53 0,000 0,05515464 0,06135828 ! chromatin remodeling GO:0006338 122 53 0,000 0,05515464 0,06133036 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,05515464 0,06130245 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,05515464 0,06127458 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,05515464 0,06124672 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,05515464 0,0612189 ! cartilage development GO:0051216 99 53 0,000 0,05515464 0,0611911 ! synapse organization GO:0050808 102 53 0,000 0,05515464 0,06116332 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,05616628 0,06225691 ! regulation of translational initiation GO:0006446 87 54 0,000 0,05616628 0,06222868 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,05616628 0,06220047 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,05616628 0,06217228 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,05616628 0,06214413 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,05616628 0,06211599 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,05616628 0,06208789 ! membrane fusion GO:0006944 122 54 0,000 0,05616628 0,06205981 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,05616628 0,06203175 ! covalent chromatin modification GO:0016569 115 54 0,000 0,05616628 0,06200372 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,05616628 0,06197571 ! regulation of cell shape GO:0008360 142 54 0,000 0,05616628 0,06194773 ! RNA catabolic process GO:0006401 103 55 0,000 0,05717687 0,06303389 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,05717687 0,06300545 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,05717687 0,06297705 ! cell recognition GO:0008037 98 55 0,000 0,05717687 0,06294867 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,05717687 0,06292031 ! cell maturation GO:0048469 107 55 0,000 0,05717687 0,06289198 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,05717687 0,06286368 ! response to UV GO:0009411 120 55 0,000 0,05717687 0,0628354 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,05717687 0,06280715 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,0581864 0,06388736 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,0581864 0,06385866 ! regulation of DNA replication GO:0006275 105 56 0,000 0,0581864 0,06382999 ! RNA elongation GO:0006354 90 56 0,000 0,0581864 0,06380134 ! chloride transport GO:0006821 102 57 0,000 0,05919488 0,06487801 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,05919488 0,06484892 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,05919488 0,06481985 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,05919488 0,06479081 ! heart morphogenesis GO:0003007 105 57 0,000 0,05919488 0,0647618 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,05919488 0,06473281 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,05919488 0,06470384 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,06020231 0,0657756 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,06020231 0,0657462 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,06020231 0,06571682 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,06020231 0,06568747 ! aging GO:0007568 112 58 0,000 0,06020231 0,06565814 ! gastrulation GO:0007369 122 58 0,000 0,06020231 0,06562884 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,06020231 0,06559957 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,06020231 0,06557033 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,06020231 0,0655411 ! maintenance of location GO:0051235 124 58 0,000 0,06020231 0,06551191 ! establishment of organelle localization GO:0051656 122 59 0,000 0,06120869 0,06657739 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,06221401 0,06764078 ! lipid modification GO:0030258 112 60 0,000 0,06221401 0,06761069 ! DNA catabolic process GO:0006308 94 60 0,000 0,06221401 0,06758063 ! regulation of endocytosis GO:0030100 104 60 0,000 0,06221401 0,06755059 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,06221401 0,06752058 ! adult behavior GO:0030534 104 60 0,000 0,06221401 0,0674906 ! kidney development GO:0001822 133 60 0,000 0,06221401 0,06746065 ! positive regulation of secretion GO:0051047 110 61 0,000 0,06321829 0,06851921 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,06321829 0,06848882 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,06321829 0,06845846 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,06321829 0,06842813 ! regulation of heart contraction GO:0008016 123 61 0,000 0,06321829 0,06839783 ! camera-type eye development GO:0043010 126 61 0,000 0,06321829 0,06836755 ! proton transport GO:0015992 117 61 0,000 0,06321829 0,0683373 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,06321829 0,06830707 ! viral reproductive process GO:0022415 132 62 0,000 0,06422153 0,06936038 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,06422153 0,06932973 ! tRNA processing GO:0008033 102 62 0,000 0,06422153 0,06929911 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,06422153 0,06926852 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,06522371 0,07031842 ! regulation of mitosis GO:0007088 112 63 0,000 0,06522371 0,0702874 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,06522371 0,07025641 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,06522371 0,07022544 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,06522371 0,07019451 ! hydrogen transport GO:0006818 121 64 0,000 0,06622485 0,07124056 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,06622485 0,07120921 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,06622485 0,07117788 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,06622485 0,07114658 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,06722495 0,07218926 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,06722495 0,07215754 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,06722495 0,07212585 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,06722495 0,07209419 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,06722495 0,07206255 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,06722495 0,07203095 ! ear development GO:0043583 114 66 0,000 0,06822401 0,07306938 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,06822401 0,07303736 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,06822401 0,07300536 ! gonad development GO:0008406 115 66 0,000 0,06822401 0,0729734 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,06822401 0,07294146 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,06922202 0,07397611 ! activation of MAPK activity GO:0000187 124 67 0,000 0,06922202 0,07394377 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,06922202 0,07391145 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,06922202 0,07387916 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,06922202 0,0738469 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,06922202 0,07381466 ! secondary metabolic process GO:0019748 125 67 0,000 0,06922202 0,07378246 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,06922202 0,07375028 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,07021899 0,07477986 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,07021899 0,07474727 ! extracellular matrix organization GO:0030198 146 68 0,000 0,07021899 0,07471472 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,07021899 0,07468219 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,07021899 0,07464969 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,07021899 0,07461722 ! regulation of lipase activity GO:0060191 137 68 0,000 0,07021899 0,07458478 ! adaptive immune response GO:0002250 126 68 0,000 0,07021899 0,07455237 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell size GO:0045792 144 69 0,000 0,07121492 0,07557691 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,07121492 0,0755441 ! lung development GO:0030324 165 69 0,000 0,07121492 0,07551131 ! urogenital system development GO:0001655 149 69 0,000 0,07121492 0,07547855 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,07121492 0,07544582 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,07121492 0,07541311 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,07121492 0,07538044 ! developmental maturation GO:0021700 128 69 0,000 0,07121492 0,07534779 ! single fertilization GO:0007338 83 69 0,000 0,07121492 0,07531518 ! cell redox homeostasis GO:0045454 114 70 0,000 0,07220982 0,0763343 ! germ cell development GO:0007281 133 70 0,000 0,07220982 0,07630129 ! activation of immune response GO:0002253 120 70 0,000 0,07220982 0,0762683 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,07220982 0,07623534 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,07320367 0,07725122 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,07320367 0,07721786 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,07320367 0,07718454 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,07320367 0,07715124 ! appendage morphogenesis GO:0035107 150 72 0,000 0,07419649 0,07816387 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,07419649 0,07813018 ! respiratory tube development GO:0030323 171 72 0,000 0,07419649 0,07809652 ! B cell activation GO:0042113 179 72 0,000 0,07419649 0,07806289 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,07419649 0,07802928 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,07419649 0,07799571 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,07419649 0,07796216 ! appendage development GO:0048736 151 73 0,000 0,07518827 0,07897031 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,07518827 0,07893638 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,07518827 0,07890247 ! regulation of immune effector process GO:0002697 156 73 0,000 0,07518827 0,07886859 ! acute inflammatory response GO:0002526 118 74 0,000 0,07617902 0,07987354 ! amino acid transport GO:0006865 148 74 0,000 0,07617902 0,07983927 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,07617902 0,07980504 ! respiratory system development GO:0060541 175 74 0,000 0,07617902 0,07977083 ! organelle localization GO:0051640 155 74 0,000 0,07617902 0,07973665 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,07716874 0,080738 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,07716874 0,08070343 ! reproductive structure development GO:0048608 131 75 0,000 0,07716874 0,0806689 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,07716874 0,0806344 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,07716874 0,08059992 ! rhythmic process GO:0048511 142 75 0,000 0,07716874 0,08056548 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,07815742 0,08156283 ! learning or memory GO:0007611 161 76 0,000 0,07815742 0,081528 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,07815742 0,0814932 ! regulation of blood pressure GO:0008217 134 76 0,000 0,07815742 0,08145844 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,07815742 0,0814237 ! amine catabolic process GO:0009310 136 77 0,000 0,07914507 0,08241748 ! neurotransmitter transport GO:0006836 142 77 0,000 0,07914507 0,08238236 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,07914507 0,08234728 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,07914507 0,08231222 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,07914507 0,08227719 ! regulation of catabolic process GO:0009894 173 77 0,000 0,07914507 0,0822422 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,08013169 0,08323202 ! antigen processing and presentation GO:0019882 117 78 0,000 0,08013169 0,08319665 ! fertilization GO:0009566 99 78 0,000 0,08013169 0,08316131 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,08013169 0,083126 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,08111728 0,0841127 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,08111728 0,08407701 ! protein oligomerization GO:0051259 149 79 0,000 0,08111728 0,08404136 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,08111728 0,08400573 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,08210185 0,08498933 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,08210185 0,08495333 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,08210185 0,08491736 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,08210185 0,08488143 ! meiosis GO:0007126 143 81 0,000 0,08308538 0,08586193 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 0,000 0,08308538 0,08582562 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,08308538 0,08578935 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,08308538 0,0857531 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,08406789 0,08673052 ! protein import into nucleus GO:0006606 174 82 0,000 0,08406789 0,08669391 ! meiotic cell cycle GO:0051321 144 82 0,000 0,08406789 0,08665733 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,08504938 0,08763207 ! exocytosis GO:0006887 153 83 0,000 0,08504938 0,08759512 ! response to drug GO:0042493 149 83 0,000 0,08504938 0,08755821 ! response to oxygen levels GO:0070482 183 83 0,000 0,08504938 0,08752133 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,08504938 0,08748448 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,08504938 0,08744766 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,08504938 0,08741087 ! nuclear import GO:0051170 177 83 0,000 0,08504938 0,08737411 ! inorganic anion transport GO:0015698 156 83 0,000 0,08504938 0,08733738 ! response to metal ion GO:0010038 158 84 0,000 0,08602984 0,0883071 ! T cell activation GO:0042110 189 84 0,000 0,08602984 0,08827001 ! response to nutrient GO:0007584 135 84 0,000 0,08602984 0,08823295 ! digestion GO:0007586 130 84 0,000 0,08602984 0,08819593 ! negative regulation of transport GO:0051051 164 85 0,000 0,08700928 0,08916261 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,08700928 0,08912523 ! negative regulation of growth GO:0045926 168 85 0,000 0,08700928 0,08908787 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,08700928 0,08905055 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,08700928 0,08901326 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,08700928 0,088976 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,08700928 0,08893877 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,08798769 0,08990127 ! regulation of lyase activity GO:0051339 169 86 0,000 0,08798769 0,08986368 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,08798769 0,08982613 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,08896509 0,09078601 ! nucleosome assembly GO:0006334 126 87 0,000 0,08896509 0,0907481 ! regulation of protein transport GO:0051223 165 87 0,000 0,08896509 0,09071023 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 0,000 0,08994146 0,0916675 ! sensory perception of smell GO:0007608 117 88 0,000 0,08994146 0,09162927 ! chromatin assembly GO:0031497 128 88 0,000 0,08994146 0,09159108 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,08994146 0,09155291 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,09091682 0,0925072 ! regulation of DNA binding GO:0051101 167 89 0,000 0,09091682 0,09246869 ! cellular defense response GO:0006968 123 89 0,000 0,09091682 0,09243021 ! protein localization in nucleus GO:0034504 192 89 0,000 0,09091682 0,09239176 ! regulation of neurological system process GO:0031644 175 89 0,000 0,09091682 0,09235334 ! response to inorganic substance GO:0010035 173 90 0,000 0,09189116 0,09330428 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,09189116 0,09326552 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,09189116 0,09322678 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,09189116 0,09318808 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,09286448 0,09413607 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,09286448 0,09409702 ! gland development GO:0048732 220 91 0,000 0,09286448 0,09405801 ! defense response to bacterium GO:0042742 112 91 0,000 0,09286448 0,09401903 ! bone development GO:0060348 206 92 0,000 0,09383678 0,09496407 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,09383678 0,09492475 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,09480807 0,0958676 ! amine transport GO:0015837 181 93 0,000 0,09480807 0,09582794 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,09480807 0,09578831 ! vitamin metabolic process GO:0006766 153 93 0,000 0,09480807 0,09574871 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,09577835 0,09668864 ! female pregnancy GO:0007565 166 94 0,000 0,09577835 0,0966487 ! sterol metabolic process GO:0016125 166 94 0,000 0,09577835 0,0966088 ! regulation of membrane potential GO:0042391 179 94 0,000 0,09577835 0,09656893 ! regulation of defense response GO:0031347 171 95 0,000 0,09674762 0,09750595 ! nucleosome organization GO:0034728 143 95 0,000 0,09674762 0,09746574 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,09674762 0,09742557 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,09674762 0,09738542 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,09674762 0,09734532 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,09674762 0,09730524 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,09674762 0,0972652 ! sex differentiation GO:0007548 171 96 0,000 0,09771587 0,09819822 ! regulation of T cell activation GO:0050863 175 96 0,000 0,09771587 0,09815784 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,09868311 0,09908871 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,09868311 0,099048 ! transcription initiation GO:0006352 171 97 0,000 0,09868311 0,09900733 ! regulation of protein localization GO:0032880 188 97 0,000 0,09868311 0,09896668 ! leukocyte differentiation GO:0002521 232 98 0,000 0,09964934 0,09989468 ! interphase of mitotic cell cycle GO:0051329 224 98 0,000 0,09964934 0,09985371 ! forebrain development GO:0030900 210 98 0,000 0,09964934 0,09981277 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,09964934 0,09977186 ! mRNA transport GO:0051028 185 100 0,000 0,10157878 0,10166201 ! positive regulation of immune response GO:0050778 175 100 0,000 0,10157878 0,10162038 ! hormone metabolic process GO:0042445 171 100 0,000 0,10157878 0,10157878