pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/8893-10-real-Parker_GPL1390-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL1390.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 51 50 3,000 8,131E-09 2,904E-05 ! protein kinase regulator activity GO:0019887 64 64 3,000 2,236E-08 3,993E-05 ! kinase regulator activity GO:0019207 77 77 3,000 4,75E-08 5,654E-05 ! negative regulation of translation GO:0017148 20 18 2,000 8,541E-08 7,625E-05 ! G1/S transition of mitotic cell cycle GO:0000082 47 46 2,000 1,578E-06 1,127E-03 ! positive regulation of translational initiation GO:0045948 5 5 1,000 2,578E-06 1,534E-03 ! negative regulation of protein ubiquitination GO:0031397 5 5 1,000 2,578E-06 1,315E-03 ! small-subunit processome GO:0032040 5 5 1,000 2,578E-06 1,151E-03 ! response to peptide hormone stimulus GO:0043434 60 55 2,000 2,72E-06 1,079E-03 ! translation initiation factor activity GO:0003743 58 58 2,000 3,197E-06 1,142E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 3,865E-06 1,255E-03 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 1,000 3,865E-06 1,15E-03 ! astrocyte development GO:0014002 6 6 1,000 3,865E-06 1,062E-03 ! cGMP-mediated signaling GO:0019934 6 6 1,000 3,865E-06 9,86E-04 ! response to unfolded protein GO:0006986 68 66 2,000 4,731E-06 1,126E-03 ! enoyl-CoA hydratase activity GO:0004300 7 7 1,000 5,41E-06 1,207E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 7 7 1,000 5,41E-06 1,136E-03 GO:0010921|regulation of phosphatase activity, ! negative regulation of translational initiation GO:0045947 7 7 1,000 5,41E-06 1,073E-03 ! regulation of focal adhesion formation GO:0051893 9 7 1,000 5,41E-06 1,017E-03 ! translation initiation factor binding GO:0031369 7 7 1,000 5,41E-06 9,66E-04 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 7 7 1,000 5,41E-06 9,2E-04 ! preribosome GO:0030684 7 7 1,000 5,41E-06 8,782E-04 ! response to protein stimulus GO:0051789 74 72 2,000 6,157E-06 9,559E-04 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 1,000 7,212E-06 1,073E-03 ! keratinocyte proliferation GO:0043616 8 8 1,000 7,212E-06 1,03E-03 ! astrocyte differentiation GO:0048708 8 8 1,000 7,212E-06 9,905E-04 ! interphase of mitotic cell cycle GO:0051329 84 82 2,000 9,119E-06 1,206E-03 GO:0051325|interphase, ! positive regulation of Rho GTPase activity GO:0032321 9 9 1,000 9,269E-06 1,182E-03 ! regulation of dephosphorylation GO:0035303 12 10 1,000 1,158E-05 1,426E-03 ! oligodendrocyte development GO:0014003 10 10 1,000 1,158E-05 1,379E-03 ! regulation of stress fiber formation GO:0051492 13 10 1,000 1,158E-05 1,334E-03 ! regulation of actin filament bundle formation GO:0032231 14 11 1,000 1,415E-05 1,579E-03 ! cyclin-dependent protein kinase regulator activity GO:0016538 11 11 1,000 1,415E-05 1,532E-03 ! translation factor activity, nucleic acid binding GO:0008135 99 96 2,000 1,466E-05 1,54E-03 ! positive regulation of Ras GTPase activity GO:0032320 12 12 1,000 1,698E-05 1,732E-03 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 12 12 1,000 1,698E-05 1,684E-03 ! negative regulation of caspase activity GO:0043154 12 12 1,000 1,698E-05 1,639E-03 ! positive regulation of translation GO:0045727 13 13 1,000 2,006E-05 1,885E-03 ! positive regulation of GTPase activity GO:0043547 14 13 1,000 2,006E-05 1,837E-03 ! positive regulation of cell growth GO:0030307 13 13 1,000 2,006E-05 1,791E-03 ! regulation of protein ubiquitination GO:0031396 13 13 1,000 2,006E-05 1,747E-03 ! oligodendrocyte differentiation GO:0048709 13 13 1,000 2,006E-05 1,706E-03 ! protein serine/threonine kinase inhibitor activity GO:0030291 14 14 1,000 2,34E-05 1,943E-03 ! release of cytochrome c from mitochondria GO:0001836 14 14 1,000 2,34E-05 1,899E-03 ! response to hexose stimulus GO:0009746 14 14 1,000 2,34E-05 1,857E-03 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! skin development GO:0043588 16 15 1,000 2,699E-05 2,095E-03 ! negative regulation of peptidase activity GO:0010466 16 15 1,000 2,699E-05 2,051E-03 ! positive regulation of cell size GO:0045793 16 16 1,000 3,084E-05 2,294E-03 ! glial cell development GO:0021782 17 17 1,000 3,494E-05 2,546E-03 ! regulation of Rho GTPase activity GO:0032319 17 17 1,000 3,494E-05 2,496E-03 ! response to carbohydrate stimulus GO:0009743 17 17 1,000 3,494E-05 2,447E-03 ! chaperone binding GO:0051087 18 18 1,000 3,93E-05 2,699E-03 ! ovarian follicle development GO:0001541 19 19 1,000 4,391E-05 2,959E-03 ! cellular response to unfolded protein GO:0034620 21 19 1,000 4,391E-05 2,904E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of cell-matrix adhesion GO:0001952 22 20 1,000 4,878E-05 3,167E-03 GO:0010810|regulation of cell-substrate adhesion, ! apoptotic mitochondrial changes GO:0008637 21 21 1,000 5,39E-05 3,437E-03 ! positive regulation of cell adhesion GO:0045785 23 22 1,000 5,927E-05 3,713E-03 ! translational initiation GO:0006413 23 23 1,000 6,49E-05 3,996E-03 ! NF-kappaB binding GO:0051059 23 23 1,000 6,49E-05 3,928E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 24 24 1,000 7,078E-05 4,212E-03 ! negative regulation of protein modification process GO:0031400 28 24 1,000 7,078E-05 4,143E-03 ! RNA export from nucleus GO:0006405 27 25 1,000 7,691E-05 4,43E-03 ! myelination GO:0042552 26 25 1,000 7,691E-05 4,359E-03 ! actin filament GO:0005884 28 25 1,000 7,691E-05 4,291E-03 ! fat cell differentiation GO:0045444 26 26 1,000 8,33E-05 4,576E-03 ! response to endoplasmic reticulum stress GO:0034976 29 26 1,000 8,33E-05 4,507E-03 ! response to heat GO:0009408 26 26 1,000 8,33E-05 4,44E-03 ! ovulation cycle process GO:0022602 27 27 1,000 8,994E-05 4,723E-03 ! ovulation cycle GO:0042698 28 28 1,000 9,683E-05 5,011E-03 ! ER-nuclear signaling pathway GO:0006984 31 28 1,000 9,683E-05 4,94E-03 ! ensheathment of neurons GO:0007272 29 28 1,000 9,683E-05 4,87E-03 GO:0008366|axon ensheathment, ! protein kinase inhibitor activity GO:0004860 28 28 1,000 9,683E-05 4,802E-03 ! kinase inhibitor activity GO:0019210 30 30 1,000 1,114E-04 5,448E-03 ! negative regulation of hydrolase activity GO:0051346 32 30 1,000 1,114E-04 5,374E-03 ! female gonad development GO:0008585 32 32 1,000 1,269E-04 6,043E-03 ! glial cell differentiation GO:0010001 33 33 1,000 1,351E-04 6,346E-03 ! intramolecular oxidoreductase activity GO:0016860 35 34 1,000 1,435E-04 6,654E-03 ! development of primary female sexual characteristics GO:0046545 34 34 1,000 1,435E-04 6,568E-03 GO:0046660|female sex differentiation, ! regulation of action potential in neuron GO:0019228 38 35 1,000 1,521E-04 6,876E-03 ! response to calcium ion GO:0051592 39 35 1,000 1,521E-04 6,79E-03 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 40 38 1,000 1,796E-04 7,918E-03 ! positive regulation of cell cycle GO:0045787 39 39 1,000 1,892E-04 8,241E-03 ! nuclear export GO:0051168 42 40 1,000 1,992E-04 8,568E-03 ! gliogenesis GO:0042063 40 40 1,000 1,992E-04 8,466E-03 ! protein serine/threonine phosphatase activity GO:0004722 42 40 1,000 1,992E-04 8,367E-03 ! response to insulin stimulus GO:0032868 45 40 1,000 1,992E-04 8,27E-03 ! regulation of translational initiation GO:0006446 41 41 1,000 2,093E-04 8,591E-03 ! hydro-lyase activity GO:0016836 44 41 1,000 2,093E-04 8,494E-03 ! positive regulation of growth GO:0045927 42 42 1,000 2,197E-04 8,816E-03 ! induction of apoptosis by intracellular signals GO:0008629 46 43 1,000 2,304E-04 9,141E-03 ! keratinocyte differentiation GO:0030216 46 43 1,000 2,304E-04 9,04E-03 ! regulation of action potential GO:0001508 50 45 1,000 2,524E-04 9,798E-03 ! response to temperature stimulus GO:0009266 45 45 1,000 2,524E-04 9,693E-03 ! epidermal cell differentiation GO:0009913 51 48 1,000 2,874E-04 0,01091742 ! protein N-terminus binding GO:0047485 51 48 1,000 2,874E-04 0,0108025 ! lamellipodium GO:0030027 53 49 1,000 2,995E-04 0,01114184 ! response to UV GO:0009411 50 49 1,000 2,995E-04 0,01102698 ! carbon-oxygen lyase activity GO:0016835 54 51 1,000 3,246E-04 0,01182685 ! DNA damage response, signal transduction GO:0042770 58 52 1,000 3,375E-04 0,01217237 ! positive regulation of protein amino acid phosphorylation GO:0001934 54 52 1,000 3,375E-04 0,01205065 ! positive regulation of phosphorylation GO:0042327 59 57 1,000 4,056E-04 0,01434129 ! positive regulation of phosphorus metabolic process GO:0010562 61 58 1,000 4,2E-04 0,01470386 GO:0045937|positive regulation of phosphate metabolic process, ! multicellular organism reproduction GO:0032504 62 60 1,000 4,495E-04 0,01558327 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of protein kinase activity GO:0006469 67 61 1,000 4,646E-04 0,01595226 ! gonad development GO:0008406 61 61 1,000 4,646E-04 0,01580033 ! negative regulation of kinase activity GO:0033673 68 62 1,000 4,799E-04 0,01616859 ! negative regulation of transferase activity GO:0051348 71 65 1,000 5,275E-04 0,01760402 ! rhythmic process GO:0048511 66 65 1,000 5,275E-04 0,01744102 ! response to metal ion GO:0010038 69 65 1,000 5,275E-04 0,01728101 ! positive regulation of protein modification process GO:0031401 69 65 1,000 5,275E-04 0,01712391 ! response to nutrient GO:0007584 67 66 1,000 5,438E-04 0,01749518 ! regulation of caspase activity GO:0043281 70 67 1,000 5,604E-04 0,01786763 ! regulation of actin cytoskeleton organization GO:0032956 74 68 1,000 5,772E-04 0,0182412 ! ribonucleoprotein complex assembly GO:0022618 69 68 1,000 5,772E-04 0,01808119 ! regulation of endopeptidase activity GO:0052548 72 69 1,000 5,943E-04 0,01845399 ! response to inorganic substance GO:0010035 74 70 1,000 6,116E-04 0,01882787 ! rRNA processing GO:0006364 70 70 1,000 6,116E-04 0,01866694 ! cell cortex GO:0005938 74 70 1,000 6,116E-04 0,01850875 ! reproductive structure development GO:0048608 71 71 1,000 6,292E-04 0,01888006 ! regulation of actin filament-based process GO:0032970 77 71 1,000 6,292E-04 0,01872272 ! rRNA metabolic process GO:0016072 73 73 1,000 6,65E-04 0,01962582 ! regulation of peptidase activity GO:0052547 78 74 1,000 6,833E-04 0,0200002 ! development of primary sexual characteristics GO:0045137 74 74 1,000 6,833E-04 0,0198376 ! regulation of Rho protein signal transduction GO:0035023 79 74 1,000 6,833E-04 0,01967762 ! establishment of RNA localization GO:0051236 78 75 1,000 7,018E-04 0,02004955 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! RNA localization GO:0006403 80 77 1,000 7,396E-04 0,02096135 ! regulation of cell adhesion GO:0030155 82 78 1,000 7,589E-04 0,02133777 ! regulation of Ras GTPase activity GO:0032318 84 80 1,000 7,981E-04 0,0222658 ! protein kinase binding GO:0019901 89 80 1,000 7,981E-04 0,02209319 ! mitochondrion organization GO:0007005 86 83 1,000 8,588E-04 0,02358987 ! cell leading edge GO:0031252 90 83 1,000 8,588E-04 0,02340979 ! regulation of membrane potential GO:0042391 92 84 1,000 8,795E-04 0,02379262 ! sex differentiation GO:0007548 86 86 1,000 9,216E-04 0,02474505 ! cell cycle arrest GO:0007050 92 87 1,000 9,43E-04 0,02513144 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 92 89 1,000 9,866E-04 0,026098 ! protein tyrosine phosphatase activity GO:0004725 104 92 1,000 1,054E-03 0,02766969 ! peroxisome GO:0005777 97 96 1,000 1,147E-03 0,0298893 GO:0042579|microbody, ! Wnt receptor signaling pathway GO:0016055 104 96 1,000 1,147E-03 0,02967271 ! response to nutrient levels GO:0031667 98 96 1,000 1,147E-03 0,02945924 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 101 97 1,000 1,171E-03 0,02985646 ! reproductive developmental process GO:0003006 97 97 1,000 1,171E-03 0,02964471 ! regulation of GTPase activity GO:0043087 104 97 1,000 1,171E-03 0,02943595 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 99 98 1,000 1,195E-03 0,02983095 ! regulation of cellular component biogenesis GO:0044087 106 99 1,000 1,219E-03 0,03022636 ! kinase binding GO:0019900 108 99 1,000 1,219E-03 0,03001791 ! tRNA transcription GO:0009304 5 5 0,000 2,712E-03 0,06633819 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 5 5 0,000 2,712E-03 0,06588691 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 2,712E-03 0,06544173 ! benzene and derivative metabolic process GO:0042537 5 5 0,000 2,712E-03 0,06500252 ! response to oxygen radical GO:0000305 5 5 0,000 2,712E-03 0,06456917 ! positive regulation of axon extension GO:0045773 6 5 0,000 2,712E-03 0,06414156 ! negative regulation of bone resorption GO:0045779 5 5 0,000 2,712E-03 0,06371958 ! positive regulation of lipid biosynthetic process GO:0046889 5 5 0,000 2,712E-03 0,06330311 ! regulation of interferon-beta production GO:0032648 6 5 0,000 2,712E-03 0,06289205 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! sodium-independent organic anion transmembrane transporter activity GO:0015347 6 5 0,000 2,712E-03 0,06248629 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 2,712E-03 0,06208574 ! negative regulation of transmembrane transport GO:0034763 5 5 0,000 2,712E-03 0,06169029 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! hypothalamus development GO:0021854 5 5 0,000 2,712E-03 0,06129984 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 2,712E-03 0,06091431 ! N-terminal protein lipidation GO:0006498 5 5 0,000 2,712E-03 0,0605336 ! glycolipid transport GO:0046836 5 5 0,000 2,712E-03 0,06015761 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 5 5 0,000 2,712E-03 0,05978627 ! phosphoinositide 3-kinase binding GO:0043548 5 5 0,000 2,712E-03 0,05941948 ! protein amino acid sulfation GO:0006477 5 5 0,000 2,712E-03 0,05905717 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 6 5 0,000 2,712E-03 0,05869925 ! embryonic camera-type eye development GO:0031076 7 5 0,000 2,712E-03 0,05834564 GO:0048596|embryonic camera-type eye morphogenesis, ! opioid peptide activity GO:0001515 5 5 0,000 2,712E-03 0,05799626 ! selenocysteine incorporation GO:0001514 5 5 0,000 2,712E-03 0,05765104 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 5 5 0,000 2,712E-03 0,05730991 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 5 5 0,000 2,712E-03 0,0569728 ! elastic fiber assembly GO:0048251 5 5 0,000 2,712E-03 0,05663962 ! regulation of mitochondrial membrane permeability GO:0046902 5 5 0,000 2,712E-03 0,05631032 ! neurofilament cytoskeleton organization GO:0060052 5 5 0,000 2,712E-03 0,05598483 ! ruffle membrane GO:0032587 5 5 0,000 2,712E-03 0,05566308 ! regulation of histone modification GO:0031056 5 5 0,000 2,712E-03 0,055345 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 2,712E-03 0,05503054 ! behavioral response to pain GO:0048266 5 5 0,000 2,712E-03 0,05471964 ! clathrin coat assembly GO:0048268 6 5 0,000 2,712E-03 0,05441222 ! Notch receptor processing GO:0007220 5 5 0,000 2,712E-03 0,05410824 ! cerebral cortex radially oriented cell migration GO:0021799 5 5 0,000 2,712E-03 0,05380764 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 6 5 0,000 2,712E-03 0,05351036 ! serotonin receptor signaling pathway GO:0007210 5 5 0,000 2,712E-03 0,05321635 ! oxidoreductase activity, oxidizing metal ions GO:0016722 5 5 0,000 2,712E-03 0,05292555 ! response to lipid GO:0033993 5 5 0,000 2,712E-03 0,05263791 ! cytoplasmic dynein complex GO:0005868 6 5 0,000 2,712E-03 0,05235338 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 2,712E-03 0,05207191 ! positive regulation of muscle cell differentiation GO:0051149 5 5 0,000 2,712E-03 0,05179345 ! smooth muscle cell differentiation GO:0051145 5 5 0,000 2,712E-03 0,05151795 ! exo-alpha-sialidase activity GO:0004308 5 5 0,000 2,712E-03 0,05124537 GO:0016997|alpha-sialidase activity, ! regulation of odontogenesis GO:0042481 5 5 0,000 2,712E-03 0,05097566 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 2,712E-03 0,05070877 ! formate-tetrahydrofolate ligase activity GO:0004329 5 5 0,000 2,712E-03 0,05044466 ! negative regulation of heart contraction GO:0045822 5 5 0,000 2,712E-03 0,05018329 ! ovulation from ovarian follicle GO:0001542 5 5 0,000 2,712E-03 0,04992462 ! DNA ligation during DNA repair GO:0051103 5 5 0,000 2,712E-03 0,04966859 ! 1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 5 5 0,000 2,712E-03 0,04941518 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 2,712E-03 0,04916434 ! negative regulation of endocytosis GO:0045806 5 5 0,000 2,712E-03 0,04891604 ! microfibril GO:0001527 5 5 0,000 2,712E-03 0,04867023 GO:0043205|fibril, ! parathyroid gland development GO:0060017 5 5 0,000 2,712E-03 0,04842688 ! toxin metabolic process GO:0009404 5 5 0,000 2,712E-03 0,04818595 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 2,712E-03 0,0479474 ! cytokine secretion GO:0050663 5 5 0,000 2,712E-03 0,04771121 ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 5 5 0,000 2,712E-03 0,04747733 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 2,712E-03 0,04724573 ! skeletal myofibril assembly GO:0014866 5 5 0,000 2,712E-03 0,04701639 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 5 0,000 2,712E-03 0,04678925 ! epithelial cell proliferation GO:0050673 5 5 0,000 2,712E-03 0,04656431 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 5 5 0,000 2,712E-03 0,04634151 ! regulation of retroviral genome replication GO:0045091 5 5 0,000 2,712E-03 0,04612084 ! negative regulation of survival gene product expression GO:0008634 5 5 0,000 2,712E-03 0,04590225 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 2,712E-03 0,04568573 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of defense response to virus by host GO:0050691 5 5 0,000 2,712E-03 0,04547125 ! transmembrane-ephrin receptor activity GO:0005005 5 5 0,000 2,712E-03 0,04525876 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 2,712E-03 0,04504826 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 2,712E-03 0,0448397 ! glutamate catabolic process GO:0006538 6 5 0,000 2,712E-03 0,04463307 ! positive regulation of isotype switching to IgG isotypes GO:0048304 9 5 0,000 2,712E-03 0,04442833 ! microvillus organization GO:0032528 5 5 0,000 2,712E-03 0,04422546 GO:0030033|microvillus assembly, ! tyrosine catabolic process GO:0006572 5 5 0,000 2,712E-03 0,04402443 ! L-serine biosynthetic process GO:0006564 5 5 0,000 2,712E-03 0,04382523 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 2,712E-03 0,04362782 ! pericentriolar material GO:0000242 6 5 0,000 2,712E-03 0,04343218 ! polyol biosynthetic process GO:0046173 5 5 0,000 2,712E-03 0,04323828 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 6 5 0,000 2,712E-03 0,04304611 ! platelet-derived growth factor alpha-receptor activity GO:0005018 5 5 0,000 2,712E-03 0,04285564 ! proton-transporting V-type ATPase, V0 domain GO:0033179 5 5 0,000 2,712E-03 0,04266685 ! fibroblast growth factor receptor activity GO:0005007 5 5 0,000 2,712E-03 0,04247972 ! protein-DNA loading ATPase activity GO:0033170 5 5 0,000 2,712E-03 0,04229422 GO:0003689|DNA clamp loader activity, ! insulin-like growth factor receptor activity GO:0005010 5 5 0,000 2,712E-03 0,04211033 ! response to tumor necrosis factor GO:0034612 6 5 0,000 2,712E-03 0,04192803 ! mRNA transcription GO:0009299 6 5 0,000 2,712E-03 0,04174731 ! response to ATP GO:0033198 5 5 0,000 2,712E-03 0,04156813 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 5 5 0,000 2,712E-03 0,04139049 ! adenosine receptor activity, G-protein coupled GO:0001609 5 5 0,000 2,712E-03 0,04121436 ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 2,712E-03 0,04103973 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 5 5 0,000 2,712E-03 0,04086656 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 2,712E-03 0,04069485 ! multivesicular body GO:0005771 5 5 0,000 2,712E-03 0,04052458 ! positive regulation of transporter activity GO:0032411 5 5 0,000 2,712E-03 0,04035573 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 5 5 0,000 2,712E-03 0,04018828 ! forebrain neuron development GO:0021884 6 5 0,000 2,712E-03 0,04002221 ! insulin-like growth factor I binding GO:0031994 5 5 0,000 2,712E-03 0,03985751 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 5 5 0,000 2,712E-03 0,03969416 ! demethylase activity GO:0032451 5 5 0,000 2,712E-03 0,03953214 ! peptidyl-histidine phosphorylation GO:0018106 5 5 0,000 2,712E-03 0,03937144 ! epithelial cell maturation GO:0002070 5 5 0,000 2,712E-03 0,03921205 ! nitric-oxide synthase regulator activity GO:0030235 5 5 0,000 2,712E-03 0,03905393 ! regulation of immunoglobulin secretion GO:0051023 5 5 0,000 2,712E-03 0,03889709 ! zymogen granule GO:0042588 5 5 0,000 2,712E-03 0,0387415 ! guanylate cyclase regulator activity GO:0030249 5 5 0,000 2,712E-03 0,03858715 GO:0010851|cyclase regulator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 2,712E-03 0,03843403 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! cellular glucose homeostasis GO:0001678 5 5 0,000 2,712E-03 0,03828212 ! early endosome to late endosome transport GO:0045022 5 5 0,000 2,712E-03 0,0381314 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 2,712E-03 0,03798186 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 2,712E-03 0,0378335 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! semaphorin receptor activity GO:0017154 6 5 0,000 2,712E-03 0,03768629 ! proteoglycan binding GO:0043394 9 5 0,000 2,712E-03 0,03754021 ! regulation of collagen metabolic process GO:0010712 6 5 0,000 2,712E-03 0,03739527 ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 6 5 0,000 2,712E-03 0,03725144 ! zinc ion homeostasis GO:0055069 5 5 0,000 2,712E-03 0,03710872 GO:0006882|cellular zinc ion homeostasis, ! deoxyribonucleoside metabolic process GO:0009120 6 5 0,000 2,712E-03 0,03696708 ! nucleoside monophosphate catabolic process GO:0009125 5 5 0,000 2,712E-03 0,03682652 ! activated T cell proliferation GO:0050798 6 5 0,000 2,712E-03 0,03668703 ! advanced glycation end-product receptor activity GO:0050785 5 5 0,000 2,712E-03 0,03654859 ! dynein binding GO:0045502 5 5 0,000 2,712E-03 0,03641119 ! regulation of dendrite development GO:0050773 5 5 0,000 2,712E-03 0,03627481 ! cardiac muscle cell development GO:0055013 5 5 0,000 2,712E-03 0,03613946 ! anterograde axon cargo transport GO:0008089 5 5 0,000 2,712E-03 0,03600511 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,712E-03 0,03587176 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 2,712E-03 0,03573939 GO:0003923|GPI-anchor transamidase activity, ! lymphoid progenitor cell differentiation GO:0002320 5 5 0,000 2,712E-03 0,035608 ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 2,712E-03 0,03547757 ! MutLalpha complex binding GO:0032405 6 5 0,000 2,712E-03 0,03534809 ! sphingomyelin catabolic process GO:0006685 6 5 0,000 2,712E-03 0,03521955 ! high-density lipoprotein binding GO:0008035 5 5 0,000 2,712E-03 0,03509194 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 2,712E-03 0,03496525 ! positive regulation of B cell differentiation GO:0045579 5 5 0,000 2,712E-03 0,03483948 ! regulation of acetylcholine secretion GO:0014056 5 5 0,000 2,712E-03 0,03471461 ! centromeric DNA binding GO:0019237 5 5 0,000 2,712E-03 0,03459063 ! cyclohydrolase activity GO:0019238 5 5 0,000 2,712E-03 0,03446753 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 2,712E-03 0,0343453 ! positive T cell selection GO:0043368 9 5 0,000 2,712E-03 0,03422394 ! neural tube patterning GO:0021532 5 5 0,000 2,712E-03 0,03410343 ! amylase activity GO:0016160 5 5 0,000 2,712E-03 0,03398377 ! metaphase plate congression GO:0051310 5 5 0,000 2,712E-03 0,03386495 ! regulation of sterol transport GO:0032371 5 5 0,000 2,712E-03 0,03374695 GO:0032374|regulation of cholesterol transport, ! sympathetic nervous system development GO:0048485 5 5 0,000 2,712E-03 0,03362978 ! oxygen homeostasis GO:0032364 5 5 0,000 2,712E-03 0,03351341 ! skeletal muscle regeneration GO:0043403 5 5 0,000 2,712E-03 0,03339785 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 5 5 0,000 2,712E-03 0,03328308 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 5 5 0,000 2,712E-03 0,03316909 ! SAP kinase activity GO:0016909 5 5 0,000 2,712E-03 0,03305589 ! positive regulation of pseudopodium assembly GO:0031274 5 5 0,000 2,712E-03 0,03294345 GO:0031272|regulation of pseudopodium assembly, ! phosphatidylserine binding GO:0001786 5 5 0,000 2,712E-03 0,03283178 ! alpha-mannosidase activity GO:0004559 6 5 0,000 2,712E-03 0,03272086 ! alpha-glucosidase activity GO:0004558 6 5 0,000 2,712E-03 0,03261069 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 2,712E-03 0,03250126 ! myeloid dendritic cell activation GO:0001773 5 5 0,000 2,712E-03 0,03239256 GO:0043011|myeloid dendritic cell differentiation, ! anaphase GO:0051322 5 5 0,000 2,712E-03 0,03228458 GO:0000090|mitotic anaphase, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 2,712E-03 0,03217733 ! ribonuclease H activity GO:0004523 5 5 0,000 2,712E-03 0,03207078 ! CARD domain binding GO:0050700 5 5 0,000 2,712E-03 0,03196494 ! regulation of muscle cell apoptosis GO:0010660 5 5 0,000 2,712E-03 0,03185979 ! AP-2 adaptor complex GO:0030122 5 5 0,000 2,712E-03 0,03175533 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 5 5 0,000 2,712E-03 0,03165155 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 2,712E-03 0,03154845 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 2,712E-03 0,03144602 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 2,712E-03 0,03134426 ! negative regulation of macrophage differentiation GO:0045650 5 5 0,000 2,712E-03 0,03124315 ! negative regulation of osteoclast differentiation GO:0045671 5 5 0,000 2,712E-03 0,03114269 ! ceramidase activity GO:0017040 5 5 0,000 2,712E-03 0,03104287 ! negative regulation of osteoblast differentiation GO:0045668 6 5 0,000 2,712E-03 0,03094369 ! GTP-Rho binding GO:0017049 5 5 0,000 2,712E-03 0,03084514 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 2,712E-03 0,03074722 ! chondroitin sulfotransferase activity GO:0034481 5 5 0,000 2,712E-03 0,03064992 ! positive regulation of T-helper 2 cell differentiation GO:0045630 5 5 0,000 2,712E-03 0,03055323 ! alcohol transmembrane transporter activity GO:0015665 5 5 0,000 2,712E-03 0,03045716 GO:0015166|polyol transmembrane transporter activity, ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 2,712E-03 0,03036168 ! TAP complex GO:0042825 5 5 0,000 2,712E-03 0,0302668 ! bHLH transcription factor binding GO:0043425 5 5 0,000 2,712E-03 0,03017251 ! actinin binding GO:0042805 6 5 0,000 2,712E-03 0,03007881 ! secretory granule organization GO:0033363 5 5 0,000 2,712E-03 0,02998568 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 5 5 0,000 2,712E-03 0,02989313 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 2,712E-03 0,02980116 ! striatum development GO:0021756 5 5 0,000 2,712E-03 0,02970974 ! photoreceptor inner segment GO:0001917 5 5 0,000 2,712E-03 0,02961889 ! regulation of T cell mediated cytotoxicity GO:0001914 9 5 0,000 2,712E-03 0,02952858 ! aldehyde-lyase activity GO:0016832 5 5 0,000 2,712E-03 0,02943883 ! regulation of mitochondrial depolarization GO:0051900 5 5 0,000 2,712E-03 0,02934962 ! T cell activation during immune response GO:0002286 5 5 0,000 2,712E-03 0,02926095 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 2,712E-03 0,02917282 ! 1-aminocyclopropane-1-carboxylate synthase activity GO:0016847 5 5 0,000 2,712E-03 0,02908521 ! dystroglycan complex GO:0016011 6 5 0,000 2,712E-03 0,02899813 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 5 5 0,000 2,712E-03 0,02891157 ! neural plate development GO:0001840 5 5 0,000 2,712E-03 0,02882552 ! toll-like receptor signaling pathway GO:0002224 5 5 0,000 2,712E-03 0,02873999 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 2,712E-03 0,02865496 ! phosphopantetheine binding GO:0031177 5 5 0,000 2,712E-03 0,02857043 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 2,712E-03 0,0284864 ! negative regulation of actin filament bundle formation GO:0032232 8 5 0,000 2,712E-03 0,02840286 GO:0051497|negative regulation of stress fiber formation, ! organ or tissue specific immune response GO:0002251 5 5 0,000 2,712E-03 0,02831981 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 2,712E-03 0,02823725 ! diacylglycerol metabolic process GO:0046339 5 5 0,000 2,712E-03 0,02815516 ! cytoplasmic microtubule organization GO:0031122 5 5 0,000 2,712E-03 0,02807355 ! retina homeostasis GO:0001895 5 5 0,000 2,712E-03 0,02799241 ! release of sequestered calcium ion into cytosol GO:0051209 10 5 0,000 2,712E-03 0,02791174 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 5 5 0,000 2,712E-03 0,02783154 ! regulation of growth hormone secretion GO:0060123 6 5 0,000 2,712E-03 0,02775179 ! collagen type IV GO:0005587 5 5 0,000 2,712E-03 0,0276725 ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 2,712E-03 0,02759366 ! testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045 5 5 0,000 2,712E-03 0,02751527 ! retrograde protein transport, ER to cytosol GO:0030970 5 5 0,000 2,712E-03 0,02743732 ! spindle assembly GO:0051225 5 5 0,000 2,712E-03 0,02735982 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 2,712E-03 0,02728275 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 5 5 0,000 2,712E-03 0,02720611 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 5 5 0,000 2,712E-03 0,0271299 ! protein amino acid prenylation GO:0018346 5 5 0,000 2,712E-03 0,02705412 ! stem cell division GO:0017145 5 5 0,000 2,712E-03 0,02697876 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 2,712E-03 0,02690382 ! phospholipid scrambling GO:0017121 5 5 0,000 2,712E-03 0,02682929 GO:0017128|phospholipid scramblase activity, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 5 0,000 2,712E-03 0,02675518 ! regulation of humoral immune response GO:0002920 9 5 0,000 2,712E-03 0,02668148 ! H3/H4 histone acetyltransferase activity GO:0004406 5 5 0,000 2,712E-03 0,02660817 ! regulation of interferon-alpha biosynthetic process GO:0045354 6 5 0,000 2,712E-03 0,02653528 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 2,712E-03 0,02646277 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 5 5 0,000 2,712E-03 0,02639067 GO:0030816|positive regulation of cAMP metabolic process, ! phagocytic vesicle GO:0045335 5 5 0,000 2,712E-03 0,02631896 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 2,712E-03 0,02624763 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 2,712E-03 0,02617669 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 2,712E-03 0,02610613 ! polyol transport GO:0015791 6 5 0,000 2,712E-03 0,02603596 ! cell adhesion mediated by integrin GO:0033627 6 5 0,000 2,712E-03 0,02596615 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 2,712E-03 0,02589673 ! glycerol-3-phosphate metabolic process GO:0006072 5 5 0,000 2,712E-03 0,02582767 ! platelet activating factor metabolic process GO:0046469 5 5 0,000 2,712E-03 0,02575898 ! cobalt ion transport GO:0006824 5 5 0,000 2,712E-03 0,02569065 ! response to zinc ion GO:0010043 5 5 0,000 2,712E-03 0,02562269 ! poly(U) RNA binding GO:0008266 5 5 0,000 2,712E-03 0,02555508 ! negative regulation of cell-cell adhesion GO:0022408 5 5 0,000 2,712E-03 0,02548783 ! adaptation of signaling pathway GO:0022401 5 5 0,000 2,712E-03 0,02542093 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! glucocorticoid receptor signaling pathway GO:0042921 5 5 0,000 2,712E-03 0,02535439 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 5 5 0,000 2,712E-03 0,02528819 ! sensory perception of bitter taste GO:0050913 5 5 0,000 2,712E-03 0,02522233 ! regulation of dopamine uptake GO:0051584 5 5 0,000 2,712E-03 0,02515682 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! opsonization GO:0008228 5 5 0,000 2,712E-03 0,02509165 ! protein maturation by protein folding GO:0022417 5 5 0,000 2,712E-03 0,02502681 ! neuron remodeling GO:0016322 6 5 0,000 2,712E-03 0,02496231 ! neurexin binding GO:0042043 5 5 0,000 2,712E-03 0,02489814 ! sensory perception of temperature stimulus GO:0050951 5 5 0,000 2,712E-03 0,0248343 ! regulation of potassium ion transport GO:0043266 5 5 0,000 2,712E-03 0,02477078 ! low-density lipoprotein particle GO:0034362 5 5 0,000 2,712E-03 0,02470759 ! chemoattractant activity GO:0042056 5 5 0,000 2,712E-03 0,02464472 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 6 5 0,000 2,712E-03 0,02458217 ! lipoic acid binding GO:0031405 5 5 0,000 2,712E-03 0,02451994 ! lithium ion binding GO:0031403 6 5 0,000 2,712E-03 0,02445802 ! lipoprotein particle clearance GO:0034381 5 5 0,000 2,712E-03 0,02439641 ! grooming behavior GO:0007625 5 5 0,000 2,712E-03 0,02433511 ! sequestering of actin monomers GO:0042989 5 5 0,000 2,712E-03 0,02427412 ! cobalamin binding GO:0031419 5 5 0,000 2,712E-03 0,02421344 ! retinoic acid binding GO:0001972 5 5 0,000 2,712E-03 0,02415306 ! response to axon injury GO:0048678 5 5 0,000 2,712E-03 0,02409297 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 2,712E-03 0,02403319 ! regulation of activin receptor signaling pathway GO:0032925 5 5 0,000 2,712E-03 0,0239737 ! positive regulation of neurotransmitter secretion GO:0001956 5 5 0,000 2,712E-03 0,02391451 ! mitochondrial genome maintenance GO:0000002 5 5 0,000 2,712E-03 0,0238556 ! protein-lysine 6-oxidase activity GO:0004720 6 5 0,000 2,712E-03 0,02379699 ! female pronucleus GO:0001939 5 5 0,000 2,712E-03 0,02373867 ! F-actin capping protein complex GO:0008290 5 5 0,000 2,712E-03 0,02368062 ! DNA topoisomerase activity GO:0003916 5 5 0,000 2,712E-03 0,02362287 ! poly(ADP-ribose) glycohydrolase activity GO:0004649 6 5 0,000 2,712E-03 0,02356539 ! spinal cord dorsal/ventral patterning GO:0021513 5 5 0,000 2,712E-03 0,02350819 ! dorsal spinal cord development GO:0021516 5 5 0,000 2,712E-03 0,02345127 ! ceramide catabolic process GO:0046514 5 5 0,000 2,712E-03 0,02339463 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 2,712E-03 0,02333825 ! neutrophil mediated immunity GO:0002446 5 5 0,000 2,712E-03 0,02328215 ! regulation of oligodendrocyte differentiation GO:0048713 5 5 0,000 2,712E-03 0,02322632 ! Rap GTPase activator activity GO:0046582 5 5 0,000 2,712E-03 0,02317075 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 6 5 0,000 2,712E-03 0,02311545 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 5 5 0,000 2,712E-03 0,02306042 ! positive regulation of filopodium assembly GO:0051491 5 5 0,000 2,712E-03 0,02300564 GO:0051489|regulation of filopodium assembly, ! heart trabecula formation GO:0060347 5 5 0,000 2,712E-03 0,02295113 GO:0060343|trabecula formation, ! amine oxidase activity GO:0008131 6 5 0,000 2,712E-03 0,02289687 ! neutrophil activation GO:0042119 5 5 0,000 2,712E-03 0,02284287 ! regulation of response to food GO:0032095 5 5 0,000 2,712E-03 0,02278912 ! response to food GO:0032094 5 5 0,000 2,712E-03 0,02273562 ! hedgehog receptor activity GO:0008158 5 5 0,000 2,712E-03 0,02268238 ! protein phosphatase 1 binding GO:0008157 5 5 0,000 2,712E-03 0,02262938 ! lipoprotein catabolic process GO:0042159 5 5 0,000 2,712E-03 0,02257663 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 2,712E-03 0,02252413 ! organ growth GO:0035265 7 5 0,000 2,712E-03 0,02247187 ! positive regulation of multicellular organismal metabolic process GO:0044253 6 5 0,000 2,712E-03 0,02241985 ! UDP-glucosyltransferase activity GO:0035251 5 5 0,000 2,712E-03 0,02236807 ! myosin heavy chain binding GO:0032036 5 5 0,000 2,712E-03 0,02231653 ! nucleoside salvage GO:0043174 7 5 0,000 2,712E-03 0,02226523 GO:0006166|purine ribonucleoside salvage, ! nucleobase transport GO:0015851 5 5 0,000 2,712E-03 0,02221416 ! GPI anchor binding GO:0034235 6 5 0,000 2,712E-03 0,02216333 ! thrombin receptor activity GO:0015057 5 5 0,000 2,712E-03 0,02211273 ! nucleotide-excision repair complex GO:0000109 6 5 0,000 2,712E-03 0,02206236 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 5 5 0,000 2,712E-03 0,02201222 ! dendritic shaft GO:0043198 5 5 0,000 2,712E-03 0,0219623 ! terminal button GO:0043195 8 5 0,000 2,712E-03 0,02191261 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 2,712E-03 0,02186315 GO:0016274|protein-arginine N-methyltransferase activity, ! ferrous iron binding GO:0008198 6 5 0,000 2,712E-03 0,02181391 ! eukaryotic initiation factor 4E binding GO:0008190 5 5 0,000 2,712E-03 0,02176489 ! G2/M transition checkpoint GO:0031576 5 5 0,000 2,712E-03 0,02171609 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of peptide secretion GO:0002792 6 5 0,000 2,712E-03 0,02166751 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 5 5 0,000 2,712E-03 0,02161914 ! response to UV-C GO:0010225 5 5 0,000 2,712E-03 0,02157099 ! carbonyl reductase (NADPH) activity GO:0004090 5 5 0,000 2,712E-03 0,02152306 ! regulation of alpha-beta T cell proliferation GO:0046640 9 5 0,000 2,712E-03 0,02147533 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! positive regulation of organ growth GO:0046622 5 5 0,000 2,712E-03 0,02142782 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 5 5 0,000 2,712E-03 0,02138052 ! IgE binding GO:0019863 5 5 0,000 2,712E-03 0,02133343 ! 3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 5 5 0,000 2,712E-03 0,02128654 ! monoamine transmembrane transporter activity GO:0008504 5 5 0,000 2,712E-03 0,02123986 ! response to cadmium ion GO:0046686 5 5 0,000 2,712E-03 0,02119338 ! regulation of interleukin-4 production GO:0032673 5 5 0,000 2,712E-03 0,02114711 ! hair follicle maturation GO:0048820 5 5 0,000 2,712E-03 0,02110104 ! regulation of interleukin-10 production GO:0032653 5 5 0,000 2,712E-03 0,02105516 ! ribosomal large subunit biogenesis GO:0042273 5 5 0,000 2,712E-03 0,02100949 ! base conversion or substitution editing GO:0016553 5 5 0,000 2,712E-03 0,02096402 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 2,712E-03 0,02091874 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 2,712E-03 0,02087365 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 2,712E-03 0,02082876 GO:0005218|intracellular ligand-gated calcium channel activity, ! general transcriptional repressor activity GO:0016565 5 5 0,000 2,712E-03 0,02078407 ! peroxisome fission GO:0016559 5 5 0,000 2,712E-03 0,02073956 ! alpha-tubulin binding GO:0043014 5 5 0,000 2,712E-03 0,02069525 ! mitotic recombination GO:0006312 5 5 0,000 2,712E-03 0,02065112 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,712E-03 0,02060718 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 2,712E-03 0,02056343 ! positive regulation of chemokine production GO:0032722 5 5 0,000 2,712E-03 0,02051986 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 2,712E-03 0,02047648 ! muscle cell proliferation GO:0033002 5 5 0,000 2,712E-03 0,02043328 ! membrane to membrane docking GO:0022614 5 5 0,000 2,712E-03 0,02039026 ! translation activator activity GO:0008494 5 5 0,000 2,712E-03 0,02034743 ! N-formyl peptide receptor activity GO:0004982 5 5 0,000 2,712E-03 0,02030477 ! coenzyme A biosynthetic process GO:0015937 6 5 0,000 2,712E-03 0,02026229 ! histamine receptor activity GO:0004969 5 5 0,000 2,712E-03 0,02021999 ! dopamine receptor activity GO:0004952 5 5 0,000 2,712E-03 0,02017787 ! galactosidase activity GO:0015925 5 5 0,000 2,712E-03 0,02013592 ! prostaglandin E receptor activity GO:0004957 6 5 0,000 2,712E-03 0,02009414 ! cellular response to nutrient GO:0031670 5 5 0,000 2,712E-03 0,02005254 ! basic amino acid transmembrane transporter activity GO:0015174 5 5 0,000 2,712E-03 0,02001111 ! ATP-gated cation channel activity GO:0004931 7 5 0,000 2,712E-03 0,01996985 ! cytochrome-b5 reductase activity GO:0004128 5 5 0,000 2,712E-03 0,01992876 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 2,712E-03 0,01988783 ! glycine transmembrane transporter activity GO:0015187 5 5 0,000 2,712E-03 0,01984708 ! tyrosine phosphorylation of STAT protein GO:0007260 6 5 0,000 2,712E-03 0,01980649 ! tricarboxylic acid cycle enzyme complex GO:0045239 5 5 0,000 2,712E-03 0,01976607 ! RNA polymerase I transcription factor activity GO:0003701 5 5 0,000 2,712E-03 0,01972582 ! progesterone metabolic process GO:0042448 5 5 0,000 2,712E-03 0,01968572 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 5 5 0,000 2,712E-03 0,01964579 ! disaccharide metabolic process GO:0005984 5 5 0,000 2,712E-03 0,01960602 ! 5'-3' exonuclease activity GO:0008409 5 5 0,000 2,712E-03 0,01956642 ! type II transforming growth factor beta receptor binding GO:0005114 5 5 0,000 2,712E-03 0,01952697 ! histone acetyltransferase binding GO:0035035 5 5 0,000 2,712E-03 0,01948768 ! endosome to lysosome transport GO:0008333 5 5 0,000 2,712E-03 0,01944855 ! glial cell migration GO:0008347 5 5 0,000 2,712E-03 0,01940957 ! S-acyltransferase activity GO:0016417 5 5 0,000 2,712E-03 0,01937075 ! phosphoinositide 3-kinase regulator activity GO:0035014 5 5 0,000 2,712E-03 0,01933209 ! phosphatidylinositol-4-phosphate 3-kinase activity GO:0035005 5 5 0,000 2,712E-03 0,01929358 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 2,712E-03 0,01925522 ! nucleobase transmembrane transporter activity GO:0015205 5 5 0,000 2,712E-03 0,01921701 ! asparaginase activity GO:0004067 5 5 0,000 2,712E-03 0,01917896 ! insemination GO:0007320 5 5 0,000 2,712E-03 0,01914106 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 2,712E-03 0,0191033 ! negative regulation of smooth muscle contraction GO:0045986 6 5 0,000 2,712E-03 0,0190657 ! aminoacylase activity GO:0004046 5 5 0,000 2,712E-03 0,01902824 ! receptor biosynthetic process GO:0032800 5 5 0,000 2,712E-03 0,01899093 ! penetration of zona pellucida GO:0007341 5 5 0,000 2,712E-03 0,01895377 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 6 5 0,000 2,712E-03 0,01891675 ! aldehyde reductase activity GO:0004032 5 5 0,000 2,712E-03 0,01887987 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 5 0,000 2,712E-03 0,01884314 ! unconventional myosin complex GO:0016461 5 5 0,000 2,712E-03 0,01880655 ! carnitine metabolic process GO:0009437 5 5 0,000 2,712E-03 0,01877011 GO:0006577|betaine metabolic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 6 6 0,000 3,254E-03 0,02247522 ! regulation of helicase activity GO:0051095 6 6 0,000 3,254E-03 0,02243183 ! testosterone 17-beta-dehydrogenase activity GO:0050327 6 6 0,000 3,254E-03 0,02238861 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 6 6 0,000 3,254E-03 0,02234556 ! tumor necrosis factor-mediated signaling pathway GO:0033209 6 6 0,000 3,254E-03 0,02230267 ! negative regulation of small GTPase mediated signal transduction GO:0051058 7 6 0,000 3,254E-03 0,02225994 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 7 6 0,000 3,254E-03 0,02221738 ! regulation of hormone biosynthetic process GO:0046885 6 6 0,000 3,254E-03 0,02217498 ! ephrin receptor binding GO:0046875 7 6 0,000 3,254E-03 0,02213274 ! biotin binding GO:0009374 7 6 0,000 3,254E-03 0,02209067 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 3,254E-03 0,02204875 ! insulin receptor substrate binding GO:0043560 7 6 0,000 3,254E-03 0,02200699 ! drug:hydrogen antiporter activity GO:0015307 6 6 0,000 3,254E-03 0,02196539 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 3,254E-03 0,02192394 ! carbohydrate phosphorylation GO:0046835 6 6 0,000 3,254E-03 0,02188266 ! regulation of respiratory gaseous exchange GO:0043576 6 6 0,000 3,254E-03 0,02184152 ! neuron adhesion GO:0007158 6 6 0,000 3,254E-03 0,02180054 ! establishment of tissue polarity GO:0007164 7 6 0,000 3,254E-03 0,02175972 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 6 6 0,000 3,254E-03 0,02171905 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 3,254E-03 0,02167853 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 6 0,000 3,254E-03 0,02163816 ! regulation of cardiac muscle cell proliferation GO:0060043 6 6 0,000 3,254E-03 0,02159794 ! positive regulation of receptor-mediated endocytosis GO:0048260 6 6 0,000 3,254E-03 0,02155787 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 6 6 0,000 3,254E-03 0,02151794 ! eukaryotic translation elongation factor 1 complex GO:0005853 6 6 0,000 3,254E-03 0,02147817 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 3,254E-03 0,02143854 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 6 6 0,000 3,254E-03 0,02139906 ! cytoplasmic microtubule GO:0005881 7 6 0,000 3,254E-03 0,02135972 ! Arp2/3 protein complex GO:0005885 7 6 0,000 3,254E-03 0,02132053 ! neurofilament GO:0005883 6 6 0,000 3,254E-03 0,02128148 ! glial cell fate commitment GO:0021781 6 6 0,000 3,254E-03 0,02124258 ! dynactin complex GO:0005869 6 6 0,000 3,254E-03 0,02120381 ! fibroblast growth factor receptor antagonist activity GO:0030353 6 6 0,000 3,254E-03 0,02116519 GO:0005104|fibroblast growth factor receptor binding, GO:0005152|interleukin-1 receptor antagonist activity, ! translation repressor activity GO:0030371 6 6 0,000 3,254E-03 0,02112671 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 6 6 0,000 3,254E-03 0,02108837 ! lipopolysaccharide binding GO:0001530 6 6 0,000 3,254E-03 0,02105016 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 3,254E-03 0,0210121 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 3,254E-03 0,02097417 ! negative regulation of viral genome replication GO:0045071 6 6 0,000 3,254E-03 0,02093638 ! traversing start control point of mitotic cell cycle GO:0007089 6 6 0,000 3,254E-03 0,02089872 ! protein lipoylation GO:0009249 6 6 0,000 3,254E-03 0,0208612 ! cysteine metabolic process GO:0006534 6 6 0,000 3,254E-03 0,02082382 ! regulation of isotype switching to IgG isotypes GO:0048302 10 6 0,000 3,254E-03 0,02078657 ! histidine catabolic process GO:0006548 6 6 0,000 3,254E-03 0,02074945 GO:0009077|histidine family amino acid catabolic process, ! centromeric heterochromatin GO:0005721 6 6 0,000 3,254E-03 0,02071246 ! mitochondrial respiratory chain complex assembly GO:0033108 6 6 0,000 3,254E-03 0,0206756 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 6 6 0,000 3,254E-03 0,02063888 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 6 6 0,000 3,254E-03 0,02060229 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 6 6 0,000 3,254E-03 0,02056582 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 6 0,000 3,254E-03 0,02052949 ! microtubule nucleation GO:0007020 6 6 0,000 3,254E-03 0,02049328 ! proline biosynthetic process GO:0006561 7 6 0,000 3,254E-03 0,0204572 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 3,254E-03 0,02042125 ! transforming growth factor beta receptor activity, type I GO:0005025 6 6 0,000 3,254E-03 0,02038542 ! phasic smooth muscle contraction GO:0014821 6 6 0,000 3,254E-03 0,02034972 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 3,254E-03 0,02031414 ! peptidoglycan metabolic process GO:0000270 6 6 0,000 3,254E-03 0,02027869 GO:0009253|peptidoglycan catabolic process, ! cerebral cortex neuron differentiation GO:0021895 6 6 0,000 3,254E-03 0,02024336 ! paraxial mesoderm development GO:0048339 6 6 0,000 3,254E-03 0,02020816 ! melanosome organization GO:0032438 6 6 0,000 3,254E-03 0,02017307 ! mitochondrial outer membrane translocase complex GO:0005742 6 6 0,000 3,254E-03 0,02013811 ! flotillin complex GO:0016600 6 6 0,000 3,254E-03 0,02010327 ! positive regulation of neuroblast proliferation GO:0002052 6 6 0,000 3,254E-03 0,02006855 ! positive regulation of vasoconstriction GO:0045907 6 6 0,000 3,254E-03 0,02003395 ! negative regulation of DNA recombination GO:0045910 6 6 0,000 3,254E-03 0,01999947 ! positive regulation of exocytosis GO:0045921 7 6 0,000 3,254E-03 0,0199651 ! protein tyrosine kinase activator activity GO:0030296 6 6 0,000 3,254E-03 0,01993086 ! positive regulation of fatty acid metabolic process GO:0045923 6 6 0,000 3,254E-03 0,01989673 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 3,254E-03 0,01986272 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of mitotic cell cycle GO:0045931 6 6 0,000 3,254E-03 0,01982882 ! nonhomologous end joining complex GO:0070419 6 6 0,000 3,254E-03 0,01979504 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! DNA damage response, signal transduction resulting in transcription GO:0042772 9 6 0,000 3,254E-03 0,01976138 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! vinculin binding GO:0017166 6 6 0,000 3,254E-03 0,01972783 ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 3,254E-03 0,01969439 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 3,254E-03 0,01966107 ! sodium ion homeostasis GO:0055078 6 6 0,000 3,254E-03 0,01962785 ! protein heterooligomerization GO:0051291 6 6 0,000 3,254E-03 0,01959476 ! negative regulation of gliogenesis GO:0014014 6 6 0,000 3,254E-03 0,01956177 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 8 6 0,000 3,254E-03 0,01952889 ! translation termination factor activity GO:0008079 6 6 0,000 3,254E-03 0,01949612 GO:0003747|translation release factor activity, ! centrosome duplication GO:0051298 6 6 0,000 3,254E-03 0,01946347 ! protein targeting to lysosome GO:0006622 6 6 0,000 3,254E-03 0,01943092 ! purine base biosynthetic process GO:0009113 7 6 0,000 3,254E-03 0,01939848 ! fibrinolysis GO:0042730 7 6 0,000 3,254E-03 0,01936615 ! peptidyl-asparagine modification GO:0018196 6 6 0,000 3,254E-03 0,01933393 GO:0018279|protein amino acid N-linked glycosylation via asparagine, GO:0004579|dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ! eating behavior GO:0042755 6 6 0,000 3,254E-03 0,01930181 ! B cell lineage commitment GO:0002326 6 6 0,000 3,254E-03 0,0192698 ! thiamin and derivative metabolic process GO:0042723 6 6 0,000 3,254E-03 0,0192379 ! response to exogenous dsRNA GO:0043330 6 6 0,000 3,254E-03 0,0192061 ! enucleate erythrocyte differentiation GO:0043353 6 6 0,000 3,254E-03 0,01917441 ! melanosome transport GO:0032402 6 6 0,000 3,254E-03 0,01914282 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 6 6 0,000 3,254E-03 0,01911133 GO:0014066|regulation of phosphoinositide 3-kinase cascade, ! mast cell activation GO:0045576 6 6 0,000 3,254E-03 0,01907995 ! regulation of dopamine secretion GO:0014059 6 6 0,000 3,254E-03 0,01904867 ! regulation of protein kinase B signaling cascade GO:0051896 6 6 0,000 3,254E-03 0,0190175 ! negative regulation of focal adhesion formation GO:0051895 8 6 0,000 3,254E-03 0,01898642 ! nucleoside catabolic process GO:0009164 7 6 0,000 3,254E-03 0,01895545 ! transcription initiation factor activity GO:0016986 6 6 0,000 3,254E-03 0,01892458 ! negative regulation of T cell differentiation GO:0045581 6 6 0,000 3,254E-03 0,0188938 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 3,254E-03 0,01886313 ! Schwann cell development GO:0014044 6 6 0,000 3,254E-03 0,01883256 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 6 0,000 3,254E-03 0,01880209 ! G-protein coupled photoreceptor activity GO:0008020 6 6 0,000 3,254E-03 0,01877171 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 3,254E-03 0,01874144 ! regulation of chondrocyte differentiation GO:0032330 6 6 0,000 3,254E-03 0,01871126 ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 3,254E-03 0,01868117 ! superoxide-generating NADPH oxidase activity GO:0016175 6 6 0,000 3,254E-03 0,01865119 ! nuclear envelope lumen GO:0005641 6 6 0,000 3,254E-03 0,0186213 ! RNA polymerase II transcription elongation factor activity GO:0016944 7 6 0,000 3,254E-03 0,0185915 ! regulation of meiosis GO:0040020 6 6 0,000 3,254E-03 0,0185618 GO:0051445|regulation of meiotic cell cycle, ! establishment of nucleus localization GO:0040023 8 6 0,000 3,254E-03 0,0185322 ! lipoxygenase activity GO:0016165 6 6 0,000 3,254E-03 0,01850269 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 3,254E-03 0,01847327 ! alpha DNA polymerase:primase complex GO:0005658 7 6 0,000 3,254E-03 0,01844395 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 3,254E-03 0,01841472 ! DNA replication factor C complex GO:0005663 6 6 0,000 3,254E-03 0,01838559 ! nuclear origin of replication recognition complex GO:0005664 6 6 0,000 3,254E-03 0,01835654 GO:0000808|origin recognition complex, ! DNA replication factor A complex GO:0005662 6 6 0,000 3,254E-03 0,01832759 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 3,254E-03 0,01829872 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 3,254E-03 0,01826995 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 3,254E-03 0,01824127 ! chromatin silencing complex GO:0005677 6 6 0,000 3,254E-03 0,01821268 GO:0034979|NAD-dependent protein deacetylase activity, GO:0017136|NAD-dependent histone deacetylase activity, ! U12-type spliceosomal complex GO:0005689 7 6 0,000 3,254E-03 0,01818418 ! B cell homeostasis GO:0001782 7 6 0,000 3,254E-03 0,01815577 ! regulation of respiratory burst GO:0060263 6 6 0,000 3,254E-03 0,01812744 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 10 6 0,000 3,254E-03 0,01809921 GO:0002820|negative regulation of adaptive immune response, ! immunological synapse GO:0001772 6 6 0,000 3,254E-03 0,01807106 ! MutLalpha complex GO:0032389 6 6 0,000 3,254E-03 0,018043 ! leading edge membrane GO:0031256 6 6 0,000 3,254E-03 0,01801502 ! bis(5'-adenosyl)-triphosphatase activity GO:0047710 6 6 0,000 3,254E-03 0,01798714 ! peptidyl-histidine modification GO:0018202 6 6 0,000 3,254E-03 0,01795934 ! exodeoxyribonuclease activity GO:0004529 6 6 0,000 3,254E-03 0,01793162 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! COPII vesicle coat GO:0030127 6 6 0,000 3,254E-03 0,01790399 GO:0012507|ER to Golgi transport vesicle membrane, ! peptidyl-threonine modification GO:0018210 6 6 0,000 3,254E-03 0,01787645 ! diuresis GO:0030146 6 6 0,000 3,254E-03 0,01784899 GO:0030147|natriuresis, ! definitive hemopoiesis GO:0060216 6 6 0,000 3,254E-03 0,01782161 ! glutathione biosynthetic process GO:0006750 6 6 0,000 3,254E-03 0,01779432 ! HLA-B specific inhibitory MHC class I receptor activity GO:0030109 6 6 0,000 3,254E-03 0,01776711 ! BBSome GO:0034464 6 6 0,000 3,254E-03 0,01773998 ! regulation of keratinocyte differentiation GO:0045616 6 6 0,000 3,254E-03 0,01771294 ! glycerophosphodiester phosphodiesterase activity GO:0008889 6 6 0,000 3,254E-03 0,01768598 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 3,254E-03 0,0176591 ! sodium channel regulator activity GO:0017080 6 6 0,000 3,254E-03 0,01763231 ! glycolipid catabolic process GO:0019377 6 6 0,000 3,254E-03 0,01760559 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 6 6 0,000 3,254E-03 0,01757896 ! nicotinamide nucleotide biosynthetic process GO:0019359 6 6 0,000 3,254E-03 0,0175524 ! porphyrin catabolic process GO:0006787 8 6 0,000 3,254E-03 0,01752593 GO:0033015|tetrapyrrole catabolic process, ! removal of superoxide radicals GO:0019430 6 6 0,000 3,254E-03 0,01749953 ! positive regulation of glucose import GO:0046326 7 6 0,000 3,254E-03 0,01747322 GO:0010828|positive regulation of glucose transport, ! triglyceride catabolic process GO:0019433 6 6 0,000 3,254E-03 0,01744698 ! myeloid cell homeostasis GO:0002262 6 6 0,000 3,254E-03 0,01742082 ! lamin binding GO:0005521 6 6 0,000 3,254E-03 0,01739475 ! ectodermal gut morphogenesis GO:0048567 6 6 0,000 3,254E-03 0,01736874 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 6 6 0,000 3,254E-03 0,01734282 ! pattern recognition receptor signaling pathway GO:0002221 6 6 0,000 3,254E-03 0,01731697 ! negative regulation of calcium ion transport GO:0051926 6 6 0,000 3,254E-03 0,01729121 ! peroxiredoxin activity GO:0051920 6 6 0,000 3,254E-03 0,01726551 ! complement binding GO:0001848 8 6 0,000 3,254E-03 0,0172399 ! catecholamine transport GO:0051937 6 6 0,000 3,254E-03 0,01721436 ! regulation of sensory perception GO:0051931 6 6 0,000 3,254E-03 0,01718889 GO:0051930|regulation of sensory perception of pain, ! muscle adaptation GO:0043500 6 6 0,000 3,254E-03 0,0171635 ! hemopoietic progenitor cell differentiation GO:0002244 6 6 0,000 3,254E-03 0,01713819 ! dipeptidase activity GO:0016805 6 6 0,000 3,254E-03 0,01711295 ! ether hydrolase activity GO:0016803 6 6 0,000 3,254E-03 0,01708778 ! FACIT collagen GO:0005593 6 6 0,000 3,254E-03 0,01706269 ! actin filament polymerization GO:0030041 8 6 0,000 3,254E-03 0,01703767 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 3,254E-03 0,01701272 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 6 6 0,000 3,254E-03 0,01698785 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 6 0,000 3,254E-03 0,01696305 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 3,254E-03 0,01693832 ! negative regulation of synaptic transmission GO:0050805 7 6 0,000 3,254E-03 0,01691367 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 3,254E-03 0,01688908 ! organ regeneration GO:0031100 6 6 0,000 3,254E-03 0,01686457 ! Golgi transport complex GO:0017119 6 6 0,000 3,254E-03 0,01684013 ! sheet-forming collagen GO:0030935 6 6 0,000 3,254E-03 0,01681576 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 3,254E-03 0,01679146 ! positive regulation of coagulation GO:0050820 7 6 0,000 3,254E-03 0,01676723 ! defense response to Gram-negative bacterium GO:0050829 6 6 0,000 3,254E-03 0,01674307 ! positive regulation of MHC class II biosynthetic process GO:0045348 6 6 0,000 3,254E-03 0,01671898 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 6 6 0,000 3,254E-03 0,01669496 ! thioredoxin-disulfide reductase activity GO:0004791 6 6 0,000 3,254E-03 0,016671 ! sphingomyelin phosphodiesterase activity GO:0004767 7 6 0,000 3,254E-03 0,01664712 ! regulation of cGMP metabolic process GO:0030823 6 6 0,000 3,254E-03 0,0166233 ! myoblast cell fate commitment GO:0048625 6 6 0,000 3,254E-03 0,01659956 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 3,254E-03 0,01657588 ! DNA synthesis during DNA repair GO:0000731 7 6 0,000 3,254E-03 0,01655226 ! neutral lipid biosynthetic process GO:0046460 6 6 0,000 3,254E-03 0,01652872 GO:0046463|acylglycerol biosynthetic process, ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 6 6 0,000 3,254E-03 0,01650524 ! nuclear telomere cap complex GO:0000783 6 6 0,000 3,254E-03 0,01648183 GO:0000782|telomere cap complex, ! Golgi to endosome transport GO:0006895 6 6 0,000 3,254E-03 0,01645848 ! negative regulation of JAK-STAT cascade GO:0046426 7 6 0,000 3,254E-03 0,0164352 ! sterol carrier activity GO:0005498 6 6 0,000 3,254E-03 0,01641199 ! positive regulation of cell-cell adhesion GO:0022409 6 6 0,000 3,254E-03 0,01638884 ! succinate metabolic process GO:0006105 6 6 0,000 3,254E-03 0,01636576 ! myelin sheath GO:0043209 6 6 0,000 3,254E-03 0,01634274 ! perikaryon GO:0043204 7 6 0,000 3,254E-03 0,01631979 ! oxaloacetate metabolic process GO:0006107 7 6 0,000 3,254E-03 0,0162969 ! malate metabolic process GO:0006108 6 6 0,000 3,254E-03 0,01627408 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 6 6 0,000 3,254E-03 0,01625131 ! posttranscriptional gene silencing by RNA GO:0035194 6 6 0,000 3,254E-03 0,01622862 GO:0016441|posttranscriptional gene silencing, ! mating behavior GO:0007617 6 6 0,000 3,254E-03 0,01620598 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 3,254E-03 0,01618341 ! rhythmic behavior GO:0007622 7 6 0,000 3,254E-03 0,0161609 ! copulation GO:0007620 6 6 0,000 3,254E-03 0,01613846 ! erythrocyte maturation GO:0043249 6 6 0,000 3,254E-03 0,01611607 ! equilibrioception GO:0050957 6 6 0,000 3,254E-03 0,01609375 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 3,254E-03 0,01607149 ! G-protein coupled receptor kinase activity GO:0004703 6 6 0,000 3,254E-03 0,0160493 ! chemosensory behavior GO:0007635 6 6 0,000 3,254E-03 0,01602716 ! synaptic transmission, dopaminergic GO:0001963 7 6 0,000 3,254E-03 0,01600508 ! mechanosensory behavior GO:0007638 6 6 0,000 3,254E-03 0,01598307 ! response to interferon-gamma GO:0034341 6 6 0,000 3,254E-03 0,01596111 ! spinal cord patterning GO:0021511 6 6 0,000 3,254E-03 0,01593922 ! protein geranylgeranyltransferase activity GO:0004661 6 6 0,000 3,254E-03 0,01591738 ! activation of MAPKKK activity GO:0000185 6 6 0,000 3,254E-03 0,01589561 ! nerve growth factor receptor signaling pathway GO:0048011 8 6 0,000 3,254E-03 0,01587389 ! glucosyltransferase activity GO:0046527 6 6 0,000 3,254E-03 0,01585224 ! sphingoid catabolic process GO:0046521 6 6 0,000 3,254E-03 0,01583064 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 3,254E-03 0,0158091 ! activin receptor activity GO:0017002 6 6 0,000 3,254E-03 0,01578762 ! ovulation GO:0030728 6 6 0,000 3,254E-03 0,0157662 ! dopamine binding GO:0035240 7 6 0,000 3,254E-03 0,01574484 ! hyperosmotic response GO:0006972 6 6 0,000 3,254E-03 0,01572353 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 6 6 0,000 3,254E-03 0,01570228 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 6 0,000 3,254E-03 0,01568109 ! nuclear localization sequence binding GO:0008139 6 6 0,000 3,254E-03 0,01565996 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 3,254E-03 0,01563888 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 3,254E-03 0,01561786 ! copper ion transmembrane transporter activity GO:0005375 6 6 0,000 3,254E-03 0,0155969 ! poly(A) RNA binding GO:0008143 6 6 0,000 3,254E-03 0,01557599 ! positive transcription elongation factor activity GO:0008159 6 6 0,000 3,254E-03 0,01555514 ! regulation of glycogen metabolic process GO:0070873 7 6 0,000 3,254E-03 0,01553434 GO:0032881|regulation of polysaccharide metabolic process, ! maintenance of protein location in nucleus GO:0051457 6 6 0,000 3,254E-03 0,0155136 ! intracellular pH reduction GO:0051452 6 6 0,000 3,254E-03 0,01549292 GO:0045851|pH reduction, ! purine salvage GO:0043101 8 6 0,000 3,254E-03 0,01547229 ! nucleotide-sugar transmembrane transporter activity GO:0005338 6 6 0,000 3,254E-03 0,01545172 ! neurotrophin binding GO:0043121 6 6 0,000 3,254E-03 0,0154312 ! ciliary rootlet GO:0035253 6 6 0,000 3,254E-03 0,01541073 ! neurotransmitter catabolic process GO:0042135 10 6 0,000 3,254E-03 0,01539032 ! ruffle organization GO:0031529 6 6 0,000 3,254E-03 0,01536996 ! T cell mediated immunity GO:0002456 6 6 0,000 3,254E-03 0,01534966 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 7 6 0,000 3,254E-03 0,01532941 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! carnitine transport GO:0015879 6 6 0,000 3,254E-03 0,01530921 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 3,254E-03 0,01528907 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! palmitoyl-CoA hydrolase activity GO:0016290 6 6 0,000 3,254E-03 0,01526897 ! S-methyltransferase activity GO:0008172 6 6 0,000 3,254E-03 0,01524894 ! phospholipase D activity GO:0004630 6 6 0,000 3,254E-03 0,01522895 ! rRNA modification GO:0000154 6 6 0,000 3,254E-03 0,01520902 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 3,254E-03 0,01518914 ! neuronal ion channel clustering GO:0045161 6 6 0,000 3,254E-03 0,01516931 ! response to UV-B GO:0010224 6 6 0,000 3,254E-03 0,01514953 ! interaction with symbiont GO:0051702 6 6 0,000 3,254E-03 0,0151298 ! negative regulation of insulin receptor signaling pathway GO:0046627 6 6 0,000 3,254E-03 0,01511013 ! IgG binding GO:0019864 6 6 0,000 3,254E-03 0,01509051 ! positive regulation of cytokine production during immune response GO:0002720 6 6 0,000 3,254E-03 0,01507093 ! base-excision repair, AP site formation GO:0006285 6 6 0,000 3,254E-03 0,01505141 ! benzodiazepine receptor activity GO:0008503 6 6 0,000 3,254E-03 0,01503194 ! response to copper ion GO:0046688 6 6 0,000 3,254E-03 0,01501252 ! DNA topological change GO:0006265 6 6 0,000 3,254E-03 0,01499315 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 3,254E-03 0,01497383 ! dendrite morphogenesis GO:0048813 6 6 0,000 3,254E-03 0,01495456 ! regulation of interleukin-1 beta production GO:0032651 6 6 0,000 3,254E-03 0,01493533 ! regulation of myeloid cell apoptosis GO:0033032 6 6 0,000 3,254E-03 0,01491616 ! positive regulation of tumor necrosis factor production GO:0032760 6 6 0,000 3,254E-03 0,01489704 ! nucleosome disassembly GO:0006337 6 6 0,000 3,254E-03 0,01487796 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! inositol trisphosphate 3-kinase activity GO:0008440 6 6 0,000 3,254E-03 0,01485894 ! regulation of mast cell activation GO:0033003 6 6 0,000 3,254E-03 0,01483996 ! guanylyltransferase activity GO:0070568 6 6 0,000 3,254E-03 0,01482103 ! receptor internalization GO:0031623 7 6 0,000 3,254E-03 0,01480215 ! neuropeptide Y receptor activity GO:0004983 6 6 0,000 3,254E-03 0,01478332 ! ATP-dependent peptidase activity GO:0004176 6 6 0,000 3,254E-03 0,01476454 ! serine-type carboxypeptidase activity GO:0004185 6 6 0,000 3,254E-03 0,0147458 GO:0070008|serine-type exopeptidase activity, ! protein deubiquitination GO:0016579 6 6 0,000 3,254E-03 0,01472711 ! negative regulation of neuroblast proliferation GO:0007406 6 6 0,000 3,254E-03 0,01470847 ! NuRD complex GO:0016581 6 6 0,000 3,254E-03 0,01468987 ! nucleosome positioning GO:0016584 6 6 0,000 3,254E-03 0,01467133 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 3,254E-03 0,01465282 ! alpha-adrenergic receptor activity GO:0004936 8 6 0,000 3,254E-03 0,01463437 ! glycine binding GO:0016594 8 6 0,000 3,254E-03 0,01461596 ! costamere GO:0043034 7 6 0,000 3,254E-03 0,0145976 ! A band GO:0031672 6 6 0,000 3,254E-03 0,01457928 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 3,254E-03 0,01456101 ! dopamine biosynthetic process GO:0042416 7 6 0,000 3,254E-03 0,01454279 ! procollagen-proline dioxygenase activity GO:0019798 6 6 0,000 3,254E-03 0,01452461 ! negative regulation of axon extension GO:0030517 6 6 0,000 3,254E-03 0,01450648 ! actin monomer binding GO:0003785 6 6 0,000 3,254E-03 0,01448839 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 3,254E-03 0,01447035 ! lysozyme activity GO:0003796 6 6 0,000 3,254E-03 0,01445235 ! regulation of Rac protein signal transduction GO:0035020 6 6 0,000 3,254E-03 0,0144344 ! ATP catabolic process GO:0006200 6 6 0,000 3,254E-03 0,01441649 ! determination of adult lifespan GO:0008340 6 6 0,000 3,254E-03 0,01439862 ! somatic stem cell maintenance GO:0035019 6 6 0,000 3,254E-03 0,0143808 ! negative regulation of organic acid transport GO:0032891 6 6 0,000 3,254E-03 0,01436303 ! establishment of apical/basal cell polarity GO:0035089 6 6 0,000 3,254E-03 0,0143453 ! calcium-dependent phospholipase A2 activity GO:0047498 6 6 0,000 3,254E-03 0,01432761 ! O-acetyltransferase activity GO:0016413 6 6 0,000 3,254E-03 0,01430996 ! CoA-ligase activity GO:0016405 6 6 0,000 3,254E-03 0,01429236 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 3,254E-03 0,0142748 ! IkappaB kinase complex GO:0008385 6 6 0,000 3,254E-03 0,01425729 ! pyrimidine nucleotide catabolic process GO:0006244 6 6 0,000 3,254E-03 0,01423982 ! store-operated calcium channel activity GO:0015279 6 6 0,000 3,254E-03 0,01422239 ! aminomethyltransferase activity GO:0004047 6 6 0,000 3,254E-03 0,014205 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 6 6 0,000 3,254E-03 0,01418766 ! alkaline phosphatase activity GO:0004035 6 6 0,000 3,254E-03 0,01417035 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 6 6 0,000 3,254E-03 0,01415309 ! oligosaccharide biosynthetic process GO:0009312 7 7 0,000 3,795E-03 0,01648794 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 3,795E-03 0,0164679 ! sleep GO:0030431 7 7 0,000 3,795E-03 0,01644792 ! synaptonemal complex assembly GO:0007130 7 7 0,000 3,795E-03 0,01642798 GO:0070193|synaptonemal complex organization, ! forebrain regionalization GO:0021871 7 7 0,000 3,795E-03 0,01640809 ! cell proliferation in forebrain GO:0021846 7 7 0,000 3,795E-03 0,01638825 ! proteasome regulatory particle GO:0005838 8 7 0,000 3,795E-03 0,01636846 ! meiotic prophase I GO:0007128 7 7 0,000 3,795E-03 0,01634872 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 7 0,000 3,795E-03 0,01632902 ! SMAD protein nuclear translocation GO:0007184 8 7 0,000 3,795E-03 0,01630937 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 7 7 0,000 3,795E-03 0,01628977 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 3,795E-03 0,01627021 ! diphosphotransferase activity GO:0016778 8 7 0,000 3,795E-03 0,0162507 ! actin-myosin filament sliding GO:0033275 7 7 0,000 3,795E-03 0,01623124 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! signal peptide processing GO:0006465 7 7 0,000 3,795E-03 0,01621182 ! glycine hydroxymethyltransferase activity GO:0004372 8 7 0,000 3,795E-03 0,01619246 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 3,795E-03 0,01617313 ! macrophage chemotaxis GO:0048246 7 7 0,000 3,795E-03 0,01615386 ! cerebral cortex cell migration GO:0021795 7 7 0,000 3,795E-03 0,01613462 ! tachykinin receptor signaling pathway GO:0007217 7 7 0,000 3,795E-03 0,01611544 ! membrane hyperpolarization GO:0060081 7 7 0,000 3,795E-03 0,0160963 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 3,795E-03 0,01607721 ! DNA replication origin binding GO:0003688 7 7 0,000 3,795E-03 0,01605816 ! ATPase binding GO:0051117 7 7 0,000 3,795E-03 0,01603915 ! positive regulation of glycolysis GO:0045821 7 7 0,000 3,795E-03 0,01602019 ! positive regulation of isotype switching GO:0045830 11 7 0,000 3,795E-03 0,01600128 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 8 7 0,000 3,795E-03 0,01598241 ! ribonucleoside triphosphate catabolic process GO:0009203 7 7 0,000 3,795E-03 0,01596359 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! protein-cofactor linkage GO:0018065 7 7 0,000 3,795E-03 0,01594481 ! positive regulation of chemokine biosynthetic process GO:0045080 7 7 0,000 3,795E-03 0,01592607 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 7 7 0,000 3,795E-03 0,01590738 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! thymic T cell selection GO:0045061 11 7 0,000 3,795E-03 0,01588873 ! structural constituent of tooth enamel GO:0030345 7 7 0,000 3,795E-03 0,01587012 ! transepithelial chloride transport GO:0030321 7 7 0,000 3,795E-03 0,01585156 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 3,795E-03 0,01583304 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 3,795E-03 0,01581457 ! glycine catabolic process GO:0006546 7 7 0,000 3,795E-03 0,01579614 GO:0009071|serine family amino acid catabolic process, ! deoxyribonucleotide biosynthetic process GO:0009263 8 7 0,000 3,795E-03 0,01577775 ! cytoskeletal anchoring at plasma membrane GO:0007016 8 7 0,000 3,795E-03 0,0157594 ! response to pH GO:0009268 7 7 0,000 3,795E-03 0,0157411 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 3,795E-03 0,01572284 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! polyamine biosynthetic process GO:0006596 7 7 0,000 3,795E-03 0,01570462 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 7 7 0,000 3,795E-03 0,01568644 ! endosome organization GO:0007032 7 7 0,000 3,795E-03 0,01566831 ! thyroid hormone generation GO:0006590 7 7 0,000 3,795E-03 0,01565021 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 3,795E-03 0,01563216 GO:0021940|positive regulation of granule cell precursor proliferation, ! reverse cholesterol transport GO:0043691 7 7 0,000 3,795E-03 0,01561415 ! tumor necrosis factor receptor activity GO:0005031 7 7 0,000 3,795E-03 0,01559619 ! indolalkylamine metabolic process GO:0006586 7 7 0,000 3,795E-03 0,01557826 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! proton-transporting V-type ATPase, V1 domain GO:0033180 7 7 0,000 3,795E-03 0,01556037 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 3,795E-03 0,01554253 ! retinoid X receptor binding GO:0046965 7 7 0,000 3,795E-03 0,01552473 ! central nervous system neuron axonogenesis GO:0021955 7 7 0,000 3,795E-03 0,01550696 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 3,795E-03 0,01548924 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! platelet-derived growth factor receptor activity GO:0005017 7 7 0,000 3,795E-03 0,01547156 ! urea metabolic process GO:0019627 7 7 0,000 3,795E-03 0,01545392 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! retinoic acid receptor signaling pathway GO:0048384 7 7 0,000 3,795E-03 0,01543632 ! regulation of type I interferon production GO:0032479 8 7 0,000 3,795E-03 0,01541875 ! peroxisomal matrix GO:0005782 7 7 0,000 3,795E-03 0,01540123 GO:0031907|microbody lumen, ! methyltransferase complex GO:0034708 7 7 0,000 3,795E-03 0,01538375 GO:0035097|histone methyltransferase complex, ! response to dietary excess GO:0002021 7 7 0,000 3,795E-03 0,01536631 ! p53 binding GO:0002039 7 7 0,000 3,795E-03 0,01534891 ! osteoblast development GO:0002076 8 7 0,000 3,795E-03 0,01533154 ! positive regulation of nitric-oxide synthase activity GO:0051000 7 7 0,000 3,795E-03 0,01531422 ! lipid phosphatase activity GO:0042577 7 7 0,000 3,795E-03 0,01529694 ! male sex determination GO:0030238 7 7 0,000 3,795E-03 0,01527969 ! clathrin binding GO:0030276 8 7 0,000 3,795E-03 0,01526248 ! determination of anterior/posterior axis, embryo GO:0008595 7 7 0,000 3,795E-03 0,01524531 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 7 7 0,000 3,795E-03 0,01522819 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 3,795E-03 0,01521109 GO:0030204|chondroitin sulfate metabolic process, ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 3,795E-03 0,01519404 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 3,795E-03 0,01517703 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 3,795E-03 0,01516005 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 3,795E-03 0,01514311 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 8 7 0,000 3,795E-03 0,01512621 ! hyaluronan metabolic process GO:0030212 8 7 0,000 3,795E-03 0,01510935 ! protein retention in ER lumen GO:0006621 7 7 0,000 3,795E-03 0,01509252 ! cardiac muscle cell differentiation GO:0055007 7 7 0,000 3,795E-03 0,01507573 ! peptidyl-arginine modification GO:0018195 7 7 0,000 3,795E-03 0,01505898 ! regulation of circadian rhythm GO:0042752 7 7 0,000 3,795E-03 0,01504227 ! Hsp90 protein binding GO:0051879 7 7 0,000 3,795E-03 0,01502559 ! MutSalpha complex binding GO:0032407 8 7 0,000 3,795E-03 0,01500895 ! regulation of fat cell differentiation GO:0045598 7 7 0,000 3,795E-03 0,01499235 ! establishment of melanosome localization GO:0032401 7 7 0,000 3,795E-03 0,01497578 ! gas homeostasis GO:0033483 7 7 0,000 3,795E-03 0,01495925 ! cranial nerve morphogenesis GO:0021602 7 7 0,000 3,795E-03 0,01494276 ! subpallium development GO:0021544 7 7 0,000 3,795E-03 0,0149263 ! laminin-1 complex GO:0005606 7 7 0,000 3,795E-03 0,01490988 GO:0043256|laminin complex, ! molybdopterin cofactor biosynthetic process GO:0032324 7 7 0,000 3,795E-03 0,0148935 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 8 7 0,000 3,795E-03 0,01487715 ! eye photoreceptor cell differentiation GO:0001754 10 7 0,000 3,795E-03 0,01486084 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 7 7 0,000 3,795E-03 0,01484456 ! positive regulation of immunoglobulin mediated immune response GO:0002891 11 7 0,000 3,795E-03 0,01482832 GO:0002714|positive regulation of B cell mediated immunity, ! protein sumoylation GO:0016925 7 7 0,000 3,795E-03 0,01481211 ! establishment of chromosome localization GO:0051303 7 7 0,000 3,795E-03 0,01479594 GO:0050000|chromosome localization, ! regulation of lipid transport GO:0032368 7 7 0,000 3,795E-03 0,01477981 ! regulation of cell division GO:0051302 7 7 0,000 3,795E-03 0,01476371 ! chromatin assembly complex GO:0005678 7 7 0,000 3,795E-03 0,01474764 ! sex chromatin GO:0001739 7 7 0,000 3,795E-03 0,01473161 GO:0000803|sex chromosome, ! oligosaccharyl transferase activity GO:0004576 7 7 0,000 3,795E-03 0,01471562 ! chitinase activity GO:0004568 7 7 0,000 3,795E-03 0,01469966 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 7 7 0,000 3,795E-03 0,01468373 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 7 7 0,000 3,795E-03 0,01466784 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 10 7 0,000 3,795E-03 0,01465198 ! inhibitory MHC class I receptor activity GO:0032396 7 7 0,000 3,795E-03 0,01463616 GO:0030110|HLA-C specific inhibitory MHC class I receptor activity, ! ER to Golgi transport vesicle GO:0030134 7 7 0,000 3,795E-03 0,01462037 ! molybdenum ion binding GO:0030151 7 7 0,000 3,795E-03 0,01460462 ! centriolar satellite GO:0034451 8 7 0,000 3,795E-03 0,0145889 ! positive regulation of epidermis development GO:0045684 7 7 0,000 3,795E-03 0,01457321 ! proteasome regulator activity GO:0010860 7 7 0,000 3,795E-03 0,01455756 ! antibiotic transport GO:0042891 7 7 0,000 3,795E-03 0,01454194 ! negative regulation of transmission of nerve impulse GO:0051970 8 7 0,000 3,795E-03 0,01452635 ! regulation of synaptic transmission, glutamatergic GO:0051966 7 7 0,000 3,795E-03 0,0145108 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 3,795E-03 0,01449528 ! aspartate family amino acid catabolic process GO:0009068 7 7 0,000 3,795E-03 0,01447979 ! Wnt receptor activity GO:0042813 7 7 0,000 3,795E-03 0,01446434 ! regulation of protein homodimerization activity GO:0043496 7 7 0,000 3,795E-03 0,01444892 ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 7 7 0,000 3,795E-03 0,01443353 ! positive regulation of viral reproduction GO:0048524 7 7 0,000 3,795E-03 0,01441818 ! negative regulation of viral reproduction GO:0048525 7 7 0,000 3,795E-03 0,01440285 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 9 7 0,000 3,795E-03 0,01438756 ! blastocyst growth GO:0001832 7 7 0,000 3,795E-03 0,01437231 ! pigment granule transport GO:0051904 7 7 0,000 3,795E-03 0,01435708 ! lymphocyte activation during immune response GO:0002285 7 7 0,000 3,795E-03 0,01434189 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 3,795E-03 0,01432673 ! negative regulation of fibrinolysis GO:0051918 7 7 0,000 3,795E-03 0,0143116 ! negative regulation of telomere maintenance GO:0032205 7 7 0,000 3,795E-03 0,0142965 ! cerebellar cortex formation GO:0021697 8 7 0,000 3,795E-03 0,01428144 ! activation of innate immune response GO:0002218 7 7 0,000 3,795E-03 0,01426641 GO:0002758|innate immune response-activating signal transduction, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 7 7 0,000 3,795E-03 0,0142514 ! natural killer cell mediated immunity GO:0002228 7 7 0,000 3,795E-03 0,01423643 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of synaptic transmission, dopaminergic GO:0032225 7 7 0,000 3,795E-03 0,0142215 ! regulation of synaptic transmission, GABAergic GO:0032228 7 7 0,000 3,795E-03 0,01420659 ! flavin-containing monooxygenase activity GO:0004499 7 7 0,000 3,795E-03 0,01419171 ! regulation of muscle adaptation GO:0043502 7 7 0,000 3,795E-03 0,01417687 ! sequestering of metal ion GO:0051238 7 7 0,000 3,795E-03 0,01416205 ! regulation of T cell receptor signaling pathway GO:0050856 8 7 0,000 3,795E-03 0,01414727 ! membrane attack complex GO:0005579 7 7 0,000 3,795E-03 0,01413252 ! fibrinogen complex GO:0005577 7 7 0,000 3,795E-03 0,0141178 ! septin complex GO:0031105 9 7 0,000 3,795E-03 0,01410311 GO:0032156|septin cytoskeleton, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 7 7 0,000 3,795E-03 0,01408845 ! positive regulation of microtubule polymerization GO:0031116 7 7 0,000 3,795E-03 0,01407382 ! cellular anion homeostasis GO:0030002 7 7 0,000 3,795E-03 0,01405922 GO:0055081|anion homeostasis, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 7 7 0,000 3,795E-03 0,01404465 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! behavioral response to cocaine GO:0048148 9 7 0,000 3,795E-03 0,01403011 ! autophagic vacuole formation GO:0000045 8 7 0,000 3,795E-03 0,0140156 ! negative regulation of smooth muscle cell proliferation GO:0048662 7 7 0,000 3,795E-03 0,01400112 ! regulation of lipid catabolic process GO:0050994 7 7 0,000 3,795E-03 0,01398667 ! activin binding GO:0048185 7 7 0,000 3,795E-03 0,01397225 ! syncytium formation by plasma membrane fusion GO:0000768 7 7 0,000 3,795E-03 0,01395786 GO:0007520|myoblast fusion, ! nucleotide-excision repair, DNA incision GO:0033683 7 7 0,000 3,795E-03 0,0139435 ! oligosaccharyltransferase complex GO:0008250 7 7 0,000 3,795E-03 0,01392917 ! phototransduction, visible light GO:0007603 7 7 0,000 3,795E-03 0,01391487 ! positive regulation of neurotransmitter transport GO:0051590 7 7 0,000 3,795E-03 0,0139006 ! lipoprotein transport GO:0042953 7 7 0,000 3,795E-03 0,01388636 ! cell division site part GO:0032155 7 7 0,000 3,795E-03 0,01387214 GO:0032153|cell division site, ! laminin binding GO:0043236 9 7 0,000 3,795E-03 0,01385796 ! detection of mechanical stimulus involved in sensory perception GO:0050974 7 7 0,000 3,795E-03 0,0138438 ! phospholipid efflux GO:0033700 7 7 0,000 3,795E-03 0,01382968 ! DNA insertion or deletion binding GO:0032135 7 7 0,000 3,795E-03 0,01381558 GO:0032138|single base insertion or deletion binding, ! glucocorticoid metabolic process GO:0008211 7 7 0,000 3,795E-03 0,01380151 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 7 7 0,000 3,795E-03 0,01378747 ! poly-purine tract binding GO:0070717 7 7 0,000 3,795E-03 0,01377346 ! T-helper 1 type immune response GO:0042088 7 7 0,000 3,795E-03 0,01375948 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 3,795E-03 0,01374552 GO:0032107|regulation of response to nutrient levels, ! amyloid precursor protein catabolic process GO:0042987 7 7 0,000 3,795E-03 0,0137316 ! leukocyte degranulation GO:0043299 7 7 0,000 3,795E-03 0,0137177 ! sodium:phosphate symporter activity GO:0005436 7 7 0,000 3,795E-03 0,01370383 ! bile acid and bile salt transport GO:0015721 7 7 0,000 3,795E-03 0,01368998 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 3,795E-03 0,01367617 ! glycerol ether biosynthetic process GO:0046504 7 7 0,000 3,795E-03 0,01366238 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 3,795E-03 0,01364863 GO:0046513|ceramide biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 3,795E-03 0,01363489 ! pigment granule organization GO:0048753 7 7 0,000 3,795E-03 0,01362119 ! eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 7 7 0,000 3,795E-03 0,01360751 ! regulation of interleukin-8 biosynthetic process GO:0045414 8 7 0,000 3,795E-03 0,01359387 ! regulation of pigmentation during development GO:0048070 10 7 0,000 3,795E-03 0,01358025 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 7 7 0,000 3,795E-03 0,01356665 ! macrophage activation GO:0042116 7 7 0,000 3,795E-03 0,01355308 ! positive regulation of activated T cell proliferation GO:0042104 7 7 0,000 3,795E-03 0,01353955 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 7 7 0,000 3,795E-03 0,01352603 ! galactose metabolic process GO:0006012 7 7 0,000 3,795E-03 0,01351255 ! vesicle fusion GO:0006906 7 7 0,000 3,795E-03 0,01349909 ! positive regulation of insulin secretion GO:0032024 7 7 0,000 3,795E-03 0,01348566 ! glycerol ether catabolic process GO:0044269 7 7 0,000 3,795E-03 0,01347225 GO:0046464|acylglycerol catabolic process, ! virus-infected cell apoptosis GO:0006926 7 7 0,000 3,795E-03 0,01345887 ! NuA4 histone acetyltransferase complex GO:0035267 8 7 0,000 3,795E-03 0,01344552 ! nucleoside transmembrane transporter activity GO:0005337 7 7 0,000 3,795E-03 0,0134322 GO:0015858|nucleoside transport, ! regulation of vascular permeability GO:0043114 7 7 0,000 3,795E-03 0,0134189 ! regulation of multicellular organismal metabolic process GO:0044246 8 7 0,000 3,795E-03 0,01340562 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 3,795E-03 0,01339238 ! peptidyl-proline dioxygenase activity GO:0031543 7 7 0,000 3,795E-03 0,01337916 ! inclusion body GO:0016234 7 7 0,000 3,795E-03 0,01336596 ! parturition GO:0007567 7 7 0,000 3,795E-03 0,01335279 ! tRNA methyltransferase activity GO:0008175 7 7 0,000 3,795E-03 0,01333965 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 7 7 0,000 3,795E-03 0,01332653 ! intercalated disc GO:0014704 8 7 0,000 3,795E-03 0,01331344 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 3,795E-03 0,01330038 ! neural nucleus development GO:0048857 7 7 0,000 3,795E-03 0,01328734 ! intermediate filament organization GO:0045109 8 7 0,000 3,795E-03 0,01327432 ! skeletal muscle contraction GO:0003009 7 7 0,000 3,795E-03 0,01326134 ! response to antibiotic GO:0046677 7 7 0,000 3,795E-03 0,01324837 ! positive regulation of production of molecular mediator of immune response GO:0002702 7 7 0,000 3,795E-03 0,01323543 ! hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 7 7 0,000 3,795E-03 0,01322252 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 7 7 0,000 3,795E-03 0,01320963 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 3,795E-03 0,01319677 ! regulation of interleukin-1 production GO:0032652 7 7 0,000 3,795E-03 0,01318393 ! phosphofructokinase activity GO:0008443 7 7 0,000 3,795E-03 0,01317112 ! postreplication repair GO:0006301 7 7 0,000 3,795E-03 0,01315833 ! gap junction channel activity GO:0005243 7 7 0,000 3,795E-03 0,01314557 ! transcription from RNA polymerase I promoter GO:0006360 7 7 0,000 3,795E-03 0,01313283 ! mitochondrion morphogenesis GO:0070584 8 7 0,000 3,795E-03 0,01312012 ! transcription termination GO:0006353 8 7 0,000 3,795E-03 0,01310743 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 7 7 0,000 3,795E-03 0,01309477 ! tetracycline transporter activity GO:0008493 7 7 0,000 3,795E-03 0,01308213 GO:0042895|antibiotic transporter activity, ! cytidylyltransferase activity GO:0070567 7 7 0,000 3,795E-03 0,01306951 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 3,795E-03 0,01305692 ! melanocortin receptor activity GO:0004977 7 7 0,000 3,795E-03 0,01304436 ! coenzyme A metabolic process GO:0015936 8 7 0,000 3,795E-03 0,01303181 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 7 0,000 3,795E-03 0,01301929 ! regulation of macrophage activation GO:0043030 7 7 0,000 3,795E-03 0,0130068 ! cytidine deaminase activity GO:0004126 7 7 0,000 3,795E-03 0,01299433 ! inositol trisphosphate kinase activity GO:0051766 7 7 0,000 3,795E-03 0,01298188 ! apical protein localization GO:0045176 7 7 0,000 3,795E-03 0,01296946 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 3,795E-03 0,01295706 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 3,795E-03 0,01294468 ! virion binding GO:0046790 10 7 0,000 3,795E-03 0,01293233 ! nonprotein amino acid metabolic process GO:0019794 7 7 0,000 3,795E-03 0,01292 ! protein prenyltransferase activity GO:0008318 7 7 0,000 3,795E-03 0,0129077 ! protein modification by small protein removal GO:0070646 7 7 0,000 3,795E-03 0,01289542 ! adult feeding behavior GO:0008343 7 7 0,000 3,795E-03 0,01288316 ! CoA carboxylase activity GO:0016421 7 7 0,000 3,795E-03 0,01287093 ! microtubule basal body GO:0005932 7 7 0,000 3,795E-03 0,01285871 ! positive regulation of NF-kappaB import into nucleus GO:0042346 7 7 0,000 3,795E-03 0,01284653 ! embryonic heart tube development GO:0035050 7 7 0,000 3,795E-03 0,01283436 ! kainate selective glutamate receptor activity GO:0015277 7 7 0,000 3,795E-03 0,01282222 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 3,795E-03 0,0128101 ! positive regulation of smooth muscle contraction GO:0045987 7 7 0,000 3,795E-03 0,012798 ! rRNA transcription GO:0009303 8 8 0,000 4,336E-03 0,01460902 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 8 8 0,000 4,336E-03 0,01459525 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 4,336E-03 0,01458151 ! sodium:hydrogen antiporter activity GO:0015385 8 8 0,000 4,336E-03 0,01456779 GO:0005451|monovalent cation:hydrogen antiporter activity, ! negative regulation of lipid biosynthetic process GO:0051055 9 8 0,000 4,336E-03 0,0145541 ! cation:chloride symporter activity GO:0015377 9 8 0,000 4,336E-03 0,01454043 ! positive regulation of small GTPase mediated signal transduction GO:0051057 8 8 0,000 4,336E-03 0,01452679 GO:0046579|positive regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 8 0,000 4,336E-03 0,01451318 ! male meiosis GO:0007140 8 8 0,000 4,336E-03 0,01449959 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8 8 0,000 4,336E-03 0,01448603 ! N-glycan processing GO:0006491 8 8 0,000 4,336E-03 0,01447249 ! regulation of smooth muscle cell migration GO:0014910 9 8 0,000 4,336E-03 0,01445897 ! protein self-association GO:0043621 8 8 0,000 4,336E-03 0,01444549 ! RNA methylation GO:0001510 8 8 0,000 4,336E-03 0,01443202 ! prostaglandin biosynthetic process GO:0001516 9 8 0,000 4,336E-03 0,01441859 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 8 8 0,000 4,336E-03 0,01440517 ! regulation of activated T cell proliferation GO:0046006 8 8 0,000 4,336E-03 0,01439179 ! hexokinase activity GO:0004396 8 8 0,000 4,336E-03 0,01437842 ! neurofilament cytoskeleton GO:0060053 8 8 0,000 4,336E-03 0,01436508 ! guanylate cyclase activity GO:0004383 8 8 0,000 4,336E-03 0,01435177 ! integral to mitochondrial membrane GO:0032592 8 8 0,000 4,336E-03 0,01433848 ! troponin complex GO:0005861 9 8 0,000 4,336E-03 0,01432522 ! smoothened signaling pathway GO:0007224 8 8 0,000 4,336E-03 0,01431198 ! negative regulation of muscle cell differentiation GO:0051148 8 8 0,000 4,336E-03 0,01429876 ! ganglioside metabolic process GO:0001573 8 8 0,000 4,336E-03 0,01428557 ! reflex GO:0060004 11 8 0,000 4,336E-03 0,01427241 ! small protein activating enzyme activity GO:0008641 10 8 0,000 4,336E-03 0,01425926 ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 4,336E-03 0,01424615 ! hemoglobin metabolic process GO:0020027 8 8 0,000 4,336E-03 0,01423305 ! protein targeting to ER GO:0045047 9 8 0,000 4,336E-03 0,01421998 ! positive regulation of survival gene product expression GO:0045885 8 8 0,000 4,336E-03 0,01420694 ! arginine catabolic process GO:0006527 8 8 0,000 4,336E-03 0,01419391 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 4,336E-03 0,01418092 ! malate dehydrogenase activity GO:0016615 8 8 0,000 4,336E-03 0,01416794 ! inner mitochondrial membrane organization GO:0007007 9 8 0,000 4,336E-03 0,01415499 ! telomere maintenance via telomerase GO:0007004 8 8 0,000 4,336E-03 0,01414206 GO:0010833|telomere maintenance via telomere lengthening, ! DNA secondary structure binding GO:0000217 8 8 0,000 4,336E-03 0,01412916 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 9 8 0,000 4,336E-03 0,01411628 ! proline metabolic process GO:0006560 9 8 0,000 4,336E-03 0,01410343 ! melanosome membrane GO:0033162 10 8 0,000 4,336E-03 0,01409059 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 4,336E-03 0,01407778 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 4,336E-03 0,014065 ! melanin metabolic process GO:0006582 9 8 0,000 4,336E-03 0,01405223 ! death receptor activity GO:0005035 8 8 0,000 4,336E-03 0,01403949 ! Golgi lumen GO:0005796 8 8 0,000 4,336E-03 0,01402678 ! smooth endoplasmic reticulum GO:0005790 9 8 0,000 4,336E-03 0,01401408 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 4,336E-03 0,01400141 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 9 8 0,000 4,336E-03 0,01398876 GO:0048500|signal recognition particle, ! Golgi cisterna GO:0031985 9 8 0,000 4,336E-03 0,01397614 ! positive regulation of mesenchymal cell proliferation GO:0002053 8 8 0,000 4,336E-03 0,01396354 ! Rac protein signal transduction GO:0016601 8 8 0,000 4,336E-03 0,01395096 ! positive regulation of calcium ion transport into cytosol GO:0010524 11 8 0,000 4,336E-03 0,0139384 ! lens development in camera-type eye GO:0002088 8 8 0,000 4,336E-03 0,01392586 ! positive regulation of vasodilation GO:0045909 8 8 0,000 4,336E-03 0,01391335 ! intestinal cholesterol absorption GO:0030299 8 8 0,000 4,336E-03 0,01390086 ! negative regulation of muscle contraction GO:0045932 9 8 0,000 4,336E-03 0,0138884 ! positive regulation vascular endothelial growth factor production GO:0010575 8 8 0,000 4,336E-03 0,01387595 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 8 8 0,000 4,336E-03 0,01386353 ! Schwann cell differentiation GO:0014037 8 8 0,000 4,336E-03 0,01385113 ! sodium:dicarboxylate symporter activity GO:0017153 8 8 0,000 4,336E-03 0,01383875 ! axon guidance receptor activity GO:0008046 8 8 0,000 4,336E-03 0,01382639 ! protein targeting to vacuole GO:0006623 8 8 0,000 4,336E-03 0,01381406 ! response to tropane GO:0014073 10 8 0,000 4,336E-03 0,01380175 GO:0042220|response to cocaine, ! purine nucleoside triphosphate catabolic process GO:0009146 8 8 0,000 4,336E-03 0,01378946 ! melanosome localization GO:0032400 8 8 0,000 4,336E-03 0,01377719 ! response to amine stimulus GO:0014075 10 8 0,000 4,336E-03 0,01376494 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 8 8 0,000 4,336E-03 0,01375272 ! sphingomyelin metabolic process GO:0006684 9 8 0,000 4,336E-03 0,01374052 ! regulation of mitochondrial membrane potential GO:0051881 8 8 0,000 4,336E-03 0,01372833 ! synaptic vesicle endocytosis GO:0048488 8 8 0,000 4,336E-03 0,01371617 ! holo TFIIH complex GO:0005675 8 8 0,000 4,336E-03 0,01370404 ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 4,336E-03 0,01369192 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 8 0,000 4,336E-03 0,01367982 ! negative regulation of cytokine secretion GO:0050710 8 8 0,000 4,336E-03 0,01366775 ! regulation of myoblast differentiation GO:0045661 8 8 0,000 4,336E-03 0,0136557 ! vitamin transporter activity GO:0051183 8 8 0,000 4,336E-03 0,01364367 ! positive regulation of erythrocyte differentiation GO:0045648 8 8 0,000 4,336E-03 0,01363166 ! neuromuscular process controlling posture GO:0050884 8 8 0,000 4,336E-03 0,01361967 ! heparan sulfate sulfotransferase activity GO:0034483 8 8 0,000 4,336E-03 0,0136077 ! regulation of epidermal cell differentiation GO:0045604 8 8 0,000 4,336E-03 0,01359575 ! regulation of T-helper 2 cell differentiation GO:0045628 8 8 0,000 4,336E-03 0,01358383 ! positive regulation of T-helper cell differentiation GO:0045624 8 8 0,000 4,336E-03 0,01357192 ! branched chain family amino acid catabolic process GO:0009083 8 8 0,000 4,336E-03 0,01356004 ! regulation of synaptogenesis GO:0051963 8 8 0,000 4,336E-03 0,01354817 ! oocyte differentiation GO:0009994 8 8 0,000 4,336E-03 0,01353633 GO:0048599|oocyte development, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 8 8 0,000 4,336E-03 0,01352451 GO:0003756|protein disulfide isomerase activity, ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 4,336E-03 0,01351271 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 8 0,000 4,336E-03 0,01350093 ! beta-1,3-galactosyltransferase activity GO:0048531 8 8 0,000 4,336E-03 0,01348916 ! establishment of pigment granule localization GO:0051905 8 8 0,000 4,336E-03 0,01347742 ! regulation of telomere maintenance GO:0032204 8 8 0,000 4,336E-03 0,01346571 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 4,336E-03 0,01345401 ! amino sugar catabolic process GO:0046348 8 8 0,000 4,336E-03 0,01344233 GO:0006043|glucosamine catabolic process, ! regulation of amino acid transport GO:0051955 8 8 0,000 4,336E-03 0,01343067 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 4,336E-03 0,01341903 ! T cell receptor signaling pathway GO:0050852 13 8 0,000 4,336E-03 0,01340741 ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 8 0,000 4,336E-03 0,01339581 ! cholesterol transporter activity GO:0017127 8 8 0,000 4,336E-03 0,01338424 ! GABA receptor binding GO:0050811 8 8 0,000 4,336E-03 0,01337268 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 8 8 0,000 4,336E-03 0,01336114 ! regulation of microtubule polymerization GO:0031113 8 8 0,000 4,336E-03 0,01334962 ! regulation of developmental growth GO:0048638 8 8 0,000 4,336E-03 0,01333812 ! GMP binding GO:0019002 10 8 0,000 4,336E-03 0,01332664 GO:0030553|cGMP binding, ! regulation of epithelial cell differentiation GO:0030856 8 8 0,000 4,336E-03 0,01331519 ! negative regulation of cellular catabolic process GO:0031330 9 8 0,000 4,336E-03 0,01330375 ! prostate gland development GO:0030850 8 8 0,000 4,336E-03 0,01329233 ! 7S RNA binding GO:0008312 9 8 0,000 4,336E-03 0,01328093 ! phosphate transport GO:0006817 9 8 0,000 4,336E-03 0,01326955 ! neutral lipid catabolic process GO:0046461 8 8 0,000 4,336E-03 0,01325819 ! protein phosphorylated amino acid binding GO:0045309 10 8 0,000 4,336E-03 0,01324684 ! reproductive behavior GO:0019098 8 8 0,000 4,336E-03 0,01323552 ! cell volume homeostasis GO:0006884 9 8 0,000 4,336E-03 0,01322422 ! regulation of long-term neuronal synaptic plasticity GO:0048169 8 8 0,000 4,336E-03 0,01321294 ! oligopeptide transport GO:0006857 8 8 0,000 4,336E-03 0,01320167 GO:0015198|oligopeptide transporter activity, ! induction of positive chemotaxis GO:0050930 8 8 0,000 4,336E-03 0,01319043 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 4,336E-03 0,0131792 ! regulation of dopamine metabolic process GO:0042053 8 8 0,000 4,336E-03 0,01316799 GO:0042069|regulation of catecholamine metabolic process, ! regulation of carbohydrate biosynthetic process GO:0043255 8 8 0,000 4,336E-03 0,01315681 ! titin binding GO:0031432 8 8 0,000 4,336E-03 0,01314564 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 4,336E-03 0,01313449 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 8 0,000 4,336E-03 0,01312336 ! bone resorption GO:0045453 8 8 0,000 4,336E-03 0,01311224 ! glycerolipid catabolic process GO:0046503 8 8 0,000 4,336E-03 0,01310115 ! endoderm development GO:0007492 8 8 0,000 4,336E-03 0,01309008 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 4,336E-03 0,01307902 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 4,336E-03 0,01306798 ! embryonic cranial skeleton morphogenesis GO:0048701 8 8 0,000 4,336E-03 0,01305697 ! syncytium formation GO:0006949 8 8 0,000 4,336E-03 0,01304597 ! embryonic eye morphogenesis GO:0048048 10 8 0,000 4,336E-03 0,01303498 ! B cell proliferation GO:0042100 8 8 0,000 4,336E-03 0,01302402 ! mannose metabolic process GO:0006013 10 8 0,000 4,336E-03 0,01301308 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 8 8 0,000 4,336E-03 0,01300215 ! asymmetric protein localization GO:0008105 8 8 0,000 4,336E-03 0,01299124 ! tumor necrosis factor binding GO:0043120 8 8 0,000 4,336E-03 0,01298035 ! synaptic transmission, glutamatergic GO:0035249 9 8 0,000 4,336E-03 0,01296948 ! neuron apoptosis GO:0051402 8 8 0,000 4,336E-03 0,01295863 ! macroautophagy GO:0016236 9 8 0,000 4,336E-03 0,01294779 ! Cajal body GO:0015030 8 8 0,000 4,336E-03 0,01293698 ! O-methyltransferase activity GO:0008171 9 8 0,000 4,336E-03 0,01292618 ! H4/H2A histone acetyltransferase complex GO:0043189 9 8 0,000 4,336E-03 0,0129154 ! PcG protein complex GO:0031519 8 8 0,000 4,336E-03 0,01290463 ! ferric iron binding GO:0008199 9 8 0,000 4,336E-03 0,01289389 ! spindle checkpoint GO:0031577 8 8 0,000 4,336E-03 0,01288316 ! G1 DNA damage checkpoint GO:0031571 8 8 0,000 4,336E-03 0,01287245 ! segment specification GO:0007379 8 8 0,000 4,336E-03 0,01286176 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 4,336E-03 0,01285109 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 4,336E-03 0,01284043 ! cellular extravasation GO:0045123 9 8 0,000 4,336E-03 0,01282979 ! pronucleus GO:0045120 8 8 0,000 4,336E-03 0,01281917 ! regulation of insulin receptor signaling pathway GO:0046626 8 8 0,000 4,336E-03 0,01280857 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 8 8 0,000 4,336E-03 0,01279798 ! Rac GTPase activator activity GO:0030675 9 8 0,000 4,336E-03 0,01278742 ! regulation of DNA repair GO:0006282 8 8 0,000 4,336E-03 0,01277687 ! transcription-coupled nucleotide-excision repair GO:0006283 9 8 0,000 4,336E-03 0,01276633 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 4,336E-03 0,01275582 ! antigen processing and presentation of exogenous antigen GO:0019884 9 8 0,000 4,336E-03 0,01274532 ! DNA ligation GO:0006266 8 8 0,000 4,336E-03 0,01273484 ! regulation of T cell differentiation in the thymus GO:0033081 8 8 0,000 4,336E-03 0,01272437 ! negative regulation of systemic arterial blood pressure GO:0003085 8 8 0,000 4,336E-03 0,01271393 ! multicellular organismal aging GO:0010259 8 8 0,000 4,336E-03 0,0127035 ! erythrocyte development GO:0048821 8 8 0,000 4,336E-03 0,01269308 ! interleukin-1 receptor activity GO:0004908 8 8 0,000 4,336E-03 0,01268269 ! positive regulation of monooxygenase activity GO:0032770 8 8 0,000 4,336E-03 0,01267231 ! protein import into peroxisome matrix GO:0016558 8 8 0,000 4,336E-03 0,01266195 ! gamma-tubulin binding GO:0043015 8 8 0,000 4,336E-03 0,0126516 ! ribosome binding GO:0043022 9 8 0,000 4,336E-03 0,01264127 ! NADPH oxidase complex GO:0043020 8 8 0,000 4,336E-03 0,01263096 ! mRNA polyadenylation GO:0006378 8 8 0,000 4,336E-03 0,01262067 ! sodium:amino acid symporter activity GO:0005283 8 8 0,000 4,336E-03 0,01261039 ! adenylyltransferase activity GO:0070566 8 8 0,000 4,336E-03 0,01260013 ! zymogen activation GO:0031638 8 8 0,000 4,336E-03 0,01258989 ! axonal fasciculation GO:0007413 8 8 0,000 4,336E-03 0,01257966 ! T cell homeostasis GO:0043029 9 8 0,000 4,336E-03 0,01256945 ! negative regulation of nuclear division GO:0051784 8 8 0,000 4,336E-03 0,01255925 GO:0045839|negative regulation of mitosis, ! caspase inhibitor activity GO:0043027 8 8 0,000 4,336E-03 0,01254908 ! energy coupled proton transport, against electrochemical gradient GO:0015988 8 8 0,000 4,336E-03 0,01253892 GO:0015991|ATP hydrolysis coupled proton transport, ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 8 8 0,000 4,336E-03 0,01252877 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 4,336E-03 0,01251864 ! thyroid hormone receptor activity GO:0004887 8 8 0,000 4,336E-03 0,01250853 ! wide pore channel activity GO:0022829 8 8 0,000 4,336E-03 0,01249844 ! ligand-regulated transcription factor activity GO:0003706 8 8 0,000 4,336E-03 0,01248836 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 4,336E-03 0,01247829 ! hormone catabolic process GO:0042447 8 8 0,000 4,336E-03 0,01246825 ! positive regulation of ATPase activity GO:0032781 8 8 0,000 4,336E-03 0,01245821 ! biogenic amine catabolic process GO:0042402 11 8 0,000 4,336E-03 0,0124482 ! Notch binding GO:0005112 8 8 0,000 4,336E-03 0,0124382 ! death receptor binding GO:0005123 8 8 0,000 4,336E-03 0,01242822 ! ATPase regulator activity GO:0060590 8 8 0,000 4,336E-03 0,01241825 ! pyrimidine base metabolic process GO:0006206 10 8 0,000 4,336E-03 0,0124083 ! epidermal growth factor receptor binding GO:0005154 9 8 0,000 4,336E-03 0,01239837 ! dihydropyridine-sensitive calcium channel activity GO:0015270 8 8 0,000 4,336E-03 0,01238845 ! calcium-release channel activity GO:0015278 8 8 0,000 4,336E-03 0,01237855 ! tubulin-tyrosine ligase activity GO:0004835 8 8 0,000 4,336E-03 0,01236866 ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 4,336E-03 0,01235879 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 8 8 0,000 4,336E-03 0,01234893 ! nucleus localization GO:0051647 10 8 0,000 4,336E-03 0,01233909 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 4,336E-03 0,01232927 ! negative regulation of immune effector process GO:0002698 12 8 0,000 4,336E-03 0,01231946 ! C-X-C chemokine receptor activity GO:0016494 8 8 0,000 4,336E-03 0,01230967 ! adenosine deaminase activity GO:0004000 8 8 0,000 4,336E-03 0,01229989 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9 9 0,000 4,877E-03 0,01382311 ! respiratory burst GO:0045730 9 9 0,000 4,877E-03 0,01381215 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 9 9 0,000 4,877E-03 0,0138012 ! telencephalon cell migration GO:0022029 9 9 0,000 4,877E-03 0,01379028 ! 'de novo' posttranslational protein folding GO:0051084 9 9 0,000 4,877E-03 0,01377937 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 4,877E-03 0,01376847 ! cGMP metabolic process GO:0046068 9 9 0,000 4,877E-03 0,0137576 GO:0006182|cGMP biosynthetic process, ! regulation of epidermal growth factor receptor activity GO:0007176 9 9 0,000 4,877E-03 0,01374674 GO:0010469|regulation of receptor activity, ! inositol trisphosphate phosphatase activity GO:0046030 11 9 0,000 4,877E-03 0,0137359 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! axon part GO:0033267 12 9 0,000 4,877E-03 0,01372507 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9 9 0,000 4,877E-03 0,01371427 ! RNA polyadenylation GO:0043631 9 9 0,000 4,877E-03 0,01370348 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 9 0,000 4,877E-03 0,0136927 ! regulation of receptor-mediated endocytosis GO:0048259 9 9 0,000 4,877E-03 0,01368195 ! artery development GO:0060840 9 9 0,000 4,877E-03 0,01367121 GO:0048844|artery morphogenesis, ! photoreceptor cell development GO:0042461 12 9 0,000 4,877E-03 0,01366049 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 9 9 0,000 4,877E-03 0,01364978 ! middle ear morphogenesis GO:0042474 9 9 0,000 4,877E-03 0,01363909 ! regulation of mesenchymal cell proliferation GO:0010464 9 9 0,000 4,877E-03 0,01362842 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 12 9 0,000 4,877E-03 0,01361776 GO:0046330|positive regulation of JNK cascade, ! positive regulation of heart contraction GO:0045823 10 9 0,000 4,877E-03 0,01360712 ! lung alveolus development GO:0048286 9 9 0,000 4,877E-03 0,0135965 ! ciliary or flagellar motility GO:0001539 9 9 0,000 4,877E-03 0,0135859 ! beta-amyloid binding GO:0001540 10 9 0,000 4,877E-03 0,01357531 ! pathogenesis GO:0009405 9 9 0,000 4,877E-03 0,01356473 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 10 9 0,000 4,877E-03 0,01355418 ! regulated secretory pathway GO:0045055 9 9 0,000 4,877E-03 0,01354364 ! regulation of S phase of mitotic cell cycle GO:0007090 9 9 0,000 4,877E-03 0,01353311 ! estrogen receptor binding GO:0030331 9 9 0,000 4,877E-03 0,01352261 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 10 9 0,000 4,877E-03 0,01351212 ! regulation of defense response to virus by virus GO:0050690 9 9 0,000 4,877E-03 0,01350164 ! histidine metabolic process GO:0006547 9 9 0,000 4,877E-03 0,01349118 GO:0009075|histidine family amino acid metabolic process, ! L-phenylalanine metabolic process GO:0006558 10 9 0,000 4,877E-03 0,01348074 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 9 9 0,000 4,877E-03 0,01347032 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 9 9 0,000 4,877E-03 0,01345991 ! nucleobase biosynthetic process GO:0046112 11 9 0,000 4,877E-03 0,01344951 ! regulation of Cdc42 protein signal transduction GO:0032489 9 9 0,000 4,877E-03 0,01343913 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of calcium ion transport into cytosol GO:0010522 12 9 0,000 4,877E-03 0,01342877 ! entry into host cell GO:0030260 9 9 0,000 4,877E-03 0,01341843 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 9 9 0,000 4,877E-03 0,0134081 ! regulation of lipoprotein lipase activity GO:0051004 9 9 0,000 4,877E-03 0,01339778 ! retinoic acid metabolic process GO:0042573 9 9 0,000 4,877E-03 0,01338749 ! retinol metabolic process GO:0042572 9 9 0,000 4,877E-03 0,0133772 ! behavioral fear response GO:0001662 9 9 0,000 4,877E-03 0,01336694 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 10 9 0,000 4,877E-03 0,01335669 ! regulation of vascular endothelial growth factor production GO:0010574 9 9 0,000 4,877E-03 0,01334645 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9 9 0,000 4,877E-03 0,01333623 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! motor axon guidance GO:0008045 9 9 0,000 4,877E-03 0,01332603 ! regulation of gliogenesis GO:0014013 9 9 0,000 4,877E-03 0,01331584 GO:0045685|regulation of glial cell differentiation, ! recycling endosome membrane GO:0055038 10 9 0,000 4,877E-03 0,01330567 ! pigment granule localization GO:0051875 9 9 0,000 4,877E-03 0,01329551 ! platelet-derived growth factor binding GO:0048407 10 9 0,000 4,877E-03 0,01328537 ! glycosphingolipid biosynthetic process GO:0006688 9 9 0,000 4,877E-03 0,01327524 ! nucleoside diphosphate metabolic process GO:0009132 10 9 0,000 4,877E-03 0,01326513 ! phosphoinositide 3-kinase cascade GO:0014065 9 9 0,000 4,877E-03 0,01325504 ! cell wall macromolecule catabolic process GO:0016998 10 9 0,000 4,877E-03 0,01324496 ! purine ribonucleotide catabolic process GO:0009154 9 9 0,000 4,877E-03 0,01323489 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 9 9 0,000 4,877E-03 0,01322484 ! nitric oxide metabolic process GO:0046209 9 9 0,000 4,877E-03 0,01321481 GO:0006809|nitric oxide biosynthetic process, ! mismatch repair complex GO:0032300 9 9 0,000 4,877E-03 0,01320479 ! icosanoid secretion GO:0032309 9 9 0,000 4,877E-03 0,01319479 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 10 9 0,000 4,877E-03 0,0131848 GO:0010092|specification of organ identity, ! retinal ganglion cell axon guidance GO:0031290 9 9 0,000 4,877E-03 0,01317482 ! morphogenesis of a polarized epithelium GO:0001738 9 9 0,000 4,877E-03 0,01316487 ! sterol catabolic process GO:0016127 9 9 0,000 4,877E-03 0,01315492 GO:0006707|cholesterol catabolic process, ! prophase GO:0051324 9 9 0,000 4,877E-03 0,013145 ! peptidyl-lysine modification GO:0018205 9 9 0,000 4,877E-03 0,01313508 ! pancreatic ribonuclease activity GO:0004522 9 9 0,000 4,877E-03 0,01312518 ! clathrin coat of coated pit GO:0030132 12 9 0,000 4,877E-03 0,0131153 ! SNARE complex GO:0031201 10 9 0,000 4,877E-03 0,01310543 ! ubiquinone metabolic process GO:0006743 10 9 0,000 4,877E-03 0,01309558 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! snRNA binding GO:0017069 9 9 0,000 4,877E-03 0,01308574 ! regulation of macrophage differentiation GO:0045649 9 9 0,000 4,877E-03 0,01307591 ! regulation of osteoclast differentiation GO:0045670 10 9 0,000 4,877E-03 0,01306611 ! positive regulation of neuron differentiation GO:0045666 9 9 0,000 4,877E-03 0,01305631 ! negative regulation of lymphocyte differentiation GO:0045620 9 9 0,000 4,877E-03 0,01304653 ! methionine biosynthetic process GO:0009086 10 9 0,000 4,877E-03 0,01303677 ! peptidoglycan binding GO:0042834 9 9 0,000 4,877E-03 0,01302701 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 4,877E-03 0,01301728 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! pyridine nucleotide biosynthetic process GO:0019363 9 9 0,000 4,877E-03 0,01300756 ! intramolecular transferase activity, phosphotransferases GO:0016868 9 9 0,000 4,877E-03 0,01299785 ! cholesterol efflux GO:0033344 9 9 0,000 4,877E-03 0,01298816 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 9 9 0,000 4,877E-03 0,01297848 ! metalloenzyme inhibitor activity GO:0048551 10 9 0,000 4,877E-03 0,01296881 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! leukocyte mediated cytotoxicity GO:0001909 9 9 0,000 4,877E-03 0,01295917 ! anterior/posterior axis specification GO:0009948 9 9 0,000 4,877E-03 0,01294953 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 4,877E-03 0,01293991 ! detection of calcium ion GO:0005513 10 9 0,000 4,877E-03 0,0129303 ! negative regulation of glucose import GO:0046325 9 9 0,000 4,877E-03 0,01292071 GO:0010829|negative regulation of glucose transport, ! regulation of fibrinolysis GO:0051917 9 9 0,000 4,877E-03 0,01291113 ! trophectodermal cell differentiation GO:0001829 9 9 0,000 4,877E-03 0,01290157 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 9 0,000 4,877E-03 0,01289202 ! hydrolase activity, acting on ether bonds GO:0016801 9 9 0,000 4,877E-03 0,01288248 ! desmosome GO:0030057 9 9 0,000 4,877E-03 0,01287296 ! prepulse inhibition GO:0060134 9 9 0,000 4,877E-03 0,01286346 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 9 0,000 4,877E-03 0,01285396 ! negative regulation of B cell activation GO:0050869 9 9 0,000 4,877E-03 0,01284448 ! anchoring collagen GO:0030934 9 9 0,000 4,877E-03 0,01283502 ! axon extension GO:0048675 10 9 0,000 4,877E-03 0,01282557 ! neuron fate specification GO:0048665 9 9 0,000 4,877E-03 0,01281613 ! positive regulation of glucose metabolic process GO:0010907 9 9 0,000 4,877E-03 0,0128067 ! cortical actin cytoskeleton organization GO:0030866 9 9 0,000 4,877E-03 0,0127973 ! virus-host interaction GO:0019048 13 9 0,000 4,877E-03 0,0127879 ! rough endoplasmic reticulum membrane GO:0030867 9 9 0,000 4,877E-03 0,01277852 ! pentose-phosphate shunt GO:0006098 9 9 0,000 4,877E-03 0,01276915 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 4,877E-03 0,01275979 ! DNA bending activity GO:0008301 9 9 0,000 4,877E-03 0,01275045 ! social behavior GO:0035176 9 9 0,000 4,877E-03 0,01274113 ! secondary active sulfate transmembrane transporter activity GO:0008271 9 9 0,000 4,877E-03 0,01273181 ! dipeptidyl-peptidase activity GO:0008239 11 9 0,000 4,877E-03 0,01272251 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 4,877E-03 0,01271323 ! very-low-density lipoprotein particle GO:0034361 9 9 0,000 4,877E-03 0,01270395 GO:0034385|triglyceride-rich lipoprotein particle, ! high-density lipoprotein particle GO:0034364 9 9 0,000 4,877E-03 0,01269469 ! amyloid precursor protein metabolic process GO:0042982 10 9 0,000 4,877E-03 0,01268545 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 11 9 0,000 4,877E-03 0,01267621 ! blood vessel remodeling GO:0001974 10 9 0,000 4,877E-03 0,012667 ! C-X-C chemokine binding GO:0019958 9 9 0,000 4,877E-03 0,01265779 ! 3'-5'-exoribonuclease activity GO:0000175 9 9 0,000 4,877E-03 0,0126486 ! exosome (RNase complex) GO:0000178 9 9 0,000 4,877E-03 0,01263942 ! inositol phosphate-mediated signaling GO:0048016 9 9 0,000 4,877E-03 0,01263025 ! DNA N-glycosylase activity GO:0019104 9 9 0,000 4,877E-03 0,0126211 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 9 9 0,000 4,877E-03 0,01261196 GO:0033549|MAP kinase phosphatase activity, ! ER overload response GO:0006983 11 9 0,000 4,877E-03 0,01260284 ! zinc ion transmembrane transporter activity GO:0005385 9 9 0,000 4,877E-03 0,01259372 ! glucose transmembrane transporter activity GO:0005355 9 9 0,000 4,877E-03 0,01258462 ! retrograde transport, endosome to Golgi GO:0042147 10 9 0,000 4,877E-03 0,01257554 ! phagocytosis, engulfment GO:0006911 10 9 0,000 4,877E-03 0,01256646 ! neurotransmitter biosynthetic process GO:0042136 10 9 0,000 4,877E-03 0,0125574 ! carbohydrate phosphatase activity GO:0019203 9 9 0,000 4,877E-03 0,01254836 ! glutathione peroxidase activity GO:0004602 9 9 0,000 4,877E-03 0,01253932 ! acyl-CoA thioesterase activity GO:0016291 9 9 0,000 4,877E-03 0,0125303 ! lysophospholipase activity GO:0004622 9 9 0,000 4,877E-03 0,01252129 ! brain morphogenesis GO:0048854 9 9 0,000 4,877E-03 0,0125123 ! apolipoprotein binding GO:0034185 9 9 0,000 4,877E-03 0,01250332 ! synaptic vesicle membrane GO:0030672 9 9 0,000 4,877E-03 0,01249435 ! RNA-dependent DNA replication GO:0006278 9 9 0,000 4,877E-03 0,01248539 ! positive regulation of systemic arterial blood pressure GO:0003084 10 9 0,000 4,877E-03 0,01247645 ! kinesin binding GO:0019894 9 9 0,000 4,877E-03 0,01246752 ! nucleoside bisphosphate metabolic process GO:0033865 10 9 0,000 4,877E-03 0,0124586 ! renal water homeostasis GO:0003091 9 9 0,000 4,877E-03 0,01244969 ! positive regulation of interleukin-6 production GO:0032755 9 9 0,000 4,877E-03 0,0124408 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 4,877E-03 0,01243192 ! histone methylation GO:0016571 10 9 0,000 4,877E-03 0,01242305 ! mRNA cleavage GO:0006379 9 9 0,000 4,877E-03 0,0124142 ! negative regulation of tumor necrosis factor production GO:0032720 9 9 0,000 4,877E-03 0,01240536 ! regulation of transcription from RNA polymerase III promoter GO:0006359 9 9 0,000 4,877E-03 0,01239653 ! sarcoplasmic reticulum membrane GO:0033017 10 9 0,000 4,877E-03 0,01238771 ! opioid receptor activity GO:0004985 9 9 0,000 4,877E-03 0,0123789 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 4,877E-03 0,01237011 ! salivary gland development GO:0007431 10 9 0,000 4,877E-03 0,01236133 ! glucosidase activity GO:0015926 10 9 0,000 4,877E-03 0,01235257 ! adrenoceptor activity GO:0004935 11 9 0,000 4,877E-03 0,01234381 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 9 9 0,000 4,877E-03 0,01233507 ! positive regulation of leukocyte migration GO:0002687 9 9 0,000 4,877E-03 0,01232634 ! purine base metabolic process GO:0006144 11 9 0,000 4,877E-03 0,01231762 ! mRNA 3'-UTR binding GO:0003730 9 9 0,000 4,877E-03 0,01230892 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 9 9 0,000 4,877E-03 0,01230022 ! receptor inhibitor activity GO:0030547 9 9 0,000 4,877E-03 0,01229154 GO:0048019|receptor antagonist activity, ! negative regulation of BMP signaling pathway GO:0030514 9 9 0,000 4,877E-03 0,01228288 ! ionotropic glutamate receptor complex GO:0008328 11 9 0,000 4,877E-03 0,01227422 ! transforming growth factor beta receptor binding GO:0005160 9 9 0,000 4,877E-03 0,01226558 ! palmitoyltransferase activity GO:0016409 9 9 0,000 4,877E-03 0,01225694 ! arylsulfatase activity GO:0004065 9 9 0,000 4,877E-03 0,01224833 ! phospholipase inhibitor activity GO:0004859 9 9 0,000 4,877E-03 0,01223972 ! behavioral response to nicotine GO:0035095 9 9 0,000 4,877E-03 0,01223112 ! adenylate kinase activity GO:0004017 10 9 0,000 4,877E-03 0,01222254 ! alcohol dehydrogenase (NAD) activity GO:0004022 9 9 0,000 4,877E-03 0,01221397 ! mitochondrion localization GO:0051646 9 9 0,000 4,877E-03 0,01220541 ! localization within membrane GO:0051668 9 9 0,000 4,877E-03 0,01219686 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 10 0,000 5,418E-03 0,01353937 ! lipid particle GO:0005811 10 10 0,000 5,418E-03 0,0135299 ! myotube differentiation GO:0014902 10 10 0,000 5,418E-03 0,01352045 ! generation of neurons in the forebrain GO:0021872 11 10 0,000 5,418E-03 0,013511 ! regulation of cellular amine metabolic process GO:0033238 10 10 0,000 5,418E-03 0,01350158 ! synapsis GO:0007129 10 10 0,000 5,418E-03 0,01349216 GO:0070192|chromosome organization involved in meiosis, ! filopodium assembly GO:0046847 12 10 0,000 5,418E-03 0,01348276 ! UTP metabolic process GO:0046051 10 10 0,000 5,418E-03 0,01347337 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 10 10 0,000 5,418E-03 0,01346399 ! COPI coating of Golgi vesicle GO:0048205 10 10 0,000 5,418E-03 0,01345463 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 10 10 0,000 5,418E-03 0,01344528 ! platelet alpha granule membrane GO:0031092 11 10 0,000 5,418E-03 0,01343594 ! macromolecule transmembrane transporter activity GO:0022884 10 10 0,000 5,418E-03 0,01342662 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! lipoprotein receptor binding GO:0070325 10 10 0,000 5,418E-03 0,01341731 GO:0050750|low-density lipoprotein receptor binding, ! thyroid hormone receptor coactivator activity GO:0030375 10 10 0,000 5,418E-03 0,01340801 GO:0010861|thyroid hormone receptor activator activity, ! auditory receptor cell differentiation GO:0042491 11 10 0,000 5,418E-03 0,01339872 ! regulation of chemokine biosynthetic process GO:0045073 10 10 0,000 5,418E-03 0,01338945 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 10 10 0,000 5,418E-03 0,01338019 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 5,418E-03 0,01337095 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 10 0,000 5,418E-03 0,01336171 ! nucleotide-sugar metabolic process GO:0009225 11 10 0,000 5,418E-03 0,01335249 ! regulation of catecholamine secretion GO:0050433 10 10 0,000 5,418E-03 0,01334328 ! melanocyte differentiation GO:0030318 10 10 0,000 5,418E-03 0,01333409 GO:0050931|pigment cell differentiation, ! ER-Golgi intermediate compartment membrane GO:0033116 10 10 0,000 5,418E-03 0,0133249 ! deoxyribonucleotide catabolic process GO:0009264 10 10 0,000 5,418E-03 0,01331573 ! L-serine metabolic process GO:0006563 11 10 0,000 5,418E-03 0,01330657 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 10 10 0,000 5,418E-03 0,01329743 ! lipase inhibitor activity GO:0055102 10 10 0,000 5,418E-03 0,0132883 ! autophagic vacuole GO:0005776 11 10 0,000 5,418E-03 0,01327917 ! NAD metabolic process GO:0019674 10 10 0,000 5,418E-03 0,01327007 ! stereocilium GO:0032420 10 10 0,000 5,418E-03 0,01326097 GO:0032421|stereocilium bundle, ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 5,418E-03 0,01325189 ! regulation of sodium ion transport GO:0002028 10 10 0,000 5,418E-03 0,01324282 ! forebrain cell migration GO:0021885 10 10 0,000 5,418E-03 0,01323376 ! organelle subcompartment GO:0031984 11 10 0,000 5,418E-03 0,01322471 ! chondrocyte differentiation GO:0002062 10 10 0,000 5,418E-03 0,01321568 ! negative regulation of ossification GO:0030279 10 10 0,000 5,418E-03 0,01320666 ! regulation of smoothened signaling pathway GO:0008589 10 10 0,000 5,418E-03 0,01319765 ! heparan sulfate proteoglycan metabolic process GO:0030201 10 10 0,000 5,418E-03 0,01318866 ! phosphatidylcholine biosynthetic process GO:0006656 12 10 0,000 5,418E-03 0,01317967 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 10 10 0,000 5,418E-03 0,0131707 ! protein homotetramerization GO:0051289 11 10 0,000 5,418E-03 0,01316174 ! positive regulation of phagocytosis GO:0050766 10 10 0,000 5,418E-03 0,01315279 ! response to dsRNA GO:0043331 10 10 0,000 5,418E-03 0,01314386 ! mismatch repair complex binding GO:0032404 11 10 0,000 5,418E-03 0,01313493 ! snRNA metabolic process GO:0016073 10 10 0,000 5,418E-03 0,01312602 GO:0016180|snRNA processing, ! cranial nerve development GO:0021545 10 10 0,000 5,418E-03 0,01311712 ! fucose catabolic process GO:0019317 11 10 0,000 5,418E-03 0,01310824 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 10 10 0,000 5,418E-03 0,01309936 ! retinal binding GO:0016918 10 10 0,000 5,418E-03 0,0130905 ! leukocyte activation during immune response GO:0002366 10 10 0,000 5,418E-03 0,01308165 GO:0002263|cell activation during immune response, ! cerebellum morphogenesis GO:0021587 11 10 0,000 5,418E-03 0,01307281 GO:0021696|cerebellar cortex morphogenesis, ! photoreceptor outer segment GO:0001750 10 10 0,000 5,418E-03 0,01306398 ! negative regulation of MAPKKK cascade GO:0043409 10 10 0,000 5,418E-03 0,01305517 ! regulation of T-helper 2 type immune response GO:0002828 10 10 0,000 5,418E-03 0,01304636 ! ribonuclease P activity GO:0004526 10 10 0,000 5,418E-03 0,01303757 ! midbrain development GO:0030901 10 10 0,000 5,418E-03 0,01302879 ! musculoskeletal movement GO:0050881 10 10 0,000 5,418E-03 0,01302003 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 10 10 0,000 5,418E-03 0,01301127 ! regulation of T-helper cell differentiation GO:0045622 10 10 0,000 5,418E-03 0,01300253 ! fatty-acid ligase activity GO:0015645 10 10 0,000 5,418E-03 0,01299379 GO:0004467|long-chain-fatty-acid-CoA ligase activity, ! regulation of mRNA stability GO:0043488 10 10 0,000 5,418E-03 0,01298507 ! quaternary ammonium group transport GO:0015697 10 10 0,000 5,418E-03 0,01297636 ! regulation of RNA splicing GO:0043484 10 10 0,000 5,418E-03 0,01296767 ! embryonic gut development GO:0048566 10 10 0,000 5,418E-03 0,01295898 ! positive regulation of amine transport GO:0051954 10 10 0,000 5,418E-03 0,01295031 ! defense response to Gram-positive bacterium GO:0050830 10 10 0,000 5,418E-03 0,01294164 ! mRNA 3'-end processing GO:0031124 10 10 0,000 5,418E-03 0,01293299 ! lysogeny GO:0030069 10 10 0,000 5,418E-03 0,01292435 GO:0019047|provirus integration, ! lamellipodium assembly GO:0030032 11 10 0,000 5,418E-03 0,01291573 ! establishment of cell polarity GO:0030010 10 10 0,000 5,418E-03 0,01290711 ! regulation of synapse organization GO:0050807 10 10 0,000 5,418E-03 0,01289851 ! cell wall macromolecule metabolic process GO:0044036 11 10 0,000 5,418E-03 0,01288991 ! acyl-CoA binding GO:0000062 10 10 0,000 5,418E-03 0,01288133 ! negative regulation of muscle development GO:0048635 11 10 0,000 5,418E-03 0,01287276 GO:0045843|negative regulation of striated muscle development, ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 5,418E-03 0,0128642 ! GDP binding GO:0019003 10 10 0,000 5,418E-03 0,01285565 ! photoreceptor activity GO:0009881 10 10 0,000 5,418E-03 0,01284712 ! somatic diversification of immune receptors via somatic mutation GO:0002566 10 10 0,000 5,418E-03 0,01283859 GO:0016446|somatic hypermutation of immunoglobulin genes, ! cortical cytoskeleton organization GO:0030865 10 10 0,000 5,418E-03 0,01283008 ! nitric-oxide synthase binding GO:0050998 11 10 0,000 5,418E-03 0,01282158 ! nuclear chromosome, telomeric region GO:0000784 10 10 0,000 5,418E-03 0,01281308 ! nucleotidase activity GO:0008252 10 10 0,000 5,418E-03 0,0128046 ! detection of mechanical stimulus GO:0050982 10 10 0,000 5,418E-03 0,01279614 ! protein complex disassembly GO:0043241 11 10 0,000 5,418E-03 0,01278768 GO:0043624|cellular protein complex disassembly, ! androgen metabolic process GO:0008209 10 10 0,000 5,418E-03 0,01277923 ! lateral plasma membrane GO:0016328 10 10 0,000 5,418E-03 0,0127708 ! estrogen metabolic process GO:0008210 10 10 0,000 5,418E-03 0,01276237 ! nucleocytoplasmic transporter activity GO:0005487 10 10 0,000 5,418E-03 0,01275396 ! retinol dehydrogenase activity GO:0004745 10 10 0,000 5,418E-03 0,01274556 ! negative regulation of cell-matrix adhesion GO:0001953 12 10 0,000 5,418E-03 0,01273717 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 11 10 0,000 5,418E-03 0,01272879 ! interleukin-1 binding GO:0019966 10 10 0,000 5,418E-03 0,01272042 ! endothelial cell differentiation GO:0045446 10 10 0,000 5,418E-03 0,01271206 ! cullin-RING ubiquitin ligase complex GO:0031461 10 10 0,000 5,418E-03 0,01270371 ! acid phosphatase activity GO:0003993 10 10 0,000 5,418E-03 0,01269538 ! sodium:potassium-exchanging ATPase activity GO:0005391 11 10 0,000 5,418E-03 0,01268705 ! calcium-transporting ATPase activity GO:0005388 12 10 0,000 5,418E-03 0,01267874 ! telomeric DNA binding GO:0042162 11 10 0,000 5,418E-03 0,01267044 ! regulation of intracellular pH GO:0051453 10 10 0,000 5,418E-03 0,01266215 ! lipid digestion GO:0044241 10 10 0,000 5,418E-03 0,01265386 ! multicellular organism growth GO:0035264 10 10 0,000 5,418E-03 0,01264559 ! receptor clustering GO:0043113 10 10 0,000 5,418E-03 0,01263733 ! L-glutamate transmembrane transporter activity GO:0005313 10 10 0,000 5,418E-03 0,01262908 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 11 10 0,000 5,418E-03 0,01262085 ! adult heart development GO:0007512 12 10 0,000 5,418E-03 0,01261262 ! actin cytoskeleton reorganization GO:0031532 12 10 0,000 5,418E-03 0,0126044 ! signalosome GO:0008180 10 10 0,000 5,418E-03 0,0125962 ! prefoldin complex GO:0016272 10 10 0,000 5,418E-03 0,012588 ! neuromuscular junction GO:0031594 10 10 0,000 5,418E-03 0,01257982 ! regulation of bone resorption GO:0045124 11 10 0,000 5,418E-03 0,01257164 ! positive regulation of peptide secretion GO:0002793 10 10 0,000 5,418E-03 0,01256348 ! alpha-beta T cell differentiation GO:0046632 11 10 0,000 5,418E-03 0,01255533 ! negative regulation of myeloid leukocyte differentiation GO:0002762 10 10 0,000 5,418E-03 0,01254718 ! positive regulation of T cell mediated immunity GO:0002711 14 10 0,000 5,418E-03 0,01253905 ! taste receptor activity GO:0008527 10 10 0,000 5,418E-03 0,01253093 ! Ran GTPase binding GO:0008536 10 10 0,000 5,418E-03 0,01252282 ! endocytic vesicle membrane GO:0030666 10 10 0,000 5,418E-03 0,01251472 ! regulation of interleukin-12 production GO:0032655 10 10 0,000 5,418E-03 0,01250663 ! ribosome assembly GO:0042255 10 10 0,000 5,418E-03 0,01249855 ! DNA methylation GO:0006306 12 10 0,000 5,418E-03 0,01249048 GO:0006305|DNA alkylation, ! protein-hormone receptor activity GO:0016500 10 10 0,000 5,418E-03 0,01248242 ! bile acid transmembrane transporter activity GO:0015125 10 10 0,000 5,418E-03 0,01247438 ! proteasome accessory complex GO:0022624 11 10 0,000 5,418E-03 0,01246634 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 13 10 0,000 5,418E-03 0,01245831 ! prostaglandin receptor activity GO:0004955 11 10 0,000 5,418E-03 0,01245029 ! regulation of isotype switching GO:0045191 14 10 0,000 5,418E-03 0,01244229 ! peptide transporter activity GO:0015197 10 10 0,000 5,418E-03 0,01243429 ! regulation of leukocyte migration GO:0002685 10 10 0,000 5,418E-03 0,01242631 ! retinoid-X receptor activity GO:0004886 10 10 0,000 5,418E-03 0,01241833 ! GTPase inhibitor activity GO:0005095 10 10 0,000 5,418E-03 0,01241036 ! pattern recognition receptor activity GO:0008329 10 10 0,000 5,418E-03 0,01240241 ! gamma-tubulin complex GO:0000930 12 10 0,000 5,418E-03 0,01239446 ! germ cell migration GO:0008354 10 10 0,000 5,418E-03 0,01238653 ! regulation of organic acid transport GO:0032890 10 10 0,000 5,418E-03 0,0123786 ! negative regulation of mast cell proliferation GO:0070667 10 10 0,000 5,418E-03 0,01237069 GO:0042130|negative regulation of T cell proliferation, ! cardiac cell differentiation GO:0035051 11 10 0,000 5,418E-03 0,01236278 ! amiloride-sensitive sodium channel activity GO:0015280 10 10 0,000 5,418E-03 0,01235489 ! sterol transporter activity GO:0015248 10 10 0,000 5,418E-03 0,01234701 ! regulation of embryonic development GO:0045995 11 10 0,000 5,418E-03 0,01233913 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 11 11 0,000 5,958E-03 0,01356117 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 11 0,000 5,958E-03 0,01355253 ! negative regulation of blood pressure GO:0045776 11 11 0,000 5,958E-03 0,01354391 ! RNA cap binding GO:0000339 12 11 0,000 5,958E-03 0,01353529 ! CTP metabolic process GO:0046036 12 11 0,000 5,958E-03 0,01352669 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 11 0,000 5,958E-03 0,01351809 ! response to pain GO:0048265 11 11 0,000 5,958E-03 0,01350951 ! axonemal dynein complex GO:0005858 11 11 0,000 5,958E-03 0,01350094 ! eukaryotic translation initiation factor 3 complex GO:0005852 11 11 0,000 5,958E-03 0,01349238 ! dopamine receptor signaling pathway GO:0007212 13 11 0,000 5,958E-03 0,01348383 ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 11 0,000 5,958E-03 0,01347529 ! endocrine pancreas development GO:0031018 11 11 0,000 5,958E-03 0,01346676 ! regulation of interferon-gamma biosynthetic process GO:0045072 12 11 0,000 5,958E-03 0,01345824 ! regulation of exit from mitosis GO:0007096 11 11 0,000 5,958E-03 0,01344973 ! chylomicron GO:0042627 11 11 0,000 5,958E-03 0,01344124 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 11 11 0,000 5,958E-03 0,01343275 ! glycolipid biosynthetic process GO:0009247 11 11 0,000 5,958E-03 0,01342428 ! transforming growth factor beta binding GO:0050431 11 11 0,000 5,958E-03 0,01341581 ! glutamate metabolic process GO:0006536 12 11 0,000 5,958E-03 0,01340736 ! ribonucleotide catabolic process GO:0009261 11 11 0,000 5,958E-03 0,01339892 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 5,958E-03 0,01339048 ! vascular endothelial growth factor receptor activity GO:0005021 11 11 0,000 5,958E-03 0,01338206 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 11 11 0,000 5,958E-03 0,01337365 GO:0045125|bioactive lipid receptor activity, ! Rac GTPase binding GO:0048365 11 11 0,000 5,958E-03 0,01336525 ! epithelial cell development GO:0002064 11 11 0,000 5,958E-03 0,01335686 ! filamentous actin GO:0031941 11 11 0,000 5,958E-03 0,01334848 ! temperature homeostasis GO:0001659 11 11 0,000 5,958E-03 0,01334011 ! structural constituent of epidermis GO:0030280 13 11 0,000 5,958E-03 0,01333175 ! protein targeting to peroxisome GO:0006625 11 11 0,000 5,958E-03 0,01332341 ! spectrin GO:0008091 11 11 0,000 5,958E-03 0,01331507 ! cytoskeletal adaptor activity GO:0008093 14 11 0,000 5,958E-03 0,01330674 ! negative regulation of axonogenesis GO:0050771 13 11 0,000 5,958E-03 0,01329842 ! regulation of phagocytosis GO:0050764 11 11 0,000 5,958E-03 0,01329012 ! nucleoside triphosphate catabolic process GO:0009143 11 11 0,000 5,958E-03 0,01328182 ! synaptic vesicle exocytosis GO:0016079 12 11 0,000 5,958E-03 0,01327354 ! regulation of B cell differentiation GO:0045577 15 11 0,000 5,958E-03 0,01326526 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 11 11 0,000 5,958E-03 0,013257 ! basal lamina GO:0005605 12 11 0,000 5,958E-03 0,01324874 ! gastrulation with mouth forming second GO:0001702 12 11 0,000 5,958E-03 0,0132405 ! spinal cord motor neuron differentiation GO:0021522 11 11 0,000 5,958E-03 0,01323226 ! hindbrain morphogenesis GO:0021575 13 11 0,000 5,958E-03 0,01322404 ! regulation of hormone metabolic process GO:0032350 12 11 0,000 5,958E-03 0,01321583 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 11 0,000 5,958E-03 0,01320762 GO:0050706|regulation of interleukin-1 beta secretion, ! COPI vesicle coat GO:0030126 11 11 0,000 5,958E-03 0,01319943 GO:0030663|COPI coated vesicle membrane, ! clathrin coat of trans-Golgi network vesicle GO:0030130 14 11 0,000 5,958E-03 0,01319125 ! tRNA-specific ribonuclease activity GO:0004549 11 11 0,000 5,958E-03 0,01318307 ! cofactor transporter activity GO:0051184 11 11 0,000 5,958E-03 0,01317491 ! cobalt ion binding GO:0050897 11 11 0,000 5,958E-03 0,01316676 ! pseudouridine synthase activity GO:0009982 12 11 0,000 5,958E-03 0,01315861 ! aromatic amino acid family catabolic process GO:0009074 12 11 0,000 5,958E-03 0,01315048 ! serine family amino acid biosynthetic process GO:0009070 11 11 0,000 5,958E-03 0,01314236 ! histone deacetylase binding GO:0042826 11 11 0,000 5,958E-03 0,01313425 ! thymus development GO:0048538 12 11 0,000 5,958E-03 0,01312614 ! spleen development GO:0048536 12 11 0,000 5,958E-03 0,01311805 ! regulation of RNA stability GO:0043487 11 11 0,000 5,958E-03 0,01310997 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 12 11 0,000 5,958E-03 0,0131019 ! acid-thiol ligase activity GO:0016878 11 11 0,000 5,958E-03 0,01309383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 11 11 0,000 5,958E-03 0,01308578 ! blastocyst formation GO:0001825 11 11 0,000 5,958E-03 0,01307774 ! cerebellar cortex development GO:0021695 12 11 0,000 5,958E-03 0,0130697 ! ADP binding GO:0043531 11 11 0,000 5,958E-03 0,01306168 ! folic acid binding GO:0005542 11 11 0,000 5,958E-03 0,01305367 ! FK506 binding GO:0005528 11 11 0,000 5,958E-03 0,01304566 GO:0005527|macrolide binding, ! defense response to fungus GO:0050832 11 11 0,000 5,958E-03 0,01303767 ! extracellular matrix binding GO:0050840 13 11 0,000 5,958E-03 0,01302969 ! microspike assembly GO:0030035 13 11 0,000 5,958E-03 0,01302171 ! cytoplasmic sequestering of protein GO:0051220 11 11 0,000 5,958E-03 0,01301375 ! regulation of synapse structure and activity GO:0050803 11 11 0,000 5,958E-03 0,01300579 ! organ formation GO:0048645 12 11 0,000 5,958E-03 0,01299785 ! positive regulation of B cell proliferation GO:0030890 15 11 0,000 5,958E-03 0,01298991 ! embryonic hindlimb morphogenesis GO:0035116 11 11 0,000 5,958E-03 0,01298199 ! embryonic forelimb morphogenesis GO:0035115 11 11 0,000 5,958E-03 0,01297407 ! cellular copper ion homeostasis GO:0006878 12 11 0,000 5,958E-03 0,01296617 ! glycosaminoglycan catabolic process GO:0006027 11 11 0,000 5,958E-03 0,01295827 ! Golgi vesicle budding GO:0048194 11 11 0,000 5,958E-03 0,01295038 ! regulation of positive chemotaxis GO:0050926 11 11 0,000 5,958E-03 0,01294251 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 11 11 0,000 5,958E-03 0,01293464 ! ion channel inhibitor activity GO:0008200 13 11 0,000 5,958E-03 0,01292678 GO:0016248|channel inhibitor activity, ! positive regulation of transcription factor import into nucleus GO:0042993 12 11 0,000 5,958E-03 0,01291893 ! MAP kinase kinase activity GO:0004708 11 11 0,000 5,958E-03 0,01291109 GO:0004712|protein serine/threonine/tyrosine kinase activity, ! cation:amino acid symporter activity GO:0005416 11 11 0,000 5,958E-03 0,01290326 ! mannosyltransferase activity GO:0000030 11 11 0,000 5,958E-03 0,01289544 ! cAMP-dependent protein kinase activity GO:0004691 11 11 0,000 5,958E-03 0,01288763 ! FMN binding GO:0010181 11 11 0,000 5,958E-03 0,01287983 ! response to X-ray GO:0010165 12 11 0,000 5,958E-03 0,01287204 ! focal adhesion formation GO:0048041 13 11 0,000 5,958E-03 0,01286426 ! actin polymerization or depolymerization GO:0008154 13 11 0,000 5,958E-03 0,01285648 ! substrate-bound cell migration GO:0006929 11 11 0,000 5,958E-03 0,01284872 ! integrator complex GO:0032039 11 11 0,000 5,958E-03 0,01284097 ! UV protection GO:0009650 11 11 0,000 5,958E-03 0,01283322 ! L-glutamate transport GO:0015813 11 11 0,000 5,958E-03 0,01282548 GO:0015800|acidic amino acid transport, ! retinol binding GO:0019841 11 11 0,000 5,958E-03 0,01281776 ! regulation of organ growth GO:0046620 12 11 0,000 5,958E-03 0,01281004 ! regulation of cytokine production during immune response GO:0002718 11 11 0,000 5,958E-03 0,01280233 ! regulation of T cell mediated immunity GO:0002709 15 11 0,000 5,958E-03 0,01279464 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 11 11 0,000 5,958E-03 0,01278695 ! regulation of interleukin-8 production GO:0032677 12 11 0,000 5,958E-03 0,01277927 ! histone acetylation GO:0016573 11 11 0,000 5,958E-03 0,0127716 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 12 11 0,000 5,958E-03 0,01276393 ! delayed rectifier potassium channel activity GO:0005251 11 11 0,000 5,958E-03 0,01275628 ! organic cation transmembrane transporter activity GO:0015101 11 11 0,000 5,958E-03 0,01274864 ! chromatin silencing GO:0006342 11 11 0,000 5,958E-03 0,01274101 ! gland morphogenesis GO:0022612 12 11 0,000 5,958E-03 0,01273338 ! sulfate transmembrane transporter activity GO:0015116 11 11 0,000 5,958E-03 0,01272577 ! hexose transmembrane transporter activity GO:0015149 11 11 0,000 5,958E-03 0,01271816 ! icosanoid receptor activity GO:0004953 12 11 0,000 5,958E-03 0,01271056 GO:0004954|prostanoid receptor activity, ! non-G-protein coupled 7TM receptor activity GO:0004926 12 11 0,000 5,958E-03 0,01270297 ! negative regulation of neurological system process GO:0031645 12 11 0,000 5,958E-03 0,01269539 ! acid secretion GO:0046717 11 11 0,000 5,958E-03 0,01268782 ! nitric oxide mediated signal transduction GO:0007263 11 11 0,000 5,958E-03 0,01268026 ! thyroid hormone metabolic process GO:0042403 11 11 0,000 5,958E-03 0,01267271 ! quinone cofactor metabolic process GO:0042375 12 11 0,000 5,958E-03 0,01266517 ! insulin-like growth factor receptor binding GO:0005159 12 11 0,000 5,958E-03 0,01265763 ! midbody GO:0030496 11 11 0,000 5,958E-03 0,01265011 ! interferon-alpha/beta receptor binding GO:0005132 11 11 0,000 5,958E-03 0,01264259 ! cAMP-dependent protein kinase complex GO:0005952 11 11 0,000 5,958E-03 0,01263508 ! water channel activity GO:0015250 11 11 0,000 5,958E-03 0,01262758 ! response to nicotine GO:0035094 11 11 0,000 5,958E-03 0,01262009 ! response to cold GO:0009409 11 11 0,000 5,958E-03 0,01261261 ! adenylate cyclase activity GO:0004016 11 11 0,000 5,958E-03 0,01260514 ! 'de novo' protein folding GO:0006458 12 12 0,000 6,499E-03 0,01373966 ! centriole GO:0005814 12 12 0,000 6,499E-03 0,01373153 ! organellar large ribosomal subunit GO:0000315 13 12 0,000 6,499E-03 0,01372341 GO:0005762|mitochondrial large ribosomal subunit, ! cadmium ion binding GO:0046870 13 12 0,000 6,499E-03 0,0137153 ! folic acid and derivative biosynthetic process GO:0009396 12 12 0,000 6,499E-03 0,0137072 ! bone remodeling GO:0046849 12 12 0,000 6,499E-03 0,0136991 ! peroxisomal transport GO:0043574 12 12 0,000 6,499E-03 0,01369102 ! retina development in camera-type eye GO:0060041 13 12 0,000 6,499E-03 0,01368295 ! hair follicle morphogenesis GO:0031069 12 12 0,000 6,499E-03 0,01367489 ! voltage-gated sodium channel complex GO:0001518 13 12 0,000 6,499E-03 0,01366683 GO:0034706|sodium channel complex, ! regulation of excitatory postsynaptic membrane potential GO:0060079 14 12 0,000 6,499E-03 0,01365879 ! hippocampus development GO:0021766 12 12 0,000 6,499E-03 0,01365075 ! negative regulation of lipid metabolic process GO:0045833 13 12 0,000 6,499E-03 0,01364273 ! T cell selection GO:0045058 16 12 0,000 6,499E-03 0,01363471 ! cation:cation antiporter activity GO:0015491 12 12 0,000 6,499E-03 0,01362671 ! induction of apoptosis via death domain receptors GO:0008625 12 12 0,000 6,499E-03 0,01361871 ! T-tubule GO:0030315 13 12 0,000 6,499E-03 0,01361072 ! methionine metabolic process GO:0006555 13 12 0,000 6,499E-03 0,01360275 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 14 12 0,000 6,499E-03 0,01359478 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! peptide antigen binding GO:0042605 12 12 0,000 6,499E-03 0,01358682 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 6,499E-03 0,01357887 ! cell-cell junction assembly GO:0007043 12 12 0,000 6,499E-03 0,01357093 ! mitotic spindle organization GO:0007052 12 12 0,000 6,499E-03 0,01356299 ! fear response GO:0042596 12 12 0,000 6,499E-03 0,01355507 ! negative regulation of mitotic cell cycle GO:0045930 13 12 0,000 6,499E-03 0,01354716 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 6,499E-03 0,01353926 ! copper ion homeostasis GO:0055070 13 12 0,000 6,499E-03 0,01353136 ! lipoprotein receptor activity GO:0030228 12 12 0,000 6,499E-03 0,01352347 ! axon cargo transport GO:0008088 12 12 0,000 6,499E-03 0,0135156 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 13 12 0,000 6,499E-03 0,01350773 ! transcription elongation factor complex GO:0008023 13 12 0,000 6,499E-03 0,01349987 ! nuclear outer membrane GO:0005640 12 12 0,000 6,499E-03 0,01349203 ! beta-tubulin binding GO:0048487 12 12 0,000 6,499E-03 0,01348419 ! autonomic nervous system development GO:0048483 12 12 0,000 6,499E-03 0,01347635 ! positive regulation of interleukin-1 secretion GO:0050716 12 12 0,000 6,499E-03 0,01346853 GO:0050704|regulation of interleukin-1 secretion, ! exoribonuclease activity GO:0004532 12 12 0,000 6,499E-03 0,01346072 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! cofactor transport GO:0051181 12 12 0,000 6,499E-03 0,01345292 ! regulation of epidermis development GO:0045682 12 12 0,000 6,499E-03 0,01344512 ! protein-chromophore linkage GO:0018298 12 12 0,000 6,499E-03 0,01343734 ! cell killing GO:0001906 12 12 0,000 6,499E-03 0,01342956 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 12 0,000 6,499E-03 0,01342179 ! lymphocyte homeostasis GO:0002260 14 12 0,000 6,499E-03 0,01341404 ! regulation of fatty acid oxidation GO:0046320 13 12 0,000 6,499E-03 0,01340629 ! detection of bacterium GO:0016045 13 12 0,000 6,499E-03 0,01339855 ! positive regulation of neuron apoptosis GO:0043525 12 12 0,000 6,499E-03 0,01339082 ! dystrophin-associated glycoprotein complex GO:0016010 14 12 0,000 6,499E-03 0,01338309 ! internal side of plasma membrane GO:0009898 14 12 0,000 6,499E-03 0,01337538 ! RNA 3'-end processing GO:0031123 12 12 0,000 6,499E-03 0,01336767 ! developmental induction GO:0031128 13 12 0,000 6,499E-03 0,01335998 GO:0045168|cell-cell signaling involved in cell fate specification, ! fibrillar collagen GO:0005583 13 12 0,000 6,499E-03 0,01335229 ! positive regulation of calcium-mediated signaling GO:0050850 14 12 0,000 6,499E-03 0,01334461 ! inner ear receptor cell differentiation GO:0060113 13 12 0,000 6,499E-03 0,01333694 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 6,499E-03 0,01332928 ! very-long-chain fatty acid metabolic process GO:0000038 12 12 0,000 6,499E-03 0,01332163 ! negative regulation of cell projection organization GO:0031345 14 12 0,000 6,499E-03 0,01331399 ! thyroid gland development GO:0030878 12 12 0,000 6,499E-03 0,01330635 ! non-recombinational repair GO:0000726 12 12 0,000 6,499E-03 0,01329873 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 12 12 0,000 6,499E-03 0,01329111 ! lipid localization GO:0010876 12 12 0,000 6,499E-03 0,0132835 GO:0019915|lipid storage, ! regulation of glycolysis GO:0006110 12 12 0,000 6,499E-03 0,01327591 ! response to cAMP GO:0051591 12 12 0,000 6,499E-03 0,01326832 ! negative regulation of transcription factor import into nucleus GO:0042992 12 12 0,000 6,499E-03 0,01326073 ! T cell proliferation GO:0042098 17 12 0,000 6,499E-03 0,01325316 ! negative regulation of protein amino acid phosphorylation GO:0001933 16 12 0,000 6,499E-03 0,0132456 ! receptor signaling protein tyrosine kinase activity GO:0004716 13 12 0,000 6,499E-03 0,01323804 ! two-component signal transduction system (phosphorelay) GO:0000160 13 12 0,000 6,499E-03 0,01323049 ! peptide or protein amino-terminal blocking GO:0018409 13 12 0,000 6,499E-03 0,01322295 ! drug transport GO:0015893 12 12 0,000 6,499E-03 0,01321542 ! GTP-dependent protein binding GO:0030742 12 12 0,000 6,499E-03 0,0132079 ! regulation of interleukin-6 biosynthetic process GO:0045408 12 12 0,000 6,499E-03 0,01320039 ! T cell receptor complex GO:0042101 12 12 0,000 6,499E-03 0,01319288 ! membrane protein proteolysis GO:0033619 13 12 0,000 6,499E-03 0,01318539 GO:0006509|membrane protein ectodomain proteolysis, ! protein disulfide oxidoreductase activity GO:0015035 12 12 0,000 6,499E-03 0,0131779 ! histone acetyltransferase complex GO:0000123 13 12 0,000 6,499E-03 0,01317042 ! dendritic spine GO:0043197 12 12 0,000 6,499E-03 0,01316295 ! ATP-binding cassette (ABC) transporter complex GO:0043190 12 12 0,000 6,499E-03 0,01315549 ! alpha-beta T cell activation GO:0046631 13 12 0,000 6,499E-03 0,01314804 ! organic anion transmembrane transporter activity GO:0008514 13 12 0,000 6,499E-03 0,01314059 ! vasoconstriction GO:0042310 13 12 0,000 6,499E-03 0,01313315 ! DNA unwinding during replication GO:0006268 12 12 0,000 6,499E-03 0,01312573 ! cellular amino acid derivative catabolic process GO:0042219 16 12 0,000 6,499E-03 0,01311831 ! mRNA splice site selection GO:0006376 13 12 0,000 6,499E-03 0,01311089 ! phosphate transmembrane transporter activity GO:0015114 13 12 0,000 6,499E-03 0,01310349 ! trans-Golgi network transport vesicle membrane GO:0012510 15 12 0,000 6,499E-03 0,0130961 ! ubiquitin protein ligase binding GO:0031625 12 12 0,000 6,499E-03 0,01308871 ! monosaccharide transmembrane transporter activity GO:0015145 12 12 0,000 6,499E-03 0,01308133 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 12 12 0,000 6,499E-03 0,01307396 ! hexosaminidase activity GO:0015929 12 12 0,000 6,499E-03 0,0130666 ! diacylglycerol kinase activity GO:0004143 13 12 0,000 6,499E-03 0,01305925 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 6,499E-03 0,0130519 ! activation of NF-kappaB-inducing kinase activity GO:0007250 12 12 0,000 6,499E-03 0,01304457 ! protein kinase C binding GO:0005080 13 12 0,000 6,499E-03 0,01303724 ! catecholamine biosynthetic process GO:0042423 13 12 0,000 6,499E-03 0,01302992 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 15 12 0,000 6,499E-03 0,01302261 ! establishment or maintenance of apical/basal cell polarity GO:0035088 12 12 0,000 6,499E-03 0,0130153 ! L-fucose metabolic process GO:0042354 14 12 0,000 6,499E-03 0,01300801 ! acylglycerol O-acyltransferase activity GO:0016411 12 12 0,000 6,499E-03 0,01300072 ! C-acyltransferase activity GO:0016408 12 12 0,000 6,499E-03 0,01299344 ! steroid hydroxylase activity GO:0008395 12 12 0,000 6,499E-03 0,01298617 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 6,499E-03 0,01297891 ! calcium-activated potassium channel activity GO:0015269 14 12 0,000 6,499E-03 0,01297165 ! SWI/SNF-type complex GO:0070603 13 12 0,000 6,499E-03 0,0129644 GO:0016514|SWI/SNF complex, ! cilium part GO:0044441 12 12 0,000 6,499E-03 0,01295717 ! ER-associated protein catabolic process GO:0030433 13 13 0,000 7,038E-03 0,01402576 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 7,038E-03 0,01401794 ! superoxide anion generation GO:0042554 13 13 0,000 7,038E-03 0,01401013 ! pteridine and derivative biosynthetic process GO:0042559 14 13 0,000 7,038E-03 0,01400232 ! cis-Golgi network GO:0005801 14 13 0,000 7,038E-03 0,01399453 ! regulation of S phase GO:0033261 17 13 0,000 7,038E-03 0,01398674 ! regulation of chemokine production GO:0032642 13 13 0,000 7,038E-03 0,01397896 ! phospholipid catabolic process GO:0009395 14 13 0,000 7,038E-03 0,01397119 ! endothelial cell migration GO:0043542 13 13 0,000 7,038E-03 0,01396343 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 13 13 0,000 7,038E-03 0,01395567 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 7,038E-03 0,01394793 ! cartilage condensation GO:0001502 14 13 0,000 7,038E-03 0,01394019 ! organelle fusion GO:0048284 14 13 0,000 7,038E-03 0,01393247 ! positive regulation of lipid metabolic process GO:0045834 13 13 0,000 7,038E-03 0,01392475 ! pseudouridine synthesis GO:0001522 14 13 0,000 7,038E-03 0,01391704 ! negative regulation of gene expression, epigenetic GO:0045814 13 13 0,000 7,038E-03 0,01390934 ! regulation of interleukin-2 biosynthetic process GO:0045076 13 13 0,000 7,038E-03 0,01390164 ! negative regulation of proteolysis GO:0045861 13 13 0,000 7,038E-03 0,01389396 ! regulation of mRNA processing GO:0050684 13 13 0,000 7,038E-03 0,01388628 ! arginine metabolic process GO:0006525 13 13 0,000 7,038E-03 0,01387861 ! WW domain binding GO:0050699 14 13 0,000 7,038E-03 0,01387095 ! cholesterol binding GO:0015485 13 13 0,000 7,038E-03 0,0138633 ! negative regulation of microtubule depolymerization GO:0007026 15 13 0,000 7,038E-03 0,01385566 GO:0031114|regulation of microtubule depolymerization, ! Golgi organization GO:0007030 16 13 0,000 7,038E-03 0,01384803 ! negative regulation of endothelial cell migration GO:0010596 13 13 0,000 7,038E-03 0,0138404 ! integral to peroxisomal membrane GO:0005779 13 13 0,000 7,038E-03 0,01383278 GO:0031231|intrinsic to peroxisomal membrane, ! integral to membrane of membrane fraction GO:0000299 14 13 0,000 7,038E-03 0,01382518 ! regulation of heart rate GO:0002027 14 13 0,000 7,038E-03 0,01381758 ! positive regulation of carbohydrate metabolic process GO:0045913 14 13 0,000 7,038E-03 0,01380998 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 14 13 0,000 7,038E-03 0,0138024 ! negative regulation of immune response GO:0050777 17 13 0,000 7,038E-03 0,01379482 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 13 0,000 7,038E-03 0,01378726 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 7,038E-03 0,0137797 ! response to estradiol stimulus GO:0032355 14 13 0,000 7,038E-03 0,01377215 ! anaphase-promoting complex GO:0005680 13 13 0,000 7,038E-03 0,01376461 ! nucleotide diphosphatase activity GO:0004551 13 13 0,000 7,038E-03 0,01375707 ! NADP metabolic process GO:0006739 13 13 0,000 7,038E-03 0,01374955 ! regulation of erythrocyte differentiation GO:0045646 13 13 0,000 7,038E-03 0,01374203 ! intestinal absorption GO:0050892 13 13 0,000 7,038E-03 0,01373452 ! eukaryotic cell surface binding GO:0043499 14 13 0,000 7,038E-03 0,01372702 ! digestive tract morphogenesis GO:0048546 13 13 0,000 7,038E-03 0,01371953 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 14 13 0,000 7,038E-03 0,01371204 ! regulation of cellular carbohydrate catabolic process GO:0043471 14 13 0,000 7,038E-03 0,01370456 GO:0043470|regulation of carbohydrate catabolic process, ! tropomyosin binding GO:0005523 13 13 0,000 7,038E-03 0,0136971 ! carbon-sulfur lyase activity GO:0016846 13 13 0,000 7,038E-03 0,01368964 ! embryonic placenta development GO:0001892 13 13 0,000 7,038E-03 0,01368218 ! positive regulation of protein polymerization GO:0032273 13 13 0,000 7,038E-03 0,01367474 ! insulin secretion GO:0030073 13 13 0,000 7,038E-03 0,0136673 ! positive regulation of cellular catabolic process GO:0031331 14 13 0,000 7,038E-03 0,01365987 ! G1 phase of mitotic cell cycle GO:0000080 13 13 0,000 7,038E-03 0,01365246 ! replisome GO:0030894 14 13 0,000 7,038E-03 0,01364504 GO:0043601|nuclear replisome, ! regulation of nitric-oxide synthase activity GO:0050999 13 13 0,000 7,038E-03 0,01363764 ! double-strand break repair via homologous recombination GO:0000724 13 13 0,000 7,038E-03 0,01363024 GO:0000725|recombinational repair, ! copper ion transport GO:0006825 13 13 0,000 7,038E-03 0,01362286 ! regulation of cell-cell adhesion GO:0022407 13 13 0,000 7,038E-03 0,01361548 ! forelimb morphogenesis GO:0035136 13 13 0,000 7,038E-03 0,0136081 ! mating GO:0007618 13 13 0,000 7,038E-03 0,01360074 ! phosphatidylinositol phosphate kinase activity GO:0016307 14 13 0,000 7,038E-03 0,01359339 ! MAP kinase activity GO:0004707 14 13 0,000 7,038E-03 0,01358604 ! cytokine biosynthetic process GO:0042089 13 13 0,000 7,038E-03 0,0135787 ! ventral spinal cord development GO:0021517 13 13 0,000 7,038E-03 0,01357137 ! prenyltransferase activity GO:0004659 14 13 0,000 7,038E-03 0,01356404 ! platelet-derived growth factor receptor signaling pathway GO:0048008 15 13 0,000 7,038E-03 0,01355673 ! regulation of skeletal muscle fiber development GO:0048742 13 13 0,000 7,038E-03 0,01354942 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 15 13 0,000 7,038E-03 0,01354212 ! protein kinase C activity GO:0004697 15 13 0,000 7,038E-03 0,01353482 ! water transporter activity GO:0005372 13 13 0,000 7,038E-03 0,01352754 ! exocrine system development GO:0035272 14 13 0,000 7,038E-03 0,01352026 ! dicarboxylic acid transmembrane transporter activity GO:0005310 13 13 0,000 7,038E-03 0,01351299 ! monoamine transport GO:0015844 13 13 0,000 7,038E-03 0,01350573 ! CoA hydrolase activity GO:0016289 13 13 0,000 7,038E-03 0,01349848 ! embryo implantation GO:0007566 13 13 0,000 7,038E-03 0,01349123 ! G1/S transition checkpoint GO:0031575 13 13 0,000 7,038E-03 0,013484 ! positive regulation of alpha-beta T cell differentiation GO:0046638 13 13 0,000 7,038E-03 0,01347677 ! immunoglobulin binding GO:0019865 13 13 0,000 7,038E-03 0,01346954 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 7,038E-03 0,01346233 ! anchored to plasma membrane GO:0046658 14 13 0,000 7,038E-03 0,01345512 ! MHC class I protein binding GO:0042288 13 13 0,000 7,038E-03 0,01344792 ! histone deacetylation GO:0016575 13 13 0,000 7,038E-03 0,01344073 ! calcium channel regulator activity GO:0005246 14 13 0,000 7,038E-03 0,01343355 ! neuroblast proliferation GO:0007405 13 13 0,000 7,038E-03 0,01342637 ! peptide biosynthetic process GO:0043043 14 13 0,000 7,038E-03 0,0134192 ! response to gamma radiation GO:0010332 13 13 0,000 7,038E-03 0,01341204 ! sarcomere organization GO:0045214 13 13 0,000 7,038E-03 0,01340489 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 15 13 0,000 7,038E-03 0,01339775 ! cAMP binding GO:0030552 13 13 0,000 7,038E-03 0,01339061 ! fucosyltransferase activity GO:0008417 14 13 0,000 7,038E-03 0,01338348 ! cilium assembly GO:0042384 13 13 0,000 7,038E-03 0,01337635 ! negative regulation of leukocyte proliferation GO:0070664 13 13 0,000 7,038E-03 0,01336924 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! bacterial binding GO:0008367 13 13 0,000 7,038E-03 0,01336213 ! regulation of NF-kappaB import into nucleus GO:0042345 13 13 0,000 7,038E-03 0,01335503 ! acrosome reaction GO:0007340 13 13 0,000 7,038E-03 0,01334794 ! microtubule-based flagellum GO:0009434 13 13 0,000 7,038E-03 0,01334085 ! nucleolar part GO:0044452 13 13 0,000 7,038E-03 0,01333378 ! axoneme part GO:0044447 13 13 0,000 7,038E-03 0,01332671 ! tRNA modification GO:0006400 14 14 0,000 7,578E-03 0,01434083 ! positive regulation of blood pressure GO:0045777 15 14 0,000 7,578E-03 0,01433323 ! transferase activity, transferring amino-acyl groups GO:0016755 14 14 0,000 7,578E-03 0,01432564 ! negative regulation of bone remodeling GO:0046851 14 14 0,000 7,578E-03 0,01431806 ! 2'-deoxyribonucleotide metabolic process GO:0009394 15 14 0,000 7,578E-03 0,01431049 GO:0019692|deoxyribose phosphate metabolic process, ! transcription from RNA polymerase III promoter GO:0006383 14 14 0,000 7,578E-03 0,01430293 ! guanylate kinase activity GO:0004385 16 14 0,000 7,578E-03 0,01429537 ! striated muscle thin filament GO:0005865 15 14 0,000 7,578E-03 0,01428782 ! patterning of blood vessels GO:0001569 14 14 0,000 7,578E-03 0,01428028 ! mechanoreceptor differentiation GO:0042490 15 14 0,000 7,578E-03 0,01427275 ! palate development GO:0060021 15 14 0,000 7,578E-03 0,01426523 ! centrosome cycle GO:0007098 14 14 0,000 7,578E-03 0,01425771 ! regulation of defense response to virus GO:0050688 14 14 0,000 7,578E-03 0,01425021 ! cAMP-dependent protein kinase regulator activity GO:0008603 14 14 0,000 7,578E-03 0,01424271 ! ephrin receptor activity GO:0005003 16 14 0,000 7,578E-03 0,01423521 ! protein polyubiquitination GO:0000209 15 14 0,000 7,578E-03 0,01422773 ! glycine metabolic process GO:0006544 15 14 0,000 7,578E-03 0,01422025 ! plasma membrane organization GO:0007009 14 14 0,000 7,578E-03 0,01421278 ! tyrosine metabolic process GO:0006570 16 14 0,000 7,578E-03 0,01420532 ! response to retinoic acid GO:0032526 14 14 0,000 7,578E-03 0,01419787 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 16 14 0,000 7,578E-03 0,01419042 ! lysosomal transport GO:0007041 14 14 0,000 7,578E-03 0,01418299 ! rough endoplasmic reticulum GO:0005791 14 14 0,000 7,578E-03 0,01417556 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 14 14 0,000 7,578E-03 0,01416814 ! regulation of the force of heart contraction GO:0002026 15 14 0,000 7,578E-03 0,01416072 ! bone mineralization GO:0030282 14 14 0,000 7,578E-03 0,01415332 ! protein kinase activator activity GO:0030295 14 14 0,000 7,578E-03 0,01414592 ! NLS-bearing substrate import into nucleus GO:0006607 15 14 0,000 7,578E-03 0,01413853 ! cerebellum development GO:0021549 15 14 0,000 7,578E-03 0,01413114 ! G1 phase GO:0051318 14 14 0,000 7,578E-03 0,01412377 ! negative regulation of blood coagulation GO:0030195 16 14 0,000 7,578E-03 0,0141164 ! negative regulation of protein secretion GO:0050709 14 14 0,000 7,578E-03 0,01410904 ! water homeostasis GO:0030104 14 14 0,000 7,578E-03 0,01410169 ! peptide hormone binding GO:0017046 14 14 0,000 7,578E-03 0,01409434 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 7,578E-03 0,01408701 ! glutamine family amino acid biosynthetic process GO:0009084 15 14 0,000 7,578E-03 0,01407968 ! regulation of ATPase activity GO:0043462 15 14 0,000 7,578E-03 0,01407236 ! racemase and epimerase activity GO:0016854 14 14 0,000 7,578E-03 0,01406504 ! regulation of leukocyte mediated cytotoxicity GO:0001910 18 14 0,000 7,578E-03 0,01405774 ! positive regulation of calcium ion transport GO:0051928 17 14 0,000 7,578E-03 0,01405044 ! regulation of blood vessel endothelial cell migration GO:0043535 14 14 0,000 7,578E-03 0,01404314 ! regulation of calcium-mediated signaling GO:0050848 16 14 0,000 7,578E-03 0,01403586 ! positive regulation of synaptic transmission GO:0050806 14 14 0,000 7,578E-03 0,01402858 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 16 14 0,000 7,578E-03 0,01402132 ! lactation GO:0007595 15 14 0,000 7,578E-03 0,01401405 ! reproductive cellular process GO:0048610 14 14 0,000 7,578E-03 0,0140068 ! positive regulation of cell killing GO:0031343 18 14 0,000 7,578E-03 0,01399956 ! sulfur amino acid biosynthetic process GO:0000097 15 14 0,000 7,578E-03 0,01399232 ! dicarboxylic acid transport GO:0006835 14 14 0,000 7,578E-03 0,01398509 ! regulation of B cell proliferation GO:0030888 18 14 0,000 7,578E-03 0,01397786 ! inorganic anion exchanger activity GO:0005452 15 14 0,000 7,578E-03 0,01397065 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 15 14 0,000 7,578E-03 0,01396344 ! negative regulation of cytokine biosynthetic process GO:0042036 14 14 0,000 7,578E-03 0,01395624 ! negative regulation of ion transport GO:0043271 14 14 0,000 7,578E-03 0,01394904 ! retinoic acid receptor binding GO:0042974 14 14 0,000 7,578E-03 0,01394185 ! startle response GO:0001964 14 14 0,000 7,578E-03 0,01393468 ! 2 iron, 2 sulfur cluster binding GO:0051537 14 14 0,000 7,578E-03 0,0139275 ! activation of MAPKK activity GO:0000186 15 14 0,000 7,578E-03 0,01392034 ! cytokine metabolic process GO:0042107 14 14 0,000 7,578E-03 0,01391318 ! organic alcohol transport GO:0015850 15 14 0,000 7,578E-03 0,01390603 ! preassembly of GPI anchor in ER membrane GO:0016254 15 14 0,000 7,578E-03 0,01389889 ! calcium ion transmembrane transporter activity GO:0015085 16 14 0,000 7,578E-03 0,01389176 ! eukaryotic translation initiation factor 4F complex GO:0016281 14 14 0,000 7,578E-03 0,01388463 ! nucleoside kinase activity GO:0019206 17 14 0,000 7,578E-03 0,01387751 ! L-amino acid transport GO:0015807 14 14 0,000 7,578E-03 0,01387039 ! microfilament motor activity GO:0000146 14 14 0,000 7,578E-03 0,01386329 ! stem cell development GO:0048864 14 14 0,000 7,578E-03 0,01385619 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 15 14 0,000 7,578E-03 0,0138491 ! DNA replication initiation GO:0006270 14 14 0,000 7,578E-03 0,01384202 ! T cell differentiation in the thymus GO:0033077 18 14 0,000 7,578E-03 0,01383494 ! regulation of cellular pH GO:0030641 14 14 0,000 7,578E-03 0,01382787 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 7,578E-03 0,01382081 ! calcium activated cation channel activity GO:0005227 16 14 0,000 7,578E-03 0,01381375 ! sulfuric ester hydrolase activity GO:0008484 15 14 0,000 7,578E-03 0,0138067 ! serotonin receptor activity GO:0004993 14 14 0,000 7,578E-03 0,01379966 ! positive regulation of bone mineralization GO:0030501 15 14 0,000 7,578E-03 0,01379263 ! synaptic transmission, cholinergic GO:0007271 15 14 0,000 7,578E-03 0,0137856 ! dopamine metabolic process GO:0042417 17 14 0,000 7,578E-03 0,01377858 ! cAMP biosynthetic process GO:0006171 14 14 0,000 7,578E-03 0,01377157 ! ion gated channel activity GO:0022839 16 14 0,000 7,578E-03 0,01376457 ! male genitalia development GO:0030539 14 14 0,000 7,578E-03 0,01375757 ! regulation of axon extension GO:0030516 15 14 0,000 7,578E-03 0,01375058 ! regulation of BMP signaling pathway GO:0030510 14 14 0,000 7,578E-03 0,0137436 ! estrogen receptor signaling pathway GO:0030520 14 14 0,000 7,578E-03 0,01373662 ! interleukin-1 receptor binding GO:0005149 14 14 0,000 7,578E-03 0,01372965 ! defense response to virus GO:0051607 19 14 0,000 7,578E-03 0,01372269 ! cadherin binding GO:0045296 16 14 0,000 7,578E-03 0,01371573 ! negative regulation of hormone secretion GO:0046888 16 15 0,000 8,117E-03 0,0146845 ! nuclear replication fork GO:0043596 16 15 0,000 8,117E-03 0,01467706 ! phosphoinositide phosphorylation GO:0046854 16 15 0,000 8,117E-03 0,01466963 GO:0046834|lipid phosphorylation, ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 8,117E-03 0,01466221 ! cardiac muscle contraction GO:0060048 16 15 0,000 8,117E-03 0,0146548 ! polysome GO:0005844 16 15 0,000 8,117E-03 0,01464739 ! mitotic chromosome condensation GO:0007076 15 15 0,000 8,117E-03 0,01464 ! regulation of viral genome replication GO:0045069 15 15 0,000 8,117E-03 0,01463261 ! regulation of survival gene product expression GO:0045884 15 15 0,000 8,117E-03 0,01462522 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 15 0,000 8,117E-03 0,01461785 ! glycoprotein catabolic process GO:0006516 15 15 0,000 8,117E-03 0,01461048 ! DNA duplex unwinding GO:0032508 15 15 0,000 8,117E-03 0,01460312 GO:0032392|DNA geometric change, ! glutamine metabolic process GO:0006541 16 15 0,000 8,117E-03 0,01459577 ! proton-transporting V-type ATPase complex GO:0033176 15 15 0,000 8,117E-03 0,01458842 ! response to vitamin A GO:0033189 15 15 0,000 8,117E-03 0,01458108 ! protease binding GO:0002020 16 15 0,000 8,117E-03 0,01457375 ! regulation of ion transmembrane transporter activity GO:0032412 15 15 0,000 8,117E-03 0,01456643 ! actin filament bundle formation GO:0051017 15 15 0,000 8,117E-03 0,01455911 ! calcium ion-dependent exocytosis GO:0017156 15 15 0,000 8,117E-03 0,0145518 ! purine nucleoside monophosphate metabolic process GO:0009126 16 15 0,000 8,117E-03 0,0145445 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 15 15 0,000 8,117E-03 0,01453721 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 8,117E-03 0,01452992 ! positive regulation of biomineral formation GO:0070169 16 15 0,000 8,117E-03 0,01452264 ! positive regulation of oxidoreductase activity GO:0051353 15 15 0,000 8,117E-03 0,01451537 ! filopodium GO:0030175 15 15 0,000 8,117E-03 0,0145081 ! negative regulation of inflammatory response GO:0050728 15 15 0,000 8,117E-03 0,01450085 ! positive regulation of transmission of nerve impulse GO:0051971 15 15 0,000 8,117E-03 0,0144936 ! branched chain family amino acid metabolic process GO:0009081 15 15 0,000 8,117E-03 0,01448635 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 8,117E-03 0,01447912 ! heme biosynthetic process GO:0006783 15 15 0,000 8,117E-03 0,01447189 ! SMAD binding GO:0046332 16 15 0,000 8,117E-03 0,01446467 ! nerve development GO:0021675 16 15 0,000 8,117E-03 0,01445745 ! epithelial to mesenchymal transition GO:0001837 16 15 0,000 8,117E-03 0,01445025 ! mannose binding GO:0005537 15 15 0,000 8,117E-03 0,01444305 ! phosphoprotein binding GO:0051219 17 15 0,000 8,117E-03 0,01443585 ! mismatched DNA binding GO:0030983 15 15 0,000 8,117E-03 0,01442867 ! antigen receptor-mediated signaling pathway GO:0050851 21 15 0,000 8,117E-03 0,01442149 ! regulation of skeletal muscle tissue development GO:0048641 15 15 0,000 8,117E-03 0,01441432 ! synaptonemal complex GO:0000795 15 15 0,000 8,117E-03 0,01440715 ! N-terminal protein amino acid modification GO:0031365 16 15 0,000 8,117E-03 0,0144 ! positive regulation of protein complex assembly GO:0031334 15 15 0,000 8,117E-03 0,01439285 ! water transport GO:0006833 15 15 0,000 8,117E-03 0,0143857 GO:0042044|fluid transport, ! phosphatidylinositol metabolic process GO:0046488 16 15 0,000 8,117E-03 0,01437857 ! viral genome replication GO:0019079 15 15 0,000 8,117E-03 0,01437144 ! phosphatidylcholine metabolic process GO:0046470 17 15 0,000 8,117E-03 0,01436432 ! inositol metabolic process GO:0006020 15 15 0,000 8,117E-03 0,0143572 ! sulfate transport GO:0008272 15 15 0,000 8,117E-03 0,0143501 ! protein-lipid complex GO:0032994 15 15 0,000 8,117E-03 0,014343 GO:0034358|plasma lipoprotein particle, ! positive regulation of ion transport GO:0043270 18 15 0,000 8,117E-03 0,0143359 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 15 15 0,000 8,117E-03 0,01432882 ! heart looping GO:0001947 15 15 0,000 8,117E-03 0,01432174 ! isoprenoid biosynthetic process GO:0008299 16 15 0,000 8,117E-03 0,01431466 ! protein histidine kinase activity GO:0004673 16 15 0,000 8,117E-03 0,0143076 GO:0000155|two-component sensor activity, ! cardiac muscle tissue development GO:0048738 15 15 0,000 8,117E-03 0,01430054 ! regulation of striated muscle contraction GO:0006942 16 15 0,000 8,117E-03 0,01429349 ! response to osmotic stress GO:0006970 16 15 0,000 8,117E-03 0,01428644 ! fructose metabolic process GO:0006000 15 15 0,000 8,117E-03 0,01427941 ! ubiquitin binding GO:0043130 15 15 0,000 8,117E-03 0,01427238 ! vesicle coating GO:0006901 16 15 0,000 8,117E-03 0,01426535 ! DNA integration GO:0015074 16 15 0,000 8,117E-03 0,01425833 ! alcohol binding GO:0043178 16 15 0,000 8,117E-03 0,01425132 ! disulfide oxidoreductase activity GO:0015036 15 15 0,000 8,117E-03 0,01424432 ! intermediate filament cytoskeleton organization GO:0045104 16 15 0,000 8,117E-03 0,01423733 ! regulation of vasodilation GO:0042312 15 15 0,000 8,117E-03 0,01423034 ! genitalia development GO:0048806 15 15 0,000 8,117E-03 0,01422335 ! structural constituent of eye lens GO:0005212 15 15 0,000 8,117E-03 0,01421638 ! regulation of monooxygenase activity GO:0032768 15 15 0,000 8,117E-03 0,01420941 ! voltage-gated sodium channel activity GO:0005248 17 15 0,000 8,117E-03 0,01420245 ! ribonucleoprotein binding GO:0043021 16 15 0,000 8,117E-03 0,01419549 ! proton-transporting ATP synthase complex GO:0045259 15 15 0,000 8,117E-03 0,01418854 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 15 15 0,000 8,117E-03 0,0141816 ! regulation of immunoglobulin production GO:0002637 19 15 0,000 8,117E-03 0,01417467 ! retinoic acid receptor activity GO:0003708 15 15 0,000 8,117E-03 0,01416774 ! receptor activator activity GO:0030546 15 15 0,000 8,117E-03 0,01416082 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 15 15 0,000 8,117E-03 0,0141539 ! protein transmembrane transporter activity GO:0008320 15 15 0,000 8,117E-03 0,014147 ! histone binding GO:0042393 15 15 0,000 8,117E-03 0,01414009 ! phosphoinositide 3-kinase activity GO:0035004 16 15 0,000 8,117E-03 0,0141332 ! sialyltransferase activity GO:0008373 15 15 0,000 8,117E-03 0,01412631 ! platelet-derived growth factor receptor binding GO:0005161 16 15 0,000 8,117E-03 0,01411943 ! drug transporter activity GO:0015238 15 15 0,000 8,117E-03 0,01411256 ! negative regulation of homeostatic process GO:0032845 15 15 0,000 8,117E-03 0,01410569 ! phosphoinositide 3-kinase complex GO:0005942 16 15 0,000 8,117E-03 0,01409883 ! binding of sperm to zona pellucida GO:0007339 16 15 0,000 8,117E-03 0,01409198 ! peptide hormone processing GO:0016486 17 15 0,000 8,117E-03 0,01408513 ! aldo-keto reductase activity GO:0004033 15 15 0,000 8,117E-03 0,01407829 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 8,117E-03 0,01407145 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 16 16 0,000 8,656E-03 0,01499871 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 8,656E-03 0,01499143 ! positive regulation of hormone secretion GO:0046887 17 16 0,000 8,656E-03 0,01498416 ! protein amino acid ADP-ribosylation GO:0006471 18 16 0,000 8,656E-03 0,0149769 ! response to vitamin GO:0033273 16 16 0,000 8,656E-03 0,01496965 ! gene silencing by RNA GO:0031047 16 16 0,000 8,656E-03 0,01496241 ! regulation of postsynaptic membrane potential GO:0060078 18 16 0,000 8,656E-03 0,01495517 ! kinesin complex GO:0005871 16 16 0,000 8,656E-03 0,01494794 ! cornified envelope GO:0001533 18 16 0,000 8,656E-03 0,01494071 ! regulation of transmembrane transporter activity GO:0022898 16 16 0,000 8,656E-03 0,01493349 GO:0032409|regulation of transporter activity, ! negative regulation of epithelial cell proliferation GO:0050680 17 16 0,000 8,656E-03 0,01492628 ! pyrimidine ribonucleotide metabolic process GO:0009218 18 16 0,000 8,656E-03 0,01491908 ! pituitary gland development GO:0021983 16 16 0,000 8,656E-03 0,01491188 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 18 16 0,000 8,656E-03 0,01490469 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 19 16 0,000 8,656E-03 0,01489751 ! cell-substrate junction assembly GO:0007044 18 16 0,000 8,656E-03 0,01489033 ! peptidyl-serine phosphorylation GO:0018105 16 16 0,000 8,656E-03 0,01488316 ! branching involved in ureteric bud morphogenesis GO:0001658 16 16 0,000 8,656E-03 0,014876 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 16 16 0,000 8,656E-03 0,01486885 ! nucleobase metabolic process GO:0009112 19 16 0,000 8,656E-03 0,0148617 ! beta-catenin binding GO:0008013 17 16 0,000 8,656E-03 0,01485456 ! regulation of steroid metabolic process GO:0019218 17 16 0,000 8,656E-03 0,01484742 ! neuron recognition GO:0008038 17 16 0,000 8,656E-03 0,01484029 ! oogenesis GO:0048477 19 16 0,000 8,656E-03 0,01483317 ! low-density lipoprotein binding GO:0030169 17 16 0,000 8,656E-03 0,01482606 ! clathrin vesicle coat GO:0030125 19 16 0,000 8,656E-03 0,01481895 ! COPI-coated vesicle GO:0030137 16 16 0,000 8,656E-03 0,01481185 ! sphingolipid biosynthetic process GO:0030148 16 16 0,000 8,656E-03 0,01480476 ! biomineral formation GO:0031214 16 16 0,000 8,656E-03 0,01479767 ! vitamin transport GO:0051180 16 16 0,000 8,656E-03 0,01479059 ! folic acid and derivative metabolic process GO:0006760 16 16 0,000 8,656E-03 0,01478352 ! organic cation transport GO:0015695 16 16 0,000 8,656E-03 0,01477645 ! proximal/distal pattern formation GO:0009954 16 16 0,000 8,656E-03 0,01476939 ! regulation of glucose import GO:0046324 17 16 0,000 8,656E-03 0,01476234 GO:0010827|regulation of glucose transport, ! aromatic compound biosynthetic process GO:0019438 17 16 0,000 8,656E-03 0,01475529 ! aromatic compound catabolic process GO:0019439 18 16 0,000 8,656E-03 0,01474825 ! negative regulation of coagulation GO:0050819 18 16 0,000 8,656E-03 0,01474122 ! tRNA binding GO:0000049 16 16 0,000 8,656E-03 0,01473419 ! regulation of cell killing GO:0031341 20 16 0,000 8,656E-03 0,01472717 ! negative regulation of defense response GO:0031348 16 16 0,000 8,656E-03 0,01472016 ! regulation of neuronal synaptic plasticity GO:0048168 16 16 0,000 8,656E-03 0,01471315 ! hindlimb morphogenesis GO:0035137 16 16 0,000 8,656E-03 0,01470615 ! bile acid metabolic process GO:0008206 16 16 0,000 8,656E-03 0,01469916 ! axis specification GO:0009798 16 16 0,000 8,656E-03 0,01469217 ! adult walking behavior GO:0007628 17 16 0,000 8,656E-03 0,01468519 ! C-C chemokine binding GO:0019957 16 16 0,000 8,656E-03 0,01467822 GO:0016493|C-C chemokine receptor activity, ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 18 16 0,000 8,656E-03 0,01467125 ! protein phosphatase binding GO:0019903 17 16 0,000 8,656E-03 0,01466429 ! epidermis morphogenesis GO:0048730 16 16 0,000 8,656E-03 0,01465734 ! acyl-CoA dehydrogenase activity GO:0003995 16 16 0,000 8,656E-03 0,01465039 ! complement activation, alternative pathway GO:0006957 16 16 0,000 8,656E-03 0,01464345 ! SH2 domain binding GO:0042169 19 16 0,000 8,656E-03 0,01463652 ! UDP-galactosyltransferase activity GO:0035250 17 16 0,000 8,656E-03 0,01462959 ! RNA methyltransferase activity GO:0008173 16 16 0,000 8,656E-03 0,01462267 ! neutral amino acid transport GO:0015804 16 16 0,000 8,656E-03 0,01461576 ! glucuronosyltransferase activity GO:0015020 17 16 0,000 8,656E-03 0,01460885 ! regulation of alpha-beta T cell differentiation GO:0046637 16 16 0,000 8,656E-03 0,01460195 ! cellular pigmentation GO:0033059 16 16 0,000 8,656E-03 0,01459506 ! mannosidase activity GO:0015923 19 16 0,000 8,656E-03 0,01458817 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 16 16 0,000 8,656E-03 0,01458129 ! negative regulation of tissue remodeling GO:0034104 16 16 0,000 8,656E-03 0,01457441 ! positive regulation of neurological system process GO:0031646 16 16 0,000 8,656E-03 0,01456755 ! neuromuscular synaptic transmission GO:0007274 16 16 0,000 8,656E-03 0,01456068 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 8,656E-03 0,01455383 ! sperm-egg recognition GO:0035036 17 16 0,000 8,656E-03 0,01454698 ! axoneme GO:0005930 16 16 0,000 8,656E-03 0,01454014 ! anion exchanger activity GO:0015380 18 17 0,000 9,195E-03 0,01543797 ! neuron maturation GO:0042551 18 17 0,000 9,195E-03 0,01543071 ! metencephalon development GO:0022037 18 17 0,000 9,195E-03 0,01542346 ! regulation of lipid biosynthetic process GO:0046890 18 17 0,000 9,195E-03 0,01541622 ! reciprocal meiotic recombination GO:0007131 17 17 0,000 9,195E-03 0,01540899 ! hemoglobin complex GO:0005833 18 17 0,000 9,195E-03 0,01540176 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 17 17 0,000 9,195E-03 0,01539454 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 17 17 0,000 9,195E-03 0,01538733 ! protein amino acid deacetylation GO:0006476 17 17 0,000 9,195E-03 0,01538012 ! protein amino acid acetylation GO:0006473 19 17 0,000 9,195E-03 0,01537292 ! positive regulation of nucleocytoplasmic transport GO:0046824 18 17 0,000 9,195E-03 0,01536572 ! regulation of neurotransmitter secretion GO:0046928 18 17 0,000 9,195E-03 0,01535854 ! striated muscle thick filament GO:0005863 19 17 0,000 9,195E-03 0,01535136 GO:0032982|myosin filament, ! gamma-aminobutyric acid signaling pathway GO:0007214 17 17 0,000 9,195E-03 0,01534418 ! regulation of muscle cell differentiation GO:0051147 17 17 0,000 9,195E-03 0,01533702 ! pancreas development GO:0031016 17 17 0,000 9,195E-03 0,01532986 ! acetylcholine receptor activity GO:0015464 17 17 0,000 9,195E-03 0,0153227 ! nuclear heterochromatin GO:0005720 18 17 0,000 9,195E-03 0,01531556 ! calcium-dependent protein binding GO:0048306 19 17 0,000 9,195E-03 0,01530842 ! cerebral cortex development GO:0021987 17 17 0,000 9,195E-03 0,01530128 ! cellular response to starvation GO:0009267 18 17 0,000 9,195E-03 0,01529416 ! signal sequence binding GO:0005048 17 17 0,000 9,195E-03 0,01528704 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 17 17 0,000 9,195E-03 0,01527992 ! cellular macromolecular complex disassembly GO:0034623 18 17 0,000 9,195E-03 0,01527282 ! transforming growth factor beta receptor activity GO:0005024 17 17 0,000 9,195E-03 0,01526572 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 9,195E-03 0,01525862 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 17 17 0,000 9,195E-03 0,01525153 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 17 0,000 9,195E-03 0,01524445 ! actin filament bundle GO:0032432 17 17 0,000 9,195E-03 0,01523738 GO:0001725|stress fiber, ! small nucleolar ribonucleoprotein complex GO:0005732 17 17 0,000 9,195E-03 0,01523031 ! response to lipopolysaccharide GO:0032496 17 17 0,000 9,195E-03 0,01522325 ! plasma membrane fusion GO:0045026 18 17 0,000 9,195E-03 0,0152162 ! regulation of protein binding GO:0043393 18 17 0,000 9,195E-03 0,01520915 ! recycling endosome GO:0055037 18 17 0,000 9,195E-03 0,01520211 ! prostaglandin metabolic process GO:0006693 18 17 0,000 9,195E-03 0,01519507 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 19 17 0,000 9,195E-03 0,01518805 ! regulation of immunoglobulin mediated immune response GO:0002889 21 17 0,000 9,195E-03 0,01518102 GO:0002712|regulation of B cell mediated immunity, ! receptor signaling complex scaffold activity GO:0030159 17 17 0,000 9,195E-03 0,01517401 ! positive regulation of cytokine secretion GO:0050715 17 17 0,000 9,195E-03 0,015167 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 17 0,000 9,195E-03 0,01516 ! endodeoxyribonuclease activity GO:0004520 17 17 0,000 9,195E-03 0,015153 ! sphingolipid catabolic process GO:0030149 18 17 0,000 9,195E-03 0,01514601 ! steroid catabolic process GO:0006706 17 17 0,000 9,195E-03 0,01513903 ! oxygen transport GO:0015671 18 17 0,000 9,195E-03 0,01513205 GO:0005344|oxygen transporter activity, ! phosphatidylinositol binding GO:0005545 19 17 0,000 9,195E-03 0,01512508 ! hyaluronic acid binding GO:0005540 17 17 0,000 9,195E-03 0,01511812 ! negative regulation of T cell activation GO:0050868 17 17 0,000 9,195E-03 0,01511116 ! regulation of glucose metabolic process GO:0010906 17 17 0,000 9,195E-03 0,01510421 ! G2/M transition of mitotic cell cycle GO:0000086 17 17 0,000 9,195E-03 0,01509727 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 17 17 0,000 9,195E-03 0,01509033 ! glycosaminoglycan biosynthetic process GO:0006024 17 17 0,000 9,195E-03 0,0150834 ! MAP kinase kinase kinase activity GO:0004709 18 17 0,000 9,195E-03 0,01507647 ! L-ascorbic acid binding GO:0031418 17 17 0,000 9,195E-03 0,01506955 ! negative regulation of endothelial cell proliferation GO:0001937 17 17 0,000 9,195E-03 0,01506264 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 18 17 0,000 9,195E-03 0,01505573 ! photoreceptor cell maintenance GO:0045494 17 17 0,000 9,195E-03 0,01504883 ! calmodulin-dependent protein kinase activity GO:0004683 19 17 0,000 9,195E-03 0,01504194 ! fucose metabolic process GO:0006004 19 17 0,000 9,195E-03 0,01503505 ! D-ribose metabolic process GO:0006014 18 17 0,000 9,195E-03 0,01502817 ! membrane budding GO:0006900 18 17 0,000 9,195E-03 0,0150213 ! AMP binding GO:0016208 17 17 0,000 9,195E-03 0,01501443 ! nuclear ubiquitin ligase complex GO:0000152 17 17 0,000 9,195E-03 0,01500757 ! body fluid secretion GO:0007589 18 17 0,000 9,195E-03 0,01500071 ! response to fungus GO:0009620 17 17 0,000 9,195E-03 0,01499386 ! positive regulation of alpha-beta T cell activation GO:0046635 21 17 0,000 9,195E-03 0,01498702 ! intermediate filament-based process GO:0045103 18 17 0,000 9,195E-03 0,01498018 ! rRNA binding GO:0019843 17 17 0,000 9,195E-03 0,01497335 ! nucleotide-excision repair, DNA gap filling GO:0006297 18 17 0,000 9,195E-03 0,01496652 ! regulation of interleukin-2 production GO:0032663 17 17 0,000 9,195E-03 0,01495971 ! voltage-gated chloride channel activity GO:0005247 17 17 0,000 9,195E-03 0,01495289 ! DNA fragmentation involved in apoptosis GO:0006309 17 17 0,000 9,195E-03 0,01494609 ! neutrophil chemotaxis GO:0030593 18 17 0,000 9,195E-03 0,01493929 ! long-chain fatty acid transport GO:0015909 17 17 0,000 9,195E-03 0,01493249 ! tissue regeneration GO:0042246 17 17 0,000 9,195E-03 0,01492571 ! detection of biotic stimulus GO:0009595 18 17 0,000 9,195E-03 0,01491892 ! muscle maintenance GO:0046716 18 17 0,000 9,195E-03 0,01491215 ! cell-cell junction organization GO:0045216 17 17 0,000 9,195E-03 0,01490538 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 17 17 0,000 9,195E-03 0,01489862 ! somatic recombination of immunoglobulin gene segments GO:0016447 17 17 0,000 9,195E-03 0,01489186 ! cell-cell adherens junction GO:0005913 17 17 0,000 9,195E-03 0,01488511 ! triacylglycerol lipase activity GO:0004806 17 17 0,000 9,195E-03 0,01487837 ! ATP-dependent DNA helicase activity GO:0004003 17 17 0,000 9,195E-03 0,01487163 ! positive regulation of ossification GO:0045778 19 18 0,000 9,734E-03 0,01573556 ! pteridine and derivative metabolic process GO:0042558 19 18 0,000 9,734E-03 0,01572844 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 9,734E-03 0,01572133 GO:0005763|mitochondrial small ribosomal subunit, ! signal complex assembly GO:0007172 18 18 0,000 9,734E-03 0,01571422 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 19 18 0,000 9,734E-03 0,01570712 ! limbic system development GO:0021761 18 18 0,000 9,734E-03 0,01570003 ! cellular response to hydrogen peroxide GO:0070301 18 18 0,000 9,734E-03 0,01569294 GO:0042744|hydrogen peroxide catabolic process, ! MHC class II protein complex GO:0042613 18 18 0,000 9,734E-03 0,01568586 ! positive regulation of proteolysis GO:0045862 19 18 0,000 9,734E-03 0,01567878 ! deoxyribonucleotide metabolic process GO:0009262 19 18 0,000 9,734E-03 0,01567171 ! lysosome organization GO:0007040 18 18 0,000 9,734E-03 0,01566465 ! central nervous system neuron development GO:0021954 19 18 0,000 9,734E-03 0,01565759 ! fatty acid beta-oxidation GO:0006635 18 18 0,000 9,734E-03 0,01565055 ! regulation of viral reproduction GO:0050792 18 18 0,000 9,734E-03 0,0156435 ! peptide cross-linking GO:0018149 20 18 0,000 9,734E-03 0,01563646 ! ventricular cardiac muscle morphogenesis GO:0055010 19 18 0,000 9,734E-03 0,01562943 ! presynaptic membrane GO:0042734 19 18 0,000 9,734E-03 0,01562241 ! embryonic digit morphogenesis GO:0042733 20 18 0,000 9,734E-03 0,01561539 ! neural crest cell migration GO:0001755 18 18 0,000 9,734E-03 0,01560838 ! transcription factor TFIID complex GO:0005669 19 18 0,000 9,734E-03 0,01560137 ! positive regulation of adaptive immune response GO:0002821 22 18 0,000 9,734E-03 0,01559437 ! positive regulation of intracellular transport GO:0032388 19 18 0,000 9,734E-03 0,01558738 ! negative regulation of intracellular transport GO:0032387 18 18 0,000 9,734E-03 0,01558039 ! peptidyl-serine modification GO:0018209 18 18 0,000 9,734E-03 0,01557341 ! cell-cell recognition GO:0009988 19 18 0,000 9,734E-03 0,01556644 ! vitamin D receptor binding GO:0042809 19 18 0,000 9,734E-03 0,01555947 ! porphyrin biosynthetic process GO:0006779 18 18 0,000 9,734E-03 0,01555251 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 18 0,000 9,734E-03 0,01554555 ! actin filament-based movement GO:0030048 18 18 0,000 9,734E-03 0,01553861 ! Rab GTPase binding GO:0017137 18 18 0,000 9,734E-03 0,01553166 ! histone deacetylase activity GO:0004407 19 18 0,000 9,734E-03 0,01552473 GO:0033558|protein deacetylase activity, ! protein import into nucleus, docking GO:0000059 18 18 0,000 9,734E-03 0,01551779 ! negative regulation of cell cycle process GO:0010948 18 18 0,000 9,734E-03 0,01551087 ! glycerol metabolic process GO:0006071 19 18 0,000 9,734E-03 0,01550395 ! post-Golgi vesicle-mediated transport GO:0006892 18 18 0,000 9,734E-03 0,01549704 ! intra-Golgi vesicle-mediated transport GO:0006891 18 18 0,000 9,734E-03 0,01549013 ! aminoglycan catabolic process GO:0006026 18 18 0,000 9,734E-03 0,01548323 ! aminoglycan biosynthetic process GO:0006023 18 18 0,000 9,734E-03 0,01547634 ! small conjugating protein binding GO:0032182 18 18 0,000 9,734E-03 0,01546945 ! memory GO:0007613 19 18 0,000 9,734E-03 0,01546257 ! C21-steroid hormone metabolic process GO:0008207 18 18 0,000 9,734E-03 0,0154557 ! regulation of DNA recombination GO:0000018 22 18 0,000 9,734E-03 0,01544883 ! protein phosphatase type 2A complex GO:0000159 20 18 0,000 9,734E-03 0,01544196 ! inactivation of MAPK activity GO:0000188 19 18 0,000 9,734E-03 0,01543511 ! pigmentation during development GO:0048066 21 18 0,000 9,734E-03 0,01542826 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 18 0,000 9,734E-03 0,01542141 ! acetylcholine binding GO:0042166 19 18 0,000 9,734E-03 0,01541457 ! neurotransmitter:sodium symporter activity GO:0005328 18 18 0,000 9,734E-03 0,01540774 ! neurotransmitter metabolic process GO:0042133 23 18 0,000 9,734E-03 0,01540091 ! neuromuscular junction development GO:0007528 21 18 0,000 9,734E-03 0,01539409 ! nonmotile primary cilium GO:0031513 19 18 0,000 9,734E-03 0,01538728 ! coreceptor activity GO:0015026 18 18 0,000 9,734E-03 0,01538047 ! behavioral interaction between organisms GO:0051705 18 18 0,000 9,734E-03 0,01537367 ! carbonate dehydratase activity GO:0004089 19 18 0,000 9,734E-03 0,01536687 ! cytolysis GO:0019835 18 18 0,000 9,734E-03 0,01536008 ! phosphate binding GO:0042301 19 18 0,000 9,734E-03 0,0153533 ! transport vesicle membrane GO:0030658 21 18 0,000 9,734E-03 0,01534652 ! specific transcriptional repressor activity GO:0016566 18 18 0,000 9,734E-03 0,01533974 ! DNA modification GO:0006304 20 18 0,000 9,734E-03 0,01533298 ! bicarbonate transmembrane transporter activity GO:0015106 19 18 0,000 9,734E-03 0,01532622 ! detection of chemical stimulus GO:0009593 19 18 0,000 9,734E-03 0,01531946 ! ionotropic glutamate receptor activity GO:0004970 20 18 0,000 9,734E-03 0,01531271 ! aspartic-type endopeptidase activity GO:0004190 19 18 0,000 9,734E-03 0,01530597 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 18 18 0,000 9,734E-03 0,01529923 ! 3'-5' exonuclease activity GO:0008408 18 18 0,000 9,734E-03 0,0152925 ! RNA polymerase II transcription mediator activity GO:0016455 19 18 0,000 9,734E-03 0,01528578 ! water-soluble vitamin biosynthetic process GO:0042364 19 18 0,000 9,734E-03 0,01527906 ! connexon complex GO:0005922 18 18 0,000 9,734E-03 0,01527235 ! solute:hydrogen antiporter activity GO:0015299 18 18 0,000 9,734E-03 0,01526564 ! mRNA export from nucleus GO:0006406 21 19 0,000 0,01027226 0,01610283 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 20 19 0,000 0,01027226 0,01609577 ! regulation of interferon-gamma production GO:0032649 20 19 0,000 0,01027226 0,01608871 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 20 19 0,000 0,01027226 0,01608165 ! anion:anion antiporter activity GO:0015301 20 19 0,000 0,01027226 0,01607461 ! cAMP metabolic process GO:0046058 19 19 0,000 0,01027226 0,01606757 ! spindle microtubule GO:0005876 20 19 0,000 0,01027226 0,01606053 ! retinoid metabolic process GO:0001523 19 19 0,000 0,01027226 0,0160535 GO:0016101|diterpenoid metabolic process, ! caspase activator activity GO:0008656 19 19 0,000 0,01027226 0,01604648 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 21 19 0,000 0,01027226 0,01603946 ! vacuolar transport GO:0007034 19 19 0,000 0,01027226 0,01603245 ! threonine-type endopeptidase activity GO:0004298 19 19 0,000 0,01027226 0,01602545 GO:0070003|threonine-type peptidase activity, ! myofibril assembly GO:0030239 19 19 0,000 0,01027226 0,01601845 GO:0055002|striated muscle cell development, ! monocarboxylic acid transmembrane transporter activity GO:0008028 20 19 0,000 0,01027226 0,01601146 ! positive regulation of multicellular organism growth GO:0040018 19 19 0,000 0,01027226 0,01600447 ! cell projection membrane GO:0031253 20 19 0,000 0,01027226 0,01599749 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01027226 0,01599052 ! transcriptional repressor complex GO:0017053 19 19 0,000 0,01027226 0,01598355 ! vitamin A metabolic process GO:0006776 19 19 0,000 0,01027226 0,01597659 ! positive regulation of myeloid cell differentiation GO:0045639 20 19 0,000 0,01027226 0,01596964 ! negative regulation of myeloid cell differentiation GO:0045638 19 19 0,000 0,01027226 0,01596269 ! glutamine family amino acid catabolic process GO:0009065 21 19 0,000 0,01027226 0,01595574 ! leukotriene biosynthetic process GO:0019370 19 19 0,000 0,01027226 0,01594881 GO:0043450|alkene biosynthetic process, ! gas transport GO:0015669 20 19 0,000 0,01027226 0,01594187 ! retinoid binding GO:0005501 19 19 0,000 0,01027226 0,01593495 GO:0019840|isoprenoid binding, ! peptide hormone secretion GO:0030072 20 19 0,000 0,01027226 0,01592803 ! protein stabilization GO:0050821 20 19 0,000 0,01027226 0,01592112 ! cellular monovalent inorganic cation homeostasis GO:0030004 20 19 0,000 0,01027226 0,01591421 ! myeloid leukocyte differentiation GO:0002573 21 19 0,000 0,01027226 0,01590731 ! microtubule-based transport GO:0010970 19 19 0,000 0,01027226 0,01590041 ! protein complex scaffold GO:0032947 19 19 0,000 0,01027226 0,01589352 ! SNAP receptor activity GO:0005484 21 19 0,000 0,01027226 0,01588664 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01027226 0,01587976 GO:0006479|protein amino acid methylation, ! regulation of systemic arterial blood pressure by hormone GO:0001990 19 19 0,000 0,01027226 0,01587289 GO:0050886|endocrine process, ! visual behavior GO:0007632 22 19 0,000 0,01027226 0,01586603 GO:0008542|visual learning, ! 4 iron, 4 sulfur cluster binding GO:0051539 21 19 0,000 0,01027226 0,01585917 ! glycoprotein binding GO:0001948 23 19 0,000 0,01027226 0,01585231 ! sensory perception of taste GO:0050909 19 19 0,000 0,01027226 0,01584547 ! myoblast differentiation GO:0045445 19 19 0,000 0,01027226 0,01583862 ! cell differentiation in spinal cord GO:0021515 19 19 0,000 0,01027226 0,01583179 ! immune response-activating cell surface receptor signaling pathway GO:0002429 25 19 0,000 0,01027226 0,01582496 ! myosin binding GO:0017022 19 19 0,000 0,01027226 0,01581813 ! organic acid:sodium symporter activity GO:0005343 19 19 0,000 0,01027226 0,01581132 ! cell aging GO:0007569 19 19 0,000 0,01027226 0,0158045 ! stem cell differentiation GO:0048863 19 19 0,000 0,01027226 0,0157977 ! regulation of myeloid leukocyte differentiation GO:0002761 21 19 0,000 0,01027226 0,0157909 ! heart process GO:0003015 20 19 0,000 0,01027226 0,0157841 GO:0060047|heart contraction, ! mismatch repair GO:0006298 19 19 0,000 0,01027226 0,01577731 ! secretory granule membrane GO:0030667 20 19 0,000 0,01027226 0,01577053 ! MHC protein binding GO:0042287 19 19 0,000 0,01027226 0,01576375 ! extracellular-glutamate-gated ion channel activity GO:0005234 21 19 0,000 0,01027226 0,01575698 ! chloride transmembrane transporter activity GO:0015108 20 19 0,000 0,01027226 0,01575022 ! GABA-A receptor activity GO:0004890 20 19 0,000 0,01027226 0,01574346 ! response to cytokine stimulus GO:0034097 20 19 0,000 0,01027226 0,0157367 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01027226 0,01572995 ! translation elongation factor activity GO:0003746 22 19 0,000 0,01027226 0,01572321 ! insulin receptor binding GO:0005158 20 19 0,000 0,01027226 0,01571647 ! phosphoprotein phosphatase inhibitor activity GO:0004864 21 19 0,000 0,01027226 0,01570974 ! protein secretion GO:0009306 20 20 0,000 0,01081034 0,01652557 ! positive regulation of angiogenesis GO:0045766 22 20 0,000 0,01081034 0,0165185 ! proteasome core complex GO:0005839 20 20 0,000 0,01081034 0,01651143 ! positive regulation of bone remodeling GO:0046852 21 20 0,000 0,01081034 0,01650437 ! heterophilic cell adhesion GO:0007157 21 20 0,000 0,01081034 0,01649732 ! glutathione transferase activity GO:0004364 20 20 0,000 0,01081034 0,01649027 ! microtubule organizing center organization GO:0031023 20 20 0,000 0,01081034 0,01648323 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 20 20 0,000 0,01081034 0,0164762 ! actomyosin GO:0042641 20 20 0,000 0,01081034 0,01646917 ! positive regulation of innate immune response GO:0045089 20 20 0,000 0,01081034 0,01646215 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 20 0,000 0,01081034 0,01645513 ! vacuole organization GO:0007033 20 20 0,000 0,01081034 0,01644812 ! oxidoreductase activity, acting on heme group of donors GO:0016675 21 20 0,000 0,01081034 0,01644111 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! purine ribonucleoside metabolic process GO:0046128 23 20 0,000 0,01081034 0,01643411 GO:0042278|purine nucleoside metabolic process, ! chromosome condensation GO:0030261 20 20 0,000 0,01081034 0,01642712 ! regulation of exocytosis GO:0017157 21 20 0,000 0,01081034 0,01642013 ! vitamin biosynthetic process GO:0009110 21 20 0,000 0,01081034 0,01641315 ! glycosphingolipid metabolic process GO:0006687 20 20 0,000 0,01081034 0,01640618 ! kinase activator activity GO:0019209 20 20 0,000 0,01081034 0,01639921 ! diencephalon development GO:0021536 20 20 0,000 0,01081034 0,01639224 ! nuclear inner membrane GO:0005637 20 20 0,000 0,01081034 0,01638528 ! positive regulation of locomotion GO:0040017 20 20 0,000 0,01081034 0,01637833 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! synaptic vesicle transport GO:0048489 21 20 0,000 0,01081034 0,01637139 ! proteoglycan biosynthetic process GO:0030166 20 20 0,000 0,01081034 0,01636445 ! negative regulation of Wnt receptor signaling pathway GO:0030178 21 20 0,000 0,01081034 0,01635751 ! leukocyte homeostasis GO:0001776 22 20 0,000 0,01081034 0,01635058 ! regulation of blood coagulation GO:0030193 22 20 0,000 0,01081034 0,01634366 ! positive regulation of osteoblast differentiation GO:0045669 22 20 0,000 0,01081034 0,01633675 ! regulation of generation of precursor metabolites and energy GO:0043467 21 20 0,000 0,01081034 0,01632984 ! ligase activity, forming carbon-sulfur bonds GO:0016877 20 20 0,000 0,01081034 0,01632293 ! phosphorus-oxygen lyase activity GO:0016849 20 20 0,000 0,01081034 0,01631603 ! embryonic organ morphogenesis GO:0048562 22 20 0,000 0,01081034 0,01630914 ! alditol metabolic process GO:0019400 21 20 0,000 0,01081034 0,01630225 ! liver development GO:0001889 20 20 0,000 0,01081034 0,01629537 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 20 0,000 0,01081034 0,01628849 ! chromosome, telomeric region GO:0000781 21 20 0,000 0,01081034 0,01628162 ! calcium-independent cell-cell adhesion GO:0016338 20 20 0,000 0,01081034 0,01627476 ! response to alkaloid GO:0043279 22 20 0,000 0,01081034 0,0162679 ! transmembrane receptor protein phosphatase activity GO:0019198 27 20 0,000 0,01081034 0,01626105 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! smooth muscle contraction GO:0006939 21 20 0,000 0,01081034 0,0162542 ! heme metabolic process GO:0042168 22 20 0,000 0,01081034 0,01624736 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0,000 0,01081034 0,01624053 ! sex determination GO:0007530 20 20 0,000 0,01081034 0,0162337 ! negative regulation of protein catabolic process GO:0042177 21 20 0,000 0,01081034 0,01622687 ! peptide secretion GO:0002790 21 20 0,000 0,01081034 0,01622005 ! regulation of alpha-beta T cell activation GO:0046634 24 20 0,000 0,01081034 0,01621324 ! interaction with host GO:0051701 24 20 0,000 0,01081034 0,01620644 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 26 20 0,000 0,01081034 0,01619963 ! vasodilation GO:0042311 21 20 0,000 0,01081034 0,01619284 ! regulation of tumor necrosis factor production GO:0032680 20 20 0,000 0,01081034 0,01618605 ! regulation of chromosome organization GO:0033044 20 20 0,000 0,01081034 0,01617927 ! inward rectifier potassium channel activity GO:0005242 20 20 0,000 0,01081034 0,01617249 ! activation of JUN kinase activity GO:0007257 20 20 0,000 0,01081034 0,01616572 ! cyclic nucleotide binding GO:0030551 22 20 0,000 0,01081034 0,01615895 ! somatic diversification of immunoglobulins GO:0016445 20 20 0,000 0,01081034 0,01615219 ! microvillus GO:0005902 20 20 0,000 0,01081034 0,01614543 ! tumor necrosis factor receptor binding GO:0005164 20 20 0,000 0,01081034 0,01613868 ! ATP-dependent RNA helicase activity GO:0004004 20 20 0,000 0,01081034 0,01613194 ! positive regulation of protein catabolic process GO:0045732 22 21 0,000 0,01134816 0,01692744 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 22 21 0,000 0,01134816 0,01692037 ! growth cone GO:0030426 22 21 0,000 0,01134816 0,01691331 ! oligosaccharide metabolic process GO:0009311 23 21 0,000 0,01134816 0,01690626 ! regulation of anti-apoptosis GO:0045767 21 21 0,000 0,01134816 0,0168992 ! hormone secretion GO:0046879 22 21 0,000 0,01134816 0,01689216 ! protein amino acid O-linked glycosylation GO:0006493 22 21 0,000 0,01134816 0,01688512 ! transition metal ion transmembrane transporter activity GO:0046915 21 21 0,000 0,01134816 0,01687809 ! voltage-gated calcium channel complex GO:0005891 24 21 0,000 0,01134816 0,01687106 GO:0034704|calcium channel complex, ! dicarboxylic acid metabolic process GO:0043648 22 21 0,000 0,01134816 0,01686404 ! protein phosphatase type 2A regulator activity GO:0008601 23 21 0,000 0,01134816 0,01685703 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 24 21 0,000 0,01134816 0,01685002 ! histone-lysine N-methyltransferase activity GO:0018024 23 21 0,000 0,01134816 0,01684301 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! activation of pro-apoptotic gene products GO:0008633 22 21 0,000 0,01134816 0,01683602 ! mitochondrial membrane organization GO:0007006 22 21 0,000 0,01134816 0,01682903 ! central nervous system neuron differentiation GO:0021953 22 21 0,000 0,01134816 0,01682204 ! Golgi stack GO:0005795 25 21 0,000 0,01134816 0,01681506 ! regulation of endothelial cell migration GO:0010594 21 21 0,000 0,01134816 0,01680809 ! muscle cell development GO:0055001 21 21 0,000 0,01134816 0,01680112 ! cholesterol biosynthetic process GO:0006695 22 21 0,000 0,01134816 0,01679415 ! regulation of vasoconstriction GO:0019229 22 21 0,000 0,01134816 0,0167872 ! deacetylase activity GO:0019213 22 21 0,000 0,01134816 0,01678025 ! phosphatase inhibitor activity GO:0019212 23 21 0,000 0,01134816 0,0167733 ! regulation of fatty acid metabolic process GO:0019217 22 21 0,000 0,01134816 0,01676636 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,01134816 0,01675943 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! sensory perception of pain GO:0019233 21 21 0,000 0,01134816 0,0167525 ! pentose metabolic process GO:0019321 22 21 0,000 0,01134816 0,01674558 ! collagen fibril organization GO:0030199 22 21 0,000 0,01134816 0,01673866 ! platelet activation GO:0030168 23 21 0,000 0,01134816 0,01673175 ! response to glucocorticoid stimulus GO:0051384 22 21 0,000 0,01134816 0,01672484 ! trans-Golgi network transport vesicle GO:0030140 24 21 0,000 0,01134816 0,01671794 ! glutathione metabolic process GO:0006749 21 21 0,000 0,01134816 0,01671105 ! DNA-directed RNA polymerase complex GO:0000428 22 21 0,000 0,01134816 0,01670416 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! terpenoid metabolic process GO:0006721 21 21 0,000 0,01134816 0,01669728 ! cyclase activity GO:0009975 21 21 0,000 0,01134816 0,0166904 ! intramolecular transferase activity GO:0016866 22 21 0,000 0,01134816 0,01668353 ! negative regulation of cytokine production GO:0001818 21 21 0,000 0,01134816 0,01667666 ! fatty acid binding GO:0005504 21 21 0,000 0,01134816 0,0166698 ! gut development GO:0048565 21 21 0,000 0,01134816 0,01666295 ! acetyl-CoA catabolic process GO:0046356 21 21 0,000 0,01134816 0,0166561 GO:0006099|tricarboxylic acid cycle, ! phosphoinositide phospholipase C activity GO:0004435 21 21 0,000 0,01134816 0,01664926 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! protein tetramerization GO:0051262 22 21 0,000 0,01134816 0,01664242 ! regulation of microtubule polymerization or depolymerization GO:0031110 23 21 0,000 0,01134816 0,01663559 ! positive regulation of fibroblast proliferation GO:0048146 22 21 0,000 0,01134816 0,01662876 ! sulfur amino acid metabolic process GO:0000096 22 21 0,000 0,01134816 0,01662194 ! voltage-gated anion channel activity GO:0008308 21 21 0,000 0,01134816 0,01661513 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,01134816 0,01660832 ! cellular polysaccharide biosynthetic process GO:0033692 21 21 0,000 0,01134816 0,01660151 ! positive regulation of JAK-STAT cascade GO:0046427 22 21 0,000 0,01134816 0,01659471 ! sterol binding GO:0032934 21 21 0,000 0,01134816 0,01658792 ! regulation of chemotaxis GO:0050920 21 21 0,000 0,01134816 0,01658113 ! regulation of carbohydrate metabolic process GO:0006109 22 21 0,000 0,01134816 0,01657435 GO:0010675|regulation of cellular carbohydrate metabolic process, ! superoxide metabolic process GO:0006801 21 21 0,000 0,01134816 0,01656758 ! calcium-dependent cell-cell adhesion GO:0016339 21 21 0,000 0,01134816 0,01656081 ! phosphatase binding GO:0019902 22 21 0,000 0,01134816 0,01655404 ! NAD+ ADP-ribosyltransferase activity GO:0003950 21 21 0,000 0,01134816 0,01654728 ! positive regulation of cytoskeleton organization GO:0051495 21 21 0,000 0,01134816 0,01654053 ! negative regulation of DNA replication GO:0008156 25 21 0,000 0,01134816 0,01653378 ! vesicle targeting GO:0006903 22 21 0,000 0,01134816 0,01652704 ! vesicle docking during exocytosis GO:0006904 21 21 0,000 0,01134816 0,0165203 ! cell structure disassembly during apoptosis GO:0006921 21 21 0,000 0,01134816 0,01651357 ! RNA-dependent ATPase activity GO:0008186 21 21 0,000 0,01134816 0,01650684 ! renal system process GO:0003014 22 21 0,000 0,01134816 0,01650012 ! base-excision repair GO:0006284 21 21 0,000 0,01134816 0,0164934 ! positive regulation of leukocyte mediated immunity GO:0002705 25 21 0,000 0,01134816 0,01648669 GO:0002708|positive regulation of lymphocyte mediated immunity, ! nuclear-transcribed mRNA catabolic process GO:0000956 22 21 0,000 0,01134816 0,01647999 ! apoptotic protease activator activity GO:0016505 21 21 0,000 0,01134816 0,01647329 ! fatty acid transport GO:0015908 21 21 0,000 0,01134816 0,0164666 ! sarcoplasmic reticulum GO:0016529 22 21 0,000 0,01134816 0,01645991 ! positive regulation of tissue remodeling GO:0034105 22 21 0,000 0,01134816 0,01645323 ! collagen catabolic process GO:0030574 21 21 0,000 0,01134816 0,01644655 ! pyrimidine nucleotide biosynthetic process GO:0006221 25 21 0,000 0,01134816 0,01643988 ! regulation of multi-organism process GO:0043900 21 21 0,000 0,01134816 0,01643321 ! ubiquitin-specific protease activity GO:0004843 22 21 0,000 0,01134816 0,01642655 ! positive regulation of DNA replication GO:0045740 23 22 0,000 0,01188573 0,01719771 ! site of polarized growth GO:0030427 23 22 0,000 0,01188573 0,01719074 ! leukocyte adhesion GO:0007159 27 22 0,000 0,01188573 0,01718378 ! glutamate signaling pathway GO:0007215 25 22 0,000 0,01188573 0,01717683 ! potassium channel regulator activity GO:0015459 24 22 0,000 0,01188573 0,01716988 ! peroxisome organization GO:0007031 22 22 0,000 0,01188573 0,01716294 ! cellular response to reactive oxygen species GO:0034614 22 22 0,000 0,01188573 0,017156 ! polysaccharide catabolic process GO:0000272 22 22 0,000 0,01188573 0,01714907 ! response to starvation GO:0042594 23 22 0,000 0,01188573 0,01714214 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 22 22 0,000 0,01188573 0,01713522 ! coenzyme catabolic process GO:0009109 22 22 0,000 0,01188573 0,01712831 ! regulation of insulin secretion GO:0050796 23 22 0,000 0,01188573 0,0171214 ! membrane depolarization GO:0051899 24 22 0,000 0,01188573 0,01711449 ! somitogenesis GO:0001756 23 22 0,000 0,01188573 0,01710759 ! regulation of cytokine secretion GO:0050707 22 22 0,000 0,01188573 0,0171007 ! natural killer cell activation GO:0030101 22 22 0,000 0,01188573 0,01709382 ! positive regulation of B cell activation GO:0050871 26 22 0,000 0,01188573 0,01708693 ! aromatic amino acid family metabolic process GO:0009072 25 22 0,000 0,01188573 0,01708006 ! basal plasma membrane GO:0009925 22 22 0,000 0,01188573 0,01707319 GO:0045178|basal part of cell, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 22 22 0,000 0,01188573 0,01706632 ! camera-type eye morphogenesis GO:0048593 25 22 0,000 0,01188573 0,01705946 ! telomere organization GO:0032200 23 22 0,000 0,01188573 0,01705261 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 24 22 0,000 0,01188573 0,01704576 GO:0060606|tube closure, ! response to molecule of bacterial origin GO:0002237 22 22 0,000 0,01188573 0,01703892 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 22 0,000 0,01188573 0,01703208 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 22 22 0,000 0,01188573 0,01702525 GO:0016444|somatic cell DNA recombination, ! cortical actin cytoskeleton GO:0030864 22 22 0,000 0,01188573 0,01701842 ! initiation of viral infection GO:0019059 22 22 0,000 0,01188573 0,0170116 ! RNA polymerase complex GO:0030880 23 22 0,000 0,01188573 0,01700478 ! regulation of neurotransmitter transport GO:0051588 23 22 0,000 0,01188573 0,01699797 ! macromolecular complex disassembly GO:0032984 23 22 0,000 0,01188573 0,01699117 ! response to ethanol GO:0045471 25 22 0,000 0,01188573 0,01698437 ! syntaxin binding GO:0019905 23 22 0,000 0,01188573 0,01697758 ! regulation of nitric oxide biosynthetic process GO:0045428 22 22 0,000 0,01188573 0,01697079 ! digestive system process GO:0022600 24 22 0,000 0,01188573 0,01696401 ! neurotransmitter transporter activity GO:0005326 22 22 0,000 0,01188573 0,01695723 ! autophagy GO:0006914 24 22 0,000 0,01188573 0,01695046 ! carbohydrate kinase activity GO:0019200 22 22 0,000 0,01188573 0,01694369 ! neuropeptide hormone activity GO:0005184 23 22 0,000 0,01188573 0,01693693 ! negative regulation of phosphorylation GO:0042326 26 22 0,000 0,01188573 0,01693017 ! transaminase activity GO:0008483 23 22 0,000 0,01188573 0,01692342 ! sarcoplasm GO:0016528 23 22 0,000 0,01188573 0,01691668 ! metallocarboxypeptidase activity GO:0004181 23 22 0,000 0,01188573 0,01690994 ! cellular response to nutrient levels GO:0031669 23 22 0,000 0,01188573 0,0169032 ! positive regulation of nuclear division GO:0051785 22 22 0,000 0,01188573 0,01689647 GO:0045840|positive regulation of mitosis, ! nerve-nerve synaptic transmission GO:0007270 25 22 0,000 0,01188573 0,01688975 ! small conjugating protein-specific protease activity GO:0019783 24 22 0,000 0,01188573 0,01688303 ! pyrimidine nucleoside metabolic process GO:0006213 25 22 0,000 0,01188573 0,01687632 ! solute:cation antiporter activity GO:0015298 22 22 0,000 0,01188573 0,01686961 ! vesicle docking GO:0048278 23 23 0,000 0,01242304 0,01762522 ! muscle myosin complex GO:0005859 25 23 0,000 0,01242304 0,01761822 ! vasculogenesis GO:0001570 25 23 0,000 0,01242304 0,01761123 ! regulation of innate immune response GO:0045088 23 23 0,000 0,01242304 0,01760424 ! androgen receptor binding GO:0050681 23 23 0,000 0,01242304 0,01759725 ! positive regulation of epithelial cell proliferation GO:0050679 24 23 0,000 0,01242304 0,01759028 ! sperm motility GO:0030317 23 23 0,000 0,01242304 0,01758331 ! response to corticosteroid stimulus GO:0031960 24 23 0,000 0,01242304 0,01757634 ! apoptotic nuclear changes GO:0030262 23 23 0,000 0,01242304 0,01756938 ! barbed-end actin filament capping GO:0051016 23 23 0,000 0,01242304 0,01756242 GO:0051693|actin filament capping, ! negative regulation of phosphorus metabolic process GO:0010563 27 23 0,000 0,01242304 0,01755547 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 24 23 0,000 0,01242304 0,01754853 ! regulation of behavior GO:0050795 23 23 0,000 0,01242304 0,01754159 ! cardiac muscle tissue morphogenesis GO:0055008 24 23 0,000 0,01242304 0,01753466 GO:0060415|muscle tissue morphogenesis, ! cyclic nucleotide biosynthetic process GO:0009190 23 23 0,000 0,01242304 0,01752773 ! leukotriene metabolic process GO:0006691 23 23 0,000 0,01242304 0,01752081 ! positive regulation of T cell differentiation GO:0045582 27 23 0,000 0,01242304 0,01751389 ! glycolipid metabolic process GO:0006664 23 23 0,000 0,01242304 0,01750698 ! regulation of ARF GTPase activity GO:0032312 26 23 0,000 0,01242304 0,01750007 ! pallium development GO:0021543 23 23 0,000 0,01242304 0,01749317 ! GABA receptor activity GO:0016917 24 23 0,000 0,01242304 0,01748627 ! positive regulation of MAPKKK cascade GO:0043410 30 23 0,000 0,01242304 0,01747939 ! regulation of response to biotic stimulus GO:0002831 23 23 0,000 0,01242304 0,0174725 ! MHC class II receptor activity GO:0032395 23 23 0,000 0,01242304 0,01746562 ! nicotinamide metabolic process GO:0006769 23 23 0,000 0,01242304 0,01745875 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of neuron differentiation GO:0045665 23 23 0,000 0,01242304 0,01745188 ! aspartate family amino acid metabolic process GO:0009066 24 23 0,000 0,01242304 0,01744502 ! cell surface binding GO:0043498 25 23 0,000 0,01242304 0,01743816 ! collagen binding GO:0005518 27 23 0,000 0,01242304 0,01743131 ! insulin-like growth factor binding GO:0005520 23 23 0,000 0,01242304 0,01742446 ! regulation of amine transport GO:0051952 23 23 0,000 0,01242304 0,01741762 ! tissue homeostasis GO:0001894 24 23 0,000 0,01242304 0,01741078 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 25 23 0,000 0,01242304 0,01740395 ! protein import into nucleus, translocation GO:0000060 25 23 0,000 0,01242304 0,01739713 ! gluconeogenesis GO:0006094 24 23 0,000 0,01242304 0,01739031 ! iron ion transport GO:0006826 24 23 0,000 0,01242304 0,0173835 ! nucleotide-excision repair, DNA damage removal GO:0000718 24 23 0,000 0,01242304 0,01737669 ! N-acetylglucosamine metabolic process GO:0006044 23 23 0,000 0,01242304 0,01736988 ! molting cycle process GO:0022404 23 23 0,000 0,01242304 0,01736308 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! circadian rhythm GO:0007623 24 23 0,000 0,01242304 0,01735629 ! tube lumen formation GO:0035148 26 23 0,000 0,01242304 0,0173495 ! insulin receptor signaling pathway GO:0008286 28 23 0,000 0,01242304 0,01734272 ! multicellular organismal response to stress GO:0033555 23 23 0,000 0,01242304 0,01733594 ! immune response-activating signal transduction GO:0002757 29 23 0,000 0,01242304 0,01732917 ! lymphocyte proliferation GO:0046651 29 23 0,000 0,01242304 0,01732241 ! fibroblast growth factor receptor signaling pathway GO:0008543 24 23 0,000 0,01242304 0,01731564 ! regulation of bone mineralization GO:0030500 25 23 0,000 0,01242304 0,01730889 ! single-stranded RNA binding GO:0003727 24 23 0,000 0,01242304 0,01730214 ! brush border GO:0005903 25 23 0,000 0,01242304 0,01729539 ! caveola GO:0005901 24 23 0,000 0,01242304 0,01728865 ! gap junction GO:0005921 23 23 0,000 0,01242304 0,01728192 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 25 24 0,000 0,0129601 0,018022 ! regulation of transmembrane transport GO:0034762 24 24 0,000 0,0129601 0,01801499 ! heterotrimeric G-protein complex GO:0005834 24 24 0,000 0,0129601 0,01800798 ! protein amino acid acylation GO:0043543 26 24 0,000 0,0129601 0,01800097 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 24 0,000 0,0129601 0,01799397 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 25 24 0,000 0,0129601 0,01798698 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,0129601 0,01797999 ! MHC class I protein complex GO:0042612 24 24 0,000 0,0129601 0,01797301 ! G-protein chemoattractant receptor activity GO:0001637 24 24 0,000 0,0129601 0,01796603 GO:0004950|chemokine receptor activity, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 24 24 0,000 0,0129601 0,01795906 ! early endosome membrane GO:0031901 26 24 0,000 0,0129601 0,0179521 ! primary neural tube formation GO:0014020 26 24 0,000 0,0129601 0,01794513 ! ARF GTPase activator activity GO:0008060 27 24 0,000 0,0129601 0,01793818 ! hydrogen peroxide metabolic process GO:0042743 24 24 0,000 0,0129601 0,01793123 ! immunoglobulin production GO:0002377 28 24 0,000 0,0129601 0,01792428 GO:0002440|production of molecular mediator of immune response, ! lipid kinase activity GO:0001727 26 24 0,000 0,0129601 0,01791735 ! positive regulation of protein secretion GO:0050714 26 24 0,000 0,0129601 0,01791041 ! MHC class I receptor activity GO:0032393 24 24 0,000 0,0129601 0,01790348 ! RNA splicing factor activity, transesterification mechanism GO:0031202 24 24 0,000 0,0129601 0,01789656 ! fat-soluble vitamin metabolic process GO:0006775 24 24 0,000 0,0129601 0,01788964 ! regulation of osteoblast differentiation GO:0045667 27 24 0,000 0,0129601 0,01788273 ! cellular alkene metabolic process GO:0043449 24 24 0,000 0,0129601 0,01787582 ! somatic diversification of immune receptors GO:0002200 24 24 0,000 0,0129601 0,01786892 ! calcium-dependent phospholipid binding GO:0005544 24 24 0,000 0,0129601 0,01786202 ! positive regulation of JUN kinase activity GO:0043507 24 24 0,000 0,0129601 0,01785513 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 26 24 0,000 0,0129601 0,01784825 ! Z disc GO:0030018 27 24 0,000 0,0129601 0,01784137 ! negative regulation of lymphocyte activation GO:0051250 24 24 0,000 0,0129601 0,01783449 ! regulation of fibroblast proliferation GO:0048145 25 24 0,000 0,0129601 0,01782762 ! alkaloid metabolic process GO:0009820 24 24 0,000 0,0129601 0,01782076 ! neuron fate commitment GO:0048663 24 24 0,000 0,0129601 0,0178139 ! DNA catabolic process, endonucleolytic GO:0000737 24 24 0,000 0,0129601 0,01780704 ! glucosamine metabolic process GO:0006041 24 24 0,000 0,0129601 0,01780019 ! regulation of transcription factor import into nucleus GO:0042990 25 24 0,000 0,0129601 0,01779335 ! glucose transport GO:0015758 24 24 0,000 0,0129601 0,01778651 ! dendrite development GO:0016358 26 24 0,000 0,0129601 0,01777968 ! catechol metabolic process GO:0009712 27 24 0,000 0,0129601 0,01777285 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phospholipase A2 activity GO:0004623 26 24 0,000 0,0129601 0,01776603 ! immune response-regulating signal transduction GO:0002764 30 24 0,000 0,0129601 0,01775921 ! regulation of production of molecular mediator of immune response GO:0002700 28 24 0,000 0,0129601 0,0177524 ! DNA-directed DNA polymerase activity GO:0003887 25 24 0,000 0,0129601 0,01774559 ! synaptogenesis GO:0007416 25 24 0,000 0,0129601 0,01773879 ! selenium binding GO:0008430 24 24 0,000 0,0129601 0,01773199 ! leukocyte proliferation GO:0070661 30 24 0,000 0,0129601 0,0177252 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 26 24 0,000 0,0129601 0,01771842 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 25 25 0,000 0,0134969 0,01844524 ! phenol metabolic process GO:0018958 28 25 0,000 0,0134969 0,01843818 ! epidermal growth factor receptor signaling pathway GO:0007173 28 25 0,000 0,0134969 0,01843113 ! hexose transport GO:0008645 25 25 0,000 0,0134969 0,01842409 GO:0015749|monosaccharide transport, ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 27 25 0,000 0,0134969 0,01841705 ! PML body GO:0016605 28 25 0,000 0,0134969 0,01841001 ! regulation of cellular ketone metabolic process GO:0010565 26 25 0,000 0,0134969 0,01840298 ! negative regulation of cell development GO:0010721 28 25 0,000 0,0134969 0,01839596 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 27 25 0,000 0,0134969 0,01838894 ! cell fate determination GO:0001709 25 25 0,000 0,0134969 0,01838193 ! regulation of oxidoreductase activity GO:0051341 25 25 0,000 0,0134969 0,01837492 ! group transfer coenzyme metabolic process GO:0006752 26 25 0,000 0,0134969 0,01836792 ! hormone transport GO:0009914 26 25 0,000 0,0134969 0,01836092 ! neuromuscular process controlling balance GO:0050885 26 25 0,000 0,0134969 0,01835393 ! porphyrin metabolic process GO:0006778 27 25 0,000 0,0134969 0,01834694 GO:0033013|tetrapyrrole metabolic process, ! blastocyst development GO:0001824 25 25 0,000 0,0134969 0,01833996 ! regulation of JUN kinase activity GO:0043506 25 25 0,000 0,0134969 0,01833298 ! cell adhesion molecule binding GO:0050839 27 25 0,000 0,0134969 0,01832601 ! negative regulation of actin filament depolymerization GO:0030835 25 25 0,000 0,0134969 0,01831905 ! acetyl-CoA metabolic process GO:0006084 25 25 0,000 0,0134969 0,01831209 ! membrane lipid catabolic process GO:0046466 26 25 0,000 0,0134969 0,01830513 ! zinc ion transport GO:0006829 26 25 0,000 0,0134969 0,01829818 ! heterochromatin GO:0000792 26 25 0,000 0,0134969 0,01829124 ! cellular iron ion homeostasis GO:0006879 25 25 0,000 0,0134969 0,0182843 ! phototransduction GO:0007602 25 25 0,000 0,0134969 0,01827737 ! keratinization GO:0031424 26 25 0,000 0,0134969 0,01827044 ! spinal cord development GO:0021510 25 25 0,000 0,0134969 0,01826351 ! cyclin-dependent protein kinase activity GO:0004693 26 25 0,000 0,0134969 0,0182566 ! regulation of smooth muscle contraction GO:0006940 28 25 0,000 0,0134969 0,01824968 ! response to toxin GO:0009636 25 25 0,000 0,0134969 0,01824278 ! regulation of peptide secretion GO:0002791 26 25 0,000 0,0134969 0,01823587 ! determination of left/right symmetry GO:0007368 25 25 0,000 0,0134969 0,01822898 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 25 0,000 0,0134969 0,01822208 ! regulation of interleukin-6 production GO:0032675 25 25 0,000 0,0134969 0,0182152 ! voltage-gated calcium channel activity GO:0005245 28 25 0,000 0,0134969 0,01820832 ! phospholipid transport GO:0015914 26 25 0,000 0,0134969 0,01820144 ! peptidase activator activity GO:0016504 25 25 0,000 0,0134969 0,01819457 ! protein localization in mitochondrion GO:0070585 26 25 0,000 0,0134969 0,0181877 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 25 25 0,000 0,0134969 0,01818084 ! regulation of microtubule cytoskeleton organization GO:0070507 27 25 0,000 0,0134969 0,01817399 ! ethanolamine and derivative metabolic process GO:0042439 28 25 0,000 0,0134969 0,01816714 ! small nuclear ribonucleoprotein complex GO:0030532 25 25 0,000 0,0134969 0,01816029 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 25 25 0,000 0,0134969 0,01815345 ! negative regulation of transcription regulator activity GO:0090048 26 25 0,000 0,0134969 0,01814662 GO:0043433|negative regulation of transcription factor activity, ! acetylgalactosaminyltransferase activity GO:0008376 27 25 0,000 0,0134969 0,01813979 ! solute:solute antiporter activity GO:0015300 26 26 0,000 0,01403344 0,0188538 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 27 26 0,000 0,01403344 0,01884671 ! regeneration GO:0031099 26 26 0,000 0,01403344 0,01883963 ! cholesterol homeostasis GO:0042632 26 26 0,000 0,01403344 0,01883255 GO:0055092|sterol homeostasis, ! peptidyl-tyrosine phosphorylation GO:0018108 27 26 0,000 0,01403344 0,01882547 ! ureteric bud development GO:0001657 26 26 0,000 0,01403344 0,0188184 ! neural crest cell development GO:0014032 26 26 0,000 0,01403344 0,01881134 GO:0014033|neural crest cell differentiation, ! negative regulation of protein kinase cascade GO:0010741 27 26 0,000 0,01403344 0,01880428 ! cellular response to oxidative stress GO:0034599 26 26 0,000 0,01403344 0,01879723 ! lipid oxidation GO:0034440 26 26 0,000 0,01403344 0,01879018 GO:0019395|fatty acid oxidation, ! positive regulation of lymphocyte differentiation GO:0045621 30 26 0,000 0,01403344 0,01878314 ! pyridine nucleotide metabolic process GO:0019362 26 26 0,000 0,01403344 0,0187761 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 26 26 0,000 0,01403344 0,01876907 ! carboxy-lyase activity GO:0016831 26 26 0,000 0,01403344 0,01876204 ! myeloid leukocyte activation GO:0002274 27 26 0,000 0,01403344 0,01875502 ! negative regulation of neuron apoptosis GO:0043524 26 26 0,000 0,01403344 0,018748 ! negative regulation of catabolic process GO:0009895 28 26 0,000 0,01403344 0,01874099 ! lysine N-acetyltransferase activity GO:0004468 26 26 0,000 0,01403344 0,01873399 GO:0004402|histone acetyltransferase activity, ! regulation of actin filament depolymerization GO:0030834 26 26 0,000 0,01403344 0,01872698 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,01403344 0,01871999 ! determination of bilateral symmetry GO:0009855 26 26 0,000 0,01403344 0,018713 GO:0009799|determination of symmetry, ! regulation of cellular catabolic process GO:0031329 28 26 0,000 0,01403344 0,01870601 ! pyruvate metabolic process GO:0006090 27 26 0,000 0,01403344 0,01869903 ! cellular component assembly involved in morphogenesis GO:0010927 26 26 0,000 0,01403344 0,01869206 ! histone methyltransferase activity GO:0042054 29 26 0,000 0,01403344 0,01868509 ! regulation of endothelial cell proliferation GO:0001936 27 26 0,000 0,01403344 0,01867813 ! chemokine binding GO:0019956 26 26 0,000 0,01403344 0,01867117 ! receptor metabolic process GO:0043112 28 26 0,000 0,01403344 0,01866421 ! nucleotide kinase activity GO:0019201 30 26 0,000 0,01403344 0,01865726 ! histone deacetylase complex GO:0000118 27 26 0,000 0,01403344 0,01865032 ! phospholipase C activity GO:0004629 27 26 0,000 0,01403344 0,01864338 ! cellular response to extracellular stimulus GO:0031668 27 26 0,000 0,01403344 0,01863645 ! negative regulation of leukocyte activation GO:0002695 26 26 0,000 0,01403344 0,01862952 ! receptor regulator activity GO:0030545 26 26 0,000 0,01403344 0,0186226 ! galactosyltransferase activity GO:0008378 27 26 0,000 0,01403344 0,01861568 ! positive regulation of immune effector process GO:0002699 30 26 0,000 0,01403344 0,01860877 ! mRNA catabolic process GO:0006402 28 27 0,000 0,01456973 0,01931273 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 28 27 0,000 0,01456973 0,01930557 ! actomyosin structure organization GO:0031032 28 27 0,000 0,01456973 0,0192984 ! nucleotide receptor activity, G-protein coupled GO:0001608 27 27 0,000 0,01456973 0,01929125 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 28 27 0,000 0,01456973 0,0192841 ! iron ion homeostasis GO:0055072 27 27 0,000 0,01456973 0,01927695 ! lipoprotein binding GO:0008034 29 27 0,000 0,01456973 0,01926981 ! deaminase activity GO:0019239 27 27 0,000 0,01456973 0,01926268 ! mesoderm formation GO:0001707 28 27 0,000 0,01456973 0,01925555 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 27 27 0,000 0,01456973 0,01924843 ! phospholipid transporter activity GO:0005548 29 27 0,000 0,01456973 0,01924131 ! neural tube formation GO:0001841 29 27 0,000 0,01456973 0,0192342 ! mitotic sister chromatid segregation GO:0000070 27 27 0,000 0,01456973 0,01922709 ! regulation of smooth muscle cell proliferation GO:0048660 27 27 0,000 0,01456973 0,01921998 ! integrin complex GO:0008305 28 27 0,000 0,01456973 0,01921289 ! nuclear chromatin GO:0000790 28 27 0,000 0,01456973 0,01920579 ! collagen metabolic process GO:0032963 27 27 0,000 0,01456973 0,01919871 ! post-embryonic development GO:0009791 29 27 0,000 0,01456973 0,01919163 ! antigen processing and presentation of peptide antigen GO:0048002 28 27 0,000 0,01456973 0,01918455 ! SNARE binding GO:0000149 28 27 0,000 0,01456973 0,01917748 ! biogenic amine biosynthetic process GO:0042401 28 27 0,000 0,01456973 0,01917041 ! spindle pole GO:0000922 28 27 0,000 0,01456973 0,01916335 ! anion:cation symporter activity GO:0015296 28 27 0,000 0,01456973 0,0191563 ! trans-Golgi network GO:0005802 29 28 0,000 0,01510576 0,01985376 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 28 0,000 0,01510576 0,01984646 ! cholesterol transport GO:0030301 28 28 0,000 0,01510576 0,01983916 GO:0015918|sterol transport, ! thyroid hormone receptor binding GO:0046966 29 28 0,000 0,01510576 0,01983187 ! dynein complex GO:0030286 29 28 0,000 0,01510576 0,01982458 ! formation of primary germ layer GO:0001704 29 28 0,000 0,01510576 0,01981729 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 30 28 0,000 0,01510576 0,01981002 ! peptidyl-tyrosine modification GO:0018212 29 28 0,000 0,01510576 0,01980274 ! deoxyribonuclease activity GO:0004536 28 28 0,000 0,01510576 0,01979548 ! cofactor catabolic process GO:0051187 30 28 0,000 0,01510576 0,01978821 ! DNA damage checkpoint GO:0000077 31 28 0,000 0,01510576 0,01978096 ! negative regulation of actin filament polymerization GO:0030837 28 28 0,000 0,01510576 0,01977371 ! cortical cytoskeleton GO:0030863 29 28 0,000 0,01510576 0,01976646 ! icosanoid biosynthetic process GO:0046456 29 28 0,000 0,01510576 0,01975922 ! amino sugar metabolic process GO:0006040 28 28 0,000 0,01510576 0,01975199 ! membrane docking GO:0022406 28 28 0,000 0,01510576 0,01974476 ! sister chromatid segregation GO:0000819 28 28 0,000 0,01510576 0,01973753 ! detection of light stimulus involved in sensory perception GO:0050962 28 28 0,000 0,01510576 0,01973031 GO:0050908|detection of light stimulus involved in visual perception, ! cell junction assembly GO:0034329 30 28 0,000 0,01510576 0,0197231 ! complement activation, classical pathway GO:0006958 31 28 0,000 0,01510576 0,01971589 ! multicellular organismal catabolic process GO:0044243 28 28 0,000 0,01510576 0,01970869 ! response to mechanical stimulus GO:0009612 28 28 0,000 0,01510576 0,01970149 ! caspase regulator activity GO:0043028 28 28 0,000 0,01510576 0,01969429 ! DNA polymerase activity GO:0034061 29 28 0,000 0,01510576 0,01968711 ! calcium-mediated signaling GO:0019722 28 28 0,000 0,01510576 0,01967992 ! neurotransmitter secretion GO:0007269 29 28 0,000 0,01510576 0,01967275 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 28 28 0,000 0,01510576 0,01966558 ! glycogen metabolic process GO:0005977 29 28 0,000 0,01510576 0,01965841 ! RNA helicase activity GO:0003724 28 28 0,000 0,01510576 0,01965125 ! Rho GTPase activator activity GO:0005100 32 28 0,000 0,01510576 0,01964409 ! symbiosis, encompassing mutualism through parasitism GO:0044403 32 28 0,000 0,01510576 0,01963694 ! transferase activity, transferring nitrogenous groups GO:0016769 30 29 0,000 0,01564154 0,02032603 ! spliceosomal snRNP biogenesis GO:0000387 30 29 0,000 0,01564154 0,02031864 ! odontogenesis of dentine-containing tooth GO:0042475 30 29 0,000 0,01564154 0,02031125 ! scavenger receptor activity GO:0005044 30 29 0,000 0,01564154 0,02030387 ! spindle organization GO:0007051 30 29 0,000 0,01564154 0,02029649 ! mesoderm morphogenesis GO:0048332 30 29 0,000 0,01564154 0,02028912 ! male gonad development GO:0008584 29 29 0,000 0,01564154 0,02028175 ! response to organic cyclic substance GO:0014070 31 29 0,000 0,01564154 0,02027439 ! negative regulation of MAP kinase activity GO:0043407 30 29 0,000 0,01564154 0,02026703 ! sterol biosynthetic process GO:0016126 30 29 0,000 0,01564154 0,02025968 ! endocytic vesicle GO:0030139 29 29 0,000 0,01564154 0,02025233 ! Rho GTPase binding GO:0017048 32 29 0,000 0,01564154 0,02024499 ! serine family amino acid metabolic process GO:0009069 30 29 0,000 0,01564154 0,02023766 ! fatty acid catabolic process GO:0009062 30 29 0,000 0,01564154 0,02023033 ! regulation of calcium ion transport GO:0051924 32 29 0,000 0,01564154 0,020223 ! negative regulation of protein polymerization GO:0032272 29 29 0,000 0,01564154 0,02021568 ! glucan metabolic process GO:0044042 30 29 0,000 0,01564154 0,02020837 GO:0006073|cellular glucan metabolic process, ! regulation of synaptic plasticity GO:0048167 29 29 0,000 0,01564154 0,02020106 ! proteoglycan metabolic process GO:0006029 30 29 0,000 0,01564154 0,02019376 ! xenobiotic metabolic process GO:0006805 29 29 0,000 0,01564154 0,02018646 ! negative regulation of response to external stimulus GO:0032102 29 29 0,000 0,01564154 0,02017917 ! positive regulation of T cell proliferation GO:0042102 33 29 0,000 0,01564154 0,02017188 ! steroid dehydrogenase activity GO:0016229 29 29 0,000 0,01564154 0,0201646 ! regulation of protein import into nucleus GO:0042306 30 29 0,000 0,01564154 0,02015732 ! clathrin coated vesicle membrane GO:0030665 32 29 0,000 0,01564154 0,02015005 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 30 29 0,000 0,01564154 0,02014278 ! cytosolic small ribosomal subunit GO:0022627 29 29 0,000 0,01564154 0,02013552 ! detection of visible light GO:0009584 29 29 0,000 0,01564154 0,02012827 ! tumor necrosis factor receptor superfamily binding GO:0032813 29 29 0,000 0,01564154 0,02012101 ! acetylglucosaminyltransferase activity GO:0008375 30 29 0,000 0,01564154 0,02011377 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,01564154 0,02010653 ! gene silencing GO:0016458 29 29 0,000 0,01564154 0,02009929 ! hormone binding GO:0042562 30 30 0,000 0,01617706 0,02077996 ! negative regulation of DNA metabolic process GO:0051053 34 30 0,000 0,01617706 0,02077249 ! inner ear morphogenesis GO:0042472 31 30 0,000 0,01617706 0,02076502 ! GPI anchor biosynthetic process GO:0006506 32 30 0,000 0,01617706 0,02075756 ! acrosomal vesicle GO:0001669 32 30 0,000 0,01617706 0,0207501 ! negative regulation of DNA binding GO:0043392 31 30 0,000 0,01617706 0,02074265 ! triglyceride metabolic process GO:0006641 31 30 0,000 0,01617706 0,02073521 ! erythrocyte differentiation GO:0030218 32 30 0,000 0,01617706 0,02072777 ! glutamate receptor activity GO:0008066 33 30 0,000 0,01617706 0,02072033 ! ceramide metabolic process GO:0006672 30 30 0,000 0,01617706 0,0207129 ! cell fate specification GO:0001708 31 30 0,000 0,01617706 0,02070548 ! hexose biosynthetic process GO:0019319 32 30 0,000 0,01617706 0,02069806 ! PDZ domain binding GO:0030165 32 30 0,000 0,01617706 0,02069065 ! AP-type membrane coat adaptor complex GO:0030119 31 30 0,000 0,01617706 0,02068324 GO:0030131|clathrin adaptor complex, ! embryonic epithelial tube formation GO:0001838 32 30 0,000 0,01617706 0,02067584 ! negative regulation of cell activation GO:0050866 31 30 0,000 0,01617706 0,02066844 ! negative regulation of protein transport GO:0051224 30 30 0,000 0,01617706 0,02066105 ! negative regulation of protein complex assembly GO:0031333 30 30 0,000 0,01617706 0,02065366 ! regulation of JAK-STAT cascade GO:0046425 32 30 0,000 0,01617706 0,02064628 ! drug binding GO:0008144 30 30 0,000 0,01617706 0,0206389 ! multicellular organismal macromolecule metabolic process GO:0044259 30 30 0,000 0,01617706 0,02063153 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 33 30 0,000 0,01617706 0,02062417 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,01617706 0,02061681 ! regulation of systemic arterial blood pressure GO:0003073 32 30 0,000 0,01617706 0,02060945 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 31 30 0,000 0,01617706 0,0206021 ! aminopeptidase activity GO:0004177 32 30 0,000 0,01617706 0,02059476 ! detection of light stimulus GO:0009583 30 30 0,000 0,01617706 0,02058742 ! L-amino acid transmembrane transporter activity GO:0015179 30 30 0,000 0,01617706 0,02058008 ! regulation of microtubule-based process GO:0032886 32 30 0,000 0,01617706 0,02057275 ! cysteine-type endopeptidase inhibitor activity GO:0004869 32 30 0,000 0,01617706 0,02056543 ! meiosis I GO:0007127 31 31 0,000 0,01671233 0,02123834 ! negative regulation of cell adhesion GO:0007162 33 31 0,000 0,01671233 0,02123078 ! striated muscle cell differentiation GO:0051146 31 31 0,000 0,01671233 0,02122323 ! GPI anchor metabolic process GO:0006505 33 31 0,000 0,01671233 0,02121569 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,01671233 0,02120815 ! spliceosome assembly GO:0000245 32 31 0,000 0,01671233 0,02120062 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 32 31 0,000 0,01671233 0,02119309 GO:0004601|peroxidase activity, ! unsaturated fatty acid biosynthetic process GO:0006636 32 31 0,000 0,01671233 0,02118556 ! NAD or NADH binding GO:0051287 31 31 0,000 0,01671233 0,02117805 ! positive regulation of neurogenesis GO:0050769 32 31 0,000 0,01671233 0,02117053 ! cyclic nucleotide metabolic process GO:0009187 31 31 0,000 0,01671233 0,02116303 ! nucleotide catabolic process GO:0009166 32 31 0,000 0,01671233 0,02115552 ! replication fork GO:0005657 32 31 0,000 0,01671233 0,02114803 ! placenta development GO:0001890 31 31 0,000 0,01671233 0,02114054 ! condensed nuclear chromosome GO:0000794 32 31 0,000 0,01671233 0,02113305 ! regulation of pH GO:0006885 31 31 0,000 0,01671233 0,02112557 ! protein methyltransferase activity GO:0008276 36 31 0,000 0,01671233 0,02111809 ! acute-phase response GO:0006953 32 31 0,000 0,01671233 0,02111062 ! peptide transport GO:0015833 32 31 0,000 0,01671233 0,02110316 ! respiratory gaseous exchange GO:0007585 32 31 0,000 0,01671233 0,0210957 ! DNA integrity checkpoint GO:0031570 34 31 0,000 0,01671233 0,02108824 ! Golgi-associated vesicle membrane GO:0030660 34 31 0,000 0,01671233 0,0210808 ! regulation of protein stability GO:0031647 32 31 0,000 0,01671233 0,02107335 ! sarcolemma GO:0042383 33 31 0,000 0,01671233 0,02106591 ! vesicle localization GO:0051648 32 31 0,000 0,01671233 0,02105848 ! microtubule organizing center part GO:0044450 34 31 0,000 0,01671233 0,02105105 ! response to hydrogen peroxide GO:0042542 34 32 0,000 0,01724734 0,0217173 ! DNA helicase activity GO:0003678 34 32 0,000 0,01724734 0,02170965 ! NADP or NADPH binding GO:0050661 33 32 0,000 0,01724734 0,021702 ! pigment biosynthetic process GO:0046148 34 32 0,000 0,01724734 0,02169435 ! purinergic nucleotide receptor activity GO:0001614 34 32 0,000 0,01724734 0,02168671 GO:0016502|nucleotide receptor activity, ! late endosome membrane GO:0031902 32 32 0,000 0,01724734 0,02167908 ! positive regulation of cell development GO:0010720 33 32 0,000 0,01724734 0,02167145 ! regulation of Wnt receptor signaling pathway GO:0030111 35 32 0,000 0,01724734 0,02166383 ! hindbrain development GO:0030902 35 32 0,000 0,01724734 0,02165621 ! aerobic respiration GO:0009060 32 32 0,000 0,01724734 0,0216486 ! positive regulation of catabolic process GO:0009896 34 32 0,000 0,01724734 0,02164099 ! regulation of B cell activation GO:0050864 36 32 0,000 0,01724734 0,02163339 ! regulation of muscle development GO:0048634 33 32 0,000 0,01724734 0,0216258 GO:0016202|regulation of striated muscle tissue development, ! cation:sugar symporter activity GO:0005402 32 32 0,000 0,01724734 0,0216182 GO:0005351|sugar:hydrogen symporter activity, ! sphingoid metabolic process GO:0046519 32 32 0,000 0,01724734 0,02161062 ! response to ionizing radiation GO:0010212 33 32 0,000 0,01724734 0,02160304 ! flagellum GO:0019861 32 32 0,000 0,01724734 0,02159546 ! regulation of lymphocyte mediated immunity GO:0002706 36 32 0,000 0,01724734 0,0215879 ! I band GO:0031674 35 32 0,000 0,01724734 0,02158033 ! JAK-STAT cascade GO:0007259 34 32 0,000 0,01724734 0,02157277 ! double-stranded RNA binding GO:0003725 33 32 0,000 0,01724734 0,02156522 ! cellular response to insulin stimulus GO:0032869 37 32 0,000 0,01724734 0,02155767 ! adult locomotory behavior GO:0008344 33 32 0,000 0,01724734 0,02155013 ! pyrimidine nucleotide metabolic process GO:0006220 37 32 0,000 0,01724734 0,02154259 ! positive regulation of transcription factor activity GO:0051091 34 33 0,000 0,0177821 0,02220276 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 34 33 0,000 0,0177821 0,022195 ! establishment or maintenance of cell polarity GO:0007163 33 33 0,000 0,0177821 0,02218724 ! platelet alpha granule lumen GO:0031093 34 33 0,000 0,0177821 0,02217949 ! negative regulation of binding GO:0051100 34 33 0,000 0,0177821 0,02217175 ! organelle envelope lumen GO:0031970 34 33 0,000 0,0177821 0,02216401 ! protein targeting to membrane GO:0006612 35 33 0,000 0,0177821 0,02215628 ! vesicle coat GO:0030120 36 33 0,000 0,0177821 0,02214855 ! endoribonuclease activity GO:0004521 34 33 0,000 0,0177821 0,02214083 ! eye morphogenesis GO:0048592 38 33 0,000 0,0177821 0,02213311 ! embryonic organ development GO:0048568 36 33 0,000 0,0177821 0,0221254 ! monosaccharide biosynthetic process GO:0046364 35 33 0,000 0,0177821 0,02211769 ! cell junction organization GO:0034330 35 33 0,000 0,0177821 0,02210999 ! tissue remodeling GO:0048771 35 33 0,000 0,0177821 0,02210229 ! segmentation GO:0035282 34 33 0,000 0,0177821 0,0220946 ! steroid hormone receptor binding GO:0035258 33 33 0,000 0,0177821 0,02208692 ! positive regulation of gene-specific transcription GO:0043193 34 33 0,000 0,0177821 0,02207924 ! energy coupled proton transport, down electrochemical gradient GO:0015985 33 33 0,000 0,0177821 0,02207156 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 35 33 0,000 0,0177821 0,02206389 ! hormone biosynthetic process GO:0042446 33 33 0,000 0,0177821 0,02205623 ! androgen receptor signaling pathway GO:0030521 34 33 0,000 0,0177821 0,02204857 ! O-acyltransferase activity GO:0008374 33 33 0,000 0,0177821 0,02204092 ! response to xenobiotic stimulus GO:0009410 33 33 0,000 0,0177821 0,02203327 ! cellular amide metabolic process GO:0043603 34 34 0,000 0,01831661 0,02268769 ! sugar transmembrane transporter activity GO:0051119 34 34 0,000 0,01831661 0,02267982 GO:0015144|carbohydrate transmembrane transporter activity, ! neural tube development GO:0021915 36 34 0,000 0,01831661 0,02267196 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 34 0,000 0,01831661 0,0226641 ! neutral lipid metabolic process GO:0006638 35 34 0,000 0,01831661 0,02265625 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 34 34 0,000 0,01831661 0,02264841 ! telencephalon development GO:0021537 34 34 0,000 0,01831661 0,02264057 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 35 34 0,000 0,01831661 0,02263273 ! integral to Golgi membrane GO:0030173 34 34 0,000 0,01831661 0,02262491 ! collagen GO:0005581 35 34 0,000 0,01831661 0,02261708 ! DNA-directed RNA polymerase activity GO:0003899 35 34 0,000 0,01831661 0,02260926 GO:0034062|RNA polymerase activity, ! leukocyte chemotaxis GO:0030595 35 34 0,000 0,01831661 0,02260145 GO:0060326|cell chemotaxis, ! sodium channel activity GO:0005272 36 34 0,000 0,01831661 0,02259365 ! carboxypeptidase activity GO:0004180 35 34 0,000 0,01831661 0,02258584 ! spermatid development GO:0007286 34 34 0,000 0,01831661 0,02257805 ! BMP signaling pathway GO:0030509 35 34 0,000 0,01831661 0,02257026 ! specific RNA polymerase II transcription factor activity GO:0003704 35 34 0,000 0,01831661 0,02256247 ! positive regulation of DNA metabolic process GO:0051054 40 35 0,000 0,01885086 0,02321255 ! mitotic cell cycle checkpoint GO:0007093 35 35 0,000 0,01885086 0,02320455 ! regulation of intracellular protein transport GO:0033157 37 35 0,000 0,01885086 0,02319656 ! vesicle lumen GO:0031983 37 35 0,000 0,01885086 0,02318857 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! metanephros development GO:0001656 35 35 0,000 0,01885086 0,02318058 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 39 35 0,000 0,01885086 0,0231726 ! cytokine production GO:0001816 35 35 0,000 0,01885086 0,02316463 ! carbon-carbon lyase activity GO:0016830 35 35 0,000 0,01885086 0,02315666 ! embryonic pattern specification GO:0009880 36 35 0,000 0,01885086 0,0231487 ! regulation of metal ion transport GO:0010959 38 35 0,000 0,01885086 0,02314074 ! energy reserve metabolic process GO:0006112 36 35 0,000 0,01885086 0,02313279 ! metalloexopeptidase activity GO:0008235 36 35 0,000 0,01885086 0,02312484 ! protein serine/threonine phosphatase complex GO:0008287 38 35 0,000 0,01885086 0,0231169 ! phagocytosis GO:0006909 37 35 0,000 0,01885086 0,02310896 ! regulation of ARF protein signal transduction GO:0032012 40 35 0,000 0,01885086 0,02310103 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 37 35 0,000 0,01885086 0,02309311 ! ion transmembrane transport GO:0034220 35 35 0,000 0,01885086 0,02308519 ! neuropeptide receptor activity GO:0008188 35 35 0,000 0,01885086 0,02307727 ! oxygen binding GO:0019825 36 35 0,000 0,01885086 0,02306937 ! regulation of leukocyte mediated immunity GO:0002703 39 35 0,000 0,01885086 0,02306146 ! erythrocyte homeostasis GO:0034101 37 35 0,000 0,01885086 0,02305356 ! peripheral nervous system development GO:0007422 37 35 0,000 0,01885086 0,02304567 ! female gamete generation GO:0007292 38 35 0,000 0,01885086 0,02303778 ! polyol metabolic process GO:0019751 36 35 0,000 0,01885086 0,0230299 ! negative regulation of adenylate cyclase activity GO:0007194 38 36 0,000 0,01938485 0,02367418 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of hormone secretion GO:0046883 38 36 0,000 0,01938485 0,02366609 ! monocarboxylic acid binding GO:0033293 37 36 0,000 0,01938485 0,023658 ! polysaccharide biosynthetic process GO:0000271 36 36 0,000 0,01938485 0,02364992 ! regulation of axonogenesis GO:0050770 39 36 0,000 0,01938485 0,02364184 ! glycerol ether metabolic process GO:0006662 37 36 0,000 0,01938485 0,02363377 ! regulation of proteolysis GO:0030162 37 36 0,000 0,01938485 0,0236257 ! integral to endoplasmic reticulum membrane GO:0030176 36 36 0,000 0,01938485 0,02361764 ! regulation of adaptive immune response GO:0002819 40 36 0,000 0,01938485 0,02360959 ! oxidoreduction coenzyme metabolic process GO:0006733 37 36 0,000 0,01938485 0,02360154 ! isoprenoid metabolic process GO:0006720 37 36 0,000 0,01938485 0,02359349 ! spermatid differentiation GO:0048515 36 36 0,000 0,01938485 0,02358545 ! phosphoinositide biosynthetic process GO:0046489 38 36 0,000 0,01938485 0,02357742 ! ER to Golgi vesicle-mediated transport GO:0006888 36 36 0,000 0,01938485 0,02356939 ! condensed chromosome kinetochore GO:0000777 37 36 0,000 0,01938485 0,02356137 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 38 36 0,000 0,01938485 0,02355335 ! neuropeptide binding GO:0042923 36 36 0,000 0,01938485 0,02354534 ! organic anion transport GO:0015711 37 36 0,000 0,01938485 0,02353734 ! carbohydrate homeostasis GO:0033500 38 36 0,000 0,01938485 0,02352934 GO:0042593|glucose homeostasis, ! complement activation GO:0006956 39 36 0,000 0,01938485 0,02352134 ! antigen binding GO:0003823 36 36 0,000 0,01938485 0,02351335 ! extrinsic to plasma membrane GO:0019897 36 36 0,000 0,01938485 0,02350537 ! cytokinesis GO:0000910 40 36 0,000 0,01938485 0,02349739 ! coated pit GO:0005905 42 36 0,000 0,01938485 0,02348941 ! positive regulation of leukocyte proliferation GO:0070665 40 36 0,000 0,01938485 0,02348145 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein amino acid N-linked glycosylation GO:0006487 40 37 0,000 0,01991859 0,0241198 ! ribonucleoside metabolic process GO:0009119 43 37 0,000 0,01991859 0,02411162 ! DNA-dependent ATPase activity GO:0008094 39 37 0,000 0,01991859 0,02410345 ! regulation of T cell differentiation GO:0045580 41 37 0,000 0,01991859 0,02409529 ! biopolymer methylation GO:0043414 42 37 0,000 0,01991859 0,02408713 ! intrinsic to Golgi membrane GO:0031228 37 37 0,000 0,01991859 0,02407897 ! protein homooligomerization GO:0051260 38 37 0,000 0,01991859 0,02407083 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 38 37 0,000 0,01991859 0,02406268 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 41 37 0,000 0,01991859 0,02405455 ! regulation of T cell proliferation GO:0042129 41 37 0,000 0,01991859 0,02404641 ! multicellular organismal metabolic process GO:0044236 38 37 0,000 0,01991859 0,02403829 ! amino acid binding GO:0016597 40 37 0,000 0,01991859 0,02403017 ! maintenance of protein location GO:0045185 38 37 0,000 0,01991859 0,02402205 ! maintenance of location in cell GO:0051651 38 37 0,000 0,01991859 0,02401394 ! solute:hydrogen symporter activity GO:0015295 37 37 0,000 0,01991859 0,02400584 ! proton-transporting two-sector ATPase complex GO:0016469 37 37 0,000 0,01991859 0,02399774 ! ear morphogenesis GO:0042471 39 38 0,000 0,02045208 0,02463217 ! odontogenesis GO:0042476 40 38 0,000 0,02045208 0,02462386 ! organic ether metabolic process GO:0018904 39 38 0,000 0,02045208 0,02461556 ! alcohol biosynthetic process GO:0046165 40 38 0,000 0,02045208 0,02460727 ! monovalent inorganic cation homeostasis GO:0055067 39 38 0,000 0,02045208 0,02459898 ! positive regulation of DNA binding GO:0043388 39 38 0,000 0,02045208 0,0245907 ! B cell differentiation GO:0030183 40 38 0,000 0,02045208 0,02458242 ! clathrin coat GO:0030118 43 38 0,000 0,02045208 0,02457415 ! regulation of endocytosis GO:0030100 39 38 0,000 0,02045208 0,02456588 ! dorsal/ventral pattern formation GO:0009953 38 38 0,000 0,02045208 0,02455762 ! cell growth GO:0016049 40 38 0,000 0,02045208 0,02454937 ! positive regulation of defense response GO:0031349 38 38 0,000 0,02045208 0,02454112 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 38 0,000 0,02045208 0,02453288 ! condensed chromosome, centromeric region GO:0000779 39 38 0,000 0,02045208 0,02452464 ! learning GO:0007612 42 38 0,000 0,02045208 0,02451641 ! negative regulation of protein complex disassembly GO:0043242 40 38 0,000 0,02045208 0,02450818 ! monocarboxylic acid transport GO:0015718 39 38 0,000 0,02045208 0,02449996 ! endosome transport GO:0016197 40 38 0,000 0,02045208 0,02449174 ! hormone-mediated signaling GO:0009755 39 38 0,000 0,02045208 0,02448353 ! N-methyltransferase activity GO:0008170 42 38 0,000 0,02045208 0,02447533 ! cytosolic large ribosomal subunit GO:0022625 38 38 0,000 0,02045208 0,02446713 ! pigment metabolic process GO:0042440 42 38 0,000 0,02045208 0,02445893 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 38 38 0,000 0,02045208 0,02445074 ! RNA modification GO:0009451 39 38 0,000 0,02045208 0,02444256 ! regulation of nucleocytoplasmic transport GO:0046822 41 39 0,000 0,02098531 0,02507144 ! Notch signaling pathway GO:0007219 41 39 0,000 0,02098531 0,02506306 ! induction of apoptosis by extracellular signals GO:0008624 39 39 0,000 0,02098531 0,02505468 ! keratin filament GO:0045095 41 39 0,000 0,02098531 0,02504631 ! ER-Golgi intermediate compartment GO:0005793 42 39 0,000 0,02098531 0,02503794 ! peroxisomal membrane GO:0005778 40 39 0,000 0,02098531 0,02502957 GO:0031903|microbody membrane, ! mitochondrial respiratory chain complex I GO:0005747 39 39 0,000 0,02098531 0,02502122 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! actin filament binding GO:0051015 39 39 0,000 0,02098531 0,02501287 ! regulation of protein secretion GO:0050708 41 39 0,000 0,02098531 0,02500452 ! cis-trans isomerase activity GO:0016859 39 39 0,000 0,02098531 0,02499618 ! regulation of cell morphogenesis involved in differentiation GO:0010769 42 39 0,000 0,02098531 0,02498784 ! viral infectious cycle GO:0019058 39 39 0,000 0,02098531 0,02497952 ! mammary gland development GO:0030879 41 39 0,000 0,02098531 0,02497119 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 39 0,000 0,02098531 0,02496287 ! amine receptor activity GO:0008227 41 39 0,000 0,02098531 0,02495456 ! positive regulation of response to external stimulus GO:0032103 39 39 0,000 0,02098531 0,02494625 ! monosaccharide binding GO:0048029 39 39 0,000 0,02098531 0,02493795 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 39 39 0,000 0,02098531 0,02492966 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! phosphotransferase activity, phosphate group as acceptor GO:0016776 44 40 0,000 0,02151829 0,02555431 ! response to estrogen stimulus GO:0043627 41 40 0,000 0,02151829 0,02554581 ! peptide metabolic process GO:0006518 41 40 0,000 0,02151829 0,02553733 ! regulation of Rab protein signal transduction GO:0032483 41 40 0,000 0,02151829 0,02552884 GO:0032313|regulation of Rab GTPase activity, ! T cell differentiation GO:0030217 45 40 0,000 0,02151829 0,02552036 ! regulation of multicellular organism growth GO:0040014 42 40 0,000 0,02151829 0,02551189 ! regulation of gene expression, epigenetic GO:0040029 43 40 0,000 0,02151829 0,02550342 ! neuron migration GO:0001764 42 40 0,000 0,02151829 0,02549496 ! inositol or phosphatidylinositol kinase activity GO:0004428 42 40 0,000 0,02151829 0,0254865 ! structural constituent of muscle GO:0008307 43 40 0,000 0,02151829 0,02547805 ! feeding behavior GO:0007631 40 40 0,000 0,02151829 0,02546961 ! nucleus organization GO:0006997 40 40 0,000 0,02151829 0,02546117 ! positive regulation of cytokine biosynthetic process GO:0042108 41 40 0,000 0,02151829 0,02545274 ! sulfur compound biosynthetic process GO:0044272 41 40 0,000 0,02151829 0,02544431 ! inorganic anion transmembrane transporter activity GO:0015103 42 40 0,000 0,02151829 0,02543589 ! chromatin remodeling GO:0006338 43 40 0,000 0,02151829 0,02542747 ! activation of adenylate cyclase activity GO:0007190 42 41 0,000 0,02205101 0,02604835 ! positive regulation of binding GO:0051099 42 41 0,000 0,02205101 0,02603974 ! response to reactive oxygen species GO:0000302 43 41 0,000 0,02205101 0,02603113 ! solute:sodium symporter activity GO:0015370 41 41 0,000 0,02205101 0,02602253 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 44 41 0,000 0,02205101 0,02601393 GO:0046328|regulation of JNK cascade, ! mesenchymal cell development GO:0014031 43 41 0,000 0,02205101 0,02600534 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! heterocycle biosynthetic process GO:0018130 43 41 0,000 0,02205101 0,02599675 ! exonuclease activity GO:0004527 42 41 0,000 0,02205101 0,02598817 ! regulation of myeloid cell differentiation GO:0045637 43 41 0,000 0,02205101 0,0259796 ! positive regulation of cytokine production GO:0001819 42 41 0,000 0,02205101 0,02597103 ! positive regulation of protein transport GO:0051222 44 41 0,000 0,02205101 0,02596247 ! receptor-mediated endocytosis GO:0006898 43 41 0,000 0,02205101 0,02595391 ! regulation of neuron projection development GO:0010975 44 41 0,000 0,02205101 0,02594536 ! metal cluster binding GO:0051540 43 41 0,000 0,02205101 0,02593681 GO:0051536|iron-sulfur cluster binding, ! embryonic skeletal system morphogenesis GO:0048704 42 41 0,000 0,02205101 0,02592827 ! development of primary male sexual characteristics GO:0046546 41 41 0,000 0,02205101 0,02591974 ! double-strand break repair GO:0006302 41 41 0,000 0,02205101 0,02591121 ! Rab GTPase activator activity GO:0005097 42 41 0,000 0,02205101 0,02590269 ! RNA catabolic process GO:0006401 44 42 0,000 0,02258348 0,02651944 ! organellar ribosome GO:0000313 43 42 0,000 0,02258348 0,02651072 GO:0005761|mitochondrial ribosome, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 44 42 0,000 0,02258348 0,02650201 ! damaged DNA binding GO:0003684 42 42 0,000 0,02258348 0,02649331 ! MHC protein complex GO:0042611 42 42 0,000 0,02258348 0,02648461 ! regulation of epithelial cell proliferation GO:0050678 44 42 0,000 0,02258348 0,02647591 ! negative regulation of cell migration GO:0030336 44 42 0,000 0,02258348 0,02646722 ! icosanoid metabolic process GO:0006690 43 42 0,000 0,02258348 0,02645854 ! chemokine activity GO:0008009 42 42 0,000 0,02258348 0,02644986 ! ruffle GO:0001726 44 42 0,000 0,02258348 0,02644119 ! pigmentation GO:0043473 46 42 0,000 0,02258348 0,02643252 ! developmental growth GO:0048589 42 42 0,000 0,02258348 0,02642386 ! methylation GO:0032259 47 42 0,000 0,02258348 0,02641521 ! glycolysis GO:0006096 42 42 0,000 0,02258348 0,02640656 ! morphogenesis of embryonic epithelium GO:0016331 44 42 0,000 0,02258348 0,02639791 ! regulation of tube size GO:0035150 44 42 0,000 0,02258348 0,02638927 GO:0050880|regulation of blood vessel size, ! branching morphogenesis of a tube GO:0048754 43 42 0,000 0,02258348 0,02638064 ! general RNA polymerase II transcription factor activity GO:0016251 44 42 0,000 0,02258348 0,02637202 ! cellular amino acid derivative biosynthetic process GO:0042398 43 42 0,000 0,02258348 0,02636339 ! positive regulation of adenylate cyclase activity GO:0045762 44 43 0,000 0,0231157 0,02697587 ! transferase activity, transferring pentosyl groups GO:0016763 45 43 0,000 0,0231157 0,02696706 ! epithelial cell differentiation GO:0030855 45 43 0,000 0,0231157 0,02695825 ! detection of stimulus involved in sensory perception GO:0050906 43 43 0,000 0,0231157 0,02694945 ! sulfotransferase activity GO:0008146 44 43 0,000 0,0231157 0,02694066 ! cellular polysaccharide metabolic process GO:0044264 44 43 0,000 0,0231157 0,02693187 ! channel regulator activity GO:0016247 46 43 0,000 0,0231157 0,02692308 ! histone modification GO:0016570 44 43 0,000 0,0231157 0,0269143 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 45 43 0,000 0,0231157 0,02690553 ! synaptosome GO:0019717 47 43 0,000 0,0231157 0,02689676 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 45 44 0,000 0,02364766 0,02750678 ! platelet alpha granule GO:0031091 46 44 0,000 0,02364766 0,02749782 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 44 44 0,000 0,02364766 0,02748887 ! regulation of ossification GO:0030278 48 44 0,000 0,02364766 0,02747993 ! cell recognition GO:0008037 46 44 0,000 0,02364766 0,02747099 ! positive regulation of cyclase activity GO:0031281 45 44 0,000 0,02364766 0,02746205 ! regulation of lymphocyte differentiation GO:0045619 48 44 0,000 0,02364766 0,02745312 ! regulation of actin filament polymerization GO:0030833 45 44 0,000 0,02364766 0,0274442 ! cellular component disassembly GO:0022411 45 44 0,000 0,02364766 0,02743529 ! regulation of protein complex disassembly GO:0043244 46 44 0,000 0,02364766 0,02742638 ! regulation of ion transport GO:0043269 47 44 0,000 0,02364766 0,02741747 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 50 44 0,000 0,02364766 0,02740857 ! inner ear development GO:0048839 46 44 0,000 0,02364766 0,02739968 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 48 44 0,000 0,02364766 0,02739079 ! amino acid transmembrane transporter activity GO:0015171 44 44 0,000 0,02364766 0,02738191 ! negative regulation of immune system process GO:0002683 49 44 0,000 0,02364766 0,02737303 ! chemokine receptor binding GO:0042379 44 44 0,000 0,02364766 0,02736416 ! regulation of mast cell proliferation GO:0070666 48 44 0,000 0,02364766 0,0273553 ! regulation of gene-specific transcription GO:0032583 47 45 0,000 0,02417937 0,02796132 ! cellular amino acid biosynthetic process GO:0008652 47 45 0,000 0,02417937 0,02795227 ! nucleoside monophosphate biosynthetic process GO:0009124 50 45 0,000 0,02417937 0,02794322 ! positive regulation of lyase activity GO:0051349 46 45 0,000 0,02417937 0,02793418 ! regulation of neuron apoptosis GO:0043523 45 45 0,000 0,02417937 0,02792514 ! excretion GO:0007588 46 45 0,000 0,02417937 0,02791612 ! protein phosphatase regulator activity GO:0019888 49 45 0,000 0,02417937 0,02790709 ! JNK cascade GO:0007254 45 45 0,000 0,02417937 0,02789808 ! SH3/SH2 adaptor activity GO:0005070 48 45 0,000 0,02417937 0,02788907 ! regulation of cell shape GO:0008360 46 45 0,000 0,02417937 0,02788006 ! epithelial tube morphogenesis GO:0060562 47 45 0,000 0,02417937 0,02787106 ! microbody part GO:0044438 46 45 0,000 0,02417937 0,02786207 GO:0044439|peroxisomal part, ! auxiliary transport protein activity GO:0015457 50 46 0,000 0,02471083 0,02846528 ! ATP synthesis coupled electron transport GO:0042773 46 46 0,000 0,02471083 0,0284561 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! microtubule binding GO:0008017 49 46 0,000 0,02471083 0,02844693 ! regulation of inflammatory response GO:0050727 46 46 0,000 0,02471083 0,02843776 ! transport vesicle GO:0030133 49 46 0,000 0,02471083 0,0284286 ! glutamine family amino acid metabolic process GO:0009064 49 46 0,000 0,02471083 0,02841945 ! synapse organization GO:0050808 51 46 0,000 0,02471083 0,0284103 ! nuclear matrix GO:0016363 49 46 0,000 0,02471083 0,02840115 ! striated muscle contraction GO:0006941 49 46 0,000 0,02471083 0,02839201 ! unsaturated fatty acid metabolic process GO:0033559 47 46 0,000 0,02471083 0,02838288 ! antioxidant activity GO:0016209 47 46 0,000 0,02471083 0,02837376 ! activation of caspase activity GO:0006919 49 46 0,000 0,02471083 0,02836463 ! aging GO:0007568 48 46 0,000 0,02471083 0,02835552 ! male sex differentiation GO:0046661 46 46 0,000 0,02471083 0,02834641 ! coated vesicle membrane GO:0030662 49 46 0,000 0,02471083 0,02833731 ! covalent chromatin modification GO:0016569 47 46 0,000 0,02471083 0,02832821 ! RNA elongation from RNA polymerase II promoter GO:0006368 48 46 0,000 0,02471083 0,02831912 ! regulation of leukocyte proliferation GO:0070663 50 46 0,000 0,02471083 0,02831003 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! protein amino acid lipidation GO:0006497 50 47 0,000 0,02524203 0,02890933 ! stress-activated protein kinase signaling pathway GO:0031098 47 47 0,000 0,02524203 0,02890007 ! carbohydrate transport GO:0008643 47 47 0,000 0,02524203 0,0288908 ! proteasome complex GO:0000502 48 47 0,000 0,02524203 0,02888155 ! immunoglobulin mediated immune response GO:0016064 50 47 0,000 0,02524203 0,0288723 ! phosphatase regulator activity GO:0019208 51 47 0,000 0,02524203 0,02886305 ! vesicle organization GO:0016050 50 47 0,000 0,02524203 0,02885381 ! vascular process in circulatory system GO:0003018 49 47 0,000 0,02524203 0,02884458 ! cell cortex part GO:0044448 51 47 0,000 0,02524203 0,02883535 ! lipid modification GO:0030258 49 48 0,000 0,02577298 0,02943247 ! cytokine-mediated signaling pathway GO:0019221 49 48 0,000 0,02577298 0,02942306 ! morphogenesis of a branching structure GO:0001763 49 48 0,000 0,02577298 0,02941366 ! mitochondrial transport GO:0006839 49 48 0,000 0,02577298 0,02940426 ! viral reproductive process GO:0022415 52 48 0,000 0,02577298 0,02939487 ! leukocyte migration GO:0050900 49 48 0,000 0,02577298 0,02938548 ! neuromuscular process GO:0050905 49 48 0,000 0,02577298 0,0293761 ! gastrulation GO:0007369 50 48 0,000 0,02577298 0,02936673 ! detection of abiotic stimulus GO:0009582 48 48 0,000 0,02577298 0,02935736 ! heterocycle catabolic process GO:0046700 53 48 0,000 0,02577298 0,029348 ! B cell mediated immunity GO:0019724 51 48 0,000 0,02577298 0,02933864 ! transferase activity, transferring sulfur-containing groups GO:0016782 50 49 0,000 0,02630368 0,02993322 ! single-stranded DNA binding GO:0003697 49 49 0,000 0,02630368 0,02992368 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 54 49 0,000 0,02630368 0,02991416 ! intrinsic to endoplasmic reticulum membrane GO:0031227 50 49 0,000 0,02630368 0,02990463 ! ribonuclease activity GO:0004540 50 49 0,000 0,02630368 0,02989511 ! positive regulation of organelle organization GO:0010638 49 49 0,000 0,02630368 0,0298856 ! water-soluble vitamin metabolic process GO:0006767 50 49 0,000 0,02630368 0,0298761 ! negative regulation of cell motion GO:0051271 51 49 0,000 0,02630368 0,0298666 ! nucleosome GO:0000786 49 49 0,000 0,02630368 0,0298571 ! kinetochore GO:0000776 50 49 0,000 0,02630368 0,02984762 ! membrane fusion GO:0006944 51 49 0,000 0,02630368 0,02983813 ! endocrine system development GO:0035270 49 49 0,000 0,02630368 0,02982866 ! RNA elongation GO:0006354 51 49 0,000 0,02630368 0,02981919 ! glycosaminoglycan metabolic process GO:0030203 53 50 0,000 0,02683413 0,03041087 ! regulation of actin polymerization or depolymerization GO:0008064 51 50 0,000 0,02683413 0,03040123 ! basement membrane GO:0005604 51 50 0,000 0,02683413 0,03039158 ! regulation of intracellular transport GO:0032386 52 50 0,000 0,02683413 0,03038195 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,02683413 0,03037232 ! maintenance of location GO:0051235 51 50 0,000 0,02683413 0,03036269 ! nuclear periphery GO:0034399 53 50 0,000 0,02683413 0,03035308 ! cell redox homeostasis GO:0045454 51 50 0,000 0,02683413 0,03034347 ! integrin binding GO:0005178 53 50 0,000 0,02683413 0,03033386 ! regulation of DNA replication GO:0006275 56 50 0,000 0,02683413 0,03032426 ! amino acid activation GO:0043038 50 50 0,000 0,02683413 0,03031467 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of organelle localization GO:0051656 53 50 0,000 0,02683413 0,03030508 ! regulation of bone remodeling GO:0046850 55 51 0,000 0,02736432 0,03089408 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 52 51 0,000 0,02736432 0,03088432 ! late endosome GO:0005770 51 51 0,000 0,02736432 0,03087456 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 56 51 0,000 0,02736432 0,03086481 ! ligase activity, forming carbon-oxygen bonds GO:0016875 51 51 0,000 0,02736432 0,03085506 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! negative regulation of response to stimulus GO:0048585 55 51 0,000 0,02736432 0,03084532 ! skeletal muscle fiber development GO:0048741 54 51 0,000 0,02736432 0,03083559 ! lipoprotein biosynthetic process GO:0042158 54 51 0,000 0,02736432 0,03082586 ! heart morphogenesis GO:0003007 54 51 0,000 0,02736432 0,03081614 ! steroid hormone receptor activity GO:0003707 53 51 0,000 0,02736432 0,03080642 ! antiporter activity GO:0015297 52 51 0,000 0,02736432 0,03079671 ! respiratory electron transport chain GO:0022904 52 52 0,000 0,02789426 0,03138323 ! positive regulation of cell migration GO:0030335 55 52 0,000 0,02789426 0,03137335 ! Golgi-associated vesicle GO:0005798 55 52 0,000 0,02789426 0,03136347 ! sphingolipid metabolic process GO:0006665 53 52 0,000 0,02789426 0,0313536 ! cell maturation GO:0048469 55 52 0,000 0,02789426 0,03134373 ! regulation of protein polymerization GO:0032271 53 52 0,000 0,02789426 0,03133387 ! regulation of actin filament length GO:0030832 53 52 0,000 0,02789426 0,03132402 ! regulation of cell projection organization GO:0031344 55 52 0,000 0,02789426 0,03131417 ! chloride transport GO:0006821 53 52 0,000 0,02789426 0,03130433 ! positive regulation of caspase activity GO:0043280 55 52 0,000 0,02789426 0,0312945 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 55 52 0,000 0,02789426 0,03128467 ! regulation of muscle contraction GO:0006937 56 52 0,000 0,02789426 0,03127485 ! negative regulation of cytoskeleton organization GO:0051494 57 52 0,000 0,02789426 0,03126503 ! glucose catabolic process GO:0006007 52 52 0,000 0,02789426 0,03125522 ! generation of a signal involved in cell-cell signaling GO:0003001 54 52 0,000 0,02789426 0,03124542 ! small ribosomal subunit GO:0015935 52 52 0,000 0,02789426 0,03123562 ! cytokine receptor activity GO:0004896 53 52 0,000 0,02789426 0,03122583 ! activation of phospholipase C activity GO:0007202 55 53 0,000 0,02842394 0,0318088 GO:0010863|positive regulation of phospholipase C activity, ! nucleoside monophosphate metabolic process GO:0009123 58 53 0,000 0,02842394 0,03179884 ! nucleoside metabolic process GO:0009116 61 53 0,000 0,02842394 0,03178888 ! N-acetyltransferase activity GO:0008080 54 53 0,000 0,02842394 0,03177893 ! synaptic vesicle GO:0008021 57 53 0,000 0,02842394 0,03176898 ! pyridoxal phosphate binding GO:0030170 56 53 0,000 0,02842394 0,03175904 GO:0070279|vitamin B6 binding, ! viral reproduction GO:0016032 57 53 0,000 0,02842394 0,03174911 ! cell projection assembly GO:0030031 56 53 0,000 0,02842394 0,03173918 ! embryonic skeletal system development GO:0048706 54 53 0,000 0,02842394 0,03172926 ! proton transport GO:0015992 53 53 0,000 0,02842394 0,03171934 ! mRNA binding GO:0003729 55 53 0,000 0,02842394 0,03170943 ! single fertilization GO:0007338 55 53 0,000 0,02842394 0,03169953 ! axon GO:0030424 58 54 0,000 0,02895337 0,03227989 ! heat shock protein binding GO:0031072 54 54 0,000 0,02895337 0,03226982 ! regulation of neurotransmitter levels GO:0001505 60 54 0,000 0,02895337 0,03225975 ! double-stranded DNA binding GO:0003690 55 54 0,000 0,02895337 0,03224969 ! positive regulation of phospholipase activity GO:0010518 56 54 0,000 0,02895337 0,03223963 ! tRNA processing GO:0008033 55 54 0,000 0,02895337 0,03222958 ! regulation of cellular response to stress GO:0080135 57 54 0,000 0,02895337 0,03221954 ! growth factor receptor binding GO:0070851 56 54 0,000 0,02895337 0,0322095 ! regulation of protein catabolic process GO:0042176 57 54 0,000 0,02895337 0,03219947 ! DNA catabolic process GO:0006308 55 54 0,000 0,02895337 0,03218945 ! regulation of tissue remodeling GO:0034103 58 54 0,000 0,02895337 0,03217943 ! regulation of cellular component size GO:0032535 56 55 0,000 0,02948255 0,03275738 ! hydrogen transport GO:0006818 55 55 0,000 0,02948255 0,03274719 ! glycerophospholipid biosynthetic process GO:0046474 59 55 0,000 0,02948255 0,032737 ! nucleotide-excision repair GO:0006289 58 55 0,000 0,02948255 0,03272683 ! large ribosomal subunit GO:0015934 56 55 0,000 0,02948255 0,03271666 ! protein amino acid autophosphorylation GO:0046777 57 55 0,000 0,02948255 0,03270649 ! positive regulation of secretion GO:0051047 60 56 0,000 0,03001148 0,03328292 ! regulation of mitosis GO:0007088 56 56 0,000 0,03001148 0,03327259 GO:0051783|regulation of nuclear division, ! actin filament organization GO:0007015 59 56 0,000 0,03001148 0,03326226 ! regulation of phospholipase activity GO:0010517 58 56 0,000 0,03001148 0,03325194 ! coenzyme biosynthetic process GO:0009108 59 56 0,000 0,03001148 0,03324163 ! cellular amino acid catabolic process GO:0009063 59 56 0,000 0,03001148 0,03323132 ! cartilage development GO:0051216 59 56 0,000 0,03001148 0,03322102 ! regulation of protein complex assembly GO:0043254 57 56 0,000 0,03001148 0,03321072 ! receptor signaling protein serine/threonine kinase activity GO:0004702 58 56 0,000 0,03001148 0,03320044 ! mesoderm development GO:0007498 57 56 0,000 0,03001148 0,03319015 ! camera-type eye development GO:0043010 59 56 0,000 0,03001148 0,03317988 ! regulation of transcription factor activity GO:0051090 59 57 0,000 0,03054016 0,03375392 GO:0090046|regulation of transcription regulator activity, ! ear development GO:0043583 60 57 0,000 0,03054016 0,03374347 ! chromosome segregation GO:0007059 59 57 0,000 0,03054016 0,03373304 ! positive regulation of T cell activation GO:0050870 62 57 0,000 0,03054016 0,03372261 ! kidney development GO:0001822 60 57 0,000 0,03054016 0,03371218 ! positive regulation of lipase activity GO:0060193 59 57 0,000 0,03054016 0,03370176 ! integrin-mediated signaling pathway GO:0007229 61 57 0,000 0,03054016 0,03369135 ! adult behavior GO:0030534 60 57 0,000 0,03054016 0,03368095 ! steroid hormone receptor signaling pathway GO:0030518 58 57 0,000 0,03054016 0,03367055 ! myosin complex GO:0016459 59 57 0,000 0,03054016 0,03366016 ! regulation of angiogenesis GO:0045765 60 58 0,000 0,03106858 0,034232 ! lysosomal membrane GO:0005765 59 58 0,000 0,03106858 0,03422144 ! extracellular matrix organization GO:0030198 59 58 0,000 0,03106858 0,03421089 ! positive regulation of cell motion GO:0051272 61 58 0,000 0,03106858 0,03420034 ! homeostasis of number of cells GO:0048872 62 58 0,000 0,03106858 0,0341898 ! regulation of vesicle-mediated transport GO:0060627 60 58 0,000 0,03106858 0,03417927 ! detection of external stimulus GO:0009581 59 58 0,000 0,03106858 0,03416874 ! secondary metabolic process GO:0019748 59 58 0,000 0,03106858 0,03415822 ! dendrite GO:0030425 61 59 0,000 0,03159676 0,03472823 ! molecular adaptor activity GO:0060090 65 59 0,000 0,03159676 0,03471754 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 60 59 0,000 0,03159676 0,03470686 GO:0051213|dioxygenase activity, ! embryonic limb morphogenesis GO:0030326 63 59 0,000 0,03159676 0,03469619 GO:0035113|embryonic appendage morphogenesis, ! ubiquitin thiolesterase activity GO:0004221 62 59 0,000 0,03159676 0,03468553 ! regulation of heart contraction GO:0008016 62 59 0,000 0,03159676 0,03467487 ! copper ion binding GO:0005507 61 59 0,000 0,03159676 0,03466421 ! activation of immune response GO:0002253 68 59 0,000 0,03159676 0,03465357 ! aminoglycan metabolic process GO:0006022 62 59 0,000 0,03159676 0,03464293 ! amine transmembrane transporter activity GO:0005275 59 59 0,000 0,03159676 0,03463229 ! chromatin remodeling complex GO:0016585 61 59 0,000 0,03159676 0,03462167 ! cell soma GO:0043025 63 59 0,000 0,03159676 0,03461105 ! regulation of homeostatic process GO:0032844 68 59 0,000 0,03159676 0,03460043 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 61 60 0,000 0,03212468 0,03516775 ! occluding junction GO:0070160 60 60 0,000 0,03212468 0,03515698 GO:0005923|tight junction, ! regulation of lipid metabolic process GO:0019216 63 60 0,000 0,03212468 0,03514621 ! myeloid cell differentiation GO:0030099 64 60 0,000 0,03212468 0,03513544 ! oxygen and reactive oxygen species metabolic process GO:0006800 60 60 0,000 0,03212468 0,03512468 ! regulation of cytokine biosynthetic process GO:0042035 63 60 0,000 0,03212468 0,03511393 ! lymphocyte mediated immunity GO:0002449 63 60 0,000 0,03212468 0,03510319 ! chloride channel activity GO:0005254 61 60 0,000 0,03212468 0,03509245 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 62 61 0,000 0,03265234 0,03565796 ! cell cycle checkpoint GO:0000075 64 61 0,000 0,03265234 0,03564706 ! fertilization GO:0009566 64 61 0,000 0,03265234 0,03563616 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 65 61 0,000 0,03265234 0,03562527 ! protein maturation by peptide bond cleavage GO:0051605 64 61 0,000 0,03265234 0,03561439 ! regulation of immune effector process GO:0002697 65 61 0,000 0,03265234 0,03560352 ! amine catabolic process GO:0009310 68 62 0,000 0,03317976 0,03616756 ! phosphoinositide metabolic process GO:0030384 66 62 0,000 0,03317976 0,03615652 ! glycerolipid biosynthetic process GO:0045017 66 62 0,000 0,03317976 0,03614549 ! coated membrane GO:0048475 67 62 0,000 0,03317976 0,03613447 GO:0030117|membrane coat, ! hexose catabolic process GO:0019320 63 62 0,000 0,03317976 0,03612345 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 63 62 0,000 0,03317976 0,03611244 ! extracellular ligand-gated ion channel activity GO:0005230 67 62 0,000 0,03317976 0,03610144 ! germ cell development GO:0007281 62 62 0,000 0,03317976 0,03609044 ! ligand-dependent nuclear receptor activity GO:0004879 65 62 0,000 0,03317976 0,03607945 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 70 63 0,000 0,03370692 0,03664153 ! mitochondrial respiratory chain GO:0005746 65 63 0,000 0,03370692 0,03663038 ! negative regulation of ligase activity GO:0051352 64 63 0,000 0,03370692 0,03661924 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein oligomerization GO:0051259 64 63 0,000 0,03370692 0,0366081 ! transition metal ion transport GO:0000041 65 63 0,000 0,03370692 0,03659697 ! appendage morphogenesis GO:0035107 67 63 0,000 0,03370692 0,03658584 GO:0035108|limb morphogenesis, ! activation of MAPK activity GO:0000187 69 63 0,000 0,03370692 0,03657473 ! cellular defense response GO:0006968 64 63 0,000 0,03370692 0,03656362 ! B cell activation GO:0042113 66 63 0,000 0,03370692 0,03655251 ! antigen processing and presentation GO:0019882 64 63 0,000 0,03370692 0,03654142 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 65 63 0,000 0,03370692 0,03653033 ! microtubule motor activity GO:0003777 67 63 0,000 0,03370692 0,03651924 ! intracellular receptor-mediated signaling pathway GO:0030522 64 63 0,000 0,03370692 0,03650817 ! organelle localization GO:0051640 66 63 0,000 0,03370692 0,0364971 ! transforming growth factor beta receptor signaling pathway GO:0007179 67 64 0,000 0,03423384 0,03705639 ! lung development GO:0030324 65 64 0,000 0,03423384 0,03704516 ! respiratory chain GO:0070469 66 64 0,000 0,03423384 0,03703394 ! developmental maturation GO:0021700 67 64 0,000 0,03423384 0,03702272 ! amino acid transport GO:0006865 64 64 0,000 0,03423384 0,03701152 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 66 64 0,000 0,03423384 0,03700031 ! anion channel activity GO:0005253 65 64 0,000 0,03423384 0,03698912 ! cellular hormone metabolic process GO:0034754 65 65 0,000 0,0347605 0,03754681 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 65 0,000 0,0347605 0,03753545 ! negative regulation of cell growth GO:0030308 68 65 0,000 0,0347605 0,03752411 ! nuclear pore GO:0005643 69 65 0,000 0,0347605 0,03751277 ! regulation of MAPKKK cascade GO:0043408 72 65 0,000 0,0347605 0,03750143 ! regulation of lipase activity GO:0060191 67 65 0,000 0,0347605 0,03749011 ! adaptive immune response GO:0002250 68 65 0,000 0,0347605 0,03747879 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 69 65 0,000 0,0347605 0,03746747 GO:0060173|limb development, ! skeletal system morphogenesis GO:0048705 66 65 0,000 0,0347605 0,03745617 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 67 65 0,000 0,0347605 0,03744487 ! lipoprotein metabolic process GO:0042157 68 65 0,000 0,0347605 0,03743358 ! DNA-dependent DNA replication GO:0006261 66 65 0,000 0,0347605 0,03742229 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 71 66 0,000 0,03528691 0,03797756 ! endoplasmic reticulum lumen GO:0005788 66 66 0,000 0,03528691 0,03796612 ! urogenital system development GO:0001655 69 66 0,000 0,03528691 0,03795469 ! response to steroid hormone stimulus GO:0048545 69 66 0,000 0,03528691 0,03794326 ! diacylglycerol binding GO:0019992 71 66 0,000 0,03528691 0,03793184 ! amine binding GO:0043176 70 66 0,000 0,03528691 0,03792042 ! acetyltransferase activity GO:0016407 68 66 0,000 0,03528691 0,03790901 ! negative regulation of cell size GO:0045792 70 67 0,000 0,03581307 0,0384627 ! respiratory tube development GO:0030323 68 67 0,000 0,03581307 0,03845113 ! mRNA transport GO:0051028 70 67 0,000 0,03581307 0,03843958 ! intracellular protein transmembrane transport GO:0065002 70 67 0,000 0,03581307 0,03842803 ! tubulin binding GO:0015631 70 67 0,000 0,03581307 0,03841648 ! positive regulation of lymphocyte activation GO:0051251 72 67 0,000 0,03581307 0,03840495 ! activation of protein kinase activity GO:0032147 70 67 0,000 0,03581307 0,03839342 ! Ras GTPase binding GO:0017016 70 67 0,000 0,03581307 0,03838189 ! humoral immune response GO:0006959 70 67 0,000 0,03581307 0,03837038 ! nuclear hormone receptor binding GO:0035257 68 67 0,000 0,03581307 0,03835887 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 69 67 0,000 0,03581307 0,03834737 ! ubiquitin ligase complex GO:0000151 71 67 0,000 0,03581307 0,03833587 ! nucleosome assembly GO:0006334 69 67 0,000 0,03581307 0,03832438 ! transcription initiation from RNA polymerase II promoter GO:0006367 71 67 0,000 0,03581307 0,0383129 ! muscle cell differentiation GO:0042692 68 68 0,000 0,03633898 0,03886388 ! fatty acid biosynthetic process GO:0006633 70 68 0,000 0,03633898 0,03885224 ! protein import into nucleus GO:0006606 72 68 0,000 0,03633898 0,03884061 ! lymphocyte differentiation GO:0030098 75 68 0,000 0,03633898 0,03882899 ! protein-DNA complex GO:0032993 69 68 0,000 0,03633898 0,03881738 ! learning or memory GO:0007611 72 68 0,000 0,03633898 0,03880577 ! chloride ion binding GO:0031404 70 68 0,000 0,03633898 0,03879417 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 71 68 0,000 0,03633898 0,03878257 ! chromatin assembly GO:0031497 70 68 0,000 0,03633898 0,03877099 ! leukocyte mediated immunity GO:0002443 71 68 0,000 0,03633898 0,03875941 ! extrinsic to membrane GO:0019898 68 68 0,000 0,03633898 0,03874783 ! calcium channel activity GO:0005262 73 68 0,000 0,03633898 0,03873627 ! respiratory system development GO:0060541 69 68 0,000 0,03633898 0,03872471 ! N-acyltransferase activity GO:0016410 69 68 0,000 0,03633898 0,03871315 ! eye development GO:0001654 74 69 0,000 0,03686463 0,03926144 ! positive regulation of ligase activity GO:0051351 71 69 0,000 0,03686463 0,03924974 ! sarcomere GO:0030017 75 69 0,000 0,03686463 0,03923804 ! cAMP-mediated signaling GO:0019933 72 69 0,000 0,03686463 0,03922634 ! axon guidance GO:0007411 74 69 0,000 0,03686463 0,03921466 ! focal adhesion GO:0005925 75 69 0,000 0,03686463 0,03920298 ! regulation of DNA binding GO:0051101 72 70 0,000 0,03739004 0,03974988 ! carboxylic acid transmembrane transporter activity GO:0046943 71 70 0,000 0,03739004 0,03973805 ! early endosome GO:0005769 79 70 0,000 0,03739004 0,03972622 ! response to hypoxia GO:0001666 76 70 0,000 0,03739004 0,03971441 ! nuclear import GO:0051170 74 70 0,000 0,03739004 0,0397026 ! female pregnancy GO:0007565 71 70 0,000 0,03739004 0,0396908 ! cytosolic ribosome GO:0022626 70 70 0,000 0,03739004 0,039679 ! cell-matrix adhesion GO:0007160 76 71 0,000 0,0379152 0,04022435 ! FAD binding GO:0050660 72 71 0,000 0,0379152 0,0402124 ! response to oxygen levels GO:0070482 77 71 0,000 0,0379152 0,04020047 ! mitochondrial outer membrane GO:0005741 75 71 0,000 0,0379152 0,04018853 ! defense response to bacterium GO:0042742 71 71 0,000 0,0379152 0,04017661 ! steroid biosynthetic process GO:0006694 72 71 0,000 0,0379152 0,04016469 ! monosaccharide catabolic process GO:0046365 72 71 0,000 0,0379152 0,04015278 ! regulation of synaptic transmission GO:0050804 73 71 0,000 0,0379152 0,04014087 ! neurotransmitter transport GO:0006836 73 71 0,000 0,0379152 0,04012898 ! organic acid transmembrane transporter activity GO:0005342 72 71 0,000 0,0379152 0,04011709 ! phospholipase activity GO:0004620 75 71 0,000 0,0379152 0,0401052 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 75 71 0,000 0,0379152 0,04009333 ! cell projection part GO:0044463 75 71 0,000 0,0379152 0,04008146 ! amine biosynthetic process GO:0009309 75 72 0,000 0,0384401 0,04062433 ! meiosis GO:0007126 73 72 0,000 0,0384401 0,04061231 GO:0051327|M phase of meiotic cell cycle, ! elevation of cytosolic calcium ion concentration GO:0007204 77 72 0,000 0,0384401 0,0406003 ! acute inflammatory response GO:0002526 76 72 0,000 0,0384401 0,04058829 ! cholesterol metabolic process GO:0008203 74 72 0,000 0,0384401 0,04057629 ! lipid transporter activity GO:0005319 77 72 0,000 0,0384401 0,0405643 ! regulation of ubiquitin-protein ligase activity GO:0051438 74 72 0,000 0,0384401 0,04055232 ! cell-substrate adherens junction GO:0005924 78 72 0,000 0,0384401 0,04054034 ! negative regulation of transport GO:0051051 74 73 0,000 0,03896476 0,04108153 ! vacuolar membrane GO:0005774 74 73 0,000 0,03896476 0,0410694 ! meiotic cell cycle GO:0051321 75 73 0,000 0,03896476 0,04105729 ! negative regulation of organelle organization GO:0010639 78 73 0,000 0,03896476 0,04104517 ! regulation of protein transport GO:0051223 77 73 0,000 0,03896476 0,04103307 GO:0070201|regulation of establishment of protein localization, ! exopeptidase activity GO:0008238 78 73 0,000 0,03896476 0,04102097 ! cytosolic calcium ion homeostasis GO:0051480 78 73 0,000 0,03896476 0,04100888 ! hormone receptor binding GO:0051427 75 73 0,000 0,03896476 0,0409968 ! nucleosome organization GO:0034728 76 74 0,000 0,03948916 0,04153631 ! neuropeptide signaling pathway GO:0007218 79 74 0,000 0,03948916 0,04152408 ! pore complex GO:0046930 78 74 0,000 0,03948916 0,04151186 ! protein localization in nucleus GO:0034504 78 74 0,000 0,03948916 0,04149964 ! myofibril GO:0030016 80 74 0,000 0,03948916 0,04148743 ! regulation of blood pressure GO:0008217 76 74 0,000 0,03948916 0,04147523 ! apical junction complex GO:0043296 74 74 0,000 0,03948916 0,04146304 ! cellular carbohydrate catabolic process GO:0044275 75 74 0,000 0,03948916 0,04145085 ! membrane raft GO:0045121 78 74 0,000 0,03948916 0,04143867 ! cellular response to hormone stimulus GO:0032870 81 74 0,000 0,03948916 0,04142649 ! serine-type endopeptidase inhibitor activity GO:0004867 75 74 0,000 0,03948916 0,04141433 ! nuclear chromosome part GO:0044454 76 74 0,000 0,03948916 0,04140217 ! response to drug GO:0042493 77 75 0,000 0,04001331 0,0419394 ! small GTPase binding GO:0031267 78 75 0,000 0,04001331 0,04192709 ! regulation of catabolic process GO:0009894 80 75 0,000 0,04001331 0,0419148 ! cell-substrate junction GO:0030055 82 75 0,000 0,04001331 0,0419025 ! positive regulation of cell activation GO:0050867 80 75 0,000 0,04001331 0,04189022 GO:0002696|positive regulation of leukocyte activation, ! membrane lipid biosynthetic process GO:0046467 77 75 0,000 0,04001331 0,04187794 ! phosphoinositide-mediated signaling GO:0048015 79 75 0,000 0,04001331 0,04186567 ! tube morphogenesis GO:0035239 79 75 0,000 0,04001331 0,04185341 ! cellular lipid catabolic process GO:0044242 77 75 0,000 0,04001331 0,04184115 ! cysteine-type endopeptidase activity GO:0004197 75 75 0,000 0,04001331 0,0418289 ! structural constituent of cytoskeleton GO:0005200 81 75 0,000 0,04001331 0,04181666 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 80 76 0,000 0,04053722 0,04235178 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 76 76 0,000 0,04053722 0,0423394 ! regulation of ligase activity GO:0051340 78 76 0,000 0,04053722 0,04232702 ! vitamin metabolic process GO:0006766 77 76 0,000 0,04053722 0,04231464 ! inorganic anion transport GO:0015698 78 76 0,000 0,04053722 0,04230228 ! chromosome, centromeric region GO:0000775 78 76 0,000 0,04053722 0,04228992 ! apicolateral plasma membrane GO:0016327 76 76 0,000 0,04053722 0,04227757 ! T cell activation GO:0042110 82 76 0,000 0,04053722 0,04226523 ! digestion GO:0007586 80 76 0,000 0,04053722 0,04225289 ! cell-substrate adhesion GO:0031589 81 76 0,000 0,04053722 0,04224056 ! cilium GO:0005929 77 76 0,000 0,04053722 0,04222824 ! contractile fiber part GO:0044449 82 76 0,000 0,04053722 0,04221592 ! regulation of adenylate cyclase activity GO:0045761 80 77 0,000 0,04106087 0,04274879 ! nuclear speck GO:0016607 80 77 0,000 0,04106087 0,04273633 ! G-protein-coupled receptor binding GO:0001664 78 77 0,000 0,04106087 0,04272388 ! endonuclease activity GO:0004519 80 77 0,000 0,04106087 0,04271144 ! regulation of transmission of nerve impulse GO:0051969 79 77 0,000 0,04106087 0,042699 ! hydrogen ion transmembrane transporter activity GO:0015078 78 77 0,000 0,04106087 0,04268657 ! extracellular matrix structural constituent GO:0005201 80 77 0,000 0,04106087 0,04267414 ! vacuolar part GO:0044437 78 77 0,000 0,04106087 0,04266173 ! thiolester hydrolase activity GO:0016790 81 78 0,000 0,04158427 0,04319297 ! potassium channel complex GO:0034705 81 78 0,000 0,04158427 0,04318041 GO:0008076|voltage-gated potassium channel complex, ! cofactor biosynthetic process GO:0051188 81 78 0,000 0,04158427 0,04316786 ! blood coagulation GO:0007596 81 78 0,000 0,04158427 0,04315531 GO:0050817|coagulation, ! phospholipid biosynthetic process GO:0008654 83 79 0,000 0,04210742 0,04368553 ! biogenic amine metabolic process GO:0006576 85 79 0,000 0,04210742 0,04367285 ! phosphoric diester hydrolase activity GO:0008081 82 79 0,000 0,04210742 0,04366017 ! positive regulation of MAP kinase activity GO:0043406 85 79 0,000 0,04210742 0,04364749 ! regulation of cyclase activity GO:0031279 82 79 0,000 0,04210742 0,04363483 ! regulation of neuron differentiation GO:0045664 82 79 0,000 0,04210742 0,04362217 ! regulation of T cell activation GO:0050863 84 79 0,000 0,04210742 0,04360952 ! regulation of cAMP biosynthetic process GO:0030817 82 79 0,000 0,04210742 0,04359687 ! exocytosis GO:0006887 81 79 0,000 0,04210742 0,04358423 ! nitrogen compound catabolic process GO:0044270 89 79 0,000 0,04210742 0,04357161 ! regulation of protein localization GO:0032880 83 79 0,000 0,04210742 0,04355898 ! regulation of DNA metabolic process GO:0051052 90 80 0,000 0,04263033 0,04408714 ! alcohol catabolic process GO:0046164 83 80 0,000 0,04263033 0,04407438 ! GTPase binding GO:0051020 83 80 0,000 0,04263033 0,04406162 ! regulation of cell cycle process GO:0010564 84 80 0,000 0,04263033 0,04404887 ! negative regulation of growth GO:0045926 84 80 0,000 0,04263033 0,04403613 ! regulation of lyase activity GO:0051339 83 80 0,000 0,04263033 0,04402339 ! ATP biosynthetic process GO:0006754 85 80 0,000 0,04263033 0,04401067 ! one-carbon metabolic process GO:0006730 87 80 0,000 0,04263033 0,04399795 ! monooxygenase activity GO:0004497 82 80 0,000 0,04263033 0,04398523 ! condensed chromosome GO:0000793 82 80 0,000 0,04263033 0,04397253 ! contractile fiber GO:0043292 86 80 0,000 0,04263033 0,04395983 ! protein ubiquitination GO:0016567 86 80 0,000 0,04263033 0,04394714 ! ossification GO:0001503 85 81 0,000 0,04315298 0,0444731 ! cellular carbohydrate biosynthetic process GO:0034637 83 81 0,000 0,04315298 0,04446027 ! sterol metabolic process GO:0016125 83 81 0,000 0,04315298 0,04444744 ! regulation of cAMP metabolic process GO:0030814 84 81 0,000 0,04315298 0,04443463 ! protein binding, bridging GO:0030674 86 81 0,000 0,04315298 0,04442182 ! regulation of neurological system process GO:0031644 83 81 0,000 0,04315298 0,04440902 ! protein transporter activity GO:0008565 85 82 0,000 0,04367538 0,04493368 ! positive regulation of immune response GO:0050778 91 82 0,000 0,04367538 0,04492073 ! regulation of defense response GO:0031347 82 82 0,000 0,04367538 0,0449078 ! bone development GO:0060348 86 82 0,000 0,04367538 0,04489487 ! carboxylesterase activity GO:0004091 86 82 0,000 0,04367538 0,04488195 ! transcription initiation GO:0006352 86 82 0,000 0,04367538 0,04486904 ! organelle outer membrane GO:0031968 87 83 0,000 0,04419754 0,04539241 ! SH3 domain binding GO:0017124 97 83 0,000 0,04419754 0,04537936 ! hemostasis GO:0007599 86 83 0,000 0,04419754 0,04536631 ! oxidative phosphorylation GO:0006119 83 83 0,000 0,04419754 0,04535328 ! heparin binding GO:0008201 90 83 0,000 0,04419754 0,04534025 ! amine transport GO:0015837 83 83 0,000 0,04419754 0,04532723 ! extracellular matrix part GO:0044420 85 83 0,000 0,04419754 0,04531421 ! phosphoinositide binding GO:0035091 90 83 0,000 0,04419754 0,04530121 ! regulation of nucleotide biosynthetic process GO:0030808 87 84 0,000 0,04471944 0,04582299 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 85 84 0,000 0,04471944 0,04580985 GO:0010498|proteasomal protein catabolic process, ! Ras GTPase activator activity GO:0005099 89 84 0,000 0,04471944 0,04579671 ! perinuclear region of cytoplasm GO:0048471 91 85 0,000 0,0452411 0,04631765 ! cellular respiration GO:0045333 85 85 0,000 0,0452411 0,04630437 ! transmembrane receptor protein kinase activity GO:0019199 88 85 0,000 0,0452411 0,0462911 ! outer membrane GO:0019867 89 85 0,000 0,0452411 0,04627784 ! DNA recombination GO:0006310 86 85 0,000 0,0452411 0,04626459 ! neurotransmitter receptor activity GO:0030594 86 85 0,000 0,0452411 0,04625135 ! leukocyte differentiation GO:0002521 95 86 0,000 0,0457625 0,04677101 ! Golgi vesicle transport GO:0048193 86 86 0,000 0,0457625 0,04675762 ! pigment granule GO:0048770 90 86 0,000 0,0457625 0,04674425 GO:0042470|melanosome, ! neurotransmitter binding GO:0042165 88 86 0,000 0,0457625 0,04673088 ! anion binding GO:0043168 89 86 0,000 0,0457625 0,04671752 ! UDP-glycosyltransferase activity GO:0008194 91 86 0,000 0,0457625 0,04670417 ! spindle GO:0005819 89 87 0,000 0,04628366 0,04722255 ! microtubule cytoskeleton organization GO:0000226 92 87 0,000 0,04628366 0,04720907 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 93 87 0,000 0,04628366 0,04719559 ! regulation of cyclic nucleotide metabolic process GO:0030799 90 87 0,000 0,04628366 0,04718211 ! protein processing GO:0016485 92 87 0,000 0,04628366 0,04716865 ! ATP-dependent helicase activity GO:0008026 92 88 0,000 0,04680457 0,04768591 GO:0070035|purine NTP-dependent helicase activity, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 89 88 0,000 0,04680457 0,04767231 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 89 88 0,000 0,04680457 0,04765871 ! skeletal muscle tissue development GO:0007519 92 88 0,000 0,04680457 0,04764513 GO:0060538|skeletal muscle organ development, ! lipase activity GO:0016298 92 88 0,000 0,04680457 0,04763155 ! detection of stimulus GO:0051606 90 88 0,000 0,04680457 0,04761798 ! carboxylic acid catabolic process GO:0046395 93 89 0,000 0,04732522 0,04813397 GO:0016054|organic acid catabolic process, ! sulfur metabolic process GO:0006790 90 89 0,000 0,04732522 0,04812027 ! negative regulation of multicellular organismal process GO:0051241 93 89 0,000 0,04732522 0,04810657 ! regulation of binding GO:0051098 93 90 0,000 0,04784563 0,04862173 ! intermediate filament GO:0005882 92 90 0,000 0,04784563 0,0486079 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 95 90 0,000 0,04784563 0,04859407 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! nuclear membrane GO:0031965 92 90 0,000 0,04784563 0,04858025 ! external side of plasma membrane GO:0009897 99 90 0,000 0,04784563 0,04856645 ! growth factor binding GO:0019838 92 90 0,000 0,04784563 0,04855264 ! regulation of nucleotide metabolic process GO:0006140 93 90 0,000 0,04784563 0,04853885 ! adherens junction GO:0005912 96 90 0,000 0,04784563 0,04852507 ! ATP metabolic process GO:0046034 96 91 0,000 0,04836579 0,04903869 ! homophilic cell adhesion GO:0007156 93 91 0,000 0,04836579 0,04902477 ! ribonucleoside triphosphate biosynthetic process GO:0009201 97 91 0,000 0,04836579 0,04901085 ! protein modification by small protein conjugation GO:0032446 98 91 0,000 0,04836579 0,04899695 ! forebrain development GO:0030900 95 91 0,000 0,04836579 0,04898305 ! carbohydrate biosynthetic process GO:0016051 93 91 0,000 0,04836579 0,04896917 ! apical plasma membrane GO:0016324 96 91 0,000 0,04836579 0,04895529 ! intermediate filament cytoskeleton GO:0045111 93 91 0,000 0,04836579 0,04894141 ! structure-specific DNA binding GO:0043566 93 92 0,000 0,04888571 0,0494535 ! angiogenesis GO:0001525 95 92 0,000 0,04888571 0,0494395 ! glycerophospholipid metabolic process GO:0006650 98 92 0,000 0,04888571 0,0494255 ! nucleoside triphosphate biosynthetic process GO:0009142 98 92 0,000 0,04888571 0,04941151 ! clathrin-coated vesicle GO:0030136 100 92 0,000 0,04888571 0,04939753 ! gland development GO:0048732 95 92 0,000 0,04888571 0,04938355 ! DNA packaging GO:0006323 94 92 0,000 0,04888571 0,04936959 ! anatomical structure homeostasis GO:0060249 96 93 0,000 0,04940537 0,04988029 ! receptor complex GO:0043235 97 93 0,000 0,04940537 0,04986619 ! voltage-gated potassium channel activity GO:0005249 99 93 0,000 0,04940537 0,0498521 ! hormone metabolic process GO:0042445 96 93 0,000 0,04940537 0,04983802 ! translational elongation GO:0006414 97 94 0,000 0,04992478 0,05034776 ! nucleotidyltransferase activity GO:0016779 96 94 0,000 0,04992478 0,05033354 ! metalloendopeptidase activity GO:0004222 105 94 0,000 0,04992478 0,05031934 ! carbohydrate catabolic process GO:0016052 95 94 0,000 0,04992478 0,05030514 ! protein maturation GO:0051604 99 94 0,000 0,04992478 0,05029095 ! solute:cation symporter activity GO:0015294 95 94 0,000 0,04992478 0,05027676 ! in utero embryonic development GO:0001701 97 95 0,000 0,05044395 0,05078527 ! regulation of lymphocyte activation GO:0051249 100 95 0,000 0,05044395 0,05077096 ! carboxylic acid binding GO:0031406 99 95 0,000 0,05044395 0,05075665 ! regulation of response to external stimulus GO:0032101 97 95 0,000 0,05044395 0,05074235 ! response to virus GO:0009615 102 95 0,000 0,05044395 0,05072806 ! integral to organelle membrane GO:0031301 96 96 0,000 0,05096287 0,05123548 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 97 96 0,000 0,05096287 0,05122106 ! cell fate commitment GO:0045165 98 96 0,000 0,05096287 0,05120664 ! microtubule associated complex GO:0005875 104 97 0,000 0,05148154 0,05171324 ! peptidyl-amino acid modification GO:0018193 99 97 0,000 0,05148154 0,0516987 ! anchoring junction GO:0070161 103 97 0,000 0,05148154 0,05168417 ! unfolded protein binding GO:0051082 100 98 0,000 0,05199996 0,05218996 ! polysaccharide metabolic process GO:0005976 102 98 0,000 0,05199996 0,05217529 ! protein modification by small protein conjugation or removal GO:0070647 105 98 0,000 0,05199996 0,05216064 ! chromatin binding GO:0003682 102 99 0,000 0,05251814 0,05266562 ! nuclear chromosome GO:0000228 102 99 0,000 0,05251814 0,05265083 ! protein C-terminus binding GO:0008022 106 99 0,000 0,05251814 0,05263606 ! anterior/posterior pattern formation GO:0009952 102 99 0,000 0,05251814 0,05262129 ! Ras protein signal transduction GO:0007265 105 99 0,000 0,05251814 0,05260653 ! electron transport chain GO:0022900 102 100 0,000 0,05303606 0,05311043 ! tRNA metabolic process GO:0006399 101 100 0,000 0,05303606 0,05309554 ! protein polymerization GO:0051258 114 100 0,000 0,05303606 0,05308066 ! cytokine binding GO:0019955 101 100 0,000 0,05303606 0,05306578 ! regulation of cell morphogenesis GO:0022604 104 100 0,000 0,05303606 0,05305092 ! chromatin assembly or disassembly GO:0006333 104 100 0,000 0,05303606 0,05303606