pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/7534-9-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 9 5 2,000 9,528E-09 2,328E-05 GO:0019405|alditol catabolic process, ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 2,71E-07 3,31E-04 ! fructose metabolic process GO:0006000 25 16 2,000 5,295E-07 4,312E-04 ! protein localization in mitochondrion GO:0070585 39 20 2,000 1,075E-06 6,565E-04 GO:0006626|protein targeting to mitochondrion, ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 2,000 1,253E-06 6,123E-04 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 2,161E-06 8,799E-04 ! osteoblast differentiation GO:0001649 63 26 2,000 2,441E-06 8,52E-04 ! alditol metabolic process GO:0019400 44 26 2,000 2,441E-06 7,455E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 2,991E-06 8,118E-04 ! sperm motility GO:0030317 37 28 2,000 3,072E-06 7,504E-04 ! hexose biosynthetic process GO:0019319 53 32 2,000 4,638E-06 1,03E-03 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 6,657E-06 1,355E-03 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 2,000 7,24E-06 1,361E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of viral genome replication GO:0045070 9 5 1,000 9,954E-06 1,737E-03 ! alcohol biosynthetic process GO:0046165 65 42 2,000 1,066E-05 1,736E-03 ! polyol metabolic process GO:0019751 77 45 2,000 1,315E-05 2,008E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,406E-05 2,02E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 1,492E-05 2,025E-03 GO:0046530|photoreceptor cell differentiation, ! regulation of retroviral genome replication GO:0045091 8 6 1,000 1,492E-05 1,919E-03 ! mitochondrial transport GO:0006839 94 48 2,000 1,599E-05 1,954E-03 ! response to UV GO:0009411 120 55 2,000 2,414E-05 2,808E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 2,689E-05 2,986E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,782E-05 2,955E-03 ! DNA topological change GO:0006265 12 8 1,000 2,782E-05 2,832E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 1,000 2,782E-05 2,719E-03 ! regulation of Rac protein signal transduction GO:0035020 18 8 1,000 2,782E-05 2,614E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 1,000 2,782E-05 2,517E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 4,465E-05 3,896E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 4,465E-05 3,762E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 4,465E-05 3,636E-03 ! DNA ligation GO:0006266 18 10 1,000 4,465E-05 3,519E-03 ! positive regulation of viral reproduction GO:0048524 19 10 1,000 4,465E-05 3,409E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 4,57E-05 3,383E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 4,774E-05 3,431E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 5,423E-05 3,785E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 5,423E-05 3,68E-03 ! Golgi vesicle budding GO:0048194 26 11 1,000 5,454E-05 3,601E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 5,454E-05 3,506E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 6,541E-05 4,097E-03 ! establishment of cell polarity GO:0030010 21 12 1,000 6,541E-05 3,995E-03 ! positive regulation of ligase activity GO:0051351 130 77 2,000 6,629E-05 3,95E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 7,156E-05 4,162E-03 ! regulation of adenylate cyclase activity GO:0045761 165 83 2,000 8,291E-05 4,711E-03 ! intracellular protein transmembrane transport GO:0065002 165 83 2,000 8,291E-05 4,604E-03 ! regulation of ligase activity GO:0051340 147 84 2,000 8,593E-05 4,665E-03 ! regulation of cyclase activity GO:0031279 168 85 2,000 8,901E-05 4,727E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 1,000 9,007E-05 4,682E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of cAMP biosynthetic process GO:0030817 173 86 2,000 9,216E-05 4,691E-03 ! regulation of lyase activity GO:0051339 169 86 2,000 9,216E-05 4,595E-03 ! mitochondrion organization GO:0007005 159 87 2,000 9,539E-05 4,661E-03 ! alcohol catabolic process GO:0046164 142 87 2,000 9,539E-05 4,569E-03 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 1,021E-04 4,795E-03 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 2,000 1,09E-04 5,025E-03 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 2,000 1,09E-04 4,932E-03 ! bone development GO:0060348 206 92 2,000 1,126E-04 5,002E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 1,163E-04 5,073E-03 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 1,2E-04 5,145E-03 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 1,239E-04 5,218E-03 ! membrane budding GO:0006900 42 17 1,000 1,343E-04 5,563E-03 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 1,358E-04 5,531E-03 ! regulation of viral genome replication GO:0045069 30 18 1,000 1,51E-04 6,049E-03 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 1,687E-04 6,648E-03 ! visual learning GO:0008542 38 19 1,000 1,687E-04 6,542E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 1,873E-04 7,151E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! cell-cell junction organization GO:0045216 43 20 1,000 1,873E-04 7,041E-03 ! apoptotic nuclear changes GO:0030262 34 22 1,000 2,275E-04 8,42E-03 ! cell aging GO:0007569 48 22 1,000 2,275E-04 8,294E-03 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 2,275E-04 8,172E-03 ! positive regulation of B cell activation GO:0050871 42 22 1,000 2,275E-04 8,054E-03 ! visual behavior GO:0007632 46 23 1,000 2,49E-04 8,689E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 2,49E-04 8,567E-03 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 2,714E-04 9,21E-03 ! regulation of viral reproduction GO:0050792 41 24 1,000 2,714E-04 9,084E-03 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 2,714E-04 8,961E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 2,949E-04 9,604E-03 ! chromosome condensation GO:0030261 48 25 1,000 2,949E-04 9,478E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 3,192E-04 0,01012795 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 3,192E-04 9,998E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 3,708E-04 0,01146675 ! fat cell differentiation GO:0045444 57 28 1,000 3,708E-04 0,01132341 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 3,98E-04 0,01200438 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 3,98E-04 0,01185799 ! regulation of B cell activation GO:0050864 55 30 1,000 4,262E-04 0,01254392 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 4,553E-04 0,01324095 ! eye morphogenesis GO:0048592 65 31 1,000 4,553E-04 0,01308518 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 5,811E-04 0,01650661 ! protein targeting to membrane GO:0006612 75 36 1,000 6,149E-04 0,0172657 ! cell junction organization GO:0034330 96 37 1,000 6,496E-04 0,01803341 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 6,852E-04 0,01880941 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 7,218E-04 0,01959337 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 82 40 1,000 7,593E-04 0,02038497 ! nucleus organization GO:0006997 73 40 1,000 7,593E-04 0,0201634 ! establishment or maintenance of cell polarity GO:0007163 96 41 1,000 7,978E-04 0,02095615 ! striated muscle cell differentiation GO:0051146 91 43 1,000 8,774E-04 0,02280277 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 9,607E-04 0,02470509 ! keratinocyte differentiation GO:0030216 81 45 1,000 9,607E-04 0,02444775 ! positive regulation of cell cycle GO:0045787 96 48 1,000 1,093E-03 0,02751587 ! response to calcium ion GO:0051592 94 49 1,000 1,138E-03 0,02837598 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 1,138E-03 0,02808935 ! epidermal cell differentiation GO:0009913 87 50 1,000 1,185E-03 0,02894872 ! vesicle organization GO:0016050 127 53 1,000 1,33E-03 0,03218047 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 1,33E-03 0,03186498 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 1,000 1,33E-03 0,03155561 ! aging GO:0007568 112 58 1,000 1,591E-03 0,03737 ! negative regulation of cell growth GO:0030308 142 67 1,000 2,116E-03 0,04922644 ! chromosome segregation GO:0007059 127 67 1,000 2,116E-03 0,04876204 ! negative regulation of cell size GO:0045792 144 69 1,000 2,242E-03 0,05119072 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 2,242E-03 0,05071673 ! negative regulation of kinase activity GO:0033673 145 70 1,000 2,307E-03 0,05169657 ! actin filament organization GO:0007015 167 72 1,000 2,438E-03 0,05414862 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 2,573E-03 0,05663293 ! negative regulation of transferase activity GO:0051348 155 74 1,000 2,573E-03 0,05612728 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 2,642E-03 0,0571184 ! eye development GO:0001654 155 75 1,000 2,642E-03 0,05661737 ! learning or memory GO:0007611 161 76 1,000 2,712E-03 0,05760533 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 2,854E-03 0,06009818 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 2,926E-03 0,06109336 ! regulation of synaptic transmission GO:0050804 159 79 1,000 2,926E-03 0,06057562 ! muscle cell differentiation GO:0042692 178 81 1,000 3,073E-03 0,06308625 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 3,073E-03 0,06256053 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 3,223E-03 0,06508212 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 3,3E-03 0,06608105 ! negative regulation of growth GO:0045926 168 85 1,000 3,377E-03 0,06708058 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 3,377E-03 0,06653961 ! positive regulation of cell activation GO:0050867 161 86 1,000 3,456E-03 0,06753601 GO:0002696|positive regulation of leukocyte activation, ! regulation of neurological system process GO:0031644 175 89 1,000 3,695E-03 0,07164785 ! response to inorganic substance GO:0010035 173 90 1,000 3,777E-03 0,07265311 ! positive regulation of protein modification process GO:0031401 156 90 1,000 3,777E-03 0,07208551 ! response to unfolded protein GO:0006986 139 90 1,000 3,777E-03 0,07152671 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 4,027E-03 0,07567041 ! response to protein stimulus GO:0051789 158 96 1,000 4,284E-03 0,07989058 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 5,054E-03 0,09354065 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 5,054E-03 0,09283734 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 5,054E-03 0,09214452 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 5,054E-03 0,09146197 ! positive regulation of helicase activity GO:0051096 12 5 0,000 5,054E-03 0,09078946 ! neuron fate determination GO:0048664 7 5 0,000 5,054E-03 0,09012676 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,054E-03 0,08947367 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 5,054E-03 0,08882997 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 5,054E-03 0,08819547 ! polyol transport GO:0015791 12 5 0,000 5,054E-03 0,08756997 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 5,054E-03 0,08695328 ! response to superoxide GO:0000303 10 5 0,000 5,054E-03 0,08634522 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,054E-03 0,0857456 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 5,054E-03 0,08515425 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 5,054E-03 0,084571 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 5,054E-03 0,08399569 ! female meiosis GO:0007143 10 5 0,000 5,054E-03 0,08342815 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 5,054E-03 0,08286823 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 5,054E-03 0,08231577 ! hypothalamus development GO:0021854 9 5 0,000 5,054E-03 0,08177064 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 5,054E-03 0,08123267 ! cobalt ion transport GO:0006824 11 5 0,000 5,054E-03 0,08070174 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 5,054E-03 0,0801777 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 5,054E-03 0,07966043 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 5,054E-03 0,07914978 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 5,054E-03 0,07864564 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 5,054E-03 0,07814789 ! embryonic camera-type eye development GO:0031076 12 5 0,000 5,054E-03 0,07765639 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 5,054E-03 0,07717104 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,054E-03 0,07669172 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 5,054E-03 0,07621831 ! transposition GO:0032196 9 5 0,000 5,054E-03 0,07575071 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 5,054E-03 0,07528882 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 5,054E-03 0,07483252 ! negative chemotaxis GO:0050919 16 5 0,000 5,054E-03 0,07438172 ! positive regulation of histone modification GO:0031058 6 5 0,000 5,054E-03 0,07393632 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,054E-03 0,07349623 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 5,054E-03 0,07306134 ! behavioral response to pain GO:0048266 10 5 0,000 5,054E-03 0,07263157 ! clathrin coat assembly GO:0048268 15 5 0,000 5,054E-03 0,07220682 ! Notch receptor processing GO:0007220 11 5 0,000 5,054E-03 0,07178701 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,054E-03 0,07137206 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 5,054E-03 0,07096187 ! micturition GO:0060073 9 5 0,000 5,054E-03 0,07055638 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 5,054E-03 0,07015549 ! copulation GO:0007620 9 5 0,000 5,054E-03 0,06975913 ! glial cell fate commitment GO:0021781 14 5 0,000 5,054E-03 0,06936723 ! protein maturation by protein folding GO:0022417 14 5 0,000 5,054E-03 0,0689797 ! bioluminescence GO:0008218 9 5 0,000 5,054E-03 0,06859648 ! spermidine metabolic process GO:0008216 7 5 0,000 5,054E-03 0,06821749 ! regulation of potassium ion transport GO:0043266 10 5 0,000 5,054E-03 0,06784267 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 5,054E-03 0,06747195 ! apoptotic cell clearance GO:0043277 23 5 0,000 5,054E-03 0,06710525 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 5,054E-03 0,06674252 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 5,054E-03 0,06638369 ! lipoprotein particle clearance GO:0034381 10 5 0,000 5,054E-03 0,0660287 ! grooming behavior GO:0007625 6 5 0,000 5,054E-03 0,06567748 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 5,054E-03 0,06532998 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 5,054E-03 0,06498614 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 5,054E-03 0,0646459 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,054E-03 0,0643092 ! response to protozoan GO:0001562 13 5 0,000 5,054E-03 0,06397599 ! positive regulation of glycolysis GO:0045821 13 5 0,000 5,054E-03 0,06364622 ! lymph vessel development GO:0001945 10 5 0,000 5,054E-03 0,06331983 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 5,054E-03 0,06299677 ! endochondral ossification GO:0001958 17 5 0,000 5,054E-03 0,06267699 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 5,054E-03 0,06236044 ! single strand break repair GO:0000012 8 5 0,000 5,054E-03 0,06204707 ! parathyroid gland development GO:0060017 14 5 0,000 5,054E-03 0,06173683 ! anagen GO:0042640 7 5 0,000 5,054E-03 0,06142968 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 5,054E-03 0,06112558 ! cytokine secretion GO:0050663 15 5 0,000 5,054E-03 0,06082446 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 5,054E-03 0,0605263 ! ceramide catabolic process GO:0046514 7 5 0,000 5,054E-03 0,06023105 ! skeletal myofibril assembly GO:0014866 12 5 0,000 5,054E-03 0,05993867 ! smooth muscle tissue development GO:0048745 32 5 0,000 5,054E-03 0,05964911 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,054E-03 0,05936234 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 5,054E-03 0,05907831 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 5,054E-03 0,05879698 ! cardiac muscle fiber development GO:0048739 12 5 0,000 5,054E-03 0,05851832 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,054E-03 0,05824229 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 5,054E-03 0,05796886 ! neutrophil mediated immunity GO:0002446 7 5 0,000 5,054E-03 0,05769797 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 5,054E-03 0,05742961 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 5,054E-03 0,05716373 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 5,054E-03 0,05690031 ! glycine biosynthetic process GO:0006545 7 5 0,000 5,054E-03 0,05663929 ! microvillus organization GO:0032528 8 5 0,000 5,054E-03 0,05638067 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 5,054E-03 0,05612439 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 5,054E-03 0,05587044 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 5,054E-03 0,05561877 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 5,054E-03 0,05536936 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 5,054E-03 0,05512217 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 5,054E-03 0,05487718 ! polyol biosynthetic process GO:0046173 6 5 0,000 5,054E-03 0,05463436 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 5,054E-03 0,05439368 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,054E-03 0,05415511 ! muscle cell migration GO:0014812 8 5 0,000 5,054E-03 0,05391863 ! mitochondrial fission GO:0000266 8 5 0,000 5,054E-03 0,0536842 ! sister chromatid cohesion GO:0007062 15 5 0,000 5,054E-03 0,0534518 ! response to tumor necrosis factor GO:0034612 10 5 0,000 5,054E-03 0,05322141 ! mRNA transcription GO:0009299 10 5 0,000 5,054E-03 0,05299299 ! nerve growth factor processing GO:0032455 9 5 0,000 5,054E-03 0,05276652 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 5,054E-03 0,05254198 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 5,054E-03 0,05231935 ! anaerobic glycolysis GO:0019642 6 5 0,000 5,054E-03 0,05209859 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 5,054E-03 0,05187969 ! monocyte activation GO:0042117 10 5 0,000 5,054E-03 0,05166262 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 5,054E-03 0,05144736 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 5,054E-03 0,05123388 ! response to food GO:0032094 6 5 0,000 5,054E-03 0,05102217 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 5,054E-03 0,05081221 ! positive regulation of transporter activity GO:0032411 8 5 0,000 5,054E-03 0,05060396 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 5,054E-03 0,05039741 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,054E-03 0,05019255 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 5,054E-03 0,04998934 ! forebrain neuron development GO:0021884 13 5 0,000 5,054E-03 0,04978777 ! lipoprotein catabolic process GO:0042159 11 5 0,000 5,054E-03 0,04958782 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 5,054E-03 0,04938946 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 5,054E-03 0,04919269 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 5,054E-03 0,04899748 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,054E-03 0,04880382 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 5,054E-03 0,04861168 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 5,054E-03 0,04842104 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 5,054E-03 0,0482319 ! lipid glycosylation GO:0030259 7 5 0,000 5,054E-03 0,04804423 ! nucleobase transport GO:0015851 6 5 0,000 5,054E-03 0,04785801 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,054E-03 0,04767323 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 5,054E-03 0,04748987 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 5,054E-03 0,04730792 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 5,054E-03 0,04712735 ! basic amino acid transport GO:0015802 12 5 0,000 5,054E-03 0,04694816 ! cellular glucose homeostasis GO:0001678 6 5 0,000 5,054E-03 0,04677033 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 5,054E-03 0,04659383 ! actin nucleation GO:0045010 11 5 0,000 5,054E-03 0,04641867 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,054E-03 0,04624482 ! depurination GO:0045007 5 5 0,000 5,054E-03 0,04607226 ! depyrimidination GO:0045008 10 5 0,000 5,054E-03 0,04590099 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,054E-03 0,04573099 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,054E-03 0,04556224 ! G2/M transition checkpoint GO:0031576 8 5 0,000 5,054E-03 0,04539473 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 5,054E-03 0,04522845 ! zinc ion homeostasis GO:0055069 9 5 0,000 5,054E-03 0,04506338 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 5,054E-03 0,04489951 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 5,054E-03 0,04473683 ! forebrain morphogenesis GO:0048853 13 5 0,000 5,054E-03 0,04457533 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 5,054E-03 0,04441499 ! activated T cell proliferation GO:0050798 16 5 0,000 5,054E-03 0,04425579 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 5,054E-03 0,04409774 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 5,054E-03 0,0439408 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,054E-03 0,04378499 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,054E-03 0,04363027 ! gamma-delta T cell activation GO:0046629 6 5 0,000 5,054E-03 0,04347664 ! response to arsenic GO:0046685 11 5 0,000 5,054E-03 0,04332409 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 5,054E-03 0,04317261 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 5,054E-03 0,04302218 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 5,054E-03 0,0428728 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 5,054E-03 0,04272445 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 5,054E-03 0,04257712 ! response to mercury ion GO:0046689 8 5 0,000 5,054E-03 0,04243081 ! response to cadmium ion GO:0046686 7 5 0,000 5,054E-03 0,0422855 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 5,054E-03 0,04214118 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 5,054E-03 0,04199784 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 5,054E-03 0,04185548 ! bile acid biosynthetic process GO:0006699 7 5 0,000 5,054E-03 0,04171407 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,054E-03 0,04157362 ! ganglioside catabolic process GO:0006689 12 5 0,000 5,054E-03 0,04143411 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 5,054E-03 0,04129554 ! decidualization GO:0046697 11 5 0,000 5,054E-03 0,04115789 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 5,054E-03 0,04102115 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 5,054E-03 0,04088532 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 5,054E-03 0,04075038 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 5,054E-03 0,04061634 ! embryonic cleavage GO:0040016 6 5 0,000 5,054E-03 0,04048317 ! peroxisome fission GO:0016559 5 5 0,000 5,054E-03 0,04035087 ! histone demethylation GO:0016577 13 5 0,000 5,054E-03 0,04021943 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 5,054E-03 0,04008885 ! mitotic recombination GO:0006312 9 5 0,000 5,054E-03 0,03995911 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 5,054E-03 0,03983021 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,054E-03 0,03970214 ! metaphase plate congression GO:0051310 7 5 0,000 5,054E-03 0,03957489 ! regulation of sterol transport GO:0032371 7 5 0,000 5,054E-03 0,03944845 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 5,054E-03 0,03932282 ! enteric nervous system development GO:0048484 8 5 0,000 5,054E-03 0,03919799 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 5,054E-03 0,03907394 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 5,054E-03 0,03895068 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 5,054E-03 0,0388282 ! muscle cell proliferation GO:0033002 12 5 0,000 5,054E-03 0,03870648 ! skeletal muscle regeneration GO:0043403 8 5 0,000 5,054E-03 0,03858552 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 5,054E-03 0,03846532 ! B cell homeostasis GO:0001782 13 5 0,000 5,054E-03 0,03834586 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 5,054E-03 0,03822714 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 5,054E-03 0,03810915 ! metaphase GO:0051323 11 5 0,000 5,054E-03 0,0379919 ! melatonin biosynthetic process GO:0030187 7 5 0,000 5,054E-03 0,03787536 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 5,054E-03 0,03775953 ! cellular response to nutrient GO:0031670 8 5 0,000 5,054E-03 0,03764441 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 5,054E-03 0,03752999 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 5,054E-03 0,03741626 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 5,054E-03 0,03730322 ! regulation of hair follicle development GO:0051797 10 5 0,000 5,054E-03 0,03719086 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 5,054E-03 0,03707918 ! response to redox state GO:0051775 6 5 0,000 5,054E-03 0,03696816 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 5,054E-03 0,03685781 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 5,054E-03 0,03674811 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,054E-03 0,03663907 ! brown fat cell differentiation GO:0050873 7 5 0,000 5,054E-03 0,03653067 ! regulation of telomerase activity GO:0051972 7 5 0,000 5,054E-03 0,03642291 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,054E-03 0,03631578 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 5,054E-03 0,03620929 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,054E-03 0,03610341 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 5,054E-03 0,03599815 ! striatum development GO:0021756 14 5 0,000 5,054E-03 0,03589351 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 5,054E-03 0,03578947 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 5,054E-03 0,03568603 ! glial cell migration GO:0008347 10 5 0,000 5,054E-03 0,03558319 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,054E-03 0,03548094 ! neural plate morphogenesis GO:0001839 7 5 0,000 5,054E-03 0,03537927 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 5,054E-03 0,03527819 ! somatic stem cell maintenance GO:0035019 15 5 0,000 5,054E-03 0,03517768 ! T cell activation during immune response GO:0002286 9 5 0,000 5,054E-03 0,03507774 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 5,054E-03 0,03497837 ! negative regulation of lipase activity GO:0060192 8 5 0,000 5,054E-03 0,03487957 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 5,054E-03 0,03478131 ! neuroprotection GO:0043526 8 5 0,000 5,054E-03 0,03468361 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 5,054E-03 0,03458646 ! regulation of sensory perception GO:0051931 8 5 0,000 5,054E-03 0,03448985 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 5,054E-03 0,03439378 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 5,054E-03 0,03429824 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 5,054E-03 0,03420323 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 5,054E-03 0,03410875 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 5,054E-03 0,03401478 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 5,054E-03 0,03392134 ! sequestering of calcium ion GO:0051208 7 5 0,000 5,054E-03 0,0338284 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 5,054E-03 0,03373597 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 5,054E-03 0,03364405 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 5,054E-03 0,03355263 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 5,054E-03 0,0334617 ! spindle assembly GO:0051225 6 5 0,000 5,054E-03 0,03337126 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 5,054E-03 0,03328131 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 5,054E-03 0,03319184 ! protein palmitoylation GO:0018345 12 5 0,000 5,054E-03 0,03310286 ! drug metabolic process GO:0017144 7 5 0,000 5,054E-03 0,03301435 ! stem cell division GO:0017145 11 5 0,000 5,054E-03 0,03292631 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 5,054E-03 0,03283874 ! organ regeneration GO:0031100 7 5 0,000 5,054E-03 0,03275163 ! carnitine metabolic process GO:0009437 8 5 0,000 5,054E-03 0,03266499 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 5,054E-03 0,0325788 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 6,062E-03 0,0389725 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,062E-03 0,03887021 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 6,062E-03 0,03876845 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 6,062E-03 0,03866723 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 6,062E-03 0,03856653 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 6,062E-03 0,03846636 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 6,062E-03 0,03836671 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 6,062E-03 0,03826757 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 6,062E-03 0,03816894 ! response to oxygen radical GO:0000305 11 6 0,000 6,062E-03 0,03807082 ! positive regulation of axon extension GO:0045773 13 6 0,000 6,062E-03 0,0379732 ! myoblast cell fate commitment GO:0048625 18 6 0,000 6,062E-03 0,03787608 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 6,062E-03 0,03777946 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 6,062E-03 0,03768333 ! regulation of interferon-beta production GO:0032648 8 6 0,000 6,062E-03 0,03758769 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 6,062E-03 0,03749253 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 6,062E-03 0,03739785 ! forebrain regionalization GO:0021871 9 6 0,000 6,062E-03 0,03730365 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 6,062E-03 0,03720992 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 6,062E-03 0,03711666 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 6,062E-03 0,03702387 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 6,062E-03 0,03693154 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 6,062E-03 0,03683967 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 6,062E-03 0,03674826 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 6,062E-03 0,0366573 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 6,062E-03 0,03656679 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 6,062E-03 0,03647672 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 6,062E-03 0,0363871 ! malate metabolic process GO:0006108 13 6 0,000 6,062E-03 0,03629791 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 6,062E-03 0,03620916 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 6,062E-03 0,03612085 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 6,062E-03 0,03603296 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 6,062E-03 0,03594551 ! protein refolding GO:0042026 15 6 0,000 6,062E-03 0,03585847 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 6,062E-03 0,03577186 ! opsonization GO:0008228 8 6 0,000 6,062E-03 0,03568566 ! mating behavior GO:0007617 7 6 0,000 6,062E-03 0,03559988 ! erythrocyte maturation GO:0043249 8 6 0,000 6,062E-03 0,0355145 ! embryonic hemopoiesis GO:0035162 16 6 0,000 6,062E-03 0,03542954 ! protein amino acid dealkylation GO:0008214 15 6 0,000 6,062E-03 0,03534498 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 6,062E-03 0,03526083 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 6,062E-03 0,03517707 ! response to interferon-gamma GO:0034341 16 6 0,000 6,062E-03 0,03509372 ! toxin metabolic process GO:0009404 11 6 0,000 6,062E-03 0,03501075 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 6,062E-03 0,03492818 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 6,062E-03 0,034846 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 6,062E-03 0,0347642 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 6,062E-03 0,03468278 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 6,062E-03 0,03460175 ! cGMP-mediated signaling GO:0019934 14 6 0,000 6,062E-03 0,03452109 ! dorsal spinal cord development GO:0021516 10 6 0,000 6,062E-03 0,03444081 ! activation of MAPKKK activity GO:0000185 12 6 0,000 6,062E-03 0,0343609 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 6,062E-03 0,03428136 ! thymic T cell selection GO:0045061 16 6 0,000 6,062E-03 0,03420219 ! sphingoid catabolic process GO:0046521 8 6 0,000 6,062E-03 0,03412338 ! protein lipoylation GO:0009249 10 6 0,000 6,062E-03 0,03404494 ! transepithelial chloride transport GO:0030321 12 6 0,000 6,062E-03 0,03396685 GO:0070633|transepithelial transport, ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 6,062E-03 0,03388913 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 6,062E-03 0,03381175 ! glutamate catabolic process GO:0006538 12 6 0,000 6,062E-03 0,03373473 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 6,062E-03 0,03365806 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 6,062E-03 0,03358174 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 6,062E-03 0,03350577 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 6,062E-03 0,03343013 ! hyperosmotic response GO:0006972 10 6 0,000 6,062E-03 0,03335484 ! L-serine biosynthetic process GO:0006564 7 6 0,000 6,062E-03 0,03327988 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 6,062E-03 0,03320527 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 6,062E-03 0,03313098 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 6,062E-03 0,03305703 ! urea metabolic process GO:0019627 7 6 0,000 6,062E-03 0,0329834 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 6,062E-03 0,03291011 ! neutrophil activation GO:0042119 7 6 0,000 6,062E-03 0,03283714 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 6,062E-03 0,03276449 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 6,062E-03 0,03269216 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 6,062E-03 0,03262015 ! paraxial mesoderm development GO:0048339 16 6 0,000 6,062E-03 0,03254846 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 6,062E-03 0,03247708 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 6,062E-03 0,03240601 ! neuron apoptosis GO:0051402 15 6 0,000 6,062E-03 0,03233526 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 6,062E-03 0,03226481 ! T cell mediated immunity GO:0002456 17 6 0,000 6,062E-03 0,03219467 ! negative regulation of platelet activation GO:0010544 9 6 0,000 6,062E-03 0,03212483 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 6,062E-03 0,0320553 ! carnitine transport GO:0015879 10 6 0,000 6,062E-03 0,03198607 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,062E-03 0,03191713 ! positive regulation of exocytosis GO:0045921 11 6 0,000 6,062E-03 0,03184849 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 6,062E-03 0,03178015 ! early endosome to late endosome transport GO:0045022 16 6 0,000 6,062E-03 0,0317121 ! 5S class rRNA transcription GO:0042791 13 6 0,000 6,062E-03 0,03164433 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 6,062E-03 0,03157686 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 6,062E-03 0,03150968 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 6,062E-03 0,03144278 ! sodium ion homeostasis GO:0055078 12 6 0,000 6,062E-03 0,03137616 ! establishment of spindle localization GO:0051293 16 6 0,000 6,062E-03 0,03130983 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 6,062E-03 0,03124377 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 6,062E-03 0,031178 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 6,062E-03 0,0311125 ! response to UV-C GO:0010225 14 6 0,000 6,062E-03 0,03104727 ! astrocyte development GO:0014002 16 6 0,000 6,062E-03 0,03098232 ! protein targeting to lysosome GO:0006622 12 6 0,000 6,062E-03 0,03091764 ! purine base biosynthetic process GO:0009113 17 6 0,000 6,062E-03 0,03085323 ! interaction with symbiont GO:0051702 14 6 0,000 6,062E-03 0,03078908 ! regulation of dendrite development GO:0050773 16 6 0,000 6,062E-03 0,0307252 ! peptidyl-arginine modification GO:0018195 13 6 0,000 6,062E-03 0,03066159 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 6,062E-03 0,03059824 ! response to copper ion GO:0046688 10 6 0,000 6,062E-03 0,03053515 ! response to exogenous dsRNA GO:0043330 13 6 0,000 6,062E-03 0,03047232 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 6,062E-03 0,03040975 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,062E-03 0,03034744 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 6,062E-03 0,03028538 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 6,062E-03 0,03022357 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 6,062E-03 0,03016201 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,062E-03 0,03010071 ! nucleoside catabolic process GO:0009164 10 6 0,000 6,062E-03 0,03003965 ! hair follicle maturation GO:0048820 8 6 0,000 6,062E-03 0,02997884 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 6,062E-03 0,02991828 ! Schwann cell development GO:0014044 15 6 0,000 6,062E-03 0,02985796 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 6,062E-03 0,02979788 ! response to pheromone GO:0019236 6 6 0,000 6,062E-03 0,02973805 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 6,062E-03 0,02967845 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 6,062E-03 0,0296191 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 6,062E-03 0,02955998 ! base conversion or substitution editing GO:0016553 6 6 0,000 6,062E-03 0,02950109 ! subpallium development GO:0021544 15 6 0,000 6,062E-03 0,02944244 ! neural tube patterning GO:0021532 8 6 0,000 6,062E-03 0,02938402 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 6,062E-03 0,02932584 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 6,062E-03 0,02926788 ! maintenance of organ identity GO:0048496 9 6 0,000 6,062E-03 0,02921015 ! G2 phase GO:0051319 16 6 0,000 6,062E-03 0,02915265 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 6,062E-03 0,02909538 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 6,062E-03 0,02903833 ! oxygen homeostasis GO:0032364 10 6 0,000 6,062E-03 0,0289815 ! establishment of planar polarity GO:0001736 7 6 0,000 6,062E-03 0,0289249 ! regulation of mast cell activation GO:0033003 13 6 0,000 6,062E-03 0,02886852 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 6,062E-03 0,02881235 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 6,062E-03 0,0287564 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 6,062E-03 0,02870068 ! receptor internalization GO:0031623 11 6 0,000 6,062E-03 0,02864516 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 6,062E-03 0,02858986 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 6,062E-03 0,02853478 ! neutrophil homeostasis GO:0001780 11 6 0,000 6,062E-03 0,0284799 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,062E-03 0,02842524 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 6,062E-03 0,02837078 ! protein deubiquitination GO:0016579 16 6 0,000 6,062E-03 0,02831654 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 6,062E-03 0,0282625 ! protein destabilization GO:0031648 9 6 0,000 6,062E-03 0,02820866 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 6,062E-03 0,02815504 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 6,062E-03 0,02810161 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 6,062E-03 0,02804839 ! regulation of viral transcription GO:0046782 11 6 0,000 6,062E-03 0,02799537 ! progesterone metabolic process GO:0042448 12 6 0,000 6,062E-03 0,02794254 ! negative regulation of axon extension GO:0030517 24 6 0,000 6,062E-03 0,02788992 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 6,062E-03 0,0278375 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 6,062E-03 0,02778527 ! triglyceride catabolic process GO:0019433 10 6 0,000 6,062E-03 0,02773324 ! determination of adult lifespan GO:0008340 17 6 0,000 6,062E-03 0,0276814 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 6,062E-03 0,02762975 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 6,062E-03 0,0275783 ! neural plate development GO:0001840 9 6 0,000 6,062E-03 0,02752704 ! catecholamine transport GO:0051937 9 6 0,000 6,062E-03 0,02747597 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 6,062E-03 0,02742509 ! sensory cilium assembly GO:0035058 10 6 0,000 6,062E-03 0,0273744 ! organ or tissue specific immune response GO:0002251 8 6 0,000 6,062E-03 0,02732389 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 6,062E-03 0,02727357 ! maternal placenta development GO:0001893 12 6 0,000 6,062E-03 0,02722343 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 6,062E-03 0,02717348 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 6,062E-03 0,02712372 ! negative regulation of B cell activation GO:0050869 14 6 0,000 6,062E-03 0,02707413 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 6,062E-03 0,02702472 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 6,062E-03 0,0269755 ! positive regulation of coagulation GO:0050820 13 6 0,000 6,062E-03 0,02692645 ! cellular anion homeostasis GO:0030002 11 6 0,000 6,062E-03 0,02687758 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 7,069E-03 0,03128497 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 7,069E-03 0,0312284 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 7,069E-03 0,03117203 ! behavioral response to cocaine GO:0048148 14 7 0,000 7,069E-03 0,03111587 ! regulation of helicase activity GO:0051095 16 7 0,000 7,069E-03 0,0310599 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 7,069E-03 0,03100414 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 7,069E-03 0,03094858 ! sleep GO:0030431 16 7 0,000 7,069E-03 0,03089321 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 7,069E-03 0,03083805 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 7,069E-03 0,03078308 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 7,069E-03 0,0307283 ! prostate gland development GO:0030850 14 7 0,000 7,069E-03 0,03067372 ! nucleotide-sugar transport GO:0015780 11 7 0,000 7,069E-03 0,03061934 ! synaptonemal complex assembly GO:0007130 10 7 0,000 7,069E-03 0,03056514 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 7,069E-03 0,03051114 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 7,069E-03 0,03045733 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,069E-03 0,03040371 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 7,069E-03 0,03035027 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 7,069E-03 0,03029703 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 7,069E-03 0,03024397 ! SMAD protein complex assembly GO:0007183 13 7 0,000 7,069E-03 0,03019109 ! glycolipid transport GO:0046836 11 7 0,000 7,069E-03 0,0301384 ! protein amino acid sulfation GO:0006477 10 7 0,000 7,069E-03 0,0300859 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 7,069E-03 0,03003358 ! neuron adhesion GO:0007158 14 7 0,000 7,069E-03 0,02998143 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 7,069E-03 0,02992947 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 7,069E-03 0,02987769 ! establishment of tissue polarity GO:0007164 8 7 0,000 7,069E-03 0,02982609 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 7,069E-03 0,02977467 ! mRNA stabilization GO:0048255 18 7 0,000 7,069E-03 0,02972342 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 7,069E-03 0,02967235 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 7,069E-03 0,02962145 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 7,069E-03 0,02957073 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 7,069E-03 0,02952018 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 7,069E-03 0,02946981 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 7,069E-03 0,0294196 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 7,069E-03 0,02936957 ! lipoprotein transport GO:0042953 14 7 0,000 7,069E-03 0,0293197 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 7,069E-03 0,02927001 ! rhythmic behavior GO:0007622 17 7 0,000 7,069E-03 0,02922048 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 7,069E-03 0,02917112 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 7,069E-03 0,02912193 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 7,069E-03 0,02907291 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 7,069E-03 0,02902404 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 7,069E-03 0,02897535 ! regulation of odontogenesis GO:0042481 14 7 0,000 7,069E-03 0,02892681 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 7,069E-03 0,02887844 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 7,069E-03 0,02883023 ! mechanosensory behavior GO:0007638 16 7 0,000 7,069E-03 0,02878218 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 7,069E-03 0,02873429 ! positive regulation of isotype switching GO:0045830 17 7 0,000 7,069E-03 0,02868655 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 7,069E-03 0,02863898 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 7,069E-03 0,02859157 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,069E-03 0,02854431 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,069E-03 0,0284972 ! spinal cord patterning GO:0021511 14 7 0,000 7,069E-03 0,02845026 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 7,069E-03 0,02840346 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 7,069E-03 0,02835682 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 7,069E-03 0,02831034 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 7,069E-03 0,028264 ! adrenal gland development GO:0030325 17 7 0,000 7,069E-03 0,02821782 ! cysteine metabolic process GO:0006534 13 7 0,000 7,069E-03 0,02817179 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 7,069E-03 0,02812591 ! ovulation GO:0030728 10 7 0,000 7,069E-03 0,02808017 ! adenohypophysis development GO:0021984 11 7 0,000 7,069E-03 0,02803459 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 7,069E-03 0,02798915 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 7,069E-03 0,02794386 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 7,069E-03 0,02789872 ! microtubule nucleation GO:0007020 21 7 0,000 7,069E-03 0,02785372 ! proline biosynthetic process GO:0006561 10 7 0,000 7,069E-03 0,02780887 ! tryptophan metabolic process GO:0006568 11 7 0,000 7,069E-03 0,02776416 ! thyroid hormone generation GO:0006590 13 7 0,000 7,069E-03 0,02771959 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 7,069E-03 0,02767517 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 7,069E-03 0,02763089 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 7,069E-03 0,02758675 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 7,069E-03 0,02754275 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 7,069E-03 0,02749889 ! galactose metabolic process GO:0006012 13 7 0,000 7,069E-03 0,02745518 ! vesicle fusion GO:0006906 20 7 0,000 7,069E-03 0,0274116 ! response to dietary excess GO:0002021 8 7 0,000 7,069E-03 0,02736815 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 7,069E-03 0,02732485 ! intracellular pH reduction GO:0051452 13 7 0,000 7,069E-03 0,02728168 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 7,069E-03 0,02723865 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 7,069E-03 0,02719576 ! organ growth GO:0035265 15 7 0,000 7,069E-03 0,027153 ! nucleoside transport GO:0015858 11 7 0,000 7,069E-03 0,02711037 ! nucleoside salvage GO:0043174 11 7 0,000 7,069E-03 0,02706788 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 7,069E-03 0,02702552 ! male sex determination GO:0030238 15 7 0,000 7,069E-03 0,02698329 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 7,069E-03 0,02694119 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 7,069E-03 0,02689923 ! parturition GO:0007567 16 7 0,000 7,069E-03 0,0268574 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 7,069E-03 0,02681569 ! rRNA modification GO:0000154 14 7 0,000 7,069E-03 0,02677412 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 7,069E-03 0,02673267 ! spindle checkpoint GO:0031577 16 7 0,000 7,069E-03 0,02669135 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 7,069E-03 0,02665016 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 7,069E-03 0,0266091 ! monocyte differentiation GO:0030224 16 7 0,000 7,069E-03 0,02656816 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 7,069E-03 0,02652735 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 7,069E-03 0,02648667 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 7,069E-03 0,0264461 ! hyaluronan metabolic process GO:0030212 9 7 0,000 7,069E-03 0,02640567 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 7,069E-03 0,02636535 ! anterograde axon cargo transport GO:0008089 18 7 0,000 7,069E-03 0,02632516 ! fibrinolysis GO:0042730 11 7 0,000 7,069E-03 0,02628509 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 7,069E-03 0,02624515 ! skeletal muscle contraction GO:0003009 8 7 0,000 7,069E-03 0,02620532 ! eating behavior GO:0042755 8 7 0,000 7,069E-03 0,02616561 ! B cell lineage commitment GO:0002326 21 7 0,000 7,069E-03 0,02612603 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 7,069E-03 0,02608656 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 7,069E-03 0,02604722 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 7,069E-03 0,02600799 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 7,069E-03 0,02596888 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 7,069E-03 0,02592989 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 7,069E-03 0,02589101 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 7,069E-03 0,02585225 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 7,069E-03 0,02581361 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 7,069E-03 0,02577508 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 7,069E-03 0,02573667 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 7,069E-03 0,02569837 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 7,069E-03 0,02566019 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 7,069E-03 0,02562212 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 7,069E-03 0,02558416 ! histone ubiquitination GO:0016574 9 7 0,000 7,069E-03 0,02554631 ! regulation of meiosis GO:0040020 12 7 0,000 7,069E-03 0,02550858 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 7,069E-03 0,02547095 ! T cell lineage commitment GO:0002360 16 7 0,000 7,069E-03 0,02543344 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 7,069E-03 0,02539604 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 7,069E-03 0,02535875 ! membrane to membrane docking GO:0022614 14 7 0,000 7,069E-03 0,02532156 ! transcription termination GO:0006353 14 7 0,000 7,069E-03 0,02528449 ! coenzyme A metabolic process GO:0015936 12 7 0,000 7,069E-03 0,02524752 ! anaphase GO:0051322 18 7 0,000 7,069E-03 0,02521067 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 7,069E-03 0,02517392 ! axonal fasciculation GO:0007413 19 7 0,000 7,069E-03 0,02513727 ! negative regulation of nuclear division GO:0051784 15 7 0,000 7,069E-03 0,02510074 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 7,069E-03 0,0250643 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 7,069E-03 0,02502798 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 7,069E-03 0,02499176 ! diuresis GO:0030146 12 7 0,000 7,069E-03 0,02495564 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 7,069E-03 0,02491963 ! thiamin metabolic process GO:0006772 7 7 0,000 7,069E-03 0,02488373 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 7,069E-03 0,02484792 ! antibiotic transport GO:0042891 9 7 0,000 7,069E-03 0,02481222 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,069E-03 0,02477662 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 7,069E-03 0,02474113 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 7,069E-03 0,02470573 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 7,069E-03 0,02467044 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 7,069E-03 0,02463524 ! melanin biosynthetic process GO:0042438 10 7 0,000 7,069E-03 0,02460015 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 7,069E-03 0,02456516 ! dopamine biosynthetic process GO:0042416 18 7 0,000 7,069E-03 0,02453026 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 7,069E-03 0,02449547 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 7,069E-03 0,02446077 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 7,069E-03 0,02442618 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 7,069E-03 0,02439167 ! endosome to lysosome transport GO:0008333 12 7 0,000 7,069E-03 0,02435727 ! protein modification by small protein removal GO:0070646 19 7 0,000 7,069E-03 0,02432297 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 7,069E-03 0,02428876 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 7,069E-03 0,02425464 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 7,069E-03 0,02422063 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 7,069E-03 0,0241867 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 7,069E-03 0,02415288 ! muscle adaptation GO:0043500 13 7 0,000 7,069E-03 0,02411914 ! embryonic heart tube development GO:0035050 14 7 0,000 7,069E-03 0,0240855 ! retina homeostasis GO:0001895 12 7 0,000 7,069E-03 0,02405196 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 7,069E-03 0,02401851 ! protein amino acid prenylation GO:0018346 19 7 0,000 7,069E-03 0,02398515 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 7,069E-03 0,02395188 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 7,069E-03 0,02391871 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 8,075E-03 0,02728443 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 8,075E-03 0,02724674 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 8,075E-03 0,02720916 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 8,075E-03 0,02717168 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 8,075E-03 0,02713431 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 8,075E-03 0,02709703 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 8,075E-03 0,02705986 ! male meiosis GO:0007140 9 8 0,000 8,075E-03 0,0270228 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 8,075E-03 0,02698583 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 8,075E-03 0,02694896 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 8,075E-03 0,0269122 ! meiotic prophase I GO:0007128 14 8 0,000 8,075E-03 0,02687553 ! response to zinc ion GO:0010043 12 8 0,000 8,075E-03 0,02683897 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 8,075E-03 0,0268025 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 8,075E-03 0,02676613 ! oligopeptide transport GO:0006857 16 8 0,000 8,075E-03 0,02672987 ! actin-myosin filament sliding GO:0033275 13 8 0,000 8,075E-03 0,02669369 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 8,075E-03 0,02665762 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 8,075E-03 0,02662165 ! signal peptide processing GO:0006465 12 8 0,000 8,075E-03 0,02658577 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 8,075E-03 0,02654999 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 8,075E-03 0,0265143 ! macrophage chemotaxis GO:0048246 12 8 0,000 8,075E-03 0,02647871 ! succinate metabolic process GO:0006105 17 8 0,000 8,075E-03 0,02644322 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 8,075E-03 0,02640782 ! membrane hyperpolarization GO:0060081 11 8 0,000 8,075E-03 0,02637251 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 8,075E-03 0,0263373 ! estrogen metabolic process GO:0008210 17 8 0,000 8,075E-03 0,02630219 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 8,075E-03 0,02626716 ! T-helper 1 type immune response GO:0042088 12 8 0,000 8,075E-03 0,02623223 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 8,075E-03 0,0261974 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 8,075E-03 0,02616265 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 8,075E-03 0,026128 ! reflex GO:0060004 17 8 0,000 8,075E-03 0,02609344 ! endothelial cell differentiation GO:0045446 17 8 0,000 8,075E-03 0,02605897 ! glycerolipid catabolic process GO:0046503 14 8 0,000 8,075E-03 0,02602459 ! hemoglobin metabolic process GO:0020027 14 8 0,000 8,075E-03 0,0259903 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 8,075E-03 0,02595611 ! pigment granule organization GO:0048753 17 8 0,000 8,075E-03 0,025922 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 8,075E-03 0,02588798 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 8,075E-03 0,02585405 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 8,075E-03 0,02582021 ! astrocyte differentiation GO:0048708 19 8 0,000 8,075E-03 0,02578646 ! histidine catabolic process GO:0006548 10 8 0,000 8,075E-03 0,02575279 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 8,075E-03 0,02571922 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 8,075E-03 0,02568573 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 8,075E-03 0,02565233 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 8,075E-03 0,02561901 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 8,075E-03 0,02558579 ! regulation of pigmentation during development GO:0048070 25 8 0,000 8,075E-03 0,02555264 ! melanin metabolic process GO:0006582 17 8 0,000 8,075E-03 0,02551959 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 8,075E-03 0,02548662 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 8,075E-03 0,02545373 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 8,075E-03 0,02542093 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 8,075E-03 0,02538821 ! macrophage activation GO:0042116 13 8 0,000 8,075E-03 0,02535558 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 8,075E-03 0,02532303 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 8,075E-03 0,02529056 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 8,075E-03 0,02525818 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 8,075E-03 0,02522588 ! purine salvage GO:0043101 12 8 0,000 8,075E-03 0,02519367 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 8,075E-03 0,02516153 ! regulation of vascular permeability GO:0043114 12 8 0,000 8,075E-03 0,02512948 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 8,075E-03 0,02509751 ! osteoblast development GO:0002076 17 8 0,000 8,075E-03 0,02506562 ! positive regulation of vasodilation GO:0045909 14 8 0,000 8,075E-03 0,02503381 ! negative regulation of translational initiation GO:0045947 12 8 0,000 8,075E-03 0,02500208 ! Schwann cell differentiation GO:0014037 21 8 0,000 8,075E-03 0,02497043 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 8,075E-03 0,02493886 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 8,075E-03 0,02490737 ! response to UV-B GO:0010224 17 8 0,000 8,075E-03 0,02487597 ! protein targeting to vacuole GO:0006623 14 8 0,000 8,075E-03 0,02484464 ! protein retention in ER lumen GO:0006621 14 8 0,000 8,075E-03 0,02481338 ! intermediate filament organization GO:0045109 12 8 0,000 8,075E-03 0,02478221 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 8,075E-03 0,02475112 ! cellular extravasation GO:0045123 13 8 0,000 8,075E-03 0,0247201 ! cardiac muscle cell development GO:0055013 14 8 0,000 8,075E-03 0,02468916 ! response to antibiotic GO:0046677 11 8 0,000 8,075E-03 0,0246583 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 8,075E-03 0,02462752 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 8,075E-03 0,02459681 ! response to tropane GO:0014073 15 8 0,000 8,075E-03 0,02456618 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 8,075E-03 0,02453562 ! melanosome transport GO:0032402 13 8 0,000 8,075E-03 0,02450514 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 8,075E-03 0,02447474 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 8,075E-03 0,02444441 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 8,075E-03 0,02441416 ! mast cell activation GO:0045576 14 8 0,000 8,075E-03 0,02438398 ! multicellular organismal aging GO:0010259 20 8 0,000 8,075E-03 0,02435388 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 8,075E-03 0,02432385 ! gas homeostasis GO:0033483 14 8 0,000 8,075E-03 0,02429389 ! dendrite morphogenesis GO:0048813 14 8 0,000 8,075E-03 0,02426401 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 8,075E-03 0,0242342 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 8,075E-03 0,02420447 ! nucleosome disassembly GO:0006337 14 8 0,000 8,075E-03 0,0241748 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 8,075E-03 0,02414521 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 8,075E-03 0,0241157 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 8,075E-03 0,02408625 ! establishment of chromosome localization GO:0051303 14 8 0,000 8,075E-03 0,02405688 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 8,075E-03 0,02402758 ! intracellular lipid transport GO:0032365 16 8 0,000 8,075E-03 0,02399835 ! response to tumor cell GO:0002347 16 8 0,000 8,075E-03 0,02396919 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 8,075E-03 0,0239401 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 8,075E-03 0,02391108 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 8,075E-03 0,02388213 ! positive regulation of epidermis development GO:0045684 13 8 0,000 8,075E-03 0,02385325 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 8,075E-03 0,02382445 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 8,075E-03 0,02379571 ! hormone catabolic process GO:0042447 17 8 0,000 8,075E-03 0,02376704 ! glycolipid catabolic process GO:0019377 16 8 0,000 8,075E-03 0,02373844 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 8,075E-03 0,0237099 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 8,075E-03 0,02368144 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 8,075E-03 0,02365305 ! positive regulation of glucose import GO:0046326 8 8 0,000 8,075E-03 0,02362472 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 8,075E-03 0,02359646 ! adult feeding behavior GO:0008343 10 8 0,000 8,075E-03 0,02356827 ! ATP catabolic process GO:0006200 11 8 0,000 8,075E-03 0,02354014 ! blastocyst growth GO:0001832 19 8 0,000 8,075E-03 0,02351209 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 8,075E-03 0,0234841 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 8,075E-03 0,02345617 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 8,075E-03 0,02342831 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 8,075E-03 0,02340052 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 8,075E-03 0,0233728 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 8,075E-03 0,02334514 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 8,075E-03 0,02331754 ! amino sugar catabolic process GO:0046348 11 8 0,000 8,075E-03 0,02329001 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 8,075E-03 0,02326255 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 8,075E-03 0,02323515 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 8,075E-03 0,02320781 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 8,075E-03 0,02318054 ! behavioral response to nicotine GO:0035095 12 8 0,000 8,075E-03 0,02315333 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 8,075E-03 0,02312619 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 8,075E-03 0,02309911 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 8,075E-03 0,02307209 ! NAD biosynthetic process GO:0009435 17 8 0,000 8,075E-03 0,02304514 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 8,075E-03 0,02301825 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 8,075E-03 0,02299142 ! axon extension GO:0048675 16 9 0,000 9,08E-03 0,02582253 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 9,08E-03 0,02579251 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 9,08E-03 0,02576255 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 9,08E-03 0,02573266 ! pentose-phosphate shunt GO:0006098 16 9 0,000 9,08E-03 0,02570284 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 9,08E-03 0,0256731 ! cell proliferation in forebrain GO:0021846 18 9 0,000 9,08E-03 0,02564342 ! neutral lipid catabolic process GO:0046461 14 9 0,000 9,08E-03 0,0256138 ! reproductive behavior GO:0019098 22 9 0,000 9,08E-03 0,02558426 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 9,08E-03 0,02555479 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 9,08E-03 0,02552538 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 9,08E-03 0,02549604 ! UTP metabolic process GO:0046051 10 9 0,000 9,08E-03 0,02546677 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 9,08E-03 0,02543756 ! induction of positive chemotaxis GO:0050930 17 9 0,000 9,08E-03 0,02540842 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 9,08E-03 0,02537935 ! artery development GO:0060840 25 9 0,000 9,08E-03 0,02535035 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 9,08E-03 0,02532141 ! regulation of glycolysis GO:0006110 20 9 0,000 9,08E-03 0,02529254 ! cerebral cortex cell migration GO:0021795 18 9 0,000 9,08E-03 0,02526373 ! equilibrioception GO:0050957 20 9 0,000 9,08E-03 0,02523499 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 9,08E-03 0,02520631 ! chemosensory behavior GO:0007635 21 9 0,000 9,08E-03 0,0251777 ! microtubule bundle formation GO:0001578 22 9 0,000 9,08E-03 0,02514916 ! middle ear morphogenesis GO:0042474 14 9 0,000 9,08E-03 0,02512067 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 9,08E-03 0,02509226 ! leukocyte degranulation GO:0043299 16 9 0,000 9,08E-03 0,0250639 ! ganglioside metabolic process GO:0001573 22 9 0,000 9,08E-03 0,02503562 ! negative regulation of endocytosis GO:0045806 12 9 0,000 9,08E-03 0,02500739 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 9,08E-03 0,02497923 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 9,08E-03 0,02495113 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 9,08E-03 0,0249231 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 9,08E-03 0,02489512 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 9,08E-03 0,02486721 ! protein targeting to ER GO:0045047 25 9 0,000 9,08E-03 0,02483937 ! ceramide biosynthetic process GO:0046513 20 9 0,000 9,08E-03 0,02481158 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 9,08E-03 0,02478386 ! T cell selection GO:0045058 27 9 0,000 9,08E-03 0,0247562 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 9,08E-03 0,0247286 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 9,08E-03 0,02470106 ! glycine catabolic process GO:0006546 15 9 0,000 9,08E-03 0,02467359 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 9,08E-03 0,02464617 ! endosome organization GO:0007032 20 9 0,000 9,08E-03 0,02461882 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 9,08E-03 0,02459152 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 9,08E-03 0,02456429 ! regulation of type I interferon production GO:0032479 12 9 0,000 9,08E-03 0,02453712 ! mannose metabolic process GO:0006013 13 9 0,000 9,08E-03 0,02451001 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 9,08E-03 0,02448295 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 9,08E-03 0,02445596 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 9,08E-03 0,02442903 ! Rac protein signal transduction GO:0016601 20 9 0,000 9,08E-03 0,02440215 ! receptor clustering GO:0043113 20 9 0,000 9,08E-03 0,02437534 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 9,08E-03 0,02434858 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 9,08E-03 0,02432188 ! retinol metabolic process GO:0042572 20 9 0,000 9,08E-03 0,02429524 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 9,08E-03 0,02426866 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 9,08E-03 0,02424214 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 9,08E-03 0,02421567 ! macrophage differentiation GO:0030225 15 9 0,000 9,08E-03 0,02418926 ! oligodendrocyte development GO:0014003 11 9 0,000 9,08E-03 0,02416291 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 9,08E-03 0,02413662 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 9,08E-03 0,02411039 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 9,08E-03 0,02408421 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 9,08E-03 0,02405809 ! response to amine stimulus GO:0014075 13 9 0,000 9,08E-03 0,02403202 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 9,08E-03 0,02400601 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 9,08E-03 0,02398006 ! erythrocyte development GO:0048821 17 9 0,000 9,08E-03 0,02395416 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 9,08E-03 0,02392832 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 9,08E-03 0,02390254 ! renal water homeostasis GO:0003091 15 9 0,000 9,08E-03 0,02387681 ! postreplication repair GO:0006301 25 9 0,000 9,08E-03 0,02385113 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 9,08E-03 0,02382552 ! icosanoid secretion GO:0032309 15 9 0,000 9,08E-03 0,02379995 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 9,08E-03 0,02377444 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 9,08E-03 0,02374899 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 9,08E-03 0,02372359 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 9,08E-03 0,02369824 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 9,08E-03 0,02367295 ! sterol catabolic process GO:0016127 14 9 0,000 9,08E-03 0,02364771 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 9,08E-03 0,02362253 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 9,08E-03 0,0235974 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 9,08E-03 0,02357232 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 9,08E-03 0,0235473 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 9,08E-03 0,02352233 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 9,08E-03 0,02349741 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 9,08E-03 0,02347254 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 9,08E-03 0,02344773 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 9,08E-03 0,02342297 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 9,08E-03 0,02339826 ! regulation of synaptogenesis GO:0051963 15 9 0,000 9,08E-03 0,02337361 ! purine base metabolic process GO:0006144 25 9 0,000 9,08E-03 0,02334901 ! pigment granule transport GO:0051904 17 9 0,000 9,08E-03 0,02332445 ! regulation of telomere maintenance GO:0032204 17 9 0,000 9,08E-03 0,02329995 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 9,08E-03 0,0232755 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 9,08E-03 0,02325111 ! regulation of muscle adaptation GO:0043502 14 9 0,000 9,08E-03 0,02322676 ! regulation of amino acid transport GO:0051955 12 9 0,000 9,08E-03 0,02320246 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 9,08E-03 0,02317822 ! mitochondrion localization GO:0051646 18 9 0,000 9,08E-03 0,02315402 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01008352 0,02568723 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01008352 0,02566047 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01008352 0,02563377 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01008352 0,02560712 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01008352 0,02558053 ! associative learning GO:0008306 21 10 0,000 0,01008352 0,025554 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01008352 0,02552751 ! phosphate transport GO:0006817 24 10 0,000 0,01008352 0,02550109 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01008352 0,02547472 ! CTP metabolic process GO:0046036 11 10 0,000 0,01008352 0,0254484 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01008352 0,02542214 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01008352 0,02539593 ! GTP metabolic process GO:0046039 11 10 0,000 0,01008352 0,02536978 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01008352 0,02534367 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01008352 0,02531763 ! social behavior GO:0035176 29 10 0,000 0,01008352 0,02529163 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01008352 0,02526569 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01008352 0,02523981 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01008352 0,02521397 ! androgen metabolic process GO:0008209 17 10 0,000 0,01008352 0,02518819 ! phospholipid efflux GO:0033700 19 10 0,000 0,01008352 0,02516246 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01008352 0,02513679 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01008352 0,02511116 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01008352 0,02508559 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01008352 0,02506007 ! lung alveolus development GO:0048286 26 10 0,000 0,01008352 0,02503461 ! pathogenesis GO:0009405 17 10 0,000 0,01008352 0,02500919 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01008352 0,02498383 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01008352 0,02495851 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01008352 0,02493325 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01008352 0,02490804 ! endoderm development GO:0007492 18 10 0,000 0,01008352 0,02488288 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01008352 0,02485777 ! arginine catabolic process GO:0006527 17 10 0,000 0,01008352 0,02483271 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01008352 0,02480771 ! proline metabolic process GO:0006560 13 10 0,000 0,01008352 0,02478275 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01008352 0,02475784 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01008352 0,02473298 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01008352 0,02470818 ! V(D)J recombination GO:0033151 34 10 0,000 0,01008352 0,02468342 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01008352 0,02465871 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01008352 0,02463405 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01008352 0,02460944 ! B cell proliferation GO:0042100 19 10 0,000 0,01008352 0,02458488 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01008352 0,02456037 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01008352 0,02453591 ! multicellular organism growth GO:0035264 19 10 0,000 0,01008352 0,02451149 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01008352 0,02448713 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01008352 0,02446281 ! ruffle organization GO:0031529 17 10 0,000 0,01008352 0,02443854 ! epithelial cell development GO:0002064 21 10 0,000 0,01008352 0,02441432 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01008352 0,02439015 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01008352 0,02436603 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01008352 0,02434195 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01008352 0,02431792 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01008352 0,02429394 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01008352 0,02427 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01008352 0,02424611 ! motor axon guidance GO:0008045 22 10 0,000 0,01008352 0,02422227 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01008352 0,02419848 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01008352 0,02417473 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01008352 0,02415103 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01008352 0,02412738 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01008352 0,02410377 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01008352 0,02408021 ! segment specification GO:0007379 15 10 0,000 0,01008352 0,02405669 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01008352 0,02403322 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01008352 0,0240098 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01008352 0,02398642 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01008352 0,02396309 ! response to dsRNA GO:0043331 23 10 0,000 0,01008352 0,0239398 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01008352 0,02391655 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01008352 0,02389336 ! melanosome localization GO:0032400 16 10 0,000 0,01008352 0,0238702 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01008352 0,0238471 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01008352 0,02382403 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01008352 0,02380102 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01008352 0,02377804 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01008352 0,02375511 ! induction of an organ GO:0001759 17 10 0,000 0,01008352 0,02373223 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01008352 0,02370939 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01008352 0,02368659 ! protein sumoylation GO:0016925 17 10 0,000 0,01008352 0,02366383 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01008352 0,02364112 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01008352 0,02361846 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01008352 0,02359583 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01008352 0,02357326 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01008352 0,02355072 ! salivary gland development GO:0007431 28 10 0,000 0,01008352 0,02352822 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01008352 0,02350577 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01008352 0,02348337 ! midbrain development GO:0030901 14 10 0,000 0,01008352 0,023461 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01008352 0,02343868 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01008352 0,0234164 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01008352 0,02339416 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01008352 0,02337197 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01008352 0,02334981 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01008352 0,0233277 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01008352 0,02330563 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01008352 0,0232836 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01008352 0,02326162 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01008352 0,02323967 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01008352 0,02321777 ! blastocyst formation GO:0001825 18 10 0,000 0,01008352 0,02319591 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01008352 0,02317408 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01008352 0,0231523 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01008352 0,02313056 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01008352 0,02310887 ! response to nicotine GO:0035094 20 10 0,000 0,01008352 0,02308721 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01008352 0,02306559 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01008352 0,02304401 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01108642 0,02531227 ! respiratory burst GO:0045730 17 11 0,000 0,01108642 0,02528864 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01108642 0,02526505 ! neuron fate specification GO:0048665 18 11 0,000 0,01108642 0,0252415 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01108642 0,025218 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01108642 0,02519454 ! thyroid gland development GO:0030878 26 11 0,000 0,01108642 0,02517113 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01108642 0,02514776 ! synapsis GO:0007129 14 11 0,000 0,01108642 0,02512443 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01108642 0,02510114 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01108642 0,0250779 ! response to pain GO:0048265 27 11 0,000 0,01108642 0,0250547 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01108642 0,02503155 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01108642 0,02500843 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01108642 0,02498536 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01108642 0,02496233 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01108642 0,02493935 ! bone resorption GO:0045453 16 11 0,000 0,01108642 0,02491641 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01108642 0,0248935 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01108642 0,02487065 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01108642 0,02484783 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01108642 0,02482505 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01108642 0,02480232 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01108642 0,02477963 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01108642 0,02475698 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01108642 0,02473437 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01108642 0,0247118 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01108642 0,02468927 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01108642 0,02466679 ! UV protection GO:0009650 20 11 0,000 0,01108642 0,02464434 ! adult heart development GO:0007512 16 11 0,000 0,01108642 0,02462194 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01108642 0,02459958 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01108642 0,02457725 ! macroautophagy GO:0016236 19 11 0,000 0,01108642 0,02455497 ! temperature homeostasis GO:0001659 18 11 0,000 0,01108642 0,02453273 ! behavioral fear response GO:0001662 27 11 0,000 0,01108642 0,02451053 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01108642 0,02448837 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01108642 0,02446624 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01108642 0,02444416 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01108642 0,02442212 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01108642 0,02440012 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01108642 0,02437816 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01108642 0,02435623 ! regulation of organ growth GO:0046620 14 11 0,000 0,01108642 0,02433435 ! pigment granule localization GO:0051875 20 11 0,000 0,01108642 0,02431251 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01108642 0,0242907 ! vasoconstriction GO:0042310 20 11 0,000 0,01108642 0,02426894 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01108642 0,02424721 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01108642 0,02422552 ! embryonic axis specification GO:0000578 19 11 0,000 0,01108642 0,02420387 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01108642 0,02418226 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01108642 0,02416069 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01108642 0,02413916 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01108642 0,02411766 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01108642 0,0240962 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01108642 0,02407478 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01108642 0,0240534 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01108642 0,02403206 ! prophase GO:0051324 17 11 0,000 0,01108642 0,02401076 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01108642 0,02398949 ! nucleosome positioning GO:0016584 15 11 0,000 0,01108642 0,02396826 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01108642 0,02394707 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01108642 0,02392591 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01108642 0,02390479 ! apical protein localization GO:0045176 18 11 0,000 0,01108642 0,02388371 ! acid secretion GO:0046717 20 11 0,000 0,01108642 0,02386267 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01108642 0,02384167 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01108642 0,0238207 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01108642 0,02379976 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01108642 0,02377887 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01108642 0,02375801 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01108642 0,02373719 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01108642 0,0237164 ! cholesterol efflux GO:0033344 21 11 0,000 0,01108642 0,02369565 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01108642 0,02367494 ! oocyte development GO:0048599 20 11 0,000 0,01108642 0,02365426 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01108642 0,02363362 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01108642 0,02361302 ! embryonic gut development GO:0048566 19 11 0,000 0,01108642 0,02359245 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01108642 0,02357192 ! activation of innate immune response GO:0002218 16 11 0,000 0,01108642 0,02355142 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01108642 0,02353096 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01108642 0,02351053 ! lysogeny GO:0030069 22 11 0,000 0,01108642 0,02349014 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01108642 0,02346979 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01108642 0,02344947 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01108642 0,02342918 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01108642 0,02340893 ! nucleus localization GO:0051647 22 11 0,000 0,01108642 0,02338872 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01208833 0,02548041 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01208833 0,02545845 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01208833 0,02543652 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01208833 0,02541463 ! virus-host interaction GO:0019048 30 12 0,000 0,01208833 0,02539278 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01208833 0,02537096 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01208833 0,02534918 ! protein complex disassembly GO:0043241 28 12 0,000 0,01208833 0,02532744 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01208833 0,02530574 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01208833 0,02528408 ! hippocampus development GO:0021766 29 12 0,000 0,01208833 0,02526245 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01208833 0,02524085 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01208833 0,0252193 ! T cell proliferation GO:0042098 32 12 0,000 0,01208833 0,02519778 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01208833 0,0251763 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01208833 0,02515486 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01208833 0,02513345 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01208833 0,02511207 ! drug transport GO:0015893 16 12 0,000 0,01208833 0,02509074 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01208833 0,02506944 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01208833 0,02504818 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01208833 0,02502695 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01208833 0,02500576 ! focal adhesion formation GO:0048041 37 12 0,000 0,01208833 0,0249846 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01208833 0,02496348 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01208833 0,0249424 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01208833 0,02492135 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01208833 0,02490034 ! lipid digestion GO:0044241 21 12 0,000 0,01208833 0,02487936 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01208833 0,02485842 ! entry into host cell GO:0030260 34 12 0,000 0,01208833 0,02483751 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01208833 0,02481664 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01208833 0,0247958 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01208833 0,024775 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01208833 0,02475423 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01208833 0,0247335 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01208833 0,0247128 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01208833 0,02469214 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01208833 0,02467151 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01208833 0,02465092 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01208833 0,02463036 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01208833 0,02460983 ! cranial nerve development GO:0021545 23 12 0,000 0,01208833 0,02458934 ! fucose catabolic process GO:0019317 25 12 0,000 0,01208833 0,02456889 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01208833 0,02454846 ! histone acetylation GO:0016573 27 12 0,000 0,01208833 0,02452807 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01208833 0,02450772 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01208833 0,0244874 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01208833 0,02446711 ! zymogen activation GO:0031638 18 12 0,000 0,01208833 0,02444685 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01208833 0,02442663 ! T cell homeostasis GO:0043029 28 12 0,000 0,01208833 0,02440645 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01208833 0,02438629 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01208833 0,02436617 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01208833 0,02434608 ! oocyte differentiation GO:0009994 21 12 0,000 0,01208833 0,02432603 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01208833 0,02430601 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01208833 0,02428602 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01208833 0,02426606 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01208833 0,02424614 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01208833 0,02422625 ! defense response to fungus GO:0050832 15 12 0,000 0,01208833 0,02420639 ! developmental induction GO:0031128 22 12 0,000 0,01208833 0,02418657 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01208833 0,02416678 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01208833 0,02414702 ! response to cold GO:0009409 17 12 0,000 0,01208833 0,02412729 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01208833 0,02410759 ! localization within membrane GO:0051668 26 12 0,000 0,01208833 0,02408793 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01308926 0,02606117 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01308926 0,02603995 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01308926 0,02601876 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01308926 0,02599761 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01308926 0,02597649 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01308926 0,0259554 ! peroxisomal transport GO:0043574 28 13 0,000 0,01308926 0,02593435 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01308926 0,02591334 ! cartilage condensation GO:0001502 22 13 0,000 0,01308926 0,02589235 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01308926 0,0258714 ! organelle fusion GO:0048284 36 13 0,000 0,01308926 0,02585049 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01308926 0,02582961 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01308926 0,02580876 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01308926 0,02578795 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01308926 0,02576717 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01308926 0,02574642 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01308926 0,02572571 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01308926 0,02570503 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01308926 0,02568438 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01308926 0,02566377 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01308926 0,02564319 ! methionine metabolic process GO:0006555 31 13 0,000 0,01308926 0,02562264 ! plasma membrane organization GO:0007009 27 13 0,000 0,01308926 0,02560213 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01308926 0,02558165 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01308926 0,0255612 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01308926 0,02554078 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01308926 0,0255204 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01308926 0,02550005 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01308926 0,02547973 ! exocrine system development GO:0035272 34 13 0,000 0,01308926 0,02545944 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01308926 0,02543919 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01308926 0,02541896 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01308926 0,02539877 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01308926 0,02537862 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01308926 0,02535849 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01308926 0,0253384 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01308926 0,02531833 ! protein homotetramerization GO:0051289 24 13 0,000 0,01308926 0,0252983 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01308926 0,02527831 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01308926 0,02525834 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01308926 0,0252384 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01308926 0,0252185 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01308926 0,02519863 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01308926 0,02517878 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01308926 0,02515897 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01308926 0,0251392 ! histone methylation GO:0016571 29 13 0,000 0,01308926 0,02511945 ! chromatin silencing GO:0006342 29 13 0,000 0,01308926 0,02509973 ! gland morphogenesis GO:0022612 31 13 0,000 0,01308926 0,02508004 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01308926 0,02506039 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01308926 0,02504076 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01308926 0,02502117 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01308926 0,02500161 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01308926 0,02498208 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01308926 0,02496257 ! spleen development GO:0048536 24 13 0,000 0,01308926 0,0249431 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01308926 0,02492366 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01308926 0,02490425 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01308926 0,02488487 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01308926 0,02486552 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01308926 0,0248462 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01308926 0,02482691 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01308926 0,02480765 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01308926 0,02478842 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01308926 0,02476921 ! insulin secretion GO:0030073 24 13 0,000 0,01308926 0,02475004 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01308926 0,0247309 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01308926 0,02471179 ! acrosome reaction GO:0007340 19 13 0,000 0,01308926 0,02469271 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01308926 0,02467365 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01308926 0,02465463 ! rRNA transcription GO:0009303 28 14 0,000 0,0140892 0,02651765 ! regulation of S phase GO:0033261 26 14 0,000 0,0140892 0,02649723 ! water transport GO:0006833 21 14 0,000 0,0140892 0,02647685 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,0140892 0,0264565 ! non-recombinational repair GO:0000726 29 14 0,000 0,0140892 0,02643618 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,0140892 0,02641589 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,0140892 0,02639563 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,0140892 0,02637541 ! RNA polyadenylation GO:0043631 32 14 0,000 0,0140892 0,02635521 ! lipid localization GO:0010876 32 14 0,000 0,0140892 0,02633505 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,0140892 0,02631491 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,0140892 0,02629481 ! regulated secretory pathway GO:0045055 24 14 0,000 0,0140892 0,02627474 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,0140892 0,02625469 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,0140892 0,02623468 ! arginine metabolic process GO:0006525 21 14 0,000 0,0140892 0,0262147 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,0140892 0,02619475 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,0140892 0,02617483 ! regulation of heart rate GO:0002027 25 14 0,000 0,0140892 0,02615494 ! fear response GO:0042596 34 14 0,000 0,0140892 0,02613508 ! organic alcohol transport GO:0015850 29 14 0,000 0,0140892 0,02611525 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,0140892 0,02609545 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,0140892 0,02607569 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0140892 0,02605595 ! neutral amino acid transport GO:0015804 28 14 0,000 0,0140892 0,02603624 ! bone mineralization GO:0030282 18 14 0,000 0,0140892 0,02601656 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,0140892 0,02599691 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,0140892 0,02597729 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,0140892 0,0259577 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,0140892 0,02593813 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,0140892 0,0259186 ! regulation of cellular pH GO:0030641 27 14 0,000 0,0140892 0,0258991 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,0140892 0,02587963 ! ribosome assembly GO:0042255 18 14 0,000 0,0140892 0,02586018 ! cerebellum development GO:0021549 23 14 0,000 0,0140892 0,02584077 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,0140892 0,02582138 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,0140892 0,02580203 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,0140892 0,0257827 ! response to gamma radiation GO:0010332 30 14 0,000 0,0140892 0,0257634 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,0140892 0,02574413 ! NADP metabolic process GO:0006739 24 14 0,000 0,0140892 0,02572489 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,0140892 0,02570568 ! oxygen transport GO:0015671 22 14 0,000 0,0140892 0,0256865 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0140892 0,02566734 ! male genitalia development GO:0030539 26 14 0,000 0,0140892 0,02564821 ! regulation of RNA stability GO:0043487 33 14 0,000 0,0140892 0,02562912 ! regulation of axon extension GO:0030516 43 14 0,000 0,0140892 0,02561005 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,0140892 0,02559101 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,0140892 0,02557199 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,0140892 0,02555301 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01508815 0,02734447 ! lactation GO:0007595 30 15 0,000 0,01508815 0,0273242 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01508815 0,02730396 ! reproductive cellular process GO:0048610 22 15 0,000 0,01508815 0,02728375 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01508815 0,02726357 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01508815 0,02724342 ! superoxide anion generation GO:0042554 22 15 0,000 0,01508815 0,0272233 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01508815 0,02720321 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01508815 0,02718315 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01508815 0,02716311 ! copper ion transport GO:0006825 22 15 0,000 0,01508815 0,02714311 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01508815 0,02712314 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01508815 0,0271032 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01508815 0,02708328 ! sulfate transport GO:0008272 27 15 0,000 0,01508815 0,0270634 ! response to cAMP GO:0051591 25 15 0,000 0,01508815 0,02704354 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01508815 0,02702371 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01508815 0,02700392 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01508815 0,02698415 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01508815 0,02696441 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01508815 0,0269447 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01508815 0,02692502 ! vesicle coating GO:0006901 38 15 0,000 0,01508815 0,02690536 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01508815 0,02688574 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01508815 0,02686614 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01508815 0,02684657 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01508815 0,02682703 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01508815 0,02680752 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01508815 0,02678804 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01508815 0,02676859 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01508815 0,02674916 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01508815 0,02672976 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01508815 0,0267104 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01508815 0,02669105 ! histone deacetylation GO:0016575 24 15 0,000 0,01508815 0,02667174 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01508815 0,02665246 ! water homeostasis GO:0030104 28 15 0,000 0,01508815 0,0266332 ! cofactor transport GO:0051181 30 15 0,000 0,01508815 0,02661397 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01508815 0,02659477 ! muscle maintenance GO:0046716 26 15 0,000 0,01508815 0,02657559 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01508815 0,02655645 ! intestinal absorption GO:0050892 31 15 0,000 0,01508815 0,02653733 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01508815 0,02651823 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01508815 0,02649917 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01508815 0,02648013 ! cell killing GO:0001906 32 15 0,000 0,01508815 0,02646112 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01508815 0,02644214 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01508815 0,02642319 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01508815 0,02640426 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01508815 0,02638536 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01508815 0,02636648 ! actin filament polymerization GO:0030041 27 15 0,000 0,01508815 0,02634764 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01508815 0,02632882 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,01608612 0,02805024 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01608612 0,02803023 ! positive regulation of cell size GO:0045793 29 16 0,000 0,01608612 0,02801025 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01608612 0,0279903 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01608612 0,02797038 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01608612 0,02795049 ! bone remodeling GO:0046849 28 16 0,000 0,01608612 0,02793062 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01608612 0,02791078 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01608612 0,02789097 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01608612 0,02787119 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01608612 0,02785144 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01608612 0,02783172 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01608612 0,02781202 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01608612 0,02779235 ! startle response GO:0001964 28 16 0,000 0,01608612 0,02777271 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01608612 0,0277531 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01608612 0,02773351 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01608612 0,02771395 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01608612 0,02769442 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01608612 0,02767492 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01608612 0,02765544 ! pituitary gland development GO:0021983 30 16 0,000 0,01608612 0,02763599 ! response to osmotic stress GO:0006970 27 16 0,000 0,01608612 0,02761657 ! lysosomal transport GO:0007041 31 16 0,000 0,01608612 0,02759718 ! L-amino acid transport GO:0015807 33 16 0,000 0,01608612 0,02757781 ! stem cell development GO:0048864 46 16 0,000 0,01608612 0,02755847 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01608612 0,02753916 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01608612 0,02751988 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01608612 0,02750062 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01608612 0,02748139 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01608612 0,02746218 ! axon cargo transport GO:0008088 46 16 0,000 0,01608612 0,027443 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01608612 0,02742385 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01608612 0,02740473 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01608612 0,02738563 ! DNA replication initiation GO:0006270 28 16 0,000 0,01608612 0,02736656 ! neuron recognition GO:0008038 40 16 0,000 0,01608612 0,02734752 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01608612 0,0273285 ! tissue regeneration GO:0042246 27 16 0,000 0,01608612 0,02730951 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01608612 0,02729054 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01608612 0,02727161 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01608612 0,02725269 ! biomineral formation GO:0031214 22 16 0,000 0,01608612 0,02723381 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01608612 0,02721495 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01608612 0,02719611 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01608612 0,02717731 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01608612 0,02715852 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01608612 0,02713977 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01608612 0,02712104 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01608612 0,02710233 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01608612 0,02708365 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01608612 0,027065 ! peptide hormone processing GO:0016486 27 16 0,000 0,01608612 0,02704638 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,0170831 0,0287029 ! metencephalon development GO:0022037 32 17 0,000 0,0170831 0,02868317 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,0170831 0,02866347 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,0170831 0,0286438 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,0170831 0,02862416 ! signal complex assembly GO:0007172 47 17 0,000 0,0170831 0,02860454 ! filopodium assembly GO:0046847 42 17 0,000 0,0170831 0,02858494 ! endothelial cell migration GO:0043542 31 17 0,000 0,0170831 0,02856538 ! gene silencing by RNA GO:0031047 38 17 0,000 0,0170831 0,02854584 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,0170831 0,02852633 ! glial cell development GO:0021782 28 17 0,000 0,0170831 0,02850684 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,0170831 0,02848738 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,0170831 0,02846795 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,0170831 0,02844855 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,0170831 0,02842917 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,0170831 0,02840982 ! myoblast differentiation GO:0045445 50 17 0,000 0,0170831 0,02839049 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,0170831 0,02837119 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,0170831 0,02835191 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,0170831 0,02833267 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,0170831 0,02831345 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,0170831 0,02829425 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,0170831 0,02827508 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,0170831 0,02825594 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,0170831 0,02823682 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,0170831 0,02821773 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,0170831 0,02819866 ! regulation of protein binding GO:0043393 33 17 0,000 0,0170831 0,02817962 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,0170831 0,02816061 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,0170831 0,02814162 ! genitalia development GO:0048806 32 17 0,000 0,0170831 0,02812265 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,0170831 0,02810372 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,0170831 0,0280848 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,0170831 0,02806592 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,0170831 0,02804706 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,0170831 0,02802822 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,0170831 0,02800941 ! steroid catabolic process GO:0006706 34 17 0,000 0,0170831 0,02799062 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,0170831 0,02797186 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,0170831 0,02795313 ! gas transport GO:0015669 26 17 0,000 0,0170831 0,02793442 ! organic cation transport GO:0015695 32 17 0,000 0,0170831 0,02791573 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,0170831 0,02789707 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,0170831 0,02787844 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,0170831 0,02785983 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,01807911 0,02946448 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,01807911 0,02944484 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,01807911 0,02942522 ! limbic system development GO:0021761 40 18 0,000 0,01807911 0,02940563 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01807911 0,02938606 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,01807911 0,02936653 ! adult walking behavior GO:0007628 36 18 0,000 0,01807911 0,02934701 ! patterning of blood vessels GO:0001569 43 18 0,000 0,01807911 0,02932753 ! heart looping GO:0001947 34 18 0,000 0,01807911 0,02930807 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,01807911 0,02928863 ! centrosome cycle GO:0007098 26 18 0,000 0,01807911 0,02926922 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,01807911 0,02924984 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,01807911 0,02923048 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,01807911 0,02921115 ! glycine metabolic process GO:0006544 30 18 0,000 0,01807911 0,02919184 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01807911 0,02917256 ! response to retinoic acid GO:0032526 31 18 0,000 0,01807911 0,0291533 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,01807911 0,02913407 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,01807911 0,02911487 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,01807911 0,02909569 ! DNA integration GO:0015074 32 18 0,000 0,01807911 0,02907653 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,01807911 0,0290574 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,01807911 0,0290383 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,01807911 0,02901922 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,01807911 0,02900017 ! neural crest cell migration GO:0001755 41 18 0,000 0,01807911 0,02898114 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,01807911 0,02896213 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,01807911 0,02894316 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,01807911 0,0289242 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,01807911 0,02890527 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,01807911 0,02888637 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,01807911 0,02886749 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,01807911 0,02884863 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,01807911 0,0288298 ! detection of bacterium GO:0016045 22 18 0,000 0,01807911 0,02881099 ! nerve development GO:0021675 34 18 0,000 0,01807911 0,02879221 ! defense response to virus GO:0051607 43 18 0,000 0,01807911 0,02877346 ! microspike assembly GO:0030035 46 18 0,000 0,01807911 0,02875472 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,01807911 0,02873601 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,01807911 0,02871733 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,01907413 0,03027816 ! positive regulation of translation GO:0045727 31 19 0,000 0,01907413 0,0302585 ! negative regulation of defense response GO:0031348 27 19 0,000 0,01907413 0,03023887 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,01907413 0,03021926 ! neuron maturation GO:0042551 46 19 0,000 0,01907413 0,03019967 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,01907413 0,03018011 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,01907413 0,03016058 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,01907413 0,03014107 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,01907413 0,03012159 ! inositol metabolic process GO:0006020 33 19 0,000 0,01907413 0,03010213 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01907413 0,03008269 ! memory GO:0007613 34 19 0,000 0,01907413 0,03006329 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,01907413 0,0300439 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,01907413 0,03002454 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,01907413 0,03000521 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,01907413 0,0299859 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,01907413 0,02996662 ! cerebral cortex development GO:0021987 40 19 0,000 0,01907413 0,02994736 ! pigmentation during development GO:0048066 42 19 0,000 0,01907413 0,02992813 ! response to vitamin A GO:0033189 32 19 0,000 0,01907413 0,02990892 ! heme metabolic process GO:0042168 40 19 0,000 0,01907413 0,02988973 ! neuromuscular junction development GO:0007528 43 19 0,000 0,01907413 0,02987057 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,01907413 0,02985144 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,01907413 0,02983233 ! response to fungus GO:0009620 26 19 0,000 0,01907413 0,02981324 ! peptide cross-linking GO:0018149 39 19 0,000 0,01907413 0,02979418 ! protein export from nucleus GO:0006611 40 19 0,000 0,01907413 0,02977514 ! heart process GO:0003015 32 19 0,000 0,01907413 0,02975613 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,01907413 0,02973714 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,01907413 0,02971817 ! cellular pigmentation GO:0033059 37 19 0,000 0,01907413 0,02969923 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,01907413 0,02968031 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,01907413 0,02966142 ! vitamin transport GO:0051180 31 19 0,000 0,01907413 0,02964255 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,01907413 0,02962371 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,01907413 0,02960489 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,01907413 0,02958609 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,01907413 0,02956732 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,01907413 0,02954857 ! cilium assembly GO:0042384 38 19 0,000 0,01907413 0,02952984 ! peptide hormone secretion GO:0030072 32 19 0,000 0,01907413 0,02951114 ! protein secretion GO:0009306 45 20 0,000 0,02006817 0,03102945 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02006817 0,03100983 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02006817 0,03099023 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02006817 0,03097065 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02006817 0,0309511 ! skin development GO:0043588 42 20 0,000 0,02006817 0,03093157 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,02006817 0,03091207 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02006817 0,03089259 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02006817 0,03087313 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02006817 0,0308537 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,02006817 0,0308343 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02006817 0,03081492 ! response to vitamin GO:0033273 36 20 0,000 0,02006817 0,03079556 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02006817 0,03077623 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,02006817 0,03075692 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02006817 0,03073764 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02006817 0,03071838 ! response to alkaloid GO:0043279 38 20 0,000 0,02006817 0,03069915 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02006817 0,03067994 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02006817 0,03066075 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,02006817 0,03064159 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02006817 0,03062245 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02006817 0,03060333 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,02006817 0,03058424 ! actin filament bundle formation GO:0051017 47 20 0,000 0,02006817 0,03056517 ! body fluid secretion GO:0007589 33 20 0,000 0,02006817 0,03054613 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02006817 0,03052711 ! peptide secretion GO:0002790 38 20 0,000 0,02006817 0,03050811 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02006817 0,03048914 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,02006817 0,03047019 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02006817 0,03045127 ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02006817 0,03043236 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02006817 0,03041348 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02006817 0,03039463 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02006817 0,0303758 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02006817 0,03035699 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02006817 0,0303382 ! regulation of glucose import GO:0046324 30 20 0,000 0,02006817 0,03031944 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02006817 0,0303007 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02006817 0,03028199 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02006817 0,03026329 ! negative regulation of translation GO:0017148 32 20 0,000 0,02006817 0,03024463 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02006817 0,03022598 ! regulation of cell killing GO:0031341 46 21 0,000 0,02106123 0,03170215 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02106123 0,03168263 ! hormone secretion GO:0046879 39 21 0,000 0,02106123 0,03166313 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02106123 0,03164366 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02106123 0,03162421 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02106123 0,03160478 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02106123 0,03158538 ! ovarian follicle development GO:0001541 39 21 0,000 0,02106123 0,03156601 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02106123 0,03154665 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02106123 0,03152732 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02106123 0,03150801 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02106123 0,03148873 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02106123 0,03146947 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02106123 0,03145024 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02106123 0,03143103 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02106123 0,03141184 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02106123 0,03139267 ! sensory perception of pain GO:0019233 33 21 0,000 0,02106123 0,03137353 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02106123 0,03135441 ! diencephalon development GO:0021536 36 21 0,000 0,02106123 0,03133532 ! collagen fibril organization GO:0030199 62 21 0,000 0,02106123 0,03131624 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02106123 0,03129719 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02106123 0,03127817 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02106123 0,03125917 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02106123 0,03124019 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02106123 0,03122123 ! collagen catabolic process GO:0030574 29 21 0,000 0,02106123 0,0312023 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02106123 0,03118339 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02106123 0,0311645 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02106123 0,03114563 ! actin filament-based movement GO:0030048 47 21 0,000 0,02106123 0,03112679 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02106123 0,03110797 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02205332 0,03255363 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02205332 0,03253397 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02205332 0,03251433 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02205332 0,03249472 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,02205332 0,03247514 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02205332 0,03245557 ! microtubule-based transport GO:0010970 59 22 0,000 0,02205332 0,03243603 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02205332 0,03241652 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02205332 0,03239702 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,02205332 0,03237755 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,02205332 0,03235811 ! cellular response to starvation GO:0009267 37 22 0,000 0,02205332 0,03233869 ! vacuolar transport GO:0007034 41 22 0,000 0,02205332 0,03231929 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02205332 0,03229991 ! fucose metabolic process GO:0006004 44 22 0,000 0,02205332 0,03228056 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,02205332 0,03226123 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02205332 0,03224192 ! ureteric bud development GO:0001657 50 22 0,000 0,02205332 0,03222264 ! stem cell differentiation GO:0048863 57 22 0,000 0,02205332 0,03220338 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02205332 0,03218414 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02205332 0,03216493 ! cytolysis GO:0019835 27 22 0,000 0,02205332 0,03214573 ! renal system process GO:0003014 42 22 0,000 0,02205332 0,03212656 ! vasodilation GO:0042311 40 22 0,000 0,02205332 0,03210742 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02205332 0,0320883 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02205332 0,0320692 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,02205332 0,03205012 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02205332 0,03203106 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02205332 0,03201203 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,02205332 0,03199302 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,02205332 0,03197404 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02205332 0,03195507 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02205332 0,03193613 ! sarcomere organization GO:0045214 32 22 0,000 0,02205332 0,03191721 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02205332 0,03189831 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02205332 0,03187944 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02205332 0,03186059 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02205332 0,03184175 ! gut development GO:0048565 44 22 0,000 0,02205332 0,03182295 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02205332 0,03180416 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,02205332 0,0317854 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02205332 0,03176666 ! protein stabilization GO:0050821 41 22 0,000 0,02205332 0,03174794 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,02304442 0,0331552 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,02304442 0,03313568 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,02304442 0,03311619 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,02304442 0,03309672 ! gluconeogenesis GO:0006094 38 23 0,000 0,02304442 0,03307728 ! glycerol metabolic process GO:0006071 40 23 0,000 0,02304442 0,03305785 ! viral genome replication GO:0019079 44 23 0,000 0,02304442 0,03303845 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,02304442 0,03301907 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,02304442 0,03299972 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,02304442 0,03298039 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,02304442 0,03296108 ! regeneration GO:0031099 42 23 0,000 0,02304442 0,03294179 ! axis specification GO:0009798 43 23 0,000 0,02304442 0,03292253 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,02304442 0,03290329 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,02304442 0,03288407 ! response to ethanol GO:0045471 47 23 0,000 0,02304442 0,03286487 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,02304442 0,0328457 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,02304442 0,03282654 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,02304442 0,03280741 ! peroxisome organization GO:0007031 43 23 0,000 0,02304442 0,03278831 ! lysosome organization GO:0007040 47 23 0,000 0,02304442 0,03276922 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,02304442 0,03275016 ! vesicle targeting GO:0006903 49 23 0,000 0,02304442 0,03273112 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,02304442 0,0327121 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,02304442 0,0326931 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,02304442 0,03267413 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,02304442 0,03265518 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,02304442 0,03263624 ! DNA modification GO:0006304 36 23 0,000 0,02304442 0,03261734 ! fatty acid transport GO:0015908 47 23 0,000 0,02304442 0,03259845 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,02304442 0,03257958 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,02304442 0,03256074 ! hormone transport GO:0009914 41 23 0,000 0,02304442 0,03254192 ! cell-cell recognition GO:0009988 28 23 0,000 0,02304442 0,03252312 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,02304442 0,03250434 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,02304442 0,03248559 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,02304442 0,03246685 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,02403455 0,03384231 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,02403455 0,03382282 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,02403455 0,03380334 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,02403455 0,03378389 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,02403455 0,03376447 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,02403455 0,03374506 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,02403455 0,03372568 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,02403455 0,03370632 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,02403455 0,03368698 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,02403455 0,03366767 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,02403455 0,03364837 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,02403455 0,0336291 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,02403455 0,03360985 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,02403455 0,03359062 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,02403455 0,03357142 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,02403455 0,03355223 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,02403455 0,03353307 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,02403455 0,03351393 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,02403455 0,03349481 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,02403455 0,03347572 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,02403455 0,03345664 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,02403455 0,03343759 ! membrane depolarization GO:0051899 45 24 0,000 0,02403455 0,03341856 ! pallium development GO:0021543 56 24 0,000 0,02403455 0,03339955 ! oogenesis GO:0048477 44 24 0,000 0,02403455 0,03338056 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,02403455 0,0333616 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,02403455 0,03334265 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,02403455 0,03332373 ! platelet activation GO:0030168 41 24 0,000 0,02403455 0,03330483 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,02403455 0,03328595 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,02403455 0,03326709 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,02403455 0,03324825 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,02403455 0,03322943 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,02403455 0,03321064 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,02403455 0,03319187 ! regulation of amine transport GO:0051952 41 24 0,000 0,02403455 0,03317311 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,02403455 0,03315438 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02502371 0,03449939 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02502371 0,03447993 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02502371 0,03446049 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02502371 0,03444108 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02502371 0,03442169 ! phototransduction GO:0007602 37 25 0,000 0,02502371 0,03440231 ! keratinization GO:0031424 37 25 0,000 0,02502371 0,03438297 ! vasculogenesis GO:0001570 49 25 0,000 0,02502371 0,03436364 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,02502371 0,03434433 ! vacuole organization GO:0007033 49 25 0,000 0,02502371 0,03432505 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02502371 0,03430579 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02502371 0,03428655 ! receptor metabolic process GO:0043112 53 25 0,000 0,02502371 0,03426733 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02502371 0,03424813 ! regulation of behavior GO:0050795 48 25 0,000 0,02502371 0,03422895 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02502371 0,0342098 ! interaction with host GO:0051701 66 25 0,000 0,02502371 0,03419067 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02502371 0,03417156 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02502371 0,03415247 ! immunoglobulin production GO:0002377 62 25 0,000 0,02502371 0,0341334 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02502371 0,03411435 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,02502371 0,03409532 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02502371 0,03407632 ! liver development GO:0001889 55 25 0,000 0,02502371 0,03405733 ! protein tetramerization GO:0051262 57 25 0,000 0,02502371 0,03403837 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,02601189 0,03536285 ! myelination GO:0042552 50 26 0,000 0,02601189 0,03534318 ! initiation of viral infection GO:0019059 60 26 0,000 0,02601189 0,03532353 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,02601189 0,03530391 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,02601189 0,03528431 ! molting cycle process GO:0022404 52 26 0,000 0,02601189 0,03526473 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,02601189 0,03524517 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,02601189 0,03522563 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,02601189 0,03520611 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,02601189 0,03518662 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,02601189 0,03516715 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,02601189 0,0351477 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,02601189 0,03512827 ! digestive system process GO:0022600 49 26 0,000 0,02601189 0,03510886 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,02601189 0,03508947 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,02601189 0,03507011 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,02601189 0,03505076 ! neural crest cell development GO:0014032 59 26 0,000 0,02601189 0,03503144 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,02601189 0,03501214 ! negative regulation of cell development GO:0010721 83 26 0,000 0,02601189 0,03499286 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,02601189 0,0349736 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,02601189 0,03495436 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,02601189 0,03493515 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,02601189 0,03491595 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,02601189 0,03489678 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,02601189 0,03487763 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,02601189 0,03485849 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,02601189 0,03483938 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,02601189 0,03482029 ! blastocyst development GO:0001824 50 26 0,000 0,02601189 0,03480122 ! telomere organization GO:0032200 46 26 0,000 0,02601189 0,03478218 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,02601189 0,03476315 ! neural tube closure GO:0001843 58 26 0,000 0,02601189 0,03474414 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,02601189 0,03472516 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,02601189 0,03470619 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02699909 0,0360037 ! embryonic pattern specification GO:0009880 49 27 0,000 0,02699909 0,03598406 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,02699909 0,03596444 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,02699909 0,03594484 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,02699909 0,03592526 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,02699909 0,0359057 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,02699909 0,03588617 ! iron ion transport GO:0006826 65 27 0,000 0,02699909 0,03586666 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,02699909 0,03584716 ! superoxide metabolic process GO:0006801 41 27 0,000 0,02699909 0,03582769 ! tube lumen formation GO:0035148 59 27 0,000 0,02699909 0,03580824 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,02699909 0,03578881 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,02699909 0,0357694 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,02699909 0,03575002 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,02699909 0,03573065 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,02699909 0,0357113 ! response to starvation GO:0042594 47 27 0,000 0,02699909 0,03569198 ! response to toxin GO:0009636 49 27 0,000 0,02699909 0,03567268 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,02699909 0,03565339 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,02699909 0,03563413 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,02699909 0,03561489 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,02699909 0,03559567 ! leukocyte proliferation GO:0070661 59 27 0,000 0,02699909 0,03557647 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,02699909 0,03555729 ! neuron fate commitment GO:0048663 52 28 0,000 0,02798532 0,03683629 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,02798532 0,03681645 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,02798532 0,03679663 ! protein amino acid acylation GO:0043543 59 28 0,000 0,02798532 0,03677684 ! vesicle docking GO:0048278 55 28 0,000 0,02798532 0,03675707 ! circadian rhythm GO:0007623 56 28 0,000 0,02798532 0,03673732 ! dendrite development GO:0016358 67 28 0,000 0,02798532 0,03671759 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,02798532 0,03669788 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,02798532 0,03667819 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,02798532 0,03665852 ! base-excision repair GO:0006284 41 28 0,000 0,02798532 0,03663888 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,02798532 0,03661925 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,02798532 0,03659965 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,02798532 0,03658007 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,02798532 0,03656051 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,02798532 0,03654097 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,02798532 0,03652145 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,02798532 0,03650195 ! glutathione metabolic process GO:0006749 42 28 0,000 0,02798532 0,03648247 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,02798532 0,03646301 ! lipid oxidation GO:0034440 48 28 0,000 0,02798532 0,03644357 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,02798532 0,03642416 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,02798532 0,03640476 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,02897058 0,03766639 ! translational initiation GO:0006413 66 29 0,000 0,02897058 0,03764635 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,02897058 0,03762634 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,02897058 0,03760634 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,02897058 0,03758637 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,02897058 0,03756642 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,02897058 0,03754649 ! primary neural tube formation GO:0014020 61 29 0,000 0,02897058 0,03752658 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,02897058 0,0375067 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,02897058 0,03748683 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,02897058 0,03746699 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,02897058 0,03744716 ! somitogenesis GO:0001756 52 29 0,000 0,02897058 0,03742736 ! synaptogenesis GO:0007416 46 29 0,000 0,02897058 0,03740758 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,02897058 0,03738782 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,02897058 0,03736808 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,02897058 0,03734836 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,02995487 0,03859692 ! phenol metabolic process GO:0018958 56 30 0,000 0,02995487 0,03857657 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,02995487 0,03855625 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,02995487 0,03853594 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,02995487 0,03851566 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,02995487 0,0384954 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,02995487 0,03847516 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,02995487 0,03845494 ! acute-phase response GO:0006953 50 30 0,000 0,02995487 0,03843475 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,02995487 0,03841457 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,02995487 0,03839442 ! myofibril assembly GO:0030239 50 30 0,000 0,02995487 0,03837428 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,02995487 0,03835417 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,02995487 0,03833408 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,02995487 0,03831401 ! cell fate determination GO:0001709 64 30 0,000 0,02995487 0,03829396 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,02995487 0,03827393 ! phospholipid transport GO:0015914 65 30 0,000 0,02995487 0,03825393 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,02995487 0,03823394 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,02995487 0,03821397 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,02995487 0,03819403 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,02995487 0,0381741 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,02995487 0,0381542 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,02995487 0,03813432 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,03093819 0,03936563 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,03093819 0,03934514 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,03093819 0,03932467 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,03093819 0,03930422 ! cell junction assembly GO:0034329 85 31 0,000 0,03093819 0,03928379 ! regulation of innate immune response GO:0045088 57 31 0,000 0,03093819 0,03926338 ! ovulation cycle process GO:0022602 55 31 0,000 0,03093819 0,039243 ! peptide transport GO:0015833 60 31 0,000 0,03093819 0,03922263 ! male gonad development GO:0008584 56 31 0,000 0,03093819 0,03920229 ! iron ion homeostasis GO:0055072 60 31 0,000 0,03093819 0,03918196 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,03093819 0,03916166 ! detection of light stimulus GO:0009583 44 31 0,000 0,03093819 0,03914138 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,03093819 0,03912112 ! natural killer cell activation GO:0030101 50 31 0,000 0,03093819 0,03910088 ! ensheathment of neurons GO:0007272 64 31 0,000 0,03093819 0,03908067 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,03093819 0,03906047 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,03093819 0,03904029 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,03093819 0,03902014 ! response to heat GO:0009408 54 31 0,000 0,03093819 0,039 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,03093819 0,03897989 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,03192055 0,04019685 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,03192055 0,04017614 ! collagen metabolic process GO:0032963 49 32 0,000 0,03192055 0,04015545 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,03192055 0,04013479 ! spindle organization GO:0007051 50 32 0,000 0,03192055 0,04011414 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,03192055 0,04009352 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,03192055 0,04007291 ! metanephros development GO:0001656 81 32 0,000 0,03192055 0,04005233 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,03192055 0,04003177 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,03192055 0,04001123 ! muscle cell development GO:0055001 52 32 0,000 0,03192055 0,03999071 ! mesoderm formation GO:0001707 73 32 0,000 0,03192055 0,03997022 ! ovulation cycle GO:0042698 57 32 0,000 0,03192055 0,03994974 ! peripheral nervous system development GO:0007422 68 32 0,000 0,03192055 0,03992928 ! BMP signaling pathway GO:0030509 71 32 0,000 0,03192055 0,03990885 ! hindbrain development GO:0030902 65 32 0,000 0,03192055 0,03988844 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,03192055 0,03986804 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,03192055 0,03984767 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,03192055 0,03982732 ! gene silencing GO:0016458 71 32 0,000 0,03192055 0,03980699 ! regulation of pH GO:0006885 56 33 0,000 0,03290193 0,0410099 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,03290193 0,04098899 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,03290193 0,0409681 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,03290193 0,04094723 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,03290193 0,04092638 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,03290193 0,04090555 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,03290193 0,04088475 ! response to ionizing radiation GO:0010212 74 33 0,000 0,03290193 0,04086396 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,03290193 0,0408432 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,03290193 0,04082245 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,03290193 0,04080173 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,03290193 0,04078103 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,03290193 0,04076035 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,03290193 0,04073969 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,03290193 0,04071905 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,03388234 0,04191117 ! glial cell differentiation GO:0010001 67 34 0,000 0,03388234 0,04188996 ! post-embryonic development GO:0009791 76 34 0,000 0,03388234 0,04186877 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,03388234 0,04184761 ! cholesterol transport GO:0030301 62 34 0,000 0,03388234 0,04182646 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,03388234 0,04180534 ! spliceosome assembly GO:0000245 75 34 0,000 0,03388234 0,04178423 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,03388234 0,04176315 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,03388234 0,04174209 ! formation of primary germ layer GO:0001704 76 34 0,000 0,03388234 0,04172105 ! cell fate specification GO:0001708 56 34 0,000 0,03388234 0,04170003 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,03388234 0,04167904 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,03388234 0,04165806 ! adult locomotory behavior GO:0008344 62 34 0,000 0,03388234 0,04163711 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,03388234 0,04161617 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,03486179 0,04279767 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,03486179 0,04277617 ! negative regulation of secretion GO:0051048 68 35 0,000 0,03486179 0,0427547 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,03486179 0,04273325 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,03486179 0,04271182 ! membrane docking GO:0022406 69 35 0,000 0,03486179 0,04269041 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,03486179 0,04266902 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,03486179 0,04264765 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,03486179 0,04262631 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,03486179 0,04260498 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,03486179 0,04258368 ! ceramide metabolic process GO:0006672 72 35 0,000 0,03486179 0,0425624 ! telencephalon development GO:0021537 81 35 0,000 0,03486179 0,04254114 ! sterol transport GO:0015918 63 35 0,000 0,03486179 0,0425199 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,03486179 0,04249868 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,03486179 0,04247749 ! placenta development GO:0001890 53 35 0,000 0,03486179 0,04245631 ! vesicle localization GO:0051648 70 35 0,000 0,03486179 0,04243516 ! regulation of muscle development GO:0048634 82 36 0,000 0,03584028 0,04360448 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,03584028 0,04358277 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,03584028 0,04356109 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,03584028 0,04353943 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,03584028 0,04351779 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,03584028 0,04349617 ! positive regulation of cell development GO:0010720 85 36 0,000 0,03584028 0,04347458 ! regulation of proteolysis GO:0030162 77 36 0,000 0,03584028 0,043453 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,03584028 0,04343145 ! aerobic respiration GO:0009060 56 36 0,000 0,03584028 0,04340991 ! cytokine production GO:0001816 68 36 0,000 0,03584028 0,0433884 ! embryonic organ development GO:0048568 67 36 0,000 0,03584028 0,04336691 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,03584028 0,04334544 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,0368178 0,04450563 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,0368178 0,04448362 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,0368178 0,04446163 ! sister chromatid segregation GO:0000819 65 37 0,000 0,0368178 0,04443966 ! odontogenesis GO:0042476 74 37 0,000 0,0368178 0,04441772 ! actomyosin structure organization GO:0031032 68 37 0,000 0,0368178 0,04439579 ! tissue remodeling GO:0048771 78 37 0,000 0,0368178 0,04437389 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,0368178 0,04435201 ! female gonad development GO:0008585 71 37 0,000 0,0368178 0,04433015 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,0368178 0,04430831 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,0368178 0,0442865 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,0368178 0,0442647 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,0368178 0,04424293 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,03779435 0,0453941 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,03779435 0,04537179 ! meiosis I GO:0007127 74 38 0,000 0,03779435 0,04534951 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,03779435 0,04532725 ! organic anion transport GO:0015711 82 38 0,000 0,03779435 0,045305 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,03779435 0,04528279 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,03779435 0,04526059 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,03779435 0,04523841 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,03779435 0,04521626 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,03779435 0,04519413 ! regulation of protein stability GO:0031647 77 38 0,000 0,03779435 0,04517202 ! spermatid development GO:0007286 69 38 0,000 0,03779435 0,04514993 ! glycogen metabolic process GO:0005977 63 38 0,000 0,03779435 0,04512786 ! pigment metabolic process GO:0042440 87 38 0,000 0,03779435 0,04510581 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,03779435 0,04508379 ! neural tube formation GO:0001841 79 38 0,000 0,03779435 0,04506179 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,03876994 0,04620243 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,03876994 0,0461799 ! negative regulation of binding GO:0051100 71 39 0,000 0,03876994 0,04615739 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,03876994 0,04613491 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,03876994 0,04611245 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,03876994 0,04609001 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,03876994 0,04606759 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,03876994 0,0460452 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,03876994 0,04602282 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,03876994 0,04600047 ! glucan metabolic process GO:0044042 64 39 0,000 0,03876994 0,04597814 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,03974458 0,04711111 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,03974458 0,04708826 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,03974458 0,04706544 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,03974458 0,04704263 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,03974458 0,04701985 ! mismatch repair GO:0006298 58 40 0,000 0,03974458 0,04699709 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,03974458 0,04697436 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,03974458 0,04695164 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,03974458 0,04692895 ! RNA export from nucleus GO:0006405 61 41 0,000 0,04071825 0,0480554 ! mRNA catabolic process GO:0006402 79 41 0,000 0,04071825 0,04803219 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,04071825 0,04800901 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,04071825 0,04798585 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,04071825 0,04796272 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,04071825 0,0479396 ! gliogenesis GO:0042063 91 41 0,000 0,04071825 0,04791651 ! feeding behavior GO:0007631 69 41 0,000 0,04071825 0,04789344 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,04071825 0,04787039 ! mesenchymal cell development GO:0014031 94 41 0,000 0,04071825 0,04784737 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,04071825 0,04782436 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,04071825 0,04780138 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,04071825 0,04777842 ! spermatid differentiation GO:0048515 73 41 0,000 0,04071825 0,04775548 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,04071825 0,04773257 ! RNA modification GO:0009451 64 41 0,000 0,04071825 0,04770968 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,04169096 0,04882599 ! ear morphogenesis GO:0042471 64 42 0,000 0,04169096 0,04880259 ! organic ether metabolic process GO:0018904 59 42 0,000 0,04169096 0,04877922 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,04169096 0,04875587 ! T cell differentiation GO:0030217 93 42 0,000 0,04169096 0,04873254 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,04169096 0,04870923 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,04169096 0,04868595 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,04169096 0,04866269 ! regulation of protein secretion GO:0050708 77 42 0,000 0,04169096 0,04863945 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,04169096 0,04861623 ! cytokinesis GO:0000910 84 42 0,000 0,04169096 0,04859304 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,04169096 0,04856986 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,04266271 0,04967826 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,04266271 0,0496546 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,04266271 0,04963095 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,04266271 0,04960733 ! regulation of tube size GO:0035150 76 43 0,000 0,04266271 0,04958373 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,04266271 0,04956015 ! glucose transport GO:0015758 66 43 0,000 0,04266271 0,04953659 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,04266271 0,04951306 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,04266271 0,04948955 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,04266271 0,04946606 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,04266271 0,0494426 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,04266271 0,04941915 ! segmentation GO:0035282 78 43 0,000 0,04266271 0,04939573 ! ion transmembrane transport GO:0034220 79 43 0,000 0,04266271 0,04937233 ! neuron migration GO:0001764 85 43 0,000 0,04266271 0,04934896 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,04266271 0,0493256 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,0436335 0,05042415 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,0436335 0,0504003 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,0436335 0,05037649 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,0436335 0,05035269 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,0436335 0,05032892 ! hexose transport GO:0008645 68 44 0,000 0,0436335 0,05030516 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,0436335 0,05028144 ! striated muscle contraction GO:0006941 85 44 0,000 0,0436335 0,05025773 ! phagocytosis GO:0006909 105 44 0,000 0,0436335 0,05023405 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,0436335 0,05021038 ! double-strand break repair GO:0006302 85 44 0,000 0,0436335 0,05018674 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,04460334 0,0512781 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,04460334 0,05125398 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,04460334 0,05122988 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,04460334 0,05120581 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,04460334 0,05118175 ! B cell differentiation GO:0030183 124 45 0,000 0,04460334 0,05115772 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,04460334 0,05113372 ! female gamete generation GO:0007292 71 45 0,000 0,04460334 0,05110973 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,04460334 0,05108577 ! developmental growth GO:0048589 88 45 0,000 0,04460334 0,05106183 ! maintenance of location in cell GO:0051651 101 45 0,000 0,04460334 0,05103792 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,04557222 0,05212216 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,04557222 0,05209777 ! glycolysis GO:0006096 71 46 0,000 0,04557222 0,0520734 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,04557222 0,05204905 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,04557222 0,05202473 ! leukocyte migration GO:0050900 75 46 0,000 0,04557222 0,05200043 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,04557222 0,05197616 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,04557222 0,0519519 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,04557222 0,05192767 ! pigmentation GO:0043473 103 46 0,000 0,04557222 0,05190346 ! cell growth GO:0016049 90 46 0,000 0,04557222 0,05187928 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,04557222 0,05185511 ! neural tube development GO:0021915 91 47 0,000 0,04654014 0,05293183 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,04654014 0,0529072 ! response to insulin stimulus GO:0032868 98 47 0,000 0,04654014 0,05288259 ! positive regulation of defense response GO:0031349 88 48 0,000 0,04750711 0,05395624 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,04750711 0,05393117 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,04750711 0,05390612 ! cellular component disassembly GO:0022411 89 48 0,000 0,04750711 0,05388109 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,04750711 0,05385609 ! endosome transport GO:0016197 127 48 0,000 0,04750711 0,05383111 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,04750711 0,05380616 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,04750711 0,05378122 ! male sex differentiation GO:0046661 93 48 0,000 0,04750711 0,05375631 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,04750711 0,05373143 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,04750711 0,05370656 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,04750711 0,05368172 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,04750711 0,0536569 ! methylation GO:0032259 97 48 0,000 0,04750711 0,05363211 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,04847313 0,05469739 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,04847313 0,05467214 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,04847313 0,05464691 ! JNK cascade GO:0007254 106 49 0,000 0,04847313 0,05462171 ! protein homooligomerization GO:0051260 84 49 0,000 0,04847313 0,05459652 ! regulation of action potential GO:0001508 102 50 0,000 0,0494382 0,05565784 ! regulation of ion transport GO:0043269 86 50 0,000 0,0494382 0,0556322 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,0494382 0,05560659 ! endocrine system development GO:0035270 109 50 0,000 0,0494382 0,055581 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,0494382 0,05555543 ! activation of caspase activity GO:0006919 95 50 0,000 0,0494382 0,05552989 ! regulation of ossification GO:0030278 123 50 0,000 0,0494382 0,05550437 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,0494382 0,05547888 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,0494382 0,0554534 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,0494382 0,05542795 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,0494382 0,05540253 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,05040231 0,05645706 ! viral infectious cycle GO:0019058 104 51 0,000 0,05040231 0,05643118 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,05040231 0,05640533 ! peptide metabolic process GO:0006518 80 51 0,000 0,05040231 0,0563795 ! response to temperature stimulus GO:0009266 84 51 0,000 0,05040231 0,0563537 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,05040231 0,05632792 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,05040231 0,05630217 ! positive regulation of binding GO:0051099 88 52 0,000 0,05136547 0,05735185 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,05136547 0,05732565 ! Notch signaling pathway GO:0007219 111 52 0,000 0,05136547 0,05729947 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,05136547 0,05727332 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,05136547 0,05724719 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,05136547 0,05722109 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,05136547 0,05719501 ! excretion GO:0007588 87 52 0,000 0,05136547 0,05716895 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,05136547 0,05714292 ! histone modification GO:0016570 104 52 0,000 0,05136547 0,05711691 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,05136547 0,05709092 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,05136547 0,05706496 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,05136547 0,05703902 ! amino acid activation GO:0043038 98 52 0,000 0,05136547 0,05701311 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,05232768 0,05805474 ! positive regulation of growth GO:0045927 96 53 0,000 0,05232768 0,05802838 ! inner ear development GO:0048839 89 53 0,000 0,05232768 0,05800205 ! chromatin remodeling GO:0006338 122 53 0,000 0,05232768 0,05797575 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,05232768 0,05794947 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,05232768 0,05792321 ! cartilage development GO:0051216 99 53 0,000 0,05232768 0,05789698 ! synapse organization GO:0050808 102 53 0,000 0,05232768 0,05787077 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,05328895 0,05890719 ! regulation of translational initiation GO:0006446 87 54 0,000 0,05328895 0,05888055 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,05328895 0,05885393 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,05328895 0,05882734 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,05328895 0,05880077 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,05328895 0,05877422 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,05328895 0,0587477 ! membrane fusion GO:0006944 122 54 0,000 0,05328895 0,0587212 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,05328895 0,05869472 ! covalent chromatin modification GO:0016569 115 54 0,000 0,05328895 0,05866827 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,05328895 0,05864184 ! regulation of cell shape GO:0008360 142 54 0,000 0,05328895 0,05861544 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,05328895 0,05858906 ! RNA catabolic process GO:0006401 103 55 0,000 0,05424926 0,05961806 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,05424926 0,05959125 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,05424926 0,05956447 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,05424926 0,05953771 ! cell recognition GO:0008037 98 55 0,000 0,05424926 0,05951098 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,05424926 0,05948427 ! cell maturation GO:0048469 107 55 0,000 0,05424926 0,05945758 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,05424926 0,05943092 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,05424926 0,05940428 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,05520863 0,06042773 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,05520863 0,06040066 ! glucose catabolic process GO:0006007 88 56 0,000 0,05520863 0,06037363 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,05520863 0,06034661 ! regulation of DNA replication GO:0006275 105 56 0,000 0,05520863 0,06031963 ! RNA elongation GO:0006354 90 56 0,000 0,05520863 0,06029266 ! chloride transport GO:0006821 102 57 0,000 0,05616705 0,06131193 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,05616705 0,06128455 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,05616705 0,06125719 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,05616705 0,06122986 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,05616705 0,06120255 ! heart morphogenesis GO:0003007 105 57 0,000 0,05616705 0,06117526 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,05616705 0,061148 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,05616705 0,06112076 ! regulation of actin filament length GO:0030832 118 58 0,000 0,05712453 0,06213501 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,05712453 0,06210735 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,05712453 0,06207973 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,05712453 0,06205212 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,05712453 0,06202454 ! gastrulation GO:0007369 122 58 0,000 0,05712453 0,06199699 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,05712453 0,06196946 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,05712453 0,06194196 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,05712453 0,06191447 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,05712453 0,06188702 ! maintenance of location GO:0051235 124 58 0,000 0,05712453 0,06185959 ! nuclear export GO:0051168 110 59 0,000 0,05808106 0,06286754 ! establishment of organelle localization GO:0051656 122 59 0,000 0,05808106 0,0628397 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,05903665 0,0638453 ! lipid modification GO:0030258 112 60 0,000 0,05903665 0,06381705 ! DNA catabolic process GO:0006308 94 60 0,000 0,05903665 0,06378883 ! regulation of endocytosis GO:0030100 104 60 0,000 0,05903665 0,06376063 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,05903665 0,06373245 ! adult behavior GO:0030534 104 60 0,000 0,05903665 0,0637043 ! kidney development GO:0001822 133 60 0,000 0,05903665 0,06367618 ! positive regulation of secretion GO:0051047 110 61 0,000 0,0599913 0,06467729 ! regulation of cellular component size GO:0032535 125 61 0,000 0,0599913 0,06464876 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,0599913 0,06462026 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,0599913 0,06459178 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,0599913 0,06456332 ! regulation of heart contraction GO:0008016 123 61 0,000 0,0599913 0,06453489 ! camera-type eye development GO:0043010 126 61 0,000 0,0599913 0,06450649 ! proton transport GO:0015992 117 61 0,000 0,0599913 0,06447811 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,0599913 0,06444975 ! viral reproductive process GO:0022415 132 62 0,000 0,060945 0,06544556 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,060945 0,0654168 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,060945 0,06538807 ! tRNA processing GO:0008033 102 62 0,000 0,060945 0,06535937 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,060945 0,06533069 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,06189777 0,06632291 ! regulation of mitosis GO:0007088 112 63 0,000 0,06189777 0,06629384 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,06189777 0,06626479 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,06189777 0,06623576 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,06189777 0,06620676 ! hydrogen transport GO:0006818 121 64 0,000 0,06284959 0,06719543 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,06284959 0,06716603 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,06284959 0,06713666 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,06284959 0,06710732 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,06284959 0,067078 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,06380048 0,06806313 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,06380048 0,06803342 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,06380048 0,06800374 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,06380048 0,06797408 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,06380048 0,06794445 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,06380048 0,06791484 ! ear development GO:0043583 114 66 0,000 0,06475042 0,06889603 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,06475042 0,06886604 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,06475042 0,06883607 ! gonad development GO:0008406 115 66 0,000 0,06475042 0,06880613 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,06475042 0,06877621 ! activation of MAPK activity GO:0000187 124 67 0,000 0,06569943 0,0697539 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,06569943 0,0697236 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,06569943 0,06969332 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,06569943 0,06966307 ! secondary metabolic process GO:0019748 125 67 0,000 0,06569943 0,06963285 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,06569943 0,06960265 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,06664751 0,07057645 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,06664751 0,07054587 ! hexose catabolic process GO:0019320 113 68 0,000 0,06664751 0,07051532 ! extracellular matrix organization GO:0030198 146 68 0,000 0,06664751 0,07048479 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,06664751 0,07045429 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,06664751 0,07042382 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,06664751 0,07039337 ! viral reproduction GO:0016032 142 68 0,000 0,06664751 0,07036295 ! regulation of lipase activity GO:0060191 137 68 0,000 0,06664751 0,07033255 ! adaptive immune response GO:0002250 126 68 0,000 0,06664751 0,07030219 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,06664751 0,07027184 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,06759465 0,07123974 ! lung development GO:0030324 165 69 0,000 0,06759465 0,07120902 ! urogenital system development GO:0001655 149 69 0,000 0,06759465 0,07117833 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,06759465 0,07114766 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,06759465 0,07111702 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,06759465 0,07108641 ! developmental maturation GO:0021700 128 69 0,000 0,06759465 0,07105582 ! single fertilization GO:0007338 83 69 0,000 0,06759465 0,07102526 ! cell redox homeostasis GO:0045454 114 70 0,000 0,06854085 0,07198852 ! germ cell development GO:0007281 133 70 0,000 0,06854085 0,07195758 ! activation of immune response GO:0002253 120 70 0,000 0,06854085 0,07192668 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,06854085 0,07189579 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,06948612 0,07285605 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,06948612 0,07282479 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,06948612 0,07279357 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,06948612 0,07276236 ! appendage morphogenesis GO:0035107 150 72 0,000 0,07043046 0,07371963 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,07043046 0,07368806 ! respiratory tube development GO:0030323 171 72 0,000 0,07043046 0,07365651 ! B cell activation GO:0042113 179 72 0,000 0,07043046 0,073625 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,07043046 0,0735935 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,07043046 0,07356204 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,07043046 0,0735306 ! appendage development GO:0048736 151 73 0,000 0,07137387 0,07448371 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,07137387 0,0744519 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,07137387 0,07442013 ! regulation of immune effector process GO:0002697 156 73 0,000 0,07137387 0,07438838 ! acute inflammatory response GO:0002526 118 74 0,000 0,07231634 0,07533852 ! amino acid transport GO:0006865 148 74 0,000 0,07231634 0,0753064 ! regulation of caspase activity GO:0043281 136 74 0,000 0,07231634 0,07527432 ! respiratory system development GO:0060541 175 74 0,000 0,07231634 0,07524226 ! organelle localization GO:0051640 155 74 0,000 0,07231634 0,07521023 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,07325789 0,07615703 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,07325789 0,07612464 ! reproductive structure development GO:0048608 131 75 0,000 0,07325789 0,07609227 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,07325789 0,07605993 ! axon guidance GO:0007411 162 75 0,000 0,07325789 0,07602762 ! rhythmic process GO:0048511 142 75 0,000 0,07325789 0,07599534 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,0741985 0,07693843 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,0741985 0,07690579 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,0741985 0,07687317 ! regulation of blood pressure GO:0008217 134 76 0,000 0,0741985 0,07684059 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,0741985 0,07680803 ! amine catabolic process GO:0009310 136 77 0,000 0,07513819 0,07774782 ! neurotransmitter transport GO:0006836 142 77 0,000 0,07513819 0,0777149 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,07513819 0,07768201 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,07513819 0,07764915 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,07513819 0,07761632 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,07513819 0,07758352 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,07513819 0,07755074 ! regulation of catabolic process GO:0009894 173 77 0,000 0,07513819 0,07751799 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,07607695 0,07845335 ! antigen processing and presentation GO:0019882 117 78 0,000 0,07607695 0,07842025 ! fertilization GO:0009566 99 78 0,000 0,07607695 0,07838718 ! blood coagulation GO:0007596 151 79 0,000 0,07701479 0,07932003 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,07701479 0,07928661 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,07701479 0,07925321 ! protein oligomerization GO:0051259 149 79 0,000 0,07701479 0,07921984 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,07795169 0,08014983 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,07795169 0,08011611 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,07795169 0,08008242 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,07795169 0,08004876 ! meiosis GO:0007126 143 81 0,000 0,07888768 0,08097588 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 0,000 0,07888768 0,08094187 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,07888768 0,08090789 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,07982274 0,08183254 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,07982274 0,08179822 ! protein import into nucleus GO:0006606 174 82 0,000 0,07982274 0,08176392 ! meiotic cell cycle GO:0051321 144 82 0,000 0,07982274 0,08172965 ! exocytosis GO:0006887 153 83 0,000 0,08075688 0,08265147 ! response to drug GO:0042493 149 83 0,000 0,08075688 0,08261685 ! response to oxygen levels GO:0070482 183 83 0,000 0,08075688 0,08258227 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,08075688 0,08254772 ! nuclear import GO:0051170 177 83 0,000 0,08075688 0,08251319 ! inorganic anion transport GO:0015698 156 83 0,000 0,08075688 0,0824787 ! T cell activation GO:0042110 189 84 0,000 0,08169009 0,08339695 ! response to nutrient GO:0007584 135 84 0,000 0,08169009 0,08336211 ! digestion GO:0007586 130 84 0,000 0,08169009 0,0833273 ! hemostasis GO:0007599 165 85 0,000 0,08262239 0,08424311 ! negative regulation of transport GO:0051051 164 85 0,000 0,08262239 0,08420796 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,08262239 0,08417285 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,08262239 0,08413776 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,08262239 0,0841027 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,08448421 0,08596207 ! nucleosome assembly GO:0006334 126 87 0,000 0,08448421 0,08592629 ! regulation of protein transport GO:0051223 165 87 0,000 0,08448421 0,08589053 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,08541375 0,08679942 ! amine biosynthetic process GO:0009309 146 88 0,000 0,08541375 0,08676332 ! sensory perception of smell GO:0007608 117 88 0,000 0,08541375 0,08672726 ! chromatin assembly GO:0031497 128 88 0,000 0,08541375 0,08669123 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,08541375 0,08665523 ! regulation of DNA binding GO:0051101 167 89 0,000 0,08634237 0,08756098 ! tube morphogenesis GO:0035239 194 89 0,000 0,08634237 0,08752465 ! cellular defense response GO:0006968 123 89 0,000 0,08634237 0,08748835 ! protein localization in nucleus GO:0034504 192 89 0,000 0,08634237 0,08745208 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,08727007 0,08835507 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,08727007 0,08831847 ! gland development GO:0048732 220 91 0,000 0,08819686 0,08921943 ! defense response to bacterium GO:0042742 112 91 0,000 0,08819686 0,0891825 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,08912273 0,09008143 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,08912273 0,09004418 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,09004769 0,09094109 ! amine transport GO:0015837 181 93 0,000 0,09004769 0,09090351 ! vitamin metabolic process GO:0006766 153 93 0,000 0,09004769 0,09086596 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,09097173 0,0917605 ! female pregnancy GO:0007565 166 94 0,000 0,09097173 0,09172263 ! sterol metabolic process GO:0016125 166 94 0,000 0,09097173 0,09168479 ! regulation of membrane potential GO:0042391 179 94 0,000 0,09097173 0,09164698 ! regulation of defense response GO:0031347 171 95 0,000 0,09189486 0,09253881 ! nucleosome organization GO:0034728 143 95 0,000 0,09189486 0,09250068 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,09189486 0,09246258 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,09189486 0,09242452 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,09189486 0,09238648 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,09189486 0,09234848 ! sex differentiation GO:0007548 171 96 0,000 0,09281708 0,0932369 ! regulation of T cell activation GO:0050863 175 96 0,000 0,09281708 0,09319857 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,09373839 0,094085 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,09373839 0,09404636 ! transcription initiation GO:0006352 171 97 0,000 0,09373839 0,09400776 ! regulation of protein localization GO:0032880 188 97 0,000 0,09373839 0,09396918 ! leukocyte differentiation GO:0002521 232 98 0,000 0,09465879 0,09485292 ! forebrain development GO:0030900 210 98 0,000 0,09465879 0,09481403 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,09649687 0,09661551 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,09649687 0,09657593 ! positive regulation of immune response GO:0050778 175 100 0,000 0,09649687 0,09653638 ! hormone metabolic process GO:0042445 171 100 0,000 0,09649687 0,09649687