pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/7112-8-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 3,000 1,044E-06 3,809E-03 ! negative regulation of translation GO:0017148 31 18 2,000 1,136E-06 2,073E-03 ! positive regulation of ligase activity GO:0051351 86 70 3,000 1,246E-06 1,515E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 3,000 1,646E-06 1,501E-03 ! regulation of ligase activity GO:0051340 95 78 3,000 1,927E-06 1,406E-03 ! insulin-like growth factor I binding GO:0031994 6 5 1,000 1,316E-05 7,999E-03 ! lamin binding GO:0005521 8 5 1,000 1,316E-05 6,856E-03 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 1,000 1,316E-05 5,999E-03 GO:0010811|positive regulation of cell-substrate adhesion, ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 1,316E-05 5,333E-03 ! regulation of focal adhesion formation GO:0051893 6 6 1,000 1,972E-05 7,194E-03 ! negative regulation of protein ubiquitination GO:0031397 7 6 1,000 1,972E-05 6,54E-03 ! protein N-terminus binding GO:0047485 57 48 2,000 2,354E-05 7,157E-03 ! protein phosphorylated amino acid binding GO:0045309 9 7 1,000 2,759E-05 7,742E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 2,000 2,828E-05 7,37E-03 ! regulation of mitosis GO:0007088 79 55 2,000 3,552E-05 8,639E-03 GO:0051783|regulation of nuclear division, ! regulation of smooth muscle cell migration GO:0014910 11 8 1,000 3,676E-05 8,381E-03 ! keratinocyte proliferation GO:0043616 9 8 1,000 3,676E-05 7,888E-03 ! positive regulation of Rho GTPase activity GO:0032321 11 8 1,000 3,676E-05 7,45E-03 ! regulation of actin filament bundle formation GO:0032231 13 8 1,000 3,676E-05 7,058E-03 GO:0051492|regulation of stress fiber formation, ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 1,000 4,723E-05 8,614E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 1,000 4,723E-05 8,204E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 1,000 4,723E-05 7,831E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 2,000 5,094E-05 8,079E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 2,000 5,87E-05 8,922E-03 ! positive regulation of Ras GTPase activity GO:0032320 14 10 1,000 5,899E-05 8,608E-03 ! regulation of phosphatase activity GO:0010921 10 10 1,000 5,899E-05 8,277E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 2,000 6,719E-05 9,078E-03 ! negative regulation of caspase activity GO:0043154 12 11 1,000 7,205E-05 9,387E-03 ! positive regulation of GTPase activity GO:0043547 17 12 1,000 8,64E-05 0,01086827 ! phosphoprotein binding GO:0051219 14 12 1,000 8,64E-05 0,01050599 ! midbody GO:0030496 14 12 1,000 8,64E-05 0,01016709 ! regulation of cell cycle process GO:0010564 113 75 2,000 9,005E-05 0,01026562 ! negative regulation of peptidase activity GO:0010466 16 14 1,000 1,19E-04 0,01314992 ! positive regulation of cell growth GO:0030307 15 14 1,000 1,19E-04 0,01276316 ! release of cytochrome c from mitochondria GO:0001836 26 14 1,000 1,19E-04 0,0123985 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 1,000 1,19E-04 0,01205409 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 2,000 1,218E-04 0,01200743 GO:0010498|proteasomal protein catabolic process, ! regulation of Rho GTPase activity GO:0032319 18 15 1,000 1,372E-04 0,01316716 ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 1,000 1,566E-04 0,01465189 ! regulation of protein ubiquitination GO:0031396 27 16 1,000 1,566E-04 0,0142856 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 1,000 1,566E-04 0,01393717 ! skin development GO:0043588 20 17 1,000 1,774E-04 0,0154084 ! regulation of dephosphorylation GO:0035303 20 17 1,000 1,774E-04 0,01505006 ! positive regulation of cell size GO:0045793 19 18 1,000 1,994E-04 0,01653474 ! spindle microtubule GO:0005876 27 18 1,000 1,994E-04 0,0161673 ! chaperone binding GO:0051087 21 20 1,000 2,473E-04 0,01961264 ! nuclear inner membrane GO:0005637 21 20 1,000 2,473E-04 0,01919535 ! regulation of cell-matrix adhesion GO:0001952 26 20 1,000 2,473E-04 0,01879544 GO:0010810|regulation of cell-substrate adhesion, ! apoptotic mitochondrial changes GO:0008637 33 21 1,000 2,731E-04 0,02033547 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 1,000 3,002E-04 0,02190604 ! insulin-like growth factor binding GO:0005520 27 23 1,000 3,286E-04 0,02350515 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 1,000 3,286E-04 0,02305313 ! actin filament GO:0005884 26 24 1,000 3,582E-04 0,0246568 ! positive regulation of cell adhesion GO:0045785 34 26 1,000 4,212E-04 0,02845607 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 1,000 4,212E-04 0,02793868 ! RNA export from nucleus GO:0006405 31 27 1,000 4,546E-04 0,02961387 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 4,546E-04 0,02909433 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 1,000 5,251E-04 0,033026 ! cis-trans isomerase activity GO:0016859 32 30 1,000 5,622E-04 0,03476051 ! negative regulation of protein modification process GO:0031400 34 30 1,000 5,622E-04 0,03418117 ! negative regulation of hydrolase activity GO:0051346 36 34 1,000 7,23E-04 0,04323604 ! amino acid binding GO:0016597 40 34 1,000 7,23E-04 0,04253868 ! protein kinase inhibitor activity GO:0004860 37 34 1,000 7,23E-04 0,04186346 ! kinase inhibitor activity GO:0019210 47 35 1,000 7,662E-04 0,0436758 ! SMAD binding GO:0046332 39 36 1,000 8,107E-04 0,04550112 ! induction of apoptosis by intracellular signals GO:0008629 56 41 1,000 1,052E-03 0,05811928 ! lamellipodium GO:0030027 56 41 1,000 1,052E-03 0,05725183 ! nuclear export GO:0051168 46 42 1,000 1,103E-03 0,05918828 ! positive regulation of growth GO:0045927 47 43 1,000 1,156E-03 0,06113237 ! negative regulation of cell migration GO:0030336 53 44 1,000 1,21E-03 0,06308365 ! response to insulin stimulus GO:0032868 57 47 1,000 1,38E-03 0,07091934 ! negative regulation of cell motion GO:0051271 60 49 1,000 1,499E-03 0,07597218 ! DNA damage response, signal transduction GO:0042770 84 50 1,000 1,561E-03 0,07799814 ! keratinocyte differentiation GO:0030216 60 53 1,000 1,752E-03 0,08636989 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 1,000 1,954E-03 0,09503385 ! epidermal cell differentiation GO:0009913 66 58 1,000 2,094E-03 0,10052194 ! regulation of caspase activity GO:0043281 78 60 1,000 2,239E-03 0,10608817 ! regulation of endopeptidase activity GO:0052548 81 63 1,000 2,466E-03 0,11530984 ! negative regulation of protein kinase activity GO:0006469 78 64 1,000 2,543E-03 0,11743935 ! regulation of actin cytoskeleton organization GO:0032956 93 64 1,000 2,543E-03 0,11597136 ! negative regulation of kinase activity GO:0033673 79 65 1,000 2,622E-03 0,11809187 ! protein kinase regulator activity GO:0019887 74 66 1,000 2,702E-03 0,12021167 ! regulation of peptidase activity GO:0052547 86 67 1,000 2,783E-03 0,12233067 ! response to peptide hormone stimulus GO:0043434 79 67 1,000 2,783E-03 0,12087436 ! regulation of actin filament-based process GO:0032970 96 67 1,000 2,783E-03 0,11945231 ! amine binding GO:0043176 77 67 1,000 2,783E-03 0,11806332 ! negative regulation of transferase activity GO:0051348 85 70 1,000 3,034E-03 0,12720297 ! cell cortex GO:0005938 77 70 1,000 3,034E-03 0,12575748 ! regulation of Rho protein signal transduction GO:0035023 88 73 1,000 3,294E-03 0,13502355 ! cell leading edge GO:0031252 97 76 1,000 3,565E-03 0,14449454 ! kinase regulator activity GO:0019207 93 76 1,000 3,565E-03 0,14290669 ! regulation of Ras GTPase activity GO:0032318 88 77 1,000 3,657E-03 0,14501979 ! establishment of RNA localization GO:0051236 97 77 1,000 3,657E-03 0,14346043 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! RNA localization GO:0006403 99 79 1,000 3,846E-03 0,14924095 ! interphase of mitotic cell cycle GO:0051329 100 81 1,000 4,038E-03 0,15507045 ! ossification GO:0001503 111 82 1,000 4,136E-03 0,15717991 ! mitochondrion organization GO:0007005 104 82 1,000 4,136E-03 0,1555595 ! regulation of cell adhesion GO:0030155 98 83 1,000 4,235E-03 0,157662 ! interphase GO:0051325 103 83 1,000 4,235E-03 0,15606945 ! bone development GO:0060348 112 83 1,000 4,235E-03 0,15450876 ! growth factor binding GO:0019838 102 88 1,000 4,748E-03 0,171475 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 1,000 5,068E-03 0,18125067 ! spindle GO:0005819 126 92 1,000 5,177E-03 0,18334953 ! regulation of cellular component biogenesis GO:0044087 115 92 1,000 5,177E-03 0,18158656 ! regulation of GTPase activity GO:0043087 105 92 1,000 5,177E-03 0,17985716 ! regulation of cytoskeleton organization GO:0051493 133 93 1,000 5,287E-03 0,1819469 ! Wnt receptor signaling pathway GO:0016055 121 95 1,000 5,51E-03 0,18785871 ! carboxylic acid binding GO:0031406 108 97 1,000 5,738E-03 0,19380583 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 5,863E-03 0,19621883 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 5,863E-03 0,19443503 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 5,863E-03 0,19268336 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 5,863E-03 0,19096297 ! response to superoxide GO:0000303 5 5 0,000 5,863E-03 0,18927303 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 5,863E-03 0,18761274 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 5,863E-03 0,18598133 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 5,863E-03 0,18437804 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 5,863E-03 0,18280216 ! quinolinate metabolic process GO:0046874 5 5 0,000 5,863E-03 0,18125299 ! biotin binding GO:0009374 7 5 0,000 5,863E-03 0,17972986 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 5,863E-03 0,17823211 ! tongue development GO:0043586 6 5 0,000 5,863E-03 0,17675911 ! nose development GO:0043584 5 5 0,000 5,863E-03 0,17531027 ! cell proliferation in forebrain GO:0021846 5 5 0,000 5,863E-03 0,17388498 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 5,863E-03 0,17248268 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 5,863E-03 0,17110282 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 5,863E-03 0,16974486 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 5,863E-03 0,16840829 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 5,863E-03 0,1670926 ! glycolipid transport GO:0046836 6 5 0,000 5,863E-03 0,16579731 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 5,863E-03 0,16452195 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 5,863E-03 0,16326605 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 5,863E-03 0,16202919 ! neuron adhesion GO:0007158 5 5 0,000 5,863E-03 0,16081092 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 5,863E-03 0,15961084 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 5,863E-03 0,15842854 ! opioid peptide activity GO:0001515 6 5 0,000 5,863E-03 0,15726362 ! selenocysteine incorporation GO:0001514 5 5 0,000 5,863E-03 0,15611571 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 5,863E-03 0,15498444 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 5,863E-03 0,15386945 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 5,863E-03 0,15277038 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 5,863E-03 0,1516869 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 5,863E-03 0,15061868 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,863E-03 0,1495654 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 5,863E-03 0,14852676 ! clathrin coat assembly GO:0048268 6 5 0,000 5,863E-03 0,14750243 ! cerebral cortex cell migration GO:0021795 5 5 0,000 5,863E-03 0,14649214 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 5,863E-03 0,1454956 ! membrane hyperpolarization GO:0060081 5 5 0,000 5,863E-03 0,14451252 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 5,863E-03 0,14354264 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 5,863E-03 0,14258569 ! translation repressor activity GO:0030371 8 5 0,000 5,863E-03 0,14164141 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 5,863E-03 0,14070956 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 5,863E-03 0,13978989 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 5,863E-03 0,13888216 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 5,863E-03 0,13798615 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 5,863E-03 0,13710162 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 5,863E-03 0,13622836 ! negative regulation of heart contraction GO:0045822 5 5 0,000 5,863E-03 0,13536616 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 5,863E-03 0,1345148 ! microfibril GO:0001527 5 5 0,000 5,863E-03 0,13367408 ! troponin I binding GO:0031013 5 5 0,000 5,863E-03 0,13284381 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 5,863E-03 0,13202378 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 5,863E-03 0,13121382 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 5,863E-03 0,13041374 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 5,863E-03 0,12962335 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 5,863E-03 0,12884249 ! protein lipoylation GO:0009249 14 5 0,000 5,863E-03 0,12807098 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,863E-03 0,12730865 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 5,863E-03 0,12655534 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 5,863E-03 0,1258109 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 5,863E-03 0,12507516 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 5,863E-03 0,12434798 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 5,863E-03 0,12362921 ! glutamate catabolic process GO:0006538 6 5 0,000 5,863E-03 0,12291869 ! microvillus organization GO:0032528 5 5 0,000 5,863E-03 0,1222163 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 5,863E-03 0,12152189 ! tyrosine catabolic process GO:0006572 5 5 0,000 5,863E-03 0,12083533 ! response to pH GO:0009268 5 5 0,000 5,863E-03 0,12015648 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 5,863E-03 0,11948521 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 5,863E-03 0,1188214 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 5,863E-03 0,11816493 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,863E-03 0,11751568 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 5,863E-03 0,11687351 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,863E-03 0,11623833 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 5,863E-03 0,11561002 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 5,863E-03 0,11498846 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 5,863E-03 0,11437354 ! anaerobic glycolysis GO:0019642 5 5 0,000 5,863E-03 0,11376517 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 5,863E-03 0,11316324 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 5,863E-03 0,11256765 ! peroxisomal matrix GO:0005782 5 5 0,000 5,863E-03 0,11197829 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 5,863E-03 0,11139507 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 5,863E-03 0,11081789 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 5,863E-03 0,11024666 ! multivesicular body GO:0005771 5 5 0,000 5,863E-03 0,1096813 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 5,863E-03 0,1091217 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 5,863E-03 0,10856778 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 5,863E-03 0,10801946 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 5,863E-03 0,10747665 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 5,863E-03 0,10693926 ! epithelial cell maturation GO:0002070 14 5 0,000 5,863E-03 0,10640723 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 5,863E-03 0,10588046 ! muscle thin filament assembly GO:0030240 5 5 0,000 5,863E-03 0,10535888 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 5,863E-03 0,10484242 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 5,863E-03 0,10433099 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 0,000 5,863E-03 0,10382453 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 5,863E-03 0,10332296 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,863E-03 0,10282622 ! positive regulation of translational initiation GO:0045948 6 5 0,000 5,863E-03 0,10233422 ! nonhomologous end joining complex GO:0070419 6 5 0,000 5,863E-03 0,10184692 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 5,863E-03 0,10136423 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 5,863E-03 0,1008861 ! ATPase activator activity GO:0001671 5 5 0,000 5,863E-03 0,10041245 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 5,863E-03 0,09994324 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 0,000 5,863E-03 0,09947839 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 5,863E-03 0,09901784 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 5,863E-03 0,09856153 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 5,863E-03 0,09810942 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 5,863E-03 0,09766143 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 5,863E-03 0,09721751 ! cardiac myofibril assembly GO:0055003 5 5 0,000 5,863E-03 0,09677761 ! anterograde axon cargo transport GO:0008089 6 5 0,000 5,863E-03 0,09634168 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,863E-03 0,09590965 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 5,863E-03 0,09548149 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 5,863E-03 0,09505712 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 5,863E-03 0,09463652 ! protein localization to telomere GO:0070198 7 5 0,000 5,863E-03 0,09421962 ! response to exogenous dsRNA GO:0043330 5 5 0,000 5,863E-03 0,09380637 ! MutSalpha complex binding GO:0032407 7 5 0,000 5,863E-03 0,09339674 ! bile acid biosynthetic process GO:0006699 5 5 0,000 5,863E-03 0,09299066 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 5,863E-03 0,09258811 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 5,863E-03 0,09218902 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,863E-03 0,09179336 ! nerve growth factor binding GO:0048406 7 5 0,000 5,863E-03 0,09140108 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 5,863E-03 0,09101214 ! high-density lipoprotein binding GO:0008035 6 5 0,000 5,863E-03 0,0906265 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 5,863E-03 0,0902441 ! transcription initiation factor activity GO:0016986 5 5 0,000 5,863E-03 0,08986493 ! gas homeostasis GO:0033483 5 5 0,000 5,863E-03 0,08948892 ! Schwann cell development GO:0014044 5 5 0,000 5,863E-03 0,08911605 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 5,863E-03 0,08874628 ! cyclohydrolase activity GO:0019238 5 5 0,000 5,863E-03 0,08837956 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,863E-03 0,08801586 ! response to pheromone GO:0019236 5 5 0,000 5,863E-03 0,08765513 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 5,863E-03 0,08729736 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 5,863E-03 0,08694249 ! rhombomere development GO:0021546 6 5 0,000 5,863E-03 0,0865905 ! alanine transport GO:0032328 6 5 0,000 5,863E-03 0,08624134 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 5,863E-03 0,08589499 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 5,863E-03 0,08555141 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 5,863E-03 0,08521057 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 5,863E-03 0,08487243 ! regulation of meiosis GO:0040020 6 5 0,000 5,863E-03 0,08453697 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 5,863E-03 0,08420415 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 5,863E-03 0,08387393 ! lymphocyte costimulation GO:0031294 5 5 0,000 5,863E-03 0,0835463 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 5,863E-03 0,08322122 ! RS domain binding GO:0050733 6 5 0,000 5,863E-03 0,08289865 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 5,863E-03 0,08257858 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 5,863E-03 0,08226097 ! B cell homeostasis GO:0001782 6 5 0,000 5,863E-03 0,0819458 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 5,863E-03 0,08163303 ! anaphase GO:0051322 7 5 0,000 5,863E-03 0,08132263 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 5,863E-03 0,08101459 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 5,863E-03 0,08070888 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 5,863E-03 0,08040546 ! AP-2 adaptor complex GO:0030122 5 5 0,000 5,863E-03 0,08010432 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 5,863E-03 0,07980542 ! diuresis GO:0030146 5 5 0,000 5,863E-03 0,07950875 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 5,863E-03 0,07921427 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 5,863E-03 0,07892197 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 5,863E-03 0,07863181 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 5,863E-03 0,07834378 ! GTP-Rho binding GO:0017049 5 5 0,000 5,863E-03 0,07805786 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 5,863E-03 0,07777401 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,863E-03 0,07749222 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 5,863E-03 0,07721247 ! brown fat cell differentiation GO:0050873 5 5 0,000 5,863E-03 0,07693472 ! regulation of telomerase activity GO:0051972 6 5 0,000 5,863E-03 0,07665897 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 5,863E-03 0,07638519 ! TAP complex GO:0042825 5 5 0,000 5,863E-03 0,07611336 ! platelet dense granule GO:0042827 6 5 0,000 5,863E-03 0,07584345 ! bHLH transcription factor binding GO:0043425 5 5 0,000 5,863E-03 0,07557545 ! secretory granule organization GO:0033363 5 5 0,000 5,863E-03 0,07530934 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 5,863E-03 0,0750451 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 5,863E-03 0,0747827 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 5,863E-03 0,07452214 ! aldehyde-lyase activity GO:0016832 6 5 0,000 5,863E-03 0,07426338 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,863E-03 0,07400641 ! neural plate morphogenesis GO:0001839 6 5 0,000 5,863E-03 0,07375122 ! cyclosporin A binding GO:0016018 6 5 0,000 5,863E-03 0,07349778 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 5,863E-03 0,07324607 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 5,863E-03 0,07299608 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 5,863E-03 0,0727478 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 5,863E-03 0,0725012 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 5,863E-03 0,07225626 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 5,863E-03 0,07201297 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 5,863E-03 0,07177132 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 5,863E-03 0,07153128 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 5,863E-03 0,07129284 ! organ or tissue specific immune response GO:0002251 6 5 0,000 5,863E-03 0,07105599 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 5,863E-03 0,0708207 ! retina homeostasis GO:0001895 5 5 0,000 5,863E-03 0,07058697 ! prepulse inhibition GO:0060134 8 5 0,000 5,863E-03 0,07035478 ! maternal placenta development GO:0001893 5 5 0,000 5,863E-03 0,07012411 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 5,863E-03 0,06989494 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 5,863E-03 0,06966727 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 5,863E-03 0,06944108 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 5,863E-03 0,06921635 ! protein palmitoylation GO:0018345 5 5 0,000 5,863E-03 0,06899307 ! protein amino acid prenylation GO:0018346 6 5 0,000 5,863E-03 0,06877123 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 5,863E-03 0,06855081 ! stem cell division GO:0017145 6 5 0,000 5,863E-03 0,0683318 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 5,863E-03 0,06811418 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 5,863E-03 0,06789795 ! organ regeneration GO:0031100 6 5 0,000 5,863E-03 0,06768308 ! lymphocyte apoptosis GO:0070227 6 5 0,000 5,863E-03 0,06746957 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 5,863E-03 0,0672574 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 5,863E-03 0,06704656 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 5,863E-03 0,06683704 ! acyl carrier activity GO:0000036 5 5 0,000 5,863E-03 0,06662883 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 5,863E-03 0,0664219 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 5,863E-03 0,06621626 ! phagocytic vesicle GO:0045335 5 5 0,000 5,863E-03 0,06601189 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 5,863E-03 0,06580878 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 5,863E-03 0,06560691 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 5,863E-03 0,06540628 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 5,863E-03 0,06520687 ! polyol transport GO:0015791 8 5 0,000 5,863E-03 0,06500867 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 5,863E-03 0,06481168 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 5,863E-03 0,06461587 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 5,863E-03 0,06442124 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 5,863E-03 0,06422779 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 5,863E-03 0,06403549 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 5,863E-03 0,06384434 ! ethanol metabolic process GO:0006067 6 5 0,000 5,863E-03 0,06365432 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 5,863E-03 0,06346544 ! cobalt ion transport GO:0006824 5 5 0,000 5,863E-03 0,06327767 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 5,863E-03 0,06309101 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 5,863E-03 0,06290545 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 5,863E-03 0,06272098 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 5,863E-03 0,06253758 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 5,863E-03 0,06235526 ! sterol carrier activity GO:0005498 6 5 0,000 5,863E-03 0,06217399 ! adaptation of signaling pathway GO:0022401 6 5 0,000 5,863E-03 0,06199378 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 5,863E-03 0,0618146 ! response to acid GO:0001101 7 5 0,000 5,863E-03 0,06163646 ! fibril organization GO:0043206 5 5 0,000 5,863E-03 0,06145935 ! malate metabolic process GO:0006108 6 5 0,000 5,863E-03 0,06128325 ! regulation of dopamine uptake GO:0051584 7 5 0,000 5,863E-03 0,06110815 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 5,863E-03 0,06093405 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 5,863E-03 0,06076095 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 5,863E-03 0,06058882 ! protein maturation by protein folding GO:0022417 5 5 0,000 5,863E-03 0,06041766 ! activation of protein kinase B activity GO:0032148 15 5 0,000 5,863E-03 0,06024747 ! origin recognition complex GO:0000808 5 5 0,000 5,863E-03 0,06007824 ! neurexin binding GO:0042043 6 5 0,000 5,863E-03 0,05990995 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 5,863E-03 0,05974261 ! protein amino acid dealkylation GO:0008214 5 5 0,000 5,863E-03 0,05957619 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 5,863E-03 0,0594107 ! lipoic acid binding GO:0031405 5 5 0,000 5,863E-03 0,05924613 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 5,863E-03 0,05908247 ! lithium ion binding GO:0031403 6 5 0,000 5,863E-03 0,0589197 ! grooming behavior GO:0007625 7 5 0,000 5,863E-03 0,05875784 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 5,863E-03 0,05859686 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 5,863E-03 0,05843676 ! lymph vessel development GO:0001945 6 5 0,000 5,863E-03 0,05827753 ! bicarbonate transport GO:0015701 5 5 0,000 5,863E-03 0,05811917 ! response to interferon-gamma GO:0034341 6 5 0,000 5,863E-03 0,05796166 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 5,863E-03 0,05780501 ! endothelial cell proliferation GO:0001935 8 5 0,000 5,863E-03 0,0576492 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 5,863E-03 0,05749423 ! dorsal spinal cord development GO:0021516 6 5 0,000 5,863E-03 0,05734009 ! activation of MAPKKK activity GO:0000185 5 5 0,000 5,863E-03 0,05718677 ! synaptic vesicle maturation GO:0016188 6 5 0,000 5,863E-03 0,05703427 ! sphingoid catabolic process GO:0046521 5 5 0,000 5,863E-03 0,05688259 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 5,863E-03 0,05673171 ! neutrophil mediated immunity GO:0002446 5 5 0,000 5,863E-03 0,05658162 ! intercellular canaliculus GO:0046581 5 5 0,000 5,863E-03 0,05643233 ! dopamine binding GO:0035240 7 5 0,000 5,863E-03 0,05628382 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 5,863E-03 0,0561361 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 5,863E-03 0,05598914 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 5,863E-03 0,05584296 ! amine oxidase activity GO:0008131 7 5 0,000 5,863E-03 0,05569753 ! monocyte activation GO:0042117 9 5 0,000 5,863E-03 0,05555286 ! negative regulation of protein binding GO:0032091 5 5 0,000 5,863E-03 0,05540895 ! regulation of response to food GO:0032095 5 5 0,000 5,863E-03 0,05526577 ! response to food GO:0032094 6 5 0,000 5,863E-03 0,05512333 ! positive regulation of protein binding GO:0032092 5 5 0,000 5,863E-03 0,05498163 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 5,863E-03 0,05484065 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 5,863E-03 0,05470039 ! hedgehog receptor activity GO:0008158 5 5 0,000 5,863E-03 0,05456085 ! lipoprotein catabolic process GO:0042159 5 5 0,000 5,863E-03 0,05442202 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 5,863E-03 0,05428389 ! purine salvage GO:0043101 7 5 0,000 5,863E-03 0,05414646 ! small-subunit processome GO:0032040 5 5 0,000 5,863E-03 0,05400973 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 5,863E-03 0,05387368 ! ciliary rootlet GO:0035253 5 5 0,000 5,863E-03 0,05373832 ! myosin heavy chain binding GO:0032036 5 5 0,000 5,863E-03 0,05360364 ! nucleobase transport GO:0015851 5 5 0,000 5,863E-03 0,05346963 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 5,863E-03 0,05333629 ! GPI anchor binding GO:0034235 6 5 0,000 5,863E-03 0,05320361 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,863E-03 0,0530716 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 5,863E-03 0,05294023 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 5,863E-03 0,05280951 ! basic amino acid transport GO:0015802 5 5 0,000 5,863E-03 0,05267944 ! dendritic shaft GO:0043198 5 5 0,000 5,863E-03 0,05255001 ! terminal button GO:0043195 7 5 0,000 5,863E-03 0,05242121 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 5,863E-03 0,05229304 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 5,863E-03 0,05216549 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 5,863E-03 0,05203857 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 5,863E-03 0,05191226 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 5,863E-03 0,05178657 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 5,863E-03 0,05166148 ! response to UV-C GO:0010225 15 5 0,000 5,863E-03 0,05153699 ! positive regulation of organ growth GO:0046622 5 5 0,000 5,863E-03 0,05141311 ! response to arsenic GO:0046685 6 5 0,000 5,863E-03 0,05128982 ! IgE binding GO:0019863 5 5 0,000 5,863E-03 0,05116711 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 5,863E-03 0,05104499 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 5,863E-03 0,05092346 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 5,863E-03 0,0508025 ! response to copper ion GO:0046688 5 5 0,000 5,863E-03 0,05068212 ! response to cadmium ion GO:0046686 5 5 0,000 5,863E-03 0,0505623 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 5,863E-03 0,05044305 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 5,863E-03 0,05032436 ! protein autoprocessing GO:0016540 6 5 0,000 5,863E-03 0,05020623 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 5,863E-03 0,05008865 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 5,863E-03 0,04997162 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 5,863E-03 0,04985513 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 5,863E-03 0,04973919 ! mitotic recombination GO:0006312 15 5 0,000 5,863E-03 0,04962379 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 5,863E-03 0,04950892 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,863E-03 0,04939458 ! membrane to membrane docking GO:0022614 5 5 0,000 5,863E-03 0,04928077 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 5,863E-03 0,04916748 ! translation activator activity GO:0008494 5 5 0,000 5,863E-03 0,04905471 ! somatostatin receptor activity GO:0004994 5 5 0,000 5,863E-03 0,04894246 ! melanocortin receptor activity GO:0004977 6 5 0,000 5,863E-03 0,04883071 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 5,863E-03 0,04871948 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 5,863E-03 0,04860876 ! salivary gland morphogenesis GO:0007435 5 5 0,000 5,863E-03 0,04849853 ! galactosidase activity GO:0015925 5 5 0,000 5,863E-03 0,04838881 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 5,863E-03 0,04827958 ! cellular response to nutrient GO:0031670 5 5 0,000 5,863E-03 0,04817084 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 5,863E-03 0,04806259 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 5,863E-03 0,04795483 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 5,863E-03 0,04784755 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 5,863E-03 0,04774074 ! A band GO:0031672 5 5 0,000 5,863E-03 0,04763442 ! heat generation GO:0031649 5 5 0,000 5,863E-03 0,04752856 ! flagellum organization GO:0043064 5 5 0,000 5,863E-03 0,04742318 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 5,863E-03 0,04731826 ! disaccharide metabolic process GO:0005984 6 5 0,000 5,863E-03 0,0472138 ! glycogen catabolic process GO:0005980 16 5 0,000 5,863E-03 0,04710981 ! dopamine biosynthetic process GO:0042416 6 5 0,000 5,863E-03 0,04700627 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 5,863E-03 0,04690319 ! chromocenter GO:0010369 5 5 0,000 5,863E-03 0,04680055 ! glial cell migration GO:0008347 5 5 0,000 5,863E-03 0,04669837 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 5,863E-03 0,04659663 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 5,863E-03 0,04649533 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 5,863E-03 0,04639447 ! growth hormone receptor binding GO:0005131 5 5 0,000 5,863E-03 0,04629405 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 5,863E-03 0,04619407 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 5,863E-03 0,04609451 ! aminomethyltransferase activity GO:0004047 5 5 0,000 5,863E-03 0,04599538 ! aminoacylase activity GO:0004046 5 5 0,000 5,863E-03 0,04589668 ! penetration of zona pellucida GO:0007341 6 5 0,000 5,863E-03 0,0457984 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 5,863E-03 0,04570054 ! nucleus localization GO:0051647 5 5 0,000 5,863E-03 0,0456031 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 5,863E-03 0,04550607 ! carnitine metabolic process GO:0009437 5 5 0,000 5,863E-03 0,04540945 GO:0006577|betaine metabolic process, ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,032E-03 0,05434541 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 0,000 7,032E-03 0,05423052 ! regulation of helicase activity GO:0051095 6 6 0,000 7,032E-03 0,05411611 ! response to oxygen radical GO:0000305 6 6 0,000 7,032E-03 0,05400218 ! positive regulation of axon extension GO:0045773 7 6 0,000 7,032E-03 0,05388873 ! forebrain neuron differentiation GO:0021879 6 6 0,000 7,032E-03 0,05377576 ! forebrain regionalization GO:0021871 7 6 0,000 7,032E-03 0,05366325 ! meiotic prophase I GO:0007128 7 6 0,000 7,032E-03 0,05355122 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 7,032E-03 0,05343966 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 7,032E-03 0,05332856 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 7,032E-03 0,05321792 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 7,032E-03 0,05310773 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 7,032E-03 0,05299801 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 7,032E-03 0,05288873 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 7,032E-03 0,05277991 ! protein amino acid sulfation GO:0006477 9 6 0,000 7,032E-03 0,05267153 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 7,032E-03 0,0525636 ! establishment of tissue polarity GO:0007164 8 6 0,000 7,032E-03 0,05245611 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 7,032E-03 0,05234905 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 7,032E-03 0,05224244 ! embryonic camera-type eye development GO:0031076 9 6 0,000 7,032E-03 0,05213625 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 7,032E-03 0,0520305 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 7,032E-03 0,05192517 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 7,032E-03 0,05182027 ! Notch receptor processing GO:0007220 7 6 0,000 7,032E-03 0,0517158 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 7,032E-03 0,05161174 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 7,032E-03 0,0515081 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 7,032E-03 0,05140488 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 7,032E-03 0,05130207 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 7,032E-03 0,05119967 ! neurofilament GO:0005883 7 6 0,000 7,032E-03 0,05109768 ! glial cell fate commitment GO:0021781 7 6 0,000 7,032E-03 0,05099609 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 7,032E-03 0,05089491 ! dynactin complex GO:0005869 7 6 0,000 7,032E-03 0,05079413 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 7,032E-03 0,05069375 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 7,032E-03 0,05059376 ! oocyte maturation GO:0001556 6 6 0,000 7,032E-03 0,05049416 ! DNA replication origin binding GO:0003688 6 6 0,000 7,032E-03 0,05039496 ! reflex GO:0060004 10 6 0,000 7,032E-03 0,05029615 ! positive regulation of glycolysis GO:0045821 6 6 0,000 7,032E-03 0,05019772 ! parathyroid gland development GO:0060017 6 6 0,000 7,032E-03 0,05009968 ! anagen GO:0042640 7 6 0,000 7,032E-03 0,05000202 ! protein-cofactor linkage GO:0018065 15 6 0,000 7,032E-03 0,04990474 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 7,032E-03 0,04980784 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 7,032E-03 0,04971131 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 7,032E-03 0,04961516 ! skeletal myofibril assembly GO:0014866 6 6 0,000 7,032E-03 0,04951937 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 7,032E-03 0,04942396 ! cysteine metabolic process GO:0006534 7 6 0,000 7,032E-03 0,04932891 ! glycine catabolic process GO:0006546 6 6 0,000 7,032E-03 0,04923423 ! adenohypophysis development GO:0021984 6 6 0,000 7,032E-03 0,04913992 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 7,032E-03 0,04904596 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 7,032E-03 0,04895236 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 7,032E-03 0,04885912 ! microtubule nucleation GO:0007020 7 6 0,000 7,032E-03 0,04876623 ! proline biosynthetic process GO:0006561 8 6 0,000 7,032E-03 0,04867369 ! tryptophan metabolic process GO:0006568 6 6 0,000 7,032E-03 0,04858151 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 7,032E-03 0,04848967 ! thyroid hormone generation GO:0006590 6 6 0,000 7,032E-03 0,04839818 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 7,032E-03 0,04830704 ! retinoid X receptor binding GO:0046965 7 6 0,000 7,032E-03 0,04821623 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 7,032E-03 0,04812577 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 7,032E-03 0,04803565 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 7,032E-03 0,04794586 ! sister chromatid cohesion GO:0007062 6 6 0,000 7,032E-03 0,04785641 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 7,032E-03 0,04776729 ! positive regulation of transporter activity GO:0032411 8 6 0,000 7,032E-03 0,04767851 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 7,032E-03 0,04759005 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 7,032E-03 0,04750192 ! p53 binding GO:0002039 6 6 0,000 7,032E-03 0,04741411 ! demethylase activity GO:0032451 6 6 0,000 7,032E-03 0,04732663 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 7,032E-03 0,04723948 ! regulation of platelet activation GO:0010543 7 6 0,000 7,032E-03 0,04715264 ! lipid phosphatase activity GO:0042577 7 6 0,000 7,032E-03 0,04706612 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 7,032E-03 0,04697992 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 7,032E-03 0,04689403 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 7,032E-03 0,04680846 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 7,032E-03 0,0467232 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 7,032E-03 0,04663825 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 7,032E-03 0,0465536 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 7,032E-03 0,04646927 ! LIM domain binding GO:0030274 7 6 0,000 7,032E-03 0,04638524 ! negative regulation of translational initiation GO:0045947 6 6 0,000 7,032E-03 0,04630151 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 7,032E-03 0,04621808 ! 5S class rRNA transcription GO:0042791 6 6 0,000 7,032E-03 0,04613496 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 7,032E-03 0,04605213 ! axon guidance receptor activity GO:0008046 6 6 0,000 7,032E-03 0,0459696 ! zinc ion homeostasis GO:0055069 7 6 0,000 7,032E-03 0,04588736 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 7,032E-03 0,04580542 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 7,032E-03 0,04572377 ! protein targeting to lysosome GO:0006622 6 6 0,000 7,032E-03 0,04564241 ! hyaluronan metabolic process GO:0030212 8 6 0,000 7,032E-03 0,04556134 ! protein retention in ER lumen GO:0006621 6 6 0,000 7,032E-03 0,04548056 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 7,032E-03 0,04540006 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 7,032E-03 0,04531985 ! dynein binding GO:0045502 6 6 0,000 7,032E-03 0,04523992 ! regulation of dendrite development GO:0050773 6 6 0,000 7,032E-03 0,04516027 ! peptidyl-arginine modification GO:0018195 6 6 0,000 7,032E-03 0,04508091 ! eating behavior GO:0042755 7 6 0,000 7,032E-03 0,04500182 ! protein localization to chromosome GO:0034502 8 6 0,000 7,032E-03 0,044923 ! Hsp90 protein binding GO:0051879 7 6 0,000 7,032E-03 0,04484447 ! glycolipid binding GO:0051861 7 6 0,000 7,032E-03 0,04476621 ! MutLalpha complex binding GO:0032405 8 6 0,000 7,032E-03 0,04468822 ! mast cell activation GO:0045576 6 6 0,000 7,032E-03 0,0446105 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,032E-03 0,04453305 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 7,032E-03 0,04445587 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 7,032E-03 0,04437895 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 7,032E-03 0,04430231 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 7,032E-03 0,04422592 ! lipoxygenase activity GO:0016165 6 6 0,000 7,032E-03 0,0441498 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 7,032E-03 0,04407394 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 7,032E-03 0,04399835 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 7,032E-03 0,04392301 ! DNA replication factor C complex GO:0005663 7 6 0,000 7,032E-03 0,04384792 ! DNA replication factor A complex GO:0005662 7 6 0,000 7,032E-03 0,0437731 ! establishment of chromosome localization GO:0051303 15 6 0,000 7,032E-03 0,04369853 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 7,032E-03 0,04362421 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 7,032E-03 0,04355015 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 7,032E-03 0,04347633 ! chromatin assembly complex GO:0005678 16 6 0,000 7,032E-03 0,04340277 ! sex chromatin GO:0001739 6 6 0,000 7,032E-03 0,04332945 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 7,032E-03 0,04325638 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 7,032E-03 0,04318356 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 7,032E-03 0,04311098 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 7,032E-03 0,04303865 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 7,032E-03 0,04296656 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 7,032E-03 0,04289471 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 7,032E-03 0,0428231 ! phosphatidylserine binding GO:0001786 6 6 0,000 7,032E-03 0,04275173 ! alpha-mannosidase activity GO:0004559 8 6 0,000 7,032E-03 0,04268059 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 7,032E-03 0,04260969 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 7,032E-03 0,04253903 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 7,032E-03 0,0424686 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 7,032E-03 0,04239841 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 7,032E-03 0,04232844 ! leading edge membrane GO:0031256 8 6 0,000 7,032E-03 0,04225871 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 7,032E-03 0,0421892 ! CARD domain binding GO:0050700 6 6 0,000 7,032E-03 0,04211993 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 7,032E-03 0,04205088 ! COPII vesicle coat GO:0030127 7 6 0,000 7,032E-03 0,04198206 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 7,032E-03 0,04191346 ! glutathione biosynthetic process GO:0006750 7 6 0,000 7,032E-03 0,04184508 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 7,032E-03 0,04177693 ! positive regulation of epidermis development GO:0045684 8 6 0,000 7,032E-03 0,041709 ! proteasome regulator activity GO:0010860 6 6 0,000 7,032E-03 0,04164129 ! ceramidase activity GO:0017040 6 6 0,000 7,032E-03 0,0415738 ! antibiotic transport GO:0042891 7 6 0,000 7,032E-03 0,04150653 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 7,032E-03 0,04143948 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 7,032E-03 0,04137264 ! sodium channel regulator activity GO:0017080 6 6 0,000 7,032E-03 0,04130602 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,032E-03 0,04123961 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 7,032E-03 0,04117341 ! response to fluid shear stress GO:0034405 6 6 0,000 7,032E-03 0,04110743 ! lymph node development GO:0048535 6 6 0,000 7,032E-03 0,04104166 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 7,032E-03 0,0409761 ! triglyceride catabolic process GO:0019433 15 6 0,000 7,032E-03 0,04091074 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 7,032E-03 0,0408456 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 7,032E-03 0,04078066 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 7,032E-03 0,04071593 ! negative regulation of lipase activity GO:0060192 6 6 0,000 7,032E-03 0,0406514 ! activation of innate immune response GO:0002218 6 6 0,000 7,032E-03 0,04058708 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 7,032E-03 0,04052296 ! sarcoglycan complex GO:0016012 8 6 0,000 7,032E-03 0,04045905 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 7,032E-03 0,04039533 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 7,032E-03 0,04033182 ! neural plate development GO:0001840 7 6 0,000 7,032E-03 0,0402685 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 7,032E-03 0,04020539 ! catecholamine transport GO:0051937 6 6 0,000 7,032E-03 0,04014247 ! ether hydrolase activity GO:0016803 7 6 0,000 7,032E-03 0,04007974 ! FACIT collagen GO:0005593 6 6 0,000 7,032E-03 0,04001722 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 7,032E-03 0,03995488 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 7,032E-03 0,03989275 ! collagen type IV GO:0005587 6 6 0,000 7,032E-03 0,0398308 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 7,032E-03 0,03976905 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 7,032E-03 0,03970749 ! drug metabolic process GO:0017144 6 6 0,000 7,032E-03 0,03964611 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 7,032E-03 0,03958493 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 7,032E-03 0,03952394 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 7,032E-03 0,03946313 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 7,032E-03 0,03940251 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 7,032E-03 0,03934208 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 7,032E-03 0,03928183 ! cellular anion homeostasis GO:0030002 6 6 0,000 7,032E-03 0,03922177 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 7,032E-03 0,03916189 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 7,032E-03 0,03910219 ! behavioral response to cocaine GO:0048148 9 6 0,000 7,032E-03 0,03904267 ! translation initiation factor binding GO:0031369 6 6 0,000 7,032E-03 0,03898334 ! nucleotide-sugar transport GO:0015780 6 6 0,000 7,032E-03 0,03892418 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 7,032E-03 0,03886521 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 7,032E-03 0,03880641 ! quaternary ammonium group binding GO:0050997 7 6 0,000 7,032E-03 0,03874779 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 7,032E-03 0,03868934 ! reproductive behavior GO:0019098 8 6 0,000 7,032E-03 0,03863108 ! response to growth hormone stimulus GO:0060416 7 6 0,000 7,032E-03 0,03857299 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 7,032E-03 0,03851507 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 7,032E-03 0,03845732 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 7,032E-03 0,03839975 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 7,032E-03 0,03834236 ! induction of positive chemotaxis GO:0050930 7 6 0,000 7,032E-03 0,03828513 ! cohesin complex GO:0008278 6 6 0,000 7,032E-03 0,03822807 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 7,032E-03 0,03817118 ! citrate metabolic process GO:0006101 7 6 0,000 7,032E-03 0,03811447 ! myelin sheath GO:0043209 8 6 0,000 7,032E-03 0,03805792 ! phototransduction, visible light GO:0007603 6 6 0,000 7,032E-03 0,03800153 ! opsonization GO:0008228 7 6 0,000 7,032E-03 0,03794532 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 7,032E-03 0,03788927 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 7,032E-03 0,03783339 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 7,032E-03 0,03777767 ! regulation of potassium ion transport GO:0043266 8 6 0,000 7,032E-03 0,03772211 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 7,032E-03 0,03766672 ! chemoattractant activity GO:0042056 6 6 0,000 7,032E-03 0,03761149 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 7,032E-03 0,03755642 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 7,032E-03 0,03750151 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 7,032E-03 0,03744677 ! leukocyte degranulation GO:0043299 6 6 0,000 7,032E-03 0,03739218 ! bile acid and bile salt transport GO:0015721 7 6 0,000 7,032E-03 0,03733775 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 7,032E-03 0,03728348 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 7,032E-03 0,03722937 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 7,032E-03 0,03717541 ! DNA topoisomerase activity GO:0003916 6 6 0,000 7,032E-03 0,03712161 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 7,032E-03 0,03706797 ! ceramide biosynthetic process GO:0046513 6 6 0,000 7,032E-03 0,03701448 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 7,032E-03 0,03696115 ! activin receptor activity GO:0017002 7 6 0,000 7,032E-03 0,03690797 ! astrocyte differentiation GO:0048708 6 6 0,000 7,032E-03 0,03685494 ! syncytium formation GO:0006949 6 6 0,000 7,032E-03 0,03680206 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 7,032E-03 0,03674933 ! neutrophil activation GO:0042119 6 6 0,000 7,032E-03 0,03669676 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 7,032E-03 0,03664434 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 7,032E-03 0,03659206 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 7,032E-03 0,03653994 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 7,032E-03 0,03648796 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 7,032E-03 0,03643613 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 7,032E-03 0,03638445 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 7,032E-03 0,03633291 ! neuron apoptosis GO:0051402 7 6 0,000 7,032E-03 0,03628152 ! folic acid transport GO:0015884 8 6 0,000 7,032E-03 0,03623028 ! carnitine transport GO:0015879 6 6 0,000 7,032E-03 0,03617918 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 7,032E-03 0,03612822 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 7,032E-03 0,03607741 ! S-methyltransferase activity GO:0008172 6 6 0,000 7,032E-03 0,03602674 ! phospholipase D activity GO:0004630 6 6 0,000 7,032E-03 0,03597621 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 7,032E-03 0,03592582 ! intercalated disc GO:0014704 8 6 0,000 7,032E-03 0,03587557 ! G2/M transition checkpoint GO:0031576 24 6 0,000 7,032E-03 0,03582547 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 7,032E-03 0,0357755 ! IgG binding GO:0019864 6 6 0,000 7,032E-03 0,03572568 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 7,032E-03 0,03567599 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 7,032E-03 0,03562644 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 7,032E-03 0,03557703 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 7,032E-03 0,03552775 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 7,032E-03 0,03547861 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 7,032E-03 0,03542961 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 7,032E-03 0,03538074 ! dendrite morphogenesis GO:0048813 7 6 0,000 7,032E-03 0,03533201 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 7,032E-03 0,03528341 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 7,032E-03 0,03523494 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 7,032E-03 0,03518661 ! nucleosome disassembly GO:0006337 7 6 0,000 7,032E-03 0,03513841 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 7,032E-03 0,03509034 ! regulation of mast cell activation GO:0033003 6 6 0,000 7,032E-03 0,0350424 ! tetracycline transporter activity GO:0008493 7 6 0,000 7,032E-03 0,03499459 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 7,032E-03 0,03494692 ! receptor internalization GO:0031623 8 6 0,000 7,032E-03 0,03489937 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 7,032E-03 0,03485195 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 7,032E-03 0,03480466 ! histamine receptor activity GO:0004969 7 6 0,000 7,032E-03 0,0347575 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 7,032E-03 0,03471047 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 7,032E-03 0,03466356 ! protein deubiquitination GO:0016579 6 6 0,000 7,032E-03 0,03461678 ! axonal fasciculation GO:0007413 7 6 0,000 7,032E-03 0,03457013 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 7,032E-03 0,0345236 ! cytidine deaminase activity GO:0004126 6 6 0,000 7,032E-03 0,0344772 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 7,032E-03 0,03443092 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 7,032E-03 0,03438477 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 7,032E-03 0,03433874 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 7,032E-03 0,03429283 ! glycine binding GO:0016594 9 6 0,000 7,032E-03 0,03424704 ! apical protein localization GO:0045176 7 6 0,000 7,032E-03 0,03420138 ! ankyrin binding GO:0030506 6 6 0,000 7,032E-03 0,03415584 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 7,032E-03 0,03411042 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 7,032E-03 0,03406512 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 7,032E-03 0,03401994 ! progesterone metabolic process GO:0042448 6 6 0,000 7,032E-03 0,03397488 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 7,032E-03 0,03392994 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 7,032E-03 0,03388512 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 7,032E-03 0,03384042 ! ATP catabolic process GO:0006200 6 6 0,000 7,032E-03 0,03379583 ! CoA carboxylase activity GO:0016421 6 6 0,000 7,032E-03 0,03375136 ! determination of adult lifespan GO:0008340 6 6 0,000 7,032E-03 0,03370701 ! S-acyltransferase activity GO:0016417 6 6 0,000 7,032E-03 0,03366278 ! somatic stem cell maintenance GO:0035019 6 6 0,000 7,032E-03 0,03361866 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 7,032E-03 0,03357465 ! IkappaB kinase complex GO:0008385 7 6 0,000 7,032E-03 0,03353077 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 7,032E-03 0,03348699 ! store-operated calcium channel activity GO:0015279 6 6 0,000 7,032E-03 0,03344333 ! alkaline phosphatase activity GO:0004035 7 6 0,000 7,032E-03 0,03339979 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 7,032E-03 0,03335635 ! unconventional myosin complex GO:0016461 8 6 0,000 7,032E-03 0,03331303 ! tRNA transcription GO:0009304 7 7 0,000 8,199E-03 0,03879304 ! respiratory burst GO:0045730 7 7 0,000 8,199E-03 0,03874279 ! telencephalon cell migration GO:0022029 8 7 0,000 8,199E-03 0,03869267 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 8,199E-03 0,03864268 ! cation:chloride symporter activity GO:0015377 8 7 0,000 8,199E-03 0,03859282 ! RNA cap binding GO:0000339 8 7 0,000 8,199E-03 0,03854309 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 8,199E-03 0,03849348 ! ephrin receptor binding GO:0046875 9 7 0,000 8,199E-03 0,038444 ! male meiosis I GO:0007141 7 7 0,000 8,199E-03 0,03839465 ! synapsis GO:0007129 7 7 0,000 8,199E-03 0,03834543 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 8,199E-03 0,03829633 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 8,199E-03 0,03824736 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 8,199E-03 0,03819851 ! signal peptide processing GO:0006465 7 7 0,000 8,199E-03 0,03814979 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 8,199E-03 0,03810119 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 8,199E-03 0,03805272 ! macrophage chemotaxis GO:0048246 7 7 0,000 8,199E-03 0,03800436 ! Golgi cisterna membrane GO:0032580 7 7 0,000 8,199E-03 0,03795614 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 8,199E-03 0,03790803 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 8,199E-03 0,03786004 ! smoothened signaling pathway GO:0007224 8 7 0,000 8,199E-03 0,03781218 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 8,199E-03 0,03776444 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 8,199E-03 0,03771682 ! cytoplasmic microtubule GO:0005881 7 7 0,000 8,199E-03 0,03766931 ! Arp2/3 protein complex GO:0005885 8 7 0,000 8,199E-03 0,03762193 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 8,199E-03 0,03757467 ! ATPase binding GO:0051117 8 7 0,000 8,199E-03 0,03752752 ! positive regulation of isotype switching GO:0045830 7 7 0,000 8,199E-03 0,03748049 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 8,199E-03 0,03743359 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 8,199E-03 0,03738679 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 8,199E-03 0,03734012 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,199E-03 0,03729356 ! thymic T cell selection GO:0045061 16 7 0,000 8,199E-03 0,03724712 ! transepithelial chloride transport GO:0030321 7 7 0,000 8,199E-03 0,03720079 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 8,199E-03 0,03715458 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 8,199E-03 0,03710848 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 8,199E-03 0,0370625 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 8,199E-03 0,03701663 ! melanocyte differentiation GO:0030318 8 7 0,000 8,199E-03 0,03697087 ! malate dehydrogenase activity GO:0016615 8 7 0,000 8,199E-03 0,03692523 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 8,199E-03 0,0368797 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 8,199E-03 0,03683428 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 8,199E-03 0,03678897 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 8,199E-03 0,03674378 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 8,199E-03 0,03669869 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 8,199E-03 0,03665372 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 8,199E-03 0,03660886 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 8,199E-03 0,0365641 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 8,199E-03 0,03651946 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 8,199E-03 0,03647492 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 8,199E-03 0,03643049 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 8,199E-03 0,03638617 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 8,199E-03 0,03634196 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 8,199E-03 0,03629786 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 8,199E-03 0,03625386 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 8,199E-03 0,03620997 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 8,199E-03 0,03616618 ! melanosome organization GO:0032438 7 7 0,000 8,199E-03 0,03612251 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 8,199E-03 0,03607893 ! mesodermal cell differentiation GO:0048333 9 7 0,000 8,199E-03 0,03603546 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 8,199E-03 0,0359921 ! Rac protein signal transduction GO:0016601 7 7 0,000 8,199E-03 0,03594884 ! chondrocyte differentiation GO:0002062 7 7 0,000 8,199E-03 0,03590568 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 8,199E-03 0,03586263 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 8,199E-03 0,03581968 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 8,199E-03 0,03577684 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 8,199E-03 0,03573409 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 8,199E-03 0,03569145 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 8,199E-03 0,03564891 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 8,199E-03 0,03560647 ! Schwann cell differentiation GO:0014037 8 7 0,000 8,199E-03 0,03556413 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 8,199E-03 0,03552189 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 8,199E-03 0,03547976 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 8,199E-03 0,03543772 ! vinculin binding GO:0017166 9 7 0,000 8,199E-03 0,03539578 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 8,199E-03 0,03535394 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 8,199E-03 0,0353122 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 8,199E-03 0,03527056 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 8,199E-03 0,03522902 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 8,199E-03 0,03518757 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 8,199E-03 0,03514622 ! cardiac muscle cell development GO:0055013 8 7 0,000 8,199E-03 0,03510497 ! fibrinolysis GO:0042730 9 7 0,000 8,199E-03 0,03506382 ! response to tropane GO:0014073 10 7 0,000 8,199E-03 0,03502276 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 8,199E-03 0,03498179 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 8,199E-03 0,03494093 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 8,199E-03 0,03490016 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 8,199E-03 0,03485948 ! laminin-1 complex GO:0005606 7 7 0,000 8,199E-03 0,0348189 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 8,199E-03 0,03477841 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 8,199E-03 0,03473802 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 8,199E-03 0,03469772 ! regulation of cell division GO:0051302 7 7 0,000 8,199E-03 0,03465751 ! holo TFIIH complex GO:0005675 7 7 0,000 8,199E-03 0,0346174 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 8,199E-03 0,03457738 ! chitinase activity GO:0004568 7 7 0,000 8,199E-03 0,03453745 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 8,199E-03 0,03449762 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 8,199E-03 0,03445787 ! regulation of respiratory burst GO:0060263 8 7 0,000 8,199E-03 0,03441822 ! prophase GO:0051324 8 7 0,000 8,199E-03 0,03437866 ! peptidyl-histidine modification GO:0018202 8 7 0,000 8,199E-03 0,03433919 ! centriolar satellite GO:0034451 10 7 0,000 8,199E-03 0,03429981 ! BBSome GO:0034464 7 7 0,000 8,199E-03 0,03426052 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 8,199E-03 0,03422132 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 8,199E-03 0,03418221 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 8,199E-03 0,03414319 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 8,199E-03 0,03410426 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 8,199E-03 0,03406542 ! regulation of synaptogenesis GO:0051963 7 7 0,000 8,199E-03 0,03402666 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 8,199E-03 0,03398799 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 8,199E-03 0,03394942 ! glycolipid catabolic process GO:0019377 7 7 0,000 8,199E-03 0,03391092 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 8,199E-03 0,03387252 ! circadian behavior GO:0048512 9 7 0,000 8,199E-03 0,0338342 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 8,199E-03 0,03379597 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 8,199E-03 0,03375783 ! striatum development GO:0021756 7 7 0,000 8,199E-03 0,03371977 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 8,199E-03 0,0336818 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 8,199E-03 0,03364391 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 8,199E-03 0,03360611 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 8,199E-03 0,03356839 ! dystroglycan complex GO:0016011 9 7 0,000 8,199E-03 0,03353076 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 8,199E-03 0,03349321 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 8,199E-03 0,03345574 ! peroxiredoxin activity GO:0051920 7 7 0,000 8,199E-03 0,03341836 ! muscle adaptation GO:0043500 7 7 0,000 8,199E-03 0,03338107 ! regulation of muscle adaptation GO:0043502 7 7 0,000 8,199E-03 0,03334385 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 8,199E-03 0,03330672 ! lysogeny GO:0030069 7 7 0,000 8,199E-03 0,03326967 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 8,199E-03 0,03323271 ! sequestering of metal ion GO:0051238 9 7 0,000 8,199E-03 0,03319582 ! membrane attack complex GO:0005579 7 7 0,000 8,199E-03 0,03315902 ! fibrinogen complex GO:0005577 7 7 0,000 8,199E-03 0,0331223 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 8,199E-03 0,03308566 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 8,199E-03 0,0330491 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 8,199E-03 0,03301262 ! GABA receptor binding GO:0050811 8 7 0,000 8,199E-03 0,03297622 ! sheet-forming collagen GO:0030935 7 7 0,000 8,199E-03 0,03293991 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 8,199E-03 0,03290367 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 8,199E-03 0,03286751 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 8,199E-03 0,03283143 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 8,199E-03 0,03279543 ! 7S RNA binding GO:0008312 8 7 0,000 8,199E-03 0,03275951 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 8,199E-03 0,03272367 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 8,199E-03 0,03268791 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 8,199E-03 0,03265222 ! Golgi to endosome transport GO:0006895 8 7 0,000 8,199E-03 0,03261661 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 8,199E-03 0,03258108 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 8,199E-03 0,03254563 ! fibril GO:0043205 7 7 0,000 8,199E-03 0,03251026 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 8,199E-03 0,03247496 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 8,199E-03 0,03243973 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 8,199E-03 0,03240459 ! sensory perception of bitter taste GO:0050913 7 7 0,000 8,199E-03 0,03236952 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 8,199E-03 0,03233452 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 8,199E-03 0,03229961 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 8,199E-03 0,03226476 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 8,199E-03 0,03222999 ! equilibrioception GO:0050957 10 7 0,000 8,199E-03 0,0321953 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 8,199E-03 0,03216068 ! titin binding GO:0031432 7 7 0,000 8,199E-03 0,03212614 ! chemosensory behavior GO:0007635 9 7 0,000 8,199E-03 0,03209167 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 8,199E-03 0,03205727 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 8,199E-03 0,03202295 ! cobalamin binding GO:0031419 7 7 0,000 8,199E-03 0,0319887 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 8,199E-03 0,03195452 ! response to axon injury GO:0048678 9 7 0,000 8,199E-03 0,03192042 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 8,199E-03 0,03188639 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 8,199E-03 0,03185243 ! F-actin capping protein complex GO:0008290 8 7 0,000 8,199E-03 0,03181855 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 8,199E-03 0,03178473 ! cGMP-mediated signaling GO:0019934 8 7 0,000 8,199E-03 0,03175099 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 8,199E-03 0,03171732 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 8,199E-03 0,03168372 ! senescence GO:0010149 8 7 0,000 8,199E-03 0,0316502 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 8,199E-03 0,03161674 ! nuclear localization sequence binding GO:0008139 8 7 0,000 8,199E-03 0,03158335 ! galactose metabolic process GO:0006012 8 7 0,000 8,199E-03 0,03155004 ! vesicle fusion GO:0006906 8 7 0,000 8,199E-03 0,03151679 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 8,199E-03 0,03148362 ! intracellular pH reduction GO:0051452 7 7 0,000 8,199E-03 0,03145051 ! glycerol ether catabolic process GO:0044269 16 7 0,000 8,199E-03 0,03141747 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 8,199E-03 0,03138451 ! ruffle organization GO:0031529 9 7 0,000 8,199E-03 0,03135161 ! nucleoside transport GO:0015858 8 7 0,000 8,199E-03 0,03131878 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 8,199E-03 0,03128602 ! inclusion body GO:0016234 7 7 0,000 8,199E-03 0,03125333 ! Cajal body GO:0015030 7 7 0,000 8,199E-03 0,0312207 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 8,199E-03 0,03118815 ! rRNA modification GO:0000154 7 7 0,000 8,199E-03 0,03115566 ! PcG protein complex GO:0031519 7 7 0,000 8,199E-03 0,03112324 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 8,199E-03 0,03109089 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 8,199E-03 0,0310586 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 8,199E-03 0,03102638 ! apolipoprotein binding GO:0034185 9 7 0,000 8,199E-03 0,03099423 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 8,199E-03 0,03096215 ! segment specification GO:0007379 9 7 0,000 8,199E-03 0,03093013 ! pronucleus GO:0045120 25 7 0,000 8,199E-03 0,03089818 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 8,199E-03 0,03086629 ! Rac GTPase activator activity GO:0030675 9 7 0,000 8,199E-03 0,03083447 ! regulation of DNA repair GO:0006282 19 7 0,000 8,199E-03 0,03080271 ! preribosome GO:0030684 7 7 0,000 8,199E-03 0,03077102 ! DNA topological change GO:0006265 7 7 0,000 8,199E-03 0,0307394 ! DNA ligation GO:0006266 8 7 0,000 8,199E-03 0,03070784 ! hair follicle maturation GO:0048820 8 7 0,000 8,199E-03 0,03067634 ! renal water homeostasis GO:0003091 7 7 0,000 8,199E-03 0,03064491 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 8,199E-03 0,03061355 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 8,199E-03 0,03058224 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 8,199E-03 0,03055101 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 8,199E-03 0,03051983 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 8,199E-03 0,03048872 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 8,199E-03 0,03045767 ! phosphofructokinase activity GO:0008443 7 7 0,000 8,199E-03 0,03042669 ! gap junction channel activity GO:0005243 8 7 0,000 8,199E-03 0,03039577 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 8,199E-03 0,03036491 ! histone methylation GO:0016571 7 7 0,000 8,199E-03 0,03033411 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 8,199E-03 0,03030338 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 8,199E-03 0,03027271 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 8,199E-03 0,0302421 ! muscle cell proliferation GO:0033002 8 7 0,000 8,199E-03 0,03021155 ! transcription termination GO:0006353 9 7 0,000 8,199E-03 0,03018106 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 0,000 8,199E-03 0,03015064 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 8,199E-03 0,03012028 ! cytidylyltransferase activity GO:0070567 8 7 0,000 8,199E-03 0,03008997 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 8,199E-03 0,03005973 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 8,199E-03 0,03002955 ! salivary gland development GO:0007431 7 7 0,000 8,199E-03 0,02999943 ! glucosidase activity GO:0015926 8 7 0,000 8,199E-03 0,02996937 ! NuRD complex GO:0016581 8 7 0,000 8,199E-03 0,02993937 ! negative regulation of nuclear division GO:0051784 7 7 0,000 8,199E-03 0,02990943 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 8,199E-03 0,02987956 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 8,199E-03 0,02984974 ! response to redox state GO:0051775 8 7 0,000 8,199E-03 0,02981997 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 8,199E-03 0,02979027 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 8,199E-03 0,02976063 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 8,199E-03 0,02973105 ! actin monomer binding GO:0003785 7 7 0,000 8,199E-03 0,02970152 ! protein prenyltransferase activity GO:0008318 8 7 0,000 8,199E-03 0,02967206 ! endosome to lysosome transport GO:0008333 7 7 0,000 8,199E-03 0,02964265 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 8,199E-03 0,0296133 ! germ cell migration GO:0008354 7 7 0,000 8,199E-03 0,02958401 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 8,199E-03 0,02955478 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 8,199E-03 0,0295256 ! CoA-ligase activity GO:0016405 8 7 0,000 8,199E-03 0,02949648 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 8,199E-03 0,02946742 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 8,199E-03 0,02943842 ! embryonic heart tube development GO:0035050 8 7 0,000 8,199E-03 0,02940947 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 8,199E-03 0,02938058 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 8,199E-03 0,02935175 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 8,199E-03 0,02932298 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 8,199E-03 0,02929426 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 8,199E-03 0,02926559 ! adenylate kinase activity GO:0004017 8 7 0,000 8,199E-03 0,02923698 ! negative regulation of immune effector process GO:0002698 13 7 0,000 8,199E-03 0,02920843 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 8,199E-03 0,02917994 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 8,199E-03 0,0291515 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 9,365E-03 0,0332649 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 9,365E-03 0,03323254 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 9,365E-03 0,03320025 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 0,000 9,365E-03 0,03316801 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 9,365E-03 0,03313584 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 0,000 9,365E-03 0,03310374 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 9,365E-03 0,03307169 ! proteasome regulatory particle GO:0005838 8 8 0,000 9,365E-03 0,0330397 ! SMAD protein complex assembly GO:0007183 10 8 0,000 9,365E-03 0,03300778 ! protein self-association GO:0043621 8 8 0,000 9,365E-03 0,03297592 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 9,365E-03 0,03294412 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 9,365E-03 0,03291238 ! neurotransmitter uptake GO:0001504 8 8 0,000 9,365E-03 0,03288071 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 9,365E-03 0,03284909 ! guanylate cyclase activity GO:0004383 9 8 0,000 9,365E-03 0,03281754 ! troponin complex GO:0005861 8 8 0,000 9,365E-03 0,03278604 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 9,365E-03 0,03275461 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 9,365E-03 0,03272323 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 9,365E-03 0,03269192 ! microtubule bundle formation GO:0001578 8 8 0,000 9,365E-03 0,03266066 ! middle ear morphogenesis GO:0042474 10 8 0,000 9,365E-03 0,03262947 ! ganglioside metabolic process GO:0001573 8 8 0,000 9,365E-03 0,03259833 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 9,365E-03 0,03256726 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 9,365E-03 0,03253624 ! ciliary or flagellar motility GO:0001539 8 8 0,000 9,365E-03 0,03250529 ! pathogenesis GO:0009405 8 8 0,000 9,365E-03 0,03247439 ! pH reduction GO:0045851 9 8 0,000 9,365E-03 0,03244355 ! small protein activating enzyme activity GO:0008641 10 8 0,000 9,365E-03 0,03241277 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 9,365E-03 0,03238204 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 9,365E-03 0,03235138 ! hemoglobin metabolic process GO:0020027 8 8 0,000 9,365E-03 0,03232077 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 9,365E-03 0,03229022 ! arginine catabolic process GO:0006527 9 8 0,000 9,365E-03 0,03225973 ! T-tubule GO:0030315 9 8 0,000 9,365E-03 0,0322293 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 9,365E-03 0,03219892 ! histidine catabolic process GO:0006548 8 8 0,000 9,365E-03 0,0321686 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 9,365E-03 0,03213834 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 9,365E-03 0,03210813 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 9,365E-03 0,03207799 ! proline metabolic process GO:0006560 10 8 0,000 9,365E-03 0,03204789 ! L-serine metabolic process GO:0006563 9 8 0,000 9,365E-03 0,03201786 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 9,365E-03 0,03198788 ! melanosome membrane GO:0033162 9 8 0,000 9,365E-03 0,03195796 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 9,365E-03 0,03192809 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 9,365E-03 0,03189828 ! pericentriolar material GO:0000242 9 8 0,000 9,365E-03 0,03186852 ! reverse cholesterol transport GO:0043691 8 8 0,000 9,365E-03 0,03183882 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 9,365E-03 0,03180918 ! melanin metabolic process GO:0006582 10 8 0,000 9,365E-03 0,03177959 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 9,365E-03 0,03175005 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 9,365E-03 0,03172057 ! Golgi lumen GO:0005796 8 8 0,000 9,365E-03 0,03169115 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 9,365E-03 0,03166177 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 9,365E-03 0,03163246 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 9,365E-03 0,0316032 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 9,365E-03 0,03157399 ! stereocilium bundle GO:0032421 11 8 0,000 9,365E-03 0,03154483 ! forebrain cell migration GO:0021885 9 8 0,000 9,365E-03 0,03151573 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 9,365E-03 0,03148669 ! osteoblast development GO:0002076 11 8 0,000 9,365E-03 0,03145769 ! retinoic acid metabolic process GO:0042573 8 8 0,000 9,365E-03 0,03142875 ! retinol metabolic process GO:0042572 8 8 0,000 9,365E-03 0,03139987 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 9,365E-03 0,03137103 ! structural constituent of epidermis GO:0030280 9 8 0,000 9,365E-03 0,03134225 ! clathrin binding GO:0030276 10 8 0,000 9,365E-03 0,03131352 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 9,365E-03 0,03128485 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 9,365E-03 0,03125623 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 9,365E-03 0,03122766 ! motor axon guidance GO:0008045 8 8 0,000 9,365E-03 0,03119914 ! protein targeting to vacuole GO:0006623 8 8 0,000 9,365E-03 0,03117067 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 9,365E-03 0,03114226 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 9,365E-03 0,03111389 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 9,365E-03 0,03108558 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 9,365E-03 0,03105732 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 9,365E-03 0,03102911 ! protein-lipid complex assembly GO:0065005 8 8 0,000 9,365E-03 0,03100096 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 9,365E-03 0,03097285 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 9,365E-03 0,0309448 ! regulation of dopamine secretion GO:0014059 9 8 0,000 9,365E-03 0,03091679 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 9,365E-03 0,03088884 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 9,365E-03 0,03086093 ! subpallium development GO:0021544 8 8 0,000 9,365E-03 0,03083308 ! icosanoid secretion GO:0032309 10 8 0,000 9,365E-03 0,03080528 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 9,365E-03 0,03077753 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 9,365E-03 0,03074982 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 9,365E-03 0,03072217 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 9,365E-03 0,03069457 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 9,365E-03 0,03066702 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 9,365E-03 0,03063951 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 9,365E-03 0,03061206 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 9,365E-03 0,03058465 ! ubiquinone metabolic process GO:0006743 9 8 0,000 9,365E-03 0,03055729 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 9,365E-03 0,03052999 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 9,365E-03 0,03050273 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 9,365E-03 0,03047552 ! Wnt receptor activity GO:0042813 11 8 0,000 9,365E-03 0,03044836 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 9,365E-03 0,03042124 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 9,365E-03 0,03039418 ! detection of calcium ion GO:0005513 9 8 0,000 9,365E-03 0,03036716 ! negative regulation of glucose import GO:0046325 9 8 0,000 9,365E-03 0,03034019 ! blastocyst growth GO:0001832 8 8 0,000 9,365E-03 0,03031327 ! regulation of fibrinolysis GO:0051917 8 8 0,000 9,365E-03 0,0302864 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 9,365E-03 0,03025957 ! cerebellar cortex formation GO:0021697 9 8 0,000 9,365E-03 0,03023279 ! complement binding GO:0001848 11 8 0,000 9,365E-03 0,03020606 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 9,365E-03 0,03017938 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 9,365E-03 0,03015274 ! amino sugar catabolic process GO:0046348 8 8 0,000 9,365E-03 0,03012615 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 9,365E-03 0,03009961 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 9,365E-03 0,03007311 ! positive regulation of amine transport GO:0051954 9 8 0,000 9,365E-03 0,03004666 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 9,365E-03 0,03002026 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 9,365E-03 0,0299939 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 9,365E-03 0,02996759 ! Golgi transport complex GO:0017119 8 8 0,000 9,365E-03 0,02994133 ! positive regulation of protein ubiquitination GO:0031398 17 8 0,000 9,365E-03 0,02991511 ! GDP binding GO:0019003 9 8 0,000 9,365E-03 0,02988894 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 9,365E-03 0,02986281 ! prostate gland development GO:0030850 17 8 0,000 9,365E-03 0,02983673 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 9,365E-03 0,02981069 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 9,365E-03 0,0297847 ! phosphate transport GO:0006817 9 8 0,000 9,365E-03 0,02975876 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 9,365E-03 0,02973286 ! oligopeptide transport GO:0006857 8 8 0,000 9,365E-03 0,029707 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 9,365E-03 0,02968119 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 9,365E-03 0,02965543 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 9,365E-03 0,02962971 ! lipoprotein transport GO:0042953 9 8 0,000 9,365E-03 0,02960403 ! estrogen metabolic process GO:0008210 8 8 0,000 9,365E-03 0,0295784 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 9,365E-03 0,02955282 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 9,365E-03 0,02952727 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 9,365E-03 0,02950177 ! T-helper 1 type immune response GO:0042088 8 8 0,000 9,365E-03 0,02947632 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 9,365E-03 0,02945091 ! response to amphetamine GO:0001975 11 8 0,000 9,365E-03 0,02942554 ! mechanosensory behavior GO:0007638 8 8 0,000 9,365E-03 0,02940022 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 9,365E-03 0,02937494 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 9,365E-03 0,0293497 ! C-X-C chemokine binding GO:0019958 8 8 0,000 9,365E-03 0,02932451 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 9,365E-03 0,02929936 ! glycerolipid catabolic process GO:0046503 17 8 0,000 9,365E-03 0,02927425 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 9,365E-03 0,02924919 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 9,365E-03 0,02922417 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 9,365E-03 0,02919919 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 9,365E-03 0,02917426 ! pigment granule organization GO:0048753 9 8 0,000 9,365E-03 0,02914936 ! GTP-dependent protein binding GO:0030742 11 8 0,000 9,365E-03 0,02912451 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 9,365E-03 0,02909971 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 9,365E-03 0,02907494 ! regulation of pigmentation during development GO:0048070 11 8 0,000 9,365E-03 0,02905022 ! macrophage activation GO:0042116 8 8 0,000 9,365E-03 0,02902554 ! poly(A) RNA binding GO:0008143 8 8 0,000 9,365E-03 0,0290009 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 9,365E-03 0,0289763 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 9,365E-03 0,02895174 ! asymmetric protein localization GO:0008105 9 8 0,000 9,365E-03 0,02892723 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 9,365E-03 0,02890275 ! neurotrophin binding GO:0043121 10 8 0,000 9,365E-03 0,02887832 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 9,365E-03 0,02885393 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 9,365E-03 0,02882958 ! phagocytosis, engulfment GO:0006911 10 8 0,000 9,365E-03 0,02880527 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 9,365E-03 0,02878101 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 9,365E-03 0,02875678 ! UV protection GO:0009650 9 8 0,000 9,365E-03 0,02873259 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 9,365E-03 0,02870845 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 9,365E-03 0,02868434 ! glutathione peroxidase activity GO:0004602 17 8 0,000 9,365E-03 0,02866028 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 9,365E-03 0,02863626 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 9,365E-03 0,02861227 ! ferric iron binding GO:0008199 9 8 0,000 9,365E-03 0,02858833 ! response to UV-B GO:0010224 10 8 0,000 9,365E-03 0,02856443 ! intermediate filament organization GO:0045109 8 8 0,000 9,365E-03 0,02854056 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 9,365E-03 0,02851674 ! cellular extravasation GO:0045123 9 8 0,000 9,365E-03 0,02849296 ! skeletal muscle contraction GO:0003009 8 8 0,000 9,365E-03 0,02846921 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 9,365E-03 0,02844551 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 0,000 9,365E-03 0,02842184 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 9,365E-03 0,02839822 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 9,365E-03 0,02837463 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 9,365E-03 0,02835108 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 9,365E-03 0,02832757 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 9,365E-03 0,0283041 ! erythrocyte development GO:0048821 9 8 0,000 9,365E-03 0,02828067 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 9,365E-03 0,02825728 ! ribosome assembly GO:0042255 8 8 0,000 9,365E-03 0,02823393 ! postreplication repair GO:0006301 19 8 0,000 9,365E-03 0,02821061 ! gamma-tubulin binding GO:0043015 8 8 0,000 9,365E-03 0,02818734 ! NADPH oxidase complex GO:0043020 8 8 0,000 9,365E-03 0,0281641 ! mRNA cleavage GO:0006379 9 8 0,000 9,365E-03 0,0281409 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 9,365E-03 0,02811774 ! opioid receptor activity GO:0004985 8 8 0,000 9,365E-03 0,02809462 ! zymogen activation GO:0031638 9 8 0,000 9,365E-03 0,02807153 ! coenzyme A metabolic process GO:0015936 8 8 0,000 9,365E-03 0,02804848 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 9,365E-03 0,02802548 ! costamere GO:0043034 8 8 0,000 9,365E-03 0,0280025 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 9,365E-03 0,02797957 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 9,365E-03 0,02795667 ! sarcomere organization GO:0045214 9 8 0,000 9,365E-03 0,02793381 ! wide pore channel activity GO:0022829 9 8 0,000 9,365E-03 0,02791099 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 9,365E-03 0,02788821 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 9,365E-03 0,02786546 ! hormone catabolic process GO:0042447 9 8 0,000 9,365E-03 0,02784275 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 9,365E-03 0,02782008 ! cGMP biosynthetic process GO:0006182 9 8 0,000 9,365E-03 0,02779744 ! lysozyme activity GO:0003796 10 8 0,000 9,365E-03 0,02777484 ! death receptor binding GO:0005123 8 8 0,000 9,365E-03 0,02775228 ! protein modification by small protein removal GO:0070646 9 8 0,000 9,365E-03 0,02772975 ! adult feeding behavior GO:0008343 9 8 0,000 9,365E-03 0,02770726 ! microtubule basal body GO:0005932 8 8 0,000 9,365E-03 0,02768481 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 9,365E-03 0,02766239 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 9,365E-03 0,02764001 ! calcium-release channel activity GO:0015278 8 8 0,000 9,365E-03 0,02761767 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 9,365E-03 0,02759536 ! behavioral response to nicotine GO:0035095 9 8 0,000 9,365E-03 0,02757309 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 9,365E-03 0,02755085 ! adenosine deaminase activity GO:0004000 8 8 0,000 9,365E-03 0,02752865 ! NAD biosynthetic process GO:0009435 9 8 0,000 9,365E-03 0,02750649 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 0,01052958 0,03090258 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 0,01052958 0,03087773 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 0,01052958 0,03085293 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 0,01052958 0,03082817 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 0,01052958 0,03080345 ! myotube differentiation GO:0014902 9 9 0,000 0,01052958 0,03077877 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 0,01052958 0,03075412 ! N-glycan processing GO:0006491 10 9 0,000 0,01052958 0,03072952 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 0,01052958 0,03070496 ! actin-myosin filament sliding GO:0033275 11 9 0,000 0,01052958 0,03068043 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 0,01052958 0,03065595 ! RNA methylation GO:0001510 9 9 0,000 0,01052958 0,0306315 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 0,01052958 0,03060709 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 0,01052958 0,03058272 ! artery development GO:0060840 9 9 0,000 0,01052958 0,03055839 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 0,01052958 0,0305341 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 0,01052958 0,03050985 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 0,01052958 0,03048564 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 0,01052958 0,03046146 ! positive regulation of heart contraction GO:0045823 11 9 0,000 0,01052958 0,03043732 ! lipopolysaccharide binding GO:0001530 9 9 0,000 0,01052958 0,03041322 ! regulated secretory pathway GO:0045055 10 9 0,000 0,01052958 0,03038916 ! estrogen receptor binding GO:0030331 9 9 0,000 0,01052958 0,03036514 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 0,01052958 0,03034115 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 0,01052958 0,03031721 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 0,01052958 0,0302933 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 0,01052958 0,03026943 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! urea metabolic process GO:0019627 19 9 0,000 0,01052958 0,03024559 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 0,01052958 0,03022179 ! autophagic vacuole GO:0005776 11 9 0,000 0,01052958 0,03019804 ! Rac GTPase binding GO:0048365 10 9 0,000 0,01052958 0,03017431 ! response to dietary excess GO:0002021 9 9 0,000 0,01052958 0,03015063 ! regulation of sodium ion transport GO:0002028 10 9 0,000 0,01052958 0,03012698 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01052958 0,03010337 ! lens development in camera-type eye GO:0002088 9 9 0,000 0,01052958 0,0300798 ! male sex determination GO:0030238 9 9 0,000 0,01052958 0,03005626 ! positive regulation of vasodilation GO:0045909 19 9 0,000 0,01052958 0,03003276 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 0,01052958 0,0300093 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 0,01052958 0,02998587 ! male germ cell nucleus GO:0001673 11 9 0,000 0,01052958 0,02996248 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 0,01052958 0,02993913 ! copper ion homeostasis GO:0055070 9 9 0,000 0,01052958 0,02991581 ! protein heterooligomerization GO:0051291 10 9 0,000 0,01052958 0,02989253 ! spectrin GO:0008091 9 9 0,000 0,01052958 0,02986929 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 0,01052958 0,02984608 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 0,01052958 0,0298229 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 0,01052958 0,02979977 ! regulation of B cell differentiation GO:0045577 10 9 0,000 0,01052958 0,02977667 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 0,01052958 0,0297536 ! neural tube patterning GO:0021532 10 9 0,000 0,01052958 0,02973057 ! fucose catabolic process GO:0019317 10 9 0,000 0,01052958 0,02970758 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 0,01052958 0,02968462 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 0,01052958 0,0296617 ! sterol catabolic process GO:0016127 10 9 0,000 0,01052958 0,02963881 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 0,01052958 0,02961596 ! clathrin coat of coated pit GO:0030132 11 9 0,000 0,01052958 0,02959314 ! SNARE complex GO:0031201 11 9 0,000 0,01052958 0,02957036 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 0,01052958 0,02954762 ! negative regulation of glucose transport GO:0010829 10 9 0,000 0,01052958 0,0295249 ! methionine biosynthetic process GO:0009086 11 9 0,000 0,01052958 0,02950223 ! peptidoglycan binding GO:0042834 9 9 0,000 0,01052958 0,02947959 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 0,01052958 0,02945698 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 0,01052958 0,02943441 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 0,01052958 0,02941187 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 0,01052958 0,02938937 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 0,01052958 0,0293669 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 0,01052958 0,02934446 ! detection of bacterium GO:0016045 10 9 0,000 0,01052958 0,02932206 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 0,01052958 0,0292997 ! embryonic gut development GO:0048566 10 9 0,000 0,01052958 0,02927736 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 0,01052958 0,02925507 ! desmosome GO:0030057 10 9 0,000 0,01052958 0,0292328 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 0,01052958 0,02921057 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 0,01052958 0,02918837 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 0,01052958 0,02916621 ! actin filament polymerization GO:0030041 10 9 0,000 0,01052958 0,02914408 ! negative regulation of B cell activation GO:0050869 10 9 0,000 0,01052958 0,02912199 ! establishment of cell polarity GO:0030010 10 9 0,000 0,01052958 0,02909993 ! regulation of synapse organization GO:0050807 10 9 0,000 0,01052958 0,0290779 ! septin complex GO:0031105 10 9 0,000 0,01052958 0,0290559 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 0,01052958 0,02903394 ! anchoring collagen GO:0030934 9 9 0,000 0,01052958 0,02901201 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 0,01052958 0,02899011 ! regulation of developmental growth GO:0048638 11 9 0,000 0,01052958 0,02896825 ! GMP binding GO:0019002 11 9 0,000 0,01052958 0,02894642 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 0,01052958 0,02892462 ! virus-host interaction GO:0019048 13 9 0,000 0,01052958 0,02890286 ! pentose-phosphate shunt GO:0006098 11 9 0,000 0,01052958 0,02888113 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 0,01052958 0,02885943 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 0,01052958 0,02883776 ! non-recombinational repair GO:0000726 10 9 0,000 0,01052958 0,02881613 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 0,01052958 0,02879453 ! nuclear telomere cap complex GO:0000783 10 9 0,000 0,01052958 0,02877296 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 0,01052958 0,02875142 ! social behavior GO:0035176 10 9 0,000 0,01052958 0,02872992 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 0,01052958 0,02870845 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 0,01052958 0,02868701 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 0,01052958 0,0286656 ! mating GO:0007618 11 9 0,000 0,01052958 0,02864422 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 0,01052958 0,02862288 ! rhythmic behavior GO:0007622 11 9 0,000 0,01052958 0,02860156 ! phospholipid efflux GO:0033700 10 9 0,000 0,01052958 0,02858028 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 0,01052958 0,02855903 ! poly-purine tract binding GO:0070717 9 9 0,000 0,01052958 0,02853782 ! T cell proliferation GO:0042098 10 9 0,000 0,01052958 0,02851663 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 0,01052958 0,02849548 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 0,01052958 0,02847435 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 0,01052958 0,02845326 ! interleukin-1 binding GO:0019966 10 9 0,000 0,01052958 0,0284322 ! glucosyltransferase activity GO:0046527 9 9 0,000 0,01052958 0,02841117 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 0,01052958 0,02839017 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 0,01052958 0,0283692 ! ovulation GO:0030728 9 9 0,000 0,01052958 0,02834827 ! acid phosphatase activity GO:0003993 18 9 0,000 0,01052958 0,02832736 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 0,01052958 0,02830649 ! ER overload response GO:0006983 11 9 0,000 0,01052958 0,02828564 ! B cell proliferation GO:0042100 10 9 0,000 0,01052958 0,02826483 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 0,01052958 0,02824404 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 0,01052958 0,02822329 ! mannose metabolic process GO:0006013 13 9 0,000 0,01052958 0,02820257 ! lipid digestion GO:0044241 11 9 0,000 0,01052958 0,02818188 ! tumor necrosis factor binding GO:0043120 9 9 0,000 0,01052958 0,02816122 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 0,01052958 0,02814059 ! regulation of bone resorption GO:0045124 10 9 0,000 0,01052958 0,02811999 ! brain morphogenesis GO:0048854 9 9 0,000 0,01052958 0,02809942 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 0,01052958 0,02807888 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 0,01052958 0,02805836 ! synaptic vesicle membrane GO:0030672 9 9 0,000 0,01052958 0,02803788 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 0,01052958 0,02801743 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 0,01052958 0,02799701 ! kinesin binding GO:0019894 9 9 0,000 0,01052958 0,02797662 ! multicellular organismal aging GO:0010259 18 9 0,000 0,01052958 0,02795626 ! Ran GTPase binding GO:0008536 11 9 0,000 0,01052958 0,02793593 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 0,01052958 0,02791563 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 0,01052958 0,02789535 ! mRNA polyadenylation GO:0006378 10 9 0,000 0,01052958 0,02787511 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 0,01052958 0,0278549 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 0,01052958 0,02783471 ! prostaglandin receptor activity GO:0004955 11 9 0,000 0,01052958 0,02781456 ! caspase inhibitor activity GO:0043027 9 9 0,000 0,01052958 0,02779443 ! adrenoceptor activity GO:0004935 12 9 0,000 0,01052958 0,02777433 ! regulation of isotype switching GO:0045191 9 9 0,000 0,01052958 0,02775426 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 0,01052958 0,02773422 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 0,01052958 0,02771421 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 0,01052958 0,02769423 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 0,01052958 0,02767428 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 0,01052958 0,02765436 ! Notch binding GO:0005112 10 9 0,000 0,01052958 0,02763446 ! ATPase regulator activity GO:0060590 10 9 0,000 0,01052958 0,02761459 ! gamma-tubulin complex GO:0000930 19 9 0,000 0,01052958 0,02759476 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 0,01052958 0,02757495 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 0,01052958 0,02755517 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 0,01052958 0,02753541 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 0,01052958 0,02751569 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 0,000 0,01169298 0,03053399 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,01169298 0,03051215 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,01169298 0,03049034 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,01169298 0,03046856 ! sleep GO:0030431 11 10 0,000 0,01169298 0,03044681 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,01169298 0,03042509 ! lipid particle GO:0005811 10 10 0,000 0,01169298 0,03040341 ! filopodium assembly GO:0046847 14 10 0,000 0,01169298 0,03038175 ! UTP metabolic process GO:0046051 12 10 0,000 0,01169298 0,03036013 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,01169298 0,03033853 ! guanylate kinase activity GO:0004385 14 10 0,000 0,01169298 0,03031697 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,01169298 0,03029544 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,01169298 0,03027394 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,01169298 0,03025247 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,01169298 0,03023103 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,01169298 0,03020962 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,01169298 0,03018824 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,01169298 0,03016689 ! lung alveolus development GO:0048286 11 10 0,000 0,01169298 0,03014557 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,01169298 0,03012428 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01169298 0,03010302 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,01169298 0,03008179 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,01169298 0,03006059 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,01169298 0,03003942 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,01169298 0,03001828 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,01169298 0,02999717 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,01169298 0,02997609 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,01169298 0,02995504 ! histidine metabolic process GO:0006547 10 10 0,000 0,01169298 0,02993402 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,01169298 0,02991303 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,01169298 0,02989207 ! death receptor activity GO:0005035 11 10 0,000 0,01169298 0,02987113 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,01169298 0,02985023 ! entry into host cell GO:0030260 11 10 0,000 0,01169298 0,02982936 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,01169298 0,02980851 ! filamentous actin GO:0031941 11 10 0,000 0,01169298 0,02978769 ! behavioral fear response GO:0001662 12 10 0,000 0,01169298 0,02976691 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,01169298 0,02974615 ! negative regulation of ossification GO:0030279 12 10 0,000 0,01169298 0,02972542 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,01169298 0,02970472 ! macrophage differentiation GO:0030225 11 10 0,000 0,01169298 0,02968405 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,01169298 0,02966341 ! recycling endosome membrane GO:0055038 11 10 0,000 0,01169298 0,02964279 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,01169298 0,02962221 ! snRNA metabolic process GO:0016073 10 10 0,000 0,01169298 0,02960165 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,01169298 0,02958112 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 0,01169298 0,02956062 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,01169298 0,02954015 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,01169298 0,02951971 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,01169298 0,02949929 ! induction of an organ GO:0001759 12 10 0,000 0,01169298 0,02947891 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,01169298 0,02945855 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,01169298 0,02943822 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,01169298 0,02941792 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,01169298 0,02939764 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,01169298 0,0293774 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,01169298 0,02935718 ! ribonuclease P activity GO:0004526 10 10 0,000 0,01169298 0,02933699 ! COPI vesicle coat GO:0030126 12 10 0,000 0,01169298 0,02931682 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,01169298 0,02929669 ! vitamin transporter activity GO:0051183 12 10 0,000 0,01169298 0,02927658 ! snRNA binding GO:0017069 11 10 0,000 0,01169298 0,0292565 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,01169298 0,02923645 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,01169298 0,02921642 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,01169298 0,02919643 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,01169298 0,02917646 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,01169298 0,02915651 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,01169298 0,0291366 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,01169298 0,02911671 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,01169298 0,02909685 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,01169298 0,02907701 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,01169298 0,02905721 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 0,01169298 0,02903743 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 0,01169298 0,02901767 ! extracellular matrix binding GO:0050840 11 10 0,000 0,01169298 0,02899795 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,01169298 0,02897825 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,01169298 0,02895857 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,01169298 0,02893893 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,01169298 0,02891931 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 0,01169298 0,02889971 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,01169298 0,02888015 ! thyroid gland development GO:0030878 12 10 0,000 0,01169298 0,02886061 ! DNA bending activity GO:0008301 11 10 0,000 0,01169298 0,02884109 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,01169298 0,02882161 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,01169298 0,02880215 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,01169298 0,02878271 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,01169298 0,0287633 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,01169298 0,02874392 ! regulation of glycolysis GO:0006110 11 10 0,000 0,01169298 0,02872456 ! nucleotidase activity GO:0008252 10 10 0,000 0,01169298 0,02870523 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,01169298 0,02868593 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,01169298 0,02866665 ! androgen metabolic process GO:0008209 11 10 0,000 0,01169298 0,0286474 ! lateral plasma membrane GO:0016328 13 10 0,000 0,01169298 0,02862817 ! MAP kinase kinase activity GO:0004708 12 10 0,000 0,01169298 0,02860897 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,01169298 0,0285898 ! startle response GO:0001964 13 10 0,000 0,01169298 0,02857065 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,01169298 0,02855153 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,01169298 0,02853243 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 0,01169298 0,02851335 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,01169298 0,02849431 ! spinal cord patterning GO:0021511 12 10 0,000 0,01169298 0,02847529 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,01169298 0,02845629 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,01169298 0,02843732 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,01169298 0,02841837 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 0,01169298 0,02839945 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,01169298 0,02838056 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,01169298 0,02836169 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,01169298 0,02834284 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,01169298 0,02832402 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,01169298 0,02830523 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,01169298 0,02828646 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,01169298 0,02826771 ! adult heart development GO:0007512 14 10 0,000 0,01169298 0,02824899 ! neuromuscular junction development GO:0007528 12 10 0,000 0,01169298 0,0282303 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,01169298 0,02821163 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,01169298 0,02819298 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,01169298 0,02817436 ! signalosome GO:0008180 10 10 0,000 0,01169298 0,02815576 ! lysophospholipase activity GO:0004622 19 10 0,000 0,01169298 0,02813719 ! prefoldin complex GO:0016272 10 10 0,000 0,01169298 0,02811864 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,01169298 0,02810012 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,01169298 0,02808162 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,01169298 0,02806314 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,01169298 0,02804469 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,01169298 0,02802627 ! gland morphogenesis GO:0022612 11 10 0,000 0,01169298 0,02800787 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,01169298 0,02798949 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,01169298 0,02797113 ! peptide transporter activity GO:0015197 10 10 0,000 0,01169298 0,0279528 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,01169298 0,0279345 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,01169298 0,02791622 ! muscle maintenance GO:0046716 10 10 0,000 0,01169298 0,02789796 ! acid secretion GO:0046717 12 10 0,000 0,01169298 0,02787972 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,01169298 0,02786151 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,01169298 0,02784333 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,01169298 0,02782517 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,01169298 0,02780703 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,01169298 0,02778891 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,01169298 0,02777082 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,01169298 0,02775275 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,01169298 0,02773471 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 0,01169298 0,02771669 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,01169298 0,02769869 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,01169298 0,02768071 ! water channel activity GO:0015250 15 10 0,000 0,01169298 0,02766276 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,01169298 0,02764483 ! regulation of embryonic development GO:0045995 12 10 0,000 0,01169298 0,02762693 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 0,000 0,01169298 0,02760905 ! acrosome reaction GO:0007340 12 10 0,000 0,01169298 0,02759119 ! mitochondrion localization GO:0051646 10 10 0,000 0,01169298 0,02757335 ! cilium part GO:0044441 10 10 0,000 0,01169298 0,02755554 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,01285507 0,03027456 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,01285507 0,03025503 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,01285507 0,03023552 ! centriole GO:0005814 11 11 0,000 0,01285507 0,03021604 ! cadmium ion binding GO:0046870 15 11 0,000 0,01285507 0,03019658 ! hemoglobin complex GO:0005833 13 11 0,000 0,01285507 0,03017715 ! CTP metabolic process GO:0046036 13 11 0,000 0,01285507 0,03015774 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,01285507 0,03013836 ! response to pain GO:0048265 12 11 0,000 0,01285507 0,03011901 ! regulation of viral genome replication GO:0045069 13 11 0,000 0,01285507 0,03009967 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,01285507 0,03008037 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,01285507 0,03006109 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,01285507 0,03004183 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,01285507 0,03002259 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01285507 0,03000339 ! peptide antigen binding GO:0042605 14 11 0,000 0,01285507 0,0299842 ! polyamine metabolic process GO:0006595 11 11 0,000 0,01285507 0,02996504 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,01285507 0,02994591 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,01285507 0,0299268 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,01285507 0,02990771 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,01285507 0,02988865 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,01285507 0,02986961 ! protein homotetramerization GO:0051289 13 11 0,000 0,01285507 0,0298506 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,01285507 0,02983161 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,01285507 0,02981265 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,01285507 0,02979371 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,01285507 0,02977479 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,01285507 0,0297559 ! response to dsRNA GO:0043331 21 11 0,000 0,01285507 0,02973703 ! response to amine stimulus GO:0014075 15 11 0,000 0,01285507 0,02971818 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,01285507 0,02969936 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,01285507 0,02968057 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,01285507 0,02966179 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,01285507 0,02964304 ! retinal binding GO:0016918 11 11 0,000 0,01285507 0,02962432 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,01285507 0,02960561 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,01285507 0,02958694 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,01285507 0,02956828 ! autonomic nervous system development GO:0048483 12 11 0,000 0,01285507 0,02954965 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,01285507 0,02953104 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,01285507 0,02951246 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,01285507 0,02949389 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,01285507 0,02947536 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,01285507 0,02945684 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,01285507 0,02943835 ! regulation of epidermis development GO:0045682 14 11 0,000 0,01285507 0,02941988 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,01285507 0,02940144 ! midbrain development GO:0030901 12 11 0,000 0,01285507 0,02938302 ! musculoskeletal movement GO:0050881 12 11 0,000 0,01285507 0,02936462 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 0,01285507 0,02934624 ! regulation of RNA stability GO:0043487 13 11 0,000 0,01285507 0,02932789 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,01285507 0,02930956 ! cell killing GO:0001906 13 11 0,000 0,01285507 0,02929125 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,01285507 0,02927297 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,01285507 0,02925471 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,01285507 0,02923647 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 0,01285507 0,02921825 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 0,01285507 0,02920006 ! folic acid binding GO:0005542 12 11 0,000 0,01285507 0,02918189 ! mRNA 3'-end processing GO:0031124 12 11 0,000 0,01285507 0,02916374 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,01285507 0,02914561 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,01285507 0,02912751 ! microspike assembly GO:0030035 15 11 0,000 0,01285507 0,02910943 ! lamellipodium assembly GO:0030032 22 11 0,000 0,01285507 0,02909137 ! fibrillar collagen GO:0005583 12 11 0,000 0,01285507 0,02907334 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,01285507 0,02905532 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,01285507 0,02903733 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,01285507 0,02901936 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,01285507 0,02900142 ! synaptonemal complex GO:0000795 11 11 0,000 0,01285507 0,02898349 ! reproductive cellular process GO:0048610 13 11 0,000 0,01285507 0,02896559 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,01285507 0,02894771 ! positive regulation of B cell proliferation GO:0030890 15 11 0,000 0,01285507 0,02892985 ! Golgi vesicle budding GO:0048194 12 11 0,000 0,01285507 0,02891202 ! response to cAMP GO:0051591 11 11 0,000 0,01285507 0,0288942 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,01285507 0,02887641 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,01285507 0,02885864 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01285507 0,02884089 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,01285507 0,02882317 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,01285507 0,02880546 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,01285507 0,02878778 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 0,01285507 0,02877012 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,01285507 0,02875248 ! drug transport GO:0015893 12 11 0,000 0,01285507 0,02873486 ! FMN binding GO:0010181 12 11 0,000 0,01285507 0,02871726 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,01285507 0,02869969 ! water transporter activity GO:0005372 17 11 0,000 0,01285507 0,02868214 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,01285507 0,0286646 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01285507 0,02864709 ! multicellular organism growth GO:0035264 12 11 0,000 0,01285507 0,0286296 ! integrator complex GO:0032039 11 11 0,000 0,01285507 0,02861214 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,01285507 0,02859469 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,01285507 0,02857727 ! brush border membrane GO:0031526 12 11 0,000 0,01285507 0,02855986 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,01285507 0,02854248 ! macroautophagy GO:0016236 12 11 0,000 0,01285507 0,02852512 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,01285507 0,02850778 ! neuromuscular junction GO:0031594 12 11 0,000 0,01285507 0,02849046 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,01285507 0,02847316 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 0,01285507 0,02845588 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,01285507 0,02843863 ! response to antibiotic GO:0046677 13 11 0,000 0,01285507 0,02842139 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,01285507 0,02840418 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,01285507 0,02838698 ! proteasome accessory complex GO:0022624 11 11 0,000 0,01285507 0,02836981 ! neuroblast proliferation GO:0007405 13 11 0,000 0,01285507 0,02835266 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,01285507 0,02833552 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,01285507 0,02831841 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,01285507 0,02830132 ! protein kinase C binding GO:0005080 11 11 0,000 0,01285507 0,02828425 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,01285507 0,0282672 ! male genitalia development GO:0030539 15 11 0,000 0,01285507 0,02825018 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,01285507 0,02823317 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,01285507 0,02821618 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,01285507 0,02819921 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,01285507 0,02818227 ! arylsulfatase activity GO:0004065 12 11 0,000 0,01285507 0,02816534 ! sterol transporter activity GO:0015248 11 11 0,000 0,01285507 0,02814844 ! response to nicotine GO:0035094 13 11 0,000 0,01285507 0,02813155 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01285507 0,02811468 ! rRNA transcription GO:0009303 12 12 0,000 0,01401586 0,03063502 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,01401586 0,03061668 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,01401586 0,03059835 ! superoxide anion generation GO:0042554 12 12 0,000 0,01401586 0,03058005 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,01401586 0,03056177 ! regulation of S phase GO:0033261 16 12 0,000 0,01401586 0,03054352 ! regulation of chemokine production GO:0032642 13 12 0,000 0,01401586 0,03052528 ! male meiosis GO:0007140 12 12 0,000 0,01401586 0,03050707 ! signal complex assembly GO:0007172 15 12 0,000 0,01401586 0,03048888 ! GTP metabolic process GO:0046039 14 12 0,000 0,01401586 0,03047071 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,01401586 0,03045256 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,01401586 0,03043443 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,01401586 0,03041633 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,01401586 0,03039825 ! cartilage condensation GO:0001502 14 12 0,000 0,01401586 0,03038018 ! polysome GO:0005844 14 12 0,000 0,01401586 0,03036214 ! hippocampus development GO:0021766 13 12 0,000 0,01401586 0,03034412 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,01401586 0,03032613 ! beta-amyloid binding GO:0001540 12 12 0,000 0,01401586 0,03030815 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,01401586 0,03029019 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,01401586 0,03027226 ! regulation of exit from mitosis GO:0007096 31 12 0,000 0,01401586 0,03025435 ! chylomicron GO:0042627 13 12 0,000 0,01401586 0,03023646 ! T cell selection GO:0045058 22 12 0,000 0,01401586 0,03021859 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,01401586 0,03020074 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,01401586 0,03018291 ! WW domain binding GO:0050699 12 12 0,000 0,01401586 0,0301651 ! methionine metabolic process GO:0006555 14 12 0,000 0,01401586 0,03014732 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,01401586 0,03012955 ! glycine metabolic process GO:0006544 14 12 0,000 0,01401586 0,03011181 ! plasma membrane organization GO:0007009 12 12 0,000 0,01401586 0,03009408 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01401586 0,03007638 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,01401586 0,0300587 ! Golgi organization GO:0007030 15 12 0,000 0,01401586 0,03004104 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01401586 0,0300234 ! mitotic spindle organization GO:0007052 13 12 0,000 0,01401586 0,03000578 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,01401586 0,02998818 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,01401586 0,0299706 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,01401586 0,02995305 ! temperature homeostasis GO:0001659 13 12 0,000 0,01401586 0,02993551 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,01401586 0,02991799 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01401586 0,0299005 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01401586 0,02988302 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,01401586 0,02986557 ! axon cargo transport GO:0008088 13 12 0,000 0,01401586 0,02984813 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,01401586 0,02983072 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,01401586 0,02981332 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,01401586 0,02979595 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,01401586 0,0297786 ! basal lamina GO:0005605 12 12 0,000 0,01401586 0,02976126 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,01401586 0,02974395 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,01401586 0,02972666 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,01401586 0,02970938 ! biomineral formation GO:0031214 14 12 0,000 0,01401586 0,02969213 ! water homeostasis GO:0030104 12 12 0,000 0,01401586 0,0296749 ! promoter binding GO:0010843 14 12 0,000 0,01401586 0,02965768 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,01401586 0,02964049 ! intestinal absorption GO:0050892 14 12 0,000 0,01401586 0,02962332 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,01401586 0,02960617 ! oocyte differentiation GO:0009994 13 12 0,000 0,01401586 0,02958903 ! oxygen transport GO:0015671 13 12 0,000 0,01401586 0,02957192 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,01401586 0,02955483 ! cholesterol efflux GO:0033344 13 12 0,000 0,01401586 0,02953775 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,01401586 0,0295207 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,01401586 0,02950366 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,01401586 0,02948665 ! tropomyosin binding GO:0005523 12 12 0,000 0,01401586 0,02946965 ! blastocyst formation GO:0001825 13 12 0,000 0,01401586 0,02945268 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,01401586 0,02943572 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,01401586 0,02941879 ! mannose binding GO:0005537 13 12 0,000 0,01401586 0,02940187 ! defense response to fungus GO:0050832 12 12 0,000 0,01401586 0,02938497 ! embryonic placenta development GO:0001892 16 12 0,000 0,01401586 0,02936809 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01401586 0,02935123 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,01401586 0,02933439 ! acyl-CoA binding GO:0000062 12 12 0,000 0,01401586 0,02931757 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,01401586 0,02930077 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,01401586 0,02928399 ! copper ion transport GO:0006825 12 12 0,000 0,01401586 0,02926723 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,01401586 0,02925049 ! inositol metabolic process GO:0006020 21 12 0,000 0,01401586 0,02923376 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,01401586 0,02921706 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,01401586 0,02920037 ! protein complex disassembly GO:0043241 15 12 0,000 0,01401586 0,0291837 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,01401586 0,02916706 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,01401586 0,02915043 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,01401586 0,02913382 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,01401586 0,02911723 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,01401586 0,02910065 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,01401586 0,0290841 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,01401586 0,02906757 ! endoderm development GO:0007492 13 12 0,000 0,01401586 0,02905105 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,01401586 0,02903455 ! focal adhesion formation GO:0048041 16 12 0,000 0,01401586 0,02901808 ! T cell receptor complex GO:0042101 31 12 0,000 0,01401586 0,02900162 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,01401586 0,02898518 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,01401586 0,02896875 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,01401586 0,02895235 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,01401586 0,02893596 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,01401586 0,0289196 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,01401586 0,02890325 ! retinol binding GO:0019841 12 12 0,000 0,01401586 0,02888692 ! regulation of organ growth GO:0046620 12 12 0,000 0,01401586 0,02887061 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,01401586 0,02885432 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,01401586 0,02883804 ! histone acetylation GO:0016573 13 12 0,000 0,01401586 0,02882179 ! ribosome binding GO:0043022 13 12 0,000 0,01401586 0,02880555 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,01401586 0,02878933 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,01401586 0,02877313 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,01401586 0,02875695 ! tissue regeneration GO:0042246 12 12 0,000 0,01401586 0,02874078 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,01401586 0,02872463 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,01401586 0,02870851 ! germ cell nucleus GO:0043073 14 12 0,000 0,01401586 0,0286924 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,01401586 0,0286763 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,01401586 0,02866023 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01401586 0,02864417 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01401586 0,02862813 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,01401586 0,02861211 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,01401586 0,02859611 ! dopamine metabolic process GO:0042417 15 12 0,000 0,01401586 0,02858013 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,01401586 0,02856416 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,01401586 0,02854821 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,01401586 0,02853228 ! bacterial binding GO:0008367 14 12 0,000 0,01401586 0,02851637 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01401586 0,02850047 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,01401586 0,0284846 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,01401586 0,02846874 ! localization within membrane GO:0051668 13 12 0,000 0,01401586 0,02845289 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,01401586 0,02843707 ! axoneme part GO:0044447 12 12 0,000 0,01401586 0,02842126 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01517534 0,03075536 ! neuron maturation GO:0042551 14 13 0,000 0,01517534 0,03073828 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01517534 0,03072123 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01517534 0,03070419 ! bone remodeling GO:0046849 14 13 0,000 0,01517534 0,03068717 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01517534 0,03067017 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01517534 0,03065318 ! striated muscle thin filament GO:0005865 14 13 0,000 0,01517534 0,03063622 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01517534 0,03061928 ! organelle fusion GO:0048284 16 13 0,000 0,01517534 0,03060235 ! palate development GO:0060021 15 13 0,000 0,01517534 0,03058544 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01517534 0,03056855 ! arginine metabolic process GO:0006525 14 13 0,000 0,01517534 0,03055168 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01517534 0,03053483 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01517534 0,030518 ! response to retinoic acid GO:0032526 17 13 0,000 0,01517534 0,03050119 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01517534 0,03048439 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01517534 0,03046761 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01517534 0,03045085 ! fear response GO:0042596 15 13 0,000 0,01517534 0,03043411 ! epithelial cell development GO:0002064 22 13 0,000 0,01517534 0,03041739 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,01517534 0,03040069 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01517534 0,030384 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01517534 0,03036733 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01517534 0,03035069 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01517534 0,03033406 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01517534 0,03031744 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,01517534 0,03030085 ! cranial nerve development GO:0021545 15 13 0,000 0,01517534 0,03028427 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,01517534 0,03026772 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01517534 0,03025118 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,01517534 0,03023465 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01517534 0,03021815 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01517534 0,03020166 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01517534 0,0301852 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01517534 0,03016875 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01517534 0,03015232 ! NADP metabolic process GO:0006739 15 13 0,000 0,01517534 0,0301359 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01517534 0,03011951 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01517534 0,03010313 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01517534 0,03008677 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01517534 0,03007042 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01517534 0,0300541 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01517534 0,03003779 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01517534 0,0300215 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01517534 0,03000523 ! ADP binding GO:0043531 15 13 0,000 0,01517534 0,02998898 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01517534 0,02997274 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01517534 0,02995652 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01517534 0,02994032 ! neuron fate specification GO:0048665 25 13 0,000 0,01517534 0,02992414 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01517534 0,02990797 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01517534 0,02989182 ! water transport GO:0006833 18 13 0,000 0,01517534 0,02987569 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01517534 0,02985957 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01517534 0,02984348 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01517534 0,0298274 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01517534 0,02981134 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01517534 0,02979529 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,01517534 0,02977926 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01517534 0,02976325 ! myoblast differentiation GO:0045445 15 13 0,000 0,01517534 0,02974726 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01517534 0,02973128 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01517534 0,02971533 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01517534 0,02969938 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01517534 0,02968346 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,01517534 0,02966755 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01517534 0,02965166 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01517534 0,02963579 ! exocrine system development GO:0035272 14 13 0,000 0,01517534 0,02961993 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01517534 0,02960409 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01517534 0,02958827 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01517534 0,02957246 ! L-glutamate transport GO:0015813 14 13 0,000 0,01517534 0,02955667 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01517534 0,0295409 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01517534 0,02952515 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01517534 0,02950941 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01517534 0,02949369 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01517534 0,02947798 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,01517534 0,02946229 ! genitalia development GO:0048806 18 13 0,000 0,01517534 0,02944662 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01517534 0,02943097 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01517534 0,02941533 ! MHC class I protein binding GO:0042288 23 13 0,000 0,01517534 0,02939971 ! histone deacetylation GO:0016575 14 13 0,000 0,01517534 0,0293841 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01517534 0,02936852 ! DNA methylation GO:0006306 15 13 0,000 0,01517534 0,02935294 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01517534 0,02933739 ! chromatin silencing GO:0006342 13 13 0,000 0,01517534 0,02932185 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01517534 0,02930633 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01517534 0,02929082 ! T cell homeostasis GO:0043029 14 13 0,000 0,01517534 0,02927533 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01517534 0,02925986 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01517534 0,0292444 ! response to gamma radiation GO:0010332 14 13 0,000 0,01517534 0,02922896 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01517534 0,02921354 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01517534 0,02919813 ! purine base metabolic process GO:0006144 15 13 0,000 0,01517534 0,02918274 ! cAMP binding GO:0030552 15 13 0,000 0,01517534 0,02916736 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01517534 0,029152 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01517534 0,02913666 ! regulation of axon extension GO:0030516 16 13 0,000 0,01517534 0,02912133 ! drug transporter activity GO:0015238 14 13 0,000 0,01517534 0,02910602 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01517534 0,02909073 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01517534 0,02907545 ! response to cold GO:0009409 13 13 0,000 0,01517534 0,02906018 ! cadherin binding GO:0045296 16 13 0,000 0,01517534 0,02904494 ! nucleolar part GO:0044452 13 13 0,000 0,01517534 0,02902971 ! tRNA modification GO:0006400 14 14 0,000 0,01633353 0,03122888 ! cis-Golgi network GO:0005801 16 14 0,000 0,01633353 0,03121252 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,01633353 0,03119618 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,01633353 0,03117986 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,01633353 0,03116355 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,01633353 0,03114726 ! peroxisomal transport GO:0043574 14 14 0,000 0,01633353 0,03113098 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,01633353 0,03111473 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,01633353 0,03109849 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,01633353 0,03108227 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,01633353 0,03106606 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,01633353 0,03104987 ! caspase activator activity GO:0008656 16 14 0,000 0,01633353 0,0310337 ! MHC class II protein complex GO:0042613 19 14 0,000 0,01633353 0,03101755 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01633353 0,03100141 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,01633353 0,03098529 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,01633353 0,03096918 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,01633353 0,03095309 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01633353 0,03093702 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,01633353 0,03092097 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,01633353 0,03090493 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,01633353 0,03088891 ! response to vitamin A GO:0033189 18 14 0,000 0,01633353 0,0308729 ! actin filament bundle formation GO:0051017 16 14 0,000 0,01633353 0,03085692 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,01633353 0,03084094 ! plasma membrane fusion GO:0045026 15 14 0,000 0,01633353 0,03082499 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,01633353 0,03080905 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,01633353 0,03079313 ! protein export from nucleus GO:0006611 14 14 0,000 0,01633353 0,03077722 ! presynaptic membrane GO:0042734 14 14 0,000 0,01633353 0,03076133 ! negative regulation of immune response GO:0050777 21 14 0,000 0,01633353 0,03074546 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,01633353 0,03072961 ! neural crest cell migration GO:0001755 15 14 0,000 0,01633353 0,03071377 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,01633353 0,03069794 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,01633353 0,03068213 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,01633353 0,03066634 ! cofactor transport GO:0051181 16 14 0,000 0,01633353 0,03065057 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01633353 0,03063481 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,01633353 0,03061907 ! cobalt ion binding GO:0050897 14 14 0,000 0,01633353 0,03060334 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01633353 0,03058763 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,01633353 0,03057194 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,01633353 0,03055626 ! gas transport GO:0015669 15 14 0,000 0,01633353 0,0305406 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,01633353 0,03052495 ! heme biosynthetic process GO:0006783 14 14 0,000 0,01633353 0,03050932 ! cerebellar cortex development GO:0021695 16 14 0,000 0,01633353 0,03049371 ! insulin secretion GO:0030073 17 14 0,000 0,01633353 0,03047811 ! tRNA binding GO:0000049 16 14 0,000 0,01633353 0,03046253 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,01633353 0,03044696 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,01633353 0,03043141 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,01633353 0,03041588 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,01633353 0,03040036 ! regulation of B cell proliferation GO:0030888 18 14 0,000 0,01633353 0,03038486 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,01633353 0,03036937 ! MAP kinase activity GO:0004707 16 14 0,000 0,01633353 0,0303539 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,01633353 0,03033844 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,01633353 0,03032301 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,01633353 0,03030758 ! C-C chemokine binding GO:0019957 15 14 0,000 0,01633353 0,03029217 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,01633353 0,03027678 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,01633353 0,0302614 ! response to osmotic stress GO:0006970 17 14 0,000 0,01633353 0,03024604 ! fructose metabolic process GO:0006000 15 14 0,000 0,01633353 0,0302307 ! telomeric DNA binding GO:0042162 17 14 0,000 0,01633353 0,03021537 ! monoamine transport GO:0015844 15 14 0,000 0,01633353 0,03020005 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01633353 0,03018475 ! dendritic spine GO:0043197 15 14 0,000 0,01633353 0,03016947 ! stem cell development GO:0048864 14 14 0,000 0,01633353 0,0301542 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,01633353 0,03013895 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,01633353 0,03012371 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,01633353 0,03010849 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,01633353 0,03009329 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01633353 0,03007809 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 0,000 0,01633353 0,03006292 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,01633353 0,03004776 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01633353 0,03003261 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,01633353 0,03001748 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,01633353 0,03000237 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,01633353 0,02998727 ! mannosidase activity GO:0015923 19 14 0,000 0,01633353 0,02997219 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,01633353 0,02995712 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,01633353 0,02994206 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,01633353 0,02992702 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,01633353 0,029912 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,01633353 0,02989699 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01633353 0,029882 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,01633353 0,02986702 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,01633353 0,02985206 ! sperm-egg recognition GO:0035036 17 14 0,000 0,01633353 0,02983711 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,01633353 0,02982217 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,01633353 0,02980726 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,01633353 0,02979235 ! positive regulation of translation GO:0045727 17 15 0,000 0,01749041 0,03188656 ! nuclear replication fork GO:0043596 26 15 0,000 0,01749041 0,03187064 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,01749041 0,03185473 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,01749041 0,03183883 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,01749041 0,03182295 ! endothelial cell migration GO:0043542 16 15 0,000 0,01749041 0,03180709 ! lipid phosphorylation GO:0046834 19 15 0,000 0,01749041 0,03179124 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01749041 0,03177541 ! response to vitamin GO:0033273 19 15 0,000 0,01749041 0,03175959 ! gene silencing by RNA GO:0031047 17 15 0,000 0,01749041 0,03174379 ! striated muscle thick filament GO:0005863 16 15 0,000 0,01749041 0,031728 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,01749041 0,03171223 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,01749041 0,03169648 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,01749041 0,03168074 ! glutamate metabolic process GO:0006536 17 15 0,000 0,01749041 0,03166502 ! pituitary gland development GO:0021983 16 15 0,000 0,01749041 0,03164931 ! cholesterol binding GO:0015485 15 15 0,000 0,01749041 0,03163362 ! NAD metabolic process GO:0019674 17 15 0,000 0,01749041 0,03161795 ! protease binding GO:0002020 20 15 0,000 0,01749041 0,03160229 ! regulation of heart rate GO:0002027 20 15 0,000 0,01749041 0,03158664 ! actin filament bundle GO:0032432 18 15 0,000 0,01749041 0,03157101 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,01749041 0,0315554 ! regulation of exocytosis GO:0017157 16 15 0,000 0,01749041 0,0315398 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01749041 0,03152422 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,01749041 0,03150865 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,01749041 0,0314931 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,01749041 0,03147756 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,01749041 0,03146204 ! neuron recognition GO:0008038 18 15 0,000 0,01749041 0,03144653 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,01749041 0,03143104 ! filopodium GO:0030175 17 15 0,000 0,01749041 0,03141557 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,01749041 0,03140011 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,01749041 0,03138466 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,01749041 0,03136923 ! peptide hormone binding GO:0017046 16 15 0,000 0,01749041 0,03135382 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,01749041 0,03133842 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,01749041 0,03132303 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,01749041 0,03130766 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,01749041 0,03129231 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,01749041 0,03127697 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,01749041 0,03126164 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,01749041 0,03124634 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,01749041 0,03123104 ! developmental induction GO:0031128 17 15 0,000 0,01749041 0,03121576 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,01749041 0,0312005 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,01749041 0,03118525 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,01749041 0,03117001 ! lactation GO:0007595 17 15 0,000 0,01749041 0,03115479 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,01749041 0,03113959 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01749041 0,0311244 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01749041 0,03110922 ! double-strand break repair via homologous recombination GO:0000724 36 15 0,000 0,01749041 0,03109406 GO:0000725|recombinational repair, ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,01749041 0,03107892 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,01749041 0,03106379 ! sulfate transport GO:0008272 16 15 0,000 0,01749041 0,03104867 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,01749041 0,03103357 ! bile acid metabolic process GO:0008206 17 15 0,000 0,01749041 0,03101848 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,01749041 0,03100341 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,01749041 0,03098835 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,01749041 0,03097331 ! heart looping GO:0001947 18 15 0,000 0,01749041 0,03095828 ! protein kinase C activity GO:0004697 17 15 0,000 0,01749041 0,03094327 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,01749041 0,03092827 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,01749041 0,03091328 ! pigmentation during development GO:0048066 17 15 0,000 0,01749041 0,03089831 ! cytokine metabolic process GO:0042107 15 15 0,000 0,01749041 0,03088336 ! vesicle coating GO:0006901 17 15 0,000 0,01749041 0,03086842 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,01749041 0,03085349 ! neutral amino acid transport GO:0015804 18 15 0,000 0,01749041 0,03083858 ! L-amino acid transport GO:0015807 16 15 0,000 0,01749041 0,03082368 ! microfilament motor activity GO:0000146 15 15 0,000 0,01749041 0,0308088 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,01749041 0,03079393 ! regulation of vasodilation GO:0042312 25 15 0,000 0,01749041 0,03077907 ! DNA replication initiation GO:0006270 15 15 0,000 0,01749041 0,03076423 ! taste receptor activity GO:0008527 15 15 0,000 0,01749041 0,03074941 ! cellular pigmentation GO:0033059 16 15 0,000 0,01749041 0,03073459 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,01749041 0,0307198 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,01749041 0,03070501 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,01749041 0,03069024 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,01749041 0,03067549 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,01749041 0,03066075 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,01749041 0,03064602 ! ion gated channel activity GO:0022839 17 15 0,000 0,01749041 0,03063131 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,01749041 0,03061661 ! receptor activator activity GO:0030546 17 15 0,000 0,01749041 0,03060193 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,01749041 0,03058726 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,01749041 0,0305726 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,01749041 0,03055796 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,01749041 0,03054333 ! peptide hormone processing GO:0016486 19 15 0,000 0,01749041 0,03052872 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01749041 0,03051412 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,01864599 0,03251462 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01864599 0,03249909 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,01864599 0,03248357 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,01864599 0,03246806 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,01864599 0,03245257 ! kinesin complex GO:0005871 16 16 0,000 0,01864599 0,0324371 ! photoreceptor cell development GO:0042461 22 16 0,000 0,01864599 0,03242163 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,01864599 0,03240619 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,01864599 0,03239076 ! centrosome cycle GO:0007098 26 16 0,000 0,01864599 0,03237534 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,01864599 0,03235994 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,01864599 0,03234455 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,01864599 0,03232918 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,01864599 0,03231382 ! lysosomal transport GO:0007041 16 16 0,000 0,01864599 0,03229848 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,01864599 0,03228315 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,01864599 0,03226783 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,01864599 0,03225253 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,01864599 0,03223725 ! myofibril assembly GO:0030239 17 16 0,000 0,01864599 0,03222197 GO:0055002|striated muscle cell development, ! G1 phase GO:0051318 17 16 0,000 0,01864599 0,03220672 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,01864599 0,03219148 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,01864599 0,03217625 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,01864599 0,03216103 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,01864599 0,03214584 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,01864599 0,03213065 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,01864599 0,03211548 ! steroid catabolic process GO:0006706 18 16 0,000 0,01864599 0,03210033 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,01864599 0,03208518 ! cell-cell recognition GO:0009988 19 16 0,000 0,01864599 0,03207006 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,01864599 0,03205494 ! spleen development GO:0048536 19 16 0,000 0,01864599 0,03203984 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,01864599 0,03202476 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,01864599 0,03200969 ! neural tube closure GO:0001843 19 16 0,000 0,01864599 0,03199463 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,01864599 0,03197959 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,01864599 0,03196456 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,01864599 0,03194955 ! viral genome replication GO:0019079 16 16 0,000 0,01864599 0,03193455 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,01864599 0,03191956 ! memory GO:0007613 18 16 0,000 0,01864599 0,03190459 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,01864599 0,03188963 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01864599 0,03187469 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,01864599 0,03185976 ! glycoprotein binding GO:0001948 19 16 0,000 0,01864599 0,03184485 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,01864599 0,03182994 ! syntaxin binding GO:0019905 18 16 0,000 0,01864599 0,03181506 ! myosin binding GO:0017022 17 16 0,000 0,01864599 0,03180018 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,01864599 0,03178532 ! fucose metabolic process GO:0006004 18 16 0,000 0,01864599 0,03177048 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,01864599 0,03175564 ! membrane budding GO:0006900 18 16 0,000 0,01864599 0,03174083 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,01864599 0,03172602 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,01864599 0,03171123 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,01864599 0,03169645 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,01864599 0,03168169 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,01864599 0,03166694 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,01864599 0,03165221 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,01864599 0,03163748 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,01864599 0,03162277 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,01864599 0,03160808 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,01864599 0,0315934 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01864599 0,03157873 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,01864599 0,03156408 ! axoneme GO:0005930 16 16 0,000 0,01864599 0,03154944 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,01864599 0,03153481 ! anion exchanger activity GO:0015380 17 17 0,000 0,01980028 0,03347147 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,01980028 0,03345597 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,01980028 0,03344048 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,01980028 0,033425 ! glial cell development GO:0021782 17 17 0,000 0,01980028 0,03340954 ! limbic system development GO:0021761 18 17 0,000 0,01980028 0,0333941 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,01980028 0,03337866 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,01980028 0,03336325 ! ephrin receptor activity GO:0005003 21 17 0,000 0,01980028 0,03334784 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,01980028 0,03333245 ! glutamine metabolic process GO:0006541 26 17 0,000 0,01980028 0,03331708 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,01980028 0,03330172 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,01980028 0,03328637 ! signal sequence binding GO:0005048 18 17 0,000 0,01980028 0,03327104 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,01980028 0,03325572 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01980028 0,03324042 ! organelle subcompartment GO:0031984 19 17 0,000 0,01980028 0,03322513 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,01980028 0,03320985 ! membrane depolarization GO:0051899 19 17 0,000 0,01980028 0,03319459 ! oogenesis GO:0048477 20 17 0,000 0,01980028 0,03317934 ! nuclear outer membrane GO:0005640 21 17 0,000 0,01980028 0,03316411 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,01980028 0,03314889 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,01980028 0,03313368 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,01980028 0,03311849 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,01980028 0,03310331 ! organic cation transport GO:0015695 17 17 0,000 0,01980028 0,03308815 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,01980028 0,033073 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,01980028 0,03305786 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,01980028 0,03304274 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,01980028 0,03302763 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,01980028 0,03301254 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,01980028 0,03299745 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,01980028 0,03298239 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,01980028 0,03296733 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01980028 0,03295229 ! lipid localization GO:0010876 19 17 0,000 0,01980028 0,03293727 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,01980028 0,03292226 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,01980028 0,03290726 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,01980028 0,03289227 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,01980028 0,0328773 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,01980028 0,03286234 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,01980028 0,0328474 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,01980028 0,03283247 ! response to hexose stimulus GO:0009746 20 17 0,000 0,01980028 0,03281755 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,01980028 0,03280265 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,01980028 0,03278776 ! AMP binding GO:0016208 19 17 0,000 0,01980028 0,03277288 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,01980028 0,03275802 ! receptor metabolic process GO:0043112 20 17 0,000 0,01980028 0,03274317 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,01980028 0,03272833 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,01980028 0,03271351 ! alcohol binding GO:0043178 20 17 0,000 0,01980028 0,0326987 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,01980028 0,0326839 ! visual learning GO:0008542 31 17 0,000 0,01980028 0,03266912 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,01980028 0,03265435 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,01980028 0,0326396 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,01980028 0,03262485 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,01980028 0,03261013 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,01980028 0,03259541 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,01980028 0,03258071 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,01980028 0,03256602 ! translation elongation factor activity GO:0003746 19 17 0,000 0,01980028 0,03255134 ! histone binding GO:0042393 26 17 0,000 0,01980028 0,03253668 ! cilium assembly GO:0042384 18 17 0,000 0,01980028 0,03252203 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,01980028 0,03250739 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,01980028 0,03249277 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,01980028 0,03247816 ! protein secretion GO:0009306 19 18 0,000 0,02095327 0,03435395 ! positive regulation of ossification GO:0045778 19 18 0,000 0,02095327 0,03433852 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,02095327 0,0343231 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,02095327 0,03430769 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,02095327 0,0342923 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,02095327 0,03427692 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,02095327 0,03426156 ! cAMP metabolic process GO:0046058 18 18 0,000 0,02095327 0,03424621 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,02095327 0,03423087 ! cornified envelope GO:0001533 22 18 0,000 0,02095327 0,03421555 ! retinoid metabolic process GO:0001523 19 18 0,000 0,02095327 0,03420024 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,02095327 0,03418495 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,02095327 0,03416966 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,02095327 0,0341544 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,02095327 0,03413914 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,02095327 0,0341239 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,02095327 0,03410867 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,02095327 0,03409346 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,02095327 0,03407826 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,02095327 0,03406308 ! primary neural tube formation GO:0014020 21 18 0,000 0,02095327 0,0340479 ! recycling endosome GO:0055037 22 18 0,000 0,02095327 0,03403274 ! muscle cell development GO:0055001 20 18 0,000 0,02095327 0,0340176 ! kinase activator activity GO:0019209 22 18 0,000 0,02095327 0,03400246 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,02095327 0,03398735 ! cerebellum development GO:0021549 20 18 0,000 0,02095327 0,03397224 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,02095327 0,03395715 ! somitogenesis GO:0001756 20 18 0,000 0,02095327 0,03394207 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,02095327 0,033927 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,02095327 0,03391195 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,02095327 0,03389691 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,02095327 0,03388189 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,02095327 0,03386688 ! basal plasma membrane GO:0009925 21 18 0,000 0,02095327 0,03385188 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,02095327 0,03383689 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,02095327 0,03382192 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,02095327 0,03380696 ! regulation of cell killing GO:0031341 24 18 0,000 0,02095327 0,03379202 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,02095327 0,03377708 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,02095327 0,03376216 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,02095327 0,03374726 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,02095327 0,03373237 ! protein complex scaffold GO:0032947 22 18 0,000 0,02095327 0,03371749 ! SNAP receptor activity GO:0005484 21 18 0,000 0,02095327 0,03370262 ! dendrite development GO:0016358 22 18 0,000 0,02095327 0,03368777 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,02095327 0,03367293 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,02095327 0,0336581 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,02095327 0,03364328 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,02095327 0,03362848 ! nuclear ubiquitin ligase complex GO:0000152 31 18 0,000 0,02095327 0,03361369 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,02095327 0,03359892 ! coreceptor activity GO:0015026 28 18 0,000 0,02095327 0,03358416 ! response to fungus GO:0009620 18 18 0,000 0,02095327 0,03356941 ! stem cell differentiation GO:0048863 18 18 0,000 0,02095327 0,03355467 ! intermediate filament-based process GO:0045103 18 18 0,000 0,02095327 0,03353995 ! heart process GO:0003015 19 18 0,000 0,02095327 0,03352524 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,02095327 0,03351054 ! vasodilation GO:0042311 20 18 0,000 0,02095327 0,03349585 ! transport vesicle membrane GO:0030658 23 18 0,000 0,02095327 0,03348118 ! MHC protein binding GO:0042287 30 18 0,000 0,02095327 0,03346652 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,02095327 0,03345188 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,02095327 0,03343724 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,02095327 0,03342262 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,02095327 0,03340802 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,02095327 0,03339342 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,02095327 0,03337884 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,02095327 0,03336427 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,02095327 0,03334971 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,02210497 0,03516744 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,02210497 0,03515211 ! proteasome core complex GO:0005839 20 19 0,000 0,02210497 0,03513679 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,02210497 0,03512148 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,02210497 0,03510619 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,02210497 0,03509092 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,02210497 0,03507565 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,02210497 0,0350604 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,02210497 0,03504517 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,02210497 0,03502994 ! lysosome organization GO:0007040 20 19 0,000 0,02210497 0,03501473 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,02210497 0,03499954 ! cellular response to unfolded protein GO:0034620 21 19 0,000 0,02210497 0,03498435 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron development GO:0021954 21 19 0,000 0,02210497 0,03496918 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,02210497 0,03495402 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,02210497 0,03493888 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,02210497 0,03492375 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,02210497 0,03490863 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,02210497 0,03489352 ! peptide cross-linking GO:0018149 23 19 0,000 0,02210497 0,03487843 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,02210497 0,03486335 ! beta-catenin binding GO:0008013 23 19 0,000 0,02210497 0,03484828 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,02210497 0,03483323 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,02210497 0,03481819 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02210497 0,03480316 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,02210497 0,03478815 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,02210497 0,03477315 ! vitamin transport GO:0051180 21 19 0,000 0,02210497 0,03475816 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,02210497 0,03474318 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,02210497 0,03472822 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,02210497 0,03471327 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,02210497 0,03469833 ! retinoid binding GO:0005501 19 19 0,000 0,02210497 0,03468341 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,02210497 0,0346685 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,02210497 0,0346536 ! histone deacetylase activity GO:0004407 20 19 0,000 0,02210497 0,03463872 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,02210497 0,03462384 ! positive regulation of fibroblast proliferation GO:0048146 25 19 0,000 0,02210497 0,03460898 ! gluconeogenesis GO:0006094 23 19 0,000 0,02210497 0,03459414 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,02210497 0,0345793 ! microtubule-based transport GO:0010970 20 19 0,000 0,02210497 0,03456448 ! superoxide metabolic process GO:0006801 21 19 0,000 0,02210497 0,03454967 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,02210497 0,03453487 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02210497 0,03452009 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,02210497 0,03450532 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,02210497 0,03449056 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,02210497 0,03447581 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,02210497 0,03446108 ! acetylcholine binding GO:0042166 20 19 0,000 0,02210497 0,03444636 ! heme metabolic process GO:0042168 20 19 0,000 0,02210497 0,03443165 ! SH2 domain binding GO:0042169 25 19 0,000 0,02210497 0,03441696 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,02210497 0,03440227 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,02210497 0,0343876 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,02210497 0,03437295 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,02210497 0,0343583 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,02210497 0,03434367 ! body fluid secretion GO:0007589 21 19 0,000 0,02210497 0,03432905 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,02210497 0,03431444 ! secretory granule membrane GO:0030667 21 19 0,000 0,02210497 0,03429984 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,02210497 0,03428526 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,02210497 0,03427069 ! peptidase activator activity GO:0016504 21 19 0,000 0,02210497 0,03425613 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02210497 0,03424158 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,02210497 0,03422705 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,02210497 0,03421253 ! sialyltransferase activity GO:0008373 31 19 0,000 0,02210497 0,03419802 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,02210497 0,03418352 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,02325537 0,03594729 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,02325537 0,03593206 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,02325537 0,03591685 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,02325537 0,03590165 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,02325537 0,03588646 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,02325537 0,03587129 ! negative regulation of lipid metabolic process GO:0045833 34 20 0,000 0,02325537 0,03585613 ! ovarian follicle development GO:0001541 21 20 0,000 0,02325537 0,03584098 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 0,000 0,02325537 0,03582584 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,02325537 0,03581072 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,02325537 0,03579561 ! diencephalon development GO:0021536 22 20 0,000 0,02325537 0,03578051 ! regulation of lipid transport GO:0032368 22 20 0,000 0,02325537 0,03576543 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,02325537 0,03575036 ! glutathione metabolic process GO:0006749 21 20 0,000 0,02325537 0,0357353 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,02325537 0,03572025 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,02325537 0,03570522 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,02325537 0,0356902 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,02325537 0,03567519 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,02325537 0,03566019 ! peptide hormone secretion GO:0030072 25 20 0,000 0,02325537 0,03564521 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,02325537 0,03563024 ! Rab GTPase binding GO:0017137 22 20 0,000 0,02325537 0,03561528 ! initiation of viral infection GO:0019059 22 20 0,000 0,02325537 0,03560034 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,02325537 0,0355854 ! heterochromatin GO:0000792 20 20 0,000 0,02325537 0,03557048 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,02325537 0,03555557 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,02325537 0,03554068 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,02325537 0,0355258 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,02325537 0,03551093 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,02325537 0,03549607 ! visual behavior GO:0007632 34 20 0,000 0,02325537 0,03548122 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,02325537 0,03546639 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,02325537 0,03545157 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,02325537 0,03543676 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,02325537 0,03542196 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,02325537 0,03540718 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,02325537 0,03539241 ! rRNA binding GO:0019843 22 20 0,000 0,02325537 0,03537765 ! cytolysis GO:0019835 22 20 0,000 0,02325537 0,0353629 ! renal system process GO:0003014 22 20 0,000 0,02325537 0,03534817 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,02325537 0,03533344 ! fatty acid transport GO:0015908 23 20 0,000 0,02325537 0,03531873 ! transaminase activity GO:0008483 22 20 0,000 0,02325537 0,03530404 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,02325537 0,03528935 ! collagen catabolic process GO:0030574 21 20 0,000 0,02325537 0,03527468 ! microvillus GO:0005902 25 20 0,000 0,02325537 0,03526002 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,02325537 0,03524537 ! connexon complex GO:0005922 23 20 0,000 0,02325537 0,03523073 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,02440448 0,03695623 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,02440448 0,0369409 ! translational initiation GO:0006413 21 21 0,000 0,02440448 0,03692557 ! NF-kappaB binding GO:0051059 31 21 0,000 0,02440448 0,03691026 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,02440448 0,03689497 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,02440448 0,03687968 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,02440448 0,03686441 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,02440448 0,03684915 ! glutathione transferase activity GO:0004364 21 21 0,000 0,02440448 0,03683391 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,02440448 0,03681868 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,02440448 0,03680346 ! regeneration GO:0031099 24 21 0,000 0,02440448 0,03678825 ! MHC class I protein complex GO:0042612 31 21 0,000 0,02440448 0,03677305 ! cellular response to starvation GO:0009267 22 21 0,000 0,02440448 0,03675787 ! peroxisome organization GO:0007031 22 21 0,000 0,02440448 0,0367427 ! vacuole organization GO:0007033 23 21 0,000 0,02440448 0,03672754 ! apoptotic nuclear changes GO:0030262 24 21 0,000 0,02440448 0,0367124 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,02440448 0,03669726 ! neural crest cell development GO:0014032 24 21 0,000 0,02440448 0,03668214 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,02440448 0,03666703 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,02440448 0,03665194 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,02440448 0,03663686 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02440448 0,03662178 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,02440448 0,03660673 ! pallium development GO:0021543 22 21 0,000 0,02440448 0,03659168 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,02440448 0,03657665 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 0,000 0,02440448 0,03656163 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,02440448 0,03654662 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,02440448 0,03653162 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,02440448 0,03651664 ! cyclase activity GO:0009975 22 21 0,000 0,02440448 0,03650166 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,02440448 0,0364867 ! gut development GO:0048565 23 21 0,000 0,02440448 0,03647176 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,02440448 0,03645682 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,02440448 0,0364419 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02440448 0,03642699 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,02440448 0,03641209 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02440448 0,0363972 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,02440448 0,03638233 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,02440448 0,03636747 ! axis specification GO:0009798 25 21 0,000 0,02440448 0,03635262 ! response to alkaloid GO:0043279 27 21 0,000 0,02440448 0,03633778 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,02440448 0,03632295 ! response to ethanol GO:0045471 28 21 0,000 0,02440448 0,03630814 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,02440448 0,03629334 ! smooth muscle contraction GO:0006939 25 21 0,000 0,02440448 0,03627855 ! ubiquitin binding GO:0043130 25 21 0,000 0,02440448 0,03626377 ! vesicle targeting GO:0006903 22 21 0,000 0,02440448 0,03624901 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,02440448 0,03623425 ! SNARE binding GO:0000149 24 21 0,000 0,02440448 0,03621951 ! interaction with host GO:0051701 26 21 0,000 0,02440448 0,03620478 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,02440448 0,03619006 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,02440448 0,03617536 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,02440448 0,03616067 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,02440448 0,03614598 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,02440448 0,03613131 ! cell-cell junction organization GO:0045216 24 21 0,000 0,02440448 0,03611666 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,02440448 0,03610201 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,02440448 0,03608738 ! caveola GO:0005901 25 21 0,000 0,02440448 0,03607275 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,02440448 0,03605814 ! insulin receptor binding GO:0005158 25 21 0,000 0,02440448 0,03604355 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02440448 0,03602896 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02440448 0,03601438 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,02555231 0,03769301 ! metencephalon development GO:0022037 25 22 0,000 0,02555231 0,03767777 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,02555231 0,03766255 ! hormone secretion GO:0046879 28 22 0,000 0,02555231 0,03764734 ! vesicle docking GO:0048278 24 22 0,000 0,02555231 0,03763214 ! muscle myosin complex GO:0005859 23 22 0,000 0,02555231 0,03761695 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,02555231 0,03760178 ! actomyosin structure organization GO:0031032 24 22 0,000 0,02555231 0,03758662 ! microtubule organizing center organization GO:0031023 33 22 0,000 0,02555231 0,03757147 GO:0051297|centrosome organization, ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,02555231 0,03755633 ! sperm motility GO:0030317 23 22 0,000 0,02555231 0,0375412 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,02555231 0,03752609 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,02555231 0,03751099 ! vacuolar transport GO:0007034 22 22 0,000 0,02555231 0,0374959 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,02555231 0,03748082 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,02555231 0,03746576 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,02555231 0,03745071 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,02555231 0,03743567 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,02555231 0,03742064 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,02555231 0,03740562 ! PML body GO:0016605 25 22 0,000 0,02555231 0,03739062 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,02555231 0,03737563 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,02555231 0,03736064 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,02555231 0,03734568 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,02555231 0,03733072 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,02555231 0,03731578 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,02555231 0,03730084 ! deacetylase activity GO:0019213 23 22 0,000 0,02555231 0,03728592 ! pentose metabolic process GO:0019321 23 22 0,000 0,02555231 0,03727102 ! collagen fibril organization GO:0030199 32 22 0,000 0,02555231 0,03725612 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,02555231 0,03724123 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,02555231 0,03722636 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,02555231 0,0372115 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,02555231 0,03719665 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! positive regulation of B cell activation GO:0050871 26 22 0,000 0,02555231 0,03718181 ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,02555231 0,03716699 ! positive regulation of behavior GO:0048520 24 22 0,000 0,02555231 0,03715218 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,02555231 0,03713737 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,02555231 0,03712258 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,02555231 0,03710781 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,02555231 0,03709304 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,02555231 0,03707829 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,02555231 0,03706354 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,02555231 0,03704881 ! glycerol metabolic process GO:0006071 24 22 0,000 0,02555231 0,03703409 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,02555231 0,03701938 ! nuclear chromatin GO:0000790 23 22 0,000 0,02555231 0,03700469 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,02555231 0,03699 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,02555231 0,03697533 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,02555231 0,03696067 ! sterol binding GO:0032934 24 22 0,000 0,02555231 0,03694602 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,02555231 0,03693138 ! digestive system process GO:0022600 25 22 0,000 0,02555231 0,03691676 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,02555231 0,03690214 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,02555231 0,03688754 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,02555231 0,03687295 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,02555231 0,03685837 ! base-excision repair GO:0006284 33 22 0,000 0,02555231 0,0368438 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,02555231 0,03682924 ! DNA modification GO:0006304 25 22 0,000 0,02555231 0,0368147 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,02555231 0,03680016 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,02555231 0,03678564 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,02555231 0,03677113 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,02555231 0,03675663 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,02555231 0,03674214 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,02555231 0,03672766 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,02555231 0,0367132 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,02555231 0,03669874 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,02669884 0,03833033 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,02669884 0,03831525 ! leukocyte adhesion GO:0007159 26 23 0,000 0,02669884 0,03830018 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,02669884 0,03828512 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,02669884 0,03827008 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,02669884 0,03825505 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,02669884 0,03824003 ! ureteric bud development GO:0001657 24 23 0,000 0,02669884 0,03822502 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,02669884 0,03821003 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,02669884 0,03819504 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,02669884 0,03818007 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,02669884 0,03816511 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,02669884 0,03815016 ! deaminase activity GO:0019239 24 23 0,000 0,02669884 0,03813522 ! sensory perception of pain GO:0019233 26 23 0,000 0,02669884 0,0381203 ! lipid kinase activity GO:0001727 26 23 0,000 0,02669884 0,03810538 ! platelet activation GO:0030168 27 23 0,000 0,02669884 0,03809048 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,02669884 0,03807559 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,02669884 0,03806071 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,02669884 0,03804584 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,02669884 0,03803099 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,02669884 0,03801614 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,02669884 0,03800131 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,02669884 0,03798649 ! cell surface binding GO:0043498 28 23 0,000 0,02669884 0,03797168 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,02669884 0,03795688 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,02669884 0,03794209 ! regulation of glucose import GO:0046324 28 23 0,000 0,02669884 0,03792732 ! alditol metabolic process GO:0019400 25 23 0,000 0,02669884 0,03791256 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,02669884 0,0378978 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,02669884 0,03788306 ! zinc ion transport GO:0006829 26 23 0,000 0,02669884 0,03786833 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,02669884 0,03785362 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,02669884 0,03783891 ! sex determination GO:0007530 25 23 0,000 0,02669884 0,03782422 ! phosphate binding GO:0042301 25 23 0,000 0,02669884 0,03780953 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,02669884 0,03779486 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,02669884 0,0377802 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,02669884 0,03776555 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,02669884 0,03775091 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,02669884 0,03773629 ! positive regulation of nuclear division GO:0051785 35 23 0,000 0,02669884 0,03772167 GO:0045840|positive regulation of mitosis, ! synaptogenesis GO:0007416 25 23 0,000 0,02669884 0,03770707 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,02669884 0,03769248 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,02669884 0,03767789 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,02669884 0,03766332 ! leukocyte proliferation GO:0070661 26 23 0,000 0,02669884 0,03764877 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,02669884 0,03763422 ! growth cone GO:0030426 27 24 0,000 0,02784408 0,03923337 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,02784408 0,03921823 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02784408 0,03920309 ! pancreas development GO:0031016 27 24 0,000 0,02784408 0,03918797 ! androgen receptor binding GO:0050681 34 24 0,000 0,02784408 0,03917285 ! calcium channel complex GO:0034704 31 24 0,000 0,02784408 0,03915775 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,02784408 0,03914266 ! negative regulation of cell development GO:0010721 30 24 0,000 0,02784408 0,03912758 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,02784408 0,03911252 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,02784408 0,03909746 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,02784408 0,03908242 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,02784408 0,03906739 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,02784408 0,03905237 ! Rho GTPase binding GO:0017048 36 24 0,000 0,02784408 0,03903736 ! regulation of glucose transport GO:0010827 29 24 0,000 0,02784408 0,03902236 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,02784408 0,03900738 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,02784408 0,0389924 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,02784408 0,03897744 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,02784408 0,03896249 ! protein stabilization GO:0050821 24 24 0,000 0,02784408 0,03894755 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,02784408 0,03893262 ! embryonic pattern specification GO:0009880 29 24 0,000 0,02784408 0,0389177 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,02784408 0,0389028 ! RNA polymerase complex GO:0030880 25 24 0,000 0,02784408 0,0388879 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,02784408 0,03887302 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,02784408 0,03885815 ! small conjugating protein binding GO:0032182 29 24 0,000 0,02784408 0,03884329 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,02784408 0,03882844 ! chemokine binding GO:0019956 26 24 0,000 0,02784408 0,03881361 ! catechol metabolic process GO:0009712 29 24 0,000 0,02784408 0,03879878 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,02784408 0,03878397 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,02784408 0,03876916 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,02784408 0,03875437 ! cell aging GO:0007569 47 24 0,000 0,02784408 0,03873959 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,02784408 0,03872482 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,02784408 0,03871006 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,02784408 0,03869532 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,02784408 0,03868058 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,02784408 0,03866586 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,02784408 0,03865114 ! caspase regulator activity GO:0043028 26 24 0,000 0,02784408 0,03863644 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 0,000 0,02784408 0,03862175 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,02784408 0,03860707 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,02784408 0,0385924 ! selenium binding GO:0008430 24 24 0,000 0,02784408 0,03857775 ! spindle pole GO:0000922 35 24 0,000 0,02784408 0,0385631 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,02784408 0,03854847 ! site of polarized growth GO:0030427 28 25 0,000 0,02898804 0,04011698 ! phenol metabolic process GO:0018958 31 25 0,000 0,02898804 0,04010177 ! regulation of lipid biosynthetic process GO:0046890 35 25 0,000 0,02898804 0,04008657 ! protein amino acid acylation GO:0043543 28 25 0,000 0,02898804 0,04007138 ! aromatase activity GO:0070330 28 25 0,000 0,02898804 0,0400562 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,02898804 0,04004103 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,02898804 0,04002588 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,02898804 0,04001073 ! response to starvation GO:0042594 26 25 0,000 0,02898804 0,0399956 ! dynein complex GO:0030286 28 25 0,000 0,02898804 0,03998048 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,02898804 0,03996537 ! regulation of behavior GO:0050795 27 25 0,000 0,02898804 0,03995027 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,02898804 0,03993518 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,02898804 0,03992011 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,02898804 0,03990504 ! hormone transport GO:0009914 31 25 0,000 0,02898804 0,03988999 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,02898804 0,03987495 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,02898804 0,03985992 ! regulation of coagulation GO:0050818 28 25 0,000 0,02898804 0,0398449 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,02898804 0,03982989 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,02898804 0,0398149 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,02898804 0,03979991 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,02898804 0,03978494 ! molting cycle process GO:0022404 28 25 0,000 0,02898804 0,03976997 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,02898804 0,03975502 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,02898804 0,03974008 ! phototransduction GO:0007602 27 25 0,000 0,02898804 0,03972516 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,02898804 0,03971024 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,02898804 0,03969533 ! protein phosphatase binding GO:0019903 27 25 0,000 0,02898804 0,03968044 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,02898804 0,03966555 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,02898804 0,03965068 ! autophagy GO:0006914 28 25 0,000 0,02898804 0,03963582 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,02898804 0,03962097 ! response to ionizing radiation GO:0010212 37 25 0,000 0,02898804 0,03960613 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,02898804 0,0395913 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,03013071 0,04113654 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,03013071 0,04112115 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,03013071 0,04110577 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,03013071 0,0410904 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,03013071 0,04107505 ! hair cycle GO:0042633 29 26 0,000 0,03013071 0,04105971 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,03013071 0,04104437 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,03013071 0,04102905 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,03013071 0,04101374 ! early endosome membrane GO:0031901 31 26 0,000 0,03013071 0,04099845 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,03013071 0,04098316 ! iron ion homeostasis GO:0055072 29 26 0,000 0,03013071 0,04096788 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,03013071 0,04095262 ! GABA receptor activity GO:0016917 31 26 0,000 0,03013071 0,04093737 ! PDZ domain binding GO:0030165 28 26 0,000 0,03013071 0,04092213 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,03013071 0,0409069 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,03013071 0,04089168 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,03013071 0,04087647 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,03013071 0,04086128 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,03013071 0,04084609 ! fatty acid binding GO:0005504 28 26 0,000 0,03013071 0,04083092 ! blastocyst development GO:0001824 27 26 0,000 0,03013071 0,04081576 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,03013071 0,04080061 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,03013071 0,04078547 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,03013071 0,04077034 ! regulation of fibroblast proliferation GO:0048145 32 26 0,000 0,03013071 0,04075522 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,03013071 0,04074012 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,03013071 0,04072502 ! iron ion transport GO:0006826 33 26 0,000 0,03013071 0,04070994 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,03013071 0,04069487 ! glucose transport GO:0015758 27 26 0,000 0,03013071 0,0406798 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,03013071 0,04066475 ! spinal cord development GO:0021510 30 26 0,000 0,03013071 0,04064972 ! histone deacetylase complex GO:0000118 29 26 0,000 0,03013071 0,04063469 ! response to endoplasmic reticulum stress GO:0034976 30 26 0,000 0,03013071 0,04061967 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,03013071 0,04060467 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,03013071 0,04058967 ! RNA helicase activity GO:0003724 46 26 0,000 0,03013071 0,04057469 ! brush border GO:0005903 30 26 0,000 0,03013071 0,04055972 ! gap junction GO:0005921 29 26 0,000 0,03013071 0,04054476 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,03013071 0,04052981 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,0312721 0,04204962 ! mRNA catabolic process GO:0006402 31 27 0,000 0,0312721 0,04203413 ! myelination GO:0042552 31 27 0,000 0,0312721 0,04201864 ! trans-Golgi network GO:0005802 31 27 0,000 0,0312721 0,04200317 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,0312721 0,04198771 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,0312721 0,04197227 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,0312721 0,04195683 ! vasculogenesis GO:0001570 32 27 0,000 0,0312721 0,0419414 ! hexose transport GO:0008645 28 27 0,000 0,0312721 0,04192599 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,0312721 0,04191059 ! spindle organization GO:0007051 38 27 0,000 0,0312721 0,0418952 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,0312721 0,04187982 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,0312721 0,04186445 ! cell fate determination GO:0001709 29 27 0,000 0,0312721 0,04184909 ! lipid oxidation GO:0034440 29 27 0,000 0,0312721 0,04183374 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,0312721 0,04181841 ! collagen binding GO:0005518 29 27 0,000 0,0312721 0,04180309 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,0312721 0,04178777 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,0312721 0,04177247 ! liver development GO:0001889 33 27 0,000 0,0312721 0,04175718 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,0312721 0,0417419 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,0312721 0,04172663 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,0312721 0,04171138 ! membrane docking GO:0022406 29 27 0,000 0,0312721 0,04169613 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,0312721 0,0416809 GO:0050908|detection of light stimulus involved in visual perception, ! fat cell differentiation GO:0045444 30 27 0,000 0,0312721 0,04166568 ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,0312721 0,04165046 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,0312721 0,04163526 ! phospholipid transport GO:0015914 29 27 0,000 0,0312721 0,04162007 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,0312721 0,04160489 ! aminopeptidase activity GO:0004177 33 27 0,000 0,0312721 0,04158973 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,0312721 0,04157457 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,0312721 0,04155942 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,0312721 0,04154429 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,0312721 0,04152917 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,0312721 0,04151405 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,03241221 0,04301191 ! Golgi stack GO:0005795 30 28 0,000 0,03241221 0,04299626 ! male gonad development GO:0008584 32 28 0,000 0,03241221 0,04298064 ! regulation of fatty acid metabolic process GO:0019217 41 28 0,000 0,03241221 0,04296502 ! lipoprotein binding GO:0008034 31 28 0,000 0,03241221 0,04294941 ! mesoderm formation GO:0001707 34 28 0,000 0,03241221 0,04293382 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,03241221 0,04291823 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,03241221 0,04290266 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,03241221 0,0428871 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,03241221 0,04287155 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,03241221 0,04285601 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,03241221 0,04284048 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,03241221 0,04282497 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,03241221 0,04280946 ! tissue homeostasis GO:0001894 31 28 0,000 0,03241221 0,04279397 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,03241221 0,04277848 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,03241221 0,04276301 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,03241221 0,04274755 ! sister chromatid segregation GO:0000819 49 28 0,000 0,03241221 0,0427321 ! post-embryonic development GO:0009791 32 28 0,000 0,03241221 0,04271666 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,03241221 0,04270124 ! negative regulation of phosphorylation GO:0042326 30 28 0,000 0,03241221 0,04268582 ! detection of visible light GO:0009584 30 28 0,000 0,03241221 0,04267042 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,03241221 0,04265502 ! receptor regulator activity GO:0030545 31 28 0,000 0,03241221 0,04263964 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,03241221 0,04262427 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,03241221 0,04260891 ! response to heat GO:0009408 33 28 0,000 0,03241221 0,04259356 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,03241221 0,04257822 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,03355103 0,04405837 ! hormone binding GO:0042562 31 29 0,000 0,03355103 0,04404252 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,03355103 0,04402668 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,03355103 0,04401085 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,03355103 0,04399503 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,03355103 0,04397922 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,03355103 0,04396342 ! erythrocyte differentiation GO:0030218 35 29 0,000 0,03355103 0,04394764 ! ceramide metabolic process GO:0006672 29 29 0,000 0,03355103 0,04393186 ! replication fork GO:0005657 42 29 0,000 0,03355103 0,0439161 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,03355103 0,04390035 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,03355103 0,04388461 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,03355103 0,04386888 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,03355103 0,04385316 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,03355103 0,04383745 ! regulation of pH GO:0006885 30 29 0,000 0,03355103 0,04382176 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,03355103 0,04380607 ! ER-nuclear signaling pathway GO:0006984 32 29 0,000 0,03355103 0,0437904 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,03355103 0,04377474 ! phospholipase C activity GO:0004629 43 29 0,000 0,03355103 0,04375909 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,03355103 0,04374345 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,03355103 0,04372782 ! sodium channel activity GO:0005272 33 29 0,000 0,03355103 0,0437122 ! sarcoplasm GO:0016528 31 29 0,000 0,03355103 0,0436966 ! detection of light stimulus GO:0009583 31 29 0,000 0,03355103 0,043681 ! spermatid development GO:0007286 30 29 0,000 0,03355103 0,04366542 ! DNA polymerase activity GO:0034061 34 29 0,000 0,03355103 0,04364984 ! sarcolemma GO:0042383 30 29 0,000 0,03355103 0,04363428 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,03355103 0,04361873 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,03355103 0,04360319 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,03355103 0,04358767 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,03468858 0,04504946 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,03468858 0,04503343 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,03468858 0,04501741 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,03468858 0,0450014 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,03468858 0,0449854 ! scavenger receptor activity GO:0005044 39 30 0,000 0,03468858 0,04496942 ! spliceosome assembly GO:0000245 34 30 0,000 0,03468858 0,04495344 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,03468858 0,04493748 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,03468858 0,04492152 ! metanephros development GO:0001656 31 30 0,000 0,03468858 0,04490558 ! glutamate receptor activity GO:0008066 35 30 0,000 0,03468858 0,04488965 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,03468858 0,04487374 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,03468858 0,04485783 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,03468858 0,04484193 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,03468858 0,04482605 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,03468858 0,04481017 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,03468858 0,04479431 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,03468858 0,04477846 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,03468858 0,04476262 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,03468858 0,04474679 ! protein-lipid complex GO:0032994 41 30 0,000 0,03468858 0,04473098 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,03468858 0,04471517 ! phosphatase binding GO:0019902 34 30 0,000 0,03468858 0,04469938 ! acute-phase response GO:0006953 44 30 0,000 0,03468858 0,04468359 ! segmentation GO:0035282 37 30 0,000 0,03468858 0,04466782 ! response to toxin GO:0009636 33 30 0,000 0,03468858 0,04465206 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,03468858 0,04463631 ! antigen binding GO:0003823 33 30 0,000 0,03468858 0,04462057 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,03468858 0,04460484 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,03468858 0,04458912 ! ensheathment of neurons GO:0007272 35 30 0,000 0,03468858 0,04457342 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,03468858 0,04455772 ! regulation of microtubule-based process GO:0032886 41 30 0,000 0,03468858 0,04454204 ! vesicle localization GO:0051648 31 30 0,000 0,03468858 0,04452637 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,03582485 0,04596871 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03582485 0,04595255 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 0,000 0,03582485 0,04593639 GO:0045936|negative regulation of phosphate metabolic process, ! acrosomal vesicle GO:0001669 34 31 0,000 0,03582485 0,04592025 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03582485 0,04590412 ! protein targeting to membrane GO:0006612 35 31 0,000 0,03582485 0,04588801 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,03582485 0,0458719 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,03582485 0,0458558 ! formation of primary germ layer GO:0001704 37 31 0,000 0,03582485 0,04583972 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,03582485 0,04582365 ! endocytic vesicle GO:0030139 33 31 0,000 0,03582485 0,04580758 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,03582485 0,04579153 ! spermatid differentiation GO:0048515 32 31 0,000 0,03582485 0,0457755 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,03582485 0,04575947 ! neuron fate commitment GO:0048663 44 31 0,000 0,03582485 0,04574345 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,03582485 0,04572745 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,03582485 0,04571145 ! response to calcium ion GO:0051592 34 31 0,000 0,03582485 0,04569547 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,03582485 0,0456795 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,03582485 0,04566354 ! cell junction assembly GO:0034329 36 31 0,000 0,03582485 0,04564759 ! drug binding GO:0008144 34 31 0,000 0,03582485 0,04563165 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,03582485 0,04561572 ! peptide transport GO:0015833 36 31 0,000 0,03582485 0,0455998 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,03582485 0,0455839 ! peripheral nervous system development GO:0007422 35 31 0,000 0,03582485 0,04556801 ! I band GO:0031674 34 31 0,000 0,03582485 0,04555212 ! BMP signaling pathway GO:0030509 33 31 0,000 0,03582485 0,04553625 ! adult locomotory behavior GO:0008344 37 31 0,000 0,03582485 0,04552039 ! gene silencing GO:0016458 33 31 0,000 0,03582485 0,04550454 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,03695984 0,04692986 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,03695984 0,04691353 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,03695984 0,04689721 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,03695984 0,04688091 ! meiosis I GO:0007127 53 32 0,000 0,03695984 0,04686461 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,03695984 0,04684833 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,03695984 0,04683206 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,03695984 0,04681579 ! vesicle coat GO:0030120 39 32 0,000 0,03695984 0,04679954 ! cytokine production GO:0001816 32 32 0,000 0,03695984 0,04678331 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,03695984 0,04676708 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,03695984 0,04675086 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,03695984 0,04673466 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,03695984 0,04671846 ! oxygen binding GO:0019825 33 32 0,000 0,03695984 0,04670228 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,03695984 0,04668611 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,03695984 0,04666995 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,03695984 0,0466538 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,03695984 0,04663766 ! microtubule organizing center part GO:0044450 46 32 0,000 0,03695984 0,04662154 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,03809355 0,04803501 ! DNA helicase activity GO:0003678 55 33 0,000 0,03809355 0,04801841 ! neural tube development GO:0021915 37 33 0,000 0,03809355 0,04800183 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,03809355 0,04798525 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,03809355 0,04796869 ! organelle envelope lumen GO:0031970 46 33 0,000 0,03809355 0,04795213 ! regulation of cellular ketone metabolic process GO:0010565 46 33 0,000 0,03809355 0,04793559 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,03809355 0,04791906 ! NAD or NADH binding GO:0051287 36 33 0,000 0,03809355 0,04790255 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,03809355 0,04788604 ! B cell differentiation GO:0030183 37 33 0,000 0,03809355 0,04786954 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 0,000 0,03809355 0,04785306 ! aerobic respiration GO:0009060 35 33 0,000 0,03809355 0,04783659 ! embryonic organ development GO:0048568 41 33 0,000 0,03809355 0,04782013 ! placenta development GO:0001890 39 33 0,000 0,03809355 0,04780368 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,03809355 0,04778724 ! tissue remodeling GO:0048771 37 33 0,000 0,03809355 0,04777081 ! flagellum GO:0019861 34 33 0,000 0,03809355 0,04775439 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,03809355 0,04773799 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03809355 0,04772159 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,03809355 0,04770521 ! odontogenesis GO:0042476 39 34 0,000 0,039226 0,04910653 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,039226 0,04908969 ! lipid homeostasis GO:0055088 37 34 0,000 0,039226 0,04907285 ! telencephalon development GO:0021537 36 34 0,000 0,039226 0,04905603 ! clathrin coat GO:0030118 41 34 0,000 0,039226 0,04903922 ! cell growth GO:0016049 36 34 0,000 0,039226 0,04902242 ! regulation of B cell activation GO:0050864 40 34 0,000 0,039226 0,04900563 ! protein polymerization GO:0051258 38 34 0,000 0,039226 0,04898885 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,039226 0,04897208 ! learning GO:0007612 51 34 0,000 0,039226 0,04895533 ! keratinization GO:0031424 40 34 0,000 0,039226 0,04893859 ! ovulation cycle process GO:0022602 35 34 0,000 0,039226 0,04892186 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,039226 0,04890514 ! steroid hormone receptor binding GO:0035258 44 34 0,000 0,039226 0,04888843 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,039226 0,04887173 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,039226 0,04885505 ! regulation of protein stability GO:0031647 35 34 0,000 0,039226 0,04883837 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,039226 0,04882171 ! glycogen metabolic process GO:0005977 48 34 0,000 0,039226 0,04880506 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,039226 0,04878842 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,039226 0,04877179 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,039226 0,04875517 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,04035716 0,05014405 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 53 35 0,000 0,04035716 0,05012698 ! response to estrogen stimulus GO:0043627 48 35 0,000 0,04035716 0,05010992 ! inner ear morphogenesis GO:0042472 46 35 0,000 0,04035716 0,05009287 ! MHC protein complex GO:0042611 50 35 0,000 0,04035716 0,05007583 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,04035716 0,0500588 ! vesicle lumen GO:0031983 38 35 0,000 0,04035716 0,05004179 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,04035716 0,05002478 ! mesenchymal cell development GO:0014031 40 35 0,000 0,04035716 0,05000779 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,04035716 0,04999081 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,04035716 0,04997384 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,04035716 0,04995688 ! regulation of proteolysis GO:0030162 37 35 0,000 0,04035716 0,04993994 ! ovulation cycle GO:0042698 37 35 0,000 0,04035716 0,049923 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,04035716 0,04990608 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,04035716 0,04988917 ! collagen GO:0005581 54 35 0,000 0,04035716 0,04987227 ! glucan metabolic process GO:0044042 49 35 0,000 0,04035716 0,04985538 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,04035716 0,0498385 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,04035716 0,04982164 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,04035716 0,04980478 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,04035716 0,04978794 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,04035716 0,04977111 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,04035716 0,04975429 ! maintenance of protein location GO:0045185 45 35 0,000 0,04035716 0,04973748 ! polyol metabolic process GO:0019751 46 35 0,000 0,04035716 0,04972068 ! androgen receptor signaling pathway GO:0030521 47 35 0,000 0,04035716 0,0497039 ! cytokinesis GO:0000910 38 35 0,000 0,04035716 0,04968712 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,04035716 0,04967036 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,04148706 0,05104378 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,04148706 0,05102657 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,04148706 0,05100937 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,04148706 0,05099219 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,04148706 0,05097501 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,04148706 0,05095785 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,04148706 0,0509407 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,04148706 0,05092355 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,04148706 0,05090643 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,04148706 0,05088931 ! nucleus organization GO:0006997 42 36 0,000 0,04148706 0,0508722 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 0,000 0,04148706 0,05085511 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,04148706 0,05083803 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,04148706 0,05082096 ! cellular response to extracellular stimulus GO:0031668 37 36 0,000 0,04148706 0,0508039 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,04148706 0,05078685 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,04148706 0,05076981 ! positive regulation of mast cell proliferation GO:0070668 43 36 0,000 0,04148706 0,05075279 GO:0050671|positive regulation of lymphocyte proliferation, ! maintenance of location in cell GO:0051651 38 36 0,000 0,04148706 0,05073577 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,04261569 0,05209854 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,04261569 0,05208109 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,04261569 0,05206364 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,04261569 0,05204621 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,04261569 0,0520288 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,04261569 0,05201139 ! endoribonuclease activity GO:0004521 48 37 0,000 0,04261569 0,05199399 ! hindbrain development GO:0030902 43 37 0,000 0,04261569 0,05197661 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,04261569 0,05195924 ! pigmentation GO:0043473 51 37 0,000 0,04261569 0,05194188 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,04261569 0,05192453 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,04261569 0,05190719 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,04261569 0,05188987 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,04261569 0,05187255 ! sensory perception of taste GO:0050909 37 37 0,000 0,04261569 0,05185525 ! cell junction organization GO:0034330 44 37 0,000 0,04261569 0,05183796 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,04261569 0,05182068 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,04261569 0,05180341 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,04261569 0,05178616 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,04261569 0,05176891 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,04261569 0,05175168 ! coated pit GO:0005905 44 37 0,000 0,04261569 0,05173446 ! positive regulation of leukocyte proliferation GO:0070665 47 37 0,000 0,04261569 0,05171725 GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,04374305 0,05306772 ! regulation of translational initiation GO:0006446 50 38 0,000 0,04374305 0,05305008 ! negative regulation of binding GO:0051100 44 38 0,000 0,04374305 0,05303245 ! organic ether metabolic process GO:0018904 50 38 0,000 0,04374305 0,05301483 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,04374305 0,05299723 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,04374305 0,05297963 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,04374305 0,05296205 ! hydro-lyase activity GO:0016836 44 38 0,000 0,04374305 0,05294447 ! synapse organization GO:0050808 43 38 0,000 0,04374305 0,05292691 ! viral infectious cycle GO:0019058 40 38 0,000 0,04374305 0,05290937 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,04374305 0,05289183 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,04374305 0,0528743 ! organic anion transport GO:0015711 42 38 0,000 0,04374305 0,05285679 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,04374305 0,05283929 ! monosaccharide binding GO:0048029 41 38 0,000 0,04374305 0,0528218 ! muscle fiber development GO:0048747 42 38 0,000 0,04374305 0,05280432 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,04374305 0,05278685 ! phagocytosis GO:0006909 44 38 0,000 0,04374305 0,05276939 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,04374305 0,05275195 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,04374305 0,05273452 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,04374305 0,0527171 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,04374305 0,05269969 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,04374305 0,05268229 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,04374305 0,0526649 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,04374305 0,05264752 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,04486914 0,05398504 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,04486914 0,05396724 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,04486914 0,05394945 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,04486914 0,05393167 ! T cell differentiation GO:0030217 64 39 0,000 0,04486914 0,05391391 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,04486914 0,05389616 ! cell fate specification GO:0001708 55 39 0,000 0,04486914 0,05387842 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,04486914 0,05386069 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,04486914 0,05384297 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,04486914 0,05382526 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,04486914 0,05380757 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,04486914 0,05378989 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,04486914 0,05377222 ! amine receptor activity GO:0008227 48 39 0,000 0,04486914 0,05375456 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,04486914 0,05373691 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,04486914 0,05371927 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,04486914 0,05370165 ! double-strand break repair GO:0006302 70 39 0,000 0,04486914 0,05368404 ! pigment metabolic process GO:0042440 43 39 0,000 0,04486914 0,05366644 ! RNA modification GO:0009451 39 39 0,000 0,04486914 0,05364885 ! damaged DNA binding GO:0003684 51 40 0,000 0,04599397 0,05497575 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,04599397 0,05495775 ! peroxisomal membrane GO:0005778 44 40 0,000 0,04599397 0,05493975 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,04599397 0,05492177 ! positive regulation of cell development GO:0010720 43 40 0,000 0,04599397 0,05490379 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,04599397 0,05488583 ! biopolymer methylation GO:0043414 45 40 0,000 0,04599397 0,05486789 ! neuron migration GO:0001764 43 40 0,000 0,04599397 0,05484995 ! regulation of protein secretion GO:0050708 45 40 0,000 0,04599397 0,05483203 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,04599397 0,05481411 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,04599397 0,05479621 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,04599397 0,05477832 ! positive regulation of defense response GO:0031349 41 40 0,000 0,04599397 0,05476044 ! mammary gland development GO:0030879 47 40 0,000 0,04599397 0,05474258 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,04599397 0,05472472 ! neuropeptide binding GO:0042923 42 40 0,000 0,04599397 0,05470688 ! regulation of tube size GO:0035150 44 40 0,000 0,04599397 0,05468905 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,04599397 0,05467123 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,04599397 0,05465342 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,04599397 0,05463562 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,04599397 0,05461784 ! chromatin remodeling GO:0006338 44 40 0,000 0,04599397 0,05460006 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,04599397 0,0545823 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,04711753 0,05589748 ! Notch signaling pathway GO:0007219 46 41 0,000 0,04711753 0,05587931 ! keratin filament GO:0045095 44 41 0,000 0,04711753 0,05586115 ! peptide metabolic process GO:0006518 42 41 0,000 0,04711753 0,055843 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,04711753 0,05582486 ! late endosome membrane GO:0031902 45 41 0,000 0,04711753 0,05580674 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,04711753 0,05578862 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,04711753 0,05577052 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,04711753 0,05575243 ! glycolysis GO:0006096 43 41 0,000 0,04711753 0,05573435 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,04711753 0,05571629 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,04711753 0,05569823 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,04711753 0,05568019 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,04823983 0,05698798 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,04823983 0,05696954 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,04823983 0,0569511 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,04823983 0,05693267 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,04823983 0,05691426 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,04823983 0,05689586 ! developmental growth GO:0048589 45 42 0,000 0,04823983 0,05687747 ! structural constituent of muscle GO:0008307 46 42 0,000 0,04823983 0,05685909 ! mitochondrial transport GO:0006839 45 42 0,000 0,04823983 0,05684073 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,04823983 0,05682237 ! metal cluster binding GO:0051540 47 42 0,000 0,04823983 0,05680403 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,04823983 0,0567857 ! protein serine/threonine phosphatase activity GO:0004722 45 42 0,000 0,04823983 0,05676739 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,04823983 0,05674908 ! positive regulation of cell cycle GO:0045787 56 43 0,000 0,04936087 0,05804914 ! RNA catabolic process GO:0006401 49 43 0,000 0,04936087 0,05803043 ! ear morphogenesis GO:0042471 56 43 0,000 0,04936087 0,05801174 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,04936087 0,05799306 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,04936087 0,05797438 ! cell recognition GO:0008037 51 43 0,000 0,04936087 0,05795572 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,04936087 0,05793708 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 0,000 0,04936087 0,05791844 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,04936087 0,05789982 ! gliogenesis GO:0042063 46 43 0,000 0,04936087 0,05788121 ! endosome transport GO:0016197 48 43 0,000 0,04936087 0,05786261 ! striated muscle contraction GO:0006941 45 43 0,000 0,04936087 0,05784402 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,04936087 0,05782545 ! antioxidant activity GO:0016209 53 43 0,000 0,04936087 0,05780688 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,04936087 0,05778833 ! activation of caspase activity GO:0006919 60 43 0,000 0,04936087 0,05776979 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,04936087 0,05775126 ! histone modification GO:0016570 45 43 0,000 0,04936087 0,05773275 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,04936087 0,05771424 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,05048064 0,05900461 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,05048064 0,05898571 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,05048064 0,05896682 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,05048064 0,05894795 ! chemokine activity GO:0008009 48 44 0,000 0,05048064 0,05892908 ! ruffle GO:0001726 50 44 0,000 0,05048064 0,05891023 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,05048064 0,05889139 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,05048064 0,05887256 ! cartilage development GO:0051216 48 44 0,000 0,05048064 0,05885375 ! membrane fusion GO:0006944 52 44 0,000 0,05048064 0,05883495 ! channel regulator activity GO:0016247 54 44 0,000 0,05048064 0,05881615 ! excretion GO:0007588 53 44 0,000 0,05048064 0,05879738 ! male sex differentiation GO:0046661 52 44 0,000 0,05048064 0,05877861 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,05048064 0,05875985 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,05048064 0,05874111 ! amino acid activation GO:0043038 45 44 0,000 0,05048064 0,05872238 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,05048064 0,05870366 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,05159916 0,05998526 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,05159916 0,05996615 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,05159916 0,05994705 ! organellar ribosome GO:0000313 46 45 0,000 0,05159916 0,05992796 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,05159916 0,05990889 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,05159916 0,05988983 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,05159916 0,05987078 ! transport vesicle GO:0030133 53 45 0,000 0,05159916 0,05985174 ! regulation of endocytosis GO:0030100 52 45 0,000 0,05159916 0,05983272 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,05159916 0,05981371 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,05159916 0,0597947 ! nuclear matrix GO:0016363 56 45 0,000 0,05159916 0,05977572 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,05159916 0,05975674 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,05159916 0,05973778 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,05159916 0,05971882 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,05159916 0,05969988 ! coated vesicle membrane GO:0030662 52 45 0,000 0,05159916 0,05968095 ! covalent chromatin modification GO:0016569 47 45 0,000 0,05159916 0,05966204 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,05159916 0,05964313 ! synaptosome GO:0019717 50 45 0,000 0,05159916 0,05962424 ! chemokine receptor binding GO:0042379 50 45 0,000 0,05159916 0,05960536 ! response to UV GO:0009411 59 45 0,000 0,05159916 0,05958649 ! regulation of action potential GO:0001508 56 46 0,000 0,05271642 0,06085743 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,05271642 0,06083818 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,05271642 0,06081894 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,05271642 0,06079971 ! eye morphogenesis GO:0048592 57 46 0,000 0,05271642 0,0607805 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,05271642 0,06076129 ! methylation GO:0032259 51 46 0,000 0,05271642 0,0607421 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,05271642 0,06072292 ! regulation of ion transport GO:0043269 54 46 0,000 0,05271642 0,06070375 ! leukocyte migration GO:0050900 49 46 0,000 0,05271642 0,0606846 ! neuromuscular process GO:0050905 56 46 0,000 0,05271642 0,06066546 ! sulfotransferase activity GO:0008146 54 46 0,000 0,05271642 0,06064632 ! JNK cascade GO:0007254 48 46 0,000 0,05271642 0,0606272 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,05271642 0,0606081 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,05383242 0,06187167 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,05383242 0,06185218 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,05383242 0,06183271 ! microtubule binding GO:0008017 61 47 0,000 0,05383242 0,06181324 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,05383242 0,06179379 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,05383242 0,06177435 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,05383242 0,06175493 ! viral reproductive process GO:0022415 53 47 0,000 0,05383242 0,06173551 ! RNA elongation GO:0006354 52 47 0,000 0,05383242 0,06171611 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,05383242 0,06169672 ! mRNA binding GO:0003729 65 47 0,000 0,05383242 0,06167735 ! axon GO:0030424 53 48 0,000 0,05494717 0,06293478 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,05494717 0,06291503 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,05494717 0,06289528 ! proteasome complex GO:0000502 50 48 0,000 0,05494717 0,06287556 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,05494717 0,06285584 ! protein homooligomerization GO:0051260 63 48 0,000 0,05494717 0,06283614 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,05494717 0,06281644 ! kinetochore GO:0000776 69 48 0,000 0,05494717 0,06279676 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,05494717 0,0627771 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,05494717 0,06275744 ! growth factor receptor binding GO:0070851 58 48 0,000 0,05494717 0,0627378 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,05494717 0,06271817 ! inner ear development GO:0048839 60 48 0,000 0,05494717 0,06269855 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,05494717 0,06267895 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,05494717 0,06265935 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,05494717 0,06263977 ! B cell mediated immunity GO:0019724 53 48 0,000 0,05494717 0,0626202 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,05494717 0,06260065 ! regulation of cell shape GO:0008360 55 48 0,000 0,05494717 0,0625811 ! establishment of organelle localization GO:0051656 58 48 0,000 0,05494717 0,06256157 ! cell cortex part GO:0044448 54 48 0,000 0,05494717 0,06254205 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,05606066 0,06378955 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,05606066 0,06376966 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,05606066 0,06374978 ! response to temperature stimulus GO:0009266 57 49 0,000 0,05606066 0,06372992 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,05606066 0,06371006 ! lipid modification GO:0030258 55 49 0,000 0,05606066 0,06369022 ! synaptic vesicle GO:0008021 56 49 0,000 0,05606066 0,06367039 ! regulation of gene expression, epigenetic GO:0040029 64 49 0,000 0,05606066 0,06365058 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,05606066 0,06363077 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,05606066 0,06361098 ! maintenance of location GO:0051235 62 49 0,000 0,05606066 0,0635912 ! regulation of actin filament length GO:0030832 62 49 0,000 0,05606066 0,06357143 ! nuclear periphery GO:0034399 60 49 0,000 0,05606066 0,06355168 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,05606066 0,06353194 ! negative regulation of cytoskeleton organization GO:0051494 73 49 0,000 0,05606066 0,0635122 ! nucleotide-excision repair GO:0006289 53 49 0,000 0,05606066 0,06349249 ! regulation of mast cell proliferation GO:0070666 57 49 0,000 0,05606066 0,06347278 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,0571729 0,06471199 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,0571729 0,06469192 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,0571729 0,06467186 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,0571729 0,06465182 ! glucose catabolic process GO:0006007 54 50 0,000 0,0571729 0,06463178 ! aging GO:0007568 92 50 0,000 0,0571729 0,06461176 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,0571729 0,06459175 ! heart morphogenesis GO:0003007 57 50 0,000 0,0571729 0,06457175 ! integrin binding GO:0005178 56 50 0,000 0,0571729 0,06455177 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,0571729 0,06453179 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,0582839 0,06576543 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,0582839 0,0657451 ! regulation of ossification GO:0030278 59 51 0,000 0,0582839 0,06572478 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,0582839 0,06570447 ! positive regulation of organelle organization GO:0010638 69 51 0,000 0,0582839 0,06568417 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,0582839 0,06566388 ! endocrine system development GO:0035270 55 51 0,000 0,0582839 0,06564361 ! germ cell development GO:0007281 56 51 0,000 0,0582839 0,06562335 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,05939364 0,0668522 ! regulation of cellular component size GO:0032535 66 52 0,000 0,05939364 0,06683158 ! carbohydrate transport GO:0008643 57 52 0,000 0,05939364 0,06681097 ! regulation of lymphocyte proliferation GO:0050670 61 52 0,000 0,05939364 0,06679038 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,05939364 0,0667698 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,05939364 0,06674923 ! cell maturation GO:0048469 68 52 0,000 0,05939364 0,06672867 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,05939364 0,06670812 ! vesicle organization GO:0016050 59 52 0,000 0,05939364 0,06668759 ! kidney development GO:0001822 55 52 0,000 0,05939364 0,06666707 ! cellular component disassembly GO:0022411 69 52 0,000 0,05939364 0,06664657 ! cell redox homeostasis GO:0045454 57 52 0,000 0,05939364 0,06662607 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,05939364 0,06660559 ! lipid transporter activity GO:0005319 58 52 0,000 0,05939364 0,06658512 ! cytokine receptor activity GO:0004896 54 52 0,000 0,05939364 0,06656467 ! antiporter activity GO:0015297 53 52 0,000 0,05939364 0,06654422 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,06050213 0,06776536 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,06050213 0,06774456 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,06050213 0,06772377 ! basement membrane GO:0005604 55 53 0,000 0,06050213 0,067703 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,06050213 0,06768223 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,06050213 0,06766149 ! viral reproduction GO:0016032 59 53 0,000 0,06050213 0,06764075 ! chloride transport GO:0006821 60 53 0,000 0,06050213 0,06762003 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,06050213 0,06759932 ! regulation of protein catabolic process GO:0042176 56 53 0,000 0,06050213 0,06757862 ! regulation of DNA replication GO:0006275 75 53 0,000 0,06050213 0,06755793 ! DNA catabolic process GO:0006308 57 53 0,000 0,06050213 0,06753726 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,06050213 0,0675166 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,06050213 0,06749595 ! regulation of leukocyte proliferation GO:0070663 65 53 0,000 0,06050213 0,06747532 GO:0032944|regulation of mononuclear cell proliferation, ! single fertilization GO:0007338 58 53 0,000 0,06050213 0,0674547 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,06160937 0,06866819 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,06160937 0,06864722 ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,06160937 0,06862626 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,06160937 0,06860531 ! coated membrane GO:0048475 65 54 0,000 0,06160937 0,06858438 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,06160937 0,06856345 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,06160937 0,06854254 ! cellular defense response GO:0006968 61 54 0,000 0,06160937 0,06852165 ! gastrulation GO:0007369 62 54 0,000 0,06160937 0,06850076 ! dendrite GO:0030425 60 55 0,000 0,06271537 0,06970923 ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,06271537 0,06968799 ! respiratory chain GO:0070469 57 55 0,000 0,06271537 0,06966677 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,06271537 0,06964557 ! extracellular matrix organization GO:0030198 77 55 0,000 0,06271537 0,06962437 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,06271537 0,06960319 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,06271537 0,06958202 ! translation initiation factor activity GO:0003743 66 55 0,000 0,06271537 0,06956087 ! steroid hormone receptor signaling pathway GO:0030518 70 55 0,000 0,06271537 0,06953972 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,06382013 0,07074319 ! heat shock protein binding GO:0031072 62 56 0,000 0,06382013 0,0707217 ! late endosome GO:0005770 60 56 0,000 0,06382013 0,07070022 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,06382013 0,07067876 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,06382013 0,07065731 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,06382013 0,07063587 ! ribonuclease activity GO:0004540 67 56 0,000 0,06382013 0,07061445 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,06382013 0,07059304 ! mesoderm development GO:0007498 67 56 0,000 0,06382013 0,07057164 ! antigen processing and presentation GO:0019882 73 56 0,000 0,06382013 0,07055025 ! proton transport GO:0015992 59 56 0,000 0,06382013 0,07052888 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,06492364 0,07172667 ! chromosome segregation GO:0007059 92 57 0,000 0,06492364 0,07170495 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,06492364 0,07168325 ! diacylglycerol binding GO:0019992 65 57 0,000 0,06492364 0,07166156 ! B cell activation GO:0042113 63 57 0,000 0,06492364 0,07163988 ! small ribosomal subunit GO:0015935 58 57 0,000 0,06492364 0,07161822 ! detection of external stimulus GO:0009581 64 57 0,000 0,06492364 0,07159657 ! occluding junction GO:0070160 75 58 0,000 0,06602591 0,07279013 GO:0005923|tight junction, ! hydrogen transport GO:0006818 61 58 0,000 0,06602591 0,07276814 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,06602591 0,07274616 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,06602591 0,07272419 ! response to nutrient GO:0007584 68 58 0,000 0,06602591 0,07270224 ! large ribosomal subunit GO:0015934 64 58 0,000 0,06602591 0,07268031 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,06602591 0,07265838 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,06602591 0,07263647 ! myosin complex GO:0016459 64 58 0,000 0,06602591 0,07261457 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,06712694 0,07380322 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,06712694 0,07378099 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,06712694 0,07375876 ! actin filament organization GO:0007015 65 59 0,000 0,06712694 0,07373655 ! regulation of heart contraction GO:0008016 71 59 0,000 0,06712694 0,07371436 ! hexose catabolic process GO:0019320 64 59 0,000 0,06712694 0,07369217 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,06712694 0,07367 ! response to steroid hormone stimulus GO:0048545 74 59 0,000 0,06712694 0,07364785 ! cell projection assembly GO:0030031 79 59 0,000 0,06712694 0,0736257 ! regulation of cellular response to stress GO:0080135 79 59 0,000 0,06712694 0,07360357 ! appendage morphogenesis GO:0035107 68 59 0,000 0,06712694 0,07358146 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,06712694 0,07355935 ! fertilization GO:0009566 65 59 0,000 0,06712694 0,07353726 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,06712694 0,07351519 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,06712694 0,07349312 ! adult behavior GO:0030534 72 59 0,000 0,06712694 0,07347107 ! organelle localization GO:0051640 70 59 0,000 0,06712694 0,07344904 ! positive regulation of secretion GO:0051047 66 60 0,000 0,06822674 0,07463002 ! molecular adaptor activity GO:0060090 73 60 0,000 0,06822674 0,07460765 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,06822674 0,0745853 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,06822674 0,07456295 ! copper ion binding GO:0005507 85 60 0,000 0,06822674 0,07454062 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,06822674 0,0745183 ! activation of immune response GO:0002253 72 60 0,000 0,06822674 0,074496 ! cell cycle checkpoint GO:0000075 91 60 0,000 0,06822674 0,07447371 ! response to metal ion GO:0010038 65 60 0,000 0,06822674 0,07445143 ! appendage development GO:0048736 69 60 0,000 0,06822674 0,07442917 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,06822674 0,07440691 ! secondary metabolic process GO:0019748 67 60 0,000 0,06822674 0,07438468 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,06932529 0,0755598 ! ear development GO:0043583 76 61 0,000 0,06932529 0,07553723 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,06932529 0,07551468 ! learning or memory GO:0007611 79 61 0,000 0,06932529 0,07549214 ! Ras GTPase binding GO:0017016 78 61 0,000 0,06932529 0,07546961 ! camera-type eye development GO:0043010 69 61 0,000 0,06932529 0,07544709 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,06932529 0,07542459 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,07042261 0,07659561 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,07042261 0,07657278 ! lysosomal membrane GO:0005765 69 62 0,000 0,07042261 0,07654996 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,07042261 0,07652716 ! nuclear pore GO:0005643 79 62 0,000 0,07042261 0,07650437 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 0,000 0,07042261 0,07648159 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,07042261 0,07645883 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,07042261 0,07643608 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,07042261 0,07641335 ! chloride channel activity GO:0005254 72 62 0,000 0,07042261 0,07639062 ! cell soma GO:0043025 68 62 0,000 0,07042261 0,07636792 ! microtubule motor activity GO:0003777 94 62 0,000 0,07042261 0,07634522 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 0,000 0,07042261 0,07632254 ! focal adhesion GO:0005925 72 62 0,000 0,07042261 0,07629987 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,07042261 0,07627722 ! negative regulation of cell growth GO:0030308 69 63 0,000 0,07151869 0,07744143 ! FAD binding GO:0050660 71 63 0,000 0,07151869 0,07741845 ! urogenital system development GO:0001655 75 63 0,000 0,07151869 0,07739548 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,07151869 0,07737253 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,07151869 0,07734959 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,07151869 0,07732667 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,07151869 0,07730376 ! regulation of immune effector process GO:0002697 81 63 0,000 0,07151869 0,07728086 ! respiratory tube development GO:0030323 92 64 0,000 0,07261354 0,07844068 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,07261354 0,07841746 ! tRNA processing GO:0008033 73 64 0,000 0,07261354 0,07839425 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,07261354 0,07837106 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,07261354 0,07834788 ! adaptive immune response GO:0002250 70 64 0,000 0,07261354 0,07832471 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,07261354 0,07830156 ! neurotransmitter transport GO:0006836 72 64 0,000 0,07261354 0,07827842 ! response to unfolded protein GO:0006986 66 64 0,000 0,07261354 0,0782553 ! nuclear hormone receptor binding GO:0035257 79 64 0,000 0,07261354 0,07823219 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,07261354 0,07820909 ! negative regulation of cell size GO:0045792 71 65 0,000 0,07370715 0,07936355 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,07370715 0,07934013 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,07370715 0,07931672 ! positive regulation of lymphocyte activation GO:0051251 83 65 0,000 0,07370715 0,07929333 ! response to inorganic substance GO:0010035 71 65 0,000 0,07370715 0,07926996 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,07370715 0,07924659 ! activation of MAPK activity GO:0000187 74 65 0,000 0,07370715 0,07922325 ! gonad development GO:0008406 71 65 0,000 0,07370715 0,07919991 ! acetyltransferase activity GO:0016407 73 65 0,000 0,07370715 0,07917659 ! protein import into nucleus GO:0006606 73 66 0,000 0,07479954 0,08032638 ! developmental maturation GO:0021700 85 66 0,000 0,07479954 0,08030274 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,07479954 0,08027912 ! tubulin binding GO:0015631 92 66 0,000 0,07479954 0,0802555 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,07479954 0,08023191 ! tube morphogenesis GO:0035239 84 66 0,000 0,07479954 0,08020832 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,07479954 0,08018475 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,07479954 0,0801612 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,07589069 0,08130668 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,07589069 0,08128281 ! nuclear import GO:0051170 74 67 0,000 0,07589069 0,08125895 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,07589069 0,08123511 ! chloride ion binding GO:0031404 79 67 0,000 0,07589069 0,08121128 ! humoral immune response GO:0006959 75 67 0,000 0,07589069 0,08118746 ! female pregnancy GO:0007565 78 67 0,000 0,07589069 0,08116366 ! extrinsic to membrane GO:0019898 75 67 0,000 0,07589069 0,08113987 ! anion channel activity GO:0005253 77 67 0,000 0,07589069 0,0811161 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,07589069 0,08109234 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,07698062 0,08223288 ! amine catabolic process GO:0009310 73 68 0,000 0,07698062 0,08220881 ! negative regulation of organelle organization GO:0010639 93 68 0,000 0,07698062 0,08218475 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,07698062 0,08216071 ! cell-substrate junction GO:0030055 78 68 0,000 0,07698062 0,08213668 ! respiratory system development GO:0060541 96 68 0,000 0,07698062 0,08211266 ! mRNA transport GO:0051028 88 69 0,000 0,07806932 0,0832496 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,07806932 0,08322527 ! small GTPase binding GO:0031267 86 69 0,000 0,07806932 0,08320096 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,07806932 0,08317666 ! sarcomere GO:0030017 74 69 0,000 0,07806932 0,08315237 ! exocytosis GO:0006887 76 69 0,000 0,07806932 0,0831281 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,07806932 0,08310385 GO:0060538|skeletal muscle organ development, ! nucleosome assembly GO:0006334 87 69 0,000 0,07806932 0,0830796 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,07806932 0,08305537 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,07806932 0,08303116 ! amine biosynthetic process GO:0009309 78 70 0,000 0,07915679 0,08416321 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,07915679 0,08413869 ! early endosome GO:0005769 104 70 0,000 0,07915679 0,08411418 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,07915679 0,08408969 ! regulation of lipase activity GO:0060191 78 70 0,000 0,07915679 0,08406521 ! amino acid transport GO:0006865 76 70 0,000 0,07915679 0,08404074 ! chromatin assembly GO:0031497 88 70 0,000 0,07915679 0,08401629 ! hormone receptor binding GO:0051427 85 70 0,000 0,07915679 0,08399185 ! positive regulation of phosphorylation GO:0042327 82 70 0,000 0,07915679 0,08396743 ! calcium channel activity GO:0005262 86 70 0,000 0,07915679 0,08394302 ! response to protein stimulus GO:0051789 73 70 0,000 0,07915679 0,08391862 ! axon guidance GO:0007411 87 70 0,000 0,07915679 0,08389424 ! nuclear chromosome part GO:0044454 94 70 0,000 0,07915679 0,08386988 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,08024304 0,08499612 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,08024304 0,08497144 ! protein localization in nucleus GO:0034504 78 71 0,000 0,08024304 0,08494678 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,08024304 0,08492214 ! pore complex GO:0046930 89 72 0,000 0,08132807 0,08604547 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 0,000 0,08132807 0,08602053 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 84 72 0,000 0,08132807 0,08599559 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,08132807 0,08597067 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,08132807 0,08594577 ! regulation of lyase activity GO:0051339 85 72 0,000 0,08132807 0,08592088 ! acute inflammatory response GO:0002526 91 72 0,000 0,08132807 0,085896 ! apical junction complex GO:0043296 90 72 0,000 0,08132807 0,08587114 ! phospholipase activity GO:0004620 99 72 0,000 0,08132807 0,0858463 ! membrane raft GO:0045121 81 72 0,000 0,08132807 0,08582146 ! regulation of neurological system process GO:0031644 91 72 0,000 0,08132807 0,08579664 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,08132807 0,08577184 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,08241187 0,08688974 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,08241187 0,08686464 ! protein transporter activity GO:0008565 80 73 0,000 0,08241187 0,08683955 ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,08241187 0,08681447 ! exopeptidase activity GO:0008238 81 73 0,000 0,08241187 0,08678941 ! digestion GO:0007586 81 73 0,000 0,08241187 0,08676436 ! positive regulation of leukocyte activation GO:0002696 92 73 0,000 0,08241187 0,08673933 ! cell-matrix adhesion GO:0007160 102 74 0,000 0,08349446 0,08785341 ! response to oxygen levels GO:0070482 86 74 0,000 0,08349446 0,08782808 ! potassium channel complex GO:0034705 84 74 0,000 0,08349446 0,08780276 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,08349446 0,08777746 ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,08349446 0,08775217 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,08349446 0,0877269 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,08349446 0,08770164 ! blood coagulation GO:0007596 90 74 0,000 0,08349446 0,08767639 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,08349446 0,08765116 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,08349446 0,08762594 ! phosphoinositide-mediated signaling GO:0048015 92 74 0,000 0,08349446 0,08760074 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,08349446 0,08757555 ! ubiquitin ligase complex GO:0000151 91 74 0,000 0,08349446 0,08755038 ! cell projection part GO:0044463 80 74 0,000 0,08349446 0,08752522 ! meiosis GO:0007126 108 75 0,000 0,08457582 0,08863332 GO:0051327|M phase of meiotic cell cycle, ! regulation of DNA binding GO:0051101 94 75 0,000 0,08457582 0,08860787 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,08457582 0,08858243 ! positive regulation of cell activation GO:0050867 94 75 0,000 0,08457582 0,088557 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,08457582 0,08853159 ! regulation of blood pressure GO:0008217 82 75 0,000 0,08457582 0,0885062 ! transcription initiation GO:0006352 84 75 0,000 0,08457582 0,08848081 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,08457582 0,08845545 ! neuropeptide signaling pathway GO:0007218 85 76 0,000 0,08565597 0,08955946 ! negative regulation of growth GO:0045926 85 76 0,000 0,08565597 0,0895338 ! defense response to bacterium GO:0042742 81 76 0,000 0,08565597 0,08950816 ! regulation of lipid metabolic process GO:0019216 98 76 0,000 0,08565597 0,08948252 ! meiotic cell cycle GO:0051321 109 76 0,000 0,08565597 0,08945691 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,08565597 0,0894313 ! condensed chromosome GO:0000793 106 76 0,000 0,08565597 0,08940571 ! protein-DNA complex GO:0032993 93 76 0,000 0,08565597 0,08938014 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,08565597 0,08935458 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,08565597 0,08932904 ! cytosolic ribosome GO:0022626 82 76 0,000 0,08565597 0,08930351 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,08565597 0,08927799 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,0867349 0,09037672 ! nucleosome organization GO:0034728 96 77 0,000 0,0867349 0,09035092 ! alcohol catabolic process GO:0046164 84 77 0,000 0,0867349 0,09032512 ! vacuolar membrane GO:0005774 86 77 0,000 0,0867349 0,09029935 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,0867349 0,09027358 ! myofibril GO:0030016 82 77 0,000 0,0867349 0,09024783 ! protein oligomerization GO:0051259 93 77 0,000 0,0867349 0,0902221 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,08781261 0,09131711 ! endonuclease activity GO:0004519 111 78 0,000 0,08781261 0,09129108 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,08781261 0,09126507 ! inorganic anion transport GO:0015698 87 78 0,000 0,08781261 0,09123908 ! regulation of protein transport GO:0051223 85 78 0,000 0,08781261 0,0912131 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,08781261 0,09118714 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of protein modification process GO:0031401 100 78 0,000 0,08781261 0,09116119 ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,08781261 0,09113525 ! carboxylesterase activity GO:0004091 93 78 0,000 0,08781261 0,09110933 ! protein ubiquitination GO:0016567 95 78 0,000 0,08781261 0,09108343 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,08781261 0,09105754 ! contractile fiber part GO:0044449 83 78 0,000 0,08781261 0,09103166 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,08888911 0,09212144 ! vitamin metabolic process GO:0006766 86 79 0,000 0,08888911 0,09209528 ! T cell activation GO:0042110 120 79 0,000 0,08888911 0,09206913 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,08888911 0,092043 ! phosphoinositide binding GO:0035091 99 79 0,000 0,08888911 0,09201688 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,0899644 0,09310358 ! eye development GO:0001654 93 80 0,000 0,0899644 0,09307718 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,0899644 0,09305079 ! rhythmic process GO:0048511 90 80 0,000 0,0899644 0,09302441 ! regulation of catabolic process GO:0009894 87 80 0,000 0,0899644 0,09299805 ! SH3 domain binding GO:0017124 95 80 0,000 0,0899644 0,09297171 ! hemostasis GO:0007599 96 80 0,000 0,0899644 0,09294538 ! chromosome, centromeric region GO:0000775 119 80 0,000 0,0899644 0,09291906 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,0899644 0,09289276 ! cell-substrate adhesion GO:0031589 109 80 0,000 0,0899644 0,09286648 ! rRNA processing GO:0006364 84 80 0,000 0,0899644 0,09284021 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,09103848 0,09392205 ! vacuolar part GO:0044437 91 81 0,000 0,09103848 0,09389549 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,09211134 0,09497518 ! forebrain development GO:0030900 93 82 0,000 0,09211134 0,09494834 ! external side of plasma membrane GO:0009897 105 82 0,000 0,09211134 0,09492152 ! cellular respiration GO:0045333 85 82 0,000 0,09211134 0,09489471 ! heparin binding GO:0008201 108 82 0,000 0,09211134 0,09486792 ! microtubule-based movement GO:0007018 119 83 0,000 0,093183 0,09594456 ! nuclear speck GO:0016607 99 83 0,000 0,093183 0,09591749 ! rRNA metabolic process GO:0016072 88 83 0,000 0,093183 0,09589043 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,093183 0,09586339 GO:0070035|purine NTP-dependent helicase activity, ! regulation of T cell activation GO:0050863 104 83 0,000 0,093183 0,09583637 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,093183 0,09580935 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,093183 0,09578236 ! contractile fiber GO:0043292 88 83 0,000 0,093183 0,09575538 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,093183 0,09572841 ! regulation of membrane potential GO:0042391 98 83 0,000 0,093183 0,09570146 ! cilium GO:0005929 88 83 0,000 0,093183 0,09567452 ! regulation of DNA metabolic process GO:0051052 139 84 0,000 0,09425345 0,09674637 ! regulation of defense response GO:0031347 98 84 0,000 0,09425345 0,09671915 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,09425345 0,09669195 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,09425345 0,09666477 ! DNA recombination GO:0006310 147 84 0,000 0,09425345 0,0966376 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,09532269 0,09770643 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,09532269 0,09767899 ! monooxygenase activity GO:0004497 92 85 0,000 0,09532269 0,09765156 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,09532269 0,09762414 ! protein binding, bridging GO:0030674 104 85 0,000 0,09532269 0,09759674 ! negative regulation of transport GO:0051051 98 86 0,000 0,09639073 0,09866257 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,09639073 0,09863489 ! Golgi vesicle transport GO:0048193 98 86 0,000 0,09639073 0,09860723 ! lipase activity GO:0016298 114 86 0,000 0,09639073 0,09857959 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,09639073 0,09855196 ! adherens junction GO:0005912 100 86 0,000 0,09639073 0,09852435 ! microtubule cytoskeleton organization GO:0000226 113 87 0,000 0,09745757 0,09958689 ! leukocyte differentiation GO:0002521 118 87 0,000 0,09745757 0,09955901 ! pigment granule GO:0048770 101 87 0,000 0,09745757 0,09953113 GO:0042470|melanosome, ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,09745757 0,09950328 ! organelle outer membrane GO:0031968 102 88 0,000 0,0985232 0,10056313 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,0985232 0,100535 ! protein processing GO:0016485 100 88 0,000 0,0985232 0,10050689 ! protein tyrosine phosphatase activity GO:0004725 109 89 0,000 0,09958763 0,10156435 ! protein kinase binding GO:0019901 115 89 0,000 0,09958763 0,10153596 ! gland development GO:0048732 108 89 0,000 0,09958763 0,1015076 ! ATP metabolic process GO:0046034 100 90 0,000 0,10065086 0,10256267 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,10065086 0,10253403 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,10065086 0,1025054 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,10065086 0,10247679 ! sterol metabolic process GO:0016125 102 90 0,000 0,10065086 0,1024482 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,10065086 0,10241962 ! anion binding GO:0043168 104 90 0,000 0,10065086 0,10239106 ! amine transport GO:0015837 97 90 0,000 0,10065086 0,10236252 ! response to virus GO:0009615 109 90 0,000 0,10065086 0,10233399 ! outer membrane GO:0019867 104 90 0,000 0,10065086 0,10230548 ! extracellular matrix part GO:0044420 111 90 0,000 0,10065086 0,10227698 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,1017129 0,10332739 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,1017129 0,10329862 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,1017129 0,10326987 ! sulfur metabolic process GO:0006790 98 91 0,000 0,1017129 0,10324114 ! sex differentiation GO:0007548 103 91 0,000 0,1017129 0,10321242 ! hormone metabolic process GO:0042445 107 91 0,000 0,1017129 0,10318372 ! regulation of protein localization GO:0032880 99 91 0,000 0,1017129 0,10315503 ! detection of stimulus GO:0051606 100 91 0,000 0,1017129 0,10312636 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,10277373 0,10417299 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,10277373 0,10414405 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,10277373 0,10411513 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,10277373 0,10408622 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,10277373 0,10405734 ! extracellular structure organization GO:0043062 119 92 0,000 0,10277373 0,10402846 ! cell cycle arrest GO:0007050 103 93 0,000 0,10383337 0,10507189 ! protein import GO:0017038 102 93 0,000 0,10383337 0,10504275 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,10383337 0,10501363 ! response to nutrient levels GO:0031667 105 93 0,000 0,10383337 0,10498452 ! Ras protein signal transduction GO:0007265 118 93 0,000 0,10383337 0,10495543 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,10383337 0,10492636 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,10489182 0,10596659 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,10489182 0,10593725 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,10489182 0,10590793 GO:0060429|epithelium development, ! anchoring junction GO:0070161 108 94 0,000 0,10489182 0,10587863 ! neurotransmitter binding GO:0042165 105 94 0,000 0,10489182 0,10584934 ! DNA packaging GO:0006323 113 94 0,000 0,10489182 0,10582007 ! homophilic cell adhesion GO:0007156 107 95 0,000 0,10594907 0,10685712 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,10594907 0,10682759 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,10594907 0,10679807 ! protein localization in organelle GO:0033365 104 95 0,000 0,10594907 0,10676857 ! immune effector process GO:0002252 110 95 0,000 0,10594907 0,10673908 ! apical plasma membrane GO:0016324 105 95 0,000 0,10594907 0,10670961 ! translational elongation GO:0006414 104 96 0,000 0,10700513 0,10774351 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,10700513 0,10771378 ! in utero embryonic development GO:0001701 110 96 0,000 0,10700513 0,10768406 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,10700513 0,10765436 ! receptor complex GO:0043235 131 96 0,000 0,10700513 0,10762468 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,10700513 0,10759502 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,10700513 0,10756537 ! electron transport chain GO:0022900 104 97 0,000 0,10806 0,10859584 ! microtubule associated complex GO:0005875 135 97 0,000 0,10806 0,10856593 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,10806 0,10853604 ! perinuclear region of cytoplasm GO:0048471 125 97 0,000 0,10806 0,10850616 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,10806 0,1084763 ! protein maturation GO:0051604 109 97 0,000 0,10806 0,10844646 ! intermediate filament GO:0005882 102 98 0,000 0,10911368 0,10947379 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,10911368 0,10944369 ! cell fate commitment GO:0045165 118 98 0,000 0,10911368 0,10941361 ! negative regulation of cellular component organization GO:0051129 132 99 0,000 0,11016617 0,11043864 ! hormone activity GO:0005179 113 99 0,000 0,11016617 0,1104083 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,11016617 0,11037797 ! unfolded protein binding GO:0051082 118 100 0,000 0,11121748 0,1114007 ! nuclear chromosome GO:0000228 127 100 0,000 0,11121748 0,11137012 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,11121748 0,11133956 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 0,000 0,11121748 0,11130901 ! regulation of lymphocyte activation GO:0051249 123 100 0,000 0,11121748 0,11127849 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,11121748 0,11124797 ! response to light stimulus GO:0009416 131 100 0,000 0,11121748 0,11121748