pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/890-10-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of viral reproduction GO:0048524 5 5 1,000 9,742E-06 0,03553885 ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 9,742E-06 0,01776942 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 2,000 1,066E-05 0,01296492 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 1,46E-05 0,013319 ! DNA topoisomerase activity GO:0003916 6 6 1,000 1,46E-05 0,0106552 ! G2/M transition checkpoint GO:0031576 24 6 1,000 1,46E-05 8,879E-03 GO:0031572|G2/M transition DNA damage checkpoint, ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 2,000 1,79E-05 9,328E-03 ! pronucleus GO:0045120 25 7 1,000 2,043E-05 9,318E-03 ! DNA topological change GO:0006265 7 7 1,000 2,043E-05 8,282E-03 ! DNA ligation GO:0006266 8 7 1,000 2,043E-05 7,454E-03 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 1,000 2,723E-05 9,03E-03 ! centriole GO:0005814 11 11 1,000 5,339E-05 0,01622957 ! regulation of viral genome replication GO:0045069 13 11 1,000 5,339E-05 0,01498114 ! histone deacetylase binding GO:0042826 11 11 1,000 5,339E-05 0,01391106 ! protein kinase C binding GO:0005080 11 11 1,000 5,339E-05 0,01298365 ! midbody GO:0030496 14 12 1,000 6,403E-05 0,01459777 ! interphase of mitotic cell cycle GO:0051329 100 81 2,000 7,194E-05 0,01543686 ! histone deacetylation GO:0016575 14 13 1,000 7,562E-05 0,01532575 ! interphase GO:0051325 103 83 2,000 7,737E-05 0,01485498 ! regulation of viral reproduction GO:0050792 16 14 1,000 8,817E-05 0,0160823 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 1,000 8,817E-05 0,01531647 ! protein kinase binding GO:0019901 115 89 2,000 9,526E-05 0,01579599 ! protein amino acid deacetylation GO:0006476 19 18 1,000 1,479E-04 0,02345571 ! spindle microtubule GO:0005876 27 18 1,000 1,479E-04 0,02247839 ! cellular response to unfolded protein GO:0034620 21 19 1,000 1,652E-04 0,0241034 GO:0030968|endoplasmic reticulum unfolded protein response, ! chromosome condensation GO:0030261 20 19 1,000 1,652E-04 0,02317634 ! histone deacetylase activity GO:0004407 20 19 1,000 1,652E-04 0,02231796 GO:0033558|protein deacetylase activity, ! apoptotic nuclear changes GO:0030262 24 21 1,000 2,026E-04 0,02639719 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 1,000 2,026E-04 0,02548694 ! ubiquitin binding GO:0043130 25 21 1,000 2,026E-04 0,02463737 ! deacetylase activity GO:0019213 23 22 1,000 2,227E-04 0,02621101 ! growth cone GO:0030426 27 24 1,000 2,658E-04 0,0303017 ! small conjugating protein binding GO:0032182 29 24 1,000 2,658E-04 0,02938346 ! site of polarized growth GO:0030427 28 25 1,000 2,887E-04 0,03098042 ! histone deacetylase complex GO:0000118 29 26 1,000 3,126E-04 0,03258348 ! response to endoplasmic reticulum stress GO:0034976 30 26 1,000 3,126E-04 0,03167839 ! fat cell differentiation GO:0045444 30 27 1,000 3,374E-04 0,03326785 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 3,374E-04 0,03239238 ! DNA damage checkpoint GO:0000077 48 28 1,000 3,632E-04 0,03396908 ! ER-nuclear signaling pathway GO:0006984 32 29 1,000 3,898E-04 0,03555166 ! response to calcium ion GO:0051592 34 31 1,000 4,459E-04 0,03967686 ! drug binding GO:0008144 34 31 1,000 4,459E-04 0,03873218 ! DNA integrity checkpoint GO:0031570 51 31 1,000 4,459E-04 0,03783143 ! microtubule organizing center part GO:0044450 46 32 1,000 4,754E-04 0,03941255 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 1,000 5,057E-04 0,04099814 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 5,37E-04 0,04258778 ! nucleus organization GO:0006997 42 36 1,000 6,023E-04 0,04675168 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 1,000 6,023E-04 0,04577769 ! DNA-dependent ATPase activity GO:0008094 63 39 1,000 7,072E-04 0,05264881 ! Notch signaling pathway GO:0007219 46 41 1,000 7,816E-04 0,05702758 ! protein serine/threonine phosphatase activity GO:0004722 45 42 1,000 8,202E-04 0,05866936 ! positive regulation of cell cycle GO:0045787 56 43 1,000 8,597E-04 0,0603115 ! histone modification GO:0016570 45 43 1,000 8,597E-04 0,05917355 ! covalent chromatin modification GO:0016569 47 45 1,000 9,414E-04 0,06359631 ! response to UV GO:0009411 59 45 1,000 9,414E-04 0,06244001 ! chromatin remodeling complex GO:0016585 54 48 1,000 1,071E-03 0,0697467 ! DNA damage response, signal transduction GO:0042770 84 50 1,000 1,161E-03 0,07432564 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 1,000 1,161E-03 0,07304416 ! chromosome segregation GO:0007059 92 57 1,000 1,507E-03 0,09315807 ! cell cycle checkpoint GO:0000075 91 60 1,000 1,668E-03 0,10140844 ! response to metal ion GO:0010038 65 60 1,000 1,668E-03 0,09974601 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 1,000 1,78E-03 0,10471936 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 1,000 1,78E-03 0,10305714 ! response to unfolded protein GO:0006986 66 64 1,000 1,895E-03 0,10802214 ! response to inorganic substance GO:0010035 71 65 1,000 1,954E-03 0,10967048 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 1,000 1,954E-03 0,10800881 ! protein kinase regulator activity GO:0019887 74 66 1,000 2,014E-03 0,10965535 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 1,000 2,075E-03 0,11129989 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 1,000 2,136E-03 0,11294243 ! positive regulation of ligase activity GO:0051351 86 70 1,000 2,262E-03 0,11788181 ! positive regulation of phosphorylation GO:0042327 82 70 1,000 2,262E-03 0,1162215 ! response to protein stimulus GO:0051789 73 70 1,000 2,262E-03 0,11460731 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 1,000 2,391E-03 0,11949258 GO:0045937|positive regulation of phosphate metabolic process, ! phosphoinositide-mediated signaling GO:0048015 92 74 1,000 2,524E-03 0,12441452 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 1,000 2,591E-03 0,12604267 ! kinase regulator activity GO:0019207 93 76 1,000 2,66E-03 0,12766881 ! regulation of ligase activity GO:0051340 95 78 1,000 2,799E-03 0,13261526 ! positive regulation of protein modification process GO:0031401 100 78 1,000 2,799E-03 0,13091506 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 1,000 3,162E-03 0,14603344 GO:0010498|proteasomal protein catabolic process, ! protein tyrosine phosphatase activity GO:0004725 109 89 1,000 3,626E-03 0,16534716 ! spindle GO:0005819 126 92 1,000 3,869E-03 0,17424956 ! cell cycle arrest GO:0007050 103 93 1,000 3,952E-03 0,17580137 ! DNA packaging GO:0006323 113 94 1,000 4,035E-03 0,17735191 ! perinuclear region of cytoplasm GO:0048471 125 97 1,000 4,29E-03 0,18632899 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 1,000 4,553E-03 0,19540996 ! response to light stimulus GO:0009416 131 100 1,000 4,553E-03 0,19313775 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 5,065E-03 0,21238218 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 5,065E-03 0,20996874 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 5,065E-03 0,20760954 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 5,065E-03 0,20530277 ! response to superoxide GO:0000303 5 5 0,000 5,065E-03 0,2030467 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 5,065E-03 0,20083967 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 5,065E-03 0,1986801 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 5,065E-03 0,19656648 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 5,065E-03 0,19449736 ! quinolinate metabolic process GO:0046874 5 5 0,000 5,065E-03 0,19247135 ! biotin binding GO:0009374 7 5 0,000 5,065E-03 0,19048711 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 5,065E-03 0,18854336 ! tongue development GO:0043586 6 5 0,000 5,065E-03 0,18663888 ! nose development GO:0043584 5 5 0,000 5,065E-03 0,18477249 ! cell proliferation in forebrain GO:0021846 5 5 0,000 5,065E-03 0,18294306 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 5,065E-03 0,1811495 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 5,065E-03 0,17939077 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 5,065E-03 0,17766586 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 5,065E-03 0,1759738 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 5,065E-03 0,17431367 ! glycolipid transport GO:0046836 6 5 0,000 5,065E-03 0,17268457 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 5,065E-03 0,17108564 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 5,065E-03 0,16951605 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 5,065E-03 0,16797499 ! neuron adhesion GO:0007158 5 5 0,000 5,065E-03 0,16646171 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 5,065E-03 0,16497544 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 5,065E-03 0,16351548 ! opioid peptide activity GO:0001515 6 5 0,000 5,065E-03 0,16208113 ! selenocysteine incorporation GO:0001514 5 5 0,000 5,065E-03 0,16067173 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 5,065E-03 0,15928663 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 5,065E-03 0,15792521 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 5,065E-03 0,15658686 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 5,065E-03 0,155271 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 5,065E-03 0,15397708 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,065E-03 0,15270454 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 5,065E-03 0,15145286 ! clathrin coat assembly GO:0048268 6 5 0,000 5,065E-03 0,15022154 ! cerebral cortex cell migration GO:0021795 5 5 0,000 5,065E-03 0,14901008 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 5,065E-03 0,14781799 ! membrane hyperpolarization GO:0060081 5 5 0,000 5,065E-03 0,14664484 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 5,065E-03 0,14549015 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 5,065E-03 0,14435351 ! translation repressor activity GO:0030371 8 5 0,000 5,065E-03 0,14323449 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 5,065E-03 0,14213269 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 5,065E-03 0,1410477 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 5,065E-03 0,13997916 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 5,065E-03 0,13892669 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 5,065E-03 0,13788992 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 5,065E-03 0,13686851 ! negative regulation of heart contraction GO:0045822 5 5 0,000 5,065E-03 0,13586213 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 5,065E-03 0,13487043 ! microfibril GO:0001527 5 5 0,000 5,065E-03 0,13389311 ! troponin I binding GO:0031013 5 5 0,000 5,065E-03 0,13292985 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 5,065E-03 0,13198035 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 5,065E-03 0,13104432 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 5,065E-03 0,13012147 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 5,065E-03 0,12921153 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 5,065E-03 0,12831423 ! protein lipoylation GO:0009249 14 5 0,000 5,065E-03 0,12742931 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,065E-03 0,1265565 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 5,065E-03 0,12569557 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 5,065E-03 0,12484628 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 5,065E-03 0,12400838 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 5,065E-03 0,12318166 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 5,065E-03 0,12236589 ! glutamate catabolic process GO:0006538 6 5 0,000 5,065E-03 0,12156085 ! microvillus organization GO:0032528 5 5 0,000 5,065E-03 0,12076634 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 5,065E-03 0,11998214 ! tyrosine catabolic process GO:0006572 5 5 0,000 5,065E-03 0,11920806 ! response to pH GO:0009268 5 5 0,000 5,065E-03 0,11844391 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 5,065E-03 0,11768949 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 5,065E-03 0,11694462 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 5,065E-03 0,11620912 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,065E-03 0,11548281 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 5,065E-03 0,11476552 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,065E-03 0,11405709 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 5,065E-03 0,11335736 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 5,065E-03 0,11266615 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 5,065E-03 0,11198333 ! anaerobic glycolysis GO:0019642 5 5 0,000 5,065E-03 0,11130873 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 5,065E-03 0,11064221 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 5,065E-03 0,10998363 ! peroxisomal matrix GO:0005782 5 5 0,000 5,065E-03 0,10933284 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 5,065E-03 0,1086897 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 5,065E-03 0,10805409 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 5,065E-03 0,10742587 ! multivesicular body GO:0005771 5 5 0,000 5,065E-03 0,10680491 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 5,065E-03 0,10619109 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 5,065E-03 0,10558428 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 5,065E-03 0,10498437 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 5,065E-03 0,10439124 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 5,065E-03 0,10380477 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 5,065E-03 0,10322486 ! epithelial cell maturation GO:0002070 14 5 0,000 5,065E-03 0,10265139 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 5,065E-03 0,10208425 ! muscle thin filament assembly GO:0030240 5 5 0,000 5,065E-03 0,10152335 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 5,065E-03 0,10096858 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 5,065E-03 0,10041983 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 0,000 5,065E-03 0,09987702 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 5,065E-03 0,09934005 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,065E-03 0,09880882 ! positive regulation of translational initiation GO:0045948 6 5 0,000 5,065E-03 0,09828324 ! nonhomologous end joining complex GO:0070419 6 5 0,000 5,065E-03 0,09776322 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 5,065E-03 0,09724868 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 5,065E-03 0,09673953 ! ATPase activator activity GO:0001671 5 5 0,000 5,065E-03 0,09623567 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 5,065E-03 0,09573704 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 0,000 5,065E-03 0,09524355 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 5,065E-03 0,09475512 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 5,065E-03 0,09427168 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 5,065E-03 0,09379314 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 5,065E-03 0,09331944 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 5,065E-03 0,0928505 ! cardiac myofibril assembly GO:0055003 5 5 0,000 5,065E-03 0,09238625 ! anterograde axon cargo transport GO:0008089 6 5 0,000 5,065E-03 0,09192661 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,065E-03 0,09147153 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 5,065E-03 0,09102093 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 5,065E-03 0,09057475 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 5,065E-03 0,09013292 ! protein localization to telomere GO:0070198 7 5 0,000 5,065E-03 0,08969539 ! response to exogenous dsRNA GO:0043330 5 5 0,000 5,065E-03 0,08926207 ! MutSalpha complex binding GO:0032407 7 5 0,000 5,065E-03 0,08883293 ! bile acid biosynthetic process GO:0006699 5 5 0,000 5,065E-03 0,08840789 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 5,065E-03 0,0879869 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 5,065E-03 0,0875699 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,065E-03 0,08715684 ! nerve growth factor binding GO:0048406 7 5 0,000 5,065E-03 0,08674765 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 5,065E-03 0,08634229 ! high-density lipoprotein binding GO:0008035 6 5 0,000 5,065E-03 0,08594069 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 5,065E-03 0,08554282 ! transcription initiation factor activity GO:0016986 5 5 0,000 5,065E-03 0,08514861 ! gas homeostasis GO:0033483 5 5 0,000 5,065E-03 0,08475802 ! Schwann cell development GO:0014044 5 5 0,000 5,065E-03 0,084371 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 5,065E-03 0,0839875 ! cyclohydrolase activity GO:0019238 5 5 0,000 5,065E-03 0,08360746 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,065E-03 0,08323085 ! response to pheromone GO:0019236 5 5 0,000 5,065E-03 0,08285762 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 5,065E-03 0,08248772 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 5,065E-03 0,08212111 ! rhombomere development GO:0021546 6 5 0,000 5,065E-03 0,08175774 ! alanine transport GO:0032328 6 5 0,000 5,065E-03 0,08139757 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 5,065E-03 0,08104057 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 5,065E-03 0,08068668 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 5,065E-03 0,08033587 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 5,065E-03 0,07998809 ! regulation of meiosis GO:0040020 6 5 0,000 5,065E-03 0,07964332 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 5,065E-03 0,0793015 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 5,065E-03 0,0789626 ! lymphocyte costimulation GO:0031294 5 5 0,000 5,065E-03 0,07862659 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 5,065E-03 0,07829343 ! RS domain binding GO:0050733 6 5 0,000 5,065E-03 0,07796308 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 5,065E-03 0,0776355 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 5,065E-03 0,07731067 ! B cell homeostasis GO:0001782 6 5 0,000 5,065E-03 0,07698854 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 5,065E-03 0,07666908 ! anaphase GO:0051322 7 5 0,000 5,065E-03 0,07635227 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 5,065E-03 0,07603806 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 5,065E-03 0,07572643 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 5,065E-03 0,07541734 ! AP-2 adaptor complex GO:0030122 5 5 0,000 5,065E-03 0,07511077 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 5,065E-03 0,07480668 ! diuresis GO:0030146 5 5 0,000 5,065E-03 0,07450504 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 5,065E-03 0,07420582 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 5,065E-03 0,073909 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 5,065E-03 0,07361454 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 5,065E-03 0,07332242 ! GTP-Rho binding GO:0017049 5 5 0,000 5,065E-03 0,07303261 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 5,065E-03 0,07274508 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,065E-03 0,0724598 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 5,065E-03 0,07217676 ! brown fat cell differentiation GO:0050873 5 5 0,000 5,065E-03 0,07189591 ! regulation of telomerase activity GO:0051972 6 5 0,000 5,065E-03 0,07161725 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 5,065E-03 0,07134073 ! TAP complex GO:0042825 5 5 0,000 5,065E-03 0,07106634 ! platelet dense granule GO:0042827 6 5 0,000 5,065E-03 0,07079406 ! bHLH transcription factor binding GO:0043425 5 5 0,000 5,065E-03 0,07052385 ! secretory granule organization GO:0033363 5 5 0,000 5,065E-03 0,0702557 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 5,065E-03 0,06998958 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 5,065E-03 0,06972547 ! lamin binding GO:0005521 8 5 0,000 5,065E-03 0,06946334 ! aldehyde-lyase activity GO:0016832 6 5 0,000 5,065E-03 0,06920318 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,065E-03 0,06894496 ! neural plate morphogenesis GO:0001839 6 5 0,000 5,065E-03 0,06868866 ! cyclosporin A binding GO:0016018 6 5 0,000 5,065E-03 0,06843426 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 5,065E-03 0,06818173 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 5,065E-03 0,06793106 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 5,065E-03 0,06768223 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 5,065E-03 0,06743522 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 5,065E-03 0,06719 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 5,065E-03 0,06694656 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 5,065E-03 0,06670487 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 5,065E-03 0,06646493 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 5,065E-03 0,0662267 ! organ or tissue specific immune response GO:0002251 6 5 0,000 5,065E-03 0,06599018 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 5,065E-03 0,06575534 ! retina homeostasis GO:0001895 5 5 0,000 5,065E-03 0,06552216 ! prepulse inhibition GO:0060134 8 5 0,000 5,065E-03 0,06529063 ! maternal placenta development GO:0001893 5 5 0,000 5,065E-03 0,06506074 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 5,065E-03 0,06483245 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 5,065E-03 0,06460577 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 5,065E-03 0,06438066 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 5,065E-03 0,06415712 ! protein palmitoylation GO:0018345 5 5 0,000 5,065E-03 0,06393512 ! protein amino acid prenylation GO:0018346 6 5 0,000 5,065E-03 0,06371465 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 5,065E-03 0,0634957 ! stem cell division GO:0017145 6 5 0,000 5,065E-03 0,06327825 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 5,065E-03 0,06306228 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 5,065E-03 0,06284779 ! organ regeneration GO:0031100 6 5 0,000 5,065E-03 0,06263474 ! lymphocyte apoptosis GO:0070227 6 5 0,000 5,065E-03 0,06242314 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 5,065E-03 0,06221296 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 5,065E-03 0,06200419 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 5,065E-03 0,06179682 ! acyl carrier activity GO:0000036 5 5 0,000 5,065E-03 0,06159083 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 5,065E-03 0,06138621 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 5,065E-03 0,06118294 ! phagocytic vesicle GO:0045335 5 5 0,000 5,065E-03 0,06098102 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 5,065E-03 0,06078043 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 5,065E-03 0,06058115 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 5,065E-03 0,06038317 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 5,065E-03 0,06018648 ! polyol transport GO:0015791 8 5 0,000 5,065E-03 0,05999107 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 5,065E-03 0,05979692 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 5,065E-03 0,05960403 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 5,065E-03 0,05941238 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 5,065E-03 0,05922195 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 5,065E-03 0,05903275 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 5,065E-03 0,05884474 ! ethanol metabolic process GO:0006067 6 5 0,000 5,065E-03 0,05865793 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 5,065E-03 0,05847231 ! cobalt ion transport GO:0006824 5 5 0,000 5,065E-03 0,05828785 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 5,065E-03 0,05810456 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 5,065E-03 0,05792241 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 5,065E-03 0,0577414 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 5,065E-03 0,05756152 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 5,065E-03 0,05738276 ! sterol carrier activity GO:0005498 6 5 0,000 5,065E-03 0,05720511 ! adaptation of signaling pathway GO:0022401 6 5 0,000 5,065E-03 0,05702855 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 5,065E-03 0,05685307 ! response to acid GO:0001101 7 5 0,000 5,065E-03 0,05667868 ! fibril organization GO:0043206 5 5 0,000 5,065E-03 0,05650535 ! malate metabolic process GO:0006108 6 5 0,000 5,065E-03 0,05633308 ! regulation of dopamine uptake GO:0051584 7 5 0,000 5,065E-03 0,05616185 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 5,065E-03 0,05599166 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 5,065E-03 0,05582251 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 5,065E-03 0,05565437 ! protein maturation by protein folding GO:0022417 5 5 0,000 5,065E-03 0,05548724 ! activation of protein kinase B activity GO:0032148 15 5 0,000 5,065E-03 0,05532111 ! origin recognition complex GO:0000808 5 5 0,000 5,065E-03 0,05515597 ! neurexin binding GO:0042043 6 5 0,000 5,065E-03 0,05499181 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 5,065E-03 0,05482863 ! protein amino acid dealkylation GO:0008214 5 5 0,000 5,065E-03 0,05466642 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 5,065E-03 0,05450516 ! lipoic acid binding GO:0031405 5 5 0,000 5,065E-03 0,05434485 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 5,065E-03 0,05418548 ! lithium ion binding GO:0031403 6 5 0,000 5,065E-03 0,05402704 ! grooming behavior GO:0007625 7 5 0,000 5,065E-03 0,05386953 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 5,065E-03 0,05371293 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 5,065E-03 0,05355724 ! lymph vessel development GO:0001945 6 5 0,000 5,065E-03 0,05340245 ! bicarbonate transport GO:0015701 5 5 0,000 5,065E-03 0,05324856 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 0,000 5,065E-03 0,05309554 GO:0010811|positive regulation of cell-substrate adhesion, ! response to interferon-gamma GO:0034341 6 5 0,000 5,065E-03 0,05294341 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 5,065E-03 0,05279214 ! endothelial cell proliferation GO:0001935 8 5 0,000 5,065E-03 0,05264174 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 5,065E-03 0,05249219 ! dorsal spinal cord development GO:0021516 6 5 0,000 5,065E-03 0,05234348 ! activation of MAPKKK activity GO:0000185 5 5 0,000 5,065E-03 0,05219562 ! synaptic vesicle maturation GO:0016188 6 5 0,000 5,065E-03 0,05204859 ! sphingoid catabolic process GO:0046521 5 5 0,000 5,065E-03 0,05190239 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 5,065E-03 0,051757 ! neutrophil mediated immunity GO:0002446 5 5 0,000 5,065E-03 0,05161243 ! intercellular canaliculus GO:0046581 5 5 0,000 5,065E-03 0,05146866 ! dopamine binding GO:0035240 7 5 0,000 5,065E-03 0,05132569 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 5,065E-03 0,05118352 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 5,065E-03 0,05104213 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 5,065E-03 0,05090151 ! amine oxidase activity GO:0008131 7 5 0,000 5,065E-03 0,05076167 ! monocyte activation GO:0042117 9 5 0,000 5,065E-03 0,0506226 ! negative regulation of protein binding GO:0032091 5 5 0,000 5,065E-03 0,05048429 ! regulation of response to food GO:0032095 5 5 0,000 5,065E-03 0,05034673 ! response to food GO:0032094 6 5 0,000 5,065E-03 0,05020992 ! positive regulation of protein binding GO:0032092 5 5 0,000 5,065E-03 0,05007385 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 5,065E-03 0,04993851 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 5,065E-03 0,04980391 ! hedgehog receptor activity GO:0008158 5 5 0,000 5,065E-03 0,04967003 ! lipoprotein catabolic process GO:0042159 5 5 0,000 5,065E-03 0,04953686 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 5,065E-03 0,04940441 ! purine salvage GO:0043101 7 5 0,000 5,065E-03 0,04927266 ! small-subunit processome GO:0032040 5 5 0,000 5,065E-03 0,04914162 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 5,065E-03 0,04901127 ! ciliary rootlet GO:0035253 5 5 0,000 5,065E-03 0,04888161 ! myosin heavy chain binding GO:0032036 5 5 0,000 5,065E-03 0,04875264 ! nucleobase transport GO:0015851 5 5 0,000 5,065E-03 0,04862434 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 5,065E-03 0,04849672 ! GPI anchor binding GO:0034235 6 5 0,000 5,065E-03 0,04836976 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,065E-03 0,04824347 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 5,065E-03 0,04811784 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 5,065E-03 0,04799286 ! basic amino acid transport GO:0015802 5 5 0,000 5,065E-03 0,04786852 ! dendritic shaft GO:0043198 5 5 0,000 5,065E-03 0,04774483 ! terminal button GO:0043195 7 5 0,000 5,065E-03 0,04762178 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 5,065E-03 0,04749936 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 5,065E-03 0,04737756 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 5,065E-03 0,04725639 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 5,065E-03 0,04713584 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 5,065E-03 0,0470159 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 5,065E-03 0,04689657 ! response to UV-C GO:0010225 15 5 0,000 5,065E-03 0,04677785 ! positive regulation of organ growth GO:0046622 5 5 0,000 5,065E-03 0,04665972 ! response to arsenic GO:0046685 6 5 0,000 5,065E-03 0,04654219 ! IgE binding GO:0019863 5 5 0,000 5,065E-03 0,04642525 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 5,065E-03 0,0463089 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 5,065E-03 0,04619312 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 5,065E-03 0,04607793 ! response to copper ion GO:0046688 5 5 0,000 5,065E-03 0,04596331 ! response to cadmium ion GO:0046686 5 5 0,000 5,065E-03 0,04584925 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 5,065E-03 0,04573577 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 5,065E-03 0,04562284 ! protein autoprocessing GO:0016540 6 5 0,000 5,065E-03 0,04551047 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 5,065E-03 0,04539865 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 5,065E-03 0,04528738 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 5,065E-03 0,04517665 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 5,065E-03 0,04506646 ! mitotic recombination GO:0006312 15 5 0,000 5,065E-03 0,04495681 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 5,065E-03 0,04484769 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,065E-03 0,0447391 ! membrane to membrane docking GO:0022614 5 5 0,000 5,065E-03 0,04463104 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 5,065E-03 0,04452349 ! translation activator activity GO:0008494 5 5 0,000 5,065E-03 0,04441646 ! somatostatin receptor activity GO:0004994 5 5 0,000 5,065E-03 0,04430995 ! melanocortin receptor activity GO:0004977 6 5 0,000 5,065E-03 0,04420395 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 5,065E-03 0,04409845 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 5,065E-03 0,04399345 ! salivary gland morphogenesis GO:0007435 5 5 0,000 5,065E-03 0,04388895 ! galactosidase activity GO:0015925 5 5 0,000 5,065E-03 0,04378495 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 5,065E-03 0,04368144 ! cellular response to nutrient GO:0031670 5 5 0,000 5,065E-03 0,04357842 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 5,065E-03 0,04347588 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 5,065E-03 0,04337382 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 5,065E-03 0,04327225 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 5,065E-03 0,04317114 ! A band GO:0031672 5 5 0,000 5,065E-03 0,04307051 ! heat generation GO:0031649 5 5 0,000 5,065E-03 0,04297035 ! flagellum organization GO:0043064 5 5 0,000 5,065E-03 0,04287065 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 5,065E-03 0,04277141 ! disaccharide metabolic process GO:0005984 6 5 0,000 5,065E-03 0,04267263 ! glycogen catabolic process GO:0005980 16 5 0,000 5,065E-03 0,04257431 ! dopamine biosynthetic process GO:0042416 6 5 0,000 5,065E-03 0,04247644 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 5,065E-03 0,04237901 ! chromocenter GO:0010369 5 5 0,000 5,065E-03 0,04228204 ! glial cell migration GO:0008347 5 5 0,000 5,065E-03 0,0421855 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 5,065E-03 0,04208941 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 5,065E-03 0,04199375 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 5,065E-03 0,04189852 ! growth hormone receptor binding GO:0005131 5 5 0,000 5,065E-03 0,04180373 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 5,065E-03 0,04170937 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 5,065E-03 0,04161543 ! aminomethyltransferase activity GO:0004047 5 5 0,000 5,065E-03 0,04152191 ! aminoacylase activity GO:0004046 5 5 0,000 5,065E-03 0,04142881 ! penetration of zona pellucida GO:0007341 6 5 0,000 5,065E-03 0,04133613 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 5,065E-03 0,04124386 ! nucleus localization GO:0051647 5 5 0,000 5,065E-03 0,041152 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 5,065E-03 0,04106055 ! carnitine metabolic process GO:0009437 5 5 0,000 5,065E-03 0,04096951 GO:0006577|betaine metabolic process, ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,075E-03 0,04903107 ! regulation of helicase activity GO:0051095 6 6 0,000 6,075E-03 0,04892283 ! response to oxygen radical GO:0000305 6 6 0,000 6,075E-03 0,04881507 ! positive regulation of axon extension GO:0045773 7 6 0,000 6,075E-03 0,04870779 ! forebrain neuron differentiation GO:0021879 6 6 0,000 6,075E-03 0,04860097 ! forebrain regionalization GO:0021871 7 6 0,000 6,075E-03 0,04849463 ! meiotic prophase I GO:0007128 7 6 0,000 6,075E-03 0,04838874 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 6,075E-03 0,04828332 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 6,075E-03 0,04817836 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,075E-03 0,04807385 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 6,075E-03 0,04796979 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 6,075E-03 0,04786619 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 6,075E-03 0,04776303 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 6,075E-03 0,04766031 ! protein amino acid sulfation GO:0006477 9 6 0,000 6,075E-03 0,04755803 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 6,075E-03 0,0474562 ! establishment of tissue polarity GO:0007164 8 6 0,000 6,075E-03 0,04735479 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 6,075E-03 0,04725383 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 6,075E-03 0,04715329 ! embryonic camera-type eye development GO:0031076 9 6 0,000 6,075E-03 0,04705317 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 6,075E-03 0,04695348 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 6,075E-03 0,04685422 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 6,075E-03 0,04675537 ! Notch receptor processing GO:0007220 7 6 0,000 6,075E-03 0,04665693 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 6,075E-03 0,04655892 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 6,075E-03 0,04646131 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 6,075E-03 0,04636411 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 6,075E-03 0,04626732 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 6,075E-03 0,04617093 ! neurofilament GO:0005883 7 6 0,000 6,075E-03 0,04607494 ! glial cell fate commitment GO:0021781 7 6 0,000 6,075E-03 0,04597934 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 6,075E-03 0,04588415 ! dynactin complex GO:0005869 7 6 0,000 6,075E-03 0,04578935 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 6,075E-03 0,04569494 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 6,075E-03 0,04560091 ! oocyte maturation GO:0001556 6 6 0,000 6,075E-03 0,04550728 ! DNA replication origin binding GO:0003688 6 6 0,000 6,075E-03 0,04541402 ! reflex GO:0060004 10 6 0,000 6,075E-03 0,04532115 ! positive regulation of glycolysis GO:0045821 6 6 0,000 6,075E-03 0,04522866 ! parathyroid gland development GO:0060017 6 6 0,000 6,075E-03 0,04513655 ! anagen GO:0042640 7 6 0,000 6,075E-03 0,0450448 ! protein-cofactor linkage GO:0018065 15 6 0,000 6,075E-03 0,04495344 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 6,075E-03 0,04486244 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 6,075E-03 0,04477181 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 6,075E-03 0,04468154 ! skeletal myofibril assembly GO:0014866 6 6 0,000 6,075E-03 0,04459164 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 6,075E-03 0,0445021 ! cysteine metabolic process GO:0006534 7 6 0,000 6,075E-03 0,04441291 ! glycine catabolic process GO:0006546 6 6 0,000 6,075E-03 0,04432409 ! adenohypophysis development GO:0021984 6 6 0,000 6,075E-03 0,04423562 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 6,075E-03 0,0441475 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 6,075E-03 0,04405973 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 6,075E-03 0,04397231 ! microtubule nucleation GO:0007020 7 6 0,000 6,075E-03 0,04388524 ! proline biosynthetic process GO:0006561 8 6 0,000 6,075E-03 0,04379851 ! tryptophan metabolic process GO:0006568 6 6 0,000 6,075E-03 0,04371212 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 6,075E-03 0,04362607 ! thyroid hormone generation GO:0006590 6 6 0,000 6,075E-03 0,04354036 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 6,075E-03 0,04345499 ! retinoid X receptor binding GO:0046965 7 6 0,000 6,075E-03 0,04336995 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 6,075E-03 0,04328524 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 6,075E-03 0,04320087 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,075E-03 0,04311682 ! sister chromatid cohesion GO:0007062 6 6 0,000 6,075E-03 0,0430331 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 6,075E-03 0,0429497 ! positive regulation of transporter activity GO:0032411 8 6 0,000 6,075E-03 0,04286662 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 6,075E-03 0,04278387 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 6,075E-03 0,04270143 ! p53 binding GO:0002039 6 6 0,000 6,075E-03 0,04261932 ! demethylase activity GO:0032451 6 6 0,000 6,075E-03 0,04253751 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 6,075E-03 0,04245602 ! regulation of platelet activation GO:0010543 7 6 0,000 6,075E-03 0,04237485 ! lipid phosphatase activity GO:0042577 7 6 0,000 6,075E-03 0,04229398 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 6,075E-03 0,04221342 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 6,075E-03 0,04213316 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 6,075E-03 0,04205321 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 6,075E-03 0,04197357 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 6,075E-03 0,04189422 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 6,075E-03 0,04181518 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 6,075E-03 0,04173643 ! LIM domain binding GO:0030274 7 6 0,000 6,075E-03 0,04165798 ! negative regulation of translational initiation GO:0045947 6 6 0,000 6,075E-03 0,04157982 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 6,075E-03 0,04150196 ! 5S class rRNA transcription GO:0042791 6 6 0,000 6,075E-03 0,04142438 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 6,075E-03 0,0413471 ! axon guidance receptor activity GO:0008046 6 6 0,000 6,075E-03 0,0412701 ! zinc ion homeostasis GO:0055069 7 6 0,000 6,075E-03 0,04119339 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 6,075E-03 0,04111696 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 6,075E-03 0,04104082 ! protein targeting to lysosome GO:0006622 6 6 0,000 6,075E-03 0,04096496 ! hyaluronan metabolic process GO:0030212 8 6 0,000 6,075E-03 0,04088938 ! protein retention in ER lumen GO:0006621 6 6 0,000 6,075E-03 0,04081408 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 6,075E-03 0,04073905 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 6,075E-03 0,0406643 ! dynein binding GO:0045502 6 6 0,000 6,075E-03 0,04058982 ! regulation of dendrite development GO:0050773 6 6 0,000 6,075E-03 0,04051562 ! peptidyl-arginine modification GO:0018195 6 6 0,000 6,075E-03 0,04044169 ! eating behavior GO:0042755 7 6 0,000 6,075E-03 0,04036802 ! protein localization to chromosome GO:0034502 8 6 0,000 6,075E-03 0,04029463 ! Hsp90 protein binding GO:0051879 7 6 0,000 6,075E-03 0,0402215 ! glycolipid binding GO:0051861 7 6 0,000 6,075E-03 0,04014863 ! MutLalpha complex binding GO:0032405 8 6 0,000 6,075E-03 0,04007603 ! mast cell activation GO:0045576 6 6 0,000 6,075E-03 0,04000369 ! regulation of focal adhesion formation GO:0051893 6 6 0,000 6,075E-03 0,03993161 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,075E-03 0,03985979 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 6,075E-03 0,03978823 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 6,075E-03 0,03971692 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 6,075E-03 0,03964587 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 6,075E-03 0,03957508 ! lipoxygenase activity GO:0016165 6 6 0,000 6,075E-03 0,03950453 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 6,075E-03 0,03943424 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 6,075E-03 0,0393642 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 6,075E-03 0,0392944 ! DNA replication factor C complex GO:0005663 7 6 0,000 6,075E-03 0,03922486 ! DNA replication factor A complex GO:0005662 7 6 0,000 6,075E-03 0,03915555 ! establishment of chromosome localization GO:0051303 15 6 0,000 6,075E-03 0,0390865 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 6,075E-03 0,03901768 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 6,075E-03 0,03894911 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 6,075E-03 0,03888078 ! chromatin assembly complex GO:0005678 16 6 0,000 6,075E-03 0,03881269 ! sex chromatin GO:0001739 6 6 0,000 6,075E-03 0,03874483 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 6,075E-03 0,03867721 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 6,075E-03 0,03860983 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 6,075E-03 0,03854269 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 6,075E-03 0,03847577 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 6,075E-03 0,03840909 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 6,075E-03 0,03834264 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 6,075E-03 0,03827641 ! phosphatidylserine binding GO:0001786 6 6 0,000 6,075E-03 0,03821042 ! alpha-mannosidase activity GO:0004559 8 6 0,000 6,075E-03 0,03814465 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 6,075E-03 0,03807911 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 6,075E-03 0,0380138 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 6,075E-03 0,03794871 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 6,075E-03 0,03788384 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 6,075E-03 0,03781919 ! leading edge membrane GO:0031256 8 6 0,000 6,075E-03 0,03775476 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 6,075E-03 0,03769055 ! CARD domain binding GO:0050700 6 6 0,000 6,075E-03 0,03762656 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 6,075E-03 0,03756279 ! COPII vesicle coat GO:0030127 7 6 0,000 6,075E-03 0,03749923 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 6,075E-03 0,03743589 ! glutathione biosynthetic process GO:0006750 7 6 0,000 6,075E-03 0,03737276 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 6,075E-03 0,03730984 ! positive regulation of epidermis development GO:0045684 8 6 0,000 6,075E-03 0,03724713 ! proteasome regulator activity GO:0010860 6 6 0,000 6,075E-03 0,03718464 ! ceramidase activity GO:0017040 6 6 0,000 6,075E-03 0,03712235 ! antibiotic transport GO:0042891 7 6 0,000 6,075E-03 0,03706027 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 6,075E-03 0,0369984 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 6,075E-03 0,03693674 ! sodium channel regulator activity GO:0017080 6 6 0,000 6,075E-03 0,03687528 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 6,075E-03 0,03681403 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 6,075E-03 0,03675298 ! response to fluid shear stress GO:0034405 6 6 0,000 6,075E-03 0,03669213 ! lymph node development GO:0048535 6 6 0,000 6,075E-03 0,03663148 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 6,075E-03 0,03657103 ! triglyceride catabolic process GO:0019433 15 6 0,000 6,075E-03 0,03651078 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 6,075E-03 0,03645073 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 6,075E-03 0,03639088 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 6,075E-03 0,03633122 ! negative regulation of lipase activity GO:0060192 6 6 0,000 6,075E-03 0,03627176 ! activation of innate immune response GO:0002218 6 6 0,000 6,075E-03 0,03621249 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 6,075E-03 0,03615342 ! sarcoglycan complex GO:0016012 8 6 0,000 6,075E-03 0,03609453 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 6,075E-03 0,03603584 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 6,075E-03 0,03597734 ! neural plate development GO:0001840 7 6 0,000 6,075E-03 0,03591903 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 6,075E-03 0,03586091 ! catecholamine transport GO:0051937 6 6 0,000 6,075E-03 0,03580298 ! ether hydrolase activity GO:0016803 7 6 0,000 6,075E-03 0,03574523 ! FACIT collagen GO:0005593 6 6 0,000 6,075E-03 0,03568767 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 6,075E-03 0,0356303 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 6,075E-03 0,0355731 ! collagen type IV GO:0005587 6 6 0,000 6,075E-03 0,0355161 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 6,075E-03 0,03545927 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 6,075E-03 0,03540263 ! drug metabolic process GO:0017144 6 6 0,000 6,075E-03 0,03534616 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 6,075E-03 0,03528988 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 6,075E-03 0,03523377 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 6,075E-03 0,03517785 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 6,075E-03 0,0351221 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 6,075E-03 0,03506653 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 6,075E-03 0,03501113 ! cellular anion homeostasis GO:0030002 6 6 0,000 6,075E-03 0,03495591 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 6,075E-03 0,03490086 ! negative regulation of protein ubiquitination GO:0031397 7 6 0,000 6,075E-03 0,03484598 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 6,075E-03 0,03479128 ! behavioral response to cocaine GO:0048148 9 6 0,000 6,075E-03 0,03473675 ! translation initiation factor binding GO:0031369 6 6 0,000 6,075E-03 0,03468239 ! nucleotide-sugar transport GO:0015780 6 6 0,000 6,075E-03 0,03462819 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 6,075E-03 0,03457417 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 6,075E-03 0,03452032 ! quaternary ammonium group binding GO:0050997 7 6 0,000 6,075E-03 0,03446663 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 6,075E-03 0,03441311 ! reproductive behavior GO:0019098 8 6 0,000 6,075E-03 0,03435976 ! response to growth hormone stimulus GO:0060416 7 6 0,000 6,075E-03 0,03430657 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 6,075E-03 0,03425355 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 6,075E-03 0,03420069 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 6,075E-03 0,03414799 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 6,075E-03 0,03409545 ! induction of positive chemotaxis GO:0050930 7 6 0,000 6,075E-03 0,03404308 ! cohesin complex GO:0008278 6 6 0,000 6,075E-03 0,03399087 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 6,075E-03 0,03393881 ! citrate metabolic process GO:0006101 7 6 0,000 6,075E-03 0,03388692 ! myelin sheath GO:0043209 8 6 0,000 6,075E-03 0,03383518 ! phototransduction, visible light GO:0007603 6 6 0,000 6,075E-03 0,0337836 ! opsonization GO:0008228 7 6 0,000 6,075E-03 0,03373218 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 6,075E-03 0,03368092 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 6,075E-03 0,03362981 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 6,075E-03 0,03357885 ! regulation of potassium ion transport GO:0043266 8 6 0,000 6,075E-03 0,03352805 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 6,075E-03 0,03347741 ! chemoattractant activity GO:0042056 6 6 0,000 6,075E-03 0,03342691 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 6,075E-03 0,03337657 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 6,075E-03 0,03332638 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 6,075E-03 0,03327634 ! leukocyte degranulation GO:0043299 6 6 0,000 6,075E-03 0,03322645 ! bile acid and bile salt transport GO:0015721 7 6 0,000 6,075E-03 0,03317671 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 6,075E-03 0,03312712 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 6,075E-03 0,03307768 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 6,075E-03 0,03302838 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 6,075E-03 0,03297923 ! ceramide biosynthetic process GO:0046513 6 6 0,000 6,075E-03 0,03293023 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 6,075E-03 0,03288137 ! activin receptor activity GO:0017002 7 6 0,000 6,075E-03 0,03283266 ! astrocyte differentiation GO:0048708 6 6 0,000 6,075E-03 0,03278409 ! syncytium formation GO:0006949 6 6 0,000 6,075E-03 0,03273566 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 6,075E-03 0,03268738 ! neutrophil activation GO:0042119 6 6 0,000 6,075E-03 0,03263924 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 6,075E-03 0,03259124 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 6,075E-03 0,03254338 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 6,075E-03 0,03249567 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 6,075E-03 0,03244809 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 6,075E-03 0,03240065 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 6,075E-03 0,03235335 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 6,075E-03 0,03230619 ! neuron apoptosis GO:0051402 7 6 0,000 6,075E-03 0,03225916 ! folic acid transport GO:0015884 8 6 0,000 6,075E-03 0,03221227 ! carnitine transport GO:0015879 6 6 0,000 6,075E-03 0,03216552 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 6,075E-03 0,0321189 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 6,075E-03 0,03207242 ! S-methyltransferase activity GO:0008172 6 6 0,000 6,075E-03 0,03202608 ! phospholipase D activity GO:0004630 6 6 0,000 6,075E-03 0,03197986 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 6,075E-03 0,03193378 ! intercalated disc GO:0014704 8 6 0,000 6,075E-03 0,03188783 ! interaction with symbiont GO:0051702 6 6 0,000 6,075E-03 0,03184202 ! IgG binding GO:0019864 6 6 0,000 6,075E-03 0,03179633 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 6,075E-03 0,03175078 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 6,075E-03 0,03170536 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 6,075E-03 0,03166006 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 6,075E-03 0,0316149 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 6,075E-03 0,03156986 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 6,075E-03 0,03152496 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 6,075E-03 0,03148018 ! dendrite morphogenesis GO:0048813 7 6 0,000 6,075E-03 0,03143552 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 6,075E-03 0,031391 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 6,075E-03 0,0313466 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 6,075E-03 0,03130232 ! nucleosome disassembly GO:0006337 7 6 0,000 6,075E-03 0,03125817 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 6,075E-03 0,03121415 ! regulation of mast cell activation GO:0033003 6 6 0,000 6,075E-03 0,03117024 ! tetracycline transporter activity GO:0008493 7 6 0,000 6,075E-03 0,03112647 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 6,075E-03 0,03108281 ! receptor internalization GO:0031623 8 6 0,000 6,075E-03 0,03103928 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 6,075E-03 0,03099587 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 6,075E-03 0,03095258 ! histamine receptor activity GO:0004969 7 6 0,000 6,075E-03 0,03090941 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 6,075E-03 0,03086636 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 6,075E-03 0,03082343 ! protein deubiquitination GO:0016579 6 6 0,000 6,075E-03 0,03078062 ! axonal fasciculation GO:0007413 7 6 0,000 6,075E-03 0,03073793 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 6,075E-03 0,03069535 ! cytidine deaminase activity GO:0004126 6 6 0,000 6,075E-03 0,0306529 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 6,075E-03 0,03061056 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 6,075E-03 0,03056834 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 6,075E-03 0,03052623 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 6,075E-03 0,03048424 ! glycine binding GO:0016594 9 6 0,000 6,075E-03 0,03044237 ! apical protein localization GO:0045176 7 6 0,000 6,075E-03 0,03040061 ! ankyrin binding GO:0030506 6 6 0,000 6,075E-03 0,03035896 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 6,075E-03 0,03031743 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 6,075E-03 0,03027602 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 6,075E-03 0,03023471 ! progesterone metabolic process GO:0042448 6 6 0,000 6,075E-03 0,03019352 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 6,075E-03 0,03015244 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 6,075E-03 0,03011147 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 6,075E-03 0,03007062 ! ATP catabolic process GO:0006200 6 6 0,000 6,075E-03 0,03002987 ! CoA carboxylase activity GO:0016421 6 6 0,000 6,075E-03 0,02998923 ! determination of adult lifespan GO:0008340 6 6 0,000 6,075E-03 0,02994871 ! S-acyltransferase activity GO:0016417 6 6 0,000 6,075E-03 0,02990829 ! somatic stem cell maintenance GO:0035019 6 6 0,000 6,075E-03 0,02986798 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 6,075E-03 0,02982778 ! IkappaB kinase complex GO:0008385 7 6 0,000 6,075E-03 0,02978769 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 6,075E-03 0,02974771 ! store-operated calcium channel activity GO:0015279 6 6 0,000 6,075E-03 0,02970783 ! alkaline phosphatase activity GO:0004035 7 6 0,000 6,075E-03 0,02966806 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 6,075E-03 0,0296284 ! unconventional myosin complex GO:0016461 8 6 0,000 6,075E-03 0,02958884 ! tRNA transcription GO:0009304 7 7 0,000 7,084E-03 0,03445773 ! respiratory burst GO:0045730 7 7 0,000 7,084E-03 0,03441184 ! telencephalon cell migration GO:0022029 8 7 0,000 7,084E-03 0,03436608 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 7,084E-03 0,03432044 ! cation:chloride symporter activity GO:0015377 8 7 0,000 7,084E-03 0,03427493 ! RNA cap binding GO:0000339 8 7 0,000 7,084E-03 0,03422953 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 7,084E-03 0,03418425 ! ephrin receptor binding GO:0046875 9 7 0,000 7,084E-03 0,03413909 ! male meiosis I GO:0007141 7 7 0,000 7,084E-03 0,03409406 ! synapsis GO:0007129 7 7 0,000 7,084E-03 0,03404914 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 7,084E-03 0,03400433 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 7,084E-03 0,03395965 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 7,084E-03 0,03391508 ! signal peptide processing GO:0006465 7 7 0,000 7,084E-03 0,03387063 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 7,084E-03 0,0338263 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 7,084E-03 0,03378208 ! macrophage chemotaxis GO:0048246 7 7 0,000 7,084E-03 0,03373798 ! Golgi cisterna membrane GO:0032580 7 7 0,000 7,084E-03 0,033694 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 7,084E-03 0,03365012 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 7,084E-03 0,03360636 ! smoothened signaling pathway GO:0007224 8 7 0,000 7,084E-03 0,03356272 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 7,084E-03 0,03351919 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 7,084E-03 0,03347577 ! cytoplasmic microtubule GO:0005881 7 7 0,000 7,084E-03 0,03343246 ! Arp2/3 protein complex GO:0005885 8 7 0,000 7,084E-03 0,03338927 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 7,084E-03 0,03334619 ! ATPase binding GO:0051117 8 7 0,000 7,084E-03 0,03330321 ! positive regulation of isotype switching GO:0045830 7 7 0,000 7,084E-03 0,03326035 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 7,084E-03 0,0332176 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 7,084E-03 0,03317496 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 7,084E-03 0,03313243 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,084E-03 0,03309001 ! thymic T cell selection GO:0045061 16 7 0,000 7,084E-03 0,03304769 ! transepithelial chloride transport GO:0030321 7 7 0,000 7,084E-03 0,03300548 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 7,084E-03 0,03296339 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 7,084E-03 0,03292139 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 7,084E-03 0,03287951 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 7,084E-03 0,03283773 ! melanocyte differentiation GO:0030318 8 7 0,000 7,084E-03 0,03279606 ! malate dehydrogenase activity GO:0016615 8 7 0,000 7,084E-03 0,03275449 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 7,084E-03 0,03271303 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 7,084E-03 0,03267167 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 7,084E-03 0,03263042 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 7,084E-03 0,03258927 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 7,084E-03 0,03254823 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 7,084E-03 0,03250729 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 7,084E-03 0,03246645 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 7,084E-03 0,03242571 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 7,084E-03 0,03238508 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 7,084E-03 0,03234455 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 7,084E-03 0,03230412 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 7,084E-03 0,03226379 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 7,084E-03 0,03222356 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 7,084E-03 0,03218343 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 7,084E-03 0,0321434 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 7,084E-03 0,03210347 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 7,084E-03 0,03206364 ! melanosome organization GO:0032438 7 7 0,000 7,084E-03 0,03202391 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 7,084E-03 0,03198428 ! mesodermal cell differentiation GO:0048333 9 7 0,000 7,084E-03 0,03194474 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 7,084E-03 0,0319053 ! Rac protein signal transduction GO:0016601 7 7 0,000 7,084E-03 0,03186596 ! chondrocyte differentiation GO:0002062 7 7 0,000 7,084E-03 0,03182672 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 7,084E-03 0,03178757 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 7,084E-03 0,03174852 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 7,084E-03 0,03170956 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 7,084E-03 0,0316707 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 7,084E-03 0,03163194 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 7,084E-03 0,03159327 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 7,084E-03 0,03155469 ! Schwann cell differentiation GO:0014037 8 7 0,000 7,084E-03 0,03151621 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 7,084E-03 0,03147783 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 7,084E-03 0,03143953 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 7,084E-03 0,03140133 ! vinculin binding GO:0017166 9 7 0,000 7,084E-03 0,03136322 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 7,084E-03 0,03132521 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 7,084E-03 0,03128728 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 7,084E-03 0,03124945 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 7,084E-03 0,03121171 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 7,084E-03 0,03117406 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 7,084E-03 0,0311365 ! cardiac muscle cell development GO:0055013 8 7 0,000 7,084E-03 0,03109903 ! fibrinolysis GO:0042730 9 7 0,000 7,084E-03 0,03106165 ! response to tropane GO:0014073 10 7 0,000 7,084E-03 0,03102436 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 7,084E-03 0,03098716 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 7,084E-03 0,03095005 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 7,084E-03 0,03091303 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 7,084E-03 0,0308761 ! laminin-1 complex GO:0005606 7 7 0,000 7,084E-03 0,03083925 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 7,084E-03 0,0308025 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 7,084E-03 0,03076583 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 7,084E-03 0,03072924 ! regulation of cell division GO:0051302 7 7 0,000 7,084E-03 0,03069275 ! holo TFIIH complex GO:0005675 7 7 0,000 7,084E-03 0,03065634 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 7,084E-03 0,03062002 ! chitinase activity GO:0004568 7 7 0,000 7,084E-03 0,03058378 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 7,084E-03 0,03054763 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 7,084E-03 0,03051156 ! regulation of respiratory burst GO:0060263 8 7 0,000 7,084E-03 0,03047558 ! prophase GO:0051324 8 7 0,000 7,084E-03 0,03043969 ! peptidyl-histidine modification GO:0018202 8 7 0,000 7,084E-03 0,03040388 ! centriolar satellite GO:0034451 10 7 0,000 7,084E-03 0,03036815 ! BBSome GO:0034464 7 7 0,000 7,084E-03 0,03033251 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 7,084E-03 0,03029695 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,084E-03 0,03026147 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 7,084E-03 0,03022608 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 7,084E-03 0,03019076 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 7,084E-03 0,03015554 ! regulation of synaptogenesis GO:0051963 7 7 0,000 7,084E-03 0,03012039 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 7,084E-03 0,03008533 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 7,084E-03 0,03005034 ! glycolipid catabolic process GO:0019377 7 7 0,000 7,084E-03 0,03001544 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 7,084E-03 0,02998062 ! circadian behavior GO:0048512 9 7 0,000 7,084E-03 0,02994588 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 7,084E-03 0,02991122 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 7,084E-03 0,02987664 ! striatum development GO:0021756 7 7 0,000 7,084E-03 0,02984214 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 7,084E-03 0,02980772 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 7,084E-03 0,02977338 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 7,084E-03 0,02973912 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 7,084E-03 0,02970494 ! dystroglycan complex GO:0016011 9 7 0,000 7,084E-03 0,02967083 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 7,084E-03 0,02963681 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 7,084E-03 0,02960286 ! peroxiredoxin activity GO:0051920 7 7 0,000 7,084E-03 0,02956899 ! muscle adaptation GO:0043500 7 7 0,000 7,084E-03 0,02953519 ! regulation of muscle adaptation GO:0043502 7 7 0,000 7,084E-03 0,02950148 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 7,084E-03 0,02946784 ! lysogeny GO:0030069 7 7 0,000 7,084E-03 0,02943428 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 7,084E-03 0,02940079 ! sequestering of metal ion GO:0051238 9 7 0,000 7,084E-03 0,02936738 ! membrane attack complex GO:0005579 7 7 0,000 7,084E-03 0,02933405 ! fibrinogen complex GO:0005577 7 7 0,000 7,084E-03 0,02930079 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 7,084E-03 0,0292676 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 7,084E-03 0,0292345 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 7,084E-03 0,02920146 ! GABA receptor binding GO:0050811 8 7 0,000 7,084E-03 0,0291685 ! sheet-forming collagen GO:0030935 7 7 0,000 7,084E-03 0,02913562 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 7,084E-03 0,02910281 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 7,084E-03 0,02907007 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 7,084E-03 0,02903741 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 7,084E-03 0,02900482 ! 7S RNA binding GO:0008312 8 7 0,000 7,084E-03 0,0289723 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 7,084E-03 0,02893986 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 7,084E-03 0,02890749 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 7,084E-03 0,02887519 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 7,084E-03 0,02884296 ! Golgi to endosome transport GO:0006895 8 7 0,000 7,084E-03 0,02881081 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 7,084E-03 0,02877872 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 7,084E-03 0,02874671 ! fibril GO:0043205 7 7 0,000 7,084E-03 0,02871477 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 7,084E-03 0,0286829 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 7,084E-03 0,0286511 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 7,084E-03 0,02861937 ! sensory perception of bitter taste GO:0050913 7 7 0,000 7,084E-03 0,02858772 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 7,084E-03 0,02855613 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 7,084E-03 0,02852461 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 7,084E-03 0,02849316 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 7,084E-03 0,02846178 ! equilibrioception GO:0050957 10 7 0,000 7,084E-03 0,02843047 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 7,084E-03 0,02839922 ! titin binding GO:0031432 7 7 0,000 7,084E-03 0,02836805 ! chemosensory behavior GO:0007635 9 7 0,000 7,084E-03 0,02833695 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 7,084E-03 0,02830591 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 7,084E-03 0,02827494 ! cobalamin binding GO:0031419 7 7 0,000 7,084E-03 0,02824404 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 7,084E-03 0,0282132 ! response to axon injury GO:0048678 9 7 0,000 7,084E-03 0,02818244 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 7,084E-03 0,02815174 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 7,084E-03 0,0281211 ! F-actin capping protein complex GO:0008290 8 7 0,000 7,084E-03 0,02809054 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 7,084E-03 0,02806004 ! cGMP-mediated signaling GO:0019934 8 7 0,000 7,084E-03 0,0280296 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 7,084E-03 0,02799924 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 7,084E-03 0,02796893 ! senescence GO:0010149 8 7 0,000 7,084E-03 0,0279387 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 7,084E-03 0,02790853 ! nuclear localization sequence binding GO:0008139 8 7 0,000 7,084E-03 0,02787842 ! galactose metabolic process GO:0006012 8 7 0,000 7,084E-03 0,02784838 ! vesicle fusion GO:0006906 8 7 0,000 7,084E-03 0,0278184 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 7,084E-03 0,02778849 ! intracellular pH reduction GO:0051452 7 7 0,000 7,084E-03 0,02775864 ! glycerol ether catabolic process GO:0044269 16 7 0,000 7,084E-03 0,02772886 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 7,084E-03 0,02769914 ! ruffle organization GO:0031529 9 7 0,000 7,084E-03 0,02766948 ! nucleoside transport GO:0015858 8 7 0,000 7,084E-03 0,02763989 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 7,084E-03 0,02761036 ! inclusion body GO:0016234 7 7 0,000 7,084E-03 0,02758089 ! Cajal body GO:0015030 7 7 0,000 7,084E-03 0,02755149 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 7,084E-03 0,02752215 ! rRNA modification GO:0000154 7 7 0,000 7,084E-03 0,02749287 ! PcG protein complex GO:0031519 7 7 0,000 7,084E-03 0,02746365 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 7,084E-03 0,0274345 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 7,084E-03 0,0274054 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 7,084E-03 0,02737637 ! apolipoprotein binding GO:0034185 9 7 0,000 7,084E-03 0,0273474 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 7,084E-03 0,02731849 ! segment specification GO:0007379 9 7 0,000 7,084E-03 0,02728965 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 7,084E-03 0,02726086 ! Rac GTPase activator activity GO:0030675 9 7 0,000 7,084E-03 0,02723213 ! regulation of DNA repair GO:0006282 19 7 0,000 7,084E-03 0,02720347 ! preribosome GO:0030684 7 7 0,000 7,084E-03 0,02717486 ! hair follicle maturation GO:0048820 8 7 0,000 7,084E-03 0,02714632 ! renal water homeostasis GO:0003091 7 7 0,000 7,084E-03 0,02711783 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 7,084E-03 0,02708941 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 7,084E-03 0,02706104 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 7,084E-03 0,02703273 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 7,084E-03 0,02700449 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 7,084E-03 0,0269763 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 7,084E-03 0,02694817 ! phosphofructokinase activity GO:0008443 7 7 0,000 7,084E-03 0,0269201 ! gap junction channel activity GO:0005243 8 7 0,000 7,084E-03 0,02689209 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 7,084E-03 0,02686413 ! histone methylation GO:0016571 7 7 0,000 7,084E-03 0,02683624 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 7,084E-03 0,0268084 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 7,084E-03 0,02678062 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 7,084E-03 0,02675289 ! muscle cell proliferation GO:0033002 8 7 0,000 7,084E-03 0,02672523 ! transcription termination GO:0006353 9 7 0,000 7,084E-03 0,02669762 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 0,000 7,084E-03 0,02667007 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 7,084E-03 0,02664257 ! cytidylyltransferase activity GO:0070567 8 7 0,000 7,084E-03 0,02661513 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 7,084E-03 0,02658775 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 7,084E-03 0,02656043 ! salivary gland development GO:0007431 7 7 0,000 7,084E-03 0,02653316 ! glucosidase activity GO:0015926 8 7 0,000 7,084E-03 0,02650594 ! NuRD complex GO:0016581 8 7 0,000 7,084E-03 0,02647879 ! negative regulation of nuclear division GO:0051784 7 7 0,000 7,084E-03 0,02645168 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 7,084E-03 0,02642464 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 7,084E-03 0,02639765 ! response to redox state GO:0051775 8 7 0,000 7,084E-03 0,02637071 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 7,084E-03 0,02634383 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 7,084E-03 0,026317 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 7,084E-03 0,02629023 ! actin monomer binding GO:0003785 7 7 0,000 7,084E-03 0,02626351 ! protein prenyltransferase activity GO:0008318 8 7 0,000 7,084E-03 0,02623685 ! endosome to lysosome transport GO:0008333 7 7 0,000 7,084E-03 0,02621024 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 7,084E-03 0,02618368 ! germ cell migration GO:0008354 7 7 0,000 7,084E-03 0,02615718 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 7,084E-03 0,02613073 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 7,084E-03 0,02610434 ! CoA-ligase activity GO:0016405 8 7 0,000 7,084E-03 0,026078 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 7,084E-03 0,02605171 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 7,084E-03 0,02602547 ! embryonic heart tube development GO:0035050 8 7 0,000 7,084E-03 0,02599929 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 7,084E-03 0,02597316 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 7,084E-03 0,02594708 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 7,084E-03 0,02592106 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 7,084E-03 0,02589508 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 7,084E-03 0,02586916 ! adenylate kinase activity GO:0004017 8 7 0,000 7,084E-03 0,02584329 ! negative regulation of immune effector process GO:0002698 13 7 0,000 7,084E-03 0,02581748 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 7,084E-03 0,02579171 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 7,084E-03 0,025766 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 8,092E-03 0,02940339 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 8,092E-03 0,02937413 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 8,092E-03 0,02934493 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 8,092E-03 0,02931579 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 0,000 8,092E-03 0,02928671 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 8,092E-03 0,02925768 ! proteasome regulatory particle GO:0005838 8 8 0,000 8,092E-03 0,02922872 ! SMAD protein complex assembly GO:0007183 10 8 0,000 8,092E-03 0,02919981 ! regulation of smooth muscle cell migration GO:0014910 11 8 0,000 8,092E-03 0,02917095 ! protein self-association GO:0043621 8 8 0,000 8,092E-03 0,02914216 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 8,092E-03 0,02911342 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 8,092E-03 0,02908473 ! neurotransmitter uptake GO:0001504 8 8 0,000 8,092E-03 0,02905611 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 8,092E-03 0,02902754 ! guanylate cyclase activity GO:0004383 9 8 0,000 8,092E-03 0,02899902 ! troponin complex GO:0005861 8 8 0,000 8,092E-03 0,02897056 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 8,092E-03 0,02894216 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 8,092E-03 0,02891381 ! keratinocyte proliferation GO:0043616 9 8 0,000 8,092E-03 0,02888552 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 8,092E-03 0,02885729 ! microtubule bundle formation GO:0001578 8 8 0,000 8,092E-03 0,02882911 ! middle ear morphogenesis GO:0042474 10 8 0,000 8,092E-03 0,02880098 ! ganglioside metabolic process GO:0001573 8 8 0,000 8,092E-03 0,02877291 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 8,092E-03 0,02874489 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 8,092E-03 0,02871693 ! ciliary or flagellar motility GO:0001539 8 8 0,000 8,092E-03 0,02868902 ! pathogenesis GO:0009405 8 8 0,000 8,092E-03 0,02866117 ! pH reduction GO:0045851 9 8 0,000 8,092E-03 0,02863337 ! small protein activating enzyme activity GO:0008641 10 8 0,000 8,092E-03 0,02860562 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 8,092E-03 0,02857793 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 8,092E-03 0,02855029 ! hemoglobin metabolic process GO:0020027 8 8 0,000 8,092E-03 0,02852271 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 8,092E-03 0,02849518 ! arginine catabolic process GO:0006527 9 8 0,000 8,092E-03 0,0284677 ! T-tubule GO:0030315 9 8 0,000 8,092E-03 0,02844027 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 8,092E-03 0,0284129 ! histidine catabolic process GO:0006548 8 8 0,000 8,092E-03 0,02838558 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 8,092E-03 0,02835831 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 8,092E-03 0,0283311 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 8,092E-03 0,02830393 ! proline metabolic process GO:0006560 10 8 0,000 8,092E-03 0,02827682 ! L-serine metabolic process GO:0006563 9 8 0,000 8,092E-03 0,02824976 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 8,092E-03 0,02822276 ! melanosome membrane GO:0033162 9 8 0,000 8,092E-03 0,0281958 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 8,092E-03 0,0281689 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 8,092E-03 0,02814204 ! pericentriolar material GO:0000242 9 8 0,000 8,092E-03 0,02811524 ! reverse cholesterol transport GO:0043691 8 8 0,000 8,092E-03 0,02808849 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 8,092E-03 0,02806179 ! melanin metabolic process GO:0006582 10 8 0,000 8,092E-03 0,02803514 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 8,092E-03 0,02800854 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 8,092E-03 0,02798199 ! Golgi lumen GO:0005796 8 8 0,000 8,092E-03 0,0279555 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 8,092E-03 0,02792905 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 8,092E-03 0,02790265 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 8,092E-03 0,0278763 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 8,092E-03 0,02785 ! stereocilium bundle GO:0032421 11 8 0,000 8,092E-03 0,02782375 ! forebrain cell migration GO:0021885 9 8 0,000 8,092E-03 0,02779756 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 8,092E-03 0,02777141 ! osteoblast development GO:0002076 11 8 0,000 8,092E-03 0,0277453 ! retinoic acid metabolic process GO:0042573 8 8 0,000 8,092E-03 0,02771925 ! retinol metabolic process GO:0042572 8 8 0,000 8,092E-03 0,02769325 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 8,092E-03 0,0276673 ! structural constituent of epidermis GO:0030280 9 8 0,000 8,092E-03 0,02764139 ! clathrin binding GO:0030276 10 8 0,000 8,092E-03 0,02761553 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 8,092E-03 0,02758972 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 8,092E-03 0,02756396 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 8,092E-03 0,02753825 ! motor axon guidance GO:0008045 8 8 0,000 8,092E-03 0,02751259 ! protein targeting to vacuole GO:0006623 8 8 0,000 8,092E-03 0,02748697 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 8,092E-03 0,0274614 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 8,092E-03 0,02743588 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 8,092E-03 0,0274104 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 8,092E-03 0,02738498 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 8,092E-03 0,0273596 ! protein-lipid complex assembly GO:0065005 8 8 0,000 8,092E-03 0,02733426 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 8,092E-03 0,02730898 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 8,092E-03 0,02728374 ! regulation of dopamine secretion GO:0014059 9 8 0,000 8,092E-03 0,02725854 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 8,092E-03 0,0272334 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 8,092E-03 0,0272083 ! subpallium development GO:0021544 8 8 0,000 8,092E-03 0,02718324 ! positive regulation of Rho GTPase activity GO:0032321 11 8 0,000 8,092E-03 0,02715824 ! icosanoid secretion GO:0032309 10 8 0,000 8,092E-03 0,02713328 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 8,092E-03 0,02710836 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 8,092E-03 0,02708349 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 8,092E-03 0,02705867 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 8,092E-03 0,02703389 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 8,092E-03 0,02700915 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 8,092E-03 0,02698446 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 8,092E-03 0,02695982 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 8,092E-03 0,02693522 ! ubiquinone metabolic process GO:0006743 9 8 0,000 8,092E-03 0,02691067 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 8,092E-03 0,02688616 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 8,092E-03 0,0268617 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 8,092E-03 0,02683728 ! Wnt receptor activity GO:0042813 11 8 0,000 8,092E-03 0,0268129 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 8,092E-03 0,02678857 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 8,092E-03 0,02676428 ! detection of calcium ion GO:0005513 9 8 0,000 8,092E-03 0,02674004 ! negative regulation of glucose import GO:0046325 9 8 0,000 8,092E-03 0,02671584 ! blastocyst growth GO:0001832 8 8 0,000 8,092E-03 0,02669169 ! regulation of fibrinolysis GO:0051917 8 8 0,000 8,092E-03 0,02666757 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 8,092E-03 0,02664351 ! cerebellar cortex formation GO:0021697 9 8 0,000 8,092E-03 0,02661948 ! complement binding GO:0001848 11 8 0,000 8,092E-03 0,0265955 ! regulation of actin filament bundle formation GO:0032231 13 8 0,000 8,092E-03 0,02657156 GO:0051492|regulation of stress fiber formation, ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 8,092E-03 0,02654767 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 8,092E-03 0,02652381 ! amino sugar catabolic process GO:0046348 8 8 0,000 8,092E-03 0,0265 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 8,092E-03 0,02647624 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 8,092E-03 0,02645251 ! positive regulation of amine transport GO:0051954 9 8 0,000 8,092E-03 0,02642883 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 8,092E-03 0,02640519 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 8,092E-03 0,02638159 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 8,092E-03 0,02635804 ! Golgi transport complex GO:0017119 8 8 0,000 8,092E-03 0,02633453 ! positive regulation of protein ubiquitination GO:0031398 17 8 0,000 8,092E-03 0,02631106 ! GDP binding GO:0019003 9 8 0,000 8,092E-03 0,02628763 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 8,092E-03 0,02626424 ! prostate gland development GO:0030850 17 8 0,000 8,092E-03 0,02624089 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 8,092E-03 0,02621759 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 8,092E-03 0,02619432 ! phosphate transport GO:0006817 9 8 0,000 8,092E-03 0,0261711 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 8,092E-03 0,02614792 ! oligopeptide transport GO:0006857 8 8 0,000 8,092E-03 0,02612478 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 8,092E-03 0,02610168 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 8,092E-03 0,02607863 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 8,092E-03 0,02605561 ! lipoprotein transport GO:0042953 9 8 0,000 8,092E-03 0,02603263 ! estrogen metabolic process GO:0008210 8 8 0,000 8,092E-03 0,0260097 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 8,092E-03 0,0259868 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 8,092E-03 0,02596394 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 8,092E-03 0,02594113 ! T-helper 1 type immune response GO:0042088 8 8 0,000 8,092E-03 0,02591835 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 8,092E-03 0,02589562 ! response to amphetamine GO:0001975 11 8 0,000 8,092E-03 0,02587292 ! mechanosensory behavior GO:0007638 8 8 0,000 8,092E-03 0,02585027 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 8,092E-03 0,02582765 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 8,092E-03 0,02580507 ! C-X-C chemokine binding GO:0019958 8 8 0,000 8,092E-03 0,02578254 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 8,092E-03 0,02576004 ! glycerolipid catabolic process GO:0046503 17 8 0,000 8,092E-03 0,02573758 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 8,092E-03 0,02571516 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 8,092E-03 0,02569278 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 8,092E-03 0,02567044 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 8,092E-03 0,02564814 ! pigment granule organization GO:0048753 9 8 0,000 8,092E-03 0,02562587 ! GTP-dependent protein binding GO:0030742 11 8 0,000 8,092E-03 0,02560365 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 8,092E-03 0,02558146 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 8,092E-03 0,02555931 ! regulation of pigmentation during development GO:0048070 11 8 0,000 8,092E-03 0,0255372 ! macrophage activation GO:0042116 8 8 0,000 8,092E-03 0,02551513 ! poly(A) RNA binding GO:0008143 8 8 0,000 8,092E-03 0,02549309 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 8,092E-03 0,0254711 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 8,092E-03 0,02544914 ! asymmetric protein localization GO:0008105 9 8 0,000 8,092E-03 0,02542722 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 8,092E-03 0,02540534 ! neurotrophin binding GO:0043121 10 8 0,000 8,092E-03 0,02538349 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 8,092E-03 0,02536169 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 8,092E-03 0,02533992 ! phagocytosis, engulfment GO:0006911 10 8 0,000 8,092E-03 0,02531819 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 8,092E-03 0,02529649 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 8,092E-03 0,02527483 ! UV protection GO:0009650 9 8 0,000 8,092E-03 0,02525321 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 8,092E-03 0,02523163 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 8,092E-03 0,02521008 ! glutathione peroxidase activity GO:0004602 17 8 0,000 8,092E-03 0,02518857 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 8,092E-03 0,0251671 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 8,092E-03 0,02514566 ! ferric iron binding GO:0008199 9 8 0,000 8,092E-03 0,02512426 ! response to UV-B GO:0010224 10 8 0,000 8,092E-03 0,02510289 ! intermediate filament organization GO:0045109 8 8 0,000 8,092E-03 0,02508157 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 8,092E-03 0,02506028 ! cellular extravasation GO:0045123 9 8 0,000 8,092E-03 0,02503902 ! skeletal muscle contraction GO:0003009 8 8 0,000 8,092E-03 0,0250178 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 8,092E-03 0,02499662 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 0,000 8,092E-03 0,02497547 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 8,092E-03 0,02495436 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 8,092E-03 0,02493328 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 8,092E-03 0,02491224 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 8,092E-03 0,02489123 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 8,092E-03 0,02487026 ! erythrocyte development GO:0048821 9 8 0,000 8,092E-03 0,02484933 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 8,092E-03 0,02482843 ! ribosome assembly GO:0042255 8 8 0,000 8,092E-03 0,02480757 ! postreplication repair GO:0006301 19 8 0,000 8,092E-03 0,02478674 ! gamma-tubulin binding GO:0043015 8 8 0,000 8,092E-03 0,02476594 ! NADPH oxidase complex GO:0043020 8 8 0,000 8,092E-03 0,02474518 ! mRNA cleavage GO:0006379 9 8 0,000 8,092E-03 0,02472446 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 8,092E-03 0,02470377 ! opioid receptor activity GO:0004985 8 8 0,000 8,092E-03 0,02468311 ! zymogen activation GO:0031638 9 8 0,000 8,092E-03 0,02466249 ! coenzyme A metabolic process GO:0015936 8 8 0,000 8,092E-03 0,02464191 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 8,092E-03 0,02462135 ! costamere GO:0043034 8 8 0,000 8,092E-03 0,02460084 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 8,092E-03 0,02458035 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 8,092E-03 0,0245599 ! sarcomere organization GO:0045214 9 8 0,000 8,092E-03 0,02453949 ! wide pore channel activity GO:0022829 9 8 0,000 8,092E-03 0,02451911 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 8,092E-03 0,02449876 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 8,092E-03 0,02447844 ! hormone catabolic process GO:0042447 9 8 0,000 8,092E-03 0,02445816 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 8,092E-03 0,02443792 ! cGMP biosynthetic process GO:0006182 9 8 0,000 8,092E-03 0,0244177 ! lysozyme activity GO:0003796 10 8 0,000 8,092E-03 0,02439752 ! death receptor binding GO:0005123 8 8 0,000 8,092E-03 0,02437738 ! protein modification by small protein removal GO:0070646 9 8 0,000 8,092E-03 0,02435726 ! adult feeding behavior GO:0008343 9 8 0,000 8,092E-03 0,02433718 ! microtubule basal body GO:0005932 8 8 0,000 8,092E-03 0,02431714 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 8,092E-03 0,02429712 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 8,092E-03 0,02427714 ! calcium-release channel activity GO:0015278 8 8 0,000 8,092E-03 0,02425719 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 8,092E-03 0,02423728 ! behavioral response to nicotine GO:0035095 9 8 0,000 8,092E-03 0,02421739 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 8,092E-03 0,02419754 ! adenosine deaminase activity GO:0004000 8 8 0,000 8,092E-03 0,02417773 ! NAD biosynthetic process GO:0009435 9 8 0,000 8,092E-03 0,02415794 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 9,1E-03 0,02714242 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 9,1E-03 0,02712024 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 9,1E-03 0,0270981 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 9,1E-03 0,027076 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 9,1E-03 0,02705393 ! myotube differentiation GO:0014902 9 9 0,000 9,1E-03 0,0270319 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 9,1E-03 0,02700991 ! N-glycan processing GO:0006491 10 9 0,000 9,1E-03 0,02698795 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 9,1E-03 0,02696602 ! actin-myosin filament sliding GO:0033275 11 9 0,000 9,1E-03 0,02694414 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 9,1E-03 0,02692228 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 9,1E-03 0,02690047 ! RNA methylation GO:0001510 9 9 0,000 9,1E-03 0,02687868 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 9,1E-03 0,02685694 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 9,1E-03 0,02683523 ! artery development GO:0060840 9 9 0,000 9,1E-03 0,02681355 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 9,1E-03 0,02679191 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 9,1E-03 0,0267703 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 9,1E-03 0,02674873 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 9,1E-03 0,02672719 ! positive regulation of heart contraction GO:0045823 11 9 0,000 9,1E-03 0,02670569 ! lipopolysaccharide binding GO:0001530 9 9 0,000 9,1E-03 0,02668422 ! regulated secretory pathway GO:0045055 10 9 0,000 9,1E-03 0,02666279 ! estrogen receptor binding GO:0030331 9 9 0,000 9,1E-03 0,02664139 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 9,1E-03 0,02662003 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 9,1E-03 0,0265987 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 9,1E-03 0,0265774 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 9,1E-03 0,02655614 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 0,000 9,1E-03 0,02653491 ! urea metabolic process GO:0019627 19 9 0,000 9,1E-03 0,02651372 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 9,1E-03 0,02649256 ! autophagic vacuole GO:0005776 11 9 0,000 9,1E-03 0,02647143 ! Rac GTPase binding GO:0048365 10 9 0,000 9,1E-03 0,02645034 ! response to dietary excess GO:0002021 9 9 0,000 9,1E-03 0,02642928 ! regulation of sodium ion transport GO:0002028 10 9 0,000 9,1E-03 0,02640825 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 9,1E-03 0,02638726 ! lens development in camera-type eye GO:0002088 9 9 0,000 9,1E-03 0,0263663 ! male sex determination GO:0030238 9 9 0,000 9,1E-03 0,02634538 ! positive regulation of vasodilation GO:0045909 19 9 0,000 9,1E-03 0,02632449 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 9,1E-03 0,02630363 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 9,1E-03 0,0262828 ! male germ cell nucleus GO:0001673 11 9 0,000 9,1E-03 0,02626201 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 9,1E-03 0,02624125 ! copper ion homeostasis GO:0055070 9 9 0,000 9,1E-03 0,02622052 ! protein heterooligomerization GO:0051291 10 9 0,000 9,1E-03 0,02619982 ! spectrin GO:0008091 9 9 0,000 9,1E-03 0,02617916 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 9,1E-03 0,02615853 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 9,1E-03 0,02613793 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 9,1E-03 0,02611737 ! regulation of B cell differentiation GO:0045577 10 9 0,000 9,1E-03 0,02609684 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 9,1E-03 0,02607634 ! neural tube patterning GO:0021532 10 9 0,000 9,1E-03 0,02605587 ! fucose catabolic process GO:0019317 10 9 0,000 9,1E-03 0,02603543 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 9,1E-03 0,02601503 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 9,1E-03 0,02599466 ! sterol catabolic process GO:0016127 10 9 0,000 9,1E-03 0,02597432 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 9,1E-03 0,02595401 ! clathrin coat of coated pit GO:0030132 11 9 0,000 9,1E-03 0,02593373 ! SNARE complex GO:0031201 11 9 0,000 9,1E-03 0,02591349 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 9,1E-03 0,02589327 ! negative regulation of glucose transport GO:0010829 10 9 0,000 9,1E-03 0,02587309 ! methionine biosynthetic process GO:0009086 11 9 0,000 9,1E-03 0,02585294 ! peptidoglycan binding GO:0042834 9 9 0,000 9,1E-03 0,02583282 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 9,1E-03 0,02581273 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 9,1E-03 0,02579268 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 9,1E-03 0,02577265 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 9,1E-03 0,02575266 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 9,1E-03 0,02573269 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 9,1E-03 0,02571276 ! detection of bacterium GO:0016045 10 9 0,000 9,1E-03 0,02569286 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 9,1E-03 0,02567299 ! embryonic gut development GO:0048566 10 9 0,000 9,1E-03 0,02565315 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 9,1E-03 0,02563334 ! desmosome GO:0030057 10 9 0,000 9,1E-03 0,02561356 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 9,1E-03 0,02559381 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 9,1E-03 0,0255741 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 9,1E-03 0,02555441 ! actin filament polymerization GO:0030041 10 9 0,000 9,1E-03 0,02553475 ! negative regulation of B cell activation GO:0050869 10 9 0,000 9,1E-03 0,02551512 ! establishment of cell polarity GO:0030010 10 9 0,000 9,1E-03 0,02549553 ! regulation of synapse organization GO:0050807 10 9 0,000 9,1E-03 0,02547596 ! septin complex GO:0031105 10 9 0,000 9,1E-03 0,02545642 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 9,1E-03 0,02543692 ! anchoring collagen GO:0030934 9 9 0,000 9,1E-03 0,02541744 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 9,1E-03 0,02539799 ! regulation of developmental growth GO:0048638 11 9 0,000 9,1E-03 0,02537857 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 9,1E-03 0,02535919 ! GMP binding GO:0019002 11 9 0,000 9,1E-03 0,02533983 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 9,1E-03 0,0253205 ! virus-host interaction GO:0019048 13 9 0,000 9,1E-03 0,0253012 ! pentose-phosphate shunt GO:0006098 11 9 0,000 9,1E-03 0,02528193 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 9,1E-03 0,02526269 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 9,1E-03 0,02524348 ! non-recombinational repair GO:0000726 10 9 0,000 9,1E-03 0,0252243 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 9,1E-03 0,02520514 ! nuclear telomere cap complex GO:0000783 10 9 0,000 9,1E-03 0,02518602 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 9,1E-03 0,02516693 ! social behavior GO:0035176 10 9 0,000 9,1E-03 0,02514786 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 9,1E-03 0,02512882 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 9,1E-03 0,02510982 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 9,1E-03 0,02509084 ! mating GO:0007618 11 9 0,000 9,1E-03 0,02507188 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 9,1E-03 0,02505296 ! rhythmic behavior GO:0007622 11 9 0,000 9,1E-03 0,02503407 ! phospholipid efflux GO:0033700 10 9 0,000 9,1E-03 0,0250152 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 9,1E-03 0,02499637 ! poly-purine tract binding GO:0070717 9 9 0,000 9,1E-03 0,02497756 ! T cell proliferation GO:0042098 10 9 0,000 9,1E-03 0,02495878 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 9,1E-03 0,02494003 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 9,1E-03 0,0249213 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 9,1E-03 0,02490261 ! interleukin-1 binding GO:0019966 10 9 0,000 9,1E-03 0,02488394 ! glucosyltransferase activity GO:0046527 9 9 0,000 9,1E-03 0,0248653 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 9,1E-03 0,02484669 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 9,1E-03 0,0248281 ! ovulation GO:0030728 9 9 0,000 9,1E-03 0,02480955 ! acid phosphatase activity GO:0003993 18 9 0,000 9,1E-03 0,02479102 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 9,1E-03 0,02477252 ! ER overload response GO:0006983 11 9 0,000 9,1E-03 0,02475405 ! B cell proliferation GO:0042100 10 9 0,000 9,1E-03 0,0247356 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 9,1E-03 0,02471718 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 9,1E-03 0,02469879 ! mannose metabolic process GO:0006013 13 9 0,000 9,1E-03 0,02468043 ! lipid digestion GO:0044241 11 9 0,000 9,1E-03 0,02466209 ! tumor necrosis factor binding GO:0043120 9 9 0,000 9,1E-03 0,02464378 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 9,1E-03 0,0246255 ! regulation of bone resorption GO:0045124 10 9 0,000 9,1E-03 0,02460725 ! brain morphogenesis GO:0048854 9 9 0,000 9,1E-03 0,02458902 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 9,1E-03 0,02457082 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 9,1E-03 0,02455264 ! synaptic vesicle membrane GO:0030672 9 9 0,000 9,1E-03 0,0245345 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 9,1E-03 0,02451638 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 9,1E-03 0,02449828 ! kinesin binding GO:0019894 9 9 0,000 9,1E-03 0,02448022 ! multicellular organismal aging GO:0010259 18 9 0,000 9,1E-03 0,02446218 ! Ran GTPase binding GO:0008536 11 9 0,000 9,1E-03 0,02444416 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 9,1E-03 0,02442618 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 9,1E-03 0,02440822 ! mRNA polyadenylation GO:0006378 10 9 0,000 9,1E-03 0,02439028 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 9,1E-03 0,02437238 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 9,1E-03 0,02435449 ! prostaglandin receptor activity GO:0004955 11 9 0,000 9,1E-03 0,02433664 ! caspase inhibitor activity GO:0043027 9 9 0,000 9,1E-03 0,02431881 ! adrenoceptor activity GO:0004935 12 9 0,000 9,1E-03 0,02430101 ! regulation of isotype switching GO:0045191 9 9 0,000 9,1E-03 0,02428323 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 9,1E-03 0,02426548 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 9,1E-03 0,02424775 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 9,1E-03 0,02423006 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 9,1E-03 0,02421238 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 9,1E-03 0,02419473 ! Notch binding GO:0005112 10 9 0,000 9,1E-03 0,02417711 ! ATPase regulator activity GO:0060590 10 9 0,000 9,1E-03 0,02415952 ! gamma-tubulin complex GO:0000930 19 9 0,000 9,1E-03 0,02414195 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 9,1E-03 0,0241244 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 9,1E-03 0,02410688 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 9,1E-03 0,02408939 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 9,1E-03 0,02407192 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 0,000 0,01010576 0,02671436 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,01010576 0,02669501 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,01010576 0,0266757 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,01010576 0,02665641 ! sleep GO:0030431 11 10 0,000 0,01010576 0,02663715 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,01010576 0,02661792 ! lipid particle GO:0005811 10 10 0,000 0,01010576 0,02659871 ! filopodium assembly GO:0046847 14 10 0,000 0,01010576 0,02657953 ! UTP metabolic process GO:0046051 12 10 0,000 0,01010576 0,02656038 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,01010576 0,02654126 ! guanylate kinase activity GO:0004385 14 10 0,000 0,01010576 0,02652217 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,01010576 0,0265031 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,01010576 0,02648406 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,01010576 0,02646505 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,01010576 0,02644606 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,01010576 0,02642711 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,01010576 0,02640818 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,01010576 0,02638927 ! lung alveolus development GO:0048286 11 10 0,000 0,01010576 0,0263704 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,01010576 0,02635155 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01010576 0,02633272 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,01010576 0,02631393 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,01010576 0,02629516 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,01010576 0,02627642 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,01010576 0,0262577 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,01010576 0,02623901 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,01010576 0,02622035 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,01010576 0,02620171 ! histidine metabolic process GO:0006547 10 10 0,000 0,01010576 0,02618311 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,01010576 0,02616452 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,01010576 0,02614597 ! death receptor activity GO:0005035 11 10 0,000 0,01010576 0,02612744 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,01010576 0,02610893 ! entry into host cell GO:0030260 11 10 0,000 0,01010576 0,02609045 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,01010576 0,026072 ! filamentous actin GO:0031941 11 10 0,000 0,01010576 0,02605358 ! behavioral fear response GO:0001662 12 10 0,000 0,01010576 0,02603518 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,01010576 0,02601681 ! negative regulation of ossification GO:0030279 12 10 0,000 0,01010576 0,02599846 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,01010576 0,02598014 ! macrophage differentiation GO:0030225 11 10 0,000 0,01010576 0,02596184 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,01010576 0,02594357 ! recycling endosome membrane GO:0055038 11 10 0,000 0,01010576 0,02592533 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,01010576 0,02590711 ! snRNA metabolic process GO:0016073 10 10 0,000 0,01010576 0,02588891 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,01010576 0,02587075 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 0,01010576 0,0258526 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,01010576 0,02583449 ! positive regulation of Ras GTPase activity GO:0032320 14 10 0,000 0,01010576 0,0258164 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,01010576 0,02579833 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,01010576 0,02578029 ! induction of an organ GO:0001759 12 10 0,000 0,01010576 0,02576227 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,01010576 0,02574428 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,01010576 0,02572632 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,01010576 0,02570838 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,01010576 0,02569046 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,01010576 0,02567257 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,01010576 0,02565471 ! ribonuclease P activity GO:0004526 10 10 0,000 0,01010576 0,02563687 ! COPI vesicle coat GO:0030126 12 10 0,000 0,01010576 0,02561905 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,01010576 0,02560126 ! vitamin transporter activity GO:0051183 12 10 0,000 0,01010576 0,02558349 ! snRNA binding GO:0017069 11 10 0,000 0,01010576 0,02556575 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,01010576 0,02554803 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,01010576 0,02553034 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,01010576 0,02551267 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,01010576 0,02549503 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,01010576 0,02547741 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,01010576 0,02545982 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,01010576 0,02544224 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,01010576 0,0254247 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,01010576 0,02540718 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,01010576 0,02538968 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 0,01010576 0,0253722 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 0,01010576 0,02535475 ! extracellular matrix binding GO:0050840 11 10 0,000 0,01010576 0,02533733 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,01010576 0,02531993 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,01010576 0,02530255 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,01010576 0,02528519 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,01010576 0,02526786 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 0,01010576 0,02525056 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,01010576 0,02523327 ! thyroid gland development GO:0030878 12 10 0,000 0,01010576 0,02521601 ! DNA bending activity GO:0008301 11 10 0,000 0,01010576 0,02519878 ! regulation of phosphatase activity GO:0010921 10 10 0,000 0,01010576 0,02518157 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,01010576 0,02516438 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,01010576 0,02514721 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,01010576 0,02513007 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,01010576 0,02511295 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,01010576 0,02509586 ! regulation of glycolysis GO:0006110 11 10 0,000 0,01010576 0,02507878 ! nucleotidase activity GO:0008252 10 10 0,000 0,01010576 0,02506174 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,01010576 0,02504471 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,01010576 0,02502771 ! androgen metabolic process GO:0008209 11 10 0,000 0,01010576 0,02501073 ! lateral plasma membrane GO:0016328 13 10 0,000 0,01010576 0,02499377 ! MAP kinase kinase activity GO:0004708 12 10 0,000 0,01010576 0,02497684 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,01010576 0,02495993 ! startle response GO:0001964 13 10 0,000 0,01010576 0,02494304 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,01010576 0,02492617 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,01010576 0,02490933 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 0,01010576 0,02489251 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,01010576 0,02487572 ! spinal cord patterning GO:0021511 12 10 0,000 0,01010576 0,02485894 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,01010576 0,02484219 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,01010576 0,02482546 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,01010576 0,02480876 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 0,01010576 0,02479207 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,01010576 0,02477541 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,01010576 0,02475877 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,01010576 0,02474216 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,01010576 0,02472556 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,01010576 0,02470899 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,01010576 0,02469244 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,01010576 0,02467591 ! adult heart development GO:0007512 14 10 0,000 0,01010576 0,02465941 ! neuromuscular junction development GO:0007528 12 10 0,000 0,01010576 0,02464292 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,01010576 0,02462646 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,01010576 0,02461002 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,01010576 0,0245936 ! signalosome GO:0008180 10 10 0,000 0,01010576 0,02457721 ! lysophospholipase activity GO:0004622 19 10 0,000 0,01010576 0,02456083 ! prefoldin complex GO:0016272 10 10 0,000 0,01010576 0,02454448 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,01010576 0,02452815 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,01010576 0,02451184 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,01010576 0,02449556 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,01010576 0,02447929 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,01010576 0,02446305 ! gland morphogenesis GO:0022612 11 10 0,000 0,01010576 0,02444683 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,01010576 0,02443062 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,01010576 0,02441445 ! peptide transporter activity GO:0015197 10 10 0,000 0,01010576 0,02439829 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,01010576 0,02438215 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,01010576 0,02436604 ! muscle maintenance GO:0046716 10 10 0,000 0,01010576 0,02434994 ! acid secretion GO:0046717 12 10 0,000 0,01010576 0,02433387 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,01010576 0,02431782 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,01010576 0,02430179 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,01010576 0,02428578 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,01010576 0,02426979 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,01010576 0,02425382 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,01010576 0,02423788 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,01010576 0,02422195 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,01010576 0,02420605 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 0,01010576 0,02419017 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,01010576 0,0241743 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,01010576 0,02415846 ! water channel activity GO:0015250 15 10 0,000 0,01010576 0,02414264 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,01010576 0,02412684 ! regulation of embryonic development GO:0045995 12 10 0,000 0,01010576 0,02411106 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 0,000 0,01010576 0,0240953 ! acrosome reaction GO:0007340 12 10 0,000 0,01010576 0,02407956 ! mitochondrion localization GO:0051646 10 10 0,000 0,01010576 0,02406385 ! cilium part GO:0044441 10 10 0,000 0,01010576 0,02404815 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,011111 0,02642302 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,011111 0,02640581 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,011111 0,02638862 ! cadmium ion binding GO:0046870 15 11 0,000 0,011111 0,02637145 ! hemoglobin complex GO:0005833 13 11 0,000 0,011111 0,0263543 ! CTP metabolic process GO:0046036 13 11 0,000 0,011111 0,02633718 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,011111 0,02632008 ! response to pain GO:0048265 12 11 0,000 0,011111 0,026303 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,011111 0,02628594 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,011111 0,0262689 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,011111 0,02625189 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,011111 0,0262349 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,011111 0,02621793 ! peptide antigen binding GO:0042605 14 11 0,000 0,011111 0,02620098 ! polyamine metabolic process GO:0006595 11 11 0,000 0,011111 0,02618406 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,011111 0,02616715 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,011111 0,02615027 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,011111 0,02613341 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,011111 0,02611657 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,011111 0,02609975 ! protein homotetramerization GO:0051289 13 11 0,000 0,011111 0,02608296 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,011111 0,02606619 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,011111 0,02604943 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,011111 0,0260327 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,011111 0,02601599 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,011111 0,02599931 ! response to dsRNA GO:0043331 21 11 0,000 0,011111 0,02598264 ! response to amine stimulus GO:0014075 15 11 0,000 0,011111 0,025966 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,011111 0,02594937 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,011111 0,02593277 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,011111 0,02591619 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,011111 0,02589963 ! retinal binding GO:0016918 11 11 0,000 0,011111 0,02588309 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,011111 0,02586657 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,011111 0,02585008 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,011111 0,0258336 ! autonomic nervous system development GO:0048483 12 11 0,000 0,011111 0,02581715 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,011111 0,02580071 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,011111 0,0257843 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,011111 0,02576791 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,011111 0,02575154 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,011111 0,02573519 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,011111 0,02571886 ! regulation of epidermis development GO:0045682 14 11 0,000 0,011111 0,02570255 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,011111 0,02568626 ! midbrain development GO:0030901 12 11 0,000 0,011111 0,02566999 ! musculoskeletal movement GO:0050881 12 11 0,000 0,011111 0,02565375 GO:0050879|multicellular organismal movement, ! regulation of RNA stability GO:0043487 13 11 0,000 0,011111 0,02563752 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,011111 0,02562131 ! cell killing GO:0001906 13 11 0,000 0,011111 0,02560513 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,011111 0,02558896 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,011111 0,02557282 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,011111 0,0255567 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 0,011111 0,02554059 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 0,011111 0,02552451 ! folic acid binding GO:0005542 12 11 0,000 0,011111 0,02550844 ! mRNA 3'-end processing GO:0031124 12 11 0,000 0,011111 0,0254924 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,011111 0,02547638 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,011111 0,02546038 ! microspike assembly GO:0030035 15 11 0,000 0,011111 0,02544439 ! lamellipodium assembly GO:0030032 22 11 0,000 0,011111 0,02542843 ! fibrillar collagen GO:0005583 12 11 0,000 0,011111 0,02541249 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,011111 0,02539657 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,011111 0,02538066 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,011111 0,02536478 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,011111 0,02534892 ! synaptonemal complex GO:0000795 11 11 0,000 0,011111 0,02533307 ! reproductive cellular process GO:0048610 13 11 0,000 0,011111 0,02531725 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,011111 0,02530145 ! positive regulation of B cell proliferation GO:0030890 15 11 0,000 0,011111 0,02528566 ! Golgi vesicle budding GO:0048194 12 11 0,000 0,011111 0,0252699 ! response to cAMP GO:0051591 11 11 0,000 0,011111 0,02525415 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,011111 0,02523843 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,011111 0,02522272 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,011111 0,02520704 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,011111 0,02519137 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,011111 0,02517573 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,011111 0,0251601 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 0,011111 0,02514449 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,011111 0,0251289 ! drug transport GO:0015893 12 11 0,000 0,011111 0,02511333 ! FMN binding GO:0010181 12 11 0,000 0,011111 0,02509778 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,011111 0,02508225 ! water transporter activity GO:0005372 17 11 0,000 0,011111 0,02506674 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,011111 0,02505125 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,011111 0,02503577 ! multicellular organism growth GO:0035264 12 11 0,000 0,011111 0,02502032 ! integrator complex GO:0032039 11 11 0,000 0,011111 0,02500489 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,011111 0,02498947 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,011111 0,02497407 ! brush border membrane GO:0031526 12 11 0,000 0,011111 0,02495869 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,011111 0,02494333 ! negative regulation of caspase activity GO:0043154 12 11 0,000 0,011111 0,02492799 ! macroautophagy GO:0016236 12 11 0,000 0,011111 0,02491267 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,011111 0,02489737 ! neuromuscular junction GO:0031594 12 11 0,000 0,011111 0,02488209 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,011111 0,02486682 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 0,011111 0,02485157 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,011111 0,02483635 ! response to antibiotic GO:0046677 13 11 0,000 0,011111 0,02482114 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,011111 0,02480595 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,011111 0,02479078 ! proteasome accessory complex GO:0022624 11 11 0,000 0,011111 0,02477562 ! neuroblast proliferation GO:0007405 13 11 0,000 0,011111 0,02476049 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,011111 0,02474537 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,011111 0,02473027 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,011111 0,02471519 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,011111 0,02470013 ! male genitalia development GO:0030539 15 11 0,000 0,011111 0,02468509 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,011111 0,02467007 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,011111 0,02465506 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,011111 0,02464007 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,011111 0,0246251 ! arylsulfatase activity GO:0004065 12 11 0,000 0,011111 0,02461015 ! sterol transporter activity GO:0015248 11 11 0,000 0,011111 0,02459522 ! response to nicotine GO:0035094 13 11 0,000 0,011111 0,0245803 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,011111 0,02456541 ! rRNA transcription GO:0009303 12 12 0,000 0,01211527 0,02676953 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,01211527 0,02675333 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,01211527 0,02673714 ! superoxide anion generation GO:0042554 12 12 0,000 0,01211527 0,02672098 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,01211527 0,02670483 ! regulation of S phase GO:0033261 16 12 0,000 0,01211527 0,02668871 ! regulation of chemokine production GO:0032642 13 12 0,000 0,01211527 0,0266726 ! male meiosis GO:0007140 12 12 0,000 0,01211527 0,02665651 ! signal complex assembly GO:0007172 15 12 0,000 0,01211527 0,02664044 ! positive regulation of GTPase activity GO:0043547 17 12 0,000 0,01211527 0,0266244 ! GTP metabolic process GO:0046039 14 12 0,000 0,01211527 0,02660837 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,01211527 0,02659236 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,01211527 0,02657637 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,01211527 0,02656039 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,01211527 0,02654444 ! cartilage condensation GO:0001502 14 12 0,000 0,01211527 0,02652851 ! polysome GO:0005844 14 12 0,000 0,01211527 0,0265126 ! hippocampus development GO:0021766 13 12 0,000 0,01211527 0,0264967 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,01211527 0,02648082 ! beta-amyloid binding GO:0001540 12 12 0,000 0,01211527 0,02646497 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,01211527 0,02644913 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,01211527 0,02643331 ! regulation of exit from mitosis GO:0007096 31 12 0,000 0,01211527 0,02641751 ! chylomicron GO:0042627 13 12 0,000 0,01211527 0,02640173 ! T cell selection GO:0045058 22 12 0,000 0,01211527 0,02638597 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,01211527 0,02637022 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,01211527 0,0263545 ! WW domain binding GO:0050699 12 12 0,000 0,01211527 0,02633879 ! methionine metabolic process GO:0006555 14 12 0,000 0,01211527 0,02632311 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,01211527 0,02630744 ! glycine metabolic process GO:0006544 14 12 0,000 0,01211527 0,02629179 ! plasma membrane organization GO:0007009 12 12 0,000 0,01211527 0,02627616 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01211527 0,02626054 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,01211527 0,02624495 ! Golgi organization GO:0007030 15 12 0,000 0,01211527 0,02622937 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01211527 0,02621382 ! mitotic spindle organization GO:0007052 13 12 0,000 0,01211527 0,02619828 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,01211527 0,02618276 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,01211527 0,02616726 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,01211527 0,02615177 ! temperature homeostasis GO:0001659 13 12 0,000 0,01211527 0,02613631 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,01211527 0,02612086 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01211527 0,02610543 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01211527 0,02609002 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,01211527 0,02607463 ! axon cargo transport GO:0008088 13 12 0,000 0,01211527 0,02605925 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,01211527 0,0260439 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,01211527 0,02602856 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,01211527 0,02601324 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,01211527 0,02599794 ! basal lamina GO:0005605 12 12 0,000 0,01211527 0,02598266 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,01211527 0,02596739 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,01211527 0,02595214 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,01211527 0,02593691 ! biomineral formation GO:0031214 14 12 0,000 0,01211527 0,0259217 ! water homeostasis GO:0030104 12 12 0,000 0,01211527 0,0259065 ! promoter binding GO:0010843 14 12 0,000 0,01211527 0,02589133 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,01211527 0,02587617 ! intestinal absorption GO:0050892 14 12 0,000 0,01211527 0,02586103 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,01211527 0,0258459 ! oocyte differentiation GO:0009994 13 12 0,000 0,01211527 0,0258308 ! oxygen transport GO:0015671 13 12 0,000 0,01211527 0,02581571 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,01211527 0,02580064 ! cholesterol efflux GO:0033344 13 12 0,000 0,01211527 0,02578559 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,01211527 0,02577055 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,01211527 0,02575553 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,01211527 0,02574053 ! tropomyosin binding GO:0005523 12 12 0,000 0,01211527 0,02572555 ! blastocyst formation GO:0001825 13 12 0,000 0,01211527 0,02571059 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,01211527 0,02569564 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,01211527 0,02568071 ! mannose binding GO:0005537 13 12 0,000 0,01211527 0,02566579 ! phosphoprotein binding GO:0051219 14 12 0,000 0,01211527 0,0256509 ! defense response to fungus GO:0050832 12 12 0,000 0,01211527 0,02563602 ! embryonic placenta development GO:0001892 16 12 0,000 0,01211527 0,02562116 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01211527 0,02560631 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,01211527 0,02559149 ! acyl-CoA binding GO:0000062 12 12 0,000 0,01211527 0,02557668 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,01211527 0,02556188 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,01211527 0,02554711 ! copper ion transport GO:0006825 12 12 0,000 0,01211527 0,02553235 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,01211527 0,02551761 ! inositol metabolic process GO:0006020 21 12 0,000 0,01211527 0,02550288 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,01211527 0,02548818 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,01211527 0,02547348 ! protein complex disassembly GO:0043241 15 12 0,000 0,01211527 0,02545881 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,01211527 0,02544415 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,01211527 0,02542951 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,01211527 0,02541489 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,01211527 0,02540029 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,01211527 0,0253857 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,01211527 0,02537112 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,01211527 0,02535657 ! endoderm development GO:0007492 13 12 0,000 0,01211527 0,02534203 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,01211527 0,02532751 ! focal adhesion formation GO:0048041 16 12 0,000 0,01211527 0,025313 ! T cell receptor complex GO:0042101 31 12 0,000 0,01211527 0,02529851 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,01211527 0,02528404 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,01211527 0,02526958 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,01211527 0,02525514 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,01211527 0,02524072 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,01211527 0,02522631 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,01211527 0,02521192 ! retinol binding GO:0019841 12 12 0,000 0,01211527 0,02519755 ! regulation of organ growth GO:0046620 12 12 0,000 0,01211527 0,02518319 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,01211527 0,02516885 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,01211527 0,02515452 ! histone acetylation GO:0016573 13 12 0,000 0,01211527 0,02514021 ! ribosome binding GO:0043022 13 12 0,000 0,01211527 0,02512592 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,01211527 0,02511165 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,01211527 0,02509739 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,01211527 0,02508314 ! tissue regeneration GO:0042246 12 12 0,000 0,01211527 0,02506891 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,01211527 0,0250547 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,01211527 0,02504051 ! germ cell nucleus GO:0043073 14 12 0,000 0,01211527 0,02502633 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,01211527 0,02501217 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,01211527 0,02499802 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01211527 0,02498389 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01211527 0,02496977 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,01211527 0,02495567 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,01211527 0,02494159 ! dopamine metabolic process GO:0042417 15 12 0,000 0,01211527 0,02492752 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,01211527 0,02491347 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,01211527 0,02489943 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,01211527 0,02488541 ! bacterial binding GO:0008367 14 12 0,000 0,01211527 0,02487141 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01211527 0,02485742 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,01211527 0,02484345 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,01211527 0,02482949 ! localization within membrane GO:0051668 13 12 0,000 0,01211527 0,02481555 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,01211527 0,02480163 ! axoneme part GO:0044447 12 12 0,000 0,01211527 0,02478772 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01311857 0,02682542 ! neuron maturation GO:0042551 14 13 0,000 0,01311857 0,02681039 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01311857 0,02679538 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01311857 0,02678039 ! bone remodeling GO:0046849 14 13 0,000 0,01311857 0,02676541 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01311857 0,02675045 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01311857 0,0267355 ! striated muscle thin filament GO:0005865 14 13 0,000 0,01311857 0,02672057 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01311857 0,02670566 ! organelle fusion GO:0048284 16 13 0,000 0,01311857 0,02669077 ! palate development GO:0060021 15 13 0,000 0,01311857 0,02667589 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01311857 0,02666103 ! arginine metabolic process GO:0006525 14 13 0,000 0,01311857 0,02664619 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01311857 0,02663136 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01311857 0,02661655 ! response to retinoic acid GO:0032526 17 13 0,000 0,01311857 0,02660175 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01311857 0,02658697 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01311857 0,02657221 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01311857 0,02655746 ! fear response GO:0042596 15 13 0,000 0,01311857 0,02654273 ! epithelial cell development GO:0002064 22 13 0,000 0,01311857 0,02652802 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,01311857 0,02651332 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01311857 0,02649864 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01311857 0,02648398 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01311857 0,02646933 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01311857 0,0264547 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01311857 0,02644008 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,01311857 0,02642548 ! cranial nerve development GO:0021545 15 13 0,000 0,01311857 0,0264109 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,01311857 0,02639633 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01311857 0,02638178 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,01311857 0,02636724 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01311857 0,02635273 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01311857 0,02633822 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01311857 0,02632373 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01311857 0,02630926 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01311857 0,02629481 ! NADP metabolic process GO:0006739 15 13 0,000 0,01311857 0,02628037 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01311857 0,02626594 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01311857 0,02625154 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01311857 0,02623714 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01311857 0,02622277 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01311857 0,02620841 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01311857 0,02619406 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01311857 0,02617973 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01311857 0,02616542 ! ADP binding GO:0043531 15 13 0,000 0,01311857 0,02615112 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01311857 0,02613684 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01311857 0,02612257 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01311857 0,02610832 ! neuron fate specification GO:0048665 25 13 0,000 0,01311857 0,02609408 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01311857 0,02607986 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01311857 0,02606566 ! water transport GO:0006833 18 13 0,000 0,01311857 0,02605147 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01311857 0,0260373 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01311857 0,02602314 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01311857 0,02600899 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01311857 0,02599487 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01311857 0,02598075 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,01311857 0,02596666 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01311857 0,02595258 ! myoblast differentiation GO:0045445 15 13 0,000 0,01311857 0,02593851 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01311857 0,02592446 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01311857 0,02591042 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01311857 0,0258964 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01311857 0,0258824 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,01311857 0,0258684 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01311857 0,02585443 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01311857 0,02584047 ! exocrine system development GO:0035272 14 13 0,000 0,01311857 0,02582652 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01311857 0,02581259 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01311857 0,02579868 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01311857 0,02578478 ! L-glutamate transport GO:0015813 14 13 0,000 0,01311857 0,02577089 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01311857 0,02575702 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01311857 0,02574317 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01311857 0,02572933 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01311857 0,0257155 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01311857 0,02570169 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,01311857 0,0256879 ! genitalia development GO:0048806 18 13 0,000 0,01311857 0,02567411 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01311857 0,02566035 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01311857 0,0256466 ! MHC class I protein binding GO:0042288 23 13 0,000 0,01311857 0,02563286 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01311857 0,02561914 ! DNA methylation GO:0006306 15 13 0,000 0,01311857 0,02560543 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01311857 0,02559174 ! chromatin silencing GO:0006342 13 13 0,000 0,01311857 0,02557806 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01311857 0,0255644 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01311857 0,02555075 ! T cell homeostasis GO:0043029 14 13 0,000 0,01311857 0,02553711 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01311857 0,02552349 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01311857 0,02550989 ! response to gamma radiation GO:0010332 14 13 0,000 0,01311857 0,0254963 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01311857 0,02548272 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01311857 0,02546916 ! purine base metabolic process GO:0006144 15 13 0,000 0,01311857 0,02545561 ! cAMP binding GO:0030552 15 13 0,000 0,01311857 0,02544208 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01311857 0,02542856 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01311857 0,02541506 ! regulation of axon extension GO:0030516 16 13 0,000 0,01311857 0,02540157 ! drug transporter activity GO:0015238 14 13 0,000 0,01311857 0,02538809 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01311857 0,02537463 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01311857 0,02536118 ! response to cold GO:0009409 13 13 0,000 0,01311857 0,02534775 ! cadherin binding GO:0045296 16 13 0,000 0,01311857 0,02533433 ! nucleolar part GO:0044452 13 13 0,000 0,01311857 0,02532093 ! tRNA modification GO:0006400 14 14 0,000 0,01412091 0,02724118 ! cis-Golgi network GO:0005801 16 14 0,000 0,01412091 0,02722679 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,01412091 0,0272124 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,01412091 0,02719804 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,01412091 0,02718368 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,01412091 0,02716935 ! peroxisomal transport GO:0043574 14 14 0,000 0,01412091 0,02715502 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,01412091 0,02714072 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,01412091 0,02712642 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,01412091 0,02711215 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,01412091 0,02709789 ! negative regulation of peptidase activity GO:0010466 16 14 0,000 0,01412091 0,02708364 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,01412091 0,02706941 ! positive regulation of cell growth GO:0030307 15 14 0,000 0,01412091 0,02705519 ! caspase activator activity GO:0008656 16 14 0,000 0,01412091 0,02704099 ! MHC class II protein complex GO:0042613 19 14 0,000 0,01412091 0,0270268 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01412091 0,02701263 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,01412091 0,02699847 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,01412091 0,02698433 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,01412091 0,0269702 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01412091 0,02695609 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,01412091 0,02694199 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,01412091 0,0269279 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,01412091 0,02691383 ! response to vitamin A GO:0033189 18 14 0,000 0,01412091 0,02689978 ! actin filament bundle formation GO:0051017 16 14 0,000 0,01412091 0,02688574 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,01412091 0,02687172 ! plasma membrane fusion GO:0045026 15 14 0,000 0,01412091 0,02685771 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,01412091 0,02684371 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 14 14 0,000 0,01412091 0,02682973 ! presynaptic membrane GO:0042734 14 14 0,000 0,01412091 0,02681576 ! negative regulation of immune response GO:0050777 21 14 0,000 0,01412091 0,02680181 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,01412091 0,02678787 ! neural crest cell migration GO:0001755 15 14 0,000 0,01412091 0,02677395 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,01412091 0,02676004 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,01412091 0,02674615 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,01412091 0,02673227 ! cofactor transport GO:0051181 16 14 0,000 0,01412091 0,0267184 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01412091 0,02670455 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,01412091 0,02669072 ! cobalt ion binding GO:0050897 14 14 0,000 0,01412091 0,02667689 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01412091 0,02666308 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,01412091 0,02664929 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,01412091 0,02663551 ! gas transport GO:0015669 15 14 0,000 0,01412091 0,02662175 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,01412091 0,026608 ! heme biosynthetic process GO:0006783 14 14 0,000 0,01412091 0,02659426 ! release of cytochrome c from mitochondria GO:0001836 26 14 0,000 0,01412091 0,02658054 ! cerebellar cortex development GO:0021695 16 14 0,000 0,01412091 0,02656683 ! insulin secretion GO:0030073 17 14 0,000 0,01412091 0,02655313 ! tRNA binding GO:0000049 16 14 0,000 0,01412091 0,02653945 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,01412091 0,02652579 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,01412091 0,02651214 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,01412091 0,0264985 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,01412091 0,02648487 ! regulation of B cell proliferation GO:0030888 18 14 0,000 0,01412091 0,02647126 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,01412091 0,02645767 ! MAP kinase activity GO:0004707 16 14 0,000 0,01412091 0,02644409 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,01412091 0,02643052 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,01412091 0,02641696 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,01412091 0,02640342 ! C-C chemokine binding GO:0019957 15 14 0,000 0,01412091 0,0263899 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,01412091 0,02637639 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,01412091 0,02636289 ! response to osmotic stress GO:0006970 17 14 0,000 0,01412091 0,0263494 ! fructose metabolic process GO:0006000 15 14 0,000 0,01412091 0,02633593 ! telomeric DNA binding GO:0042162 17 14 0,000 0,01412091 0,02632247 ! monoamine transport GO:0015844 15 14 0,000 0,01412091 0,02630903 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,01412091 0,0262956 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01412091 0,02628218 ! dendritic spine GO:0043197 15 14 0,000 0,01412091 0,02626878 ! stem cell development GO:0048864 14 14 0,000 0,01412091 0,02625539 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,01412091 0,02624202 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,01412091 0,02622866 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,01412091 0,02621531 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,01412091 0,02620197 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01412091 0,02618865 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,01412091 0,02617535 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01412091 0,02616205 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,01412091 0,02614877 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,01412091 0,0261355 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,01412091 0,02612225 ! mannosidase activity GO:0015923 19 14 0,000 0,01412091 0,02610901 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,01412091 0,02609579 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,01412091 0,02608257 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,01412091 0,02606937 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,01412091 0,02605619 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,01412091 0,02604301 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01412091 0,02602985 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,01412091 0,02601671 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,01412091 0,02600357 ! sperm-egg recognition GO:0035036 17 14 0,000 0,01412091 0,02599045 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,01412091 0,02597735 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,01412091 0,02596425 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,01412091 0,02595117 ! positive regulation of translation GO:0045727 17 15 0,000 0,01512228 0,02777749 ! nuclear replication fork GO:0043596 26 15 0,000 0,01512228 0,02776351 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,01512228 0,02774954 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,01512228 0,02773559 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,01512228 0,02772165 ! endothelial cell migration GO:0043542 16 15 0,000 0,01512228 0,02770773 ! lipid phosphorylation GO:0046834 19 15 0,000 0,01512228 0,02769382 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01512228 0,02767993 ! response to vitamin GO:0033273 19 15 0,000 0,01512228 0,02766604 ! gene silencing by RNA GO:0031047 17 15 0,000 0,01512228 0,02765218 ! striated muscle thick filament GO:0005863 16 15 0,000 0,01512228 0,02763832 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,01512228 0,02762448 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,01512228 0,02761066 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,01512228 0,02759684 ! glutamate metabolic process GO:0006536 17 15 0,000 0,01512228 0,02758305 ! pituitary gland development GO:0021983 16 15 0,000 0,01512228 0,02756926 ! cholesterol binding GO:0015485 15 15 0,000 0,01512228 0,02755549 ! NAD metabolic process GO:0019674 17 15 0,000 0,01512228 0,02754173 ! protease binding GO:0002020 20 15 0,000 0,01512228 0,02752799 ! regulation of heart rate GO:0002027 20 15 0,000 0,01512228 0,02751426 ! actin filament bundle GO:0032432 18 15 0,000 0,01512228 0,02750054 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,01512228 0,02748684 ! regulation of exocytosis GO:0017157 16 15 0,000 0,01512228 0,02747315 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01512228 0,02745948 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,01512228 0,02744582 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,01512228 0,02743217 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,01512228 0,02741854 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,01512228 0,02740491 ! neuron recognition GO:0008038 18 15 0,000 0,01512228 0,02739131 ! regulation of Rho GTPase activity GO:0032319 18 15 0,000 0,01512228 0,02737771 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,01512228 0,02736413 ! filopodium GO:0030175 17 15 0,000 0,01512228 0,02735057 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,01512228 0,02733701 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,01512228 0,02732347 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,01512228 0,02730995 ! peptide hormone binding GO:0017046 16 15 0,000 0,01512228 0,02729643 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,01512228 0,02728293 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,01512228 0,02726945 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,01512228 0,02725597 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,01512228 0,02724251 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,01512228 0,02722907 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,01512228 0,02721564 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,01512228 0,02720222 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,01512228 0,02718881 ! developmental induction GO:0031128 17 15 0,000 0,01512228 0,02717542 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,01512228 0,02716203 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,01512228 0,02714867 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,01512228 0,02713531 ! lactation GO:0007595 17 15 0,000 0,01512228 0,02712197 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,01512228 0,02710864 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01512228 0,02709533 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01512228 0,02708203 ! double-strand break repair via homologous recombination GO:0000724 36 15 0,000 0,01512228 0,02706874 GO:0000725|recombinational repair, ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,01512228 0,02705546 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,01512228 0,0270422 ! sulfate transport GO:0008272 16 15 0,000 0,01512228 0,02702895 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,01512228 0,02701572 ! bile acid metabolic process GO:0008206 17 15 0,000 0,01512228 0,02700249 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,01512228 0,02698928 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,01512228 0,02697608 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,01512228 0,0269629 ! heart looping GO:0001947 18 15 0,000 0,01512228 0,02694973 ! protein kinase C activity GO:0004697 17 15 0,000 0,01512228 0,02693657 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,01512228 0,02692342 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,01512228 0,02691029 ! pigmentation during development GO:0048066 17 15 0,000 0,01512228 0,02689717 ! cytokine metabolic process GO:0042107 15 15 0,000 0,01512228 0,02688406 ! vesicle coating GO:0006901 17 15 0,000 0,01512228 0,02687097 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,01512228 0,02685788 ! neutral amino acid transport GO:0015804 18 15 0,000 0,01512228 0,02684481 ! L-amino acid transport GO:0015807 16 15 0,000 0,01512228 0,02683176 ! microfilament motor activity GO:0000146 15 15 0,000 0,01512228 0,02681871 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,01512228 0,02680568 ! regulation of vasodilation GO:0042312 25 15 0,000 0,01512228 0,02679266 ! DNA replication initiation GO:0006270 15 15 0,000 0,01512228 0,02677966 ! taste receptor activity GO:0008527 15 15 0,000 0,01512228 0,02676666 ! cellular pigmentation GO:0033059 16 15 0,000 0,01512228 0,02675368 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,01512228 0,02674071 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,01512228 0,02672776 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,01512228 0,02671481 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,01512228 0,02670188 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,01512228 0,02668897 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,01512228 0,02667606 ! ion gated channel activity GO:0022839 17 15 0,000 0,01512228 0,02666317 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,01512228 0,02665029 ! receptor activator activity GO:0030546 17 15 0,000 0,01512228 0,02663742 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,01512228 0,02662456 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,01512228 0,02661172 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,01512228 0,02659889 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,01512228 0,02658607 ! peptide hormone processing GO:0016486 19 15 0,000 0,01512228 0,02657326 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01512228 0,02656047 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,01612269 0,02830394 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01612269 0,02829033 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,01612269 0,02827673 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,01612269 0,02826314 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,01612269 0,02824956 ! kinesin complex GO:0005871 16 16 0,000 0,01612269 0,028236 ! photoreceptor cell development GO:0042461 22 16 0,000 0,01612269 0,02822245 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,01612269 0,02820892 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,01612269 0,02819539 ! centrosome cycle GO:0007098 26 16 0,000 0,01612269 0,02818188 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,01612269 0,02816839 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,01612269 0,0281549 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,01612269 0,02814143 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,01612269 0,02812797 ! lysosomal transport GO:0007041 16 16 0,000 0,01612269 0,02811453 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,01612269 0,02810109 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,01612269 0,02808767 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,01612269 0,02807427 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,01612269 0,02806087 ! myofibril assembly GO:0030239 17 16 0,000 0,01612269 0,02804749 GO:0055002|striated muscle cell development, ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 0,000 0,01612269 0,02803412 ! G1 phase GO:0051318 17 16 0,000 0,01612269 0,02802077 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,01612269 0,02800742 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,01612269 0,02799409 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,01612269 0,02798078 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,01612269 0,02796747 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,01612269 0,02795418 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,01612269 0,0279409 ! steroid catabolic process GO:0006706 18 16 0,000 0,01612269 0,02792763 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,01612269 0,02791438 ! cell-cell recognition GO:0009988 19 16 0,000 0,01612269 0,02790113 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,01612269 0,0278879 ! spleen development GO:0048536 19 16 0,000 0,01612269 0,02787469 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,01612269 0,02786148 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,01612269 0,02784829 ! neural tube closure GO:0001843 19 16 0,000 0,01612269 0,02783511 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,01612269 0,02782194 ! regulation of protein ubiquitination GO:0031396 27 16 0,000 0,01612269 0,02780879 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,01612269 0,02779565 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 0,000 0,01612269 0,02778252 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,01612269 0,0277694 ! viral genome replication GO:0019079 16 16 0,000 0,01612269 0,0277563 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,01612269 0,0277432 ! memory GO:0007613 18 16 0,000 0,01612269 0,02773012 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,01612269 0,02771705 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01612269 0,027704 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,01612269 0,02769096 ! glycoprotein binding GO:0001948 19 16 0,000 0,01612269 0,02767792 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,01612269 0,02766491 ! syntaxin binding GO:0019905 18 16 0,000 0,01612269 0,0276519 ! myosin binding GO:0017022 17 16 0,000 0,01612269 0,0276389 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,01612269 0,02762592 ! fucose metabolic process GO:0006004 18 16 0,000 0,01612269 0,02761295 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,01612269 0,0276 ! membrane budding GO:0006900 18 16 0,000 0,01612269 0,02758705 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,01612269 0,02757412 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,01612269 0,02756119 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,01612269 0,02754829 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,01612269 0,02753539 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,01612269 0,0275225 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,01612269 0,02750963 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,01612269 0,02749677 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,01612269 0,02748392 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,01612269 0,02747108 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,01612269 0,02745826 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01612269 0,02744545 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,01612269 0,02743264 ! axoneme GO:0005930 16 16 0,000 0,01612269 0,02741986 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,01612269 0,02740708 ! anion exchanger activity GO:0015380 17 17 0,000 0,01712214 0,02909249 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,01712214 0,02907895 ! skin development GO:0043588 20 17 0,000 0,01712214 0,02906541 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,01712214 0,0290519 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,01712214 0,02903839 ! glial cell development GO:0021782 17 17 0,000 0,01712214 0,0290249 ! limbic system development GO:0021761 18 17 0,000 0,01712214 0,02901141 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,01712214 0,02899795 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,01712214 0,02898449 ! ephrin receptor activity GO:0005003 21 17 0,000 0,01712214 0,02897105 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,01712214 0,02895761 ! glutamine metabolic process GO:0006541 26 17 0,000 0,01712214 0,0289442 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,01712214 0,02893079 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,01712214 0,0289174 ! signal sequence binding GO:0005048 18 17 0,000 0,01712214 0,02890401 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,01712214 0,02889065 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01712214 0,02887729 ! organelle subcompartment GO:0031984 19 17 0,000 0,01712214 0,02886394 ! regulation of dephosphorylation GO:0035303 20 17 0,000 0,01712214 0,02885061 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,01712214 0,02883729 ! membrane depolarization GO:0051899 19 17 0,000 0,01712214 0,02882398 ! oogenesis GO:0048477 20 17 0,000 0,01712214 0,02881069 ! nuclear outer membrane GO:0005640 21 17 0,000 0,01712214 0,02879741 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,01712214 0,02878414 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,01712214 0,02877088 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,01712214 0,02875763 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,01712214 0,0287444 ! organic cation transport GO:0015695 17 17 0,000 0,01712214 0,02873118 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,01712214 0,02871797 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,01712214 0,02870477 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,01712214 0,02869158 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,01712214 0,02867841 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,01712214 0,02866525 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,01712214 0,0286521 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,01712214 0,02863896 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,01712214 0,02862584 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01712214 0,02861272 ! lipid localization GO:0010876 19 17 0,000 0,01712214 0,02859962 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,01712214 0,02858653 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,01712214 0,02857346 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,01712214 0,02856039 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,01712214 0,02854734 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,01712214 0,0285343 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,01712214 0,02852127 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,01712214 0,02850825 ! response to hexose stimulus GO:0009746 20 17 0,000 0,01712214 0,02849524 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,01712214 0,02848225 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,01712214 0,02846927 ! AMP binding GO:0016208 19 17 0,000 0,01712214 0,0284563 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,01712214 0,02844334 ! receptor metabolic process GO:0043112 20 17 0,000 0,01712214 0,02843039 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,01712214 0,02841746 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,01712214 0,02840454 ! alcohol binding GO:0043178 20 17 0,000 0,01712214 0,02839162 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,01712214 0,02837873 ! visual learning GO:0008542 31 17 0,000 0,01712214 0,02836584 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,01712214 0,02835296 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,01712214 0,0283401 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,01712214 0,02832724 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,01712214 0,0283144 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,01712214 0,02830157 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,01712214 0,02828876 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,01712214 0,02827595 ! translation elongation factor activity GO:0003746 19 17 0,000 0,01712214 0,02826316 ! histone binding GO:0042393 26 17 0,000 0,01712214 0,02825037 ! cilium assembly GO:0042384 18 17 0,000 0,01712214 0,0282376 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,01712214 0,02822484 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,01712214 0,02821209 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,01712214 0,02819936 ! protein secretion GO:0009306 19 18 0,000 0,01812063 0,02983035 ! positive regulation of cell size GO:0045793 19 18 0,000 0,01812063 0,02981689 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01812063 0,02980345 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,01812063 0,02979002 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01812063 0,0297766 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid acetylation GO:0006473 21 18 0,000 0,01812063 0,02976319 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,01812063 0,0297498 ! cAMP metabolic process GO:0046058 18 18 0,000 0,01812063 0,02973642 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,01812063 0,02972304 ! cornified envelope GO:0001533 22 18 0,000 0,01812063 0,02970969 ! retinoid metabolic process GO:0001523 19 18 0,000 0,01812063 0,02969634 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,01812063 0,029683 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,01812063 0,02966968 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,01812063 0,02965637 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,01812063 0,02964307 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,01812063 0,02962979 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,01812063 0,02961651 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,01812063 0,02960325 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,01812063 0,02959 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,01812063 0,02957676 ! primary neural tube formation GO:0014020 21 18 0,000 0,01812063 0,02956353 ! recycling endosome GO:0055037 22 18 0,000 0,01812063 0,02955031 ! muscle cell development GO:0055001 20 18 0,000 0,01812063 0,02953711 ! kinase activator activity GO:0019209 22 18 0,000 0,01812063 0,02952392 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,01812063 0,02951074 ! cerebellum development GO:0021549 20 18 0,000 0,01812063 0,02949757 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,01812063 0,02948441 ! somitogenesis GO:0001756 20 18 0,000 0,01812063 0,02947127 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01812063 0,02945813 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,01812063 0,02944501 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,01812063 0,0294319 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,01812063 0,0294188 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,01812063 0,02940572 ! basal plasma membrane GO:0009925 21 18 0,000 0,01812063 0,02939264 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,01812063 0,02937958 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,01812063 0,02936653 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,01812063 0,02935349 ! negative regulation of translation GO:0017148 31 18 0,000 0,01812063 0,02934046 ! regulation of cell killing GO:0031341 24 18 0,000 0,01812063 0,02932744 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,01812063 0,02931443 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,01812063 0,02930144 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,01812063 0,02928846 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,01812063 0,02927549 ! protein complex scaffold GO:0032947 22 18 0,000 0,01812063 0,02926253 ! SNAP receptor activity GO:0005484 21 18 0,000 0,01812063 0,02924958 ! dendrite development GO:0016358 22 18 0,000 0,01812063 0,02923664 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,01812063 0,02922372 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,01812063 0,0292108 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,01812063 0,0291979 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,01812063 0,02918501 ! nuclear ubiquitin ligase complex GO:0000152 31 18 0,000 0,01812063 0,02917213 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,01812063 0,02915926 ! coreceptor activity GO:0015026 28 18 0,000 0,01812063 0,02914641 ! response to fungus GO:0009620 18 18 0,000 0,01812063 0,02913356 ! stem cell differentiation GO:0048863 18 18 0,000 0,01812063 0,02912073 ! intermediate filament-based process GO:0045103 18 18 0,000 0,01812063 0,0291079 ! heart process GO:0003015 19 18 0,000 0,01812063 0,02909509 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,01812063 0,02908229 ! vasodilation GO:0042311 20 18 0,000 0,01812063 0,0290695 ! transport vesicle membrane GO:0030658 23 18 0,000 0,01812063 0,02905673 ! MHC protein binding GO:0042287 30 18 0,000 0,01812063 0,02904396 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,01812063 0,0290312 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,01812063 0,02901846 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,01812063 0,02900573 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,01812063 0,028993 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,01812063 0,02898029 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,01812063 0,02896759 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,01812063 0,02895491 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,01812063 0,02894223 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,01911815 0,03052211 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,01911815 0,03050876 ! proteasome core complex GO:0005839 20 19 0,000 0,01911815 0,03049542 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,01911815 0,03048209 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,01911815 0,03046877 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,01911815 0,03045547 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,01911815 0,03044217 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,01911815 0,03042889 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,01911815 0,03041562 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,01911815 0,03040236 ! lysosome organization GO:0007040 20 19 0,000 0,01911815 0,03038912 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,01911815 0,03037588 ! central nervous system neuron development GO:0021954 21 19 0,000 0,01911815 0,03036266 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,01911815 0,03034944 GO:0070003|threonine-type peptidase activity, ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,01911815 0,03033624 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,01911815 0,03032305 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,01911815 0,03030987 ! peptide cross-linking GO:0018149 23 19 0,000 0,01911815 0,03029671 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,01911815 0,03028355 ! beta-catenin binding GO:0008013 23 19 0,000 0,01911815 0,03027041 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,01911815 0,03025728 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,01911815 0,03024415 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01911815 0,03023105 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,01911815 0,03021795 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,01911815 0,03020486 ! vitamin transport GO:0051180 21 19 0,000 0,01911815 0,03019178 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,01911815 0,03017872 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,01911815 0,03016567 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,01911815 0,03015262 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,01911815 0,03013959 ! retinoid binding GO:0005501 19 19 0,000 0,01911815 0,03012657 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,01911815 0,03011357 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,01911815 0,03010057 ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,01911815 0,03008758 ! positive regulation of fibroblast proliferation GO:0048146 25 19 0,000 0,01911815 0,03007461 ! gluconeogenesis GO:0006094 23 19 0,000 0,01911815 0,03006165 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,01911815 0,03004869 ! microtubule-based transport GO:0010970 20 19 0,000 0,01911815 0,03003575 ! superoxide metabolic process GO:0006801 21 19 0,000 0,01911815 0,03002282 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,01911815 0,03000991 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01911815 0,029997 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,01911815 0,0299841 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,01911815 0,02997122 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,01911815 0,02995834 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,01911815 0,02994548 ! acetylcholine binding GO:0042166 20 19 0,000 0,01911815 0,02993263 ! heme metabolic process GO:0042168 20 19 0,000 0,01911815 0,02991979 ! SH2 domain binding GO:0042169 25 19 0,000 0,01911815 0,02990696 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,01911815 0,02989414 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,01911815 0,02988133 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,01911815 0,02986853 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,01911815 0,02985575 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,01911815 0,02984297 ! body fluid secretion GO:0007589 21 19 0,000 0,01911815 0,02983021 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,01911815 0,02981745 ! secretory granule membrane GO:0030667 21 19 0,000 0,01911815 0,02980471 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,01911815 0,02979198 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,01911815 0,02977926 ! peptidase activator activity GO:0016504 21 19 0,000 0,01911815 0,02976655 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01911815 0,02975385 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,01911815 0,02974116 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,01911815 0,02972848 ! sialyltransferase activity GO:0008373 31 19 0,000 0,01911815 0,02971582 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,01911815 0,02970316 ! chaperone binding GO:0051087 21 20 0,000 0,02011472 0,03123818 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,02011472 0,03122489 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,02011472 0,03121161 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,02011472 0,03119834 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,02011472 0,03118508 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,02011472 0,03117183 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,02011472 0,03115859 ! negative regulation of lipid metabolic process GO:0045833 34 20 0,000 0,02011472 0,03114537 ! ovarian follicle development GO:0001541 21 20 0,000 0,02011472 0,03113215 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 0,000 0,02011472 0,03111895 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,02011472 0,03110576 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,02011472 0,03109258 ! diencephalon development GO:0021536 22 20 0,000 0,02011472 0,03107941 ! nuclear inner membrane GO:0005637 21 20 0,000 0,02011472 0,03106625 ! regulation of lipid transport GO:0032368 22 20 0,000 0,02011472 0,03105311 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,02011472 0,03103997 ! glutathione metabolic process GO:0006749 21 20 0,000 0,02011472 0,03102685 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,02011472 0,03101373 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,02011472 0,03100063 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,02011472 0,03098754 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,02011472 0,03097446 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,02011472 0,03096139 ! peptide hormone secretion GO:0030072 25 20 0,000 0,02011472 0,03094833 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,02011472 0,03093528 ! Rab GTPase binding GO:0017137 22 20 0,000 0,02011472 0,03092225 ! initiation of viral infection GO:0019059 22 20 0,000 0,02011472 0,03090922 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,02011472 0,03089621 ! heterochromatin GO:0000792 20 20 0,000 0,02011472 0,0308832 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,02011472 0,03087021 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,02011472 0,03085723 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,02011472 0,03084426 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,02011472 0,0308313 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,02011472 0,03081835 ! visual behavior GO:0007632 34 20 0,000 0,02011472 0,03080541 ! regulation of cell-matrix adhesion GO:0001952 26 20 0,000 0,02011472 0,03079248 GO:0010810|regulation of cell-substrate adhesion, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,02011472 0,03077957 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,02011472 0,03076666 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,02011472 0,03075377 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,02011472 0,03074088 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,02011472 0,03072801 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,02011472 0,03071515 ! rRNA binding GO:0019843 22 20 0,000 0,02011472 0,0307023 ! cytolysis GO:0019835 22 20 0,000 0,02011472 0,03068946 ! renal system process GO:0003014 22 20 0,000 0,02011472 0,03067663 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,02011472 0,03066381 ! fatty acid transport GO:0015908 23 20 0,000 0,02011472 0,030651 ! transaminase activity GO:0008483 22 20 0,000 0,02011472 0,0306382 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,02011472 0,03062541 ! collagen catabolic process GO:0030574 21 20 0,000 0,02011472 0,03061264 ! microvillus GO:0005902 25 20 0,000 0,02011472 0,03059987 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,02011472 0,03058711 ! connexon complex GO:0005922 23 20 0,000 0,02011472 0,03057437 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,02111032 0,03207433 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,02111032 0,03206097 ! translational initiation GO:0006413 21 21 0,000 0,02111032 0,03204763 ! NF-kappaB binding GO:0051059 31 21 0,000 0,02111032 0,0320343 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,02111032 0,03202098 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,02111032 0,03200767 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,02111032 0,03199437 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,02111032 0,03198109 ! glutathione transferase activity GO:0004364 21 21 0,000 0,02111032 0,03196781 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,02111032 0,03195455 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,02111032 0,03194129 ! regeneration GO:0031099 24 21 0,000 0,02111032 0,03192805 ! apoptotic mitochondrial changes GO:0008637 33 21 0,000 0,02111032 0,03191482 ! MHC class I protein complex GO:0042612 31 21 0,000 0,02111032 0,0319016 ! cellular response to starvation GO:0009267 22 21 0,000 0,02111032 0,03188839 ! peroxisome organization GO:0007031 22 21 0,000 0,02111032 0,03187519 ! vacuole organization GO:0007033 23 21 0,000 0,02111032 0,031862 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,02111032 0,03184882 ! neural crest cell development GO:0014032 24 21 0,000 0,02111032 0,03183566 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,02111032 0,0318225 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,02111032 0,03180936 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,02111032 0,03179623 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02111032 0,0317831 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,02111032 0,03176999 ! pallium development GO:0021543 22 21 0,000 0,02111032 0,03175689 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,02111032 0,0317438 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,02111032 0,03173072 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,02111032 0,03171765 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,02111032 0,03170459 ! cyclase activity GO:0009975 22 21 0,000 0,02111032 0,03169155 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,02111032 0,03167851 ! gut development GO:0048565 23 21 0,000 0,02111032 0,03166548 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,02111032 0,03165247 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,02111032 0,03163946 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02111032 0,03162647 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,02111032 0,03161349 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02111032 0,03160052 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,02111032 0,03158755 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,02111032 0,0315746 ! axis specification GO:0009798 25 21 0,000 0,02111032 0,03156166 ! response to alkaloid GO:0043279 27 21 0,000 0,02111032 0,03154873 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,02111032 0,03153581 ! response to ethanol GO:0045471 28 21 0,000 0,02111032 0,03152291 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,02111032 0,03151001 ! smooth muscle contraction GO:0006939 25 21 0,000 0,02111032 0,03149712 ! vesicle targeting GO:0006903 22 21 0,000 0,02111032 0,03148424 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,02111032 0,03147138 ! SNARE binding GO:0000149 24 21 0,000 0,02111032 0,03145852 ! interaction with host GO:0051701 26 21 0,000 0,02111032 0,03144567 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,02111032 0,03143284 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,02111032 0,03142002 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,02111032 0,0314072 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,02111032 0,0313944 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,02111032 0,0313816 ! cell-cell junction organization GO:0045216 24 21 0,000 0,02111032 0,03136882 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,02111032 0,03135605 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,02111032 0,03134329 ! caveola GO:0005901 25 21 0,000 0,02111032 0,03133054 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,02111032 0,03131779 ! insulin receptor binding GO:0005158 25 21 0,000 0,02111032 0,03130506 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02111032 0,03129234 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02111032 0,03127963 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,02210497 0,03274013 ! metencephalon development GO:0022037 25 22 0,000 0,02210497 0,03272684 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,02210497 0,03271356 ! hormone secretion GO:0046879 28 22 0,000 0,02210497 0,0327003 ! vesicle docking GO:0048278 24 22 0,000 0,02210497 0,03268704 ! muscle myosin complex GO:0005859 23 22 0,000 0,02210497 0,0326738 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,02210497 0,03266056 ! actomyosin structure organization GO:0031032 24 22 0,000 0,02210497 0,03264734 ! microtubule organizing center organization GO:0031023 33 22 0,000 0,02210497 0,03263413 GO:0051297|centrosome organization, ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,02210497 0,03262093 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 0,000 0,02210497 0,03260774 ! sperm motility GO:0030317 23 22 0,000 0,02210497 0,03259456 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,02210497 0,03258139 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,02210497 0,03256823 ! vacuolar transport GO:0007034 22 22 0,000 0,02210497 0,03255508 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,02210497 0,03254194 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,02210497 0,03252881 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,02210497 0,0325157 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,02210497 0,03250259 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,02210497 0,0324895 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,02210497 0,03247641 ! PML body GO:0016605 25 22 0,000 0,02210497 0,03246334 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,02210497 0,03245027 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,02210497 0,03243722 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,02210497 0,03242418 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,02210497 0,03241115 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,02210497 0,03239812 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,02210497 0,03238511 ! pentose metabolic process GO:0019321 23 22 0,000 0,02210497 0,03237211 ! collagen fibril organization GO:0030199 32 22 0,000 0,02210497 0,03235912 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,02210497 0,03234614 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,02210497 0,03233317 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,02210497 0,03232021 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,02210497 0,03230726 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! positive regulation of B cell activation GO:0050871 26 22 0,000 0,02210497 0,03229432 ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,02210497 0,0322814 ! positive regulation of behavior GO:0048520 24 22 0,000 0,02210497 0,03226848 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,02210497 0,03225557 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,02210497 0,03224267 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,02210497 0,03222979 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,02210497 0,03221691 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,02210497 0,03220405 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,02210497 0,03219119 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,02210497 0,03217834 ! glycerol metabolic process GO:0006071 24 22 0,000 0,02210497 0,03216551 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,02210497 0,03215268 ! nuclear chromatin GO:0000790 23 22 0,000 0,02210497 0,03213987 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,02210497 0,03212706 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,02210497 0,03211427 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,02210497 0,03210148 ! sterol binding GO:0032934 24 22 0,000 0,02210497 0,03208871 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,02210497 0,03207595 ! digestive system process GO:0022600 25 22 0,000 0,02210497 0,03206319 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,02210497 0,03205045 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,02210497 0,03203772 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,02210497 0,03202499 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,02210497 0,03201228 ! base-excision repair GO:0006284 33 22 0,000 0,02210497 0,03199958 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,02210497 0,03198688 ! DNA modification GO:0006304 25 22 0,000 0,02210497 0,0319742 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,02210497 0,03196153 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,02210497 0,03194886 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,02210497 0,03193621 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,02210497 0,03192357 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,02210497 0,03191093 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,02210497 0,03189831 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,02210497 0,0318857 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,02210497 0,03187309 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,02309866 0,03329273 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,02309866 0,03327958 ! leukocyte adhesion GO:0007159 26 23 0,000 0,02309866 0,03326645 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,02309866 0,03325332 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,02309866 0,0332402 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,02309866 0,03322709 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,02309866 0,033214 ! ureteric bud development GO:0001657 24 23 0,000 0,02309866 0,03320091 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,02309866 0,03318783 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,02309866 0,03317477 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,02309866 0,03316171 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,02309866 0,03314867 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,02309866 0,03313563 ! deaminase activity GO:0019239 24 23 0,000 0,02309866 0,03312261 ! sensory perception of pain GO:0019233 26 23 0,000 0,02309866 0,03310959 ! lipid kinase activity GO:0001727 26 23 0,000 0,02309866 0,03309659 ! platelet activation GO:0030168 27 23 0,000 0,02309866 0,03308359 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,02309866 0,03307061 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,02309866 0,03305763 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,02309866 0,03304467 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,02309866 0,03303172 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,02309866 0,03301877 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,02309866 0,03300584 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,02309866 0,03299292 ! cell surface binding GO:0043498 28 23 0,000 0,02309866 0,03298 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,02309866 0,0329671 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,02309866 0,03295421 ! regulation of glucose import GO:0046324 28 23 0,000 0,02309866 0,03294132 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,02309866 0,03292845 ! alditol metabolic process GO:0019400 25 23 0,000 0,02309866 0,03291559 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,02309866 0,03290274 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,02309866 0,03288989 ! zinc ion transport GO:0006829 26 23 0,000 0,02309866 0,03287706 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,02309866 0,03286424 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,02309866 0,03285143 ! sex determination GO:0007530 25 23 0,000 0,02309866 0,03283862 ! phosphate binding GO:0042301 25 23 0,000 0,02309866 0,03282583 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,02309866 0,03281305 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,02309866 0,03280028 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,02309866 0,03278751 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,02309866 0,03277476 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,02309866 0,03276202 ! positive regulation of nuclear division GO:0051785 35 23 0,000 0,02309866 0,03274928 GO:0045840|positive regulation of mitosis, ! synaptogenesis GO:0007416 25 23 0,000 0,02309866 0,03273656 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,02309866 0,03272385 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,02309866 0,03271114 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,02309866 0,03269845 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,02309866 0,03268577 ! leukocyte proliferation GO:0070661 26 23 0,000 0,02309866 0,03267309 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,02309866 0,03266043 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,02409139 0,03405091 ! actin filament GO:0005884 26 24 0,000 0,02409139 0,03403772 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02409139 0,03402454 ! pancreas development GO:0031016 27 24 0,000 0,02409139 0,03401138 ! androgen receptor binding GO:0050681 34 24 0,000 0,02409139 0,03399822 ! calcium channel complex GO:0034704 31 24 0,000 0,02409139 0,03398507 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,02409139 0,03397194 ! negative regulation of cell development GO:0010721 30 24 0,000 0,02409139 0,03395881 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,02409139 0,03394569 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,02409139 0,03393259 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,02409139 0,03391949 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,02409139 0,0339064 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,02409139 0,03389333 ! Rho GTPase binding GO:0017048 36 24 0,000 0,02409139 0,03388026 ! regulation of glucose transport GO:0010827 29 24 0,000 0,02409139 0,03386721 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,02409139 0,03385416 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,02409139 0,03384112 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,02409139 0,0338281 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,02409139 0,03381508 ! protein stabilization GO:0050821 24 24 0,000 0,02409139 0,03380208 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,02409139 0,03378908 ! embryonic pattern specification GO:0009880 29 24 0,000 0,02409139 0,03377609 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,02409139 0,03376312 ! RNA polymerase complex GO:0030880 25 24 0,000 0,02409139 0,03375015 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,02409139 0,0337372 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,02409139 0,03372425 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,02409139 0,03371131 ! chemokine binding GO:0019956 26 24 0,000 0,02409139 0,03369839 ! catechol metabolic process GO:0009712 29 24 0,000 0,02409139 0,03368547 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,02409139 0,03367257 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,02409139 0,03365967 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,02409139 0,03364678 ! cell aging GO:0007569 47 24 0,000 0,02409139 0,03363391 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,02409139 0,03362104 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,02409139 0,03360818 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,02409139 0,03359534 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,02409139 0,0335825 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,02409139 0,03356967 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,02409139 0,03355685 ! caspase regulator activity GO:0043028 26 24 0,000 0,02409139 0,03354404 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 0,000 0,02409139 0,03353125 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,02409139 0,03351846 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,02409139 0,03350568 ! selenium binding GO:0008430 24 24 0,000 0,02409139 0,03349291 ! spindle pole GO:0000922 35 24 0,000 0,02409139 0,03348015 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,02409139 0,0334674 ! phenol metabolic process GO:0018958 31 25 0,000 0,02508317 0,0348319 ! regulation of lipid biosynthetic process GO:0046890 35 25 0,000 0,02508317 0,03481865 ! protein amino acid acylation GO:0043543 28 25 0,000 0,02508317 0,0348054 ! aromatase activity GO:0070330 28 25 0,000 0,02508317 0,03479217 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,02508317 0,03477894 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,02508317 0,03476573 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,02508317 0,03475253 ! response to starvation GO:0042594 26 25 0,000 0,02508317 0,03473933 ! dynein complex GO:0030286 28 25 0,000 0,02508317 0,03472615 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,02508317 0,03471297 ! regulation of behavior GO:0050795 27 25 0,000 0,02508317 0,03469981 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,02508317 0,03468666 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,02508317 0,03467351 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,02508317 0,03466038 ! hormone transport GO:0009914 31 25 0,000 0,02508317 0,03464726 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,02508317 0,03463414 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,02508317 0,03462104 ! regulation of coagulation GO:0050818 28 25 0,000 0,02508317 0,03460794 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,02508317 0,03459486 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,02508317 0,03458178 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,02508317 0,03456872 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,02508317 0,03455566 ! molting cycle process GO:0022404 28 25 0,000 0,02508317 0,03454262 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,02508317 0,03452959 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,02508317 0,03451656 ! phototransduction GO:0007602 27 25 0,000 0,02508317 0,03450354 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,02508317 0,03449054 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,02508317 0,03447754 ! protein phosphatase binding GO:0019903 27 25 0,000 0,02508317 0,03446456 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,02508317 0,03445158 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,02508317 0,03443862 ! autophagy GO:0006914 28 25 0,000 0,02508317 0,03442566 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,02508317 0,03441271 ! response to ionizing radiation GO:0010212 37 25 0,000 0,02508317 0,03439977 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,02508317 0,03438685 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,02607399 0,03573175 ! positive regulation of cell adhesion GO:0045785 34 26 0,000 0,02607399 0,03571833 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,02607399 0,03570492 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,02607399 0,03569153 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,02607399 0,03567814 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,02607399 0,03566476 ! hair cycle GO:0042633 29 26 0,000 0,02607399 0,03565139 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,02607399 0,03563804 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,02607399 0,03562469 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,02607399 0,03561135 ! early endosome membrane GO:0031901 31 26 0,000 0,02607399 0,03559802 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,02607399 0,03558471 ! iron ion homeostasis GO:0055072 29 26 0,000 0,02607399 0,0355714 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,02607399 0,0355581 ! GABA receptor activity GO:0016917 31 26 0,000 0,02607399 0,03554481 ! PDZ domain binding GO:0030165 28 26 0,000 0,02607399 0,03553154 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,02607399 0,03551827 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,02607399 0,03550501 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,02607399 0,03549176 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,02607399 0,03547852 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,02607399 0,03546529 ! fatty acid binding GO:0005504 28 26 0,000 0,02607399 0,03545208 ! blastocyst development GO:0001824 27 26 0,000 0,02607399 0,03543887 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,02607399 0,03542567 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,02607399 0,03541248 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,02607399 0,0353993 ! regulation of fibroblast proliferation GO:0048145 32 26 0,000 0,02607399 0,03538613 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,02607399 0,03537297 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,02607399 0,03535982 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02607399 0,03534668 ! iron ion transport GO:0006826 33 26 0,000 0,02607399 0,03533355 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,02607399 0,03532043 ! glucose transport GO:0015758 27 26 0,000 0,02607399 0,03530732 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,02607399 0,03529422 ! spinal cord development GO:0021510 30 26 0,000 0,02607399 0,03528113 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,02607399 0,03526805 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,02607399 0,03525497 ! RNA helicase activity GO:0003724 46 26 0,000 0,02607399 0,03524191 ! brush border GO:0005903 30 26 0,000 0,02607399 0,03522886 ! gap junction GO:0005921 29 26 0,000 0,02607399 0,03521582 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,02607399 0,03520278 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,02706386 0,0365257 ! RNA export from nucleus GO:0006405 31 27 0,000 0,02706386 0,03651219 ! mRNA catabolic process GO:0006402 31 27 0,000 0,02706386 0,03649869 ! myelination GO:0042552 31 27 0,000 0,02706386 0,0364852 ! trans-Golgi network GO:0005802 31 27 0,000 0,02706386 0,03647172 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,02706386 0,03645826 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,02706386 0,0364448 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,02706386 0,03643135 ! vasculogenesis GO:0001570 32 27 0,000 0,02706386 0,03641791 ! hexose transport GO:0008645 28 27 0,000 0,02706386 0,03640448 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,02706386 0,03639106 ! spindle organization GO:0007051 38 27 0,000 0,02706386 0,03637766 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,02706386 0,03636426 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,02706386 0,03635087 ! cell fate determination GO:0001709 29 27 0,000 0,02706386 0,03633749 ! lipid oxidation GO:0034440 29 27 0,000 0,02706386 0,03632412 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,02706386 0,03631076 ! collagen binding GO:0005518 29 27 0,000 0,02706386 0,03629741 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,02706386 0,03628407 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,02706386 0,03627074 ! liver development GO:0001889 33 27 0,000 0,02706386 0,03625742 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,02706386 0,03624411 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,02706386 0,03623081 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,02706386 0,03621752 ! membrane docking GO:0022406 29 27 0,000 0,02706386 0,03620424 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,02706386 0,03619097 GO:0050908|detection of light stimulus involved in visual perception, ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,02706386 0,03617771 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,02706386 0,03616445 ! phospholipid transport GO:0015914 29 27 0,000 0,02706386 0,03615121 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,02706386 0,03613798 ! aminopeptidase activity GO:0004177 33 27 0,000 0,02706386 0,03612476 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,02706386 0,03611154 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,02706386 0,03609834 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,02706386 0,03608515 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,02706386 0,03607196 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,02706386 0,03605879 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,02805277 0,03736273 ! Golgi stack GO:0005795 30 28 0,000 0,02805277 0,03734909 ! male gonad development GO:0008584 32 28 0,000 0,02805277 0,03733547 ! regulation of fatty acid metabolic process GO:0019217 41 28 0,000 0,02805277 0,03732185 ! lipoprotein binding GO:0008034 31 28 0,000 0,02805277 0,03730825 ! mesoderm formation GO:0001707 34 28 0,000 0,02805277 0,03729465 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,02805277 0,03728106 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,02805277 0,03726749 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,02805277 0,03725392 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,02805277 0,03724036 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,02805277 0,03722682 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,02805277 0,03721328 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,02805277 0,03719975 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,02805277 0,03718624 ! tissue homeostasis GO:0001894 31 28 0,000 0,02805277 0,03717273 GO:0048871|multicellular organismal homeostasis, ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,02805277 0,03715923 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,02805277 0,03714574 ! sister chromatid segregation GO:0000819 49 28 0,000 0,02805277 0,03713226 ! post-embryonic development GO:0009791 32 28 0,000 0,02805277 0,0371188 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,02805277 0,03710534 ! negative regulation of phosphorylation GO:0042326 30 28 0,000 0,02805277 0,03709189 ! detection of visible light GO:0009584 30 28 0,000 0,02805277 0,03707845 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,02805277 0,03706502 ! receptor regulator activity GO:0030545 31 28 0,000 0,02805277 0,0370516 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,02805277 0,03703819 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,02805277 0,03702479 ! response to heat GO:0009408 33 28 0,000 0,02805277 0,0370114 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,02805277 0,03699802 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,02904074 0,03828717 ! hormone binding GO:0042562 31 29 0,000 0,02904074 0,03827334 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,02904074 0,03825952 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,02904074 0,03824571 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,02904074 0,0382319 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,02904074 0,03821811 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,02904074 0,03820433 ! erythrocyte differentiation GO:0030218 35 29 0,000 0,02904074 0,03819056 ! ceramide metabolic process GO:0006672 29 29 0,000 0,02904074 0,0381768 ! replication fork GO:0005657 42 29 0,000 0,02904074 0,03816304 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,02904074 0,0381493 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,02904074 0,03813557 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,02904074 0,03812185 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,02904074 0,03810813 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,02904074 0,03809443 ! regulation of pH GO:0006885 30 29 0,000 0,02904074 0,03808074 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,02904074 0,03806705 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,02904074 0,03805338 ! phospholipase C activity GO:0004629 43 29 0,000 0,02904074 0,03803972 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,02904074 0,03802606 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,02904074 0,03801242 ! sodium channel activity GO:0005272 33 29 0,000 0,02904074 0,03799878 ! sarcoplasm GO:0016528 31 29 0,000 0,02904074 0,03798516 ! detection of light stimulus GO:0009583 31 29 0,000 0,02904074 0,03797154 ! spermatid development GO:0007286 30 29 0,000 0,02904074 0,03795794 ! DNA polymerase activity GO:0034061 34 29 0,000 0,02904074 0,03794434 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,02904074 0,03793076 ! sarcolemma GO:0042383 30 29 0,000 0,02904074 0,03791718 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,02904074 0,03790362 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,02904074 0,03789006 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,02904074 0,03787651 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,03002775 0,03914983 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,03002775 0,03913584 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,03002775 0,03912187 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,03002775 0,0391079 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,03002775 0,03909394 ! scavenger receptor activity GO:0005044 39 30 0,000 0,03002775 0,03907999 ! spliceosome assembly GO:0000245 34 30 0,000 0,03002775 0,03906606 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,03002775 0,03905213 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,03002775 0,03903821 ! metanephros development GO:0001656 31 30 0,000 0,03002775 0,03902431 ! glutamate receptor activity GO:0008066 35 30 0,000 0,03002775 0,03901041 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,03002775 0,03899652 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,03002775 0,03898264 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,03002775 0,03896877 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,03002775 0,03895492 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,03002775 0,03894107 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,03002775 0,03892723 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,03002775 0,0389134 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,03002775 0,03889958 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,03002775 0,03888577 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,03002775 0,03887197 ! protein-lipid complex GO:0032994 41 30 0,000 0,03002775 0,03885819 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,03002775 0,03884441 ! negative regulation of protein modification process GO:0031400 34 30 0,000 0,03002775 0,03883064 ! phosphatase binding GO:0019902 34 30 0,000 0,03002775 0,03881688 ! acute-phase response GO:0006953 44 30 0,000 0,03002775 0,03880313 ! segmentation GO:0035282 37 30 0,000 0,03002775 0,03878939 ! response to toxin GO:0009636 33 30 0,000 0,03002775 0,03877565 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,03002775 0,03876193 ! antigen binding GO:0003823 33 30 0,000 0,03002775 0,03874822 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,03002775 0,03873452 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,03002775 0,03872083 ! ensheathment of neurons GO:0007272 35 30 0,000 0,03002775 0,03870715 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,03002775 0,03869347 ! regulation of microtubule-based process GO:0032886 41 30 0,000 0,03002775 0,03867981 ! vesicle localization GO:0051648 31 30 0,000 0,03002775 0,03866616 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,03101381 0,0399218 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03101381 0,03990772 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 0,000 0,03101381 0,03989364 GO:0045936|negative regulation of phosphate metabolic process, ! acrosomal vesicle GO:0001669 34 31 0,000 0,03101381 0,03987958 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03101381 0,03986553 ! protein targeting to membrane GO:0006612 35 31 0,000 0,03101381 0,03985149 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,03101381 0,03983746 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,03101381 0,03982343 ! formation of primary germ layer GO:0001704 37 31 0,000 0,03101381 0,03980942 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,03101381 0,03979542 ! endocytic vesicle GO:0030139 33 31 0,000 0,03101381 0,03978143 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,03101381 0,03976744 ! spermatid differentiation GO:0048515 32 31 0,000 0,03101381 0,03975347 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,03101381 0,03973951 ! neuron fate commitment GO:0048663 44 31 0,000 0,03101381 0,03972555 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,03101381 0,03971161 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,03101381 0,03969767 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,03101381 0,03968375 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,03101381 0,03966984 ! cell junction assembly GO:0034329 36 31 0,000 0,03101381 0,03965593 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,03101381 0,03964204 ! peptide transport GO:0015833 36 31 0,000 0,03101381 0,03962815 ! peripheral nervous system development GO:0007422 35 31 0,000 0,03101381 0,03961428 ! I band GO:0031674 34 31 0,000 0,03101381 0,03960041 ! BMP signaling pathway GO:0030509 33 31 0,000 0,03101381 0,03958655 ! adult locomotory behavior GO:0008344 37 31 0,000 0,03101381 0,03957271 ! gene silencing GO:0016458 33 31 0,000 0,03101381 0,03955887 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,03199892 0,04080114 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,03199892 0,04078688 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,03199892 0,04077264 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,03199892 0,0407584 ! meiosis I GO:0007127 53 32 0,000 0,03199892 0,04074417 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,03199892 0,04072996 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,03199892 0,04071575 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,03199892 0,04070155 ! vesicle coat GO:0030120 39 32 0,000 0,03199892 0,04068737 ! cytokine production GO:0001816 32 32 0,000 0,03199892 0,04067319 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,03199892 0,04065902 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,03199892 0,04064487 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,03199892 0,04063072 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,03199892 0,04061658 ! oxygen binding GO:0019825 33 32 0,000 0,03199892 0,04060246 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,03199892 0,04058834 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,03199892 0,04057423 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,03199892 0,04056013 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,03199892 0,04054604 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,03298308 0,04177857 ! DNA helicase activity GO:0003678 55 33 0,000 0,03298308 0,04176407 ! neural tube development GO:0021915 37 33 0,000 0,03298308 0,04174958 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,03298308 0,0417351 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,03298308 0,04172062 ! organelle envelope lumen GO:0031970 46 33 0,000 0,03298308 0,04170616 ! regulation of cellular ketone metabolic process GO:0010565 46 33 0,000 0,03298308 0,04169171 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,03298308 0,04167727 ! NAD or NADH binding GO:0051287 36 33 0,000 0,03298308 0,04166284 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,03298308 0,04164842 ! B cell differentiation GO:0030183 37 33 0,000 0,03298308 0,04163401 ! aerobic respiration GO:0009060 35 33 0,000 0,03298308 0,04161961 ! embryonic organ development GO:0048568 41 33 0,000 0,03298308 0,04160521 ! placenta development GO:0001890 39 33 0,000 0,03298308 0,04159083 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,03298308 0,04157646 ! tissue remodeling GO:0048771 37 33 0,000 0,03298308 0,0415621 ! flagellum GO:0019861 34 33 0,000 0,03298308 0,04154775 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,03298308 0,04153341 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03298308 0,04151908 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,03298308 0,04150475 ! odontogenesis GO:0042476 39 34 0,000 0,0339663 0,04272726 ! lipid homeostasis GO:0055088 37 34 0,000 0,0339663 0,04271253 ! telencephalon development GO:0021537 36 34 0,000 0,0339663 0,04269781 ! negative regulation of hydrolase activity GO:0051346 36 34 0,000 0,0339663 0,0426831 ! clathrin coat GO:0030118 41 34 0,000 0,0339663 0,0426684 ! cell growth GO:0016049 36 34 0,000 0,0339663 0,04265372 ! regulation of B cell activation GO:0050864 40 34 0,000 0,0339663 0,04263904 ! protein polymerization GO:0051258 38 34 0,000 0,0339663 0,04262437 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,0339663 0,04260971 ! learning GO:0007612 51 34 0,000 0,0339663 0,04259507 ! keratinization GO:0031424 40 34 0,000 0,0339663 0,04258043 ! ovulation cycle process GO:0022602 35 34 0,000 0,0339663 0,0425658 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,0339663 0,04255118 ! steroid hormone receptor binding GO:0035258 44 34 0,000 0,0339663 0,04253658 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,0339663 0,04252198 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,0339663 0,04250739 ! amino acid binding GO:0016597 40 34 0,000 0,0339663 0,04249281 ! regulation of protein stability GO:0031647 35 34 0,000 0,0339663 0,04247825 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,0339663 0,04246369 ! glycogen metabolic process GO:0005977 48 34 0,000 0,0339663 0,04244914 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,0339663 0,0424346 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,0339663 0,04242008 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,0339663 0,04240556 ! protein kinase inhibitor activity GO:0004860 37 34 0,000 0,0339663 0,04239105 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,03494856 0,04360204 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 53 35 0,000 0,03494856 0,04358713 ! response to estrogen stimulus GO:0043627 48 35 0,000 0,03494856 0,04357223 ! inner ear morphogenesis GO:0042472 46 35 0,000 0,03494856 0,04355735 ! MHC protein complex GO:0042611 50 35 0,000 0,03494856 0,04354247 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,03494856 0,04352761 ! vesicle lumen GO:0031983 38 35 0,000 0,03494856 0,04351275 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,03494856 0,0434979 ! mesenchymal cell development GO:0014031 40 35 0,000 0,03494856 0,04348307 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,03494856 0,04346824 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,03494856 0,04345343 ! kinase inhibitor activity GO:0019210 47 35 0,000 0,03494856 0,04343862 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,03494856 0,04342383 ! regulation of proteolysis GO:0030162 37 35 0,000 0,03494856 0,04340904 ! ovulation cycle GO:0042698 37 35 0,000 0,03494856 0,04339427 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,03494856 0,0433795 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,03494856 0,04336475 ! collagen GO:0005581 54 35 0,000 0,03494856 0,04335 ! glucan metabolic process GO:0044042 49 35 0,000 0,03494856 0,04333527 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,03494856 0,04332054 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,03494856 0,04330583 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,03494856 0,04329112 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,03494856 0,04327643 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,03494856 0,04326174 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,03494856 0,04324707 ! maintenance of protein location GO:0045185 45 35 0,000 0,03494856 0,0432324 ! polyol metabolic process GO:0019751 46 35 0,000 0,03494856 0,04321775 ! androgen receptor signaling pathway GO:0030521 47 35 0,000 0,03494856 0,0432031 ! cytokinesis GO:0000910 38 35 0,000 0,03494856 0,04318847 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,03494856 0,04317384 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,03592988 0,04437109 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,03592988 0,04435608 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,03592988 0,04434107 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,03592988 0,04432608 ! SMAD binding GO:0046332 39 36 0,000 0,03592988 0,04431109 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,03592988 0,04429612 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,03592988 0,04428115 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,03592988 0,0442662 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,03592988 0,04425125 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,03592988 0,04423632 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,03592988 0,04422139 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,03592988 0,04420648 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,03592988 0,04419158 ! cellular response to extracellular stimulus GO:0031668 37 36 0,000 0,03592988 0,04417668 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,03592988 0,0441618 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,03592988 0,04414692 ! positive regulation of mast cell proliferation GO:0070668 43 36 0,000 0,03592988 0,04413206 GO:0050671|positive regulation of lymphocyte proliferation, ! maintenance of location in cell GO:0051651 38 36 0,000 0,03592988 0,0441172 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,03691026 0,04530573 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,03691026 0,04529049 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,03691026 0,04527526 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,03691026 0,04526004 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,03691026 0,04524483 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,03691026 0,04522963 ! endoribonuclease activity GO:0004521 48 37 0,000 0,03691026 0,04521445 ! hindbrain development GO:0030902 43 37 0,000 0,03691026 0,04519927 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,03691026 0,0451841 ! pigmentation GO:0043473 51 37 0,000 0,03691026 0,04516894 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,03691026 0,0451538 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,03691026 0,04513866 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,03691026 0,04512353 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,03691026 0,04510842 ! sensory perception of taste GO:0050909 37 37 0,000 0,03691026 0,04509331 ! cell junction organization GO:0034330 44 37 0,000 0,03691026 0,04507821 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,03691026 0,04506313 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,03691026 0,04504805 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,03691026 0,04503298 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,03691026 0,04501793 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,03691026 0,04500288 ! coated pit GO:0005905 44 37 0,000 0,03691026 0,04498785 ! positive regulation of leukocyte proliferation GO:0070665 47 37 0,000 0,03691026 0,04497282 GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,03788969 0,04615078 ! regulation of translational initiation GO:0006446 50 38 0,000 0,03788969 0,04613538 ! negative regulation of binding GO:0051100 44 38 0,000 0,03788969 0,04611998 ! organic ether metabolic process GO:0018904 50 38 0,000 0,03788969 0,0461046 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,03788969 0,04608923 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,03788969 0,04607386 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,03788969 0,04605851 ! hydro-lyase activity GO:0016836 44 38 0,000 0,03788969 0,04604317 ! synapse organization GO:0050808 43 38 0,000 0,03788969 0,04602783 ! viral infectious cycle GO:0019058 40 38 0,000 0,03788969 0,04601251 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,03788969 0,0459972 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,03788969 0,0459819 ! organic anion transport GO:0015711 42 38 0,000 0,03788969 0,04596661 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,03788969 0,04595133 ! monosaccharide binding GO:0048029 41 38 0,000 0,03788969 0,04593605 ! muscle fiber development GO:0048747 42 38 0,000 0,03788969 0,04592079 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,03788969 0,04590554 ! phagocytosis GO:0006909 44 38 0,000 0,03788969 0,0458903 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,03788969 0,04587507 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,03788969 0,04585985 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,03788969 0,04584464 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,03788969 0,04582944 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,03788969 0,04581425 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,03788969 0,04579907 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,03788969 0,0457839 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,03886818 0,0469507 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,03886818 0,04693516 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,03886818 0,04691963 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,03886818 0,0469041 ! T cell differentiation GO:0030217 64 39 0,000 0,03886818 0,04688859 ! cell fate specification GO:0001708 55 39 0,000 0,03886818 0,04687309 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,03886818 0,0468576 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,03886818 0,04684212 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,03886818 0,04682665 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,03886818 0,04681119 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,03886818 0,04679575 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,03886818 0,04678031 ! amine receptor activity GO:0008227 48 39 0,000 0,03886818 0,04676488 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,03886818 0,04674946 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,03886818 0,04673405 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,03886818 0,04671865 ! double-strand break repair GO:0006302 70 39 0,000 0,03886818 0,04670326 ! pigment metabolic process GO:0042440 43 39 0,000 0,03886818 0,04668789 ! RNA modification GO:0009451 39 39 0,000 0,03886818 0,04667252 ! damaged DNA binding GO:0003684 51 40 0,000 0,03984572 0,0478306 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,03984572 0,04781486 ! peroxisomal membrane GO:0005778 44 40 0,000 0,03984572 0,04779914 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,03984572 0,04778343 ! positive regulation of cell development GO:0010720 43 40 0,000 0,03984572 0,04776773 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,03984572 0,04775203 ! biopolymer methylation GO:0043414 45 40 0,000 0,03984572 0,04773635 ! neuron migration GO:0001764 43 40 0,000 0,03984572 0,04772068 ! regulation of protein secretion GO:0050708 45 40 0,000 0,03984572 0,04770502 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,03984572 0,04768937 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,03984572 0,04767373 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,03984572 0,04765809 ! positive regulation of defense response GO:0031349 41 40 0,000 0,03984572 0,04764247 ! mammary gland development GO:0030879 47 40 0,000 0,03984572 0,04762686 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,03984572 0,04761126 ! neuropeptide binding GO:0042923 42 40 0,000 0,03984572 0,04759567 ! regulation of tube size GO:0035150 44 40 0,000 0,03984572 0,04758009 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,03984572 0,04756453 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,03984572 0,04754897 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,03984572 0,04753342 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,03984572 0,04751788 ! chromatin remodeling GO:0006338 44 40 0,000 0,03984572 0,04750235 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,03984572 0,04748683 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,04082232 0,04863483 ! keratin filament GO:0045095 44 41 0,000 0,04082232 0,04861895 ! induction of apoptosis by intracellular signals GO:0008629 56 41 0,000 0,04082232 0,04860308 ! peptide metabolic process GO:0006518 42 41 0,000 0,04082232 0,04858722 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,04082232 0,04857137 ! late endosome membrane GO:0031902 45 41 0,000 0,04082232 0,04855554 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,04082232 0,04853971 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,04082232 0,0485239 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,04082232 0,04850809 ! lamellipodium GO:0030027 56 41 0,000 0,04082232 0,04849229 ! glycolysis GO:0006096 43 41 0,000 0,04082232 0,04847651 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,04082232 0,04846073 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,04082232 0,04844497 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,04082232 0,04842921 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,04179798 0,04957056 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,04179798 0,04955445 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,04179798 0,04953835 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,04179798 0,04952226 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,04179798 0,04950618 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,04179798 0,04949012 ! nuclear export GO:0051168 46 42 0,000 0,04179798 0,04947406 ! developmental growth GO:0048589 45 42 0,000 0,04179798 0,04945801 ! structural constituent of muscle GO:0008307 46 42 0,000 0,04179798 0,04944197 ! mitochondrial transport GO:0006839 45 42 0,000 0,04179798 0,04942595 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,04179798 0,04940993 ! metal cluster binding GO:0051540 47 42 0,000 0,04179798 0,04939393 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,04179798 0,04937793 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,04179798 0,04936194 ! RNA catabolic process GO:0006401 49 43 0,000 0,04277271 0,05049671 ! ear morphogenesis GO:0042471 56 43 0,000 0,04277271 0,05048037 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,04277271 0,05046405 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,04277271 0,05044773 ! positive regulation of growth GO:0045927 47 43 0,000 0,04277271 0,05043142 ! cell recognition GO:0008037 51 43 0,000 0,04277271 0,05041513 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,04277271 0,05039885 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,04277271 0,05038257 ! gliogenesis GO:0042063 46 43 0,000 0,04277271 0,05036631 ! endosome transport GO:0016197 48 43 0,000 0,04277271 0,05035006 ! striated muscle contraction GO:0006941 45 43 0,000 0,04277271 0,05033382 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,04277271 0,05031758 ! antioxidant activity GO:0016209 53 43 0,000 0,04277271 0,05030136 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,04277271 0,05028515 ! activation of caspase activity GO:0006919 60 43 0,000 0,04277271 0,05026895 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,04277271 0,05025276 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,04277271 0,05023658 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,04374649 0,05136375 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,04374649 0,05134723 ! negative regulation of cell migration GO:0030336 53 44 0,000 0,04374649 0,05133071 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,04374649 0,05131421 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,04374649 0,05129771 ! chemokine activity GO:0008009 48 44 0,000 0,04374649 0,05128123 ! ruffle GO:0001726 50 44 0,000 0,04374649 0,05126476 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,04374649 0,05124829 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,04374649 0,05123184 ! cartilage development GO:0051216 48 44 0,000 0,04374649 0,0512154 ! membrane fusion GO:0006944 52 44 0,000 0,04374649 0,05119897 ! channel regulator activity GO:0016247 54 44 0,000 0,04374649 0,05118255 ! excretion GO:0007588 53 44 0,000 0,04374649 0,05116614 ! male sex differentiation GO:0046661 52 44 0,000 0,04374649 0,05114974 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,04374649 0,05113335 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,04374649 0,05111697 ! amino acid activation GO:0043038 45 44 0,000 0,04374649 0,0511006 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,04374649 0,05108425 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,04471933 0,05220356 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,04471933 0,05218686 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,04471933 0,05217017 ! organellar ribosome GO:0000313 46 45 0,000 0,04471933 0,05215349 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,04471933 0,05213682 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,04471933 0,05212016 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,04471933 0,05210352 ! transport vesicle GO:0030133 53 45 0,000 0,04471933 0,05208688 ! regulation of endocytosis GO:0030100 52 45 0,000 0,04471933 0,05207026 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,04471933 0,05205364 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,04471933 0,05203704 ! nuclear matrix GO:0016363 56 45 0,000 0,04471933 0,05202044 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,04471933 0,05200386 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,04471933 0,05198729 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,04471933 0,05197073 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,04471933 0,05195418 ! coated vesicle membrane GO:0030662 52 45 0,000 0,04471933 0,05193764 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,04471933 0,05192111 ! synaptosome GO:0019717 50 45 0,000 0,04471933 0,05190459 ! chemokine receptor binding GO:0042379 50 45 0,000 0,04471933 0,05188808 ! regulation of action potential GO:0001508 56 46 0,000 0,04569124 0,05299893 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,04569124 0,05298208 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,04569124 0,05296525 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,04569124 0,05294842 ! eye morphogenesis GO:0048592 57 46 0,000 0,04569124 0,05293161 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,04569124 0,0529148 ! methylation GO:0032259 51 46 0,000 0,04569124 0,05289801 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,04569124 0,05288123 ! regulation of ion transport GO:0043269 54 46 0,000 0,04569124 0,05286445 ! leukocyte migration GO:0050900 49 46 0,000 0,04569124 0,05284769 ! neuromuscular process GO:0050905 56 46 0,000 0,04569124 0,05283094 ! sulfotransferase activity GO:0008146 54 46 0,000 0,04569124 0,0528142 ! JNK cascade GO:0007254 48 46 0,000 0,04569124 0,05279747 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,04569124 0,05278076 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,0466622 0,05388532 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,0466622 0,05386827 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,0466622 0,05385122 ! microtubule binding GO:0008017 61 47 0,000 0,0466622 0,05383419 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,0466622 0,05381717 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,0466622 0,05380016 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,0466622 0,05378317 ! viral reproductive process GO:0022415 53 47 0,000 0,0466622 0,05376618 ! RNA elongation GO:0006354 52 47 0,000 0,0466622 0,0537492 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,0466622 0,05373223 ! mRNA binding GO:0003729 65 47 0,000 0,0466622 0,05371528 ! response to insulin stimulus GO:0032868 57 47 0,000 0,0466622 0,05369833 ! axon GO:0030424 53 48 0,000 0,04763224 0,05479735 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,04763224 0,05478008 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,04763224 0,05476281 ! proteasome complex GO:0000502 50 48 0,000 0,04763224 0,05474556 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,04763224 0,05472831 ! protein homooligomerization GO:0051260 63 48 0,000 0,04763224 0,05471108 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,04763224 0,05469386 ! kinetochore GO:0000776 69 48 0,000 0,04763224 0,05467665 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,04763224 0,05465945 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,04763224 0,05464226 ! growth factor receptor binding GO:0070851 58 48 0,000 0,04763224 0,05462509 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,04763224 0,05460792 ! inner ear development GO:0048839 60 48 0,000 0,04763224 0,05459076 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,04763224 0,05457362 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,04763224 0,05455648 ! B cell mediated immunity GO:0019724 53 48 0,000 0,04763224 0,05453936 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,04763224 0,05452225 ! regulation of cell shape GO:0008360 55 48 0,000 0,04763224 0,05450514 ! protein N-terminus binding GO:0047485 57 48 0,000 0,04763224 0,05448805 ! establishment of organelle localization GO:0051656 58 48 0,000 0,04763224 0,05447097 ! cell cortex part GO:0044448 54 48 0,000 0,04763224 0,0544539 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,04860133 0,05554438 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,04860133 0,05552699 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,04860133 0,0555096 ! response to temperature stimulus GO:0009266 57 49 0,000 0,04860133 0,05549223 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,04860133 0,05547486 ! lipid modification GO:0030258 55 49 0,000 0,04860133 0,05545751 ! synaptic vesicle GO:0008021 56 49 0,000 0,04860133 0,05544017 ! regulation of gene expression, epigenetic GO:0040029 64 49 0,000 0,04860133 0,05542284 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,04860133 0,05540552 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,04860133 0,05538821 ! maintenance of location GO:0051235 62 49 0,000 0,04860133 0,05537091 ! negative regulation of cell motion GO:0051271 60 49 0,000 0,04860133 0,05535363 ! regulation of actin filament length GO:0030832 62 49 0,000 0,04860133 0,05533635 ! nuclear periphery GO:0034399 60 49 0,000 0,04860133 0,05531908 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,04860133 0,05530183 ! negative regulation of cytoskeleton organization GO:0051494 73 49 0,000 0,04860133 0,05528459 ! nucleotide-excision repair GO:0006289 53 49 0,000 0,04860133 0,05526735 ! regulation of mast cell proliferation GO:0070666 57 49 0,000 0,04860133 0,05525013 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,0495695 0,05633319 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,0495695 0,05631564 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,0495695 0,05629811 ! glucose catabolic process GO:0006007 54 50 0,000 0,0495695 0,05628059 ! aging GO:0007568 92 50 0,000 0,0495695 0,05626308 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,0495695 0,05624558 ! heart morphogenesis GO:0003007 57 50 0,000 0,0495695 0,05622809 ! integrin binding GO:0005178 56 50 0,000 0,0495695 0,05621061 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,0495695 0,05619314 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,05053673 0,05727182 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,05053673 0,05725403 ! regulation of ossification GO:0030278 59 51 0,000 0,05053673 0,05723626 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,05053673 0,05721849 ! positive regulation of organelle organization GO:0010638 69 51 0,000 0,05053673 0,05720074 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,05053673 0,057183 ! endocrine system development GO:0035270 55 51 0,000 0,05053673 0,05716526 ! germ cell development GO:0007281 56 51 0,000 0,05053673 0,05714754 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,05150302 0,0582222 ! regulation of cellular component size GO:0032535 66 52 0,000 0,05150302 0,05820416 ! carbohydrate transport GO:0008643 57 52 0,000 0,05150302 0,05818614 ! regulation of lymphocyte proliferation GO:0050670 61 52 0,000 0,05150302 0,05816812 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,05150302 0,05815012 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,05150302 0,05813213 ! cell maturation GO:0048469 68 52 0,000 0,05150302 0,05811415 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,05150302 0,05809618 ! vesicle organization GO:0016050 59 52 0,000 0,05150302 0,05807822 ! kidney development GO:0001822 55 52 0,000 0,05150302 0,05806027 ! cellular component disassembly GO:0022411 69 52 0,000 0,05150302 0,05804233 ! cell redox homeostasis GO:0045454 57 52 0,000 0,05150302 0,05802441 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,05150302 0,05800649 ! lipid transporter activity GO:0005319 58 52 0,000 0,05150302 0,05798859 ! cytokine receptor activity GO:0004896 54 52 0,000 0,05150302 0,0579707 ! antiporter activity GO:0015297 53 52 0,000 0,05150302 0,05795282 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,05246839 0,05902087 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,05246839 0,05900268 ! keratinocyte differentiation GO:0030216 60 53 0,000 0,05246839 0,05898449 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,05246839 0,05896632 ! basement membrane GO:0005604 55 53 0,000 0,05246839 0,05894816 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,05246839 0,05893001 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,05246839 0,05891188 ! viral reproduction GO:0016032 59 53 0,000 0,05246839 0,05889375 ! chloride transport GO:0006821 60 53 0,000 0,05246839 0,05887563 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,05246839 0,05885753 ! regulation of protein catabolic process GO:0042176 56 53 0,000 0,05246839 0,05883944 ! regulation of DNA replication GO:0006275 75 53 0,000 0,05246839 0,05882135 ! DNA catabolic process GO:0006308 57 53 0,000 0,05246839 0,05880328 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,05246839 0,05878522 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,05246839 0,05876717 ! regulation of leukocyte proliferation GO:0070663 65 53 0,000 0,05246839 0,05874914 GO:0032944|regulation of mononuclear cell proliferation, ! single fertilization GO:0007338 58 53 0,000 0,05246839 0,05873111 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,05343282 0,05979231 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,05343282 0,05977398 ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,05343282 0,05975565 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,05343282 0,05973734 ! coated membrane GO:0048475 65 54 0,000 0,05343282 0,05971904 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,05343282 0,05970075 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,05343282 0,05968247 ! cellular defense response GO:0006968 61 54 0,000 0,05343282 0,0596642 ! gastrulation GO:0007369 62 54 0,000 0,05343282 0,05964594 ! dendrite GO:0030425 60 55 0,000 0,05439633 0,06070291 ! regulation of mitosis GO:0007088 79 55 0,000 0,05439633 0,06068434 GO:0051783|regulation of nuclear division, ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,05439633 0,06066579 ! respiratory chain GO:0070469 57 55 0,000 0,05439633 0,06064725 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,05439633 0,06062872 ! extracellular matrix organization GO:0030198 77 55 0,000 0,05439633 0,0606102 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,05439633 0,0605917 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,05439633 0,0605732 ! translation initiation factor activity GO:0003743 66 55 0,000 0,05439633 0,06055472 ! steroid hormone receptor signaling pathway GO:0030518 70 55 0,000 0,05439633 0,06053624 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,0553589 0,06158868 ! heat shock protein binding GO:0031072 62 56 0,000 0,0553589 0,0615699 ! late endosome GO:0005770 60 56 0,000 0,0553589 0,06155114 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,0553589 0,06153238 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,0553589 0,06151364 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,0553589 0,06149491 ! ribonuclease activity GO:0004540 67 56 0,000 0,0553589 0,06147619 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,0553589 0,06145748 ! mesoderm development GO:0007498 67 56 0,000 0,0553589 0,06143878 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,0553589 0,0614201 ! antigen processing and presentation GO:0019882 73 56 0,000 0,0553589 0,06140142 ! proton transport GO:0015992 59 56 0,000 0,0553589 0,06138276 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,05632055 0,06243007 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,05632055 0,06241111 ! diacylglycerol binding GO:0019992 65 57 0,000 0,05632055 0,06239216 ! B cell activation GO:0042113 63 57 0,000 0,05632055 0,06237321 ! small ribosomal subunit GO:0015935 58 57 0,000 0,05632055 0,06235429 ! detection of external stimulus GO:0009581 64 57 0,000 0,05632055 0,06233537 ! occluding junction GO:0070160 75 58 0,000 0,05728127 0,06337946 GO:0005923|tight junction, ! epidermal cell differentiation GO:0009913 66 58 0,000 0,05728127 0,06336024 ! hydrogen transport GO:0006818 61 58 0,000 0,05728127 0,06334104 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,05728127 0,06332184 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,05728127 0,06330266 ! response to nutrient GO:0007584 68 58 0,000 0,05728127 0,06328349 ! large ribosomal subunit GO:0015934 64 58 0,000 0,05728127 0,06326433 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,05728127 0,06324518 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,05728127 0,06322604 ! myosin complex GO:0016459 64 58 0,000 0,05728127 0,06320692 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,05824106 0,06424657 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,05824106 0,06422715 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,05824106 0,06420774 ! actin filament organization GO:0007015 65 59 0,000 0,05824106 0,06418834 ! regulation of heart contraction GO:0008016 71 59 0,000 0,05824106 0,06416895 ! hexose catabolic process GO:0019320 64 59 0,000 0,05824106 0,06414958 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,05824106 0,06413021 ! response to steroid hormone stimulus GO:0048545 74 59 0,000 0,05824106 0,06411086 ! cell projection assembly GO:0030031 79 59 0,000 0,05824106 0,06409152 ! regulation of cellular response to stress GO:0080135 79 59 0,000 0,05824106 0,0640722 ! appendage morphogenesis GO:0035107 68 59 0,000 0,05824106 0,06405288 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,05824106 0,06403357 ! fertilization GO:0009566 65 59 0,000 0,05824106 0,06401428 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,05824106 0,063995 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,05824106 0,06397573 ! adult behavior GO:0030534 72 59 0,000 0,05824106 0,06395647 ! organelle localization GO:0051640 70 59 0,000 0,05824106 0,06393723 ! positive regulation of secretion GO:0051047 66 60 0,000 0,05919993 0,06497032 ! molecular adaptor activity GO:0060090 73 60 0,000 0,05919993 0,06495078 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,05919993 0,06493125 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,05919993 0,06491174 ! copper ion binding GO:0005507 85 60 0,000 0,05919993 0,06489223 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,05919993 0,06487274 ! activation of immune response GO:0002253 72 60 0,000 0,05919993 0,06485326 ! regulation of caspase activity GO:0043281 78 60 0,000 0,05919993 0,06483379 ! appendage development GO:0048736 69 60 0,000 0,05919993 0,06481433 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,05919993 0,06479488 ! secondary metabolic process GO:0019748 67 60 0,000 0,05919993 0,06477545 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,06015787 0,06580387 ! ear development GO:0043583 76 61 0,000 0,06015787 0,06578415 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,06015787 0,06576444 ! learning or memory GO:0007611 79 61 0,000 0,06015787 0,06574473 ! Ras GTPase binding GO:0017016 78 61 0,000 0,06015787 0,06572504 ! camera-type eye development GO:0043010 69 61 0,000 0,06015787 0,06570537 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,06015787 0,0656857 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,06111489 0,06671069 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,06111489 0,06669073 ! lysosomal membrane GO:0005765 69 62 0,000 0,06111489 0,06667079 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,06111489 0,06665086 ! nuclear pore GO:0005643 79 62 0,000 0,06111489 0,06663094 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,06111489 0,06661103 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,06111489 0,06659114 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,06111489 0,06657125 ! chloride channel activity GO:0005254 72 62 0,000 0,06111489 0,06655138 ! cell soma GO:0043025 68 62 0,000 0,06111489 0,06653152 ! microtubule motor activity GO:0003777 94 62 0,000 0,06111489 0,06651167 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 0,000 0,06111489 0,06649183 ! focal adhesion GO:0005925 72 62 0,000 0,06111489 0,06647201 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,06111489 0,0664522 ! negative regulation of cell growth GO:0030308 69 63 0,000 0,06207099 0,06747168 ! FAD binding GO:0050660 71 63 0,000 0,06207099 0,06745158 ! regulation of endopeptidase activity GO:0052548 81 63 0,000 0,06207099 0,06743149 ! urogenital system development GO:0001655 75 63 0,000 0,06207099 0,06741142 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,06207099 0,06739136 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,06207099 0,0673713 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,06207099 0,06735127 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,06207099 0,06733124 ! regulation of immune effector process GO:0002697 81 63 0,000 0,06207099 0,06731122 ! negative regulation of protein kinase activity GO:0006469 78 64 0,000 0,06302616 0,06832672 ! respiratory tube development GO:0030323 92 64 0,000 0,06302616 0,06830642 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,06302616 0,06828614 ! tRNA processing GO:0008033 73 64 0,000 0,06302616 0,06826586 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,06302616 0,0682456 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,06302616 0,06822535 ! adaptive immune response GO:0002250 70 64 0,000 0,06302616 0,06820511 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,06302616 0,06818488 ! neurotransmitter transport GO:0006836 72 64 0,000 0,06302616 0,06816467 ! regulation of actin cytoskeleton organization GO:0032956 93 64 0,000 0,06302616 0,06814446 ! nuclear hormone receptor binding GO:0035257 79 64 0,000 0,06302616 0,06812427 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,06302616 0,0681041 ! negative regulation of cell size GO:0045792 71 65 0,000 0,06398041 0,06911476 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,06398041 0,0690943 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,06398041 0,06907385 ! positive regulation of lymphocyte activation GO:0051251 83 65 0,000 0,06398041 0,06905341 ! negative regulation of kinase activity GO:0033673 79 65 0,000 0,06398041 0,06903299 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,06398041 0,06901258 ! activation of MAPK activity GO:0000187 74 65 0,000 0,06398041 0,06899218 ! gonad development GO:0008406 71 65 0,000 0,06398041 0,06897179 ! acetyltransferase activity GO:0016407 73 65 0,000 0,06398041 0,06895141 ! protein import into nucleus GO:0006606 73 66 0,000 0,06493374 0,06995815 ! developmental maturation GO:0021700 85 66 0,000 0,06493374 0,06993749 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,06493374 0,06991685 ! tubulin binding GO:0015631 92 66 0,000 0,06493374 0,06989622 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,06493374 0,0698756 ! tube morphogenesis GO:0035239 84 66 0,000 0,06493374 0,06985499 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,06493374 0,0698344 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,06493374 0,06981382 ! regulation of peptidase activity GO:0052547 86 67 0,000 0,06588615 0,07081693 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,06588615 0,07079607 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,06588615 0,07077523 ! nuclear import GO:0051170 74 67 0,000 0,06588615 0,07075439 ! response to peptide hormone stimulus GO:0043434 79 67 0,000 0,06588615 0,07073357 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,06588615 0,07071276 ! regulation of actin filament-based process GO:0032970 96 67 0,000 0,06588615 0,07069196 ! chloride ion binding GO:0031404 79 67 0,000 0,06588615 0,07067118 ! humoral immune response GO:0006959 75 67 0,000 0,06588615 0,0706504 ! amine binding GO:0043176 77 67 0,000 0,06588615 0,07062964 ! female pregnancy GO:0007565 78 67 0,000 0,06588615 0,07060889 ! extrinsic to membrane GO:0019898 75 67 0,000 0,06588615 0,07058816 ! anion channel activity GO:0005253 77 67 0,000 0,06588615 0,07056743 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,06588615 0,07054672 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,06683764 0,07154452 ! amine catabolic process GO:0009310 73 68 0,000 0,06683764 0,07152353 ! negative regulation of organelle organization GO:0010639 93 68 0,000 0,06683764 0,07150255 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,06683764 0,07148159 ! cell-substrate junction GO:0030055 78 68 0,000 0,06683764 0,07146064 ! respiratory system development GO:0060541 96 68 0,000 0,06683764 0,0714397 ! mRNA transport GO:0051028 88 69 0,000 0,06778821 0,07243451 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,06778821 0,07241329 ! small GTPase binding GO:0031267 86 69 0,000 0,06778821 0,0723921 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,06778821 0,07237091 ! sarcomere GO:0030017 74 69 0,000 0,06778821 0,07234974 ! exocytosis GO:0006887 76 69 0,000 0,06778821 0,07232858 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,06778821 0,07230743 GO:0060538|skeletal muscle organ development, ! nucleosome assembly GO:0006334 87 69 0,000 0,06778821 0,07228629 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,06778821 0,07226517 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,06778821 0,07224406 ! amine biosynthetic process GO:0009309 78 70 0,000 0,06873787 0,07323474 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,06873787 0,07321336 ! early endosome GO:0005769 104 70 0,000 0,06873787 0,07319199 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,06873787 0,07317063 ! negative regulation of transferase activity GO:0051348 85 70 0,000 0,06873787 0,07314928 ! regulation of lipase activity GO:0060191 78 70 0,000 0,06873787 0,07312795 ! amino acid transport GO:0006865 76 70 0,000 0,06873787 0,07310663 ! chromatin assembly GO:0031497 88 70 0,000 0,06873787 0,07308532 ! hormone receptor binding GO:0051427 85 70 0,000 0,06873787 0,07306403 ! calcium channel activity GO:0005262 86 70 0,000 0,06873787 0,07304275 ! axon guidance GO:0007411 87 70 0,000 0,06873787 0,07302147 ! cell cortex GO:0005938 77 70 0,000 0,06873787 0,07300022 ! nuclear chromosome part GO:0044454 94 70 0,000 0,06873787 0,07297897 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,06968661 0,07396472 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,06968661 0,07394321 ! protein localization in nucleus GO:0034504 78 71 0,000 0,06968661 0,07392171 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,06968661 0,07390022 ! pore complex GO:0046930 89 72 0,000 0,07063443 0,07488358 ! response to hypoxia GO:0001666 84 72 0,000 0,07063443 0,07486183 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,07063443 0,07484008 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,07063443 0,07481835 ! regulation of lyase activity GO:0051339 85 72 0,000 0,07063443 0,07479663 ! acute inflammatory response GO:0002526 91 72 0,000 0,07063443 0,07477493 ! apical junction complex GO:0043296 90 72 0,000 0,07063443 0,07475324 ! phospholipase activity GO:0004620 99 72 0,000 0,07063443 0,07473156 ! membrane raft GO:0045121 81 72 0,000 0,07063443 0,07470989 ! regulation of neurological system process GO:0031644 91 72 0,000 0,07063443 0,07468823 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,07063443 0,07466659 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,07158134 0,07564563 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,07158134 0,07562373 ! protein transporter activity GO:0008565 80 73 0,000 0,07158134 0,07560183 ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,07158134 0,07557995 ! exopeptidase activity GO:0008238 81 73 0,000 0,07158134 0,07555808 ! digestion GO:0007586 81 73 0,000 0,07158134 0,07553622 ! positive regulation of leukocyte activation GO:0002696 92 73 0,000 0,07158134 0,07551438 ! regulation of Rho protein signal transduction GO:0035023 88 73 0,000 0,07158134 0,07549255 ! cell-matrix adhesion GO:0007160 102 74 0,000 0,07252733 0,07646812 ! response to oxygen levels GO:0070482 86 74 0,000 0,07252733 0,07644603 ! potassium channel complex GO:0034705 84 74 0,000 0,07252733 0,07642395 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,07252733 0,07640188 ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,07252733 0,07637982 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,07252733 0,07635778 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,07252733 0,07633575 ! blood coagulation GO:0007596 90 74 0,000 0,07252733 0,07631373 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,07252733 0,07629173 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,07252733 0,07626974 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,07252733 0,07624776 ! ubiquitin ligase complex GO:0000151 91 74 0,000 0,07252733 0,07622579 ! cell projection part GO:0044463 80 74 0,000 0,07252733 0,07620383 ! meiosis GO:0007126 108 75 0,000 0,07347241 0,07717459 GO:0051327|M phase of meiotic cell cycle, ! regulation of DNA binding GO:0051101 94 75 0,000 0,07347241 0,07715238 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,07347241 0,07713018 ! regulation of cell cycle process GO:0010564 113 75 0,000 0,07347241 0,07710799 ! positive regulation of cell activation GO:0050867 94 75 0,000 0,07347241 0,07708581 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,07347241 0,07706365 ! regulation of blood pressure GO:0008217 82 75 0,000 0,07347241 0,0770415 ! transcription initiation GO:0006352 84 75 0,000 0,07347241 0,07701936 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,07347241 0,07699723 ! neuropeptide signaling pathway GO:0007218 85 76 0,000 0,07441658 0,0779643 ! negative regulation of growth GO:0045926 85 76 0,000 0,07441658 0,07794192 ! defense response to bacterium GO:0042742 81 76 0,000 0,07441658 0,07791954 ! regulation of lipid metabolic process GO:0019216 98 76 0,000 0,07441658 0,07789719 ! cell leading edge GO:0031252 97 76 0,000 0,07441658 0,07787484 ! meiotic cell cycle GO:0051321 109 76 0,000 0,07441658 0,07785251 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,07441658 0,07783019 ! condensed chromosome GO:0000793 106 76 0,000 0,07441658 0,07780788 ! protein-DNA complex GO:0032993 93 76 0,000 0,07441658 0,07778559 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,07441658 0,0777633 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,07441658 0,07774103 ! cytosolic ribosome GO:0022626 82 76 0,000 0,07441658 0,07771878 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,07441658 0,07769654 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,07535984 0,07865885 ! nucleosome organization GO:0034728 96 77 0,000 0,07535984 0,07863635 ! alcohol catabolic process GO:0046164 84 77 0,000 0,07535984 0,07861387 ! vacuolar membrane GO:0005774 86 77 0,000 0,07535984 0,07859139 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,07535984 0,07856893 ! regulation of Ras GTPase activity GO:0032318 88 77 0,000 0,07535984 0,07854648 ! establishment of RNA localization GO:0051236 97 77 0,000 0,07535984 0,07852405 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! myofibril GO:0030016 82 77 0,000 0,07535984 0,07850163 ! protein oligomerization GO:0051259 93 77 0,000 0,07535984 0,07847922 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,07630219 0,07943789 ! endonuclease activity GO:0004519 111 78 0,000 0,07630219 0,07941523 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,07630219 0,07939258 ! inorganic anion transport GO:0015698 87 78 0,000 0,07630219 0,07936994 ! regulation of protein transport GO:0051223 85 78 0,000 0,07630219 0,07934731 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,07630219 0,0793247 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,07630219 0,0793021 ! carboxylesterase activity GO:0004091 93 78 0,000 0,07630219 0,07927951 ! protein ubiquitination GO:0016567 95 78 0,000 0,07630219 0,07925694 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,07630219 0,07923438 ! contractile fiber part GO:0044449 83 78 0,000 0,07630219 0,07921183 ! RNA localization GO:0006403 99 79 0,000 0,07724362 0,08016635 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,07724362 0,08014355 ! vitamin metabolic process GO:0006766 86 79 0,000 0,07724362 0,08012077 ! T cell activation GO:0042110 120 79 0,000 0,07724362 0,08009799 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,07724362 0,08007523 ! phosphoinositide binding GO:0035091 99 79 0,000 0,07724362 0,08005248 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,07818415 0,0810042 ! eye development GO:0001654 93 80 0,000 0,07818415 0,0809812 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,07818415 0,08095821 ! rhythmic process GO:0048511 90 80 0,000 0,07818415 0,08093524 ! regulation of catabolic process GO:0009894 87 80 0,000 0,07818415 0,08091228 ! SH3 domain binding GO:0017124 95 80 0,000 0,07818415 0,08088933 ! hemostasis GO:0007599 96 80 0,000 0,07818415 0,0808664 ! chromosome, centromeric region GO:0000775 119 80 0,000 0,07818415 0,08084347 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,07818415 0,08082057 ! cell-substrate adhesion GO:0031589 109 80 0,000 0,07818415 0,08079767 ! rRNA processing GO:0006364 84 80 0,000 0,07818415 0,08077479 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,07912377 0,0817224 ! vacuolar part GO:0044437 91 81 0,000 0,07912377 0,08169927 ! ossification GO:0001503 111 82 0,000 0,08006248 0,08264514 ! mitochondrion organization GO:0007005 104 82 0,000 0,08006248 0,08262176 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,08006248 0,0825984 ! forebrain development GO:0030900 93 82 0,000 0,08006248 0,08257504 ! external side of plasma membrane GO:0009897 105 82 0,000 0,08006248 0,0825517 ! cellular respiration GO:0045333 85 82 0,000 0,08006248 0,08252838 ! heparin binding GO:0008201 108 82 0,000 0,08006248 0,08250507 ! microtubule-based movement GO:0007018 119 83 0,000 0,08100029 0,08344791 ! nuclear speck GO:0016607 99 83 0,000 0,08100029 0,08342435 ! rRNA metabolic process GO:0016072 88 83 0,000 0,08100029 0,0834008 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,08100029 0,08337727 GO:0070035|purine NTP-dependent helicase activity, ! regulation of cell adhesion GO:0030155 98 83 0,000 0,08100029 0,08335375 ! regulation of T cell activation GO:0050863 104 83 0,000 0,08100029 0,08333024 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,08100029 0,08330675 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,08100029 0,08328327 ! contractile fiber GO:0043292 88 83 0,000 0,08100029 0,0832598 ! bone development GO:0060348 112 83 0,000 0,08100029 0,08323635 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,08100029 0,08321291 ! regulation of membrane potential GO:0042391 98 83 0,000 0,08100029 0,08318948 ! cilium GO:0005929 88 83 0,000 0,08100029 0,08316607 ! regulation of DNA metabolic process GO:0051052 139 84 0,000 0,08193719 0,08410435 ! regulation of defense response GO:0031347 98 84 0,000 0,08193719 0,08408069 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,08193719 0,08405705 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,08193719 0,08403341 ! DNA recombination GO:0006310 147 84 0,000 0,08193719 0,0840098 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,08287318 0,08494559 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,08287318 0,08492173 ! monooxygenase activity GO:0004497 92 85 0,000 0,08287318 0,08489788 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,08287318 0,08487405 ! protein binding, bridging GO:0030674 104 85 0,000 0,08287318 0,08485023 ! negative regulation of transport GO:0051051 98 86 0,000 0,08380827 0,08578355 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,08380827 0,08575949 ! Golgi vesicle transport GO:0048193 98 86 0,000 0,08380827 0,08573544 ! lipase activity GO:0016298 114 86 0,000 0,08380827 0,0857114 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,08380827 0,08568738 ! adherens junction GO:0005912 100 86 0,000 0,08380827 0,08566337 ! microtubule cytoskeleton organization GO:0000226 113 87 0,000 0,08474246 0,08659397 ! leukocyte differentiation GO:0002521 118 87 0,000 0,08474246 0,08656972 ! pigment granule GO:0048770 101 87 0,000 0,08474246 0,08654549 GO:0042470|melanosome, ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,08474246 0,08652127 ! organelle outer membrane GO:0031968 102 88 0,000 0,08567574 0,08744967 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,08567574 0,0874252 ! growth factor binding GO:0019838 102 88 0,000 0,08567574 0,08740076 ! protein processing GO:0016485 100 88 0,000 0,08567574 0,08737632 ! gland development GO:0048732 108 89 0,000 0,08660813 0,08830253 ! ATP metabolic process GO:0046034 100 90 0,000 0,08753961 0,08922729 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,08753961 0,08920237 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,08753961 0,08917746 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,08753961 0,08915257 ! sterol metabolic process GO:0016125 102 90 0,000 0,08753961 0,08912768 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,08753961 0,08910281 ! anion binding GO:0043168 104 90 0,000 0,08753961 0,08907796 ! amine transport GO:0015837 97 90 0,000 0,08753961 0,08905312 ! response to virus GO:0009615 109 90 0,000 0,08753961 0,08902829 ! outer membrane GO:0019867 104 90 0,000 0,08753961 0,08900348 ! extracellular matrix part GO:0044420 111 90 0,000 0,08753961 0,08897868 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,08847019 0,08989951 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,08847019 0,08987448 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,08847019 0,08984946 ! sulfur metabolic process GO:0006790 98 91 0,000 0,08847019 0,08982445 ! sex differentiation GO:0007548 103 91 0,000 0,08847019 0,08979946 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 0,000 0,08847019 0,08977448 ! hormone metabolic process GO:0042445 107 91 0,000 0,08847019 0,08974951 ! regulation of protein localization GO:0032880 99 91 0,000 0,08847019 0,08972456 ! detection of stimulus GO:0051606 100 91 0,000 0,08847019 0,08969963 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,08939987 0,09061704 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,08939987 0,09059187 ! regulation of cellular component biogenesis GO:0044087 115 92 0,000 0,08939987 0,09056671 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,08939987 0,09054157 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,08939987 0,09051644 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,08939987 0,09049133 ! regulation of GTPase activity GO:0043087 105 92 0,000 0,08939987 0,09046622 ! extracellular structure organization GO:0043062 119 92 0,000 0,08939987 0,09044114 ! protein import GO:0017038 102 93 0,000 0,09032866 0,0913554 ! regulation of cytoskeleton organization GO:0051493 133 93 0,000 0,09032866 0,09133008 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,09032866 0,09130478 ! response to nutrient levels GO:0031667 105 93 0,000 0,09032866 0,09127949 ! Ras protein signal transduction GO:0007265 118 93 0,000 0,09032866 0,09125421 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,09032866 0,09122894 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,09125654 0,09214057 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,09125654 0,09211507 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,09125654 0,09208959 GO:0060429|epithelium development, ! anchoring junction GO:0070161 108 94 0,000 0,09125654 0,09206412 ! neurotransmitter binding GO:0042165 105 94 0,000 0,09125654 0,09203867 ! homophilic cell adhesion GO:0007156 107 95 0,000 0,09218354 0,09294791 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,09218354 0,09292223 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,09218354 0,09289656 ! protein localization in organelle GO:0033365 104 95 0,000 0,09218354 0,0928709 ! Wnt receptor signaling pathway GO:0016055 121 95 0,000 0,09218354 0,09284526 ! immune effector process GO:0002252 110 95 0,000 0,09218354 0,09281963 ! apical plasma membrane GO:0016324 105 95 0,000 0,09218354 0,09279402 ! translational elongation GO:0006414 104 96 0,000 0,09310963 0,09370039 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,09310963 0,09367455 ! in utero embryonic development GO:0001701 110 96 0,000 0,09310963 0,09364873 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,09310963 0,09362291 ! receptor complex GO:0043235 131 96 0,000 0,09310963 0,09359712 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,09310963 0,09357133 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,09310963 0,09354556 ! electron transport chain GO:0022900 104 97 0,000 0,09403483 0,09444908 ! microtubule associated complex GO:0005875 135 97 0,000 0,09403483 0,09442308 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,09403483 0,0943971 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,09403483 0,09437113 ! carboxylic acid binding GO:0031406 108 97 0,000 0,09403483 0,09434518 ! protein maturation GO:0051604 109 97 0,000 0,09403483 0,09431924 ! intermediate filament GO:0005882 102 98 0,000 0,09495914 0,09522016 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,09495914 0,09519399 ! cell fate commitment GO:0045165 118 98 0,000 0,09495914 0,09516784 ! negative regulation of cellular component organization GO:0051129 132 99 0,000 0,09588255 0,09606689 ! hormone activity GO:0005179 113 99 0,000 0,09588255 0,09604051 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,09588255 0,09601415 ! unfolded protein binding GO:0051082 118 100 0,000 0,09680507 0,09691133 ! nuclear chromosome GO:0000228 127 100 0,000 0,09680507 0,09688474 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,09680507 0,09685817 ! regulation of lymphocyte activation GO:0051249 123 100 0,000 0,09680507 0,09683161 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,09680507 0,09680507