pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/7057-8-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 7 5 2,000 6,703E-08 1,542E-04 GO:0019405|alditol catabolic process, ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 2,000 6,703E-08 7,709E-05 ! positive regulation of endothelial cell migration GO:0010595 18 8 2,000 3,739E-07 2,866E-04 ! cellular carbohydrate catabolic process GO:0044275 13 11 2,000 1,097E-06 6,309E-04 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 2,000 1,461E-06 6,721E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 2,793E-06 1,071E-03 ! fructose metabolic process GO:0006000 20 16 2,000 3,699E-06 1,215E-03 ! regulation of endothelial cell migration GO:0010594 40 19 2,000 6,376E-06 1,833E-03 ! positive regulation of locomotion GO:0040017 35 20 2,000 7,491E-06 1,914E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! alditol metabolic process GO:0019400 24 20 2,000 7,491E-06 1,723E-03 ! regulation of chemotaxis GO:0050920 36 21 2,000 8,728E-06 1,825E-03 ! regulation of behavior GO:0050795 38 22 2,000 1,009E-05 1,934E-03 ! regulation of blood coagulation GO:0030193 34 22 2,000 1,009E-05 1,786E-03 ! regulation of endothelial cell proliferation GO:0001936 46 24 2,000 1,323E-05 2,173E-03 ! sperm motility GO:0030317 27 24 2,000 1,323E-05 2,028E-03 ! regulation of coagulation GO:0050818 39 26 2,000 1,695E-05 2,436E-03 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 2,159E-05 2,922E-03 ! cell cycle arrest GO:0007050 150 86 3,000 2,262E-05 2,89E-03 ! hexose biosynthetic process GO:0019319 35 29 2,000 2,372E-05 2,872E-03 ! monosaccharide biosynthetic process GO:0046364 38 32 2,000 3,208E-05 3,689E-03 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 1,000 3,658E-05 4,006E-03 ! apoptotic cell clearance GO:0043277 13 5 1,000 3,658E-05 3,824E-03 ! positive regulation of blood coagulation GO:0030194 10 5 1,000 3,658E-05 3,658E-03 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 1,000 3,658E-05 3,506E-03 ! polyol metabolic process GO:0019751 44 34 2,000 3,859E-05 3,551E-03 ! alcohol biosynthetic process GO:0046165 45 38 2,000 5,412E-05 4,788E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 5,48E-05 4,668E-03 GO:0046530|photoreceptor cell differentiation, ! negative regulation of focal adhesion formation GO:0051895 16 6 1,000 5,48E-05 4,502E-03 ! regulation of macrophage activation GO:0043030 11 6 1,000 5,48E-05 4,346E-03 ! regulation of Rac protein signal transduction GO:0035020 8 6 1,000 5,48E-05 4,202E-03 ! positive regulation of coagulation GO:0050820 11 6 1,000 5,48E-05 4,066E-03 ! response to calcium ion GO:0051592 58 40 2,000 6,322E-05 4,544E-03 ! positive regulation of response to external stimulus GO:0032103 65 40 2,000 6,322E-05 4,406E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 7,663E-05 5,184E-03 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 1,000 7,663E-05 5,036E-03 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 7,663E-05 4,896E-03 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 7,663E-05 4,764E-03 ! regulation of lipid transport GO:0032368 13 7 1,000 7,663E-05 4,638E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 1,000 7,663E-05 4,519E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 1,000 7,663E-05 4,406E-03 GO:0002688|regulation of leukocyte chemotaxis, ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 7,865E-05 4,412E-03 ! negative regulation of cell migration GO:0030336 92 44 2,000 8,429E-05 4,616E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 1,000 1,02E-04 5,458E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of fibrinolysis GO:0051917 13 8 1,000 1,02E-04 5,334E-03 ! negative regulation of organic acid transport GO:0032891 12 8 1,000 1,02E-04 5,216E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 1,000 1,02E-04 5,102E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 1,000 1,02E-04 4,994E-03 ! substrate-bound cell migration GO:0006929 10 9 1,000 1,31E-04 6,279E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 1,000 1,31E-04 6,151E-03 ! establishment of cell polarity GO:0030010 12 9 1,000 1,31E-04 6,028E-03 ! positive regulation of cell migration GO:0030335 92 51 2,000 1,313E-04 5,922E-03 ! negative regulation of cell motion GO:0051271 104 51 2,000 1,313E-04 5,808E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 1,636E-04 7,1E-03 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 1,636E-04 6,969E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 1,000 1,636E-04 6,842E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 1,636E-04 6,72E-03 ! phagocytosis, engulfment GO:0006911 20 10 1,000 1,636E-04 6,602E-03 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,636E-04 6,488E-03 ! positive regulation of cell motion GO:0051272 99 56 2,000 1,736E-04 6,769E-03 ! Golgi vesicle budding GO:0048194 17 11 1,000 1,997E-04 7,656E-03 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 1,997E-04 7,531E-03 ! regulation of leukocyte migration GO:0002685 24 11 1,000 1,997E-04 7,409E-03 ! regulation of organic acid transport GO:0032890 17 11 1,000 1,997E-04 7,291E-03 ! negative regulation of endothelial cell migration GO:0010596 21 12 1,000 2,394E-04 8,603E-03 ! regulation of interleukin-12 production GO:0032655 16 12 1,000 2,394E-04 8,47E-03 ! response to hexose stimulus GO:0009746 19 13 1,000 2,826E-04 9,847E-03 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 1,000 2,826E-04 9,7E-03 ! regulation of lipid biosynthetic process GO:0046890 16 14 1,000 3,292E-04 0,01113616 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 3,292E-04 0,01097476 ! negative regulation of blood coagulation GO:0030195 19 14 1,000 3,292E-04 0,01081798 ! response to metal ion GO:0010038 103 70 2,000 3,366E-04 0,01090295 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 3,366E-04 0,01075152 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 3,657E-04 0,01152284 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 2,000 3,657E-04 0,01136713 ! response to steroid hormone stimulus GO:0048545 114 73 2,000 3,809E-04 0,01168072 ! response to oxygen levels GO:0070482 137 74 2,000 3,965E-04 0,01199815 ! response to inorganic substance GO:0010035 115 75 2,000 4,124E-04 0,01231941 ! cellular response to unfolded protein GO:0034620 19 16 1,000 4,331E-04 0,01277116 GO:0030968|endoplasmic reticulum unfolded protein response, ! carbohydrate biosynthetic process GO:0016051 97 77 2,000 4,456E-04 0,01297331 ! membrane budding GO:0006900 29 17 1,000 4,903E-04 0,01409493 ! cell-cell junction organization GO:0045216 25 17 1,000 4,903E-04 0,01392092 ! negative regulation of coagulation GO:0050819 23 17 1,000 4,903E-04 0,01375115 ! alcohol catabolic process GO:0046164 104 80 2,000 4,985E-04 0,01381394 ! positive regulation of DNA replication GO:0045740 29 18 1,000 5,509E-04 0,01508331 ! positive regulation of translation GO:0045727 28 18 1,000 5,509E-04 0,01490586 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 5,509E-04 0,01473254 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 1,000 5,509E-04 0,0145632 ! response to carbohydrate stimulus GO:0009743 24 18 1,000 5,509E-04 0,01439771 ! peptide cross-linking GO:0018149 31 18 1,000 5,509E-04 0,01423594 ! visual learning GO:0008542 35 18 1,000 5,509E-04 0,01407776 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 5,953E-04 0,01504661 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 6,149E-04 0,01537317 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 6,149E-04 0,01520787 ! negative regulation of angiogenesis GO:0016525 36 19 1,000 6,149E-04 0,01504608 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 6,16E-04 0,01491423 ! interphase GO:0051325 159 88 2,000 6,588E-04 0,01578357 ! visual behavior GO:0007632 39 21 1,000 7,533E-04 0,01786258 ! cell aging GO:0007569 32 21 1,000 7,533E-04 0,01768031 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 7,533E-04 0,01750172 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 7,533E-04 0,0173267 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 7,533E-04 0,01715515 ! negative regulation of cytokine production GO:0001818 31 21 1,000 7,533E-04 0,01698696 ! carbohydrate catabolic process GO:0016052 121 93 2,000 7,739E-04 0,01728112 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 8,277E-04 0,018304 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 8,277E-04 0,01812967 GO:0010810|regulation of cell-substrate adhesion, ! regulation of response to external stimulus GO:0032101 139 96 2,000 8,487E-04 0,01841564 ! response to light stimulus GO:0009416 153 96 2,000 8,487E-04 0,01824353 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 9,054E-04 0,01928124 ! osteoblast differentiation GO:0001649 40 23 1,000 9,054E-04 0,01910435 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 9,054E-04 0,01893067 ! Ras protein signal transduction GO:0007265 162 100 2,000 9,554E-04 0,01979729 ! fat cell differentiation GO:0045444 37 24 1,000 9,865E-04 0,02025816 ! negative regulation of protein modification process GO:0031400 50 26 1,000 1,159E-03 0,02358609 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 1,25E-03 0,02521879 ! protein targeting to membrane GO:0006612 53 29 1,000 1,442E-03 0,02884646 ! eye morphogenesis GO:0048592 51 29 1,000 1,442E-03 0,02859778 ! negative regulation of cell activation GO:0050866 44 30 1,000 1,543E-03 0,03034163 ! response to heat GO:0009408 41 30 1,000 1,543E-03 0,0300845 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 1,756E-03 0,03393227 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 1,867E-03 0,03577686 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 1,867E-03 0,03548118 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 1,867E-03 0,03519036 ! cell junction organization GO:0034330 63 33 1,000 1,867E-03 0,03490425 ! establishment or maintenance of cell polarity GO:0007163 61 34 1,000 1,981E-03 0,03674195 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 1,981E-03 0,03644801 ! keratinocyte differentiation GO:0030216 47 35 1,000 2,098E-03 0,03830355 ! learning GO:0007612 67 37 1,000 2,343E-03 0,04243325 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 2,47E-03 0,0443867 ! striated muscle cell differentiation GO:0051146 54 38 1,000 2,47E-03 0,04404262 ! phagocytosis GO:0006909 60 38 1,000 2,47E-03 0,04370383 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 2,601E-03 0,04565898 ! cell growth GO:0016049 61 39 1,000 2,601E-03 0,04531308 ! epidermal cell differentiation GO:0009913 53 40 1,000 2,734E-03 0,0472818 ! vesicle organization GO:0016050 79 43 1,000 3,154E-03 0,05413148 ! positive regulation of cell cycle GO:0045787 77 45 1,000 3,449E-03 0,05876416 ! response to UV GO:0009411 75 46 1,000 3,602E-03 0,06090946 ! negative regulation of immune system process GO:0002683 73 47 1,000 3,757E-03 0,06307549 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 3,757E-03 0,06261842 ! response to temperature stimulus GO:0009266 62 48 1,000 3,916E-03 0,06479211 ! regulation of DNA replication GO:0006275 75 48 1,000 3,916E-03 0,06432931 ! positive regulation of cytokine production GO:0001819 73 48 1,000 3,916E-03 0,06387307 ! regulation of angiogenesis GO:0045765 94 49 1,000 4,077E-03 0,06604184 ! aging GO:0007568 79 52 1,000 4,581E-03 0,07367585 ! cell projection assembly GO:0030031 76 53 1,000 4,755E-03 0,07594111 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 5,294E-03 0,08397715 ! activation of MAPK activity GO:0000187 84 59 1,000 5,861E-03 0,09232605 ! actin filament organization GO:0007015 95 59 1,000 5,861E-03 0,09169798 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 6,253E-03 0,0971768 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 6,454E-03 0,09962117 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 6,657E-03 0,10207762 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 6,864E-03 0,10454576 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 7,073E-03 0,10702516 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 7,073E-03 0,10632565 ! learning or memory GO:0007611 123 68 1,000 7,718E-03 0,11527085 ! positive regulation of ligase activity GO:0051351 99 69 1,000 7,939E-03 0,11780301 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 8,162E-03 0,12034449 ! eye development GO:0001654 111 70 1,000 8,162E-03 0,11957797 ! muscle cell differentiation GO:0042692 104 71 1,000 8,389E-03 0,12211716 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 8,389E-03 0,12134912 ! regulation of synaptic transmission GO:0050804 109 72 1,000 8,618E-03 0,12388593 ! negative regulation of transport GO:0051051 116 73 1,000 8,85E-03 0,12643125 ! regulation of ligase activity GO:0051340 114 75 1,000 9,323E-03 0,13235816 ! response to unfolded protein GO:0006986 99 76 1,000 9,563E-03 0,13493791 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 9,688E-03 0,13586325 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 9,688E-03 0,13503984 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 9,688E-03 0,13422635 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 9,688E-03 0,1334226 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 9,688E-03 0,13262841 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,688E-03 0,13184363 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 9,688E-03 0,13106808 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 9,688E-03 0,1303016 ! sleep GO:0030431 11 5 0,000 9,688E-03 0,12954403 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,688E-03 0,12879522 ! nucleotide-sugar transport GO:0015780 8 5 0,000 9,688E-03 0,12805502 ! regulation of interferon-beta production GO:0032648 5 5 0,000 9,688E-03 0,12732328 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 9,688E-03 0,12659985 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 9,688E-03 0,1258846 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 9,688E-03 0,12517738 ! tongue development GO:0043586 6 5 0,000 9,688E-03 0,12447806 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 9,688E-03 0,12378652 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 9,688E-03 0,12310262 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 9,688E-03 0,12242623 ! cobalt ion transport GO:0006824 9 5 0,000 9,688E-03 0,12175723 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 9,688E-03 0,12109551 ! SMAD protein complex assembly GO:0007183 9 5 0,000 9,688E-03 0,12044094 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 9,688E-03 0,11979341 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 9,688E-03 0,1191528 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 9,688E-03 0,11851901 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 9,688E-03 0,11789192 ! embryonic camera-type eye development GO:0031076 8 5 0,000 9,688E-03 0,11727144 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 9,688E-03 0,11665745 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 9,688E-03 0,11604986 ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,688E-03 0,11544857 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 9,688E-03 0,11485347 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 9,688E-03 0,11426448 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 9,688E-03 0,1136815 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 9,688E-03 0,11310443 ! positive regulation of histone modification GO:0031058 5 5 0,000 9,688E-03 0,1125332 ! malate metabolic process GO:0006108 7 5 0,000 9,688E-03 0,11196771 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 9,688E-03 0,11140787 ! behavioral response to pain GO:0048266 7 5 0,000 9,688E-03 0,1108536 ! clathrin coat assembly GO:0048268 11 5 0,000 9,688E-03 0,11030482 ! phototransduction, visible light GO:0007603 6 5 0,000 9,688E-03 0,10976145 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,688E-03 0,1092234 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 9,688E-03 0,1086906 ! mating behavior GO:0007617 6 5 0,000 9,688E-03 0,10816298 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 9,688E-03 0,10764045 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 9,688E-03 0,10712295 ! rhythmic behavior GO:0007622 12 5 0,000 9,688E-03 0,1066104 ! copulation GO:0007620 7 5 0,000 9,688E-03 0,10610273 ! glial cell fate commitment GO:0021781 12 5 0,000 9,688E-03 0,10559987 ! protein maturation by protein folding GO:0022417 12 5 0,000 9,688E-03 0,10510176 ! embryonic hemopoiesis GO:0035162 10 5 0,000 9,688E-03 0,10460833 ! regulation of potassium ion transport GO:0043266 9 5 0,000 9,688E-03 0,1041195 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 9,688E-03 0,10363523 ! lipoprotein particle clearance GO:0034381 9 5 0,000 9,688E-03 0,10315543 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 9,688E-03 0,10268006 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,688E-03 0,10220905 ! response to protozoan GO:0001562 9 5 0,000 9,688E-03 0,10174234 ! positive regulation of glycolysis GO:0045821 11 5 0,000 9,688E-03 0,10127988 ! lymph vessel development GO:0001945 7 5 0,000 9,688E-03 0,1008216 ! endochondral ossification GO:0001958 12 5 0,000 9,688E-03 0,10036745 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 9,688E-03 0,09991737 ! parathyroid gland development GO:0060017 8 5 0,000 9,688E-03 0,09947131 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 9,688E-03 0,09902922 ! anagen GO:0042640 6 5 0,000 9,688E-03 0,09859103 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 9,688E-03 0,09815671 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 9,688E-03 0,0977262 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 9,688E-03 0,09729945 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 9,688E-03 0,09687641 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 9,688E-03 0,09645703 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 9,688E-03 0,09604127 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 9,688E-03 0,09562907 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 9,688E-03 0,0952204 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 9,688E-03 0,09481521 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 9,688E-03 0,09441345 ! cardiac muscle fiber development GO:0048739 7 5 0,000 9,688E-03 0,09401508 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 9,688E-03 0,09362006 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 9,688E-03 0,09322834 ! neutrophil mediated immunity GO:0002446 6 5 0,000 9,688E-03 0,09283989 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 9,688E-03 0,09245466 ! ovulation GO:0030728 6 5 0,000 9,688E-03 0,09207262 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 9,688E-03 0,09169372 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 9,688E-03 0,09131792 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 9,688E-03 0,0909452 ! response to pH GO:0009268 9 5 0,000 9,688E-03 0,0905755 ! proline biosynthetic process GO:0006561 6 5 0,000 9,688E-03 0,0902088 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 9,688E-03 0,08984505 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 9,688E-03 0,08948423 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 9,688E-03 0,08912629 ! polyol biosynthetic process GO:0046173 5 5 0,000 9,688E-03 0,08877121 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 9,688E-03 0,08841894 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 9,688E-03 0,08806946 ! sister chromatid cohesion GO:0007062 9 5 0,000 9,688E-03 0,08772273 ! nerve growth factor processing GO:0032455 7 5 0,000 9,688E-03 0,08737872 ! urea metabolic process GO:0019627 6 5 0,000 9,688E-03 0,0870374 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 9,688E-03 0,08669873 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 9,688E-03 0,08636269 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 9,688E-03 0,08602924 ! neutrophil activation GO:0042119 5 5 0,000 9,688E-03 0,08569836 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 9,688E-03 0,08537001 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 9,688E-03 0,08504417 ! response to food GO:0032094 5 5 0,000 9,688E-03 0,08472081 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 9,688E-03 0,0843999 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,688E-03 0,08408141 ! paraxial mesoderm development GO:0048339 9 5 0,000 9,688E-03 0,08376531 ! forebrain neuron development GO:0021884 7 5 0,000 9,688E-03 0,08345159 ! melanosome organization GO:0032438 7 5 0,000 9,688E-03 0,0831402 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 9,688E-03 0,08283113 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 9,688E-03 0,08252435 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 9,688E-03 0,08221983 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,688E-03 0,08191755 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 9,688E-03 0,08161749 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 9,688E-03 0,08131961 ! nucleoside transport GO:0015858 6 5 0,000 9,688E-03 0,0810239 ! nucleoside salvage GO:0043174 7 5 0,000 9,688E-03 0,08073034 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 9,688E-03 0,08043889 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,688E-03 0,08014955 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 9,688E-03 0,07986227 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 9,688E-03 0,07957705 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 9,688E-03 0,07929386 ! early endosome to late endosome transport GO:0045022 11 5 0,000 9,688E-03 0,07901267 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,688E-03 0,07873348 ! depyrimidination GO:0045008 8 5 0,000 9,688E-03 0,07845624 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 9,688E-03 0,07818096 ! 5S class rRNA transcription GO:0042791 8 5 0,000 9,688E-03 0,0779076 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 9,688E-03 0,07763614 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,688E-03 0,07736657 ! neuronal ion channel clustering GO:0045161 7 5 0,000 9,688E-03 0,07709887 ! sodium ion homeostasis GO:0055078 6 5 0,000 9,688E-03 0,07683301 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 9,688E-03 0,07656898 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 9,688E-03 0,07630676 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 9,688E-03 0,07604633 ! monocyte differentiation GO:0030224 8 5 0,000 9,688E-03 0,07578767 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 9,688E-03 0,07553076 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 9,688E-03 0,07527559 ! centrosome duplication GO:0051298 5 5 0,000 9,688E-03 0,07502213 ! response to UV-C GO:0010225 6 5 0,000 9,688E-03 0,07477038 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 9,688E-03 0,07452031 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 9,688E-03 0,07427191 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 9,688E-03 0,07402516 ! regulation of dendrite development GO:0050773 12 5 0,000 9,688E-03 0,07378004 ! peptidyl-arginine modification GO:0018195 7 5 0,000 9,688E-03 0,07353655 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,688E-03 0,07329465 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 9,688E-03 0,07305434 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 9,688E-03 0,0728156 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 9,688E-03 0,07257842 ! regulation of dopamine secretion GO:0014059 12 5 0,000 9,688E-03 0,07234277 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 9,688E-03 0,07210865 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 9,688E-03 0,07187604 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 9,688E-03 0,07164493 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 9,688E-03 0,0714153 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 9,688E-03 0,07118714 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 9,688E-03 0,07096043 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 9,688E-03 0,07073515 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 9,688E-03 0,07051131 ! neural tube patterning GO:0021532 6 5 0,000 9,688E-03 0,07028888 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 9,688E-03 0,07006784 ! histone demethylation GO:0016577 9 5 0,000 9,688E-03 0,06984819 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 9,688E-03 0,06962992 ! regulation of sterol transport GO:0032371 7 5 0,000 9,688E-03 0,069413 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 9,688E-03 0,06919743 ! enteric nervous system development GO:0048484 8 5 0,000 9,688E-03 0,0689832 ! establishment of planar polarity GO:0001736 6 5 0,000 9,688E-03 0,06877029 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 9,688E-03 0,06855869 ! muscle cell proliferation GO:0033002 8 5 0,000 9,688E-03 0,06834839 ! transcription termination GO:0006353 8 5 0,000 9,688E-03 0,06813937 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 9,688E-03 0,06793163 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 9,688E-03 0,06772515 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 9,688E-03 0,06751992 ! regulation of respiratory burst GO:0060263 8 5 0,000 9,688E-03 0,06731593 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 9,688E-03 0,06711317 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 9,688E-03 0,06691163 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 9,688E-03 0,0667113 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 9,688E-03 0,06651216 ! apical protein localization GO:0045176 6 5 0,000 9,688E-03 0,06631421 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 9,688E-03 0,06611743 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 9,688E-03 0,06592182 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,688E-03 0,06572736 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 9,688E-03 0,06553404 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 9,688E-03 0,06534186 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 9,688E-03 0,0651508 ! triglyceride catabolic process GO:0019433 6 5 0,000 9,688E-03 0,06496086 ! glial cell migration GO:0008347 10 5 0,000 9,688E-03 0,06477202 ! determination of adult lifespan GO:0008340 8 5 0,000 9,688E-03 0,06458427 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 9,688E-03 0,06439761 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 9,688E-03 0,06421203 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 9,688E-03 0,06402751 ! somatic stem cell maintenance GO:0035019 13 5 0,000 9,688E-03 0,06384405 ! cerebellar cortex formation GO:0021697 6 5 0,000 9,688E-03 0,06366164 ! neural plate development GO:0001840 6 5 0,000 9,688E-03 0,06348027 ! regulation of sensory perception GO:0051931 6 5 0,000 9,688E-03 0,06329992 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 9,688E-03 0,0631206 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 9,688E-03 0,0629423 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 9,688E-03 0,062765 ! sensory cilium assembly GO:0035058 6 5 0,000 9,688E-03 0,06258869 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 9,688E-03 0,06241337 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 9,688E-03 0,06223903 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 9,688E-03 0,06206566 ! spindle assembly GO:0051225 5 5 0,000 9,688E-03 0,06189326 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 9,688E-03 0,06172181 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 9,688E-03 0,06155131 ! protein amino acid prenylation GO:0018346 9 5 0,000 9,688E-03 0,06138175 ! organ regeneration GO:0031100 7 5 0,000 9,688E-03 0,06121311 ! NAD biosynthetic process GO:0009435 7 5 0,000 9,688E-03 0,06104541 ! carnitine metabolic process GO:0009437 5 5 0,000 9,688E-03 0,06087862 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 9,688E-03 0,06071273 ! cellular anion homeostasis GO:0030002 6 5 0,000 9,688E-03 0,06054775 GO:0055081|anion homeostasis, ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 9,806E-03 0,06112217 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 9,806E-03 0,06095697 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,010052 0,06231697 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,010052 0,06214945 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,01030061 0,06351582 ! cellular respiration GO:0045333 107 79 1,000 0,01030061 0,06334599 ! regulation of lyase activity GO:0051339 133 79 1,000 0,01030061 0,06317707 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,01055195 0,06454648 GO:0010498|proteasomal protein catabolic process, ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,010806 0,06592517 ! response to protein stimulus GO:0051789 111 81 1,000 0,010806 0,06575076 ! regulation of neurological system process GO:0031644 122 81 1,000 0,010806 0,06557728 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,010806 0,06540471 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,01106275 0,06678299 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,01132219 0,06817026 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cell adhesion GO:0030155 159 83 1,000 0,01132219 0,06799227 ! tRNA transcription GO:0009304 11 6 0,000 0,01161421 0,06956427 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01161421 0,06938358 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01161421 0,06920383 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01161421 0,06902501 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01161421 0,06884711 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01161421 0,06867013 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01161421 0,06849405 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01161421 0,06831887 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01161421 0,06814459 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01161421 0,06797119 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01161421 0,06779868 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01161421 0,06762703 ! prostate gland development GO:0030850 9 6 0,000 0,01161421 0,06745626 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01161421 0,06728634 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01161421 0,06711728 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01161421 0,06694907 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01161421 0,0667817 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01161421 0,06661516 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01161421 0,06644945 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01161421 0,06628456 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01161421 0,06612049 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01161421 0,06595723 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01161421 0,06579478 ! neuron adhesion GO:0007158 9 6 0,000 0,01161421 0,06563312 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01161421 0,06547225 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01161421 0,06531217 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01161421 0,06515288 ! signal peptide processing GO:0006465 8 6 0,000 0,01161421 0,06499435 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01161421 0,0648366 ! mRNA stabilization GO:0048255 15 6 0,000 0,01161421 0,06467961 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01161421 0,06452338 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01161421 0,0643679 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01161421 0,06421317 ! opsonization GO:0008228 8 6 0,000 0,01161421 0,06405918 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01161421 0,06390593 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01161421 0,06375341 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01161421 0,06360162 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01161421 0,06345054 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01161421 0,06330019 ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01161421 0,06315054 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01161421 0,0630016 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01161421 0,06285336 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01161421 0,06270582 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01161421 0,06255897 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01161421 0,0624128 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01161421 0,06226732 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01161421 0,06212251 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01161421 0,06197837 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01161421 0,0618349 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01161421 0,0616921 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01161421 0,06154995 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01161421 0,06140846 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01161421 0,06126761 ! thymic T cell selection GO:0045061 12 6 0,000 0,01161421 0,06112741 ! protein lipoylation GO:0009249 10 6 0,000 0,01161421 0,06098785 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01161421 0,06084893 ! pigment granule organization GO:0048753 11 6 0,000 0,01161421 0,06071063 ! drug transport GO:0015893 6 6 0,000 0,01161421 0,06057297 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01161421 0,06043592 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01161421 0,0602995 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01161421 0,06016369 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01161421 0,06002849 ! histidine metabolic process GO:0006547 6 6 0,000 0,01161421 0,0598939 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01161421 0,05975991 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01161421 0,05962652 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01161421 0,05949372 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01161421 0,05936151 ! adenohypophysis development GO:0021984 10 6 0,000 0,01161421 0,05922989 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01161421 0,05909885 ! hyperosmotic response GO:0006972 8 6 0,000 0,01161421 0,05896839 ! microtubule nucleation GO:0007020 10 6 0,000 0,01161421 0,0588385 ! ER overload response GO:0006983 7 6 0,000 0,01161421 0,05870918 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01161421 0,05858044 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01161421 0,05845225 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01161421 0,05832463 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01161421 0,05819756 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01161421 0,05807104 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01161421 0,05794507 ! response to dietary excess GO:0002021 7 6 0,000 0,01161421 0,05781965 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01161421 0,05769477 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01161421 0,05757043 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01161421 0,05744662 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01161421 0,05732335 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01161421 0,0572006 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01161421 0,05707837 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01161421 0,05695667 ! neuron apoptosis GO:0051402 8 6 0,000 0,01161421 0,05683549 ! organic alcohol transport GO:0015850 9 6 0,000 0,01161421 0,05671482 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01161421 0,05659466 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01161421 0,05647501 ! male sex determination GO:0030238 9 6 0,000 0,01161421 0,05635586 ! carnitine transport GO:0015879 8 6 0,000 0,01161421 0,05623722 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01161421 0,05611907 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01161421 0,05600142 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01161421 0,05588427 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01161421 0,0557676 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01161421 0,05565141 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01161421 0,05553571 ! parturition GO:0007567 12 6 0,000 0,01161421 0,0554205 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01161421 0,05530575 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01161421 0,05519149 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01161421 0,05507769 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01161421 0,05496436 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01161421 0,0548515 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01161421 0,0547391 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01161421 0,05462716 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01161421 0,05451567 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01161421 0,05440464 ! macrophage differentiation GO:0030225 10 6 0,000 0,01161421 0,05429406 ! astrocyte development GO:0014002 14 6 0,000 0,01161421 0,05418393 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01161421 0,05407425 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01161421 0,05396501 ! interaction with symbiont GO:0051702 8 6 0,000 0,01161421 0,05385621 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01161421 0,05374784 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01161421 0,05363992 ! eating behavior GO:0042755 6 6 0,000 0,01161421 0,05353242 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01161421 0,05342536 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01161421 0,05331872 ! response to copper ion GO:0046688 9 6 0,000 0,01161421 0,05321251 ! DNA topological change GO:0006265 8 6 0,000 0,01161421 0,05310672 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01161421 0,05300135 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01161421 0,05289639 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01161421 0,05279186 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01161421 0,05268773 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01161421 0,05258401 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01161421 0,0524807 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01161421 0,0523778 ! gas homeostasis GO:0033483 11 6 0,000 0,01161421 0,0522753 ! hair follicle maturation GO:0048820 7 6 0,000 0,01161421 0,0521732 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01161421 0,0520715 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01161421 0,05197019 ! Schwann cell development GO:0014044 14 6 0,000 0,01161421 0,05186928 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01161421 0,05176876 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01161421 0,05166862 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01161421 0,05156888 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01161421 0,05146952 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01161421 0,05137054 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01161421 0,05127194 ! histone ubiquitination GO:0016574 7 6 0,000 0,01161421 0,05117371 ! regulation of meiosis GO:0040020 10 6 0,000 0,01161421 0,05107587 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01161421 0,05097839 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01161421 0,05088129 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01161421 0,05078456 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01161421 0,0506882 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01161421 0,05059219 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01161421 0,05049656 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01161421 0,05040128 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01161421 0,05030636 ! receptor internalization GO:0031623 9 6 0,000 0,01161421 0,0502118 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01161421 0,0501176 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01161421 0,05002374 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01161421 0,04993024 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01161421 0,04983709 ! protein deubiquitination GO:0016579 8 6 0,000 0,01161421 0,04974428 GO:0070646|protein modification by small protein removal, ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01161421 0,04965182 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01161421 0,0495597 ! axonal fasciculation GO:0007413 9 6 0,000 0,01161421 0,04946792 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01161421 0,04937649 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01161421 0,04928539 ! midbrain development GO:0030901 6 6 0,000 0,01161421 0,04919462 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01161421 0,04910419 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01161421 0,04901409 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01161421 0,04892432 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01161421 0,04883488 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01161421 0,04874576 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01161421 0,04865697 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01161421 0,04856851 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01161421 0,04848036 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01161421 0,04839253 ! adult feeding behavior GO:0008343 6 6 0,000 0,01161421 0,04830502 ! blastocyst growth GO:0001832 15 6 0,000 0,01161421 0,04821783 ! pigment granule transport GO:0051904 12 6 0,000 0,01161421 0,04813095 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01161421 0,04804439 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01161421 0,04795813 ! catecholamine transport GO:0051937 7 6 0,000 0,01161421 0,04787218 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01161421 0,04778655 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01161421 0,04770121 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01161421 0,04761618 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01161421 0,04753146 ! protein prenylation GO:0018342 10 6 0,000 0,01161421 0,04744703 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01161421 0,04736291 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01161421 0,04727908 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01161421 0,04719555 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01161421 0,04711231 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,01184911 0,04798055 ! Golgi vesicle transport GO:0048193 138 85 1,000 0,01184911 0,04789623 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,01211657 0,0488914 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,01293478 0,05210156 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01353714 0,05443255 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01353714 0,05433755 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01353714 0,05424289 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01353714 0,05414855 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01353714 0,05405454 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01353714 0,05396086 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01353714 0,0538675 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01353714 0,05377447 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01353714 0,05368175 ! reproductive behavior GO:0019098 12 7 0,000 0,01353714 0,05358936 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01353714 0,05349728 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01353714 0,05340552 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01353714 0,05331407 ! oligopeptide transport GO:0006857 11 7 0,000 0,01353714 0,05322293 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01353714 0,05313211 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01353714 0,0530416 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01353714 0,05295139 ! RNA methylation GO:0001510 11 7 0,000 0,01353714 0,05286149 ! pericardium development GO:0060039 8 7 0,000 0,01353714 0,05277189 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01353714 0,0526826 ! fibril organization GO:0043206 13 7 0,000 0,01353714 0,05259361 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01353714 0,05250492 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01353714 0,05241653 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01353714 0,05232843 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01353714 0,05224063 ! lipoprotein transport GO:0042953 9 7 0,000 0,01353714 0,05215313 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01353714 0,05206591 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01353714 0,05197899 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01353714 0,05189236 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01353714 0,05180602 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01353714 0,05171996 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01353714 0,05163419 ! chemosensory behavior GO:0007635 9 7 0,000 0,01353714 0,0515487 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01353714 0,0514635 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01353714 0,05137858 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01353714 0,05129393 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01353714 0,05120957 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01353714 0,05112548 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01353714 0,05104167 ! reflex GO:0060004 12 7 0,000 0,01353714 0,05095813 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01353714 0,05087486 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01353714 0,05079187 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01353714 0,05070915 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01353714 0,05062669 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01353714 0,05054451 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01353714 0,05046259 ! spinal cord patterning GO:0021511 7 7 0,000 0,01353714 0,05038093 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01353714 0,05029954 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01353714 0,05021841 ! adrenal gland development GO:0030325 17 7 0,000 0,01353714 0,05013755 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01353714 0,05005694 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01353714 0,04997659 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01353714 0,0498965 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01353714 0,04981667 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01353714 0,04973709 ! endosome organization GO:0007032 10 7 0,000 0,01353714 0,04965776 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01353714 0,04957869 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01353714 0,04949987 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01353714 0,0494213 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01353714 0,04934297 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01353714 0,0492649 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01353714 0,04918707 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01353714 0,04910949 ! galactose metabolic process GO:0006012 10 7 0,000 0,01353714 0,04903215 ! vesicle fusion GO:0006906 15 7 0,000 0,01353714 0,04895506 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01353714 0,04887821 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01353714 0,04880159 ! organ growth GO:0035265 11 7 0,000 0,01353714 0,04872522 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01353714 0,04864909 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01353714 0,04857319 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01353714 0,04849753 ! retinol metabolic process GO:0042572 9 7 0,000 0,01353714 0,04842211 ! behavioral fear response GO:0001662 13 7 0,000 0,01353714 0,04834692 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01353714 0,04827196 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01353714 0,04819724 ! rRNA modification GO:0000154 12 7 0,000 0,01353714 0,04812275 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01353714 0,04804848 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01353714 0,04797445 ! response to UV-B GO:0010224 11 7 0,000 0,01353714 0,04790064 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01353714 0,04782706 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01353714 0,04775371 ! intermediate filament organization GO:0045109 11 7 0,000 0,01353714 0,04768058 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01353714 0,04760767 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01353714 0,04753499 ! fibrinolysis GO:0042730 9 7 0,000 0,01353714 0,04746253 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01353714 0,04739028 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01353714 0,04731826 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01353714 0,04724646 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01353714 0,04717487 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01353714 0,0471035 ! response to tropane GO:0014073 13 7 0,000 0,01353714 0,04703235 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01353714 0,04696141 ! melanosome localization GO:0032400 10 7 0,000 0,01353714 0,04689069 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01353714 0,04682018 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01353714 0,04674988 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01353714 0,04667979 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01353714 0,04660991 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01353714 0,04654023 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01353714 0,04647077 ! mast cell activation GO:0045576 9 7 0,000 0,01353714 0,04640152 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01353714 0,04633247 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01353714 0,04626362 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01353714 0,04619498 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01353714 0,04612654 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01353714 0,04605831 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01353714 0,04599028 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01353714 0,04592244 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01353714 0,04585481 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01353714 0,04578738 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01353714 0,04572014 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01353714 0,0456531 ! response to tumor cell GO:0002347 12 7 0,000 0,01353714 0,04558626 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01353714 0,04551962 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01353714 0,04545316 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01353714 0,0453869 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01353714 0,04532084 ! diuresis GO:0030146 12 7 0,000 0,01353714 0,04525497 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01353714 0,04518928 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01353714 0,04512379 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01353714 0,04505849 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01353714 0,04499338 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01353714 0,04492845 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01353714 0,04486371 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01353714 0,04479916 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01353714 0,04473479 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01353714 0,04467061 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01353714 0,04460661 ! lymph node development GO:0048535 9 7 0,000 0,01353714 0,0445428 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01353714 0,04447917 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01353714 0,04441572 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01353714 0,04435245 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01353714 0,04428936 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01353714 0,04422644 ! ATP catabolic process GO:0006200 10 7 0,000 0,01353714 0,04416371 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01353714 0,04410116 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01353714 0,04403878 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01353714 0,04397658 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01353714 0,04391455 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01353714 0,0438527 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01353714 0,04379102 ! muscle adaptation GO:0043500 12 7 0,000 0,01353714 0,04372952 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01353714 0,04366819 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01353714 0,04360703 ! retina homeostasis GO:0001895 9 7 0,000 0,01353714 0,04354604 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01353714 0,04348522 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01353714 0,04342457 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01353714 0,04336409 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01353714 0,04330378 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01353714 0,04324363 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01353714 0,04318366 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01353714 0,04312385 ! response to oxidative stress GO:0006979 141 94 1,000 0,01435066 0,04565218 ! angiogenesis GO:0001525 149 95 1,000 0,01464157 0,04651329 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,01493504 0,04738012 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01545644 0,04896667 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01545644 0,04889932 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01545644 0,04883215 ! axon extension GO:0048675 11 8 0,000 0,01545644 0,04876516 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01545644 0,04869836 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01545644 0,04863174 ! associative learning GO:0008306 15 8 0,000 0,01545644 0,0485653 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01545644 0,04849905 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01545644 0,04843297 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01545644 0,04836708 ! phosphate transport GO:0006817 10 8 0,000 0,01545644 0,04830136 ! N-glycan processing GO:0006491 12 8 0,000 0,01545644 0,04823582 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01545644 0,04817046 ! UTP metabolic process GO:0046051 8 8 0,000 0,01545644 0,04810528 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01545644 0,04804027 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01545644 0,04797544 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01545644 0,04791079 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01545644 0,0478463 ! succinate metabolic process GO:0006105 14 8 0,000 0,01545644 0,04778199 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01545644 0,04771786 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01545644 0,04765389 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01545644 0,0475901 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01545644 0,04752647 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01545644 0,04746302 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01545644 0,04739974 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01545644 0,04733662 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01545644 0,04727367 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01545644 0,04721089 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01545644 0,04714828 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01545644 0,04708583 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01545644 0,04702355 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01545644 0,04696143 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01545644 0,04689948 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01545644 0,04683768 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01545644 0,04677606 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01545644 0,04671459 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01545644 0,04665328 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01545644 0,04659214 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01545644 0,04653116 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01545644 0,04647033 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01545644 0,04640966 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01545644 0,04634916 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01545644 0,04628881 ! melanin metabolic process GO:0006582 12 8 0,000 0,01545644 0,04622861 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01545644 0,04616858 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01545644 0,04610869 ! macrophage activation GO:0042116 12 8 0,000 0,01545644 0,04604897 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01545644 0,0459894 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01545644 0,04592998 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01545644 0,04587071 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01545644 0,0458116 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01545644 0,04575264 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01545644 0,04569383 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01545644 0,04563518 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01545644 0,04557667 ! ruffle organization GO:0031529 11 8 0,000 0,01545644 0,04551831 ! osteoblast development GO:0002076 13 8 0,000 0,01545644 0,04546011 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01545644 0,04540205 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01545644 0,04534414 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01545644 0,04528637 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01545644 0,04522876 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01545644 0,04517129 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01545644 0,04511396 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01545644 0,04505678 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01545644 0,04499975 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01545644 0,04494286 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01545644 0,04488611 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01545644 0,04482951 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01545644 0,04477305 ! segment specification GO:0007379 10 8 0,000 0,01545644 0,04471673 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01545644 0,04466056 ! cellular extravasation GO:0045123 11 8 0,000 0,01545644 0,04460452 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01545644 0,04454863 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01545644 0,04449287 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01545644 0,04443725 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01545644 0,04438178 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01545644 0,04432644 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01545644 0,04427124 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01545644 0,04421617 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01545644 0,04416125 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01545644 0,04410646 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01545644 0,0440518 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01545644 0,04399728 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01545644 0,0439429 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01545644 0,04388865 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01545644 0,04383453 ! icosanoid secretion GO:0032309 12 8 0,000 0,01545644 0,04378055 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01545644 0,04372669 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01545644 0,04367298 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01545644 0,04361939 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01545644 0,04356593 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01545644 0,04351261 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01545644 0,04345942 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01545644 0,04340635 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01545644 0,04335342 ! sterol catabolic process GO:0016127 9 8 0,000 0,01545644 0,04330061 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01545644 0,04324794 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01545644 0,04319539 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01545644 0,04314296 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01545644 0,04309067 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01545644 0,0430385 ! prophase GO:0051324 11 8 0,000 0,01545644 0,04298646 ! S phase GO:0051320 8 8 0,000 0,01545644 0,04293454 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01545644 0,04288275 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01545644 0,04283109 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01545644 0,04277955 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01545644 0,04272813 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01545644 0,04267683 ! hormone catabolic process GO:0042447 13 8 0,000 0,01545644 0,04262566 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01545644 0,04257461 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01545644 0,04252369 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01545644 0,04247288 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01545644 0,0424222 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01545644 0,04237164 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01545644 0,04232119 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01545644 0,04227087 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01545644 0,04222067 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01545644 0,04217058 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01545644 0,04212062 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01545644 0,04207077 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01545644 0,04202104 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,01583065 0,0429876 ! regulation of translation GO:0006417 151 100 1,000 0,01613423 0,04376029 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01737211 0,04706225 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01737211 0,04700688 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01737211 0,04695165 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01737211 0,04689654 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01737211 0,04684156 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01737211 0,04678671 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01737211 0,04673199 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01737211 0,0466774 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01737211 0,04662293 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01737211 0,04656859 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01737211 0,04651438 ! GTP metabolic process GO:0046039 9 9 0,000 0,01737211 0,04646029 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01737211 0,04640633 ! social behavior GO:0035176 14 9 0,000 0,01737211 0,0463525 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01737211 0,04629879 ! artery development GO:0060840 19 9 0,000 0,01737211 0,0462452 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01737211 0,04619174 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01737211 0,0461384 ! response to pain GO:0048265 16 9 0,000 0,01737211 0,04608518 ! protein complex disassembly GO:0043241 17 9 0,000 0,01737211 0,04603209 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01737211 0,04597912 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01737211 0,04592627 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01737211 0,04587354 ! lung alveolus development GO:0048286 17 9 0,000 0,01737211 0,04582093 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01737211 0,04576844 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01737211 0,04571608 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01737211 0,04566383 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01737211 0,0456117 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01737211 0,04555969 ! protein targeting to ER GO:0045047 19 9 0,000 0,01737211 0,0455078 ! T cell selection GO:0045058 18 9 0,000 0,01737211 0,04545603 ! endoderm development GO:0007492 12 9 0,000 0,01737211 0,04540438 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01737211 0,04535284 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01737211 0,04530142 ! arginine catabolic process GO:0006527 10 9 0,000 0,01737211 0,04525012 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01737211 0,04519893 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01737211 0,04514786 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01737211 0,0450969 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01737211 0,04504606 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01737211 0,04499533 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01737211 0,04494472 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01737211 0,04489422 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01737211 0,04484383 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01737211 0,04479356 ! mannose metabolic process GO:0006013 9 9 0,000 0,01737211 0,0447434 ! receptor clustering GO:0043113 15 9 0,000 0,01737211 0,04469335 ! epithelial cell development GO:0002064 10 9 0,000 0,01737211 0,04464341 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01737211 0,04459359 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01737211 0,04454387 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01737211 0,04449427 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01737211 0,04444477 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01737211 0,04439539 ! motor axon guidance GO:0008045 14 9 0,000 0,01737211 0,04434612 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01737211 0,04429695 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01737211 0,0442479 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01737211 0,04419895 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01737211 0,04415011 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01737211 0,04410138 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01737211 0,04405276 ! DNA ligation GO:0006266 14 9 0,000 0,01737211 0,04400424 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01737211 0,04395583 ! response to amine stimulus GO:0014075 13 9 0,000 0,01737211 0,04390753 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01737211 0,04385933 ! erythrocyte development GO:0048821 11 9 0,000 0,01737211 0,04381124 ! renal water homeostasis GO:0003091 14 9 0,000 0,01737211 0,04376326 ! postreplication repair GO:0006301 11 9 0,000 0,01737211 0,04371537 ! mRNA cleavage GO:0006379 13 9 0,000 0,01737211 0,0436676 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01737211 0,04361993 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01737211 0,04357236 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01737211 0,04352489 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01737211 0,04347753 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01737211 0,04343027 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01737211 0,04338312 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01737211 0,04333607 ! acid secretion GO:0046717 14 9 0,000 0,01737211 0,04328911 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01737211 0,04324226 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01737211 0,04319552 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01737211 0,04314887 ! purine base metabolic process GO:0006144 18 9 0,000 0,01737211 0,04310232 ! oocyte differentiation GO:0009994 12 9 0,000 0,01737211 0,04305588 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01737211 0,04300953 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01737211 0,04296328 ! spleen development GO:0048536 15 9 0,000 0,01737211 0,04291713 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01737211 0,04287109 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01737211 0,04282514 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01737211 0,04277928 ! detection of calcium ion GO:0005513 13 9 0,000 0,01737211 0,04273353 ! blastocyst formation GO:0001825 12 9 0,000 0,01737211 0,04268788 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01737211 0,04264232 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01737211 0,04259686 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01737211 0,04255149 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01737211 0,04250623 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01737211 0,04246105 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01737211 0,04241598 ! prepulse inhibition GO:0060134 14 9 0,000 0,01737211 0,042371 ! embryonic placenta development GO:0001892 12 9 0,000 0,01737211 0,04232611 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01737211 0,04228133 ! insulin secretion GO:0030073 17 9 0,000 0,01737211 0,04223663 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01737211 0,04219203 ! response to nicotine GO:0035094 16 9 0,000 0,01737211 0,04214752 ! nucleus localization GO:0051647 15 9 0,000 0,01737211 0,04210311 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01737211 0,04205879 ! localization within membrane GO:0051668 15 9 0,000 0,01737211 0,04201457 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01928417 0,0465899 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01928417 0,04654101 ! neuron fate specification GO:0048665 11 10 0,000 0,01928417 0,04649222 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01928417 0,04644354 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01928417 0,04639496 ! thyroid gland development GO:0030878 19 10 0,000 0,01928417 0,04634648 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01928417 0,0462981 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01928417 0,04624982 ! synapsis GO:0007129 13 10 0,000 0,01928417 0,04620165 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01928417 0,04615357 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01928417 0,04610559 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01928417 0,04605772 ! sulfate transport GO:0008272 12 10 0,000 0,01928417 0,04600994 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01928417 0,04596226 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01928417 0,04591468 ! androgen metabolic process GO:0008209 13 10 0,000 0,01928417 0,0458672 ! phospholipid efflux GO:0033700 16 10 0,000 0,01928417 0,04581981 ! hippocampus development GO:0021766 19 10 0,000 0,01928417 0,04577253 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01928417 0,04572534 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01928417 0,04567825 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01928417 0,04563126 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01928417 0,04558436 ! pathogenesis GO:0009405 13 10 0,000 0,01928417 0,04553756 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01928417 0,04549085 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01928417 0,04544424 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01928417 0,04539773 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01928417 0,04535131 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01928417 0,04530498 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01928417 0,04525876 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01928417 0,04521262 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01928417 0,04516658 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01928417 0,04512063 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01928417 0,04507478 ! response to X-ray GO:0010165 16 10 0,000 0,01928417 0,04502902 ! B cell proliferation GO:0042100 14 10 0,000 0,01928417 0,04498335 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01928417 0,04493777 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01928417 0,04489229 ! forebrain cell migration GO:0021885 17 10 0,000 0,01928417 0,0448469 ! lipid digestion GO:0044241 15 10 0,000 0,01928417 0,0448016 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01928417 0,04475639 ! UV protection GO:0009650 14 10 0,000 0,01928417 0,04471127 ! entry into host cell GO:0030260 20 10 0,000 0,01928417 0,04466624 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01928417 0,04462131 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01928417 0,04457646 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01928417 0,04453171 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01928417 0,04448704 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01928417 0,04444247 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01928417 0,04439798 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01928417 0,04435358 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01928417 0,04430927 ! regulation of organ growth GO:0046620 11 10 0,000 0,01928417 0,04426505 ! response to dsRNA GO:0043331 18 10 0,000 0,01928417 0,04422092 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01928417 0,04417687 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01928417 0,04413292 ! embryonic axis specification GO:0000578 12 10 0,000 0,01928417 0,04408905 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01928417 0,04404526 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01928417 0,04400157 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01928417 0,04395796 ! cranial nerve development GO:0021545 12 10 0,000 0,01928417 0,04391444 ! fucose catabolic process GO:0019317 16 10 0,000 0,01928417 0,043871 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01928417 0,04382765 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01928417 0,04378438 ! protein sumoylation GO:0016925 12 10 0,000 0,01928417 0,0437412 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01928417 0,04369811 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01928417 0,0436551 ! zymogen activation GO:0031638 14 10 0,000 0,01928417 0,04361217 ! salivary gland development GO:0007431 22 10 0,000 0,01928417 0,04356933 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01928417 0,04352658 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01928417 0,0434839 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01928417 0,04344131 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01928417 0,04339881 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01928417 0,04335638 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01928417 0,04331404 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01928417 0,04327179 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01928417 0,04322961 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01928417 0,04318752 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01928417 0,04314551 ! detection of bacterium GO:0016045 10 10 0,000 0,01928417 0,04310358 ! embryonic gut development GO:0048566 11 10 0,000 0,01928417 0,04306173 ! activation of innate immune response GO:0002218 10 10 0,000 0,01928417 0,04301996 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01928417 0,04297828 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01928417 0,04293667 ! developmental induction GO:0031128 13 10 0,000 0,01928417 0,04289515 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01928417 0,0428537 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01928417 0,04281234 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01928417 0,04277105 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01928417 0,04272985 ! rRNA transcription GO:0009303 17 11 0,000 0,02119261 0,04691338 ! respiratory burst GO:0045730 14 11 0,000 0,02119261 0,04686827 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02119261 0,04682325 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02119261 0,04677831 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02119261 0,04673346 ! virus-host interaction GO:0019048 17 11 0,000 0,02119261 0,0466887 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,02119261 0,04664402 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,02119261 0,04659943 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,02119261 0,04655492 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02119261 0,0465105 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02119261 0,04646616 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,02119261 0,04642191 ! mating GO:0007618 14 11 0,000 0,02119261 0,04637774 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02119261 0,04633365 ! T cell proliferation GO:0042098 20 11 0,000 0,02119261 0,04628965 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02119261 0,04624573 ! bone resorption GO:0045453 16 11 0,000 0,02119261 0,0462019 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02119261 0,04615815 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02119261 0,04611448 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02119261 0,04607089 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02119261 0,04602739 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02119261 0,04598396 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02119261 0,04594062 ! syncytium formation GO:0006949 15 11 0,000 0,02119261 0,04589737 ! plasma membrane organization GO:0007009 18 11 0,000 0,02119261 0,04585419 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02119261 0,04581109 ! focal adhesion formation GO:0048041 24 11 0,000 0,02119261 0,04576808 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02119261 0,04572514 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02119261 0,04568229 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02119261 0,04563951 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02119261 0,04559682 ! adult heart development GO:0007512 11 11 0,000 0,02119261 0,04555421 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,02119261 0,04551167 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02119261 0,04546922 ! temperature homeostasis GO:0001659 16 11 0,000 0,02119261 0,04542684 ! L-glutamate transport GO:0015813 16 11 0,000 0,02119261 0,04538455 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02119261 0,04534233 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02119261 0,04530019 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02119261 0,04525813 ! stem cell development GO:0048864 29 11 0,000 0,02119261 0,04521614 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02119261 0,04517424 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02119261 0,04513241 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02119261 0,04509066 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02119261 0,04504899 ! vasoconstriction GO:0042310 15 11 0,000 0,02119261 0,04500739 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02119261 0,04496587 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02119261 0,04492443 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02119261 0,04488306 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02119261 0,04484177 ! ribosome assembly GO:0042255 13 11 0,000 0,02119261 0,04480055 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02119261 0,04475941 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02119261 0,04471835 ! chromatin silencing GO:0006342 19 11 0,000 0,02119261 0,04467736 ! nucleosome positioning GO:0016584 13 11 0,000 0,02119261 0,04463645 ! T cell homeostasis GO:0043029 20 11 0,000 0,02119261 0,04459561 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02119261 0,04455485 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02119261 0,04451416 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02119261 0,04447354 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02119261 0,044433 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02119261 0,04439253 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02119261 0,04435214 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02119261 0,04431182 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02119261 0,04427157 ! male genitalia development GO:0030539 13 11 0,000 0,02119261 0,0442314 ! cholesterol efflux GO:0033344 19 11 0,000 0,02119261 0,0441913 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02119261 0,04415127 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02119261 0,04411131 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,02119261 0,04407143 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02119261 0,04403162 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02119261 0,04399188 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02119261 0,04395221 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02119261 0,04391261 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02119261 0,04387309 ! lysogeny GO:0030069 18 11 0,000 0,02119261 0,04383363 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02119261 0,04379425 ! acrosome reaction GO:0007340 13 11 0,000 0,02119261 0,04375494 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02119261 0,0437157 ! lactation GO:0007595 20 12 0,000 0,02309745 0,04760227 ! reproductive cellular process GO:0048610 14 12 0,000 0,02309745 0,04755965 ! tRNA modification GO:0006400 14 12 0,000 0,02309745 0,04751711 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02309745 0,04747465 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02309745 0,04743226 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02309745 0,04738995 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02309745 0,04734771 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02309745 0,04730555 ! non-recombinational repair GO:0000726 19 12 0,000 0,02309745 0,04726346 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02309745 0,04722145 ! peroxisomal transport GO:0043574 21 12 0,000 0,02309745 0,04717951 ! cartilage condensation GO:0001502 18 12 0,000 0,02309745 0,04713765 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02309745 0,04709586 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02309745 0,04705415 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02309745 0,04701251 ! heart looping GO:0001947 15 12 0,000 0,02309745 0,04697094 ! palate development GO:0060021 15 12 0,000 0,02309745 0,04692945 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,02309745 0,04688803 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02309745 0,04684668 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02309745 0,0468054 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02309745 0,0467642 ! arginine metabolic process GO:0006525 13 12 0,000 0,02309745 0,04672307 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02309745 0,04668201 ! methionine metabolic process GO:0006555 13 12 0,000 0,02309745 0,04664103 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02309745 0,04660012 ! Golgi organization GO:0007030 18 12 0,000 0,02309745 0,04655928 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02309745 0,04651851 ! monoamine transport GO:0015844 13 12 0,000 0,02309745 0,04647781 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02309745 0,04643718 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02309745 0,04639662 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02309745 0,04635614 ! L-amino acid transport GO:0015807 20 12 0,000 0,02309745 0,04631572 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02309745 0,04627538 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02309745 0,0462351 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02309745 0,0461949 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02309745 0,04615476 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02309745 0,0461147 ! cerebellum development GO:0021549 13 12 0,000 0,02309745 0,0460747 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02309745 0,04603478 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02309745 0,04599492 ! histone acetylation GO:0016573 23 12 0,000 0,02309745 0,04595513 ! histone methylation GO:0016571 15 12 0,000 0,02309745 0,04591541 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02309745 0,04587576 ! gland morphogenesis GO:0022612 23 12 0,000 0,02309745 0,04583618 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02309745 0,04579667 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,02309745 0,04575722 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02309745 0,04571784 ! response to gamma radiation GO:0010332 20 12 0,000 0,02309745 0,04567853 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02309745 0,04563929 ! intestinal absorption GO:0050892 19 12 0,000 0,02309745 0,04560011 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02309745 0,04556101 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02309745 0,04552196 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02309745 0,04548299 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02309745 0,04544408 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02309745 0,04540524 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02309745 0,04536647 ! microspike assembly GO:0030035 23 12 0,000 0,02309745 0,04532776 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02309745 0,04528912 ! response to cold GO:0009409 14 12 0,000 0,02309745 0,04525054 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02499869 0,04893361 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02499869 0,048892 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02499869 0,04885046 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02499869 0,04880899 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02499869 0,04876759 ! water transport GO:0006833 17 13 0,000 0,02499869 0,04872626 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02499869 0,048685 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02499869 0,04864381 ! lipid localization GO:0010876 24 13 0,000 0,02499869 0,04860269 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02499869 0,04856165 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02499869 0,04852067 ! organelle fusion GO:0048284 28 13 0,000 0,02499869 0,04847975 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02499869 0,04843891 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02499869 0,04839814 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02499869 0,04835743 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02499869 0,0483168 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02499869 0,04827623 ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02499869 0,04823573 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02499869 0,0481953 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02499869 0,04815493 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02499869 0,04811463 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02499869 0,0480744 ! NAD metabolic process GO:0019674 21 13 0,000 0,02499869 0,04803424 ! exocrine system development GO:0035272 27 13 0,000 0,02499869 0,04799415 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02499869 0,04795412 ! bone mineralization GO:0030282 15 13 0,000 0,02499869 0,04791416 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02499869 0,04787426 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02499869 0,04783443 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02499869 0,04779467 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02499869 0,04775497 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02499869 0,04771534 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02499869 0,04767578 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02499869 0,04763628 ! genitalia development GO:0048806 15 13 0,000 0,02499869 0,04759684 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02499869 0,04755748 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02499869 0,04751817 ! cellular pigmentation GO:0033059 24 13 0,000 0,02499869 0,04747893 ! tissue regeneration GO:0042246 21 13 0,000 0,02499869 0,04743976 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02499869 0,04740065 ! cofactor transport GO:0051181 19 13 0,000 0,02499869 0,0473616 ! NADP metabolic process GO:0006739 18 13 0,000 0,02499869 0,04732262 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02499869 0,04728371 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02499869 0,04724485 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02499869 0,04720607 ! gas transport GO:0015669 18 13 0,000 0,02499869 0,04716734 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02499869 0,04712868 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02499869 0,04709008 ! regulation of axon extension GO:0030516 23 13 0,000 0,02499869 0,04705155 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02499869 0,04701307 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02499869 0,04697466 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02499869 0,04693632 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02499869 0,04689803 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02499869 0,04685981 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02689634 0,05037588 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02689634 0,05033489 ! superoxide anion generation GO:0042554 18 14 0,000 0,02689634 0,05029397 ! neuron maturation GO:0042551 21 14 0,000 0,02689634 0,05025311 ! regulation of S phase GO:0033261 18 14 0,000 0,02689634 0,05021232 ! myotube differentiation GO:0014902 21 14 0,000 0,02689634 0,0501716 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02689634 0,05013094 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02689634 0,05009035 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,02689634 0,05004982 ! inositol metabolic process GO:0006020 20 14 0,000 0,02689634 0,05000936 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02689634 0,04996897 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02689634 0,04992864 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02689634 0,04988837 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02689634 0,04984817 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02689634 0,04980804 ! response to cAMP GO:0051591 19 14 0,000 0,02689634 0,04976797 ! limbic system development GO:0021761 25 14 0,000 0,02689634 0,04972796 ! startle response GO:0001964 21 14 0,000 0,02689634 0,04968802 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02689634 0,04964814 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02689634 0,04960833 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02689634 0,04956858 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02689634 0,04952889 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02689634 0,04948927 ! glycine metabolic process GO:0006544 22 14 0,000 0,02689634 0,04944971 ! pituitary gland development GO:0021983 23 14 0,000 0,02689634 0,04941021 ! cellular response to starvation GO:0009267 21 14 0,000 0,02689634 0,04937078 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,02689634 0,04933141 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,02689634 0,0492921 ! regulation of heart rate GO:0002027 23 14 0,000 0,02689634 0,04925285 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02689634 0,04921367 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,02689634 0,04917455 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02689634 0,04913549 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02689634 0,04909649 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02689634 0,04905756 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02689634 0,04901869 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02689634 0,04897988 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02689634 0,04894113 ! axon cargo transport GO:0008088 27 14 0,000 0,02689634 0,04890244 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02689634 0,04886381 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02689634 0,04882524 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02689634 0,04878674 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02689634 0,04874829 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02689634 0,04870991 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02689634 0,04867158 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02689634 0,04863332 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02689634 0,04859512 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02689634 0,04855697 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02689634 0,04851889 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02689634 0,04848086 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,02689634 0,0484429 ! muscle maintenance GO:0046716 19 14 0,000 0,02689634 0,04840499 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02689634 0,04836715 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02689634 0,04832936 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02689634 0,04829163 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02689634 0,04825396 ! cell killing GO:0001906 20 14 0,000 0,02689634 0,04821635 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,02689634 0,0481788 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02689634 0,04814131 ! cilium assembly GO:0042384 20 14 0,000 0,02689634 0,04810387 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02689634 0,0480665 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02879041 0,05141144 ! positive regulation of cell size GO:0045793 20 15 0,000 0,02879041 0,05137155 ! metencephalon development GO:0022037 19 15 0,000 0,02879041 0,05133173 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02879041 0,05129197 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02879041 0,05125227 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02879041 0,05121263 ! skin development GO:0043588 25 15 0,000 0,02879041 0,05117305 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02879041 0,05113354 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02879041 0,05109408 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02879041 0,05105469 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02879041 0,05101536 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02879041 0,05097608 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02879041 0,05093687 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02879041 0,05089772 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02879041 0,05085863 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02879041 0,05081959 ! adult walking behavior GO:0007628 25 15 0,000 0,02879041 0,05078062 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02879041 0,05074171 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02879041 0,05070286 ! myoblast differentiation GO:0045445 27 15 0,000 0,02879041 0,05066406 ! centrosome cycle GO:0007098 16 15 0,000 0,02879041 0,05062533 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02879041 0,05058666 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02879041 0,05054804 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02879041 0,05050948 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02879041 0,05047098 ! cerebral cortex development GO:0021987 29 15 0,000 0,02879041 0,05043255 ! response to osmotic stress GO:0006970 22 15 0,000 0,02879041 0,05039416 ! vesicle coating GO:0006901 25 15 0,000 0,02879041 0,05035584 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02879041 0,05031758 ! DNA integration GO:0015074 22 15 0,000 0,02879041 0,05027937 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02879041 0,05024122 ! peptide secretion GO:0002790 27 15 0,000 0,02879041 0,05020313 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02879041 0,0501651 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02879041 0,05012712 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02879041 0,05008921 ! neuron recognition GO:0008038 22 15 0,000 0,02879041 0,05005135 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02879041 0,05001354 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02879041 0,0499758 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02879041 0,04993811 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02879041 0,04990048 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02879041 0,0498629 ! biomineral formation GO:0031214 18 15 0,000 0,02879041 0,04982538 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02879041 0,04978792 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02879041 0,04975051 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02879041 0,04971316 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02879041 0,04967587 ! organic cation transport GO:0015695 19 15 0,000 0,02879041 0,04963863 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02879041 0,04960145 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02879041 0,04956432 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02879041 0,04952725 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02879041 0,04949023 ! defense response to virus GO:0051607 27 15 0,000 0,02879041 0,04945327 ! peptide hormone processing GO:0016486 19 15 0,000 0,02879041 0,04941637 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02879041 0,04937952 ! protein secretion GO:0009306 27 16 0,000 0,03068089 0,05258275 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,03068089 0,0525436 ! hormone secretion GO:0046879 25 16 0,000 0,03068089 0,0525045 ! bone remodeling GO:0046849 24 16 0,000 0,03068089 0,05246547 ! endothelial cell migration GO:0043542 22 16 0,000 0,03068089 0,05242649 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,03068089 0,05238757 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,03068089 0,0523487 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03068089 0,0523099 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,03068089 0,05227115 ! glial cell development GO:0021782 24 16 0,000 0,03068089 0,05223246 ! patterning of blood vessels GO:0001569 24 16 0,000 0,03068089 0,05219382 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,03068089 0,05215525 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,03068089 0,05211673 ! protein polyubiquitination GO:0000209 26 16 0,000 0,03068089 0,05207827 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,03068089 0,05203986 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,03068089 0,05200151 ! regulation of protein binding GO:0043393 27 16 0,000 0,03068089 0,05196322 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,03068089 0,05192498 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,03068089 0,0518868 ! protein export from nucleus GO:0006611 24 16 0,000 0,03068089 0,05184868 ! negative regulation of immune response GO:0050777 28 16 0,000 0,03068089 0,05181061 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,03068089 0,0517726 ! DNA replication initiation GO:0006270 25 16 0,000 0,03068089 0,05173464 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,03068089 0,05169674 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,03068089 0,05165889 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,03068089 0,0516211 ! diencephalon development GO:0021536 25 16 0,000 0,03068089 0,05158337 ! oogenesis GO:0048477 23 16 0,000 0,03068089 0,05154569 ! neural crest cell migration GO:0001755 24 16 0,000 0,03068089 0,05150807 ! G1 phase GO:0051318 27 16 0,000 0,03068089 0,0514705 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,03068089 0,05143298 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,03068089 0,05139552 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,03068089 0,05135812 ! steroid catabolic process GO:0006706 22 16 0,000 0,03068089 0,05132076 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,03068089 0,05128347 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,03068089 0,05124622 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,03068089 0,05120904 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,03068089 0,0511719 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,03068089 0,05113482 ! sperm-egg recognition GO:0035036 16 16 0,000 0,03068089 0,05109779 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,03068089 0,05106082 ! nerve development GO:0021675 18 16 0,000 0,03068089 0,0510239 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,03068089 0,05098703 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,03068089 0,05095022 ! negative regulation of translation GO:0017148 22 16 0,000 0,03068089 0,05091346 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,03256781 0,05400573 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,03256781 0,05396683 ! negative regulation of defense response GO:0031348 19 17 0,000 0,03256781 0,05392797 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,03256781 0,05388918 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,03256781 0,05385043 ! glycerol metabolic process GO:0006071 20 17 0,000 0,03256781 0,05381175 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,03256781 0,05377312 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,03256781 0,05373454 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,03256781 0,05369602 ! signal complex assembly GO:0007172 29 17 0,000 0,03256781 0,05365756 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,03256781 0,05361915 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,03256781 0,0535808 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,03256781 0,0535425 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,03256781 0,05350425 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,03256781 0,05346606 ! memory GO:0007613 25 17 0,000 0,03256781 0,05342793 ! keratinization GO:0031424 17 17 0,000 0,03256781 0,05338985 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,03256781 0,05335182 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,03256781 0,05331385 ! retinoid metabolic process GO:0001523 22 17 0,000 0,03256781 0,05327593 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,03256781 0,05323806 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,03256781 0,05320025 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,03256781 0,05316249 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,03256781 0,05312479 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,03256781 0,05308714 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,03256781 0,05304954 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,03256781 0,053012 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,03256781 0,05297451 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,03256781 0,05293707 ! heme metabolic process GO:0042168 27 17 0,000 0,03256781 0,05289968 ! actin filament bundle formation GO:0051017 26 17 0,000 0,03256781 0,05286235 ! neuromuscular junction development GO:0007528 23 17 0,000 0,03256781 0,05282507 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,03256781 0,05278785 ! body fluid secretion GO:0007589 27 17 0,000 0,03256781 0,05275067 ! stem cell differentiation GO:0048863 36 17 0,000 0,03256781 0,05271355 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,03256781 0,05267648 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,03256781 0,05263946 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,03256781 0,0526025 ! sensory perception of pain GO:0019233 23 17 0,000 0,03256781 0,05256558 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,03256781 0,05252872 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,03256781 0,05249191 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,03256781 0,05245515 ! synaptogenesis GO:0007416 24 17 0,000 0,03256781 0,05241844 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,03256781 0,05238179 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,03256781 0,05234518 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,03256781 0,05230863 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,03256781 0,05227212 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,03256781 0,05223567 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,03256781 0,05219927 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,03256781 0,05216292 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,03256781 0,05212662 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03445116 0,05510268 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03445116 0,05506439 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03445116 0,05502615 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03445116 0,05498796 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03445116 0,05494983 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03445116 0,05491175 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03445116 0,05487372 ! axis specification GO:0009798 26 18 0,000 0,03445116 0,05483575 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03445116 0,05479783 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03445116 0,05475996 ! pancreas development GO:0031016 26 18 0,000 0,03445116 0,05472214 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,03445116 0,05468437 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03445116 0,05464666 ! response to retinoic acid GO:0032526 25 18 0,000 0,03445116 0,054609 ! pigmentation during development GO:0048066 31 18 0,000 0,03445116 0,05457139 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03445116 0,05453383 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,03445116 0,05449633 ! fucose metabolic process GO:0006004 26 18 0,000 0,03445116 0,05445887 ! response to fungus GO:0009620 19 18 0,000 0,03445116 0,05442147 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03445116 0,05438412 ! heart process GO:0003015 27 18 0,000 0,03445116 0,05434682 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03445116 0,05430957 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03445116 0,05427237 ! somitogenesis GO:0001756 24 18 0,000 0,03445116 0,05423522 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03445116 0,05419812 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03445116 0,05416108 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03445116 0,05412408 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03445116 0,05408714 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03445116 0,05405024 ! vitamin transport GO:0051180 24 18 0,000 0,03445116 0,0540134 ! hormone transport GO:0009914 27 18 0,000 0,03445116 0,05397661 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03445116 0,05393986 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03445116 0,05390317 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03445116 0,05386652 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03445116 0,05382993 ! cell-cell recognition GO:0009988 20 18 0,000 0,03445116 0,05379339 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03445116 0,05375689 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03445116 0,05372045 ! regulation of glucose import GO:0046324 21 18 0,000 0,03445116 0,05368405 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03445116 0,0536477 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03445116 0,05361141 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03445116 0,05357516 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03445116 0,05353896 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03633095 0,05642213 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03633095 0,05638406 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03633095 0,05634604 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03633095 0,05630807 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03633095 0,05627015 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03633095 0,05623228 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03633095 0,05619447 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03633095 0,0561567 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03633095 0,05611899 ! regeneration GO:0031099 32 19 0,000 0,03633095 0,05608133 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03633095 0,05604371 ! response to alkaloid GO:0043279 32 19 0,000 0,03633095 0,05600615 ! sensory perception of taste GO:0050909 23 19 0,000 0,03633095 0,05596864 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03633095 0,05593117 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03633095 0,05589376 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03633095 0,0558564 ! peroxisome organization GO:0007031 29 19 0,000 0,03633095 0,05581909 ! digestive system process GO:0022600 30 19 0,000 0,03633095 0,05578183 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03633095 0,05574461 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03633095 0,05570745 ! response to vitamin A GO:0033189 26 19 0,000 0,03633095 0,05567034 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03633095 0,05563327 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03633095 0,05559626 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03633095 0,05555929 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03633095 0,05552238 ! response to starvation GO:0042594 30 19 0,000 0,03633095 0,05548551 ! sex determination GO:0007530 29 19 0,000 0,03633095 0,05544869 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03633095 0,05541192 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03633095 0,0553752 ! cytolysis GO:0019835 20 19 0,000 0,03633095 0,05533853 ! renal system process GO:0003014 35 19 0,000 0,03633095 0,0553019 ! vasodilation GO:0042311 33 19 0,000 0,03633095 0,05526533 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03633095 0,0552288 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03633095 0,05519232 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03633095 0,05515589 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03633095 0,05511951 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03633095 0,05508317 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03633095 0,05504689 ! sarcomere organization GO:0045214 23 19 0,000 0,03633095 0,05501065 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03633095 0,05497446 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03633095 0,05493831 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03633095 0,05490222 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03633095 0,05486617 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03633095 0,05483017 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03633095 0,05479421 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03633095 0,05475831 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03633095 0,05472245 ! protein stabilization GO:0050821 26 19 0,000 0,03633095 0,05468663 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03820718 0,0574732 ! iron ion transport GO:0006826 37 20 0,000 0,03820718 0,05743564 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03820718 0,05739812 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03820718 0,05736065 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03820718 0,05732324 ! response to vitamin GO:0033273 29 20 0,000 0,03820718 0,05728587 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03820718 0,05724855 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03820718 0,05721128 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03820718 0,05717406 ! spinal cord development GO:0021510 31 20 0,000 0,03820718 0,05713688 ! response to ethanol GO:0045471 37 20 0,000 0,03820718 0,05709976 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03820718 0,05706268 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03820718 0,05702565 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03820718 0,05698867 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03820718 0,05695173 ! chromosome condensation GO:0030261 31 20 0,000 0,03820718 0,05691485 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03820718 0,05687801 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03820718 0,05684122 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03820718 0,05680448 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03820718 0,05676778 ! pallium development GO:0021543 38 20 0,000 0,03820718 0,05673113 ! DNA modification GO:0006304 28 20 0,000 0,03820718 0,05669453 ! collagen fibril organization GO:0030199 45 20 0,000 0,03820718 0,05665798 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03820718 0,05662147 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03820718 0,05658501 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03820718 0,0565486 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,03820718 0,05651223 ! collagen catabolic process GO:0030574 25 20 0,000 0,03820718 0,05647591 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03820718 0,05643964 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03820718 0,05640342 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03820718 0,05636724 ! actin filament-based movement GO:0030048 34 20 0,000 0,03820718 0,0563311 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,04007988 0,05905427 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,04007988 0,05901646 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,04007988 0,0589787 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,04007988 0,05894099 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,04007988 0,05890333 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,04007988 0,05886572 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,04007988 0,05882815 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,04007988 0,05879064 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,04007988 0,05875316 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,04007988 0,05871574 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,04007988 0,05867837 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,04007988 0,05864104 ! protein amino acid acylation GO:0043543 37 21 0,000 0,04007988 0,05860376 ! vesicle docking GO:0048278 27 21 0,000 0,04007988 0,05856653 ! phototransduction GO:0007602 25 21 0,000 0,04007988 0,05852934 ! dendrite development GO:0016358 35 21 0,000 0,04007988 0,05849221 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,04007988 0,05845511 ! ovarian follicle development GO:0001541 30 21 0,000 0,04007988 0,05841807 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,04007988 0,05838107 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,04007988 0,05834412 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,04007988 0,05830722 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,04007988 0,05827036 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,04007988 0,05823355 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,04007988 0,05819679 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,04007988 0,05816007 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,04007988 0,0581234 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,04007988 0,05808678 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,04007988 0,0580502 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,04007988 0,05801367 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,04007988 0,05797718 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,04007988 0,05794074 ! fatty acid transport GO:0015908 30 21 0,000 0,04007988 0,05790434 ! immunoglobulin production GO:0002377 33 21 0,000 0,04007988 0,05786799 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,04007988 0,05783169 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,04007988 0,05779543 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,04007988 0,05775922 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,04007988 0,05772305 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,04007988 0,05768693 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,04007988 0,05765085 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,04007988 0,05761482 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,04007988 0,05757884 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,04007988 0,05754289 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,04007988 0,057507 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,04007988 0,05747114 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,04007988 0,05743534 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,04194903 0,06007644 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,04194903 0,06003906 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,04194903 0,06000172 ! viral genome replication GO:0019079 29 22 0,000 0,04194903 0,05996443 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,04194903 0,05992719 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,04194903 0,05988999 ! leukocyte adhesion GO:0007159 38 22 0,000 0,04194903 0,05985283 ! molting cycle process GO:0022404 40 22 0,000 0,04194903 0,05981573 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,04194903 0,05977867 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,04194903 0,05974165 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,04194903 0,05970468 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,04194903 0,05966776 ! vasculogenesis GO:0001570 33 22 0,000 0,04194903 0,05963088 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,04194903 0,05959405 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,04194903 0,05955726 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,04194903 0,05952052 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,04194903 0,05948383 ! lysosome organization GO:0007040 37 22 0,000 0,04194903 0,05944718 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,04194903 0,05941057 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,04194903 0,05937401 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,04194903 0,0593375 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,04194903 0,05930103 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,04194903 0,0592646 ! membrane depolarization GO:0051899 35 22 0,000 0,04194903 0,05922822 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,04194903 0,05919188 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,04194903 0,05915559 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,04194903 0,05911934 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,04194903 0,05908314 ! blastocyst development GO:0001824 37 22 0,000 0,04194903 0,05904698 ! neural tube closure GO:0001843 33 22 0,000 0,04194903 0,05901087 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,04194903 0,0589748 ! protein tetramerization GO:0051262 39 22 0,000 0,04194903 0,05893877 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,04381465 0,0615224 ! neuron fate commitment GO:0048663 32 23 0,000 0,04381465 0,06148487 ! embryonic pattern specification GO:0009880 31 23 0,000 0,04381465 0,06144738 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,04381465 0,06140993 ! myelination GO:0042552 35 23 0,000 0,04381465 0,06137253 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,04381465 0,06133518 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,04381465 0,06129787 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,04381465 0,06126061 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,04381465 0,06122339 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,04381465 0,06118621 ! vesicle targeting GO:0006903 32 23 0,000 0,04381465 0,06114909 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,04381465 0,061112 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,04381465 0,06107497 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,04381465 0,06103797 ! interaction with host GO:0051701 37 23 0,000 0,04381465 0,06100103 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,04381465 0,06096412 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,04381465 0,06092726 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,04381465 0,06089045 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,04381465 0,06085368 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,04381465 0,06081696 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,04381465 0,06078027 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,04381465 0,06074364 ! cell fate determination GO:0001709 45 23 0,000 0,04381465 0,06070705 ! pentose metabolic process GO:0019321 31 23 0,000 0,04381465 0,0606705 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,04381465 0,06063399 ! spermatid development GO:0007286 33 23 0,000 0,04381465 0,06059753 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,04381465 0,06056111 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,04381465 0,06052474 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,04381465 0,06048841 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,04381465 0,06045213 ! telomere organization GO:0032200 32 23 0,000 0,04381465 0,06041588 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,04381465 0,06037969 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,04381465 0,06034353 ! regulation of amine transport GO:0051952 38 23 0,000 0,04381465 0,06030742 ! liver development GO:0001889 40 23 0,000 0,04381465 0,06027135 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04567674 0,06279529 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04567674 0,06275777 ! initiation of viral infection GO:0019059 42 24 0,000 0,04567674 0,06272031 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04567674 0,06268288 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04567674 0,0626455 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04567674 0,06260817 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04567674 0,06257088 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,04567674 0,06253364 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04567674 0,06249644 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04567674 0,06245928 ! vacuole organization GO:0007033 39 24 0,000 0,04567674 0,06242217 ! receptor metabolic process GO:0043112 37 24 0,000 0,04567674 0,0623851 ! neural crest cell development GO:0014032 39 24 0,000 0,04567674 0,06234808 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,04567674 0,0623111 ! primary neural tube formation GO:0014020 35 24 0,000 0,04567674 0,06227416 ! negative regulation of cell development GO:0010721 56 24 0,000 0,04567674 0,06223727 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04567674 0,06220042 ! base-excision repair GO:0006284 31 24 0,000 0,04567674 0,06216362 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04567674 0,06212686 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,04567674 0,06209014 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,04567674 0,06205346 ! glutathione metabolic process GO:0006749 29 24 0,000 0,04567674 0,06201683 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,04567674 0,06198024 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04567674 0,0619437 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04567674 0,0619072 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04753532 0,06438824 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04753532 0,06435034 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04753532 0,06431249 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04753532 0,06427468 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04753532 0,06423692 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04753532 0,0641992 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,04753532 0,06416152 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,04753532 0,06412389 ! peptide transport GO:0015833 43 25 0,000 0,04753532 0,0640863 ! male gonad development GO:0008584 33 25 0,000 0,04753532 0,06404876 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04753532 0,06401126 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04753532 0,06397381 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04753532 0,06393639 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04753532 0,06389903 ! phospholipid transport GO:0015914 35 25 0,000 0,04753532 0,0638617 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04753532 0,06382442 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04753532 0,06378718 ! detection of light stimulus GO:0009583 30 25 0,000 0,04753532 0,06374999 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,04753532 0,06371284 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04753532 0,06367573 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04753532 0,06363867 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04753532 0,06360165 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04939038 0,06604527 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,04939038 0,0660069 ! translational initiation GO:0006413 43 26 0,000 0,04939038 0,06596857 ! regulation of pH GO:0006885 36 26 0,000 0,04939038 0,06593028 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,04939038 0,06589204 ! circadian rhythm GO:0007623 42 26 0,000 0,04939038 0,06585384 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04939038 0,06581569 ! post-embryonic development GO:0009791 42 26 0,000 0,04939038 0,06577758 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04939038 0,06573951 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04939038 0,06570149 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,04939038 0,06566351 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,04939038 0,06562558 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04939038 0,06558769 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04939038 0,06554984 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04939038 0,06551204 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,05124193 0,06792879 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,05124193 0,06788966 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,05124193 0,06785057 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,05124193 0,06781153 ! membrane docking GO:0022406 39 27 0,000 0,05124193 0,06777254 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,05124193 0,06773359 ! catechol metabolic process GO:0009712 43 27 0,000 0,05124193 0,06769469 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,05124193 0,06765583 ! acute-phase response GO:0006953 42 27 0,000 0,05124193 0,06761701 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,05124193 0,06757824 ! myofibril assembly GO:0030239 36 27 0,000 0,05124193 0,06753951 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,05124193 0,06750083 ! response to ionizing radiation GO:0010212 47 27 0,000 0,05124193 0,06746219 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,05124193 0,0674236 ! natural killer cell activation GO:0030101 35 27 0,000 0,05124193 0,06738505 ! lipid oxidation GO:0034440 38 27 0,000 0,05124193 0,06734654 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,05124193 0,06730808 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,05124193 0,06726966 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,05124193 0,06723129 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,05124193 0,06719296 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 0,000 0,05124193 0,06715467 ! gene silencing GO:0016458 41 27 0,000 0,05124193 0,06711643 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,05308999 0,06949742 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,05308999 0,06945789 ! phenol metabolic process GO:0018958 44 28 0,000 0,05308999 0,0694184 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,05308999 0,06937896 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,05308999 0,06933956 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,05308999 0,06930021 ! cell junction assembly GO:0034329 56 28 0,000 0,05308999 0,0692609 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,05308999 0,06922164 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,05308999 0,06918242 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,05308999 0,06914324 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,05308999 0,06910411 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,05308999 0,06906503 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,05308999 0,06902599 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,05308999 0,06898699 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,05308999 0,06894804 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,05308999 0,06890913 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,05308999 0,06887026 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,05308999 0,06883144 ! mesoderm formation GO:0001707 46 28 0,000 0,05308999 0,06879266 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,05308999 0,06875392 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,05308999 0,06871523 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,05308999 0,06867659 ! ensheathment of neurons GO:0007272 43 28 0,000 0,05308999 0,06863798 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,05308999 0,06859942 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,05308999 0,0685609 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,05308999 0,06852243 ! neural tube formation GO:0001841 41 28 0,000 0,05308999 0,068484 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,05308999 0,06844561 ! placenta development GO:0001890 37 28 0,000 0,05308999 0,06840727 ! regulation of B cell activation GO:0050864 42 28 0,000 0,05308999 0,06836896 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,05493455 0,07070479 ! regulation of innate immune response GO:0045088 38 29 0,000 0,05493455 0,07066524 ! ovulation cycle process GO:0022602 41 29 0,000 0,05493455 0,07062574 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,05493455 0,07058629 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,05493455 0,07054688 ! mismatch repair GO:0006298 34 29 0,000 0,05493455 0,07050751 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,05493455 0,07046819 ! muscle cell development GO:0055001 38 29 0,000 0,05493455 0,07042891 ! formation of primary germ layer GO:0001704 48 29 0,000 0,05493455 0,07038967 ! telencephalon development GO:0021537 52 29 0,000 0,05493455 0,07035048 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,05493455 0,07031133 ! tissue homeostasis GO:0001894 42 29 0,000 0,05493455 0,07027222 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,05677562 0,07258695 ! collagen metabolic process GO:0032963 40 30 0,000 0,05677562 0,07254662 ! organic anion transport GO:0015711 51 30 0,000 0,05677562 0,07250634 ! cholesterol transport GO:0030301 46 30 0,000 0,05677562 0,07246611 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,05677562 0,07242591 ! spliceosome assembly GO:0000245 49 30 0,000 0,05677562 0,07238577 ! spindle organization GO:0007051 37 30 0,000 0,05677562 0,07234566 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,05677562 0,0723056 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,05677562 0,07226559 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,05677562 0,07222562 ! ceramide metabolic process GO:0006672 43 30 0,000 0,05677562 0,07218569 ! ovulation cycle GO:0042698 43 30 0,000 0,05677562 0,07214581 ! hindbrain development GO:0030902 45 30 0,000 0,05677562 0,07210598 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,05677562 0,07206618 ! adult locomotory behavior GO:0008344 47 30 0,000 0,05677562 0,07202643 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,05677562 0,07198673 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,05677562 0,07194706 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,05677562 0,07190745 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,05677562 0,07186787 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,05861321 0,07415312 ! negative regulation of secretion GO:0051048 49 31 0,000 0,05861321 0,07411236 ! mammary gland development GO:0030879 57 31 0,000 0,05861321 0,07407164 ! glial cell differentiation GO:0010001 55 31 0,000 0,05861321 0,07403096 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,05861321 0,07399033 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,05861321 0,07394974 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,05861321 0,0739092 ! odontogenesis GO:0042476 50 31 0,000 0,05861321 0,0738687 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,05861321 0,07382825 ! segmentation GO:0035282 41 31 0,000 0,05861321 0,07378784 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,05861321 0,07374747 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,05861321 0,07370715 ! metanephros development GO:0001656 58 31 0,000 0,05861321 0,07366687 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,05861321 0,07362664 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,05861321 0,07358645 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,05861321 0,07354631 ! cell fate specification GO:0001708 37 31 0,000 0,05861321 0,07350621 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,05861321 0,07346615 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,05861321 0,07342613 ! RNA modification GO:0009451 40 31 0,000 0,05861321 0,07338616 ! regulation of muscle development GO:0048634 48 32 0,000 0,06044732 0,07564137 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,06044732 0,07560024 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,06044732 0,07555916 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,06044732 0,07551811 ! meiosis I GO:0007127 52 32 0,000 0,06044732 0,07547712 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,06044732 0,07543616 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,06044732 0,07539525 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,06044732 0,07535439 ! peripheral nervous system development GO:0007422 53 32 0,000 0,06044732 0,07531357 ! regulation of protein stability GO:0031647 48 32 0,000 0,06044732 0,07527279 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,06044732 0,07523206 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,06044732 0,07519137 ! cytokine production GO:0001816 44 32 0,000 0,06044732 0,07515073 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,06044732 0,07511013 ! vesicle localization GO:0051648 47 32 0,000 0,06044732 0,07506957 ! RNA export from nucleus GO:0006405 44 33 0,000 0,06227797 0,07730131 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,06227797 0,07725962 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,06227797 0,07721797 ! sister chromatid segregation GO:0000819 46 33 0,000 0,06227797 0,07717637 ! ear morphogenesis GO:0042471 42 33 0,000 0,06227797 0,07713481 ! actomyosin structure organization GO:0031032 43 33 0,000 0,06227797 0,07709329 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,06227797 0,07705182 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,06227797 0,07701039 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,06227797 0,07696901 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,06227797 0,07692768 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,06227797 0,07688638 ! female gonad development GO:0008585 49 33 0,000 0,06227797 0,07684514 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,06227797 0,07680393 ! positive regulation of cell development GO:0010720 54 33 0,000 0,06227797 0,07676277 ! lipid homeostasis GO:0055088 55 33 0,000 0,06227797 0,07672166 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,06227797 0,07668059 ! regulation of proteolysis GO:0030162 50 33 0,000 0,06227797 0,07663956 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,06227797 0,07659857 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,06227797 0,07655763 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,06227797 0,07651674 ! cytokinesis GO:0000910 52 33 0,000 0,06227797 0,07647589 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,06227797 0,07643508 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,06410516 0,07863566 ! mRNA catabolic process GO:0006402 48 34 0,000 0,06410516 0,07859374 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,06410516 0,07855187 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,06410516 0,07851004 ! feeding behavior GO:0007631 45 34 0,000 0,06410516 0,07846826 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,06410516 0,07842652 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,06410516 0,07838483 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,06410516 0,07834318 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,06410516 0,07830157 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,06410516 0,07826001 ! neuron migration GO:0001764 46 34 0,000 0,06410516 0,07821849 ! female gamete generation GO:0007292 43 34 0,000 0,06410516 0,07817702 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,06410516 0,07813559 ! aerobic respiration GO:0009060 47 34 0,000 0,06410516 0,07809421 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,06410516 0,07805286 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,06410516 0,07801157 ! embryonic organ development GO:0048568 45 34 0,000 0,06410516 0,07797031 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,06410516 0,0779291 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,06592889 0,08010377 ! Notch signaling pathway GO:0007219 56 35 0,000 0,06592889 0,08006148 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,06592889 0,08001923 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,06592889 0,07997702 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,06592889 0,07993486 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,06592889 0,07989275 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,06592889 0,07985068 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,06592889 0,07980865 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,06592889 0,07976667 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,06592889 0,07972473 ! glycogen metabolic process GO:0005977 48 35 0,000 0,06592889 0,07968284 ! pigment metabolic process GO:0042440 61 35 0,000 0,06592889 0,07964099 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,06592889 0,07959918 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,06592889 0,07955742 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,06774916 0,08171111 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,06774916 0,08166828 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,06774916 0,0816255 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,06774916 0,08158276 ! negative regulation of binding GO:0051100 58 36 0,000 0,06774916 0,08154007 ! organic ether metabolic process GO:0018904 46 36 0,000 0,06774916 0,08149743 ! tissue remodeling GO:0048771 62 36 0,000 0,06774916 0,08145482 ! neural tube development GO:0021915 50 36 0,000 0,06774916 0,08141227 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,06774916 0,08136975 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,06774916 0,08132729 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,06774916 0,08128486 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,06774916 0,08124248 ! glucan metabolic process GO:0044042 49 36 0,000 0,06774916 0,08120015 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,069566 0,08333427 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,069566 0,08329089 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,069566 0,08324756 ! ion transmembrane transport GO:0034220 56 37 0,000 0,069566 0,08320427 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,069566 0,08316102 ! regulation of protein secretion GO:0050708 51 37 0,000 0,069566 0,08311782 ! amino acid activation GO:0043038 52 37 0,000 0,069566 0,08307466 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,069566 0,08303155 ! gliogenesis GO:0042063 71 38 0,000 0,0713794 0,08515177 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,0713794 0,08510763 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,0713794 0,08506353 ! mesenchymal cell development GO:0014031 64 38 0,000 0,0713794 0,08501948 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,0713794 0,08497548 ! maintenance of location in cell GO:0051651 69 38 0,000 0,0713794 0,08493152 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,07318937 0,0870401 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,07318937 0,08699512 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,07318937 0,08695018 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,07318937 0,08690529 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,07318937 0,08686045 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,07318937 0,08681565 ! male sex differentiation GO:0046661 53 39 0,000 0,07318937 0,0867709 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,07318937 0,0867262 ! chromatin remodeling GO:0006338 68 39 0,000 0,07318937 0,08668154 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,07318937 0,08663693 ! JNK cascade GO:0007254 54 39 0,000 0,07318937 0,08659236 ! developmental growth GO:0048589 62 39 0,000 0,07318937 0,08654784 ! synapse organization GO:0050808 55 39 0,000 0,07318937 0,08650337 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,07499591 0,08859302 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,07499591 0,08854754 ! regulation of tube size GO:0035150 60 40 0,000 0,07499591 0,08850211 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,07499591 0,08845672 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,07499591 0,08841138 ! peptide metabolic process GO:0006518 56 40 0,000 0,07499591 0,08836609 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,07499591 0,08832084 ! inner ear development GO:0048839 57 40 0,000 0,07499591 0,08827564 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,07499591 0,08823049 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,07499591 0,08818538 ! double-strand break repair GO:0006302 67 40 0,000 0,07499591 0,08814032 ! B cell differentiation GO:0030183 62 40 0,000 0,07499591 0,0880953 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,07499591 0,08805033 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,07499591 0,08800541 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,07499591 0,08796053 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,07679904 0,09002946 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,07679904 0,08998359 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,07679904 0,08993778 ! glucose transport GO:0015758 52 41 0,000 0,07679904 0,08989201 ! endosome transport GO:0016197 71 41 0,000 0,07679904 0,08984628 ! striated muscle contraction GO:0006941 62 41 0,000 0,07679904 0,08980061 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,07679904 0,08975498 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,07679904 0,08970939 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,07679904 0,08966386 ! biopolymer methylation GO:0043414 62 41 0,000 0,07679904 0,08961836 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,07679904 0,08957292 ! mitochondrial transport GO:0006839 60 42 0,000 0,07859876 0,09162551 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,07859876 0,0915791 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,07859876 0,09153273 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,07859876 0,09148641 ! cellular component disassembly GO:0022411 64 42 0,000 0,07859876 0,09144013 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,07859876 0,0913939 ! hexose transport GO:0008645 54 42 0,000 0,07859876 0,09134772 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,07859876 0,09130159 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,07859876 0,0912555 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,07859876 0,09120946 ! excretion GO:0007588 63 42 0,000 0,07859876 0,09116346 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,07859876 0,09111751 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,07859876 0,09107161 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,07859876 0,09102575 ! regulation of cell shape GO:0008360 78 42 0,000 0,07859876 0,09097994 ! positive regulation of binding GO:0051099 59 43 0,000 0,08039507 0,0930124 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,08039507 0,09296564 ! leukocyte migration GO:0050900 60 43 0,000 0,08039507 0,09291892 ! neuromuscular process GO:0050905 79 43 0,000 0,08039507 0,09287225 ! activation of caspase activity GO:0006919 65 43 0,000 0,08039507 0,09282563 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,08039507 0,09277905 ! tRNA processing GO:0008033 49 43 0,000 0,08039507 0,09273252 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,08039507 0,09268604 ! response to insulin stimulus GO:0032868 63 43 0,000 0,08039507 0,09263961 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,08039507 0,09259322 ! methylation GO:0032259 64 43 0,000 0,08039507 0,09254687 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,08218798 0,09456346 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,08218798 0,09451617 ! glycolysis GO:0006096 53 44 0,000 0,08218798 0,09446894 ! regulation of action potential GO:0001508 71 44 0,000 0,08218798 0,09442175 ! regulation of ion transport GO:0043269 57 44 0,000 0,08218798 0,09437461 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,08218798 0,09432752 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,08218798 0,09428047 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,08218798 0,09423347 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,08218798 0,09418652 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,08218798 0,09413962 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,08218798 0,09409276 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,08218798 0,09404594 ! RNA catabolic process GO:0006401 64 45 0,000 0,08397749 0,09604587 ! positive regulation of defense response GO:0031349 59 45 0,000 0,08397749 0,09599813 ! regulation of translational initiation GO:0006446 64 45 0,000 0,08397749 0,09595044 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,08397749 0,0959028 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,08397749 0,09585521 ! cell recognition GO:0008037 58 45 0,000 0,08397749 0,09580766 ! cell maturation GO:0048469 60 45 0,000 0,08397749 0,09576016 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,08397749 0,0957127 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,08576363 0,09770002 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,08576363 0,09765165 ! cell redox homeostasis GO:0045454 63 46 0,000 0,08576363 0,09760333 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,08576363 0,09755506 ! regulation of ossification GO:0030278 71 46 0,000 0,08576363 0,09750684 ! histone modification GO:0016570 68 46 0,000 0,08576363 0,09745867 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,08576363 0,09741054 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,08754638 0,09938631 ! viral infectious cycle GO:0019058 71 47 0,000 0,08754638 0,09933728 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,08754638 0,0992883 ! endocrine system development GO:0035270 83 47 0,000 0,08754638 0,09923936 ! covalent chromatin modification GO:0016569 75 47 0,000 0,08754638 0,09919048 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,08754638 0,09914164 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,08754638 0,09909285 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,08754638 0,0990441 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,08754638 0,09899541 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 0,000 0,08754638 0,09894676 ! chloride transport GO:0006821 67 48 0,000 0,08932575 0,10090827 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,08932575 0,10085873 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,08932575 0,10080924 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,08932575 0,1007598 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,08932575 0,10071041 ! gastrulation GO:0007369 73 48 0,000 0,08932575 0,10066106 ! heart morphogenesis GO:0003007 65 48 0,000 0,08932575 0,10061177 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,08932575 0,10056252 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,08932575 0,10051332 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,08932575 0,10046417 ! regulation of endocytosis GO:0030100 63 48 0,000 0,08932575 0,10041507 ! nuclear export GO:0051168 69 48 0,000 0,08932575 0,10036601 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,08932575 0,10031701 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,09110176 0,10226162 ! sensory perception of smell GO:0007608 61 49 0,000 0,09110176 0,10221173 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,09110176 0,1021619 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,09110176 0,10211211 ! RNA elongation GO:0006354 62 49 0,000 0,09110176 0,10206237 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,09110176 0,10201268 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,09110176 0,10196304 ! germ cell development GO:0007281 68 49 0,000 0,09110176 0,10191345 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,09110176 0,1018639 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,09110176 0,10181441 ! cartilage development GO:0051216 70 49 0,000 0,09110176 0,10176496 ! maintenance of location GO:0051235 84 49 0,000 0,09110176 0,10171556 ! regulation of actin filament length GO:0030832 72 50 0,000 0,09287441 0,10364441 ! ear development GO:0043583 72 50 0,000 0,09287441 0,10359415 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,09287441 0,10354393 ! membrane fusion GO:0006944 80 50 0,000 0,09287441 0,10349377 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,09287441 0,10344365 ! lipid modification GO:0030258 73 50 0,000 0,09287441 0,10339358 ! positive regulation of growth GO:0045927 67 50 0,000 0,09287441 0,10334356 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,09287441 0,10329359 ! proton transport GO:0015992 75 50 0,000 0,09287441 0,10324366 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,09287441 0,10319379 ! positive regulation of secretion GO:0051047 71 51 0,000 0,0946437 0,10510889 ! hydrogen transport GO:0006818 77 51 0,000 0,0946437 0,10505816 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,0946437 0,10500748 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,0946437 0,10495685 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,0946437 0,10490627 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,0946437 0,10485573 ! adult behavior GO:0030534 80 51 0,000 0,0946437 0,10480525 ! transition metal ion transport GO:0000041 74 52 0,000 0,09640964 0,10670942 ! regulation of cellular component size GO:0032535 74 52 0,000 0,09640964 0,10665809 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,09640964 0,10660681 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,09640964 0,10655558 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,09640964 0,1065044 ! establishment of organelle localization GO:0051656 85 52 0,000 0,09640964 0,10645327 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,09817224 0,10834748 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,09817224 0,10829551 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,09817224 0,1082436 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,09817224 0,10819173 ! kidney development GO:0001822 90 53 0,000 0,09817224 0,10813991 ! single fertilization GO:0007338 59 53 0,000 0,09817224 0,10808815 ! amino acid transport GO:0006865 84 54 0,000 0,0999315 0,10997246 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,0999315 0,10991987 ! regulation of mitosis GO:0007088 84 54 0,000 0,0999315 0,10986732 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,0999315 0,10981483 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,0999315 0,10976239 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,0999315 0,10970999 ! DNA catabolic process GO:0006308 67 54 0,000 0,0999315 0,10965765 ! detection of external stimulus GO:0009581 66 54 0,000 0,0999315 0,10960536 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,0999315 0,10955312 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,0999315 0,10950092 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,0999315 0,10944878 ! exocytosis GO:0006887 74 55 0,000 0,10168742 0,11131893 ! mesoderm development GO:0007498 76 55 0,000 0,10168742 0,11126597 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,10168742 0,11121307 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,10168742 0,11116021 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,10344003 0,11302236 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,10344003 0,11296869 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,10518931 0,11482459 ! carbohydrate transport GO:0008643 74 57 0,000 0,10518931 0,11477012 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,10518931 0,1147157 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,10518931 0,11466134 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,10518931 0,11460702 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,10518931 0,11455276 ! camera-type eye development GO:0043010 88 57 0,000 0,10518931 0,11449854 ! secondary metabolic process GO:0019748 84 57 0,000 0,10518931 0,11444438 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,10518931 0,11439027 ! developmental maturation GO:0021700 75 57 0,000 0,10518931 0,11433621 ! gonad development GO:0008406 79 57 0,000 0,10518931 0,1142822 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,10693529 0,11612425 ! viral reproductive process GO:0022415 87 58 0,000 0,10693529 0,11606945 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,10693529 0,1160147 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,10693529 0,11596 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,10693529 0,11590535 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,10867795 0,11773871 ! lung development GO:0030324 94 59 0,000 0,10867795 0,11768328 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,10867795 0,1176279 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,10867795 0,11757257 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,11041732 0,11939813 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,11041732 0,11934202 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,11041732 0,11928597 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,11041732 0,11922996 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,11041732 0,11917401 ! regulation of heart contraction GO:0008016 91 60 0,000 0,11041732 0,11911812 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,11041732 0,11906227 ! fertilization GO:0009566 68 60 0,000 0,11041732 0,11900648 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,11041732 0,11895074 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,11215338 0,12076441 ! meiosis GO:0007126 96 61 0,000 0,11215338 0,1207079 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,11215338 0,12065144 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,11215338 0,12059504 ! urogenital system development GO:0001655 101 61 0,000 0,11215338 0,12053868 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,11215338 0,12048238 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,11215338 0,12042614 ! extracellular matrix organization GO:0030198 103 61 0,000 0,11215338 0,12036994 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,11215338 0,1203138 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,11215338 0,12025771 ! amine catabolic process GO:0009310 90 62 0,000 0,11388617 0,1220588 ! neurotransmitter transport GO:0006836 81 62 0,000 0,11388617 0,12200195 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,11388617 0,12194515 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,11388617 0,12188841 ! respiratory tube development GO:0030323 99 62 0,000 0,11388617 0,12183171 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,11388617 0,12177507 ! meiotic cell cycle GO:0051321 97 62 0,000 0,11388617 0,12171849 ! organelle localization GO:0051640 96 62 0,000 0,11388617 0,12166195 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,11561567 0,1234522 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,11561567 0,12339491 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,11561567 0,12333768 ! viral reproduction GO:0016032 92 63 0,000 0,11561567 0,1232805 ! regulation of lipase activity GO:0060191 109 63 0,000 0,11561567 0,12322337 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,11734189 0,12500525 ! negative regulation of cell size GO:0045792 108 64 0,000 0,11734189 0,12494738 ! appendage morphogenesis GO:0035107 93 64 0,000 0,11734189 0,12488956 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,11734189 0,1248318 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,11734189 0,12477408 ! hexose catabolic process GO:0019320 82 64 0,000 0,11734189 0,12471642 ! respiratory system development GO:0060541 100 64 0,000 0,11734189 0,12465882 ! adaptive immune response GO:0002250 94 64 0,000 0,11734189 0,12460127 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,11906484 0,12637246 ! regulation of caspase activity GO:0043281 97 65 0,000 0,11906484 0,12631417 ! appendage development GO:0048736 94 65 0,000 0,11906484 0,12625594 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,11906484 0,12619776 ! defense response to bacterium GO:0042742 73 65 0,000 0,11906484 0,12613963 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,11906484 0,12608155 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,11906484 0,12602353 ! activation of immune response GO:0002253 83 65 0,000 0,11906484 0,12596556 ! protein oligomerization GO:0051259 100 65 0,000 0,11906484 0,12590765 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,12078453 0,12766747 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,12078453 0,12760882 ! antigen processing and presentation GO:0019882 96 66 0,000 0,12078453 0,12755024 ! axon guidance GO:0007411 99 66 0,000 0,12078453 0,1274917 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,12078453 0,12743322 ! regulation of immune effector process GO:0002697 101 66 0,000 0,12078453 0,12737479 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,12250096 0,12912566 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,12250096 0,12906651 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,12250096 0,12900742 ! acute inflammatory response GO:0002526 92 68 0,000 0,12421413 0,13075172 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,12421413 0,1306919 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,12421413 0,13063215 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,12421413 0,13057244 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,12421413 0,13051279 ! rhythmic process GO:0048511 105 68 0,000 0,12421413 0,1304532 ! inorganic anion transport GO:0015698 93 68 0,000 0,12421413 0,13039366 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,12592406 0,13212835 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,12592406 0,1320681 ! response to drug GO:0042493 108 69 0,000 0,12592406 0,1320079 ! humoral immune response GO:0006959 86 70 0,000 0,12763075 0,1337361 ! amine transport GO:0015837 101 70 0,000 0,12763075 0,1336752 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,12763075 0,13361435 ! regulation of catabolic process GO:0009894 106 70 0,000 0,12763075 0,13355356 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,12933421 0,13527452 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,12933421 0,13521303 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,12933421 0,1351516 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,12933421 0,13509022 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,12933421 0,1350289 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,13103443 0,13674192 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,13103443 0,13667991 ! regulation of blood pressure GO:0008217 107 73 0,000 0,13273144 0,13838726 ! tube morphogenesis GO:0035239 118 73 0,000 0,13273144 0,13832456 ! mitochondrion organization GO:0007005 104 73 0,000 0,13273144 0,13826191 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,13273144 0,13819932 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,13442522 0,13989955 ! digestion GO:0007586 97 74 0,000 0,13442522 0,13983628 ! protein import into nucleus GO:0006606 118 74 0,000 0,13442522 0,13977306 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,13442522 0,1397099 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,13442522 0,1396468 ! blood coagulation GO:0007596 116 75 0,000 0,1361158 0,1413392 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,1361158 0,14127542 ! response to nutrient GO:0007584 104 75 0,000 0,1361158 0,1412117 ! nuclear import GO:0051170 121 75 0,000 0,1361158 0,14114803 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,1361158 0,14108442 ! amine biosynthetic process GO:0009309 97 76 0,000 0,13780317 0,14276905 ! tRNA metabolic process GO:0006399 95 76 0,000 0,13780317 0,14270477 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,13780317 0,14264054 ! regulation of protein transport GO:0051223 114 76 0,000 0,13780317 0,14257638 GO:0070201|regulation of establishment of protein localization, ! cholesterol metabolic process GO:0008203 109 77 0,000 0,13948734 0,14425399 ! regulation of DNA binding GO:0051101 119 77 0,000 0,13948734 0,14418916 ! gland development GO:0048732 148 77 0,000 0,13948734 0,14412439 ! sex differentiation GO:0007548 105 77 0,000 0,13948734 0,14405967 ! protein ubiquitination GO:0016567 125 77 0,000 0,13948734 0,14399501 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,13948734 0,14393041 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,14116832 0,14559961 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,14284611 0,14726403 ! T cell activation GO:0042110 134 79 0,000 0,14284611 0,14719805 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,14284611 0,14713213 ! chromatin assembly GO:0031497 102 80 0,000 0,14452072 0,14879036 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,14452072 0,14872378 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,14452072 0,14865727 ! forebrain development GO:0030900 131 80 0,000 0,14452072 0,14859082 ! hemostasis GO:0007599 125 81 0,000 0,14619215 0,15024216 ! mRNA transport GO:0051028 121 81 0,000 0,14619215 0,15017506 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,14619215 0,15010802 ! vitamin metabolic process GO:0006766 103 81 0,000 0,14619215 0,15004103 ! detection of stimulus GO:0051606 108 82 0,000 0,14786042 0,15168553 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,14952552 0,15332532 ! regulation of defense response GO:0031347 117 84 0,000 0,15118746 0,15496041 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,15118746 0,15489139 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,15118746 0,15482242 ! sterol metabolic process GO:0016125 120 84 0,000 0,15118746 0,15475352 ! rRNA metabolic process GO:0016072 107 85 0,000 0,15284625 0,15638184 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,15284625 0,15631231 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,15284625 0,15624283 ! regulation of protein localization GO:0032880 132 85 0,000 0,15284625 0,15617342 ! regulation of membrane potential GO:0042391 128 85 0,000 0,15284625 0,15610407 ! nucleosome organization GO:0034728 114 87 0,000 0,1561544 0,15941195 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,1561544 0,15934122 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,1561544 0,15927056 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,1561544 0,15919996 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,1561544 0,15912943 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,1561544 0,15905895 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,15780376 0,16066784 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,15780376 0,16059675 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,15780376 0,16052572 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,15780376 0,16045476 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,15780376 0,16038385 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,15945 0,16198543 ! reproductive developmental process GO:0003006 127 89 0,000 0,15945 0,16191391 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,15945 0,16184246 ! regulation of T cell activation GO:0050863 128 89 0,000 0,15945 0,16177107 ! leukocyte differentiation GO:0002521 143 90 0,000 0,16109312 0,16336604 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,16109312 0,16329404 ! hormone metabolic process GO:0042445 121 90 0,000 0,16109312 0,1632221 ! RNA localization GO:0006403 135 91 0,000 0,16273312 0,16481117 ! ATP metabolic process GO:0046034 137 91 0,000 0,16273312 0,16473863 ! response to virus GO:0009615 122 91 0,000 0,16273312 0,16466615 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,16437 0,16624934 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,16437 0,16617626 ! cell fate commitment GO:0045165 141 92 0,000 0,16437 0,16610325 ! positive regulation of immune response GO:0050778 121 92 0,000 0,16437 0,1660303 ! DNA recombination GO:0006310 146 92 0,000 0,16437 0,16595742 ! sulfur metabolic process GO:0006790 118 92 0,000 0,16437 0,1658846 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,16600378 0,16745995 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,16600378 0,16738654 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,16600378 0,16731319 ! electron transport chain GO:0022900 123 94 0,000 0,16763446 0,16888272 ! regulation of binding GO:0051098 151 95 0,000 0,16926204 0,17044777 ! carboxylic acid transport GO:0046942 147 95 0,000 0,16926204 0,17037317 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,17088654 0,17193309 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,17088654 0,17185791 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,17088654 0,1717828 ! protein maturation GO:0051604 129 96 0,000 0,17088654 0,17170775 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,17250795 0,17326126 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,17250795 0,17318563 ! calcium ion transport GO:0006816 167 99 0,000 0,17574154 0,17635495 ! extracellular structure organization GO:0043062 156 99 0,000 0,17574154 0,17627804 ! protein import GO:0017038 156 99 0,000 0,17574154 0,1762012 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,17735374 0,17774013 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,17735374 0,17766272 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,17735374 0,17758537 ! divalent metal ion transport GO:0070838 171 100 0,000 0,17735374 0,17750809 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,17735374 0,17743088 ! protein localization in organelle GO:0033365 161 100 0,000 0,17735374 0,17735374