pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/8607-10-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 7 5 2,000 5,557E-08 1,278E-04 GO:0019405|alditol catabolic process, ! cellular carbohydrate catabolic process GO:0044275 13 11 2,000 9,101E-07 1,047E-03 ! fructose metabolic process GO:0006000 20 16 2,000 3,07E-06 2,353E-03 ! alditol metabolic process GO:0019400 24 20 2,000 6,218E-06 3,575E-03 ! sperm motility GO:0030317 27 24 2,000 1,098E-05 5,053E-03 ! hexose biosynthetic process GO:0019319 35 29 2,000 1,971E-05 7,555E-03 ! monosaccharide biosynthetic process GO:0046364 38 32 2,000 2,665E-05 8,757E-03 ! Ras protein signal transduction GO:0007265 162 100 3,000 3,205E-05 9,213E-03 ! polyol metabolic process GO:0019751 44 34 2,000 3,208E-05 8,197E-03 ! glial cell fate commitment GO:0021781 12 5 1,000 3,235E-05 7,44E-03 ! keratinocyte differentiation GO:0030216 47 35 2,000 3,504E-05 7,326E-03 ! alcohol biosynthetic process GO:0046165 45 38 2,000 4,499E-05 8,624E-03 ! regulation of Rac protein signal transduction GO:0035020 8 6 1,000 4,847E-05 8,575E-03 ! blastocyst growth GO:0001832 15 6 1,000 4,847E-05 7,963E-03 ! epidermal cell differentiation GO:0009913 53 40 2,000 5,257E-05 8,06E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 1,000 9,027E-05 0,01297591 GO:0046579|positive regulation of Ras protein signal transduction, ! keratinocyte proliferation GO:0043616 12 8 1,000 9,027E-05 0,01221262 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 1,000 9,027E-05 0,01153414 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 1,447E-04 0,01752124 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,524E-04 0,01752811 ! negative regulation of kinase activity GO:0033673 100 58 2,000 1,605E-04 0,01758213 ! chromatin silencing GO:0006342 19 11 1,000 1,767E-04 0,0184735 ! negative regulation of transferase activity GO:0051348 105 61 2,000 1,865E-04 0,01865462 ! positive regulation of cell growth GO:0030307 16 12 1,000 2,118E-04 0,02029762 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 1,000 2,914E-04 0,02680529 ! epidermis morphogenesis GO:0048730 29 14 1,000 2,914E-04 0,02577432 ! negative regulation of caspase activity GO:0043154 20 14 1,000 2,914E-04 0,02481971 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,914E-04 0,0239333 ! positive regulation of cell size GO:0045793 20 15 1,000 3,358E-04 0,02663262 ! skin development GO:0043588 25 15 1,000 3,358E-04 0,02574486 ! embryonic hindlimb morphogenesis GO:0035116 25 15 1,000 3,358E-04 0,02491438 ! carbohydrate biosynthetic process GO:0016051 97 77 2,000 3,717E-04 0,0267157 ! alcohol catabolic process GO:0046164 104 80 2,000 4,159E-04 0,02898886 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 4,34E-04 0,0293555 ! inactivation of MAPK activity GO:0000188 27 17 1,000 4,34E-04 0,02851677 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 1,000 4,876E-04 0,03115459 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 4,876E-04 0,03031257 ! visual learning GO:0008542 35 18 1,000 4,876E-04 0,02951487 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 5,444E-04 0,03210467 ! hindlimb morphogenesis GO:0035137 32 20 1,000 6,042E-04 0,03474033 ! carbohydrate catabolic process GO:0016052 121 93 2,000 6,464E-04 0,03626224 ! visual behavior GO:0007632 39 21 1,000 6,67E-04 0,03652701 ! cell aging GO:0007569 32 21 1,000 6,67E-04 0,03567754 ! blastocyst development GO:0001824 37 22 1,000 7,329E-04 0,03830956 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 8,018E-04 0,04097884 ! osteoblast differentiation GO:0001649 40 23 1,000 8,018E-04 0,040088 ! cell fate determination GO:0001709 45 23 1,000 8,018E-04 0,03923506 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 8,736E-04 0,04186233 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 1,026E-03 0,04817821 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 1,107E-03 0,05093362 ! gene silencing GO:0016458 41 27 1,000 1,107E-03 0,04993492 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 1,191E-03 0,05268172 ! hindbrain development GO:0030902 45 30 1,000 1,368E-03 0,05934624 ! glial cell differentiation GO:0010001 55 31 1,000 1,46E-03 0,06219324 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 1,556E-03 0,06505898 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 1,654E-03 0,06794203 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 1,654E-03 0,06675006 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 1,756E-03 0,06961965 ! learning GO:0007612 67 37 1,000 2,077E-03 0,08097158 ! gliogenesis GO:0042063 71 38 1,000 2,19E-03 0,08394968 ! striated muscle cell differentiation GO:0051146 54 38 1,000 2,19E-03 0,08257345 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 2,306E-03 0,08553544 ! chromatin remodeling GO:0006338 68 39 1,000 2,306E-03 0,08417774 ! developmental growth GO:0048589 62 39 1,000 2,306E-03 0,08286246 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 2,424E-03 0,08578385 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 2,67E-03 0,09304499 ! response to insulin stimulus GO:0032868 63 43 1,000 2,797E-03 0,09601775 ! covalent chromatin modification GO:0016569 75 47 1,000 3,333E-03 0,11273927 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 3,333E-03 0,11110536 ! positive regulation of growth GO:0045927 67 50 1,000 3,764E-03 0,12368353 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 3,913E-03 0,12677421 ! aging GO:0007568 79 52 1,000 4,065E-03 0,12986598 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 4,7E-03 0,14808256 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 4,865E-03 0,15122123 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 5,377E-03 0,16490755 GO:0035113|embryonic appendage morphogenesis, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 5,553E-03 0,16806287 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 5,732E-03 0,17121464 ! appendage morphogenesis GO:0035107 93 64 1,000 6,097E-03 0,17978265 GO:0035108|limb morphogenesis, ! regulation of caspase activity GO:0043281 97 65 1,000 6,283E-03 0,18293384 ! appendage development GO:0048736 94 65 1,000 6,283E-03 0,18064717 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 6,283E-03 0,17841696 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 6,283E-03 0,17624114 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 6,664E-03 0,18466328 ! learning or memory GO:0007611 123 68 1,000 6,858E-03 0,18778048 ! positive regulation of ligase activity GO:0051351 99 69 1,000 7,055E-03 0,19089355 ! eye development GO:0001654 111 70 1,000 7,254E-03 0,19400239 ! muscle cell differentiation GO:0042692 104 71 1,000 7,456E-03 0,19710689 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 7,456E-03 0,19486704 ! regulation of peptidase activity GO:0052547 106 72 1,000 7,66E-03 0,19795744 ! regulation of synaptic transmission GO:0050804 109 72 1,000 7,66E-03 0,19575791 ! mitochondrion organization GO:0007005 104 73 1,000 7,867E-03 0,19883431 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 8,076E-03 0,20190661 ! regulation of ligase activity GO:0051340 114 75 1,000 8,288E-03 0,20497472 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 8,719E-03 0,21334371 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 8,719E-03 0,21109799 ! regulation of cyclase activity GO:0031279 132 78 1,000 8,939E-03 0,21415297 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 9,12E-03 0,21624425 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 9,12E-03 0,21403767 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 9,12E-03 0,21187568 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 9,12E-03 0,20975692 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 9,12E-03 0,20768012 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,12E-03 0,20564404 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 9,12E-03 0,2036475 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 9,12E-03 0,20168935 ! sleep GO:0030431 11 5 0,000 9,12E-03 0,1997685 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,12E-03 0,19788389 ! nucleotide-sugar transport GO:0015780 8 5 0,000 9,12E-03 0,19603451 ! regulation of interferon-beta production GO:0032648 5 5 0,000 9,12E-03 0,19421937 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 9,12E-03 0,19243754 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 9,12E-03 0,19068811 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 9,12E-03 0,1889702 ! tongue development GO:0043586 6 5 0,000 9,12E-03 0,18728297 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 9,12E-03 0,18562559 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 9,12E-03 0,1839973 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 9,12E-03 0,18239732 ! cobalt ion transport GO:0006824 9 5 0,000 9,12E-03 0,18082493 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 9,12E-03 0,17927942 ! SMAD protein complex assembly GO:0007183 9 5 0,000 9,12E-03 0,1777601 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 9,12E-03 0,17626632 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 9,12E-03 0,17479743 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 9,12E-03 0,17335283 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 9,12E-03 0,1719319 ! embryonic camera-type eye development GO:0031076 8 5 0,000 9,12E-03 0,17053408 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 9,12E-03 0,16915881 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 9,12E-03 0,16780554 ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,12E-03 0,16647375 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 9,12E-03 0,16516293 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 9,12E-03 0,16387259 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 9,12E-03 0,16260226 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 9,12E-03 0,16135148 ! positive regulation of histone modification GO:0031058 5 5 0,000 9,12E-03 0,16011979 ! malate metabolic process GO:0006108 7 5 0,000 9,12E-03 0,15890676 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 9,12E-03 0,15771197 ! behavioral response to pain GO:0048266 7 5 0,000 9,12E-03 0,15653502 ! clathrin coat assembly GO:0048268 11 5 0,000 9,12E-03 0,1553755 ! phototransduction, visible light GO:0007603 6 5 0,000 9,12E-03 0,15423303 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,12E-03 0,15310724 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 9,12E-03 0,15199777 ! mating behavior GO:0007617 6 5 0,000 9,12E-03 0,15090426 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 9,12E-03 0,14982637 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 9,12E-03 0,14876377 ! rhythmic behavior GO:0007622 12 5 0,000 9,12E-03 0,14771614 ! copulation GO:0007620 7 5 0,000 9,12E-03 0,14668316 ! protein maturation by protein folding GO:0022417 12 5 0,000 9,12E-03 0,14566453 ! embryonic hemopoiesis GO:0035162 10 5 0,000 9,12E-03 0,14465995 ! regulation of potassium ion transport GO:0043266 9 5 0,000 9,12E-03 0,14366912 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 9,12E-03 0,14269178 ! apoptotic cell clearance GO:0043277 13 5 0,000 9,12E-03 0,14172765 ! lipoprotein particle clearance GO:0034381 9 5 0,000 9,12E-03 0,14077646 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 9,12E-03 0,13983795 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,12E-03 0,13891187 ! response to protozoan GO:0001562 9 5 0,000 9,12E-03 0,13799797 ! positive regulation of glycolysis GO:0045821 11 5 0,000 9,12E-03 0,13709603 ! lymph vessel development GO:0001945 7 5 0,000 9,12E-03 0,13620579 ! endochondral ossification GO:0001958 12 5 0,000 9,12E-03 0,13532705 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 9,12E-03 0,13445956 ! parathyroid gland development GO:0060017 8 5 0,000 9,12E-03 0,13360313 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 9,12E-03 0,13275755 ! anagen GO:0042640 6 5 0,000 9,12E-03 0,13192259 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 9,12E-03 0,13109808 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 9,12E-03 0,1302838 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 9,12E-03 0,12947958 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 9,12E-03 0,12868523 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 9,12E-03 0,12790056 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 9,12E-03 0,12712541 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 9,12E-03 0,12635959 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 9,12E-03 0,12560295 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 9,12E-03 0,12485531 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 9,12E-03 0,12411652 ! cardiac muscle fiber development GO:0048739 7 5 0,000 9,12E-03 0,12338642 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 9,12E-03 0,12266487 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 9,12E-03 0,1219517 ! neutrophil mediated immunity GO:0002446 6 5 0,000 9,12E-03 0,12124678 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 9,12E-03 0,12054995 ! ovulation GO:0030728 6 5 0,000 9,12E-03 0,1198611 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 9,12E-03 0,11918007 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 9,12E-03 0,11850674 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 9,12E-03 0,11784097 ! response to pH GO:0009268 9 5 0,000 9,12E-03 0,11718264 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 9,12E-03 0,11653162 ! proline biosynthetic process GO:0006561 6 5 0,000 9,12E-03 0,1158878 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 9,12E-03 0,11525106 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 9,12E-03 0,11462127 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 9,12E-03 0,11399833 ! polyol biosynthetic process GO:0046173 5 5 0,000 9,12E-03 0,11338212 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 9,12E-03 0,11277254 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 9,12E-03 0,11216948 ! sister chromatid cohesion GO:0007062 9 5 0,000 9,12E-03 0,11157283 ! nerve growth factor processing GO:0032455 7 5 0,000 9,12E-03 0,1109825 ! urea metabolic process GO:0019627 6 5 0,000 9,12E-03 0,11039838 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 9,12E-03 0,10982038 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 9,12E-03 0,1092484 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 9,12E-03 0,10868234 ! neutrophil activation GO:0042119 5 5 0,000 9,12E-03 0,10812212 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 9,12E-03 0,10756765 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 9,12E-03 0,10701884 ! response to food GO:0032094 5 5 0,000 9,12E-03 0,10647559 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 9,12E-03 0,10593784 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,12E-03 0,10540549 ! paraxial mesoderm development GO:0048339 9 5 0,000 9,12E-03 0,10487846 ! forebrain neuron development GO:0021884 7 5 0,000 9,12E-03 0,10435668 ! melanosome organization GO:0032438 7 5 0,000 9,12E-03 0,10384006 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 9,12E-03 0,10332853 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 9,12E-03 0,10282202 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 9,12E-03 0,10232045 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,12E-03 0,10182375 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 9,12E-03 0,10133185 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 9,12E-03 0,10084467 ! nucleoside transport GO:0015858 6 5 0,000 9,12E-03 0,10036216 ! nucleoside salvage GO:0043174 7 5 0,000 9,12E-03 0,09988425 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 9,12E-03 0,09941086 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,12E-03 0,09894194 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 9,12E-03 0,09847743 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 9,12E-03 0,09801725 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 9,12E-03 0,09756136 ! early endosome to late endosome transport GO:0045022 11 5 0,000 9,12E-03 0,09710969 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,12E-03 0,09666218 ! depyrimidination GO:0045008 8 5 0,000 9,12E-03 0,09621877 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 9,12E-03 0,09577942 ! 5S class rRNA transcription GO:0042791 8 5 0,000 9,12E-03 0,09534406 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 9,12E-03 0,09491263 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,12E-03 0,0944851 ! neuronal ion channel clustering GO:0045161 7 5 0,000 9,12E-03 0,0940614 ! sodium ion homeostasis GO:0055078 6 5 0,000 9,12E-03 0,09364148 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 9,12E-03 0,0932253 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 9,12E-03 0,0928128 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 9,12E-03 0,09240393 ! monocyte differentiation GO:0030224 8 5 0,000 9,12E-03 0,09199865 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 9,12E-03 0,09159691 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 9,12E-03 0,09119866 ! centrosome duplication GO:0051298 5 5 0,000 9,12E-03 0,09080386 ! response to UV-C GO:0010225 6 5 0,000 9,12E-03 0,09041247 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 9,12E-03 0,09002443 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 9,12E-03 0,08963971 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 9,12E-03 0,08925826 ! regulation of dendrite development GO:0050773 12 5 0,000 9,12E-03 0,08888005 ! peptidyl-arginine modification GO:0018195 7 5 0,000 9,12E-03 0,08850503 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,12E-03 0,08813316 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 9,12E-03 0,0877644 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 9,12E-03 0,08739872 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 9,12E-03 0,08703607 ! regulation of dopamine secretion GO:0014059 12 5 0,000 9,12E-03 0,08667641 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 9,12E-03 0,08631972 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 9,12E-03 0,08596595 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 9,12E-03 0,08561507 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 9,12E-03 0,08526704 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 9,12E-03 0,08492183 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 9,12E-03 0,0845794 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 9,12E-03 0,08423973 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 9,12E-03 0,08390277 ! neural tube patterning GO:0021532 6 5 0,000 9,12E-03 0,08356849 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 9,12E-03 0,08323687 ! histone demethylation GO:0016577 9 5 0,000 9,12E-03 0,08290787 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 9,12E-03 0,08258147 ! regulation of sterol transport GO:0032371 7 5 0,000 9,12E-03 0,08225762 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 9,12E-03 0,0819363 ! enteric nervous system development GO:0048484 8 5 0,000 9,12E-03 0,08161748 ! establishment of planar polarity GO:0001736 6 5 0,000 9,12E-03 0,08130113 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 9,12E-03 0,08098723 ! muscle cell proliferation GO:0033002 8 5 0,000 9,12E-03 0,08067574 ! transcription termination GO:0006353 8 5 0,000 9,12E-03 0,08036664 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 9,12E-03 0,08005989 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 9,12E-03 0,07975548 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 9,12E-03 0,07945338 ! regulation of respiratory burst GO:0060263 8 5 0,000 9,12E-03 0,07915356 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 9,12E-03 0,07885599 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 9,12E-03 0,07856064 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 9,12E-03 0,07826751 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 9,12E-03 0,07797655 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 9,12E-03 0,07768775 ! apical protein localization GO:0045176 6 5 0,000 9,12E-03 0,07740108 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 9,12E-03 0,07711652 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 9,12E-03 0,07683404 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,12E-03 0,07655362 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 9,12E-03 0,07627524 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 9,12E-03 0,07599888 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 9,12E-03 0,07572452 ! triglyceride catabolic process GO:0019433 6 5 0,000 9,12E-03 0,07545213 ! glial cell migration GO:0008347 10 5 0,000 9,12E-03 0,07518169 ! determination of adult lifespan GO:0008340 8 5 0,000 9,12E-03 0,07491319 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 9,12E-03 0,07464659 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 9,12E-03 0,07438189 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 9,12E-03 0,07411905 ! somatic stem cell maintenance GO:0035019 13 5 0,000 9,12E-03 0,07385807 ! cerebellar cortex formation GO:0021697 6 5 0,000 9,12E-03 0,07359892 ! neural plate development GO:0001840 6 5 0,000 9,12E-03 0,07334158 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 9,12E-03 0,07308604 ! regulation of sensory perception GO:0051931 6 5 0,000 9,12E-03 0,07283226 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 9,12E-03 0,07258025 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 9,12E-03 0,07232997 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 9,12E-03 0,07208142 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 9,12E-03 0,07183456 ! sensory cilium assembly GO:0035058 6 5 0,000 9,12E-03 0,07158939 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 9,12E-03 0,07134589 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 9,12E-03 0,07110404 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 9,12E-03 0,07086382 ! spindle assembly GO:0051225 5 5 0,000 9,12E-03 0,07062523 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 9,12E-03 0,07038823 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 9,12E-03 0,07015282 ! protein amino acid prenylation GO:0018346 9 5 0,000 9,12E-03 0,06991897 ! organ regeneration GO:0031100 7 5 0,000 9,12E-03 0,06968668 ! NAD biosynthetic process GO:0009435 7 5 0,000 9,12E-03 0,06945593 ! carnitine metabolic process GO:0009437 5 5 0,000 9,12E-03 0,06922671 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 9,12E-03 0,06899899 ! cellular anion homeostasis GO:0030002 6 5 0,000 9,12E-03 0,06877276 GO:0055081|anion homeostasis, ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 9,16E-03 0,06885206 ! cellular respiration GO:0045333 107 79 1,000 9,16E-03 0,06862779 ! regulation of lyase activity GO:0051339 133 79 1,000 9,16E-03 0,06840497 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 9,385E-03 0,06985251 GO:0010498|proteasomal protein catabolic process, ! forebrain development GO:0030900 131 80 1,000 9,385E-03 0,06962718 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 9,611E-03 0,07107958 ! regulation of neurological system process GO:0031644 122 81 1,000 9,611E-03 0,07085176 ! ossification GO:0001503 134 82 1,000 9,84E-03 0,07230887 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,01007182 0,0737745 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,01078089 0,07871759 ! tRNA transcription GO:0009304 11 6 0,000 0,01093415 0,07958397 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01093415 0,07933292 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01093415 0,07908344 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01093415 0,07883553 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01093415 0,07858917 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01093415 0,07834435 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01093415 0,07810104 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01093415 0,07785924 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01093415 0,07761894 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01093415 0,07738011 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01093415 0,07714275 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01093415 0,07690684 ! prostate gland development GO:0030850 9 6 0,000 0,01093415 0,07667236 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01093415 0,07643932 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01093415 0,07620768 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01093415 0,07597745 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01093415 0,0757486 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01093415 0,07552113 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01093415 0,07529502 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01093415 0,07507025 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01093415 0,07484683 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01093415 0,07462473 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01093415 0,07440395 ! neuron adhesion GO:0007158 9 6 0,000 0,01093415 0,07418447 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01093415 0,07396628 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01093415 0,07374937 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01093415 0,07353373 ! signal peptide processing GO:0006465 8 6 0,000 0,01093415 0,07331934 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01093415 0,07310621 ! mRNA stabilization GO:0048255 15 6 0,000 0,01093415 0,0728943 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01093415 0,07268363 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01093415 0,07247416 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01093415 0,07226591 ! opsonization GO:0008228 8 6 0,000 0,01093415 0,07205884 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01093415 0,07185296 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01093415 0,07164825 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01093415 0,0714447 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01093415 0,07124231 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01093415 0,07104106 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01093415 0,07084094 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01093415 0,07064195 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01093415 0,07044408 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01093415 0,0702473 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01093415 0,07005163 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01093415 0,06985704 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01093415 0,06966353 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01093415 0,06947109 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01093415 0,06927971 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01093415 0,06908938 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01093415 0,0689001 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01093415 0,06871184 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01093415 0,06852462 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01093415 0,06833841 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01093415 0,06815321 ! thymic T cell selection GO:0045061 12 6 0,000 0,01093415 0,06796901 ! protein lipoylation GO:0009249 10 6 0,000 0,01093415 0,06778581 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01093415 0,06760359 ! pigment granule organization GO:0048753 11 6 0,000 0,01093415 0,06742235 ! drug transport GO:0015893 6 6 0,000 0,01093415 0,06724207 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01093415 0,06706276 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01093415 0,0668844 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01093415 0,06670699 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01093415 0,06653052 ! histidine metabolic process GO:0006547 6 6 0,000 0,01093415 0,06635497 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01093415 0,06618036 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01093415 0,06600665 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01093415 0,06583386 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01093415 0,06566197 ! adenohypophysis development GO:0021984 10 6 0,000 0,01093415 0,06549098 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01093415 0,06532087 ! hyperosmotic response GO:0006972 8 6 0,000 0,01093415 0,06515165 ! microtubule nucleation GO:0007020 10 6 0,000 0,01093415 0,06498329 ! ER overload response GO:0006983 7 6 0,000 0,01093415 0,06481581 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01093415 0,06464919 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01093415 0,06448342 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01093415 0,0643185 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01093415 0,06415443 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01093415 0,06399118 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01093415 0,06382877 ! response to dietary excess GO:0002021 7 6 0,000 0,01093415 0,06366718 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01093415 0,0635064 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01093415 0,06334644 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01093415 0,06318727 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01093415 0,06302891 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01093415 0,06287134 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01093415 0,06271455 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01093415 0,06255855 ! neuron apoptosis GO:0051402 8 6 0,000 0,01093415 0,06240331 ! organic alcohol transport GO:0015850 9 6 0,000 0,01093415 0,06224885 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01093415 0,06209515 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01093415 0,0619422 ! male sex determination GO:0030238 9 6 0,000 0,01093415 0,06179001 ! carnitine transport GO:0015879 8 6 0,000 0,01093415 0,06163857 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01093415 0,06148786 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01093415 0,06133789 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01093415 0,06118865 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01093415 0,06104013 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01093415 0,06089234 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01093415 0,06074525 ! parturition GO:0007567 12 6 0,000 0,01093415 0,06059888 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01093415 0,06045321 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01093415 0,06030824 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01093415 0,06016396 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01093415 0,06002037 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01093415 0,05987746 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01093415 0,05973524 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01093415 0,05959369 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01093415 0,0594528 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01093415 0,05931258 ! macrophage differentiation GO:0030225 10 6 0,000 0,01093415 0,05917302 ! astrocyte development GO:0014002 14 6 0,000 0,01093415 0,05903412 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01093415 0,05889587 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01093415 0,05875826 ! interaction with symbiont GO:0051702 8 6 0,000 0,01093415 0,05862129 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01093415 0,05848497 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01093415 0,05834927 ! eating behavior GO:0042755 6 6 0,000 0,01093415 0,0582142 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01093415 0,05807976 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01093415 0,05794593 ! response to copper ion GO:0046688 9 6 0,000 0,01093415 0,05781272 ! DNA topological change GO:0006265 8 6 0,000 0,01093415 0,05768013 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01093415 0,05754814 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01093415 0,05741675 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01093415 0,05728596 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01093415 0,05715576 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01093415 0,05702616 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01093415 0,05689714 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01093415 0,0567687 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01093415 0,05664084 ! gas homeostasis GO:0033483 11 6 0,000 0,01093415 0,05651356 ! hair follicle maturation GO:0048820 7 6 0,000 0,01093415 0,05638685 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01093415 0,05626071 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01093415 0,05613512 ! Schwann cell development GO:0014044 14 6 0,000 0,01093415 0,0560101 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01093415 0,05588563 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01093415 0,05576172 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01093415 0,05563835 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01093415 0,05551553 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01093415 0,05539325 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01093415 0,05527151 ! histone ubiquitination GO:0016574 7 6 0,000 0,01093415 0,0551503 ! regulation of meiosis GO:0040020 10 6 0,000 0,01093415 0,05502962 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01093415 0,05490947 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01093415 0,05478984 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01093415 0,05467073 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01093415 0,05455214 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01093415 0,05443406 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01093415 0,05431649 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01093415 0,05419943 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01093415 0,05408287 ! receptor internalization GO:0031623 9 6 0,000 0,01093415 0,05396681 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01093415 0,05385125 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01093415 0,05373619 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01093415 0,05362161 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01093415 0,05350752 ! protein deubiquitination GO:0016579 8 6 0,000 0,01093415 0,05339392 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01093415 0,05328079 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01093415 0,05316815 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01093415 0,05305598 ! axonal fasciculation GO:0007413 9 6 0,000 0,01093415 0,05294428 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01093415 0,05283306 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01093415 0,0527223 ! midbrain development GO:0030901 6 6 0,000 0,01093415 0,052612 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01093415 0,05250216 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01093415 0,05239278 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01093415 0,05228386 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01093415 0,05217538 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01093415 0,05206736 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01093415 0,05195978 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01093415 0,05185265 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01093415 0,05174596 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01093415 0,0516397 ! adult feeding behavior GO:0008343 6 6 0,000 0,01093415 0,05153388 ! pigment granule transport GO:0051904 12 6 0,000 0,01093415 0,0514285 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01093415 0,05132354 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01093415 0,05121901 ! catecholamine transport GO:0051937 7 6 0,000 0,01093415 0,05111491 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01093415 0,05101123 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01093415 0,05090797 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01093415 0,05080512 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01093415 0,05070269 ! protein prenylation GO:0018342 10 6 0,000 0,01093415 0,05060067 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01093415 0,05049907 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01093415 0,05039787 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01093415 0,05029707 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01093415 0,05019668 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01093415 0,05009668 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,01151148 0,052637 ! cell fate commitment GO:0045165 141 92 1,000 0,01226337 0,05596378 ! DNA recombination GO:0006310 146 92 1,000 0,01226337 0,05585296 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,01274521 0,05793276 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01274521 0,05781849 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01274521 0,05770468 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01274521 0,05759131 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01274521 0,05747838 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01274521 0,0573659 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01274521 0,05725386 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01274521 0,05714225 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01274521 0,05703108 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01274521 0,05692034 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01274521 0,05681003 ! reproductive behavior GO:0019098 12 7 0,000 0,01274521 0,05670015 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01274521 0,05659069 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01274521 0,05648165 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01274521 0,05637303 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01274521 0,05626483 ! oligopeptide transport GO:0006857 11 7 0,000 0,01274521 0,05615704 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01274521 0,05604967 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01274521 0,0559427 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01274521 0,05583615 ! RNA methylation GO:0001510 11 7 0,000 0,01274521 0,05572999 ! pericardium development GO:0060039 8 7 0,000 0,01274521 0,05562424 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01274521 0,05551889 ! fibril organization GO:0043206 13 7 0,000 0,01274521 0,05541394 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01274521 0,05530939 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01274521 0,05520523 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01274521 0,05510146 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01274521 0,05499808 ! lipoprotein transport GO:0042953 9 7 0,000 0,01274521 0,05489509 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01274521 0,05479248 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01274521 0,05469025 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01274521 0,05458841 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01274521 0,05448694 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01274521 0,05438586 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01274521 0,05428514 ! chemosensory behavior GO:0007635 9 7 0,000 0,01274521 0,0541848 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01274521 0,05408483 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01274521 0,05398522 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01274521 0,05388599 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01274521 0,05378711 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01274521 0,0536886 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01274521 0,05359045 ! reflex GO:0060004 12 7 0,000 0,01274521 0,05349266 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01274521 0,05339522 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01274521 0,05329814 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01274521 0,05320141 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01274521 0,05310503 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01274521 0,053009 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01274521 0,05291331 ! spinal cord patterning GO:0021511 7 7 0,000 0,01274521 0,05281798 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01274521 0,05272298 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01274521 0,05262832 ! adrenal gland development GO:0030325 17 7 0,000 0,01274521 0,05253401 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01274521 0,05244003 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01274521 0,05234639 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01274521 0,05225308 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01274521 0,0521601 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01274521 0,05206745 ! endosome organization GO:0007032 10 7 0,000 0,01274521 0,05197514 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01274521 0,05188314 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01274521 0,05179148 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01274521 0,05170013 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01274521 0,05160911 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01274521 0,05151841 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01274521 0,05142803 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01274521 0,05133796 ! galactose metabolic process GO:0006012 10 7 0,000 0,01274521 0,05124821 ! vesicle fusion GO:0006906 15 7 0,000 0,01274521 0,05115877 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01274521 0,05106964 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01274521 0,05098083 ! organ growth GO:0035265 11 7 0,000 0,01274521 0,05089232 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01274521 0,05080412 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01274521 0,05071622 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01274521 0,05062863 ! retinol metabolic process GO:0042572 9 7 0,000 0,01274521 0,05054134 ! behavioral fear response GO:0001662 13 7 0,000 0,01274521 0,05045435 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01274521 0,05036766 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01274521 0,05028126 ! rRNA modification GO:0000154 12 7 0,000 0,01274521 0,05019516 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01274521 0,05010936 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01274521 0,05002385 ! response to UV-B GO:0010224 11 7 0,000 0,01274521 0,04993863 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01274521 0,0498537 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01274521 0,04976906 ! intermediate filament organization GO:0045109 11 7 0,000 0,01274521 0,04968471 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01274521 0,04960064 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01274521 0,04951685 ! fibrinolysis GO:0042730 9 7 0,000 0,01274521 0,04943335 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01274521 0,04935013 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01274521 0,04926719 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01274521 0,04918452 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01274521 0,04910214 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01274521 0,04902003 ! response to tropane GO:0014073 13 7 0,000 0,01274521 0,04893819 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01274521 0,04885663 ! melanosome localization GO:0032400 10 7 0,000 0,01274521 0,04877533 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01274521 0,04869431 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01274521 0,04861356 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01274521 0,04853307 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01274521 0,04845285 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01274521 0,0483729 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01274521 0,04829321 ! mast cell activation GO:0045576 9 7 0,000 0,01274521 0,04821378 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01274521 0,04813461 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01274521 0,0480557 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01274521 0,04797705 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01274521 0,04789865 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01274521 0,04782052 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01274521 0,04774263 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01274521 0,047665 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01274521 0,04758762 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01274521 0,0475105 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01274521 0,04743362 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01274521 0,04735699 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01274521 0,04728061 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01274521 0,04720447 ! response to tumor cell GO:0002347 12 7 0,000 0,01274521 0,04712858 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01274521 0,04705293 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01274521 0,04697753 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01274521 0,04690236 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01274521 0,04682744 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01274521 0,04675275 ! diuresis GO:0030146 12 7 0,000 0,01274521 0,04667831 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01274521 0,0466041 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01274521 0,04653012 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01274521 0,04645638 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01274521 0,04638287 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01274521 0,0463096 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01274521 0,04623656 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01274521 0,04616374 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01274521 0,04609116 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01274521 0,0460188 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01274521 0,04594667 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01274521 0,04587477 ! lymph node development GO:0048535 9 7 0,000 0,01274521 0,04580309 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01274521 0,04573163 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01274521 0,0456604 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01274521 0,04558939 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01274521 0,0455186 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01274521 0,04544803 ! ATP catabolic process GO:0006200 10 7 0,000 0,01274521 0,04537767 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01274521 0,04530754 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01274521 0,04523762 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01274521 0,04516791 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01274521 0,04509842 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01274521 0,04502915 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01274521 0,04496009 ! muscle adaptation GO:0043500 12 7 0,000 0,01274521 0,04489123 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01274521 0,04482259 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01274521 0,04475416 ! retina homeostasis GO:0001895 9 7 0,000 0,01274521 0,04468594 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01274521 0,04461792 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01274521 0,04455012 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01274521 0,04448251 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01274521 0,04441512 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01274521 0,04434792 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01274521 0,04428093 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01274521 0,04421414 ! in utero embryonic development GO:0001701 147 96 1,000 0,01329858 0,04606437 ! response to light stimulus GO:0009416 153 96 1,000 0,01329858 0,0459951 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01455306 0,0502583 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01455306 0,05018295 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01455306 0,05010783 ! axon extension GO:0048675 11 8 0,000 0,01455306 0,05003293 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01455306 0,04995825 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01455306 0,0498838 ! associative learning GO:0008306 15 8 0,000 0,01455306 0,04980957 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01455306 0,04973555 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01455306 0,04966176 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01455306 0,04958819 ! phosphate transport GO:0006817 10 8 0,000 0,01455306 0,04951483 ! N-glycan processing GO:0006491 12 8 0,000 0,01455306 0,0494417 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01455306 0,04936877 ! UTP metabolic process GO:0046051 8 8 0,000 0,01455306 0,04929606 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01455306 0,04922357 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01455306 0,04915129 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01455306 0,04907922 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01455306 0,04900736 ! succinate metabolic process GO:0006105 14 8 0,000 0,01455306 0,04893571 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01455306 0,04886427 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01455306 0,04879304 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01455306 0,04872202 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01455306 0,0486512 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01455306 0,04858059 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01455306 0,04851019 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01455306 0,04843998 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01455306 0,04836998 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01455306 0,04830018 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01455306 0,04823059 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01455306 0,04816119 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01455306 0,04809199 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01455306 0,048023 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01455306 0,04795419 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01455306 0,04788559 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01455306 0,04781718 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01455306 0,04774897 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01455306 0,04768095 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01455306 0,04761313 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01455306 0,04754549 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01455306 0,04747805 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01455306 0,0474108 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01455306 0,04734375 ! melanin metabolic process GO:0006582 12 8 0,000 0,01455306 0,04727688 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01455306 0,04721019 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01455306 0,0471437 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01455306 0,04707739 ! macrophage activation GO:0042116 12 8 0,000 0,01455306 0,04701128 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01455306 0,04694534 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01455306 0,04687959 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01455306 0,04681402 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01455306 0,04674864 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01455306 0,04668344 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01455306 0,04661842 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01455306 0,04655359 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01455306 0,04648893 ! ruffle organization GO:0031529 11 8 0,000 0,01455306 0,04642445 ! osteoblast development GO:0002076 13 8 0,000 0,01455306 0,04636015 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01455306 0,04629603 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01455306 0,04623208 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01455306 0,04616831 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01455306 0,04610472 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01455306 0,0460413 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01455306 0,04597806 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01455306 0,04591499 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01455306 0,04585209 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01455306 0,04578937 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01455306 0,04572681 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01455306 0,04566443 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01455306 0,04560222 ! segment specification GO:0007379 10 8 0,000 0,01455306 0,04554017 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01455306 0,0454783 ! cellular extravasation GO:0045123 11 8 0,000 0,01455306 0,04541659 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01455306 0,04535505 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01455306 0,04529368 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01455306 0,04523247 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01455306 0,04517143 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01455306 0,04511055 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01455306 0,04504984 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01455306 0,04498928 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01455306 0,0449289 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01455306 0,04486867 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01455306 0,0448086 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01455306 0,0447487 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01455306 0,04468896 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01455306 0,04462937 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01455306 0,04456994 ! icosanoid secretion GO:0032309 12 8 0,000 0,01455306 0,04451068 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01455306 0,04445156 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01455306 0,04439261 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01455306 0,04433381 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01455306 0,04427517 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01455306 0,04421668 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01455306 0,04415835 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01455306 0,04410017 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01455306 0,04404214 ! sterol catabolic process GO:0016127 9 8 0,000 0,01455306 0,04398427 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01455306 0,04392655 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01455306 0,04386897 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01455306 0,04381155 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01455306 0,04375428 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01455306 0,04369716 ! prophase GO:0051324 11 8 0,000 0,01455306 0,04364019 ! S phase GO:0051320 8 8 0,000 0,01455306 0,04358337 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01455306 0,04352669 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01455306 0,04347017 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01455306 0,04341378 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01455306 0,04335755 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01455306 0,04330146 ! hormone catabolic process GO:0042447 13 8 0,000 0,01455306 0,04324551 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01455306 0,04318971 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01455306 0,04313406 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01455306 0,04307854 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01455306 0,04302317 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01455306 0,04296794 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01455306 0,04291286 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01455306 0,04285791 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01455306 0,0428031 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01455306 0,04274844 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01455306 0,04269391 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01455306 0,04263953 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01455306 0,04258528 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01455306 0,04253117 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01455306 0,04247719 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01455306 0,04242336 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,0163577 0,04762367 ! regulation of developmental growth GO:0048638 13 9 0,000 0,0163577 0,04756347 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,0163577 0,04750341 ! telencephalon cell migration GO:0022029 16 9 0,000 0,0163577 0,04744351 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,0163577 0,04738376 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,0163577 0,04732415 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,0163577 0,0472647 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,0163577 0,0472054 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0163577 0,04714624 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,0163577 0,04708724 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,0163577 0,04702838 ! GTP metabolic process GO:0046039 9 9 0,000 0,0163577 0,04696967 ! elastic fiber assembly GO:0048251 13 9 0,000 0,0163577 0,0469111 ! social behavior GO:0035176 14 9 0,000 0,0163577 0,04685268 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,0163577 0,04679441 ! artery development GO:0060840 19 9 0,000 0,0163577 0,04673628 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,0163577 0,04667829 ! regulation of glycolysis GO:0006110 15 9 0,000 0,0163577 0,04662045 ! response to pain GO:0048265 16 9 0,000 0,0163577 0,04656275 ! protein complex disassembly GO:0043241 17 9 0,000 0,0163577 0,0465052 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,0163577 0,04644778 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,0163577 0,04639051 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,0163577 0,04633338 ! lung alveolus development GO:0048286 17 9 0,000 0,0163577 0,04627639 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,0163577 0,04621954 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,0163577 0,04616283 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,0163577 0,04610625 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,0163577 0,04604982 ! ventral spinal cord development GO:0021517 11 9 0,000 0,0163577 0,04599352 ! protein targeting to ER GO:0045047 19 9 0,000 0,0163577 0,04593737 ! T cell selection GO:0045058 18 9 0,000 0,0163577 0,04588134 ! endoderm development GO:0007492 12 9 0,000 0,0163577 0,04582546 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,0163577 0,04576971 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,0163577 0,0457141 ! arginine catabolic process GO:0006527 10 9 0,000 0,0163577 0,04565862 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,0163577 0,04560328 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,0163577 0,04554807 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,0163577 0,04549299 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0163577 0,04543805 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,0163577 0,04538324 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,0163577 0,04532856 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,0163577 0,04527401 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,0163577 0,04521959 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0163577 0,04516531 ! mannose metabolic process GO:0006013 9 9 0,000 0,0163577 0,04511115 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,0163577 0,04505713 ! receptor clustering GO:0043113 15 9 0,000 0,0163577 0,04500323 ! epithelial cell development GO:0002064 10 9 0,000 0,0163577 0,04494947 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,0163577 0,04489583 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,0163577 0,04484232 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,0163577 0,04478893 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,0163577 0,04473568 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,0163577 0,04468254 ! motor axon guidance GO:0008045 14 9 0,000 0,0163577 0,04462954 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,0163577 0,04457666 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,0163577 0,04452391 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,0163577 0,04447128 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,0163577 0,04441878 ! blastoderm segmentation GO:0007350 11 9 0,000 0,0163577 0,04436639 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,0163577 0,04431414 ! DNA ligation GO:0006266 14 9 0,000 0,0163577 0,044262 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,0163577 0,04420999 ! response to amine stimulus GO:0014075 13 9 0,000 0,0163577 0,0441581 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,0163577 0,04410633 ! erythrocyte development GO:0048821 11 9 0,000 0,0163577 0,04405469 ! renal water homeostasis GO:0003091 14 9 0,000 0,0163577 0,04400316 ! postreplication repair GO:0006301 11 9 0,000 0,0163577 0,04395176 ! mRNA cleavage GO:0006379 13 9 0,000 0,0163577 0,04390047 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,0163577 0,0438493 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,0163577 0,04379826 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,0163577 0,04374733 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,0163577 0,04369652 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,0163577 0,04364583 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,0163577 0,04359525 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,0163577 0,04354479 ! acid secretion GO:0046717 14 9 0,000 0,0163577 0,04349445 ! musculoskeletal movement GO:0050881 11 9 0,000 0,0163577 0,04344423 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,0163577 0,04339412 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,0163577 0,04334413 ! purine base metabolic process GO:0006144 18 9 0,000 0,0163577 0,04329425 ! oocyte differentiation GO:0009994 12 9 0,000 0,0163577 0,04324449 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,0163577 0,04319484 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,0163577 0,0431453 ! spleen development GO:0048536 15 9 0,000 0,0163577 0,04309588 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,0163577 0,04304657 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,0163577 0,04299737 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,0163577 0,04294829 ! detection of calcium ion GO:0005513 13 9 0,000 0,0163577 0,04289932 ! blastocyst formation GO:0001825 12 9 0,000 0,0163577 0,04285046 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,0163577 0,04280171 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,0163577 0,04275307 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,0163577 0,04270454 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,0163577 0,04265613 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0163577 0,04260782 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,0163577 0,04255962 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,0163577 0,04251153 ! prepulse inhibition GO:0060134 14 9 0,000 0,0163577 0,04246355 ! embryonic placenta development GO:0001892 12 9 0,000 0,0163577 0,04241567 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,0163577 0,04236791 ! insulin secretion GO:0030073 17 9 0,000 0,0163577 0,04232025 ! sequestering of metal ion GO:0051238 11 9 0,000 0,0163577 0,0422727 ! response to nicotine GO:0035094 16 9 0,000 0,0163577 0,04222526 ! establishment of cell polarity GO:0030010 12 9 0,000 0,0163577 0,04217792 ! nucleus localization GO:0051647 15 9 0,000 0,0163577 0,04213069 ! regulation of synapse organization GO:0050807 12 9 0,000 0,0163577 0,04208356 ! localization within membrane GO:0051668 15 9 0,000 0,0163577 0,04203654 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01815914 0,04661385 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01815914 0,04656189 ! neuron fate specification GO:0048665 11 10 0,000 0,01815914 0,04651004 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01815914 0,0464583 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01815914 0,04640668 ! thyroid gland development GO:0030878 19 10 0,000 0,01815914 0,04635518 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01815914 0,04630378 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01815914 0,04625251 ! synapsis GO:0007129 13 10 0,000 0,01815914 0,04620134 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01815914 0,04615029 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01815914 0,04609935 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01815914 0,04604853 ! sulfate transport GO:0008272 12 10 0,000 0,01815914 0,04599781 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01815914 0,04594721 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01815914 0,04589672 ! androgen metabolic process GO:0008209 13 10 0,000 0,01815914 0,04584634 ! phospholipid efflux GO:0033700 16 10 0,000 0,01815914 0,04579607 ! hippocampus development GO:0021766 19 10 0,000 0,01815914 0,04574591 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01815914 0,04569586 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01815914 0,04564592 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01815914 0,04559608 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01815914 0,04554636 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01815914 0,04549675 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01815914 0,04544724 ! pathogenesis GO:0009405 13 10 0,000 0,01815914 0,04539784 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01815914 0,04534855 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01815914 0,04529936 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01815914 0,04525029 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01815914 0,04520131 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01815914 0,04515245 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01815914 0,04510369 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01815914 0,04505503 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01815914 0,04500648 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01815914 0,04495803 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01815914 0,04490969 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01815914 0,04486145 ! response to X-ray GO:0010165 16 10 0,000 0,01815914 0,04481332 ! B cell proliferation GO:0042100 14 10 0,000 0,01815914 0,04476529 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01815914 0,04471736 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01815914 0,04466953 ! forebrain cell migration GO:0021885 17 10 0,000 0,01815914 0,04462181 ! lipid digestion GO:0044241 15 10 0,000 0,01815914 0,04457419 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01815914 0,04452667 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01815914 0,04447925 ! UV protection GO:0009650 14 10 0,000 0,01815914 0,04443193 ! entry into host cell GO:0030260 20 10 0,000 0,01815914 0,04438471 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01815914 0,04433759 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01815914 0,04429058 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01815914 0,04424366 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01815914 0,04419684 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01815914 0,04415012 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01815914 0,0441035 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01815914 0,04405698 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01815914 0,04401055 ! regulation of organ growth GO:0046620 11 10 0,000 0,01815914 0,04396423 ! response to dsRNA GO:0043331 18 10 0,000 0,01815914 0,043918 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01815914 0,04387186 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01815914 0,04382583 ! embryonic axis specification GO:0000578 12 10 0,000 0,01815914 0,04377989 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01815914 0,04373405 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01815914 0,0436883 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01815914 0,04364265 ! cranial nerve development GO:0021545 12 10 0,000 0,01815914 0,04359709 ! fucose catabolic process GO:0019317 16 10 0,000 0,01815914 0,04355163 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01815914 0,04350626 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01815914 0,04346099 ! protein sumoylation GO:0016925 12 10 0,000 0,01815914 0,04341581 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01815914 0,04337073 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01815914 0,04332574 ! zymogen activation GO:0031638 14 10 0,000 0,01815914 0,04328084 ! salivary gland development GO:0007431 22 10 0,000 0,01815914 0,04323604 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01815914 0,04319133 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01815914 0,04314671 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01815914 0,04310218 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01815914 0,04305775 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01815914 0,0430134 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01815914 0,04296915 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01815914 0,04292499 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01815914 0,04288092 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01815914 0,04283694 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01815914 0,04279305 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01815914 0,04274925 ! detection of bacterium GO:0016045 10 10 0,000 0,01815914 0,04270554 ! embryonic gut development GO:0048566 11 10 0,000 0,01815914 0,04266191 ! activation of innate immune response GO:0002218 10 10 0,000 0,01815914 0,04261838 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01815914 0,04257494 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01815914 0,04253158 ! developmental induction GO:0031128 13 10 0,000 0,01815914 0,04248832 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01815914 0,04244514 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01815914 0,04240204 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01815914 0,04235904 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01815914 0,04231612 ! rRNA transcription GO:0009303 17 11 0,000 0,01995738 0,04645949 ! respiratory burst GO:0045730 14 11 0,000 0,01995738 0,04641251 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01995738 0,04636563 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01995738 0,04631884 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01995738 0,04627215 ! virus-host interaction GO:0019048 17 11 0,000 0,01995738 0,04622555 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01995738 0,04617905 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01995738 0,04613264 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01995738 0,04608632 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01995738 0,04604009 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01995738 0,04599396 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01995738 0,04594792 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01995738 0,04590197 ! mating GO:0007618 14 11 0,000 0,01995738 0,04585612 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01995738 0,04581035 ! T cell proliferation GO:0042098 20 11 0,000 0,01995738 0,04576468 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01995738 0,0457191 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01995738 0,04567361 ! bone resorption GO:0045453 16 11 0,000 0,01995738 0,0456282 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01995738 0,04558289 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01995738 0,04553767 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01995738 0,04549254 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01995738 0,0454475 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01995738 0,04540255 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01995738 0,04535768 ! syncytium formation GO:0006949 15 11 0,000 0,01995738 0,04531291 ! plasma membrane organization GO:0007009 18 11 0,000 0,01995738 0,04526822 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01995738 0,04522362 ! focal adhesion formation GO:0048041 24 11 0,000 0,01995738 0,04517911 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01995738 0,04513468 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01995738 0,04509035 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01995738 0,0450461 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01995738 0,04500193 ! adult heart development GO:0007512 11 11 0,000 0,01995738 0,04495786 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01995738 0,04491387 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01995738 0,04486996 ! temperature homeostasis GO:0001659 16 11 0,000 0,01995738 0,04482615 ! L-glutamate transport GO:0015813 16 11 0,000 0,01995738 0,04478241 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01995738 0,04473877 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01995738 0,0446952 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01995738 0,04465173 ! stem cell development GO:0048864 29 11 0,000 0,01995738 0,04460833 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01995738 0,04456502 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01995738 0,0445218 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01995738 0,04447866 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01995738 0,0444356 ! vasoconstriction GO:0042310 15 11 0,000 0,01995738 0,04439262 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01995738 0,04434973 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01995738 0,04430692 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01995738 0,0442642 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01995738 0,04422155 ! ribosome assembly GO:0042255 13 11 0,000 0,01995738 0,04417899 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01995738 0,04413651 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01995738 0,04409411 ! nucleosome positioning GO:0016584 13 11 0,000 0,01995738 0,0440518 ! T cell homeostasis GO:0043029 20 11 0,000 0,01995738 0,04400956 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01995738 0,04396741 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01995738 0,04392533 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01995738 0,04388334 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01995738 0,04384143 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01995738 0,04379959 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01995738 0,04375784 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01995738 0,04371617 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01995738 0,04367457 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01995738 0,04363305 ! male genitalia development GO:0030539 13 11 0,000 0,01995738 0,04359162 ! cholesterol efflux GO:0033344 19 11 0,000 0,01995738 0,04355026 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01995738 0,04350898 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01995738 0,04346778 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01995738 0,04342665 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01995738 0,04338561 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01995738 0,04334464 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01995738 0,04330375 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01995738 0,04326293 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01995738 0,0432222 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01995738 0,04318154 ! lysogeny GO:0030069 18 11 0,000 0,01995738 0,04314095 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01995738 0,04310044 ! acrosome reaction GO:0007340 13 11 0,000 0,01995738 0,04306001 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01995738 0,04301966 ! lactation GO:0007595 20 12 0,000 0,02175243 0,04684513 ! reproductive cellular process GO:0048610 14 12 0,000 0,02175243 0,0468013 ! tRNA modification GO:0006400 14 12 0,000 0,02175243 0,04675756 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02175243 0,04671391 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02175243 0,04667033 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02175243 0,04662684 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02175243 0,04658342 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02175243 0,04654009 ! non-recombinational repair GO:0000726 19 12 0,000 0,02175243 0,04649684 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02175243 0,04645366 ! peroxisomal transport GO:0043574 21 12 0,000 0,02175243 0,04641057 ! cartilage condensation GO:0001502 18 12 0,000 0,02175243 0,04636756 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02175243 0,04632462 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02175243 0,04628177 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02175243 0,046239 ! heart looping GO:0001947 15 12 0,000 0,02175243 0,0461963 ! palate development GO:0060021 15 12 0,000 0,02175243 0,04615368 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02175243 0,04611115 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02175243 0,04606869 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02175243 0,04602631 ! arginine metabolic process GO:0006525 13 12 0,000 0,02175243 0,045984 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02175243 0,04594178 ! methionine metabolic process GO:0006555 13 12 0,000 0,02175243 0,04589963 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02175243 0,04585756 ! Golgi organization GO:0007030 18 12 0,000 0,02175243 0,04581556 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02175243 0,04577365 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02175243 0,0457318 ! monoamine transport GO:0015844 13 12 0,000 0,02175243 0,04569004 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02175243 0,04564835 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02175243 0,04560674 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02175243 0,0455652 ! L-amino acid transport GO:0015807 20 12 0,000 0,02175243 0,04552374 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02175243 0,04548236 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02175243 0,04544105 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02175243 0,04539981 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02175243 0,04535865 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02175243 0,04531757 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02175243 0,04527656 ! cerebellum development GO:0021549 13 12 0,000 0,02175243 0,04523562 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02175243 0,04519476 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02175243 0,04515397 ! histone acetylation GO:0016573 23 12 0,000 0,02175243 0,04511325 ! histone methylation GO:0016571 15 12 0,000 0,02175243 0,04507261 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02175243 0,04503204 ! gland morphogenesis GO:0022612 23 12 0,000 0,02175243 0,04499154 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02175243 0,04495112 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,02175243 0,04491077 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02175243 0,04487049 ! response to gamma radiation GO:0010332 20 12 0,000 0,02175243 0,04483028 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02175243 0,04479015 ! intestinal absorption GO:0050892 19 12 0,000 0,02175243 0,04475008 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02175243 0,04471009 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02175243 0,04467017 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02175243 0,04463033 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02175243 0,04459055 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02175243 0,04455084 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02175243 0,04451121 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02175243 0,04447164 ! microspike assembly GO:0030035 23 12 0,000 0,02175243 0,04443214 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02175243 0,04439272 ! response to cold GO:0009409 14 12 0,000 0,02175243 0,04435336 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,0235443 0,04796447 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,0235443 0,04792203 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,0235443 0,04787965 ! cGMP metabolic process GO:0046068 16 13 0,000 0,0235443 0,04783736 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,0235443 0,04779514 ! water transport GO:0006833 17 13 0,000 0,0235443 0,04775299 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,0235443 0,04771092 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,0235443 0,04766892 ! lipid localization GO:0010876 24 13 0,000 0,0235443 0,04762699 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,0235443 0,04758514 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,0235443 0,04754336 ! organelle fusion GO:0048284 28 13 0,000 0,0235443 0,04750166 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,0235443 0,04746003 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,0235443 0,04741847 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,0235443 0,04737698 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,0235443 0,04733557 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,0235443 0,04729423 ! response to hexose stimulus GO:0009746 19 13 0,000 0,0235443 0,04725296 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,0235443 0,04721176 ! glutamate metabolic process GO:0006536 18 13 0,000 0,0235443 0,04717064 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,0235443 0,04712958 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,0235443 0,0470886 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,0235443 0,04704769 ! NAD metabolic process GO:0019674 21 13 0,000 0,0235443 0,04700685 ! exocrine system development GO:0035272 27 13 0,000 0,0235443 0,04696608 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,0235443 0,04692538 ! bone mineralization GO:0030282 15 13 0,000 0,0235443 0,04688475 ! regulation of exocytosis GO:0017157 17 13 0,000 0,0235443 0,04684419 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,0235443 0,04680371 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,0235443 0,04676329 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,0235443 0,04672294 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,0235443 0,04668266 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,0235443 0,04664245 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,0235443 0,04660231 ! genitalia development GO:0048806 15 13 0,000 0,0235443 0,04656224 ! regulation of cellular pH GO:0030641 20 13 0,000 0,0235443 0,04652224 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,0235443 0,04648231 ! cellular pigmentation GO:0033059 24 13 0,000 0,0235443 0,04644244 ! tissue regeneration GO:0042246 21 13 0,000 0,0235443 0,04640265 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,0235443 0,04636292 ! cofactor transport GO:0051181 19 13 0,000 0,0235443 0,04632326 ! NADP metabolic process GO:0006739 18 13 0,000 0,0235443 0,04628367 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,0235443 0,04624414 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,0235443 0,04620468 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0235443 0,04616529 ! gas transport GO:0015669 18 13 0,000 0,0235443 0,04612597 ! regulation of RNA stability GO:0043487 28 13 0,000 0,0235443 0,04608671 ! heme biosynthetic process GO:0006783 20 13 0,000 0,0235443 0,04604752 ! regulation of axon extension GO:0030516 23 13 0,000 0,0235443 0,0460084 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,0235443 0,04596935 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,0235443 0,04593036 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,0235443 0,04589143 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,0235443 0,04585257 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,0235443 0,04581378 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,0235443 0,04577505 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02533299 0,04921104 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02533299 0,04916951 ! superoxide anion generation GO:0042554 18 14 0,000 0,02533299 0,04912805 ! neuron maturation GO:0042551 21 14 0,000 0,02533299 0,04908666 ! regulation of S phase GO:0033261 18 14 0,000 0,02533299 0,04904535 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,02533299 0,0490041 ! myotube differentiation GO:0014902 21 14 0,000 0,02533299 0,04896292 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02533299 0,04892181 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02533299 0,04888076 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,02533299 0,04883979 ! inositol metabolic process GO:0006020 20 14 0,000 0,02533299 0,04879889 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02533299 0,04875805 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02533299 0,04871728 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02533299 0,04867658 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02533299 0,04863595 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02533299 0,04859539 ! response to cAMP GO:0051591 19 14 0,000 0,02533299 0,04855489 ! limbic system development GO:0021761 25 14 0,000 0,02533299 0,04851446 ! startle response GO:0001964 21 14 0,000 0,02533299 0,0484741 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,02533299 0,04843381 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02533299 0,04839358 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02533299 0,04835342 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02533299 0,04831333 ! glycine metabolic process GO:0006544 22 14 0,000 0,02533299 0,0482733 ! pituitary gland development GO:0021983 23 14 0,000 0,02533299 0,04823334 ! cellular response to starvation GO:0009267 21 14 0,000 0,02533299 0,04819344 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,02533299 0,04815361 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,02533299 0,04811385 ! regulation of heart rate GO:0002027 23 14 0,000 0,02533299 0,04807415 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02533299 0,04803452 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02533299 0,04799495 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02533299 0,04795545 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02533299 0,04791601 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02533299 0,04787664 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02533299 0,04783733 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02533299 0,04779809 ! axon cargo transport GO:0008088 27 14 0,000 0,02533299 0,04775891 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02533299 0,0477198 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02533299 0,04768075 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02533299 0,04764176 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02533299 0,04760284 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02533299 0,04756398 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02533299 0,04752518 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02533299 0,04748645 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02533299 0,04744778 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02533299 0,04740917 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02533299 0,04737063 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02533299 0,04733215 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02533299 0,04729373 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,02533299 0,04725537 ! muscle maintenance GO:0046716 19 14 0,000 0,02533299 0,04721708 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02533299 0,04717884 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02533299 0,04714067 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02533299 0,04710256 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02533299 0,04706452 ! cell killing GO:0001906 20 14 0,000 0,02533299 0,04702653 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02533299 0,04698861 ! cilium assembly GO:0042384 20 14 0,000 0,02533299 0,04695074 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02533299 0,04691294 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,0271185 0,05017904 ! metencephalon development GO:0022037 19 15 0,000 0,0271185 0,05013871 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,0271185 0,05009843 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,0271185 0,05005823 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,0271185 0,05001808 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,0271185 0,04997801 ! lipid phosphorylation GO:0046834 23 15 0,000 0,0271185 0,04993799 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,0271185 0,04989804 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,0271185 0,04985815 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,0271185 0,04981833 ! bile acid metabolic process GO:0008206 22 15 0,000 0,0271185 0,04977857 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,0271185 0,04973888 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,0271185 0,04969924 ! adult walking behavior GO:0007628 25 15 0,000 0,0271185 0,04965967 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,0271185 0,04962017 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,0271185 0,04958072 ! myoblast differentiation GO:0045445 27 15 0,000 0,0271185 0,04954134 ! centrosome cycle GO:0007098 16 15 0,000 0,0271185 0,04950202 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,0271185 0,04946277 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,0271185 0,04942357 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,0271185 0,04938444 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,0271185 0,04934537 ! cerebral cortex development GO:0021987 29 15 0,000 0,0271185 0,04930636 ! response to osmotic stress GO:0006970 22 15 0,000 0,0271185 0,04926742 ! vesicle coating GO:0006901 25 15 0,000 0,0271185 0,04922853 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,0271185 0,04918971 ! DNA integration GO:0015074 22 15 0,000 0,0271185 0,04915095 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,0271185 0,04911224 ! peptide secretion GO:0002790 27 15 0,000 0,0271185 0,0490736 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,0271185 0,04903502 ! regulation of vasodilation GO:0042312 24 15 0,000 0,0271185 0,04899651 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,0271185 0,04895805 ! neuron recognition GO:0008038 22 15 0,000 0,0271185 0,04891965 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,0271185 0,04888131 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,0271185 0,04884303 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,0271185 0,04880481 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,0271185 0,04876665 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,0271185 0,04872856 ! biomineral formation GO:0031214 18 15 0,000 0,0271185 0,04869052 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,0271185 0,04865254 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,0271185 0,04861461 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,0271185 0,04857675 ! dopamine metabolic process GO:0042417 30 15 0,000 0,0271185 0,04853895 ! organic cation transport GO:0015695 19 15 0,000 0,0271185 0,04850121 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,0271185 0,04846352 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,0271185 0,04842589 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,0271185 0,04838833 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,0271185 0,04835081 ! defense response to virus GO:0051607 27 15 0,000 0,0271185 0,04831336 ! peptide hormone processing GO:0016486 19 15 0,000 0,0271185 0,04827597 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,0271185 0,04823863 ! protein secretion GO:0009306 27 16 0,000 0,02890084 0,05136935 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02890084 0,05132969 ! hormone secretion GO:0046879 25 16 0,000 0,02890084 0,05129008 ! bone remodeling GO:0046849 24 16 0,000 0,02890084 0,05125053 ! endothelial cell migration GO:0043542 22 16 0,000 0,02890084 0,05121105 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02890084 0,05117163 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02890084 0,05113226 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02890084 0,05109296 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02890084 0,05105372 ! glial cell development GO:0021782 24 16 0,000 0,02890084 0,05101454 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02890084 0,05097542 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02890084 0,05093635 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02890084 0,05089735 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02890084 0,05085841 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02890084 0,05081953 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,02890084 0,05078071 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02890084 0,05074194 ! regulation of protein binding GO:0043393 27 16 0,000 0,02890084 0,05070324 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02890084 0,05066459 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02890084 0,050626 ! protein export from nucleus GO:0006611 24 16 0,000 0,02890084 0,05058748 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02890084 0,05054901 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02890084 0,05051059 ! DNA replication initiation GO:0006270 25 16 0,000 0,02890084 0,05047224 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02890084 0,05043395 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02890084 0,05039571 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02890084 0,05035753 ! diencephalon development GO:0021536 25 16 0,000 0,02890084 0,05031941 ! oogenesis GO:0048477 23 16 0,000 0,02890084 0,05028135 ! neural crest cell migration GO:0001755 24 16 0,000 0,02890084 0,05024334 ! G1 phase GO:0051318 27 16 0,000 0,02890084 0,05020539 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02890084 0,0501675 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02890084 0,05012967 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02890084 0,05009189 ! steroid catabolic process GO:0006706 22 16 0,000 0,02890084 0,05005417 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02890084 0,05001651 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02890084 0,0499789 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02890084 0,04994135 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02890084 0,04990386 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02890084 0,04986642 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02890084 0,04982904 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02890084 0,04979172 ! nerve development GO:0021675 18 16 0,000 0,02890084 0,04975445 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02890084 0,04971723 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02890084 0,04968008 ! negative regulation of translation GO:0017148 22 16 0,000 0,02890084 0,04964297 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,03068003 0,05265975 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,03068003 0,05262048 ! negative regulation of defense response GO:0031348 19 17 0,000 0,03068003 0,05258127 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,03068003 0,05254211 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,03068003 0,05250302 ! glycerol metabolic process GO:0006071 20 17 0,000 0,03068003 0,05246398 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,03068003 0,05242501 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,03068003 0,05238609 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,03068003 0,05234722 ! signal complex assembly GO:0007172 29 17 0,000 0,03068003 0,05230842 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,03068003 0,05226967 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,03068003 0,05223098 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,03068003 0,05219235 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,03068003 0,05215378 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,03068003 0,05211526 ! memory GO:0007613 25 17 0,000 0,03068003 0,0520768 ! keratinization GO:0031424 17 17 0,000 0,03068003 0,05203839 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,03068003 0,05200004 ! retinoid metabolic process GO:0001523 22 17 0,000 0,03068003 0,05196175 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,03068003 0,05192352 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,03068003 0,05188534 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,03068003 0,05184721 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,03068003 0,05180915 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,03068003 0,05177114 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,03068003 0,05173318 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,03068003 0,05169528 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,03068003 0,05165744 ! membrane budding GO:0006900 29 17 0,000 0,03068003 0,05161965 ! heme metabolic process GO:0042168 27 17 0,000 0,03068003 0,05158191 ! actin filament bundle formation GO:0051017 26 17 0,000 0,03068003 0,05154424 ! neuromuscular junction development GO:0007528 23 17 0,000 0,03068003 0,05150661 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,03068003 0,05146904 ! body fluid secretion GO:0007589 27 17 0,000 0,03068003 0,05143153 ! stem cell differentiation GO:0048863 36 17 0,000 0,03068003 0,05139407 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,03068003 0,05135667 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,03068003 0,05131932 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,03068003 0,05128202 ! sensory perception of pain GO:0019233 23 17 0,000 0,03068003 0,05124478 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,03068003 0,05120759 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,03068003 0,05117046 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,03068003 0,05113338 ! synaptogenesis GO:0007416 24 17 0,000 0,03068003 0,05109635 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,03068003 0,05105938 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,03068003 0,05102246 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,03068003 0,05098559 ! cell-cell junction organization GO:0045216 25 17 0,000 0,03068003 0,05094878 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,03068003 0,05091202 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,03068003 0,05087531 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,03068003 0,05083866 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,03068003 0,05080206 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,03068003 0,05076551 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,03068003 0,05072901 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03245605 0,05362709 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03245605 0,05358859 ! positive regulation of translation GO:0045727 28 18 0,000 0,03245605 0,05355015 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03245605 0,05351176 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03245605 0,05347343 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03245605 0,05343515 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03245605 0,05339693 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03245605 0,05335876 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03245605 0,05332065 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03245605 0,05328259 ! axis specification GO:0009798 26 18 0,000 0,03245605 0,05324459 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03245605 0,05320664 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03245605 0,05316874 ! pancreas development GO:0031016 26 18 0,000 0,03245605 0,0531309 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03245605 0,05309311 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03245605 0,05305537 ! response to retinoic acid GO:0032526 25 18 0,000 0,03245605 0,05301769 ! pigmentation during development GO:0048066 31 18 0,000 0,03245605 0,05298006 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03245605 0,05294249 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,03245605 0,05290497 ! fucose metabolic process GO:0006004 26 18 0,000 0,03245605 0,0528675 ! response to fungus GO:0009620 19 18 0,000 0,03245605 0,05283009 ! peptide cross-linking GO:0018149 31 18 0,000 0,03245605 0,05279272 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03245605 0,05275541 ! heart process GO:0003015 27 18 0,000 0,03245605 0,05271816 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03245605 0,05268095 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03245605 0,0526438 ! somitogenesis GO:0001756 24 18 0,000 0,03245605 0,0526067 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03245605 0,05256966 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03245605 0,05253266 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03245605 0,05249572 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03245605 0,05245883 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03245605 0,05242199 ! vitamin transport GO:0051180 24 18 0,000 0,03245605 0,0523852 ! hormone transport GO:0009914 27 18 0,000 0,03245605 0,05234847 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03245605 0,05231178 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03245605 0,05227515 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03245605 0,05223857 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03245605 0,05220204 ! cell-cell recognition GO:0009988 20 18 0,000 0,03245605 0,05216556 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03245605 0,05212913 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03245605 0,05209275 ! regulation of glucose import GO:0046324 21 18 0,000 0,03245605 0,05205642 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03245605 0,05202015 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03245605 0,05198392 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03245605 0,05194775 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03245605 0,05191162 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03422892 0,05470918 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03422892 0,05467119 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,03422892 0,05463325 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03422892 0,05459536 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03422892 0,05455753 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03422892 0,05451975 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03422892 0,05448202 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03422892 0,05444434 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03422892 0,05440671 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03422892 0,05436914 ! regeneration GO:0031099 32 19 0,000 0,03422892 0,05433162 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03422892 0,05429415 ! response to alkaloid GO:0043279 32 19 0,000 0,03422892 0,05425673 ! sensory perception of taste GO:0050909 23 19 0,000 0,03422892 0,05421936 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03422892 0,05418205 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03422892 0,05414478 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03422892 0,05410757 ! peroxisome organization GO:0007031 29 19 0,000 0,03422892 0,05407041 ! digestive system process GO:0022600 30 19 0,000 0,03422892 0,0540333 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03422892 0,05399624 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03422892 0,05395923 ! response to vitamin A GO:0033189 26 19 0,000 0,03422892 0,05392227 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03422892 0,05388536 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03422892 0,0538485 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03422892 0,0538117 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03422892 0,05377494 ! response to starvation GO:0042594 30 19 0,000 0,03422892 0,05373823 ! sex determination GO:0007530 29 19 0,000 0,03422892 0,05370158 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03422892 0,05366497 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03422892 0,05362841 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03422892 0,05359191 ! cytolysis GO:0019835 20 19 0,000 0,03422892 0,05355545 ! renal system process GO:0003014 35 19 0,000 0,03422892 0,05351904 ! vasodilation GO:0042311 33 19 0,000 0,03422892 0,05348269 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03422892 0,05344638 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03422892 0,05341012 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03422892 0,05337391 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03422892 0,05333775 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03422892 0,05330163 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03422892 0,05326557 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03422892 0,05322956 ! sarcomere organization GO:0045214 23 19 0,000 0,03422892 0,05319359 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03422892 0,05315767 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03422892 0,0531218 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03422892 0,05308598 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03422892 0,05305021 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03422892 0,05301449 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03422892 0,05297881 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03422892 0,05294318 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03422892 0,0529076 ! protein stabilization GO:0050821 26 19 0,000 0,03422892 0,05287207 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03599864 0,05556837 ! iron ion transport GO:0006826 37 20 0,000 0,03599864 0,0555311 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03599864 0,05549388 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03599864 0,05545672 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03599864 0,0554196 ! response to vitamin GO:0033273 29 20 0,000 0,03599864 0,05538253 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03599864 0,05534551 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03599864 0,05530853 ! spinal cord development GO:0021510 31 20 0,000 0,03599864 0,05527161 ! response to ethanol GO:0045471 37 20 0,000 0,03599864 0,05523474 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03599864 0,05519792 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03599864 0,05516114 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03599864 0,05512442 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03599864 0,05508774 ! chromosome condensation GO:0030261 31 20 0,000 0,03599864 0,05505111 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03599864 0,05501454 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03599864 0,05497801 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03599864 0,05494152 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03599864 0,05490509 ! pallium development GO:0021543 38 20 0,000 0,03599864 0,05486871 ! DNA modification GO:0006304 28 20 0,000 0,03599864 0,05483237 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03599864 0,05479608 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03599864 0,05475984 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03599864 0,05472365 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03599864 0,0546875 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03599864 0,0546514 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,03599864 0,05461535 ! collagen catabolic process GO:0030574 25 20 0,000 0,03599864 0,05457935 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03599864 0,0545434 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03599864 0,05450749 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03599864 0,05447163 ! actin filament-based movement GO:0030048 34 20 0,000 0,03599864 0,05443582 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03776522 0,05706965 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03776522 0,05703218 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,03776522 0,05699476 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03776522 0,05695739 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,03776522 0,05692006 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03776522 0,05688279 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03776522 0,05684556 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03776522 0,05680838 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03776522 0,05677125 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03776522 0,05673417 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03776522 0,05669714 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03776522 0,05666015 ! protein amino acid acylation GO:0043543 37 21 0,000 0,03776522 0,05662322 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03776522 0,05658633 ! vesicle docking GO:0048278 27 21 0,000 0,03776522 0,05654949 ! phototransduction GO:0007602 25 21 0,000 0,03776522 0,0565127 ! dendrite development GO:0016358 35 21 0,000 0,03776522 0,05647595 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03776522 0,05643925 ! ovarian follicle development GO:0001541 30 21 0,000 0,03776522 0,05640261 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,03776522 0,056366 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03776522 0,05632945 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03776522 0,05629294 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03776522 0,05625649 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03776522 0,05622007 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,03776522 0,05618371 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03776522 0,05614739 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03776522 0,05611112 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03776522 0,0560749 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03776522 0,05603872 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03776522 0,05600259 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03776522 0,0559665 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03776522 0,05593047 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03776522 0,05589447 ! fatty acid transport GO:0015908 30 21 0,000 0,03776522 0,05585853 ! immunoglobulin production GO:0002377 33 21 0,000 0,03776522 0,05582263 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,03776522 0,05578678 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,03776522 0,05575097 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03776522 0,05571521 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03776522 0,0556795 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,03776522 0,05564383 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03776522 0,0556082 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03776522 0,05557263 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03776522 0,05553709 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03776522 0,05550161 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03776522 0,05546616 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03776522 0,05543077 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03776522 0,05539542 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03776522 0,05536011 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03776522 0,05532485 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03776522 0,05528963 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,03952867 0,05783457 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,03952867 0,0577978 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,03952867 0,05776108 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,03952867 0,0577244 ! viral genome replication GO:0019079 29 22 0,000 0,03952867 0,05768778 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,03952867 0,0576512 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,03952867 0,05761466 ! leukocyte adhesion GO:0007159 38 22 0,000 0,03952867 0,05757817 ! molting cycle process GO:0022404 40 22 0,000 0,03952867 0,05754173 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,03952867 0,05750534 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,03952867 0,05746899 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,03952867 0,05743268 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,03952867 0,05739642 ! vasculogenesis GO:0001570 33 22 0,000 0,03952867 0,05736021 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,03952867 0,05732405 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,03952867 0,05728792 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,03952867 0,05725185 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,03952867 0,05721582 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,03952867 0,05717983 ! lysosome organization GO:0007040 37 22 0,000 0,03952867 0,05714389 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,03952867 0,057108 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,03952867 0,05707215 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,03952867 0,05703635 ! regulation of behavior GO:0050795 38 22 0,000 0,03952867 0,05700059 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,03952867 0,05696487 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,03952867 0,0569292 ! membrane depolarization GO:0051899 35 22 0,000 0,03952867 0,05689358 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,03952867 0,056858 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,03952867 0,05682246 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,03952867 0,05678697 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,03952867 0,05675152 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,03952867 0,05671612 ! neural tube closure GO:0001843 33 22 0,000 0,03952867 0,05668076 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,03952867 0,05664544 ! protein tetramerization GO:0051262 39 22 0,000 0,03952867 0,05661017 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,04128898 0,05909437 ! neuron fate commitment GO:0048663 32 23 0,000 0,04128898 0,05905762 ! embryonic pattern specification GO:0009880 31 23 0,000 0,04128898 0,05902092 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,04128898 0,05898426 ! myelination GO:0042552 35 23 0,000 0,04128898 0,05894765 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,04128898 0,05891108 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,04128898 0,05887456 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,04128898 0,05883808 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,04128898 0,05880165 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,04128898 0,05876526 ! vesicle targeting GO:0006903 32 23 0,000 0,04128898 0,05872892 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,04128898 0,05869262 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,04128898 0,05865637 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,04128898 0,05862016 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,04128898 0,058584 ! interaction with host GO:0051701 37 23 0,000 0,04128898 0,05854788 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,04128898 0,0585118 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,04128898 0,05847578 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,04128898 0,05843979 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,04128898 0,05840385 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,04128898 0,05836795 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,04128898 0,0583321 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,04128898 0,05829629 ! pentose metabolic process GO:0019321 31 23 0,000 0,04128898 0,05826053 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,04128898 0,05822481 ! spermatid development GO:0007286 33 23 0,000 0,04128898 0,05818913 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,04128898 0,0581535 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,04128898 0,05811791 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,04128898 0,05808236 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,04128898 0,05804686 ! telomere organization GO:0032200 32 23 0,000 0,04128898 0,0580114 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,04128898 0,05797598 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,04128898 0,05794061 ! regulation of amine transport GO:0051952 38 23 0,000 0,04128898 0,05790528 ! liver development GO:0001889 40 23 0,000 0,04128898 0,05786999 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04304617 0,0602961 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04304617 0,0602594 ! initiation of viral infection GO:0019059 42 24 0,000 0,04304617 0,06022274 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04304617 0,06018614 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04304617 0,06014957 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04304617 0,06011305 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04304617 0,06007657 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,04304617 0,06004014 ! fat cell differentiation GO:0045444 37 24 0,000 0,04304617 0,06000375 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04304617 0,05996741 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04304617 0,05993111 ! vacuole organization GO:0007033 39 24 0,000 0,04304617 0,05989485 ! receptor metabolic process GO:0043112 37 24 0,000 0,04304617 0,05985864 ! neural crest cell development GO:0014032 39 24 0,000 0,04304617 0,05982247 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,04304617 0,05978635 ! primary neural tube formation GO:0014020 35 24 0,000 0,04304617 0,05975027 ! negative regulation of cell development GO:0010721 56 24 0,000 0,04304617 0,05971423 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04304617 0,05967824 ! base-excision repair GO:0006284 31 24 0,000 0,04304617 0,05964228 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04304617 0,05960638 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,04304617 0,05957051 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,04304617 0,05953469 ! glutathione metabolic process GO:0006749 29 24 0,000 0,04304617 0,05949891 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,04304617 0,05946318 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04304617 0,05942749 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04304617 0,05939184 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04480024 0,06177491 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04480024 0,0617379 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04480024 0,06170093 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04480024 0,061664 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04480024 0,06162712 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04480024 0,06159029 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,04480024 0,06155349 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,04480024 0,06151675 ! peptide transport GO:0015833 43 25 0,000 0,04480024 0,06148004 ! male gonad development GO:0008584 33 25 0,000 0,04480024 0,06144338 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04480024 0,06140676 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04480024 0,06137019 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04480024 0,06133366 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04480024 0,06129717 ! phospholipid transport GO:0015914 35 25 0,000 0,04480024 0,06126073 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04480024 0,06122433 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04480024 0,06118797 ! detection of light stimulus GO:0009583 30 25 0,000 0,04480024 0,06115166 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,04480024 0,06111539 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04480024 0,06107916 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04480024 0,06104298 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04480024 0,06100684 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04655119 0,06335369 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,04655119 0,06331623 ! translational initiation GO:0006413 43 26 0,000 0,04655119 0,06327881 ! regulation of pH GO:0006885 36 26 0,000 0,04655119 0,06324143 ! circadian rhythm GO:0007623 42 26 0,000 0,04655119 0,0632041 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04655119 0,06316681 ! post-embryonic development GO:0009791 42 26 0,000 0,04655119 0,06312956 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,04655119 0,06309236 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04655119 0,06305521 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04655119 0,06301809 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,04655119 0,06298102 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,04655119 0,062944 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04655119 0,06290702 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04655119 0,06287008 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04655119 0,06283318 ! regulation of coagulation GO:0050818 39 26 0,000 0,04655119 0,06279633 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,04829904 0,06511593 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,04829904 0,06507779 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,04829904 0,06503969 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,04829904 0,06500163 ! membrane docking GO:0022406 39 27 0,000 0,04829904 0,06496362 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,04829904 0,06492565 ! catechol metabolic process GO:0009712 43 27 0,000 0,04829904 0,06488772 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,04829904 0,06484984 ! acute-phase response GO:0006953 42 27 0,000 0,04829904 0,06481201 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,04829904 0,06477422 ! myofibril assembly GO:0030239 36 27 0,000 0,04829904 0,06473647 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,04829904 0,06469877 ! response to ionizing radiation GO:0010212 47 27 0,000 0,04829904 0,06466111 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,04829904 0,06462349 ! natural killer cell activation GO:0030101 35 27 0,000 0,04829904 0,06458592 ! lipid oxidation GO:0034440 38 27 0,000 0,04829904 0,06454839 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,04829904 0,06451091 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,04829904 0,06447347 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,04829904 0,06443607 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,04829904 0,06439871 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 0,000 0,04829904 0,0643614 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,05004378 0,06664776 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,05004378 0,06660919 ! phenol metabolic process GO:0018958 44 28 0,000 0,05004378 0,06657067 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,05004378 0,06653219 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,05004378 0,06649375 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,05004378 0,06645536 ! cell junction assembly GO:0034329 56 28 0,000 0,05004378 0,06641701 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,05004378 0,06637871 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,05004378 0,06634045 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,05004378 0,06630224 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,05004378 0,06626407 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,05004378 0,06622594 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,05004378 0,06618786 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,05004378 0,06614982 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,05004378 0,06611182 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,05004378 0,06607387 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,05004378 0,06603596 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,05004378 0,0659981 ! mesoderm formation GO:0001707 46 28 0,000 0,05004378 0,06596028 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,05004378 0,0659225 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,05004378 0,06588476 ! ensheathment of neurons GO:0007272 43 28 0,000 0,05004378 0,06584707 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,05004378 0,06580942 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,05004378 0,06577182 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,05004378 0,06573426 ! neural tube formation GO:0001841 41 28 0,000 0,05004378 0,06569674 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,05004378 0,06565926 ! placenta development GO:0001890 37 28 0,000 0,05004378 0,06562183 ! regulation of B cell activation GO:0050864 42 28 0,000 0,05004378 0,06558444 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,05178542 0,06782828 ! regulation of innate immune response GO:0045088 38 29 0,000 0,05178542 0,06778967 ! ovulation cycle process GO:0022602 41 29 0,000 0,05178542 0,06775111 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,05178542 0,0677126 ! protein targeting to membrane GO:0006612 53 29 0,000 0,05178542 0,06767412 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,05178542 0,06763569 ! mismatch repair GO:0006298 34 29 0,000 0,05178542 0,06759731 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,05178542 0,06755897 ! muscle cell development GO:0055001 38 29 0,000 0,05178542 0,06752067 ! formation of primary germ layer GO:0001704 48 29 0,000 0,05178542 0,06748241 ! telencephalon development GO:0021537 52 29 0,000 0,05178542 0,0674442 ! eye morphogenesis GO:0048592 51 29 0,000 0,05178542 0,06740603 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,05178542 0,06736791 ! tissue homeostasis GO:0001894 42 29 0,000 0,05178542 0,06732982 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,05352396 0,06955091 ! collagen metabolic process GO:0032963 40 30 0,000 0,05352396 0,06951164 ! organic anion transport GO:0015711 51 30 0,000 0,05352396 0,06947241 ! cholesterol transport GO:0030301 46 30 0,000 0,05352396 0,06943323 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,05352396 0,06939409 ! spliceosome assembly GO:0000245 49 30 0,000 0,05352396 0,069355 ! spindle organization GO:0007051 37 30 0,000 0,05352396 0,06931594 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,05352396 0,06927694 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,05352396 0,06923797 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,05352396 0,06919905 ! ceramide metabolic process GO:0006672 43 30 0,000 0,05352396 0,06916018 ! ovulation cycle GO:0042698 43 30 0,000 0,05352396 0,06912135 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,05352396 0,06908256 ! adult locomotory behavior GO:0008344 47 30 0,000 0,05352396 0,06904381 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,05352396 0,06900511 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,05352396 0,06896645 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,05352396 0,06892784 ! response to heat GO:0009408 41 30 0,000 0,05352396 0,06888927 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,05352396 0,06885074 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,05352396 0,06881225 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,05525942 0,07100373 ! negative regulation of secretion GO:0051048 49 31 0,000 0,05525942 0,07096408 ! mammary gland development GO:0030879 57 31 0,000 0,05525942 0,07092448 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,05525942 0,07088493 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,05525942 0,07084541 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,05525942 0,07080595 ! odontogenesis GO:0042476 50 31 0,000 0,05525942 0,07076652 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,05525942 0,07072714 ! segmentation GO:0035282 41 31 0,000 0,05525942 0,0706878 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,05525942 0,07064851 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,05525942 0,07060926 ! metanephros development GO:0001656 58 31 0,000 0,05525942 0,07057006 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,05525942 0,07053089 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,05525942 0,07049178 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,05525942 0,0704527 ! cell fate specification GO:0001708 37 31 0,000 0,05525942 0,07041367 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,05525942 0,07037468 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,05525942 0,07033573 ! RNA modification GO:0009451 40 31 0,000 0,05525942 0,07029683 ! regulation of muscle development GO:0048634 48 32 0,000 0,0569918 0,07246055 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,0569918 0,07242052 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,0569918 0,07238053 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,0569918 0,07234058 ! meiosis I GO:0007127 52 32 0,000 0,0569918 0,07230068 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,0569918 0,07226083 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,0569918 0,07222101 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,0569918 0,07218124 ! peripheral nervous system development GO:0007422 53 32 0,000 0,0569918 0,07214152 ! regulation of protein stability GO:0031647 48 32 0,000 0,0569918 0,07210184 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,0569918 0,0720622 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,0569918 0,0720226 ! cytokine production GO:0001816 44 32 0,000 0,0569918 0,07198305 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,0569918 0,07194354 ! vesicle localization GO:0051648 47 32 0,000 0,0569918 0,07190408 ! RNA export from nucleus GO:0006405 44 33 0,000 0,0587211 0,07404524 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,0587211 0,07400467 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,0587211 0,07396414 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,0587211 0,07392366 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,0587211 0,07388322 ! sister chromatid segregation GO:0000819 46 33 0,000 0,0587211 0,07384282 ! ear morphogenesis GO:0042471 42 33 0,000 0,0587211 0,07380247 ! actomyosin structure organization GO:0031032 43 33 0,000 0,0587211 0,07376217 ! cell junction organization GO:0034330 63 33 0,000 0,0587211 0,0737219 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,0587211 0,07368168 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,0587211 0,07364151 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,0587211 0,07360138 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,0587211 0,07356129 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,0587211 0,07352124 ! female gonad development GO:0008585 49 33 0,000 0,0587211 0,07348124 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,0587211 0,07344129 ! positive regulation of cell development GO:0010720 54 33 0,000 0,0587211 0,07340137 ! lipid homeostasis GO:0055088 55 33 0,000 0,0587211 0,0733615 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,0587211 0,07332167 ! regulation of proteolysis GO:0030162 50 33 0,000 0,0587211 0,07328189 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,0587211 0,07324215 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,0587211 0,07320245 ! cytokinesis GO:0000910 52 33 0,000 0,0587211 0,0731628 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,0587211 0,07312319 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,06044732 0,07523206 ! mRNA catabolic process GO:0006402 48 34 0,000 0,06044732 0,07519137 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,06044732 0,07515073 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,06044732 0,07511013 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,06044732 0,07506957 ! feeding behavior GO:0007631 45 34 0,000 0,06044732 0,07502906 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,06044732 0,07498859 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,06044732 0,07494816 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,06044732 0,07490778 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,06044732 0,07486745 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,06044732 0,07482715 ! neuron migration GO:0001764 46 34 0,000 0,06044732 0,0747869 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,06044732 0,07474669 ! female gamete generation GO:0007292 43 34 0,000 0,06044732 0,07470653 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,06044732 0,0746664 ! aerobic respiration GO:0009060 47 34 0,000 0,06044732 0,07462633 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,06044732 0,07458629 ! embryonic organ development GO:0048568 45 34 0,000 0,06044732 0,0745463 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,06044732 0,07450635 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,06217048 0,07658924 ! Notch signaling pathway GO:0007219 56 35 0,000 0,06217048 0,07654824 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,06217048 0,07650728 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,06217048 0,07646637 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,06217048 0,0764255 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,06217048 0,07638468 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,06217048 0,07634389 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,06217048 0,07630316 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,06217048 0,07626246 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,06217048 0,07622181 ! glycogen metabolic process GO:0005977 48 35 0,000 0,06217048 0,0761812 ! pigment metabolic process GO:0042440 61 35 0,000 0,06217048 0,07614064 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,06217048 0,07610011 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,06217048 0,07605963 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,06389058 0,07812245 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,06389058 0,07808094 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,06389058 0,07803948 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,06389058 0,07799806 ! negative regulation of binding GO:0051100 58 36 0,000 0,06389058 0,07795668 ! organic ether metabolic process GO:0018904 46 36 0,000 0,06389058 0,07791534 ! tissue remodeling GO:0048771 62 36 0,000 0,06389058 0,07787405 ! neural tube development GO:0021915 50 36 0,000 0,06389058 0,07783281 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,06389058 0,0777916 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,06389058 0,07775044 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,06389058 0,07770933 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,06389058 0,07766825 ! glucan metabolic process GO:0044042 49 36 0,000 0,06389058 0,07762723 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,06560762 0,07967135 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,06560762 0,0796293 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,06560762 0,07958731 ! ion transmembrane transport GO:0034220 56 37 0,000 0,06560762 0,07954535 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,06560762 0,07950344 ! regulation of protein secretion GO:0050708 51 37 0,000 0,06560762 0,07946158 ! amino acid activation GO:0043038 52 37 0,000 0,06560762 0,07941975 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,06560762 0,07937798 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,06732161 0,08140889 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,06732161 0,08136611 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,06732161 0,08132338 ! phagocytosis GO:0006909 60 38 0,000 0,06732161 0,08128069 ! mesenchymal cell development GO:0014031 64 38 0,000 0,06732161 0,08123804 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,06732161 0,08119544 ! maintenance of location in cell GO:0051651 69 38 0,000 0,06732161 0,08115289 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,06903256 0,08317176 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,06903256 0,08312821 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,06903256 0,08308471 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,06903256 0,08304126 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,06903256 0,08299785 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,06903256 0,08295448 ! male sex differentiation GO:0046661 53 39 0,000 0,06903256 0,08291116 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,06903256 0,08286789 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,06903256 0,08282466 ! JNK cascade GO:0007254 54 39 0,000 0,06903256 0,08278148 ! cell growth GO:0016049 61 39 0,000 0,06903256 0,08273834 ! synapse organization GO:0050808 55 39 0,000 0,06903256 0,08269525 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,07074046 0,08469706 ! response to calcium ion GO:0051592 58 40 0,000 0,07074046 0,084653 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,07074046 0,08460897 ! regulation of tube size GO:0035150 60 40 0,000 0,07074046 0,084565 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,07074046 0,08452107 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,07074046 0,08447719 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,07074046 0,08443335 ! peptide metabolic process GO:0006518 56 40 0,000 0,07074046 0,08438955 ! inner ear development GO:0048839 57 40 0,000 0,07074046 0,08434581 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,07074046 0,0843021 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,07074046 0,08425845 ! double-strand break repair GO:0006302 67 40 0,000 0,07074046 0,08421483 ! B cell differentiation GO:0030183 62 40 0,000 0,07074046 0,08417127 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,07074046 0,08412774 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,07074046 0,08408427 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,07074046 0,08404084 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,07244533 0,08602181 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,07244533 0,08597743 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,07244533 0,08593309 ! glucose transport GO:0015758 52 41 0,000 0,07244533 0,08588879 ! endosome transport GO:0016197 71 41 0,000 0,07244533 0,08584454 ! striated muscle contraction GO:0006941 62 41 0,000 0,07244533 0,08580034 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,07244533 0,08575618 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,07244533 0,08571207 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,07244533 0,085668 ! biopolymer methylation GO:0043414 62 41 0,000 0,07244533 0,08562397 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,07244533 0,08558 ! mitochondrial transport GO:0006839 60 42 0,000 0,07414717 0,08754542 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,07414717 0,0875005 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,07414717 0,08745563 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,07414717 0,08741081 ! cellular component disassembly GO:0022411 64 42 0,000 0,07414717 0,08736603 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,07414717 0,08732129 ! hexose transport GO:0008645 54 42 0,000 0,07414717 0,0872766 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,07414717 0,08723196 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,07414717 0,08718736 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,07414717 0,08714281 ! excretion GO:0007588 63 42 0,000 0,07414717 0,0870983 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,07414717 0,08705384 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,07414717 0,08700943 ! regulation of cell shape GO:0008360 78 42 0,000 0,07414717 0,08696506 ! positive regulation of binding GO:0051099 59 43 0,000 0,07584598 0,08891221 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,07584598 0,08886691 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,07584598 0,08882166 ! leukocyte migration GO:0050900 60 43 0,000 0,07584598 0,08877646 ! neuromuscular process GO:0050905 79 43 0,000 0,07584598 0,08873131 ! activation of caspase activity GO:0006919 65 43 0,000 0,07584598 0,0886862 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,07584598 0,08864113 ! tRNA processing GO:0008033 49 43 0,000 0,07584598 0,08859611 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,07584598 0,08855114 ! vesicle organization GO:0016050 79 43 0,000 0,07584598 0,08850622 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,07584598 0,08846133 ! methylation GO:0032259 64 43 0,000 0,07584598 0,0884165 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,07754177 0,09034755 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,07754177 0,09030181 ! glycolysis GO:0006096 53 44 0,000 0,07754177 0,09025611 ! regulation of action potential GO:0001508 71 44 0,000 0,07754177 0,09021046 ! regulation of ion transport GO:0043269 57 44 0,000 0,07754177 0,09016485 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,07754177 0,09011929 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,07754177 0,09007377 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,07754177 0,09002831 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,07754177 0,08998288 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,07754177 0,08993751 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,07754177 0,08989217 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,07754177 0,08984689 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,07754177 0,08980165 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,07923455 0,09171588 ! RNA catabolic process GO:0006401 64 45 0,000 0,07923455 0,09166975 ! positive regulation of defense response GO:0031349 59 45 0,000 0,07923455 0,09162366 ! regulation of translational initiation GO:0006446 64 45 0,000 0,07923455 0,09157762 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,07923455 0,09153162 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,07923455 0,09148567 ! cell recognition GO:0008037 58 45 0,000 0,07923455 0,09143977 ! cell maturation GO:0048469 60 45 0,000 0,07923455 0,09139391 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,07923455 0,0913481 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,08092432 0,09324946 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,08092432 0,09320277 ! cell redox homeostasis GO:0045454 63 46 0,000 0,08092432 0,09315612 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,08092432 0,09310952 ! regulation of ossification GO:0030278 71 46 0,000 0,08092432 0,09306297 ! histone modification GO:0016570 68 46 0,000 0,08092432 0,09301646 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,08092432 0,09297 ! response to UV GO:0009411 75 46 0,000 0,08092432 0,09292358 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,08261108 0,09481312 ! viral infectious cycle GO:0019058 71 47 0,000 0,08261108 0,09476583 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,08261108 0,09471859 ! endocrine system development GO:0035270 83 47 0,000 0,08261108 0,09467139 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,08261108 0,09462425 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,08261108 0,09457715 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,08261108 0,09453009 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,08261108 0,09448309 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,08261108 0,09443613 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 0,000 0,08261108 0,09438921 ! chloride transport GO:0006821 67 48 0,000 0,08429485 0,09626522 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,08429485 0,09621744 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,08429485 0,09616972 ! response to temperature stimulus GO:0009266 62 48 0,000 0,08429485 0,09612204 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,08429485 0,0960744 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,08429485 0,09602682 ! gastrulation GO:0007369 73 48 0,000 0,08429485 0,09597928 ! heart morphogenesis GO:0003007 65 48 0,000 0,08429485 0,09593179 ! regulation of DNA replication GO:0006275 75 48 0,000 0,08429485 0,09588435 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,08429485 0,09583695 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,08429485 0,0957896 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,08429485 0,0957423 ! regulation of endocytosis GO:0030100 63 48 0,000 0,08429485 0,09569504 ! nuclear export GO:0051168 69 48 0,000 0,08429485 0,09564783 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,08429485 0,09560066 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,08429485 0,09555355 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,08597562 0,0974108 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,08597562 0,09736284 ! sensory perception of smell GO:0007608 61 49 0,000 0,08597562 0,09731492 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,08597562 0,09726705 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,08597562 0,09721923 ! RNA elongation GO:0006354 62 49 0,000 0,08597562 0,09717146 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,08597562 0,09712373 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,08597562 0,09707605 ! germ cell development GO:0007281 68 49 0,000 0,08597562 0,09702842 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,08597562 0,09698083 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,08597562 0,09693329 ! cartilage development GO:0051216 70 49 0,000 0,08597562 0,0968858 ! maintenance of location GO:0051235 84 49 0,000 0,08597562 0,09683836 ! regulation of actin filament length GO:0030832 72 50 0,000 0,0876534 0,09867979 ! ear development GO:0043583 72 50 0,000 0,0876534 0,09863152 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,0876534 0,09858329 ! membrane fusion GO:0006944 80 50 0,000 0,0876534 0,0985351 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,0876534 0,09848697 ! lipid modification GO:0030258 73 50 0,000 0,0876534 0,09843888 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,0876534 0,09839084 ! proton transport GO:0015992 75 50 0,000 0,0876534 0,09834284 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,0876534 0,09829489 ! positive regulation of secretion GO:0051047 71 51 0,000 0,0893282 0,1001242 ! hydrogen transport GO:0006818 77 51 0,000 0,0893282 0,10007543 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,0893282 0,10002671 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,0893282 0,09997803 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,0893282 0,09992941 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,0893282 0,09988083 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,0893282 0,09983229 ! adult behavior GO:0030534 80 51 0,000 0,0893282 0,09978381 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,0893282 0,09973537 ! transition metal ion transport GO:0000041 74 52 0,000 0,09100002 0,10155267 ! regulation of cellular component size GO:0032535 74 52 0,000 0,09100002 0,10150342 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,09100002 0,10145421 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,09100002 0,10140506 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,09100002 0,10135595 ! establishment of organelle localization GO:0051656 85 52 0,000 0,09100002 0,10130689 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,09266887 0,10311485 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,09266887 0,10306499 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,09266887 0,10301517 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,09266887 0,10296541 ! kidney development GO:0001822 90 53 0,000 0,09266887 0,10291569 ! single fertilization GO:0007338 59 53 0,000 0,09266887 0,10286602 ! cell projection assembly GO:0030031 76 53 0,000 0,09266887 0,1028164 ! amino acid transport GO:0006865 84 54 0,000 0,09433474 0,10461423 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,09433474 0,10456381 ! regulation of mitosis GO:0007088 84 54 0,000 0,09433474 0,10451345 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,09433474 0,10446313 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,09433474 0,10441285 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,09433474 0,10436263 ! DNA catabolic process GO:0006308 67 54 0,000 0,09433474 0,10431246 ! detection of external stimulus GO:0009581 66 54 0,000 0,09433474 0,10426233 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,09433474 0,10421225 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,09433474 0,10416222 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,09433474 0,10411224 ! exocytosis GO:0006887 74 55 0,000 0,09599766 0,1058967 ! mesoderm development GO:0007498 76 55 0,000 0,09599766 0,10584593 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,09599766 0,10579522 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,09599766 0,10574455 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,09765762 0,10752155 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,09765762 0,10747011 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,09765762 0,10741871 ! carbohydrate transport GO:0008643 74 57 0,000 0,09931462 0,10918912 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,09931462 0,10913695 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,09931462 0,10908483 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,09931462 0,10903276 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,09931462 0,10898074 ! camera-type eye development GO:0043010 88 57 0,000 0,09931462 0,10892877 ! secondary metabolic process GO:0019748 84 57 0,000 0,09931462 0,10887685 ! developmental maturation GO:0021700 75 57 0,000 0,09931462 0,10882498 ! gonad development GO:0008406 79 57 0,000 0,09931462 0,10877316 ! viral reproductive process GO:0022415 87 58 0,000 0,10096868 0,11053211 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,10096868 0,11047952 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,10096868 0,11042699 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,10096868 0,11037451 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,10261979 0,11212614 ! activation of MAPK activity GO:0000187 84 59 0,000 0,10261979 0,1120729 ! lung development GO:0030324 94 59 0,000 0,10261979 0,11201971 ! actin filament organization GO:0007015 95 59 0,000 0,10261979 0,11196657 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,10261979 0,11191348 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,10261979 0,11186044 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,10426797 0,11360319 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,10426797 0,1135494 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,10426797 0,11349566 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,10426797 0,11344197 ! regulation of heart contraction GO:0008016 91 60 0,000 0,10426797 0,11338833 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,10426797 0,11333475 ! fertilization GO:0009566 68 60 0,000 0,10426797 0,11328121 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,10426797 0,11322773 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,10591321 0,11496007 ! meiosis GO:0007126 96 61 0,000 0,10591321 0,11490584 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,10591321 0,11485167 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,10591321 0,11479754 ! urogenital system development GO:0001655 101 61 0,000 0,10591321 0,11474347 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,10591321 0,11468945 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,10591321 0,11463547 ! extracellular matrix organization GO:0030198 103 61 0,000 0,10591321 0,11458155 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,10591321 0,11452768 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,10755553 0,11624892 ! neurotransmitter transport GO:0006836 81 62 0,000 0,10755553 0,11619432 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,10755553 0,11613977 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,10755553 0,11608527 ! respiratory tube development GO:0030323 99 62 0,000 0,10755553 0,11603082 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,10755553 0,11597642 ! meiotic cell cycle GO:0051321 97 62 0,000 0,10755553 0,11592208 ! organelle localization GO:0051640 96 62 0,000 0,10755553 0,11586778 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,10919492 0,1175788 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,10919492 0,11752378 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,10919492 0,11746881 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,10919492 0,11741389 ! viral reproduction GO:0016032 92 63 0,000 0,10919492 0,11735902 ! regulation of lipase activity GO:0060191 109 63 0,000 0,10919492 0,11730421 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,11083139 0,11900663 ! negative regulation of cell size GO:0045792 108 64 0,000 0,11083139 0,1189511 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,11083139 0,11889562 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,11083139 0,11884019 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,11083139 0,11878481 ! hexose catabolic process GO:0019320 82 64 0,000 0,11083139 0,11872949 ! respiratory system development GO:0060541 100 64 0,000 0,11083139 0,11867421 ! adaptive immune response GO:0002250 94 64 0,000 0,11083139 0,11861899 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,11246496 0,12031135 ! B cell activation GO:0042113 104 65 0,000 0,11246496 0,12025542 ! defense response to bacterium GO:0042742 73 65 0,000 0,11246496 0,12019954 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,11246496 0,12014371 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,11246496 0,12008793 ! activation of immune response GO:0002253 83 65 0,000 0,11246496 0,1200322 ! protein oligomerization GO:0051259 100 65 0,000 0,11246496 0,11997653 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,11409561 0,12165967 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,11409561 0,12160329 ! antigen processing and presentation GO:0019882 96 66 0,000 0,11409561 0,12154697 ! axon guidance GO:0007411 99 66 0,000 0,11409561 0,1214907 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,11409561 0,12143448 ! regulation of immune effector process GO:0002697 101 66 0,000 0,11409561 0,12137831 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,11572336 0,12305305 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,11572336 0,12299618 ! acute inflammatory response GO:0002526 92 68 0,000 0,11734822 0,12466554 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,11734822 0,12460799 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,11734822 0,12455049 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,11734822 0,12449304 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,11734822 0,12443564 ! rhythmic process GO:0048511 105 68 0,000 0,11734822 0,1243783 ! inorganic anion transport GO:0015698 93 68 0,000 0,11734822 0,12432101 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,11897018 0,12598132 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,11897018 0,12592334 ! response to drug GO:0042493 108 69 0,000 0,11897018 0,12586542 ! response to metal ion GO:0010038 103 70 0,000 0,12058926 0,12751967 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,12058926 0,12746107 ! humoral immune response GO:0006959 86 70 0,000 0,12058926 0,12740252 ! amine transport GO:0015837 101 70 0,000 0,12058926 0,12734403 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,12058926 0,12728559 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,12058926 0,1272272 ! regulation of catabolic process GO:0009894 106 70 0,000 0,12058926 0,12716886 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,12220545 0,12881418 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,12220545 0,12875517 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,12220545 0,12869622 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,12220545 0,12863732 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,12220545 0,12857847 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,12381876 0,13021635 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 0,000 0,12381876 0,13015684 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,12381876 0,13009738 ! negative regulation of transport GO:0051051 116 73 0,000 0,12542921 0,1317293 ! regulation of blood pressure GO:0008217 107 73 0,000 0,12542921 0,13166918 ! tube morphogenesis GO:0035239 118 73 0,000 0,12542921 0,13160911 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,12542921 0,1315491 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,12542921 0,13148914 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,12703678 0,13311371 ! response to oxygen levels GO:0070482 137 74 0,000 0,12703678 0,1330531 ! digestion GO:0007586 97 74 0,000 0,12703678 0,13299253 ! protein import into nucleus GO:0006606 118 74 0,000 0,12703678 0,13293203 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,12703678 0,13287158 ! blood coagulation GO:0007596 116 75 0,000 0,12864149 0,13448883 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,12864149 0,13442773 ! negative regulation of growth GO:0045926 123 75 0,000 0,12864149 0,13436668 ! response to nutrient GO:0007584 104 75 0,000 0,12864149 0,13430569 ! nuclear import GO:0051170 121 75 0,000 0,12864149 0,13424475 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,12864149 0,13418387 ! amine biosynthetic process GO:0009309 97 76 0,000 0,13024335 0,13579315 ! tRNA metabolic process GO:0006399 95 76 0,000 0,13024335 0,13573163 ! response to unfolded protein GO:0006986 99 76 0,000 0,13024335 0,13567015 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,13024335 0,13560874 ! regulation of protein transport GO:0051223 114 76 0,000 0,13024335 0,13554737 GO:0070201|regulation of establishment of protein localization, ! cholesterol metabolic process GO:0008203 109 77 0,000 0,13184235 0,13714944 ! regulation of DNA binding GO:0051101 119 77 0,000 0,13184235 0,13708743 ! gland development GO:0048732 148 77 0,000 0,13184235 0,13702549 ! sex differentiation GO:0007548 105 77 0,000 0,13184235 0,1369636 ! protein ubiquitination GO:0016567 125 77 0,000 0,13184235 0,13690176 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,13184235 0,13683998 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,1334385 0,13843417 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,1334385 0,13837176 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,13503181 0,13996087 ! T cell activation GO:0042110 134 79 0,000 0,13503181 0,13989782 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,13503181 0,13983483 ! chromatin assembly GO:0031497 102 80 0,000 0,13662228 0,1414182 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,13662228 0,14135459 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,13662228 0,14129103 ! hemostasis GO:0007599 125 81 0,000 0,13820992 0,14286868 ! mRNA transport GO:0051028 121 81 0,000 0,13820992 0,1428045 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,13820992 0,14274038 ! response to protein stimulus GO:0051789 111 81 0,000 0,13820992 0,14267631 ! vitamin metabolic process GO:0006766 103 81 0,000 0,13820992 0,1426123 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,13820992 0,14254835 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 0,000 0,13979473 0,14411828 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,14137672 0,14568389 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,14137672 0,14561865 ! regulation of defense response GO:0031347 117 84 0,000 0,14295589 0,14717929 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,14295589 0,14711344 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,14295589 0,14704765 ! sterol metabolic process GO:0016125 120 84 0,000 0,14295589 0,14698191 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,14453224 0,14853626 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,14453224 0,14846992 ! rRNA metabolic process GO:0016072 107 85 0,000 0,14453224 0,14840364 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,14453224 0,14833742 ! transcription initiation GO:0006352 118 85 0,000 0,14453224 0,14827126 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,14453224 0,14820515 ! regulation of protein localization GO:0032880 132 85 0,000 0,14453224 0,14813911 ! regulation of membrane potential GO:0042391 128 85 0,000 0,14453224 0,14807312 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,14453224 0,14800719 ! cell cycle arrest GO:0007050 150 86 0,000 0,14610579 0,14955198 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,14610579 0,14948546 ! nucleosome organization GO:0034728 114 87 0,000 0,14767653 0,15102535 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,14767653 0,15095823 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,14767653 0,15089117 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,14767653 0,15082416 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,14767653 0,15075722 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,14767653 0,15069033 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,14924447 0,15222274 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,14924447 0,15215527 ! interphase GO:0051325 159 88 0,000 0,14924447 0,15208785 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,14924447 0,1520205 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,14924447 0,1519532 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,14924447 0,15188596 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,15080962 0,15341093 ! reproductive developmental process GO:0003006 127 89 0,000 0,15080962 0,15334311 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,15080962 0,15327535 ! regulation of T cell activation GO:0050863 128 89 0,000 0,15080962 0,15320765 ! leukocyte differentiation GO:0002521 143 90 0,000 0,15237198 0,15472651 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,15237198 0,15465823 ! hormone metabolic process GO:0042445 121 90 0,000 0,15237198 0,15459001 ! RNA localization GO:0006403 135 91 0,000 0,15393155 0,15610342 ! ATP metabolic process GO:0046034 137 91 0,000 0,15393155 0,15603462 ! response to virus GO:0009615 122 91 0,000 0,15393155 0,15596589 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,15548834 0,15747388 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,15548834 0,15740457 ! positive regulation of immune response GO:0050778 121 92 0,000 0,15548834 0,15733532 ! sulfur metabolic process GO:0006790 118 92 0,000 0,15548834 0,15726613 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,15704236 0,1587681 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,15704236 0,15869834 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,15704236 0,15862865 ! electron transport chain GO:0022900 123 94 0,000 0,15859361 0,16012524 ! response to oxidative stress GO:0006979 141 94 0,000 0,15859361 0,16005498 ! regulation of binding GO:0051098 151 95 0,000 0,16014209 0,16154684 ! angiogenesis GO:0001525 149 95 0,000 0,16014209 0,16147602 ! carboxylic acid transport GO:0046942 147 95 0,000 0,16014209 0,16140526 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,16168781 0,16289179 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,16168781 0,16282047 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,16168781 0,16274922 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,16168781 0,16267802 ! protein maturation GO:0051604 129 96 0,000 0,16168781 0,16260689 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,16323078 0,16408688 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,16323078 0,1640152 ! calcium ion transport GO:0006816 167 99 0,000 0,16630846 0,16703469 ! extracellular structure organization GO:0043062 156 99 0,000 0,16630846 0,16696178 ! protein import GO:0017038 156 99 0,000 0,16630846 0,16688894 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,16630846 0,16681616 ! regulation of translation GO:0006417 151 100 0,000 0,16784318 0,16828218 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,16784318 0,16820885 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,16784318 0,16813559 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,16784318 0,16806239 ! divalent metal ion transport GO:0070838 171 100 0,000 0,16784318 0,16798926 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,16784318 0,16791619 ! protein localization in organelle GO:0033365 161 100 0,000 0,16784318 0,16784318