pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/7057-8-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 9 5 2,000 1,646E-08 4,022E-05 GO:0019405|alditol catabolic process, ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 2,000 1,646E-08 2,011E-05 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 9,196E-08 7,489E-05 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 2,000 3,6E-07 2,199E-04 ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 4,677E-07 2,285E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 6,998E-07 2,849E-04 ! fructose metabolic process GO:0006000 25 16 2,000 9,134E-07 3,188E-04 ! regulation of endothelial cell migration GO:0010594 45 19 2,000 1,577E-06 4,814E-04 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 2,000 2,16E-06 5,864E-04 ! positive regulation of locomotion GO:0040017 44 22 2,000 2,499E-06 6,105E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 45 23 2,000 2,872E-06 6,378E-04 ! regulation of behavior GO:0050795 48 25 2,000 3,723E-06 7,58E-04 ! osteoblast differentiation GO:0001649 63 26 2,000 4,205E-06 7,902E-04 ! regulation of blood coagulation GO:0030193 46 26 2,000 4,205E-06 7,338E-04 ! alditol metabolic process GO:0019400 44 26 2,000 4,205E-06 6,849E-04 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 4,727E-06 7,217E-04 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 5,012E-06 7,202E-04 ! sperm motility GO:0030317 37 28 2,000 5,29E-06 7,179E-04 ! regulation of coagulation GO:0050818 52 30 2,000 6,544E-06 8,415E-04 ! hexose biosynthetic process GO:0019319 53 32 2,000 7,982E-06 9,75E-04 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 1,145E-05 1,332E-03 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 2,000 1,245E-05 1,383E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! apoptotic cell clearance GO:0043277 23 5 1,000 1,426E-05 1,515E-03 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 1,000 1,426E-05 1,452E-03 ! positive regulation of blood coagulation GO:0030194 12 5 1,000 1,426E-05 1,394E-03 ! positive regulation of macrophage activation GO:0043032 12 5 1,000 1,426E-05 1,34E-03 ! negative regulation of fibrinolysis GO:0051918 11 5 1,000 1,426E-05 1,29E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,426E-05 1,244E-03 ! alcohol biosynthetic process GO:0046165 65 42 2,000 1,832E-05 1,543E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 2,11E-05 1,718E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 2,138E-05 1,685E-03 GO:0046530|photoreceptor cell differentiation, ! negative regulation of platelet activation GO:0010544 9 6 1,000 2,138E-05 1,632E-03 GO:0010543|regulation of platelet activation, ! positive regulation of coagulation GO:0050820 13 6 1,000 2,138E-05 1,583E-03 ! polyol metabolic process GO:0019751 77 45 2,000 2,259E-05 1,623E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 2,414E-05 1,685E-03 ! negative regulation of cell migration GO:0030336 122 46 2,000 2,414E-05 1,638E-03 ! response to calcium ion GO:0051592 94 49 2,000 2,923E-05 1,93E-03 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 1,000 2,991E-05 1,923E-03 ! negative regulation of focal adhesion formation GO:0051895 21 7 1,000 2,991E-05 1,873E-03 ! regulation of lipid transport GO:0032368 14 7 1,000 2,991E-05 1,826E-03 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 1,000 2,991E-05 1,782E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 3,984E-05 2,318E-03 ! regulation of focal adhesion formation GO:0051893 23 8 1,000 3,984E-05 2,264E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 1,000 3,984E-05 2,212E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 1,000 3,984E-05 2,163E-03 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of Rac protein signal transduction GO:0035020 18 8 1,000 3,984E-05 2,116E-03 ! negative regulation of organic acid transport GO:0032891 13 8 1,000 3,984E-05 2,071E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 1,000 3,984E-05 2,028E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 1,000 3,984E-05 1,986E-03 ! negative regulation of cell motion GO:0051271 142 55 2,000 4,141E-05 2,023E-03 ! positive regulation of cell migration GO:0030335 137 58 2,000 4,858E-05 2,327E-03 ! regulation of macrophage activation GO:0043030 17 9 1,000 5,119E-05 2,405E-03 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 1,000 6,393E-05 2,947E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 6,393E-05 2,892E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 6,393E-05 2,84E-03 ! phagocytosis, engulfment GO:0006911 33 10 1,000 6,393E-05 2,789E-03 ! regulation of fibrinolysis GO:0051917 20 10 1,000 6,393E-05 2,74E-03 ! positive regulation of cell motion GO:0051272 157 65 2,000 6,836E-05 2,879E-03 ! Golgi vesicle budding GO:0048194 26 11 1,000 7,808E-05 3,233E-03 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 7,808E-05 3,179E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 7,808E-05 3,127E-03 ! substrate-bound cell migration GO:0006929 14 11 1,000 7,808E-05 3,077E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 7,808E-05 3,028E-03 ! regulation of organic acid transport GO:0032890 19 11 1,000 7,808E-05 2,981E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 7,808E-05 2,935E-03 ! negative regulation of endothelial cell migration GO:0010596 26 12 1,000 9,363E-05 3,466E-03 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 9,363E-05 3,414E-03 ! regulation of leukocyte migration GO:0002685 29 12 1,000 9,363E-05 3,364E-03 ! establishment of cell polarity GO:0030010 21 12 1,000 9,363E-05 3,315E-03 ! negative regulation of lipid metabolic process GO:0045833 20 13 1,000 1,106E-04 3,859E-03 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 1,106E-04 3,804E-03 ! response to steroid hormone stimulus GO:0048545 147 79 2,000 1,223E-04 4,15E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 1,000 1,289E-04 4,314E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! response to hypoxia GO:0001666 178 81 2,000 1,317E-04 4,349E-03 ! positive regulation of phosphorylation GO:0042327 149 81 2,000 1,317E-04 4,291E-03 ! regulation of adenylate cyclase activity GO:0045761 165 83 2,000 1,416E-04 4,553E-03 ! response to oxygen levels GO:0070482 183 83 2,000 1,416E-04 4,494E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 1,416E-04 4,436E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 2,000 1,468E-04 4,538E-03 ! response to hexose stimulus GO:0009746 25 15 1,000 1,486E-04 4,538E-03 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! regulation of cyclase activity GO:0031279 168 85 2,000 1,52E-04 4,584E-03 ! regulation of cAMP biosynthetic process GO:0030817 173 86 2,000 1,574E-04 4,688E-03 ! regulation of lyase activity GO:0051339 169 86 2,000 1,574E-04 4,632E-03 ! alcohol catabolic process GO:0046164 142 87 2,000 1,628E-04 4,736E-03 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 1,742E-04 5,006E-03 ! response to inorganic substance GO:0010035 173 90 2,000 1,8E-04 5,114E-03 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 2,000 1,86E-04 5,223E-03 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 2,000 1,86E-04 5,164E-03 ! bone development GO:0060348 206 92 2,000 1,921E-04 5,274E-03 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 1,922E-04 5,217E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 1,922E-04 5,16E-03 ! membrane budding GO:0006900 42 17 1,000 1,922E-04 5,103E-03 ! negative regulation of blood coagulation GO:0030195 25 17 1,000 1,922E-04 5,049E-03 ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 2,047E-04 5,321E-03 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 2,112E-04 5,432E-03 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 2,112E-04 5,375E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 2,315E-04 5,831E-03 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 2,315E-04 5,771E-03 ! positive regulation of translation GO:0045727 31 19 1,000 2,413E-04 5,954E-03 ! regulation of lipid biosynthetic process GO:0046890 28 19 1,000 2,413E-04 5,894E-03 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 2,413E-04 5,836E-03 ! peptide cross-linking GO:0018149 39 19 1,000 2,413E-04 5,779E-03 ! visual learning GO:0008542 38 19 1,000 2,413E-04 5,723E-03 ! positive regulation of angiogenesis GO:0045766 50 20 1,000 2,679E-04 6,293E-03 ! response to carbohydrate stimulus GO:0009743 33 20 1,000 2,679E-04 6,233E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 2,679E-04 6,174E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! cell-cell junction organization GO:0045216 43 20 1,000 2,679E-04 6,116E-03 ! negative regulation of coagulation GO:0050819 30 20 1,000 2,679E-04 6,06E-03 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 2,959E-04 6,631E-03 ! cell aging GO:0007569 48 22 1,000 3,252E-04 7,222E-03 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 3,252E-04 7,157E-03 ! positive regulation of DNA replication GO:0045740 44 23 1,000 3,559E-04 7,763E-03 ! visual behavior GO:0007632 46 23 1,000 3,559E-04 7,694E-03 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 3,559E-04 7,626E-03 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 3,559E-04 7,56E-03 ! negative regulation of cytokine production GO:0001818 41 23 1,000 3,559E-04 7,495E-03 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 3,879E-04 8,1E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 4,213E-04 8,723E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 4,561E-04 9,364E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 5,297E-04 0,01078332 ! negative regulation of protein modification process GO:0031400 66 28 1,000 5,297E-04 0,0106942 ! fat cell differentiation GO:0045444 57 28 1,000 5,297E-04 0,01060654 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 5,685E-04 0,01129092 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 5,685E-04 0,01119986 ! eye morphogenesis GO:0048592 65 31 1,000 6,501E-04 0,01270529 ! response to heat GO:0009408 54 31 1,000 6,501E-04 0,01260445 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 8,293E-04 0,01595223 ! protein targeting to membrane GO:0006612 75 36 1,000 8,774E-04 0,01674578 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 9,268E-04 0,01755198 ! cell junction organization GO:0034330 96 37 1,000 9,268E-04 0,01741697 ! negative regulation of cell activation GO:0050866 69 37 1,000 9,268E-04 0,01728401 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 9,776E-04 0,01809213 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 9,776E-04 0,0179561 ! learning GO:0007612 82 40 1,000 1,083E-03 0,01974385 ! establishment or maintenance of cell polarity GO:0007163 96 41 1,000 1,138E-03 0,0205868 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 1,251E-03 0,0224694 ! striated muscle cell differentiation GO:0051146 91 43 1,000 1,251E-03 0,02230539 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 1,309E-03 0,02318043 ! phagocytosis GO:0006909 105 44 1,000 1,309E-03 0,02301367 ! keratinocyte differentiation GO:0030216 81 45 1,000 1,369E-03 0,02389371 ! cell growth GO:0016049 90 46 1,000 1,43E-03 0,02478362 ! positive regulation of cell cycle GO:0045787 96 48 1,000 1,557E-03 0,02677924 ! epidermal cell differentiation GO:0009913 87 50 1,000 1,688E-03 0,02883444 ! positive regulation of cytokine production GO:0001819 94 50 1,000 1,688E-03 0,02863421 ! response to temperature stimulus GO:0009266 84 51 1,000 1,755E-03 0,02957473 ! negative regulation of immune system process GO:0002683 101 51 1,000 1,755E-03 0,02937217 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 1,824E-03 0,030316 ! vesicle organization GO:0016050 127 53 1,000 1,894E-03 0,03126802 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 1,894E-03 0,03105817 ! regulation of angiogenesis GO:0045765 125 54 1,000 1,966E-03 0,03201315 ! response to UV GO:0009411 120 55 1,000 2,038E-03 0,03297591 ! regulation of DNA replication GO:0006275 105 56 1,000 2,112E-03 0,03394624 ! aging GO:0007568 112 58 1,000 2,264E-03 0,03614352 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 2,919E-03 0,04631212 ! activation of MAPK activity GO:0000187 124 67 1,000 3,007E-03 0,04739283 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 3,096E-03 0,04847884 ! cell projection assembly GO:0030031 138 68 1,000 3,096E-03 0,04817006 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 3,186E-03 0,04925628 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 3,186E-03 0,04894649 ! actin filament organization GO:0007015 167 72 1,000 3,463E-03 0,05287305 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 3,463E-03 0,05254465 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 3,463E-03 0,0522203 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 3,654E-03 0,0547603 ! eye development GO:0001654 155 75 1,000 3,751E-03 0,05587476 ! learning or memory GO:0007611 161 76 1,000 3,849E-03 0,05699348 ! positive regulation of ligase activity GO:0051351 130 77 1,000 3,949E-03 0,05811634 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 4,152E-03 0,06073554 ! regulation of synaptic transmission GO:0050804 159 79 1,000 4,152E-03 0,06037402 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 4,255E-03 0,0615086 ! muscle cell differentiation GO:0042692 178 81 1,000 4,359E-03 0,06264688 ! regulation of ligase activity GO:0051340 147 84 1,000 4,68E-03 0,06685569 ! negative regulation of transport GO:0051051 164 85 1,000 4,789E-03 0,06801658 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 4,789E-03 0,06762343 ! positive regulation of cell activation GO:0050867 161 86 1,000 4,899E-03 0,06878301 GO:0002696|positive regulation of leukocyte activation, ! cellular respiration GO:0045333 143 88 1,000 5,123E-03 0,07151761 ! regulation of neurological system process GO:0031644 175 89 1,000 5,237E-03 0,07269042 ! positive regulation of protein modification process GO:0031401 156 90 1,000 5,352E-03 0,07386599 ! response to unfolded protein GO:0006986 139 90 1,000 5,352E-03 0,07345101 ! regulation of cell adhesion GO:0030155 241 92 1,000 5,585E-03 0,07622505 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 5,703E-03 0,07740838 GO:0010498|proteasomal protein catabolic process, ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 6,035E-03 0,08144992 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 6,035E-03 0,08100239 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 6,035E-03 0,08055975 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,035E-03 0,08012193 ! positive regulation of helicase activity GO:0051096 12 5 0,000 6,035E-03 0,07968884 ! neuron fate determination GO:0048664 7 5 0,000 6,035E-03 0,0792604 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,035E-03 0,07883655 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 6,035E-03 0,07841721 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 6,035E-03 0,0780023 ! polyol transport GO:0015791 12 5 0,000 6,035E-03 0,07759176 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,035E-03 0,07718552 ! response to superoxide GO:0000303 10 5 0,000 6,035E-03 0,07678351 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,035E-03 0,07638567 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 6,035E-03 0,07599193 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 6,035E-03 0,07560223 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,035E-03 0,0752165 ! female meiosis GO:0007143 10 5 0,000 6,035E-03 0,07483469 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,035E-03 0,07445674 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,035E-03 0,07408259 ! hypothalamus development GO:0021854 9 5 0,000 6,035E-03 0,07371217 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 6,035E-03 0,07334545 ! cobalt ion transport GO:0006824 11 5 0,000 6,035E-03 0,07298235 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 6,035E-03 0,07262283 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 6,035E-03 0,07226684 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,035E-03 0,07191432 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,035E-03 0,07156522 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 6,035E-03 0,07121949 ! embryonic camera-type eye development GO:0031076 12 5 0,000 6,035E-03 0,07087709 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,035E-03 0,07053797 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,035E-03 0,07020207 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 6,035E-03 0,06986936 ! transposition GO:0032196 9 5 0,000 6,035E-03 0,06953979 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 6,035E-03 0,06921331 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 6,035E-03 0,06888988 ! negative chemotaxis GO:0050919 16 5 0,000 6,035E-03 0,06856946 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,035E-03 0,06825201 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,035E-03 0,06793749 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 6,035E-03 0,06762585 ! behavioral response to pain GO:0048266 10 5 0,000 6,035E-03 0,06731705 ! clathrin coat assembly GO:0048268 15 5 0,000 6,035E-03 0,06701107 ! Notch receptor processing GO:0007220 11 5 0,000 6,035E-03 0,06670785 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,035E-03 0,06640736 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 6,035E-03 0,06610957 ! micturition GO:0060073 9 5 0,000 6,035E-03 0,06581444 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,035E-03 0,06552193 ! copulation GO:0007620 9 5 0,000 6,035E-03 0,06523201 ! glial cell fate commitment GO:0021781 14 5 0,000 6,035E-03 0,06494465 ! protein maturation by protein folding GO:0022417 14 5 0,000 6,035E-03 0,0646598 ! bioluminescence GO:0008218 9 5 0,000 6,035E-03 0,06437744 ! spermidine metabolic process GO:0008216 7 5 0,000 6,035E-03 0,06409754 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,035E-03 0,06382006 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,035E-03 0,06354498 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,035E-03 0,06327225 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 6,035E-03 0,06300186 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,035E-03 0,06273376 ! grooming behavior GO:0007625 6 5 0,000 6,035E-03 0,06246794 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 6,035E-03 0,06220437 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,035E-03 0,061943 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 6,035E-03 0,06168383 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,035E-03 0,06142681 ! response to protozoan GO:0001562 13 5 0,000 6,035E-03 0,06117193 ! positive regulation of glycolysis GO:0045821 13 5 0,000 6,035E-03 0,06091915 ! lymph vessel development GO:0001945 10 5 0,000 6,035E-03 0,06066846 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 6,035E-03 0,06041981 ! endochondral ossification GO:0001958 17 5 0,000 6,035E-03 0,0601732 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,035E-03 0,0599286 ! single strand break repair GO:0000012 8 5 0,000 6,035E-03 0,05968597 ! parathyroid gland development GO:0060017 14 5 0,000 6,035E-03 0,0594453 ! anagen GO:0042640 7 5 0,000 6,035E-03 0,05920657 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,035E-03 0,05896974 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,035E-03 0,0587348 ! cytokine secretion GO:0050663 15 5 0,000 6,035E-03 0,05850173 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 6,035E-03 0,05827049 ! ceramide catabolic process GO:0046514 7 5 0,000 6,035E-03 0,05804108 ! skeletal myofibril assembly GO:0014866 12 5 0,000 6,035E-03 0,05781347 ! smooth muscle tissue development GO:0048745 32 5 0,000 6,035E-03 0,05758764 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,035E-03 0,05736356 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,035E-03 0,05714122 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,035E-03 0,0569206 ! cardiac muscle fiber development GO:0048739 12 5 0,000 6,035E-03 0,05670167 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,035E-03 0,05648442 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 6,035E-03 0,05626884 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,035E-03 0,05605489 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 6,035E-03 0,05584256 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,035E-03 0,05563183 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,035E-03 0,05542269 ! glycine biosynthetic process GO:0006545 7 5 0,000 6,035E-03 0,05521511 ! microvillus organization GO:0032528 8 5 0,000 6,035E-03 0,05500908 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 6,035E-03 0,05480459 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 6,035E-03 0,05460161 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 6,035E-03 0,05440013 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 6,035E-03 0,05420013 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 6,035E-03 0,05400159 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 6,035E-03 0,05380451 ! polyol biosynthetic process GO:0046173 6 5 0,000 6,035E-03 0,05360885 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 6,035E-03 0,05341462 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,035E-03 0,05322179 ! muscle cell migration GO:0014812 8 5 0,000 6,035E-03 0,05303034 ! mitochondrial fission GO:0000266 8 5 0,000 6,035E-03 0,05284027 ! sister chromatid cohesion GO:0007062 15 5 0,000 6,035E-03 0,05265155 ! response to tumor necrosis factor GO:0034612 10 5 0,000 6,035E-03 0,05246418 ! mRNA transcription GO:0009299 10 5 0,000 6,035E-03 0,05227814 ! nerve growth factor processing GO:0032455 9 5 0,000 6,035E-03 0,05209341 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 6,035E-03 0,05190998 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 6,035E-03 0,05172784 ! anaerobic glycolysis GO:0019642 6 5 0,000 6,035E-03 0,05154697 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,035E-03 0,05136737 ! monocyte activation GO:0042117 10 5 0,000 6,035E-03 0,05118901 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,035E-03 0,05101189 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,035E-03 0,05083598 ! response to food GO:0032094 6 5 0,000 6,035E-03 0,05066129 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,035E-03 0,05048779 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,035E-03 0,05031548 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 6,035E-03 0,05014434 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,035E-03 0,04997436 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 6,035E-03 0,04980552 ! forebrain neuron development GO:0021884 13 5 0,000 6,035E-03 0,04963783 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,035E-03 0,04947126 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 6,035E-03 0,0493058 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 6,035E-03 0,04914145 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,035E-03 0,04897819 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,035E-03 0,04881601 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 6,035E-03 0,0486549 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,035E-03 0,04849485 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 6,035E-03 0,04833585 ! lipid glycosylation GO:0030259 7 5 0,000 6,035E-03 0,04817789 ! nucleobase transport GO:0015851 6 5 0,000 6,035E-03 0,04802096 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,035E-03 0,04786505 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 6,035E-03 0,04771014 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 6,035E-03 0,04755624 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 6,035E-03 0,04740333 ! basic amino acid transport GO:0015802 12 5 0,000 6,035E-03 0,04725139 ! cellular glucose homeostasis GO:0001678 6 5 0,000 6,035E-03 0,04710043 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 6,035E-03 0,04695043 ! actin nucleation GO:0045010 11 5 0,000 6,035E-03 0,04680138 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,035E-03 0,04665327 ! depurination GO:0045007 5 5 0,000 6,035E-03 0,0465061 ! depyrimidination GO:0045008 10 5 0,000 6,035E-03 0,04635986 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,035E-03 0,04621453 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,035E-03 0,04607011 ! G2/M transition checkpoint GO:0031576 8 5 0,000 6,035E-03 0,04592659 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,035E-03 0,04578396 ! zinc ion homeostasis GO:0055069 9 5 0,000 6,035E-03 0,04564221 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 6,035E-03 0,04550134 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 6,035E-03 0,04536134 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,035E-03 0,04522219 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,035E-03 0,0450839 ! activated T cell proliferation GO:0050798 16 5 0,000 6,035E-03 0,04494645 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,035E-03 0,04480983 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 6,035E-03 0,04467404 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,035E-03 0,04453908 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,035E-03 0,04440492 ! gamma-delta T cell activation GO:0046629 6 5 0,000 6,035E-03 0,04427158 ! response to arsenic GO:0046685 11 5 0,000 6,035E-03 0,04413903 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 6,035E-03 0,04400727 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,035E-03 0,04387629 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 6,035E-03 0,0437461 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 6,035E-03 0,04361667 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 6,035E-03 0,04348801 ! response to mercury ion GO:0046689 8 5 0,000 6,035E-03 0,0433601 ! response to cadmium ion GO:0046686 7 5 0,000 6,035E-03 0,04323295 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 6,035E-03 0,04310653 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 6,035E-03 0,04298086 ! bile acid biosynthetic process GO:0006699 7 5 0,000 6,035E-03 0,04285592 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,035E-03 0,04273169 ! ganglioside catabolic process GO:0006689 12 5 0,000 6,035E-03 0,04260819 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,035E-03 0,0424854 ! decidualization GO:0046697 11 5 0,000 6,035E-03 0,04236332 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 6,035E-03 0,04224193 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 6,035E-03 0,04212124 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 6,035E-03 0,04200124 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 6,035E-03 0,04188192 ! embryonic cleavage GO:0040016 6 5 0,000 6,035E-03 0,04176327 ! peroxisome fission GO:0016559 5 5 0,000 6,035E-03 0,0416453 ! histone demethylation GO:0016577 13 5 0,000 6,035E-03 0,04152799 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 6,035E-03 0,04141133 ! mitotic recombination GO:0006312 9 5 0,000 6,035E-03 0,04129534 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 6,035E-03 0,04117999 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,035E-03 0,04106528 ! metaphase plate congression GO:0051310 7 5 0,000 6,035E-03 0,04095121 ! regulation of sterol transport GO:0032371 7 5 0,000 6,035E-03 0,04083777 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,035E-03 0,04072496 ! enteric nervous system development GO:0048484 8 5 0,000 6,035E-03 0,04061277 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 6,035E-03 0,04050119 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 6,035E-03 0,04039023 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 6,035E-03 0,04027988 ! muscle cell proliferation GO:0033002 12 5 0,000 6,035E-03 0,04017012 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,035E-03 0,04006096 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 6,035E-03 0,0399524 ! B cell homeostasis GO:0001782 13 5 0,000 6,035E-03 0,03984442 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 6,035E-03 0,03973702 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,035E-03 0,0396302 ! metaphase GO:0051323 11 5 0,000 6,035E-03 0,03952395 ! melatonin biosynthetic process GO:0030187 7 5 0,000 6,035E-03 0,03941827 GO:0030186|melatonin metabolic process, ! cellular response to nutrient GO:0031670 8 5 0,000 6,035E-03 0,03931316 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 6,035E-03 0,0392086 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 6,035E-03 0,0391046 ! regulation of hair follicle development GO:0051797 10 5 0,000 6,035E-03 0,03900115 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 6,035E-03 0,03889824 ! response to redox state GO:0051775 6 5 0,000 6,035E-03 0,03879588 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 6,035E-03 0,03869405 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 6,035E-03 0,03859276 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,035E-03 0,038492 ! brown fat cell differentiation GO:0050873 7 5 0,000 6,035E-03 0,03839176 ! regulation of telomerase activity GO:0051972 7 5 0,000 6,035E-03 0,03829204 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,035E-03 0,03819284 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 6,035E-03 0,03809415 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,035E-03 0,03799597 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 6,035E-03 0,03789829 ! striatum development GO:0021756 14 5 0,000 6,035E-03 0,03780111 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 6,035E-03 0,03770444 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,035E-03 0,03760825 ! glial cell migration GO:0008347 10 5 0,000 6,035E-03 0,03751256 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,035E-03 0,03741735 ! neural plate morphogenesis GO:0001839 7 5 0,000 6,035E-03 0,03732262 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 6,035E-03 0,03722837 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,035E-03 0,0371346 ! T cell activation during immune response GO:0002286 9 5 0,000 6,035E-03 0,03704129 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,035E-03 0,03694846 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 6,035E-03 0,03685609 ! neuroprotection GO:0043526 8 5 0,000 6,035E-03 0,03676418 ! regulation of sensory perception GO:0051931 8 5 0,000 6,035E-03 0,03667272 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,035E-03 0,03658172 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 6,035E-03 0,03649118 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 6,035E-03 0,03640107 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,035E-03 0,03631142 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 6,035E-03 0,0362222 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,035E-03 0,03613342 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 6,035E-03 0,03604507 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 6,035E-03 0,03595716 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 6,035E-03 0,03586967 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,035E-03 0,03578261 ! spindle assembly GO:0051225 6 5 0,000 6,035E-03 0,03569597 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,035E-03 0,03560975 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,035E-03 0,03552394 ! protein palmitoylation GO:0018345 12 5 0,000 6,035E-03 0,03543855 ! drug metabolic process GO:0017144 7 5 0,000 6,035E-03 0,03535356 ! stem cell division GO:0017145 11 5 0,000 6,035E-03 0,03526898 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,035E-03 0,03518481 ! organ regeneration GO:0031100 7 5 0,000 6,035E-03 0,03510104 ! carnitine metabolic process GO:0009437 8 5 0,000 6,035E-03 0,03501766 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,035E-03 0,03493468 ! response to protein stimulus GO:0051789 158 96 1,000 6,065E-03 0,0350307 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 6,188E-03 0,03565659 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,237E-03 0,04160112 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,237E-03 0,04150347 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 7,237E-03 0,04140627 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 7,237E-03 0,04130953 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 7,237E-03 0,04121323 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 7,237E-03 0,04111739 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 7,237E-03 0,04102199 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,237E-03 0,04092703 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 7,237E-03 0,04083251 ! response to oxygen radical GO:0000305 11 6 0,000 7,237E-03 0,04073843 ! positive regulation of axon extension GO:0045773 13 6 0,000 7,237E-03 0,04064477 ! myoblast cell fate commitment GO:0048625 18 6 0,000 7,237E-03 0,04055155 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 7,237E-03 0,04045876 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 7,237E-03 0,04036639 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,237E-03 0,04027443 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,237E-03 0,0401829 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 7,237E-03 0,04009178 ! forebrain regionalization GO:0021871 9 6 0,000 7,237E-03 0,04000108 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,237E-03 0,03991078 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,237E-03 0,03982089 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 7,237E-03 0,03973141 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,237E-03 0,03964232 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 7,237E-03 0,03955364 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 7,237E-03 0,03946535 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,237E-03 0,03937745 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 7,237E-03 0,03928995 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 7,237E-03 0,03920283 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,237E-03 0,0391161 ! malate metabolic process GO:0006108 13 6 0,000 7,237E-03 0,03902975 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 7,237E-03 0,03894378 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 7,237E-03 0,03885819 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 7,237E-03 0,03877298 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 7,237E-03 0,03868813 ! protein refolding GO:0042026 15 6 0,000 7,237E-03 0,03860366 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,237E-03 0,03851956 ! opsonization GO:0008228 8 6 0,000 7,237E-03 0,03843582 ! mating behavior GO:0007617 7 6 0,000 7,237E-03 0,03835244 ! erythrocyte maturation GO:0043249 8 6 0,000 7,237E-03 0,03826943 ! embryonic hemopoiesis GO:0035162 16 6 0,000 7,237E-03 0,03818677 ! protein amino acid dealkylation GO:0008214 15 6 0,000 7,237E-03 0,03810448 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 7,237E-03 0,03802253 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,237E-03 0,03794094 ! response to interferon-gamma GO:0034341 16 6 0,000 7,237E-03 0,03785969 ! toxin metabolic process GO:0009404 11 6 0,000 7,237E-03 0,0377788 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,237E-03 0,03769824 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 7,237E-03 0,03761804 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 7,237E-03 0,03753817 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 7,237E-03 0,03745864 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 7,237E-03 0,03737944 ! cGMP-mediated signaling GO:0019934 14 6 0,000 7,237E-03 0,03730058 ! dorsal spinal cord development GO:0021516 10 6 0,000 7,237E-03 0,03722206 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,237E-03 0,03714386 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 7,237E-03 0,03706599 ! thymic T cell selection GO:0045061 16 6 0,000 7,237E-03 0,03698845 ! sphingoid catabolic process GO:0046521 8 6 0,000 7,237E-03 0,03691123 ! protein lipoylation GO:0009249 10 6 0,000 7,237E-03 0,03683433 ! transepithelial chloride transport GO:0030321 12 6 0,000 7,237E-03 0,03675775 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 7,237E-03 0,03668149 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,237E-03 0,03660554 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 7,237E-03 0,03652991 ! glutamate catabolic process GO:0006538 12 6 0,000 7,237E-03 0,03645459 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 7,237E-03 0,03637958 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 7,237E-03 0,03630488 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 7,237E-03 0,03623049 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,237E-03 0,03615639 ! hyperosmotic response GO:0006972 10 6 0,000 7,237E-03 0,03608261 ! L-serine biosynthetic process GO:0006564 7 6 0,000 7,237E-03 0,03600912 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 7,237E-03 0,03593593 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 7,237E-03 0,03586304 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,237E-03 0,03579044 ! urea metabolic process GO:0019627 7 6 0,000 7,237E-03 0,03571813 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,237E-03 0,03564612 ! neutrophil activation GO:0042119 7 6 0,000 7,237E-03 0,0355744 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,237E-03 0,03550297 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 7,237E-03 0,03543182 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,237E-03 0,03536095 ! paraxial mesoderm development GO:0048339 16 6 0,000 7,237E-03 0,03529037 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 7,237E-03 0,03522007 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,237E-03 0,03515005 ! neuron apoptosis GO:0051402 15 6 0,000 7,237E-03 0,03508031 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 7,237E-03 0,03501085 ! T cell mediated immunity GO:0002456 17 6 0,000 7,237E-03 0,03494165 ! folic acid transport GO:0015884 14 6 0,000 7,237E-03 0,03487274 ! carnitine transport GO:0015879 10 6 0,000 7,237E-03 0,03480409 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,237E-03 0,03473571 ! positive regulation of exocytosis GO:0045921 11 6 0,000 7,237E-03 0,0346676 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 7,237E-03 0,03459976 ! early endosome to late endosome transport GO:0045022 16 6 0,000 7,237E-03 0,03453218 ! 5S class rRNA transcription GO:0042791 13 6 0,000 7,237E-03 0,03446487 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 7,237E-03 0,03439781 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 7,237E-03 0,03433102 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 7,237E-03 0,03426449 ! sodium ion homeostasis GO:0055078 12 6 0,000 7,237E-03 0,03419821 ! establishment of spindle localization GO:0051293 16 6 0,000 7,237E-03 0,03413219 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 7,237E-03 0,03406643 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,237E-03 0,03400092 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 7,237E-03 0,03393566 ! response to UV-C GO:0010225 14 6 0,000 7,237E-03 0,03387065 ! astrocyte development GO:0014002 16 6 0,000 7,237E-03 0,03380588 ! protein targeting to lysosome GO:0006622 12 6 0,000 7,237E-03 0,03374137 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,237E-03 0,0336771 ! interaction with symbiont GO:0051702 14 6 0,000 7,237E-03 0,03361307 ! regulation of dendrite development GO:0050773 16 6 0,000 7,237E-03 0,03354929 ! peptidyl-arginine modification GO:0018195 13 6 0,000 7,237E-03 0,03348575 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 7,237E-03 0,03342245 ! response to copper ion GO:0046688 10 6 0,000 7,237E-03 0,03335939 ! response to exogenous dsRNA GO:0043330 13 6 0,000 7,237E-03 0,03329657 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 7,237E-03 0,03323398 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,237E-03 0,03317163 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 7,237E-03 0,03310951 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,237E-03 0,03304762 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 7,237E-03 0,03298596 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,237E-03 0,03292454 ! nucleoside catabolic process GO:0009164 10 6 0,000 7,237E-03 0,03286334 ! hair follicle maturation GO:0048820 8 6 0,000 7,237E-03 0,03280237 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,237E-03 0,03274162 ! Schwann cell development GO:0014044 15 6 0,000 7,237E-03 0,0326811 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 7,237E-03 0,03262081 ! response to pheromone GO:0019236 6 6 0,000 7,237E-03 0,03256073 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 7,237E-03 0,03250088 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 7,237E-03 0,03244124 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 7,237E-03 0,03238183 ! base conversion or substitution editing GO:0016553 6 6 0,000 7,237E-03 0,03232263 ! subpallium development GO:0021544 15 6 0,000 7,237E-03 0,03226364 ! neural tube patterning GO:0021532 8 6 0,000 7,237E-03 0,03220488 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 7,237E-03 0,03214632 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 7,237E-03 0,03208798 ! maintenance of organ identity GO:0048496 9 6 0,000 7,237E-03 0,03202985 ! G2 phase GO:0051319 16 6 0,000 7,237E-03 0,03197193 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 7,237E-03 0,03191422 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 7,237E-03 0,03185671 ! oxygen homeostasis GO:0032364 10 6 0,000 7,237E-03 0,03179942 ! establishment of planar polarity GO:0001736 7 6 0,000 7,237E-03 0,03174233 ! regulation of mast cell activation GO:0033003 13 6 0,000 7,237E-03 0,03168544 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,237E-03 0,03162876 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 7,237E-03 0,03157228 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,237E-03 0,031516 ! receptor internalization GO:0031623 11 6 0,000 7,237E-03 0,03145992 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 7,237E-03 0,03140404 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 7,237E-03 0,03134836 ! neutrophil homeostasis GO:0001780 11 6 0,000 7,237E-03 0,03129288 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,237E-03 0,03123759 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 7,237E-03 0,0311825 ! protein deubiquitination GO:0016579 16 6 0,000 7,237E-03 0,0311276 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 7,237E-03 0,03107289 ! protein destabilization GO:0031648 9 6 0,000 7,237E-03 0,03101838 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 7,237E-03 0,03096406 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,237E-03 0,03090992 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 7,237E-03 0,03085598 ! regulation of viral transcription GO:0046782 11 6 0,000 7,237E-03 0,03080222 ! progesterone metabolic process GO:0042448 12 6 0,000 7,237E-03 0,03074866 ! negative regulation of axon extension GO:0030517 24 6 0,000 7,237E-03 0,03069527 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 7,237E-03 0,03064207 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 7,237E-03 0,03058906 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,237E-03 0,03053623 ! determination of adult lifespan GO:0008340 17 6 0,000 7,237E-03 0,03048358 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 7,237E-03 0,03043111 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 7,237E-03 0,03037883 ! neural plate development GO:0001840 9 6 0,000 7,237E-03 0,03032672 ! catecholamine transport GO:0051937 9 6 0,000 7,237E-03 0,03027479 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 7,237E-03 0,03022304 ! sensory cilium assembly GO:0035058 10 6 0,000 7,237E-03 0,03017146 ! organ or tissue specific immune response GO:0002251 8 6 0,000 7,237E-03 0,03012006 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 7,237E-03 0,03006884 ! maternal placenta development GO:0001893 12 6 0,000 7,237E-03 0,03001779 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 7,237E-03 0,02996691 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,237E-03 0,0299162 ! negative regulation of B cell activation GO:0050869 14 6 0,000 7,237E-03 0,02986567 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 7,237E-03 0,02981531 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 7,237E-03 0,02976511 ! cellular anion homeostasis GO:0030002 11 6 0,000 7,237E-03 0,02971509 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 8,438E-03 0,034589 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 8,438E-03 0,03453107 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 8,438E-03 0,03447332 ! behavioral response to cocaine GO:0048148 14 7 0,000 8,438E-03 0,03441577 ! regulation of helicase activity GO:0051095 16 7 0,000 8,438E-03 0,03435841 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 8,438E-03 0,03430124 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 8,438E-03 0,03424426 ! sleep GO:0030431 16 7 0,000 8,438E-03 0,03418747 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 8,438E-03 0,03413087 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 8,438E-03 0,03407446 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 8,438E-03 0,03401823 ! prostate gland development GO:0030850 14 7 0,000 8,438E-03 0,03396219 ! nucleotide-sugar transport GO:0015780 11 7 0,000 8,438E-03 0,03390633 ! synaptonemal complex assembly GO:0007130 10 7 0,000 8,438E-03 0,03385065 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 8,438E-03 0,03379516 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 8,438E-03 0,03373985 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,438E-03 0,03368472 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 8,438E-03 0,03362977 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 8,438E-03 0,03357499 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 8,438E-03 0,0335204 ! SMAD protein complex assembly GO:0007183 13 7 0,000 8,438E-03 0,03346598 ! glycolipid transport GO:0046836 11 7 0,000 8,438E-03 0,03341174 ! protein amino acid sulfation GO:0006477 10 7 0,000 8,438E-03 0,03335768 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 8,438E-03 0,03330379 ! neuron adhesion GO:0007158 14 7 0,000 8,438E-03 0,03325008 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 8,438E-03 0,03319653 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 8,438E-03 0,03314316 ! establishment of tissue polarity GO:0007164 8 7 0,000 8,438E-03 0,03308996 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 8,438E-03 0,03303693 ! mRNA stabilization GO:0048255 18 7 0,000 8,438E-03 0,03298407 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 8,438E-03 0,03293138 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 8,438E-03 0,03287886 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 8,438E-03 0,03282651 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 8,438E-03 0,03277432 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 8,438E-03 0,0327223 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 8,438E-03 0,03267044 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 8,438E-03 0,03261874 ! lipoprotein transport GO:0042953 14 7 0,000 8,438E-03 0,03256721 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 8,438E-03 0,03251585 ! rhythmic behavior GO:0007622 17 7 0,000 8,438E-03 0,03246464 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 8,438E-03 0,0324136 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 8,438E-03 0,03236271 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 8,438E-03 0,03231199 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 8,438E-03 0,03226142 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 8,438E-03 0,03221101 ! regulation of odontogenesis GO:0042481 14 7 0,000 8,438E-03 0,03216076 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 8,438E-03 0,03211066 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 8,438E-03 0,03206073 ! mechanosensory behavior GO:0007638 16 7 0,000 8,438E-03 0,03201094 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 8,438E-03 0,03196131 ! positive regulation of isotype switching GO:0045830 17 7 0,000 8,438E-03 0,03191184 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 8,438E-03 0,03186251 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 8,438E-03 0,03181334 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,438E-03 0,03176432 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,438E-03 0,03171546 ! spinal cord patterning GO:0021511 14 7 0,000 8,438E-03 0,03166674 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 8,438E-03 0,03161817 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 8,438E-03 0,03156975 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 8,438E-03 0,03152148 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 8,438E-03 0,03147335 ! adrenal gland development GO:0030325 17 7 0,000 8,438E-03 0,03142538 ! cysteine metabolic process GO:0006534 13 7 0,000 8,438E-03 0,03137754 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 8,438E-03 0,03132986 ! ovulation GO:0030728 10 7 0,000 8,438E-03 0,03128232 ! adenohypophysis development GO:0021984 11 7 0,000 8,438E-03 0,03123492 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 8,438E-03 0,03118766 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 8,438E-03 0,03114055 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 21 7 0,000 8,438E-03 0,03109358 ! proline biosynthetic process GO:0006561 10 7 0,000 8,438E-03 0,03104676 ! tryptophan metabolic process GO:0006568 11 7 0,000 8,438E-03 0,03100007 ! thyroid hormone generation GO:0006590 13 7 0,000 8,438E-03 0,03095352 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 8,438E-03 0,03090712 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 8,438E-03 0,03086085 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 8,438E-03 0,03081472 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 8,438E-03 0,03076873 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 8,438E-03 0,03072287 ! galactose metabolic process GO:0006012 13 7 0,000 8,438E-03 0,03067715 ! vesicle fusion GO:0006906 20 7 0,000 8,438E-03 0,03063157 ! response to dietary excess GO:0002021 8 7 0,000 8,438E-03 0,03058612 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 8,438E-03 0,03054081 ! intracellular pH reduction GO:0051452 13 7 0,000 8,438E-03 0,03049563 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 8,438E-03 0,03045059 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 8,438E-03 0,03040567 ! organ growth GO:0035265 15 7 0,000 8,438E-03 0,03036089 ! nucleoside transport GO:0015858 11 7 0,000 8,438E-03 0,03031624 ! nucleoside salvage GO:0043174 11 7 0,000 8,438E-03 0,03027173 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 8,438E-03 0,03022734 ! male sex determination GO:0030238 15 7 0,000 8,438E-03 0,03018308 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 8,438E-03 0,03013896 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 8,438E-03 0,03009496 ! parturition GO:0007567 16 7 0,000 8,438E-03 0,03005109 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 8,438E-03 0,03000735 ! rRNA modification GO:0000154 14 7 0,000 8,438E-03 0,02996373 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 8,438E-03 0,02992024 ! spindle checkpoint GO:0031577 16 7 0,000 8,438E-03 0,02987688 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 8,438E-03 0,02983364 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 8,438E-03 0,02979053 ! monocyte differentiation GO:0030224 16 7 0,000 8,438E-03 0,02974754 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 8,438E-03 0,02970468 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 8,438E-03 0,02966194 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 8,438E-03 0,02961932 ! hyaluronan metabolic process GO:0030212 9 7 0,000 8,438E-03 0,02957682 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 8,438E-03 0,02953445 ! anterograde axon cargo transport GO:0008089 18 7 0,000 8,438E-03 0,0294922 ! fibrinolysis GO:0042730 11 7 0,000 8,438E-03 0,02945007 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 8,438E-03 0,02940805 ! skeletal muscle contraction GO:0003009 8 7 0,000 8,438E-03 0,02936616 ! eating behavior GO:0042755 8 7 0,000 8,438E-03 0,02932439 ! B cell lineage commitment GO:0002326 21 7 0,000 8,438E-03 0,02928274 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 8,438E-03 0,0292412 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 8,438E-03 0,02919978 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 8,438E-03 0,02915848 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 8,438E-03 0,0291173 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 8,438E-03 0,02907623 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 8,438E-03 0,02903528 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 8,438E-03 0,02899444 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 8,438E-03 0,02895372 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 8,438E-03 0,02891311 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 8,438E-03 0,02887261 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 8,438E-03 0,02883223 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 8,438E-03 0,02879196 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 8,438E-03 0,02875181 ! histone ubiquitination GO:0016574 9 7 0,000 8,438E-03 0,02871176 ! regulation of meiosis GO:0040020 12 7 0,000 8,438E-03 0,02867183 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 8,438E-03 0,02863201 ! T cell lineage commitment GO:0002360 16 7 0,000 8,438E-03 0,0285923 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 8,438E-03 0,0285527 GO:0002714|positive regulation of B cell mediated immunity, ! membrane to membrane docking GO:0022614 14 7 0,000 8,438E-03 0,0285132 ! transcription termination GO:0006353 14 7 0,000 8,438E-03 0,02847382 ! coenzyme A metabolic process GO:0015936 12 7 0,000 8,438E-03 0,02843455 ! anaphase GO:0051322 18 7 0,000 8,438E-03 0,02839538 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 8,438E-03 0,02835632 ! axonal fasciculation GO:0007413 19 7 0,000 8,438E-03 0,02831737 ! negative regulation of nuclear division GO:0051784 15 7 0,000 8,438E-03 0,02827853 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 8,438E-03 0,02823979 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 8,438E-03 0,02820116 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 8,438E-03 0,02816263 ! diuresis GO:0030146 12 7 0,000 8,438E-03 0,02812421 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 8,438E-03 0,02808589 ! thiamin metabolic process GO:0006772 7 7 0,000 8,438E-03 0,02804768 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 8,438E-03 0,02800957 ! antibiotic transport GO:0042891 9 7 0,000 8,438E-03 0,02797157 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 8,438E-03 0,02793367 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 8,438E-03 0,02789587 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 8,438E-03 0,02785817 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 8,438E-03 0,02782058 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 8,438E-03 0,02778308 ! melanin biosynthetic process GO:0042438 10 7 0,000 8,438E-03 0,02774569 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 8,438E-03 0,0277084 ! dopamine biosynthetic process GO:0042416 18 7 0,000 8,438E-03 0,0276712 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 8,438E-03 0,02763411 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 8,438E-03 0,02759712 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 8,438E-03 0,02756022 ! endosome to lysosome transport GO:0008333 12 7 0,000 8,438E-03 0,02752343 ! protein modification by small protein removal GO:0070646 19 7 0,000 8,438E-03 0,02748673 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 8,438E-03 0,02745013 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 8,438E-03 0,02741363 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 8,438E-03 0,02737722 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 8,438E-03 0,02734091 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,438E-03 0,0273047 ! muscle adaptation GO:0043500 13 7 0,000 8,438E-03 0,02726858 ! embryonic heart tube development GO:0035050 14 7 0,000 8,438E-03 0,02723256 ! retina homeostasis GO:0001895 12 7 0,000 8,438E-03 0,02719663 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 8,438E-03 0,0271608 ! protein amino acid prenylation GO:0018346 19 7 0,000 8,438E-03 0,02712506 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 8,438E-03 0,02708942 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 8,438E-03 0,02705387 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 9,638E-03 0,03085996 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 9,638E-03 0,03081957 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 9,638E-03 0,03077928 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 9,638E-03 0,0307391 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 9,638E-03 0,03069902 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 9,638E-03 0,03065905 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 9,638E-03 0,03061918 ! male meiosis GO:0007140 9 8 0,000 9,638E-03 0,03057941 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 9,638E-03 0,03053975 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 9,638E-03 0,03050019 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 9,638E-03 0,03046073 ! meiotic prophase I GO:0007128 14 8 0,000 9,638E-03 0,03042138 ! response to zinc ion GO:0010043 12 8 0,000 9,638E-03 0,03038213 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 9,638E-03 0,03034297 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 9,638E-03 0,03030392 ! oligopeptide transport GO:0006857 16 8 0,000 9,638E-03 0,03026497 ! actin-myosin filament sliding GO:0033275 13 8 0,000 9,638E-03 0,03022612 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 9,638E-03 0,03018737 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 9,638E-03 0,03014872 ! signal peptide processing GO:0006465 12 8 0,000 9,638E-03 0,03011016 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 9,638E-03 0,03007171 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 9,638E-03 0,03003335 ! macrophage chemotaxis GO:0048246 12 8 0,000 9,638E-03 0,02999509 ! succinate metabolic process GO:0006105 17 8 0,000 9,638E-03 0,02995693 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 9,638E-03 0,02991887 ! membrane hyperpolarization GO:0060081 11 8 0,000 9,638E-03 0,0298809 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 9,638E-03 0,02984303 ! estrogen metabolic process GO:0008210 17 8 0,000 9,638E-03 0,02980525 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 9,638E-03 0,02976757 ! T-helper 1 type immune response GO:0042088 12 8 0,000 9,638E-03 0,02972998 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 9,638E-03 0,02969249 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 9,638E-03 0,0296551 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 9,638E-03 0,0296178 ! reflex GO:0060004 17 8 0,000 9,638E-03 0,02958059 ! endothelial cell differentiation GO:0045446 17 8 0,000 9,638E-03 0,02954347 ! glycerolipid catabolic process GO:0046503 14 8 0,000 9,638E-03 0,02950645 ! hemoglobin metabolic process GO:0020027 14 8 0,000 9,638E-03 0,02946952 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 9,638E-03 0,02943269 ! pigment granule organization GO:0048753 17 8 0,000 9,638E-03 0,02939594 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 9,638E-03 0,02935929 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 9,638E-03 0,02932272 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 9,638E-03 0,02928625 ! astrocyte differentiation GO:0048708 19 8 0,000 9,638E-03 0,02924987 ! histidine catabolic process GO:0006548 10 8 0,000 9,638E-03 0,02921358 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 9,638E-03 0,02917738 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 9,638E-03 0,02914127 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 9,638E-03 0,02910525 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 9,638E-03 0,02906932 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 9,638E-03 0,02903347 ! regulation of pigmentation during development GO:0048070 25 8 0,000 9,638E-03 0,02899772 ! melanin metabolic process GO:0006582 17 8 0,000 9,638E-03 0,02896205 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 9,638E-03 0,02892647 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 9,638E-03 0,02889098 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 9,638E-03 0,02885557 ! macrophage activation GO:0042116 13 8 0,000 9,638E-03 0,02882025 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 9,638E-03 0,02878502 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 9,638E-03 0,02874988 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 9,638E-03 0,02871481 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 9,638E-03 0,02867984 ! purine salvage GO:0043101 12 8 0,000 9,638E-03 0,02864495 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 9,638E-03 0,02861014 ! regulation of vascular permeability GO:0043114 12 8 0,000 9,638E-03 0,02857542 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 9,638E-03 0,02854079 ! osteoblast development GO:0002076 17 8 0,000 9,638E-03 0,02850623 ! positive regulation of vasodilation GO:0045909 14 8 0,000 9,638E-03 0,02847176 ! negative regulation of translational initiation GO:0045947 12 8 0,000 9,638E-03 0,02843738 ! Schwann cell differentiation GO:0014037 21 8 0,000 9,638E-03 0,02840307 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 9,638E-03 0,02836885 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 9,638E-03 0,02833471 ! response to UV-B GO:0010224 17 8 0,000 9,638E-03 0,02830066 ! protein targeting to vacuole GO:0006623 14 8 0,000 9,638E-03 0,02826668 ! protein retention in ER lumen GO:0006621 14 8 0,000 9,638E-03 0,02823279 ! intermediate filament organization GO:0045109 12 8 0,000 9,638E-03 0,02819898 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 9,638E-03 0,02816525 ! cellular extravasation GO:0045123 13 8 0,000 9,638E-03 0,0281316 ! cardiac muscle cell development GO:0055013 14 8 0,000 9,638E-03 0,02809803 ! response to antibiotic GO:0046677 11 8 0,000 9,638E-03 0,02806454 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 9,638E-03 0,02803113 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 9,638E-03 0,0279978 ! DNA topological change GO:0006265 12 8 0,000 9,638E-03 0,02796455 ! response to tropane GO:0014073 15 8 0,000 9,638E-03 0,02793137 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 9,638E-03 0,02789828 ! melanosome transport GO:0032402 13 8 0,000 9,638E-03 0,02786526 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 9,638E-03 0,02783233 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 9,638E-03 0,02779947 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 9,638E-03 0,02776668 ! mast cell activation GO:0045576 14 8 0,000 9,638E-03 0,02773398 ! multicellular organismal aging GO:0010259 20 8 0,000 9,638E-03 0,02770135 ! gas homeostasis GO:0033483 14 8 0,000 9,638E-03 0,0276688 ! dendrite morphogenesis GO:0048813 14 8 0,000 9,638E-03 0,02763632 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 9,638E-03 0,02760392 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 9,638E-03 0,0275716 ! nucleosome disassembly GO:0006337 14 8 0,000 9,638E-03 0,02753935 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 9,638E-03 0,02750718 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 9,638E-03 0,02747509 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 9,638E-03 0,02744306 ! establishment of chromosome localization GO:0051303 14 8 0,000 9,638E-03 0,02741112 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 9,638E-03 0,02737924 ! intracellular lipid transport GO:0032365 16 8 0,000 9,638E-03 0,02734744 ! response to tumor cell GO:0002347 16 8 0,000 9,638E-03 0,02731572 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 9,638E-03 0,02728406 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 9,638E-03 0,02725249 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 9,638E-03 0,02722098 ! positive regulation of epidermis development GO:0045684 13 8 0,000 9,638E-03 0,02718955 ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 9,638E-03 0,02715819 ! hormone catabolic process GO:0042447 17 8 0,000 9,638E-03 0,0271269 ! glycolipid catabolic process GO:0019377 16 8 0,000 9,638E-03 0,02709568 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 9,638E-03 0,02706454 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 9,638E-03 0,02703346 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 9,638E-03 0,02700246 ! positive regulation of glucose import GO:0046326 8 8 0,000 9,638E-03 0,02697153 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 9,638E-03 0,02694067 ! adult feeding behavior GO:0008343 10 8 0,000 9,638E-03 0,02690988 ! ATP catabolic process GO:0006200 11 8 0,000 9,638E-03 0,02687916 ! blastocyst growth GO:0001832 19 8 0,000 9,638E-03 0,02684852 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 9,638E-03 0,02681794 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 9,638E-03 0,02678743 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 9,638E-03 0,02675699 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 9,638E-03 0,02672662 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 9,638E-03 0,02669631 ! amino sugar catabolic process GO:0046348 11 8 0,000 9,638E-03 0,02666608 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 9,638E-03 0,02663591 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 9,638E-03 0,02660582 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 9,638E-03 0,02657579 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 9,638E-03 0,02654583 ! behavioral response to nicotine GO:0035095 12 8 0,000 9,638E-03 0,02651593 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 9,638E-03 0,02648611 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 9,638E-03 0,02645635 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 9,638E-03 0,02642665 ! NAD biosynthetic process GO:0009435 17 8 0,000 9,638E-03 0,02639703 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 9,638E-03 0,02636747 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 9,638E-03 0,02633797 ! axon extension GO:0048675 16 9 0,000 0,01083659 0,02957965 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01083659 0,02954664 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01083659 0,0295137 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01083659 0,02948083 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01083659 0,02944804 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01083659 0,02941532 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01083659 0,02938267 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01083659 0,02935009 ! reproductive behavior GO:0019098 22 9 0,000 0,01083659 0,02931759 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01083659 0,02928516 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01083659 0,0292528 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01083659 0,02922051 ! UTP metabolic process GO:0046051 10 9 0,000 0,01083659 0,0291883 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01083659 0,02915615 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01083659 0,02912408 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01083659 0,02909207 ! artery development GO:0060840 25 9 0,000 0,01083659 0,02906014 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01083659 0,02902827 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01083659 0,02899648 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01083659 0,02896475 ! equilibrioception GO:0050957 20 9 0,000 0,01083659 0,0289331 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01083659 0,02890151 ! chemosensory behavior GO:0007635 21 9 0,000 0,01083659 0,02886999 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01083659 0,02883855 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01083659 0,02880717 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01083659 0,02877585 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01083659 0,02874461 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01083659 0,02871343 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01083659 0,02868232 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01083659 0,02865128 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01083659 0,02862031 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01083659 0,0285894 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01083659 0,02855856 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01083659 0,02852779 ! protein targeting to ER GO:0045047 25 9 0,000 0,01083659 0,02849708 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01083659 0,02846644 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01083659 0,02843586 ! T cell selection GO:0045058 27 9 0,000 0,01083659 0,02840535 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01083659 0,0283749 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01083659 0,02834452 ! glycine catabolic process GO:0006546 15 9 0,000 0,01083659 0,02831421 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01083659 0,02828396 ! endosome organization GO:0007032 20 9 0,000 0,01083659 0,02825377 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01083659 0,02822365 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01083659 0,02819359 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01083659 0,0281636 ! mannose metabolic process GO:0006013 13 9 0,000 0,01083659 0,02813367 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01083659 0,02810381 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01083659 0,028074 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01083659 0,02804426 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01083659 0,02801459 ! receptor clustering GO:0043113 20 9 0,000 0,01083659 0,02798497 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01083659 0,02795542 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01083659 0,02792593 ! retinol metabolic process GO:0042572 20 9 0,000 0,01083659 0,02789651 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01083659 0,02786714 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01083659 0,02783784 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01083659 0,0278086 ! macrophage differentiation GO:0030225 15 9 0,000 0,01083659 0,02777942 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01083659 0,0277503 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01083659 0,02772124 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01083659 0,02769224 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01083659 0,02766331 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01083659 0,02763443 ! response to amine stimulus GO:0014075 13 9 0,000 0,01083659 0,02760562 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01083659 0,02757686 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01083659 0,02754816 ! erythrocyte development GO:0048821 17 9 0,000 0,01083659 0,02751953 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01083659 0,02749095 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01083659 0,02746243 ! renal water homeostasis GO:0003091 15 9 0,000 0,01083659 0,02743397 ! postreplication repair GO:0006301 25 9 0,000 0,01083659 0,02740557 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01083659 0,02737723 ! icosanoid secretion GO:0032309 15 9 0,000 0,01083659 0,02734895 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01083659 0,02732073 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01083659 0,02729256 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01083659 0,02726445 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01083659 0,0272364 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01083659 0,02720841 ! sterol catabolic process GO:0016127 14 9 0,000 0,01083659 0,02718048 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01083659 0,0271526 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01083659 0,02712478 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01083659 0,02709702 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01083659 0,02706931 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01083659 0,02704166 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01083659 0,02701407 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01083659 0,02698653 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01083659 0,02695905 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01083659 0,02693162 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01083659 0,02690425 ! purine base metabolic process GO:0006144 25 9 0,000 0,01083659 0,02687694 ! pigment granule transport GO:0051904 17 9 0,000 0,01083659 0,02684968 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01083659 0,02682248 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01083659 0,02679533 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01083659 0,02676824 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01083659 0,0267412 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01083659 0,02671421 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01083659 0,02668728 ! mitochondrion localization GO:0051646 18 9 0,000 0,01083659 0,02666041 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01203355 0,02957541 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01203355 0,02954569 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01203355 0,02951603 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01203355 0,02948642 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01203355 0,02945688 ! associative learning GO:0008306 21 10 0,000 0,01203355 0,02942739 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01203355 0,02939796 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01203355 0,02936859 ! phosphate transport GO:0006817 24 10 0,000 0,01203355 0,02933928 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01203355 0,02931003 ! CTP metabolic process GO:0046036 11 10 0,000 0,01203355 0,02928084 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01203355 0,0292517 ! GTP metabolic process GO:0046039 11 10 0,000 0,01203355 0,02922263 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01203355 0,02919361 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01203355 0,02916464 ! social behavior GO:0035176 29 10 0,000 0,01203355 0,02913574 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01203355 0,02910689 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01203355 0,0290781 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01203355 0,02904937 ! androgen metabolic process GO:0008209 17 10 0,000 0,01203355 0,02902069 ! phospholipid efflux GO:0033700 19 10 0,000 0,01203355 0,02899207 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01203355 0,02896351 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01203355 0,028935 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01203355 0,02890655 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01203355 0,02887816 ! lung alveolus development GO:0048286 26 10 0,000 0,01203355 0,02884982 ! pathogenesis GO:0009405 17 10 0,000 0,01203355 0,02882153 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01203355 0,0287933 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01203355 0,02876513 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01203355 0,02873701 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01203355 0,02870895 ! endoderm development GO:0007492 18 10 0,000 0,01203355 0,02868094 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01203355 0,02865298 ! arginine catabolic process GO:0006527 17 10 0,000 0,01203355 0,02862508 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01203355 0,02859724 ! proline metabolic process GO:0006560 13 10 0,000 0,01203355 0,02856945 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01203355 0,02854171 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01203355 0,02851403 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01203355 0,0284864 ! V(D)J recombination GO:0033151 34 10 0,000 0,01203355 0,02845882 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01203355 0,0284313 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01203355 0,02840383 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01203355 0,02837641 ! B cell proliferation GO:0042100 19 10 0,000 0,01203355 0,02834905 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01203355 0,02832174 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01203355 0,02829448 ! multicellular organism growth GO:0035264 19 10 0,000 0,01203355 0,02826727 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01203355 0,02824012 ! ruffle organization GO:0031529 17 10 0,000 0,01203355 0,02821302 ! epithelial cell development GO:0002064 21 10 0,000 0,01203355 0,02818597 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01203355 0,02815897 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01203355 0,02813202 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01203355 0,02810513 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01203355 0,02807828 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01203355 0,02805149 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01203355 0,02802475 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01203355 0,02799806 ! motor axon guidance GO:0008045 22 10 0,000 0,01203355 0,02797142 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01203355 0,02794483 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01203355 0,02791829 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01203355 0,0278918 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01203355 0,02786537 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01203355 0,02783898 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01203355 0,02781264 ! segment specification GO:0007379 15 10 0,000 0,01203355 0,02778635 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01203355 0,02776012 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01203355 0,02773393 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01203355 0,02770779 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01203355 0,0276817 ! response to dsRNA GO:0043331 23 10 0,000 0,01203355 0,02765566 ! DNA ligation GO:0006266 18 10 0,000 0,01203355 0,02762966 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01203355 0,02760372 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01203355 0,02757783 ! melanosome localization GO:0032400 16 10 0,000 0,01203355 0,02755198 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01203355 0,02752618 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01203355 0,02750043 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01203355 0,02747473 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01203355 0,02744908 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01203355 0,02742347 ! induction of an organ GO:0001759 17 10 0,000 0,01203355 0,02739791 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01203355 0,0273724 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01203355 0,02734694 ! protein sumoylation GO:0016925 17 10 0,000 0,01203355 0,02732153 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01203355 0,02729616 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01203355 0,02727084 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01203355 0,02724556 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01203355 0,02722034 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01203355 0,02719515 ! salivary gland development GO:0007431 28 10 0,000 0,01203355 0,02717002 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01203355 0,02714493 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01203355 0,02711989 ! midbrain development GO:0030901 14 10 0,000 0,01203355 0,0270949 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01203355 0,02706995 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01203355 0,02704504 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01203355 0,02702019 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01203355 0,02699537 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01203355 0,02697061 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01203355 0,02694589 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01203355 0,02692121 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01203355 0,02689658 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01203355 0,02687199 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01203355 0,02684745 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01203355 0,02682296 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01203355 0,02679851 ! blastocyst formation GO:0001825 18 10 0,000 0,01203355 0,0267741 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01203355 0,02674974 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01203355 0,02672542 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01203355 0,02670115 ! response to nicotine GO:0035094 20 10 0,000 0,01203355 0,02667692 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01203355 0,02665273 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01203355 0,02662859 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,0132291 0,02924768 ! respiratory burst GO:0045730 17 11 0,000 0,0132291 0,02922123 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0132291 0,02919484 ! neuron fate specification GO:0048665 18 11 0,000 0,0132291 0,02916849 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0132291 0,02914218 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0132291 0,02911593 ! thyroid gland development GO:0030878 26 11 0,000 0,0132291 0,02908972 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,0132291 0,02906356 ! synapsis GO:0007129 14 11 0,000 0,0132291 0,02903745 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0132291 0,02901138 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,0132291 0,02898537 ! response to pain GO:0048265 27 11 0,000 0,0132291 0,02895939 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0132291 0,02893347 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,0132291 0,02890759 ! blood vessel remodeling GO:0001974 30 11 0,000 0,0132291 0,02888175 ! bone resorption GO:0045453 16 11 0,000 0,0132291 0,02885597 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0132291 0,02883023 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,0132291 0,02880453 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0132291 0,02877888 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0132291 0,02875328 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0132291 0,02872772 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0132291 0,0287022 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0132291 0,02867674 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,0132291 0,02865131 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,0132291 0,02862594 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,0132291 0,0286006 ! UV protection GO:0009650 20 11 0,000 0,0132291 0,02857532 ! adult heart development GO:0007512 16 11 0,000 0,0132291 0,02855007 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,0132291 0,02852487 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0132291 0,02849972 ! macroautophagy GO:0016236 19 11 0,000 0,0132291 0,02847461 ! temperature homeostasis GO:0001659 18 11 0,000 0,0132291 0,02844954 ! behavioral fear response GO:0001662 27 11 0,000 0,0132291 0,02842452 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0132291 0,02839955 ! negative regulation of ossification GO:0030279 27 11 0,000 0,0132291 0,02837461 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,0132291 0,02834972 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0132291 0,02832488 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,0132291 0,02830007 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,0132291 0,02827531 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0132291 0,0282506 ! regulation of organ growth GO:0046620 14 11 0,000 0,0132291 0,02822592 ! pigment granule localization GO:0051875 20 11 0,000 0,0132291 0,02820129 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0132291 0,02817671 ! vasoconstriction GO:0042310 20 11 0,000 0,0132291 0,02815216 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0132291 0,02812766 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0132291 0,0281032 ! embryonic axis specification GO:0000578 19 11 0,000 0,0132291 0,02807879 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0132291 0,02805441 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0132291 0,02803008 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0132291 0,02800579 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,0132291 0,02798154 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0132291 0,02795734 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0132291 0,02793317 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0132291 0,02790905 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0132291 0,02788497 ! prophase GO:0051324 17 11 0,000 0,0132291 0,02786093 ! neuroblast proliferation GO:0007405 25 11 0,000 0,0132291 0,02783694 ! nucleosome positioning GO:0016584 15 11 0,000 0,0132291 0,02781298 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0132291 0,02778907 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0132291 0,02776519 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0132291 0,02774136 ! apical protein localization GO:0045176 18 11 0,000 0,0132291 0,02771757 ! acid secretion GO:0046717 20 11 0,000 0,0132291 0,02769382 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0132291 0,02767011 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0132291 0,02764644 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0132291 0,02762281 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0132291 0,02759922 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,0132291 0,02757567 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,0132291 0,02755216 ! cholesterol efflux GO:0033344 21 11 0,000 0,0132291 0,02752869 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0132291 0,02750526 ! oocyte development GO:0048599 20 11 0,000 0,0132291 0,02748187 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,0132291 0,02745852 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,0132291 0,02743521 ! embryonic gut development GO:0048566 19 11 0,000 0,0132291 0,02741194 ! activation of innate immune response GO:0002218 16 11 0,000 0,0132291 0,02738871 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0132291 0,02736552 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,0132291 0,02734237 ! lysogeny GO:0030069 22 11 0,000 0,0132291 0,02731926 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0132291 0,02729618 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,0132291 0,02727315 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0132291 0,02725015 ! regulation of embryonic development GO:0045995 35 11 0,000 0,0132291 0,0272272 ! nucleus localization GO:0051647 22 11 0,000 0,0132291 0,02720428 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01442323 0,02963495 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01442323 0,02961004 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01442323 0,02958518 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01442323 0,02956036 ! virus-host interaction GO:0019048 30 12 0,000 0,01442323 0,02953558 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,01442323 0,02951085 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01442323 0,02948615 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01442323 0,0294615 ! protein complex disassembly GO:0043241 28 12 0,000 0,01442323 0,02943688 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01442323 0,02941231 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01442323 0,02938778 ! hippocampus development GO:0021766 29 12 0,000 0,01442323 0,02936329 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01442323 0,02933884 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01442323 0,02931444 ! T cell proliferation GO:0042098 32 12 0,000 0,01442323 0,02929007 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01442323 0,02926574 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01442323 0,02924145 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01442323 0,02921721 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01442323 0,029193 ! drug transport GO:0015893 16 12 0,000 0,01442323 0,02916883 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01442323 0,02914471 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01442323 0,02912062 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01442323 0,02909657 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01442323 0,02907257 ! focal adhesion formation GO:0048041 37 12 0,000 0,01442323 0,0290486 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01442323 0,02902467 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01442323 0,02900078 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01442323 0,02897693 ! lipid digestion GO:0044241 21 12 0,000 0,01442323 0,02895312 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01442323 0,02892935 ! entry into host cell GO:0030260 34 12 0,000 0,01442323 0,02890562 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01442323 0,02888193 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01442323 0,02885827 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01442323 0,02883466 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01442323 0,02881108 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01442323 0,02878754 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01442323 0,02876404 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01442323 0,02874058 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01442323 0,02871716 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01442323 0,02869377 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01442323 0,02867042 ! cranial nerve development GO:0021545 23 12 0,000 0,01442323 0,02864711 ! fucose catabolic process GO:0019317 25 12 0,000 0,01442323 0,02862384 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01442323 0,02860061 ! histone acetylation GO:0016573 27 12 0,000 0,01442323 0,02857741 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01442323 0,02855426 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01442323 0,02853113 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01442323 0,02850805 ! zymogen activation GO:0031638 18 12 0,000 0,01442323 0,028485 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01442323 0,028462 ! T cell homeostasis GO:0043029 28 12 0,000 0,01442323 0,02843902 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01442323 0,02841609 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01442323 0,02839319 ! oocyte differentiation GO:0009994 21 12 0,000 0,01442323 0,02837033 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01442323 0,02834751 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01442323 0,02832472 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01442323 0,02830197 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01442323 0,02827925 ! defense response to fungus GO:0050832 15 12 0,000 0,01442323 0,02825658 ! developmental induction GO:0031128 22 12 0,000 0,01442323 0,02823394 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01442323 0,02821133 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01442323 0,02818876 ! response to cold GO:0009409 17 12 0,000 0,01442323 0,02816623 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01442323 0,02814373 ! localization within membrane GO:0051668 26 12 0,000 0,01442323 0,02812127 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01561595 0,03042247 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01561595 0,03039822 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01561595 0,03037402 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01561595 0,03034986 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01561595 0,03032573 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01561595 0,03030165 ! peroxisomal transport GO:0043574 28 13 0,000 0,01561595 0,0302776 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01561595 0,03025359 ! cartilage condensation GO:0001502 22 13 0,000 0,01561595 0,03022961 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01561595 0,03020568 ! organelle fusion GO:0048284 36 13 0,000 0,01561595 0,03018178 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01561595 0,03015792 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01561595 0,0301341 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01561595 0,03011032 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01561595 0,03008657 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01561595 0,03006286 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01561595 0,03003919 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01561595 0,03001556 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01561595 0,02999196 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01561595 0,0299684 ! methionine metabolic process GO:0006555 31 13 0,000 0,01561595 0,02994488 ! plasma membrane organization GO:0007009 27 13 0,000 0,01561595 0,02992139 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01561595 0,02989794 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01561595 0,02987453 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01561595 0,02985115 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01561595 0,02982781 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01561595 0,02980451 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01561595 0,02978124 ! exocrine system development GO:0035272 34 13 0,000 0,01561595 0,02975801 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01561595 0,02973482 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01561595 0,02971166 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01561595 0,02968854 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01561595 0,02966545 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01561595 0,0296424 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01561595 0,02961939 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01561595 0,02959641 ! protein homotetramerization GO:0051289 24 13 0,000 0,01561595 0,02957347 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01561595 0,02955056 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01561595 0,02952769 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01561595 0,02950485 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01561595 0,02948205 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01561595 0,02945928 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01561595 0,02943655 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01561595 0,02941386 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01561595 0,0293912 ! histone methylation GO:0016571 29 13 0,000 0,01561595 0,02936857 ! chromatin silencing GO:0006342 29 13 0,000 0,01561595 0,02934598 ! gland morphogenesis GO:0022612 31 13 0,000 0,01561595 0,02932342 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01561595 0,0293009 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01561595 0,02927841 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01561595 0,02925596 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01561595 0,02923354 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01561595 0,02921116 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01561595 0,02918881 ! spleen development GO:0048536 24 13 0,000 0,01561595 0,02916649 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01561595 0,02914421 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01561595 0,02912196 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01561595 0,02909975 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01561595 0,02907757 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01561595 0,02905542 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01561595 0,02903331 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01561595 0,02901123 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01561595 0,02898919 ! insulin secretion GO:0030073 24 13 0,000 0,01561595 0,02896718 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01561595 0,0289452 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01561595 0,02892325 ! acrosome reaction GO:0007340 19 13 0,000 0,01561595 0,02890134 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01561595 0,02887946 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01561595 0,02885762 ! rRNA transcription GO:0009303 28 14 0,000 0,01680726 0,03103564 ! regulation of S phase GO:0033261 26 14 0,000 0,01680726 0,0310122 ! water transport GO:0006833 21 14 0,000 0,01680726 0,03098879 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01680726 0,03096542 ! non-recombinational repair GO:0000726 29 14 0,000 0,01680726 0,03094209 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01680726 0,03091879 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01680726 0,03089552 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01680726 0,03087229 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01680726 0,0308491 ! lipid localization GO:0010876 32 14 0,000 0,01680726 0,03082594 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01680726 0,03080281 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01680726 0,03077972 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01680726 0,03075666 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01680726 0,03073364 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01680726 0,03071066 ! arginine metabolic process GO:0006525 21 14 0,000 0,01680726 0,0306877 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01680726 0,03066478 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01680726 0,0306419 ! regulation of heart rate GO:0002027 25 14 0,000 0,01680726 0,03061905 ! fear response GO:0042596 34 14 0,000 0,01680726 0,03059623 ! organic alcohol transport GO:0015850 29 14 0,000 0,01680726 0,03057345 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01680726 0,0305507 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01680726 0,03052799 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01680726 0,03050531 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01680726 0,03048266 ! bone mineralization GO:0030282 18 14 0,000 0,01680726 0,03046005 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01680726 0,03043747 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01680726 0,03041492 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01680726 0,03039241 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01680726 0,03036993 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01680726 0,03034748 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01680726 0,03032507 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01680726 0,03030269 ! ribosome assembly GO:0042255 18 14 0,000 0,01680726 0,03028034 ! cerebellum development GO:0021549 23 14 0,000 0,01680726 0,03025803 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01680726 0,03023575 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01680726 0,0302135 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01680726 0,03019128 ! response to gamma radiation GO:0010332 30 14 0,000 0,01680726 0,0301691 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01680726 0,03014695 ! NADP metabolic process GO:0006739 24 14 0,000 0,01680726 0,03012483 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01680726 0,03010275 ! oxygen transport GO:0015671 22 14 0,000 0,01680726 0,03008069 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01680726 0,03005867 ! male genitalia development GO:0030539 26 14 0,000 0,01680726 0,03003668 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01680726 0,03001473 ! regulation of axon extension GO:0030516 43 14 0,000 0,01680726 0,0299928 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01680726 0,02997091 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01680726 0,02994905 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01680726 0,02992722 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01799717 0,03202264 ! lactation GO:0007595 30 15 0,000 0,01799717 0,03199933 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01799717 0,03197606 ! reproductive cellular process GO:0048610 22 15 0,000 0,01799717 0,03195282 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01799717 0,03192962 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01799717 0,03190645 ! superoxide anion generation GO:0042554 22 15 0,000 0,01799717 0,03188331 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01799717 0,0318602 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01799717 0,03183713 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01799717 0,0318141 ! copper ion transport GO:0006825 22 15 0,000 0,01799717 0,03179109 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01799717 0,03176812 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01799717 0,03174519 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01799717 0,03172228 ! sulfate transport GO:0008272 27 15 0,000 0,01799717 0,03169941 ! response to cAMP GO:0051591 25 15 0,000 0,01799717 0,03167657 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01799717 0,03165377 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01799717 0,03163099 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01799717 0,03160825 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01799717 0,03158555 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01799717 0,03156287 ! vesicle coating GO:0006901 38 15 0,000 0,01799717 0,03154023 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01799717 0,03151762 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01799717 0,03149504 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01799717 0,0314725 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01799717 0,03144999 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01799717 0,03142751 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01799717 0,03140506 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01799717 0,03138264 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01799717 0,03136026 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01799717 0,03133791 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01799717 0,03131559 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01799717 0,0312933 ! histone deacetylation GO:0016575 24 15 0,000 0,01799717 0,03127104 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01799717 0,03124881 ! water homeostasis GO:0030104 28 15 0,000 0,01799717 0,03122662 ! cofactor transport GO:0051181 30 15 0,000 0,01799717 0,03120446 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01799717 0,03118233 ! muscle maintenance GO:0046716 26 15 0,000 0,01799717 0,03116023 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01799717 0,03113816 ! intestinal absorption GO:0050892 31 15 0,000 0,01799717 0,03111612 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01799717 0,03109412 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01799717 0,03107214 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01799717 0,0310502 ! cell killing GO:0001906 32 15 0,000 0,01799717 0,03102829 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01799717 0,03100641 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01799717 0,03098455 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01799717 0,03096273 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01799717 0,03094094 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01799717 0,03091919 ! actin filament polymerization GO:0030041 27 15 0,000 0,01799717 0,03089746 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01799717 0,03087576 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,01918567 0,03289164 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01918567 0,03286857 ! positive regulation of cell size GO:0045793 29 16 0,000 0,01918567 0,03284554 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01918567 0,03282254 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01918567 0,03279957 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01918567 0,03277663 ! bone remodeling GO:0046849 28 16 0,000 0,01918567 0,03275373 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01918567 0,03273085 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01918567 0,03270801 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01918567 0,0326852 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01918567 0,03266243 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01918567 0,03263968 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01918567 0,03261697 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01918567 0,03259428 ! startle response GO:0001964 28 16 0,000 0,01918567 0,03257163 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01918567 0,03254901 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01918567 0,03252643 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01918567 0,03250387 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01918567 0,03248135 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01918567 0,03245885 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01918567 0,03243639 ! pituitary gland development GO:0021983 30 16 0,000 0,01918567 0,03241396 ! response to osmotic stress GO:0006970 27 16 0,000 0,01918567 0,03239156 ! lysosomal transport GO:0007041 31 16 0,000 0,01918567 0,03236919 ! L-amino acid transport GO:0015807 33 16 0,000 0,01918567 0,03234685 ! stem cell development GO:0048864 46 16 0,000 0,01918567 0,03232454 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01918567 0,03230226 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01918567 0,03228001 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01918567 0,0322578 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01918567 0,03223561 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01918567 0,03221346 ! axon cargo transport GO:0008088 46 16 0,000 0,01918567 0,03219133 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01918567 0,03216924 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01918567 0,03214718 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01918567 0,03212514 ! DNA replication initiation GO:0006270 28 16 0,000 0,01918567 0,03210314 ! neuron recognition GO:0008038 40 16 0,000 0,01918567 0,03208116 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01918567 0,03205922 ! tissue regeneration GO:0042246 27 16 0,000 0,01918567 0,03203731 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01918567 0,03201542 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01918567 0,03199357 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01918567 0,03197175 ! biomineral formation GO:0031214 22 16 0,000 0,01918567 0,03194995 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01918567 0,03192819 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01918567 0,03190645 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01918567 0,03188475 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01918567 0,03186307 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01918567 0,03184143 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01918567 0,03181981 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01918567 0,03179822 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01918567 0,03177667 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01918567 0,03175514 ! peptide hormone processing GO:0016486 27 16 0,000 0,01918567 0,03173364 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02037276 0,03367432 ! metencephalon development GO:0022037 32 17 0,000 0,02037276 0,03365155 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02037276 0,03362882 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02037276 0,03360611 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02037276 0,03358343 ! signal complex assembly GO:0007172 47 17 0,000 0,02037276 0,03356079 ! filopodium assembly GO:0046847 42 17 0,000 0,02037276 0,03353817 ! endothelial cell migration GO:0043542 31 17 0,000 0,02037276 0,03351559 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02037276 0,03349303 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02037276 0,03347051 ! glial cell development GO:0021782 28 17 0,000 0,02037276 0,03344802 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02037276 0,03342555 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02037276 0,03340312 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02037276 0,03338072 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02037276 0,03335834 ! myoblast differentiation GO:0045445 50 17 0,000 0,02037276 0,033336 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02037276 0,03331369 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02037276 0,0332914 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02037276 0,03326915 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02037276 0,03324693 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02037276 0,03322473 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02037276 0,03320257 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02037276 0,03318043 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02037276 0,03315833 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02037276 0,03313625 ! regulation of protein binding GO:0043393 33 17 0,000 0,02037276 0,0331142 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02037276 0,03309219 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02037276 0,0330702 ! genitalia development GO:0048806 32 17 0,000 0,02037276 0,03304824 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02037276 0,03302631 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02037276 0,03300441 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02037276 0,03298254 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02037276 0,03296069 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02037276 0,03293888 ! steroid catabolic process GO:0006706 34 17 0,000 0,02037276 0,0329171 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02037276 0,03289534 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02037276 0,03287361 ! gas transport GO:0015669 26 17 0,000 0,02037276 0,03285191 ! organic cation transport GO:0015695 32 17 0,000 0,02037276 0,03283024 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02037276 0,0328086 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02037276 0,03278699 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02037276 0,0327654 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02155845 0,03464953 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02155845 0,03462675 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02155845 0,034604 ! limbic system development GO:0021761 40 18 0,000 0,02155845 0,03458128 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02155845 0,03455859 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02155845 0,03453593 ! adult walking behavior GO:0007628 36 18 0,000 0,02155845 0,03451329 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02155845 0,03449069 ! heart looping GO:0001947 34 18 0,000 0,02155845 0,03446812 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02155845 0,03444558 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02155845 0,03442306 ! centrosome cycle GO:0007098 26 18 0,000 0,02155845 0,03440058 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02155845 0,03437812 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02155845 0,0343557 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02155845 0,0343333 ! glycine metabolic process GO:0006544 30 18 0,000 0,02155845 0,03431094 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02155845 0,0342886 ! response to retinoic acid GO:0032526 31 18 0,000 0,02155845 0,03426629 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02155845 0,03424401 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,02155845 0,03422176 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02155845 0,03419954 ! DNA integration GO:0015074 32 18 0,000 0,02155845 0,03417734 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02155845 0,03415518 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02155845 0,03413304 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02155845 0,03411094 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02155845 0,03408886 ! neural crest cell migration GO:0001755 41 18 0,000 0,02155845 0,03406681 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02155845 0,03404479 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02155845 0,03402279 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02155845 0,03400083 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02155845 0,03397889 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02155845 0,03395699 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02155845 0,03393511 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02155845 0,03391326 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02155845 0,03389143 ! detection of bacterium GO:0016045 22 18 0,000 0,02155845 0,03386964 ! nerve development GO:0021675 34 18 0,000 0,02155845 0,03384787 ! defense response to virus GO:0051607 43 18 0,000 0,02155845 0,03382613 ! microspike assembly GO:0030035 46 18 0,000 0,02155845 0,03380442 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02155845 0,03378274 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02155845 0,03376108 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02274273 0,03559289 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02274273 0,0355701 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02274273 0,03554734 ! neuron maturation GO:0042551 46 19 0,000 0,02274273 0,03552462 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02274273 0,03550192 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02274273 0,03547925 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02274273 0,0354566 ! inositol metabolic process GO:0006020 33 19 0,000 0,02274273 0,03543399 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02274273 0,03541141 ! memory GO:0007613 34 19 0,000 0,02274273 0,03538885 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02274273 0,03536633 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02274273 0,03534383 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02274273 0,03532136 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02274273 0,03529892 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02274273 0,03527651 ! cerebral cortex development GO:0021987 40 19 0,000 0,02274273 0,03525412 ! pigmentation during development GO:0048066 42 19 0,000 0,02274273 0,03523177 ! response to vitamin A GO:0033189 32 19 0,000 0,02274273 0,03520944 ! heme metabolic process GO:0042168 40 19 0,000 0,02274273 0,03518714 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02274273 0,03516487 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02274273 0,03514263 ! response to fungus GO:0009620 26 19 0,000 0,02274273 0,03512042 ! protein export from nucleus GO:0006611 40 19 0,000 0,02274273 0,03509823 ! heart process GO:0003015 32 19 0,000 0,02274273 0,03507607 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02274273 0,03505394 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02274273 0,03503184 ! cellular pigmentation GO:0033059 37 19 0,000 0,02274273 0,03500977 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02274273 0,03498772 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02274273 0,0349657 ! vitamin transport GO:0051180 31 19 0,000 0,02274273 0,03494371 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02274273 0,03492175 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02274273 0,03489981 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02274273 0,0348779 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02274273 0,03485602 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02274273 0,03483417 ! cilium assembly GO:0042384 38 19 0,000 0,02274273 0,03481234 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02274273 0,03479054 ! protein secretion GO:0009306 45 20 0,000 0,02392562 0,03657715 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02392562 0,03655428 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02392562 0,03653143 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02392562 0,03650862 ! skin development GO:0043588 42 20 0,000 0,02392562 0,03648583 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,02392562 0,03646306 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02392562 0,03644033 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02392562 0,03641763 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02392562 0,03639495 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,02392562 0,0363723 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02392562 0,03634968 ! response to vitamin GO:0033273 36 20 0,000 0,02392562 0,03632709 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02392562 0,03630453 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,02392562 0,03628199 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02392562 0,03625949 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02392562 0,03623701 ! response to alkaloid GO:0043279 38 20 0,000 0,02392562 0,03621456 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02392562 0,03619213 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02392562 0,03616974 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,02392562 0,03614737 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02392562 0,03612503 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,02392562 0,03610271 ! actin filament bundle formation GO:0051017 47 20 0,000 0,02392562 0,03608043 ! body fluid secretion GO:0007589 33 20 0,000 0,02392562 0,03605817 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02392562 0,03603594 ! peptide secretion GO:0002790 38 20 0,000 0,02392562 0,03601374 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02392562 0,03599156 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,02392562 0,03596941 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02392562 0,03594729 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02392562 0,0359252 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02392562 0,03590313 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02392562 0,03588109 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02392562 0,03585908 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02392562 0,03583709 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02392562 0,03581513 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02392562 0,0357932 ! regulation of glucose import GO:0046324 30 20 0,000 0,02392562 0,03577129 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02392562 0,03574941 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02392562 0,03572756 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02392562 0,03570574 ! negative regulation of translation GO:0017148 32 20 0,000 0,02392562 0,03568394 ! regulation of cell killing GO:0031341 46 21 0,000 0,02510711 0,03742323 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02510711 0,03740041 ! hormone secretion GO:0046879 39 21 0,000 0,02510711 0,03737762 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02510711 0,03735485 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02510711 0,03733212 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02510711 0,03730941 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02510711 0,03728673 ! ovarian follicle development GO:0001541 39 21 0,000 0,02510711 0,03726408 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02510711 0,03724145 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02510711 0,03721885 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02510711 0,03719628 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02510711 0,03717374 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02510711 0,03715122 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02510711 0,03712873 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02510711 0,03710627 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02510711 0,03708384 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02510711 0,03706143 ! sensory perception of pain GO:0019233 33 21 0,000 0,02510711 0,03703905 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02510711 0,0370167 ! diencephalon development GO:0021536 36 21 0,000 0,02510711 0,03699437 ! collagen fibril organization GO:0030199 62 21 0,000 0,02510711 0,03697207 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02510711 0,0369498 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02510711 0,03692756 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02510711 0,03690534 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02510711 0,03688314 ! collagen catabolic process GO:0030574 29 21 0,000 0,02510711 0,03686098 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02510711 0,03683884 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02510711 0,03681673 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02510711 0,03679464 ! actin filament-based movement GO:0030048 47 21 0,000 0,02510711 0,03677258 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02510711 0,03675055 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,0262872 0,03845487 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,0262872 0,03843186 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,0262872 0,03840887 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,0262872 0,03838591 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,0262872 0,03836298 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,0262872 0,03834008 ! microtubule-based transport GO:0010970 59 22 0,000 0,0262872 0,0383172 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,0262872 0,03829435 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,0262872 0,03827153 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,0262872 0,03824874 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,0262872 0,03822597 ! cellular response to starvation GO:0009267 37 22 0,000 0,0262872 0,03820323 ! vacuolar transport GO:0007034 41 22 0,000 0,0262872 0,03818052 ! central nervous system neuron development GO:0021954 47 22 0,000 0,0262872 0,03815783 ! fucose metabolic process GO:0006004 44 22 0,000 0,0262872 0,03813517 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,0262872 0,03811254 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,0262872 0,03808994 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,0262872 0,03806736 ! ureteric bud development GO:0001657 50 22 0,000 0,0262872 0,03804481 ! stem cell differentiation GO:0048863 57 22 0,000 0,0262872 0,03802228 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,0262872 0,03799978 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,0262872 0,03797731 ! cytolysis GO:0019835 27 22 0,000 0,0262872 0,03795487 ! renal system process GO:0003014 42 22 0,000 0,0262872 0,03793245 ! vasodilation GO:0042311 40 22 0,000 0,0262872 0,03791005 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,0262872 0,03788769 ! G1 phase GO:0051318 44 22 0,000 0,0262872 0,03786535 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,0262872 0,03784304 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,0262872 0,03782075 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,0262872 0,03779849 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,0262872 0,03777625 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,0262872 0,03775405 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,0262872 0,03773186 ! sarcomere organization GO:0045214 32 22 0,000 0,0262872 0,03770971 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,0262872 0,03768758 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,0262872 0,03766547 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,0262872 0,0376434 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,0262872 0,03762134 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,0262872 0,03759932 ! gut development GO:0048565 44 22 0,000 0,0262872 0,03757732 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,0262872 0,03755534 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,0262872 0,03753339 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,0262872 0,03751147 ! protein stabilization GO:0050821 41 22 0,000 0,0262872 0,03748957 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,0274659 0,03914772 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,0274659 0,03912489 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,0274659 0,03910209 ! gluconeogenesis GO:0006094 38 23 0,000 0,0274659 0,03907932 ! glycerol metabolic process GO:0006071 40 23 0,000 0,0274659 0,03905657 ! viral genome replication GO:0019079 44 23 0,000 0,0274659 0,03903385 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,0274659 0,03901116 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,0274659 0,03898849 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,0274659 0,03896585 ! regeneration GO:0031099 42 23 0,000 0,0274659 0,03894323 ! axis specification GO:0009798 43 23 0,000 0,0274659 0,03892064 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,0274659 0,03889808 ! response to ethanol GO:0045471 47 23 0,000 0,0274659 0,03887554 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,0274659 0,03885303 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,0274659 0,03883055 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,0274659 0,03880809 ! peroxisome organization GO:0007031 43 23 0,000 0,0274659 0,03878566 ! lysosome organization GO:0007040 47 23 0,000 0,0274659 0,03876325 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,0274659 0,03874087 ! vesicle targeting GO:0006903 49 23 0,000 0,0274659 0,03871852 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,0274659 0,03869619 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,0274659 0,03867388 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,0274659 0,03865161 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,0274659 0,03862935 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,0274659 0,03860713 ! DNA modification GO:0006304 36 23 0,000 0,0274659 0,03858493 ! fatty acid transport GO:0015908 47 23 0,000 0,0274659 0,03856275 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,0274659 0,0385406 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,0274659 0,03851848 ! hormone transport GO:0009914 41 23 0,000 0,0274659 0,03849638 ! cell-cell recognition GO:0009988 28 23 0,000 0,0274659 0,03847431 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,0274659 0,03845226 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,0274659 0,03843023 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0286432 0,04005457 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0286432 0,04003166 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,0286432 0,04000877 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,0286432 0,03998591 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0286432 0,03996307 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0286432 0,03994026 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0286432 0,03991748 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0286432 0,03989472 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0286432 0,03987199 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,0286432 0,03984928 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0286432 0,0398266 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,0286432 0,03980395 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0286432 0,03978132 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0286432 0,03975871 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0286432 0,03973614 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,0286432 0,03971359 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0286432 0,03969106 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,0286432 0,03966856 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0286432 0,03964608 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0286432 0,03962363 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,0286432 0,03960121 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0286432 0,03957881 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0286432 0,03955644 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0286432 0,03953409 ! membrane depolarization GO:0051899 45 24 0,000 0,0286432 0,03951177 ! pallium development GO:0021543 56 24 0,000 0,0286432 0,03948947 ! oogenesis GO:0048477 44 24 0,000 0,0286432 0,0394672 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0286432 0,03944495 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0286432 0,03942273 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,0286432 0,03940053 ! platelet activation GO:0030168 41 24 0,000 0,0286432 0,03937836 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0286432 0,03935621 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0286432 0,03933409 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0286432 0,03931199 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0286432 0,03928991 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0286432 0,03926787 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0286432 0,03924584 ! regulation of amine transport GO:0051952 41 24 0,000 0,0286432 0,03922384 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,0286432 0,03920187 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02981911 0,0407884 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02981911 0,04076558 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,02981911 0,04074278 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02981911 0,04072 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02981911 0,04069726 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02981911 0,04067453 ! phototransduction GO:0007602 37 25 0,000 0,02981911 0,04065183 ! keratinization GO:0031424 37 25 0,000 0,02981911 0,04062916 ! vasculogenesis GO:0001570 49 25 0,000 0,02981911 0,04060651 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,02981911 0,04058389 ! vacuole organization GO:0007033 49 25 0,000 0,02981911 0,0405613 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02981911 0,04053872 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02981911 0,04051618 ! receptor metabolic process GO:0043112 53 25 0,000 0,02981911 0,04049366 ! chromosome condensation GO:0030261 48 25 0,000 0,02981911 0,04047116 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02981911 0,04044869 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02981911 0,04042624 ! interaction with host GO:0051701 66 25 0,000 0,02981911 0,04040382 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02981911 0,04038142 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02981911 0,04035905 ! immunoglobulin production GO:0002377 62 25 0,000 0,02981911 0,0403367 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02981911 0,04031438 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,02981911 0,04029208 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02981911 0,04026981 ! liver development GO:0001889 55 25 0,000 0,02981911 0,04024756 ! protein tetramerization GO:0051262 57 25 0,000 0,02981911 0,04022534 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03099363 0,04178667 ! myelination GO:0042552 50 26 0,000 0,03099363 0,04176362 ! initiation of viral infection GO:0019059 60 26 0,000 0,03099363 0,0417406 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03099363 0,0417176 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03099363 0,04169463 ! molting cycle process GO:0022404 52 26 0,000 0,03099363 0,04167168 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03099363 0,04164876 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,03099363 0,04162586 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,03099363 0,04160299 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,03099363 0,04158014 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,03099363 0,04155732 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,03099363 0,04153453 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03099363 0,04151175 ! digestive system process GO:0022600 49 26 0,000 0,03099363 0,04148901 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03099363 0,04146629 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,03099363 0,04144359 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,03099363 0,04142092 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,03099363 0,04139827 ! neural crest cell development GO:0014032 59 26 0,000 0,03099363 0,04137565 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03099363 0,04135305 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03099363 0,04133048 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03099363 0,04130793 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03099363 0,04128541 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03099363 0,04126291 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03099363 0,04124044 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03099363 0,04121799 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,03099363 0,04119556 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,03099363 0,04117316 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03099363 0,04115078 ! blastocyst development GO:0001824 50 26 0,000 0,03099363 0,04112843 ! telomere organization GO:0032200 46 26 0,000 0,03099363 0,0411061 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03099363 0,0410838 ! neural tube closure GO:0001843 58 26 0,000 0,03099363 0,04106152 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,03099363 0,04103926 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03099363 0,04101703 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03216676 0,04254651 ! embryonic pattern specification GO:0009880 49 27 0,000 0,03216676 0,04252348 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,03216676 0,04250049 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,03216676 0,04247751 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,03216676 0,04245456 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,03216676 0,04243164 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,03216676 0,04240874 ! iron ion transport GO:0006826 65 27 0,000 0,03216676 0,04238587 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,03216676 0,04236302 ! superoxide metabolic process GO:0006801 41 27 0,000 0,03216676 0,04234019 ! tube lumen formation GO:0035148 59 27 0,000 0,03216676 0,04231739 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,03216676 0,04229462 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,03216676 0,04227187 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,03216676 0,04224914 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,03216676 0,04222644 ! response to starvation GO:0042594 47 27 0,000 0,03216676 0,04220376 ! response to toxin GO:0009636 49 27 0,000 0,03216676 0,04218111 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,03216676 0,04215848 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,03216676 0,04213587 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,03216676 0,04211329 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,03216676 0,04209073 ! leukocyte proliferation GO:0070661 59 27 0,000 0,03216676 0,0420682 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,03216676 0,04204569 ! neuron fate commitment GO:0048663 52 28 0,000 0,03333851 0,04355399 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,03333851 0,04353072 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,03333851 0,04350746 ! protein amino acid acylation GO:0043543 59 28 0,000 0,03333851 0,04348423 ! vesicle docking GO:0048278 55 28 0,000 0,03333851 0,04346103 ! circadian rhythm GO:0007623 56 28 0,000 0,03333851 0,04343785 ! dendrite development GO:0016358 67 28 0,000 0,03333851 0,0434147 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03333851 0,04339157 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03333851 0,04336846 ! base-excision repair GO:0006284 41 28 0,000 0,03333851 0,04334538 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03333851 0,04332232 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03333851 0,04329929 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03333851 0,04327629 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03333851 0,0432533 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,03333851 0,04323035 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03333851 0,04320741 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03333851 0,0431845 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03333851 0,04316162 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03333851 0,04313876 ! lipid oxidation GO:0034440 48 28 0,000 0,03333851 0,04311592 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,03333851 0,04309311 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03333851 0,04307032 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,03450886 0,04455875 ! translational initiation GO:0006413 66 29 0,000 0,03450886 0,04453521 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03450886 0,0445117 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03450886 0,04448821 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03450886 0,04446474 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,03450886 0,0444413 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03450886 0,04441789 ! primary neural tube formation GO:0014020 61 29 0,000 0,03450886 0,0443945 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03450886 0,04437113 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03450886 0,04434779 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03450886 0,04432448 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,03450886 0,04430119 ! somitogenesis GO:0001756 52 29 0,000 0,03450886 0,04427792 ! synaptogenesis GO:0007416 46 29 0,000 0,03450886 0,04425467 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,03450886 0,04423146 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03450886 0,04420826 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03450886 0,04418509 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,03567784 0,04565791 ! phenol metabolic process GO:0018958 56 30 0,000 0,03567784 0,04563401 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03567784 0,04561013 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03567784 0,04558628 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03567784 0,04556245 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03567784 0,04553864 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03567784 0,04551486 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03567784 0,04549111 ! acute-phase response GO:0006953 50 30 0,000 0,03567784 0,04546738 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03567784 0,04544367 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03567784 0,04541999 ! myofibril assembly GO:0030239 50 30 0,000 0,03567784 0,04539633 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,03567784 0,0453727 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,03567784 0,04534909 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03567784 0,04532551 ! cell fate determination GO:0001709 64 30 0,000 0,03567784 0,04530195 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03567784 0,04527842 ! phospholipid transport GO:0015914 65 30 0,000 0,03567784 0,04525491 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03567784 0,04523143 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03567784 0,04520797 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,03567784 0,04518453 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03567784 0,04516112 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03567784 0,04513773 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,03567784 0,04511437 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,03684543 0,04656668 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,03684543 0,0465426 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,03684543 0,04651855 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,03684543 0,04649452 ! cell junction assembly GO:0034329 85 31 0,000 0,03684543 0,04647051 ! regulation of innate immune response GO:0045088 57 31 0,000 0,03684543 0,04644654 ! ovulation cycle process GO:0022602 55 31 0,000 0,03684543 0,04642258 ! peptide transport GO:0015833 60 31 0,000 0,03684543 0,04639865 ! male gonad development GO:0008584 56 31 0,000 0,03684543 0,04637475 ! iron ion homeostasis GO:0055072 60 31 0,000 0,03684543 0,04635087 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,03684543 0,04632701 ! detection of light stimulus GO:0009583 44 31 0,000 0,03684543 0,04630318 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,03684543 0,04627938 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,03684543 0,04625559 ! natural killer cell activation GO:0030101 50 31 0,000 0,03684543 0,04623184 ! ensheathment of neurons GO:0007272 64 31 0,000 0,03684543 0,0462081 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,03684543 0,0461844 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,03684543 0,04616071 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,03684543 0,04613705 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,03684543 0,04611341 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,03801164 0,04754861 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,03801164 0,04752428 ! collagen metabolic process GO:0032963 49 32 0,000 0,03801164 0,04749997 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,03801164 0,04747568 ! spindle organization GO:0007051 50 32 0,000 0,03801164 0,04745143 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,03801164 0,04742719 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,03801164 0,04740298 ! metanephros development GO:0001656 81 32 0,000 0,03801164 0,0473788 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,03801164 0,04735463 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,03801164 0,0473305 ! muscle cell development GO:0055001 52 32 0,000 0,03801164 0,04730639 ! mesoderm formation GO:0001707 73 32 0,000 0,03801164 0,0472823 ! ovulation cycle GO:0042698 57 32 0,000 0,03801164 0,04725824 ! peripheral nervous system development GO:0007422 68 32 0,000 0,03801164 0,0472342 ! BMP signaling pathway GO:0030509 71 32 0,000 0,03801164 0,04721019 ! hindbrain development GO:0030902 65 32 0,000 0,03801164 0,0471862 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,03801164 0,04716223 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,03801164 0,04713829 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,03801164 0,04711438 ! gene silencing GO:0016458 71 32 0,000 0,03801164 0,04709049 ! regulation of pH GO:0006885 56 33 0,000 0,03917647 0,04850893 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,03917647 0,04848436 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,03917647 0,04845981 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,03917647 0,04843528 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,03917647 0,04841079 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,03917647 0,04838631 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,03917647 0,04836186 ! response to ionizing radiation GO:0010212 74 33 0,000 0,03917647 0,04833744 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,03917647 0,04831304 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,03917647 0,04828866 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,03917647 0,04826431 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,03917647 0,04823998 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,03917647 0,04821568 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,03917647 0,0481914 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,03917647 0,04816715 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,04033993 0,04957266 ! glial cell differentiation GO:0010001 67 34 0,000 0,04033993 0,04954773 ! post-embryonic development GO:0009791 76 34 0,000 0,04033993 0,04952283 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,04033993 0,04949796 ! cholesterol transport GO:0030301 62 34 0,000 0,04033993 0,04947311 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,04033993 0,04944829 ! spliceosome assembly GO:0000245 75 34 0,000 0,04033993 0,04942349 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,04033993 0,04939872 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,04033993 0,04937397 ! formation of primary germ layer GO:0001704 76 34 0,000 0,04033993 0,04934924 ! cell fate specification GO:0001708 56 34 0,000 0,04033993 0,04932454 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,04033993 0,04929987 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,04033993 0,04927522 ! adult locomotory behavior GO:0008344 62 34 0,000 0,04033993 0,0492506 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,04033993 0,04922599 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,041502 0,05061877 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,041502 0,05059351 ! negative regulation of secretion GO:0051048 68 35 0,000 0,041502 0,05056828 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,041502 0,05054307 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,041502 0,05051789 ! membrane docking GO:0022406 69 35 0,000 0,041502 0,05049273 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,041502 0,05046759 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,041502 0,05044249 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,041502 0,0504174 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,041502 0,05039234 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,041502 0,05036731 ! ceramide metabolic process GO:0006672 72 35 0,000 0,041502 0,0503423 ! telencephalon development GO:0021537 81 35 0,000 0,041502 0,05031732 ! sterol transport GO:0015918 63 35 0,000 0,041502 0,05029236 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,041502 0,05026743 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,041502 0,05024252 ! placenta development GO:0001890 53 35 0,000 0,041502 0,05021763 ! vesicle localization GO:0051648 70 35 0,000 0,041502 0,05019277 ! regulation of muscle development GO:0048634 82 36 0,000 0,04266271 0,051571 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,04266271 0,0515455 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,04266271 0,05152002 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,04266271 0,05149456 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,04266271 0,05146913 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,04266271 0,05144373 ! positive regulation of cell development GO:0010720 85 36 0,000 0,04266271 0,05141835 ! regulation of proteolysis GO:0030162 77 36 0,000 0,04266271 0,051393 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,04266271 0,05136767 ! aerobic respiration GO:0009060 56 36 0,000 0,04266271 0,05134236 ! cytokine production GO:0001816 68 36 0,000 0,04266271 0,05131708 ! embryonic organ development GO:0048568 67 36 0,000 0,04266271 0,05129183 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,04266271 0,0512666 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,04382204 0,05263384 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,04382204 0,05260798 ! sister chromatid segregation GO:0000819 65 37 0,000 0,04382204 0,05258214 ! odontogenesis GO:0042476 74 37 0,000 0,04382204 0,05255633 ! actomyosin structure organization GO:0031032 68 37 0,000 0,04382204 0,05253054 ! tissue remodeling GO:0048771 78 37 0,000 0,04382204 0,05250478 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,04382204 0,05247904 ! female gonad development GO:0008585 71 37 0,000 0,04382204 0,05245333 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,04382204 0,05242764 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,04382204 0,05240198 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,04382204 0,05237634 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,04498 0,05373405 ! meiosis I GO:0007127 74 38 0,000 0,04498 0,05370779 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,04498 0,05368155 ! organic anion transport GO:0015711 82 38 0,000 0,04498 0,05365534 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,04498 0,05362915 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,04498 0,05360299 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,04498 0,05357686 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,04498 0,05355075 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,04498 0,05352466 ! regulation of protein stability GO:0031647 77 38 0,000 0,04498 0,0534986 ! spermatid development GO:0007286 69 38 0,000 0,04498 0,05347257 ! glycogen metabolic process GO:0005977 63 38 0,000 0,04498 0,05344656 ! pigment metabolic process GO:0042440 87 38 0,000 0,04498 0,05342058 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,04498 0,05339462 ! neural tube formation GO:0001841 79 38 0,000 0,04498 0,05336869 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,04613659 0,05471441 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,04613659 0,05468786 ! negative regulation of binding GO:0051100 71 39 0,000 0,04613659 0,05466134 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,04613659 0,05463484 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,04613659 0,05460837 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,04613659 0,05458193 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,04613659 0,05455551 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,04613659 0,05452912 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,04613659 0,05450275 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,04613659 0,0544764 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,04613659 0,05445009 ! glucan metabolic process GO:0044042 64 39 0,000 0,04613659 0,0544238 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,04729181 0,0557596 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,04729181 0,0557327 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,04729181 0,05570583 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,04729181 0,05567898 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,04729181 0,05565216 ! lipid homeostasis GO:0055088 75 40 0,000 0,04729181 0,05562537 ! mismatch repair GO:0006298 58 40 0,000 0,04729181 0,0555986 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,04729181 0,05557185 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,04729181 0,05554514 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,04729181 0,05551845 ! RNA export from nucleus GO:0006405 61 41 0,000 0,04844566 0,0568457 ! mRNA catabolic process GO:0006402 79 41 0,000 0,04844566 0,05681841 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,04844566 0,05679115 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,04844566 0,05676391 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,04844566 0,0567367 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,04844566 0,05670951 ! gliogenesis GO:0042063 91 41 0,000 0,04844566 0,05668235 ! feeding behavior GO:0007631 69 41 0,000 0,04844566 0,05665522 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,04844566 0,05662811 ! mesenchymal cell development GO:0014031 94 41 0,000 0,04844566 0,05660103 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,04844566 0,05657397 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,04844566 0,05654694 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,04844566 0,05651994 ! spermatid differentiation GO:0048515 73 41 0,000 0,04844566 0,05649296 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,04844566 0,05646601 ! RNA modification GO:0009451 64 41 0,000 0,04844566 0,05643908 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,04959815 0,05775419 ! ear morphogenesis GO:0042471 64 42 0,000 0,04959815 0,05772667 ! organic ether metabolic process GO:0018904 59 42 0,000 0,04959815 0,05769918 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,04959815 0,05767172 ! T cell differentiation GO:0030217 93 42 0,000 0,04959815 0,05764428 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,04959815 0,05761687 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,04959815 0,05758949 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,04959815 0,05756213 ! regulation of protein secretion GO:0050708 77 42 0,000 0,04959815 0,0575348 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,04959815 0,05750749 ! cytokinesis GO:0000910 84 42 0,000 0,04959815 0,05748021 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,04959815 0,05745296 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,05074928 0,05875852 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,05074928 0,05873069 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,05074928 0,05870288 ! regulation of tube size GO:0035150 76 43 0,000 0,05074928 0,0586751 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,05074928 0,05864734 ! glucose transport GO:0015758 66 43 0,000 0,05074928 0,05861962 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,05074928 0,05859191 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,05074928 0,05856424 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,05074928 0,05853658 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,05074928 0,05850896 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,05074928 0,05848136 ! segmentation GO:0035282 78 43 0,000 0,05074928 0,05845379 ! ion transmembrane transport GO:0034220 79 43 0,000 0,05074928 0,05842624 ! neuron migration GO:0001764 85 43 0,000 0,05074928 0,05839872 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,05074928 0,05837123 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,05189904 0,05966558 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,05189904 0,05963752 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,05189904 0,05960948 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,05189904 0,05958147 ! hexose transport GO:0008645 68 44 0,000 0,05189904 0,05955348 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,05189904 0,05952552 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,05189904 0,05949759 ! double-strand break repair GO:0006302 85 44 0,000 0,05189904 0,05946968 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,05304745 0,06075711 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,05304745 0,06072864 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,05304745 0,06070019 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,05304745 0,06067177 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,05304745 0,06064338 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,05304745 0,06061502 ! B cell differentiation GO:0030183 124 45 0,000 0,05304745 0,06058668 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,05304745 0,06055837 ! female gamete generation GO:0007292 71 45 0,000 0,05304745 0,06053008 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,05304745 0,06050183 ! developmental growth GO:0048589 88 45 0,000 0,05304745 0,06047359 ! maintenance of location in cell GO:0051651 101 45 0,000 0,05304745 0,06044539 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,05419449 0,06172361 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,05419449 0,06169485 ! glycolysis GO:0006096 71 46 0,000 0,05419449 0,06166611 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,05419449 0,0616374 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,05419449 0,06160872 ! leukocyte migration GO:0050900 75 46 0,000 0,05419449 0,06158007 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,05419449 0,06155144 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,05419449 0,06152284 ! pigmentation GO:0043473 103 46 0,000 0,05419449 0,06149426 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,05419449 0,06146571 ! neural tube development GO:0021915 91 47 0,000 0,05534018 0,06273599 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,05534018 0,06270689 ! response to insulin stimulus GO:0032868 98 47 0,000 0,05534018 0,06267782 ! positive regulation of defense response GO:0031349 88 48 0,000 0,05648451 0,06394424 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,05648451 0,06391462 ! mitochondrial transport GO:0006839 94 48 0,000 0,05648451 0,06388503 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,05648451 0,06385547 ! cellular component disassembly GO:0022411 89 48 0,000 0,05648451 0,06382593 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,05648451 0,06379642 ! endosome transport GO:0016197 127 48 0,000 0,05648451 0,06376694 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,05648451 0,06373749 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,05648451 0,06370806 ! male sex differentiation GO:0046661 93 48 0,000 0,05648451 0,06367866 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,05648451 0,06364929 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,05648451 0,06361995 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,05648451 0,06359063 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,05648451 0,06356134 ! methylation GO:0032259 97 48 0,000 0,05648451 0,06353207 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,05762749 0,06478783 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,05762749 0,06475803 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,05762749 0,06472826 ! JNK cascade GO:0007254 106 49 0,000 0,05762749 0,06469851 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,05762749 0,06466879 ! protein homooligomerization GO:0051260 84 49 0,000 0,05762749 0,0646391 ! regulation of action potential GO:0001508 102 50 0,000 0,05876912 0,06588938 ! regulation of ion transport GO:0043269 86 50 0,000 0,05876912 0,06585915 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,05876912 0,06582896 ! endocrine system development GO:0035270 109 50 0,000 0,05876912 0,06579879 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,05876912 0,06576864 ! activation of caspase activity GO:0006919 95 50 0,000 0,05876912 0,06573853 ! regulation of ossification GO:0030278 123 50 0,000 0,05876912 0,06570844 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,05876912 0,06567839 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,05876912 0,06564835 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,05876912 0,06561835 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,05990939 0,06686096 ! viral infectious cycle GO:0019058 104 51 0,000 0,05990939 0,06683043 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,05990939 0,06679993 ! peptide metabolic process GO:0006518 80 51 0,000 0,05990939 0,06676945 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,05990939 0,06673901 ! positive regulation of binding GO:0051099 88 52 0,000 0,06104832 0,06797677 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,06104832 0,0679458 ! Notch signaling pathway GO:0007219 111 52 0,000 0,06104832 0,06791486 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,06104832 0,06788395 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,06104832 0,06785307 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,06104832 0,06782221 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,06104832 0,06779138 ! excretion GO:0007588 87 52 0,000 0,06104832 0,06776058 ! histone modification GO:0016570 104 52 0,000 0,06104832 0,06772981 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,06104832 0,06769906 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,06104832 0,06766835 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,06104832 0,06763766 ! amino acid activation GO:0043038 98 52 0,000 0,06104832 0,067607 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,0621859 0,06883559 ! positive regulation of growth GO:0045927 96 53 0,000 0,0621859 0,06880441 ! inner ear development GO:0048839 89 53 0,000 0,0621859 0,06877327 ! chromatin remodeling GO:0006338 122 53 0,000 0,0621859 0,06874215 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,0621859 0,06871106 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,0621859 0,06867999 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,0621859 0,06864896 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 0,000 0,0621859 0,06861795 ! synapse organization GO:0050808 102 53 0,000 0,0621859 0,06858697 ! regulation of translational initiation GO:0006446 87 54 0,000 0,06332213 0,06980865 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,06332213 0,06977716 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,06332213 0,0697457 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,06332213 0,06971427 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,06332213 0,06968286 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,06332213 0,06965149 ! membrane fusion GO:0006944 122 54 0,000 0,06332213 0,06962014 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,06332213 0,06958883 ! covalent chromatin modification GO:0016569 115 54 0,000 0,06332213 0,06955754 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,06332213 0,06952627 ! regulation of cell shape GO:0008360 142 54 0,000 0,06332213 0,06949504 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,06332213 0,06946383 ! RNA catabolic process GO:0006401 103 55 0,000 0,06445701 0,07067706 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,06445701 0,07064535 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,06445701 0,07061367 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,06445701 0,07058202 ! cell recognition GO:0008037 98 55 0,000 0,06445701 0,0705504 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,06445701 0,0705188 ! cell maturation GO:0048469 107 55 0,000 0,06445701 0,07048724 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,06445701 0,0704557 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,06559056 0,07166267 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,06559056 0,07163064 ! glucose catabolic process GO:0006007 88 56 0,000 0,06559056 0,07159863 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,06559056 0,07156665 ! RNA elongation GO:0006354 90 56 0,000 0,06559056 0,0715347 ! chloride transport GO:0006821 102 57 0,000 0,06672276 0,07273704 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,06672276 0,0727046 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,06672276 0,07267218 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,06672276 0,0726398 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,06672276 0,07260744 ! heart morphogenesis GO:0003007 105 57 0,000 0,06672276 0,07257511 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,06672276 0,07254282 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,06672276 0,07251055 ! regulation of actin filament length GO:0030832 118 58 0,000 0,06785362 0,07370672 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,06785362 0,07367396 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,06785362 0,07364123 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,06785362 0,07360853 ! gastrulation GO:0007369 122 58 0,000 0,06785362 0,07357586 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,06785362 0,07354321 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,06785362 0,0735106 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,06785362 0,07347802 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,06785362 0,07344546 ! maintenance of location GO:0051235 124 58 0,000 0,06785362 0,07341293 ! nuclear export GO:0051168 110 59 0,000 0,06898315 0,07460196 ! establishment of organelle localization GO:0051656 122 59 0,000 0,06898315 0,07456895 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,07011134 0,07575497 ! lipid modification GO:0030258 112 60 0,000 0,07011134 0,07572148 ! DNA catabolic process GO:0006308 94 60 0,000 0,07011134 0,07568802 ! regulation of endocytosis GO:0030100 104 60 0,000 0,07011134 0,07565459 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,07011134 0,07562119 ! adult behavior GO:0030534 104 60 0,000 0,07011134 0,07558782 ! kidney development GO:0001822 133 60 0,000 0,07011134 0,07555447 ! positive regulation of secretion GO:0051047 110 61 0,000 0,07123819 0,07673496 ! regulation of cellular component size GO:0032535 125 61 0,000 0,07123819 0,07670114 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,07123819 0,07666735 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,07123819 0,07663359 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,07123819 0,07659986 ! regulation of heart contraction GO:0008016 123 61 0,000 0,07123819 0,07656616 ! camera-type eye development GO:0043010 126 61 0,000 0,07123819 0,07653249 ! proton transport GO:0015992 117 61 0,000 0,07123819 0,07649885 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,07123819 0,07646524 ! viral reproductive process GO:0022415 132 62 0,000 0,07236371 0,07763923 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,07236371 0,07760515 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,07236371 0,0775711 ! tRNA processing GO:0008033 102 62 0,000 0,07236371 0,07753708 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,07236371 0,07750308 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,07348789 0,07867262 ! regulation of mitosis GO:0007088 112 63 0,000 0,07348789 0,07863816 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,07348789 0,07860373 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,07348789 0,07856933 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,07348789 0,07853496 ! hydrogen transport GO:0006818 121 64 0,000 0,07461075 0,07970007 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,07461075 0,07966523 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,07461075 0,07963043 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,07461075 0,07959566 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,07461075 0,07956091 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,07573227 0,08072162 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,07573227 0,08068641 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,07573227 0,08065124 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,07573227 0,0806161 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,07573227 0,08058099 ! ear development GO:0043583 114 66 0,000 0,07685247 0,0817373 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,07685247 0,08170173 ! gonad development GO:0008406 115 66 0,000 0,07685247 0,0816662 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,07685247 0,08163069 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,07797134 0,08278313 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,07797134 0,08274717 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,07797134 0,08271124 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,07797134 0,08267534 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,07797134 0,08263948 ! secondary metabolic process GO:0019748 125 67 0,000 0,07797134 0,08260364 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,07797134 0,08256783 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,07908889 0,08371497 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,07908889 0,08367872 ! hexose catabolic process GO:0019320 113 68 0,000 0,07908889 0,08364249 ! extracellular matrix organization GO:0030198 146 68 0,000 0,07908889 0,0836063 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,07908889 0,08357014 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,07908889 0,08353401 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,07908889 0,08349791 ! viral reproduction GO:0016032 142 68 0,000 0,07908889 0,08346184 ! regulation of lipase activity GO:0060191 137 68 0,000 0,07908889 0,0834258 ! adaptive immune response GO:0002250 126 68 0,000 0,07908889 0,0833898 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell size GO:0045792 144 69 0,000 0,08020511 0,08453024 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,08020511 0,08449379 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,08020511 0,08445737 ! lung development GO:0030324 165 69 0,000 0,08020511 0,08442098 ! urogenital system development GO:0001655 149 69 0,000 0,08020511 0,08438462 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,08020511 0,0843483 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,08020511 0,084312 ! developmental maturation GO:0021700 128 69 0,000 0,08020511 0,08427574 ! single fertilization GO:0007338 83 69 0,000 0,08020511 0,08423951 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,08132002 0,08537379 ! cell redox homeostasis GO:0045454 114 70 0,000 0,08132002 0,08533711 ! germ cell development GO:0007281 133 70 0,000 0,08132002 0,08530047 ! activation of immune response GO:0002253 120 70 0,000 0,08132002 0,08526386 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,08132002 0,08522729 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,0824336 0,08635733 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,0824336 0,08632031 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,0824336 0,08628333 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,0824336 0,08624638 ! appendage morphogenesis GO:0035107 150 72 0,000 0,08354586 0,08737267 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,08354586 0,08733528 ! respiratory tube development GO:0030323 171 72 0,000 0,08354586 0,08729792 ! B cell activation GO:0042113 179 72 0,000 0,08354586 0,0872606 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,08354586 0,08722331 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,08354586 0,08718605 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,08354586 0,08714882 ! appendage development GO:0048736 151 73 0,000 0,08465681 0,08826999 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,08465681 0,08823233 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,08465681 0,08819471 ! regulation of immune effector process GO:0002697 156 73 0,000 0,08465681 0,08815712 ! acute inflammatory response GO:0002526 118 74 0,000 0,08576644 0,08927457 ! amino acid transport GO:0006865 148 74 0,000 0,08576644 0,08923655 ! regulation of caspase activity GO:0043281 136 74 0,000 0,08576644 0,08919856 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,08576644 0,08916061 ! respiratory system development GO:0060541 175 74 0,000 0,08576644 0,08912268 ! organelle localization GO:0051640 155 74 0,000 0,08576644 0,08908479 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,08687476 0,09019764 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,08687476 0,09015932 ! reproductive structure development GO:0048608 131 75 0,000 0,08687476 0,09012104 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,08687476 0,09008279 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,08687476 0,09004457 ! axon guidance GO:0007411 162 75 0,000 0,08687476 0,09000638 ! rhythmic process GO:0048511 142 75 0,000 0,08687476 0,08996823 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,08798177 0,09107604 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,08798177 0,09103747 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,08798177 0,09099892 ! regulation of blood pressure GO:0008217 134 76 0,000 0,08798177 0,09096041 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,08798177 0,09092194 ! amine catabolic process GO:0009310 136 77 0,000 0,08908746 0,09202565 ! neurotransmitter transport GO:0006836 142 77 0,000 0,08908746 0,09198676 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,08908746 0,0919479 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,08908746 0,09190907 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,08908746 0,09187027 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,08908746 0,09183151 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,08908746 0,09179278 ! regulation of catabolic process GO:0009894 173 77 0,000 0,08908746 0,09175408 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,09019185 0,09285237 ! antigen processing and presentation GO:0019882 117 78 0,000 0,09019185 0,09281326 ! fertilization GO:0009566 99 78 0,000 0,09019185 0,09277418 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,09019185 0,09273514 ! blood coagulation GO:0007596 151 79 0,000 0,09129493 0,09382983 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,09129493 0,09379037 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,09129493 0,09375095 ! protein oligomerization GO:0051259 149 79 0,000 0,09129493 0,09371156 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,0923967 0,09480266 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,0923967 0,09476286 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,0923967 0,09472309 ! meiosis GO:0007126 143 81 0,000 0,09349716 0,09581106 GO:0051327|M phase of meiotic cell cycle, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,09349716 0,09577089 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,09459633 0,09685617 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,09459633 0,0968156 ! protein import into nucleus GO:0006606 174 82 0,000 0,09459633 0,09677505 ! meiotic cell cycle GO:0051321 144 82 0,000 0,09459633 0,09673454 ! exocytosis GO:0006887 153 83 0,000 0,09569419 0,09781628 ! response to drug GO:0042493 149 83 0,000 0,09569419 0,09777537 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,09569419 0,09773449 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,09569419 0,09769365 ! nuclear import GO:0051170 177 83 0,000 0,09569419 0,09765284 ! inorganic anion transport GO:0015698 156 83 0,000 0,09569419 0,09761207 ! T cell activation GO:0042110 189 84 0,000 0,09679075 0,0986894 ! response to nutrient GO:0007584 135 84 0,000 0,09679075 0,09864823 ! digestion GO:0007586 130 84 0,000 0,09679075 0,09860709 ! hemostasis GO:0007599 165 85 0,000 0,09788601 0,09968134 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,09788601 0,0996398 ! negative regulation of growth GO:0045926 168 85 0,000 0,09788601 0,0995983 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,09788601 0,09955684 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,09788601 0,09951541 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,10007265 0,10169612 ! mitochondrion organization GO:0007005 159 87 0,000 0,10007265 0,10165383 ! nucleosome assembly GO:0006334 126 87 0,000 0,10007265 0,10161158 ! regulation of protein transport GO:0051223 165 87 0,000 0,10007265 0,10156937 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 0,000 0,10116402 0,10263443 ! sensory perception of smell GO:0007608 117 88 0,000 0,10116402 0,10259182 ! chromatin assembly GO:0031497 128 88 0,000 0,10116402 0,10254925 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,10116402 0,10250672 ! regulation of DNA binding GO:0051101 167 89 0,000 0,1022541 0,10356831 ! tube morphogenesis GO:0035239 194 89 0,000 0,1022541 0,10352539 ! cellular defense response GO:0006968 123 89 0,000 0,1022541 0,10348251 ! protein localization in nucleus GO:0034504 192 89 0,000 0,1022541 0,10343966 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,10334289 0,1044978 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,10334289 0,10445457 ! gland development GO:0048732 220 91 0,000 0,10443039 0,10551011 ! defense response to bacterium GO:0042742 112 91 0,000 0,10443039 0,1054665 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,10551661 0,10651945 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,10660153 0,10757024 ! amine transport GO:0015837 181 93 0,000 0,10660153 0,10752582 ! vitamin metabolic process GO:0006766 153 93 0,000 0,10660153 0,10748145 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,10768517 0,10852924 ! female pregnancy GO:0007565 166 94 0,000 0,10768517 0,10848448 ! sterol metabolic process GO:0016125 166 94 0,000 0,10768517 0,10843977 ! regulation of membrane potential GO:0042391 179 94 0,000 0,10768517 0,10839509 ! regulation of defense response GO:0031347 171 95 0,000 0,10876753 0,10943949 ! nucleosome organization GO:0034728 143 95 0,000 0,10876753 0,10939443 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,10876753 0,10934941 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,10876753 0,10930443 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,10876753 0,10925949 ! sex differentiation GO:0007548 171 96 0,000 0,1098486 0,1103001 ! regulation of T cell activation GO:0050863 175 96 0,000 0,1098486 0,11025478 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,1109284 0,11129284 ! transcription initiation GO:0006352 171 97 0,000 0,1109284 0,11124716 ! regulation of protein localization GO:0032880 188 97 0,000 0,1109284 0,11120151 ! leukocyte differentiation GO:0002521 232 98 0,000 0,11200691 0,11223662 ! forebrain development GO:0030900 210 98 0,000 0,11200691 0,1121906 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,11416011 0,11430047 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,11416011 0,11425364 ! positive regulation of immune response GO:0050778 175 100 0,000 0,11416011 0,11420685 ! hormone metabolic process GO:0042445 171 100 0,000 0,11416011 0,11416011