pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/9054-10-real-Parker_GPL1390-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL1390.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 2,306E-08 8,235E-05 ! skin development GO:0043588 16 15 2,000 1,868E-07 3,335E-04 ! replication fork GO:0005657 32 31 2,000 1,832E-06 2,18E-03 ! embryonic camera-type eye development GO:0031076 7 5 1,000 6,073E-06 5,421E-03 GO:0048596|embryonic camera-type eye morphogenesis, ! MutLalpha complex binding GO:0032405 6 5 1,000 6,073E-06 4,337E-03 ! phosphatidylserine binding GO:0001786 5 5 1,000 6,073E-06 3,614E-03 ! ribonuclease H activity GO:0004523 5 5 1,000 6,073E-06 3,098E-03 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 5 5 1,000 6,073E-06 2,711E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 6,073E-06 2,409E-03 ! metallo-sulfur cluster assembly GO:0031163 5 5 1,000 6,073E-06 2,169E-03 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of protein ubiquitination GO:0031397 5 5 1,000 6,073E-06 1,971E-03 ! 5'-3' exonuclease activity GO:0008409 5 5 1,000 6,073E-06 1,807E-03 ! response to UV GO:0009411 50 49 2,000 7,446E-06 2,045E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 51 50 2,000 7,918E-06 2,02E-03 ! regulation of DNA replication GO:0006275 56 50 2,000 7,918E-06 1,885E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 9,105E-06 2,032E-03 ! cysteine metabolic process GO:0006534 6 6 1,000 9,105E-06 1,913E-03 ! enucleate erythrocyte differentiation GO:0043353 6 6 1,000 9,105E-06 1,806E-03 ! DNA replication factor C complex GO:0005663 6 6 1,000 9,105E-06 1,711E-03 ! exodeoxyribonuclease activity GO:0004529 6 6 1,000 9,105E-06 1,626E-03 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! definitive hemopoiesis GO:0060216 6 6 1,000 9,105E-06 1,548E-03 ! embryonic skeletal system development GO:0048706 54 53 2,000 9,45E-06 1,534E-03 ! double-stranded DNA binding GO:0003690 55 54 2,000 1E-05 1,553E-03 ! response to peptide hormone stimulus GO:0043434 60 55 2,000 1,057E-05 1,573E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 7 7 1,000 1,274E-05 1,82E-03 GO:0010921|regulation of phosphatase activity, ! regulation of focal adhesion formation GO:0051893 9 7 1,000 1,274E-05 1,75E-03 ! protein kinase regulator activity GO:0019887 64 64 2,000 1,672E-05 2,212E-03 ! negative regulation of lipid biosynthetic process GO:0051055 9 8 1,000 1,698E-05 2,166E-03 ! regulation of smooth muscle cell migration GO:0014910 9 8 1,000 1,698E-05 2,091E-03 ! keratinocyte proliferation GO:0043616 8 8 1,000 1,698E-05 2,021E-03 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,698E-05 1,956E-03 ! embryonic eye morphogenesis GO:0048048 10 8 1,000 1,698E-05 1,895E-03 ! platelet-derived growth factor binding GO:0048407 10 9 1,000 2,182E-05 2,361E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 9 1,000 2,182E-05 2,292E-03 ! trophectodermal cell differentiation GO:0001829 9 9 1,000 2,182E-05 2,226E-03 ! response to inorganic substance GO:0010035 74 70 2,000 2,191E-05 2,173E-03 ! phosphoinositide-mediated signaling GO:0048015 79 75 2,000 2,697E-05 2,603E-03 ! regulation of dephosphorylation GO:0035303 12 10 1,000 2,726E-05 2,562E-03 ! mismatch repair complex binding GO:0032404 11 10 1,000 2,726E-05 2,496E-03 ! positive regulation of endothelial cell proliferation GO:0001938 11 10 1,000 2,726E-05 2,434E-03 ! regulation of stress fiber formation GO:0051492 13 10 1,000 2,726E-05 2,375E-03 ! kinase regulator activity GO:0019207 77 77 2,000 2,919E-05 2,481E-03 ! regulation of DNA metabolic process GO:0051052 90 80 2,000 3,274E-05 2,719E-03 ! blastocyst formation GO:0001825 11 11 1,000 3,331E-05 2,703E-03 ! regulation of actin filament bundle formation GO:0032231 14 11 1,000 3,331E-05 2,643E-03 ! substrate-bound cell migration GO:0006929 11 11 1,000 3,331E-05 2,586E-03 ! UV protection GO:0009650 11 11 1,000 3,331E-05 2,531E-03 ! cyclin-dependent protein kinase regulator activity GO:0016538 11 11 1,000 3,331E-05 2,478E-03 ! ossification GO:0001503 85 81 2,000 3,398E-05 2,476E-03 ! bone development GO:0060348 86 82 2,000 3,525E-05 2,518E-03 ! negative regulation of lipid metabolic process GO:0045833 13 12 1,000 3,995E-05 2,797E-03 ! positive regulation of Ras GTPase activity GO:0032320 12 12 1,000 3,995E-05 2,744E-03 ! fibrillar collagen GO:0005583 13 12 1,000 3,995E-05 2,692E-03 ! response to cAMP GO:0051591 12 12 1,000 3,995E-05 2,642E-03 ! negative regulation of caspase activity GO:0043154 12 12 1,000 3,995E-05 2,594E-03 ! positive regulation of GTPase activity GO:0043547 14 13 1,000 4,719E-05 3,01E-03 ! positive regulation of cell growth GO:0030307 13 13 1,000 4,719E-05 2,957E-03 ! embryonic placenta development GO:0001892 13 13 1,000 4,719E-05 2,906E-03 ! regulation of protein ubiquitination GO:0031396 13 13 1,000 4,719E-05 2,856E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 15 13 1,000 4,719E-05 2,809E-03 ! histone deacetylation GO:0016575 13 13 1,000 4,719E-05 2,763E-03 ! structure-specific DNA binding GO:0043566 93 92 2,000 4,976E-05 2,866E-03 ! protein serine/threonine kinase inhibitor activity GO:0030291 14 14 1,000 5,504E-05 3,12E-03 ! negative regulation of blood coagulation GO:0030195 16 14 1,000 5,504E-05 3,071E-03 ! release of cytochrome c from mitochondria GO:0001836 14 14 1,000 5,504E-05 3,024E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 14 14 1,000 5,504E-05 2,978E-03 ! negative regulation of peptidase activity GO:0010466 16 15 1,000 6,347E-05 3,383E-03 ! platelet-derived growth factor receptor binding GO:0005161 16 15 1,000 6,347E-05 3,333E-03 ! positive regulation of cell size GO:0045793 16 16 1,000 7,251E-05 3,753E-03 ! biomineral formation GO:0031214 16 16 1,000 7,251E-05 3,699E-03 ! negative regulation of coagulation GO:0050819 18 16 1,000 7,251E-05 3,647E-03 ! epidermis morphogenesis GO:0048730 16 16 1,000 7,251E-05 3,596E-03 ! regulation of lipid biosynthetic process GO:0046890 18 17 1,000 8,214E-05 4,018E-03 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 17 17 1,000 8,214E-05 3,964E-03 ! protein amino acid deacetylation GO:0006476 17 17 1,000 8,214E-05 3,911E-03 ! regulation of Rho GTPase activity GO:0032319 17 17 1,000 8,214E-05 3,859E-03 ! endodeoxyribonuclease activity GO:0004520 17 17 1,000 8,214E-05 3,809E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 18 17 1,000 8,214E-05 3,761E-03 ! chaperone binding GO:0051087 18 18 1,000 9,237E-05 4,175E-03 ! negative regulation of translation GO:0017148 20 18 1,000 9,237E-05 4,123E-03 ! histone deacetylase activity GO:0004407 19 18 1,000 9,237E-05 4,072E-03 GO:0033558|protein deacetylase activity, ! cellular response to unfolded protein GO:0034620 21 19 1,000 1,032E-04 4,494E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! nuclear inner membrane GO:0005637 20 20 1,000 1,146E-04 4,93E-03 ! positive regulation of locomotion GO:0040017 20 20 1,000 1,146E-04 4,872E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of blood coagulation GO:0030193 22 20 1,000 1,146E-04 4,814E-03 ! embryonic organ morphogenesis GO:0048562 22 20 1,000 1,146E-04 4,758E-03 ! liver development GO:0001889 20 20 1,000 1,146E-04 4,704E-03 ! regulation of cell-matrix adhesion GO:0001952 22 20 1,000 1,146E-04 4,65E-03 GO:0010810|regulation of cell-substrate adhesion, ! apoptotic mitochondrial changes GO:0008637 21 21 1,000 1,266E-04 5,08E-03 ! regulation of endothelial cell migration GO:0010594 21 21 1,000 1,266E-04 5,023E-03 ! deacetylase activity GO:0019213 22 21 1,000 1,266E-04 4,968E-03 ! collagen fibril organization GO:0030199 22 21 1,000 1,266E-04 4,914E-03 ! positive regulation of fibroblast proliferation GO:0048146 22 21 1,000 1,266E-04 4,861E-03 ! sulfur amino acid metabolic process GO:0000096 22 21 1,000 1,266E-04 4,81E-03 ! regulation of chemotaxis GO:0050920 21 21 1,000 1,266E-04 4,759E-03 ! base-excision repair GO:0006284 21 21 1,000 1,266E-04 4,709E-03 ! positive regulation of DNA replication GO:0045740 23 22 1,000 1,392E-04 5,125E-03 ! positive regulation of cell adhesion GO:0045785 23 22 1,000 1,392E-04 5,072E-03 ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 22 22 1,000 1,392E-04 5,021E-03 ! camera-type eye morphogenesis GO:0048593 25 22 1,000 1,392E-04 4,971E-03 ! response to corticosteroid stimulus GO:0031960 24 23 1,000 1,524E-04 5,388E-03 ! regulation of behavior GO:0050795 23 23 1,000 1,524E-04 5,335E-03 ! cell surface binding GO:0043498 25 23 1,000 1,524E-04 5,283E-03 ! collagen binding GO:0005518 27 23 1,000 1,524E-04 5,233E-03 ! regulation of coagulation GO:0050818 25 23 1,000 1,524E-04 5,183E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 24 24 1,000 1,662E-04 5,598E-03 ! calcium-dependent phospholipid binding GO:0005544 24 24 1,000 1,662E-04 5,546E-03 ! regulation of fibroblast proliferation GO:0048145 25 24 1,000 1,662E-04 5,494E-03 ! negative regulation of protein modification process GO:0031400 28 24 1,000 1,662E-04 5,444E-03 ! RNA export from nucleus GO:0006405 27 25 1,000 1,805E-04 5,861E-03 ! actin filament GO:0005884 28 25 1,000 1,805E-04 5,808E-03 ! blastocyst development GO:0001824 25 25 1,000 1,805E-04 5,756E-03 ! heterochromatin GO:0000792 26 25 1,000 1,805E-04 5,705E-03 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 26 26 1,000 1,955E-04 6,124E-03 ! lysine N-acetyltransferase activity GO:0004468 26 26 1,000 1,955E-04 6,07E-03 GO:0004402|histone acetyltransferase activity, ! regulation of endothelial cell proliferation GO:0001936 27 26 1,000 1,955E-04 6,018E-03 ! fat cell differentiation GO:0045444 26 26 1,000 1,955E-04 5,967E-03 ! histone deacetylase complex GO:0000118 27 26 1,000 1,955E-04 5,916E-03 ! response to endoplasmic reticulum stress GO:0034976 29 26 1,000 1,955E-04 5,866E-03 ! collagen metabolic process GO:0032963 27 27 1,000 2,11E-04 6,28E-03 ! deoxyribonuclease activity GO:0004536 28 28 1,000 2,272E-04 6,704E-03 ! ER-nuclear signaling pathway GO:0006984 31 28 1,000 2,272E-04 6,649E-03 ! response to mechanical stimulus GO:0009612 28 28 1,000 2,272E-04 6,595E-03 ! protein kinase inhibitor activity GO:0004860 28 28 1,000 2,272E-04 6,542E-03 ! serine family amino acid metabolic process GO:0009069 30 29 1,000 2,439E-04 6,967E-03 ! erythrocyte differentiation GO:0030218 32 30 1,000 2,612E-04 7,402E-03 ! kinase inhibitor activity GO:0019210 30 30 1,000 2,612E-04 7,344E-03 ! negative regulation of hydrolase activity GO:0051346 32 30 1,000 2,612E-04 7,287E-03 ! negative regulation of cell activation GO:0050866 31 30 1,000 2,612E-04 7,23E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 30 30 1,000 2,612E-04 7,175E-03 ! placenta development GO:0001890 31 31 1,000 2,791E-04 7,607E-03 ! response to hydrogen peroxide GO:0042542 34 32 1,000 2,975E-04 8,049E-03 ! endoribonuclease activity GO:0004521 34 33 1,000 3,166E-04 8,5E-03 ! eye morphogenesis GO:0048592 38 33 1,000 3,166E-04 8,437E-03 ! embryonic organ development GO:0048568 36 33 1,000 3,166E-04 8,374E-03 ! collagen GO:0005581 35 34 1,000 3,362E-04 8,828E-03 ! positive regulation of DNA metabolic process GO:0051054 40 35 1,000 3,564E-04 9,291E-03 ! vesicle lumen GO:0031983 37 35 1,000 3,564E-04 9,224E-03 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! response to calcium ion GO:0051592 39 35 1,000 3,564E-04 9,157E-03 ! erythrocyte homeostasis GO:0034101 37 35 1,000 3,564E-04 9,092E-03 ! multicellular organismal metabolic process GO:0044236 38 37 1,000 3,986E-04 0,01009549 ! odontogenesis GO:0042476 40 38 1,000 4,206E-04 0,01057652 ! cell growth GO:0016049 40 38 1,000 4,206E-04 0,01050256 ! positive regulation of cell cycle GO:0045787 39 39 1,000 4,431E-04 0,01098842 ! positive regulation of response to external stimulus GO:0032103 39 39 1,000 4,431E-04 0,01091263 ! nuclear export GO:0051168 42 40 1,000 4,662E-04 0,01140314 ! response to insulin stimulus GO:0032868 45 40 1,000 4,662E-04 0,01132557 ! response to reactive oxygen species GO:0000302 43 41 1,000 4,899E-04 0,01182057 ! exonuclease activity GO:0004527 42 41 1,000 4,899E-04 0,01174124 ! double-strand break repair GO:0006302 41 41 1,000 4,899E-04 0,01166296 ! damaged DNA binding GO:0003684 42 42 1,000 5,142E-04 0,01215951 ! negative regulation of cell migration GO:0030336 44 42 1,000 5,142E-04 0,01207951 ! positive regulation of growth GO:0045927 42 42 1,000 5,142E-04 0,01200056 ! induction of apoptosis by intracellular signals GO:0008629 46 43 1,000 5,39E-04 0,01249857 ! keratinocyte differentiation GO:0030216 46 43 1,000 5,39E-04 0,01241793 ! histone modification GO:0016570 44 43 1,000 5,39E-04 0,01233833 ! G1/S transition of mitotic cell cycle GO:0000082 47 46 1,000 6,17E-04 0,0140328 ! covalent chromatin modification GO:0016569 47 46 1,000 6,17E-04 0,01394399 ! epidermal cell differentiation GO:0009913 51 48 1,000 6,718E-04 0,01508769 ! protein N-terminus binding GO:0047485 51 48 1,000 6,718E-04 0,01499339 ! transferase activity, transferring sulfur-containing groups GO:0016782 50 49 1,000 7,001E-04 0,01552729 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 54 49 1,000 7,001E-04 0,01543144 ! ribonuclease activity GO:0004540 50 49 1,000 7,001E-04 0,01533677 ! lamellipodium GO:0030027 53 49 1,000 7,001E-04 0,01524325 ! negative regulation of cell motion GO:0051271 51 49 1,000 7,001E-04 0,01515087 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 1,000 7,289E-04 0,01567998 ! nuclear periphery GO:0034399 53 50 1,000 7,289E-04 0,01558609 ! positive regulation of cell migration GO:0030335 55 52 1,000 7,883E-04 0,01675555 ! DNA damage response, signal transduction GO:0042770 58 52 1,000 7,883E-04 0,01665641 ! positive regulation of protein amino acid phosphorylation GO:0001934 54 52 1,000 7,883E-04 0,01655843 ! N-acetyltransferase activity GO:0008080 54 53 1,000 8,188E-04 0,01709941 ! pyridoxal phosphate binding GO:0030170 56 53 1,000 8,188E-04 0,017 GO:0070279|vitamin B6 binding, ! cell projection assembly GO:0030031 56 53 1,000 8,188E-04 0,01690173 ! growth factor receptor binding GO:0070851 56 54 1,000 8,499E-04 0,01744303 ! nucleotide-excision repair GO:0006289 58 55 1,000 8,816E-04 0,01798968 ! camera-type eye development GO:0043010 59 56 1,000 9,138E-04 0,01854157 ! positive regulation of phosphorylation GO:0042327 59 57 1,000 9,466E-04 0,0190986 ! positive regulation of phosphorus metabolic process GO:0010562 61 58 1,000 9,8E-04 0,01966067 GO:0045937|positive regulation of phosphate metabolic process, ! extracellular matrix organization GO:0030198 59 58 1,000 9,8E-04 0,01955084 ! positive regulation of cell motion GO:0051272 61 58 1,000 9,8E-04 0,01944222 ! homeostasis of number of cells GO:0048872 62 58 1,000 9,8E-04 0,0193348 ! chromatin remodeling complex GO:0016585 61 59 1,000 1,014E-03 0,01989425 ! multicellular organism reproduction GO:0032504 62 60 1,000 1,048E-03 0,02045854 GO:0048609|reproductive process in a multicellular organism, ! regulation of lipid metabolic process GO:0019216 63 60 1,000 1,048E-03 0,02034735 ! myeloid cell differentiation GO:0030099 64 60 1,000 1,048E-03 0,02023737 ! negative regulation of protein kinase activity GO:0006469 67 61 1,000 1,083E-03 0,02080147 ! negative regulation of kinase activity GO:0033673 68 62 1,000 1,119E-03 0,02137024 ! transforming growth factor beta receptor signaling pathway GO:0007179 67 64 1,000 1,192E-03 0,02264118 ! lung development GO:0030324 65 64 1,000 1,192E-03 0,02252139 ! negative regulation of transferase activity GO:0051348 71 65 1,000 1,229E-03 0,0231036 ! response to metal ion GO:0010038 69 65 1,000 1,229E-03 0,02298264 ! positive regulation of protein modification process GO:0031401 69 65 1,000 1,229E-03 0,02286294 ! response to steroid hormone stimulus GO:0048545 69 66 1,000 1,267E-03 0,02344463 ! response to unfolded protein GO:0006986 68 66 1,000 1,267E-03 0,02332378 ! response to nutrient GO:0007584 67 66 1,000 1,267E-03 0,02320418 ! acetyltransferase activity GO:0016407 68 66 1,000 1,267E-03 0,02308579 ! respiratory tube development GO:0030323 68 67 1,000 1,305E-03 0,02366462 ! regulation of caspase activity GO:0043281 70 67 1,000 1,305E-03 0,0235451 ! regulation of actin cytoskeleton organization GO:0032956 74 68 1,000 1,344E-03 0,02412577 ! respiratory system development GO:0060541 69 68 1,000 1,344E-03 0,02400514 ! N-acyltransferase activity GO:0016410 69 68 1,000 1,344E-03 0,02388571 ! regulation of endopeptidase activity GO:0052548 72 69 1,000 1,384E-03 0,02446587 ! eye development GO:0001654 74 69 1,000 1,384E-03 0,02434534 ! response to hypoxia GO:0001666 76 70 1,000 1,424E-03 0,02492725 ! female pregnancy GO:0007565 71 70 1,000 1,424E-03 0,02480566 ! cell cortex GO:0005938 74 70 1,000 1,424E-03 0,02468524 ! response to oxygen levels GO:0070482 77 71 1,000 1,465E-03 0,02526661 ! regulation of actin filament-based process GO:0032970 77 71 1,000 1,465E-03 0,02514514 ! response to protein stimulus GO:0051789 74 72 1,000 1,506E-03 0,02572818 ! regulation of peptidase activity GO:0052547 78 74 1,000 1,59E-03 0,02703378 ! regulation of Rho protein signal transduction GO:0035023 79 74 1,000 1,59E-03 0,02690566 ! establishment of RNA localization GO:0051236 78 75 1,000 1,633E-03 0,02749996 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 80 76 1,000 1,676E-03 0,02809789 ! RNA localization GO:0006403 80 77 1,000 1,72E-03 0,02869938 ! endonuclease activity GO:0004519 80 77 1,000 1,72E-03 0,0285659 ! extracellular matrix structural constituent GO:0005201 80 77 1,000 1,72E-03 0,02843365 ! regulation of cell adhesion GO:0030155 82 78 1,000 1,764E-03 0,02903429 ! cofactor biosynthetic process GO:0051188 81 78 1,000 1,764E-03 0,0289011 ! positive regulation of MAP kinase activity GO:0043406 85 79 1,000 1,809E-03 0,02950303 ! regulation of Ras GTPase activity GO:0032318 84 80 1,000 1,855E-03 0,03010835 ! protein kinase binding GO:0019901 89 80 1,000 1,855E-03 0,02997212 ! interphase of mitotic cell cycle GO:0051329 84 82 1,000 1,948E-03 0,03132893 GO:0051325|interphase, ! extracellular matrix part GO:0044420 85 83 1,000 1,995E-03 0,03194407 ! mitochondrion organization GO:0007005 86 83 1,000 1,995E-03 0,03180146 ! cell leading edge GO:0031252 90 83 1,000 1,995E-03 0,03166012 ! sulfur metabolic process GO:0006790 90 89 1,000 2,289E-03 0,03617334 ! negative regulation of multicellular organismal process GO:0051241 93 89 1,000 2,289E-03 0,03601398 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 92 89 1,000 2,289E-03 0,03585603 ! nuclear membrane GO:0031965 92 90 1,000 2,34E-03 0,03649429 ! growth factor binding GO:0019838 92 90 1,000 2,34E-03 0,03633562 ! in utero embryonic development GO:0001701 97 95 1,000 2,603E-03 0,04024251 ! regulation of response to external stimulus GO:0032101 97 95 1,000 2,603E-03 0,04006905 ! response to nutrient levels GO:0031667 98 96 1,000 2,657E-03 0,04072752 ! regulation of GTPase activity GO:0043087 104 97 1,000 2,712E-03 0,0413885 ! chromatin binding GO:0003682 102 99 1,000 2,823E-03 0,04289959 ! protein C-terminus binding GO:0008022 106 99 1,000 2,823E-03 0,04271781 ! regulation of cellular component biogenesis GO:0044087 106 99 1,000 2,823E-03 0,04253756 ! kinase binding GO:0019900 108 99 1,000 2,823E-03 0,04235884 ! electron transport chain GO:0022900 102 100 1,000 2,879E-03 0,04302298 ! chromatin assembly or disassembly GO:0006333 104 100 1,000 2,879E-03 0,04284372 ! tRNA transcription GO:0009304 5 5 0,000 4,066E-03 0,06024969 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 5 5 0,000 4,066E-03 0,06000073 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 4,066E-03 0,05975381 ! benzene and derivative metabolic process GO:0042537 5 5 0,000 4,066E-03 0,05950892 ! response to oxygen radical GO:0000305 5 5 0,000 4,066E-03 0,05926602 ! positive regulation of axon extension GO:0045773 6 5 0,000 4,066E-03 0,05902511 ! negative regulation of bone resorption GO:0045779 5 5 0,000 4,066E-03 0,05878614 ! positive regulation of lipid biosynthetic process GO:0046889 5 5 0,000 4,066E-03 0,0585491 ! regulation of interferon-beta production GO:0032648 6 5 0,000 4,066E-03 0,05831396 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! sodium-independent organic anion transmembrane transporter activity GO:0015347 6 5 0,000 4,066E-03 0,0580807 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 4,066E-03 0,05784931 ! negative regulation of transmembrane transport GO:0034763 5 5 0,000 4,066E-03 0,05761975 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! hypothalamus development GO:0021854 5 5 0,000 4,066E-03 0,057392 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 4,066E-03 0,05716605 ! N-terminal protein lipidation GO:0006498 5 5 0,000 4,066E-03 0,05694187 ! glycolipid transport GO:0046836 5 5 0,000 4,066E-03 0,05671944 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 5 5 0,000 4,066E-03 0,05649874 ! phosphoinositide 3-kinase binding GO:0043548 5 5 0,000 4,066E-03 0,05627975 ! protein amino acid sulfation GO:0006477 5 5 0,000 4,066E-03 0,05606246 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 6 5 0,000 4,066E-03 0,05584683 ! opioid peptide activity GO:0001515 5 5 0,000 4,066E-03 0,05563286 ! selenocysteine incorporation GO:0001514 5 5 0,000 4,066E-03 0,05542052 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 5 5 0,000 4,066E-03 0,05520979 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 5 5 0,000 4,066E-03 0,05500067 ! elastic fiber assembly GO:0048251 5 5 0,000 4,066E-03 0,05479312 ! regulation of mitochondrial membrane permeability GO:0046902 5 5 0,000 4,066E-03 0,05458713 ! neurofilament cytoskeleton organization GO:0060052 5 5 0,000 4,066E-03 0,05438268 ! ruffle membrane GO:0032587 5 5 0,000 4,066E-03 0,05417976 ! regulation of histone modification GO:0031056 5 5 0,000 4,066E-03 0,05397835 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 4,066E-03 0,05377843 ! behavioral response to pain GO:0048266 5 5 0,000 4,066E-03 0,05357999 ! clathrin coat assembly GO:0048268 6 5 0,000 4,066E-03 0,053383 ! Notch receptor processing GO:0007220 5 5 0,000 4,066E-03 0,05318746 ! cerebral cortex radially oriented cell migration GO:0021799 5 5 0,000 4,066E-03 0,05299334 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 6 5 0,000 4,066E-03 0,05280064 ! serotonin receptor signaling pathway GO:0007210 5 5 0,000 4,066E-03 0,05260933 ! oxidoreductase activity, oxidizing metal ions GO:0016722 5 5 0,000 4,066E-03 0,05241941 ! response to lipid GO:0033993 5 5 0,000 4,066E-03 0,05223085 ! cytoplasmic dynein complex GO:0005868 6 5 0,000 4,066E-03 0,05204364 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 4,066E-03 0,05185777 ! positive regulation of muscle cell differentiation GO:0051149 5 5 0,000 4,066E-03 0,05167322 ! smooth muscle cell differentiation GO:0051145 5 5 0,000 4,066E-03 0,05148999 ! exo-alpha-sialidase activity GO:0004308 5 5 0,000 4,066E-03 0,05130804 GO:0016997|alpha-sialidase activity, ! regulation of odontogenesis GO:0042481 5 5 0,000 4,066E-03 0,05112738 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 4,066E-03 0,05094799 ! formate-tetrahydrofolate ligase activity GO:0004329 5 5 0,000 4,066E-03 0,05076985 ! negative regulation of heart contraction GO:0045822 5 5 0,000 4,066E-03 0,05059295 ! ovulation from ovarian follicle GO:0001542 5 5 0,000 4,066E-03 0,05041728 ! DNA ligation during DNA repair GO:0051103 5 5 0,000 4,066E-03 0,05024282 ! 1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 5 5 0,000 4,066E-03 0,05006957 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 4,066E-03 0,04989751 ! negative regulation of endocytosis GO:0045806 5 5 0,000 4,066E-03 0,04972663 ! microfibril GO:0001527 5 5 0,000 4,066E-03 0,04955691 GO:0043205|fibril, ! parathyroid gland development GO:0060017 5 5 0,000 4,066E-03 0,04938835 ! toxin metabolic process GO:0009404 5 5 0,000 4,066E-03 0,04922094 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 4,066E-03 0,04905465 ! cytokine secretion GO:0050663 5 5 0,000 4,066E-03 0,04888948 ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 5 5 0,000 4,066E-03 0,04872542 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 4,066E-03 0,04856246 ! skeletal myofibril assembly GO:0014866 5 5 0,000 4,066E-03 0,04840059 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 5 0,000 4,066E-03 0,04823979 ! epithelial cell proliferation GO:0050673 5 5 0,000 4,066E-03 0,04808005 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 5 5 0,000 4,066E-03 0,04792137 ! regulation of retroviral genome replication GO:0045091 5 5 0,000 4,066E-03 0,04776374 ! negative regulation of survival gene product expression GO:0008634 5 5 0,000 4,066E-03 0,04760713 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 4,066E-03 0,04745156 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of defense response to virus by host GO:0050691 5 5 0,000 4,066E-03 0,04729699 ! transmembrane-ephrin receptor activity GO:0005005 5 5 0,000 4,066E-03 0,04714343 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 4,066E-03 0,04699086 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 4,066E-03 0,04683928 ! glutamate catabolic process GO:0006538 6 5 0,000 4,066E-03 0,04668867 ! positive regulation of isotype switching to IgG isotypes GO:0048304 9 5 0,000 4,066E-03 0,04653903 ! microvillus organization GO:0032528 5 5 0,000 4,066E-03 0,04639034 GO:0030033|microvillus assembly, ! tyrosine catabolic process GO:0006572 5 5 0,000 4,066E-03 0,0462426 ! L-serine biosynthetic process GO:0006564 5 5 0,000 4,066E-03 0,0460958 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 4,066E-03 0,04594992 ! pericentriolar material GO:0000242 6 5 0,000 4,066E-03 0,04580497 ! polyol biosynthetic process GO:0046173 5 5 0,000 4,066E-03 0,04566093 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 6 5 0,000 4,066E-03 0,04551779 ! platelet-derived growth factor alpha-receptor activity GO:0005018 5 5 0,000 4,066E-03 0,04537555 ! proton-transporting V-type ATPase, V0 domain GO:0033179 5 5 0,000 4,066E-03 0,04523419 ! fibroblast growth factor receptor activity GO:0005007 5 5 0,000 4,066E-03 0,04509371 ! protein-DNA loading ATPase activity GO:0033170 5 5 0,000 4,066E-03 0,04495411 GO:0003689|DNA clamp loader activity, ! insulin-like growth factor receptor activity GO:0005010 5 5 0,000 4,066E-03 0,04481536 ! response to tumor necrosis factor GO:0034612 6 5 0,000 4,066E-03 0,04467746 ! mRNA transcription GO:0009299 6 5 0,000 4,066E-03 0,04454042 ! response to ATP GO:0033198 5 5 0,000 4,066E-03 0,04440421 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 5 5 0,000 4,066E-03 0,04426883 ! adenosine receptor activity, G-protein coupled GO:0001609 5 5 0,000 4,066E-03 0,04413427 ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 4,066E-03 0,04400053 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 5 5 0,000 4,066E-03 0,0438676 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 4,066E-03 0,04373547 ! multivesicular body GO:0005771 5 5 0,000 4,066E-03 0,04360413 ! positive regulation of transporter activity GO:0032411 5 5 0,000 4,066E-03 0,04347358 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 5 5 0,000 4,066E-03 0,04334381 ! forebrain neuron development GO:0021884 6 5 0,000 4,066E-03 0,04321481 ! insulin-like growth factor I binding GO:0031994 5 5 0,000 4,066E-03 0,04308658 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 5 5 0,000 4,066E-03 0,0429591 ! demethylase activity GO:0032451 5 5 0,000 4,066E-03 0,04283238 ! peptidyl-histidine phosphorylation GO:0018106 5 5 0,000 4,066E-03 0,0427064 ! epithelial cell maturation GO:0002070 5 5 0,000 4,066E-03 0,04258116 ! nitric-oxide synthase regulator activity GO:0030235 5 5 0,000 4,066E-03 0,04245666 ! regulation of immunoglobulin secretion GO:0051023 5 5 0,000 4,066E-03 0,04233287 ! zymogen granule GO:0042588 5 5 0,000 4,066E-03 0,04220981 ! guanylate cyclase regulator activity GO:0030249 5 5 0,000 4,066E-03 0,04208747 GO:0010851|cyclase regulator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 4,066E-03 0,04196583 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,066E-03 0,04184489 ! early endosome to late endosome transport GO:0045022 5 5 0,000 4,066E-03 0,04172464 ! positive regulation of translational initiation GO:0045948 5 5 0,000 4,066E-03 0,04160509 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 4,066E-03 0,04148622 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 4,066E-03 0,04136802 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! semaphorin receptor activity GO:0017154 6 5 0,000 4,066E-03 0,0412505 ! proteoglycan binding GO:0043394 9 5 0,000 4,066E-03 0,04113364 ! regulation of collagen metabolic process GO:0010712 6 5 0,000 4,066E-03 0,04101745 ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 6 5 0,000 4,066E-03 0,0409019 ! zinc ion homeostasis GO:0055069 5 5 0,000 4,066E-03 0,04078701 GO:0006882|cellular zinc ion homeostasis, ! deoxyribonucleoside metabolic process GO:0009120 6 5 0,000 4,066E-03 0,04067276 ! nucleoside monophosphate catabolic process GO:0009125 5 5 0,000 4,066E-03 0,04055915 ! activated T cell proliferation GO:0050798 6 5 0,000 4,066E-03 0,04044617 ! advanced glycation end-product receptor activity GO:0050785 5 5 0,000 4,066E-03 0,04033382 ! dynein binding GO:0045502 5 5 0,000 4,066E-03 0,04022209 ! regulation of dendrite development GO:0050773 5 5 0,000 4,066E-03 0,04011098 ! cardiac muscle cell development GO:0055013 5 5 0,000 4,066E-03 0,04000049 ! anterograde axon cargo transport GO:0008089 5 5 0,000 4,066E-03 0,03989059 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,066E-03 0,0397813 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 4,066E-03 0,03967261 GO:0003923|GPI-anchor transamidase activity, ! lymphoid progenitor cell differentiation GO:0002320 5 5 0,000 4,066E-03 0,03956451 ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 4,066E-03 0,039457 ! sphingomyelin catabolic process GO:0006685 6 5 0,000 4,066E-03 0,03935007 ! high-density lipoprotein binding GO:0008035 5 5 0,000 4,066E-03 0,03924372 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 4,066E-03 0,03913794 ! positive regulation of B cell differentiation GO:0045579 5 5 0,000 4,066E-03 0,03903273 ! regulation of acetylcholine secretion GO:0014056 5 5 0,000 4,066E-03 0,03892809 ! centromeric DNA binding GO:0019237 5 5 0,000 4,066E-03 0,038824 ! cyclohydrolase activity GO:0019238 5 5 0,000 4,066E-03 0,03872047 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 4,066E-03 0,03861749 ! positive T cell selection GO:0043368 9 5 0,000 4,066E-03 0,03851506 ! neural tube patterning GO:0021532 5 5 0,000 4,066E-03 0,03841316 ! amylase activity GO:0016160 5 5 0,000 4,066E-03 0,03831181 ! metaphase plate congression GO:0051310 5 5 0,000 4,066E-03 0,03821099 ! regulation of sterol transport GO:0032371 5 5 0,000 4,066E-03 0,0381107 GO:0032374|regulation of cholesterol transport, ! sympathetic nervous system development GO:0048485 5 5 0,000 4,066E-03 0,03801093 ! oxygen homeostasis GO:0032364 5 5 0,000 4,066E-03 0,03791169 ! skeletal muscle regeneration GO:0043403 5 5 0,000 4,066E-03 0,03781296 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 5 5 0,000 4,066E-03 0,03771474 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 5 5 0,000 4,066E-03 0,03761704 ! SAP kinase activity GO:0016909 5 5 0,000 4,066E-03 0,03751983 ! positive regulation of pseudopodium assembly GO:0031274 5 5 0,000 4,066E-03 0,03742313 GO:0031272|regulation of pseudopodium assembly, ! alpha-mannosidase activity GO:0004559 6 5 0,000 4,066E-03 0,03732693 ! alpha-glucosidase activity GO:0004558 6 5 0,000 4,066E-03 0,03723122 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 4,066E-03 0,037136 ! myeloid dendritic cell activation GO:0001773 5 5 0,000 4,066E-03 0,03704127 GO:0043011|myeloid dendritic cell differentiation, ! anaphase GO:0051322 5 5 0,000 4,066E-03 0,03694701 GO:0000090|mitotic anaphase, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 4,066E-03 0,03685324 ! CARD domain binding GO:0050700 5 5 0,000 4,066E-03 0,03675994 ! regulation of muscle cell apoptosis GO:0010660 5 5 0,000 4,066E-03 0,03666711 ! AP-2 adaptor complex GO:0030122 5 5 0,000 4,066E-03 0,03657475 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 5 5 0,000 4,066E-03 0,03648285 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 4,066E-03 0,03639142 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 4,066E-03 0,03630044 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 4,066E-03 0,03620992 ! negative regulation of macrophage differentiation GO:0045650 5 5 0,000 4,066E-03 0,03611984 ! negative regulation of osteoclast differentiation GO:0045671 5 5 0,000 4,066E-03 0,03603021 ! ceramidase activity GO:0017040 5 5 0,000 4,066E-03 0,03594103 ! negative regulation of osteoblast differentiation GO:0045668 6 5 0,000 4,066E-03 0,03585229 ! GTP-Rho binding GO:0017049 5 5 0,000 4,066E-03 0,03576398 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 4,066E-03 0,03567611 ! chondroitin sulfotransferase activity GO:0034481 5 5 0,000 4,066E-03 0,03558867 ! positive regulation of T-helper 2 cell differentiation GO:0045630 5 5 0,000 4,066E-03 0,03550165 ! alcohol transmembrane transporter activity GO:0015665 5 5 0,000 4,066E-03 0,03541506 GO:0015166|polyol transmembrane transporter activity, ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 4,066E-03 0,0353289 ! TAP complex GO:0042825 5 5 0,000 4,066E-03 0,03524315 ! bHLH transcription factor binding GO:0043425 5 5 0,000 4,066E-03 0,03515781 ! actinin binding GO:0042805 6 5 0,000 4,066E-03 0,03507289 ! secretory granule organization GO:0033363 5 5 0,000 4,066E-03 0,03498838 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 4,066E-03 0,03490427 ! striatum development GO:0021756 5 5 0,000 4,066E-03 0,03482057 ! photoreceptor inner segment GO:0001917 5 5 0,000 4,066E-03 0,03473726 ! regulation of T cell mediated cytotoxicity GO:0001914 9 5 0,000 4,066E-03 0,03465436 ! aldehyde-lyase activity GO:0016832 5 5 0,000 4,066E-03 0,03457185 ! regulation of mitochondrial depolarization GO:0051900 5 5 0,000 4,066E-03 0,03448973 ! T cell activation during immune response GO:0002286 5 5 0,000 4,066E-03 0,034408 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 4,066E-03 0,03432666 ! 1-aminocyclopropane-1-carboxylate synthase activity GO:0016847 5 5 0,000 4,066E-03 0,0342457 ! dystroglycan complex GO:0016011 6 5 0,000 4,066E-03 0,03416512 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 5 5 0,000 4,066E-03 0,03408492 ! neural plate development GO:0001840 5 5 0,000 4,066E-03 0,0340051 ! toll-like receptor signaling pathway GO:0002224 5 5 0,000 4,066E-03 0,03392565 ! phosphopantetheine binding GO:0031177 5 5 0,000 4,066E-03 0,03384656 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 4,066E-03 0,03376785 ! negative regulation of actin filament bundle formation GO:0032232 8 5 0,000 4,066E-03 0,0336895 GO:0051497|negative regulation of stress fiber formation, ! organ or tissue specific immune response GO:0002251 5 5 0,000 4,066E-03 0,03361152 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 4,066E-03 0,03353389 ! diacylglycerol metabolic process GO:0046339 5 5 0,000 4,066E-03 0,03345663 ! cytoplasmic microtubule organization GO:0031122 5 5 0,000 4,066E-03 0,03337972 ! retina homeostasis GO:0001895 5 5 0,000 4,066E-03 0,03330316 ! release of sequestered calcium ion into cytosol GO:0051209 10 5 0,000 4,066E-03 0,03322695 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 5 5 0,000 4,066E-03 0,03315109 ! regulation of growth hormone secretion GO:0060123 6 5 0,000 4,066E-03 0,03307557 ! collagen type IV GO:0005587 5 5 0,000 4,066E-03 0,0330004 ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 4,066E-03 0,03292557 ! testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045 5 5 0,000 4,066E-03 0,03285108 ! retrograde protein transport, ER to cytosol GO:0030970 5 5 0,000 4,066E-03 0,03277692 ! spindle assembly GO:0051225 5 5 0,000 4,066E-03 0,0327031 ! ensheathment of axons in the peripheral nervous system GO:0032292 5 5 0,000 4,066E-03 0,03262961 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 5 5 0,000 4,066E-03 0,03255645 ! protein amino acid prenylation GO:0018346 5 5 0,000 4,066E-03 0,03248362 ! stem cell division GO:0017145 5 5 0,000 4,066E-03 0,03241111 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 4,066E-03 0,03233892 ! phospholipid scrambling GO:0017121 5 5 0,000 4,066E-03 0,03226706 GO:0017128|phospholipid scramblase activity, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 5 0,000 4,066E-03 0,03219551 ! regulation of humoral immune response GO:0002920 9 5 0,000 4,066E-03 0,03212428 ! H3/H4 histone acetyltransferase activity GO:0004406 5 5 0,000 4,066E-03 0,03205337 ! regulation of interferon-alpha biosynthetic process GO:0045354 6 5 0,000 4,066E-03 0,03198277 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 4,066E-03 0,03191247 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 5 5 0,000 4,066E-03 0,03184249 GO:0030816|positive regulation of cAMP metabolic process, ! phagocytic vesicle GO:0045335 5 5 0,000 4,066E-03 0,03177281 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 4,066E-03 0,03170344 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 4,066E-03 0,03163437 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 4,066E-03 0,0315656 ! polyol transport GO:0015791 6 5 0,000 4,066E-03 0,03149713 ! cell adhesion mediated by integrin GO:0033627 6 5 0,000 4,066E-03 0,03142895 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 4,066E-03 0,03136107 ! glycerol-3-phosphate metabolic process GO:0006072 5 5 0,000 4,066E-03 0,03129348 ! platelet activating factor metabolic process GO:0046469 5 5 0,000 4,066E-03 0,03122619 ! cobalt ion transport GO:0006824 5 5 0,000 4,066E-03 0,03115918 ! response to zinc ion GO:0010043 5 5 0,000 4,066E-03 0,03109245 ! poly(U) RNA binding GO:0008266 5 5 0,000 4,066E-03 0,03102602 ! negative regulation of cell-cell adhesion GO:0022408 5 5 0,000 4,066E-03 0,03095986 ! adaptation of signaling pathway GO:0022401 5 5 0,000 4,066E-03 0,03089399 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! glucocorticoid receptor signaling pathway GO:0042921 5 5 0,000 4,066E-03 0,0308284 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 5 5 0,000 4,066E-03 0,03076308 ! sensory perception of bitter taste GO:0050913 5 5 0,000 4,066E-03 0,03069805 ! regulation of dopamine uptake GO:0051584 5 5 0,000 4,066E-03 0,03063328 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! opsonization GO:0008228 5 5 0,000 4,066E-03 0,03056879 ! protein maturation by protein folding GO:0022417 5 5 0,000 4,066E-03 0,03050457 ! neuron remodeling GO:0016322 6 5 0,000 4,066E-03 0,03044062 ! neurexin binding GO:0042043 5 5 0,000 4,066E-03 0,03037694 ! sensory perception of temperature stimulus GO:0050951 5 5 0,000 4,066E-03 0,03031352 ! regulation of potassium ion transport GO:0043266 5 5 0,000 4,066E-03 0,03025037 ! low-density lipoprotein particle GO:0034362 5 5 0,000 4,066E-03 0,03018748 ! chemoattractant activity GO:0042056 5 5 0,000 4,066E-03 0,03012485 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 6 5 0,000 4,066E-03 0,03006248 ! lipoic acid binding GO:0031405 5 5 0,000 4,066E-03 0,03000036 ! lithium ion binding GO:0031403 6 5 0,000 4,066E-03 0,02993851 ! lipoprotein particle clearance GO:0034381 5 5 0,000 4,066E-03 0,02987691 ! grooming behavior GO:0007625 5 5 0,000 4,066E-03 0,02981556 ! sequestering of actin monomers GO:0042989 5 5 0,000 4,066E-03 0,02975446 ! cobalamin binding GO:0031419 5 5 0,000 4,066E-03 0,02969361 ! retinoic acid binding GO:0001972 5 5 0,000 4,066E-03 0,02963301 ! response to axon injury GO:0048678 5 5 0,000 4,066E-03 0,02957266 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 4,066E-03 0,02951255 ! regulation of activin receptor signaling pathway GO:0032925 5 5 0,000 4,066E-03 0,02945269 ! positive regulation of neurotransmitter secretion GO:0001956 5 5 0,000 4,066E-03 0,02939307 ! mitochondrial genome maintenance GO:0000002 5 5 0,000 4,066E-03 0,02933369 ! protein-lysine 6-oxidase activity GO:0004720 6 5 0,000 4,066E-03 0,02927455 ! female pronucleus GO:0001939 5 5 0,000 4,066E-03 0,02921565 ! F-actin capping protein complex GO:0008290 5 5 0,000 4,066E-03 0,02915698 ! DNA topoisomerase activity GO:0003916 5 5 0,000 4,066E-03 0,02909855 ! poly(ADP-ribose) glycohydrolase activity GO:0004649 6 5 0,000 4,066E-03 0,02904035 ! spinal cord dorsal/ventral patterning GO:0021513 5 5 0,000 4,066E-03 0,02898239 ! dorsal spinal cord development GO:0021516 5 5 0,000 4,066E-03 0,02892465 ! ceramide catabolic process GO:0046514 5 5 0,000 4,066E-03 0,02886715 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 4,066E-03 0,02880987 ! neutrophil mediated immunity GO:0002446 5 5 0,000 4,066E-03 0,02875282 ! regulation of oligodendrocyte differentiation GO:0048713 5 5 0,000 4,066E-03 0,028696 ! Rap GTPase activator activity GO:0046582 5 5 0,000 4,066E-03 0,0286394 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 6 5 0,000 4,066E-03 0,02858302 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 5 5 0,000 4,066E-03 0,02852687 ! positive regulation of filopodium assembly GO:0051491 5 5 0,000 4,066E-03 0,02847093 GO:0051489|regulation of filopodium assembly, ! heart trabecula formation GO:0060347 5 5 0,000 4,066E-03 0,02841522 GO:0060343|trabecula formation, ! amine oxidase activity GO:0008131 6 5 0,000 4,066E-03 0,02835972 ! neutrophil activation GO:0042119 5 5 0,000 4,066E-03 0,02830444 ! regulation of response to food GO:0032095 5 5 0,000 4,066E-03 0,02824937 ! response to food GO:0032094 5 5 0,000 4,066E-03 0,02819452 ! hedgehog receptor activity GO:0008158 5 5 0,000 4,066E-03 0,02813988 ! protein phosphatase 1 binding GO:0008157 5 5 0,000 4,066E-03 0,02808545 ! lipoprotein catabolic process GO:0042159 5 5 0,000 4,066E-03 0,02803123 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 4,066E-03 0,02797722 ! organ growth GO:0035265 7 5 0,000 4,066E-03 0,02792342 ! positive regulation of multicellular organismal metabolic process GO:0044253 6 5 0,000 4,066E-03 0,02786982 ! small-subunit processome GO:0032040 5 5 0,000 4,066E-03 0,02781643 ! UDP-glucosyltransferase activity GO:0035251 5 5 0,000 4,066E-03 0,02776324 ! myosin heavy chain binding GO:0032036 5 5 0,000 4,066E-03 0,02771026 ! nucleoside salvage GO:0043174 7 5 0,000 4,066E-03 0,02765748 GO:0006166|purine ribonucleoside salvage, ! nucleobase transport GO:0015851 5 5 0,000 4,066E-03 0,0276049 ! GPI anchor binding GO:0034235 6 5 0,000 4,066E-03 0,02755252 ! thrombin receptor activity GO:0015057 5 5 0,000 4,066E-03 0,02750033 ! nucleotide-excision repair complex GO:0000109 6 5 0,000 4,066E-03 0,02744835 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 5 5 0,000 4,066E-03 0,02739656 ! dendritic shaft GO:0043198 5 5 0,000 4,066E-03 0,02734496 ! terminal button GO:0043195 8 5 0,000 4,066E-03 0,02729356 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 4,066E-03 0,02724236 GO:0016274|protein-arginine N-methyltransferase activity, ! ferrous iron binding GO:0008198 6 5 0,000 4,066E-03 0,02719134 ! eukaryotic initiation factor 4E binding GO:0008190 5 5 0,000 4,066E-03 0,02714052 ! G2/M transition checkpoint GO:0031576 5 5 0,000 4,066E-03 0,02708988 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of peptide secretion GO:0002792 6 5 0,000 4,066E-03 0,02703943 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 5 5 0,000 4,066E-03 0,02698917 ! response to UV-C GO:0010225 5 5 0,000 4,066E-03 0,0269391 ! carbonyl reductase (NADPH) activity GO:0004090 5 5 0,000 4,066E-03 0,02688921 ! regulation of alpha-beta T cell proliferation GO:0046640 9 5 0,000 4,066E-03 0,02683951 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! positive regulation of organ growth GO:0046622 5 5 0,000 4,066E-03 0,02678999 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 5 5 0,000 4,066E-03 0,02674066 ! IgE binding GO:0019863 5 5 0,000 4,066E-03 0,0266915 ! 3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 5 5 0,000 4,066E-03 0,02664252 ! monoamine transmembrane transporter activity GO:0008504 5 5 0,000 4,066E-03 0,02659373 ! response to cadmium ion GO:0046686 5 5 0,000 4,066E-03 0,02654511 ! regulation of interleukin-4 production GO:0032673 5 5 0,000 4,066E-03 0,02649667 ! hair follicle maturation GO:0048820 5 5 0,000 4,066E-03 0,02644841 ! regulation of interleukin-10 production GO:0032653 5 5 0,000 4,066E-03 0,02640032 ! ribosomal large subunit biogenesis GO:0042273 5 5 0,000 4,066E-03 0,02635241 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,066E-03 0,02630467 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 4,066E-03 0,0262571 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 4,066E-03 0,0262097 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 4,066E-03 0,02616248 GO:0005218|intracellular ligand-gated calcium channel activity, ! general transcriptional repressor activity GO:0016565 5 5 0,000 4,066E-03 0,02611542 ! peroxisome fission GO:0016559 5 5 0,000 4,066E-03 0,02606854 ! alpha-tubulin binding GO:0043014 5 5 0,000 4,066E-03 0,02602182 ! mitotic recombination GO:0006312 5 5 0,000 4,066E-03 0,02597527 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,066E-03 0,02592889 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 4,066E-03 0,02588267 ! positive regulation of chemokine production GO:0032722 5 5 0,000 4,066E-03 0,02583661 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 4,066E-03 0,02579072 ! muscle cell proliferation GO:0033002 5 5 0,000 4,066E-03 0,02574499 ! membrane to membrane docking GO:0022614 5 5 0,000 4,066E-03 0,02569943 ! translation activator activity GO:0008494 5 5 0,000 4,066E-03 0,02565402 ! N-formyl peptide receptor activity GO:0004982 5 5 0,000 4,066E-03 0,02560878 ! coenzyme A biosynthetic process GO:0015937 6 5 0,000 4,066E-03 0,02556369 ! histamine receptor activity GO:0004969 5 5 0,000 4,066E-03 0,02551876 ! dopamine receptor activity GO:0004952 5 5 0,000 4,066E-03 0,02547399 ! galactosidase activity GO:0015925 5 5 0,000 4,066E-03 0,02542938 ! prostaglandin E receptor activity GO:0004957 6 5 0,000 4,066E-03 0,02538492 ! cellular response to nutrient GO:0031670 5 5 0,000 4,066E-03 0,02534062 ! basic amino acid transmembrane transporter activity GO:0015174 5 5 0,000 4,066E-03 0,02529647 ! ATP-gated cation channel activity GO:0004931 7 5 0,000 4,066E-03 0,02525248 ! cytochrome-b5 reductase activity GO:0004128 5 5 0,000 4,066E-03 0,02520864 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 4,066E-03 0,02516495 ! glycine transmembrane transporter activity GO:0015187 5 5 0,000 4,066E-03 0,02512141 ! tyrosine phosphorylation of STAT protein GO:0007260 6 5 0,000 4,066E-03 0,02507802 ! tricarboxylic acid cycle enzyme complex GO:0045239 5 5 0,000 4,066E-03 0,02503479 ! RNA polymerase I transcription factor activity GO:0003701 5 5 0,000 4,066E-03 0,0249917 ! progesterone metabolic process GO:0042448 5 5 0,000 4,066E-03 0,02494876 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 5 5 0,000 4,066E-03 0,02490596 ! disaccharide metabolic process GO:0005984 5 5 0,000 4,066E-03 0,02486332 ! type II transforming growth factor beta receptor binding GO:0005114 5 5 0,000 4,066E-03 0,02482081 ! histone acetyltransferase binding GO:0035035 5 5 0,000 4,066E-03 0,02477846 ! endosome to lysosome transport GO:0008333 5 5 0,000 4,066E-03 0,02473625 ! glial cell migration GO:0008347 5 5 0,000 4,066E-03 0,02469418 ! S-acyltransferase activity GO:0016417 5 5 0,000 4,066E-03 0,02465225 ! phosphoinositide 3-kinase regulator activity GO:0035014 5 5 0,000 4,066E-03 0,02461047 ! phosphatidylinositol-4-phosphate 3-kinase activity GO:0035005 5 5 0,000 4,066E-03 0,02456883 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 4,066E-03 0,02452732 ! nucleobase transmembrane transporter activity GO:0015205 5 5 0,000 4,066E-03 0,02448596 ! asparaginase activity GO:0004067 5 5 0,000 4,066E-03 0,02444474 ! insemination GO:0007320 5 5 0,000 4,066E-03 0,02440366 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 4,066E-03 0,02436271 ! negative regulation of smooth muscle contraction GO:0045986 6 5 0,000 4,066E-03 0,0243219 ! aminoacylase activity GO:0004046 5 5 0,000 4,066E-03 0,02428123 ! receptor biosynthetic process GO:0032800 5 5 0,000 4,066E-03 0,02424069 ! penetration of zona pellucida GO:0007341 5 5 0,000 4,066E-03 0,02420029 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 6 5 0,000 4,066E-03 0,02416003 ! aldehyde reductase activity GO:0004032 5 5 0,000 4,066E-03 0,02411989 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 5 0,000 4,066E-03 0,02407989 ! unconventional myosin complex GO:0016461 5 5 0,000 4,066E-03 0,02404003 ! carnitine metabolic process GO:0009437 5 5 0,000 4,066E-03 0,02400029 GO:0006577|betaine metabolic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 6 6 0,000 4,878E-03 0,02874209 ! regulation of helicase activity GO:0051095 6 6 0,000 4,878E-03 0,02869474 ! testosterone 17-beta-dehydrogenase activity GO:0050327 6 6 0,000 4,878E-03 0,02864755 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 6 6 0,000 4,878E-03 0,02860051 ! tumor necrosis factor-mediated signaling pathway GO:0033209 6 6 0,000 4,878E-03 0,02855362 ! negative regulation of small GTPase mediated signal transduction GO:0051058 7 6 0,000 4,878E-03 0,02850689 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 7 6 0,000 4,878E-03 0,02846031 ! regulation of hormone biosynthetic process GO:0046885 6 6 0,000 4,878E-03 0,02841388 ! ephrin receptor binding GO:0046875 7 6 0,000 4,878E-03 0,0283676 ! biotin binding GO:0009374 7 6 0,000 4,878E-03 0,02832148 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 4,878E-03 0,0282755 ! insulin receptor substrate binding GO:0043560 7 6 0,000 4,878E-03 0,02822967 ! drug:hydrogen antiporter activity GO:0015307 6 6 0,000 4,878E-03 0,02818399 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 4,878E-03 0,02813846 ! carbohydrate phosphorylation GO:0046835 6 6 0,000 4,878E-03 0,02809308 ! regulation of respiratory gaseous exchange GO:0043576 6 6 0,000 4,878E-03 0,02804784 ! neuron adhesion GO:0007158 6 6 0,000 4,878E-03 0,02800275 ! establishment of tissue polarity GO:0007164 7 6 0,000 4,878E-03 0,0279578 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 6 6 0,000 4,878E-03 0,02791299 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 4,878E-03 0,02786833 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 6 0,000 4,878E-03 0,02782382 ! regulation of cardiac muscle cell proliferation GO:0060043 6 6 0,000 4,878E-03 0,02777944 ! positive regulation of receptor-mediated endocytosis GO:0048260 6 6 0,000 4,878E-03 0,0277352 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 6 6 0,000 4,878E-03 0,02769111 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 4,878E-03 0,02764716 ! eukaryotic translation elongation factor 1 complex GO:0005853 6 6 0,000 4,878E-03 0,02760334 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 4,878E-03 0,02755967 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 6 6 0,000 4,878E-03 0,02751613 ! cytoplasmic microtubule GO:0005881 7 6 0,000 4,878E-03 0,02747273 ! Arp2/3 protein complex GO:0005885 7 6 0,000 4,878E-03 0,02742946 ! neurofilament GO:0005883 6 6 0,000 4,878E-03 0,02738633 ! glial cell fate commitment GO:0021781 6 6 0,000 4,878E-03 0,02734334 ! dynactin complex GO:0005869 6 6 0,000 4,878E-03 0,02730048 ! fibroblast growth factor receptor antagonist activity GO:0030353 6 6 0,000 4,878E-03 0,02725776 GO:0005104|fibroblast growth factor receptor binding, GO:0005152|interleukin-1 receptor antagonist activity, ! translation repressor activity GO:0030371 6 6 0,000 4,878E-03 0,02721517 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 6 6 0,000 4,878E-03 0,02717271 ! lipopolysaccharide binding GO:0001530 6 6 0,000 4,878E-03 0,02713039 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 4,878E-03 0,02708819 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 4,878E-03 0,02704613 ! negative regulation of viral genome replication GO:0045071 6 6 0,000 4,878E-03 0,0270042 ! traversing start control point of mitotic cell cycle GO:0007089 6 6 0,000 4,878E-03 0,0269624 ! protein lipoylation GO:0009249 6 6 0,000 4,878E-03 0,02692072 ! regulation of isotype switching to IgG isotypes GO:0048302 10 6 0,000 4,878E-03 0,02687918 ! histidine catabolic process GO:0006548 6 6 0,000 4,878E-03 0,02683776 GO:0009077|histidine family amino acid catabolic process, ! centromeric heterochromatin GO:0005721 6 6 0,000 4,878E-03 0,02679647 ! mitochondrial respiratory chain complex assembly GO:0033108 6 6 0,000 4,878E-03 0,02675531 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 6 6 0,000 4,878E-03 0,02671428 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 6 6 0,000 4,878E-03 0,02667337 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 6 6 0,000 4,878E-03 0,02663258 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 6 0,000 4,878E-03 0,02659192 ! microtubule nucleation GO:0007020 6 6 0,000 4,878E-03 0,02655139 ! proline biosynthetic process GO:0006561 7 6 0,000 4,878E-03 0,02651097 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 4,878E-03 0,02647068 ! transforming growth factor beta receptor activity, type I GO:0005025 6 6 0,000 4,878E-03 0,02643051 ! phasic smooth muscle contraction GO:0014821 6 6 0,000 4,878E-03 0,02639047 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 4,878E-03 0,02635054 ! peptidoglycan metabolic process GO:0000270 6 6 0,000 4,878E-03 0,02631074 GO:0009253|peptidoglycan catabolic process, ! cerebral cortex neuron differentiation GO:0021895 6 6 0,000 4,878E-03 0,02627105 ! paraxial mesoderm development GO:0048339 6 6 0,000 4,878E-03 0,02623149 ! melanosome organization GO:0032438 6 6 0,000 4,878E-03 0,02619204 ! mitochondrial outer membrane translocase complex GO:0005742 6 6 0,000 4,878E-03 0,02615272 ! flotillin complex GO:0016600 6 6 0,000 4,878E-03 0,02611351 ! positive regulation of neuroblast proliferation GO:0002052 6 6 0,000 4,878E-03 0,02607441 ! positive regulation of vasoconstriction GO:0045907 6 6 0,000 4,878E-03 0,02603544 ! negative regulation of DNA recombination GO:0045910 6 6 0,000 4,878E-03 0,02599658 ! positive regulation of exocytosis GO:0045921 7 6 0,000 4,878E-03 0,02595784 ! protein tyrosine kinase activator activity GO:0030296 6 6 0,000 4,878E-03 0,02591921 ! positive regulation of fatty acid metabolic process GO:0045923 6 6 0,000 4,878E-03 0,0258807 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 4,878E-03 0,0258423 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of mitotic cell cycle GO:0045931 6 6 0,000 4,878E-03 0,02580401 ! nonhomologous end joining complex GO:0070419 6 6 0,000 4,878E-03 0,02576584 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! DNA damage response, signal transduction resulting in transcription GO:0042772 9 6 0,000 4,878E-03 0,02572778 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! vinculin binding GO:0017166 6 6 0,000 4,878E-03 0,02568984 ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 4,878E-03 0,025652 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 4,878E-03 0,02561428 ! sodium ion homeostasis GO:0055078 6 6 0,000 4,878E-03 0,02557666 ! protein heterooligomerization GO:0051291 6 6 0,000 4,878E-03 0,02553916 ! negative regulation of gliogenesis GO:0014014 6 6 0,000 4,878E-03 0,02550177 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 8 6 0,000 4,878E-03 0,02546449 ! translation termination factor activity GO:0008079 6 6 0,000 4,878E-03 0,02542731 GO:0003747|translation release factor activity, ! centrosome duplication GO:0051298 6 6 0,000 4,878E-03 0,02539025 ! astrocyte development GO:0014002 6 6 0,000 4,878E-03 0,02535329 ! protein targeting to lysosome GO:0006622 6 6 0,000 4,878E-03 0,02531644 ! purine base biosynthetic process GO:0009113 7 6 0,000 4,878E-03 0,02527969 ! fibrinolysis GO:0042730 7 6 0,000 4,878E-03 0,02524306 ! peptidyl-asparagine modification GO:0018196 6 6 0,000 4,878E-03 0,02520652 GO:0018279|protein amino acid N-linked glycosylation via asparagine, GO:0004579|dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ! eating behavior GO:0042755 6 6 0,000 4,878E-03 0,0251701 ! B cell lineage commitment GO:0002326 6 6 0,000 4,878E-03 0,02513378 ! thiamin and derivative metabolic process GO:0042723 6 6 0,000 4,878E-03 0,02509756 ! response to exogenous dsRNA GO:0043330 6 6 0,000 4,878E-03 0,02506145 ! melanosome transport GO:0032402 6 6 0,000 4,878E-03 0,02502544 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 6 6 0,000 4,878E-03 0,02498954 GO:0014066|regulation of phosphoinositide 3-kinase cascade, ! mast cell activation GO:0045576 6 6 0,000 4,878E-03 0,02495374 ! regulation of dopamine secretion GO:0014059 6 6 0,000 4,878E-03 0,02491804 ! regulation of protein kinase B signaling cascade GO:0051896 6 6 0,000 4,878E-03 0,02488244 ! negative regulation of focal adhesion formation GO:0051895 8 6 0,000 4,878E-03 0,02484695 ! nucleoside catabolic process GO:0009164 7 6 0,000 4,878E-03 0,02481155 ! transcription initiation factor activity GO:0016986 6 6 0,000 4,878E-03 0,02477626 ! negative regulation of T cell differentiation GO:0045581 6 6 0,000 4,878E-03 0,02474106 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 4,878E-03 0,02470597 ! Schwann cell development GO:0014044 6 6 0,000 4,878E-03 0,02467098 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 6 0,000 4,878E-03 0,02463608 ! G-protein coupled photoreceptor activity GO:0008020 6 6 0,000 4,878E-03 0,02460128 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 4,878E-03 0,02456658 ! regulation of chondrocyte differentiation GO:0032330 6 6 0,000 4,878E-03 0,02453198 ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 4,878E-03 0,02449748 ! superoxide-generating NADPH oxidase activity GO:0016175 6 6 0,000 4,878E-03 0,02446307 ! nuclear envelope lumen GO:0005641 6 6 0,000 4,878E-03 0,02442876 ! RNA polymerase II transcription elongation factor activity GO:0016944 7 6 0,000 4,878E-03 0,02439455 ! regulation of meiosis GO:0040020 6 6 0,000 4,878E-03 0,02436043 GO:0051445|regulation of meiotic cell cycle, ! establishment of nucleus localization GO:0040023 8 6 0,000 4,878E-03 0,02432641 ! lipoxygenase activity GO:0016165 6 6 0,000 4,878E-03 0,02429248 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 4,878E-03 0,02425865 ! alpha DNA polymerase:primase complex GO:0005658 7 6 0,000 4,878E-03 0,02422491 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 4,878E-03 0,02419126 ! nuclear origin of replication recognition complex GO:0005664 6 6 0,000 4,878E-03 0,02415771 GO:0000808|origin recognition complex, ! DNA replication factor A complex GO:0005662 6 6 0,000 4,878E-03 0,02412425 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 4,878E-03 0,02409088 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 4,878E-03 0,02405761 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 4,878E-03 0,02402443 ! chromatin silencing complex GO:0005677 6 6 0,000 4,878E-03 0,02399133 GO:0034979|NAD-dependent protein deacetylase activity, GO:0017136|NAD-dependent histone deacetylase activity, ! U12-type spliceosomal complex GO:0005689 7 6 0,000 4,878E-03 0,02395833 ! B cell homeostasis GO:0001782 7 6 0,000 4,878E-03 0,02392542 ! regulation of respiratory burst GO:0060263 6 6 0,000 4,878E-03 0,0238926 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 10 6 0,000 4,878E-03 0,02385987 GO:0002820|negative regulation of adaptive immune response, ! immunological synapse GO:0001772 6 6 0,000 4,878E-03 0,02382723 ! MutLalpha complex GO:0032389 6 6 0,000 4,878E-03 0,02379468 ! leading edge membrane GO:0031256 6 6 0,000 4,878E-03 0,02376222 ! bis(5'-adenosyl)-triphosphatase activity GO:0047710 6 6 0,000 4,878E-03 0,02372985 ! peptidyl-histidine modification GO:0018202 6 6 0,000 4,878E-03 0,02369756 ! COPII vesicle coat GO:0030127 6 6 0,000 4,878E-03 0,02366537 GO:0012507|ER to Golgi transport vesicle membrane, ! peptidyl-threonine modification GO:0018210 6 6 0,000 4,878E-03 0,02363325 ! diuresis GO:0030146 6 6 0,000 4,878E-03 0,02360123 GO:0030147|natriuresis, ! glutathione biosynthetic process GO:0006750 6 6 0,000 4,878E-03 0,02356929 ! HLA-B specific inhibitory MHC class I receptor activity GO:0030109 6 6 0,000 4,878E-03 0,02353744 ! BBSome GO:0034464 6 6 0,000 4,878E-03 0,02350568 ! regulation of keratinocyte differentiation GO:0045616 6 6 0,000 4,878E-03 0,023474 ! glycerophosphodiester phosphodiesterase activity GO:0008889 6 6 0,000 4,878E-03 0,02344241 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 4,878E-03 0,0234109 ! sodium channel regulator activity GO:0017080 6 6 0,000 4,878E-03 0,02337947 ! glycolipid catabolic process GO:0019377 6 6 0,000 4,878E-03 0,02334813 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 6 6 0,000 4,878E-03 0,02331688 ! nicotinamide nucleotide biosynthetic process GO:0019359 6 6 0,000 4,878E-03 0,02328571 ! porphyrin catabolic process GO:0006787 8 6 0,000 4,878E-03 0,02325462 GO:0033015|tetrapyrrole catabolic process, ! removal of superoxide radicals GO:0019430 6 6 0,000 4,878E-03 0,02322361 ! positive regulation of glucose import GO:0046326 7 6 0,000 4,878E-03 0,02319269 GO:0010828|positive regulation of glucose transport, ! triglyceride catabolic process GO:0019433 6 6 0,000 4,878E-03 0,02316185 ! myeloid cell homeostasis GO:0002262 6 6 0,000 4,878E-03 0,02313109 ! lamin binding GO:0005521 6 6 0,000 4,878E-03 0,02310041 ! ectodermal gut morphogenesis GO:0048567 6 6 0,000 4,878E-03 0,02306981 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 6 6 0,000 4,878E-03 0,0230393 ! pattern recognition receptor signaling pathway GO:0002221 6 6 0,000 4,878E-03 0,02300886 ! negative regulation of calcium ion transport GO:0051926 6 6 0,000 4,878E-03 0,02297851 ! peroxiredoxin activity GO:0051920 6 6 0,000 4,878E-03 0,02294823 ! complement binding GO:0001848 8 6 0,000 4,878E-03 0,02291804 ! catecholamine transport GO:0051937 6 6 0,000 4,878E-03 0,02288792 ! regulation of sensory perception GO:0051931 6 6 0,000 4,878E-03 0,02285789 GO:0051930|regulation of sensory perception of pain, ! muscle adaptation GO:0043500 6 6 0,000 4,878E-03 0,02282793 ! hemopoietic progenitor cell differentiation GO:0002244 6 6 0,000 4,878E-03 0,02279805 ! dipeptidase activity GO:0016805 6 6 0,000 4,878E-03 0,02276825 ! ether hydrolase activity GO:0016803 6 6 0,000 4,878E-03 0,02273852 ! FACIT collagen GO:0005593 6 6 0,000 4,878E-03 0,02270888 ! actin filament polymerization GO:0030041 8 6 0,000 4,878E-03 0,02267931 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 4,878E-03 0,02264982 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 6 6 0,000 4,878E-03 0,0226204 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 6 0,000 4,878E-03 0,02259106 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 4,878E-03 0,0225618 ! negative regulation of synaptic transmission GO:0050805 7 6 0,000 4,878E-03 0,02253261 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 4,878E-03 0,0225035 ! organ regeneration GO:0031100 6 6 0,000 4,878E-03 0,02247446 ! Golgi transport complex GO:0017119 6 6 0,000 4,878E-03 0,0224455 ! sheet-forming collagen GO:0030935 6 6 0,000 4,878E-03 0,02241661 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 4,878E-03 0,0223878 ! positive regulation of coagulation GO:0050820 7 6 0,000 4,878E-03 0,02235906 ! defense response to Gram-negative bacterium GO:0050829 6 6 0,000 4,878E-03 0,0223304 ! positive regulation of MHC class II biosynthetic process GO:0045348 6 6 0,000 4,878E-03 0,0223018 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 6 6 0,000 4,878E-03 0,02227328 ! thioredoxin-disulfide reductase activity GO:0004791 6 6 0,000 4,878E-03 0,02224484 ! sphingomyelin phosphodiesterase activity GO:0004767 7 6 0,000 4,878E-03 0,02221647 ! regulation of cGMP metabolic process GO:0030823 6 6 0,000 4,878E-03 0,02218816 ! myoblast cell fate commitment GO:0048625 6 6 0,000 4,878E-03 0,02215993 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 4,878E-03 0,02213178 ! DNA synthesis during DNA repair GO:0000731 7 6 0,000 4,878E-03 0,02210369 ! neutral lipid biosynthetic process GO:0046460 6 6 0,000 4,878E-03 0,02207568 GO:0046463|acylglycerol biosynthetic process, ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 6 6 0,000 4,878E-03 0,02204773 ! nuclear telomere cap complex GO:0000783 6 6 0,000 4,878E-03 0,02201986 GO:0000782|telomere cap complex, ! Golgi to endosome transport GO:0006895 6 6 0,000 4,878E-03 0,02199206 ! negative regulation of JAK-STAT cascade GO:0046426 7 6 0,000 4,878E-03 0,02196432 ! sterol carrier activity GO:0005498 6 6 0,000 4,878E-03 0,02193666 ! positive regulation of cell-cell adhesion GO:0022409 6 6 0,000 4,878E-03 0,02190907 ! succinate metabolic process GO:0006105 6 6 0,000 4,878E-03 0,02188154 ! myelin sheath GO:0043209 6 6 0,000 4,878E-03 0,02185409 ! perikaryon GO:0043204 7 6 0,000 4,878E-03 0,0218267 ! oxaloacetate metabolic process GO:0006107 7 6 0,000 4,878E-03 0,02179939 ! malate metabolic process GO:0006108 6 6 0,000 4,878E-03 0,02177214 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 6 6 0,000 4,878E-03 0,02174495 ! posttranscriptional gene silencing by RNA GO:0035194 6 6 0,000 4,878E-03 0,02171784 GO:0016441|posttranscriptional gene silencing, ! mating behavior GO:0007617 6 6 0,000 4,878E-03 0,0216908 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 4,878E-03 0,02166382 ! rhythmic behavior GO:0007622 7 6 0,000 4,878E-03 0,02163691 ! copulation GO:0007620 6 6 0,000 4,878E-03 0,02161006 ! erythrocyte maturation GO:0043249 6 6 0,000 4,878E-03 0,02158328 ! equilibrioception GO:0050957 6 6 0,000 4,878E-03 0,02155657 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 4,878E-03 0,02152992 ! G-protein coupled receptor kinase activity GO:0004703 6 6 0,000 4,878E-03 0,02150334 ! chemosensory behavior GO:0007635 6 6 0,000 4,878E-03 0,02147683 ! synaptic transmission, dopaminergic GO:0001963 7 6 0,000 4,878E-03 0,02145038 ! mechanosensory behavior GO:0007638 6 6 0,000 4,878E-03 0,021424 ! response to interferon-gamma GO:0034341 6 6 0,000 4,878E-03 0,02139768 ! spinal cord patterning GO:0021511 6 6 0,000 4,878E-03 0,02137142 ! cGMP-mediated signaling GO:0019934 6 6 0,000 4,878E-03 0,02134523 ! protein geranylgeranyltransferase activity GO:0004661 6 6 0,000 4,878E-03 0,0213191 ! activation of MAPKKK activity GO:0000185 6 6 0,000 4,878E-03 0,02129304 ! nerve growth factor receptor signaling pathway GO:0048011 8 6 0,000 4,878E-03 0,02126704 ! glucosyltransferase activity GO:0046527 6 6 0,000 4,878E-03 0,02124111 ! sphingoid catabolic process GO:0046521 6 6 0,000 4,878E-03 0,02121524 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 4,878E-03 0,02118943 ! activin receptor activity GO:0017002 6 6 0,000 4,878E-03 0,02116368 ! ovulation GO:0030728 6 6 0,000 4,878E-03 0,021138 ! dopamine binding GO:0035240 7 6 0,000 4,878E-03 0,02111237 ! hyperosmotic response GO:0006972 6 6 0,000 4,878E-03 0,02108681 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 6 6 0,000 4,878E-03 0,02106132 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 6 0,000 4,878E-03 0,02103588 ! nuclear localization sequence binding GO:0008139 6 6 0,000 4,878E-03 0,02101051 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 4,878E-03 0,02098519 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 4,878E-03 0,02095994 ! copper ion transmembrane transporter activity GO:0005375 6 6 0,000 4,878E-03 0,02093475 ! poly(A) RNA binding GO:0008143 6 6 0,000 4,878E-03 0,02090961 ! positive transcription elongation factor activity GO:0008159 6 6 0,000 4,878E-03 0,02088454 ! regulation of glycogen metabolic process GO:0070873 7 6 0,000 4,878E-03 0,02085953 GO:0032881|regulation of polysaccharide metabolic process, ! maintenance of protein location in nucleus GO:0051457 6 6 0,000 4,878E-03 0,02083458 ! intracellular pH reduction GO:0051452 6 6 0,000 4,878E-03 0,02080969 GO:0045851|pH reduction, ! purine salvage GO:0043101 8 6 0,000 4,878E-03 0,02078486 ! nucleotide-sugar transmembrane transporter activity GO:0005338 6 6 0,000 4,878E-03 0,02076008 ! neurotrophin binding GO:0043121 6 6 0,000 4,878E-03 0,02073537 ! ciliary rootlet GO:0035253 6 6 0,000 4,878E-03 0,02071071 ! neurotransmitter catabolic process GO:0042135 10 6 0,000 4,878E-03 0,02068611 ! ruffle organization GO:0031529 6 6 0,000 4,878E-03 0,02066158 ! T cell mediated immunity GO:0002456 6 6 0,000 4,878E-03 0,0206371 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 7 6 0,000 4,878E-03 0,02061267 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! carnitine transport GO:0015879 6 6 0,000 4,878E-03 0,02058831 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 4,878E-03 0,020564 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! palmitoyl-CoA hydrolase activity GO:0016290 6 6 0,000 4,878E-03 0,02053975 ! S-methyltransferase activity GO:0008172 6 6 0,000 4,878E-03 0,02051556 ! phospholipase D activity GO:0004630 6 6 0,000 4,878E-03 0,02049142 ! rRNA modification GO:0000154 6 6 0,000 4,878E-03 0,02046734 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 4,878E-03 0,02044332 ! neuronal ion channel clustering GO:0045161 6 6 0,000 4,878E-03 0,02041935 ! response to UV-B GO:0010224 6 6 0,000 4,878E-03 0,02039544 ! interaction with symbiont GO:0051702 6 6 0,000 4,878E-03 0,02037159 ! negative regulation of insulin receptor signaling pathway GO:0046627 6 6 0,000 4,878E-03 0,02034779 ! IgG binding GO:0019864 6 6 0,000 4,878E-03 0,02032405 ! positive regulation of cytokine production during immune response GO:0002720 6 6 0,000 4,878E-03 0,02030036 ! base-excision repair, AP site formation GO:0006285 6 6 0,000 4,878E-03 0,02027673 ! benzodiazepine receptor activity GO:0008503 6 6 0,000 4,878E-03 0,02025315 ! response to copper ion GO:0046688 6 6 0,000 4,878E-03 0,02022963 ! DNA topological change GO:0006265 6 6 0,000 4,878E-03 0,02020616 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 4,878E-03 0,02018274 ! dendrite morphogenesis GO:0048813 6 6 0,000 4,878E-03 0,02015939 ! regulation of interleukin-1 beta production GO:0032651 6 6 0,000 4,878E-03 0,02013608 ! regulation of myeloid cell apoptosis GO:0033032 6 6 0,000 4,878E-03 0,02011283 ! positive regulation of tumor necrosis factor production GO:0032760 6 6 0,000 4,878E-03 0,02008963 ! nucleosome disassembly GO:0006337 6 6 0,000 4,878E-03 0,02006648 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! inositol trisphosphate 3-kinase activity GO:0008440 6 6 0,000 4,878E-03 0,02004339 ! regulation of mast cell activation GO:0033003 6 6 0,000 4,878E-03 0,02002035 ! guanylyltransferase activity GO:0070568 6 6 0,000 4,878E-03 0,01999737 ! receptor internalization GO:0031623 7 6 0,000 4,878E-03 0,01997444 ! neuropeptide Y receptor activity GO:0004983 6 6 0,000 4,878E-03 0,01995156 ! ATP-dependent peptidase activity GO:0004176 6 6 0,000 4,878E-03 0,01992873 ! serine-type carboxypeptidase activity GO:0004185 6 6 0,000 4,878E-03 0,01990595 GO:0070008|serine-type exopeptidase activity, ! protein deubiquitination GO:0016579 6 6 0,000 4,878E-03 0,01988323 ! negative regulation of neuroblast proliferation GO:0007406 6 6 0,000 4,878E-03 0,01986056 ! NuRD complex GO:0016581 6 6 0,000 4,878E-03 0,01983794 ! nucleosome positioning GO:0016584 6 6 0,000 4,878E-03 0,01981537 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 4,878E-03 0,01979285 ! alpha-adrenergic receptor activity GO:0004936 8 6 0,000 4,878E-03 0,01977038 ! glycine binding GO:0016594 8 6 0,000 4,878E-03 0,01974797 ! costamere GO:0043034 7 6 0,000 4,878E-03 0,0197256 ! A band GO:0031672 6 6 0,000 4,878E-03 0,01970329 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 4,878E-03 0,01968103 ! dopamine biosynthetic process GO:0042416 7 6 0,000 4,878E-03 0,01965881 ! procollagen-proline dioxygenase activity GO:0019798 6 6 0,000 4,878E-03 0,01963665 ! negative regulation of axon extension GO:0030517 6 6 0,000 4,878E-03 0,01961454 ! actin monomer binding GO:0003785 6 6 0,000 4,878E-03 0,01959247 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 4,878E-03 0,01957046 ! lysozyme activity GO:0003796 6 6 0,000 4,878E-03 0,01954849 ! regulation of Rac protein signal transduction GO:0035020 6 6 0,000 4,878E-03 0,01952658 ! ATP catabolic process GO:0006200 6 6 0,000 4,878E-03 0,01950471 ! determination of adult lifespan GO:0008340 6 6 0,000 4,878E-03 0,0194829 ! somatic stem cell maintenance GO:0035019 6 6 0,000 4,878E-03 0,01946113 ! negative regulation of organic acid transport GO:0032891 6 6 0,000 4,878E-03 0,01943941 ! establishment of apical/basal cell polarity GO:0035089 6 6 0,000 4,878E-03 0,01941774 ! calcium-dependent phospholipase A2 activity GO:0047498 6 6 0,000 4,878E-03 0,01939611 ! O-acetyltransferase activity GO:0016413 6 6 0,000 4,878E-03 0,01937454 ! CoA-ligase activity GO:0016405 6 6 0,000 4,878E-03 0,01935301 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 4,878E-03 0,01933153 ! IkappaB kinase complex GO:0008385 6 6 0,000 4,878E-03 0,0193101 ! pyrimidine nucleotide catabolic process GO:0006244 6 6 0,000 4,878E-03 0,01928871 ! store-operated calcium channel activity GO:0015279 6 6 0,000 4,878E-03 0,01926738 ! aminomethyltransferase activity GO:0004047 6 6 0,000 4,878E-03 0,01924609 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 6 6 0,000 4,878E-03 0,01922484 ! alkaline phosphatase activity GO:0004035 6 6 0,000 4,878E-03 0,01920365 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 6 6 0,000 4,878E-03 0,0191825 ! oligosaccharide biosynthetic process GO:0009312 7 7 0,000 5,688E-03 0,02234662 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 5,688E-03 0,02232206 ! sleep GO:0030431 7 7 0,000 5,688E-03 0,02229756 ! synaptonemal complex assembly GO:0007130 7 7 0,000 5,688E-03 0,02227311 GO:0070193|synaptonemal complex organization, ! forebrain regionalization GO:0021871 7 7 0,000 5,688E-03 0,02224872 ! cell proliferation in forebrain GO:0021846 7 7 0,000 5,688E-03 0,02222437 ! proteasome regulatory particle GO:0005838 8 7 0,000 5,688E-03 0,02220008 ! meiotic prophase I GO:0007128 7 7 0,000 5,688E-03 0,02217585 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 7 0,000 5,688E-03 0,02215167 ! SMAD protein nuclear translocation GO:0007184 8 7 0,000 5,688E-03 0,02212754 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 7 7 0,000 5,688E-03 0,02210346 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 5,688E-03 0,02207943 ! diphosphotransferase activity GO:0016778 8 7 0,000 5,688E-03 0,02205546 ! actin-myosin filament sliding GO:0033275 7 7 0,000 5,688E-03 0,02203154 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! signal peptide processing GO:0006465 7 7 0,000 5,688E-03 0,02200767 ! glycine hydroxymethyltransferase activity GO:0004372 8 7 0,000 5,688E-03 0,02198385 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 5,688E-03 0,02196008 ! macrophage chemotaxis GO:0048246 7 7 0,000 5,688E-03 0,02193637 ! cerebral cortex cell migration GO:0021795 7 7 0,000 5,688E-03 0,0219127 ! tachykinin receptor signaling pathway GO:0007217 7 7 0,000 5,688E-03 0,02188909 ! membrane hyperpolarization GO:0060081 7 7 0,000 5,688E-03 0,02186553 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 5,688E-03 0,02184202 ! enoyl-CoA hydratase activity GO:0004300 7 7 0,000 5,688E-03 0,02181856 ! DNA replication origin binding GO:0003688 7 7 0,000 5,688E-03 0,02179515 ! ATPase binding GO:0051117 7 7 0,000 5,688E-03 0,02177179 ! positive regulation of glycolysis GO:0045821 7 7 0,000 5,688E-03 0,02174848 ! positive regulation of isotype switching GO:0045830 11 7 0,000 5,688E-03 0,02172522 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 8 7 0,000 5,688E-03 0,02170201 ! ribonucleoside triphosphate catabolic process GO:0009203 7 7 0,000 5,688E-03 0,02167884 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! protein-cofactor linkage GO:0018065 7 7 0,000 5,688E-03 0,02165573 ! positive regulation of chemokine biosynthetic process GO:0045080 7 7 0,000 5,688E-03 0,02163267 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 7 7 0,000 5,688E-03 0,02160966 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! thymic T cell selection GO:0045061 11 7 0,000 5,688E-03 0,02158669 ! structural constituent of tooth enamel GO:0030345 7 7 0,000 5,688E-03 0,02156378 ! transepithelial chloride transport GO:0030321 7 7 0,000 5,688E-03 0,02154091 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 5,688E-03 0,02151809 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 5,688E-03 0,02149532 ! glycine catabolic process GO:0006546 7 7 0,000 5,688E-03 0,0214726 GO:0009071|serine family amino acid catabolic process, ! deoxyribonucleotide biosynthetic process GO:0009263 8 7 0,000 5,688E-03 0,02144992 ! cytoskeletal anchoring at plasma membrane GO:0007016 8 7 0,000 5,688E-03 0,0214273 ! response to pH GO:0009268 7 7 0,000 5,688E-03 0,02140472 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 5,688E-03 0,02138219 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! polyamine biosynthetic process GO:0006596 7 7 0,000 5,688E-03 0,0213597 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 7 7 0,000 5,688E-03 0,02133727 ! endosome organization GO:0007032 7 7 0,000 5,688E-03 0,02131488 ! thyroid hormone generation GO:0006590 7 7 0,000 5,688E-03 0,02129253 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 5,688E-03 0,02127024 GO:0021940|positive regulation of granule cell precursor proliferation, ! reverse cholesterol transport GO:0043691 7 7 0,000 5,688E-03 0,02124799 ! tumor necrosis factor receptor activity GO:0005031 7 7 0,000 5,688E-03 0,02122579 ! indolalkylamine metabolic process GO:0006586 7 7 0,000 5,688E-03 0,02120363 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! proton-transporting V-type ATPase, V1 domain GO:0033180 7 7 0,000 5,688E-03 0,02118152 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 5,688E-03 0,02115946 ! retinoid X receptor binding GO:0046965 7 7 0,000 5,688E-03 0,02113744 ! central nervous system neuron axonogenesis GO:0021955 7 7 0,000 5,688E-03 0,02111546 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 5,688E-03 0,02109354 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! platelet-derived growth factor receptor activity GO:0005017 7 7 0,000 5,688E-03 0,02107166 ! urea metabolic process GO:0019627 7 7 0,000 5,688E-03 0,02104982 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! retinoic acid receptor signaling pathway GO:0048384 7 7 0,000 5,688E-03 0,02102803 ! regulation of type I interferon production GO:0032479 8 7 0,000 5,688E-03 0,02100628 ! peroxisomal matrix GO:0005782 7 7 0,000 5,688E-03 0,02098458 GO:0031907|microbody lumen, ! methyltransferase complex GO:0034708 7 7 0,000 5,688E-03 0,02096293 GO:0035097|histone methyltransferase complex, ! response to dietary excess GO:0002021 7 7 0,000 5,688E-03 0,02094132 ! p53 binding GO:0002039 7 7 0,000 5,688E-03 0,02091975 ! osteoblast development GO:0002076 8 7 0,000 5,688E-03 0,02089823 ! positive regulation of nitric-oxide synthase activity GO:0051000 7 7 0,000 5,688E-03 0,02087675 ! lipid phosphatase activity GO:0042577 7 7 0,000 5,688E-03 0,02085532 ! male sex determination GO:0030238 7 7 0,000 5,688E-03 0,02083393 ! clathrin binding GO:0030276 8 7 0,000 5,688E-03 0,02081258 ! negative regulation of translational initiation GO:0045947 7 7 0,000 5,688E-03 0,02079128 ! determination of anterior/posterior axis, embryo GO:0008595 7 7 0,000 5,688E-03 0,02077002 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 7 7 0,000 5,688E-03 0,0207488 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 5,688E-03 0,02072763 GO:0030204|chondroitin sulfate metabolic process, ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 5,688E-03 0,0207065 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 5,688E-03 0,02068541 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 5,688E-03 0,02066437 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 5,688E-03 0,02064337 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 8 7 0,000 5,688E-03 0,02062241 ! hyaluronan metabolic process GO:0030212 8 7 0,000 5,688E-03 0,0206015 ! protein retention in ER lumen GO:0006621 7 7 0,000 5,688E-03 0,02058063 ! cardiac muscle cell differentiation GO:0055007 7 7 0,000 5,688E-03 0,02055979 ! peptidyl-arginine modification GO:0018195 7 7 0,000 5,688E-03 0,02053901 ! regulation of circadian rhythm GO:0042752 7 7 0,000 5,688E-03 0,02051826 ! Hsp90 protein binding GO:0051879 7 7 0,000 5,688E-03 0,02049756 ! MutSalpha complex binding GO:0032407 8 7 0,000 5,688E-03 0,02047689 ! regulation of fat cell differentiation GO:0045598 7 7 0,000 5,688E-03 0,02045627 ! establishment of melanosome localization GO:0032401 7 7 0,000 5,688E-03 0,02043569 ! gas homeostasis GO:0033483 7 7 0,000 5,688E-03 0,02041515 ! cranial nerve morphogenesis GO:0021602 7 7 0,000 5,688E-03 0,02039466 ! subpallium development GO:0021544 7 7 0,000 5,688E-03 0,0203742 ! laminin-1 complex GO:0005606 7 7 0,000 5,688E-03 0,02035378 GO:0043256|laminin complex, ! molybdopterin cofactor biosynthetic process GO:0032324 7 7 0,000 5,688E-03 0,02033341 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 8 7 0,000 5,688E-03 0,02031308 ! eye photoreceptor cell differentiation GO:0001754 10 7 0,000 5,688E-03 0,02029278 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 7 7 0,000 5,688E-03 0,02027253 ! positive regulation of immunoglobulin mediated immune response GO:0002891 11 7 0,000 5,688E-03 0,02025232 GO:0002714|positive regulation of B cell mediated immunity, ! protein sumoylation GO:0016925 7 7 0,000 5,688E-03 0,02023215 ! establishment of chromosome localization GO:0051303 7 7 0,000 5,688E-03 0,02021202 GO:0050000|chromosome localization, ! regulation of lipid transport GO:0032368 7 7 0,000 5,688E-03 0,02019193 ! regulation of cell division GO:0051302 7 7 0,000 5,688E-03 0,02017187 ! chromatin assembly complex GO:0005678 7 7 0,000 5,688E-03 0,02015186 ! sex chromatin GO:0001739 7 7 0,000 5,688E-03 0,02013189 GO:0000803|sex chromosome, ! oligosaccharyl transferase activity GO:0004576 7 7 0,000 5,688E-03 0,02011196 ! chitinase activity GO:0004568 7 7 0,000 5,688E-03 0,02009206 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 7 7 0,000 5,688E-03 0,02007221 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 7 7 0,000 5,688E-03 0,0200524 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 10 7 0,000 5,688E-03 0,02003262 ! inhibitory MHC class I receptor activity GO:0032396 7 7 0,000 5,688E-03 0,02001288 GO:0030110|HLA-C specific inhibitory MHC class I receptor activity, ! ER to Golgi transport vesicle GO:0030134 7 7 0,000 5,688E-03 0,01999319 ! molybdenum ion binding GO:0030151 7 7 0,000 5,688E-03 0,01997353 ! centriolar satellite GO:0034451 8 7 0,000 5,688E-03 0,01995391 ! positive regulation of epidermis development GO:0045684 7 7 0,000 5,688E-03 0,01993433 ! proteasome regulator activity GO:0010860 7 7 0,000 5,688E-03 0,01991478 ! antibiotic transport GO:0042891 7 7 0,000 5,688E-03 0,01989528 ! negative regulation of transmission of nerve impulse GO:0051970 8 7 0,000 5,688E-03 0,01987581 ! regulation of synaptic transmission, glutamatergic GO:0051966 7 7 0,000 5,688E-03 0,01985638 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 5,688E-03 0,01983699 ! aspartate family amino acid catabolic process GO:0009068 7 7 0,000 5,688E-03 0,01981764 ! Wnt receptor activity GO:0042813 7 7 0,000 5,688E-03 0,01979832 ! regulation of protein homodimerization activity GO:0043496 7 7 0,000 5,688E-03 0,01977904 ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 7 7 0,000 5,688E-03 0,0197598 ! positive regulation of viral reproduction GO:0048524 7 7 0,000 5,688E-03 0,0197406 ! negative regulation of viral reproduction GO:0048525 7 7 0,000 5,688E-03 0,01972143 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 9 7 0,000 5,688E-03 0,01970231 ! blastocyst growth GO:0001832 7 7 0,000 5,688E-03 0,01968321 ! pigment granule transport GO:0051904 7 7 0,000 5,688E-03 0,01966416 ! lymphocyte activation during immune response GO:0002285 7 7 0,000 5,688E-03 0,01964514 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 5,688E-03 0,01962616 ! negative regulation of fibrinolysis GO:0051918 7 7 0,000 5,688E-03 0,01960722 ! negative regulation of telomere maintenance GO:0032205 7 7 0,000 5,688E-03 0,01958831 ! cerebellar cortex formation GO:0021697 8 7 0,000 5,688E-03 0,01956944 ! activation of innate immune response GO:0002218 7 7 0,000 5,688E-03 0,0195506 GO:0002758|innate immune response-activating signal transduction, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 7 7 0,000 5,688E-03 0,0195318 ! natural killer cell mediated immunity GO:0002228 7 7 0,000 5,688E-03 0,01951304 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of synaptic transmission, dopaminergic GO:0032225 7 7 0,000 5,688E-03 0,01949432 ! regulation of synaptic transmission, GABAergic GO:0032228 7 7 0,000 5,688E-03 0,01947563 ! flavin-containing monooxygenase activity GO:0004499 7 7 0,000 5,688E-03 0,01945697 ! regulation of muscle adaptation GO:0043502 7 7 0,000 5,688E-03 0,01943835 ! sequestering of metal ion GO:0051238 7 7 0,000 5,688E-03 0,01941977 ! regulation of T cell receptor signaling pathway GO:0050856 8 7 0,000 5,688E-03 0,01940122 ! membrane attack complex GO:0005579 7 7 0,000 5,688E-03 0,01938271 ! fibrinogen complex GO:0005577 7 7 0,000 5,688E-03 0,01936423 ! septin complex GO:0031105 9 7 0,000 5,688E-03 0,01934579 GO:0032156|septin cytoskeleton, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 7 7 0,000 5,688E-03 0,01932738 ! positive regulation of microtubule polymerization GO:0031116 7 7 0,000 5,688E-03 0,01930901 ! cellular anion homeostasis GO:0030002 7 7 0,000 5,688E-03 0,01929067 GO:0055081|anion homeostasis, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 7 7 0,000 5,688E-03 0,01927237 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! behavioral response to cocaine GO:0048148 9 7 0,000 5,688E-03 0,0192541 ! autophagic vacuole formation GO:0000045 8 7 0,000 5,688E-03 0,01923587 ! negative regulation of smooth muscle cell proliferation GO:0048662 7 7 0,000 5,688E-03 0,01921767 ! translation initiation factor binding GO:0031369 7 7 0,000 5,688E-03 0,01919951 ! regulation of lipid catabolic process GO:0050994 7 7 0,000 5,688E-03 0,01918138 ! activin binding GO:0048185 7 7 0,000 5,688E-03 0,01916328 ! syncytium formation by plasma membrane fusion GO:0000768 7 7 0,000 5,688E-03 0,01914522 GO:0007520|myoblast fusion, ! nucleotide-excision repair, DNA incision GO:0033683 7 7 0,000 5,688E-03 0,01912719 ! oligosaccharyltransferase complex GO:0008250 7 7 0,000 5,688E-03 0,0191092 ! phototransduction, visible light GO:0007603 7 7 0,000 5,688E-03 0,01909124 ! positive regulation of neurotransmitter transport GO:0051590 7 7 0,000 5,688E-03 0,01907331 ! lipoprotein transport GO:0042953 7 7 0,000 5,688E-03 0,01905542 ! cell division site part GO:0032155 7 7 0,000 5,688E-03 0,01903756 GO:0032153|cell division site, ! laminin binding GO:0043236 9 7 0,000 5,688E-03 0,01901974 ! detection of mechanical stimulus involved in sensory perception GO:0050974 7 7 0,000 5,688E-03 0,01900194 ! phospholipid efflux GO:0033700 7 7 0,000 5,688E-03 0,01898418 ! DNA insertion or deletion binding GO:0032135 7 7 0,000 5,688E-03 0,01896646 GO:0032138|single base insertion or deletion binding, ! glucocorticoid metabolic process GO:0008211 7 7 0,000 5,688E-03 0,01894877 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 7 7 0,000 5,688E-03 0,01893111 ! poly-purine tract binding GO:0070717 7 7 0,000 5,688E-03 0,01891348 ! T-helper 1 type immune response GO:0042088 7 7 0,000 5,688E-03 0,01889589 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 5,688E-03 0,01887832 GO:0032107|regulation of response to nutrient levels, ! amyloid precursor protein catabolic process GO:0042987 7 7 0,000 5,688E-03 0,0188608 ! leukocyte degranulation GO:0043299 7 7 0,000 5,688E-03 0,0188433 ! sodium:phosphate symporter activity GO:0005436 7 7 0,000 5,688E-03 0,01882584 ! bile acid and bile salt transport GO:0015721 7 7 0,000 5,688E-03 0,0188084 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 5,688E-03 0,01879101 ! glycerol ether biosynthetic process GO:0046504 7 7 0,000 5,688E-03 0,01877364 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 5,688E-03 0,0187563 GO:0046513|ceramide biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 5,688E-03 0,018739 ! pigment granule organization GO:0048753 7 7 0,000 5,688E-03 0,01872173 ! eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 7 7 0,000 5,688E-03 0,01870449 ! regulation of interleukin-8 biosynthetic process GO:0045414 8 7 0,000 5,688E-03 0,01868728 ! regulation of pigmentation during development GO:0048070 10 7 0,000 5,688E-03 0,01867011 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 7 7 0,000 5,688E-03 0,01865296 ! macrophage activation GO:0042116 7 7 0,000 5,688E-03 0,01863585 ! positive regulation of activated T cell proliferation GO:0042104 7 7 0,000 5,688E-03 0,01861877 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 7 7 0,000 5,688E-03 0,01860172 ! galactose metabolic process GO:0006012 7 7 0,000 5,688E-03 0,0185847 ! vesicle fusion GO:0006906 7 7 0,000 5,688E-03 0,01856771 ! positive regulation of insulin secretion GO:0032024 7 7 0,000 5,688E-03 0,01855076 ! glycerol ether catabolic process GO:0044269 7 7 0,000 5,688E-03 0,01853383 GO:0046464|acylglycerol catabolic process, ! virus-infected cell apoptosis GO:0006926 7 7 0,000 5,688E-03 0,01851693 ! NuA4 histone acetyltransferase complex GO:0035267 8 7 0,000 5,688E-03 0,01850007 ! nucleoside transmembrane transporter activity GO:0005337 7 7 0,000 5,688E-03 0,01848324 GO:0015858|nucleoside transport, ! regulation of vascular permeability GO:0043114 7 7 0,000 5,688E-03 0,01846643 ! regulation of multicellular organismal metabolic process GO:0044246 8 7 0,000 5,688E-03 0,01844966 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 5,688E-03 0,01843292 ! peptidyl-proline dioxygenase activity GO:0031543 7 7 0,000 5,688E-03 0,01841621 ! inclusion body GO:0016234 7 7 0,000 5,688E-03 0,01839953 ! parturition GO:0007567 7 7 0,000 5,688E-03 0,01838288 ! tRNA methyltransferase activity GO:0008175 7 7 0,000 5,688E-03 0,01836625 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 7 7 0,000 5,688E-03 0,01834966 ! intercalated disc GO:0014704 8 7 0,000 5,688E-03 0,0183331 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 5,688E-03 0,01831657 ! neural nucleus development GO:0048857 7 7 0,000 5,688E-03 0,01830007 ! intermediate filament organization GO:0045109 8 7 0,000 5,688E-03 0,0182836 ! skeletal muscle contraction GO:0003009 7 7 0,000 5,688E-03 0,01826716 ! response to antibiotic GO:0046677 7 7 0,000 5,688E-03 0,01825074 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 7 7 0,000 5,688E-03 0,01823436 ! preribosome GO:0030684 7 7 0,000 5,688E-03 0,01821801 ! positive regulation of production of molecular mediator of immune response GO:0002702 7 7 0,000 5,688E-03 0,01820168 ! hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 7 7 0,000 5,688E-03 0,01818539 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 7 7 0,000 5,688E-03 0,01816912 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 5,688E-03 0,01815288 ! regulation of interleukin-1 production GO:0032652 7 7 0,000 5,688E-03 0,01813668 ! phosphofructokinase activity GO:0008443 7 7 0,000 5,688E-03 0,0181205 ! postreplication repair GO:0006301 7 7 0,000 5,688E-03 0,01810435 ! gap junction channel activity GO:0005243 7 7 0,000 5,688E-03 0,01808823 ! transcription from RNA polymerase I promoter GO:0006360 7 7 0,000 5,688E-03 0,01807213 ! mitochondrion morphogenesis GO:0070584 8 7 0,000 5,688E-03 0,01805607 ! transcription termination GO:0006353 8 7 0,000 5,688E-03 0,01804003 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 7 7 0,000 5,688E-03 0,01802403 ! tetracycline transporter activity GO:0008493 7 7 0,000 5,688E-03 0,01800805 GO:0042895|antibiotic transporter activity, ! cytidylyltransferase activity GO:0070567 7 7 0,000 5,688E-03 0,0179921 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 5,688E-03 0,01797617 ! melanocortin receptor activity GO:0004977 7 7 0,000 5,688E-03 0,01796028 ! coenzyme A metabolic process GO:0015936 8 7 0,000 5,688E-03 0,01794441 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 7 0,000 5,688E-03 0,01792858 ! regulation of macrophage activation GO:0043030 7 7 0,000 5,688E-03 0,01791277 ! cytidine deaminase activity GO:0004126 7 7 0,000 5,688E-03 0,01789698 ! inositol trisphosphate kinase activity GO:0051766 7 7 0,000 5,688E-03 0,01788123 ! apical protein localization GO:0045176 7 7 0,000 5,688E-03 0,0178655 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 5,688E-03 0,0178498 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 5,688E-03 0,01783413 ! virion binding GO:0046790 10 7 0,000 5,688E-03 0,01781849 ! nonprotein amino acid metabolic process GO:0019794 7 7 0,000 5,688E-03 0,01780287 ! protein prenyltransferase activity GO:0008318 7 7 0,000 5,688E-03 0,01778728 ! protein modification by small protein removal GO:0070646 7 7 0,000 5,688E-03 0,01777172 ! adult feeding behavior GO:0008343 7 7 0,000 5,688E-03 0,01775619 ! CoA carboxylase activity GO:0016421 7 7 0,000 5,688E-03 0,01774068 ! microtubule basal body GO:0005932 7 7 0,000 5,688E-03 0,0177252 ! positive regulation of NF-kappaB import into nucleus GO:0042346 7 7 0,000 5,688E-03 0,01770974 ! embryonic heart tube development GO:0035050 7 7 0,000 5,688E-03 0,01769432 ! kainate selective glutamate receptor activity GO:0015277 7 7 0,000 5,688E-03 0,01767892 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 5,688E-03 0,01766355 ! positive regulation of smooth muscle contraction GO:0045987 7 7 0,000 5,688E-03 0,0176482 ! rRNA transcription GO:0009303 8 8 0,000 6,499E-03 0,02014434 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 8 8 0,000 6,499E-03 0,02012687 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 6,499E-03 0,02010943 ! sodium:hydrogen antiporter activity GO:0015385 8 8 0,000 6,499E-03 0,02009202 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cation:chloride symporter activity GO:0015377 9 8 0,000 6,499E-03 0,02007464 ! positive regulation of small GTPase mediated signal transduction GO:0051057 8 8 0,000 6,499E-03 0,02005729 GO:0046579|positive regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 8 0,000 6,499E-03 0,02003997 ! male meiosis GO:0007140 8 8 0,000 6,499E-03 0,02002268 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8 8 0,000 6,499E-03 0,02000542 ! N-glycan processing GO:0006491 8 8 0,000 6,499E-03 0,01998819 ! protein self-association GO:0043621 8 8 0,000 6,499E-03 0,01997098 ! RNA methylation GO:0001510 8 8 0,000 6,499E-03 0,01995381 ! prostaglandin biosynthetic process GO:0001516 9 8 0,000 6,499E-03 0,01993667 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 8 8 0,000 6,499E-03 0,01991956 ! regulation of activated T cell proliferation GO:0046006 8 8 0,000 6,499E-03 0,01990247 ! hexokinase activity GO:0004396 8 8 0,000 6,499E-03 0,01988542 ! neurofilament cytoskeleton GO:0060053 8 8 0,000 6,499E-03 0,01986839 ! guanylate cyclase activity GO:0004383 8 8 0,000 6,499E-03 0,0198514 ! integral to mitochondrial membrane GO:0032592 8 8 0,000 6,499E-03 0,01983443 ! troponin complex GO:0005861 9 8 0,000 6,499E-03 0,01981749 ! smoothened signaling pathway GO:0007224 8 8 0,000 6,499E-03 0,01980058 ! negative regulation of muscle cell differentiation GO:0051148 8 8 0,000 6,499E-03 0,0197837 ! ganglioside metabolic process GO:0001573 8 8 0,000 6,499E-03 0,01976685 ! reflex GO:0060004 11 8 0,000 6,499E-03 0,01975003 ! small protein activating enzyme activity GO:0008641 10 8 0,000 6,499E-03 0,01973323 ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 6,499E-03 0,01971647 ! hemoglobin metabolic process GO:0020027 8 8 0,000 6,499E-03 0,01969973 ! protein targeting to ER GO:0045047 9 8 0,000 6,499E-03 0,01968302 ! positive regulation of survival gene product expression GO:0045885 8 8 0,000 6,499E-03 0,01966634 ! arginine catabolic process GO:0006527 8 8 0,000 6,499E-03 0,01964969 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 6,499E-03 0,01963307 ! malate dehydrogenase activity GO:0016615 8 8 0,000 6,499E-03 0,01961647 ! inner mitochondrial membrane organization GO:0007007 9 8 0,000 6,499E-03 0,0195999 ! telomere maintenance via telomerase GO:0007004 8 8 0,000 6,499E-03 0,01958336 GO:0010833|telomere maintenance via telomere lengthening, ! DNA secondary structure binding GO:0000217 8 8 0,000 6,499E-03 0,01956685 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 9 8 0,000 6,499E-03 0,01955036 ! proline metabolic process GO:0006560 9 8 0,000 6,499E-03 0,01953391 ! melanosome membrane GO:0033162 10 8 0,000 6,499E-03 0,01951748 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 6,499E-03 0,01950108 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 6,499E-03 0,0194847 ! melanin metabolic process GO:0006582 9 8 0,000 6,499E-03 0,01946836 ! death receptor activity GO:0005035 8 8 0,000 6,499E-03 0,01945204 ! Golgi lumen GO:0005796 8 8 0,000 6,499E-03 0,01943575 ! smooth endoplasmic reticulum GO:0005790 9 8 0,000 6,499E-03 0,01941948 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 9 8 0,000 6,499E-03 0,01940325 GO:0048500|signal recognition particle, ! Golgi cisterna GO:0031985 9 8 0,000 6,499E-03 0,01938704 ! positive regulation of mesenchymal cell proliferation GO:0002053 8 8 0,000 6,499E-03 0,01937085 ! Rac protein signal transduction GO:0016601 8 8 0,000 6,499E-03 0,0193547 ! positive regulation of calcium ion transport into cytosol GO:0010524 11 8 0,000 6,499E-03 0,01933857 ! lens development in camera-type eye GO:0002088 8 8 0,000 6,499E-03 0,01932247 ! positive regulation of vasodilation GO:0045909 8 8 0,000 6,499E-03 0,01930639 ! intestinal cholesterol absorption GO:0030299 8 8 0,000 6,499E-03 0,01929034 ! negative regulation of muscle contraction GO:0045932 9 8 0,000 6,499E-03 0,01927432 ! positive regulation vascular endothelial growth factor production GO:0010575 8 8 0,000 6,499E-03 0,01925833 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 8 8 0,000 6,499E-03 0,01924236 ! Schwann cell differentiation GO:0014037 8 8 0,000 6,499E-03 0,01922642 ! sodium:dicarboxylate symporter activity GO:0017153 8 8 0,000 6,499E-03 0,0192105 ! axon guidance receptor activity GO:0008046 8 8 0,000 6,499E-03 0,01919461 ! protein targeting to vacuole GO:0006623 8 8 0,000 6,499E-03 0,01917875 ! response to tropane GO:0014073 10 8 0,000 6,499E-03 0,01916291 GO:0042220|response to cocaine, ! purine nucleoside triphosphate catabolic process GO:0009146 8 8 0,000 6,499E-03 0,0191471 ! melanosome localization GO:0032400 8 8 0,000 6,499E-03 0,01913131 ! response to amine stimulus GO:0014075 10 8 0,000 6,499E-03 0,01911555 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 8 8 0,000 6,499E-03 0,01909982 ! sphingomyelin metabolic process GO:0006684 9 8 0,000 6,499E-03 0,01908411 ! regulation of mitochondrial membrane potential GO:0051881 8 8 0,000 6,499E-03 0,01906843 ! synaptic vesicle endocytosis GO:0048488 8 8 0,000 6,499E-03 0,01905278 ! holo TFIIH complex GO:0005675 8 8 0,000 6,499E-03 0,01903715 ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 6,499E-03 0,01902154 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 8 0,000 6,499E-03 0,01900596 ! negative regulation of cytokine secretion GO:0050710 8 8 0,000 6,499E-03 0,01899041 ! regulation of myoblast differentiation GO:0045661 8 8 0,000 6,499E-03 0,01897488 ! vitamin transporter activity GO:0051183 8 8 0,000 6,499E-03 0,01895938 ! positive regulation of erythrocyte differentiation GO:0045648 8 8 0,000 6,499E-03 0,0189439 ! neuromuscular process controlling posture GO:0050884 8 8 0,000 6,499E-03 0,01892845 ! heparan sulfate sulfotransferase activity GO:0034483 8 8 0,000 6,499E-03 0,01891303 ! regulation of epidermal cell differentiation GO:0045604 8 8 0,000 6,499E-03 0,01889762 ! regulation of T-helper 2 cell differentiation GO:0045628 8 8 0,000 6,499E-03 0,01888225 ! positive regulation of T-helper cell differentiation GO:0045624 8 8 0,000 6,499E-03 0,0188669 ! branched chain family amino acid catabolic process GO:0009083 8 8 0,000 6,499E-03 0,01885157 ! regulation of synaptogenesis GO:0051963 8 8 0,000 6,499E-03 0,01883627 ! oocyte differentiation GO:0009994 8 8 0,000 6,499E-03 0,01882099 GO:0048599|oocyte development, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 8 8 0,000 6,499E-03 0,01880574 GO:0003756|protein disulfide isomerase activity, ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 6,499E-03 0,01879051 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 8 0,000 6,499E-03 0,01877531 ! beta-1,3-galactosyltransferase activity GO:0048531 8 8 0,000 6,499E-03 0,01876013 ! establishment of pigment granule localization GO:0051905 8 8 0,000 6,499E-03 0,01874498 ! regulation of telomere maintenance GO:0032204 8 8 0,000 6,499E-03 0,01872985 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 6,499E-03 0,01871474 ! amino sugar catabolic process GO:0046348 8 8 0,000 6,499E-03 0,01869966 GO:0006043|glucosamine catabolic process, ! regulation of amino acid transport GO:0051955 8 8 0,000 6,499E-03 0,01868461 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 6,499E-03 0,01866958 ! T cell receptor signaling pathway GO:0050852 13 8 0,000 6,499E-03 0,01865457 ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 8 0,000 6,499E-03 0,01863958 ! cholesterol transporter activity GO:0017127 8 8 0,000 6,499E-03 0,01862463 ! GABA receptor binding GO:0050811 8 8 0,000 6,499E-03 0,01860969 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 8 8 0,000 6,499E-03 0,01859478 ! regulation of microtubule polymerization GO:0031113 8 8 0,000 6,499E-03 0,01857989 ! regulation of developmental growth GO:0048638 8 8 0,000 6,499E-03 0,01856503 ! GMP binding GO:0019002 10 8 0,000 6,499E-03 0,01855019 GO:0030553|cGMP binding, ! regulation of epithelial cell differentiation GO:0030856 8 8 0,000 6,499E-03 0,01853537 ! negative regulation of cellular catabolic process GO:0031330 9 8 0,000 6,499E-03 0,01852058 ! prostate gland development GO:0030850 8 8 0,000 6,499E-03 0,01850581 ! 7S RNA binding GO:0008312 9 8 0,000 6,499E-03 0,01849106 ! phosphate transport GO:0006817 9 8 0,000 6,499E-03 0,01847634 ! neutral lipid catabolic process GO:0046461 8 8 0,000 6,499E-03 0,01846164 ! protein phosphorylated amino acid binding GO:0045309 10 8 0,000 6,499E-03 0,01844697 ! reproductive behavior GO:0019098 8 8 0,000 6,499E-03 0,01843231 ! cell volume homeostasis GO:0006884 9 8 0,000 6,499E-03 0,01841768 ! regulation of long-term neuronal synaptic plasticity GO:0048169 8 8 0,000 6,499E-03 0,01840308 ! oligopeptide transport GO:0006857 8 8 0,000 6,499E-03 0,0183885 GO:0015198|oligopeptide transporter activity, ! induction of positive chemotaxis GO:0050930 8 8 0,000 6,499E-03 0,01837394 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 6,499E-03 0,0183594 ! regulation of dopamine metabolic process GO:0042053 8 8 0,000 6,499E-03 0,01834489 GO:0042069|regulation of catecholamine metabolic process, ! regulation of carbohydrate biosynthetic process GO:0043255 8 8 0,000 6,499E-03 0,0183304 ! titin binding GO:0031432 8 8 0,000 6,499E-03 0,01831593 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 6,499E-03 0,01830149 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 8 0,000 6,499E-03 0,01828706 ! bone resorption GO:0045453 8 8 0,000 6,499E-03 0,01827266 ! glycerolipid catabolic process GO:0046503 8 8 0,000 6,499E-03 0,01825829 ! endoderm development GO:0007492 8 8 0,000 6,499E-03 0,01824393 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 6,499E-03 0,0182296 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 6,499E-03 0,01821529 ! astrocyte differentiation GO:0048708 8 8 0,000 6,499E-03 0,01820101 ! embryonic cranial skeleton morphogenesis GO:0048701 8 8 0,000 6,499E-03 0,01818674 ! syncytium formation GO:0006949 8 8 0,000 6,499E-03 0,0181725 ! B cell proliferation GO:0042100 8 8 0,000 6,499E-03 0,01815828 ! mannose metabolic process GO:0006013 10 8 0,000 6,499E-03 0,01814408 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 8 8 0,000 6,499E-03 0,01812991 ! asymmetric protein localization GO:0008105 8 8 0,000 6,499E-03 0,01811576 ! tumor necrosis factor binding GO:0043120 8 8 0,000 6,499E-03 0,01810162 ! synaptic transmission, glutamatergic GO:0035249 9 8 0,000 6,499E-03 0,01808752 ! neuron apoptosis GO:0051402 8 8 0,000 6,499E-03 0,01807343 ! macroautophagy GO:0016236 9 8 0,000 6,499E-03 0,01805936 ! Cajal body GO:0015030 8 8 0,000 6,499E-03 0,01804532 ! O-methyltransferase activity GO:0008171 9 8 0,000 6,499E-03 0,0180313 ! H4/H2A histone acetyltransferase complex GO:0043189 9 8 0,000 6,499E-03 0,0180173 ! PcG protein complex GO:0031519 8 8 0,000 6,499E-03 0,01800332 ! ferric iron binding GO:0008199 9 8 0,000 6,499E-03 0,01798937 ! spindle checkpoint GO:0031577 8 8 0,000 6,499E-03 0,01797543 ! G1 DNA damage checkpoint GO:0031571 8 8 0,000 6,499E-03 0,01796152 ! segment specification GO:0007379 8 8 0,000 6,499E-03 0,01794763 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 6,499E-03 0,01793376 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 6,499E-03 0,01791991 ! cellular extravasation GO:0045123 9 8 0,000 6,499E-03 0,01790608 ! pronucleus GO:0045120 8 8 0,000 6,499E-03 0,01789228 ! regulation of insulin receptor signaling pathway GO:0046626 8 8 0,000 6,499E-03 0,01787849 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 8 8 0,000 6,499E-03 0,01786473 ! Rac GTPase activator activity GO:0030675 9 8 0,000 6,499E-03 0,01785099 ! regulation of DNA repair GO:0006282 8 8 0,000 6,499E-03 0,01783727 ! transcription-coupled nucleotide-excision repair GO:0006283 9 8 0,000 6,499E-03 0,01782357 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 6,499E-03 0,01780989 ! antigen processing and presentation of exogenous antigen GO:0019884 9 8 0,000 6,499E-03 0,01779623 ! DNA ligation GO:0006266 8 8 0,000 6,499E-03 0,01778259 ! regulation of T cell differentiation in the thymus GO:0033081 8 8 0,000 6,499E-03 0,01776898 ! negative regulation of systemic arterial blood pressure GO:0003085 8 8 0,000 6,499E-03 0,01775538 ! multicellular organismal aging GO:0010259 8 8 0,000 6,499E-03 0,01774181 ! erythrocyte development GO:0048821 8 8 0,000 6,499E-03 0,01772825 ! interleukin-1 receptor activity GO:0004908 8 8 0,000 6,499E-03 0,01771472 ! positive regulation of monooxygenase activity GO:0032770 8 8 0,000 6,499E-03 0,01770121 ! protein import into peroxisome matrix GO:0016558 8 8 0,000 6,499E-03 0,01768772 ! gamma-tubulin binding GO:0043015 8 8 0,000 6,499E-03 0,01767424 ! ribosome binding GO:0043022 9 8 0,000 6,499E-03 0,01766079 ! NADPH oxidase complex GO:0043020 8 8 0,000 6,499E-03 0,01764736 ! mRNA polyadenylation GO:0006378 8 8 0,000 6,499E-03 0,01763395 ! sodium:amino acid symporter activity GO:0005283 8 8 0,000 6,499E-03 0,01762056 ! adenylyltransferase activity GO:0070566 8 8 0,000 6,499E-03 0,0176072 ! zymogen activation GO:0031638 8 8 0,000 6,499E-03 0,01759385 ! axonal fasciculation GO:0007413 8 8 0,000 6,499E-03 0,01758052 ! T cell homeostasis GO:0043029 9 8 0,000 6,499E-03 0,01756721 ! negative regulation of nuclear division GO:0051784 8 8 0,000 6,499E-03 0,01755392 GO:0045839|negative regulation of mitosis, ! caspase inhibitor activity GO:0043027 8 8 0,000 6,499E-03 0,01754065 ! energy coupled proton transport, against electrochemical gradient GO:0015988 8 8 0,000 6,499E-03 0,0175274 GO:0015991|ATP hydrolysis coupled proton transport, ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 8 8 0,000 6,499E-03 0,01751418 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 6,499E-03 0,01750097 ! thyroid hormone receptor activity GO:0004887 8 8 0,000 6,499E-03 0,01748778 ! wide pore channel activity GO:0022829 8 8 0,000 6,499E-03 0,01747461 ! ligand-regulated transcription factor activity GO:0003706 8 8 0,000 6,499E-03 0,01746146 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 6,499E-03 0,01744833 ! hormone catabolic process GO:0042447 8 8 0,000 6,499E-03 0,01743522 ! positive regulation of ATPase activity GO:0032781 8 8 0,000 6,499E-03 0,01742213 ! biogenic amine catabolic process GO:0042402 11 8 0,000 6,499E-03 0,01740906 ! Notch binding GO:0005112 8 8 0,000 6,499E-03 0,01739601 ! death receptor binding GO:0005123 8 8 0,000 6,499E-03 0,01738298 ! ATPase regulator activity GO:0060590 8 8 0,000 6,499E-03 0,01736997 ! pyrimidine base metabolic process GO:0006206 10 8 0,000 6,499E-03 0,01735698 ! epidermal growth factor receptor binding GO:0005154 9 8 0,000 6,499E-03 0,01734401 ! dihydropyridine-sensitive calcium channel activity GO:0015270 8 8 0,000 6,499E-03 0,01733106 ! calcium-release channel activity GO:0015278 8 8 0,000 6,499E-03 0,01731812 ! tubulin-tyrosine ligase activity GO:0004835 8 8 0,000 6,499E-03 0,01730521 ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 6,499E-03 0,01729231 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 8 8 0,000 6,499E-03 0,01727944 ! nucleus localization GO:0051647 10 8 0,000 6,499E-03 0,01726658 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 6,499E-03 0,01725374 ! negative regulation of immune effector process GO:0002698 12 8 0,000 6,499E-03 0,01724092 ! C-X-C chemokine receptor activity GO:0016494 8 8 0,000 6,499E-03 0,01722812 ! adenosine deaminase activity GO:0004000 8 8 0,000 6,499E-03 0,01721534 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9 9 0,000 7,308E-03 0,01934568 ! respiratory burst GO:0045730 9 9 0,000 7,308E-03 0,01933135 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 9 9 0,000 7,308E-03 0,01931705 ! telencephalon cell migration GO:0022029 9 9 0,000 7,308E-03 0,01930276 ! 'de novo' posttranslational protein folding GO:0051084 9 9 0,000 7,308E-03 0,01928849 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 7,308E-03 0,01927425 ! cGMP metabolic process GO:0046068 9 9 0,000 7,308E-03 0,01926002 GO:0006182|cGMP biosynthetic process, ! regulation of epidermal growth factor receptor activity GO:0007176 9 9 0,000 7,308E-03 0,01924582 GO:0010469|regulation of receptor activity, ! inositol trisphosphate phosphatase activity GO:0046030 11 9 0,000 7,308E-03 0,01923163 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! axon part GO:0033267 12 9 0,000 7,308E-03 0,01921747 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9 9 0,000 7,308E-03 0,01920333 ! RNA polyadenylation GO:0043631 9 9 0,000 7,308E-03 0,01918921 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 9 0,000 7,308E-03 0,01917511 ! regulation of receptor-mediated endocytosis GO:0048259 9 9 0,000 7,308E-03 0,01916103 ! artery development GO:0060840 9 9 0,000 7,308E-03 0,01914698 GO:0048844|artery morphogenesis, ! photoreceptor cell development GO:0042461 12 9 0,000 7,308E-03 0,01913294 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 9 9 0,000 7,308E-03 0,01911892 ! middle ear morphogenesis GO:0042474 9 9 0,000 7,308E-03 0,01910493 ! regulation of mesenchymal cell proliferation GO:0010464 9 9 0,000 7,308E-03 0,01909095 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 12 9 0,000 7,308E-03 0,01907699 GO:0046330|positive regulation of JNK cascade, ! positive regulation of heart contraction GO:0045823 10 9 0,000 7,308E-03 0,01906306 ! lung alveolus development GO:0048286 9 9 0,000 7,308E-03 0,01904914 ! ciliary or flagellar motility GO:0001539 9 9 0,000 7,308E-03 0,01903525 ! beta-amyloid binding GO:0001540 10 9 0,000 7,308E-03 0,01902138 ! pathogenesis GO:0009405 9 9 0,000 7,308E-03 0,01900752 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 10 9 0,000 7,308E-03 0,01899369 ! regulated secretory pathway GO:0045055 9 9 0,000 7,308E-03 0,01897987 ! regulation of S phase of mitotic cell cycle GO:0007090 9 9 0,000 7,308E-03 0,01896608 ! estrogen receptor binding GO:0030331 9 9 0,000 7,308E-03 0,01895231 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 10 9 0,000 7,308E-03 0,01893855 ! regulation of defense response to virus by virus GO:0050690 9 9 0,000 7,308E-03 0,01892482 ! histidine metabolic process GO:0006547 9 9 0,000 7,308E-03 0,01891111 GO:0009075|histidine family amino acid metabolic process, ! L-phenylalanine metabolic process GO:0006558 10 9 0,000 7,308E-03 0,01889741 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 9 9 0,000 7,308E-03 0,01888374 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 9 9 0,000 7,308E-03 0,01887009 ! nucleobase biosynthetic process GO:0046112 11 9 0,000 7,308E-03 0,01885645 ! regulation of Cdc42 protein signal transduction GO:0032489 9 9 0,000 7,308E-03 0,01884284 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of calcium ion transport into cytosol GO:0010522 12 9 0,000 7,308E-03 0,01882924 ! entry into host cell GO:0030260 9 9 0,000 7,308E-03 0,01881567 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 9 9 0,000 7,308E-03 0,01880211 ! regulation of lipoprotein lipase activity GO:0051004 9 9 0,000 7,308E-03 0,01878857 ! retinoic acid metabolic process GO:0042573 9 9 0,000 7,308E-03 0,01877506 ! retinol metabolic process GO:0042572 9 9 0,000 7,308E-03 0,01876156 ! behavioral fear response GO:0001662 9 9 0,000 7,308E-03 0,01874808 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 10 9 0,000 7,308E-03 0,01873462 ! regulation of vascular endothelial growth factor production GO:0010574 9 9 0,000 7,308E-03 0,01872118 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9 9 0,000 7,308E-03 0,01870776 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! motor axon guidance GO:0008045 9 9 0,000 7,308E-03 0,01869436 ! regulation of gliogenesis GO:0014013 9 9 0,000 7,308E-03 0,01868098 GO:0045685|regulation of glial cell differentiation, ! recycling endosome membrane GO:0055038 10 9 0,000 7,308E-03 0,01866762 ! pigment granule localization GO:0051875 9 9 0,000 7,308E-03 0,01865427 ! glycosphingolipid biosynthetic process GO:0006688 9 9 0,000 7,308E-03 0,01864095 ! nucleoside diphosphate metabolic process GO:0009132 10 9 0,000 7,308E-03 0,01862764 ! phosphoinositide 3-kinase cascade GO:0014065 9 9 0,000 7,308E-03 0,01861436 ! cell wall macromolecule catabolic process GO:0016998 10 9 0,000 7,308E-03 0,01860109 ! purine ribonucleotide catabolic process GO:0009154 9 9 0,000 7,308E-03 0,01858784 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 9 9 0,000 7,308E-03 0,01857461 ! nitric oxide metabolic process GO:0046209 9 9 0,000 7,308E-03 0,0185614 GO:0006809|nitric oxide biosynthetic process, ! mismatch repair complex GO:0032300 9 9 0,000 7,308E-03 0,01854821 ! icosanoid secretion GO:0032309 9 9 0,000 7,308E-03 0,01853503 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 10 9 0,000 7,308E-03 0,01852188 GO:0010092|specification of organ identity, ! retinal ganglion cell axon guidance GO:0031290 9 9 0,000 7,308E-03 0,01850874 ! morphogenesis of a polarized epithelium GO:0001738 9 9 0,000 7,308E-03 0,01849563 ! sterol catabolic process GO:0016127 9 9 0,000 7,308E-03 0,01848253 GO:0006707|cholesterol catabolic process, ! prophase GO:0051324 9 9 0,000 7,308E-03 0,01846945 ! peptidyl-lysine modification GO:0018205 9 9 0,000 7,308E-03 0,01845638 ! pancreatic ribonuclease activity GO:0004522 9 9 0,000 7,308E-03 0,01844334 ! clathrin coat of coated pit GO:0030132 12 9 0,000 7,308E-03 0,01843032 ! SNARE complex GO:0031201 10 9 0,000 7,308E-03 0,01841731 ! ubiquinone metabolic process GO:0006743 10 9 0,000 7,308E-03 0,01840432 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! snRNA binding GO:0017069 9 9 0,000 7,308E-03 0,01839135 ! regulation of macrophage differentiation GO:0045649 9 9 0,000 7,308E-03 0,0183784 ! regulation of osteoclast differentiation GO:0045670 10 9 0,000 7,308E-03 0,01836547 ! positive regulation of neuron differentiation GO:0045666 9 9 0,000 7,308E-03 0,01835255 ! negative regulation of lymphocyte differentiation GO:0045620 9 9 0,000 7,308E-03 0,01833965 ! methionine biosynthetic process GO:0009086 10 9 0,000 7,308E-03 0,01832678 ! peptidoglycan binding GO:0042834 9 9 0,000 7,308E-03 0,01831391 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 7,308E-03 0,01830107 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! pyridine nucleotide biosynthetic process GO:0019363 9 9 0,000 7,308E-03 0,01828825 ! intramolecular transferase activity, phosphotransferases GO:0016868 9 9 0,000 7,308E-03 0,01827544 ! cholesterol efflux GO:0033344 9 9 0,000 7,308E-03 0,01826265 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 9 9 0,000 7,308E-03 0,01824988 ! metalloenzyme inhibitor activity GO:0048551 10 9 0,000 7,308E-03 0,01823713 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! leukocyte mediated cytotoxicity GO:0001909 9 9 0,000 7,308E-03 0,01822439 ! anterior/posterior axis specification GO:0009948 9 9 0,000 7,308E-03 0,01821167 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 7,308E-03 0,01819897 ! detection of calcium ion GO:0005513 10 9 0,000 7,308E-03 0,01818629 ! negative regulation of glucose import GO:0046325 9 9 0,000 7,308E-03 0,01817363 GO:0010829|negative regulation of glucose transport, ! regulation of fibrinolysis GO:0051917 9 9 0,000 7,308E-03 0,01816098 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 9 0,000 7,308E-03 0,01814835 ! hydrolase activity, acting on ether bonds GO:0016801 9 9 0,000 7,308E-03 0,01813574 ! desmosome GO:0030057 9 9 0,000 7,308E-03 0,01812314 ! prepulse inhibition GO:0060134 9 9 0,000 7,308E-03 0,01811057 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 9 0,000 7,308E-03 0,01809801 ! negative regulation of B cell activation GO:0050869 9 9 0,000 7,308E-03 0,01808547 ! anchoring collagen GO:0030934 9 9 0,000 7,308E-03 0,01807294 ! axon extension GO:0048675 10 9 0,000 7,308E-03 0,01806043 ! neuron fate specification GO:0048665 9 9 0,000 7,308E-03 0,01804794 ! positive regulation of glucose metabolic process GO:0010907 9 9 0,000 7,308E-03 0,01803547 ! cortical actin cytoskeleton organization GO:0030866 9 9 0,000 7,308E-03 0,01802302 ! virus-host interaction GO:0019048 13 9 0,000 7,308E-03 0,01801058 ! rough endoplasmic reticulum membrane GO:0030867 9 9 0,000 7,308E-03 0,01799816 ! pentose-phosphate shunt GO:0006098 9 9 0,000 7,308E-03 0,01798575 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 7,308E-03 0,01797337 ! DNA bending activity GO:0008301 9 9 0,000 7,308E-03 0,017961 ! social behavior GO:0035176 9 9 0,000 7,308E-03 0,01794864 ! secondary active sulfate transmembrane transporter activity GO:0008271 9 9 0,000 7,308E-03 0,01793631 ! dipeptidyl-peptidase activity GO:0008239 11 9 0,000 7,308E-03 0,01792399 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 7,308E-03 0,01791169 ! very-low-density lipoprotein particle GO:0034361 9 9 0,000 7,308E-03 0,0178994 GO:0034385|triglyceride-rich lipoprotein particle, ! high-density lipoprotein particle GO:0034364 9 9 0,000 7,308E-03 0,01788713 ! amyloid precursor protein metabolic process GO:0042982 10 9 0,000 7,308E-03 0,01787488 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 11 9 0,000 7,308E-03 0,01786265 ! blood vessel remodeling GO:0001974 10 9 0,000 7,308E-03 0,01785043 ! C-X-C chemokine binding GO:0019958 9 9 0,000 7,308E-03 0,01783823 ! 3'-5'-exoribonuclease activity GO:0000175 9 9 0,000 7,308E-03 0,01782604 ! exosome (RNase complex) GO:0000178 9 9 0,000 7,308E-03 0,01781388 ! inositol phosphate-mediated signaling GO:0048016 9 9 0,000 7,308E-03 0,01780172 ! DNA N-glycosylase activity GO:0019104 9 9 0,000 7,308E-03 0,01778959 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 9 9 0,000 7,308E-03 0,01777747 GO:0033549|MAP kinase phosphatase activity, ! ER overload response GO:0006983 11 9 0,000 7,308E-03 0,01776537 ! zinc ion transmembrane transporter activity GO:0005385 9 9 0,000 7,308E-03 0,01775328 ! glucose transmembrane transporter activity GO:0005355 9 9 0,000 7,308E-03 0,01774122 ! retrograde transport, endosome to Golgi GO:0042147 10 9 0,000 7,308E-03 0,01772916 ! phagocytosis, engulfment GO:0006911 10 9 0,000 7,308E-03 0,01771713 ! neurotransmitter biosynthetic process GO:0042136 10 9 0,000 7,308E-03 0,01770511 ! carbohydrate phosphatase activity GO:0019203 9 9 0,000 7,308E-03 0,0176931 ! glutathione peroxidase activity GO:0004602 9 9 0,000 7,308E-03 0,01768112 ! acyl-CoA thioesterase activity GO:0016291 9 9 0,000 7,308E-03 0,01766915 ! lysophospholipase activity GO:0004622 9 9 0,000 7,308E-03 0,01765719 ! brain morphogenesis GO:0048854 9 9 0,000 7,308E-03 0,01764525 ! apolipoprotein binding GO:0034185 9 9 0,000 7,308E-03 0,01763333 ! synaptic vesicle membrane GO:0030672 9 9 0,000 7,308E-03 0,01762142 ! RNA-dependent DNA replication GO:0006278 9 9 0,000 7,308E-03 0,01760953 ! positive regulation of systemic arterial blood pressure GO:0003084 10 9 0,000 7,308E-03 0,01759766 ! kinesin binding GO:0019894 9 9 0,000 7,308E-03 0,0175858 ! nucleoside bisphosphate metabolic process GO:0033865 10 9 0,000 7,308E-03 0,01757396 ! renal water homeostasis GO:0003091 9 9 0,000 7,308E-03 0,01756213 ! positive regulation of interleukin-6 production GO:0032755 9 9 0,000 7,308E-03 0,01755032 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 7,308E-03 0,01753853 ! histone methylation GO:0016571 10 9 0,000 7,308E-03 0,01752675 ! mRNA cleavage GO:0006379 9 9 0,000 7,308E-03 0,01751499 ! negative regulation of tumor necrosis factor production GO:0032720 9 9 0,000 7,308E-03 0,01750324 ! regulation of transcription from RNA polymerase III promoter GO:0006359 9 9 0,000 7,308E-03 0,01749151 ! sarcoplasmic reticulum membrane GO:0033017 10 9 0,000 7,308E-03 0,01747979 ! opioid receptor activity GO:0004985 9 9 0,000 7,308E-03 0,01746809 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 7,308E-03 0,01745641 ! salivary gland development GO:0007431 10 9 0,000 7,308E-03 0,01744474 ! glucosidase activity GO:0015926 10 9 0,000 7,308E-03 0,01743308 ! adrenoceptor activity GO:0004935 11 9 0,000 7,308E-03 0,01742145 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 9 9 0,000 7,308E-03 0,01740983 ! positive regulation of leukocyte migration GO:0002687 9 9 0,000 7,308E-03 0,01739822 ! purine base metabolic process GO:0006144 11 9 0,000 7,308E-03 0,01738663 ! mRNA 3'-UTR binding GO:0003730 9 9 0,000 7,308E-03 0,01737505 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 9 9 0,000 7,308E-03 0,01736349 ! receptor inhibitor activity GO:0030547 9 9 0,000 7,308E-03 0,01735195 GO:0048019|receptor antagonist activity, ! negative regulation of BMP signaling pathway GO:0030514 9 9 0,000 7,308E-03 0,01734042 ! ionotropic glutamate receptor complex GO:0008328 11 9 0,000 7,308E-03 0,0173289 ! transforming growth factor beta receptor binding GO:0005160 9 9 0,000 7,308E-03 0,0173174 ! palmitoyltransferase activity GO:0016409 9 9 0,000 7,308E-03 0,01730592 ! arylsulfatase activity GO:0004065 9 9 0,000 7,308E-03 0,01729445 ! phospholipase inhibitor activity GO:0004859 9 9 0,000 7,308E-03 0,017283 ! behavioral response to nicotine GO:0035095 9 9 0,000 7,308E-03 0,01727156 ! adenylate kinase activity GO:0004017 10 9 0,000 7,308E-03 0,01726014 ! alcohol dehydrogenase (NAD) activity GO:0004022 9 9 0,000 7,308E-03 0,01724873 ! mitochondrion localization GO:0051646 9 9 0,000 7,308E-03 0,01723734 ! localization within membrane GO:0051668 9 9 0,000 7,308E-03 0,01722596 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 10 0,000 8,117E-03 0,01912019 ! lipid particle GO:0005811 10 10 0,000 8,117E-03 0,01910759 ! myotube differentiation GO:0014902 10 10 0,000 8,117E-03 0,019095 ! generation of neurons in the forebrain GO:0021872 11 10 0,000 8,117E-03 0,01908243 ! regulation of cellular amine metabolic process GO:0033238 10 10 0,000 8,117E-03 0,01906988 ! synapsis GO:0007129 10 10 0,000 8,117E-03 0,01905734 GO:0070192|chromosome organization involved in meiosis, ! filopodium assembly GO:0046847 12 10 0,000 8,117E-03 0,01904482 ! UTP metabolic process GO:0046051 10 10 0,000 8,117E-03 0,01903231 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 10 10 0,000 8,117E-03 0,01901982 ! COPI coating of Golgi vesicle GO:0048205 10 10 0,000 8,117E-03 0,01900735 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 10 10 0,000 8,117E-03 0,0189949 ! platelet alpha granule membrane GO:0031092 11 10 0,000 8,117E-03 0,01898246 ! macromolecule transmembrane transporter activity GO:0022884 10 10 0,000 8,117E-03 0,01897003 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! lipoprotein receptor binding GO:0070325 10 10 0,000 8,117E-03 0,01895763 GO:0050750|low-density lipoprotein receptor binding, ! thyroid hormone receptor coactivator activity GO:0030375 10 10 0,000 8,117E-03 0,01894524 GO:0010861|thyroid hormone receptor activator activity, ! auditory receptor cell differentiation GO:0042491 11 10 0,000 8,117E-03 0,01893286 ! regulation of chemokine biosynthetic process GO:0045073 10 10 0,000 8,117E-03 0,0189205 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 10 10 0,000 8,117E-03 0,01890816 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 8,117E-03 0,01889584 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 10 0,000 8,117E-03 0,01888353 ! nucleotide-sugar metabolic process GO:0009225 11 10 0,000 8,117E-03 0,01887123 ! regulation of catecholamine secretion GO:0050433 10 10 0,000 8,117E-03 0,01885895 ! melanocyte differentiation GO:0030318 10 10 0,000 8,117E-03 0,01884669 GO:0050931|pigment cell differentiation, ! ER-Golgi intermediate compartment membrane GO:0033116 10 10 0,000 8,117E-03 0,01883445 ! deoxyribonucleotide catabolic process GO:0009264 10 10 0,000 8,117E-03 0,01882222 ! L-serine metabolic process GO:0006563 11 10 0,000 8,117E-03 0,01881 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 10 10 0,000 8,117E-03 0,0187978 ! lipase inhibitor activity GO:0055102 10 10 0,000 8,117E-03 0,01878562 ! autophagic vacuole GO:0005776 11 10 0,000 8,117E-03 0,01877345 ! NAD metabolic process GO:0019674 10 10 0,000 8,117E-03 0,0187613 ! stereocilium GO:0032420 10 10 0,000 8,117E-03 0,01874917 GO:0032421|stereocilium bundle, ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 8,117E-03 0,01873705 ! regulation of sodium ion transport GO:0002028 10 10 0,000 8,117E-03 0,01872494 ! forebrain cell migration GO:0021885 10 10 0,000 8,117E-03 0,01871286 ! organelle subcompartment GO:0031984 11 10 0,000 8,117E-03 0,01870078 ! chondrocyte differentiation GO:0002062 10 10 0,000 8,117E-03 0,01868873 ! negative regulation of ossification GO:0030279 10 10 0,000 8,117E-03 0,01867668 ! regulation of smoothened signaling pathway GO:0008589 10 10 0,000 8,117E-03 0,01866466 ! heparan sulfate proteoglycan metabolic process GO:0030201 10 10 0,000 8,117E-03 0,01865265 ! phosphatidylcholine biosynthetic process GO:0006656 12 10 0,000 8,117E-03 0,01864065 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 10 10 0,000 8,117E-03 0,01862867 ! protein homotetramerization GO:0051289 11 10 0,000 8,117E-03 0,01861671 ! oligodendrocyte development GO:0014003 10 10 0,000 8,117E-03 0,01860476 ! positive regulation of phagocytosis GO:0050766 10 10 0,000 8,117E-03 0,01859282 ! response to dsRNA GO:0043331 10 10 0,000 8,117E-03 0,01858091 ! snRNA metabolic process GO:0016073 10 10 0,000 8,117E-03 0,018569 GO:0016180|snRNA processing, ! cranial nerve development GO:0021545 10 10 0,000 8,117E-03 0,01855711 ! fucose catabolic process GO:0019317 11 10 0,000 8,117E-03 0,01854524 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 10 10 0,000 8,117E-03 0,01853338 ! retinal binding GO:0016918 10 10 0,000 8,117E-03 0,01852154 ! leukocyte activation during immune response GO:0002366 10 10 0,000 8,117E-03 0,01850971 GO:0002263|cell activation during immune response, ! cerebellum morphogenesis GO:0021587 11 10 0,000 8,117E-03 0,0184979 GO:0021696|cerebellar cortex morphogenesis, ! photoreceptor outer segment GO:0001750 10 10 0,000 8,117E-03 0,01848611 ! negative regulation of MAPKKK cascade GO:0043409 10 10 0,000 8,117E-03 0,01847432 ! regulation of T-helper 2 type immune response GO:0002828 10 10 0,000 8,117E-03 0,01846256 ! ribonuclease P activity GO:0004526 10 10 0,000 8,117E-03 0,0184508 ! midbrain development GO:0030901 10 10 0,000 8,117E-03 0,01843907 ! musculoskeletal movement GO:0050881 10 10 0,000 8,117E-03 0,01842734 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 10 10 0,000 8,117E-03 0,01841564 ! regulation of T-helper cell differentiation GO:0045622 10 10 0,000 8,117E-03 0,01840394 ! fatty-acid ligase activity GO:0015645 10 10 0,000 8,117E-03 0,01839227 GO:0004467|long-chain-fatty-acid-CoA ligase activity, ! regulation of mRNA stability GO:0043488 10 10 0,000 8,117E-03 0,0183806 ! quaternary ammonium group transport GO:0015697 10 10 0,000 8,117E-03 0,01836896 ! regulation of RNA splicing GO:0043484 10 10 0,000 8,117E-03 0,01835732 ! embryonic gut development GO:0048566 10 10 0,000 8,117E-03 0,0183457 ! positive regulation of amine transport GO:0051954 10 10 0,000 8,117E-03 0,0183341 ! defense response to Gram-positive bacterium GO:0050830 10 10 0,000 8,117E-03 0,01832251 ! mRNA 3'-end processing GO:0031124 10 10 0,000 8,117E-03 0,01831094 ! lysogeny GO:0030069 10 10 0,000 8,117E-03 0,01829938 GO:0019047|provirus integration, ! lamellipodium assembly GO:0030032 11 10 0,000 8,117E-03 0,01828783 ! establishment of cell polarity GO:0030010 10 10 0,000 8,117E-03 0,0182763 ! regulation of synapse organization GO:0050807 10 10 0,000 8,117E-03 0,01826478 ! cell wall macromolecule metabolic process GO:0044036 11 10 0,000 8,117E-03 0,01825328 ! acyl-CoA binding GO:0000062 10 10 0,000 8,117E-03 0,0182418 ! negative regulation of muscle development GO:0048635 11 10 0,000 8,117E-03 0,01823032 GO:0045843|negative regulation of striated muscle development, ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 8,117E-03 0,01821886 ! GDP binding GO:0019003 10 10 0,000 8,117E-03 0,01820742 ! photoreceptor activity GO:0009881 10 10 0,000 8,117E-03 0,01819599 ! somatic diversification of immune receptors via somatic mutation GO:0002566 10 10 0,000 8,117E-03 0,01818458 GO:0016446|somatic hypermutation of immunoglobulin genes, ! cortical cytoskeleton organization GO:0030865 10 10 0,000 8,117E-03 0,01817317 ! nitric-oxide synthase binding GO:0050998 11 10 0,000 8,117E-03 0,01816179 ! nuclear chromosome, telomeric region GO:0000784 10 10 0,000 8,117E-03 0,01815042 ! nucleotidase activity GO:0008252 10 10 0,000 8,117E-03 0,01813906 ! detection of mechanical stimulus GO:0050982 10 10 0,000 8,117E-03 0,01812771 ! protein complex disassembly GO:0043241 11 10 0,000 8,117E-03 0,01811638 GO:0043624|cellular protein complex disassembly, ! androgen metabolic process GO:0008209 10 10 0,000 8,117E-03 0,01810507 ! lateral plasma membrane GO:0016328 10 10 0,000 8,117E-03 0,01809377 ! estrogen metabolic process GO:0008210 10 10 0,000 8,117E-03 0,01808248 ! nucleocytoplasmic transporter activity GO:0005487 10 10 0,000 8,117E-03 0,01807121 ! retinol dehydrogenase activity GO:0004745 10 10 0,000 8,117E-03 0,01805995 ! negative regulation of cell-matrix adhesion GO:0001953 12 10 0,000 8,117E-03 0,0180487 GO:0010812|negative regulation of cell-substrate adhesion, ! interleukin-1 binding GO:0019966 10 10 0,000 8,117E-03 0,01803747 ! endothelial cell differentiation GO:0045446 10 10 0,000 8,117E-03 0,01802625 ! cullin-RING ubiquitin ligase complex GO:0031461 10 10 0,000 8,117E-03 0,01801505 ! acid phosphatase activity GO:0003993 10 10 0,000 8,117E-03 0,01800386 ! sodium:potassium-exchanging ATPase activity GO:0005391 11 10 0,000 8,117E-03 0,01799268 ! calcium-transporting ATPase activity GO:0005388 12 10 0,000 8,117E-03 0,01798152 ! telomeric DNA binding GO:0042162 11 10 0,000 8,117E-03 0,01797037 ! regulation of intracellular pH GO:0051453 10 10 0,000 8,117E-03 0,01795924 ! lipid digestion GO:0044241 10 10 0,000 8,117E-03 0,01794812 ! multicellular organism growth GO:0035264 10 10 0,000 8,117E-03 0,01793701 ! receptor clustering GO:0043113 10 10 0,000 8,117E-03 0,01792592 ! L-glutamate transmembrane transporter activity GO:0005313 10 10 0,000 8,117E-03 0,01791484 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 11 10 0,000 8,117E-03 0,01790378 ! adult heart development GO:0007512 12 10 0,000 8,117E-03 0,01789272 ! actin cytoskeleton reorganization GO:0031532 12 10 0,000 8,117E-03 0,01788169 ! signalosome GO:0008180 10 10 0,000 8,117E-03 0,01787066 ! prefoldin complex GO:0016272 10 10 0,000 8,117E-03 0,01785965 ! neuromuscular junction GO:0031594 10 10 0,000 8,117E-03 0,01784865 ! regulation of bone resorption GO:0045124 11 10 0,000 8,117E-03 0,01783767 ! positive regulation of peptide secretion GO:0002793 10 10 0,000 8,117E-03 0,0178267 ! alpha-beta T cell differentiation GO:0046632 11 10 0,000 8,117E-03 0,01781574 ! negative regulation of myeloid leukocyte differentiation GO:0002762 10 10 0,000 8,117E-03 0,0178048 ! positive regulation of T cell mediated immunity GO:0002711 14 10 0,000 8,117E-03 0,01779387 ! taste receptor activity GO:0008527 10 10 0,000 8,117E-03 0,01778295 ! Ran GTPase binding GO:0008536 10 10 0,000 8,117E-03 0,01777205 ! endocytic vesicle membrane GO:0030666 10 10 0,000 8,117E-03 0,01776116 ! regulation of interleukin-12 production GO:0032655 10 10 0,000 8,117E-03 0,01775028 ! ribosome assembly GO:0042255 10 10 0,000 8,117E-03 0,01773942 ! DNA methylation GO:0006306 12 10 0,000 8,117E-03 0,01772857 GO:0006305|DNA alkylation, ! protein-hormone receptor activity GO:0016500 10 10 0,000 8,117E-03 0,01771773 ! bile acid transmembrane transporter activity GO:0015125 10 10 0,000 8,117E-03 0,01770691 ! proteasome accessory complex GO:0022624 11 10 0,000 8,117E-03 0,0176961 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 13 10 0,000 8,117E-03 0,0176853 ! prostaglandin receptor activity GO:0004955 11 10 0,000 8,117E-03 0,01767452 ! regulation of isotype switching GO:0045191 14 10 0,000 8,117E-03 0,01766375 ! peptide transporter activity GO:0015197 10 10 0,000 8,117E-03 0,01765299 ! regulation of leukocyte migration GO:0002685 10 10 0,000 8,117E-03 0,01764225 ! retinoid-X receptor activity GO:0004886 10 10 0,000 8,117E-03 0,01763152 ! GTPase inhibitor activity GO:0005095 10 10 0,000 8,117E-03 0,0176208 ! pattern recognition receptor activity GO:0008329 10 10 0,000 8,117E-03 0,01761009 ! gamma-tubulin complex GO:0000930 12 10 0,000 8,117E-03 0,0175994 ! germ cell migration GO:0008354 10 10 0,000 8,117E-03 0,01758872 ! regulation of organic acid transport GO:0032890 10 10 0,000 8,117E-03 0,01757806 ! negative regulation of mast cell proliferation GO:0070667 10 10 0,000 8,117E-03 0,0175674 GO:0042130|negative regulation of T cell proliferation, ! cardiac cell differentiation GO:0035051 11 10 0,000 8,117E-03 0,01755676 ! amiloride-sensitive sodium channel activity GO:0015280 10 10 0,000 8,117E-03 0,01754613 ! sterol transporter activity GO:0015248 10 10 0,000 8,117E-03 0,01753552 ! regulation of embryonic development GO:0045995 11 10 0,000 8,117E-03 0,01752492 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 11 11 0,000 8,925E-03 0,01925857 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 11 0,000 8,925E-03 0,01924694 ! negative regulation of blood pressure GO:0045776 11 11 0,000 8,925E-03 0,01923533 ! RNA cap binding GO:0000339 12 11 0,000 8,925E-03 0,01922373 ! CTP metabolic process GO:0046036 12 11 0,000 8,925E-03 0,01921214 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 11 0,000 8,925E-03 0,01920057 ! response to pain GO:0048265 11 11 0,000 8,925E-03 0,01918901 ! axonemal dynein complex GO:0005858 11 11 0,000 8,925E-03 0,01917746 ! eukaryotic translation initiation factor 3 complex GO:0005852 11 11 0,000 8,925E-03 0,01916593 ! dopamine receptor signaling pathway GO:0007212 13 11 0,000 8,925E-03 0,01915441 ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 11 0,000 8,925E-03 0,01914291 ! endocrine pancreas development GO:0031018 11 11 0,000 8,925E-03 0,01913142 ! regulation of interferon-gamma biosynthetic process GO:0045072 12 11 0,000 8,925E-03 0,01911994 ! regulation of exit from mitosis GO:0007096 11 11 0,000 8,925E-03 0,01910848 ! chylomicron GO:0042627 11 11 0,000 8,925E-03 0,01909703 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 11 11 0,000 8,925E-03 0,01908559 ! glycolipid biosynthetic process GO:0009247 11 11 0,000 8,925E-03 0,01907417 ! transforming growth factor beta binding GO:0050431 11 11 0,000 8,925E-03 0,01906276 ! glutamate metabolic process GO:0006536 12 11 0,000 8,925E-03 0,01905137 ! ribonucleotide catabolic process GO:0009261 11 11 0,000 8,925E-03 0,01903999 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 8,925E-03 0,01902862 ! vascular endothelial growth factor receptor activity GO:0005021 11 11 0,000 8,925E-03 0,01901727 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 11 11 0,000 8,925E-03 0,01900593 GO:0045125|bioactive lipid receptor activity, ! Rac GTPase binding GO:0048365 11 11 0,000 8,925E-03 0,0189946 ! epithelial cell development GO:0002064 11 11 0,000 8,925E-03 0,01898329 ! filamentous actin GO:0031941 11 11 0,000 8,925E-03 0,01897199 ! temperature homeostasis GO:0001659 11 11 0,000 8,925E-03 0,0189607 ! structural constituent of epidermis GO:0030280 13 11 0,000 8,925E-03 0,01894943 ! protein targeting to peroxisome GO:0006625 11 11 0,000 8,925E-03 0,01893817 ! spectrin GO:0008091 11 11 0,000 8,925E-03 0,01892692 ! cytoskeletal adaptor activity GO:0008093 14 11 0,000 8,925E-03 0,01891569 ! negative regulation of axonogenesis GO:0050771 13 11 0,000 8,925E-03 0,01890447 ! regulation of phagocytosis GO:0050764 11 11 0,000 8,925E-03 0,01889327 ! nucleoside triphosphate catabolic process GO:0009143 11 11 0,000 8,925E-03 0,01888207 ! synaptic vesicle exocytosis GO:0016079 12 11 0,000 8,925E-03 0,01887089 ! regulation of B cell differentiation GO:0045577 15 11 0,000 8,925E-03 0,01885973 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 11 11 0,000 8,925E-03 0,01884857 ! basal lamina GO:0005605 12 11 0,000 8,925E-03 0,01883743 ! gastrulation with mouth forming second GO:0001702 12 11 0,000 8,925E-03 0,01882631 ! spinal cord motor neuron differentiation GO:0021522 11 11 0,000 8,925E-03 0,01881519 ! hindbrain morphogenesis GO:0021575 13 11 0,000 8,925E-03 0,01880409 ! regulation of hormone metabolic process GO:0032350 12 11 0,000 8,925E-03 0,01879301 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 11 0,000 8,925E-03 0,01878193 GO:0050706|regulation of interleukin-1 beta secretion, ! COPI vesicle coat GO:0030126 11 11 0,000 8,925E-03 0,01877087 GO:0030663|COPI coated vesicle membrane, ! clathrin coat of trans-Golgi network vesicle GO:0030130 14 11 0,000 8,925E-03 0,01875982 ! tRNA-specific ribonuclease activity GO:0004549 11 11 0,000 8,925E-03 0,01874879 ! cofactor transporter activity GO:0051184 11 11 0,000 8,925E-03 0,01873777 ! cobalt ion binding GO:0050897 11 11 0,000 8,925E-03 0,01872676 ! pseudouridine synthase activity GO:0009982 12 11 0,000 8,925E-03 0,01871576 ! aromatic amino acid family catabolic process GO:0009074 12 11 0,000 8,925E-03 0,01870478 ! serine family amino acid biosynthetic process GO:0009070 11 11 0,000 8,925E-03 0,01869381 ! histone deacetylase binding GO:0042826 11 11 0,000 8,925E-03 0,01868285 ! thymus development GO:0048538 12 11 0,000 8,925E-03 0,0186719 ! spleen development GO:0048536 12 11 0,000 8,925E-03 0,01866097 ! regulation of RNA stability GO:0043487 11 11 0,000 8,925E-03 0,01865005 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 12 11 0,000 8,925E-03 0,01863915 ! acid-thiol ligase activity GO:0016878 11 11 0,000 8,925E-03 0,01862825 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 11 11 0,000 8,925E-03 0,01861737 ! cerebellar cortex development GO:0021695 12 11 0,000 8,925E-03 0,0186065 ! ADP binding GO:0043531 11 11 0,000 8,925E-03 0,01859565 ! folic acid binding GO:0005542 11 11 0,000 8,925E-03 0,0185848 ! FK506 binding GO:0005528 11 11 0,000 8,925E-03 0,01857397 GO:0005527|macrolide binding, ! defense response to fungus GO:0050832 11 11 0,000 8,925E-03 0,01856316 ! extracellular matrix binding GO:0050840 13 11 0,000 8,925E-03 0,01855235 ! microspike assembly GO:0030035 13 11 0,000 8,925E-03 0,01854156 ! cytoplasmic sequestering of protein GO:0051220 11 11 0,000 8,925E-03 0,01853078 ! regulation of synapse structure and activity GO:0050803 11 11 0,000 8,925E-03 0,01852001 ! organ formation GO:0048645 12 11 0,000 8,925E-03 0,01850926 ! positive regulation of B cell proliferation GO:0030890 15 11 0,000 8,925E-03 0,01849851 ! embryonic hindlimb morphogenesis GO:0035116 11 11 0,000 8,925E-03 0,01848778 ! embryonic forelimb morphogenesis GO:0035115 11 11 0,000 8,925E-03 0,01847707 ! cellular copper ion homeostasis GO:0006878 12 11 0,000 8,925E-03 0,01846636 ! glycosaminoglycan catabolic process GO:0006027 11 11 0,000 8,925E-03 0,01845567 ! Golgi vesicle budding GO:0048194 11 11 0,000 8,925E-03 0,01844499 ! regulation of positive chemotaxis GO:0050926 11 11 0,000 8,925E-03 0,01843432 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 11 11 0,000 8,925E-03 0,01842366 ! ion channel inhibitor activity GO:0008200 13 11 0,000 8,925E-03 0,01841302 GO:0016248|channel inhibitor activity, ! positive regulation of transcription factor import into nucleus GO:0042993 12 11 0,000 8,925E-03 0,01840239 ! MAP kinase kinase activity GO:0004708 11 11 0,000 8,925E-03 0,01839177 GO:0004712|protein serine/threonine/tyrosine kinase activity, ! cation:amino acid symporter activity GO:0005416 11 11 0,000 8,925E-03 0,01838116 ! mannosyltransferase activity GO:0000030 11 11 0,000 8,925E-03 0,01837057 ! cAMP-dependent protein kinase activity GO:0004691 11 11 0,000 8,925E-03 0,01835999 ! FMN binding GO:0010181 11 11 0,000 8,925E-03 0,01834942 ! response to X-ray GO:0010165 12 11 0,000 8,925E-03 0,01833886 ! focal adhesion formation GO:0048041 13 11 0,000 8,925E-03 0,01832831 ! actin polymerization or depolymerization GO:0008154 13 11 0,000 8,925E-03 0,01831778 ! integrator complex GO:0032039 11 11 0,000 8,925E-03 0,01830726 ! L-glutamate transport GO:0015813 11 11 0,000 8,925E-03 0,01829675 GO:0015800|acidic amino acid transport, ! retinol binding GO:0019841 11 11 0,000 8,925E-03 0,01828625 ! regulation of organ growth GO:0046620 12 11 0,000 8,925E-03 0,01827577 ! regulation of cytokine production during immune response GO:0002718 11 11 0,000 8,925E-03 0,01826529 ! regulation of T cell mediated immunity GO:0002709 15 11 0,000 8,925E-03 0,01825483 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 11 11 0,000 8,925E-03 0,01824438 ! regulation of interleukin-8 production GO:0032677 12 11 0,000 8,925E-03 0,01823395 ! histone acetylation GO:0016573 11 11 0,000 8,925E-03 0,01822352 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 12 11 0,000 8,925E-03 0,01821311 ! delayed rectifier potassium channel activity GO:0005251 11 11 0,000 8,925E-03 0,01820271 ! organic cation transmembrane transporter activity GO:0015101 11 11 0,000 8,925E-03 0,01819232 ! chromatin silencing GO:0006342 11 11 0,000 8,925E-03 0,01818194 ! gland morphogenesis GO:0022612 12 11 0,000 8,925E-03 0,01817157 ! sulfate transmembrane transporter activity GO:0015116 11 11 0,000 8,925E-03 0,01816122 ! hexose transmembrane transporter activity GO:0015149 11 11 0,000 8,925E-03 0,01815088 ! icosanoid receptor activity GO:0004953 12 11 0,000 8,925E-03 0,01814055 GO:0004954|prostanoid receptor activity, ! non-G-protein coupled 7TM receptor activity GO:0004926 12 11 0,000 8,925E-03 0,01813023 ! negative regulation of neurological system process GO:0031645 12 11 0,000 8,925E-03 0,01811992 ! acid secretion GO:0046717 11 11 0,000 8,925E-03 0,01810962 ! nitric oxide mediated signal transduction GO:0007263 11 11 0,000 8,925E-03 0,01809934 ! thyroid hormone metabolic process GO:0042403 11 11 0,000 8,925E-03 0,01808907 ! quinone cofactor metabolic process GO:0042375 12 11 0,000 8,925E-03 0,01807881 ! insulin-like growth factor receptor binding GO:0005159 12 11 0,000 8,925E-03 0,01806856 ! midbody GO:0030496 11 11 0,000 8,925E-03 0,01805832 ! interferon-alpha/beta receptor binding GO:0005132 11 11 0,000 8,925E-03 0,0180481 ! cAMP-dependent protein kinase complex GO:0005952 11 11 0,000 8,925E-03 0,01803788 ! water channel activity GO:0015250 11 11 0,000 8,925E-03 0,01802768 ! response to nicotine GO:0035094 11 11 0,000 8,925E-03 0,01801749 ! response to cold GO:0009409 11 11 0,000 8,925E-03 0,01800731 ! adenylate cyclase activity GO:0004016 11 11 0,000 8,925E-03 0,01799714 ! 'de novo' protein folding GO:0006458 12 12 0,000 9,733E-03 0,01961485 ! centriole GO:0005814 12 12 0,000 9,733E-03 0,01960378 ! organellar large ribosomal subunit GO:0000315 13 12 0,000 9,733E-03 0,01959273 GO:0005762|mitochondrial large ribosomal subunit, ! cadmium ion binding GO:0046870 13 12 0,000 9,733E-03 0,0195817 ! folic acid and derivative biosynthetic process GO:0009396 12 12 0,000 9,733E-03 0,01957067 ! bone remodeling GO:0046849 12 12 0,000 9,733E-03 0,01955966 ! peroxisomal transport GO:0043574 12 12 0,000 9,733E-03 0,01954866 ! retina development in camera-type eye GO:0060041 13 12 0,000 9,733E-03 0,01953767 ! hair follicle morphogenesis GO:0031069 12 12 0,000 9,733E-03 0,01952669 ! voltage-gated sodium channel complex GO:0001518 13 12 0,000 9,733E-03 0,01951573 GO:0034706|sodium channel complex, ! regulation of excitatory postsynaptic membrane potential GO:0060079 14 12 0,000 9,733E-03 0,01950478 ! hippocampus development GO:0021766 12 12 0,000 9,733E-03 0,01949384 ! T cell selection GO:0045058 16 12 0,000 9,733E-03 0,01948291 ! cation:cation antiporter activity GO:0015491 12 12 0,000 9,733E-03 0,01947199 ! induction of apoptosis via death domain receptors GO:0008625 12 12 0,000 9,733E-03 0,01946109 ! T-tubule GO:0030315 13 12 0,000 9,733E-03 0,0194502 ! methionine metabolic process GO:0006555 13 12 0,000 9,733E-03 0,01943932 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 14 12 0,000 9,733E-03 0,01942846 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! peptide antigen binding GO:0042605 12 12 0,000 9,733E-03 0,0194176 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 9,733E-03 0,01940676 ! cell-cell junction assembly GO:0007043 12 12 0,000 9,733E-03 0,01939593 ! mitotic spindle organization GO:0007052 12 12 0,000 9,733E-03 0,01938511 ! fear response GO:0042596 12 12 0,000 9,733E-03 0,01937431 ! negative regulation of mitotic cell cycle GO:0045930 13 12 0,000 9,733E-03 0,01936352 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 9,733E-03 0,01935273 ! copper ion homeostasis GO:0055070 13 12 0,000 9,733E-03 0,01934196 ! lipoprotein receptor activity GO:0030228 12 12 0,000 9,733E-03 0,01933121 ! axon cargo transport GO:0008088 12 12 0,000 9,733E-03 0,01932046 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 13 12 0,000 9,733E-03 0,01930973 ! transcription elongation factor complex GO:0008023 13 12 0,000 9,733E-03 0,01929901 ! nuclear outer membrane GO:0005640 12 12 0,000 9,733E-03 0,0192883 ! beta-tubulin binding GO:0048487 12 12 0,000 9,733E-03 0,0192776 ! autonomic nervous system development GO:0048483 12 12 0,000 9,733E-03 0,01926691 ! positive regulation of interleukin-1 secretion GO:0050716 12 12 0,000 9,733E-03 0,01925624 GO:0050704|regulation of interleukin-1 secretion, ! exoribonuclease activity GO:0004532 12 12 0,000 9,733E-03 0,01924558 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! cofactor transport GO:0051181 12 12 0,000 9,733E-03 0,01923493 ! regulation of epidermis development GO:0045682 12 12 0,000 9,733E-03 0,01922429 ! protein-chromophore linkage GO:0018298 12 12 0,000 9,733E-03 0,01921366 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 12 12 0,000 9,733E-03 0,01920304 ! cell killing GO:0001906 12 12 0,000 9,733E-03 0,01919244 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 12 0,000 9,733E-03 0,01918185 ! lymphocyte homeostasis GO:0002260 14 12 0,000 9,733E-03 0,01917127 ! regulation of fatty acid oxidation GO:0046320 13 12 0,000 9,733E-03 0,0191607 ! detection of bacterium GO:0016045 13 12 0,000 9,733E-03 0,01915014 ! positive regulation of neuron apoptosis GO:0043525 12 12 0,000 9,733E-03 0,0191396 ! dystrophin-associated glycoprotein complex GO:0016010 14 12 0,000 9,733E-03 0,01912906 ! internal side of plasma membrane GO:0009898 14 12 0,000 9,733E-03 0,01911854 ! RNA 3'-end processing GO:0031123 12 12 0,000 9,733E-03 0,01910803 ! developmental induction GO:0031128 13 12 0,000 9,733E-03 0,01909753 GO:0045168|cell-cell signaling involved in cell fate specification, ! positive regulation of calcium-mediated signaling GO:0050850 14 12 0,000 9,733E-03 0,01908705 ! inner ear receptor cell differentiation GO:0060113 13 12 0,000 9,733E-03 0,01907657 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 9,733E-03 0,01906611 ! very-long-chain fatty acid metabolic process GO:0000038 12 12 0,000 9,733E-03 0,01905565 ! negative regulation of cell projection organization GO:0031345 14 12 0,000 9,733E-03 0,01904521 ! thyroid gland development GO:0030878 12 12 0,000 9,733E-03 0,01903478 ! non-recombinational repair GO:0000726 12 12 0,000 9,733E-03 0,01902436 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 12 12 0,000 9,733E-03 0,01901395 ! lipid localization GO:0010876 12 12 0,000 9,733E-03 0,01900356 GO:0019915|lipid storage, ! regulation of glycolysis GO:0006110 12 12 0,000 9,733E-03 0,01899317 ! negative regulation of transcription factor import into nucleus GO:0042992 12 12 0,000 9,733E-03 0,0189828 ! T cell proliferation GO:0042098 17 12 0,000 9,733E-03 0,01897244 ! negative regulation of protein amino acid phosphorylation GO:0001933 16 12 0,000 9,733E-03 0,01896209 ! receptor signaling protein tyrosine kinase activity GO:0004716 13 12 0,000 9,733E-03 0,01895175 ! two-component signal transduction system (phosphorelay) GO:0000160 13 12 0,000 9,733E-03 0,01894142 ! peptide or protein amino-terminal blocking GO:0018409 13 12 0,000 9,733E-03 0,01893111 ! drug transport GO:0015893 12 12 0,000 9,733E-03 0,0189208 ! GTP-dependent protein binding GO:0030742 12 12 0,000 9,733E-03 0,01891051 ! regulation of interleukin-6 biosynthetic process GO:0045408 12 12 0,000 9,733E-03 0,01890022 ! T cell receptor complex GO:0042101 12 12 0,000 9,733E-03 0,01888995 ! membrane protein proteolysis GO:0033619 13 12 0,000 9,733E-03 0,01887969 GO:0006509|membrane protein ectodomain proteolysis, ! protein disulfide oxidoreductase activity GO:0015035 12 12 0,000 9,733E-03 0,01886944 ! histone acetyltransferase complex GO:0000123 13 12 0,000 9,733E-03 0,0188592 ! dendritic spine GO:0043197 12 12 0,000 9,733E-03 0,01884897 ! ATP-binding cassette (ABC) transporter complex GO:0043190 12 12 0,000 9,733E-03 0,01883876 ! alpha-beta T cell activation GO:0046631 13 12 0,000 9,733E-03 0,01882855 ! organic anion transmembrane transporter activity GO:0008514 13 12 0,000 9,733E-03 0,01881836 ! vasoconstriction GO:0042310 13 12 0,000 9,733E-03 0,01880818 ! DNA unwinding during replication GO:0006268 12 12 0,000 9,733E-03 0,018798 ! cellular amino acid derivative catabolic process GO:0042219 16 12 0,000 9,733E-03 0,01878784 ! mRNA splice site selection GO:0006376 13 12 0,000 9,733E-03 0,01877769 ! phosphate transmembrane transporter activity GO:0015114 13 12 0,000 9,733E-03 0,01876755 ! trans-Golgi network transport vesicle membrane GO:0012510 15 12 0,000 9,733E-03 0,01875743 ! ubiquitin protein ligase binding GO:0031625 12 12 0,000 9,733E-03 0,01874731 ! monosaccharide transmembrane transporter activity GO:0015145 12 12 0,000 9,733E-03 0,0187372 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 12 12 0,000 9,733E-03 0,01872711 ! hexosaminidase activity GO:0015929 12 12 0,000 9,733E-03 0,01871702 ! diacylglycerol kinase activity GO:0004143 13 12 0,000 9,733E-03 0,01870695 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 9,733E-03 0,01869689 ! activation of NF-kappaB-inducing kinase activity GO:0007250 12 12 0,000 9,733E-03 0,01868683 ! protein kinase C binding GO:0005080 13 12 0,000 9,733E-03 0,01867679 ! catecholamine biosynthetic process GO:0042423 13 12 0,000 9,733E-03 0,01866676 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 15 12 0,000 9,733E-03 0,01865674 ! establishment or maintenance of apical/basal cell polarity GO:0035088 12 12 0,000 9,733E-03 0,01864673 ! L-fucose metabolic process GO:0042354 14 12 0,000 9,733E-03 0,01863673 ! acylglycerol O-acyltransferase activity GO:0016411 12 12 0,000 9,733E-03 0,01862675 ! C-acyltransferase activity GO:0016408 12 12 0,000 9,733E-03 0,01861677 ! steroid hydroxylase activity GO:0008395 12 12 0,000 9,733E-03 0,0186068 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 9,733E-03 0,01859685 ! calcium-activated potassium channel activity GO:0015269 14 12 0,000 9,733E-03 0,0185869 ! SWI/SNF-type complex GO:0070603 13 12 0,000 9,733E-03 0,01857697 GO:0016514|SWI/SNF complex, ! cilium part GO:0044441 12 12 0,000 9,733E-03 0,01856705 ! positive regulation of translation GO:0045727 13 13 0,000 0,01054044 0,02009606 ! ER-associated protein catabolic process GO:0030433 13 13 0,000 0,01054044 0,02008534 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01054044 0,02007463 ! superoxide anion generation GO:0042554 13 13 0,000 0,01054044 0,02006393 ! pteridine and derivative biosynthetic process GO:0042559 14 13 0,000 0,01054044 0,02005324 ! cis-Golgi network GO:0005801 14 13 0,000 0,01054044 0,02004256 ! regulation of S phase GO:0033261 17 13 0,000 0,01054044 0,02003189 ! regulation of chemokine production GO:0032642 13 13 0,000 0,01054044 0,02002124 ! phospholipid catabolic process GO:0009395 14 13 0,000 0,01054044 0,02001059 ! endothelial cell migration GO:0043542 13 13 0,000 0,01054044 0,01999996 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 13 13 0,000 0,01054044 0,01998934 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01054044 0,01997873 ! cartilage condensation GO:0001502 14 13 0,000 0,01054044 0,01996813 ! organelle fusion GO:0048284 14 13 0,000 0,01054044 0,01995754 ! positive regulation of lipid metabolic process GO:0045834 13 13 0,000 0,01054044 0,01994697 ! pseudouridine synthesis GO:0001522 14 13 0,000 0,01054044 0,0199364 ! negative regulation of gene expression, epigenetic GO:0045814 13 13 0,000 0,01054044 0,01992585 ! regulation of interleukin-2 biosynthetic process GO:0045076 13 13 0,000 0,01054044 0,0199153 ! negative regulation of proteolysis GO:0045861 13 13 0,000 0,01054044 0,01990477 ! regulation of mRNA processing GO:0050684 13 13 0,000 0,01054044 0,01989425 ! arginine metabolic process GO:0006525 13 13 0,000 0,01054044 0,01988374 ! WW domain binding GO:0050699 14 13 0,000 0,01054044 0,01987324 ! cholesterol binding GO:0015485 13 13 0,000 0,01054044 0,01986276 ! negative regulation of microtubule depolymerization GO:0007026 15 13 0,000 0,01054044 0,01985228 GO:0031114|regulation of microtubule depolymerization, ! Golgi organization GO:0007030 16 13 0,000 0,01054044 0,01984182 ! negative regulation of endothelial cell migration GO:0010596 13 13 0,000 0,01054044 0,01983136 ! integral to peroxisomal membrane GO:0005779 13 13 0,000 0,01054044 0,01982092 GO:0031231|intrinsic to peroxisomal membrane, ! integral to membrane of membrane fraction GO:0000299 14 13 0,000 0,01054044 0,01981049 ! regulation of heart rate GO:0002027 14 13 0,000 0,01054044 0,01980007 ! positive regulation of carbohydrate metabolic process GO:0045913 14 13 0,000 0,01054044 0,01978966 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 14 13 0,000 0,01054044 0,01977926 ! negative regulation of immune response GO:0050777 17 13 0,000 0,01054044 0,01976887 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 13 0,000 0,01054044 0,01975849 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01054044 0,01974812 ! response to estradiol stimulus GO:0032355 14 13 0,000 0,01054044 0,01973777 ! anaphase-promoting complex GO:0005680 13 13 0,000 0,01054044 0,01972742 ! nucleotide diphosphatase activity GO:0004551 13 13 0,000 0,01054044 0,01971709 ! NADP metabolic process GO:0006739 13 13 0,000 0,01054044 0,01970677 ! regulation of erythrocyte differentiation GO:0045646 13 13 0,000 0,01054044 0,01969645 ! intestinal absorption GO:0050892 13 13 0,000 0,01054044 0,01968615 ! eukaryotic cell surface binding GO:0043499 14 13 0,000 0,01054044 0,01967586 ! digestive tract morphogenesis GO:0048546 13 13 0,000 0,01054044 0,01966558 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 14 13 0,000 0,01054044 0,01965531 ! regulation of cellular carbohydrate catabolic process GO:0043471 14 13 0,000 0,01054044 0,01964505 GO:0043470|regulation of carbohydrate catabolic process, ! tropomyosin binding GO:0005523 13 13 0,000 0,01054044 0,01963481 ! carbon-sulfur lyase activity GO:0016846 13 13 0,000 0,01054044 0,01962457 ! positive regulation of protein polymerization GO:0032273 13 13 0,000 0,01054044 0,01961434 ! insulin secretion GO:0030073 13 13 0,000 0,01054044 0,01960413 ! positive regulation of cellular catabolic process GO:0031331 14 13 0,000 0,01054044 0,01959392 ! G1 phase of mitotic cell cycle GO:0000080 13 13 0,000 0,01054044 0,01958373 ! replisome GO:0030894 14 13 0,000 0,01054044 0,01957354 GO:0043601|nuclear replisome, ! regulation of nitric-oxide synthase activity GO:0050999 13 13 0,000 0,01054044 0,01956337 ! double-strand break repair via homologous recombination GO:0000724 13 13 0,000 0,01054044 0,01955321 GO:0000725|recombinational repair, ! copper ion transport GO:0006825 13 13 0,000 0,01054044 0,01954306 ! regulation of cell-cell adhesion GO:0022407 13 13 0,000 0,01054044 0,01953291 ! forelimb morphogenesis GO:0035136 13 13 0,000 0,01054044 0,01952278 ! mating GO:0007618 13 13 0,000 0,01054044 0,01951266 ! phosphatidylinositol phosphate kinase activity GO:0016307 14 13 0,000 0,01054044 0,01950255 ! MAP kinase activity GO:0004707 14 13 0,000 0,01054044 0,01949245 ! cytokine biosynthetic process GO:0042089 13 13 0,000 0,01054044 0,01948236 ! ventral spinal cord development GO:0021517 13 13 0,000 0,01054044 0,01947228 ! prenyltransferase activity GO:0004659 14 13 0,000 0,01054044 0,01946222 ! regulation of skeletal muscle fiber development GO:0048742 13 13 0,000 0,01054044 0,01945216 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 15 13 0,000 0,01054044 0,01944211 ! protein kinase C activity GO:0004697 15 13 0,000 0,01054044 0,01943207 ! oligodendrocyte differentiation GO:0048709 13 13 0,000 0,01054044 0,01942205 ! water transporter activity GO:0005372 13 13 0,000 0,01054044 0,01941203 ! exocrine system development GO:0035272 14 13 0,000 0,01054044 0,01940202 ! dicarboxylic acid transmembrane transporter activity GO:0005310 13 13 0,000 0,01054044 0,01939203 ! monoamine transport GO:0015844 13 13 0,000 0,01054044 0,01938204 ! CoA hydrolase activity GO:0016289 13 13 0,000 0,01054044 0,01937207 ! embryo implantation GO:0007566 13 13 0,000 0,01054044 0,0193621 ! G1/S transition checkpoint GO:0031575 13 13 0,000 0,01054044 0,01935215 ! positive regulation of alpha-beta T cell differentiation GO:0046638 13 13 0,000 0,01054044 0,0193422 ! immunoglobulin binding GO:0019865 13 13 0,000 0,01054044 0,01933227 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01054044 0,01932234 ! anchored to plasma membrane GO:0046658 14 13 0,000 0,01054044 0,01931243 ! MHC class I protein binding GO:0042288 13 13 0,000 0,01054044 0,01930253 ! calcium channel regulator activity GO:0005246 14 13 0,000 0,01054044 0,01929263 ! neuroblast proliferation GO:0007405 13 13 0,000 0,01054044 0,01928275 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01054044 0,01927287 ! response to gamma radiation GO:0010332 13 13 0,000 0,01054044 0,01926301 ! sarcomere organization GO:0045214 13 13 0,000 0,01054044 0,01925316 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 15 13 0,000 0,01054044 0,01924332 ! cAMP binding GO:0030552 13 13 0,000 0,01054044 0,01923348 ! fucosyltransferase activity GO:0008417 14 13 0,000 0,01054044 0,01922366 ! cilium assembly GO:0042384 13 13 0,000 0,01054044 0,01921385 ! negative regulation of leukocyte proliferation GO:0070664 13 13 0,000 0,01054044 0,01920404 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! bacterial binding GO:0008367 13 13 0,000 0,01054044 0,01919425 ! regulation of NF-kappaB import into nucleus GO:0042345 13 13 0,000 0,01054044 0,01918447 ! acrosome reaction GO:0007340 13 13 0,000 0,01054044 0,01917469 ! microtubule-based flagellum GO:0009434 13 13 0,000 0,01054044 0,01916493 ! nucleolar part GO:0044452 13 13 0,000 0,01054044 0,01915518 ! axoneme part GO:0044447 13 13 0,000 0,01054044 0,01914543 ! tRNA modification GO:0006400 14 14 0,000 0,01134701 0,02059999 ! positive regulation of blood pressure GO:0045777 15 14 0,000 0,01134701 0,02058953 ! transferase activity, transferring amino-acyl groups GO:0016755 14 14 0,000 0,01134701 0,02057907 ! negative regulation of bone remodeling GO:0046851 14 14 0,000 0,01134701 0,02056862 ! 2'-deoxyribonucleotide metabolic process GO:0009394 15 14 0,000 0,01134701 0,02055819 GO:0019692|deoxyribose phosphate metabolic process, ! transcription from RNA polymerase III promoter GO:0006383 14 14 0,000 0,01134701 0,02054776 ! guanylate kinase activity GO:0004385 16 14 0,000 0,01134701 0,02053735 ! striated muscle thin filament GO:0005865 15 14 0,000 0,01134701 0,02052694 ! patterning of blood vessels GO:0001569 14 14 0,000 0,01134701 0,02051655 ! mechanoreceptor differentiation GO:0042490 15 14 0,000 0,01134701 0,02050617 ! palate development GO:0060021 15 14 0,000 0,01134701 0,02049579 ! centrosome cycle GO:0007098 14 14 0,000 0,01134701 0,02048543 ! regulation of defense response to virus GO:0050688 14 14 0,000 0,01134701 0,02047508 ! cAMP-dependent protein kinase regulator activity GO:0008603 14 14 0,000 0,01134701 0,02046474 ! ephrin receptor activity GO:0005003 16 14 0,000 0,01134701 0,02045441 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01134701 0,02044409 ! glycine metabolic process GO:0006544 15 14 0,000 0,01134701 0,02043378 ! plasma membrane organization GO:0007009 14 14 0,000 0,01134701 0,02042348 ! tyrosine metabolic process GO:0006570 16 14 0,000 0,01134701 0,02041319 ! response to retinoic acid GO:0032526 14 14 0,000 0,01134701 0,02040291 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 16 14 0,000 0,01134701 0,02039264 ! lysosomal transport GO:0007041 14 14 0,000 0,01134701 0,02038239 ! rough endoplasmic reticulum GO:0005791 14 14 0,000 0,01134701 0,02037214 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 14 14 0,000 0,01134701 0,0203619 ! regulation of the force of heart contraction GO:0002026 15 14 0,000 0,01134701 0,02035168 ! bone mineralization GO:0030282 14 14 0,000 0,01134701 0,02034146 ! protein kinase activator activity GO:0030295 14 14 0,000 0,01134701 0,02033125 ! NLS-bearing substrate import into nucleus GO:0006607 15 14 0,000 0,01134701 0,02032106 ! cerebellum development GO:0021549 15 14 0,000 0,01134701 0,02031087 ! G1 phase GO:0051318 14 14 0,000 0,01134701 0,02030069 ! negative regulation of protein secretion GO:0050709 14 14 0,000 0,01134701 0,02029053 ! water homeostasis GO:0030104 14 14 0,000 0,01134701 0,02028037 ! peptide hormone binding GO:0017046 14 14 0,000 0,01134701 0,02027023 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01134701 0,02026009 ! glutamine family amino acid biosynthetic process GO:0009084 15 14 0,000 0,01134701 0,02024997 ! regulation of ATPase activity GO:0043462 15 14 0,000 0,01134701 0,02023985 ! racemase and epimerase activity GO:0016854 14 14 0,000 0,01134701 0,02022975 ! regulation of leukocyte mediated cytotoxicity GO:0001910 18 14 0,000 0,01134701 0,02021965 ! positive regulation of calcium ion transport GO:0051928 17 14 0,000 0,01134701 0,02020957 ! regulation of calcium-mediated signaling GO:0050848 16 14 0,000 0,01134701 0,02019949 ! positive regulation of synaptic transmission GO:0050806 14 14 0,000 0,01134701 0,02018943 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 16 14 0,000 0,01134701 0,02017938 ! lactation GO:0007595 15 14 0,000 0,01134701 0,02016933 ! reproductive cellular process GO:0048610 14 14 0,000 0,01134701 0,0201593 ! positive regulation of cell killing GO:0031343 18 14 0,000 0,01134701 0,02014927 ! sulfur amino acid biosynthetic process GO:0000097 15 14 0,000 0,01134701 0,02013926 ! dicarboxylic acid transport GO:0006835 14 14 0,000 0,01134701 0,02012925 ! regulation of B cell proliferation GO:0030888 18 14 0,000 0,01134701 0,02011926 ! inorganic anion exchanger activity GO:0005452 15 14 0,000 0,01134701 0,02010927 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 15 14 0,000 0,01134701 0,0200993 ! negative regulation of cytokine biosynthetic process GO:0042036 14 14 0,000 0,01134701 0,02008933 ! negative regulation of ion transport GO:0043271 14 14 0,000 0,01134701 0,02007938 ! retinoic acid receptor binding GO:0042974 14 14 0,000 0,01134701 0,02006943 ! startle response GO:0001964 14 14 0,000 0,01134701 0,0200595 ! 2 iron, 2 sulfur cluster binding GO:0051537 14 14 0,000 0,01134701 0,02004957 ! activation of MAPKK activity GO:0000186 15 14 0,000 0,01134701 0,02003966 ! response to hexose stimulus GO:0009746 14 14 0,000 0,01134701 0,02002975 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! cytokine metabolic process GO:0042107 14 14 0,000 0,01134701 0,02001985 ! organic alcohol transport GO:0015850 15 14 0,000 0,01134701 0,02000997 ! preassembly of GPI anchor in ER membrane GO:0016254 15 14 0,000 0,01134701 0,02000009 ! calcium ion transmembrane transporter activity GO:0015085 16 14 0,000 0,01134701 0,01999022 ! eukaryotic translation initiation factor 4F complex GO:0016281 14 14 0,000 0,01134701 0,01998037 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01134701 0,01997052 ! L-amino acid transport GO:0015807 14 14 0,000 0,01134701 0,01996068 ! microfilament motor activity GO:0000146 14 14 0,000 0,01134701 0,01995085 ! stem cell development GO:0048864 14 14 0,000 0,01134701 0,01994104 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 15 14 0,000 0,01134701 0,01993123 ! DNA replication initiation GO:0006270 14 14 0,000 0,01134701 0,01992143 ! T cell differentiation in the thymus GO:0033077 18 14 0,000 0,01134701 0,01991164 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01134701 0,01990186 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01134701 0,01989209 ! calcium activated cation channel activity GO:0005227 16 14 0,000 0,01134701 0,01988233 ! sulfuric ester hydrolase activity GO:0008484 15 14 0,000 0,01134701 0,01987258 ! serotonin receptor activity GO:0004993 14 14 0,000 0,01134701 0,01986284 ! positive regulation of bone mineralization GO:0030501 15 14 0,000 0,01134701 0,0198531 ! synaptic transmission, cholinergic GO:0007271 15 14 0,000 0,01134701 0,01984338 ! dopamine metabolic process GO:0042417 17 14 0,000 0,01134701 0,01983367 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01134701 0,01982397 ! ion gated channel activity GO:0022839 16 14 0,000 0,01134701 0,01981427 ! male genitalia development GO:0030539 14 14 0,000 0,01134701 0,01980459 ! regulation of axon extension GO:0030516 15 14 0,000 0,01134701 0,01979491 ! regulation of BMP signaling pathway GO:0030510 14 14 0,000 0,01134701 0,01978525 ! estrogen receptor signaling pathway GO:0030520 14 14 0,000 0,01134701 0,01977559 ! interleukin-1 receptor binding GO:0005149 14 14 0,000 0,01134701 0,01976594 ! defense response to virus GO:0051607 19 14 0,000 0,01134701 0,01975631 ! cadherin binding GO:0045296 16 14 0,000 0,01134701 0,01974668 ! negative regulation of hormone secretion GO:0046888 16 15 0,000 0,01215298 0,02113896 ! nuclear replication fork GO:0043596 16 15 0,000 0,01215298 0,02112867 ! phosphoinositide phosphorylation GO:0046854 16 15 0,000 0,01215298 0,02111839 GO:0046834|lipid phosphorylation, ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01215298 0,02110812 ! cardiac muscle contraction GO:0060048 16 15 0,000 0,01215298 0,02109786 ! polysome GO:0005844 16 15 0,000 0,01215298 0,02108761 ! mitotic chromosome condensation GO:0007076 15 15 0,000 0,01215298 0,02107736 ! regulation of viral genome replication GO:0045069 15 15 0,000 0,01215298 0,02106713 ! regulation of survival gene product expression GO:0045884 15 15 0,000 0,01215298 0,02105691 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 15 0,000 0,01215298 0,0210467 ! glycoprotein catabolic process GO:0006516 15 15 0,000 0,01215298 0,0210365 ! DNA duplex unwinding GO:0032508 15 15 0,000 0,01215298 0,02102631 GO:0032392|DNA geometric change, ! glutamine metabolic process GO:0006541 16 15 0,000 0,01215298 0,02101612 ! proton-transporting V-type ATPase complex GO:0033176 15 15 0,000 0,01215298 0,02100595 ! response to vitamin A GO:0033189 15 15 0,000 0,01215298 0,02099579 ! protease binding GO:0002020 16 15 0,000 0,01215298 0,02098564 ! regulation of ion transmembrane transporter activity GO:0032412 15 15 0,000 0,01215298 0,02097549 ! actin filament bundle formation GO:0051017 15 15 0,000 0,01215298 0,02096536 ! calcium ion-dependent exocytosis GO:0017156 15 15 0,000 0,01215298 0,02095524 ! purine nucleoside monophosphate metabolic process GO:0009126 16 15 0,000 0,01215298 0,02094512 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 15 15 0,000 0,01215298 0,02093502 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01215298 0,02092492 ! positive regulation of biomineral formation GO:0070169 16 15 0,000 0,01215298 0,02091484 ! positive regulation of oxidoreductase activity GO:0051353 15 15 0,000 0,01215298 0,02090477 ! filopodium GO:0030175 15 15 0,000 0,01215298 0,0208947 ! negative regulation of inflammatory response GO:0050728 15 15 0,000 0,01215298 0,02088465 ! positive regulation of transmission of nerve impulse GO:0051971 15 15 0,000 0,01215298 0,0208746 ! branched chain family amino acid metabolic process GO:0009081 15 15 0,000 0,01215298 0,02086456 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01215298 0,02085454 ! heme biosynthetic process GO:0006783 15 15 0,000 0,01215298 0,02084452 ! SMAD binding GO:0046332 16 15 0,000 0,01215298 0,02083451 ! nerve development GO:0021675 16 15 0,000 0,01215298 0,02082452 ! epithelial to mesenchymal transition GO:0001837 16 15 0,000 0,01215298 0,02081453 ! mannose binding GO:0005537 15 15 0,000 0,01215298 0,02080455 ! phosphoprotein binding GO:0051219 17 15 0,000 0,01215298 0,02079458 ! mismatched DNA binding GO:0030983 15 15 0,000 0,01215298 0,02078462 ! antigen receptor-mediated signaling pathway GO:0050851 21 15 0,000 0,01215298 0,02077467 ! regulation of skeletal muscle tissue development GO:0048641 15 15 0,000 0,01215298 0,02076473 ! synaptonemal complex GO:0000795 15 15 0,000 0,01215298 0,0207548 ! N-terminal protein amino acid modification GO:0031365 16 15 0,000 0,01215298 0,02074488 ! positive regulation of protein complex assembly GO:0031334 15 15 0,000 0,01215298 0,02073497 ! water transport GO:0006833 15 15 0,000 0,01215298 0,02072507 GO:0042044|fluid transport, ! phosphatidylinositol metabolic process GO:0046488 16 15 0,000 0,01215298 0,02071518 ! viral genome replication GO:0019079 15 15 0,000 0,01215298 0,02070529 ! phosphatidylcholine metabolic process GO:0046470 17 15 0,000 0,01215298 0,02069542 ! inositol metabolic process GO:0006020 15 15 0,000 0,01215298 0,02068555 ! sulfate transport GO:0008272 15 15 0,000 0,01215298 0,0206757 ! protein-lipid complex GO:0032994 15 15 0,000 0,01215298 0,02066585 GO:0034358|plasma lipoprotein particle, ! positive regulation of ion transport GO:0043270 18 15 0,000 0,01215298 0,02065602 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 15 15 0,000 0,01215298 0,02064619 ! heart looping GO:0001947 15 15 0,000 0,01215298 0,02063637 ! isoprenoid biosynthetic process GO:0008299 16 15 0,000 0,01215298 0,02062657 ! protein histidine kinase activity GO:0004673 16 15 0,000 0,01215298 0,02061677 GO:0000155|two-component sensor activity, ! cardiac muscle tissue development GO:0048738 15 15 0,000 0,01215298 0,02060698 ! regulation of striated muscle contraction GO:0006942 16 15 0,000 0,01215298 0,0205972 ! response to osmotic stress GO:0006970 16 15 0,000 0,01215298 0,02058743 ! fructose metabolic process GO:0006000 15 15 0,000 0,01215298 0,02057766 ! ubiquitin binding GO:0043130 15 15 0,000 0,01215298 0,02056791 ! vesicle coating GO:0006901 16 15 0,000 0,01215298 0,02055817 ! DNA integration GO:0015074 16 15 0,000 0,01215298 0,02054843 ! alcohol binding GO:0043178 16 15 0,000 0,01215298 0,02053871 ! disulfide oxidoreductase activity GO:0015036 15 15 0,000 0,01215298 0,02052899 ! intermediate filament cytoskeleton organization GO:0045104 16 15 0,000 0,01215298 0,02051929 ! regulation of vasodilation GO:0042312 15 15 0,000 0,01215298 0,02050959 ! genitalia development GO:0048806 15 15 0,000 0,01215298 0,0204999 ! structural constituent of eye lens GO:0005212 15 15 0,000 0,01215298 0,02049022 ! regulation of monooxygenase activity GO:0032768 15 15 0,000 0,01215298 0,02048055 ! voltage-gated sodium channel activity GO:0005248 17 15 0,000 0,01215298 0,02047089 ! ribonucleoprotein binding GO:0043021 16 15 0,000 0,01215298 0,02046124 ! proton-transporting ATP synthase complex GO:0045259 15 15 0,000 0,01215298 0,0204516 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 15 15 0,000 0,01215298 0,02044197 ! regulation of immunoglobulin production GO:0002637 19 15 0,000 0,01215298 0,02043234 ! retinoic acid receptor activity GO:0003708 15 15 0,000 0,01215298 0,02042273 ! receptor activator activity GO:0030546 15 15 0,000 0,01215298 0,02041312 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 15 15 0,000 0,01215298 0,02040352 ! protein transmembrane transporter activity GO:0008320 15 15 0,000 0,01215298 0,02039394 ! histone binding GO:0042393 15 15 0,000 0,01215298 0,02038436 ! phosphoinositide 3-kinase activity GO:0035004 16 15 0,000 0,01215298 0,02037479 ! sialyltransferase activity GO:0008373 15 15 0,000 0,01215298 0,02036522 ! drug transporter activity GO:0015238 15 15 0,000 0,01215298 0,02035567 ! negative regulation of homeostatic process GO:0032845 15 15 0,000 0,01215298 0,02034613 ! phosphoinositide 3-kinase complex GO:0005942 16 15 0,000 0,01215298 0,0203366 ! binding of sperm to zona pellucida GO:0007339 16 15 0,000 0,01215298 0,02032707 ! peptide hormone processing GO:0016486 17 15 0,000 0,01215298 0,02031755 ! aldo-keto reductase activity GO:0004033 15 15 0,000 0,01215298 0,02030805 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01215298 0,02029855 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 16 16 0,000 0,01295835 0,02163359 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01295835 0,02162348 ! positive regulation of hormone secretion GO:0046887 17 16 0,000 0,01295835 0,02161338 ! protein amino acid ADP-ribosylation GO:0006471 18 16 0,000 0,01295835 0,02160329 ! response to vitamin GO:0033273 16 16 0,000 0,01295835 0,02159321 ! gene silencing by RNA GO:0031047 16 16 0,000 0,01295835 0,02158314 ! regulation of postsynaptic membrane potential GO:0060078 18 16 0,000 0,01295835 0,02157308 ! kinesin complex GO:0005871 16 16 0,000 0,01295835 0,02156302 ! cornified envelope GO:0001533 18 16 0,000 0,01295835 0,02155298 ! regulation of transmembrane transporter activity GO:0022898 16 16 0,000 0,01295835 0,02154295 GO:0032409|regulation of transporter activity, ! negative regulation of epithelial cell proliferation GO:0050680 17 16 0,000 0,01295835 0,02153292 ! pyrimidine ribonucleotide metabolic process GO:0009218 18 16 0,000 0,01295835 0,02152291 ! pituitary gland development GO:0021983 16 16 0,000 0,01295835 0,0215129 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 18 16 0,000 0,01295835 0,0215029 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 19 16 0,000 0,01295835 0,02149292 ! cell-substrate junction assembly GO:0007044 18 16 0,000 0,01295835 0,02148294 ! peptidyl-serine phosphorylation GO:0018105 16 16 0,000 0,01295835 0,02147297 ! branching involved in ureteric bud morphogenesis GO:0001658 16 16 0,000 0,01295835 0,02146301 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 16 16 0,000 0,01295835 0,02145306 ! nucleobase metabolic process GO:0009112 19 16 0,000 0,01295835 0,02144312 ! beta-catenin binding GO:0008013 17 16 0,000 0,01295835 0,02143319 ! regulation of steroid metabolic process GO:0019218 17 16 0,000 0,01295835 0,02142326 ! neuron recognition GO:0008038 17 16 0,000 0,01295835 0,02141335 ! oogenesis GO:0048477 19 16 0,000 0,01295835 0,02140345 ! low-density lipoprotein binding GO:0030169 17 16 0,000 0,01295835 0,02139355 ! clathrin vesicle coat GO:0030125 19 16 0,000 0,01295835 0,02138367 ! COPI-coated vesicle GO:0030137 16 16 0,000 0,01295835 0,02137379 ! sphingolipid biosynthetic process GO:0030148 16 16 0,000 0,01295835 0,02136392 ! vitamin transport GO:0051180 16 16 0,000 0,01295835 0,02135406 ! folic acid and derivative metabolic process GO:0006760 16 16 0,000 0,01295835 0,02134421 ! organic cation transport GO:0015695 16 16 0,000 0,01295835 0,02133437 ! proximal/distal pattern formation GO:0009954 16 16 0,000 0,01295835 0,02132454 ! regulation of glucose import GO:0046324 17 16 0,000 0,01295835 0,02131472 GO:0010827|regulation of glucose transport, ! aromatic compound biosynthetic process GO:0019438 17 16 0,000 0,01295835 0,0213049 ! aromatic compound catabolic process GO:0019439 18 16 0,000 0,01295835 0,0212951 ! tRNA binding GO:0000049 16 16 0,000 0,01295835 0,0212853 ! regulation of cell killing GO:0031341 20 16 0,000 0,01295835 0,02127552 ! negative regulation of defense response GO:0031348 16 16 0,000 0,01295835 0,02126574 ! regulation of neuronal synaptic plasticity GO:0048168 16 16 0,000 0,01295835 0,02125597 ! hindlimb morphogenesis GO:0035137 16 16 0,000 0,01295835 0,02124621 ! bile acid metabolic process GO:0008206 16 16 0,000 0,01295835 0,02123646 ! axis specification GO:0009798 16 16 0,000 0,01295835 0,02122672 ! adult walking behavior GO:0007628 17 16 0,000 0,01295835 0,02121699 ! C-C chemokine binding GO:0019957 16 16 0,000 0,01295835 0,02120726 GO:0016493|C-C chemokine receptor activity, ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 18 16 0,000 0,01295835 0,02119755 ! protein phosphatase binding GO:0019903 17 16 0,000 0,01295835 0,02118784 ! acyl-CoA dehydrogenase activity GO:0003995 16 16 0,000 0,01295835 0,02117815 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01295835 0,02116846 ! SH2 domain binding GO:0042169 19 16 0,000 0,01295835 0,02115878 ! UDP-galactosyltransferase activity GO:0035250 17 16 0,000 0,01295835 0,02114911 ! RNA methyltransferase activity GO:0008173 16 16 0,000 0,01295835 0,02113945 ! neutral amino acid transport GO:0015804 16 16 0,000 0,01295835 0,0211298 ! glucuronosyltransferase activity GO:0015020 17 16 0,000 0,01295835 0,02112015 ! regulation of alpha-beta T cell differentiation GO:0046637 16 16 0,000 0,01295835 0,02111052 ! cellular pigmentation GO:0033059 16 16 0,000 0,01295835 0,02110089 ! mannosidase activity GO:0015923 19 16 0,000 0,01295835 0,02109127 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 16 16 0,000 0,01295835 0,02108166 ! negative regulation of tissue remodeling GO:0034104 16 16 0,000 0,01295835 0,02107206 ! positive regulation of neurological system process GO:0031646 16 16 0,000 0,01295835 0,02106247 ! neuromuscular synaptic transmission GO:0007274 16 16 0,000 0,01295835 0,02105289 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01295835 0,02104332 ! sperm-egg recognition GO:0035036 17 16 0,000 0,01295835 0,02103375 ! axoneme GO:0005930 16 16 0,000 0,01295835 0,02102419 ! anion exchanger activity GO:0015380 18 17 0,000 0,01376311 0,02231974 ! neuron maturation GO:0042551 18 17 0,000 0,01376311 0,0223096 ! metencephalon development GO:0022037 18 17 0,000 0,01376311 0,02229948 ! reciprocal meiotic recombination GO:0007131 17 17 0,000 0,01376311 0,02228937 ! hemoglobin complex GO:0005833 18 17 0,000 0,01376311 0,02227927 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 17 17 0,000 0,01376311 0,02226917 ! protein amino acid acetylation GO:0006473 19 17 0,000 0,01376311 0,02225909 ! positive regulation of nucleocytoplasmic transport GO:0046824 18 17 0,000 0,01376311 0,02224901 ! regulation of neurotransmitter secretion GO:0046928 18 17 0,000 0,01376311 0,02223894 ! striated muscle thick filament GO:0005863 19 17 0,000 0,01376311 0,02222888 GO:0032982|myosin filament, ! gamma-aminobutyric acid signaling pathway GO:0007214 17 17 0,000 0,01376311 0,02221883 ! glial cell development GO:0021782 17 17 0,000 0,01376311 0,02220879 ! regulation of muscle cell differentiation GO:0051147 17 17 0,000 0,01376311 0,02219876 ! pancreas development GO:0031016 17 17 0,000 0,01376311 0,02218874 ! acetylcholine receptor activity GO:0015464 17 17 0,000 0,01376311 0,02217873 ! nuclear heterochromatin GO:0005720 18 17 0,000 0,01376311 0,02216872 ! calcium-dependent protein binding GO:0048306 19 17 0,000 0,01376311 0,02215873 ! cerebral cortex development GO:0021987 17 17 0,000 0,01376311 0,02214874 ! cellular response to starvation GO:0009267 18 17 0,000 0,01376311 0,02213877 ! signal sequence binding GO:0005048 17 17 0,000 0,01376311 0,0221288 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 17 17 0,000 0,01376311 0,02211884 ! cellular macromolecular complex disassembly GO:0034623 18 17 0,000 0,01376311 0,02210889 ! transforming growth factor beta receptor activity GO:0005024 17 17 0,000 0,01376311 0,02209895 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01376311 0,02208902 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 17 17 0,000 0,01376311 0,02207909 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 17 0,000 0,01376311 0,02206918 ! actin filament bundle GO:0032432 17 17 0,000 0,01376311 0,02205927 GO:0001725|stress fiber, ! small nucleolar ribonucleoprotein complex GO:0005732 17 17 0,000 0,01376311 0,02204938 ! response to lipopolysaccharide GO:0032496 17 17 0,000 0,01376311 0,02203949 ! plasma membrane fusion GO:0045026 18 17 0,000 0,01376311 0,02202961 ! regulation of protein binding GO:0043393 18 17 0,000 0,01376311 0,02201974 ! recycling endosome GO:0055037 18 17 0,000 0,01376311 0,02200988 ! prostaglandin metabolic process GO:0006693 18 17 0,000 0,01376311 0,02200003 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 19 17 0,000 0,01376311 0,02199018 ! regulation of immunoglobulin mediated immune response GO:0002889 21 17 0,000 0,01376311 0,02198035 GO:0002712|regulation of B cell mediated immunity, ! receptor signaling complex scaffold activity GO:0030159 17 17 0,000 0,01376311 0,02197052 ! positive regulation of cytokine secretion GO:0050715 17 17 0,000 0,01376311 0,02196071 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 17 0,000 0,01376311 0,0219509 ! sphingolipid catabolic process GO:0030149 18 17 0,000 0,01376311 0,0219411 ! steroid catabolic process GO:0006706 17 17 0,000 0,01376311 0,02193131 ! oxygen transport GO:0015671 18 17 0,000 0,01376311 0,02192153 GO:0005344|oxygen transporter activity, ! phosphatidylinositol binding GO:0005545 19 17 0,000 0,01376311 0,02191175 ! hyaluronic acid binding GO:0005540 17 17 0,000 0,01376311 0,02190199 ! negative regulation of T cell activation GO:0050868 17 17 0,000 0,01376311 0,02189223 ! regulation of glucose metabolic process GO:0010906 17 17 0,000 0,01376311 0,02188248 ! G2/M transition of mitotic cell cycle GO:0000086 17 17 0,000 0,01376311 0,02187275 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 17 17 0,000 0,01376311 0,02186302 ! glycosaminoglycan biosynthetic process GO:0006024 17 17 0,000 0,01376311 0,02185329 ! MAP kinase kinase kinase activity GO:0004709 18 17 0,000 0,01376311 0,02184358 ! L-ascorbic acid binding GO:0031418 17 17 0,000 0,01376311 0,02183388 ! negative regulation of endothelial cell proliferation GO:0001937 17 17 0,000 0,01376311 0,02182418 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 18 17 0,000 0,01376311 0,0218145 ! photoreceptor cell maintenance GO:0045494 17 17 0,000 0,01376311 0,02180482 ! response to carbohydrate stimulus GO:0009743 17 17 0,000 0,01376311 0,02179515 ! calmodulin-dependent protein kinase activity GO:0004683 19 17 0,000 0,01376311 0,02178549 ! fucose metabolic process GO:0006004 19 17 0,000 0,01376311 0,02177584 ! D-ribose metabolic process GO:0006014 18 17 0,000 0,01376311 0,02176619 ! membrane budding GO:0006900 18 17 0,000 0,01376311 0,02175656 ! AMP binding GO:0016208 17 17 0,000 0,01376311 0,02174693 ! nuclear ubiquitin ligase complex GO:0000152 17 17 0,000 0,01376311 0,02173731 ! body fluid secretion GO:0007589 18 17 0,000 0,01376311 0,0217277 ! response to fungus GO:0009620 17 17 0,000 0,01376311 0,0217181 ! positive regulation of alpha-beta T cell activation GO:0046635 21 17 0,000 0,01376311 0,02170851 ! intermediate filament-based process GO:0045103 18 17 0,000 0,01376311 0,02169892 ! rRNA binding GO:0019843 17 17 0,000 0,01376311 0,02168935 ! regulation of interleukin-2 production GO:0032663 17 17 0,000 0,01376311 0,02167978 ! voltage-gated chloride channel activity GO:0005247 17 17 0,000 0,01376311 0,02167022 ! DNA fragmentation involved in apoptosis GO:0006309 17 17 0,000 0,01376311 0,02166067 ! neutrophil chemotaxis GO:0030593 18 17 0,000 0,01376311 0,02165113 ! long-chain fatty acid transport GO:0015909 17 17 0,000 0,01376311 0,02164159 ! tissue regeneration GO:0042246 17 17 0,000 0,01376311 0,02163207 ! detection of biotic stimulus GO:0009595 18 17 0,000 0,01376311 0,02162255 ! muscle maintenance GO:0046716 18 17 0,000 0,01376311 0,02161304 ! cell-cell junction organization GO:0045216 17 17 0,000 0,01376311 0,02160354 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 17 17 0,000 0,01376311 0,02159405 ! somatic recombination of immunoglobulin gene segments GO:0016447 17 17 0,000 0,01376311 0,02158457 ! cell-cell adherens junction GO:0005913 17 17 0,000 0,01376311 0,02157509 ! triacylglycerol lipase activity GO:0004806 17 17 0,000 0,01376311 0,02156563 ! ATP-dependent DNA helicase activity GO:0004003 17 17 0,000 0,01376311 0,02155617 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01456727 0,02280566 ! pteridine and derivative metabolic process GO:0042558 19 18 0,000 0,01456727 0,02279567 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01456727 0,02278569 GO:0005763|mitochondrial small ribosomal subunit, ! signal complex assembly GO:0007172 18 18 0,000 0,01456727 0,02277571 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 19 18 0,000 0,01456727 0,02276574 ! limbic system development GO:0021761 18 18 0,000 0,01456727 0,02275578 ! cellular response to hydrogen peroxide GO:0070301 18 18 0,000 0,01456727 0,02274583 GO:0042744|hydrogen peroxide catabolic process, ! MHC class II protein complex GO:0042613 18 18 0,000 0,01456727 0,02273589 ! positive regulation of proteolysis GO:0045862 19 18 0,000 0,01456727 0,02272596 ! deoxyribonucleotide metabolic process GO:0009262 19 18 0,000 0,01456727 0,02271603 ! lysosome organization GO:0007040 18 18 0,000 0,01456727 0,02270612 ! central nervous system neuron development GO:0021954 19 18 0,000 0,01456727 0,02269621 ! fatty acid beta-oxidation GO:0006635 18 18 0,000 0,01456727 0,02268631 ! regulation of viral reproduction GO:0050792 18 18 0,000 0,01456727 0,02267643 ! peptide cross-linking GO:0018149 20 18 0,000 0,01456727 0,02266654 ! ventricular cardiac muscle morphogenesis GO:0055010 19 18 0,000 0,01456727 0,02265667 ! presynaptic membrane GO:0042734 19 18 0,000 0,01456727 0,02264681 ! embryonic digit morphogenesis GO:0042733 20 18 0,000 0,01456727 0,02263695 ! neural crest cell migration GO:0001755 18 18 0,000 0,01456727 0,02262711 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01456727 0,02261727 ! positive regulation of adaptive immune response GO:0002821 22 18 0,000 0,01456727 0,02260744 ! positive regulation of intracellular transport GO:0032388 19 18 0,000 0,01456727 0,02259762 ! negative regulation of intracellular transport GO:0032387 18 18 0,000 0,01456727 0,02258781 ! peptidyl-serine modification GO:0018209 18 18 0,000 0,01456727 0,022578 ! cell-cell recognition GO:0009988 19 18 0,000 0,01456727 0,02256821 ! vitamin D receptor binding GO:0042809 19 18 0,000 0,01456727 0,02255842 ! porphyrin biosynthetic process GO:0006779 18 18 0,000 0,01456727 0,02254864 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 18 0,000 0,01456727 0,02253887 ! actin filament-based movement GO:0030048 18 18 0,000 0,01456727 0,02252911 ! Rab GTPase binding GO:0017137 18 18 0,000 0,01456727 0,02251936 ! protein import into nucleus, docking GO:0000059 18 18 0,000 0,01456727 0,02250961 ! negative regulation of cell cycle process GO:0010948 18 18 0,000 0,01456727 0,02249988 ! glycerol metabolic process GO:0006071 19 18 0,000 0,01456727 0,02249015 ! post-Golgi vesicle-mediated transport GO:0006892 18 18 0,000 0,01456727 0,02248043 ! intra-Golgi vesicle-mediated transport GO:0006891 18 18 0,000 0,01456727 0,02247072 ! aminoglycan catabolic process GO:0006026 18 18 0,000 0,01456727 0,02246102 ! aminoglycan biosynthetic process GO:0006023 18 18 0,000 0,01456727 0,02245132 ! small conjugating protein binding GO:0032182 18 18 0,000 0,01456727 0,02244164 ! memory GO:0007613 19 18 0,000 0,01456727 0,02243196 ! C21-steroid hormone metabolic process GO:0008207 18 18 0,000 0,01456727 0,02242229 ! regulation of DNA recombination GO:0000018 22 18 0,000 0,01456727 0,02241263 ! protein phosphatase type 2A complex GO:0000159 20 18 0,000 0,01456727 0,02240298 ! inactivation of MAPK activity GO:0000188 19 18 0,000 0,01456727 0,02239334 ! pigmentation during development GO:0048066 21 18 0,000 0,01456727 0,0223837 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 18 0,000 0,01456727 0,02237407 ! acetylcholine binding GO:0042166 19 18 0,000 0,01456727 0,02236445 ! neurotransmitter:sodium symporter activity GO:0005328 18 18 0,000 0,01456727 0,02235484 ! neurotransmitter metabolic process GO:0042133 23 18 0,000 0,01456727 0,02234524 ! neuromuscular junction development GO:0007528 21 18 0,000 0,01456727 0,02233565 ! nonmotile primary cilium GO:0031513 19 18 0,000 0,01456727 0,02232606 ! coreceptor activity GO:0015026 18 18 0,000 0,01456727 0,02231648 ! behavioral interaction between organisms GO:0051705 18 18 0,000 0,01456727 0,02230691 ! carbonate dehydratase activity GO:0004089 19 18 0,000 0,01456727 0,02229735 ! cytolysis GO:0019835 18 18 0,000 0,01456727 0,0222878 ! phosphate binding GO:0042301 19 18 0,000 0,01456727 0,02227825 ! transport vesicle membrane GO:0030658 21 18 0,000 0,01456727 0,02226872 ! specific transcriptional repressor activity GO:0016566 18 18 0,000 0,01456727 0,02225919 ! DNA modification GO:0006304 20 18 0,000 0,01456727 0,02224967 ! bicarbonate transmembrane transporter activity GO:0015106 19 18 0,000 0,01456727 0,02224015 ! detection of chemical stimulus GO:0009593 19 18 0,000 0,01456727 0,02223065 ! ionotropic glutamate receptor activity GO:0004970 20 18 0,000 0,01456727 0,02222115 ! aspartic-type endopeptidase activity GO:0004190 19 18 0,000 0,01456727 0,02221167 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 18 18 0,000 0,01456727 0,02220219 ! 3'-5' exonuclease activity GO:0008408 18 18 0,000 0,01456727 0,02219271 ! RNA polymerase II transcription mediator activity GO:0016455 19 18 0,000 0,01456727 0,02218325 ! water-soluble vitamin biosynthetic process GO:0042364 19 18 0,000 0,01456727 0,02217379 ! connexon complex GO:0005922 18 18 0,000 0,01456727 0,02216435 ! solute:hydrogen antiporter activity GO:0015299 18 18 0,000 0,01456727 0,02215491 ! mRNA export from nucleus GO:0006406 21 19 0,000 0,01537083 0,02336706 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 20 19 0,000 0,01537083 0,02335712 ! regulation of interferon-gamma production GO:0032649 20 19 0,000 0,01537083 0,02334719 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 20 19 0,000 0,01537083 0,02333726 ! anion:anion antiporter activity GO:0015301 20 19 0,000 0,01537083 0,02332734 ! cAMP metabolic process GO:0046058 19 19 0,000 0,01537083 0,02331743 ! spindle microtubule GO:0005876 20 19 0,000 0,01537083 0,02330753 ! ovarian follicle development GO:0001541 19 19 0,000 0,01537083 0,02329764 ! retinoid metabolic process GO:0001523 19 19 0,000 0,01537083 0,02328775 GO:0016101|diterpenoid metabolic process, ! caspase activator activity GO:0008656 19 19 0,000 0,01537083 0,02327788 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 21 19 0,000 0,01537083 0,02326801 ! vacuolar transport GO:0007034 19 19 0,000 0,01537083 0,02325815 ! threonine-type endopeptidase activity GO:0004298 19 19 0,000 0,01537083 0,0232483 GO:0070003|threonine-type peptidase activity, ! myofibril assembly GO:0030239 19 19 0,000 0,01537083 0,02323846 GO:0055002|striated muscle cell development, ! monocarboxylic acid transmembrane transporter activity GO:0008028 20 19 0,000 0,01537083 0,02322862 ! positive regulation of multicellular organism growth GO:0040018 19 19 0,000 0,01537083 0,0232188 ! cell projection membrane GO:0031253 20 19 0,000 0,01537083 0,02320898 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01537083 0,02319917 ! transcriptional repressor complex GO:0017053 19 19 0,000 0,01537083 0,02318937 ! vitamin A metabolic process GO:0006776 19 19 0,000 0,01537083 0,02317958 ! positive regulation of myeloid cell differentiation GO:0045639 20 19 0,000 0,01537083 0,02316979 ! negative regulation of myeloid cell differentiation GO:0045638 19 19 0,000 0,01537083 0,02316001 ! glutamine family amino acid catabolic process GO:0009065 21 19 0,000 0,01537083 0,02315025 ! leukotriene biosynthetic process GO:0019370 19 19 0,000 0,01537083 0,02314049 GO:0043450|alkene biosynthetic process, ! gas transport GO:0015669 20 19 0,000 0,01537083 0,02313073 ! retinoid binding GO:0005501 19 19 0,000 0,01537083 0,02312099 GO:0019840|isoprenoid binding, ! peptide hormone secretion GO:0030072 20 19 0,000 0,01537083 0,02311126 ! protein stabilization GO:0050821 20 19 0,000 0,01537083 0,02310153 ! cellular monovalent inorganic cation homeostasis GO:0030004 20 19 0,000 0,01537083 0,02309181 ! myeloid leukocyte differentiation GO:0002573 21 19 0,000 0,01537083 0,0230821 ! microtubule-based transport GO:0010970 19 19 0,000 0,01537083 0,0230724 ! protein complex scaffold GO:0032947 19 19 0,000 0,01537083 0,0230627 ! SNAP receptor activity GO:0005484 21 19 0,000 0,01537083 0,02305302 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01537083 0,02304334 GO:0006479|protein amino acid methylation, ! regulation of systemic arterial blood pressure by hormone GO:0001990 19 19 0,000 0,01537083 0,02303367 GO:0050886|endocrine process, ! visual behavior GO:0007632 22 19 0,000 0,01537083 0,02302401 GO:0008542|visual learning, ! 4 iron, 4 sulfur cluster binding GO:0051539 21 19 0,000 0,01537083 0,02301435 ! glycoprotein binding GO:0001948 23 19 0,000 0,01537083 0,02300471 ! sensory perception of taste GO:0050909 19 19 0,000 0,01537083 0,02299507 ! myoblast differentiation GO:0045445 19 19 0,000 0,01537083 0,02298544 ! cell differentiation in spinal cord GO:0021515 19 19 0,000 0,01537083 0,02297582 ! immune response-activating cell surface receptor signaling pathway GO:0002429 25 19 0,000 0,01537083 0,02296621 ! myosin binding GO:0017022 19 19 0,000 0,01537083 0,0229566 ! organic acid:sodium symporter activity GO:0005343 19 19 0,000 0,01537083 0,022947 ! cell aging GO:0007569 19 19 0,000 0,01537083 0,02293741 ! stem cell differentiation GO:0048863 19 19 0,000 0,01537083 0,02292783 ! regulation of myeloid leukocyte differentiation GO:0002761 21 19 0,000 0,01537083 0,02291826 ! heart process GO:0003015 20 19 0,000 0,01537083 0,0229087 GO:0060047|heart contraction, ! mismatch repair GO:0006298 19 19 0,000 0,01537083 0,02289914 ! secretory granule membrane GO:0030667 20 19 0,000 0,01537083 0,02288959 ! MHC protein binding GO:0042287 19 19 0,000 0,01537083 0,02288005 ! extracellular-glutamate-gated ion channel activity GO:0005234 21 19 0,000 0,01537083 0,02287051 ! chloride transmembrane transporter activity GO:0015108 20 19 0,000 0,01537083 0,02286099 ! GABA-A receptor activity GO:0004890 20 19 0,000 0,01537083 0,02285147 ! response to cytokine stimulus GO:0034097 20 19 0,000 0,01537083 0,02284196 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01537083 0,02283246 ! translation elongation factor activity GO:0003746 22 19 0,000 0,01537083 0,02282297 ! insulin receptor binding GO:0005158 20 19 0,000 0,01537083 0,02281348 ! phosphoprotein phosphatase inhibitor activity GO:0004864 21 19 0,000 0,01537083 0,022804 ! protein secretion GO:0009306 20 20 0,000 0,01617379 0,0239853 ! positive regulation of angiogenesis GO:0045766 22 20 0,000 0,01617379 0,02397534 ! proteasome core complex GO:0005839 20 20 0,000 0,01617379 0,0239654 ! positive regulation of bone remodeling GO:0046852 21 20 0,000 0,01617379 0,02395546 ! heterophilic cell adhesion GO:0007157 21 20 0,000 0,01617379 0,02394552 ! glutathione transferase activity GO:0004364 20 20 0,000 0,01617379 0,0239356 ! microtubule organizing center organization GO:0031023 20 20 0,000 0,01617379 0,02392568 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 20 20 0,000 0,01617379 0,02391578 ! actomyosin GO:0042641 20 20 0,000 0,01617379 0,02390588 ! positive regulation of innate immune response GO:0045089 20 20 0,000 0,01617379 0,02389599 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 20 0,000 0,01617379 0,02388611 ! vacuole organization GO:0007033 20 20 0,000 0,01617379 0,02387623 ! oxidoreductase activity, acting on heme group of donors GO:0016675 21 20 0,000 0,01617379 0,02386636 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! purine ribonucleoside metabolic process GO:0046128 23 20 0,000 0,01617379 0,02385651 GO:0042278|purine nucleoside metabolic process, ! chromosome condensation GO:0030261 20 20 0,000 0,01617379 0,02384666 ! regulation of exocytosis GO:0017157 21 20 0,000 0,01617379 0,02383681 ! vitamin biosynthetic process GO:0009110 21 20 0,000 0,01617379 0,02382698 ! glycosphingolipid metabolic process GO:0006687 20 20 0,000 0,01617379 0,02381716 ! kinase activator activity GO:0019209 20 20 0,000 0,01617379 0,02380734 ! diencephalon development GO:0021536 20 20 0,000 0,01617379 0,02379753 ! synaptic vesicle transport GO:0048489 21 20 0,000 0,01617379 0,02378773 ! proteoglycan biosynthetic process GO:0030166 20 20 0,000 0,01617379 0,02377793 ! negative regulation of Wnt receptor signaling pathway GO:0030178 21 20 0,000 0,01617379 0,02376815 ! leukocyte homeostasis GO:0001776 22 20 0,000 0,01617379 0,02375837 ! positive regulation of osteoblast differentiation GO:0045669 22 20 0,000 0,01617379 0,0237486 ! regulation of generation of precursor metabolites and energy GO:0043467 21 20 0,000 0,01617379 0,02373884 ! ligase activity, forming carbon-sulfur bonds GO:0016877 20 20 0,000 0,01617379 0,02372909 ! phosphorus-oxygen lyase activity GO:0016849 20 20 0,000 0,01617379 0,02371934 ! alditol metabolic process GO:0019400 21 20 0,000 0,01617379 0,02370961 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 20 0,000 0,01617379 0,02369988 ! chromosome, telomeric region GO:0000781 21 20 0,000 0,01617379 0,02369016 ! calcium-independent cell-cell adhesion GO:0016338 20 20 0,000 0,01617379 0,02368044 ! response to alkaloid GO:0043279 22 20 0,000 0,01617379 0,02367074 ! transmembrane receptor protein phosphatase activity GO:0019198 27 20 0,000 0,01617379 0,02366104 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! smooth muscle contraction GO:0006939 21 20 0,000 0,01617379 0,02365135 ! heme metabolic process GO:0042168 22 20 0,000 0,01617379 0,02364167 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0,000 0,01617379 0,023632 ! sex determination GO:0007530 20 20 0,000 0,01617379 0,02362233 ! negative regulation of protein catabolic process GO:0042177 21 20 0,000 0,01617379 0,02361267 ! peptide secretion GO:0002790 21 20 0,000 0,01617379 0,02360303 ! regulation of alpha-beta T cell activation GO:0046634 24 20 0,000 0,01617379 0,02359338 ! interaction with host GO:0051701 24 20 0,000 0,01617379 0,02358375 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 26 20 0,000 0,01617379 0,02357412 ! vasodilation GO:0042311 21 20 0,000 0,01617379 0,02356451 ! regulation of tumor necrosis factor production GO:0032680 20 20 0,000 0,01617379 0,02355489 ! regulation of chromosome organization GO:0033044 20 20 0,000 0,01617379 0,02354529 ! inward rectifier potassium channel activity GO:0005242 20 20 0,000 0,01617379 0,0235357 ! activation of JUN kinase activity GO:0007257 20 20 0,000 0,01617379 0,02352611 ! cyclic nucleotide binding GO:0030551 22 20 0,000 0,01617379 0,02351653 ! somatic diversification of immunoglobulins GO:0016445 20 20 0,000 0,01617379 0,02350696 ! microvillus GO:0005902 20 20 0,000 0,01617379 0,0234974 ! tumor necrosis factor receptor binding GO:0005164 20 20 0,000 0,01617379 0,02348784 ! ATP-dependent RNA helicase activity GO:0004004 20 20 0,000 0,01617379 0,02347829 ! positive regulation of protein catabolic process GO:0045732 22 21 0,000 0,01697615 0,02463301 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 22 21 0,000 0,01697615 0,024623 ! growth cone GO:0030426 22 21 0,000 0,01697615 0,024613 ! oligosaccharide metabolic process GO:0009311 23 21 0,000 0,01697615 0,02460301 ! regulation of anti-apoptosis GO:0045767 21 21 0,000 0,01697615 0,02459303 ! hormone secretion GO:0046879 22 21 0,000 0,01697615 0,02458306 ! protein amino acid O-linked glycosylation GO:0006493 22 21 0,000 0,01697615 0,0245731 ! transition metal ion transmembrane transporter activity GO:0046915 21 21 0,000 0,01697615 0,02456314 ! voltage-gated calcium channel complex GO:0005891 24 21 0,000 0,01697615 0,02455319 GO:0034704|calcium channel complex, ! dicarboxylic acid metabolic process GO:0043648 22 21 0,000 0,01697615 0,02454325 ! protein phosphatase type 2A regulator activity GO:0008601 23 21 0,000 0,01697615 0,02453332 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 24 21 0,000 0,01697615 0,02452339 ! histone-lysine N-methyltransferase activity GO:0018024 23 21 0,000 0,01697615 0,02451348 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! activation of pro-apoptotic gene products GO:0008633 22 21 0,000 0,01697615 0,02450357 ! mitochondrial membrane organization GO:0007006 22 21 0,000 0,01697615 0,02449367 ! central nervous system neuron differentiation GO:0021953 22 21 0,000 0,01697615 0,02448378 ! Golgi stack GO:0005795 25 21 0,000 0,01697615 0,02447389 ! muscle cell development GO:0055001 21 21 0,000 0,01697615 0,02446401 ! cholesterol biosynthetic process GO:0006695 22 21 0,000 0,01697615 0,02445415 ! regulation of vasoconstriction GO:0019229 22 21 0,000 0,01697615 0,02444429 ! phosphatase inhibitor activity GO:0019212 23 21 0,000 0,01697615 0,02443443 ! regulation of fatty acid metabolic process GO:0019217 22 21 0,000 0,01697615 0,02442459 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,01697615 0,02441475 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! sensory perception of pain GO:0019233 21 21 0,000 0,01697615 0,02440492 ! pentose metabolic process GO:0019321 22 21 0,000 0,01697615 0,0243951 ! platelet activation GO:0030168 23 21 0,000 0,01697615 0,02438529 ! response to glucocorticoid stimulus GO:0051384 22 21 0,000 0,01697615 0,02437548 ! trans-Golgi network transport vesicle GO:0030140 24 21 0,000 0,01697615 0,02436569 ! glutathione metabolic process GO:0006749 21 21 0,000 0,01697615 0,0243559 ! DNA-directed RNA polymerase complex GO:0000428 22 21 0,000 0,01697615 0,02434612 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! terpenoid metabolic process GO:0006721 21 21 0,000 0,01697615 0,02433634 ! cyclase activity GO:0009975 21 21 0,000 0,01697615 0,02432658 ! intramolecular transferase activity GO:0016866 22 21 0,000 0,01697615 0,02431682 ! negative regulation of cytokine production GO:0001818 21 21 0,000 0,01697615 0,02430707 ! fatty acid binding GO:0005504 21 21 0,000 0,01697615 0,02429733 ! gut development GO:0048565 21 21 0,000 0,01697615 0,02428759 ! acetyl-CoA catabolic process GO:0046356 21 21 0,000 0,01697615 0,02427786 GO:0006099|tricarboxylic acid cycle, ! phosphoinositide phospholipase C activity GO:0004435 21 21 0,000 0,01697615 0,02426815 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! protein tetramerization GO:0051262 22 21 0,000 0,01697615 0,02425843 ! regulation of microtubule polymerization or depolymerization GO:0031110 23 21 0,000 0,01697615 0,02424873 ! voltage-gated anion channel activity GO:0008308 21 21 0,000 0,01697615 0,02423904 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,01697615 0,02422935 ! cellular polysaccharide biosynthetic process GO:0033692 21 21 0,000 0,01697615 0,02421967 ! positive regulation of JAK-STAT cascade GO:0046427 22 21 0,000 0,01697615 0,02420999 ! sterol binding GO:0032934 21 21 0,000 0,01697615 0,02420033 ! regulation of carbohydrate metabolic process GO:0006109 22 21 0,000 0,01697615 0,02419067 GO:0010675|regulation of cellular carbohydrate metabolic process, ! superoxide metabolic process GO:0006801 21 21 0,000 0,01697615 0,02418102 ! calcium-dependent cell-cell adhesion GO:0016339 21 21 0,000 0,01697615 0,02417138 ! phosphatase binding GO:0019902 22 21 0,000 0,01697615 0,02416175 ! NAD+ ADP-ribosyltransferase activity GO:0003950 21 21 0,000 0,01697615 0,02415212 ! positive regulation of cytoskeleton organization GO:0051495 21 21 0,000 0,01697615 0,0241425 ! negative regulation of DNA replication GO:0008156 25 21 0,000 0,01697615 0,02413289 ! vesicle targeting GO:0006903 22 21 0,000 0,01697615 0,02412329 ! vesicle docking during exocytosis GO:0006904 21 21 0,000 0,01697615 0,02411369 ! cell structure disassembly during apoptosis GO:0006921 21 21 0,000 0,01697615 0,02410411 ! RNA-dependent ATPase activity GO:0008186 21 21 0,000 0,01697615 0,02409453 ! renal system process GO:0003014 22 21 0,000 0,01697615 0,02408495 ! positive regulation of leukocyte mediated immunity GO:0002705 25 21 0,000 0,01697615 0,02407539 GO:0002708|positive regulation of lymphocyte mediated immunity, ! nuclear-transcribed mRNA catabolic process GO:0000956 22 21 0,000 0,01697615 0,02406583 ! apoptotic protease activator activity GO:0016505 21 21 0,000 0,01697615 0,02405628 ! fatty acid transport GO:0015908 21 21 0,000 0,01697615 0,02404674 ! sarcoplasmic reticulum GO:0016529 22 21 0,000 0,01697615 0,0240372 ! positive regulation of tissue remodeling GO:0034105 22 21 0,000 0,01697615 0,02402768 ! collagen catabolic process GO:0030574 21 21 0,000 0,01697615 0,02401816 ! pyrimidine nucleotide biosynthetic process GO:0006221 25 21 0,000 0,01697615 0,02400864 ! regulation of multi-organism process GO:0043900 21 21 0,000 0,01697615 0,02399914 ! ubiquitin-specific protease activity GO:0004843 22 21 0,000 0,01697615 0,02398964 ! site of polarized growth GO:0030427 23 22 0,000 0,01777791 0,0251127 ! leukocyte adhesion GO:0007159 27 22 0,000 0,01777791 0,02510277 ! glutamate signaling pathway GO:0007215 25 22 0,000 0,01777791 0,02509285 ! potassium channel regulator activity GO:0015459 24 22 0,000 0,01777791 0,02508294 ! peroxisome organization GO:0007031 22 22 0,000 0,01777791 0,02507303 ! cellular response to reactive oxygen species GO:0034614 22 22 0,000 0,01777791 0,02506313 ! polysaccharide catabolic process GO:0000272 22 22 0,000 0,01777791 0,02505324 ! response to starvation GO:0042594 23 22 0,000 0,01777791 0,02504336 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 22 22 0,000 0,01777791 0,02503348 ! coenzyme catabolic process GO:0009109 22 22 0,000 0,01777791 0,02502361 ! regulation of insulin secretion GO:0050796 23 22 0,000 0,01777791 0,02501375 ! membrane depolarization GO:0051899 24 22 0,000 0,01777791 0,0250039 ! somitogenesis GO:0001756 23 22 0,000 0,01777791 0,02499406 ! regulation of cytokine secretion GO:0050707 22 22 0,000 0,01777791 0,02498422 ! natural killer cell activation GO:0030101 22 22 0,000 0,01777791 0,02497439 ! positive regulation of B cell activation GO:0050871 26 22 0,000 0,01777791 0,02496457 ! aromatic amino acid family metabolic process GO:0009072 25 22 0,000 0,01777791 0,02495476 ! basal plasma membrane GO:0009925 22 22 0,000 0,01777791 0,02494495 GO:0045178|basal part of cell, ! telomere organization GO:0032200 23 22 0,000 0,01777791 0,02493516 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 24 22 0,000 0,01777791 0,02492537 GO:0060606|tube closure, ! response to molecule of bacterial origin GO:0002237 22 22 0,000 0,01777791 0,02491558 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 22 0,000 0,01777791 0,02490581 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 22 22 0,000 0,01777791 0,02489604 GO:0016444|somatic cell DNA recombination, ! cortical actin cytoskeleton GO:0030864 22 22 0,000 0,01777791 0,02488628 ! initiation of viral infection GO:0019059 22 22 0,000 0,01777791 0,02487653 ! RNA polymerase complex GO:0030880 23 22 0,000 0,01777791 0,02486679 ! regulation of neurotransmitter transport GO:0051588 23 22 0,000 0,01777791 0,02485705 ! macromolecular complex disassembly GO:0032984 23 22 0,000 0,01777791 0,02484732 ! response to ethanol GO:0045471 25 22 0,000 0,01777791 0,0248376 ! syntaxin binding GO:0019905 23 22 0,000 0,01777791 0,02482789 ! regulation of nitric oxide biosynthetic process GO:0045428 22 22 0,000 0,01777791 0,02481818 ! digestive system process GO:0022600 24 22 0,000 0,01777791 0,02480848 ! neurotransmitter transporter activity GO:0005326 22 22 0,000 0,01777791 0,02479879 ! autophagy GO:0006914 24 22 0,000 0,01777791 0,02478911 ! carbohydrate kinase activity GO:0019200 22 22 0,000 0,01777791 0,02477943 ! neuropeptide hormone activity GO:0005184 23 22 0,000 0,01777791 0,02476977 ! negative regulation of phosphorylation GO:0042326 26 22 0,000 0,01777791 0,02476011 ! transaminase activity GO:0008483 23 22 0,000 0,01777791 0,02475045 ! sarcoplasm GO:0016528 23 22 0,000 0,01777791 0,02474081 ! metallocarboxypeptidase activity GO:0004181 23 22 0,000 0,01777791 0,02473117 ! cellular response to nutrient levels GO:0031669 23 22 0,000 0,01777791 0,02472154 ! positive regulation of nuclear division GO:0051785 22 22 0,000 0,01777791 0,02471192 GO:0045840|positive regulation of mitosis, ! nerve-nerve synaptic transmission GO:0007270 25 22 0,000 0,01777791 0,0247023 ! small conjugating protein-specific protease activity GO:0019783 24 22 0,000 0,01777791 0,02469269 ! pyrimidine nucleoside metabolic process GO:0006213 25 22 0,000 0,01777791 0,02468309 ! solute:cation antiporter activity GO:0015298 22 22 0,000 0,01777791 0,0246735 ! translational initiation GO:0006413 23 23 0,000 0,01857907 0,02577539 ! NF-kappaB binding GO:0051059 23 23 0,000 0,01857907 0,02576538 ! vesicle docking GO:0048278 23 23 0,000 0,01857907 0,02575538 ! muscle myosin complex GO:0005859 25 23 0,000 0,01857907 0,02574538 ! vasculogenesis GO:0001570 25 23 0,000 0,01857907 0,0257354 ! regulation of innate immune response GO:0045088 23 23 0,000 0,01857907 0,02572542 ! androgen receptor binding GO:0050681 23 23 0,000 0,01857907 0,02571545 ! positive regulation of epithelial cell proliferation GO:0050679 24 23 0,000 0,01857907 0,02570548 ! sperm motility GO:0030317 23 23 0,000 0,01857907 0,02569553 ! apoptotic nuclear changes GO:0030262 23 23 0,000 0,01857907 0,02568558 ! barbed-end actin filament capping GO:0051016 23 23 0,000 0,01857907 0,02567564 GO:0051693|actin filament capping, ! negative regulation of phosphorus metabolic process GO:0010563 27 23 0,000 0,01857907 0,02566571 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 24 23 0,000 0,01857907 0,02565578 ! cardiac muscle tissue morphogenesis GO:0055008 24 23 0,000 0,01857907 0,02564586 GO:0060415|muscle tissue morphogenesis, ! cyclic nucleotide biosynthetic process GO:0009190 23 23 0,000 0,01857907 0,02563596 ! leukotriene metabolic process GO:0006691 23 23 0,000 0,01857907 0,02562605 ! positive regulation of T cell differentiation GO:0045582 27 23 0,000 0,01857907 0,02561616 ! glycolipid metabolic process GO:0006664 23 23 0,000 0,01857907 0,02560627 ! regulation of ARF GTPase activity GO:0032312 26 23 0,000 0,01857907 0,02559639 ! pallium development GO:0021543 23 23 0,000 0,01857907 0,02558652 ! GABA receptor activity GO:0016917 24 23 0,000 0,01857907 0,02557666 ! positive regulation of MAPKKK cascade GO:0043410 30 23 0,000 0,01857907 0,0255668 ! regulation of response to biotic stimulus GO:0002831 23 23 0,000 0,01857907 0,02555695 ! MHC class II receptor activity GO:0032395 23 23 0,000 0,01857907 0,02554711 ! nicotinamide metabolic process GO:0006769 23 23 0,000 0,01857907 0,02553728 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of neuron differentiation GO:0045665 23 23 0,000 0,01857907 0,02552745 ! aspartate family amino acid metabolic process GO:0009066 24 23 0,000 0,01857907 0,02551764 ! insulin-like growth factor binding GO:0005520 23 23 0,000 0,01857907 0,02550782 ! regulation of amine transport GO:0051952 23 23 0,000 0,01857907 0,02549802 ! tissue homeostasis GO:0001894 24 23 0,000 0,01857907 0,02548823 GO:0048871|multicellular organismal homeostasis, ! protein import into nucleus, translocation GO:0000060 25 23 0,000 0,01857907 0,02547844 ! gluconeogenesis GO:0006094 24 23 0,000 0,01857907 0,02546866 ! iron ion transport GO:0006826 24 23 0,000 0,01857907 0,02545888 ! nucleotide-excision repair, DNA damage removal GO:0000718 24 23 0,000 0,01857907 0,02544912 ! N-acetylglucosamine metabolic process GO:0006044 23 23 0,000 0,01857907 0,02543936 ! molting cycle process GO:0022404 23 23 0,000 0,01857907 0,02542961 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! circadian rhythm GO:0007623 24 23 0,000 0,01857907 0,02541987 ! tube lumen formation GO:0035148 26 23 0,000 0,01857907 0,02541013 ! insulin receptor signaling pathway GO:0008286 28 23 0,000 0,01857907 0,0254004 ! multicellular organismal response to stress GO:0033555 23 23 0,000 0,01857907 0,02539068 ! immune response-activating signal transduction GO:0002757 29 23 0,000 0,01857907 0,02538097 ! lymphocyte proliferation GO:0046651 29 23 0,000 0,01857907 0,02537126 ! fibroblast growth factor receptor signaling pathway GO:0008543 24 23 0,000 0,01857907 0,02536156 ! regulation of bone mineralization GO:0030500 25 23 0,000 0,01857907 0,02535187 ! single-stranded RNA binding GO:0003727 24 23 0,000 0,01857907 0,02534219 ! brush border GO:0005903 25 23 0,000 0,01857907 0,02533251 ! caveola GO:0005901 24 23 0,000 0,01857907 0,02532284 ! gap junction GO:0005921 23 23 0,000 0,01857907 0,02531318 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 25 24 0,000 0,01937963 0,02639384 ! regulation of transmembrane transport GO:0034762 24 24 0,000 0,01937963 0,02638378 ! heterotrimeric G-protein complex GO:0005834 24 24 0,000 0,01937963 0,02637373 ! protein amino acid acylation GO:0043543 26 24 0,000 0,01937963 0,02636368 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 24 0,000 0,01937963 0,02635364 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 25 24 0,000 0,01937963 0,02634361 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,01937963 0,02633358 ! MHC class I protein complex GO:0042612 24 24 0,000 0,01937963 0,02632357 ! G-protein chemoattractant receptor activity GO:0001637 24 24 0,000 0,01937963 0,02631356 GO:0004950|chemokine receptor activity, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 24 24 0,000 0,01937963 0,02630356 ! early endosome membrane GO:0031901 26 24 0,000 0,01937963 0,02629356 ! primary neural tube formation GO:0014020 26 24 0,000 0,01937963 0,02628358 ! ARF GTPase activator activity GO:0008060 27 24 0,000 0,01937963 0,0262736 ! hydrogen peroxide metabolic process GO:0042743 24 24 0,000 0,01937963 0,02626363 ! immunoglobulin production GO:0002377 28 24 0,000 0,01937963 0,02625366 GO:0002440|production of molecular mediator of immune response, ! lipid kinase activity GO:0001727 26 24 0,000 0,01937963 0,02624371 ! positive regulation of protein secretion GO:0050714 26 24 0,000 0,01937963 0,02623376 ! MHC class I receptor activity GO:0032393 24 24 0,000 0,01937963 0,02622382 ! RNA splicing factor activity, transesterification mechanism GO:0031202 24 24 0,000 0,01937963 0,02621388 ! fat-soluble vitamin metabolic process GO:0006775 24 24 0,000 0,01937963 0,02620396 ! regulation of osteoblast differentiation GO:0045667 27 24 0,000 0,01937963 0,02619404 ! cellular alkene metabolic process GO:0043449 24 24 0,000 0,01937963 0,02618413 ! somatic diversification of immune receptors GO:0002200 24 24 0,000 0,01937963 0,02617423 ! positive regulation of JUN kinase activity GO:0043507 24 24 0,000 0,01937963 0,02616433 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 26 24 0,000 0,01937963 0,02615444 ! Z disc GO:0030018 27 24 0,000 0,01937963 0,02614456 ! negative regulation of lymphocyte activation GO:0051250 24 24 0,000 0,01937963 0,02613469 ! alkaloid metabolic process GO:0009820 24 24 0,000 0,01937963 0,02612482 ! neuron fate commitment GO:0048663 24 24 0,000 0,01937963 0,02611496 ! DNA catabolic process, endonucleolytic GO:0000737 24 24 0,000 0,01937963 0,02610511 ! glucosamine metabolic process GO:0006041 24 24 0,000 0,01937963 0,02609527 ! regulation of transcription factor import into nucleus GO:0042990 25 24 0,000 0,01937963 0,02608543 ! glucose transport GO:0015758 24 24 0,000 0,01937963 0,0260756 ! dendrite development GO:0016358 26 24 0,000 0,01937963 0,02606578 ! catechol metabolic process GO:0009712 27 24 0,000 0,01937963 0,02605597 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phospholipase A2 activity GO:0004623 26 24 0,000 0,01937963 0,02604616 ! immune response-regulating signal transduction GO:0002764 30 24 0,000 0,01937963 0,02603636 ! regulation of production of molecular mediator of immune response GO:0002700 28 24 0,000 0,01937963 0,02602657 ! DNA-directed DNA polymerase activity GO:0003887 25 24 0,000 0,01937963 0,02601679 ! synaptogenesis GO:0007416 25 24 0,000 0,01937963 0,02600701 ! selenium binding GO:0008430 24 24 0,000 0,01937963 0,02599724 ! leukocyte proliferation GO:0070661 30 24 0,000 0,01937963 0,02598748 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 26 24 0,000 0,01937963 0,02597772 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 25 25 0,000 0,02017959 0,0270399 ! phenol metabolic process GO:0018958 28 25 0,000 0,02017959 0,02702975 ! myelination GO:0042552 26 25 0,000 0,02017959 0,02701962 ! epidermal growth factor receptor signaling pathway GO:0007173 28 25 0,000 0,02017959 0,02700949 ! hexose transport GO:0008645 25 25 0,000 0,02017959 0,02699937 GO:0015749|monosaccharide transport, ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 27 25 0,000 0,02017959 0,02698926 ! PML body GO:0016605 28 25 0,000 0,02017959 0,02697915 ! regulation of cellular ketone metabolic process GO:0010565 26 25 0,000 0,02017959 0,02696906 ! negative regulation of cell development GO:0010721 28 25 0,000 0,02017959 0,02695897 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 27 25 0,000 0,02017959 0,02694889 ! cell fate determination GO:0001709 25 25 0,000 0,02017959 0,02693881 ! regulation of oxidoreductase activity GO:0051341 25 25 0,000 0,02017959 0,02692874 ! group transfer coenzyme metabolic process GO:0006752 26 25 0,000 0,02017959 0,02691869 ! hormone transport GO:0009914 26 25 0,000 0,02017959 0,02690863 ! neuromuscular process controlling balance GO:0050885 26 25 0,000 0,02017959 0,02689859 ! porphyrin metabolic process GO:0006778 27 25 0,000 0,02017959 0,02688855 GO:0033013|tetrapyrrole metabolic process, ! regulation of JUN kinase activity GO:0043506 25 25 0,000 0,02017959 0,02687852 ! cell adhesion molecule binding GO:0050839 27 25 0,000 0,02017959 0,0268685 ! negative regulation of actin filament depolymerization GO:0030835 25 25 0,000 0,02017959 0,02685849 ! acetyl-CoA metabolic process GO:0006084 25 25 0,000 0,02017959 0,02684848 ! membrane lipid catabolic process GO:0046466 26 25 0,000 0,02017959 0,02683848 ! zinc ion transport GO:0006829 26 25 0,000 0,02017959 0,02682849 ! cellular iron ion homeostasis GO:0006879 25 25 0,000 0,02017959 0,0268185 ! phototransduction GO:0007602 25 25 0,000 0,02017959 0,02680853 ! keratinization GO:0031424 26 25 0,000 0,02017959 0,02679856 ! spinal cord development GO:0021510 25 25 0,000 0,02017959 0,02678859 ! cyclin-dependent protein kinase activity GO:0004693 26 25 0,000 0,02017959 0,02677864 ! regulation of smooth muscle contraction GO:0006940 28 25 0,000 0,02017959 0,02676869 ! response to toxin GO:0009636 25 25 0,000 0,02017959 0,02675875 ! regulation of peptide secretion GO:0002791 26 25 0,000 0,02017959 0,02674882 ! determination of left/right symmetry GO:0007368 25 25 0,000 0,02017959 0,02673889 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 25 0,000 0,02017959 0,02672898 ! regulation of interleukin-6 production GO:0032675 25 25 0,000 0,02017959 0,02671907 ! voltage-gated calcium channel activity GO:0005245 28 25 0,000 0,02017959 0,02670916 ! phospholipid transport GO:0015914 26 25 0,000 0,02017959 0,02669927 ! peptidase activator activity GO:0016504 25 25 0,000 0,02017959 0,02668938 ! protein localization in mitochondrion GO:0070585 26 25 0,000 0,02017959 0,0266795 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 25 25 0,000 0,02017959 0,02666962 ! regulation of microtubule cytoskeleton organization GO:0070507 27 25 0,000 0,02017959 0,02665976 ! ethanolamine and derivative metabolic process GO:0042439 28 25 0,000 0,02017959 0,0266499 ! small nuclear ribonucleoprotein complex GO:0030532 25 25 0,000 0,02017959 0,02664004 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 25 25 0,000 0,02017959 0,0266302 ! negative regulation of transcription regulator activity GO:0090048 26 25 0,000 0,02017959 0,02662036 GO:0043433|negative regulation of transcription factor activity, ! acetylgalactosaminyltransferase activity GO:0008376 27 25 0,000 0,02017959 0,02661053 ! solute:solute antiporter activity GO:0015300 26 26 0,000 0,02097896 0,02765443 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 27 26 0,000 0,02097896 0,02764422 ! regeneration GO:0031099 26 26 0,000 0,02097896 0,02763403 ! cholesterol homeostasis GO:0042632 26 26 0,000 0,02097896 0,02762384 GO:0055092|sterol homeostasis, ! peptidyl-tyrosine phosphorylation GO:0018108 27 26 0,000 0,02097896 0,02761366 ! ureteric bud development GO:0001657 26 26 0,000 0,02097896 0,02760348 ! neural crest cell development GO:0014032 26 26 0,000 0,02097896 0,02759331 GO:0014033|neural crest cell differentiation, ! negative regulation of protein kinase cascade GO:0010741 27 26 0,000 0,02097896 0,02758316 ! cellular response to oxidative stress GO:0034599 26 26 0,000 0,02097896 0,027573 ! lipid oxidation GO:0034440 26 26 0,000 0,02097896 0,02756286 GO:0019395|fatty acid oxidation, ! positive regulation of lymphocyte differentiation GO:0045621 30 26 0,000 0,02097896 0,02755272 ! pyridine nucleotide metabolic process GO:0019362 26 26 0,000 0,02097896 0,02754259 ! carboxy-lyase activity GO:0016831 26 26 0,000 0,02097896 0,02753247 ! myeloid leukocyte activation GO:0002274 27 26 0,000 0,02097896 0,02752235 ! negative regulation of neuron apoptosis GO:0043524 26 26 0,000 0,02097896 0,02751225 ! negative regulation of catabolic process GO:0009895 28 26 0,000 0,02097896 0,02750215 ! regulation of actin filament depolymerization GO:0030834 26 26 0,000 0,02097896 0,02749205 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02097896 0,02748197 ! determination of bilateral symmetry GO:0009855 26 26 0,000 0,02097896 0,02747189 GO:0009799|determination of symmetry, ! regulation of cellular catabolic process GO:0031329 28 26 0,000 0,02097896 0,02746182 ! pyruvate metabolic process GO:0006090 27 26 0,000 0,02097896 0,02745176 ! cellular component assembly involved in morphogenesis GO:0010927 26 26 0,000 0,02097896 0,0274417 ! histone methyltransferase activity GO:0042054 29 26 0,000 0,02097896 0,02743165 ! chemokine binding GO:0019956 26 26 0,000 0,02097896 0,02742161 ! receptor metabolic process GO:0043112 28 26 0,000 0,02097896 0,02741158 ! nucleotide kinase activity GO:0019201 30 26 0,000 0,02097896 0,02740155 ! phospholipase C activity GO:0004629 27 26 0,000 0,02097896 0,02739154 ! cellular response to extracellular stimulus GO:0031668 27 26 0,000 0,02097896 0,02738152 ! negative regulation of leukocyte activation GO:0002695 26 26 0,000 0,02097896 0,02737152 ! receptor regulator activity GO:0030545 26 26 0,000 0,02097896 0,02736152 ! galactosyltransferase activity GO:0008378 27 26 0,000 0,02097896 0,02735153 ! response to heat GO:0009408 26 26 0,000 0,02097896 0,02734155 ! positive regulation of immune effector process GO:0002699 30 26 0,000 0,02097896 0,02733158 ! mRNA catabolic process GO:0006402 28 27 0,000 0,02177772 0,02836187 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 28 27 0,000 0,02177772 0,02835153 ! actomyosin structure organization GO:0031032 28 27 0,000 0,02177772 0,0283412 ! nucleotide receptor activity, G-protein coupled GO:0001608 27 27 0,000 0,02177772 0,02833087 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 28 27 0,000 0,02177772 0,02832055 ! iron ion homeostasis GO:0055072 27 27 0,000 0,02177772 0,02831025 ! lipoprotein binding GO:0008034 29 27 0,000 0,02177772 0,02829994 ! deaminase activity GO:0019239 27 27 0,000 0,02177772 0,02828965 ! mesoderm formation GO:0001707 28 27 0,000 0,02177772 0,02827936 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 27 27 0,000 0,02177772 0,02826908 ! phospholipid transporter activity GO:0005548 29 27 0,000 0,02177772 0,02825881 ! neural tube formation GO:0001841 29 27 0,000 0,02177772 0,02824854 ! mitotic sister chromatid segregation GO:0000070 27 27 0,000 0,02177772 0,02823829 ! regulation of smooth muscle cell proliferation GO:0048660 27 27 0,000 0,02177772 0,02822804 ! integrin complex GO:0008305 28 27 0,000 0,02177772 0,0282178 ! nuclear chromatin GO:0000790 28 27 0,000 0,02177772 0,02820756 ! post-embryonic development GO:0009791 29 27 0,000 0,02177772 0,02819733 ! antigen processing and presentation of peptide antigen GO:0048002 28 27 0,000 0,02177772 0,02818711 ! ovulation cycle process GO:0022602 27 27 0,000 0,02177772 0,0281769 ! SNARE binding GO:0000149 28 27 0,000 0,02177772 0,02816669 ! biogenic amine biosynthetic process GO:0042401 28 27 0,000 0,02177772 0,0281565 ! spindle pole GO:0000922 28 27 0,000 0,02177772 0,02814631 ! anion:cation symporter activity GO:0015296 28 27 0,000 0,02177772 0,02813612 ! trans-Golgi network GO:0005802 29 28 0,000 0,02257589 0,02915678 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 28 0,000 0,02257589 0,02914624 ! cholesterol transport GO:0030301 28 28 0,000 0,02257589 0,02913571 GO:0015918|sterol transport, ! thyroid hormone receptor binding GO:0046966 29 28 0,000 0,02257589 0,02912518 ! dynein complex GO:0030286 29 28 0,000 0,02257589 0,02911466 ! formation of primary germ layer GO:0001704 29 28 0,000 0,02257589 0,02910415 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 30 28 0,000 0,02257589 0,02909365 ! ovulation cycle GO:0042698 28 28 0,000 0,02257589 0,02908315 ! peptidyl-tyrosine modification GO:0018212 29 28 0,000 0,02257589 0,02907267 ! cofactor catabolic process GO:0051187 30 28 0,000 0,02257589 0,02906219 ! DNA damage checkpoint GO:0000077 31 28 0,000 0,02257589 0,02905171 ! negative regulation of actin filament polymerization GO:0030837 28 28 0,000 0,02257589 0,02904125 ! cortical cytoskeleton GO:0030863 29 28 0,000 0,02257589 0,02903079 ! icosanoid biosynthetic process GO:0046456 29 28 0,000 0,02257589 0,02902034 ! amino sugar metabolic process GO:0006040 28 28 0,000 0,02257589 0,0290099 ! membrane docking GO:0022406 28 28 0,000 0,02257589 0,02899946 ! sister chromatid segregation GO:0000819 28 28 0,000 0,02257589 0,02898903 ! detection of light stimulus involved in sensory perception GO:0050962 28 28 0,000 0,02257589 0,02897861 GO:0050908|detection of light stimulus involved in visual perception, ! cell junction assembly GO:0034329 30 28 0,000 0,02257589 0,0289682 ! complement activation, classical pathway GO:0006958 31 28 0,000 0,02257589 0,0289578 ! multicellular organismal catabolic process GO:0044243 28 28 0,000 0,02257589 0,0289474 ! caspase regulator activity GO:0043028 28 28 0,000 0,02257589 0,02893701 ! ensheathment of neurons GO:0007272 29 28 0,000 0,02257589 0,02892662 GO:0008366|axon ensheathment, ! DNA polymerase activity GO:0034061 29 28 0,000 0,02257589 0,02891625 ! calcium-mediated signaling GO:0019722 28 28 0,000 0,02257589 0,02890588 ! neurotransmitter secretion GO:0007269 29 28 0,000 0,02257589 0,02889552 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 28 28 0,000 0,02257589 0,02888517 ! glycogen metabolic process GO:0005977 29 28 0,000 0,02257589 0,02887482 ! RNA helicase activity GO:0003724 28 28 0,000 0,02257589 0,02886448 ! Rho GTPase activator activity GO:0005100 32 28 0,000 0,02257589 0,02885415 ! symbiosis, encompassing mutualism through parasitism GO:0044403 32 28 0,000 0,02257589 0,02884383 ! transferase activity, transferring nitrogenous groups GO:0016769 30 29 0,000 0,02337346 0,02985216 ! spliceosomal snRNP biogenesis GO:0000387 30 29 0,000 0,02337346 0,02984148 ! odontogenesis of dentine-containing tooth GO:0042475 30 29 0,000 0,02337346 0,02983082 ! scavenger receptor activity GO:0005044 30 29 0,000 0,02337346 0,02982016 ! spindle organization GO:0007051 30 29 0,000 0,02337346 0,02980951 ! mesoderm morphogenesis GO:0048332 30 29 0,000 0,02337346 0,02979887 ! male gonad development GO:0008584 29 29 0,000 0,02337346 0,02978823 ! response to organic cyclic substance GO:0014070 31 29 0,000 0,02337346 0,02977761 ! negative regulation of MAP kinase activity GO:0043407 30 29 0,000 0,02337346 0,02976699 ! sterol biosynthetic process GO:0016126 30 29 0,000 0,02337346 0,02975638 ! endocytic vesicle GO:0030139 29 29 0,000 0,02337346 0,02974577 ! Rho GTPase binding GO:0017048 32 29 0,000 0,02337346 0,02973517 ! fatty acid catabolic process GO:0009062 30 29 0,000 0,02337346 0,02972458 ! regulation of calcium ion transport GO:0051924 32 29 0,000 0,02337346 0,029714 ! negative regulation of protein polymerization GO:0032272 29 29 0,000 0,02337346 0,02970343 ! glucan metabolic process GO:0044042 30 29 0,000 0,02337346 0,02969286 GO:0006073|cellular glucan metabolic process, ! regulation of synaptic plasticity GO:0048167 29 29 0,000 0,02337346 0,0296823 ! proteoglycan metabolic process GO:0006029 30 29 0,000 0,02337346 0,02967175 ! xenobiotic metabolic process GO:0006805 29 29 0,000 0,02337346 0,02966121 ! negative regulation of response to external stimulus GO:0032102 29 29 0,000 0,02337346 0,02965067 ! positive regulation of T cell proliferation GO:0042102 33 29 0,000 0,02337346 0,02964014 ! steroid dehydrogenase activity GO:0016229 29 29 0,000 0,02337346 0,02962962 ! regulation of protein import into nucleus GO:0042306 30 29 0,000 0,02337346 0,0296191 ! clathrin coated vesicle membrane GO:0030665 32 29 0,000 0,02337346 0,0296086 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 30 29 0,000 0,02337346 0,0295981 ! cytosolic small ribosomal subunit GO:0022627 29 29 0,000 0,02337346 0,0295876 ! detection of visible light GO:0009584 29 29 0,000 0,02337346 0,02957712 ! tumor necrosis factor receptor superfamily binding GO:0032813 29 29 0,000 0,02337346 0,02956664 ! acetylglucosaminyltransferase activity GO:0008375 30 29 0,000 0,02337346 0,02955617 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,02337346 0,02954571 ! gene silencing GO:0016458 29 29 0,000 0,02337346 0,02953526 ! hormone binding GO:0042562 30 30 0,000 0,02417044 0,03053153 ! negative regulation of DNA metabolic process GO:0051053 34 30 0,000 0,02417044 0,03052073 ! inner ear morphogenesis GO:0042472 31 30 0,000 0,02417044 0,03050994 ! GPI anchor biosynthetic process GO:0006506 32 30 0,000 0,02417044 0,03049916 ! acrosomal vesicle GO:0001669 32 30 0,000 0,02417044 0,03048839 ! negative regulation of DNA binding GO:0043392 31 30 0,000 0,02417044 0,03047762 ! triglyceride metabolic process GO:0006641 31 30 0,000 0,02417044 0,03046687 ! glutamate receptor activity GO:0008066 33 30 0,000 0,02417044 0,03045612 ! ceramide metabolic process GO:0006672 30 30 0,000 0,02417044 0,03044537 ! cell fate specification GO:0001708 31 30 0,000 0,02417044 0,03043464 ! hexose biosynthetic process GO:0019319 32 30 0,000 0,02417044 0,03042391 ! PDZ domain binding GO:0030165 32 30 0,000 0,02417044 0,03041319 ! AP-type membrane coat adaptor complex GO:0030119 31 30 0,000 0,02417044 0,03040248 GO:0030131|clathrin adaptor complex, ! embryonic epithelial tube formation GO:0001838 32 30 0,000 0,02417044 0,03039177 ! negative regulation of protein transport GO:0051224 30 30 0,000 0,02417044 0,03038107 ! negative regulation of protein complex assembly GO:0031333 30 30 0,000 0,02417044 0,03037038 ! regulation of JAK-STAT cascade GO:0046425 32 30 0,000 0,02417044 0,0303597 ! drug binding GO:0008144 30 30 0,000 0,02417044 0,03034903 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 33 30 0,000 0,02417044 0,03033836 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,02417044 0,0303277 ! regulation of systemic arterial blood pressure GO:0003073 32 30 0,000 0,02417044 0,03031705 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 31 30 0,000 0,02417044 0,0303064 ! aminopeptidase activity GO:0004177 32 30 0,000 0,02417044 0,03029576 ! detection of light stimulus GO:0009583 30 30 0,000 0,02417044 0,03028513 ! L-amino acid transmembrane transporter activity GO:0015179 30 30 0,000 0,02417044 0,03027451 ! regulation of microtubule-based process GO:0032886 32 30 0,000 0,02417044 0,0302639 ! cysteine-type endopeptidase inhibitor activity GO:0004869 32 30 0,000 0,02417044 0,03025329 ! meiosis I GO:0007127 31 31 0,000 0,02496682 0,03123914 ! negative regulation of cell adhesion GO:0007162 33 31 0,000 0,02496682 0,0312282 ! striated muscle cell differentiation GO:0051146 31 31 0,000 0,02496682 0,03121726 ! GPI anchor metabolic process GO:0006505 33 31 0,000 0,02496682 0,03120633 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,02496682 0,03119542 ! spliceosome assembly GO:0000245 32 31 0,000 0,02496682 0,0311845 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 32 31 0,000 0,02496682 0,0311736 GO:0004601|peroxidase activity, ! unsaturated fatty acid biosynthetic process GO:0006636 32 31 0,000 0,02496682 0,0311627 ! NAD or NADH binding GO:0051287 31 31 0,000 0,02496682 0,03115182 ! positive regulation of neurogenesis GO:0050769 32 31 0,000 0,02496682 0,03114094 ! cyclic nucleotide metabolic process GO:0009187 31 31 0,000 0,02496682 0,03113006 ! nucleotide catabolic process GO:0009166 32 31 0,000 0,02496682 0,0311192 ! condensed nuclear chromosome GO:0000794 32 31 0,000 0,02496682 0,03110834 ! regulation of pH GO:0006885 31 31 0,000 0,02496682 0,03109749 ! protein methyltransferase activity GO:0008276 36 31 0,000 0,02496682 0,03108665 ! acute-phase response GO:0006953 32 31 0,000 0,02496682 0,03107581 ! peptide transport GO:0015833 32 31 0,000 0,02496682 0,03106498 ! respiratory gaseous exchange GO:0007585 32 31 0,000 0,02496682 0,03105416 ! DNA integrity checkpoint GO:0031570 34 31 0,000 0,02496682 0,03104335 ! Golgi-associated vesicle membrane GO:0030660 34 31 0,000 0,02496682 0,03103254 ! regulation of protein stability GO:0031647 32 31 0,000 0,02496682 0,03102175 ! sarcolemma GO:0042383 33 31 0,000 0,02496682 0,03101096 ! vesicle localization GO:0051648 32 31 0,000 0,02496682 0,03100017 ! microtubule organizing center part GO:0044450 34 31 0,000 0,02496682 0,0309894 ! DNA helicase activity GO:0003678 34 32 0,000 0,0257626 0,03196603 ! NADP or NADPH binding GO:0050661 33 32 0,000 0,0257626 0,03195493 ! pigment biosynthetic process GO:0046148 34 32 0,000 0,0257626 0,03194383 ! purinergic nucleotide receptor activity GO:0001614 34 32 0,000 0,0257626 0,03193275 GO:0016502|nucleotide receptor activity, ! female gonad development GO:0008585 32 32 0,000 0,0257626 0,03192167 ! late endosome membrane GO:0031902 32 32 0,000 0,0257626 0,03191059 ! positive regulation of cell development GO:0010720 33 32 0,000 0,0257626 0,03189953 ! regulation of Wnt receptor signaling pathway GO:0030111 35 32 0,000 0,0257626 0,03188847 ! hindbrain development GO:0030902 35 32 0,000 0,0257626 0,03187742 ! aerobic respiration GO:0009060 32 32 0,000 0,0257626 0,03186638 ! positive regulation of catabolic process GO:0009896 34 32 0,000 0,0257626 0,03185535 ! regulation of B cell activation GO:0050864 36 32 0,000 0,0257626 0,03184432 ! regulation of muscle development GO:0048634 33 32 0,000 0,0257626 0,0318333 GO:0016202|regulation of striated muscle tissue development, ! cation:sugar symporter activity GO:0005402 32 32 0,000 0,0257626 0,03182229 GO:0005351|sugar:hydrogen symporter activity, ! sphingoid metabolic process GO:0046519 32 32 0,000 0,0257626 0,03181129 ! response to ionizing radiation GO:0010212 33 32 0,000 0,0257626 0,03180029 ! flagellum GO:0019861 32 32 0,000 0,0257626 0,0317893 ! regulation of lymphocyte mediated immunity GO:0002706 36 32 0,000 0,0257626 0,03177832 ! I band GO:0031674 35 32 0,000 0,0257626 0,03176735 ! JAK-STAT cascade GO:0007259 34 32 0,000 0,0257626 0,03175638 ! double-stranded RNA binding GO:0003725 33 32 0,000 0,0257626 0,03174542 ! cellular response to insulin stimulus GO:0032869 37 32 0,000 0,0257626 0,03173447 ! adult locomotory behavior GO:0008344 33 32 0,000 0,0257626 0,03172353 ! pyrimidine nucleotide metabolic process GO:0006220 37 32 0,000 0,0257626 0,0317126 ! positive regulation of transcription factor activity GO:0051091 34 33 0,000 0,02655779 0,03268017 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 34 33 0,000 0,02655779 0,03266891 ! establishment or maintenance of cell polarity GO:0007163 33 33 0,000 0,02655779 0,03265766 ! platelet alpha granule lumen GO:0031093 34 33 0,000 0,02655779 0,03264642 ! negative regulation of binding GO:0051100 34 33 0,000 0,02655779 0,03263519 ! organelle envelope lumen GO:0031970 34 33 0,000 0,02655779 0,03262396 ! protein targeting to membrane GO:0006612 35 33 0,000 0,02655779 0,03261274 ! vesicle coat GO:0030120 36 33 0,000 0,02655779 0,03260153 ! monosaccharide biosynthetic process GO:0046364 35 33 0,000 0,02655779 0,03259033 ! glial cell differentiation GO:0010001 33 33 0,000 0,02655779 0,03257913 ! cell junction organization GO:0034330 35 33 0,000 0,02655779 0,03256794 ! tissue remodeling GO:0048771 35 33 0,000 0,02655779 0,03255676 ! segmentation GO:0035282 34 33 0,000 0,02655779 0,03254559 ! steroid hormone receptor binding GO:0035258 33 33 0,000 0,02655779 0,03253443 ! positive regulation of gene-specific transcription GO:0043193 34 33 0,000 0,02655779 0,03252327 ! energy coupled proton transport, down electrochemical gradient GO:0015985 33 33 0,000 0,02655779 0,03251212 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 35 33 0,000 0,02655779 0,03250098 ! hormone biosynthetic process GO:0042446 33 33 0,000 0,02655779 0,03248984 ! androgen receptor signaling pathway GO:0030521 34 33 0,000 0,02655779 0,03247872 ! O-acyltransferase activity GO:0008374 33 33 0,000 0,02655779 0,0324676 ! response to xenobiotic stimulus GO:0009410 33 33 0,000 0,02655779 0,03245649 ! cellular amide metabolic process GO:0043603 34 34 0,000 0,02735238 0,03341613 ! sugar transmembrane transporter activity GO:0051119 34 34 0,000 0,02735238 0,0334047 GO:0015144|carbohydrate transmembrane transporter activity, ! neural tube development GO:0021915 36 34 0,000 0,02735238 0,03339328 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 34 0,000 0,02735238 0,03338187 ! neutral lipid metabolic process GO:0006638 35 34 0,000 0,02735238 0,03337046 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 34 34 0,000 0,02735238 0,03335907 ! telencephalon development GO:0021537 34 34 0,000 0,02735238 0,03334768 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 35 34 0,000 0,02735238 0,0333363 ! integral to Golgi membrane GO:0030173 34 34 0,000 0,02735238 0,03332492 ! intramolecular oxidoreductase activity GO:0016860 35 34 0,000 0,02735238 0,03331356 ! development of primary female sexual characteristics GO:0046545 34 34 0,000 0,02735238 0,0333022 GO:0046660|female sex differentiation, ! DNA-directed RNA polymerase activity GO:0003899 35 34 0,000 0,02735238 0,03329085 GO:0034062|RNA polymerase activity, ! leukocyte chemotaxis GO:0030595 35 34 0,000 0,02735238 0,0332795 GO:0060326|cell chemotaxis, ! sodium channel activity GO:0005272 36 34 0,000 0,02735238 0,03326817 ! carboxypeptidase activity GO:0004180 35 34 0,000 0,02735238 0,03325684 ! spermatid development GO:0007286 34 34 0,000 0,02735238 0,03324552 ! BMP signaling pathway GO:0030509 35 34 0,000 0,02735238 0,03323421 ! specific RNA polymerase II transcription factor activity GO:0003704 35 34 0,000 0,02735238 0,03322291 ! mitotic cell cycle checkpoint GO:0007093 35 35 0,000 0,02814638 0,03417569 ! regulation of intracellular protein transport GO:0033157 37 35 0,000 0,02814638 0,03416408 ! metanephros development GO:0001656 35 35 0,000 0,02814638 0,03415247 ! regulation of action potential in neuron GO:0019228 38 35 0,000 0,02814638 0,03414087 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 39 35 0,000 0,02814638 0,03412927 ! cytokine production GO:0001816 35 35 0,000 0,02814638 0,03411769 ! carbon-carbon lyase activity GO:0016830 35 35 0,000 0,02814638 0,03410611 ! embryonic pattern specification GO:0009880 36 35 0,000 0,02814638 0,03409454 ! regulation of metal ion transport GO:0010959 38 35 0,000 0,02814638 0,03408298 ! energy reserve metabolic process GO:0006112 36 35 0,000 0,02814638 0,03407143 ! metalloexopeptidase activity GO:0008235 36 35 0,000 0,02814638 0,03405988 ! protein serine/threonine phosphatase complex GO:0008287 38 35 0,000 0,02814638 0,03404834 ! phagocytosis GO:0006909 37 35 0,000 0,02814638 0,03403681 ! regulation of ARF protein signal transduction GO:0032012 40 35 0,000 0,02814638 0,03402529 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 37 35 0,000 0,02814638 0,03401378 ! ion transmembrane transport GO:0034220 35 35 0,000 0,02814638 0,03400227 ! neuropeptide receptor activity GO:0008188 35 35 0,000 0,02814638 0,03399077 ! oxygen binding GO:0019825 36 35 0,000 0,02814638 0,03397928 ! regulation of leukocyte mediated immunity GO:0002703 39 35 0,000 0,02814638 0,0339678 ! peripheral nervous system development GO:0007422 37 35 0,000 0,02814638 0,03395632 ! female gamete generation GO:0007292 38 35 0,000 0,02814638 0,03394485 ! polyol metabolic process GO:0019751 36 35 0,000 0,02814638 0,03393339 ! negative regulation of adenylate cyclase activity GO:0007194 38 36 0,000 0,02893978 0,03487815 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of hormone secretion GO:0046883 38 36 0,000 0,02893978 0,03486638 ! monocarboxylic acid binding GO:0033293 37 36 0,000 0,02893978 0,03485462 ! polysaccharide biosynthetic process GO:0000271 36 36 0,000 0,02893978 0,03484287 ! regulation of axonogenesis GO:0050770 39 36 0,000 0,02893978 0,03483113 ! glycerol ether metabolic process GO:0006662 37 36 0,000 0,02893978 0,03481939 ! regulation of proteolysis GO:0030162 37 36 0,000 0,02893978 0,03480767 ! integral to endoplasmic reticulum membrane GO:0030176 36 36 0,000 0,02893978 0,03479595 ! regulation of adaptive immune response GO:0002819 40 36 0,000 0,02893978 0,03478423 ! oxidoreduction coenzyme metabolic process GO:0006733 37 36 0,000 0,02893978 0,03477253 ! isoprenoid metabolic process GO:0006720 37 36 0,000 0,02893978 0,03476083 ! spermatid differentiation GO:0048515 36 36 0,000 0,02893978 0,03474915 ! phosphoinositide biosynthetic process GO:0046489 38 36 0,000 0,02893978 0,03473746 ! ER to Golgi vesicle-mediated transport GO:0006888 36 36 0,000 0,02893978 0,03472579 ! condensed chromosome kinetochore GO:0000777 37 36 0,000 0,02893978 0,03471413 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 38 36 0,000 0,02893978 0,03470247 ! neuropeptide binding GO:0042923 36 36 0,000 0,02893978 0,03469082 ! organic anion transport GO:0015711 37 36 0,000 0,02893978 0,03467918 ! carbohydrate homeostasis GO:0033500 38 36 0,000 0,02893978 0,03466755 GO:0042593|glucose homeostasis, ! complement activation GO:0006956 39 36 0,000 0,02893978 0,03465592 ! antigen binding GO:0003823 36 36 0,000 0,02893978 0,0346443 ! extrinsic to plasma membrane GO:0019897 36 36 0,000 0,02893978 0,03463269 ! cytokinesis GO:0000910 40 36 0,000 0,02893978 0,03462109 ! coated pit GO:0005905 42 36 0,000 0,02893978 0,0346095 ! positive regulation of leukocyte proliferation GO:0070665 40 36 0,000 0,02893978 0,03459791 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein amino acid N-linked glycosylation GO:0006487 40 37 0,000 0,02973259 0,03553383 ! ribonucleoside metabolic process GO:0009119 43 37 0,000 0,02973259 0,03552194 ! DNA-dependent ATPase activity GO:0008094 39 37 0,000 0,02973259 0,03551006 ! regulation of T cell differentiation GO:0045580 41 37 0,000 0,02973259 0,03549819 ! biopolymer methylation GO:0043414 42 37 0,000 0,02973259 0,03548632 ! intrinsic to Golgi membrane GO:0031228 37 37 0,000 0,02973259 0,03547447 ! protein homooligomerization GO:0051260 38 37 0,000 0,02973259 0,03546262 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 38 37 0,000 0,02973259 0,03545078 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 41 37 0,000 0,02973259 0,03543895 ! regulation of T cell proliferation GO:0042129 41 37 0,000 0,02973259 0,03542712 ! amino acid binding GO:0016597 40 37 0,000 0,02973259 0,0354153 ! maintenance of protein location GO:0045185 38 37 0,000 0,02973259 0,0354035 ! maintenance of location in cell GO:0051651 38 37 0,000 0,02973259 0,03539169 ! solute:hydrogen symporter activity GO:0015295 37 37 0,000 0,02973259 0,0353799 ! proton-transporting two-sector ATPase complex GO:0016469 37 37 0,000 0,02973259 0,03536812 ! ear morphogenesis GO:0042471 39 38 0,000 0,03052481 0,0362984 ! organic ether metabolic process GO:0018904 39 38 0,000 0,03052481 0,03628631 ! alcohol biosynthetic process GO:0046165 40 38 0,000 0,03052481 0,03627424 ! monovalent inorganic cation homeostasis GO:0055067 39 38 0,000 0,03052481 0,03626217 ! positive regulation of DNA binding GO:0043388 39 38 0,000 0,03052481 0,03625011 ! B cell differentiation GO:0030183 40 38 0,000 0,03052481 0,03623806 ! clathrin coat GO:0030118 43 38 0,000 0,03052481 0,03622602 ! regulation of endocytosis GO:0030100 39 38 0,000 0,03052481 0,03621398 ! dorsal/ventral pattern formation GO:0009953 38 38 0,000 0,03052481 0,03620196 ! positive regulation of defense response GO:0031349 38 38 0,000 0,03052481 0,03618994 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 38 0,000 0,03052481 0,03617793 ! condensed chromosome, centromeric region GO:0000779 39 38 0,000 0,03052481 0,03616592 ! learning GO:0007612 42 38 0,000 0,03052481 0,03615393 ! negative regulation of protein complex disassembly GO:0043242 40 38 0,000 0,03052481 0,03614194 ! monocarboxylic acid transport GO:0015718 39 38 0,000 0,03052481 0,03612996 ! endosome transport GO:0016197 40 38 0,000 0,03052481 0,03611799 ! hormone-mediated signaling GO:0009755 39 38 0,000 0,03052481 0,03610602 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 40 38 0,000 0,03052481 0,03609407 ! N-methyltransferase activity GO:0008170 42 38 0,000 0,03052481 0,03608212 ! cytosolic large ribosomal subunit GO:0022625 38 38 0,000 0,03052481 0,03607018 ! pigment metabolic process GO:0042440 42 38 0,000 0,03052481 0,03605825 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 38 38 0,000 0,03052481 0,03604633 ! RNA modification GO:0009451 39 38 0,000 0,03052481 0,03603441 ! regulation of nucleocytoplasmic transport GO:0046822 41 39 0,000 0,03131643 0,0369567 ! Notch signaling pathway GO:0007219 41 39 0,000 0,03131643 0,03694449 ! induction of apoptosis by extracellular signals GO:0008624 39 39 0,000 0,03131643 0,03693229 ! keratin filament GO:0045095 41 39 0,000 0,03131643 0,0369201 ! ER-Golgi intermediate compartment GO:0005793 42 39 0,000 0,03131643 0,03690791 ! peroxisomal membrane GO:0005778 40 39 0,000 0,03131643 0,03689574 GO:0031903|microbody membrane, ! mitochondrial respiratory chain complex I GO:0005747 39 39 0,000 0,03131643 0,03688357 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! actin filament binding GO:0051015 39 39 0,000 0,03131643 0,03687141 ! regulation of protein secretion GO:0050708 41 39 0,000 0,03131643 0,03685925 ! cis-trans isomerase activity GO:0016859 39 39 0,000 0,03131643 0,03684711 ! regulation of cell morphogenesis involved in differentiation GO:0010769 42 39 0,000 0,03131643 0,03683497 ! viral infectious cycle GO:0019058 39 39 0,000 0,03131643 0,03682284 ! mammary gland development GO:0030879 41 39 0,000 0,03131643 0,03681072 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 39 0,000 0,03131643 0,03679861 ! amine receptor activity GO:0008227 41 39 0,000 0,03131643 0,03678651 ! monosaccharide binding GO:0048029 39 39 0,000 0,03131643 0,03677441 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 39 39 0,000 0,03131643 0,03676232 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! phosphotransferase activity, phosphate group as acceptor GO:0016776 44 40 0,000 0,03210746 0,03767852 ! response to estrogen stimulus GO:0043627 41 40 0,000 0,03210746 0,03766615 ! peptide metabolic process GO:0006518 41 40 0,000 0,03210746 0,03765378 ! regulation of Rab protein signal transduction GO:0032483 41 40 0,000 0,03210746 0,03764141 GO:0032313|regulation of Rab GTPase activity, ! T cell differentiation GO:0030217 45 40 0,000 0,03210746 0,03762906 ! regulation of multicellular organism growth GO:0040014 42 40 0,000 0,03210746 0,03761672 ! regulation of gene expression, epigenetic GO:0040029 43 40 0,000 0,03210746 0,03760438 ! neuron migration GO:0001764 42 40 0,000 0,03210746 0,03759205 ! inositol or phosphatidylinositol kinase activity GO:0004428 42 40 0,000 0,03210746 0,03757973 ! structural constituent of muscle GO:0008307 43 40 0,000 0,03210746 0,03756741 ! gliogenesis GO:0042063 40 40 0,000 0,03210746 0,03755511 ! feeding behavior GO:0007631 40 40 0,000 0,03210746 0,03754281 ! protein serine/threonine phosphatase activity GO:0004722 42 40 0,000 0,03210746 0,03753052 ! nucleus organization GO:0006997 40 40 0,000 0,03210746 0,03751824 ! positive regulation of cytokine biosynthetic process GO:0042108 41 40 0,000 0,03210746 0,03750597 ! sulfur compound biosynthetic process GO:0044272 41 40 0,000 0,03210746 0,0374937 ! inorganic anion transmembrane transporter activity GO:0015103 42 40 0,000 0,03210746 0,03748145 ! chromatin remodeling GO:0006338 43 40 0,000 0,03210746 0,0374692 ! activation of adenylate cyclase activity GO:0007190 42 41 0,000 0,0328979 0,03837909 ! positive regulation of binding GO:0051099 42 41 0,000 0,0328979 0,03836656 ! solute:sodium symporter activity GO:0015370 41 41 0,000 0,0328979 0,03835403 ! regulation of translational initiation GO:0006446 41 41 0,000 0,0328979 0,03834152 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 44 41 0,000 0,0328979 0,03832901 GO:0046328|regulation of JNK cascade, ! mesenchymal cell development GO:0014031 43 41 0,000 0,0328979 0,03831651 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! heterocycle biosynthetic process GO:0018130 43 41 0,000 0,0328979 0,03830401 ! regulation of myeloid cell differentiation GO:0045637 43 41 0,000 0,0328979 0,03829153 ! positive regulation of cytokine production GO:0001819 42 41 0,000 0,0328979 0,03827905 ! hydro-lyase activity GO:0016836 44 41 0,000 0,0328979 0,03826658 ! positive regulation of protein transport GO:0051222 44 41 0,000 0,0328979 0,03825412 ! receptor-mediated endocytosis GO:0006898 43 41 0,000 0,0328979 0,03824167 ! regulation of neuron projection development GO:0010975 44 41 0,000 0,0328979 0,03822922 ! metal cluster binding GO:0051540 43 41 0,000 0,0328979 0,03821679 GO:0051536|iron-sulfur cluster binding, ! embryonic skeletal system morphogenesis GO:0048704 42 41 0,000 0,0328979 0,03820436 ! development of primary male sexual characteristics GO:0046546 41 41 0,000 0,0328979 0,03819194 ! Rab GTPase activator activity GO:0005097 42 41 0,000 0,0328979 0,03817953 ! RNA catabolic process GO:0006401 44 42 0,000 0,03368775 0,03908348 ! organellar ribosome GO:0000313 43 42 0,000 0,03368775 0,03907079 GO:0005761|mitochondrial ribosome, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 44 42 0,000 0,03368775 0,0390581 ! MHC protein complex GO:0042611 42 42 0,000 0,03368775 0,03904542 ! regulation of epithelial cell proliferation GO:0050678 44 42 0,000 0,03368775 0,03903276 ! icosanoid metabolic process GO:0006690 43 42 0,000 0,03368775 0,03902009 ! chemokine activity GO:0008009 42 42 0,000 0,03368775 0,03900744 ! ruffle GO:0001726 44 42 0,000 0,03368775 0,0389948 ! pigmentation GO:0043473 46 42 0,000 0,03368775 0,03898216 ! developmental growth GO:0048589 42 42 0,000 0,03368775 0,03896953 ! methylation GO:0032259 47 42 0,000 0,03368775 0,03895691 ! glycolysis GO:0006096 42 42 0,000 0,03368775 0,0389443 ! morphogenesis of embryonic epithelium GO:0016331 44 42 0,000 0,03368775 0,0389317 ! regulation of tube size GO:0035150 44 42 0,000 0,03368775 0,0389191 GO:0050880|regulation of blood vessel size, ! branching morphogenesis of a tube GO:0048754 43 42 0,000 0,03368775 0,03890652 ! general RNA polymerase II transcription factor activity GO:0016251 44 42 0,000 0,03368775 0,03889394 ! cellular amino acid derivative biosynthetic process GO:0042398 43 42 0,000 0,03368775 0,03888137 ! positive regulation of adenylate cyclase activity GO:0045762 44 43 0,000 0,034477 0,03977945 ! transferase activity, transferring pentosyl groups GO:0016763 45 43 0,000 0,034477 0,0397666 ! epithelial cell differentiation GO:0030855 45 43 0,000 0,034477 0,03975376 ! detection of stimulus involved in sensory perception GO:0050906 43 43 0,000 0,034477 0,03974092 ! sulfotransferase activity GO:0008146 44 43 0,000 0,034477 0,0397281 ! cellular polysaccharide metabolic process GO:0044264 44 43 0,000 0,034477 0,03971529 ! channel regulator activity GO:0016247 46 43 0,000 0,034477 0,03970248 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 45 43 0,000 0,034477 0,03968968 ! synaptosome GO:0019717 47 43 0,000 0,034477 0,03967689 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 45 44 0,000 0,03526567 0,04057143 ! platelet alpha granule GO:0031091 46 44 0,000 0,03526567 0,04055836 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 44 44 0,000 0,03526567 0,0405453 ! regulation of ossification GO:0030278 48 44 0,000 0,03526567 0,04053225 ! cell recognition GO:0008037 46 44 0,000 0,03526567 0,04051921 ! positive regulation of cyclase activity GO:0031281 45 44 0,000 0,03526567 0,04050618 ! regulation of lymphocyte differentiation GO:0045619 48 44 0,000 0,03526567 0,04049315 ! regulation of actin filament polymerization GO:0030833 45 44 0,000 0,03526567 0,04048014 ! cellular component disassembly GO:0022411 45 44 0,000 0,03526567 0,04046713 ! regulation of protein complex disassembly GO:0043244 46 44 0,000 0,03526567 0,04045413 ! regulation of ion transport GO:0043269 47 44 0,000 0,03526567 0,04044114 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 50 44 0,000 0,03526567 0,04042816 ! inner ear development GO:0048839 46 44 0,000 0,03526567 0,04041518 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 48 44 0,000 0,03526567 0,04040222 ! amino acid transmembrane transporter activity GO:0015171 44 44 0,000 0,03526567 0,04038926 ! negative regulation of immune system process GO:0002683 49 44 0,000 0,03526567 0,04037631 ! chemokine receptor binding GO:0042379 44 44 0,000 0,03526567 0,04036337 ! regulation of mast cell proliferation GO:0070666 48 44 0,000 0,03526567 0,04035043 ! regulation of action potential GO:0001508 50 45 0,000 0,03605374 0,04123892 ! regulation of gene-specific transcription GO:0032583 47 45 0,000 0,03605374 0,04122572 ! cellular amino acid biosynthetic process GO:0008652 47 45 0,000 0,03605374 0,04121252 ! response to temperature stimulus GO:0009266 45 45 0,000 0,03605374 0,04119933 ! nucleoside monophosphate biosynthetic process GO:0009124 50 45 0,000 0,03605374 0,04118615 ! positive regulation of lyase activity GO:0051349 46 45 0,000 0,03605374 0,04117298 ! regulation of neuron apoptosis GO:0043523 45 45 0,000 0,03605374 0,04115982 ! excretion GO:0007588 46 45 0,000 0,03605374 0,04114667 ! protein phosphatase regulator activity GO:0019888 49 45 0,000 0,03605374 0,04113352 ! JNK cascade GO:0007254 45 45 0,000 0,03605374 0,04112038 ! SH3/SH2 adaptor activity GO:0005070 48 45 0,000 0,03605374 0,04110725 ! regulation of cell shape GO:0008360 46 45 0,000 0,03605374 0,04109413 ! epithelial tube morphogenesis GO:0060562 47 45 0,000 0,03605374 0,04108102 ! microbody part GO:0044438 46 45 0,000 0,03605374 0,04106792 GO:0044439|peroxisomal part, ! auxiliary transport protein activity GO:0015457 50 46 0,000 0,03684123 0,04195154 ! ATP synthesis coupled electron transport GO:0042773 46 46 0,000 0,03684123 0,04193817 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! microtubule binding GO:0008017 49 46 0,000 0,03684123 0,0419248 ! regulation of inflammatory response GO:0050727 46 46 0,000 0,03684123 0,04191144 ! transport vesicle GO:0030133 49 46 0,000 0,03684123 0,0418981 ! glutamine family amino acid metabolic process GO:0009064 49 46 0,000 0,03684123 0,04188476 ! synapse organization GO:0050808 51 46 0,000 0,03684123 0,04187143 ! nuclear matrix GO:0016363 49 46 0,000 0,03684123 0,04185811 ! striated muscle contraction GO:0006941 49 46 0,000 0,03684123 0,04184479 ! unsaturated fatty acid metabolic process GO:0033559 47 46 0,000 0,03684123 0,04183149 ! antioxidant activity GO:0016209 47 46 0,000 0,03684123 0,04181819 ! activation of caspase activity GO:0006919 49 46 0,000 0,03684123 0,0418049 ! aging GO:0007568 48 46 0,000 0,03684123 0,04179162 ! male sex differentiation GO:0046661 46 46 0,000 0,03684123 0,04177835 ! coated vesicle membrane GO:0030662 49 46 0,000 0,03684123 0,04176509 ! RNA elongation from RNA polymerase II promoter GO:0006368 48 46 0,000 0,03684123 0,04175183 ! regulation of leukocyte proliferation GO:0070663 50 46 0,000 0,03684123 0,04173859 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! protein amino acid lipidation GO:0006497 50 47 0,000 0,03762812 0,04261656 ! stress-activated protein kinase signaling pathway GO:0031098 47 47 0,000 0,03762812 0,04260305 ! carbohydrate transport GO:0008643 47 47 0,000 0,03762812 0,04258955 ! proteasome complex GO:0000502 48 47 0,000 0,03762812 0,04257605 ! immunoglobulin mediated immune response GO:0016064 50 47 0,000 0,03762812 0,04256257 ! phosphatase regulator activity GO:0019208 51 47 0,000 0,03762812 0,04254909 ! vesicle organization GO:0016050 50 47 0,000 0,03762812 0,04253562 ! vascular process in circulatory system GO:0003018 49 47 0,000 0,03762812 0,04252216 ! cell cortex part GO:0044448 51 47 0,000 0,03762812 0,04250871 ! lipid modification GO:0030258 49 48 0,000 0,03841443 0,04338328 ! cytokine-mediated signaling pathway GO:0019221 49 48 0,000 0,03841443 0,04336956 ! morphogenesis of a branching structure GO:0001763 49 48 0,000 0,03841443 0,04335585 ! mitochondrial transport GO:0006839 49 48 0,000 0,03841443 0,04334216 ! viral reproductive process GO:0022415 52 48 0,000 0,03841443 0,04332847 ! leukocyte migration GO:0050900 49 48 0,000 0,03841443 0,04331478 ! neuromuscular process GO:0050905 49 48 0,000 0,03841443 0,04330111 ! gastrulation GO:0007369 50 48 0,000 0,03841443 0,04328745 ! detection of abiotic stimulus GO:0009582 48 48 0,000 0,03841443 0,04327379 ! heterocycle catabolic process GO:0046700 53 48 0,000 0,03841443 0,04326015 ! B cell mediated immunity GO:0019724 51 48 0,000 0,03841443 0,04324651 ! single-stranded DNA binding GO:0003697 49 49 0,000 0,03920014 0,04411715 ! intrinsic to endoplasmic reticulum membrane GO:0031227 50 49 0,000 0,03920014 0,04410325 ! positive regulation of organelle organization GO:0010638 49 49 0,000 0,03920014 0,04408936 ! water-soluble vitamin metabolic process GO:0006767 50 49 0,000 0,03920014 0,04407548 ! nucleosome GO:0000786 49 49 0,000 0,03920014 0,0440616 ! kinetochore GO:0000776 50 49 0,000 0,03920014 0,04404774 ! membrane fusion GO:0006944 51 49 0,000 0,03920014 0,04403388 ! endocrine system development GO:0035270 49 49 0,000 0,03920014 0,04402004 ! RNA elongation GO:0006354 51 49 0,000 0,03920014 0,0440062 ! glycosaminoglycan metabolic process GO:0030203 53 50 0,000 0,03998527 0,04487348 ! regulation of actin polymerization or depolymerization GO:0008064 51 50 0,000 0,03998527 0,04485938 ! basement membrane GO:0005604 51 50 0,000 0,03998527 0,04484529 ! regulation of intracellular transport GO:0032386 52 50 0,000 0,03998527 0,04483121 ! maintenance of location GO:0051235 51 50 0,000 0,03998527 0,04481714 ! cell redox homeostasis GO:0045454 51 50 0,000 0,03998527 0,04480308 ! integrin binding GO:0005178 53 50 0,000 0,03998527 0,04478902 ! amino acid activation GO:0043038 50 50 0,000 0,03998527 0,04477498 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of organelle localization GO:0051656 53 50 0,000 0,03998527 0,04476094 ! regulation of bone remodeling GO:0046850 55 51 0,000 0,04076981 0,04562488 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 52 51 0,000 0,04076981 0,04561059 ! late endosome GO:0005770 51 51 0,000 0,04076981 0,0455963 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 56 51 0,000 0,04076981 0,04558203 ! ligase activity, forming carbon-oxygen bonds GO:0016875 51 51 0,000 0,04076981 0,04556776 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! negative regulation of response to stimulus GO:0048585 55 51 0,000 0,04076981 0,0455535 ! carbon-oxygen lyase activity GO:0016835 54 51 0,000 0,04076981 0,04553925 ! skeletal muscle fiber development GO:0048741 54 51 0,000 0,04076981 0,04552501 ! lipoprotein biosynthetic process GO:0042158 54 51 0,000 0,04076981 0,04551078 ! heart morphogenesis GO:0003007 54 51 0,000 0,04076981 0,04549656 ! steroid hormone receptor activity GO:0003707 53 51 0,000 0,04076981 0,04548235 ! antiporter activity GO:0015297 52 51 0,000 0,04076981 0,04546814 ! respiratory electron transport chain GO:0022904 52 52 0,000 0,04155376 0,04632797 ! Golgi-associated vesicle GO:0005798 55 52 0,000 0,04155376 0,04631351 ! sphingolipid metabolic process GO:0006665 53 52 0,000 0,04155376 0,04629906 ! cell maturation GO:0048469 55 52 0,000 0,04155376 0,04628462 ! regulation of protein polymerization GO:0032271 53 52 0,000 0,04155376 0,04627019 ! regulation of actin filament length GO:0030832 53 52 0,000 0,04155376 0,04625576 ! regulation of cell projection organization GO:0031344 55 52 0,000 0,04155376 0,04624135 ! chloride transport GO:0006821 53 52 0,000 0,04155376 0,04622694 ! positive regulation of caspase activity GO:0043280 55 52 0,000 0,04155376 0,04621255 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 55 52 0,000 0,04155376 0,04619816 ! regulation of muscle contraction GO:0006937 56 52 0,000 0,04155376 0,04618378 ! negative regulation of cytoskeleton organization GO:0051494 57 52 0,000 0,04155376 0,04616941 ! glucose catabolic process GO:0006007 52 52 0,000 0,04155376 0,04615505 ! generation of a signal involved in cell-cell signaling GO:0003001 54 52 0,000 0,04155376 0,0461407 ! small ribosomal subunit GO:0015935 52 52 0,000 0,04155376 0,04612636 ! cytokine receptor activity GO:0004896 53 52 0,000 0,04155376 0,04611202 ! activation of phospholipase C activity GO:0007202 55 53 0,000 0,04233713 0,04696672 GO:0010863|positive regulation of phospholipase C activity, ! nucleoside monophosphate metabolic process GO:0009123 58 53 0,000 0,04233713 0,04695214 ! nucleoside metabolic process GO:0009116 61 53 0,000 0,04233713 0,04693756 ! synaptic vesicle GO:0008021 57 53 0,000 0,04233713 0,04692299 ! viral reproduction GO:0016032 57 53 0,000 0,04233713 0,04690843 ! proton transport GO:0015992 53 53 0,000 0,04233713 0,04689388 ! mRNA binding GO:0003729 55 53 0,000 0,04233713 0,04687934 ! single fertilization GO:0007338 55 53 0,000 0,04233713 0,04686481 ! axon GO:0030424 58 54 0,000 0,0431199 0,04771651 ! heat shock protein binding GO:0031072 54 54 0,000 0,0431199 0,04770173 ! regulation of neurotransmitter levels GO:0001505 60 54 0,000 0,0431199 0,04768695 ! positive regulation of phospholipase activity GO:0010518 56 54 0,000 0,0431199 0,04767219 ! tRNA processing GO:0008033 55 54 0,000 0,0431199 0,04765744 ! regulation of cellular response to stress GO:0080135 57 54 0,000 0,0431199 0,04764269 ! regulation of protein catabolic process GO:0042176 57 54 0,000 0,0431199 0,04762795 ! DNA catabolic process GO:0006308 55 54 0,000 0,0431199 0,04761323 ! regulation of tissue remodeling GO:0034103 58 54 0,000 0,0431199 0,04759851 ! regulation of cellular component size GO:0032535 56 55 0,000 0,04390209 0,04844697 ! hydrogen transport GO:0006818 55 55 0,000 0,04390209 0,048432 ! glycerophospholipid biosynthetic process GO:0046474 59 55 0,000 0,04390209 0,04841704 ! large ribosomal subunit GO:0015934 56 55 0,000 0,04390209 0,04840209 ! protein amino acid autophosphorylation GO:0046777 57 55 0,000 0,04390209 0,04838715 ! positive regulation of secretion GO:0051047 60 56 0,000 0,0446837 0,04923341 ! regulation of mitosis GO:0007088 56 56 0,000 0,0446837 0,04921823 GO:0051783|regulation of nuclear division, ! actin filament organization GO:0007015 59 56 0,000 0,0446837 0,04920305 ! regulation of phospholipase activity GO:0010517 58 56 0,000 0,0446837 0,04918788 ! coenzyme biosynthetic process GO:0009108 59 56 0,000 0,0446837 0,04917272 ! cellular amino acid catabolic process GO:0009063 59 56 0,000 0,0446837 0,04915758 ! cartilage development GO:0051216 59 56 0,000 0,0446837 0,04914244 ! regulation of protein complex assembly GO:0043254 57 56 0,000 0,0446837 0,04912731 ! receptor signaling protein serine/threonine kinase activity GO:0004702 58 56 0,000 0,0446837 0,04911219 ! mesoderm development GO:0007498 57 56 0,000 0,0446837 0,04909707 ! regulation of transcription factor activity GO:0051090 59 57 0,000 0,04546472 0,04993987 GO:0090046|regulation of transcription regulator activity, ! ear development GO:0043583 60 57 0,000 0,04546472 0,04992451 ! chromosome segregation GO:0007059 59 57 0,000 0,04546472 0,04990916 ! positive regulation of T cell activation GO:0050870 62 57 0,000 0,04546472 0,04989383 ! kidney development GO:0001822 60 57 0,000 0,04546472 0,0498785 ! positive regulation of lipase activity GO:0060193 59 57 0,000 0,04546472 0,04986318 ! integrin-mediated signaling pathway GO:0007229 61 57 0,000 0,04546472 0,04984787 ! adult behavior GO:0030534 60 57 0,000 0,04546472 0,04983257 ! steroid hormone receptor signaling pathway GO:0030518 58 57 0,000 0,04546472 0,04981728 ! myosin complex GO:0016459 59 57 0,000 0,04546472 0,049802 ! regulation of angiogenesis GO:0045765 60 58 0,000 0,04624515 0,05064135 ! lysosomal membrane GO:0005765 59 58 0,000 0,04624515 0,05062582 ! regulation of vesicle-mediated transport GO:0060627 60 58 0,000 0,04624515 0,05061031 ! detection of external stimulus GO:0009581 59 58 0,000 0,04624515 0,0505948 ! secondary metabolic process GO:0019748 59 58 0,000 0,04624515 0,05057931 ! translation initiation factor activity GO:0003743 58 58 0,000 0,04624515 0,05056382 ! dendrite GO:0030425 61 59 0,000 0,047025 0,05140076 ! molecular adaptor activity GO:0060090 65 59 0,000 0,047025 0,05138503 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 60 59 0,000 0,047025 0,05136931 GO:0051213|dioxygenase activity, ! embryonic limb morphogenesis GO:0030326 63 59 0,000 0,047025 0,0513536 GO:0035113|embryonic appendage morphogenesis, ! ubiquitin thiolesterase activity GO:0004221 62 59 0,000 0,047025 0,0513379 ! regulation of heart contraction GO:0008016 62 59 0,000 0,047025 0,05132221 ! copper ion binding GO:0005507 61 59 0,000 0,047025 0,05130653 ! activation of immune response GO:0002253 68 59 0,000 0,047025 0,05129086 ! aminoglycan metabolic process GO:0006022 62 59 0,000 0,047025 0,0512752 ! amine transmembrane transporter activity GO:0005275 59 59 0,000 0,047025 0,05125955 ! cell soma GO:0043025 63 59 0,000 0,047025 0,05124391 ! regulation of homeostatic process GO:0032844 68 59 0,000 0,047025 0,05122827 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 61 60 0,000 0,04780426 0,05206131 ! occluding junction GO:0070160 60 60 0,000 0,04780426 0,05204544 GO:0005923|tight junction, ! oxygen and reactive oxygen species metabolic process GO:0006800 60 60 0,000 0,04780426 0,05202957 ! regulation of cytokine biosynthetic process GO:0042035 63 60 0,000 0,04780426 0,05201372 ! lymphocyte mediated immunity GO:0002449 63 60 0,000 0,04780426 0,05199788 ! chloride channel activity GO:0005254 61 60 0,000 0,04780426 0,05198204 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 62 61 0,000 0,04858294 0,05281269 ! cell cycle checkpoint GO:0000075 64 61 0,000 0,04858294 0,05279662 ! fertilization GO:0009566 64 61 0,000 0,04858294 0,05278056 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 65 61 0,000 0,04858294 0,05276451 ! gonad development GO:0008406 61 61 0,000 0,04858294 0,05274846 ! protein maturation by peptide bond cleavage GO:0051605 64 61 0,000 0,04858294 0,05273243 ! regulation of immune effector process GO:0002697 65 61 0,000 0,04858294 0,05271641 ! amine catabolic process GO:0009310 68 62 0,000 0,04936104 0,05354443 ! phosphoinositide metabolic process GO:0030384 66 62 0,000 0,04936104 0,05352817 ! glycerolipid biosynthetic process GO:0045017 66 62 0,000 0,04936104 0,05351192 ! coated membrane GO:0048475 67 62 0,000 0,04936104 0,05349568 GO:0030117|membrane coat, ! hexose catabolic process GO:0019320 63 62 0,000 0,04936104 0,05347945 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 63 62 0,000 0,04936104 0,05346323 ! extracellular ligand-gated ion channel activity GO:0005230 67 62 0,000 0,04936104 0,05344702 ! germ cell development GO:0007281 62 62 0,000 0,04936104 0,05343082 ! ligand-dependent nuclear receptor activity GO:0004879 65 62 0,000 0,04936104 0,05341463 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 70 63 0,000 0,05013855 0,05423956 ! mitochondrial respiratory chain GO:0005746 65 63 0,000 0,05013855 0,05422313 ! negative regulation of ligase activity GO:0051352 64 63 0,000 0,05013855 0,05420671 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein oligomerization GO:0051259 64 63 0,000 0,05013855 0,05419031 ! transition metal ion transport GO:0000041 65 63 0,000 0,05013855 0,05417391 ! appendage morphogenesis GO:0035107 67 63 0,000 0,05013855 0,05415752 GO:0035108|limb morphogenesis, ! activation of MAPK activity GO:0000187 69 63 0,000 0,05013855 0,05414115 ! cellular defense response GO:0006968 64 63 0,000 0,05013855 0,05412478 ! B cell activation GO:0042113 66 63 0,000 0,05013855 0,05410842 ! antigen processing and presentation GO:0019882 64 63 0,000 0,05013855 0,05409208 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 65 63 0,000 0,05013855 0,05407574 ! microtubule motor activity GO:0003777 67 63 0,000 0,05013855 0,05405941 ! intracellular receptor-mediated signaling pathway GO:0030522 64 63 0,000 0,05013855 0,0540431 ! organelle localization GO:0051640 66 63 0,000 0,05013855 0,05402679 ! respiratory chain GO:0070469 66 64 0,000 0,05091548 0,05484742 ! developmental maturation GO:0021700 67 64 0,000 0,05091548 0,05483088 ! amino acid transport GO:0006865 64 64 0,000 0,05091548 0,05481435 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 66 64 0,000 0,05091548 0,05479783 ! anion channel activity GO:0005253 65 64 0,000 0,05091548 0,05478132 ! cellular hormone metabolic process GO:0034754 65 65 0,000 0,05169183 0,05559986 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 65 0,000 0,05169183 0,05558312 ! negative regulation of cell growth GO:0030308 68 65 0,000 0,05169183 0,05556638 ! nuclear pore GO:0005643 69 65 0,000 0,05169183 0,05554966 ! regulation of MAPKKK cascade GO:0043408 72 65 0,000 0,05169183 0,05553295 ! rhythmic process GO:0048511 66 65 0,000 0,05169183 0,05551625 ! regulation of lipase activity GO:0060191 67 65 0,000 0,05169183 0,05549956 ! adaptive immune response GO:0002250 68 65 0,000 0,05169183 0,05548288 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 69 65 0,000 0,05169183 0,0554662 GO:0060173|limb development, ! skeletal system morphogenesis GO:0048705 66 65 0,000 0,05169183 0,05544954 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 67 65 0,000 0,05169183 0,05543289 ! lipoprotein metabolic process GO:0042157 68 65 0,000 0,05169183 0,05541625 ! DNA-dependent DNA replication GO:0006261 66 65 0,000 0,05169183 0,05539962 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 71 66 0,000 0,0524676 0,05621416 ! endoplasmic reticulum lumen GO:0005788 66 66 0,000 0,0524676 0,0561973 ! urogenital system development GO:0001655 69 66 0,000 0,0524676 0,05618044 ! diacylglycerol binding GO:0019992 71 66 0,000 0,0524676 0,0561636 ! amine binding GO:0043176 70 66 0,000 0,0524676 0,05614677 ! negative regulation of cell size GO:0045792 70 67 0,000 0,05324278 0,05695925 ! mRNA transport GO:0051028 70 67 0,000 0,05324278 0,05694219 ! intracellular protein transmembrane transport GO:0065002 70 67 0,000 0,05324278 0,05692514 ! tubulin binding GO:0015631 70 67 0,000 0,05324278 0,0569081 ! positive regulation of lymphocyte activation GO:0051251 72 67 0,000 0,05324278 0,05689107 ! activation of protein kinase activity GO:0032147 70 67 0,000 0,05324278 0,05687405 ! Ras GTPase binding GO:0017016 70 67 0,000 0,05324278 0,05685705 ! humoral immune response GO:0006959 70 67 0,000 0,05324278 0,05684005 ! nuclear hormone receptor binding GO:0035257 68 67 0,000 0,05324278 0,05682306 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 69 67 0,000 0,05324278 0,05680608 ! ubiquitin ligase complex GO:0000151 71 67 0,000 0,05324278 0,05678912 ! nucleosome assembly GO:0006334 69 67 0,000 0,05324278 0,05677216 ! transcription initiation from RNA polymerase II promoter GO:0006367 71 67 0,000 0,05324278 0,05675521 ! muscle cell differentiation GO:0042692 68 68 0,000 0,05401738 0,05756373 ! fatty acid biosynthetic process GO:0006633 70 68 0,000 0,05401738 0,05754656 ! protein import into nucleus GO:0006606 72 68 0,000 0,05401738 0,0575294 ! lymphocyte differentiation GO:0030098 75 68 0,000 0,05401738 0,05751224 ! protein-DNA complex GO:0032993 69 68 0,000 0,05401738 0,0574951 ! learning or memory GO:0007611 72 68 0,000 0,05401738 0,05747797 ! chloride ion binding GO:0031404 70 68 0,000 0,05401738 0,05746085 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 71 68 0,000 0,05401738 0,05744374 ! chromatin assembly GO:0031497 70 68 0,000 0,05401738 0,05742664 ! leukocyte mediated immunity GO:0002443 71 68 0,000 0,05401738 0,05740954 ! extrinsic to membrane GO:0019898 68 68 0,000 0,05401738 0,05739246 ! calcium channel activity GO:0005262 73 68 0,000 0,05401738 0,05737539 ! ribonucleoprotein complex assembly GO:0022618 69 68 0,000 0,05401738 0,05735833 ! positive regulation of ligase activity GO:0051351 71 69 0,000 0,0547914 0,05816293 ! sarcomere GO:0030017 75 69 0,000 0,0547914 0,05814565 ! cAMP-mediated signaling GO:0019933 72 69 0,000 0,0547914 0,05812837 ! axon guidance GO:0007411 74 69 0,000 0,0547914 0,05811111 ! focal adhesion GO:0005925 75 69 0,000 0,0547914 0,05809385 ! regulation of DNA binding GO:0051101 72 70 0,000 0,05556484 0,05889642 ! carboxylic acid transmembrane transporter activity GO:0046943 71 70 0,000 0,05556484 0,05887895 ! early endosome GO:0005769 79 70 0,000 0,05556484 0,05886148 ! nuclear import GO:0051170 74 70 0,000 0,05556484 0,05884402 ! rRNA processing GO:0006364 70 70 0,000 0,05556484 0,05882658 ! cytosolic ribosome GO:0022626 70 70 0,000 0,05556484 0,05880914 ! cell-matrix adhesion GO:0007160 76 71 0,000 0,0563377 0,05960946 ! FAD binding GO:0050660 72 71 0,000 0,0563377 0,05959181 ! mitochondrial outer membrane GO:0005741 75 71 0,000 0,0563377 0,05957416 ! defense response to bacterium GO:0042742 71 71 0,000 0,0563377 0,05955652 ! steroid biosynthetic process GO:0006694 72 71 0,000 0,0563377 0,0595389 ! monosaccharide catabolic process GO:0046365 72 71 0,000 0,0563377 0,05952128 ! regulation of synaptic transmission GO:0050804 73 71 0,000 0,0563377 0,05950368 ! reproductive structure development GO:0048608 71 71 0,000 0,0563377 0,05948608 ! neurotransmitter transport GO:0006836 73 71 0,000 0,0563377 0,0594685 ! organic acid transmembrane transporter activity GO:0005342 72 71 0,000 0,0563377 0,05945093 ! phospholipase activity GO:0004620 75 71 0,000 0,0563377 0,05943336 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 75 71 0,000 0,0563377 0,05941581 ! cell projection part GO:0044463 75 71 0,000 0,0563377 0,05939827 ! amine biosynthetic process GO:0009309 75 72 0,000 0,05710998 0,06019473 ! meiosis GO:0007126 73 72 0,000 0,05710998 0,06017697 GO:0051327|M phase of meiotic cell cycle, ! elevation of cytosolic calcium ion concentration GO:0007204 77 72 0,000 0,05710998 0,06015922 ! acute inflammatory response GO:0002526 76 72 0,000 0,05710998 0,06014148 ! cholesterol metabolic process GO:0008203 74 72 0,000 0,05710998 0,06012375 ! lipid transporter activity GO:0005319 77 72 0,000 0,05710998 0,06010603 ! regulation of ubiquitin-protein ligase activity GO:0051438 74 72 0,000 0,05710998 0,06008832 ! cell-substrate adherens junction GO:0005924 78 72 0,000 0,05710998 0,06007062 ! negative regulation of transport GO:0051051 74 73 0,000 0,05788168 0,0608644 ! vacuolar membrane GO:0005774 74 73 0,000 0,05788168 0,06084648 ! rRNA metabolic process GO:0016072 73 73 0,000 0,05788168 0,06082857 ! meiotic cell cycle GO:0051321 75 73 0,000 0,05788168 0,06081068 ! negative regulation of organelle organization GO:0010639 78 73 0,000 0,05788168 0,06079279 ! regulation of protein transport GO:0051223 77 73 0,000 0,05788168 0,06077492 GO:0070201|regulation of establishment of protein localization, ! exopeptidase activity GO:0008238 78 73 0,000 0,05788168 0,06075705 ! cytosolic calcium ion homeostasis GO:0051480 78 73 0,000 0,05788168 0,0607392 ! hormone receptor binding GO:0051427 75 73 0,000 0,05788168 0,06072136 ! nucleosome organization GO:0034728 76 74 0,000 0,05865281 0,06151224 ! neuropeptide signaling pathway GO:0007218 79 74 0,000 0,05865281 0,06149418 ! pore complex GO:0046930 78 74 0,000 0,05865281 0,06147613 ! protein localization in nucleus GO:0034504 78 74 0,000 0,05865281 0,06145809 ! myofibril GO:0030016 80 74 0,000 0,05865281 0,06144006 ! regulation of blood pressure GO:0008217 76 74 0,000 0,05865281 0,06142204 ! apical junction complex GO:0043296 74 74 0,000 0,05865281 0,06140404 ! cellular carbohydrate catabolic process GO:0044275 75 74 0,000 0,05865281 0,06138604 ! development of primary sexual characteristics GO:0045137 74 74 0,000 0,05865281 0,06136805 ! membrane raft GO:0045121 78 74 0,000 0,05865281 0,06135008 ! cellular response to hormone stimulus GO:0032870 81 74 0,000 0,05865281 0,06133211 ! serine-type endopeptidase inhibitor activity GO:0004867 75 74 0,000 0,05865281 0,06131416 ! nuclear chromosome part GO:0044454 76 74 0,000 0,05865281 0,06129622 ! response to drug GO:0042493 77 75 0,000 0,05942335 0,06208332 ! small GTPase binding GO:0031267 78 75 0,000 0,05942335 0,06206516 ! regulation of catabolic process GO:0009894 80 75 0,000 0,05942335 0,06204701 ! cell-substrate junction GO:0030055 82 75 0,000 0,05942335 0,06202887 ! positive regulation of cell activation GO:0050867 80 75 0,000 0,05942335 0,06201075 GO:0002696|positive regulation of leukocyte activation, ! membrane lipid biosynthetic process GO:0046467 77 75 0,000 0,05942335 0,06199263 ! tube morphogenesis GO:0035239 79 75 0,000 0,05942335 0,06197453 ! cellular lipid catabolic process GO:0044242 77 75 0,000 0,05942335 0,06195643 ! cysteine-type endopeptidase activity GO:0004197 75 75 0,000 0,05942335 0,06193835 ! structural constituent of cytoskeleton GO:0005200 81 75 0,000 0,05942335 0,06192027 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 76 76 0,000 0,06019331 0,0627043 ! regulation of ligase activity GO:0051340 78 76 0,000 0,06019331 0,06268601 ! vitamin metabolic process GO:0006766 77 76 0,000 0,06019331 0,06266773 ! inorganic anion transport GO:0015698 78 76 0,000 0,06019331 0,06264947 ! chromosome, centromeric region GO:0000775 78 76 0,000 0,06019331 0,06263121 ! apicolateral plasma membrane GO:0016327 76 76 0,000 0,06019331 0,06261297 ! T cell activation GO:0042110 82 76 0,000 0,06019331 0,06259474 ! digestion GO:0007586 80 76 0,000 0,06019331 0,06257651 ! cell-substrate adhesion GO:0031589 81 76 0,000 0,06019331 0,0625583 ! cilium GO:0005929 77 76 0,000 0,06019331 0,0625401 ! contractile fiber part GO:0044449 82 76 0,000 0,06019331 0,06252191 ! regulation of adenylate cyclase activity GO:0045761 80 77 0,000 0,0609627 0,06330265 ! nuclear speck GO:0016607 80 77 0,000 0,0609627 0,06328425 ! G-protein-coupled receptor binding GO:0001664 78 77 0,000 0,0609627 0,06326586 ! regulation of transmission of nerve impulse GO:0051969 79 77 0,000 0,0609627 0,06324747 ! hydrogen ion transmembrane transporter activity GO:0015078 78 77 0,000 0,0609627 0,0632291 ! vacuolar part GO:0044437 78 77 0,000 0,0609627 0,06321075 ! thiolester hydrolase activity GO:0016790 81 78 0,000 0,06173151 0,06398933 ! potassium channel complex GO:0034705 81 78 0,000 0,06173151 0,06397076 GO:0008076|voltage-gated potassium channel complex, ! blood coagulation GO:0007596 81 78 0,000 0,06173151 0,0639522 GO:0050817|coagulation, ! phospholipid biosynthetic process GO:0008654 83 79 0,000 0,06249974 0,06472929 ! biogenic amine metabolic process GO:0006576 85 79 0,000 0,06249974 0,06471052 ! phosphoric diester hydrolase activity GO:0008081 82 79 0,000 0,06249974 0,06469176 ! regulation of cyclase activity GO:0031279 82 79 0,000 0,06249974 0,06467302 ! regulation of neuron differentiation GO:0045664 82 79 0,000 0,06249974 0,06465428 ! regulation of T cell activation GO:0050863 84 79 0,000 0,06249974 0,06463556 ! regulation of cAMP biosynthetic process GO:0030817 82 79 0,000 0,06249974 0,06461685 ! exocytosis GO:0006887 81 79 0,000 0,06249974 0,06459814 ! nitrogen compound catabolic process GO:0044270 89 79 0,000 0,06249974 0,06457945 ! regulation of protein localization GO:0032880 83 79 0,000 0,06249974 0,06456077 ! alcohol catabolic process GO:0046164 83 80 0,000 0,0632674 0,06533484 ! GTPase binding GO:0051020 83 80 0,000 0,0632674 0,06531596 ! regulation of cell cycle process GO:0010564 84 80 0,000 0,0632674 0,06529708 ! negative regulation of growth GO:0045926 84 80 0,000 0,0632674 0,06527821 ! regulation of lyase activity GO:0051339 83 80 0,000 0,0632674 0,06525936 ! ATP biosynthetic process GO:0006754 85 80 0,000 0,0632674 0,06524051 ! one-carbon metabolic process GO:0006730 87 80 0,000 0,0632674 0,06522168 ! monooxygenase activity GO:0004497 82 80 0,000 0,0632674 0,06520285 ! condensed chromosome GO:0000793 82 80 0,000 0,0632674 0,06518404 ! contractile fiber GO:0043292 86 80 0,000 0,0632674 0,06516524 ! protein ubiquitination GO:0016567 86 80 0,000 0,0632674 0,06514645 ! cellular carbohydrate biosynthetic process GO:0034637 83 81 0,000 0,06403448 0,06591731 ! sterol metabolic process GO:0016125 83 81 0,000 0,06403448 0,06589831 ! regulation of cAMP metabolic process GO:0030814 84 81 0,000 0,06403448 0,06587932 ! protein binding, bridging GO:0030674 86 81 0,000 0,06403448 0,06586035 ! regulation of neurological system process GO:0031644 83 81 0,000 0,06403448 0,06584139 ! protein transporter activity GO:0008565 85 82 0,000 0,06480099 0,06661034 ! positive regulation of immune response GO:0050778 91 82 0,000 0,06480099 0,06659117 ! regulation of defense response GO:0031347 82 82 0,000 0,06480099 0,06657201 ! carboxylesterase activity GO:0004091 86 82 0,000 0,06480099 0,06655287 ! transcription initiation GO:0006352 86 82 0,000 0,06480099 0,06653373 ! organelle outer membrane GO:0031968 87 83 0,000 0,06556691 0,06730079 ! SH3 domain binding GO:0017124 97 83 0,000 0,06556691 0,06728145 ! hemostasis GO:0007599 86 83 0,000 0,06556691 0,06726212 ! oxidative phosphorylation GO:0006119 83 83 0,000 0,06556691 0,06724281 ! heparin binding GO:0008201 90 83 0,000 0,06556691 0,0672235 ! amine transport GO:0015837 83 83 0,000 0,06556691 0,0672042 ! phosphoinositide binding GO:0035091 90 83 0,000 0,06556691 0,06718492 ! regulation of nucleotide biosynthetic process GO:0030808 87 84 0,000 0,06633227 0,06794966 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 85 84 0,000 0,06633227 0,06793018 GO:0010498|proteasomal protein catabolic process, ! Ras GTPase activator activity GO:0005099 89 84 0,000 0,06633227 0,0679107 ! regulation of membrane potential GO:0042391 92 84 0,000 0,06633227 0,06789124 ! perinuclear region of cytoplasm GO:0048471 91 85 0,000 0,06709705 0,06865431 ! cellular respiration GO:0045333 85 85 0,000 0,06709705 0,06863465 ! transmembrane receptor protein kinase activity GO:0019199 88 85 0,000 0,06709705 0,06861499 ! outer membrane GO:0019867 89 85 0,000 0,06709705 0,06859535 ! DNA recombination GO:0006310 86 85 0,000 0,06709705 0,06857572 ! neurotransmitter receptor activity GO:0030594 86 85 0,000 0,06709705 0,0685561 ! leukocyte differentiation GO:0002521 95 86 0,000 0,06786125 0,06931709 ! Golgi vesicle transport GO:0048193 86 86 0,000 0,06786125 0,06929726 ! pigment granule GO:0048770 90 86 0,000 0,06786125 0,06927745 GO:0042470|melanosome, ! neurotransmitter binding GO:0042165 88 86 0,000 0,06786125 0,06925765 ! anion binding GO:0043168 89 86 0,000 0,06786125 0,06923787 ! sex differentiation GO:0007548 86 86 0,000 0,06786125 0,06921809 ! UDP-glycosyltransferase activity GO:0008194 91 86 0,000 0,06786125 0,06919832 ! spindle GO:0005819 89 87 0,000 0,06862488 0,06995702 ! microtubule cytoskeleton organization GO:0000226 92 87 0,000 0,06862488 0,06993706 ! cell cycle arrest GO:0007050 92 87 0,000 0,06862488 0,06991711 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 93 87 0,000 0,06862488 0,06989716 ! regulation of cyclic nucleotide metabolic process GO:0030799 90 87 0,000 0,06862488 0,06987723 ! protein processing GO:0016485 92 87 0,000 0,06862488 0,06985731 ! ATP-dependent helicase activity GO:0008026 92 88 0,000 0,06938794 0,07061394 GO:0070035|purine NTP-dependent helicase activity, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 89 88 0,000 0,06938794 0,07059383 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 89 88 0,000 0,06938794 0,07057372 ! skeletal muscle tissue development GO:0007519 92 88 0,000 0,06938794 0,07055363 GO:0060538|skeletal muscle organ development, ! lipase activity GO:0016298 92 88 0,000 0,06938794 0,07053354 ! detection of stimulus GO:0051606 90 88 0,000 0,06938794 0,07051347 ! carboxylic acid catabolic process GO:0046395 93 89 0,000 0,07015042 0,07126804 GO:0016054|organic acid catabolic process, ! regulation of binding GO:0051098 93 90 0,000 0,07091234 0,0720216 ! intermediate filament GO:0005882 92 90 0,000 0,07091234 0,07200112 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 95 90 0,000 0,07091234 0,07198066 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! external side of plasma membrane GO:0009897 99 90 0,000 0,07091234 0,0719602 ! regulation of nucleotide metabolic process GO:0006140 93 90 0,000 0,07091234 0,07193976 ! adherens junction GO:0005912 96 90 0,000 0,07091234 0,07191933 ! ATP metabolic process GO:0046034 96 91 0,000 0,07167367 0,07267084 ! homophilic cell adhesion GO:0007156 93 91 0,000 0,07167367 0,07265021 ! ribonucleoside triphosphate biosynthetic process GO:0009201 97 91 0,000 0,07167367 0,0726296 ! protein modification by small protein conjugation GO:0032446 98 91 0,000 0,07167367 0,07260899 ! forebrain development GO:0030900 95 91 0,000 0,07167367 0,0725884 ! carbohydrate biosynthetic process GO:0016051 93 91 0,000 0,07167367 0,07256782 ! apical plasma membrane GO:0016324 96 91 0,000 0,07167367 0,07254725 ! intermediate filament cytoskeleton GO:0045111 93 91 0,000 0,07167367 0,07252669 ! angiogenesis GO:0001525 95 92 0,000 0,07243444 0,07327575 ! glycerophospholipid metabolic process GO:0006650 98 92 0,000 0,07243444 0,073255 ! nucleoside triphosphate biosynthetic process GO:0009142 98 92 0,000 0,07243444 0,07323426 ! clathrin-coated vesicle GO:0030136 100 92 0,000 0,07243444 0,07321353 ! protein tyrosine phosphatase activity GO:0004725 104 92 0,000 0,07243444 0,07319281 ! gland development GO:0048732 95 92 0,000 0,07243444 0,07317211 ! DNA packaging GO:0006323 94 92 0,000 0,07243444 0,07315141 ! anatomical structure homeostasis GO:0060249 96 93 0,000 0,07319464 0,07389823 ! receptor complex GO:0043235 97 93 0,000 0,07319464 0,07387735 ! voltage-gated potassium channel activity GO:0005249 99 93 0,000 0,07319464 0,07385647 ! hormone metabolic process GO:0042445 96 93 0,000 0,07319464 0,07383561 ! translational elongation GO:0006414 97 94 0,000 0,07395426 0,07458082 ! nucleotidyltransferase activity GO:0016779 96 94 0,000 0,07395426 0,07455976 ! metalloendopeptidase activity GO:0004222 105 94 0,000 0,07395426 0,07453872 ! carbohydrate catabolic process GO:0016052 95 94 0,000 0,07395426 0,07451768 ! protein maturation GO:0051604 99 94 0,000 0,07395426 0,07449666 ! solute:cation symporter activity GO:0015294 95 94 0,000 0,07395426 0,07447565 ! regulation of lymphocyte activation GO:0051249 100 95 0,000 0,07471332 0,07521885 ! carboxylic acid binding GO:0031406 99 95 0,000 0,07471332 0,07519765 ! response to virus GO:0009615 102 95 0,000 0,07471332 0,07517646 ! peroxisome GO:0005777 97 96 0,000 0,0754718 0,07591825 GO:0042579|microbody, ! integral to organelle membrane GO:0031301 96 96 0,000 0,0754718 0,07589687 ! Wnt receptor signaling pathway GO:0016055 104 96 0,000 0,0754718 0,07587551 ! translation factor activity, nucleic acid binding GO:0008135 99 96 0,000 0,0754718 0,07585415 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 97 96 0,000 0,0754718 0,07583281 ! cell fate commitment GO:0045165 98 96 0,000 0,0754718 0,07581148 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 101 97 0,000 0,07622971 0,07655127 ! microtubule associated complex GO:0005875 104 97 0,000 0,07622971 0,07652975 ! peptidyl-amino acid modification GO:0018193 99 97 0,000 0,07622971 0,07650824 ! anchoring junction GO:0070161 103 97 0,000 0,07622971 0,07648674 ! reproductive developmental process GO:0003006 97 97 0,000 0,07622971 0,07646525 ! unfolded protein binding GO:0051082 100 98 0,000 0,07698706 0,07720325 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 99 98 0,000 0,07698706 0,07718158 ! polysaccharide metabolic process GO:0005976 102 98 0,000 0,07698706 0,07715992 ! protein modification by small protein conjugation or removal GO:0070647 105 98 0,000 0,07698706 0,07713827 ! nuclear chromosome GO:0000228 102 99 0,000 0,07774383 0,07787468 ! anterior/posterior pattern formation GO:0009952 102 99 0,000 0,07774383 0,07785284 ! Ras protein signal transduction GO:0007265 105 99 0,000 0,07774383 0,07783101 ! tRNA metabolic process GO:0006399 101 100 0,000 0,07850004 0,07856604 ! protein polymerization GO:0051258 114 100 0,000 0,07850004 0,07854403 ! cytokine binding GO:0019955 101 100 0,000 0,07850004 0,07852203 ! regulation of cell morphogenesis GO:0022604 104 100 0,000 0,07850004 0,07850004