pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/7112-8-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of translation GO:0017148 12 12 2,000 4,833E-07 8,907E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 1,413E-05 0,01301779 ! regulation of mitosis GO:0007088 37 36 2,000 1,54E-05 9,46E-03 GO:0051783|regulation of nuclear division, ! positive regulation of cell growth GO:0030307 6 6 1,000 2,844E-05 0,01310201 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 2,844E-05 0,0104816 ! regulation of Rho GTPase activity GO:0032319 6 6 1,000 2,844E-05 8,735E-03 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 2,844E-05 7,487E-03 ! regulation of cell cycle process GO:0010564 50 48 2,000 3,696E-05 8,515E-03 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 3,978E-05 8,146E-03 ! keratinocyte proliferation GO:0043616 7 7 1,000 3,978E-05 7,331E-03 ! regulation of stress fiber formation GO:0051492 9 8 1,000 5,3E-05 8,88E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 5,3E-05 8,14E-03 ! positive regulation of cell size GO:0045793 9 9 1,000 6,809E-05 9,653E-03 ! negative regulation of caspase activity GO:0043154 9 9 1,000 6,809E-05 8,963E-03 ! regulation of dephosphorylation GO:0035303 9 9 1,000 6,809E-05 8,366E-03 ! regulation of actin filament bundle formation GO:0032231 10 9 1,000 6,809E-05 7,843E-03 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 2,000 7,246E-05 7,855E-03 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 8,504E-05 8,708E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 8,504E-05 8,249E-03 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 9,645E-05 8,888E-03 ! skin development GO:0043588 11 11 1,000 1,039E-04 9,115E-03 ! regulation of translation GO:0006417 69 69 2,000 1,102E-04 9,23E-03 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 1,102E-04 8,829E-03 ! negative regulation of signal transduction GO:0009968 71 71 2,000 1,2E-04 9,216E-03 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 1,245E-04 9,181E-03 ! negative regulation of cell communication GO:0010648 76 76 2,000 1,47E-04 0,01042305 ! negative regulation of protein modification process GO:0031400 13 13 1,000 1,471E-04 0,01003873 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 1,471E-04 9,68E-03 GO:0001952|regulation of cell-matrix adhesion, ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 2,556E-04 0,0162458 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 2,556E-04 0,01570428 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 2,874E-04 0,01708414 ! regulation of cell growth GO:0001558 97 96 2,000 2,943E-04 0,01694983 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 3,128E-04 0,0174695 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 3,935E-04 0,0213301 ! RNA export from nucleus GO:0006405 22 22 1,000 4,325E-04 0,02277506 ! positive regulation of growth GO:0045927 23 23 1,000 4,733E-04 0,02423241 ! negative regulation of cell migration GO:0030336 26 26 1,000 6,066E-04 0,03021686 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 6,066E-04 0,02942167 ! response to insulin stimulus GO:0032868 28 26 1,000 6,066E-04 0,02866727 ! keratinocyte differentiation GO:0030216 28 28 1,000 7,045E-04 0,03245828 ! epidermal cell differentiation GO:0009913 31 31 1,000 8,646E-04 0,03886438 ! negative regulation of cell motion GO:0051271 31 31 1,000 8,646E-04 0,03793904 ! nuclear export GO:0051168 32 32 1,000 9,215E-04 0,03949652 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 1,041E-03 0,04358949 ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 1,233E-03 0,05048034 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 1,233E-03 0,04938295 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 1,233E-03 0,04833224 ! negative regulation of kinase activity GO:0033673 38 38 1,000 1,3E-03 0,04991576 ! negative regulation of transferase activity GO:0051348 40 40 1,000 1,44E-03 0,05416865 ! regulation of caspase activity GO:0043281 41 41 1,000 1,513E-03 0,05576431 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 1,513E-03 0,05467089 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 1,587E-03 0,05625683 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 1,587E-03 0,05519538 ! mitochondrion organization GO:0007005 44 43 1,000 1,663E-03 0,05677176 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 1,741E-03 0,05834851 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 1,821E-03 0,05992547 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 1,821E-03 0,05887415 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 1,821E-03 0,05785908 ! regulation of actin filament-based process GO:0032970 47 46 1,000 1,902E-03 0,05941767 ! regulation of peptidase activity GO:0052547 46 46 1,000 1,902E-03 0,05842737 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 1,902E-03 0,05746955 ! positive regulation of ligase activity GO:0051351 47 46 1,000 1,902E-03 0,05654262 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 2,07E-03 0,06055105 ! ossification GO:0001503 50 49 1,000 2,156E-03 0,06209311 GO:0060348|bone development, ! regulation of ligase activity GO:0051340 50 49 1,000 2,156E-03 0,06113783 ! RNA transport GO:0050658 50 50 1,000 2,244E-03 0,06267165 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! RNA localization GO:0006403 52 52 1,000 2,426E-03 0,0667227 ! regulation of GTPase activity GO:0043087 53 52 1,000 2,426E-03 0,06574148 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 2,519E-03 0,0672772 ! regulation of cell adhesion GO:0030155 56 55 1,000 2,71E-03 0,07135461 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 3,324E-03 0,08629066 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 3,432E-03 0,08786036 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 3,654E-03 0,09224172 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 3,767E-03 0,0938111 ! regulation of cell size GO:0008361 68 68 1,000 4,116E-03 0,10113552 ! regulation of cell migration GO:0030334 71 71 1,000 4,479E-03 0,10862071 ! ribosome biogenesis GO:0042254 71 71 1,000 4,479E-03 0,10721005 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 4,604E-03 0,10877497 ! regulation of protein modification process GO:0031399 79 78 1,000 5,384E-03 0,12559376 ! regulation of locomotion GO:0040012 79 79 1,000 5,519E-03 0,12714649 ! nuclear transport GO:0051169 79 79 1,000 5,519E-03 0,12557678 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 1,000 5,519E-03 0,12404535 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 7,113E-03 0,15794946 ! rRNA transcription GO:0009303 5 5 0,000 7,248E-03 0,15903439 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 7,248E-03 0,1571634 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 7,248E-03 0,15533592 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 7,248E-03 0,15355045 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 7,248E-03 0,15180555 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 7,248E-03 0,15009987 ! reproductive cellular process GO:0048610 5 5 0,000 7,248E-03 0,1484321 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 7,248E-03 0,14680098 ! negative regulation of blood pressure GO:0045776 6 5 0,000 7,248E-03 0,14520531 ! prostate gland development GO:0030850 5 5 0,000 7,248E-03 0,14364397 ! metencephalon development GO:0022037 5 5 0,000 7,248E-03 0,14211584 ! water transport GO:0006833 5 5 0,000 7,248E-03 0,14061988 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 7,248E-03 0,13915509 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 7,248E-03 0,1377205 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 7,248E-03 0,13631519 ! glycerol metabolic process GO:0006071 5 5 0,000 7,248E-03 0,13493827 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 7,248E-03 0,13358889 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 7,248E-03 0,13226623 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 7,248E-03 0,1309695 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 7,248E-03 0,12969795 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 7,248E-03 0,12845085 ! filopodium assembly GO:0046847 7 5 0,000 7,248E-03 0,12722751 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 7,248E-03 0,12602725 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 7,248E-03 0,12484943 ! GTP metabolic process GO:0046039 5 5 0,000 7,248E-03 0,12369342 ! establishment of tissue polarity GO:0007164 5 5 0,000 7,248E-03 0,12255861 ! mRNA stabilization GO:0048255 5 5 0,000 7,248E-03 0,12144444 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 7,248E-03 0,12035035 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 7,248E-03 0,11927579 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 7,248E-03 0,11822026 ! social behavior GO:0035176 5 5 0,000 7,248E-03 0,11718324 ! macrophage chemotaxis GO:0048246 6 5 0,000 7,248E-03 0,11616425 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 7,248E-03 0,11516283 ! memory GO:0007613 5 5 0,000 7,248E-03 0,11417854 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 7,248E-03 0,11321092 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 7,248E-03 0,11225957 ! membrane hyperpolarization GO:0060081 5 5 0,000 7,248E-03 0,11132407 ! response to lipid GO:0033993 5 5 0,000 7,248E-03 0,11040404 ! erythrocyte maturation GO:0043249 5 5 0,000 7,248E-03 0,10949909 ! hippocampus development GO:0021766 6 5 0,000 7,248E-03 0,10860885 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 7,248E-03 0,10773297 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 7,248E-03 0,10687111 ! middle ear morphogenesis GO:0042474 5 5 0,000 7,248E-03 0,10602293 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 7,248E-03 0,1051881 ! mechanosensory behavior GO:0007638 5 5 0,000 7,248E-03 0,10436632 ! heart looping GO:0001947 5 5 0,000 7,248E-03 0,10355728 ! negative regulation of endocytosis GO:0045806 5 5 0,000 7,248E-03 0,10276068 ! response to interferon-gamma GO:0034341 5 5 0,000 7,248E-03 0,10197625 ! pseudouridine synthesis GO:0001522 5 5 0,000 7,248E-03 0,1012037 ! endocrine pancreas development GO:0031018 5 5 0,000 7,248E-03 0,10044277 ! pH reduction GO:0045851 5 5 0,000 7,248E-03 0,0996932 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 7,248E-03 0,09895473 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 7,248E-03 0,09822712 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 7,248E-03 0,09751014 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 7,248E-03 0,09680354 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 7,248E-03 0,09610711 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 7,248E-03 0,09542063 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 7,248E-03 0,09474389 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 7,248E-03 0,09407668 ! adrenal gland development GO:0030325 5 5 0,000 7,248E-03 0,0934188 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 7,248E-03 0,09277006 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 7,248E-03 0,09213027 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 7,248E-03 0,09149924 ! astrocyte differentiation GO:0048708 5 5 0,000 7,248E-03 0,09087679 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 7,248E-03 0,09026276 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 7,248E-03 0,08965697 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 7,248E-03 0,08905926 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 7,248E-03 0,08846946 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 7,248E-03 0,08788743 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 7,248E-03 0,087313 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 7,248E-03 0,08674603 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 7,248E-03 0,08618638 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 7,248E-03 0,0856339 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 7,248E-03 0,08508846 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 7,248E-03 0,08454993 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 7,248E-03 0,08401817 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 7,248E-03 0,08349306 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 7,248E-03 0,08297446 ! response to ATP GO:0033198 5 5 0,000 7,248E-03 0,08246228 ! regulation of type I interferon production GO:0032479 5 5 0,000 7,248E-03 0,08195637 ! regulation of appetite GO:0032098 5 5 0,000 7,248E-03 0,08145664 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 7,248E-03 0,08096296 ! paraxial mesoderm development GO:0048339 5 5 0,000 7,248E-03 0,08047523 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 7,248E-03 0,07999335 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 7,248E-03 0,0795172 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 7,248E-03 0,07904668 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 7,248E-03 0,0785817 ! receptor clustering GO:0043113 5 5 0,000 7,248E-03 0,07812216 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 7,248E-03 0,07766796 ! fear response GO:0042596 5 5 0,000 7,248E-03 0,07721901 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 7,248E-03 0,07677522 ! lens development in camera-type eye GO:0002088 5 5 0,000 7,248E-03 0,07633651 ! retinol metabolic process GO:0042572 5 5 0,000 7,248E-03 0,07590278 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 7,248E-03 0,07547395 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 7,248E-03 0,07504994 ! positive regulation of exocytosis GO:0045921 6 5 0,000 7,248E-03 0,07463066 ! parturition GO:0007567 5 5 0,000 7,248E-03 0,07421605 ! cellular glucose homeostasis GO:0001678 5 5 0,000 7,248E-03 0,07380602 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 7,248E-03 0,07340049 ! Schwann cell differentiation GO:0014037 5 5 0,000 7,248E-03 0,07299939 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 7,248E-03 0,07260266 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 7,248E-03 0,07221021 ! protein heterooligomerization GO:0051291 5 5 0,000 7,248E-03 0,07182198 ! regulation of gliogenesis GO:0014013 5 5 0,000 7,248E-03 0,07143791 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 7,248E-03 0,07105792 ! response to UV-B GO:0010224 5 5 0,000 7,248E-03 0,07068195 ! oligodendrocyte development GO:0014003 5 5 0,000 7,248E-03 0,07030994 ! hyaluronan metabolic process GO:0030212 5 5 0,000 7,248E-03 0,06994183 ! activated T cell proliferation GO:0050798 5 5 0,000 7,248E-03 0,06957755 ! interaction with symbiont GO:0051702 5 5 0,000 7,248E-03 0,06921704 ! cellular extravasation GO:0045123 5 5 0,000 7,248E-03 0,06886025 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 7,248E-03 0,06850712 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 7,248E-03 0,0681576 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 7,248E-03 0,06781162 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 7,248E-03 0,06746914 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 7,248E-03 0,06713009 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 7,248E-03 0,06679444 ! response to amine stimulus GO:0014075 5 5 0,000 7,248E-03 0,06646213 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 7,248E-03 0,06613311 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 7,248E-03 0,06580733 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 7,248E-03 0,06548475 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 7,248E-03 0,06516531 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 7,248E-03 0,06484897 ! neuron recognition GO:0008038 5 5 0,000 7,248E-03 0,06453569 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 7,248E-03 0,06422543 ! decidualization GO:0046697 5 5 0,000 7,248E-03 0,06391813 ! hair follicle maturation GO:0048820 5 5 0,000 7,248E-03 0,06361376 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 7,248E-03 0,06331227 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 7,248E-03 0,06301363 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 7,248E-03 0,06271779 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 7,248E-03 0,06242471 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 7,248E-03 0,06213437 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 7,248E-03 0,06184671 ! postreplication repair GO:0006301 5 5 0,000 7,248E-03 0,0615617 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 7,248E-03 0,06127931 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 7,248E-03 0,06099949 ! histone methylation GO:0016571 5 5 0,000 7,248E-03 0,06072222 ! DNA methylation GO:0006306 5 5 0,000 7,248E-03 0,06044746 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 7,248E-03 0,06017517 ! T cell lineage commitment GO:0002360 5 5 0,000 7,248E-03 0,05990533 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 7,248E-03 0,0596379 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 7,248E-03 0,05937284 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 7,248E-03 0,05911013 ! intracellular cholesterol transport GO:0032367 5 5 0,000 7,248E-03 0,05884973 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 7,248E-03 0,05859162 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 7,248E-03 0,05833576 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 7,248E-03 0,05808213 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 7,248E-03 0,05783069 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 7,248E-03 0,05758142 ! sterol catabolic process GO:0016127 5 5 0,000 7,248E-03 0,05733429 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 7,248E-03 0,05708927 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 7,248E-03 0,05684634 ! detection of biotic stimulus GO:0009595 5 5 0,000 7,248E-03 0,05660546 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 7,248E-03 0,05636662 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 7,248E-03 0,05612979 ! zymogen activation GO:0031638 5 5 0,000 7,248E-03 0,05589493 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 7,248E-03 0,05566204 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 7,248E-03 0,05543107 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 7,248E-03 0,05520202 ! peptidyl-lysine modification GO:0018205 5 5 0,000 7,248E-03 0,05497485 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 7,248E-03 0,05474954 ! peptidyl-histidine modification GO:0018202 5 5 0,000 7,248E-03 0,05452608 ! nucleosome positioning GO:0016584 5 5 0,000 7,248E-03 0,05430443 ! regulation of isotype switching GO:0045191 5 5 0,000 7,248E-03 0,05408457 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 7,248E-03 0,05386649 ! negative regulation of neurological system process GO:0031645 5 5 0,000 7,248E-03 0,05365016 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 7,248E-03 0,05343556 ! glutathione biosynthetic process GO:0006750 5 5 0,000 7,248E-03 0,05322266 ! NADPH regeneration GO:0006740 5 5 0,000 7,248E-03 0,05301146 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 7,248E-03 0,05280193 ! positive regulation of epidermis development GO:0045684 5 5 0,000 7,248E-03 0,05259405 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 7,248E-03 0,0523878 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 7,248E-03 0,05218316 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 7,248E-03 0,05198011 ! sarcomere organization GO:0045214 5 5 0,000 7,248E-03 0,05177864 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 7,248E-03 0,05157872 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 7,248E-03 0,05138034 ! negative regulation of glucose transport GO:0010829 5 5 0,000 7,248E-03 0,05118348 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 7,248E-03 0,05098813 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 7,248E-03 0,05079425 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 7,248E-03 0,05060185 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 7,248E-03 0,0504109 ! spleen development GO:0048536 5 5 0,000 7,248E-03 0,05022139 ! male genitalia development GO:0030539 5 5 0,000 7,248E-03 0,05003329 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 7,248E-03 0,0498466 ! quaternary ammonium group transport GO:0015697 5 5 0,000 7,248E-03 0,0496613 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 7,248E-03 0,04947737 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 7,248E-03 0,04929479 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 7,248E-03 0,04911356 ! removal of superoxide radicals GO:0019430 6 5 0,000 7,248E-03 0,04893366 ! myeloid cell homeostasis GO:0002262 5 5 0,000 7,248E-03 0,04875507 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 7,248E-03 0,04857778 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 7,248E-03 0,04840177 ! ATP catabolic process GO:0006200 5 5 0,000 7,248E-03 0,04822704 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 7,248E-03 0,04805356 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 7,248E-03 0,04788132 ! blastocyst formation GO:0001825 5 5 0,000 7,248E-03 0,04771032 ! regulation of fibrinolysis GO:0051917 5 5 0,000 7,248E-03 0,04754053 ! embryonic gut development GO:0048566 5 5 0,000 7,248E-03 0,04737195 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 7,248E-03 0,04720455 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 7,248E-03 0,04703834 ! activation of innate immune response GO:0002218 5 5 0,000 7,248E-03 0,04687329 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 7,248E-03 0,0467094 ! catecholamine transport GO:0051937 5 5 0,000 7,248E-03 0,04654665 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 7,248E-03 0,04638503 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 7,248E-03 0,04622453 ! muscle adaptation GO:0043500 5 5 0,000 7,248E-03 0,04606513 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 7,248E-03 0,04590683 ! embryonic heart tube development GO:0035050 5 5 0,000 7,248E-03 0,04574962 ! cardiac cell differentiation GO:0035051 6 5 0,000 7,248E-03 0,04559348 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 7,248E-03 0,0454384 ! defense response to fungus GO:0050832 5 5 0,000 7,248E-03 0,04528437 ! lysogeny GO:0030069 5 5 0,000 7,248E-03 0,04513138 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 7,248E-03 0,04497942 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 7,248E-03 0,04482849 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 7,248E-03 0,04467856 ! response to nicotine GO:0035094 5 5 0,000 7,248E-03 0,04452963 ! establishment of cell polarity GO:0030010 5 5 0,000 7,248E-03 0,04438169 ! mitochondrion localization GO:0051646 5 5 0,000 7,248E-03 0,04423473 ! nucleus localization GO:0051647 5 5 0,000 7,248E-03 0,04408874 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 7,248E-03 0,04394371 ! negative regulation of cell cycle GO:0045786 92 91 1,000 7,268E-03 0,04391477 ! epidermis development GO:0008544 94 94 1,000 7,739E-03 0,0466127 ! anti-apoptosis GO:0006916 100 99 1,000 8,556E-03 0,05136316 ! ectoderm development GO:0007398 99 99 1,000 8,556E-03 0,0511964 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 8,692E-03 0,05184526 ! axon extension GO:0048675 7 6 0,000 8,692E-03 0,05167802 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 8,692E-03 0,05151185 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 8,692E-03 0,05134675 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 8,692E-03 0,0511827 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 8,692E-03 0,0510197 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 8,692E-03 0,05085773 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 8,692E-03 0,05069679 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 8,692E-03 0,05053686 ! virus-host interaction GO:0019048 6 6 0,000 8,692E-03 0,05037794 ! regulation of S phase GO:0033261 6 6 0,000 8,692E-03 0,05022002 ! myotube differentiation GO:0014902 6 6 0,000 8,692E-03 0,05006308 ! regulation of B cell proliferation GO:0030888 6 6 0,000 8,692E-03 0,04990712 ! bone remodeling GO:0046849 6 6 0,000 8,692E-03 0,04975213 ! N-glycan processing GO:0006491 6 6 0,000 8,692E-03 0,0495981 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 8,692E-03 0,04944502 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 8,692E-03 0,04929288 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 8,692E-03 0,04914167 ! retina development in camera-type eye GO:0060041 6 6 0,000 8,692E-03 0,04899139 ! RNA methylation GO:0001510 6 6 0,000 8,692E-03 0,04884203 ! cartilage condensation GO:0001502 7 6 0,000 8,692E-03 0,04869357 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 8,692E-03 0,04854602 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 8,692E-03 0,04839935 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 8,692E-03 0,04825357 ! artery development GO:0060840 6 6 0,000 8,692E-03 0,04810866 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 8,692E-03 0,04796463 ! bile acid metabolic process GO:0008206 6 6 0,000 8,692E-03 0,04782145 ! androgen metabolic process GO:0008209 6 6 0,000 8,692E-03 0,04767912 ! estrogen metabolic process GO:0008210 6 6 0,000 8,692E-03 0,04753764 ! limbic system development GO:0021761 7 6 0,000 8,692E-03 0,047397 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 8,692E-03 0,04725718 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 8,692E-03 0,04711819 ! positive regulation of heart contraction GO:0045823 6 6 0,000 8,692E-03 0,04698001 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 8,692E-03 0,04684265 ! pathogenesis GO:0009405 6 6 0,000 8,692E-03 0,04670608 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 8,692E-03 0,04657031 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 8,692E-03 0,04643532 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 8,692E-03 0,04630111 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 8,692E-03 0,04616768 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 8,692E-03 0,04603501 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 8,692E-03 0,04590311 ! arginine metabolic process GO:0006525 6 6 0,000 8,692E-03 0,04577196 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 8,692E-03 0,04564155 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 8,692E-03 0,04551189 ! glutamate catabolic process GO:0006538 7 6 0,000 8,692E-03 0,04538296 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 8,692E-03 0,04525476 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 8,692E-03 0,04512728 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 8,692E-03 0,04500052 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 8,692E-03 0,04487447 ! ER overload response GO:0006983 6 6 0,000 8,692E-03 0,04474912 ! V(D)J recombination GO:0033151 6 6 0,000 8,692E-03 0,04462447 ! focal adhesion formation GO:0048041 7 6 0,000 8,692E-03 0,04450051 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 8,692E-03 0,04437724 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 8,692E-03 0,04425465 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 8,692E-03 0,04413274 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 8,692E-03 0,0440115 ! regulation of heart rate GO:0002027 6 6 0,000 8,692E-03 0,04389092 ! lipid digestion GO:0044241 6 6 0,000 8,692E-03 0,043771 ! asymmetric protein localization GO:0008105 6 6 0,000 8,692E-03 0,04365173 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 8,692E-03 0,04353311 ! phagocytosis, engulfment GO:0006911 6 6 0,000 8,692E-03 0,04341514 ! Rac protein signal transduction GO:0016601 6 6 0,000 8,692E-03 0,0432978 ! regulation of vascular permeability GO:0043114 6 6 0,000 8,692E-03 0,04318109 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 8,692E-03 0,04306501 ! ruffle organization GO:0031529 6 6 0,000 8,692E-03 0,04294956 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 8,692E-03 0,04283472 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 8,692E-03 0,04272049 ! retinoic acid metabolic process GO:0042573 6 6 0,000 8,692E-03 0,04260687 ! neutral amino acid transport GO:0015804 6 6 0,000 8,692E-03 0,04249386 ! L-amino acid transport GO:0015807 6 6 0,000 8,692E-03 0,04238144 ! bone mineralization GO:0030282 6 6 0,000 8,692E-03 0,04226962 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 8,692E-03 0,04215838 ! negative regulation of ossification GO:0030279 6 6 0,000 8,692E-03 0,04204773 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 8,692E-03 0,04193766 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 8,692E-03 0,04182816 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 8,692E-03 0,04171923 ! purine base biosynthetic process GO:0009113 6 6 0,000 8,692E-03 0,04161087 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 8,692E-03 0,04150307 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 8,692E-03 0,04139583 ! regulation of phagocytosis GO:0050764 6 6 0,000 8,692E-03 0,04128914 ! regulation of organ growth GO:0046620 6 6 0,000 8,692E-03 0,04118299 ! regulation of circadian rhythm GO:0042752 6 6 0,000 8,692E-03 0,0410774 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 8,692E-03 0,04097234 ! response to dsRNA GO:0043331 6 6 0,000 8,692E-03 0,04086782 ! DNA unwinding during replication GO:0006268 6 6 0,000 8,692E-03 0,04076383 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 8,692E-03 0,04066037 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 8,692E-03 0,04055743 ! genitalia development GO:0048806 6 6 0,000 8,692E-03 0,04045501 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 8,692E-03 0,04035311 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 8,692E-03 0,04025172 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 8,692E-03 0,04015084 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 8,692E-03 0,04005046 ! multicellular organismal aging GO:0010259 6 6 0,000 8,692E-03 0,03995059 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 8,692E-03 0,03985121 ! erythrocyte development GO:0048821 6 6 0,000 8,692E-03 0,03975232 ! renal water homeostasis GO:0003091 6 6 0,000 8,692E-03 0,03965392 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 8,692E-03 0,03955601 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 8,692E-03 0,03945858 ! ribosome assembly GO:0042255 6 6 0,000 8,692E-03 0,03936163 ! diencephalon development GO:0021536 6 6 0,000 8,692E-03 0,03926516 ! fucose catabolic process GO:0019317 6 6 0,000 8,692E-03 0,03916916 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 8,692E-03 0,03907362 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 8,692E-03 0,03897855 ! regulation of lipid transport GO:0032368 6 6 0,000 8,692E-03 0,03888394 ! regulation of cell division GO:0051302 6 6 0,000 8,692E-03 0,03878979 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 8,692E-03 0,0386961 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 8,692E-03 0,03860286 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 8,692E-03 0,03851006 ! salivary gland morphogenesis GO:0007435 6 6 0,000 8,692E-03 0,03841771 ! neuroblast proliferation GO:0007405 6 6 0,000 8,692E-03 0,0383258 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 8,692E-03 0,03823433 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 8,692E-03 0,0381433 ! regulation of glucose transport GO:0010827 6 6 0,000 8,692E-03 0,0380527 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 8,692E-03 0,03796252 ! methionine biosynthetic process GO:0009086 6 6 0,000 8,692E-03 0,03787278 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 8,692E-03 0,03778346 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 8,692E-03 0,03769455 ! thymus development GO:0048538 6 6 0,000 8,692E-03 0,03760607 ! lymph node development GO:0048535 6 6 0,000 8,692E-03 0,037518 ! organic cation transport GO:0015695 6 6 0,000 8,692E-03 0,03743034 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 8,692E-03 0,03734309 ! regulation of RNA splicing GO:0043484 6 6 0,000 8,692E-03 0,03725624 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 8,692E-03 0,0371698 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 8,692E-03 0,03708376 ! sperm-egg recognition GO:0035036 7 6 0,000 8,692E-03 0,03699812 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 8,692E-03 0,03691287 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 8,692E-03 0,03682801 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 8,692E-03 0,03674354 ! alditol metabolic process GO:0019400 6 6 0,000 8,692E-03 0,03665946 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 8,692E-03 0,03657576 ! regulation of amino acid transport GO:0051955 6 6 0,000 8,692E-03 0,03649245 ! maternal placenta development GO:0001893 6 6 0,000 8,692E-03 0,03640951 ! regulation of embryonic development GO:0045995 6 6 0,000 8,692E-03 0,03632695 ! negative regulation of immune effector process GO:0002698 6 6 0,000 8,692E-03 0,03624476 ! localization within membrane GO:0051668 6 6 0,000 8,692E-03 0,03616295 ! response to hormone stimulus GO:0009725 102 100 1,000 8,724E-03 0,03621128 ! respiratory burst GO:0045730 7 7 0,000 0,01013456 0,04197303 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,01013456 0,04187892 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,01013456 0,04178523 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,01013456 0,04169196 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,01013456 0,0415991 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,01013456 0,04150666 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,01013456 0,04141463 ! regulation of chemokine production GO:0032642 7 7 0,000 0,01013456 0,041323 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,01013456 0,04123178 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,01013456 0,04114096 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,01013456 0,04105054 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,01013456 0,04096052 ! gene silencing by RNA GO:0031047 7 7 0,000 0,01013456 0,04087089 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,01013456 0,04078165 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,01013456 0,0406928 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,01013456 0,04060434 ! axis specification GO:0009798 7 7 0,000 0,01013456 0,04051626 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,01013456 0,04042856 ! visual behavior GO:0007632 7 7 0,000 0,01013456 0,04034125 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,01013456 0,0402543 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,01013456 0,04016773 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,01013456 0,04008154 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,01013456 0,03999571 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,01013456 0,03991025 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,01013456 0,03982515 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,01013456 0,03974042 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,01013456 0,03965604 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,01013456 0,03957203 ! digestive system development GO:0055123 7 7 0,000 0,01013456 0,03948837 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,01013456 0,03940506 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,01013456 0,0393221 ! protein targeting to ER GO:0045047 8 7 0,000 0,01013456 0,03923949 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,01013456 0,03915723 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,01013456 0,03907531 ! endoderm development GO:0007492 7 7 0,000 0,01013456 0,03899373 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,01013456 0,03891249 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,01013456 0,03883159 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,01013456 0,03875103 ! response to hexose stimulus GO:0009746 7 7 0,000 0,01013456 0,0386708 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,01013456 0,0385909 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,01013456 0,03851133 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,01013456 0,03843209 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,01013456 0,03835318 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,01013456 0,03827458 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,01013456 0,03819631 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,01013456 0,03811836 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,01013456 0,03804073 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,01013456 0,03796341 ! response to X-ray GO:0010165 7 7 0,000 0,01013456 0,0378864 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,01013456 0,03780971 ! UV protection GO:0009650 7 7 0,000 0,01013456 0,03773333 ! DNA integration GO:0015074 7 7 0,000 0,01013456 0,03765725 ! myofibril assembly GO:0030239 7 7 0,000 0,01013456 0,03758148 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,01013456 0,03750602 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,01013456 0,03743086 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,01013456 0,03735599 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,01013456 0,03728143 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,01013456 0,03720716 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,01013456 0,03713319 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,01013456 0,03705952 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,01013456 0,03698613 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,01013456 0,03691304 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,01013456 0,03684023 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,01013456 0,03676771 ! axon cargo transport GO:0008088 7 7 0,000 0,01013456 0,03669547 ! eating behavior GO:0042755 7 7 0,000 0,01013456 0,03662352 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,01013456 0,03655185 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,01013456 0,03648046 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,01013456 0,03640935 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,01013456 0,03633852 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,01013456 0,03626795 ! cranial nerve development GO:0021545 7 7 0,000 0,01013456 0,03619767 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,01013456 0,03612765 ! induction of an organ GO:0001759 7 7 0,000 0,01013456 0,03605791 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,01013456 0,03598843 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,01013456 0,03591922 ! autonomic nervous system development GO:0048483 7 7 0,000 0,01013456 0,03585028 ! intracellular lipid transport GO:0032365 7 7 0,000 0,01013456 0,0357816 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,01013456 0,03571319 ! platelet activation GO:0030168 8 7 0,000 0,01013456 0,03564503 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,01013456 0,03557714 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,01013456 0,0355095 ! natural killer cell activation GO:0030101 7 7 0,000 0,01013456 0,03544212 ! response to gamma radiation GO:0010332 8 7 0,000 0,01013456 0,03537499 ! NADP metabolic process GO:0006739 7 7 0,000 0,01013456 0,03530812 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,01013456 0,0352415 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,01013456 0,03517514 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,01013456 0,03510902 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,01013456 0,03504315 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,01013456 0,03497752 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,01013456 0,03491214 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,01013456 0,03484701 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,01013456 0,03478212 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,01013456 0,03471747 ! cell-cell recognition GO:0009988 8 7 0,000 0,01013456 0,03465306 ! hormone catabolic process GO:0042447 7 7 0,000 0,01013456 0,03458888 ! dopamine metabolic process GO:0042417 7 7 0,000 0,01013456 0,03452495 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,01013456 0,03446125 ! oxygen transport GO:0015671 7 7 0,000 0,01013456 0,03439778 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,01013456 0,03433455 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,01013456 0,03427155 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,01013456 0,03420879 ! regulation of axon extension GO:0030516 7 7 0,000 0,01013456 0,03414625 ! cell killing GO:0001906 7 7 0,000 0,01013456 0,03408394 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,01013456 0,03402185 ! adult feeding behavior GO:0008343 7 7 0,000 0,01013456 0,03395999 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,01013456 0,03389836 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,01013456 0,03383695 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,01013456 0,03377576 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,01013456 0,0337148 ! response to cold GO:0009409 7 7 0,000 0,01013456 0,03365405 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,01157478 0,0383675 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,01157478 0,03829861 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,01157478 0,03822998 ! positive regulation of translation GO:0045727 8 8 0,000 0,01157478 0,03816159 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,01157478 0,03809344 ! superoxide anion generation GO:0042554 8 8 0,000 0,01157478 0,03802554 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,01157478 0,03795788 ! cGMP metabolic process GO:0046068 8 8 0,000 0,01157478 0,03789046 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,01157478 0,03782328 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,01157478 0,03775633 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,01157478 0,03768963 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,01157478 0,03762315 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,01157478 0,03755692 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,01157478 0,03749091 ! zinc ion transport GO:0006829 8 8 0,000 0,01157478 0,03742514 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,01157478 0,03735959 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,01157478 0,03729428 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,01157478 0,03722919 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,01157478 0,03716433 ! lipid localization GO:0010876 8 8 0,000 0,01157478 0,0370997 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,01157478 0,03703529 ! response to cAMP GO:0051591 8 8 0,000 0,01157478 0,03697111 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,01157478 0,03690714 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,01157478 0,0368434 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,01157478 0,03677988 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,01157478 0,03671657 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,01157478 0,03665348 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,01157478 0,03659061 ! sensory perception of taste GO:0050909 8 8 0,000 0,01157478 0,03652796 ! organelle fusion GO:0048284 8 8 0,000 0,01157478 0,03646552 ! pancreas development GO:0031016 8 8 0,000 0,01157478 0,03640329 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,01157478 0,03634127 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,01157478 0,03627947 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,01157478 0,03621787 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,01157478 0,03615649 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,01157478 0,03609531 ! sperm motility GO:0030317 8 8 0,000 0,01157478 0,03603434 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,01157478 0,03597357 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,01157478 0,03591301 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,01157478 0,03585265 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,01157478 0,0357925 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,01157478 0,03573254 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01157478 0,03567279 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,01157478 0,03561324 ! Golgi organization GO:0007030 8 8 0,000 0,01157478 0,03555388 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,01157478 0,03549472 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,01157478 0,03543576 ! fructose metabolic process GO:0006000 8 8 0,000 0,01157478 0,035377 ! mannose metabolic process GO:0006013 9 8 0,000 0,01157478 0,03531842 ! NAD metabolic process GO:0019674 8 8 0,000 0,01157478 0,03526005 ! sex determination GO:0007530 8 8 0,000 0,01157478 0,03520186 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,01157478 0,03514387 ! plasma membrane fusion GO:0045026 8 8 0,000 0,01157478 0,03508607 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,01157478 0,03502845 ! response to fungus GO:0009620 8 8 0,000 0,01157478 0,03497103 ! stem cell differentiation GO:0048863 8 8 0,000 0,01157478 0,03491379 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,01157478 0,03485675 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,01157478 0,03479988 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,01157478 0,03474321 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,01157478 0,03468671 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01157478 0,0346304 ! regulation of vasodilation GO:0042312 8 8 0,000 0,01157478 0,03457428 ! vasoconstriction GO:0042310 8 8 0,000 0,01157478 0,03451833 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,01157478 0,03446257 ! muscle cell development GO:0055001 8 8 0,000 0,01157478 0,03440698 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,01157478 0,03435158 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,01157478 0,03429635 ! sensory perception of pain GO:0019233 8 8 0,000 0,01157478 0,0342413 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,01157478 0,03418642 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,01157478 0,03413173 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,01157478 0,0340772 ! chromatin silencing GO:0006342 8 8 0,000 0,01157478 0,03402285 ! tissue regeneration GO:0042246 8 8 0,000 0,01157478 0,03396868 ! salivary gland development GO:0007431 8 8 0,000 0,01157478 0,03391467 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,01157478 0,03386084 ! T cell homeostasis GO:0043029 8 8 0,000 0,01157478 0,03380718 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,01157478 0,03375368 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,01157478 0,03370036 ! water homeostasis GO:0030104 8 8 0,000 0,01157478 0,03364721 ! cofactor transport GO:0051181 8 8 0,000 0,01157478 0,03359422 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,01157478 0,0335414 ! acid secretion GO:0046717 8 8 0,000 0,01157478 0,03348874 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,01157478 0,03343625 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,01157478 0,03338393 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,01157478 0,03333176 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,01157478 0,03327976 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,01157478 0,03322793 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,01157478 0,03317625 ! regulation of RNA stability GO:0043487 8 8 0,000 0,01157478 0,03312473 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,01157478 0,03307338 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,01157478 0,03302218 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,01157478 0,03297114 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,01157478 0,03292026 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,01157478 0,03286953 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,01157478 0,03281897 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,01157478 0,03276855 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,01157478 0,03271829 ! developmental induction GO:0031128 8 8 0,000 0,01157478 0,03266819 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,01157478 0,03261824 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,01157478 0,03256844 ! actin filament polymerization GO:0030041 9 8 0,000 0,01157478 0,03251879 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,01157478 0,0324693 ! peptide hormone processing GO:0016486 8 8 0,000 0,01157478 0,03241995 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,01157478 0,03237076 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,01157478 0,03232171 ! lactation GO:0007595 10 9 0,000 0,01301312 0,03628318 ! embryonic pattern specification GO:0009880 10 9 0,000 0,01301312 0,03622837 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,01301312 0,03617373 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,01301312 0,03611925 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,01301312 0,03606494 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,01301312 0,03601079 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,01301312 0,0359568 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,01301312 0,03590297 ! viral genome replication GO:0019079 9 9 0,000 0,01301312 0,0358493 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,01301312 0,0357958 ! copper ion transport GO:0006825 9 9 0,000 0,01301312 0,03574245 ! lipid phosphorylation GO:0046834 9 9 0,000 0,01301312 0,03568926 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,01301312 0,03563623 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,01301312 0,03558336 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,01301312 0,03553064 ! RNA polyadenylation GO:0043631 9 9 0,000 0,01301312 0,03547808 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,01301312 0,03542568 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,01301312 0,03537343 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,01301312 0,03532133 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,01301312 0,03526939 ! phospholipid efflux GO:0033700 9 9 0,000 0,01301312 0,0352176 ! response to alkaloid GO:0043279 10 9 0,000 0,01301312 0,03516596 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,01301312 0,03511447 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,01301312 0,03506313 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,01301312 0,03501195 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,01301312 0,03496091 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,01301312 0,03491002 ! response to ethanol GO:0045471 9 9 0,000 0,01301312 0,03485928 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,01301312 0,03480868 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,01301312 0,03475824 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,01301312 0,03470794 ! methionine metabolic process GO:0006555 9 9 0,000 0,01301312 0,03465778 ! glutamine metabolic process GO:0006541 9 9 0,000 0,01301312 0,03460777 ! cerebral cortex development GO:0021987 9 9 0,000 0,01301312 0,0345579 ! response to osmotic stress GO:0006970 9 9 0,000 0,01301312 0,03450818 ! pigmentation during development GO:0048066 9 9 0,000 0,01301312 0,0344586 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,01301312 0,03440916 ! central nervous system neuron development GO:0021954 10 9 0,000 0,01301312 0,03435986 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,01301312 0,03431071 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,01301312 0,03426169 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,01301312 0,03421282 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,01301312 0,03416408 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,01301312 0,03411548 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,01301312 0,03406702 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,01301312 0,0340187 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,01301312 0,03397051 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,01301312 0,03392247 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,01301312 0,03387455 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,01301312 0,03382677 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,01301312 0,03377913 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,01301312 0,03373162 ! DNA replication initiation GO:0006270 9 9 0,000 0,01301312 0,03368425 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,01301312 0,033637 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,01301312 0,03358989 ! regulation of cellular pH GO:0030641 9 9 0,000 0,01301312 0,03354291 ! histone acetylation GO:0016573 9 9 0,000 0,01301312 0,03349607 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,01301312 0,03344935 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,01301312 0,03340276 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,01301312 0,03335631 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,01301312 0,03330998 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,01301312 0,03326378 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,01301312 0,03321771 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,01301312 0,03317176 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,01301312 0,03312594 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,01301312 0,03308025 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,01301312 0,03303469 ! collagen catabolic process GO:0030574 9 9 0,000 0,01301312 0,03298925 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,01301312 0,03294393 ! purine base metabolic process GO:0006144 9 9 0,000 0,01301312 0,03289874 ! gas transport GO:0015669 9 9 0,000 0,01301312 0,03285368 ! cholesterol efflux GO:0033344 9 9 0,000 0,01301312 0,03280873 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,01301312 0,03276391 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,01301312 0,03271921 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,01301312 0,03267464 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,01301312 0,03263018 ! defense response to virus GO:0051607 9 9 0,000 0,01301312 0,03258585 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,01301312 0,03254163 ! actin filament-based movement GO:0030048 9 9 0,000 0,01301312 0,03249754 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,01301312 0,03245356 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01444957 0,03598725 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01444957 0,03593869 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01444957 0,03589025 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,01444957 0,03584195 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01444957 0,03579377 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01444957 0,03574573 ! neuron maturation GO:0042551 10 10 0,000 0,01444957 0,03569781 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01444957 0,03565002 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01444957 0,03560236 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01444957 0,03555483 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01444957 0,03550742 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01444957 0,03546014 ! hormone secretion GO:0046879 10 10 0,000 0,01444957 0,03541299 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01444957 0,03536596 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01444957 0,03531905 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,01444957 0,03527227 ! inositol metabolic process GO:0006020 10 10 0,000 0,01444957 0,03522562 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01444957 0,03517908 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01444957 0,03513267 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01444957 0,03508639 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01444957 0,03504022 ! glial cell development GO:0021782 10 10 0,000 0,01444957 0,03499417 ! phototransduction GO:0007602 11 10 0,000 0,01444957 0,03494825 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01444957 0,03490245 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01444957 0,03485676 ! fat cell differentiation GO:0045444 10 10 0,000 0,01444957 0,0348112 ! myoblast differentiation GO:0045445 10 10 0,000 0,01444957 0,03476575 ! centrosome cycle GO:0007098 10 10 0,000 0,01444957 0,03472043 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01444957 0,03467522 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01444957 0,03463013 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01444957 0,03458515 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01444957 0,03454029 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01444957 0,03449555 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,01444957 0,03445093 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01444957 0,03440642 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01444957 0,03436202 ! plasma membrane organization GO:0007009 10 10 0,000 0,01444957 0,03431774 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01444957 0,03427357 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01444957 0,03422952 ! lysosomal transport GO:0007041 10 10 0,000 0,01444957 0,03418558 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01444957 0,03414175 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01444957 0,03409804 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,01444957 0,03405443 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,01444957 0,03401094 ! exocrine system development GO:0035272 10 10 0,000 0,01444957 0,03396756 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01444957 0,03392429 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01444957 0,03388113 ! embryo implantation GO:0007566 11 10 0,000 0,01444957 0,03383808 ! regulation of protein binding GO:0043393 11 10 0,000 0,01444957 0,03379513 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01444957 0,0337523 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01444957 0,03370958 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,01444957 0,03366696 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01444957 0,03362445 ! protein export from nucleus GO:0006611 10 10 0,000 0,01444957 0,03358205 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01444957 0,03353976 ! cytolysis GO:0019835 10 10 0,000 0,01444957 0,03349757 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01444957 0,03345549 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01444957 0,03341351 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01444957 0,03337164 ! histone deacetylation GO:0016575 10 10 0,000 0,01444957 0,03332987 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01444957 0,03328821 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01444957 0,03324665 ! gland morphogenesis GO:0022612 10 10 0,000 0,01444957 0,03320519 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01444957 0,03316384 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01444957 0,03312259 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01444957 0,03308145 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01444957 0,0330404 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,01444957 0,03299946 ! regulation of epidermis development GO:0045682 10 10 0,000 0,01444957 0,03295862 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01444957 0,03291788 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,01444957 0,03287724 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01444957 0,0328367 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01444957 0,03279626 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01444957 0,03275592 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01444957 0,03271568 ! nerve development GO:0021675 10 10 0,000 0,01444957 0,03267554 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,01444957 0,0326355 ! gut development GO:0048565 10 10 0,000 0,01444957 0,03259555 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01444957 0,0325557 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,01444957 0,03251595 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01444957 0,0324763 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01444957 0,03243674 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01444957 0,03239728 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01444957 0,03235792 ! protein stabilization GO:0050821 10 10 0,000 0,01444957 0,03231865 ! protein secretion GO:0009306 11 11 0,000 0,01588415 0,03548422 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01588415 0,03544126 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01588415 0,03539841 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01588415 0,03535565 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01588415 0,035313 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01588415 0,03527046 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,01588415 0,03522802 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01588415 0,03518567 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01588415 0,03514343 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,01588415 0,0351013 ! signal complex assembly GO:0007172 11 11 0,000 0,01588415 0,03505926 ! microtubule-based transport GO:0010970 11 11 0,000 0,01588415 0,03501732 ! endothelial cell migration GO:0043542 11 11 0,000 0,01588415 0,03497549 ! peroxisomal transport GO:0043574 11 11 0,000 0,01588415 0,03493375 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01588415 0,03489211 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,01588415 0,03485057 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01588415 0,03480913 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01588415 0,03476779 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01588415 0,03472655 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01588415 0,0346854 ! T cell proliferation GO:0042098 11 11 0,000 0,01588415 0,03464436 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01588415 0,03460341 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01588415 0,03456255 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,01588415 0,03452179 ! spinal cord development GO:0021510 11 11 0,000 0,01588415 0,03448113 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01588415 0,03444057 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01588415 0,0344001 ! cellular response to starvation GO:0009267 11 11 0,000 0,01588415 0,03435972 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01588415 0,03431944 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,01588415 0,03427925 ! digestive system process GO:0022600 11 11 0,000 0,01588415 0,03423916 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01588415 0,03419916 ! fucose metabolic process GO:0006004 11 11 0,000 0,01588415 0,03415925 ! membrane budding GO:0006900 11 11 0,000 0,01588415 0,03411944 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,01588415 0,03407972 ! monoamine transport GO:0015844 11 11 0,000 0,01588415 0,03404009 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01588415 0,03400056 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01588415 0,03396111 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01588415 0,03392176 ! body fluid secretion GO:0007589 11 11 0,000 0,01588415 0,0338825 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01588415 0,03384333 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,01588415 0,03380425 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01588415 0,03376526 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01588415 0,03372636 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01588415 0,03368755 ! membrane depolarization GO:0051899 11 11 0,000 0,01588415 0,03364883 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01588415 0,0336102 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01588415 0,03357165 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,01588415 0,0335332 ! oogenesis GO:0048477 11 11 0,000 0,01588415 0,03349483 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01588415 0,03345655 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01588415 0,03341836 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,01588415 0,03338025 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,01588415 0,03334223 ! muscle maintenance GO:0046716 12 11 0,000 0,01588415 0,0333043 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01588415 0,03326646 ! hindbrain development GO:0030902 11 11 0,000 0,01588415 0,0332287 ! steroid catabolic process GO:0006706 11 11 0,000 0,01588415 0,03319102 ! endocrine process GO:0050886 11 11 0,000 0,01588415 0,03315343 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01588415 0,03311593 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01588415 0,03307851 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01588415 0,03304118 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,01588415 0,03300392 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01588415 0,03296676 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,01731684 0,03589981 ! translational initiation GO:0006413 12 12 0,000 0,01731684 0,03585947 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,01731684 0,03581923 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,01731684 0,03577907 ! initiation of viral infection GO:0019059 12 12 0,000 0,01731684 0,03573901 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,01731684 0,03569903 ! iron ion transport GO:0006826 13 12 0,000 0,01731684 0,03565914 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,01731684 0,03561934 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,01731684 0,03557963 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,01731684 0,03554001 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,01731684 0,03550048 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,01731684 0,03546104 ! collagen metabolic process GO:0032963 12 12 0,000 0,01731684 0,03542168 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,01731684 0,03538241 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,01731684 0,03534322 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,01731684 0,03530413 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,01731684 0,03526512 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,01731684 0,03522619 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,01731684 0,03518736 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,01731684 0,0351486 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,01731684 0,03510994 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,01731684 0,03507135 ! retinoid metabolic process GO:0001523 12 12 0,000 0,01731684 0,03503286 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,01731684 0,03499444 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,01731684 0,03495611 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,01731684 0,03491787 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,01731684 0,03487971 ! acute-phase response GO:0006953 12 12 0,000 0,01731684 0,03484163 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01731684 0,03480363 ! vacuolar transport GO:0007034 12 12 0,000 0,01731684 0,03476572 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,01731684 0,03472789 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,01731684 0,03469014 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,01731684 0,03465248 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,01731684 0,03461489 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,01731684 0,03457739 ! male gonad development GO:0008584 12 12 0,000 0,01731684 0,03453997 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,01731684 0,03450263 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,01731684 0,03446537 ! renal system process GO:0003014 12 12 0,000 0,01731684 0,03442819 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,01731684 0,03439109 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,01731684 0,03435407 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,01731684 0,03431713 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,01731684 0,03428027 ! pallium development GO:0021543 13 12 0,000 0,01731684 0,03424349 ! cell fate determination GO:0001709 12 12 0,000 0,01731684 0,03420679 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,01731684 0,03417016 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,01731684 0,03413362 ! somitogenesis GO:0001756 13 12 0,000 0,01731684 0,03409715 ! G1 phase GO:0051318 13 12 0,000 0,01731684 0,03406076 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,01731684 0,03402445 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,01731684 0,03398821 ! detection of light stimulus GO:0009583 13 12 0,000 0,01731684 0,03395205 ! synaptogenesis GO:0007416 12 12 0,000 0,01731684 0,03391597 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,01731684 0,03387997 ! hormone transport GO:0009914 12 12 0,000 0,01731684 0,03384404 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,01731684 0,03380819 ! heme biosynthetic process GO:0006783 12 12 0,000 0,01731684 0,03377241 ! spermatid differentiation GO:0048515 13 12 0,000 0,01731684 0,03373671 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,01731684 0,03370109 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,01731684 0,03366554 ! neural tube closure GO:0001843 13 12 0,000 0,01731684 0,03363006 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,01731684 0,03359466 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,01731684 0,03355934 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,01731684 0,03352409 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,01874765 0,03625595 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,01874765 0,03621795 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,01874765 0,03618002 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,01874765 0,03614218 ! phenol metabolic process GO:0018958 13 13 0,000 0,01874765 0,03610441 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,01874765 0,03606672 ! gluconeogenesis GO:0006094 13 13 0,000 0,01874765 0,03602912 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,01874765 0,03599159 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,01874765 0,03595413 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,01874765 0,03591676 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,01874765 0,03587946 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,01874765 0,03584224 ! regeneration GO:0031099 13 13 0,000 0,01874765 0,0358051 ! keratinization GO:0031424 13 13 0,000 0,01874765 0,03576804 ! post-embryonic development GO:0009791 14 13 0,000 0,01874765 0,03573105 ! patterning of blood vessels GO:0001569 13 13 0,000 0,01874765 0,03569413 ! vasculogenesis GO:0001570 13 13 0,000 0,01874765 0,0356573 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,01874765 0,03562054 ! regulation of innate immune response GO:0045088 13 13 0,000 0,01874765 0,03558385 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,01874765 0,03554725 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,01874765 0,03551071 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,01874765 0,03547425 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,01874765 0,03543787 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,01874765 0,03540156 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,01874765 0,03536532 ! autophagy GO:0006914 13 13 0,000 0,01874765 0,03532916 ! receptor metabolic process GO:0043112 14 13 0,000 0,01874765 0,03529308 ! actin filament bundle formation GO:0051017 13 13 0,000 0,01874765 0,03525706 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,01874765 0,03522112 ! ureteric bud development GO:0001657 13 13 0,000 0,01874765 0,03518526 ! cell aging GO:0007569 13 13 0,000 0,01874765 0,03514946 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,01874765 0,03511374 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,01874765 0,03507809 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,01874765 0,03504252 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,01874765 0,03500701 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,01874765 0,03497158 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,01874765 0,03493622 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,01874765 0,03490093 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,01874765 0,03486571 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,01874765 0,03483057 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,01874765 0,03479549 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,01874765 0,03476049 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,01874765 0,03472555 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,01874765 0,03469068 ! vasodilation GO:0042311 14 13 0,000 0,01874765 0,03465589 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,01874765 0,03462116 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,01874765 0,03458651 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,01874765 0,03455192 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,01874765 0,0345174 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,01874765 0,03448296 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,01874765 0,03444858 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,01874765 0,03441427 ! immunoglobulin production GO:0002377 13 13 0,000 0,01874765 0,03438002 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,01874765 0,03434585 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,01874765 0,03431174 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,01874765 0,0342777 ! cell-cell junction organization GO:0045216 13 13 0,000 0,01874765 0,03424373 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,01874765 0,03420982 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,01874765 0,03417599 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,01874765 0,03414222 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,01874765 0,03410851 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,01874765 0,03407487 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,01874765 0,0340413 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,01874765 0,0340078 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,01874765 0,03397436 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,01874765 0,03394098 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,01874765 0,03390768 ! blastocyst development GO:0001824 13 13 0,000 0,01874765 0,03387443 ! telomere organization GO:0032200 13 13 0,000 0,01874765 0,03384126 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,01874765 0,03380814 ! regulation of amine transport GO:0051952 13 13 0,000 0,01874765 0,03377509 ! tissue homeostasis GO:0001894 13 13 0,000 0,01874765 0,03374211 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,01874765 0,03370919 ! protein tetramerization GO:0051262 13 13 0,000 0,01874765 0,03367634 ! neuron fate commitment GO:0048663 14 14 0,000 0,02017659 0,03620784 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,02017659 0,03617262 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,02017659 0,03613747 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,02017659 0,03610239 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,02017659 0,03606737 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,02017659 0,03603242 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,02017659 0,03599754 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,02017659 0,03596272 ! protein amino acid acylation GO:0043543 14 14 0,000 0,02017659 0,03592798 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,02017659 0,0358933 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,02017659 0,03585869 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,02017659 0,03582414 ! vesicle docking GO:0048278 14 14 0,000 0,02017659 0,03578966 ! superoxide metabolic process GO:0006801 15 14 0,000 0,02017659 0,03575525 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,02017659 0,0357209 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,02017659 0,03568662 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,02017659 0,0356524 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,02017659 0,03561825 ! hair cycle GO:0042633 14 14 0,000 0,02017659 0,03558417 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,02017659 0,03555015 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,02017659 0,0355162 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,02017659 0,03548231 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,02017659 0,03544848 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,02017659 0,03541472 ! lysosome organization GO:0007040 14 14 0,000 0,02017659 0,03538102 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,02017659 0,03534739 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,02017659 0,03531382 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,02017659 0,03528032 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,02017659 0,03524688 ! primary neural tube formation GO:0014020 15 14 0,000 0,02017659 0,0352135 ! peptide cross-linking GO:0018149 14 14 0,000 0,02017659 0,03518019 ! regulation of behavior GO:0050795 14 14 0,000 0,02017659 0,03514693 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,02017659 0,03511375 ! base-excision repair GO:0006284 14 14 0,000 0,02017659 0,03508062 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,02017659 0,03504756 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,02017659 0,03501455 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,02017659 0,03498161 ! formation of primary germ layer GO:0001704 14 14 0,000 0,02017659 0,03494874 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,02017659 0,03491592 ! collagen fibril organization GO:0030199 14 14 0,000 0,02017659 0,03488317 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,02017659 0,03485047 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,02017659 0,03481784 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,02017659 0,03478527 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,02017659 0,03475276 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,02017659 0,03472031 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,02017659 0,03468793 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,02017659 0,0346556 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,02017659 0,03462333 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,02017659 0,03459112 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,02160366 0,03700329 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,02160366 0,03696893 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,02160366 0,03693464 ! positive regulation of ossification GO:0045778 15 15 0,000 0,02160366 0,03690041 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,02160366 0,03686624 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,02160366 0,03683214 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,02160366 0,0367981 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,02160366 0,03676412 ! response to vitamin GO:0033273 15 15 0,000 0,02160366 0,0367302 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,02160366 0,03669635 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,02160366 0,03666256 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,02160366 0,03662883 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,02160366 0,03659516 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,02160366 0,03656156 ! ovarian follicle development GO:0001541 15 15 0,000 0,02160366 0,03652802 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,02160366 0,03649454 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,02160366 0,03646112 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,02160366 0,03642776 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,02160366 0,03639446 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,02160366 0,03636122 ! heme metabolic process GO:0042168 15 15 0,000 0,02160366 0,03632805 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,02160366 0,03629493 ! chromosome condensation GO:0030261 15 15 0,000 0,02160366 0,03626188 ! response to starvation GO:0042594 15 15 0,000 0,02160366 0,03622888 ! response to ionizing radiation GO:0010212 16 15 0,000 0,02160366 0,03619594 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,02160366 0,03616307 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,02160366 0,03613025 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,02160366 0,0360975 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,02160366 0,0360648 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,02160366 0,03603216 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,02160366 0,03599958 ! phospholipid transport GO:0015914 15 15 0,000 0,02160366 0,03596706 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,02160366 0,0359346 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,02160366 0,0359022 ! glutathione metabolic process GO:0006749 16 15 0,000 0,02160366 0,03586985 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,02160366 0,03583757 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,02160366 0,03580534 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,02160366 0,03577317 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,02160366 0,03574106 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,02160366 0,035709 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,02160366 0,03567701 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,02160366 0,03564507 ! protein homooligomerization GO:0051260 15 15 0,000 0,02160366 0,03561318 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,02160366 0,03558136 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,02302885 0,0378948 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,02302885 0,03786099 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,02302885 0,03782725 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,02302885 0,03779356 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,02302885 0,03775994 ! learning GO:0007612 16 16 0,000 0,02302885 0,03772638 ! circadian rhythm GO:0007623 16 16 0,000 0,02302885 0,03769287 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,02302885 0,03765943 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,02302885 0,03762604 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,02302885 0,03759271 ! vacuole organization GO:0007033 16 16 0,000 0,02302885 0,03755945 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,02302885 0,03752624 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,02302885 0,03749309 ! vesicle targeting GO:0006903 17 16 0,000 0,02302885 0,03745999 ! segmentation GO:0035282 17 16 0,000 0,02302885 0,03742696 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,02302885 0,03739399 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,02302885 0,03736107 ! iron ion homeostasis GO:0055072 16 16 0,000 0,02302885 0,03732821 ! positive regulation of cell development GO:0010720 16 16 0,000 0,02302885 0,03729541 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,02302885 0,03726266 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,02302885 0,03722998 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,02302885 0,03719735 ! cell fate specification GO:0001708 16 16 0,000 0,02302885 0,03716478 ! pentose metabolic process GO:0019321 16 16 0,000 0,02302885 0,03713226 ! fatty acid transport GO:0015908 16 16 0,000 0,02302885 0,0370998 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,02302885 0,0370674 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,02302885 0,03703506 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,02302885 0,03700277 ! cofactor catabolic process GO:0051187 16 16 0,000 0,02302885 0,03697053 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,02302885 0,03693836 ! polyol metabolic process GO:0019751 16 16 0,000 0,02302885 0,03690624 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,02302885 0,03687417 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,02302885 0,03684216 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,02302885 0,03681021 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,02302885 0,03677831 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,02302885 0,03674647 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,02302885 0,03671468 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,02302885 0,03668295 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,02302885 0,03665127 ! regulation of coagulation GO:0050818 17 16 0,000 0,02302885 0,03661965 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,02445218 0,03884945 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,02445218 0,03881599 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,02445218 0,03878258 ! myelination GO:0042552 17 17 0,000 0,02445218 0,03874924 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,02445218 0,03871595 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,02445218 0,03868272 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,02445218 0,03864954 ! leukocyte adhesion GO:0007159 17 17 0,000 0,02445218 0,03861642 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,02445218 0,03858336 ! sensory perception of smell GO:0007608 17 17 0,000 0,02445218 0,03855035 ! glucose transport GO:0015758 17 17 0,000 0,02445218 0,0385174 ! cell junction assembly GO:0034329 18 17 0,000 0,02445218 0,03848451 ! tissue remodeling GO:0048771 17 17 0,000 0,02445218 0,03845168 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,02445218 0,03841889 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,02445218 0,03838617 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,02445218 0,0383535 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,02445218 0,03832089 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,02445218 0,03828833 ! neural crest cell development GO:0014032 19 17 0,000 0,02445218 0,03825583 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,02445218 0,03822338 ! negative regulation of cell development GO:0010721 18 17 0,000 0,02445218 0,03819099 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,02445218 0,03815865 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,02445218 0,03812637 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,02445218 0,03809414 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,02445218 0,03806196 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,02445218 0,03802984 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,02445218 0,03799778 ! pigmentation GO:0043473 17 17 0,000 0,02445218 0,03796577 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,02445218 0,03793381 ! adult locomotory behavior GO:0008344 17 17 0,000 0,02445218 0,0379019 ! embryonic organ development GO:0048568 17 17 0,000 0,02445218 0,03787005 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,02445218 0,03783826 ! liver development GO:0001889 17 17 0,000 0,02445218 0,03780651 ! gene silencing GO:0016458 17 17 0,000 0,02445218 0,03777482 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,02587364 0,03993728 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,02587364 0,03990386 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,02587364 0,0398705 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,02587364 0,03983719 ! meiosis I GO:0007127 18 18 0,000 0,02587364 0,03980393 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,02587364 0,03977074 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,02587364 0,03973759 ! membrane docking GO:0022406 18 18 0,000 0,02587364 0,03970451 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,02587364 0,03967148 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,02587364 0,0396385 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,02587364 0,03960558 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,02587364 0,03957271 ! hexose transport GO:0008645 18 18 0,000 0,02587364 0,0395399 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,02587364 0,03950714 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,02587364 0,03947443 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,02587364 0,03944178 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,02587364 0,03940919 ! ceramide metabolic process GO:0006672 18 18 0,000 0,02587364 0,03937664 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,02587364 0,03934415 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,02587364 0,03931172 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,02587364 0,03927934 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,02587364 0,03924701 ! B cell differentiation GO:0030183 18 18 0,000 0,02587364 0,03921473 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,02587364 0,03918251 ! ensheathment of neurons GO:0007272 18 18 0,000 0,02587364 0,03915034 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,02587364 0,03911822 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,02587364 0,03908616 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,02587364 0,03905415 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,02587364 0,03902219 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,02587364 0,03899028 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,02729323 0,04109594 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,02729323 0,04106239 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,02729323 0,0410289 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,02729323 0,04099546 ! glial cell differentiation GO:0010001 19 19 0,000 0,02729323 0,04096208 ! regulation of pH GO:0006885 19 19 0,000 0,02729323 0,04092875 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,02729323 0,04089547 ! feeding behavior GO:0007631 19 19 0,000 0,02729323 0,04086225 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,02729323 0,04082908 ! peroxisome organization GO:0007031 19 19 0,000 0,02729323 0,04079597 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,02729323 0,04076291 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,02729323 0,0407299 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,02729323 0,04069695 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,02729323 0,04066405 ! metanephros development GO:0001656 19 19 0,000 0,02729323 0,0406312 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,02729323 0,04059841 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,02729323 0,04056567 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,02729323 0,04053298 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,02729323 0,04050034 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,02729323 0,04046776 ! peripheral nervous system development GO:0007422 19 19 0,000 0,02729323 0,04043523 ! regulation of protein stability GO:0031647 19 19 0,000 0,02729323 0,04040275 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,02729323 0,04037033 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,02729323 0,04033795 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,02729323 0,04030563 ! eye morphogenesis GO:0048592 19 19 0,000 0,02729323 0,04027336 ! regulation of cell shape GO:0008360 21 19 0,000 0,02729323 0,04024114 ! placenta development GO:0001890 19 19 0,000 0,02729323 0,04020898 ! response to heat GO:0009408 19 19 0,000 0,02729323 0,04017686 ! vesicle localization GO:0051648 20 19 0,000 0,02729323 0,0401448 ! regulation of muscle development GO:0048634 21 20 0,000 0,02871097 0,04219642 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,02871097 0,0421628 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,02871097 0,04212923 ! negative regulation of binding GO:0051100 21 20 0,000 0,02871097 0,04209571 ! organic ether metabolic process GO:0018904 20 20 0,000 0,02871097 0,04206225 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,02871097 0,04202884 ! neural tube development GO:0021915 21 20 0,000 0,02871097 0,04199548 ! nucleus organization GO:0006997 20 20 0,000 0,02871097 0,04196218 ! phagocytosis GO:0006909 21 20 0,000 0,02871097 0,04192893 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,02871097 0,04189573 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,02871097 0,04186259 ! protein targeting to membrane GO:0006612 22 20 0,000 0,02871097 0,04182949 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,02871097 0,04179645 ! chromatin remodeling GO:0006338 20 20 0,000 0,02871097 0,04176347 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,02871097 0,04173053 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,02871097 0,04169764 ! lipid oxidation GO:0034440 20 20 0,000 0,02871097 0,04166481 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,02871097 0,04163203 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,02871097 0,0415993 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,02871097 0,04156662 ! RNA modification GO:0009451 20 20 0,000 0,02871097 0,041534 ! single fertilization GO:0007338 21 20 0,000 0,02871097 0,04150142 ! regulation of B cell activation GO:0050864 20 20 0,000 0,02871097 0,0414689 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,03012684 0,04347985 ! mRNA catabolic process GO:0006402 21 21 0,000 0,03012684 0,04344583 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,03012684 0,04341186 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,03012684 0,04337794 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,03012684 0,04334408 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,03012684 0,04331027 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,03012684 0,04327651 ! Notch signaling pathway GO:0007219 22 21 0,000 0,03012684 0,04324281 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,03012684 0,04320916 ! ear morphogenesis GO:0042471 21 21 0,000 0,03012684 0,04317556 ! organic anion transport GO:0015711 21 21 0,000 0,03012684 0,04314201 ! cholesterol transport GO:0030301 21 21 0,000 0,03012684 0,04310851 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,03012684 0,04307507 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,03012684 0,04304168 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,03012684 0,04300834 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,03012684 0,04297505 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,03012684 0,04294181 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,03012684 0,04290863 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,03012684 0,04287549 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,03012684 0,04284241 ! regulation of proteolysis GO:0030162 21 21 0,000 0,03012684 0,04280938 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,03012684 0,0427764 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,03012684 0,04274347 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,03012684 0,04271059 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,03154085 0,04468086 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,03154085 0,04464654 ! sister chromatid segregation GO:0000819 22 22 0,000 0,03154085 0,04461228 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,03154085 0,04457806 ! regulation of ion transport GO:0043269 22 22 0,000 0,03154085 0,0445439 ! odontogenesis GO:0042476 22 22 0,000 0,03154085 0,0445098 ! cell junction organization GO:0034330 23 22 0,000 0,03154085 0,04447574 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,03154085 0,04444174 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,03154085 0,04440779 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,03154085 0,04437389 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,03154085 0,04434004 ! ovulation cycle process GO:0022602 22 22 0,000 0,03154085 0,04430625 ! spindle organization GO:0007051 22 22 0,000 0,03154085 0,0442725 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,03154085 0,04423881 ! cell chemotaxis GO:0060326 23 22 0,000 0,03154085 0,04420517 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,03154085 0,04417158 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,03154085 0,04413804 ! male sex differentiation GO:0046661 22 22 0,000 0,03154085 0,04410455 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,03154085 0,04407111 ! biopolymer methylation GO:0043414 22 22 0,000 0,03154085 0,04403772 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,03154085 0,04400439 ! detection of external stimulus GO:0009581 23 22 0,000 0,03154085 0,0439711 ! neuron migration GO:0001764 22 22 0,000 0,03154085 0,04393786 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,03154085 0,04390468 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,03154085 0,04387154 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,03154085 0,04383846 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,03154085 0,04380542 ! aerobic respiration GO:0009060 22 22 0,000 0,03154085 0,04377244 ! cytokine production GO:0001816 22 22 0,000 0,03154085 0,0437395 ! cytokinesis GO:0000910 23 22 0,000 0,03154085 0,04370661 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,03154085 0,04367378 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,03295301 0,0455949 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,03295301 0,04556069 ! viral infectious cycle GO:0019058 23 23 0,000 0,03295301 0,04552654 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,03295301 0,04549244 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,03295301 0,04545839 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,03295301 0,04542439 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,03295301 0,04539044 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,03295301 0,04535654 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,03295301 0,04532269 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,03295301 0,04528889 ! endocrine system development GO:0035270 23 23 0,000 0,03295301 0,04525515 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,03295301 0,04522145 ! female gonad development GO:0008585 23 23 0,000 0,03295301 0,0451878 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,03295301 0,0451542 ! lipid homeostasis GO:0055088 23 23 0,000 0,03295301 0,04512066 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,03295301 0,04508716 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,03295301 0,04505371 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,03295301 0,04502032 ! cell projection assembly GO:0030031 25 23 0,000 0,03295301 0,04498697 ! mitochondrial transport GO:0006839 24 24 0,000 0,03436332 0,04687757 ! regulation of action potential GO:0001508 24 24 0,000 0,03436332 0,0468429 ! gliogenesis GO:0042063 24 24 0,000 0,03436332 0,04680828 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,03436332 0,04677371 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,03436332 0,04673919 ! glucose homeostasis GO:0042593 24 24 0,000 0,03436332 0,04670472 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,03436332 0,0466703 ! T cell differentiation GO:0030217 24 24 0,000 0,03436332 0,04663594 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,03436332 0,04660162 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,03436332 0,04656735 ! ovulation cycle GO:0042698 24 24 0,000 0,03436332 0,04653314 ! fertilization GO:0009566 25 24 0,000 0,03436332 0,04649897 ! maintenance of protein location GO:0045185 25 24 0,000 0,03436332 0,04646486 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,03436332 0,04643079 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,03436332 0,04639678 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,03436332 0,04636281 ! glucan metabolic process GO:0044042 25 24 0,000 0,03436332 0,0463289 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,03577178 0,04819253 ! negative regulation of secretion GO:0051048 26 25 0,000 0,03577178 0,04815733 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,03577178 0,04812218 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,03577178 0,04808708 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,03577178 0,04805203 ! cellular component disassembly GO:0022411 26 25 0,000 0,03577178 0,04801703 ! endosome transport GO:0016197 25 25 0,000 0,03577178 0,04798208 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,03577178 0,04794719 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,03577178 0,04791234 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,03577178 0,04787755 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,03577178 0,0478428 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,03577178 0,04780811 ! excretion GO:0007588 25 25 0,000 0,03577178 0,04777347 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,03577178 0,04773887 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,03577178 0,04770433 ! gastrulation GO:0007369 25 25 0,000 0,03577178 0,04766984 ! heart morphogenesis GO:0003007 25 25 0,000 0,03577178 0,04763539 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,03577178 0,047601 ! regulation of endocytosis GO:0030100 25 25 0,000 0,03577178 0,04756665 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,03577178 0,04753236 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,03577178 0,04749811 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,03577178 0,04746392 ! positive regulation of binding GO:0051099 27 26 0,000 0,03717838 0,04929479 ! positive regulation of defense response GO:0031349 26 26 0,000 0,03717838 0,04925935 ! glycolysis GO:0006096 26 26 0,000 0,03717838 0,04922396 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,03717838 0,04918863 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,03717838 0,04915334 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,03717838 0,04911811 ! cellular defense response GO:0006968 26 26 0,000 0,03717838 0,04908292 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,03717838 0,04904779 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,03717838 0,0490127 ! double-strand break repair GO:0006302 27 26 0,000 0,03717838 0,04897767 ! regulation of protein secretion GO:0050708 26 26 0,000 0,03717838 0,04894268 ! germ cell development GO:0007281 27 26 0,000 0,03717838 0,04890775 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,03717838 0,04887287 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,03717838 0,04883803 ! maintenance of location in cell GO:0051651 27 26 0,000 0,03717838 0,04880325 ! synapse organization GO:0050808 26 26 0,000 0,03717838 0,04876851 ! chloride transport GO:0006821 27 27 0,000 0,03858314 0,0505752 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,03858314 0,05053925 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,03858314 0,05050336 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,03858314 0,05046751 ! learning or memory GO:0007611 28 27 0,000 0,03858314 0,05043172 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,03858314 0,05039598 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,03858314 0,05036029 ! peptide metabolic process GO:0006518 29 27 0,000 0,03858314 0,05032465 ! activation of caspase activity GO:0006919 27 27 0,000 0,03858314 0,05028906 ! mesenchymal cell development GO:0014031 29 27 0,000 0,03858314 0,05025352 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,03858314 0,05021803 ! defense response to bacterium GO:0042742 27 27 0,000 0,03858314 0,05018259 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,03858314 0,0501472 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,03858314 0,05011186 ! cell growth GO:0016049 27 27 0,000 0,03858314 0,05007657 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,03998605 0,05186087 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,03998605 0,0518244 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,03998605 0,05178798 ! carbohydrate transport GO:0008643 28 28 0,000 0,03998605 0,05175161 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,03998605 0,0517153 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,03998605 0,05167903 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,03998605 0,05164282 ! histone modification GO:0016570 28 28 0,000 0,03998605 0,05160665 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,03998605 0,05157054 ! developmental growth GO:0048589 28 28 0,000 0,03998605 0,05153447 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,03998605 0,05149846 ! cartilage development GO:0051216 29 28 0,000 0,03998605 0,0514625 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,04138713 0,05322852 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,04138713 0,0531914 ! viral reproductive process GO:0022415 29 29 0,000 0,04138713 0,05315434 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,04138713 0,05311732 ! leukocyte migration GO:0050900 30 29 0,000 0,04138713 0,05308036 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,04138713 0,05304344 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,04138713 0,05300658 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,04138713 0,05296977 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,04138713 0,05293301 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,04138713 0,0528963 ! tRNA processing GO:0008033 29 29 0,000 0,04138713 0,05285965 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,04138713 0,05282304 ! covalent chromatin modification GO:0016569 29 29 0,000 0,04138713 0,05278649 ! adult behavior GO:0030534 30 29 0,000 0,04138713 0,05274998 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,04138713 0,05271353 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,04138713 0,05267712 ! response to UV GO:0009411 29 29 0,000 0,04138713 0,05264077 ! transition metal ion transport GO:0000041 31 30 0,000 0,04278636 0,05438293 ! RNA catabolic process GO:0006401 30 30 0,000 0,04278636 0,05434545 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,04278636 0,05430803 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,04278636 0,05427065 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,04278636 0,05423332 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,04278636 0,05419605 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,04278636 0,05415883 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,04278636 0,05412166 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,04278636 0,05408454 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,04278636 0,05404747 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,04278636 0,05401045 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,04278636 0,05397348 ! response to temperature stimulus GO:0009266 30 30 0,000 0,04278636 0,05393656 ! regulation of ossification GO:0030278 30 30 0,000 0,04278636 0,05389969 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,04278636 0,05386288 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,04278636 0,05382611 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,04278636 0,0537894 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,04278636 0,05375273 ! vesicle organization GO:0016050 30 30 0,000 0,04278636 0,05371611 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,04278636 0,05367955 ! establishment of organelle localization GO:0051656 31 30 0,000 0,04278636 0,05364303 ! regulation of translational initiation GO:0006446 31 31 0,000 0,04418375 0,05535734 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,04418375 0,05531973 ! membrane fusion GO:0006944 31 31 0,000 0,04418375 0,05528218 ! B cell activation GO:0042113 31 31 0,000 0,04418375 0,05524467 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,04418375 0,05520722 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,04418375 0,05516982 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,04418375 0,05513246 ! ion transmembrane transport GO:0034220 31 31 0,000 0,04418375 0,05509516 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,04418375 0,05505791 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,04418375 0,05502071 ! digestion GO:0007586 31 31 0,000 0,04418375 0,05498356 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,04418375 0,05494646 ! regulation of DNA replication GO:0006275 32 31 0,000 0,04418375 0,0549094 ! regulation of heart contraction GO:0008016 31 31 0,000 0,04418375 0,0548724 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,04418375 0,05483545 ! camera-type eye development GO:0043010 31 31 0,000 0,04418375 0,05479855 ! extracellular matrix organization GO:0030198 31 31 0,000 0,04418375 0,0547617 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,04418375 0,0547249 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,04418375 0,05468814 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,04418375 0,05465144 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,0455793 0,05633981 ! cell redox homeostasis GO:0045454 32 32 0,000 0,0455793 0,05630205 ! muscle fiber development GO:0048747 32 32 0,000 0,0455793 0,05626434 ! glucose catabolic process GO:0006007 32 32 0,000 0,0455793 0,05622668 ! lipid modification GO:0030258 32 32 0,000 0,0455793 0,05618907 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,0455793 0,05615151 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,0455793 0,056114 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,0455793 0,05607654 ! cell maturation GO:0048469 32 32 0,000 0,0455793 0,05603913 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,0455793 0,05600177 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,0455793 0,05596446 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,0455793 0,0559272 ! kidney development GO:0001822 32 32 0,000 0,0455793 0,05588999 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,0455793 0,05585283 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,0455793 0,05581572 ! maintenance of location GO:0051235 33 32 0,000 0,0455793 0,05577866 ! negative regulation of cell size GO:0045792 33 33 0,000 0,04697303 0,05744611 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,04697303 0,05740801 ! amino acid transport GO:0006865 33 33 0,000 0,04697303 0,05736997 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,04697303 0,05733198 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,04697303 0,05729403 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,04697303 0,05725614 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,04697303 0,0572183 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,04697303 0,05718051 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,04697303 0,05714276 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,04697303 0,05710507 ! regulation of actin filament length GO:0030832 34 34 0,000 0,04836492 0,05875843 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,04836492 0,05871972 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,04836492 0,05868107 ! response to metal ion GO:0010038 34 34 0,000 0,04836492 0,05864246 ! ear development GO:0043583 34 34 0,000 0,04836492 0,0586039 ! muscle cell differentiation GO:0042692 35 34 0,000 0,04836492 0,0585654 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,04836492 0,05852695 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,04836492 0,05848854 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,04836492 0,05845019 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,04836492 0,05841189 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,04836492 0,05837363 ! secondary metabolic process GO:0019748 34 34 0,000 0,04836492 0,05833543 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,04836492 0,05829728 ! viral reproduction GO:0016032 34 34 0,000 0,04836492 0,05825918 ! detection of stimulus GO:0051606 36 34 0,000 0,04836492 0,05822112 ! acute inflammatory response GO:0002526 35 35 0,000 0,04975498 0,05985537 ! regulation of cellular component size GO:0032535 35 35 0,000 0,04975498 0,05981632 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,04975498 0,05977733 ! mesoderm development GO:0007498 35 35 0,000 0,04975498 0,05973838 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,04975498 0,05969949 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,04975498 0,05966065 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,04975498 0,05962186 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,04975498 0,05958312 ! inorganic anion transport GO:0015698 35 35 0,000 0,04975498 0,05954443 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,04975498 0,05950579 ! regulation of immune effector process GO:0002697 35 35 0,000 0,04975498 0,0594672 ! hydrogen transport GO:0006818 36 36 0,000 0,05114321 0,0610868 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,05114321 0,06104724 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,05114321 0,06100772 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,05114321 0,06096826 ! positive regulation of cell migration GO:0030335 36 36 0,000 0,05114321 0,06092885 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,05114321 0,06088949 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,05114321 0,06085018 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,05114321 0,06081092 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,05114321 0,06077172 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,05114321 0,06073256 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,05114321 0,06069345 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,05114321 0,0606544 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,05114321 0,06061539 ! gonad development GO:0008406 36 36 0,000 0,05114321 0,06057643 ! regulation of lipase activity GO:0060191 36 36 0,000 0,05114321 0,06053753 ! activation of immune response GO:0002253 36 36 0,000 0,05114321 0,06049867 ! coagulation GO:0050817 39 36 0,000 0,05114321 0,06045987 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,05252961 0,06205903 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,05252961 0,06201927 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,05252961 0,06197956 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 0,000 0,05252961 0,06193991 ! lung development GO:0030324 38 37 0,000 0,05252961 0,06190031 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,05252961 0,06186075 ! eye development GO:0001654 37 37 0,000 0,05252961 0,06182125 ! negative regulation of growth GO:0045926 37 37 0,000 0,05252961 0,0617818 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,05252961 0,0617424 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,05252961 0,06170305 ! adaptive immune response GO:0002250 37 37 0,000 0,05252961 0,06166374 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,0539142 0,0632488 ! neurotransmitter transport GO:0006836 40 38 0,000 0,0539142 0,06320857 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,0539142 0,06316838 ! exocytosis GO:0006887 40 38 0,000 0,0539142 0,06312825 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,0539142 0,06308817 ! chromosome segregation GO:0007059 38 38 0,000 0,0539142 0,06304814 ! urogenital system development GO:0001655 38 38 0,000 0,0539142 0,06300816 ! hexose catabolic process GO:0019320 38 38 0,000 0,0539142 0,06296823 ! RNA elongation GO:0006354 38 38 0,000 0,0539142 0,06292835 ! meiotic cell cycle GO:0051321 38 38 0,000 0,0539142 0,06288852 ! axon guidance GO:0007411 39 38 0,000 0,0539142 0,06284875 ! regulation of neurological system process GO:0031644 38 38 0,000 0,0539142 0,06280902 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,0539142 0,06276934 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,0539142 0,06272971 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,05529696 0,06429798 ! hemostasis GO:0007599 42 39 0,000 0,05529696 0,06425744 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,05529696 0,06421695 ! activation of MAPK activity GO:0000187 39 39 0,000 0,05529696 0,06417651 ! respiratory tube development GO:0030323 40 39 0,000 0,05529696 0,06413612 ! response to unfolded protein GO:0006986 39 39 0,000 0,05529696 0,06409578 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,05529696 0,0640555 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,05529696 0,06401526 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,05529696 0,06397508 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,05529696 0,06393494 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,05529696 0,06389486 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,05529696 0,06385482 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,05529696 0,06381484 ! respiratory system development GO:0060541 40 39 0,000 0,05529696 0,0637749 ! developmental maturation GO:0021700 39 39 0,000 0,05529696 0,06373502 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,05529696 0,06369519 ! limb development GO:0060173 39 39 0,000 0,05529696 0,0636554 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,05529696 0,06361567 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,05529696 0,06357598 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,0566779 0,06512305 ! DNA catabolic process GO:0006308 41 40 0,000 0,0566779 0,06508248 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,0566779 0,06504195 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,0566779 0,06500148 ! organelle localization GO:0051640 41 40 0,000 0,0566779 0,06496105 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,05805703 0,06650038 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,05805703 0,06645907 ! amine catabolic process GO:0009310 42 41 0,000 0,05805703 0,06641782 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,05805703 0,06637662 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,05805703 0,06633546 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,05805703 0,06629436 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,05805703 0,06625332 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,05943434 0,0677831 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,05943434 0,06774118 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,05943434 0,06769931 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,05943434 0,0676575 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,05943434 0,06761573 ! protein ubiquitination GO:0016567 43 42 0,000 0,05943434 0,06757402 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,05943434 0,06753236 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,05943434 0,06749075 ! forebrain development GO:0030900 43 42 0,000 0,05943434 0,06744919 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,05943434 0,06740768 ! reproductive structure development GO:0048608 43 43 0,000 0,06080984 0,0689253 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,06080984 0,06888293 ! alcohol catabolic process GO:0046164 43 43 0,000 0,06080984 0,06884062 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,06080984 0,06879836 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,06080984 0,06875615 ! humoral immune response GO:0006959 44 44 0,000 0,06218353 0,07026624 ! mRNA transport GO:0051028 44 44 0,000 0,06218353 0,07022318 ! protein import into nucleus GO:0006606 44 44 0,000 0,06218353 0,07018018 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,06218353 0,07013723 ! vitamin metabolic process GO:0006766 44 44 0,000 0,06218353 0,07009433 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,06218353 0,07005149 ! amine biosynthetic process GO:0009309 46 45 0,000 0,0635554 0,07155321 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,0635554 0,07150953 ! regulation of DNA binding GO:0051101 47 45 0,000 0,0635554 0,0714659 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,0635554 0,07142232 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,0635554 0,0713788 ! nuclear import GO:0051170 45 45 0,000 0,0635554 0,07133533 ! protein processing GO:0016485 45 45 0,000 0,0635554 0,07129191 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,06492548 0,07278446 ! tube morphogenesis GO:0035239 47 46 0,000 0,06492548 0,07274022 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,06492548 0,07269602 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,06492548 0,07265188 ! regulation of membrane potential GO:0042391 46 46 0,000 0,06492548 0,0726078 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,06629375 0,07409301 ! regulation of blood pressure GO:0008217 48 47 0,000 0,06629375 0,0740481 ! sex differentiation GO:0007548 47 47 0,000 0,06629375 0,07400325 ! amine transport GO:0015837 47 47 0,000 0,06629375 0,07395846 ! rhythmic process GO:0048511 47 47 0,000 0,06629375 0,07391372 ! regulation of catabolic process GO:0009894 48 47 0,000 0,06629375 0,07386903 ! calcium ion transport GO:0006816 48 48 0,000 0,06766021 0,07534608 ! actin filament organization GO:0007015 50 48 0,000 0,06766021 0,07530059 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,06766021 0,07525514 ! protein localization in nucleus GO:0034504 48 48 0,000 0,06766021 0,07520975 ! DNA recombination GO:0006310 48 48 0,000 0,06766021 0,07516442 ! leukocyte differentiation GO:0002521 50 49 0,000 0,06902488 0,07663425 ! gland development GO:0048732 51 49 0,000 0,06902488 0,07658811 ! cell cycle arrest GO:0007050 49 49 0,000 0,06902488 0,07654203 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,06902488 0,076496 ! divalent metal ion transport GO:0070838 49 49 0,000 0,06902488 0,07645003 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,06902488 0,07640411 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,06902488 0,07635825 ! response to bacterium GO:0009617 50 49 0,000 0,06902488 0,07631245 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,06902488 0,0762667 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,06902488 0,076221 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,06902488 0,07617536 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,07038775 0,07763292 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,07038775 0,07758649 ! negative regulation of transport GO:0051051 51 50 0,000 0,07038775 0,07754012 ! chromatin assembly GO:0031497 50 50 0,000 0,07038775 0,0774938 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 0,000 0,07038775 0,07744753 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,07038775 0,07740132 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,07038775 0,07735517 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,07038775 0,07730907 ! transcription initiation GO:0006352 50 50 0,000 0,07038775 0,07726302 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,07038775 0,07721703 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,07038775 0,0771711 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,07174882 0,07861657 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,07174882 0,07856986 ! positive regulation of immune response GO:0050778 51 51 0,000 0,07174882 0,0785232 ! rRNA metabolic process GO:0016072 51 51 0,000 0,07174882 0,0784766 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,07174882 0,07843005 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,07174882 0,07838356 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,07174882 0,07833713 ! protein maturation GO:0051604 51 51 0,000 0,07174882 0,07829075 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,0731081 0,07972676 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,0731081 0,07967961 ! cell fate commitment GO:0045165 52 52 0,000 0,0731081 0,07963252 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,0731081 0,07958548 ! response to light stimulus GO:0009416 53 52 0,000 0,0731081 0,0795385 ! sodium ion transport GO:0006814 53 53 0,000 0,07446558 0,08096759 ! tRNA metabolic process GO:0006399 53 53 0,000 0,07446558 0,08091985 ! response to hypoxia GO:0001666 53 53 0,000 0,07446558 0,08087217 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,07446558 0,08082454 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,07446558 0,08077697 ! regulation of T cell activation GO:0050863 53 53 0,000 0,07446558 0,08072945 ! regulation of protein transport GO:0051223 53 53 0,000 0,07446558 0,08068199 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,07582128 0,0821026 ! response to oxygen levels GO:0070482 55 54 0,000 0,07582128 0,08205439 ! response to virus GO:0009615 54 54 0,000 0,07582128 0,08200623 ! hormone metabolic process GO:0042445 55 54 0,000 0,07582128 0,08195813 ! sulfur metabolic process GO:0006790 55 54 0,000 0,07582128 0,08191009 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,07582128 0,08186211 ! nucleosome organization GO:0034728 55 55 0,000 0,07717519 0,0832751 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,07717519 0,08322637 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,07717519 0,0831777 ! in utero embryonic development GO:0001701 55 55 0,000 0,07717519 0,08312909 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,07717519 0,08308053 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,07852731 0,08448677 ! reproductive developmental process GO:0003006 56 56 0,000 0,07852731 0,08443748 ! extracellular structure organization GO:0043062 56 56 0,000 0,07852731 0,08438824 ! regulation of nervous system development GO:0051960 57 56 0,000 0,07852731 0,08433907 ! regulation of binding GO:0051098 60 57 0,000 0,07987765 0,08573938 ! ATP metabolic process GO:0046034 57 57 0,000 0,07987765 0,08568947 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,07987765 0,08563963 ! regulation of protein localization GO:0032880 58 57 0,000 0,07987765 0,08558984 ! innate immune response GO:0045087 58 58 0,000 0,08122621 0,08698426 ! dephosphorylation GO:0016311 60 59 0,000 0,08257299 0,08837516 ! carboxylic acid transport GO:0046942 59 59 0,000 0,08257299 0,08832387 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,08257299 0,08827264 ! regulation of cell development GO:0060284 60 59 0,000 0,08257299 0,08822147 ! sterol metabolic process GO:0016125 59 59 0,000 0,08257299 0,08817035 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,08257299 0,0881193 ! protein localization in organelle GO:0033365 59 59 0,000 0,08257299 0,0880683 ! immune effector process GO:0002252 59 59 0,000 0,08257299 0,08801737 ! potassium ion transport GO:0006813 60 60 0,000 0,083918 0,08939935 ! protein polymerization GO:0051258 65 60 0,000 0,083918 0,0893477 ! cellular respiration GO:0045333 62 61 0,000 0,08526123 0,09072543 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,08526123 0,09067308 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,08526123 0,09062079 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,08526123 0,09056855 ! lipid transport GO:0006869 62 62 0,000 0,08660268 0,09194052 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,08660268 0,09188759 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,08660268 0,09183472 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,08660268 0,09178191 ! protein import GO:0017038 62 62 0,000 0,08660268 0,09172916 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,08660268 0,09167648 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,08660268 0,09162385 ! regulation of secretion GO:0051046 65 63 0,000 0,08794237 0,09298783 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,08794237 0,09293451 ! glucose metabolic process GO:0006006 63 63 0,000 0,08794237 0,09288125 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,08794237 0,09282806 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,08794237 0,09277492 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,08928028 0,09413247 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,08928028 0,09407865 ! angiogenesis GO:0001525 65 64 0,000 0,08928028 0,09402489 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,08928028 0,0939712 ! anion transport GO:0006820 65 65 0,000 0,09061643 0,09532311 ! regulation of hormone levels GO:0010817 66 65 0,000 0,09061643 0,09526873 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,09195082 0,09661651 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,09195082 0,09656146 ! DNA packaging GO:0006323 66 66 0,000 0,09195082 0,09650647 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,09195082 0,09645154 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,09195082 0,09639668 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,09328344 0,09773814 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,09328344 0,0976826 ! muscle contraction GO:0006936 67 67 0,000 0,09328344 0,09762713 ! striated muscle tissue development GO:0014706 69 67 0,000 0,09328344 0,09757173 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,09328344 0,09751638 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,09328344 0,0974611 ! response to radiation GO:0009314 70 68 0,000 0,0946143 0,09879556 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,0946143 0,09873962 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,0946143 0,09868374 ! sensory perception of sound GO:0007605 71 69 0,000 0,09594341 0,10001341 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,09594341 0,09995687 ! response to nutrient levels GO:0031667 69 69 0,000 0,09594341 0,0999004 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,09594341 0,09984399 ! positive regulation of transport GO:0051050 71 70 0,000 0,09727076 0,10116817 ! cell part morphogenesis GO:0032990 75 70 0,000 0,09727076 0,10111111 ! wound healing GO:0042060 74 70 0,000 0,09727076 0,10105412 ! growth GO:0040007 70 70 0,000 0,09727076 0,10099719 ! muscle tissue development GO:0060537 72 70 0,000 0,09727076 0,10094032 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,09727076 0,10088351 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,09859635 0,10220083 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,09859635 0,10214338 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,09859635 0,102086 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 0,000 0,09859635 0,10202868 ! secretion by cell GO:0032940 75 72 0,000 0,09992019 0,10334058 ! muscle system process GO:0003012 72 72 0,000 0,09992019 0,10328262 ! sensory organ development GO:0007423 72 72 0,000 0,09992019 0,10322473 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,09992019 0,1031669 ! regulation of cytokine production GO:0001817 72 72 0,000 0,09992019 0,10310913 ! electron transport chain GO:0022900 75 74 0,000 0,10256263 0,10577668 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,10256263 0,10571752 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,10388122 0,10701682 ! response to oxidative stress GO:0006979 76 75 0,000 0,10388122 0,10695704 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,10388122 0,10689732 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,10519808 0,108192 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,10651319 0,10948344 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,10651319 0,10942241 ! microtubule-based movement GO:0007018 82 78 0,000 0,10782656 0,11070995 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,10782656 0,1106483 ! metal ion homeostasis GO:0055065 78 78 0,000 0,10782656 0,11058673 ! regulation of immune response GO:0050776 78 78 0,000 0,10782656 0,11052522 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,11044809 0,11314944 ! neuron projection development GO:0031175 85 80 0,000 0,11044809 0,11308658 ! MAPKKK cascade GO:0000165 82 81 0,000 0,11175626 0,11436246 ! tube development GO:0035295 83 81 0,000 0,11175626 0,11429899 ! lymphocyte activation GO:0046649 82 81 0,000 0,11175626 0,1142356 ! lipid catabolic process GO:0016042 82 81 0,000 0,11175626 0,11417227 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,11436739 0,11677513 ! ncRNA processing GO:0034470 83 83 0,000 0,11436739 0,11671047 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,11436739 0,11664588 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,11567037 0,11790956 ! regulation of cellular localization GO:0060341 86 85 0,000 0,11697162 0,11917009 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,11697162 0,11910425 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,11697162 0,11903848 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,11697162 0,11897279 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,11827115 0,1202282 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,11827115 0,12016192 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,11827115 0,12009572 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,11827115 0,12002958 ! heart development GO:0007507 90 87 0,000 0,11956895 0,1212799 ! male gamete generation GO:0048232 90 88 0,000 0,12086504 0,1225271 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,12086504 0,12245974 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,12086504 0,12239245 ! chemotaxis GO:0006935 90 89 0,000 0,12215941 0,12363525 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,12215941 0,12356739 ! brain development GO:0007420 91 90 0,000 0,12345206 0,12480644 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,124743 0,1260424 ! DNA replication GO:0006260 91 91 0,000 0,124743 0,12597334 ! visual perception GO:0007601 93 92 0,000 0,12603223 0,12720558 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,12603223 0,12713596 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,12603223 0,12706641 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,12603223 0,12699693 ! tissue morphogenesis GO:0048729 94 93 0,000 0,12731975 0,1282242 ! regulation of response to stress GO:0080134 97 94 0,000 0,12860556 0,12944841 ! blood vessel development GO:0001568 95 94 0,000 0,12860556 0,12937775 ! pattern specification process GO:0007389 96 94 0,000 0,12860556 0,12930717 ! cofactor metabolic process GO:0051186 95 94 0,000 0,12860556 0,12923666 ! vasculature development GO:0001944 97 96 0,000 0,13117207 0,13174393 ! endocytosis GO:0006897 99 98 0,000 0,13373177 0,13424164 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,13373177 0,13416856 ! blood circulation GO:0008015 99 98 0,000 0,13373177 0,13409557 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,13373177 0,13402265 ! muscle organ development GO:0007517 102 100 0,000 0,13628468 0,13650689 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,13628468 0,13643274 ! response to other organism GO:0051707 101 100 0,000 0,13628468 0,13635867 ! hemopoiesis GO:0030097 104 100 0,000 0,13628468 0,13628468