pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/8607-10-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Ras protein signal transduction GO:0007265 69 67 3,000 2,576E-06 4,747E-03 ! keratinocyte differentiation GO:0030216 28 28 2,000 9,748E-06 8,983E-03 ! epidermal cell differentiation GO:0009913 31 31 2,000 1,334E-05 8,195E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 1,000 2,318E-05 0,01068088 ! regulation of Rac protein signal transduction GO:0035020 5 5 1,000 2,318E-05 8,545E-03 ! positive regulation of cell growth GO:0030307 6 6 1,000 3,474E-05 0,01067157 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 1,000 3,474E-05 9,147E-03 ! keratinocyte proliferation GO:0043616 7 7 1,000 4,86E-05 0,01119537 ! visual behavior GO:0007632 7 7 1,000 4,86E-05 9,951E-03 GO:0008542|visual learning, ! embryonic hindlimb morphogenesis GO:0035116 8 8 1,000 6,474E-05 0,01193131 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 1,000 6,474E-05 0,01084665 ! chromatin silencing GO:0006342 8 8 1,000 6,474E-05 9,943E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 6,474E-05 9,178E-03 ! positive regulation of cell size GO:0045793 9 9 1,000 8,316E-05 0,01094777 ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 1,000 8,316E-05 0,01021792 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 1,000 8,316E-05 9,579E-03 ! negative regulation of caspase activity GO:0043154 9 9 1,000 8,316E-05 9,016E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,039E-04 0,01063438 ! epidermis morphogenesis GO:0048730 10 10 1,000 1,039E-04 0,01007467 ! skin development GO:0043588 11 11 1,000 1,268E-04 0,01168761 ! hindbrain development GO:0030902 11 11 1,000 1,268E-04 0,01113106 ! hindlimb morphogenesis GO:0035137 12 12 1,000 1,521E-04 0,012739 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 1,521E-04 0,01218513 ! osteoblast differentiation GO:0001649 12 12 1,000 1,521E-04 0,01167742 ! cell fate determination GO:0001709 12 12 1,000 1,521E-04 0,01121032 ! cell aging GO:0007569 13 13 1,000 1,796E-04 0,01272789 ! blastocyst development GO:0001824 13 13 1,000 1,796E-04 0,01225648 ! striated muscle cell differentiation GO:0051146 16 15 1,000 2,413E-04 0,01588211 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 2,413E-04 0,01533445 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 2,755E-04 0,01692614 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of synaptic plasticity GO:0048167 16 16 1,000 2,755E-04 0,01638014 ! learning GO:0007612 16 16 1,000 2,755E-04 0,01586826 ! gene silencing GO:0016458 17 17 1,000 3,12E-04 0,01742384 ! chemotaxis GO:0006935 90 89 2,000 3,203E-04 0,01736465 GO:0042330|taxis, ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 3,507E-04 0,0184656 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 3,507E-04 0,01795266 ! epidermis development GO:0008544 94 94 2,000 3,765E-04 0,01875189 ! glial cell differentiation GO:0010001 19 19 1,000 3,916E-04 0,01899212 ! regulation of cell growth GO:0001558 97 96 2,000 4,006E-04 0,01892971 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 4,347E-04 0,02002975 ! ectoderm development GO:0007398 99 99 2,000 4,386E-04 0,01971477 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 4,801E-04 0,02106556 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 4,801E-04 0,02057566 ! positive regulation of growth GO:0045927 23 23 1,000 5,774E-04 0,02418314 ! gliogenesis GO:0042063 24 24 1,000 6,293E-04 0,02577285 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 7,397E-04 0,02963694 ! response to insulin stimulus GO:0032868 28 26 1,000 7,397E-04 0,02900637 ! learning or memory GO:0007611 28 27 1,000 7,982E-04 0,03064747 ! developmental growth GO:0048589 28 28 1,000 8,588E-04 0,0323032 ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 9,217E-04 0,03397245 ! covalent chromatin modification GO:0016569 29 29 1,000 9,217E-04 0,03330632 ! aging GO:0007568 32 31 1,000 1,054E-03 0,03734757 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 1,194E-03 0,04153486 ! regulation of synaptic transmission GO:0050804 33 33 1,000 1,194E-03 0,0407657 ! muscle cell differentiation GO:0042692 35 34 1,000 1,268E-03 0,04248894 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 1,268E-03 0,04173021 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 1,344E-03 0,0434449 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 1,421E-03 0,04516794 GO:0035113|embryonic appendage morphogenesis, ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 1,421E-03 0,04440238 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 1,501E-03 0,04611707 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 1,501E-03 0,04536105 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 1,501E-03 0,04462942 ! negative regulation of kinase activity GO:0033673 38 38 1,000 1,583E-03 0,04632063 ! regulation of neurological system process GO:0031644 38 38 1,000 1,583E-03 0,04559687 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 1,668E-03 0,04728088 ! limb development GO:0060173 39 39 1,000 1,668E-03 0,0465645 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 1,754E-03 0,04824158 ! negative regulation of transferase activity GO:0051348 40 40 1,000 1,754E-03 0,04753214 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 1,842E-03 0,04920253 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of caspase activity GO:0043281 41 41 1,000 1,842E-03 0,04849964 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 1,933E-03 0,05016357 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 1,933E-03 0,04946686 ! forebrain development GO:0030900 43 42 1,000 1,933E-03 0,04878923 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 1,933E-03 0,04812992 ! mitochondrion organization GO:0007005 44 43 1,000 2,025E-03 0,04976124 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 2,025E-03 0,04910648 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 2,12E-03 0,05073248 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 2,216E-03 0,05236574 ! regulation of peptidase activity GO:0052547 46 46 1,000 2,315E-03 0,05400586 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 2,315E-03 0,05333079 ! positive regulation of ligase activity GO:0051351 47 46 1,000 2,315E-03 0,05267239 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 2,315E-03 0,05203004 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 2,519E-03 0,05592432 ! DNA recombination GO:0006310 48 48 1,000 2,519E-03 0,05525855 ! ossification GO:0001503 50 49 1,000 2,623E-03 0,05688255 GO:0060348|bone development, ! regulation of ligase activity GO:0051340 50 49 1,000 2,623E-03 0,05622113 ! cell fate commitment GO:0045165 52 52 1,000 2,95E-03 0,0624997 ! response to light stimulus GO:0009416 53 52 1,000 2,95E-03 0,06178948 ! in utero embryonic development GO:0001701 55 55 1,000 3,295E-03 0,06824222 ! cellular respiration GO:0045333 62 61 1,000 4,04E-03 0,08272778 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 4,04E-03 0,08181868 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! striated muscle tissue development GO:0014706 69 67 1,000 4,855E-03 0,09726796 ! response to radiation GO:0009314 70 68 1,000 4,998E-03 0,09905141 ! regulation of cell size GO:0008361 68 68 1,000 4,998E-03 0,09799767 ! growth GO:0040007 70 70 1,000 5,29E-03 0,10261846 ! muscle tissue development GO:0060537 72 70 1,000 5,29E-03 0,10154952 ! rRNA transcription GO:0009303 5 5 0,000 7,971E-03 0,15144851 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 7,971E-03 0,14990312 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 7,971E-03 0,14838894 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 7,971E-03 0,14690505 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 7,971E-03 0,14545055 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 7,971E-03 0,14402456 ! reproductive cellular process GO:0048610 5 5 0,000 7,971E-03 0,14262627 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 7,971E-03 0,14125486 ! negative regulation of blood pressure GO:0045776 6 5 0,000 7,971E-03 0,13990957 ! prostate gland development GO:0030850 5 5 0,000 7,971E-03 0,13858967 ! metencephalon development GO:0022037 5 5 0,000 7,971E-03 0,13729444 ! water transport GO:0006833 5 5 0,000 7,971E-03 0,1360232 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 7,971E-03 0,13477528 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 7,971E-03 0,13355005 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 7,971E-03 0,1323469 ! glycerol metabolic process GO:0006071 5 5 0,000 7,971E-03 0,13116523 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 7,971E-03 0,13000447 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 7,971E-03 0,12886408 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 7,971E-03 0,12774352 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 7,971E-03 0,12664229 GO:0010469|regulation of receptor activity, ! filopodium assembly GO:0046847 7 5 0,000 7,971E-03 0,12555987 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 7,971E-03 0,12449581 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 7,971E-03 0,12344962 ! GTP metabolic process GO:0046039 5 5 0,000 7,971E-03 0,12242088 ! establishment of tissue polarity GO:0007164 5 5 0,000 7,971E-03 0,12140914 ! mRNA stabilization GO:0048255 5 5 0,000 7,971E-03 0,12041398 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 7,971E-03 0,119435 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 7,971E-03 0,11847182 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 7,971E-03 0,11752404 ! social behavior GO:0035176 5 5 0,000 7,971E-03 0,11659131 ! macrophage chemotaxis GO:0048246 6 5 0,000 7,971E-03 0,11567327 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 7,971E-03 0,11476957 ! memory GO:0007613 5 5 0,000 7,971E-03 0,11387989 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 7,971E-03 0,11300389 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 7,971E-03 0,11214126 ! membrane hyperpolarization GO:0060081 5 5 0,000 7,971E-03 0,11129171 ! response to lipid GO:0033993 5 5 0,000 7,971E-03 0,11045493 ! erythrocyte maturation GO:0043249 5 5 0,000 7,971E-03 0,10963064 ! hippocampus development GO:0021766 6 5 0,000 7,971E-03 0,10881856 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 7,971E-03 0,10801842 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 7,971E-03 0,10722997 ! middle ear morphogenesis GO:0042474 5 5 0,000 7,971E-03 0,10645294 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 7,971E-03 0,10568709 ! mechanosensory behavior GO:0007638 5 5 0,000 7,971E-03 0,10493218 ! heart looping GO:0001947 5 5 0,000 7,971E-03 0,10418798 ! negative regulation of endocytosis GO:0045806 5 5 0,000 7,971E-03 0,10345426 ! response to interferon-gamma GO:0034341 5 5 0,000 7,971E-03 0,10273081 ! pseudouridine synthesis GO:0001522 5 5 0,000 7,971E-03 0,1020174 ! endocrine pancreas development GO:0031018 5 5 0,000 7,971E-03 0,10131383 ! pH reduction GO:0045851 5 5 0,000 7,971E-03 0,1006199 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 7,971E-03 0,09993541 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 7,971E-03 0,09926017 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 7,971E-03 0,098594 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 7,971E-03 0,0979367 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 7,971E-03 0,09728811 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 7,971E-03 0,09664806 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 7,971E-03 0,09601637 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 7,971E-03 0,09539289 ! adrenal gland development GO:0030325 5 5 0,000 7,971E-03 0,09477745 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 7,971E-03 0,09416991 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 7,971E-03 0,0935701 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 7,971E-03 0,09297788 ! astrocyte differentiation GO:0048708 5 5 0,000 7,971E-03 0,09239312 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 7,971E-03 0,09181566 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 7,971E-03 0,09124537 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 7,971E-03 0,09068213 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 7,971E-03 0,0901258 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 7,971E-03 0,08957625 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 7,971E-03 0,08903337 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 7,971E-03 0,08849702 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 7,971E-03 0,0879671 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 7,971E-03 0,08744348 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 7,971E-03 0,08692607 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 7,971E-03 0,08641474 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 7,971E-03 0,08590939 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 7,971E-03 0,08540991 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 7,971E-03 0,08491622 ! response to ATP GO:0033198 5 5 0,000 7,971E-03 0,08442819 ! regulation of type I interferon production GO:0032479 5 5 0,000 7,971E-03 0,08394574 ! regulation of appetite GO:0032098 5 5 0,000 7,971E-03 0,08346878 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 7,971E-03 0,08299721 ! paraxial mesoderm development GO:0048339 5 5 0,000 7,971E-03 0,08253093 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 7,971E-03 0,08206986 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 7,971E-03 0,08161392 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 7,971E-03 0,08116301 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 7,971E-03 0,08071706 ! receptor clustering GO:0043113 5 5 0,000 7,971E-03 0,08027599 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 7,971E-03 0,0798397 ! fear response GO:0042596 5 5 0,000 7,971E-03 0,07940814 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 7,971E-03 0,07898121 ! lens development in camera-type eye GO:0002088 5 5 0,000 7,971E-03 0,07855885 ! retinol metabolic process GO:0042572 5 5 0,000 7,971E-03 0,07814099 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 7,971E-03 0,07772754 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 7,971E-03 0,07731845 ! positive regulation of exocytosis GO:0045921 6 5 0,000 7,971E-03 0,07691364 ! parturition GO:0007567 5 5 0,000 7,971E-03 0,07651305 ! cellular glucose homeostasis GO:0001678 5 5 0,000 7,971E-03 0,07611661 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 7,971E-03 0,07572425 ! Schwann cell differentiation GO:0014037 5 5 0,000 7,971E-03 0,07533592 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 7,971E-03 0,07495156 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 7,971E-03 0,07457109 ! protein heterooligomerization GO:0051291 5 5 0,000 7,971E-03 0,07419447 ! regulation of gliogenesis GO:0014013 5 5 0,000 7,971E-03 0,07382163 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 7,971E-03 0,07345253 ! response to UV-B GO:0010224 5 5 0,000 7,971E-03 0,07308709 ! oligodendrocyte development GO:0014003 5 5 0,000 7,971E-03 0,07272527 ! hyaluronan metabolic process GO:0030212 5 5 0,000 7,971E-03 0,07236702 ! activated T cell proliferation GO:0050798 5 5 0,000 7,971E-03 0,07201228 ! interaction with symbiont GO:0051702 5 5 0,000 7,971E-03 0,071661 ! cellular extravasation GO:0045123 5 5 0,000 7,971E-03 0,07131313 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 7,971E-03 0,07096862 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 7,971E-03 0,07062743 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 7,971E-03 0,0702895 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 7,971E-03 0,06995479 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 7,971E-03 0,06962325 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 7,971E-03 0,06929484 ! response to amine stimulus GO:0014075 5 5 0,000 7,971E-03 0,06896951 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 7,971E-03 0,06864722 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 7,971E-03 0,06832793 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 7,971E-03 0,0680116 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 7,971E-03 0,06769818 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 7,971E-03 0,06738764 ! neuron recognition GO:0008038 5 5 0,000 7,971E-03 0,06707993 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 7,971E-03 0,06677502 ! decidualization GO:0046697 5 5 0,000 7,971E-03 0,06647287 ! hair follicle maturation GO:0048820 5 5 0,000 7,971E-03 0,06617345 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 7,971E-03 0,06587671 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 7,971E-03 0,06558261 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 7,971E-03 0,06529113 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 7,971E-03 0,06500224 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 7,971E-03 0,06471588 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 7,971E-03 0,06443204 ! postreplication repair GO:0006301 5 5 0,000 7,971E-03 0,06415068 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 7,971E-03 0,06387176 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 7,971E-03 0,06359526 ! histone methylation GO:0016571 5 5 0,000 7,971E-03 0,06332114 ! DNA methylation GO:0006306 5 5 0,000 7,971E-03 0,06304938 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 7,971E-03 0,06277994 ! T cell lineage commitment GO:0002360 5 5 0,000 7,971E-03 0,06251279 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 7,971E-03 0,0622479 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 7,971E-03 0,06198525 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 7,971E-03 0,06172481 ! intracellular cholesterol transport GO:0032367 5 5 0,000 7,971E-03 0,06146655 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 7,971E-03 0,06121044 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 7,971E-03 0,06095645 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 7,971E-03 0,06070457 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 7,971E-03 0,06045475 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 7,971E-03 0,06020699 ! sterol catabolic process GO:0016127 5 5 0,000 7,971E-03 0,05996125 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 7,971E-03 0,0597175 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 7,971E-03 0,05947573 ! detection of biotic stimulus GO:0009595 5 5 0,000 7,971E-03 0,05923591 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 7,971E-03 0,05899801 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 7,971E-03 0,05876202 ! zymogen activation GO:0031638 5 5 0,000 7,971E-03 0,05852791 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 7,971E-03 0,05829566 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 7,971E-03 0,05806524 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 7,971E-03 0,05783664 ! peptidyl-lysine modification GO:0018205 5 5 0,000 7,971E-03 0,05760982 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 7,971E-03 0,05738479 ! peptidyl-histidine modification GO:0018202 5 5 0,000 7,971E-03 0,0571615 ! nucleosome positioning GO:0016584 5 5 0,000 7,971E-03 0,05693994 ! regulation of isotype switching GO:0045191 5 5 0,000 7,971E-03 0,0567201 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 7,971E-03 0,05650194 ! negative regulation of neurological system process GO:0031645 5 5 0,000 7,971E-03 0,05628546 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 7,971E-03 0,05607063 ! glutathione biosynthetic process GO:0006750 5 5 0,000 7,971E-03 0,05585743 ! NADPH regeneration GO:0006740 5 5 0,000 7,971E-03 0,05564585 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 7,971E-03 0,05543587 ! positive regulation of epidermis development GO:0045684 5 5 0,000 7,971E-03 0,05522746 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 7,971E-03 0,05502062 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 7,971E-03 0,05481532 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 7,971E-03 0,05461154 ! sarcomere organization GO:0045214 5 5 0,000 7,971E-03 0,05440928 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 7,971E-03 0,05420851 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 7,971E-03 0,05400921 ! negative regulation of glucose transport GO:0010829 5 5 0,000 7,971E-03 0,05381137 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 7,971E-03 0,05361498 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 7,971E-03 0,05342002 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 7,971E-03 0,05322647 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 7,971E-03 0,05303432 ! spleen development GO:0048536 5 5 0,000 7,971E-03 0,05284354 ! male genitalia development GO:0030539 5 5 0,000 7,971E-03 0,05265414 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 7,971E-03 0,05246609 ! quaternary ammonium group transport GO:0015697 5 5 0,000 7,971E-03 0,05227938 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 7,971E-03 0,05209399 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 7,971E-03 0,05190991 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 7,971E-03 0,05172713 ! removal of superoxide radicals GO:0019430 6 5 0,000 7,971E-03 0,05154563 ! myeloid cell homeostasis GO:0002262 5 5 0,000 7,971E-03 0,0513654 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 7,971E-03 0,05118643 ! ATP catabolic process GO:0006200 5 5 0,000 7,971E-03 0,0510087 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 7,971E-03 0,0508322 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 7,971E-03 0,05065692 ! blastocyst formation GO:0001825 5 5 0,000 7,971E-03 0,05048284 ! regulation of fibrinolysis GO:0051917 5 5 0,000 7,971E-03 0,05030995 ! embryonic gut development GO:0048566 5 5 0,000 7,971E-03 0,05013824 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 7,971E-03 0,04996771 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 7,971E-03 0,04979832 ! activation of innate immune response GO:0002218 5 5 0,000 7,971E-03 0,04963009 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 7,971E-03 0,04946298 ! catecholamine transport GO:0051937 5 5 0,000 7,971E-03 0,049297 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 7,971E-03 0,04913212 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 7,971E-03 0,04896835 ! muscle adaptation GO:0043500 5 5 0,000 7,971E-03 0,04880567 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 7,971E-03 0,04864406 ! embryonic heart tube development GO:0035050 5 5 0,000 7,971E-03 0,04848352 ! cardiac cell differentiation GO:0035051 6 5 0,000 7,971E-03 0,04832403 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 7,971E-03 0,04816559 ! defense response to fungus GO:0050832 5 5 0,000 7,971E-03 0,04800819 ! lysogeny GO:0030069 5 5 0,000 7,971E-03 0,04785181 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 7,971E-03 0,04769645 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 7,971E-03 0,04754209 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 7,971E-03 0,04738873 ! response to nicotine GO:0035094 5 5 0,000 7,971E-03 0,04723635 ! establishment of cell polarity GO:0030010 5 5 0,000 7,971E-03 0,04708495 ! mitochondrion localization GO:0051646 5 5 0,000 7,971E-03 0,04693452 ! nucleus localization GO:0051647 5 5 0,000 7,971E-03 0,04678505 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 7,971E-03 0,04663652 ! heart development GO:0007507 90 87 1,000 8,073E-03 0,04708583 ! male gamete generation GO:0048232 90 88 1,000 8,254E-03 0,04798697 GO:0007283|spermatogenesis, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 8,62E-03 0,04996066 ! brain development GO:0007420 91 90 1,000 8,62E-03 0,04980405 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 8,994E-03 0,05180172 ! tissue morphogenesis GO:0048729 94 93 1,000 9,184E-03 0,05272926 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 9,558E-03 0,05470746 ! axon extension GO:0048675 7 6 0,000 9,558E-03 0,05453808 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 9,558E-03 0,05436975 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 9,558E-03 0,05420246 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 9,558E-03 0,0540362 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 9,558E-03 0,05387095 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 9,558E-03 0,05370671 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 9,558E-03 0,05354347 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 9,558E-03 0,05338121 ! virus-host interaction GO:0019048 6 6 0,000 9,558E-03 0,05321994 ! regulation of S phase GO:0033261 6 6 0,000 9,558E-03 0,05305964 ! myotube differentiation GO:0014902 6 6 0,000 9,558E-03 0,0529003 ! regulation of B cell proliferation GO:0030888 6 6 0,000 9,558E-03 0,05274192 ! bone remodeling GO:0046849 6 6 0,000 9,558E-03 0,05258448 ! N-glycan processing GO:0006491 6 6 0,000 9,558E-03 0,05242798 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 9,558E-03 0,05227241 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 9,558E-03 0,05211775 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 9,558E-03 0,05196401 ! retina development in camera-type eye GO:0060041 6 6 0,000 9,558E-03 0,05181118 ! RNA methylation GO:0001510 6 6 0,000 9,558E-03 0,05165924 ! cartilage condensation GO:0001502 7 6 0,000 9,558E-03 0,05150819 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 9,558E-03 0,05135802 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 9,558E-03 0,05120872 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 9,558E-03 0,05106029 ! artery development GO:0060840 6 6 0,000 9,558E-03 0,05091272 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 9,558E-03 0,050766 ! bile acid metabolic process GO:0008206 6 6 0,000 9,558E-03 0,05062012 ! androgen metabolic process GO:0008209 6 6 0,000 9,558E-03 0,05047507 ! estrogen metabolic process GO:0008210 6 6 0,000 9,558E-03 0,05033086 ! limbic system development GO:0021761 7 6 0,000 9,558E-03 0,05018747 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 9,558E-03 0,05004489 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 9,558E-03 0,04990312 ! positive regulation of heart contraction GO:0045823 6 6 0,000 9,558E-03 0,04976215 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 9,558E-03 0,04962197 ! pathogenesis GO:0009405 6 6 0,000 9,558E-03 0,04948259 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 9,558E-03 0,04934398 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 9,558E-03 0,04920615 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 9,558E-03 0,04906908 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 9,558E-03 0,04893278 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 9,558E-03 0,04879723 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 9,558E-03 0,04866243 ! arginine metabolic process GO:0006525 6 6 0,000 9,558E-03 0,04852838 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 9,558E-03 0,04839506 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 9,558E-03 0,04826247 ! glutamate catabolic process GO:0006538 7 6 0,000 9,558E-03 0,0481306 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 9,558E-03 0,04799946 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 9,558E-03 0,04786902 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 9,558E-03 0,0477393 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 9,558E-03 0,04761027 ! ER overload response GO:0006983 6 6 0,000 9,558E-03 0,04748194 ! V(D)J recombination GO:0033151 6 6 0,000 9,558E-03 0,0473543 ! focal adhesion formation GO:0048041 7 6 0,000 9,558E-03 0,04722735 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 9,558E-03 0,04710107 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 9,558E-03 0,04697547 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 9,558E-03 0,04685053 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 9,558E-03 0,04672626 ! regulation of heart rate GO:0002027 6 6 0,000 9,558E-03 0,04660265 ! lipid digestion GO:0044241 6 6 0,000 9,558E-03 0,04647968 ! asymmetric protein localization GO:0008105 6 6 0,000 9,558E-03 0,04635737 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 9,558E-03 0,0462357 ! phagocytosis, engulfment GO:0006911 6 6 0,000 9,558E-03 0,04611466 ! Rac protein signal transduction GO:0016601 6 6 0,000 9,558E-03 0,04599426 ! regulation of vascular permeability GO:0043114 6 6 0,000 9,558E-03 0,04587448 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 9,558E-03 0,04575533 ! ruffle organization GO:0031529 6 6 0,000 9,558E-03 0,04563679 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 9,558E-03 0,04551886 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 9,558E-03 0,04540155 ! retinoic acid metabolic process GO:0042573 6 6 0,000 9,558E-03 0,04528483 ! neutral amino acid transport GO:0015804 6 6 0,000 9,558E-03 0,04516872 ! L-amino acid transport GO:0015807 6 6 0,000 9,558E-03 0,0450532 ! bone mineralization GO:0030282 6 6 0,000 9,558E-03 0,04493827 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 9,558E-03 0,04482392 ! negative regulation of ossification GO:0030279 6 6 0,000 9,558E-03 0,04471015 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 9,558E-03 0,04459696 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 9,558E-03 0,04448434 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 9,558E-03 0,04437229 ! purine base biosynthetic process GO:0009113 6 6 0,000 9,558E-03 0,04426081 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 9,558E-03 0,04414988 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 9,558E-03 0,0440395 ! regulation of phagocytosis GO:0050764 6 6 0,000 9,558E-03 0,04392968 ! regulation of organ growth GO:0046620 6 6 0,000 9,558E-03 0,0438204 ! regulation of circadian rhythm GO:0042752 6 6 0,000 9,558E-03 0,04371166 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 9,558E-03 0,04360347 ! response to dsRNA GO:0043331 6 6 0,000 9,558E-03 0,0434958 ! DNA unwinding during replication GO:0006268 6 6 0,000 9,558E-03 0,04338867 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 9,558E-03 0,04328207 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 9,558E-03 0,04317598 ! genitalia development GO:0048806 6 6 0,000 9,558E-03 0,04307042 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 9,558E-03 0,04296537 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 9,558E-03 0,04286083 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 9,558E-03 0,0427568 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 9,558E-03 0,04265327 ! multicellular organismal aging GO:0010259 6 6 0,000 9,558E-03 0,04255024 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 9,558E-03 0,04244771 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 9,558E-03 0,04234567 ! erythrocyte development GO:0048821 6 6 0,000 9,558E-03 0,04224413 ! renal water homeostasis GO:0003091 6 6 0,000 9,558E-03 0,04214306 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 9,558E-03 0,04204248 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 9,558E-03 0,04194238 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 9,558E-03 0,04184276 ! ribosome assembly GO:0042255 6 6 0,000 9,558E-03 0,0417436 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 9,558E-03 0,04164492 ! diencephalon development GO:0021536 6 6 0,000 9,558E-03 0,0415467 ! fucose catabolic process GO:0019317 6 6 0,000 9,558E-03 0,04144894 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 9,558E-03 0,04135164 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 9,558E-03 0,0412548 ! regulation of lipid transport GO:0032368 6 6 0,000 9,558E-03 0,04115841 ! regulation of cell division GO:0051302 6 6 0,000 9,558E-03 0,04106247 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 9,558E-03 0,04096698 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 9,558E-03 0,04087193 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 9,558E-03 0,04077732 ! salivary gland morphogenesis GO:0007435 6 6 0,000 9,558E-03 0,04068314 ! neuroblast proliferation GO:0007405 6 6 0,000 9,558E-03 0,0405894 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 9,558E-03 0,04049609 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 9,558E-03 0,04040321 ! regulation of glucose transport GO:0010827 6 6 0,000 9,558E-03 0,04031076 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 9,558E-03 0,04021872 ! methionine biosynthetic process GO:0009086 6 6 0,000 9,558E-03 0,04012711 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 9,558E-03 0,04003591 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 9,558E-03 0,03994513 ! thymus development GO:0048538 6 6 0,000 9,558E-03 0,03985475 ! lymph node development GO:0048535 6 6 0,000 9,558E-03 0,03976479 ! organic cation transport GO:0015695 6 6 0,000 9,558E-03 0,03967523 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 9,558E-03 0,03958607 ! regulation of RNA splicing GO:0043484 6 6 0,000 9,558E-03 0,03949731 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 9,558E-03 0,03940895 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 9,558E-03 0,03932098 ! sperm-egg recognition GO:0035036 7 6 0,000 9,558E-03 0,03923341 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 9,558E-03 0,03914622 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 9,558E-03 0,03905942 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 9,558E-03 0,03897301 ! alditol metabolic process GO:0019400 6 6 0,000 9,558E-03 0,03888698 ! regulation of amino acid transport GO:0051955 6 6 0,000 9,558E-03 0,03880132 ! maternal placenta development GO:0001893 6 6 0,000 9,558E-03 0,03871605 ! regulation of embryonic development GO:0045995 6 6 0,000 9,558E-03 0,03863114 ! negative regulation of immune effector process GO:0002698 6 6 0,000 9,558E-03 0,03854661 ! localization within membrane GO:0051668 6 6 0,000 9,558E-03 0,03846245 ! endocytosis GO:0006897 99 98 1,000 0,0101593 0,04079213 GO:0010324|membrane invagination, ! regulation of system process GO:0044057 98 98 1,000 0,0101593 0,04070346 ! anti-apoptosis GO:0006916 100 99 1,000 0,01035973 0,04141644 ! response to hormone stimulus GO:0009725 102 100 1,000 0,01056193 0,04213342 ! muscle organ development GO:0007517 102 100 1,000 0,01056193 0,04204242 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,01056193 0,04195181 ! respiratory burst GO:0045730 7 7 0,000 0,01114316 0,04416525 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,01114316 0,04407047 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,01114316 0,0439761 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,01114316 0,04388214 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,01114316 0,04378857 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,01114316 0,0436954 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,01114316 0,04360263 ! regulation of chemokine production GO:0032642 7 7 0,000 0,01114316 0,04351025 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,01114316 0,04341827 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,01114316 0,04332667 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,01114316 0,04323545 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,01114316 0,04314462 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,01114316 0,04305417 ! gene silencing by RNA GO:0031047 7 7 0,000 0,01114316 0,0429641 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,01114316 0,04287441 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,01114316 0,04278508 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,01114316 0,04269613 ! axis specification GO:0009798 7 7 0,000 0,01114316 0,04260755 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,01114316 0,04251934 ! startle response GO:0001964 7 7 0,000 0,01114316 0,04243149 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,01114316 0,042344 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,01114316 0,04225687 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,01114316 0,0421701 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,01114316 0,04208369 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,01114316 0,04199763 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,01114316 0,04191192 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,01114316 0,04182656 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,01114316 0,04174155 ! digestive system development GO:0055123 7 7 0,000 0,01114316 0,04165688 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,01114316 0,04157255 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,01114316 0,04148857 ! protein targeting to ER GO:0045047 8 7 0,000 0,01114316 0,04140492 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,01114316 0,04132161 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,01114316 0,04123863 ! endoderm development GO:0007492 7 7 0,000 0,01114316 0,04115599 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,01114316 0,04107368 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,01114316 0,0409917 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,01114316 0,04091004 ! response to hexose stimulus GO:0009746 7 7 0,000 0,01114316 0,04082871 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,01114316 0,0407477 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,01114316 0,04066701 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,01114316 0,04058664 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,01114316 0,04050659 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,01114316 0,04042685 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,01114316 0,04034743 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,01114316 0,04026831 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,01114316 0,04018951 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,01114316 0,04011102 ! response to X-ray GO:0010165 7 7 0,000 0,01114316 0,04003283 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,01114316 0,03995494 ! UV protection GO:0009650 7 7 0,000 0,01114316 0,03987736 ! DNA integration GO:0015074 7 7 0,000 0,01114316 0,03980008 ! myofibril assembly GO:0030239 7 7 0,000 0,01114316 0,0397231 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,01114316 0,03964641 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,01114316 0,03957002 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,01114316 0,03949392 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,01114316 0,03941812 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,01114316 0,03934261 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,01114316 0,03926738 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,01114316 0,03919244 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,01114316 0,03911779 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,01114316 0,03904342 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,01114316 0,03896934 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,01114316 0,03889553 ! axon cargo transport GO:0008088 7 7 0,000 0,01114316 0,038822 ! eating behavior GO:0042755 7 7 0,000 0,01114316 0,03874875 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,01114316 0,03867578 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,01114316 0,03860308 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,01114316 0,03853066 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,01114316 0,0384585 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,01114316 0,03838662 ! cranial nerve development GO:0021545 7 7 0,000 0,01114316 0,038315 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,01114316 0,03824365 ! induction of an organ GO:0001759 7 7 0,000 0,01114316 0,03817257 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,01114316 0,03810174 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,01114316 0,03803119 ! autonomic nervous system development GO:0048483 7 7 0,000 0,01114316 0,03796089 ! intracellular lipid transport GO:0032365 7 7 0,000 0,01114316 0,03789085 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,01114316 0,03782107 ! platelet activation GO:0030168 8 7 0,000 0,01114316 0,03775154 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,01114316 0,03768228 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,01114316 0,03761326 ! natural killer cell activation GO:0030101 7 7 0,000 0,01114316 0,0375445 ! response to gamma radiation GO:0010332 8 7 0,000 0,01114316 0,03747599 ! NADP metabolic process GO:0006739 7 7 0,000 0,01114316 0,03740772 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,01114316 0,03733971 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,01114316 0,03727194 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,01114316 0,03720442 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,01114316 0,03713714 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,01114316 0,03707011 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,01114316 0,03700332 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,01114316 0,03693676 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,01114316 0,03687045 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,01114316 0,03680437 ! cell-cell recognition GO:0009988 8 7 0,000 0,01114316 0,03673853 ! hormone catabolic process GO:0042447 7 7 0,000 0,01114316 0,03667293 ! dopamine metabolic process GO:0042417 7 7 0,000 0,01114316 0,03660756 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,01114316 0,03654242 ! oxygen transport GO:0015671 7 7 0,000 0,01114316 0,03647751 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,01114316 0,03641284 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,01114316 0,03634839 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,01114316 0,03628417 ! regulation of axon extension GO:0030516 7 7 0,000 0,01114316 0,03622018 ! cell killing GO:0001906 7 7 0,000 0,01114316 0,03615641 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,01114316 0,03609286 ! adult feeding behavior GO:0008343 7 7 0,000 0,01114316 0,03602954 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,01114316 0,03596645 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,01114316 0,03590357 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,01114316 0,03584091 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,01114316 0,03577847 ! response to cold GO:0009409 7 7 0,000 0,01114316 0,03571624 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,01272579 0,04071811 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,01272579 0,04064754 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,01272579 0,04057721 ! positive regulation of translation GO:0045727 8 8 0,000 0,01272579 0,04050713 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,01272579 0,04043729 ! superoxide anion generation GO:0042554 8 8 0,000 0,01272579 0,04036769 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,01272579 0,04029833 ! cGMP metabolic process GO:0046068 8 8 0,000 0,01272579 0,04022921 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,01272579 0,04016032 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,01272579 0,04009167 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,01272579 0,04002326 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,01272579 0,03995508 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,01272579 0,03988713 ! zinc ion transport GO:0006829 8 8 0,000 0,01272579 0,03981941 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,01272579 0,03975191 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,01272579 0,03968465 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,01272579 0,03961762 ! lipid localization GO:0010876 8 8 0,000 0,01272579 0,03955081 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,01272579 0,03948423 ! response to cAMP GO:0051591 8 8 0,000 0,01272579 0,03941787 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,01272579 0,03935173 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,01272579 0,03928581 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,01272579 0,03922012 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,01272579 0,03915464 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,01272579 0,03908938 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,01272579 0,03902434 ! sensory perception of taste GO:0050909 8 8 0,000 0,01272579 0,03895952 ! organelle fusion GO:0048284 8 8 0,000 0,01272579 0,03889491 ! pancreas development GO:0031016 8 8 0,000 0,01272579 0,03883051 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,01272579 0,03876633 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,01272579 0,03870236 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,01272579 0,0386386 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,01272579 0,03857505 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,01272579 0,03851171 ! sperm motility GO:0030317 8 8 0,000 0,01272579 0,03844857 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,01272579 0,03838565 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,01272579 0,03832292 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,01272579 0,03826041 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,01272579 0,03819809 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,01272579 0,03813598 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01272579 0,03807407 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,01272579 0,03801237 ! Golgi organization GO:0007030 8 8 0,000 0,01272579 0,03795086 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,01272579 0,03788955 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,01272579 0,03782844 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,01272579 0,03776752 ! fructose metabolic process GO:0006000 8 8 0,000 0,01272579 0,0377068 ! mannose metabolic process GO:0006013 9 8 0,000 0,01272579 0,03764628 ! NAD metabolic process GO:0019674 8 8 0,000 0,01272579 0,03758595 ! sex determination GO:0007530 8 8 0,000 0,01272579 0,03752581 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,01272579 0,03746586 ! plasma membrane fusion GO:0045026 8 8 0,000 0,01272579 0,03740611 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,01272579 0,03734654 ! response to fungus GO:0009620 8 8 0,000 0,01272579 0,03728717 ! stem cell differentiation GO:0048863 8 8 0,000 0,01272579 0,03722798 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,01272579 0,03716899 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,01272579 0,03711017 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,01272579 0,03705155 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,01272579 0,03699311 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01272579 0,03693485 ! regulation of vasodilation GO:0042312 8 8 0,000 0,01272579 0,03687678 ! vasoconstriction GO:0042310 8 8 0,000 0,01272579 0,03681888 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,01272579 0,03676118 ! muscle cell development GO:0055001 8 8 0,000 0,01272579 0,03670365 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,01272579 0,0366463 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,01272579 0,03658913 ! sensory perception of pain GO:0019233 8 8 0,000 0,01272579 0,03653213 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,01272579 0,03647532 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,01272579 0,03641868 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,01272579 0,03636222 ! tissue regeneration GO:0042246 8 8 0,000 0,01272579 0,03630593 ! salivary gland development GO:0007431 8 8 0,000 0,01272579 0,03624981 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,01272579 0,03619387 ! T cell homeostasis GO:0043029 8 8 0,000 0,01272579 0,0361381 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,01272579 0,03608251 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,01272579 0,03602708 ! water homeostasis GO:0030104 8 8 0,000 0,01272579 0,03597182 ! cofactor transport GO:0051181 8 8 0,000 0,01272579 0,03591674 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,01272579 0,03586182 ! acid secretion GO:0046717 8 8 0,000 0,01272579 0,03580707 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,01272579 0,03575248 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,01272579 0,03569807 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,01272579 0,03564381 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,01272579 0,03558973 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,01272579 0,0355358 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,01272579 0,03548204 ! regulation of RNA stability GO:0043487 8 8 0,000 0,01272579 0,03542844 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,01272579 0,03537501 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,01272579 0,03532173 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,01272579 0,03526862 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,01272579 0,03521566 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,01272579 0,03516286 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,01272579 0,03511022 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,01272579 0,03505774 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,01272579 0,03500542 ! developmental induction GO:0031128 8 8 0,000 0,01272579 0,03495325 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,01272579 0,03490123 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,01272579 0,03484938 ! actin filament polymerization GO:0030041 9 8 0,000 0,01272579 0,03479767 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,01272579 0,03474612 ! peptide hormone processing GO:0016486 8 8 0,000 0,01272579 0,03469472 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,01272579 0,03464347 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,01272579 0,03459237 ! lactation GO:0007595 10 9 0,000 0,01430612 0,03883089 ! embryonic pattern specification GO:0009880 10 9 0,000 0,01430612 0,03877379 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,01430612 0,03871685 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,01430612 0,03866008 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,01430612 0,03860348 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,01430612 0,03854704 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,01430612 0,03849077 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,01430612 0,03843466 ! viral genome replication GO:0019079 9 9 0,000 0,01430612 0,03837871 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,01430612 0,03832293 ! copper ion transport GO:0006825 9 9 0,000 0,01430612 0,03826731 ! lipid phosphorylation GO:0046834 9 9 0,000 0,01430612 0,03821185 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,01430612 0,03815655 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,01430612 0,03810141 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,01430612 0,03804643 ! RNA polyadenylation GO:0043631 9 9 0,000 0,01430612 0,03799161 GO:0006378|mRNA polyadenylation, ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,01430612 0,03793694 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,01430612 0,03788244 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,01430612 0,03782808 ! phospholipid efflux GO:0033700 9 9 0,000 0,01430612 0,03777389 ! response to alkaloid GO:0043279 10 9 0,000 0,01430612 0,03771985 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,01430612 0,03766596 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,01430612 0,03761223 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,01430612 0,03755865 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,01430612 0,03750523 ! response to ethanol GO:0045471 9 9 0,000 0,01430612 0,03745195 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,01430612 0,03739883 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,01430612 0,03734586 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,01430612 0,03729303 ! methionine metabolic process GO:0006555 9 9 0,000 0,01430612 0,03724036 ! glutamine metabolic process GO:0006541 9 9 0,000 0,01430612 0,03718783 ! cerebral cortex development GO:0021987 9 9 0,000 0,01430612 0,03713546 ! response to osmotic stress GO:0006970 9 9 0,000 0,01430612 0,03708323 ! pigmentation during development GO:0048066 9 9 0,000 0,01430612 0,03703114 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,01430612 0,03697921 ! central nervous system neuron development GO:0021954 10 9 0,000 0,01430612 0,03692742 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,01430612 0,03687577 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,01430612 0,03682427 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,01430612 0,03677291 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,01430612 0,03672169 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,01430612 0,03667062 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,01430612 0,03661969 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,01430612 0,0365689 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,01430612 0,03651825 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,01430612 0,03646774 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,01430612 0,03641737 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,01430612 0,03636714 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,01430612 0,03631705 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,01430612 0,03626709 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,01430612 0,03621727 ! DNA replication initiation GO:0006270 9 9 0,000 0,01430612 0,03616759 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,01430612 0,03611805 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,01430612 0,03606864 ! regulation of cellular pH GO:0030641 9 9 0,000 0,01430612 0,03601936 ! histone acetylation GO:0016573 9 9 0,000 0,01430612 0,03597022 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,01430612 0,03592122 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,01430612 0,03587235 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,01430612 0,03582361 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,01430612 0,035775 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,01430612 0,03572652 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,01430612 0,03567818 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,01430612 0,03562997 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,01430612 0,03558188 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,01430612 0,03553393 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,01430612 0,0354861 ! collagen catabolic process GO:0030574 9 9 0,000 0,01430612 0,03543841 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,01430612 0,03539084 ! purine base metabolic process GO:0006144 9 9 0,000 0,01430612 0,0353434 ! gas transport GO:0015669 9 9 0,000 0,01430612 0,03529608 ! cholesterol efflux GO:0033344 9 9 0,000 0,01430612 0,0352489 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,01430612 0,03520184 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,01430612 0,0351549 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,01430612 0,03510809 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,01430612 0,0350614 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,01430612 0,03501484 ! defense response to virus GO:0051607 9 9 0,000 0,01430612 0,0349684 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,01430612 0,03492209 ! actin filament-based movement GO:0030048 9 9 0,000 0,01430612 0,03487589 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,01430612 0,03482982 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01588415 0,03862069 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,01588415 0,0385698 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01588415 0,03851905 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01588415 0,03846844 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,01588415 0,03841795 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01588415 0,0383676 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01588415 0,03831738 ! neuron maturation GO:0042551 10 10 0,000 0,01588415 0,0382673 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01588415 0,03821734 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01588415 0,03816751 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01588415 0,03811781 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01588415 0,03806825 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01588415 0,03801881 ! hormone secretion GO:0046879 10 10 0,000 0,01588415 0,0379695 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01588415 0,03792031 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01588415 0,03787126 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,01588415 0,03782233 ! inositol metabolic process GO:0006020 10 10 0,000 0,01588415 0,03777352 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01588415 0,03772485 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01588415 0,03767629 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01588415 0,03762787 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01588415 0,03757956 ! glial cell development GO:0021782 10 10 0,000 0,01588415 0,03753139 ! phototransduction GO:0007602 11 10 0,000 0,01588415 0,03748333 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01588415 0,0374354 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01588415 0,03738759 ! fat cell differentiation GO:0045444 10 10 0,000 0,01588415 0,0373399 ! myoblast differentiation GO:0045445 10 10 0,000 0,01588415 0,03729233 ! centrosome cycle GO:0007098 10 10 0,000 0,01588415 0,03724489 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01588415 0,03719756 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01588415 0,03715036 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01588415 0,03710327 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01588415 0,03705631 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01588415 0,03700946 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01588415 0,03696273 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01588415 0,03691612 ! plasma membrane organization GO:0007009 10 10 0,000 0,01588415 0,03686962 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01588415 0,03682325 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01588415 0,03677699 ! lysosomal transport GO:0007041 10 10 0,000 0,01588415 0,03673084 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01588415 0,03668481 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01588415 0,0366389 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,01588415 0,0365931 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,01588415 0,03654742 ! exocrine system development GO:0035272 10 10 0,000 0,01588415 0,03650185 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01588415 0,03645639 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01588415 0,03641105 ! embryo implantation GO:0007566 11 10 0,000 0,01588415 0,03636581 ! regulation of protein binding GO:0043393 11 10 0,000 0,01588415 0,0363207 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01588415 0,03627569 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01588415 0,03623079 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,01588415 0,03618601 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01588415 0,03614133 ! protein export from nucleus GO:0006611 10 10 0,000 0,01588415 0,03609677 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01588415 0,03605232 ! cytolysis GO:0019835 10 10 0,000 0,01588415 0,03600797 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01588415 0,03596374 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01588415 0,03591961 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01588415 0,03587559 ! histone deacetylation GO:0016575 10 10 0,000 0,01588415 0,03583168 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01588415 0,03578787 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01588415 0,03574418 ! gland morphogenesis GO:0022612 10 10 0,000 0,01588415 0,03570059 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01588415 0,0356571 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01588415 0,03561372 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01588415 0,03557045 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01588415 0,03552728 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,01588415 0,03548422 ! regulation of epidermis development GO:0045682 10 10 0,000 0,01588415 0,03544126 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01588415 0,03539841 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,01588415 0,03535565 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01588415 0,035313 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01588415 0,03527046 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01588415 0,03522802 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01588415 0,03518567 ! nerve development GO:0021675 10 10 0,000 0,01588415 0,03514343 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,01588415 0,0351013 ! gut development GO:0048565 10 10 0,000 0,01588415 0,03505926 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01588415 0,03501732 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,01588415 0,03497549 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01588415 0,03493375 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01588415 0,03489211 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01588415 0,03485057 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01588415 0,03480913 ! protein stabilization GO:0050821 10 10 0,000 0,01588415 0,03476779 ! protein secretion GO:0009306 11 11 0,000 0,01745988 0,03817148 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01745988 0,03812625 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01745988 0,03808113 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01745988 0,03803612 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01745988 0,03799121 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01745988 0,03794641 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,01745988 0,03790171 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01745988 0,03785712 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01745988 0,03781264 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,01745988 0,03776826 ! signal complex assembly GO:0007172 11 11 0,000 0,01745988 0,03772398 ! microtubule-based transport GO:0010970 11 11 0,000 0,01745988 0,03767981 ! endothelial cell migration GO:0043542 11 11 0,000 0,01745988 0,03763574 ! peroxisomal transport GO:0043574 11 11 0,000 0,01745988 0,03759177 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01745988 0,0375479 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,01745988 0,03750414 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01745988 0,03746048 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01745988 0,03741692 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01745988 0,03737347 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01745988 0,03733011 ! T cell proliferation GO:0042098 11 11 0,000 0,01745988 0,03728685 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01745988 0,0372437 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01745988 0,03720064 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,01745988 0,03715768 ! spinal cord development GO:0021510 11 11 0,000 0,01745988 0,03711483 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01745988 0,03707207 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01745988 0,03702941 ! cellular response to starvation GO:0009267 11 11 0,000 0,01745988 0,03698684 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01745988 0,03694438 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,01745988 0,03690201 ! digestive system process GO:0022600 11 11 0,000 0,01745988 0,03685974 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01745988 0,03681757 ! fucose metabolic process GO:0006004 11 11 0,000 0,01745988 0,03677549 ! membrane budding GO:0006900 11 11 0,000 0,01745988 0,03673351 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,01745988 0,03669162 ! monoamine transport GO:0015844 11 11 0,000 0,01745988 0,03664983 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01745988 0,03660814 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01745988 0,03656654 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01745988 0,03652503 ! body fluid secretion GO:0007589 11 11 0,000 0,01745988 0,03648362 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01745988 0,0364423 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,01745988 0,03640108 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01745988 0,03635995 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01745988 0,03631891 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01745988 0,03627796 ! membrane depolarization GO:0051899 11 11 0,000 0,01745988 0,03623711 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01745988 0,03619635 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01745988 0,03615568 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,01745988 0,0361151 ! oogenesis GO:0048477 11 11 0,000 0,01745988 0,03607461 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01745988 0,03603421 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01745988 0,03599391 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,01745988 0,03595369 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,01745988 0,03591356 ! muscle maintenance GO:0046716 12 11 0,000 0,01745988 0,03587353 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01745988 0,03583358 ! steroid catabolic process GO:0006706 11 11 0,000 0,01745988 0,03579372 ! endocrine process GO:0050886 11 11 0,000 0,01745988 0,03575395 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01745988 0,03571427 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01745988 0,03567467 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01745988 0,03563516 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,01745988 0,03559575 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01745988 0,03555641 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,01903331 0,03871788 ! translational initiation GO:0006413 12 12 0,000 0,01903331 0,03867519 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,01903331 0,0386326 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,01903331 0,0385901 ! initiation of viral infection GO:0019059 12 12 0,000 0,01903331 0,03854769 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,01903331 0,03850538 ! iron ion transport GO:0006826 13 12 0,000 0,01903331 0,03846316 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,01903331 0,03842103 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,01903331 0,03837899 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,01903331 0,03833705 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,01903331 0,0382952 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,01903331 0,03825343 ! collagen metabolic process GO:0032963 12 12 0,000 0,01903331 0,03821176 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,01903331 0,03817018 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,01903331 0,03812869 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,01903331 0,0380873 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,01903331 0,03804599 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,01903331 0,03800477 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,01903331 0,03796364 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,01903331 0,03792259 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,01903331 0,03788164 ! retinoid metabolic process GO:0001523 12 12 0,000 0,01903331 0,03784078 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,01903331 0,0378 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,01903331 0,03775931 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,01903331 0,03771871 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,01903331 0,03767819 ! acute-phase response GO:0006953 12 12 0,000 0,01903331 0,03763777 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01903331 0,03759743 ! vacuolar transport GO:0007034 12 12 0,000 0,01903331 0,03755717 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,01903331 0,037517 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,01903331 0,03747692 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,01903331 0,03743693 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,01903331 0,03739701 GO:0051693|actin filament capping, ! male gonad development GO:0008584 12 12 0,000 0,01903331 0,03735719 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,01903331 0,03731745 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,01903331 0,03727779 ! renal system process GO:0003014 12 12 0,000 0,01903331 0,03723822 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,01903331 0,03719873 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,01903331 0,03715932 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,01903331 0,03712 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,01903331 0,03708076 ! pallium development GO:0021543 13 12 0,000 0,01903331 0,0370416 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,01903331 0,03700253 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,01903331 0,03696354 ! somitogenesis GO:0001756 13 12 0,000 0,01903331 0,03692463 ! G1 phase GO:0051318 13 12 0,000 0,01903331 0,0368858 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,01903331 0,03684706 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,01903331 0,03680839 ! detection of light stimulus GO:0009583 13 12 0,000 0,01903331 0,03676981 ! synaptogenesis GO:0007416 12 12 0,000 0,01903331 0,03673131 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,01903331 0,03669289 ! hormone transport GO:0009914 12 12 0,000 0,01903331 0,03665454 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,01903331 0,03661628 ! heme biosynthetic process GO:0006783 12 12 0,000 0,01903331 0,0365781 ! spermatid differentiation GO:0048515 13 12 0,000 0,01903331 0,03654 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,01903331 0,03650198 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,01903331 0,03646403 ! neural tube closure GO:0001843 13 12 0,000 0,01903331 0,03642617 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,01903331 0,03638838 ! negative regulation of translation GO:0017148 12 12 0,000 0,01903331 0,03635067 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,01903331 0,03631304 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,01903331 0,03627549 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,02060446 0,03922936 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,02060446 0,03918888 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,02060446 0,03914848 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,02060446 0,03910816 ! phenol metabolic process GO:0018958 13 13 0,000 0,02060446 0,03906792 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,02060446 0,03902777 ! gluconeogenesis GO:0006094 13 13 0,000 0,02060446 0,0389877 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,02060446 0,03894771 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,02060446 0,03890781 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,02060446 0,03886799 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,02060446 0,03882824 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,02060446 0,03878858 ! regeneration GO:0031099 13 13 0,000 0,02060446 0,038749 ! keratinization GO:0031424 13 13 0,000 0,02060446 0,0387095 ! post-embryonic development GO:0009791 14 13 0,000 0,02060446 0,03867008 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,02060446 0,03863074 ! patterning of blood vessels GO:0001569 13 13 0,000 0,02060446 0,03859149 ! vasculogenesis GO:0001570 13 13 0,000 0,02060446 0,03855231 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,02060446 0,03851321 ! regulation of innate immune response GO:0045088 13 13 0,000 0,02060446 0,03847419 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,02060446 0,03843524 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,02060446 0,03839638 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,02060446 0,0383576 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,02060446 0,03831889 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,02060446 0,03828026 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,02060446 0,03824171 ! autophagy GO:0006914 13 13 0,000 0,02060446 0,03820324 ! receptor metabolic process GO:0043112 14 13 0,000 0,02060446 0,03816485 ! actin filament bundle formation GO:0051017 13 13 0,000 0,02060446 0,03812653 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,02060446 0,03808829 ! ureteric bud development GO:0001657 13 13 0,000 0,02060446 0,03805012 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,02060446 0,03801203 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,02060446 0,03797402 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,02060446 0,03793609 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,02060446 0,03789823 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,02060446 0,03786044 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,02060446 0,03782273 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,02060446 0,0377851 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,02060446 0,03774754 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,02060446 0,03771005 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,02060446 0,03767264 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,02060446 0,0376353 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,02060446 0,03759804 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,02060446 0,03756085 ! vasodilation GO:0042311 14 13 0,000 0,02060446 0,03752374 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,02060446 0,03748669 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,02060446 0,03744973 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,02060446 0,03741283 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,02060446 0,03737601 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,02060446 0,03733925 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,02060446 0,03730258 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,02060446 0,03726597 ! immunoglobulin production GO:0002377 13 13 0,000 0,02060446 0,03722943 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,02060446 0,03719297 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,02060446 0,03715658 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,02060446 0,03712026 ! cell-cell junction organization GO:0045216 13 13 0,000 0,02060446 0,03708401 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,02060446 0,03704783 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,02060446 0,03701172 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,02060446 0,03697568 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,02060446 0,03693971 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,02060446 0,03690381 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,02060446 0,03686798 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,02060446 0,03683222 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,02060446 0,03679653 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,02060446 0,03676091 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,02060446 0,03672536 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,02060446 0,03668988 ! telomere organization GO:0032200 13 13 0,000 0,02060446 0,03665446 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,02060446 0,03661911 ! regulation of amine transport GO:0051952 13 13 0,000 0,02060446 0,03658384 ! tissue homeostasis GO:0001894 13 13 0,000 0,02060446 0,03654863 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,02060446 0,03651348 ! protein tetramerization GO:0051262 13 13 0,000 0,02060446 0,03647841 ! neuron fate commitment GO:0048663 14 14 0,000 0,02217332 0,03921826 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,02217332 0,03918066 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,02217332 0,03914313 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,02217332 0,03910567 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,02217332 0,03906829 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,02217332 0,03903097 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,02217332 0,03899373 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,02217332 0,03895656 ! protein amino acid acylation GO:0043543 14 14 0,000 0,02217332 0,03891946 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,02217332 0,03888242 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,02217332 0,03884546 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,02217332 0,03880857 ! vesicle docking GO:0048278 14 14 0,000 0,02217332 0,03877175 ! superoxide metabolic process GO:0006801 15 14 0,000 0,02217332 0,038735 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,02217332 0,03869832 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,02217332 0,03866171 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,02217332 0,03862517 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,02217332 0,03858869 ! hair cycle GO:0042633 14 14 0,000 0,02217332 0,03855229 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,02217332 0,03851595 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,02217332 0,03847969 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,02217332 0,03844349 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,02217332 0,03840736 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,02217332 0,03837129 ! lysosome organization GO:0007040 14 14 0,000 0,02217332 0,0383353 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,02217332 0,03829937 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,02217332 0,03826351 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,02217332 0,03822772 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,02217332 0,03819199 ! primary neural tube formation GO:0014020 15 14 0,000 0,02217332 0,03815633 ! peptide cross-linking GO:0018149 14 14 0,000 0,02217332 0,03812074 ! regulation of behavior GO:0050795 14 14 0,000 0,02217332 0,03808521 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,02217332 0,03804975 ! base-excision repair GO:0006284 14 14 0,000 0,02217332 0,03801435 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,02217332 0,03797902 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,02217332 0,03794376 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,02217332 0,03790856 ! formation of primary germ layer GO:0001704 14 14 0,000 0,02217332 0,03787343 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,02217332 0,03783836 ! collagen fibril organization GO:0030199 14 14 0,000 0,02217332 0,03780336 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,02217332 0,03776842 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,02217332 0,03773354 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,02217332 0,03769873 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,02217332 0,03766399 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,02217332 0,03762931 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,02217332 0,03759469 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,02217332 0,03756014 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,02217332 0,03752565 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,02217332 0,03749122 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,02373989 0,04010323 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,02373989 0,0400665 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,02373989 0,04002985 ! positive regulation of ossification GO:0045778 15 15 0,000 0,02373989 0,03999326 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,02373989 0,03995673 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,02373989 0,03992028 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,02373989 0,03988389 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,02373989 0,03984756 ! response to vitamin GO:0033273 15 15 0,000 0,02373989 0,0398113 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,02373989 0,03977511 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,02373989 0,03973899 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,02373989 0,03970292 ! ovarian follicle development GO:0001541 15 15 0,000 0,02373989 0,03966693 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,02373989 0,039631 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,02373989 0,03959513 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,02373989 0,03955933 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,02373989 0,0395236 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,02373989 0,03948793 ! heme metabolic process GO:0042168 15 15 0,000 0,02373989 0,03945232 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,02373989 0,03941678 ! chromosome condensation GO:0030261 15 15 0,000 0,02373989 0,0393813 ! response to starvation GO:0042594 15 15 0,000 0,02373989 0,03934588 ! response to ionizing radiation GO:0010212 16 15 0,000 0,02373989 0,03931053 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,02373989 0,03927524 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,02373989 0,03924002 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,02373989 0,03920486 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,02373989 0,03916976 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,02373989 0,03913473 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,02373989 0,03909975 ! phospholipid transport GO:0015914 15 15 0,000 0,02373989 0,03906484 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,02373989 0,03902999 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,02373989 0,03899521 ! glutathione metabolic process GO:0006749 16 15 0,000 0,02373989 0,03896048 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,02373989 0,03892582 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,02373989 0,03889122 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,02373989 0,03885668 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,02373989 0,0388222 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,02373989 0,03878779 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,02373989 0,03875343 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,02373989 0,03871914 ! protein homooligomerization GO:0051260 15 15 0,000 0,02373989 0,0386849 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,02373989 0,03865073 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,02530418 0,04116118 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,02530418 0,04112488 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,02530418 0,04108865 ! circadian rhythm GO:0007623 16 16 0,000 0,02530418 0,04105248 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,02530418 0,04101637 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,02530418 0,04098033 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,02530418 0,04094435 ! vacuole organization GO:0007033 16 16 0,000 0,02530418 0,04090843 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,02530418 0,04087258 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,02530418 0,04083679 ! vesicle targeting GO:0006903 17 16 0,000 0,02530418 0,04080106 ! segmentation GO:0035282 17 16 0,000 0,02530418 0,0407654 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,02530418 0,04072979 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,02530418 0,04069425 ! iron ion homeostasis GO:0055072 16 16 0,000 0,02530418 0,04065877 ! positive regulation of cell development GO:0010720 16 16 0,000 0,02530418 0,04062336 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,02530418 0,040588 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,02530418 0,04055271 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,02530418 0,04051747 ! cell fate specification GO:0001708 16 16 0,000 0,02530418 0,0404823 ! pentose metabolic process GO:0019321 16 16 0,000 0,02530418 0,04044719 ! fatty acid transport GO:0015908 16 16 0,000 0,02530418 0,04041214 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,02530418 0,04037715 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,02530418 0,04034223 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,02530418 0,04030736 ! cofactor catabolic process GO:0051187 16 16 0,000 0,02530418 0,04027255 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,02530418 0,0402378 ! polyol metabolic process GO:0019751 16 16 0,000 0,02530418 0,04020311 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,02530418 0,04016849 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,02530418 0,04013392 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,02530418 0,04009941 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,02530418 0,04006496 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,02530418 0,04003057 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,02530418 0,03999624 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,02530418 0,03996196 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,02530418 0,03992775 ! regulation of coagulation GO:0050818 17 16 0,000 0,02530418 0,03989359 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,0268662 0,04232 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,0268662 0,04228386 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,0268662 0,04224778 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,0268662 0,04221177 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,0268662 0,04217581 ! myelination GO:0042552 17 17 0,000 0,0268662 0,04213992 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,0268662 0,04210408 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,0268662 0,04206831 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,0268662 0,0420326 ! leukocyte adhesion GO:0007159 17 17 0,000 0,0268662 0,04199695 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,0268662 0,04196136 ! sensory perception of smell GO:0007608 17 17 0,000 0,0268662 0,04192583 ! glucose transport GO:0015758 17 17 0,000 0,0268662 0,04189036 ! cell junction assembly GO:0034329 18 17 0,000 0,0268662 0,04185495 ! tissue remodeling GO:0048771 17 17 0,000 0,0268662 0,0418196 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,0268662 0,0417843 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,0268662 0,04174907 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,0268662 0,0417139 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,0268662 0,04167879 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,0268662 0,04164374 ! neural crest cell development GO:0014032 19 17 0,000 0,0268662 0,04160874 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,0268662 0,0415738 ! negative regulation of cell development GO:0010721 18 17 0,000 0,0268662 0,04153893 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,0268662 0,04150411 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,0268662 0,04146935 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,0268662 0,04143465 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,0268662 0,0414 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,0268662 0,04136541 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,0268662 0,04133089 ! pigmentation GO:0043473 17 17 0,000 0,0268662 0,04129641 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,0268662 0,041262 ! adult locomotory behavior GO:0008344 17 17 0,000 0,0268662 0,04122764 ! embryonic organ development GO:0048568 17 17 0,000 0,0268662 0,04119335 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,0268662 0,0411591 ! liver development GO:0001889 17 17 0,000 0,0268662 0,04112492 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,02842593 0,04347634 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,02842593 0,04344029 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,02842593 0,0434043 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,02842593 0,04336837 ! meiosis I GO:0007127 18 18 0,000 0,02842593 0,0433325 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,02842593 0,04329669 ! membrane docking GO:0022406 18 18 0,000 0,02842593 0,04326094 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,02842593 0,04322524 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,02842593 0,04318961 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,02842593 0,04315403 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,02842593 0,04311851 ! hexose transport GO:0008645 18 18 0,000 0,02842593 0,04308306 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,02842593 0,04304765 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,02842593 0,04301231 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,02842593 0,04297703 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,02842593 0,0429418 ! ceramide metabolic process GO:0006672 18 18 0,000 0,02842593 0,04290663 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,02842593 0,04287152 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,02842593 0,04283646 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,02842593 0,04280147 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,02842593 0,04276653 ! B cell differentiation GO:0030183 18 18 0,000 0,02842593 0,04273164 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,02842593 0,04269682 ! ensheathment of neurons GO:0007272 18 18 0,000 0,02842593 0,04266205 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,02842593 0,04262734 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,02842593 0,04259268 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,02842593 0,04255808 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,02842593 0,04252354 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,02842593 0,04248905 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,0299834 0,04478071 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,0299834 0,04474445 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,0299834 0,04470825 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,0299834 0,04467211 ! regulation of pH GO:0006885 19 19 0,000 0,0299834 0,04463603 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,0299834 0,0446 ! feeding behavior GO:0007631 19 19 0,000 0,0299834 0,04456403 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,0299834 0,04452812 ! peroxisome organization GO:0007031 19 19 0,000 0,0299834 0,04449227 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,0299834 0,04445648 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,0299834 0,04442074 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,0299834 0,04438506 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,0299834 0,04434944 ! metanephros development GO:0001656 19 19 0,000 0,0299834 0,04431387 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,0299834 0,04427837 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,0299834 0,04424292 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,0299834 0,04420752 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,0299834 0,04417218 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,0299834 0,0441369 ! peripheral nervous system development GO:0007422 19 19 0,000 0,0299834 0,04410168 ! regulation of protein stability GO:0031647 19 19 0,000 0,0299834 0,04406651 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,0299834 0,0440314 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,0299834 0,04399634 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,0299834 0,04396134 ! eye morphogenesis GO:0048592 19 19 0,000 0,0299834 0,04392639 ! regulation of cell shape GO:0008360 21 19 0,000 0,0299834 0,0438915 ! placenta development GO:0001890 19 19 0,000 0,0299834 0,04385667 ! response to heat GO:0009408 19 19 0,000 0,0299834 0,04382189 ! vesicle localization GO:0051648 20 19 0,000 0,0299834 0,04378716 ! regulation of muscle development GO:0048634 21 20 0,000 0,03153859 0,04602187 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,03153859 0,04598546 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,03153859 0,04594911 ! negative regulation of binding GO:0051100 21 20 0,000 0,03153859 0,04591281 ! organic ether metabolic process GO:0018904 20 20 0,000 0,03153859 0,04587658 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,03153859 0,0458404 ! neural tube development GO:0021915 21 20 0,000 0,03153859 0,04580427 ! nucleus organization GO:0006997 20 20 0,000 0,03153859 0,04576821 ! phagocytosis GO:0006909 21 20 0,000 0,03153859 0,0457322 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,03153859 0,04569624 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,03153859 0,04566035 ! protein targeting to membrane GO:0006612 22 20 0,000 0,03153859 0,04562451 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,03153859 0,04558872 ! chromatin remodeling GO:0006338 20 20 0,000 0,03153859 0,045553 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,03153859 0,04551732 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,03153859 0,04548171 ! lipid oxidation GO:0034440 20 20 0,000 0,03153859 0,04544615 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,03153859 0,04541064 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,03153859 0,04537519 ! RNA modification GO:0009451 20 20 0,000 0,03153859 0,0453398 ! single fertilization GO:0007338 21 20 0,000 0,03153859 0,04530446 ! regulation of B cell activation GO:0050864 20 20 0,000 0,03153859 0,04526918 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,03309152 0,04746122 ! mRNA catabolic process GO:0006402 21 21 0,000 0,03309152 0,04742431 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,03309152 0,04738746 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,03309152 0,04735067 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,03309152 0,04731394 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,03309152 0,04727726 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,03309152 0,04724064 ! Notch signaling pathway GO:0007219 22 21 0,000 0,03309152 0,04720408 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,03309152 0,04716757 ! ear morphogenesis GO:0042471 21 21 0,000 0,03309152 0,04713112 ! organic anion transport GO:0015711 21 21 0,000 0,03309152 0,04709472 ! cholesterol transport GO:0030301 21 21 0,000 0,03309152 0,04705838 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,03309152 0,0470221 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,03309152 0,04698588 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,03309152 0,0469497 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,03309152 0,04691359 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,03309152 0,04687753 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,03309152 0,04684153 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,03309152 0,04680558 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,03309152 0,04676968 ! regulation of proteolysis GO:0030162 21 21 0,000 0,03309152 0,04673384 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,03309152 0,04669806 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,03309152 0,04666233 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,03464218 0,04881157 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,03464218 0,04877428 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,03464218 0,04873705 ! sister chromatid segregation GO:0000819 22 22 0,000 0,03464218 0,04869988 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,03464218 0,04866276 ! regulation of ion transport GO:0043269 22 22 0,000 0,03464218 0,04862569 ! odontogenesis GO:0042476 22 22 0,000 0,03464218 0,04858869 ! cell junction organization GO:0034330 23 22 0,000 0,03464218 0,04855174 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,03464218 0,04851485 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,03464218 0,04847801 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,03464218 0,04844123 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,03464218 0,0484045 ! ovulation cycle process GO:0022602 22 22 0,000 0,03464218 0,04836783 ! spindle organization GO:0007051 22 22 0,000 0,03464218 0,04833122 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,03464218 0,04829466 ! cell chemotaxis GO:0060326 23 22 0,000 0,03464218 0,04825815 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,03464218 0,0482217 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,03464218 0,04818531 ! male sex differentiation GO:0046661 22 22 0,000 0,03464218 0,04814897 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,03464218 0,04811269 ! biopolymer methylation GO:0043414 22 22 0,000 0,03464218 0,04807646 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,03464218 0,04804028 ! detection of external stimulus GO:0009581 23 22 0,000 0,03464218 0,04800416 ! neuron migration GO:0001764 22 22 0,000 0,03464218 0,0479681 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,03464218 0,04793208 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,03464218 0,04789613 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,03464218 0,04786022 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,03464218 0,04782437 ! aerobic respiration GO:0009060 22 22 0,000 0,03464218 0,04778858 ! cytokine production GO:0001816 22 22 0,000 0,03464218 0,04775283 ! cytokinesis GO:0000910 23 22 0,000 0,03464218 0,04771714 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,03464218 0,04768151 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,03619058 0,04977555 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,03619058 0,04973843 ! viral infectious cycle GO:0019058 23 23 0,000 0,03619058 0,04970137 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,03619058 0,04966436 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,03619058 0,04962741 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,03619058 0,04959051 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,03619058 0,04955367 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,03619058 0,04951688 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,03619058 0,04948015 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,03619058 0,04944347 ! endocrine system development GO:0035270 23 23 0,000 0,03619058 0,04940684 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,03619058 0,04937027 ! female gonad development GO:0008585 23 23 0,000 0,03619058 0,04933376 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,03619058 0,0492973 ! lipid homeostasis GO:0055088 23 23 0,000 0,03619058 0,04926089 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,03619058 0,04922453 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,03619058 0,04918823 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,03619058 0,04915198 ! cell projection assembly GO:0030031 25 23 0,000 0,03619058 0,04911579 ! mitochondrial transport GO:0006839 24 24 0,000 0,03773672 0,05117644 ! regulation of action potential GO:0001508 24 24 0,000 0,03773672 0,05113881 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,03773672 0,05110124 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,03773672 0,05106372 ! glucose homeostasis GO:0042593 24 24 0,000 0,03773672 0,05102625 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,03773672 0,05098884 ! T cell differentiation GO:0030217 24 24 0,000 0,03773672 0,05095149 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,03773672 0,05091419 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,03773672 0,05087694 ! ovulation cycle GO:0042698 24 24 0,000 0,03773672 0,05083975 ! fertilization GO:0009566 25 24 0,000 0,03773672 0,05080262 ! maintenance of protein location GO:0045185 25 24 0,000 0,03773672 0,05076553 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,03773672 0,05072851 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,03773672 0,05069153 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,03773672 0,05065461 ! glucan metabolic process GO:0044042 25 24 0,000 0,03773672 0,05061775 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,03928061 0,0526503 ! negative regulation of secretion GO:0051048 26 25 0,000 0,03928061 0,05261204 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,03928061 0,05257383 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,03928061 0,05253568 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,03928061 0,05249758 ! cellular component disassembly GO:0022411 26 25 0,000 0,03928061 0,05245954 ! endosome transport GO:0016197 25 25 0,000 0,03928061 0,05242156 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,03928061 0,05238362 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,03928061 0,05234575 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,03928061 0,05230792 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,03928061 0,05227016 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,03928061 0,05223244 ! excretion GO:0007588 25 25 0,000 0,03928061 0,05219479 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,03928061 0,05215718 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,03928061 0,05211963 ! gastrulation GO:0007369 25 25 0,000 0,03928061 0,05208214 ! heart morphogenesis GO:0003007 25 25 0,000 0,03928061 0,05204469 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,03928061 0,0520073 ! regulation of endocytosis GO:0030100 25 25 0,000 0,03928061 0,05196997 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,03928061 0,05193269 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,03928061 0,05189546 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,03928061 0,05185829 ! positive regulation of binding GO:0051099 27 26 0,000 0,04082225 0,05385498 ! positive regulation of defense response GO:0031349 26 26 0,000 0,04082225 0,05381645 ! glycolysis GO:0006096 26 26 0,000 0,04082225 0,05377799 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,04082225 0,05373957 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,04082225 0,05370122 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,04082225 0,05366291 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,04082225 0,05362466 ! cellular defense response GO:0006968 26 26 0,000 0,04082225 0,05358647 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,04082225 0,05354833 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,04082225 0,05351024 ! double-strand break repair GO:0006302 27 26 0,000 0,04082225 0,05347221 ! regulation of protein secretion GO:0050708 26 26 0,000 0,04082225 0,05343423 ! germ cell development GO:0007281 27 26 0,000 0,04082225 0,05339631 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,04082225 0,05335844 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,04082225 0,05332063 ! maintenance of location in cell GO:0051651 27 26 0,000 0,04082225 0,05328286 ! synapse organization GO:0050808 26 26 0,000 0,04082225 0,05324515 ! chloride transport GO:0006821 27 27 0,000 0,04236163 0,05521393 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,04236163 0,05517491 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,04236163 0,05513594 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,04236163 0,05509703 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,04236163 0,05505817 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,04236163 0,05501937 ! peptide metabolic process GO:0006518 29 27 0,000 0,04236163 0,05498063 ! activation of caspase activity GO:0006919 27 27 0,000 0,04236163 0,05494194 ! mesenchymal cell development GO:0014031 29 27 0,000 0,04236163 0,0549033 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,04236163 0,05486472 ! defense response to bacterium GO:0042742 27 27 0,000 0,04236163 0,05482619 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,04236163 0,05478771 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,04236163 0,05474929 ! cell growth GO:0016049 27 27 0,000 0,04236163 0,05471093 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,04389877 0,05665647 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,04389877 0,05661682 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,04389877 0,05657723 ! carbohydrate transport GO:0008643 28 28 0,000 0,04389877 0,05653769 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,04389877 0,05649821 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,04389877 0,05645879 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,04389877 0,05641942 ! histone modification GO:0016570 28 28 0,000 0,04389877 0,0563801 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,04389877 0,05634084 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,04389877 0,05630163 ! cartilage development GO:0051216 29 28 0,000 0,04389877 0,05626248 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,04543367 0,0581892 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,04543367 0,05814879 ! viral reproductive process GO:0022415 29 29 0,000 0,04543367 0,05810844 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,04543367 0,05806814 ! leukocyte migration GO:0050900 30 29 0,000 0,04543367 0,0580279 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,04543367 0,05798771 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,04543367 0,05794758 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,04543367 0,05790751 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,04543367 0,05786749 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,04543367 0,05782753 ! tRNA processing GO:0008033 29 29 0,000 0,04543367 0,05778762 ! adult behavior GO:0030534 30 29 0,000 0,04543367 0,05774776 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,04543367 0,05770796 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,04543367 0,05766822 ! response to UV GO:0009411 29 29 0,000 0,04543367 0,05762853 ! transition metal ion transport GO:0000041 31 30 0,000 0,04696633 0,0595316 ! RNA catabolic process GO:0006401 30 30 0,000 0,04696633 0,05949068 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,04696633 0,05944982 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,04696633 0,05940902 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,04696633 0,05936827 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,04696633 0,05932758 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,04696633 0,05928695 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,04696633 0,05924637 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,04696633 0,05920584 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,04696633 0,05916537 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,04696633 0,05912496 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,04696633 0,0590846 ! response to temperature stimulus GO:0009266 30 30 0,000 0,04696633 0,0590443 ! regulation of ossification GO:0030278 30 30 0,000 0,04696633 0,05900405 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,04696633 0,05896386 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,04696633 0,05892372 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,04696633 0,05888363 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,04696633 0,0588436 ! vesicle organization GO:0016050 30 30 0,000 0,04696633 0,05880363 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,04696633 0,05876371 ! establishment of organelle localization GO:0051656 31 30 0,000 0,04696633 0,05872384 ! regulation of translational initiation GO:0006446 31 31 0,000 0,04849675 0,06059627 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,04849675 0,06055522 ! membrane fusion GO:0006944 31 31 0,000 0,04849675 0,06051422 ! B cell activation GO:0042113 31 31 0,000 0,04849675 0,06047328 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,04849675 0,06043239 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,04849675 0,06039156 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,04849675 0,06035078 ! ion transmembrane transport GO:0034220 31 31 0,000 0,04849675 0,06031006 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,04849675 0,06026939 ! digestion GO:0007586 31 31 0,000 0,04849675 0,06022878 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,04849675 0,06018822 ! regulation of DNA replication GO:0006275 32 31 0,000 0,04849675 0,06014772 ! regulation of heart contraction GO:0008016 31 31 0,000 0,04849675 0,06010727 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,04849675 0,06006687 ! camera-type eye development GO:0043010 31 31 0,000 0,04849675 0,06002653 ! extracellular matrix organization GO:0030198 31 31 0,000 0,04849675 0,05998624 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,04849675 0,05994601 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,04849675 0,05990583 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,04849675 0,05986571 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,04849675 0,05982564 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,05002493 0,06166953 ! cell redox homeostasis GO:0045454 32 32 0,000 0,05002493 0,06162831 ! muscle fiber development GO:0048747 32 32 0,000 0,05002493 0,06158714 ! glucose catabolic process GO:0006007 32 32 0,000 0,05002493 0,06154603 ! lipid modification GO:0030258 32 32 0,000 0,05002493 0,06150497 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,05002493 0,06146397 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,05002493 0,06142302 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,05002493 0,06138212 ! cell maturation GO:0048469 32 32 0,000 0,05002493 0,06134128 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,05002493 0,0613005 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,05002493 0,06125977 ! nuclear export GO:0051168 32 32 0,000 0,05002493 0,06121909 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,05002493 0,06117847 ! kidney development GO:0001822 32 32 0,000 0,05002493 0,0611379 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,05002493 0,06109738 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,05002493 0,06105692 ! maintenance of location GO:0051235 33 32 0,000 0,05002493 0,06101651 ! negative regulation of cell size GO:0045792 33 33 0,000 0,05155088 0,06283616 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,05155088 0,06279463 ! amino acid transport GO:0006865 33 33 0,000 0,05155088 0,06275316 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,05155088 0,06271174 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,05155088 0,06267037 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,05155088 0,06262906 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,05155088 0,0625878 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,05155088 0,0625466 ! regulation of actin filament length GO:0030832 34 34 0,000 0,05307461 0,06435296 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,05307461 0,06431065 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,05307461 0,0642684 ! response to metal ion GO:0010038 34 34 0,000 0,05307461 0,0642262 ! ear development GO:0043583 34 34 0,000 0,05307461 0,06418406 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,05307461 0,06414197 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,05307461 0,06409994 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,05307461 0,06405796 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,05307461 0,06401604 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,05307461 0,06397417 ! secondary metabolic process GO:0019748 34 34 0,000 0,05307461 0,06393236 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,05307461 0,0638906 ! viral reproduction GO:0016032 34 34 0,000 0,05307461 0,06384889 ! detection of stimulus GO:0051606 36 34 0,000 0,05307461 0,06380724 ! acute inflammatory response GO:0002526 35 35 0,000 0,05459611 0,06559363 ! regulation of cellular component size GO:0032535 35 35 0,000 0,05459611 0,0655509 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,05459611 0,06550822 ! mesoderm development GO:0007498 35 35 0,000 0,05459611 0,0654656 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,05459611 0,06542303 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,05459611 0,06538052 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,05459611 0,06533807 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,05459611 0,06529567 ! inorganic anion transport GO:0015698 35 35 0,000 0,05459611 0,06525332 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,05459611 0,06521103 ! regulation of immune effector process GO:0002697 35 35 0,000 0,05459611 0,0651688 ! hydrogen transport GO:0006818 36 36 0,000 0,05611538 0,06693893 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,05611538 0,06689563 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,05611538 0,06685239 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,05611538 0,06680921 ! regulation of mitosis GO:0007088 37 36 0,000 0,05611538 0,06676608 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,05611538 0,066723 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,05611538 0,06667998 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,05611538 0,06663702 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,05611538 0,06659411 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,05611538 0,06655126 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,05611538 0,06650846 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,05611538 0,06646571 ! gonad development GO:0008406 36 36 0,000 0,05611538 0,06642303 ! regulation of lipase activity GO:0060191 36 36 0,000 0,05611538 0,06638039 ! activation of immune response GO:0002253 36 36 0,000 0,05611538 0,06633781 ! coagulation GO:0050817 39 36 0,000 0,05611538 0,06629529 GO:0007596|blood coagulation, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,05763244 0,06804394 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,05763244 0,06800037 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 0,000 0,05763244 0,06795687 ! lung development GO:0030324 38 37 0,000 0,05763244 0,06791342 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,05763244 0,06787002 ! eye development GO:0001654 37 37 0,000 0,05763244 0,06782668 ! negative regulation of growth GO:0045926 37 37 0,000 0,05763244 0,0677834 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,05763244 0,06774017 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,05763244 0,06769699 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,05763244 0,06765388 ! adaptive immune response GO:0002250 37 37 0,000 0,05763244 0,06761081 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,05914728 0,06934379 ! neurotransmitter transport GO:0006836 40 38 0,000 0,05914728 0,0692997 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,05914728 0,06925568 ! exocytosis GO:0006887 40 38 0,000 0,05914728 0,0692117 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,05914728 0,06916779 ! chromosome segregation GO:0007059 38 38 0,000 0,05914728 0,06912393 ! urogenital system development GO:0001655 38 38 0,000 0,05914728 0,06908012 ! hexose catabolic process GO:0019320 38 38 0,000 0,05914728 0,06903637 ! RNA elongation GO:0006354 38 38 0,000 0,05914728 0,06899268 ! meiotic cell cycle GO:0051321 38 38 0,000 0,05914728 0,06894904 ! axon guidance GO:0007411 39 38 0,000 0,05914728 0,06890546 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,05914728 0,06886193 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,05914728 0,06881846 ! hemostasis GO:0007599 42 39 0,000 0,0606599 0,07053388 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,0606599 0,07048941 ! activation of MAPK activity GO:0000187 39 39 0,000 0,0606599 0,07044499 ! respiratory tube development GO:0030323 40 39 0,000 0,0606599 0,07040063 ! response to unfolded protein GO:0006986 39 39 0,000 0,0606599 0,07035633 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,0606599 0,07031208 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,0606599 0,07026788 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,0606599 0,07022374 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,0606599 0,07017966 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,0606599 0,07013563 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,0606599 0,07009166 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,0606599 0,07004775 ! respiratory system development GO:0060541 40 39 0,000 0,0606599 0,07000388 ! developmental maturation GO:0021700 39 39 0,000 0,0606599 0,06996008 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,0606599 0,06991632 ! protein oligomerization GO:0051259 39 39 0,000 0,0606599 0,06987263 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,0606599 0,06982898 ! DNA catabolic process GO:0006308 41 40 0,000 0,06217032 0,07152303 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,06217032 0,07147841 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,06217032 0,07143385 ! organelle localization GO:0051640 41 40 0,000 0,06217032 0,07138934 ! cell cycle checkpoint GO:0000075 42 41 0,000 0,06367852 0,07307566 ! amine catabolic process GO:0009310 42 41 0,000 0,06367852 0,07303019 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,06367852 0,07298477 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,06367852 0,07293941 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,06367852 0,07289411 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,06367852 0,07284886 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,06367852 0,07280367 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,06518452 0,07447928 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,06518452 0,07443313 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,06518452 0,07438704 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,06518452 0,07434101 ! protein ubiquitination GO:0016567 43 42 0,000 0,06518452 0,07429504 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,06518452 0,07424912 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,06518452 0,07420326 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,06518452 0,07415745 ! reproductive structure development GO:0048608 43 43 0,000 0,06668832 0,07582145 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,06668832 0,07577471 ! alcohol catabolic process GO:0046164 43 43 0,000 0,06668832 0,07572802 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,06668832 0,07568139 ! humoral immune response GO:0006959 44 44 0,000 0,06818992 0,07733786 ! mRNA transport GO:0051028 44 44 0,000 0,06818992 0,0772903 ! protein import into nucleus GO:0006606 44 44 0,000 0,06818992 0,07724279 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,06818992 0,07719534 ! vitamin metabolic process GO:0006766 44 44 0,000 0,06818992 0,07714796 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,06818992 0,07710063 ! amine biosynthetic process GO:0009309 46 45 0,000 0,06968932 0,07874765 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,06968932 0,0786994 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,06968932 0,07865121 ! regulation of DNA binding GO:0051101 47 45 0,000 0,06968932 0,07860307 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,06968932 0,078555 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,06968932 0,07850698 ! nuclear import GO:0051170 45 45 0,000 0,06968932 0,07845902 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,06968932 0,07841112 ! protein processing GO:0016485 45 45 0,000 0,06968932 0,07836328 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,07118653 0,07999803 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,07118653 0,07994928 ! tube morphogenesis GO:0035239 47 46 0,000 0,07118653 0,07990059 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,07118653 0,07985196 ! regulation of membrane potential GO:0042391 46 46 0,000 0,07118653 0,07980339 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,07268155 0,08142984 ! regulation of blood pressure GO:0008217 48 47 0,000 0,07268155 0,08138037 ! sex differentiation GO:0007548 47 47 0,000 0,07268155 0,08133096 ! amine transport GO:0015837 47 47 0,000 0,07268155 0,08128161 ! rhythmic process GO:0048511 47 47 0,000 0,07268155 0,08123232 ! regulation of catabolic process GO:0009894 48 47 0,000 0,07268155 0,08118308 ! calcium ion transport GO:0006816 48 48 0,000 0,07417438 0,08280035 ! actin filament organization GO:0007015 50 48 0,000 0,07417438 0,08275023 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,07417438 0,08270017 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,07417438 0,08265017 ! protein localization in nucleus GO:0034504 48 48 0,000 0,07417438 0,08260023 ! leukocyte differentiation GO:0002521 50 49 0,000 0,07566502 0,08420932 ! gland development GO:0048732 51 49 0,000 0,07566502 0,0841585 ! cell cycle arrest GO:0007050 49 49 0,000 0,07566502 0,08410774 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,07566502 0,08405704 ! divalent metal ion transport GO:0070838 49 49 0,000 0,07566502 0,0840064 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,07566502 0,08395583 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,07566502 0,08390531 ! response to bacterium GO:0009617 50 49 0,000 0,07566502 0,08385486 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,07566502 0,08380447 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,07566502 0,08375413 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,07566502 0,08370386 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,07715348 0,08529926 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,07715348 0,08524812 ! negative regulation of transport GO:0051051 51 50 0,000 0,07715348 0,08519704 ! chromatin assembly GO:0031497 50 50 0,000 0,07715348 0,08514603 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,07715348 0,08509507 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,07715348 0,08504418 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,07715348 0,08499335 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,07715348 0,08494257 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,07715348 0,08489186 ! transcription initiation GO:0006352 50 50 0,000 0,07715348 0,08484121 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,07715348 0,08479062 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,07715348 0,08474009 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,07863976 0,08632108 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,07863976 0,08626969 ! positive regulation of immune response GO:0050778 51 51 0,000 0,07863976 0,08621837 ! rRNA metabolic process GO:0016072 51 51 0,000 0,07863976 0,08616711 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,07863976 0,08611592 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,07863976 0,08606478 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,07863976 0,0860137 ! protein maturation GO:0051604 51 51 0,000 0,07863976 0,08596268 ! RNA localization GO:0006403 52 52 0,000 0,08012387 0,08753307 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,08012387 0,08748122 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,08012387 0,08742942 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,08012387 0,08737769 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,08012387 0,08732602 ! sodium ion transport GO:0006814 53 53 0,000 0,0816058 0,08888859 ! tRNA metabolic process GO:0006399 53 53 0,000 0,0816058 0,08883609 ! response to hypoxia GO:0001666 53 53 0,000 0,0816058 0,08878365 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,0816058 0,08873127 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,0816058 0,08867895 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,0816058 0,08862669 ! regulation of T cell activation GO:0050863 53 53 0,000 0,0816058 0,0885745 ! regulation of protein transport GO:0051223 53 53 0,000 0,0816058 0,08852236 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,08308557 0,09007453 ! response to oxygen levels GO:0070482 55 54 0,000 0,08308557 0,09002157 ! response to virus GO:0009615 54 54 0,000 0,08308557 0,08996868 ! hormone metabolic process GO:0042445 55 54 0,000 0,08308557 0,08991585 ! sulfur metabolic process GO:0006790 55 54 0,000 0,08308557 0,08986309 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,08308557 0,08981038 ! nucleosome organization GO:0034728 55 55 0,000 0,08456316 0,09135399 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,08456316 0,09130047 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,08456316 0,09124702 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,08456316 0,09119362 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,08456316 0,0911403 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,08603859 0,09267628 ! reproductive developmental process GO:0003006 56 56 0,000 0,08603859 0,09262215 ! extracellular structure organization GO:0043062 56 56 0,000 0,08603859 0,09256808 ! regulation of nervous system development GO:0051960 57 56 0,000 0,08603859 0,09251407 ! regulation of binding GO:0051098 60 57 0,000 0,08751186 0,09404335 ! ATP metabolic process GO:0046034 57 57 0,000 0,08751186 0,09398855 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,08751186 0,09393381 ! regulation of protein localization GO:0032880 58 57 0,000 0,08751186 0,09387913 ! innate immune response GO:0045087 58 58 0,000 0,08898297 0,09540175 ! dephosphorylation GO:0016311 60 59 0,000 0,09045192 0,09692028 ! carboxylic acid transport GO:0046942 59 59 0,000 0,09045192 0,09686396 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,09045192 0,09680771 ! regulation of cell development GO:0060284 60 59 0,000 0,09045192 0,09675153 ! sterol metabolic process GO:0016125 59 59 0,000 0,09045192 0,09669541 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,09045192 0,09663935 ! protein localization in organelle GO:0033365 59 59 0,000 0,09045192 0,09658336 ! immune effector process GO:0002252 59 59 0,000 0,09045192 0,09652744 ! potassium ion transport GO:0006813 60 60 0,000 0,09191871 0,09803599 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,09191871 0,09797929 ! protein polymerization GO:0051258 65 60 0,000 0,09191871 0,09792265 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,09338336 0,0994255 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,09338336 0,09936809 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,09338336 0,09931075 ! lipid transport GO:0006869 62 62 0,000 0,09484586 0,10080791 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,09484586 0,10074981 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,09484586 0,10069178 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,09484586 0,10063381 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,09484586 0,1005759 ! protein import GO:0017038 62 62 0,000 0,09484586 0,10051807 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,09484586 0,1004603 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,09484586 0,1004026 ! regulation of secretion GO:0051046 65 63 0,000 0,09630622 0,10188999 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,09630622 0,10183153 ! glucose metabolic process GO:0006006 63 63 0,000 0,09630622 0,10177314 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,09630622 0,10171482 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,09630622 0,10165656 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,09776443 0,10313671 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,09776443 0,10307771 ! angiogenesis GO:0001525 65 64 0,000 0,09776443 0,10301878 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,09776443 0,10295991 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,09776443 0,10290111 ! anion transport GO:0006820 65 65 0,000 0,0992205 0,10437408 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,0992205 0,10431454 ! regulation of hormone levels GO:0010817 66 65 0,000 0,0992205 0,10425506 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,10067444 0,1057225 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,10067444 0,10566229 ! DNA packaging GO:0006323 66 66 0,000 0,10067444 0,10560215 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,10067444 0,10554209 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,10067444 0,10548208 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,10067444 0,10542215 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,10212624 0,10688169 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,10212624 0,10682103 ! muscle contraction GO:0006936 67 67 0,000 0,10212624 0,10676044 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,10212624 0,10669992 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,10357591 0,1081532 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,10357591 0,10809196 ! regulation of translation GO:0006417 69 69 0,000 0,10502345 0,10954059 ! sensory perception of sound GO:0007605 71 69 0,000 0,10502345 0,10947863 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,10502345 0,10941675 ! response to nutrient levels GO:0031667 69 69 0,000 0,10502345 0,10935493 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,10502345 0,10929318 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,10502345 0,1092315 ! positive regulation of transport GO:0051050 71 70 0,000 0,10646887 0,11067238 ! cell part morphogenesis GO:0032990 75 70 0,000 0,10646887 0,11060999 ! wound healing GO:0042060 74 70 0,000 0,10646887 0,11054768 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,10646887 0,11048543 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,10791217 0,11192016 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,10791217 0,11185721 ! regulation of cell migration GO:0030334 71 71 0,000 0,10791217 0,11179434 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,10791217 0,11173153 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,10791217 0,11166879 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,10791217 0,11160613 ! regulation of cell activation GO:0050865 71 71 0,000 0,10791217 0,11154354 ! secretion by cell GO:0032940 75 72 0,000 0,10935334 0,11296985 ! muscle system process GO:0003012 72 72 0,000 0,10935334 0,11290656 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,10935334 0,11284334 ! sensory organ development GO:0007423 72 72 0,000 0,10935334 0,1127802 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,10935334 0,11271712 ! regulation of cytokine production GO:0001817 72 72 0,000 0,10935334 0,11265411 ! electron transport chain GO:0022900 75 74 0,000 0,11222935 0,11555234 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,11222935 0,11548782 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,11366418 0,11689904 ! response to oxidative stress GO:0006979 76 75 0,000 0,11366418 0,11683384 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,11366418 0,11676872 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,11509691 0,11817471 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,11509691 0,11810891 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,11652752 0,11951042 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,11652752 0,11944395 ! regulation of protein modification process GO:0031399 79 78 0,000 0,11795604 0,12084101 ! microtubule-based movement GO:0007018 82 78 0,000 0,11795604 0,12077388 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,11795604 0,12070682 ! metal ion homeostasis GO:0055065 78 78 0,000 0,11795604 0,12063984 ! regulation of immune response GO:0050776 78 78 0,000 0,11795604 0,12057292 ! regulation of locomotion GO:0040012 79 79 0,000 0,11938246 0,12196334 ! nuclear transport GO:0051169 79 79 0,000 0,11938246 0,12189577 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 0,000 0,11938246 0,12182828 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,12080678 0,12321355 ! neuron projection development GO:0031175 85 80 0,000 0,12080678 0,1231454 ! MAPKKK cascade GO:0000165 82 81 0,000 0,122229 0,12452628 ! tube development GO:0035295 83 81 0,000 0,122229 0,12445748 ! lymphocyte activation GO:0046649 82 81 0,000 0,122229 0,12438876 ! lipid catabolic process GO:0016042 82 81 0,000 0,122229 0,12432011 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,12506718 0,12713668 ! ncRNA processing GO:0034470 83 83 0,000 0,12506718 0,1270666 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,12506718 0,12699659 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,12648313 0,12836366 ! regulation of cellular localization GO:0060341 86 85 0,000 0,12789701 0,12972712 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,12789701 0,12965577 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,12789701 0,12958449 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,12789701 0,12951329 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,1293088 0,13087102 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,1293088 0,13079919 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,1293088 0,13072744 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,1293088 0,13065577 ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,13212615 0,13342932 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,13212615 0,13335624 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,13353172 0,13470113 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,13633665 0,13745539 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,13633665 0,13738023 ! DNA replication GO:0006260 91 91 0,000 0,13633665 0,13730516 ! visual perception GO:0007601 93 92 0,000 0,13773602 0,13863871 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,13773602 0,13856303 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,13773602 0,13848744 ! regulation of response to stress GO:0080134 97 94 0,000 0,14052857 0,14121818 ! blood vessel development GO:0001568 95 94 0,000 0,14052857 0,14114123 ! pattern specification process GO:0007389 96 94 0,000 0,14052857 0,14106435 ! cofactor metabolic process GO:0051186 95 94 0,000 0,14052857 0,14098756 ! vasculature development GO:0001944 97 96 0,000 0,14331289 0,14370275 ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,14608902 0,14640677 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,14608902 0,14632721 ! blood circulation GO:0008015 99 98 0,000 0,14608902 0,14624772 GO:0003013|circulatory system process, ! response to other organism GO:0051707 101 100 0,000 0,14885696 0,14893777 ! hemopoiesis GO:0030097 104 100 0,000 0,14885696 0,14885696