pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/8573-10-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 2,000 2,936E-07 5,411E-04 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 2,000 1,573E-06 1,45E-03 ! hemoglobin biosynthetic process GO:0042541 5 5 1,000 1,181E-05 7,256E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,181E-05 5,442E-03 ! heart looping GO:0001947 5 5 1,000 1,181E-05 4,354E-03 ! muscle cell migration GO:0014812 5 5 1,000 1,181E-05 3,628E-03 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 1,000 1,181E-05 3,11E-03 ! positive regulation of monooxygenase activity GO:0032770 5 5 1,000 1,181E-05 2,721E-03 ! regulation of hormone metabolic process GO:0032350 5 5 1,000 1,181E-05 2,419E-03 ! positive regulation of erythrocyte differentiation GO:0045648 5 5 1,000 1,181E-05 2,177E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,771E-05 2,967E-03 GO:0018409|peptide or protein amino-terminal blocking, ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 1,771E-05 2,72E-03 ! thymus development GO:0048538 6 6 1,000 1,771E-05 2,51E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 1,771E-05 2,331E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 2,478E-05 3,044E-03 ! regulation of chemokine production GO:0032642 7 7 1,000 2,478E-05 2,854E-03 ! axis specification GO:0009798 7 7 1,000 2,478E-05 2,686E-03 ! hemoglobin metabolic process GO:0020027 7 7 1,000 2,478E-05 2,537E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 2,478E-05 2,403E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! induction of an organ GO:0001759 7 7 1,000 2,478E-05 2,283E-03 ! thyroid gland development GO:0030878 8 8 1,000 3,302E-05 2,897E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 3,302E-05 2,766E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 3,302E-05 2,646E-03 ! developmental induction GO:0031128 8 8 1,000 3,302E-05 2,535E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 3,302E-05 2,434E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 4,242E-05 3,007E-03 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 4,242E-05 2,896E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 4,242E-05 2,792E-03 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 4,242E-05 2,696E-03 ! positive regulation of oxidoreductase activity GO:0051353 9 9 1,000 4,242E-05 2,606E-03 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 5,3E-05 3,151E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 5,3E-05 3,052E-03 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 5,3E-05 2,96E-03 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 5,3E-05 2,873E-03 ! negative regulation of signal transduction GO:0009968 71 71 2,000 5,684E-05 2,993E-03 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 6,474E-05 3,314E-03 ! muscle maintenance GO:0046716 12 11 1,000 6,474E-05 3,225E-03 ! protein amino acid acetylation GO:0006473 11 11 1,000 6,474E-05 3,14E-03 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 6,474E-05 3,059E-03 GO:0006109|regulation of carbohydrate metabolic process, ! negative regulation of cell communication GO:0010648 76 76 2,000 6,972E-05 3,212E-03 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 7,764E-05 3,49E-03 ! collagen metabolic process GO:0032963 12 12 1,000 7,764E-05 3,407E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 9,17E-05 3,93E-03 ! ureteric bud development GO:0001657 13 13 1,000 9,17E-05 3,841E-03 ! neural crest cell migration GO:0001755 14 13 1,000 9,17E-05 3,756E-03 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 9,17E-05 3,674E-03 ! activation of JUN kinase activity GO:0007257 13 13 1,000 9,17E-05 3,596E-03 ! cellular iron ion homeostasis GO:0006879 14 14 1,000 1,069E-04 4,106E-03 ! protein amino acid acylation GO:0043543 14 14 1,000 1,069E-04 4,022E-03 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 1,233E-04 4,545E-03 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 1,233E-04 4,456E-03 ! pattern specification process GO:0007389 96 94 2,000 1,316E-04 4,666E-03 ! inner ear morphogenesis GO:0042472 16 16 1,000 1,408E-04 4,897E-03 ! iron ion homeostasis GO:0055072 16 16 1,000 1,408E-04 4,807E-03 ! cell fate specification GO:0001708 16 16 1,000 1,408E-04 4,719E-03 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,408E-04 4,635E-03 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 1,408E-04 4,554E-03 GO:0043507|positive regulation of JUN kinase activity, ! tissue remodeling GO:0048771 17 17 1,000 1,595E-04 5,069E-03 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 1,595E-04 4,983E-03 ! neural crest cell development GO:0014032 19 17 1,000 1,595E-04 4,9E-03 GO:0014033|neural crest cell differentiation, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 1,595E-04 4,82E-03 ! embryonic organ development GO:0048568 17 17 1,000 1,595E-04 4,742E-03 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 1,794E-04 5,247E-03 ! negative regulation of DNA binding GO:0043392 19 18 1,000 1,794E-04 5,165E-03 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 2,003E-04 5,68E-03 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 2,003E-04 5,594E-03 ! metanephros development GO:0001656 19 19 1,000 2,003E-04 5,511E-03 ! cellular response to oxidative stress GO:0034599 19 19 1,000 2,003E-04 5,43E-03 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 2,003E-04 5,351E-03 ! placenta development GO:0001890 19 19 1,000 2,003E-04 5,275E-03 ! negative regulation of binding GO:0051100 21 20 1,000 2,225E-04 5,775E-03 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 2,225E-04 5,695E-03 ! ear morphogenesis GO:0042471 21 21 1,000 2,457E-04 6,204E-03 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 2,457E-04 6,12E-03 ! negative regulation of protein transport GO:0051224 21 21 1,000 2,457E-04 6,039E-03 ! embryonic skeletal system development GO:0048706 22 22 1,000 2,702E-04 6,552E-03 ! maintenance of protein location in cell GO:0032507 23 22 1,000 2,702E-04 6,466E-03 ! epithelial cell differentiation GO:0030855 23 23 1,000 2,957E-04 6,987E-03 ! endocrine system development GO:0035270 23 23 1,000 2,957E-04 6,899E-03 ! regulation of JNK cascade GO:0046328 25 23 1,000 2,957E-04 6,813E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 3,224E-04 7,336E-03 ! glucose homeostasis GO:0042593 24 24 1,000 3,224E-04 7,247E-03 GO:0033500|carbohydrate homeostasis, ! maintenance of protein location GO:0045185 25 24 1,000 3,224E-04 7,159E-03 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 3,224E-04 7,074E-03 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 3,503E-04 7,594E-03 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 3,503E-04 7,506E-03 ! heart morphogenesis GO:0003007 25 25 1,000 3,503E-04 7,42E-03 ! positive regulation of cytokine production GO:0001819 25 25 1,000 3,503E-04 7,335E-03 ! maintenance of location in cell GO:0051651 27 26 1,000 3,792E-04 7,853E-03 ! inner ear development GO:0048839 27 27 1,000 4,093E-04 8,382E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 4,093E-04 8,29E-03 ! mesenchymal cell development GO:0014031 29 27 1,000 4,093E-04 8,2E-03 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 4,405E-04 8,73E-03 GO:0007254|JNK cascade, ! cartilage development GO:0051216 29 28 1,000 4,405E-04 8,638E-03 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 4,729E-04 9,174E-03 ! skeletal system morphogenesis GO:0048705 31 30 1,000 5,064E-04 9,722E-03 ! skeletal muscle fiber development GO:0048741 31 31 1,000 5,41E-04 0,01027899 ! regulation of intracellular transport GO:0032386 31 31 1,000 5,41E-04 0,0101741 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 5,41E-04 0,01007133 ! muscle fiber development GO:0048747 32 32 1,000 5,767E-04 0,01062914 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 5,767E-04 0,0105239 ! kidney development GO:0001822 32 32 1,000 5,767E-04 0,01042072 ! maintenance of location GO:0051235 33 32 1,000 5,767E-04 0,01031955 ! regulation of cellular response to stress GO:0080135 35 33 1,000 6,136E-04 0,01087337 ! regulation of neuron differentiation GO:0045664 34 33 1,000 6,136E-04 0,01076981 ! regulation of angiogenesis GO:0045765 35 34 1,000 6,516E-04 0,01132837 ! ear development GO:0043583 34 34 1,000 6,516E-04 0,0112225 ! positive regulation of cell migration GO:0030335 36 36 1,000 7,308E-04 0,01247158 ! negative regulation of growth GO:0045926 37 37 1,000 7,721E-04 0,01305568 ! urogenital system development GO:0001655 38 38 1,000 8,146E-04 0,01364776 ! regulation of homeostatic process GO:0032844 38 38 1,000 8,146E-04 0,01352481 ! activation of MAPK activity GO:0000187 39 39 1,000 8,581E-04 0,01412036 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 8,581E-04 0,01399541 ! positive regulation of cell motion GO:0051272 39 39 1,000 8,581E-04 0,01387264 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 9,953E-04 0,01595115 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 1,092E-03 0,01735457 ! regulation of DNA binding GO:0051101 47 45 1,000 1,142E-03 0,01799604 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 1,142E-03 0,01784354 ! tube morphogenesis GO:0035239 47 46 1,000 1,194E-03 0,01848707 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 1,194E-03 0,01833301 ! positive regulation of ligase activity GO:0051351 47 46 1,000 1,194E-03 0,0181815 ! regulation of catabolic process GO:0009894 48 47 1,000 1,246E-03 0,01882294 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 1,299E-03 0,0194703 ! gland development GO:0048732 51 49 1,000 1,354E-03 0,02012339 ! skeletal muscle tissue development GO:0007519 50 49 1,000 1,354E-03 0,0199624 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 1,354E-03 0,01980397 ! regulation of ligase activity GO:0051340 50 49 1,000 1,354E-03 0,01964804 ! negative regulation of transport GO:0051051 51 50 1,000 1,41E-03 0,02029498 ! regulation of neurogenesis GO:0050767 51 50 1,000 1,41E-03 0,02013765 ! anatomical structure homeostasis GO:0060249 51 50 1,000 1,41E-03 0,01998275 ! cell fate commitment GO:0045165 52 52 1,000 1,524E-03 0,02144019 ! response to hypoxia GO:0001666 53 53 1,000 1,583E-03 0,0220993 ! regulation of protein transport GO:0051223 53 53 1,000 1,583E-03 0,02193314 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 1,000 1,643E-03 0,02259357 ! in utero embryonic development GO:0001701 55 55 1,000 1,704E-03 0,02325893 ! regulation of nervous system development GO:0051960 57 56 1,000 1,766E-03 0,02392906 ! regulation of binding GO:0051098 60 57 1,000 1,829E-03 0,02460385 ! regulation of protein localization GO:0032880 58 57 1,000 1,829E-03 0,02442556 ! peptidyl-amino acid modification GO:0018193 61 59 1,000 1,958E-03 0,02596687 ! regulation of cell development GO:0060284 60 59 1,000 1,958E-03 0,0257814 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 2,092E-03 0,02734703 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 2,092E-03 0,02715444 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! morphogenesis of an epithelium GO:0002009 63 62 1,000 2,161E-03 0,02784713 GO:0060429|epithelium development, ! DNA packaging GO:0006323 66 66 1,000 2,445E-03 0,03129514 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 2,445E-03 0,03107932 ! striated muscle tissue development GO:0014706 69 67 1,000 2,519E-03 0,03179764 ! sensory perception of sound GO:0007605 71 69 1,000 2,67E-03 0,03347057 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 2,67E-03 0,03324442 ! wound healing GO:0042060 74 70 1,000 2,747E-03 0,0339727 ! muscle tissue development GO:0060537 72 70 1,000 2,747E-03 0,03374622 ! regulation of cell migration GO:0030334 71 71 1,000 2,825E-03 0,0344743 ! sensory organ development GO:0007423 72 72 1,000 2,904E-03 0,03520546 ! regulation of cytokine production GO:0001817 72 72 1,000 2,904E-03 0,03497535 ! response to oxidative stress GO:0006979 76 75 1,000 3,147E-03 0,03765955 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 3,23E-03 0,03840544 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 3,314E-03 0,03915399 ! regulation of protein modification process GO:0031399 79 78 1,000 3,399E-03 0,03990512 ! regulation of locomotion GO:0040012 79 79 1,000 3,486E-03 0,04065877 ! regulation of cell motion GO:0051270 79 79 1,000 3,486E-03 0,04040305 ! MAPKKK cascade GO:0000165 82 81 1,000 3,661E-03 0,04217334 ! tube development GO:0035295 83 81 1,000 3,661E-03 0,04191139 ! regulation of cellular localization GO:0060341 86 85 1,000 4,025E-03 0,04578811 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 4,025E-03 0,0455072 ! positive regulation of protein kinase activity GO:0045860 89 86 1,000 4,118E-03 0,0462796 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 4,118E-03 0,04599912 ! heart development GO:0007507 90 87 1,000 4,213E-03 0,04677053 ! positive regulation of transferase activity GO:0051347 91 88 1,000 4,308E-03 0,04754389 GO:0033674|positive regulation of kinase activity, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 4,405E-03 0,04831915 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 4,601E-03 0,05017025 ! tissue morphogenesis GO:0048729 94 93 1,000 4,801E-03 0,0520432 ! regulation of response to stress GO:0080134 97 94 1,000 4,902E-03 0,05283277 ! glycoprotein metabolic process GO:0009100 99 98 1,000 5,318E-03 0,05698285 ! anti-apoptosis GO:0006916 100 99 1,000 5,424E-03 0,05778784 ! muscle organ development GO:0007517 102 100 1,000 5,532E-03 0,05859408 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 5,532E-03 0,05825925 ! hemopoiesis GO:0030097 104 100 1,000 5,532E-03 0,05792824 ! rRNA transcription GO:0009303 5 5 0,000 5,802E-03 0,06041428 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 5,802E-03 0,06007488 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 5,802E-03 0,05973926 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 5,802E-03 0,05940738 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 5,802E-03 0,05907916 ! reproductive cellular process GO:0048610 5 5 0,000 5,802E-03 0,05875455 ! negative regulation of blood pressure GO:0045776 6 5 0,000 5,802E-03 0,05843349 ! prostate gland development GO:0030850 5 5 0,000 5,802E-03 0,05811591 ! metencephalon development GO:0022037 5 5 0,000 5,802E-03 0,05780177 ! water transport GO:0006833 5 5 0,000 5,802E-03 0,05749101 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 5,802E-03 0,05718357 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 5,802E-03 0,0568794 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 5,802E-03 0,05657846 ! glycerol metabolic process GO:0006071 5 5 0,000 5,802E-03 0,05628067 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 5,802E-03 0,05598601 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 5,802E-03 0,05569442 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 5,802E-03 0,05540585 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 5,802E-03 0,05512025 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 5,802E-03 0,05483758 ! filopodium assembly GO:0046847 7 5 0,000 5,802E-03 0,0545578 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 5,802E-03 0,05428085 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 5,802E-03 0,05400671 ! GTP metabolic process GO:0046039 5 5 0,000 5,802E-03 0,05373532 ! establishment of tissue polarity GO:0007164 5 5 0,000 5,802E-03 0,05346664 ! mRNA stabilization GO:0048255 5 5 0,000 5,802E-03 0,05320064 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 5,802E-03 0,05293727 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 5,802E-03 0,05267649 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 5,802E-03 0,05241828 ! social behavior GO:0035176 5 5 0,000 5,802E-03 0,05216258 ! macrophage chemotaxis GO:0048246 6 5 0,000 5,802E-03 0,05190936 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 5,802E-03 0,05165859 ! memory GO:0007613 5 5 0,000 5,802E-03 0,05141023 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 5,802E-03 0,05116425 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 5,802E-03 0,05092061 ! membrane hyperpolarization GO:0060081 5 5 0,000 5,802E-03 0,05067928 ! response to lipid GO:0033993 5 5 0,000 5,802E-03 0,05044023 ! erythrocyte maturation GO:0043249 5 5 0,000 5,802E-03 0,05020342 ! hippocampus development GO:0021766 6 5 0,000 5,802E-03 0,04996882 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 5,802E-03 0,04973641 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 5,802E-03 0,04950615 ! middle ear morphogenesis GO:0042474 5 5 0,000 5,802E-03 0,04927801 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 5,802E-03 0,04905196 ! mechanosensory behavior GO:0007638 5 5 0,000 5,802E-03 0,04882798 ! negative regulation of endocytosis GO:0045806 5 5 0,000 5,802E-03 0,04860604 ! response to interferon-gamma GO:0034341 5 5 0,000 5,802E-03 0,0483861 ! pseudouridine synthesis GO:0001522 5 5 0,000 5,802E-03 0,04816814 ! endocrine pancreas development GO:0031018 5 5 0,000 5,802E-03 0,04795214 ! pH reduction GO:0045851 5 5 0,000 5,802E-03 0,04773807 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 5,802E-03 0,0475259 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 5,802E-03 0,04731561 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 5,802E-03 0,04710717 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 5,802E-03 0,04690056 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 5,802E-03 0,04669576 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 5,802E-03 0,04649273 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 5,802E-03 0,04629146 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 5,802E-03 0,04609193 ! adrenal gland development GO:0030325 5 5 0,000 5,802E-03 0,04589411 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 5,802E-03 0,04569798 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 5,802E-03 0,04550352 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 5,802E-03 0,04531071 ! astrocyte differentiation GO:0048708 5 5 0,000 5,802E-03 0,04511953 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 5,802E-03 0,04492995 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 5,802E-03 0,04474196 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 5,802E-03 0,04455553 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 5,802E-03 0,04437066 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 5,802E-03 0,04418731 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 5,802E-03 0,04400547 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 5,802E-03 0,04382512 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 5,802E-03 0,04364624 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 5,802E-03 0,04346881 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 5,802E-03 0,04329283 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! phasic smooth muscle contraction GO:0014821 5 5 0,000 5,802E-03 0,04311826 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 5,802E-03 0,04294509 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 5,802E-03 0,04277331 ! response to ATP GO:0033198 5 5 0,000 5,802E-03 0,0426029 ! regulation of type I interferon production GO:0032479 5 5 0,000 5,802E-03 0,04243384 ! regulation of appetite GO:0032098 5 5 0,000 5,802E-03 0,04226612 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 5,802E-03 0,04209972 ! paraxial mesoderm development GO:0048339 5 5 0,000 5,802E-03 0,04193462 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 5,802E-03 0,04177081 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 5,802E-03 0,04160828 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 5,802E-03 0,04144701 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,802E-03 0,04128698 ! receptor clustering GO:0043113 5 5 0,000 5,802E-03 0,04112819 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 5,802E-03 0,04097061 ! fear response GO:0042596 5 5 0,000 5,802E-03 0,04081423 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 5,802E-03 0,04065904 ! lens development in camera-type eye GO:0002088 5 5 0,000 5,802E-03 0,04050503 ! retinol metabolic process GO:0042572 5 5 0,000 5,802E-03 0,04035218 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 5,802E-03 0,04020048 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 5,802E-03 0,04004992 ! positive regulation of exocytosis GO:0045921 6 5 0,000 5,802E-03 0,03990048 ! parturition GO:0007567 5 5 0,000 5,802E-03 0,03975215 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,802E-03 0,03960492 ! Schwann cell differentiation GO:0014037 5 5 0,000 5,802E-03 0,03945878 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 5,802E-03 0,03931371 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 5,802E-03 0,0391697 ! protein heterooligomerization GO:0051291 5 5 0,000 5,802E-03 0,03902674 ! regulation of gliogenesis GO:0014013 5 5 0,000 5,802E-03 0,03888483 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 5,802E-03 0,03874394 ! response to UV-B GO:0010224 5 5 0,000 5,802E-03 0,03860407 ! oligodendrocyte development GO:0014003 5 5 0,000 5,802E-03 0,03846521 ! hyaluronan metabolic process GO:0030212 5 5 0,000 5,802E-03 0,03832734 ! activated T cell proliferation GO:0050798 5 5 0,000 5,802E-03 0,03819046 ! interaction with symbiont GO:0051702 5 5 0,000 5,802E-03 0,03805455 ! cellular extravasation GO:0045123 5 5 0,000 5,802E-03 0,0379196 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 5,802E-03 0,03778561 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 5,802E-03 0,03765256 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 5,802E-03 0,03752045 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 5,802E-03 0,03738926 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 5,802E-03 0,03725898 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 5,802E-03 0,03712961 ! response to amine stimulus GO:0014075 5 5 0,000 5,802E-03 0,03700114 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 5,802E-03 0,03687355 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 5,802E-03 0,03674683 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 5,802E-03 0,03662099 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 5,802E-03 0,036496 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 5,802E-03 0,03637186 ! neuron recognition GO:0008038 5 5 0,000 5,802E-03 0,03624857 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 5,802E-03 0,03612611 ! decidualization GO:0046697 5 5 0,000 5,802E-03 0,03600447 ! hair follicle maturation GO:0048820 5 5 0,000 5,802E-03 0,03588365 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 5,802E-03 0,03576364 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 5,802E-03 0,03564443 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,802E-03 0,03552601 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 5,802E-03 0,03540837 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 5,802E-03 0,03529151 ! postreplication repair GO:0006301 5 5 0,000 5,802E-03 0,03517542 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 5,802E-03 0,03506009 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 5,802E-03 0,03494552 ! histone methylation GO:0016571 5 5 0,000 5,802E-03 0,03483169 ! DNA methylation GO:0006306 5 5 0,000 5,802E-03 0,0347186 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 5,802E-03 0,03460624 ! T cell lineage commitment GO:0002360 5 5 0,000 5,802E-03 0,03449461 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 5,802E-03 0,03438369 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 5,802E-03 0,03427349 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 5,802E-03 0,03416399 ! intracellular cholesterol transport GO:0032367 5 5 0,000 5,802E-03 0,03405519 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 5,802E-03 0,03394707 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 5,802E-03 0,03383965 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 5,802E-03 0,0337329 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 5,802E-03 0,03362682 ! sterol catabolic process GO:0016127 5 5 0,000 5,802E-03 0,0335214 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 5,802E-03 0,03341665 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 5,802E-03 0,03331255 ! detection of biotic stimulus GO:0009595 5 5 0,000 5,802E-03 0,03320909 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 5,802E-03 0,03310628 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 5,802E-03 0,0330041 ! zymogen activation GO:0031638 5 5 0,000 5,802E-03 0,03290255 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 5,802E-03 0,03280162 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 5,802E-03 0,03270131 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 5,802E-03 0,03260161 ! peptidyl-lysine modification GO:0018205 5 5 0,000 5,802E-03 0,03250252 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 5,802E-03 0,03240402 ! peptidyl-histidine modification GO:0018202 5 5 0,000 5,802E-03 0,03230613 ! nucleosome positioning GO:0016584 5 5 0,000 5,802E-03 0,03220882 ! regulation of isotype switching GO:0045191 5 5 0,000 5,802E-03 0,0321121 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 5,802E-03 0,03201595 ! negative regulation of neurological system process GO:0031645 5 5 0,000 5,802E-03 0,03192038 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 5,802E-03 0,03182538 ! glutathione biosynthetic process GO:0006750 5 5 0,000 5,802E-03 0,03173094 ! NADPH regeneration GO:0006740 5 5 0,000 5,802E-03 0,03163707 GO:0006098|pentose-phosphate shunt, ! positive regulation of epidermis development GO:0045684 5 5 0,000 5,802E-03 0,03154374 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 5,802E-03 0,03145097 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 5,802E-03 0,03135873 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 5,802E-03 0,03126704 ! sarcomere organization GO:0045214 5 5 0,000 5,802E-03 0,03117588 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 5,802E-03 0,03108526 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 5,802E-03 0,03099515 ! negative regulation of glucose transport GO:0010829 5 5 0,000 5,802E-03 0,03090557 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 5,802E-03 0,03081651 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 5,802E-03 0,03072795 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 5,802E-03 0,03063991 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 5,802E-03 0,03055237 ! spleen development GO:0048536 5 5 0,000 5,802E-03 0,03046532 ! male genitalia development GO:0030539 5 5 0,000 5,802E-03 0,03037877 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 5,802E-03 0,03029271 ! quaternary ammonium group transport GO:0015697 5 5 0,000 5,802E-03 0,03020714 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 5,802E-03 0,03012205 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 5,802E-03 0,03003744 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 5,802E-03 0,0299533 ! removal of superoxide radicals GO:0019430 6 5 0,000 5,802E-03 0,02986963 ! myeloid cell homeostasis GO:0002262 5 5 0,000 5,802E-03 0,02978643 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 5,802E-03 0,02970369 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 5,802E-03 0,02962141 ! ATP catabolic process GO:0006200 5 5 0,000 5,802E-03 0,02953958 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 5,802E-03 0,0294582 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 5,802E-03 0,02937728 ! blastocyst formation GO:0001825 5 5 0,000 5,802E-03 0,02929679 ! regulation of fibrinolysis GO:0051917 5 5 0,000 5,802E-03 0,02921674 ! embryonic gut development GO:0048566 5 5 0,000 5,802E-03 0,02913713 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 5,802E-03 0,02905796 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 5,802E-03 0,02897921 ! activation of innate immune response GO:0002218 5 5 0,000 5,802E-03 0,02890089 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 5,802E-03 0,02882299 ! catecholamine transport GO:0051937 5 5 0,000 5,802E-03 0,02874551 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 5,802E-03 0,02866844 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 5,802E-03 0,02859179 ! muscle adaptation GO:0043500 5 5 0,000 5,802E-03 0,02851554 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 5,802E-03 0,0284397 ! embryonic heart tube development GO:0035050 5 5 0,000 5,802E-03 0,02836427 ! cardiac cell differentiation GO:0035051 6 5 0,000 5,802E-03 0,02828923 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 5,802E-03 0,02821459 ! defense response to fungus GO:0050832 5 5 0,000 5,802E-03 0,02814034 ! lysogeny GO:0030069 5 5 0,000 5,802E-03 0,02806648 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 5,802E-03 0,02799301 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 5,802E-03 0,02791992 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 5,802E-03 0,02784721 ! response to nicotine GO:0035094 5 5 0,000 5,802E-03 0,02777488 ! establishment of cell polarity GO:0030010 5 5 0,000 5,802E-03 0,02770292 ! mitochondrion localization GO:0051646 5 5 0,000 5,802E-03 0,02763134 ! nucleus localization GO:0051647 5 5 0,000 5,802E-03 0,02756012 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 5,802E-03 0,02748928 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 6,959E-03 0,03288581 ! axon extension GO:0048675 7 6 0,000 6,959E-03 0,03280171 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 6,959E-03 0,03271803 ! tRNA modification GO:0006400 6 6 0,000 6,959E-03 0,03263478 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 6,959E-03 0,03255195 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 6,959E-03 0,03246954 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 6,959E-03 0,03238754 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 6,959E-03 0,03230596 ! virus-host interaction GO:0019048 6 6 0,000 6,959E-03 0,03222479 ! regulation of S phase GO:0033261 6 6 0,000 6,959E-03 0,03214403 ! myotube differentiation GO:0014902 6 6 0,000 6,959E-03 0,03206367 ! regulation of B cell proliferation GO:0030888 6 6 0,000 6,959E-03 0,03198371 ! bone remodeling GO:0046849 6 6 0,000 6,959E-03 0,03190415 ! N-glycan processing GO:0006491 6 6 0,000 6,959E-03 0,03182498 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,959E-03 0,0317462 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 6,959E-03 0,03166782 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 6,959E-03 0,03158982 ! retina development in camera-type eye GO:0060041 6 6 0,000 6,959E-03 0,0315122 ! RNA methylation GO:0001510 6 6 0,000 6,959E-03 0,03143497 ! cartilage condensation GO:0001502 7 6 0,000 6,959E-03 0,03135811 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 6,959E-03 0,03128163 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 6,959E-03 0,03120552 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 6,959E-03 0,03112977 ! artery development GO:0060840 6 6 0,000 6,959E-03 0,0310544 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 6,959E-03 0,03097939 ! bile acid metabolic process GO:0008206 6 6 0,000 6,959E-03 0,03090474 ! androgen metabolic process GO:0008209 6 6 0,000 6,959E-03 0,03083045 ! estrogen metabolic process GO:0008210 6 6 0,000 6,959E-03 0,03075652 ! limbic system development GO:0021761 7 6 0,000 6,959E-03 0,03068293 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 6,959E-03 0,03060971 ! positive regulation of heart contraction GO:0045823 6 6 0,000 6,959E-03 0,03053683 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 6,959E-03 0,03046429 ! pathogenesis GO:0009405 6 6 0,000 6,959E-03 0,0303921 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 6,959E-03 0,03032025 ! positive regulation of cell growth GO:0030307 6 6 0,000 6,959E-03 0,03024874 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 6,959E-03 0,03017757 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 6,959E-03 0,03010673 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 6,959E-03 0,03003622 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 6,959E-03 0,02996604 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 6,959E-03 0,02989619 ! arginine metabolic process GO:0006525 6 6 0,000 6,959E-03 0,02982667 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 6,959E-03 0,02975746 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 6,959E-03 0,02968858 ! glutamate catabolic process GO:0006538 7 6 0,000 6,959E-03 0,02962002 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 6,959E-03 0,02955177 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 6,959E-03 0,02948383 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 6,959E-03 0,02941621 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 6,959E-03 0,02934889 ! ER overload response GO:0006983 6 6 0,000 6,959E-03 0,02928189 ! V(D)J recombination GO:0033151 6 6 0,000 6,959E-03 0,02921519 ! focal adhesion formation GO:0048041 7 6 0,000 6,959E-03 0,02914879 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,959E-03 0,02908269 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 6,959E-03 0,02901689 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 6,959E-03 0,02895139 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 6,959E-03 0,02888619 ! regulation of heart rate GO:0002027 6 6 0,000 6,959E-03 0,02882127 ! lipid digestion GO:0044241 6 6 0,000 6,959E-03 0,02875665 ! asymmetric protein localization GO:0008105 6 6 0,000 6,959E-03 0,02869232 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 6,959E-03 0,02862827 ! phagocytosis, engulfment GO:0006911 6 6 0,000 6,959E-03 0,02856451 ! Rac protein signal transduction GO:0016601 6 6 0,000 6,959E-03 0,02850104 ! regulation of vascular permeability GO:0043114 6 6 0,000 6,959E-03 0,02843784 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 6,959E-03 0,02837493 ! ruffle organization GO:0031529 6 6 0,000 6,959E-03 0,02831229 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 6,959E-03 0,02824993 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 6,959E-03 0,02818784 ! retinoic acid metabolic process GO:0042573 6 6 0,000 6,959E-03 0,02812602 ! neutral amino acid transport GO:0015804 6 6 0,000 6,959E-03 0,02806448 ! L-amino acid transport GO:0015807 6 6 0,000 6,959E-03 0,0280032 ! bone mineralization GO:0030282 6 6 0,000 6,959E-03 0,02794219 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 6,959E-03 0,02788145 ! negative regulation of ossification GO:0030279 6 6 0,000 6,959E-03 0,02782097 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 6,959E-03 0,02776075 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 6,959E-03 0,02770079 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 6,959E-03 0,02764109 ! purine base biosynthetic process GO:0009113 6 6 0,000 6,959E-03 0,02758165 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 6,959E-03 0,02752246 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 6,959E-03 0,02746353 ! regulation of phagocytosis GO:0050764 6 6 0,000 6,959E-03 0,02740484 ! regulation of organ growth GO:0046620 6 6 0,000 6,959E-03 0,02734641 ! regulation of circadian rhythm GO:0042752 6 6 0,000 6,959E-03 0,02728823 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 6,959E-03 0,02723029 ! response to dsRNA GO:0043331 6 6 0,000 6,959E-03 0,0271726 ! DNA unwinding during replication GO:0006268 6 6 0,000 6,959E-03 0,02711515 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 6,959E-03 0,02705795 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 6,959E-03 0,02700098 ! genitalia development GO:0048806 6 6 0,000 6,959E-03 0,02694426 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 6,959E-03 0,02688777 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 6,959E-03 0,02683152 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 6,959E-03 0,0267755 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 6,959E-03 0,02671972 ! multicellular organismal aging GO:0010259 6 6 0,000 6,959E-03 0,02666417 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 6,959E-03 0,02660885 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 6,959E-03 0,02655376 ! erythrocyte development GO:0048821 6 6 0,000 6,959E-03 0,0264989 ! renal water homeostasis GO:0003091 6 6 0,000 6,959E-03 0,02644426 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 6,959E-03 0,02638985 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 6,959E-03 0,02633566 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 6,959E-03 0,02628169 ! ribosome assembly GO:0042255 6 6 0,000 6,959E-03 0,02622795 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 6,959E-03 0,02617442 ! diencephalon development GO:0021536 6 6 0,000 6,959E-03 0,02612111 ! fucose catabolic process GO:0019317 6 6 0,000 6,959E-03 0,02606802 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 6,959E-03 0,02601515 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 6,959E-03 0,02596248 ! regulation of lipid transport GO:0032368 6 6 0,000 6,959E-03 0,02591003 ! regulation of cell division GO:0051302 6 6 0,000 6,959E-03 0,0258578 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 6,959E-03 0,02580577 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 6,959E-03 0,02575395 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 6,959E-03 0,02570234 ! salivary gland morphogenesis GO:0007435 6 6 0,000 6,959E-03 0,02565093 ! neuroblast proliferation GO:0007405 6 6 0,000 6,959E-03 0,02559973 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 6,959E-03 0,02554874 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 6,959E-03 0,02549795 ! regulation of glucose transport GO:0010827 6 6 0,000 6,959E-03 0,02544735 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 6,959E-03 0,02539696 ! methionine biosynthetic process GO:0009086 6 6 0,000 6,959E-03 0,02534677 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 6,959E-03 0,02529678 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 6,959E-03 0,02524698 ! lymph node development GO:0048535 6 6 0,000 6,959E-03 0,02519738 ! organic cation transport GO:0015695 6 6 0,000 6,959E-03 0,02514797 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 6,959E-03 0,02509876 ! regulation of RNA splicing GO:0043484 6 6 0,000 6,959E-03 0,02504974 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 6,959E-03 0,02500091 ! sperm-egg recognition GO:0035036 7 6 0,000 6,959E-03 0,02495227 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 6,959E-03 0,02490382 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 6,959E-03 0,02485556 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 6,959E-03 0,02480748 ! alditol metabolic process GO:0019400 6 6 0,000 6,959E-03 0,02475959 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 6,959E-03 0,02471188 ! regulation of amino acid transport GO:0051955 6 6 0,000 6,959E-03 0,02466436 ! maternal placenta development GO:0001893 6 6 0,000 6,959E-03 0,02461702 ! regulation of embryonic development GO:0045995 6 6 0,000 6,959E-03 0,02456986 ! negative regulation of immune effector process GO:0002698 6 6 0,000 6,959E-03 0,02452288 ! localization within membrane GO:0051668 6 6 0,000 6,959E-03 0,02447608 ! respiratory burst GO:0045730 7 7 0,000 8,115E-03 0,02848654 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 8,115E-03 0,02843238 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 8,115E-03 0,02837843 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 8,115E-03 0,02832469 ! positive regulation of blood pressure GO:0045777 7 7 0,000 8,115E-03 0,02827114 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 8,115E-03 0,0282178 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 8,115E-03 0,02816466 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 8,115E-03 0,02811172 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 8,115E-03 0,02805898 ! cellular protein complex disassembly GO:0043624 8 7 0,000 8,115E-03 0,02800643 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 8,115E-03 0,02795408 ! gene silencing by RNA GO:0031047 7 7 0,000 8,115E-03 0,02790193 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 8,115E-03 0,02784997 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 8,115E-03 0,0277982 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 8,115E-03 0,02774663 ! keratinocyte proliferation GO:0043616 7 7 0,000 8,115E-03 0,02769525 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 8,115E-03 0,02764406 ! visual behavior GO:0007632 7 7 0,000 8,115E-03 0,02759305 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 8,115E-03 0,02754224 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 8,115E-03 0,02749161 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 8,115E-03 0,02744116 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 8,115E-03 0,02739091 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 8,115E-03 0,02734083 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 8,115E-03 0,02729094 ! endothelial cell differentiation GO:0045446 7 7 0,000 8,115E-03 0,02724123 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 8,115E-03 0,0271917 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 8,115E-03 0,02714235 ! digestive system development GO:0055123 7 7 0,000 8,115E-03 0,02709318 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of exit from mitosis GO:0007096 7 7 0,000 8,115E-03 0,02704418 ! protein targeting to ER GO:0045047 8 7 0,000 8,115E-03 0,02699537 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 8,115E-03 0,02694673 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 8,115E-03 0,02689826 ! endoderm development GO:0007492 7 7 0,000 8,115E-03 0,02684997 ! regulation of defense response to virus GO:0050688 7 7 0,000 8,115E-03 0,02680185 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 8,115E-03 0,02675391 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 8,115E-03 0,02670613 ! response to hexose stimulus GO:0009746 7 7 0,000 8,115E-03 0,02665853 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 8,115E-03 0,02661109 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 8,115E-03 0,02656383 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 8,115E-03 0,02651673 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 8,115E-03 0,0264698 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 8,115E-03 0,02642303 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 8,115E-03 0,02637643 ! complement activation, alternative pathway GO:0006957 7 7 0,000 8,115E-03 0,02632999 ! arachidonic acid secretion GO:0050482 7 7 0,000 8,115E-03 0,02628372 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 8,115E-03 0,0262376 ! response to X-ray GO:0010165 7 7 0,000 8,115E-03 0,02619165 ! regulation of intracellular pH GO:0051453 7 7 0,000 8,115E-03 0,02614586 ! UV protection GO:0009650 7 7 0,000 8,115E-03 0,02610023 ! DNA integration GO:0015074 7 7 0,000 8,115E-03 0,02605476 ! myofibril assembly GO:0030239 7 7 0,000 8,115E-03 0,02600945 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 8,115E-03 0,0259643 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 8,115E-03 0,0259193 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 8,115E-03 0,02587445 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 8,115E-03 0,02582977 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 8,115E-03 0,02578523 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 8,115E-03 0,02574085 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 8,115E-03 0,02569662 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 8,115E-03 0,02565255 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 8,115E-03 0,02560862 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 8,115E-03 0,02556484 ! axon cargo transport GO:0008088 7 7 0,000 8,115E-03 0,02552122 ! eating behavior GO:0042755 7 7 0,000 8,115E-03 0,02547774 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 8,115E-03 0,02543441 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 8,115E-03 0,02539123 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 8,115E-03 0,02534819 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 8,115E-03 0,0253053 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 8,115E-03 0,02526256 ! cranial nerve development GO:0021545 7 7 0,000 8,115E-03 0,02521996 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 8,115E-03 0,0251775 ! leukocyte activation during immune response GO:0002366 7 7 0,000 8,115E-03 0,02513518 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 8,115E-03 0,02509301 ! autonomic nervous system development GO:0048483 7 7 0,000 8,115E-03 0,02505098 ! intracellular lipid transport GO:0032365 7 7 0,000 8,115E-03 0,02500909 ! detection of chemical stimulus GO:0009593 8 7 0,000 8,115E-03 0,02496734 ! platelet activation GO:0030168 8 7 0,000 8,115E-03 0,02492572 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 8,115E-03 0,02488425 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 8,115E-03 0,02484291 ! natural killer cell activation GO:0030101 7 7 0,000 8,115E-03 0,02480172 ! response to gamma radiation GO:0010332 8 7 0,000 8,115E-03 0,02476065 ! NADP metabolic process GO:0006739 7 7 0,000 8,115E-03 0,02471973 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 8,115E-03 0,02467893 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 8,115E-03 0,02463828 ! ubiquinone metabolic process GO:0006743 7 7 0,000 8,115E-03 0,02459775 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 8,115E-03 0,02455736 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 8,115E-03 0,02451711 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 8,115E-03 0,02447698 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 8,115E-03 0,02443698 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 8,115E-03 0,02439712 ! regulation of ATPase activity GO:0043462 7 7 0,000 8,115E-03 0,02435738 ! cell-cell recognition GO:0009988 8 7 0,000 8,115E-03 0,02431778 ! hormone catabolic process GO:0042447 7 7 0,000 8,115E-03 0,0242783 ! dopamine metabolic process GO:0042417 7 7 0,000 8,115E-03 0,02423895 ! cAMP biosynthetic process GO:0006171 7 7 0,000 8,115E-03 0,02419973 ! oxygen transport GO:0015671 7 7 0,000 8,115E-03 0,02416064 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 8,115E-03 0,02412167 ! regulation of mRNA stability GO:0043488 7 7 0,000 8,115E-03 0,02408282 ! biogenic amine catabolic process GO:0042402 7 7 0,000 8,115E-03 0,02404411 ! regulation of axon extension GO:0030516 7 7 0,000 8,115E-03 0,02400551 ! cell killing GO:0001906 7 7 0,000 8,115E-03 0,02396704 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 8,115E-03 0,02392869 ! adult feeding behavior GO:0008343 7 7 0,000 8,115E-03 0,02389047 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 8,115E-03 0,02385237 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 8,115E-03 0,02381439 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 8,115E-03 0,02377653 ! negative regulation of T cell activation GO:0050868 7 7 0,000 8,115E-03 0,02373878 ! response to cold GO:0009409 7 7 0,000 8,115E-03 0,02370116 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 9,269E-03 0,02703043 ! negative regulation of muscle development GO:0048635 8 8 0,000 9,269E-03 0,02698773 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 9,269E-03 0,02694516 ! positive regulation of translation GO:0045727 8 8 0,000 9,269E-03 0,02690273 ! positive regulation of cell killing GO:0031343 8 8 0,000 9,269E-03 0,02686043 ! superoxide anion generation GO:0042554 8 8 0,000 9,269E-03 0,02681826 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 9,269E-03 0,02677623 ! cGMP metabolic process GO:0046068 8 8 0,000 9,269E-03 0,02673432 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 8 8 0,000 9,269E-03 0,02669255 ! dicarboxylic acid transport GO:0006835 8 8 0,000 9,269E-03 0,02665091 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 9,269E-03 0,0266094 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 9,269E-03 0,02656801 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 9,269E-03 0,02652676 ! zinc ion transport GO:0006829 8 8 0,000 9,269E-03 0,02648563 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 9,269E-03 0,02644463 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 9,269E-03 0,02640376 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 9,269E-03 0,02636301 ! cardiac muscle contraction GO:0060048 8 8 0,000 9,269E-03 0,02632239 ! lipid localization GO:0010876 8 8 0,000 9,269E-03 0,0262819 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 9,269E-03 0,02624152 ! response to cAMP GO:0051591 8 8 0,000 9,269E-03 0,02620128 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 9,269E-03 0,02616115 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 9,269E-03 0,02612115 ! negative regulation of ion transport GO:0043271 8 8 0,000 9,269E-03 0,02608127 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 9,269E-03 0,02604151 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 9,269E-03 0,02600188 ! sensory perception of taste GO:0050909 8 8 0,000 9,269E-03 0,02596236 ! organelle fusion GO:0048284 8 8 0,000 9,269E-03 0,02592296 ! pancreas development GO:0031016 8 8 0,000 9,269E-03 0,02588369 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 9,269E-03 0,02584453 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 9,269E-03 0,02580549 ! negative regulation of proteolysis GO:0045861 8 8 0,000 9,269E-03 0,02576656 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 9,269E-03 0,02572776 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 9,269E-03 0,02568907 ! sperm motility GO:0030317 8 8 0,000 9,269E-03 0,0256505 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 9,269E-03 0,02561204 ! DNA duplex unwinding GO:0032508 8 8 0,000 9,269E-03 0,0255737 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 9,269E-03 0,02553547 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 9,269E-03 0,02549736 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 9,269E-03 0,02545936 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 9,269E-03 0,02542148 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 9,269E-03 0,0253837 ! Golgi organization GO:0007030 8 8 0,000 9,269E-03 0,02534604 ! cell-cell junction assembly GO:0007043 8 8 0,000 9,269E-03 0,02530849 ! regulation of stress fiber formation GO:0051492 9 8 0,000 9,269E-03 0,02527105 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 9,269E-03 0,02523373 ! fructose metabolic process GO:0006000 8 8 0,000 9,269E-03 0,02519651 ! mannose metabolic process GO:0006013 9 8 0,000 9,269E-03 0,0251594 ! NAD metabolic process GO:0019674 8 8 0,000 9,269E-03 0,0251224 ! sex determination GO:0007530 8 8 0,000 9,269E-03 0,02508551 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 9,269E-03 0,02504873 ! plasma membrane fusion GO:0045026 8 8 0,000 9,269E-03 0,02501205 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 9,269E-03 0,02497549 ! response to fungus GO:0009620 8 8 0,000 9,269E-03 0,02493903 ! stem cell differentiation GO:0048863 8 8 0,000 9,269E-03 0,02490267 ! alpha-beta T cell activation GO:0046631 8 8 0,000 9,269E-03 0,02486642 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 9,269E-03 0,02483028 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 9,269E-03 0,02479424 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 9,269E-03 0,02475831 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 9,269E-03 0,02472248 ! regulation of vasodilation GO:0042312 8 8 0,000 9,269E-03 0,02468675 ! vasoconstriction GO:0042310 8 8 0,000 9,269E-03 0,02465113 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 9,269E-03 0,02461561 ! muscle cell development GO:0055001 8 8 0,000 9,269E-03 0,02458019 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 9,269E-03 0,02454487 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 9,269E-03 0,02450966 ! sensory perception of pain GO:0019233 8 8 0,000 9,269E-03 0,02447454 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 9,269E-03 0,02443953 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 9,269E-03 0,02440462 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 9,269E-03 0,0243698 ! chromatin silencing GO:0006342 8 8 0,000 9,269E-03 0,02433509 ! tissue regeneration GO:0042246 8 8 0,000 9,269E-03 0,02430047 ! salivary gland development GO:0007431 8 8 0,000 9,269E-03 0,02426596 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 9,269E-03 0,02423154 ! T cell homeostasis GO:0043029 8 8 0,000 9,269E-03 0,02419721 ! peptide biosynthetic process GO:0043043 9 8 0,000 9,269E-03 0,02416299 ! peptidyl-serine modification GO:0018209 8 8 0,000 9,269E-03 0,02412886 ! water homeostasis GO:0030104 8 8 0,000 9,269E-03 0,02409483 ! cofactor transport GO:0051181 8 8 0,000 9,269E-03 0,02406089 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 9,269E-03 0,02402705 ! acid secretion GO:0046717 8 8 0,000 9,269E-03 0,0239933 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 9,269E-03 0,02395965 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 9,269E-03 0,0239261 ! protein-chromophore linkage GO:0018298 9 8 0,000 9,269E-03 0,02389263 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 9,269E-03 0,02385926 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 9,269E-03 0,02382599 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 9,269E-03 0,0237928 ! regulation of RNA stability GO:0043487 8 8 0,000 9,269E-03 0,02375971 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 9,269E-03 0,02372671 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 9,269E-03 0,0236938 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 9,269E-03 0,02366099 ! regulation of organic acid transport GO:0032890 8 8 0,000 9,269E-03 0,02362826 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 9,269E-03 0,02359562 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 9,269E-03 0,02356308 ! regulation of multi-organism process GO:0043900 8 8 0,000 9,269E-03 0,02353062 ! positive regulation of amine transport GO:0051954 8 8 0,000 9,269E-03 0,02349826 ! peptide hormone secretion GO:0030072 8 8 0,000 9,269E-03 0,02346598 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 9,269E-03 0,02343379 ! actin filament polymerization GO:0030041 9 8 0,000 9,269E-03 0,02340169 ! peptide hormone processing GO:0016486 8 8 0,000 9,269E-03 0,02336967 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 9,269E-03 0,02333775 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 9,269E-03 0,02330591 ! lactation GO:0007595 10 9 0,000 0,01042261 0,02617011 ! embryonic pattern specification GO:0009880 10 9 0,000 0,01042261 0,02613451 ! positive regulation of cell size GO:0045793 9 9 0,000 0,01042261 0,026099 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,01042261 0,02606359 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,01042261 0,02602827 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,01042261 0,02599305 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,01042261 0,02595792 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,01042261 0,02592289 ! viral genome replication GO:0019079 9 9 0,000 0,01042261 0,02588796 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,01042261 0,02585311 ! copper ion transport GO:0006825 9 9 0,000 0,01042261 0,02581836 ! lipid phosphorylation GO:0046834 9 9 0,000 0,01042261 0,02578371 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,01042261 0,02574915 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,01042261 0,02571468 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,01042261 0,0256803 ! RNA polyadenylation GO:0043631 9 9 0,000 0,01042261 0,02564601 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,01042261 0,02561182 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,01042261 0,02557771 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,01042261 0,0255437 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,01042261 0,02550978 ! phospholipid efflux GO:0033700 9 9 0,000 0,01042261 0,02547595 ! response to alkaloid GO:0043279 10 9 0,000 0,01042261 0,0254422 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,01042261 0,02540855 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,01042261 0,02537498 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,01042261 0,02534151 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,01042261 0,02530812 ! response to ethanol GO:0045471 9 9 0,000 0,01042261 0,02527482 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,01042261 0,02524161 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,01042261 0,02520848 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,01042261 0,02517544 ! methionine metabolic process GO:0006555 9 9 0,000 0,01042261 0,02514249 ! glutamine metabolic process GO:0006541 9 9 0,000 0,01042261 0,02510962 ! cerebral cortex development GO:0021987 9 9 0,000 0,01042261 0,02507684 ! response to osmotic stress GO:0006970 9 9 0,000 0,01042261 0,02504415 ! pigmentation during development GO:0048066 9 9 0,000 0,01042261 0,02501154 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,01042261 0,02497902 ! central nervous system neuron development GO:0021954 10 9 0,000 0,01042261 0,02494658 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,01042261 0,02491422 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,01042261 0,02488195 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,01042261 0,02484976 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,01042261 0,02481765 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,01042261 0,02478563 ! L-glutamate transport GO:0015813 9 9 0,000 0,01042261 0,02475369 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,01042261 0,02472183 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,01042261 0,02469006 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,01042261 0,02465836 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,01042261 0,02462675 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,01042261 0,02459522 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,01042261 0,02456376 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,01042261 0,02453239 ! DNA replication initiation GO:0006270 9 9 0,000 0,01042261 0,0245011 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,01042261 0,02446989 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,01042261 0,02443876 ! regulation of cellular pH GO:0030641 9 9 0,000 0,01042261 0,0244077 ! histone acetylation GO:0016573 9 9 0,000 0,01042261 0,02437673 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,01042261 0,02434583 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,01042261 0,02431502 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,01042261 0,02428428 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,01042261 0,02425361 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,01042261 0,02422303 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,01042261 0,02419252 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,01042261 0,02416209 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,01042261 0,02413174 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,01042261 0,02410146 ! collagen catabolic process GO:0030574 9 9 0,000 0,01042261 0,02407126 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,01042261 0,02404113 ! purine base metabolic process GO:0006144 9 9 0,000 0,01042261 0,02401108 ! gas transport GO:0015669 9 9 0,000 0,01042261 0,0239811 ! cholesterol efflux GO:0033344 9 9 0,000 0,01042261 0,0239512 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,01042261 0,02392137 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,01042261 0,02389162 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,01042261 0,02386194 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,01042261 0,02383234 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,01042261 0,0238028 ! defense response to virus GO:0051607 9 9 0,000 0,01042261 0,02377335 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,01042261 0,02374396 ! actin filament-based movement GO:0030048 9 9 0,000 0,01042261 0,02371465 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,01042261 0,0236854 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01157478 0,02627134 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,01157478 0,02623903 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01157478 0,02620679 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01157478 0,02617464 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01157478 0,02614256 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01157478 0,02611056 ! neuron maturation GO:0042551 10 10 0,000 0,01157478 0,02607864 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01157478 0,0260468 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01157478 0,02601503 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01157478 0,02598335 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01157478 0,02595174 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01157478 0,0259202 ! hormone secretion GO:0046879 10 10 0,000 0,01157478 0,02588875 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01157478 0,02585737 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01157478 0,02582606 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,01157478 0,02579483 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01157478 0,02576368 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01157478 0,0257326 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01157478 0,0257016 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01157478 0,02567067 ! glial cell development GO:0021782 10 10 0,000 0,01157478 0,02563982 ! phototransduction GO:0007602 11 10 0,000 0,01157478 0,02560904 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01157478 0,02557833 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01157478 0,0255477 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,01157478 0,02551714 ! fat cell differentiation GO:0045444 10 10 0,000 0,01157478 0,02548665 ! myoblast differentiation GO:0045445 10 10 0,000 0,01157478 0,02545624 ! centrosome cycle GO:0007098 10 10 0,000 0,01157478 0,0254259 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01157478 0,02539563 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01157478 0,02536543 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01157478 0,02533531 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01157478 0,02530525 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01157478 0,02527527 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,01157478 0,02524536 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01157478 0,02521552 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01157478 0,02518575 ! plasma membrane organization GO:0007009 10 10 0,000 0,01157478 0,02515605 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01157478 0,02512642 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01157478 0,02509686 ! lysosomal transport GO:0007041 10 10 0,000 0,01157478 0,02506737 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01157478 0,02503794 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01157478 0,02500859 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,01157478 0,02497931 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,01157478 0,02495009 ! exocrine system development GO:0035272 10 10 0,000 0,01157478 0,02492094 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01157478 0,02489186 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01157478 0,02486285 ! embryo implantation GO:0007566 11 10 0,000 0,01157478 0,02483391 ! regulation of protein binding GO:0043393 11 10 0,000 0,01157478 0,02480503 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01157478 0,02477622 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01157478 0,02474748 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,01157478 0,0247188 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01157478 0,02469019 ! protein export from nucleus GO:0006611 10 10 0,000 0,01157478 0,02466165 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01157478 0,02463317 ! cytolysis GO:0019835 10 10 0,000 0,01157478 0,02460476 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01157478 0,02457641 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01157478 0,02454813 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01157478 0,02451992 ! histone deacetylation GO:0016575 10 10 0,000 0,01157478 0,02449177 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01157478 0,02446368 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01157478 0,02443566 ! gland morphogenesis GO:0022612 10 10 0,000 0,01157478 0,0244077 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01157478 0,0243798 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01157478 0,02435197 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01157478 0,02432421 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01157478 0,0242965 ! regulation of epidermis development GO:0045682 10 10 0,000 0,01157478 0,02426886 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01157478 0,02424128 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,01157478 0,02421377 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01157478 0,02418631 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01157478 0,02415892 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01157478 0,02413159 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01157478 0,02410433 ! nerve development GO:0021675 10 10 0,000 0,01157478 0,02407712 ! gut development GO:0048565 10 10 0,000 0,01157478 0,02404998 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01157478 0,02402289 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,01157478 0,02399587 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01157478 0,02396891 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01157478 0,02394201 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01157478 0,02391517 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01157478 0,02388839 ! protein stabilization GO:0050821 10 10 0,000 0,01157478 0,02386166 ! protein secretion GO:0009306 11 11 0,000 0,01272579 0,02620517 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01272579 0,02617593 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01272579 0,02614674 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01272579 0,02611763 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01272579 0,02608858 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01272579 0,02605959 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,01272579 0,02603067 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01272579 0,02600181 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01272579 0,02597301 ! skin development GO:0043588 11 11 0,000 0,01272579 0,02594428 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,01272579 0,02591561 ! signal complex assembly GO:0007172 11 11 0,000 0,01272579 0,02588701 ! microtubule-based transport GO:0010970 11 11 0,000 0,01272579 0,02585847 ! endothelial cell migration GO:0043542 11 11 0,000 0,01272579 0,02582999 ! peroxisomal transport GO:0043574 11 11 0,000 0,01272579 0,02580157 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01272579 0,02577322 GO:0008213|protein amino acid alkylation, ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01272579 0,02574493 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01272579 0,0257167 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01272579 0,02568853 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01272579 0,02566043 ! T cell proliferation GO:0042098 11 11 0,000 0,01272579 0,02563238 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01272579 0,0256044 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01272579 0,02557648 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,01272579 0,02554862 ! spinal cord development GO:0021510 11 11 0,000 0,01272579 0,02552082 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01272579 0,02549308 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01272579 0,0254654 ! cellular response to starvation GO:0009267 11 11 0,000 0,01272579 0,02543778 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01272579 0,02541022 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,01272579 0,02538272 ! digestive system process GO:0022600 11 11 0,000 0,01272579 0,02535528 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01272579 0,02532789 ! fucose metabolic process GO:0006004 11 11 0,000 0,01272579 0,02530057 ! membrane budding GO:0006900 11 11 0,000 0,01272579 0,02527331 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,01272579 0,0252461 ! monoamine transport GO:0015844 11 11 0,000 0,01272579 0,02521896 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01272579 0,02519187 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01272579 0,02516484 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01272579 0,02513787 ! body fluid secretion GO:0007589 11 11 0,000 0,01272579 0,02511095 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01272579 0,0250841 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,01272579 0,0250573 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01272579 0,02503055 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01272579 0,02500387 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01272579 0,02497724 ! membrane depolarization GO:0051899 11 11 0,000 0,01272579 0,02495067 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01272579 0,02492415 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01272579 0,0248977 ! oogenesis GO:0048477 11 11 0,000 0,01272579 0,02487129 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01272579 0,02484495 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01272579 0,02481866 ! vitamin transport GO:0051180 11 11 0,000 0,01272579 0,02479242 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01272579 0,02476624 ! hindbrain development GO:0030902 11 11 0,000 0,01272579 0,02474012 ! steroid catabolic process GO:0006706 11 11 0,000 0,01272579 0,02471405 ! endocrine process GO:0050886 11 11 0,000 0,01272579 0,02468803 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01272579 0,02466207 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01272579 0,02463617 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01272579 0,02461031 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,01272579 0,02458452 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01272579 0,02455877 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,01387562 0,02674976 ! translational initiation GO:0006413 12 12 0,000 0,01387562 0,02672181 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,01387562 0,02669391 ! initiation of viral infection GO:0019059 12 12 0,000 0,01387562 0,02666608 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,01387562 0,0266383 ! iron ion transport GO:0006826 13 12 0,000 0,01387562 0,02661058 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,01387562 0,02658292 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,01387562 0,02655532 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,01387562 0,02652777 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,01387562 0,02650028 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,01387562 0,02647285 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,01387562 0,02644547 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,01387562 0,02641815 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,01387562 0,02639089 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,01387562 0,02636368 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,01387562 0,02633653 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,01387562 0,02630943 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,01387562 0,02628239 ! actomyosin structure organization GO:0031032 12 12 0,000 0,01387562 0,02625541 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,01387562 0,02622848 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,01387562 0,02620161 ! retinoid metabolic process GO:0001523 12 12 0,000 0,01387562 0,02617479 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,01387562 0,02614803 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,01387562 0,02612132 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,01387562 0,02609466 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,01387562 0,02606806 ! acute-phase response GO:0006953 12 12 0,000 0,01387562 0,02604152 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01387562 0,02601502 ! vacuolar transport GO:0007034 12 12 0,000 0,01387562 0,02598859 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,01387562 0,0259622 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,01387562 0,02593587 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,01387562 0,02590959 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,01387562 0,02588337 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,01387562 0,0258572 ! male gonad development GO:0008584 12 12 0,000 0,01387562 0,02583108 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,01387562 0,02580501 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,01387562 0,025779 ! renal system process GO:0003014 12 12 0,000 0,01387562 0,02575304 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,01387562 0,02572713 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,01387562 0,02570128 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,01387562 0,02567547 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,01387562 0,02564972 ! pallium development GO:0021543 13 12 0,000 0,01387562 0,02562402 ! cell fate determination GO:0001709 12 12 0,000 0,01387562 0,02559837 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,01387562 0,02557277 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,01387562 0,02554722 ! somitogenesis GO:0001756 13 12 0,000 0,01387562 0,02552173 ! G1 phase GO:0051318 13 12 0,000 0,01387562 0,02549628 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,01387562 0,02547089 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,01387562 0,02544554 ! detection of light stimulus GO:0009583 13 12 0,000 0,01387562 0,02542025 ! synaptogenesis GO:0007416 12 12 0,000 0,01387562 0,025395 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,01387562 0,02536981 ! hormone transport GO:0009914 12 12 0,000 0,01387562 0,02534467 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,01387562 0,02531957 ! heme biosynthetic process GO:0006783 12 12 0,000 0,01387562 0,02529453 ! spermatid differentiation GO:0048515 13 12 0,000 0,01387562 0,02526954 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,01387562 0,02524459 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,01387562 0,02521969 ! neural tube closure GO:0001843 13 12 0,000 0,01387562 0,02519485 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,01387562 0,02517005 ! negative regulation of translation GO:0017148 12 12 0,000 0,01387562 0,0251453 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,01387562 0,0251206 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,01387562 0,02509595 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,01502428 0,02714681 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,01502428 0,02712022 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,01502428 0,02709369 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,01502428 0,0270672 ! phenol metabolic process GO:0018958 13 13 0,000 0,01502428 0,02704077 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,01502428 0,02701439 ! gluconeogenesis GO:0006094 13 13 0,000 0,01502428 0,02698806 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,01502428 0,02696178 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,01502428 0,02693555 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,01502428 0,02690938 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,01502428 0,02688325 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,01502428 0,02685718 ! regeneration GO:0031099 13 13 0,000 0,01502428 0,02683115 ! keratinization GO:0031424 13 13 0,000 0,01502428 0,02680518 ! post-embryonic development GO:0009791 14 13 0,000 0,01502428 0,02677925 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,01502428 0,02675338 ! patterning of blood vessels GO:0001569 13 13 0,000 0,01502428 0,02672756 ! vasculogenesis GO:0001570 13 13 0,000 0,01502428 0,02670178 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,01502428 0,02667606 ! regulation of innate immune response GO:0045088 13 13 0,000 0,01502428 0,02665038 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,01502428 0,02662476 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,01502428 0,02659918 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,01502428 0,02657366 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,01502428 0,02654818 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,01502428 0,02652275 ! autophagy GO:0006914 13 13 0,000 0,01502428 0,02649737 ! receptor metabolic process GO:0043112 14 13 0,000 0,01502428 0,02647204 ! actin filament bundle formation GO:0051017 13 13 0,000 0,01502428 0,02644675 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,01502428 0,02642152 ! cell aging GO:0007569 13 13 0,000 0,01502428 0,02639633 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,01502428 0,02637119 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,01502428 0,0263461 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,01502428 0,02632105 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,01502428 0,02629606 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,01502428 0,02627111 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,01502428 0,02624621 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,01502428 0,02622135 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,01502428 0,02619655 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,01502428 0,02617179 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,01502428 0,02614707 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,01502428 0,02612241 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,01502428 0,02609778 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,01502428 0,02607321 ! vasodilation GO:0042311 14 13 0,000 0,01502428 0,02604868 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,01502428 0,0260242 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,01502428 0,02599976 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,01502428 0,02597537 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,01502428 0,02595103 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,01502428 0,02592673 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,01502428 0,02590248 ! immunoglobulin production GO:0002377 13 13 0,000 0,01502428 0,02587827 GO:0002440|production of molecular mediator of immune response, ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,01502428 0,02585411 ! cell-cell junction organization GO:0045216 13 13 0,000 0,01502428 0,02582999 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,01502428 0,02580592 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,01502428 0,02578189 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,01502428 0,02575791 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,01502428 0,02573397 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,01502428 0,02571007 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,01502428 0,02568622 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,01502428 0,02566242 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,01502428 0,02563866 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,01502428 0,02561494 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,01502428 0,02559127 ! blastocyst development GO:0001824 13 13 0,000 0,01502428 0,02556764 ! telomere organization GO:0032200 13 13 0,000 0,01502428 0,02554405 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,01502428 0,02552051 ! regulation of amine transport GO:0051952 13 13 0,000 0,01502428 0,02549701 ! tissue homeostasis GO:0001894 13 13 0,000 0,01502428 0,02547355 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,01502428 0,02545014 ! protein tetramerization GO:0051262 13 13 0,000 0,01502428 0,02542677 ! neuron fate commitment GO:0048663 14 14 0,000 0,01617177 0,02734364 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,01617177 0,02731858 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,01617177 0,02729356 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,01617177 0,02726859 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,01617177 0,02724367 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,01617177 0,02721879 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,01617177 0,02719395 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,01617177 0,02716916 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,01617177 0,02714442 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,01617177 0,02711972 ! vesicle docking GO:0048278 14 14 0,000 0,01617177 0,02709506 ! superoxide metabolic process GO:0006801 15 14 0,000 0,01617177 0,02707046 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,01617177 0,02704589 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,01617177 0,02702137 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,01617177 0,02699689 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,01617177 0,02697246 ! hair cycle GO:0042633 14 14 0,000 0,01617177 0,02694808 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,01617177 0,02692373 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,01617177 0,02689943 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,01617177 0,02687518 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,01617177 0,02685097 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,01617177 0,0268268 ! lysosome organization GO:0007040 14 14 0,000 0,01617177 0,02680267 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,01617177 0,02677859 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,01617177 0,02675455 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,01617177 0,02673056 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,01617177 0,02670661 ! primary neural tube formation GO:0014020 15 14 0,000 0,01617177 0,0266827 ! peptide cross-linking GO:0018149 14 14 0,000 0,01617177 0,02665883 ! regulation of behavior GO:0050795 14 14 0,000 0,01617177 0,02663501 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,01617177 0,02661122 ! base-excision repair GO:0006284 14 14 0,000 0,01617177 0,02658749 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,01617177 0,02656379 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,01617177 0,02654013 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,01617177 0,02651652 ! formation of primary germ layer GO:0001704 14 14 0,000 0,01617177 0,02649295 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,01617177 0,02646942 ! collagen fibril organization GO:0030199 14 14 0,000 0,01617177 0,02644594 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,01617177 0,02642249 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,01617177 0,02639909 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,01617177 0,02637573 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,01617177 0,02635241 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,01617177 0,02632913 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,01617177 0,02630589 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,01617177 0,02628269 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,01617177 0,02625953 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,01617177 0,02623642 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,01731809 0,02807145 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,01731809 0,02804678 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,01731809 0,02802216 ! positive regulation of ossification GO:0045778 15 15 0,000 0,01731809 0,02799758 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,01731809 0,02797304 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,01731809 0,02794854 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,01731809 0,02792409 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,01731809 0,02789968 ! response to vitamin GO:0033273 15 15 0,000 0,01731809 0,02787532 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,01731809 0,02785099 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,01731809 0,02782671 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,01731809 0,02780247 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,01731809 0,02777827 ! ovarian follicle development GO:0001541 15 15 0,000 0,01731809 0,02775412 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,01731809 0,02773001 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,01731809 0,02770593 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,01731809 0,02768191 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,01731809 0,02765792 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,01731809 0,02763397 ! heme metabolic process GO:0042168 15 15 0,000 0,01731809 0,02761007 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,01731809 0,0275862 ! chromosome condensation GO:0030261 15 15 0,000 0,01731809 0,02756238 ! response to starvation GO:0042594 15 15 0,000 0,01731809 0,0275386 ! response to ionizing radiation GO:0010212 16 15 0,000 0,01731809 0,02751486 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,01731809 0,02749116 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,01731809 0,0274675 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,01731809 0,02744388 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,01731809 0,02742031 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,01731809 0,02739677 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,01731809 0,02737327 ! phospholipid transport GO:0015914 15 15 0,000 0,01731809 0,02734982 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,01731809 0,0273264 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,01731809 0,02730303 ! glutathione metabolic process GO:0006749 16 15 0,000 0,01731809 0,02727969 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,01731809 0,02725639 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,01731809 0,02723314 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,01731809 0,02720992 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,01731809 0,02718674 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,01731809 0,02716361 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,01731809 0,02714051 ! protein homooligomerization GO:0051260 15 15 0,000 0,01731809 0,02711745 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,01731809 0,02709443 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,01846324 0,02886153 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,01846324 0,02883708 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,01846324 0,02881266 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,01846324 0,02878828 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,01846324 0,02876395 ! learning GO:0007612 16 16 0,000 0,01846324 0,02873965 ! circadian rhythm GO:0007623 16 16 0,000 0,01846324 0,0287154 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,01846324 0,02869119 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,01846324 0,02866702 ! vacuole organization GO:0007033 16 16 0,000 0,01846324 0,02864289 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,01846324 0,0286188 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,01846324 0,02859475 ! vesicle targeting GO:0006903 17 16 0,000 0,01846324 0,02857074 ! segmentation GO:0035282 17 16 0,000 0,01846324 0,02854677 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,01846324 0,02852284 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,01846324 0,02849895 ! positive regulation of cell development GO:0010720 16 16 0,000 0,01846324 0,0284751 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,01846324 0,02845129 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,01846324 0,02842753 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,01846324 0,0284038 ! pentose metabolic process GO:0019321 16 16 0,000 0,01846324 0,02838011 ! fatty acid transport GO:0015908 16 16 0,000 0,01846324 0,02835646 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,01846324 0,02833285 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,01846324 0,02830928 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,01846324 0,02828574 ! cofactor catabolic process GO:0051187 16 16 0,000 0,01846324 0,02826225 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,01846324 0,0282388 ! polyol metabolic process GO:0019751 16 16 0,000 0,01846324 0,02821538 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,01846324 0,028192 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,01846324 0,02816867 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,01846324 0,02814537 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,01846324 0,02812211 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,01846324 0,02809888 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,01846324 0,0280757 ! regulation of coagulation GO:0050818 17 16 0,000 0,01846324 0,02805255 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,01960722 0,02976615 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,01960722 0,02974165 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,01960722 0,02971719 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,01960722 0,02969278 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,01960722 0,0296684 ! myelination GO:0042552 17 17 0,000 0,01960722 0,02964406 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,01960722 0,02961976 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,01960722 0,0295955 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,01960722 0,02957128 ! leukocyte adhesion GO:0007159 17 17 0,000 0,01960722 0,0295471 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,01960722 0,02952296 ! sensory perception of smell GO:0007608 17 17 0,000 0,01960722 0,02949886 ! glucose transport GO:0015758 17 17 0,000 0,01960722 0,0294748 ! cell junction assembly GO:0034329 18 17 0,000 0,01960722 0,02945078 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,01960722 0,0294268 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,01960722 0,02940285 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,01960722 0,02937895 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,01960722 0,02935508 ! response to toxin GO:0009636 18 17 0,000 0,01960722 0,02933126 ! negative regulation of cell development GO:0010721 18 17 0,000 0,01960722 0,02930747 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,01960722 0,02928372 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,01960722 0,02926001 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,01960722 0,02923633 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,01960722 0,0292127 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,01960722 0,0291891 ! pigmentation GO:0043473 17 17 0,000 0,01960722 0,02916554 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,01960722 0,02914202 ! adult locomotory behavior GO:0008344 17 17 0,000 0,01960722 0,02911854 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,01960722 0,02909509 ! liver development GO:0001889 17 17 0,000 0,01960722 0,02907169 ! gene silencing GO:0016458 17 17 0,000 0,01960722 0,02904832 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,02075004 0,03071672 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,02075004 0,03069207 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,02075004 0,03066746 ! meiosis I GO:0007127 18 18 0,000 0,02075004 0,03064288 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,02075004 0,03061835 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,02075004 0,03059385 ! membrane docking GO:0022406 18 18 0,000 0,02075004 0,0305694 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,02075004 0,03054498 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,02075004 0,0305206 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,02075004 0,03049627 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,02075004 0,03047197 ! hexose transport GO:0008645 18 18 0,000 0,02075004 0,0304477 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,02075004 0,03042348 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,02075004 0,0303993 ! striated muscle contraction GO:0006941 18 18 0,000 0,02075004 0,03037515 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,02075004 0,03035105 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,02075004 0,03032698 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,02075004 0,03030295 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,02075004 0,03027895 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,02075004 0,030255 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,02075004 0,03023108 ! B cell differentiation GO:0030183 18 18 0,000 0,02075004 0,0302072 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,02075004 0,03018336 ! ensheathment of neurons GO:0007272 18 18 0,000 0,02075004 0,03015956 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,02075004 0,03013579 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,02075004 0,03011206 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,02075004 0,03008837 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,02075004 0,03006471 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,02075004 0,0300411 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,02189169 0,03166906 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,02189169 0,03164422 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,02189169 0,03161942 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,02189169 0,03159466 ! glial cell differentiation GO:0010001 19 19 0,000 0,02189169 0,03156994 ! regulation of pH GO:0006885 19 19 0,000 0,02189169 0,03154525 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,02189169 0,03152061 ! feeding behavior GO:0007631 19 19 0,000 0,02189169 0,031496 ! peroxisome organization GO:0007031 19 19 0,000 0,02189169 0,03147143 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,02189169 0,0314469 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,02189169 0,03142241 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,02189169 0,03139796 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,02189169 0,03137354 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,02189169 0,03134917 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,02189169 0,03132483 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,02189169 0,03130053 ! peripheral nervous system development GO:0007422 19 19 0,000 0,02189169 0,03127626 ! regulation of protein stability GO:0031647 19 19 0,000 0,02189169 0,03125203 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,02189169 0,03122785 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,02189169 0,03120369 ! eye morphogenesis GO:0048592 19 19 0,000 0,02189169 0,03117958 ! regulation of cell shape GO:0008360 21 19 0,000 0,02189169 0,0311555 ! response to heat GO:0009408 19 19 0,000 0,02189169 0,03113146 ! vesicle localization GO:0051648 20 19 0,000 0,02189169 0,03110746 ! regulation of muscle development GO:0048634 21 20 0,000 0,02303217 0,03270284 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,02303217 0,03267767 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,02303217 0,03265253 ! organic ether metabolic process GO:0018904 20 20 0,000 0,02303217 0,03262743 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,02303217 0,03260237 ! neural tube development GO:0021915 21 20 0,000 0,02303217 0,03257735 ! nucleus organization GO:0006997 20 20 0,000 0,02303217 0,03255237 ! phagocytosis GO:0006909 21 20 0,000 0,02303217 0,03252743 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,02303217 0,03250252 ! protein targeting to membrane GO:0006612 22 20 0,000 0,02303217 0,03247765 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,02303217 0,03245282 ! chromatin remodeling GO:0006338 20 20 0,000 0,02303217 0,03242803 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,02303217 0,03240328 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,02303217 0,03237856 ! lipid oxidation GO:0034440 20 20 0,000 0,02303217 0,03235388 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,02303217 0,03232924 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,02303217 0,03230464 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,02303217 0,03228007 ! RNA modification GO:0009451 20 20 0,000 0,02303217 0,03225554 ! single fertilization GO:0007338 21 20 0,000 0,02303217 0,03223105 ! regulation of B cell activation GO:0050864 20 20 0,000 0,02303217 0,03220659 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,02417149 0,03377412 ! mRNA catabolic process GO:0006402 21 21 0,000 0,02417149 0,03374853 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,02417149 0,03372298 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,02417149 0,03369747 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,02417149 0,033672 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,02417149 0,03364657 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,02417149 0,03362118 ! Notch signaling pathway GO:0007219 22 21 0,000 0,02417149 0,03359582 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,02417149 0,0335705 ! organic anion transport GO:0015711 21 21 0,000 0,02417149 0,03354523 ! cholesterol transport GO:0030301 21 21 0,000 0,02417149 0,03351998 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,02417149 0,03349478 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,02417149 0,03346962 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,02417149 0,03344449 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,02417149 0,0334194 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,02417149 0,03339435 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,02417149 0,03336933 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,02417149 0,03334436 ! regulation of proteolysis GO:0030162 21 21 0,000 0,02417149 0,03331942 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,02417149 0,03329451 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,02417149 0,03326965 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,02417149 0,03324482 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,02530965 0,03478425 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,02530965 0,03475833 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,02530965 0,03473245 ! sister chromatid segregation GO:0000819 22 22 0,000 0,02530965 0,03470661 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,02530965 0,03468081 ! regulation of ion transport GO:0043269 22 22 0,000 0,02530965 0,03465504 ! odontogenesis GO:0042476 22 22 0,000 0,02530965 0,03462931 ! cell junction organization GO:0034330 23 22 0,000 0,02530965 0,03460362 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,02530965 0,03457797 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,02530965 0,03455236 ! ovulation cycle process GO:0022602 22 22 0,000 0,02530965 0,03452678 ! spindle organization GO:0007051 22 22 0,000 0,02530965 0,03450125 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,02530965 0,03447575 ! cell chemotaxis GO:0060326 23 22 0,000 0,02530965 0,03445028 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,02530965 0,03442486 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,02530965 0,03439947 ! male sex differentiation GO:0046661 22 22 0,000 0,02530965 0,03437412 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,02530965 0,03434881 ! biopolymer methylation GO:0043414 22 22 0,000 0,02530965 0,03432354 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,02530965 0,0342983 ! detection of external stimulus GO:0009581 23 22 0,000 0,02530965 0,0342731 ! neuron migration GO:0001764 22 22 0,000 0,02530965 0,03424793 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,02530965 0,03422281 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,02530965 0,03419772 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,02530965 0,03417266 ! aerobic respiration GO:0009060 22 22 0,000 0,02530965 0,03414765 ! cytokine production GO:0001816 22 22 0,000 0,02530965 0,03412267 ! cytokinesis GO:0000910 23 22 0,000 0,02530965 0,03409772 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,02530965 0,03407282 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,02644665 0,0355775 ! viral infectious cycle GO:0019058 23 23 0,000 0,02644665 0,03555155 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,02644665 0,03552563 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,02644665 0,03549976 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,02644665 0,03547392 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,02644665 0,03544812 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,02644665 0,03542236 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,02644665 0,03539664 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,02644665 0,03537095 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,02644665 0,0353453 ! positive regulation of growth GO:0045927 23 23 0,000 0,02644665 0,03531969 ! female gonad development GO:0008585 23 23 0,000 0,02644665 0,03529411 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,02644665 0,03526857 ! lipid homeostasis GO:0055088 23 23 0,000 0,02644665 0,03524307 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,02644665 0,03521761 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,02644665 0,03519218 ! cell projection assembly GO:0030031 25 23 0,000 0,02644665 0,03516679 ! mitochondrial transport GO:0006839 24 24 0,000 0,02758248 0,0366507 ! regulation of action potential GO:0001508 24 24 0,000 0,02758248 0,03662429 ! gliogenesis GO:0042063 24 24 0,000 0,02758248 0,03659792 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,02758248 0,03657159 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,02758248 0,0365453 ! T cell differentiation GO:0030217 24 24 0,000 0,02758248 0,03651905 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,02758248 0,03649283 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,02758248 0,03646665 ! ovulation cycle GO:0042698 24 24 0,000 0,02758248 0,03644051 ! fertilization GO:0009566 25 24 0,000 0,02758248 0,03641441 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,02758248 0,03638834 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,02758248 0,03636231 ! glucan metabolic process GO:0044042 25 24 0,000 0,02758248 0,03633632 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,02871716 0,03780409 ! negative regulation of secretion GO:0051048 26 25 0,000 0,02871716 0,0377771 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,02871716 0,03775016 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,02871716 0,03772325 ! cellular component disassembly GO:0022411 26 25 0,000 0,02871716 0,03769638 ! endosome transport GO:0016197 25 25 0,000 0,02871716 0,03766955 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,02871716 0,03764276 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,02871716 0,03761601 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,02871716 0,03758929 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,02871716 0,03756261 ! excretion GO:0007588 25 25 0,000 0,02871716 0,03753597 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,02871716 0,03750937 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,02871716 0,03748281 ! gastrulation GO:0007369 25 25 0,000 0,02871716 0,03745628 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,02871716 0,03742979 ! regulation of endocytosis GO:0030100 25 25 0,000 0,02871716 0,03740334 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,02871716 0,03737692 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,02871716 0,03735055 ! positive regulation of binding GO:0051099 27 26 0,000 0,02985068 0,03879746 ! positive regulation of defense response GO:0031349 26 26 0,000 0,02985068 0,03877012 ! glycolysis GO:0006096 26 26 0,000 0,02985068 0,03874281 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,02985068 0,03871555 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,02985068 0,03868832 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,02985068 0,03866114 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,02985068 0,03863399 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,02985068 0,03860687 ! cellular defense response GO:0006968 26 26 0,000 0,02985068 0,0385798 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,02985068 0,03855277 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,02985068 0,03852577 ! double-strand break repair GO:0006302 27 26 0,000 0,02985068 0,03849881 ! regulation of protein secretion GO:0050708 26 26 0,000 0,02985068 0,03847189 ! germ cell development GO:0007281 27 26 0,000 0,02985068 0,038445 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,02985068 0,03841815 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,02985068 0,03839134 ! response to insulin stimulus GO:0032868 28 26 0,000 0,02985068 0,03836457 ! synapse organization GO:0050808 26 26 0,000 0,02985068 0,03833784 ! chloride transport GO:0006821 27 27 0,000 0,03098304 0,03976444 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,03098304 0,03973677 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,03098304 0,03970913 ! learning or memory GO:0007611 28 27 0,000 0,03098304 0,03968154 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,03098304 0,03965398 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,03098304 0,03962646 ! peptide metabolic process GO:0006518 29 27 0,000 0,03098304 0,03959898 ! activation of caspase activity GO:0006919 27 27 0,000 0,03098304 0,03957154 ! defense response to bacterium GO:0042742 27 27 0,000 0,03098304 0,03954414 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,03098304 0,03951677 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,03098304 0,03948944 ! cell growth GO:0016049 27 27 0,000 0,03098304 0,03946215 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,03211424 0,04087468 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,03211424 0,04084648 ! carbohydrate transport GO:0008643 28 28 0,000 0,03211424 0,04081831 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,03211424 0,04079017 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,03211424 0,04076208 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,03211424 0,04073403 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,03211424 0,04070601 ! histone modification GO:0016570 28 28 0,000 0,03211424 0,04067804 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,03211424 0,0406501 ! developmental growth GO:0048589 28 28 0,000 0,03211424 0,0406222 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,03211424 0,04059434 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,03324429 0,04199398 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,03324429 0,04196522 ! viral reproductive process GO:0022415 29 29 0,000 0,03324429 0,0419365 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,03324429 0,04190781 ! leukocyte migration GO:0050900 30 29 0,000 0,03324429 0,04187917 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,03324429 0,04185056 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,03324429 0,04182199 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,03324429 0,04179347 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,03324429 0,04176498 ! tRNA processing GO:0008033 29 29 0,000 0,03324429 0,04173653 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,03324429 0,04170812 ! covalent chromatin modification GO:0016569 29 29 0,000 0,03324429 0,04167974 ! adult behavior GO:0030534 30 29 0,000 0,03324429 0,04165141 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,03324429 0,04162311 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,03324429 0,04159485 ! response to UV GO:0009411 29 29 0,000 0,03324429 0,04156664 ! transition metal ion transport GO:0000041 31 30 0,000 0,03437318 0,042949 ! RNA catabolic process GO:0006401 30 30 0,000 0,03437318 0,0429199 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,03437318 0,04289084 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,03437318 0,04286182 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,03437318 0,04283284 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,03437318 0,0428039 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,03437318 0,042775 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,03437318 0,04274613 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,03437318 0,04271731 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,03437318 0,04268852 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,03437318 0,04265978 ! response to temperature stimulus GO:0009266 30 30 0,000 0,03437318 0,04263107 ! regulation of ossification GO:0030278 30 30 0,000 0,03437318 0,0426024 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,03437318 0,04257377 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,03437318 0,04254518 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,03437318 0,04251662 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,03437318 0,04248811 ! vesicle organization GO:0016050 30 30 0,000 0,03437318 0,04245963 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,03437318 0,04243119 ! establishment of organelle localization GO:0051656 31 30 0,000 0,03437318 0,04240279 ! regulation of translational initiation GO:0006446 31 31 0,000 0,03550092 0,04376468 ! membrane fusion GO:0006944 31 31 0,000 0,03550092 0,04373542 ! B cell activation GO:0042113 31 31 0,000 0,03550092 0,04370621 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,03550092 0,04367703 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,03550092 0,04364789 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,03550092 0,0436188 ! ion transmembrane transport GO:0034220 31 31 0,000 0,03550092 0,04358974 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,03550092 0,04356072 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,03550092 0,04353173 ! digestion GO:0007586 31 31 0,000 0,03550092 0,04350279 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,03550092 0,04347388 ! regulation of DNA replication GO:0006275 32 31 0,000 0,03550092 0,04344502 ! regulation of heart contraction GO:0008016 31 31 0,000 0,03550092 0,04341619 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,03550092 0,0433874 ! camera-type eye development GO:0043010 31 31 0,000 0,03550092 0,04335864 ! extracellular matrix organization GO:0030198 31 31 0,000 0,03550092 0,04332993 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,03550092 0,04330125 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,03550092 0,04327262 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,03550092 0,04324401 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,03662751 0,04458685 ! cell redox homeostasis GO:0045454 32 32 0,000 0,03662751 0,04455742 ! glucose catabolic process GO:0006007 32 32 0,000 0,03662751 0,04452803 ! lipid modification GO:0030258 32 32 0,000 0,03662751 0,04449868 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,03662751 0,04446936 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,03662751 0,04444009 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,03662751 0,04441085 ! cell maturation GO:0048469 32 32 0,000 0,03662751 0,04438165 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,03662751 0,04435249 ! nuclear export GO:0051168 32 32 0,000 0,03662751 0,04432337 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,03662751 0,04429429 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,03662751 0,04426524 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,03662751 0,04423623 ! negative regulation of cell size GO:0045792 33 33 0,000 0,03775294 0,0455656 ! amino acid transport GO:0006865 33 33 0,000 0,03775294 0,04553578 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,03775294 0,045506 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,03775294 0,04547626 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,03775294 0,04544655 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,03775294 0,04541689 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,03775294 0,04538726 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,03775294 0,04535767 ! regulation of actin filament length GO:0030832 34 34 0,000 0,03887723 0,046678 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,03887723 0,04664761 ! response to metal ion GO:0010038 34 34 0,000 0,03887723 0,04661726 ! muscle cell differentiation GO:0042692 35 34 0,000 0,03887723 0,04658695 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,03887723 0,04655668 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,03887723 0,04652645 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,03887723 0,04649625 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,03887723 0,0464661 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,03887723 0,04643599 ! secondary metabolic process GO:0019748 34 34 0,000 0,03887723 0,04640591 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,03887723 0,04637588 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,03887723 0,04634588 ! viral reproduction GO:0016032 34 34 0,000 0,03887723 0,04631592 ! detection of stimulus GO:0051606 36 34 0,000 0,03887723 0,046286 ! acute inflammatory response GO:0002526 35 35 0,000 0,04000036 0,04759242 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,04000036 0,04756172 ! regulation of cellular component size GO:0032535 35 35 0,000 0,04000036 0,04753105 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,04000036 0,04750043 ! mesoderm development GO:0007498 35 35 0,000 0,04000036 0,04746984 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,04000036 0,0474393 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,04000036 0,04740879 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,04000036 0,04737832 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,04000036 0,04734789 ! inorganic anion transport GO:0015698 35 35 0,000 0,04000036 0,0473175 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,04000036 0,04728715 ! regulation of immune effector process GO:0002697 35 35 0,000 0,04000036 0,04725684 ! hydrogen transport GO:0006818 36 36 0,000 0,04112235 0,04855124 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,04112235 0,04852016 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,04112235 0,04848911 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,04112235 0,04845811 ! regulation of mitosis GO:0007088 37 36 0,000 0,04112235 0,04842715 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,04112235 0,04839622 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,04112235 0,04836534 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,04112235 0,04833449 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,04112235 0,04830369 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,04112235 0,04827292 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,04112235 0,04824219 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,04112235 0,04821151 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,04112235 0,04818086 ! gonad development GO:0008406 36 36 0,000 0,04112235 0,04815025 ! regulation of lipase activity GO:0060191 36 36 0,000 0,04112235 0,04811967 ! activation of immune response GO:0002253 36 36 0,000 0,04112235 0,04808914 ! coagulation GO:0050817 39 36 0,000 0,04112235 0,04805865 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,04224319 0,04933726 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,04224319 0,04930601 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,04224319 0,04927481 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,04224319 0,04924364 ! response to drug GO:0042493 37 37 0,000 0,04224319 0,04921251 ! lung development GO:0030324 38 37 0,000 0,04224319 0,04918142 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,04224319 0,04915037 ! eye development GO:0001654 37 37 0,000 0,04224319 0,04911936 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,04224319 0,04908839 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,04224319 0,04905746 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,04224319 0,04902657 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,04224319 0,04899572 ! adaptive immune response GO:0002250 37 37 0,000 0,04224319 0,0489649 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,04336288 0,05023117 ! neurotransmitter transport GO:0006836 40 38 0,000 0,04336288 0,05019961 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,04336288 0,0501681 ! exocytosis GO:0006887 40 38 0,000 0,04336288 0,05013663 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,04336288 0,05010519 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,04336288 0,0500738 ! chromosome segregation GO:0007059 38 38 0,000 0,04336288 0,05004245 ! hexose catabolic process GO:0019320 38 38 0,000 0,04336288 0,05001113 ! RNA elongation GO:0006354 38 38 0,000 0,04336288 0,04997985 ! meiotic cell cycle GO:0051321 38 38 0,000 0,04336288 0,04994862 ! axon guidance GO:0007411 39 38 0,000 0,04336288 0,04991742 ! regulation of neurological system process GO:0031644 38 38 0,000 0,04336288 0,04988626 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,04336288 0,04985514 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,04448143 0,05110927 ! hemostasis GO:0007599 42 39 0,000 0,04448143 0,05107742 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,04448143 0,05104562 ! respiratory tube development GO:0030323 40 39 0,000 0,04448143 0,05101386 ! response to unfolded protein GO:0006986 39 39 0,000 0,04448143 0,05098213 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,04448143 0,05095045 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,04448143 0,0509188 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,04448143 0,05088719 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,04448143 0,05085562 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,04448143 0,0508241 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,04448143 0,05079261 ! respiratory system development GO:0060541 40 39 0,000 0,04448143 0,05076116 ! developmental maturation GO:0021700 39 39 0,000 0,04448143 0,05072974 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,04448143 0,05069837 ! limb development GO:0060173 39 39 0,000 0,04448143 0,05066704 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,04448143 0,05063574 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,04559883 0,0518757 ! DNA catabolic process GO:0006308 41 40 0,000 0,04559883 0,0518437 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,04559883 0,05181174 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,04559883 0,05177981 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,04559883 0,05174793 ! organelle localization GO:0051640 41 40 0,000 0,04559883 0,05171609 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,04671509 0,05294951 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,04671509 0,05291697 ! amine catabolic process GO:0009310 42 41 0,000 0,04671509 0,05288446 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,04671509 0,052852 ! regulation of caspase activity GO:0043281 41 41 0,000 0,04671509 0,05281957 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,04671509 0,05278719 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,04671509 0,05275484 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,04671509 0,05272254 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,04671509 0,05269027 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,0478302 0,05391502 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,0478302 0,05388207 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,0478302 0,05384915 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,0478302 0,05381628 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,0478302 0,05378344 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,0478302 0,05375065 ! protein ubiquitination GO:0016567 43 42 0,000 0,0478302 0,05371789 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,0478302 0,05368518 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,0478302 0,0536525 ! forebrain development GO:0030900 43 42 0,000 0,0478302 0,05361987 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,0478302 0,05358727 ! reproductive structure development GO:0048608 43 43 0,000 0,04894418 0,05480202 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,04894418 0,05476874 ! mitochondrion organization GO:0007005 44 43 0,000 0,04894418 0,05473551 ! alcohol catabolic process GO:0046164 43 43 0,000 0,04894418 0,05470232 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,04894418 0,05466916 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,04894418 0,05463605 ! humoral immune response GO:0006959 44 44 0,000 0,05005701 0,05584447 ! mRNA transport GO:0051028 44 44 0,000 0,05005701 0,05581069 ! protein import into nucleus GO:0006606 44 44 0,000 0,05005701 0,05577695 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,05005701 0,05574325 ! vitamin metabolic process GO:0006766 44 44 0,000 0,05005701 0,05570958 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,05005701 0,05567596 ! amine biosynthetic process GO:0009309 46 45 0,000 0,05116871 0,05687812 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,05116871 0,05684384 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,05116871 0,05680959 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,05116871 0,05677539 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,05116871 0,05674123 ! nuclear import GO:0051170 45 45 0,000 0,05116871 0,05670711 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,05116871 0,05667303 ! protein processing GO:0016485 45 45 0,000 0,05116871 0,05663899 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,05227926 0,05783354 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,05227926 0,05779885 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,05227926 0,0577642 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,05227926 0,05772959 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,05227926 0,05769502 ! regulation of membrane potential GO:0042391 46 46 0,000 0,05227926 0,05766049 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,05338868 0,05884889 ! regulation of blood pressure GO:0008217 48 47 0,000 0,05338868 0,05881371 ! sex differentiation GO:0007548 47 47 0,000 0,05338868 0,05877858 ! amine transport GO:0015837 47 47 0,000 0,05338868 0,05874348 ! rhythmic process GO:0048511 47 47 0,000 0,05338868 0,05870844 ! calcium ion transport GO:0006816 48 48 0,000 0,05449696 0,05989141 ! actin filament organization GO:0007015 50 48 0,000 0,05449696 0,05985572 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,05449696 0,05982007 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,05449696 0,05978446 ! protein localization in nucleus GO:0034504 48 48 0,000 0,05449696 0,0597489 ! DNA recombination GO:0006310 48 48 0,000 0,05449696 0,05971338 ! leukocyte differentiation GO:0002521 50 49 0,000 0,05560411 0,0608903 ! ossification GO:0001503 50 49 0,000 0,05560411 0,06085414 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 0,000 0,05560411 0,06081802 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,05560411 0,06078195 ! divalent metal ion transport GO:0070838 49 49 0,000 0,05560411 0,06074592 ! response to nutrient GO:0007584 49 49 0,000 0,05560411 0,06070994 ! response to bacterium GO:0009617 50 49 0,000 0,05560411 0,06067399 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,05560411 0,06063809 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,05560411 0,06060223 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,05671012 0,06177113 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,05671012 0,06173464 ! chromatin assembly GO:0031497 50 50 0,000 0,05671012 0,0616982 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,05671012 0,0616618 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,05671012 0,06162544 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,05671012 0,06158913 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,05671012 0,06155286 ! transcription initiation GO:0006352 50 50 0,000 0,05671012 0,06151663 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,05671012 0,06148044 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,057815 0,06264141 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,057815 0,06260461 ! positive regulation of immune response GO:0050778 51 51 0,000 0,057815 0,06256785 ! rRNA metabolic process GO:0016072 51 51 0,000 0,057815 0,06253113 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,057815 0,06249445 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,057815 0,06245782 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,057815 0,06242123 ! protein maturation GO:0051604 51 51 0,000 0,057815 0,06238469 ! RNA localization GO:0006403 52 52 0,000 0,05891874 0,06353847 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,05891874 0,06350131 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,05891874 0,0634642 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,05891874 0,06342713 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,05891874 0,0633901 ! response to light stimulus GO:0009416 53 52 0,000 0,05891874 0,06335312 ! sodium ion transport GO:0006814 53 53 0,000 0,06002136 0,06450109 ! tRNA metabolic process GO:0006399 53 53 0,000 0,06002136 0,0644635 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,06002136 0,06442595 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,06002136 0,06438845 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,06002136 0,064351 ! regulation of T cell activation GO:0050863 53 53 0,000 0,06002136 0,06431358 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,06112284 0,06545578 ! response to virus GO:0009615 54 54 0,000 0,06112284 0,06541777 ! hormone metabolic process GO:0042445 55 54 0,000 0,06112284 0,0653798 ! sulfur metabolic process GO:0006790 55 54 0,000 0,06112284 0,06534188 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,06112284 0,065304 ! nucleosome organization GO:0034728 55 55 0,000 0,0622232 0,06644111 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,0622232 0,06640264 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,0622232 0,06636421 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,0622232 0,06632582 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,0622232 0,06628749 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,06332242 0,06741954 ! reproductive developmental process GO:0003006 56 56 0,000 0,06332242 0,06738061 ! extracellular structure organization GO:0043062 56 56 0,000 0,06332242 0,06734173 ! ATP metabolic process GO:0046034 57 57 0,000 0,06442052 0,06847002 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,06442052 0,06843056 ! innate immune response GO:0045087 58 58 0,000 0,06551749 0,06955572 ! dephosphorylation GO:0016311 60 59 0,000 0,06661334 0,0706784 ! carboxylic acid transport GO:0046942 59 59 0,000 0,06661334 0,07063773 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,06661334 0,07059711 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,06661334 0,07055654 ! protein localization in organelle GO:0033365 59 59 0,000 0,06661334 0,07051601 ! immune effector process GO:0002252 59 59 0,000 0,06661334 0,07047553 ! potassium ion transport GO:0006813 60 60 0,000 0,06770806 0,07159263 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,06770806 0,07155158 ! protein polymerization GO:0051258 65 60 0,000 0,06770806 0,07151057 ! cellular respiration GO:0045333 62 61 0,000 0,06880166 0,07262397 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,06880166 0,0725824 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,06880166 0,07254088 ! lipid transport GO:0006869 62 62 0,000 0,06989413 0,07365059 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,06989413 0,0736085 ! axonogenesis GO:0007409 66 62 0,000 0,06989413 0,07356647 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,06989413 0,07352448 ! protein import GO:0017038 62 62 0,000 0,06989413 0,07348253 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,06989413 0,07344064 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,06989413 0,07339879 ! regulation of secretion GO:0051046 65 63 0,000 0,07098548 0,07450242 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,07098548 0,07446002 ! glucose metabolic process GO:0006006 63 63 0,000 0,07098548 0,07441766 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,07098548 0,07437535 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,07098548 0,0743331 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,07207572 0,07543188 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,07207572 0,07538907 ! angiogenesis GO:0001525 65 64 0,000 0,07207572 0,07534631 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,07207572 0,0753036 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,07207572 0,07526093 ! anion transport GO:0006820 65 65 0,000 0,07316483 0,07635492 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,07316483 0,0763117 ! regulation of hormone levels GO:0010817 66 65 0,000 0,07316483 0,07626854 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,07425282 0,07735893 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,07425282 0,07731523 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,07425282 0,07727157 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,07425282 0,07722797 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,0753397 0,0783142 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,0753397 0,07827005 ! muscle contraction GO:0006936 67 67 0,000 0,0753397 0,07822595 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,0753397 0,07818191 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,0753397 0,07813791 ! response to radiation GO:0009314 70 68 0,000 0,07642546 0,07921942 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,07642546 0,07917489 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,07642546 0,07913041 ! regulation of cell size GO:0008361 68 68 0,000 0,07642546 0,07908598 ! regulation of translation GO:0006417 69 69 0,000 0,07751011 0,08016337 ! response to nutrient levels GO:0031667 69 69 0,000 0,07751011 0,08011841 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,07751011 0,0800735 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,07751011 0,08002864 ! positive regulation of transport GO:0051050 71 70 0,000 0,07859363 0,08110194 ! cell part morphogenesis GO:0032990 75 70 0,000 0,07859363 0,08105656 ! growth GO:0040007 70 70 0,000 0,07859363 0,08101122 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,07859363 0,08096594 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,07967605 0,08203517 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,07967605 0,08198937 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,07967605 0,08194362 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,07967605 0,08189791 ! regulation of cell activation GO:0050865 71 71 0,000 0,07967605 0,08185226 ! secretion by cell GO:0032940 75 72 0,000 0,08075735 0,08291688 ! muscle system process GO:0003012 72 72 0,000 0,08075735 0,08287071 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,08075735 0,0828246 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,08075735 0,08277853 ! electron transport chain GO:0022900 75 74 0,000 0,08291662 0,0849446 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,08291662 0,08489741 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,0839946 0,08595338 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,0839946 0,08590568 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,08614721 0,08805841 ! microtubule-based movement GO:0007018 82 78 0,000 0,08722186 0,08910747 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,08722186 0,08905811 ! metal ion homeostasis GO:0055065 78 78 0,000 0,08722186 0,08900879 ! regulation of immune response GO:0050776 78 78 0,000 0,08722186 0,08895954 ! nuclear transport GO:0051169 79 79 0,000 0,0882954 0,09000466 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,08936783 0,09104749 ! neuron projection development GO:0031175 85 80 0,000 0,08936783 0,09099719 ! lymphocyte activation GO:0046649 82 81 0,000 0,09043917 0,09203721 ! lipid catabolic process GO:0016042 82 81 0,000 0,09043917 0,09198641 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,09257852 0,09411043 ! ncRNA processing GO:0034470 83 83 0,000 0,09257852 0,09405855 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,09257852 0,09400673 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,09364655 0,09503887 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,09471347 0,09606876 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,09471347 0,09601591 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,0957793 0,09704302 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,0957793 0,0969897 ! male gamete generation GO:0048232 90 88 0,000 0,09790766 0,09909051 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,09790766 0,09903612 ! chemotaxis GO:0006935 90 89 0,000 0,0989702 0,10005599 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,10003164 0,10107363 ! brain development GO:0007420 91 90 0,000 0,10003164 0,10101825 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,10109198 0,10203314 ! DNA replication GO:0006260 91 91 0,000 0,10109198 0,1019773 ! visual perception GO:0007601 93 92 0,000 0,10215123 0,10298945 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,10215123 0,10293315 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,10215123 0,1028769 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,10215123 0,10282071 ! blood vessel development GO:0001568 95 94 0,000 0,10426646 0,10489252 ! epidermis development GO:0008544 94 94 0,000 0,10426646 0,10483529 ! cofactor metabolic process GO:0051186 95 94 0,000 0,10426646 0,10477813 ! regulation of cell growth GO:0001558 97 96 0,000 0,10637733 0,1068411 ! vasculature development GO:0001944 97 96 0,000 0,10637733 0,10678291 ! endocytosis GO:0006897 99 98 0,000 0,10848384 0,10883817 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,10848384 0,10877896 ! blood circulation GO:0008015 99 98 0,000 0,10848384 0,1087198 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,10848384 0,10866072 ! ectoderm development GO:0007398 99 99 0,000 0,10953547 0,10965446 ! response to hormone stimulus GO:0009725 102 100 0,000 0,11058601 0,11064604 ! response to other organism GO:0051707 101 100 0,000 0,11058601 0,11058601