pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/6426-8-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 1,191E-07 2,865E-04 ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 6,077E-06 7,311E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 6,077E-06 4,874E-03 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 6,077E-06 3,655E-03 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 6,077E-06 2,924E-03 GO:0032862|activation of Rho GTPase activity, ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 6,599E-06 2,646E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,699E-05 5,84E-03 ! DNA topological change GO:0006265 12 8 1,000 1,699E-05 5,11E-03 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 1,699E-05 4,542E-03 ! chromosome segregation GO:0007059 113 67 2,000 2,06E-05 4,956E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 2,183E-05 4,776E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 2,183E-05 4,378E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 2,728E-05 5,049E-03 ! regulation of stress fiber formation GO:0051492 30 10 1,000 2,728E-05 4,688E-03 ! DNA ligation GO:0006266 19 10 1,000 2,728E-05 4,376E-03 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 2,728E-05 4,102E-03 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 2,728E-05 3,861E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 3,333E-05 4,455E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 3,997E-05 5,062E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 4,722E-05 5,68E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 5,506E-05 6,308E-03 ! regulation of mRNA processing GO:0050684 24 14 1,000 5,506E-05 6,022E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 5,506E-05 5,76E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 5,506E-05 5,52E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 5,865E-05 5,644E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 6,35E-05 5,876E-03 ! cardiac muscle contraction GO:0060048 26 15 1,000 6,35E-05 5,659E-03 ! mRNA splice site selection GO:0006376 38 15 1,000 6,35E-05 5,456E-03 ! interphase GO:0051325 213 98 2,000 6,434E-05 5,338E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 7,254E-05 5,817E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 7,254E-05 5,63E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 8,217E-05 6,178E-03 ! regulation of viral genome replication GO:0045069 28 17 1,000 8,217E-05 5,991E-03 ! skin development GO:0043588 36 19 1,000 1,032E-04 7,304E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,032E-04 7,095E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! heart process GO:0003015 30 19 1,000 1,032E-04 6,898E-03 GO:0060047|heart contraction, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,146E-04 7,454E-03 ! negative regulation of translation GO:0017148 29 20 1,000 1,146E-04 7,258E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 1,266E-04 7,812E-03 ! apoptotic nuclear changes GO:0030262 32 22 1,000 1,392E-04 8,374E-03 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,524E-04 8,944E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 1,524E-04 8,731E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of viral reproduction GO:0050792 38 23 1,000 1,524E-04 8,528E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 1,805E-04 9,873E-03 ! chromosome condensation GO:0030261 45 25 1,000 1,805E-04 9,653E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,805E-04 9,443E-03 ! fat cell differentiation GO:0045444 50 27 1,000 2,11E-04 0,01080309 ! negative regulation of protein modification process GO:0031400 60 28 1,000 2,272E-04 0,01138618 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,272E-04 0,01115381 ! spliceosome assembly GO:0000245 67 32 1,000 2,975E-04 0,01431508 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 3,563E-04 0,01681105 ! RNA export from nucleus GO:0006405 56 37 1,000 3,985E-04 0,01843726 ! nucleus organization GO:0006997 67 38 1,000 4,204E-04 0,01908507 ! keratinocyte differentiation GO:0030216 62 41 1,000 4,897E-04 0,02181728 ! striated muscle contraction GO:0006941 77 43 1,000 5,387E-04 0,02356584 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 5,9E-04 0,02535027 ! epidermal cell differentiation GO:0009913 68 46 1,000 6,166E-04 0,02602494 ! response to insulin stimulus GO:0032868 95 46 1,000 6,166E-04 0,02557623 ! response to calcium ion GO:0051592 81 47 1,000 6,436E-04 0,02624742 ! positive regulation of cell cycle GO:0045787 89 48 1,000 6,713E-04 0,02691904 ! ribonucleoprotein complex assembly GO:0022618 95 49 1,000 6,995E-04 0,02759104 ! positive regulation of growth GO:0045927 90 52 1,000 7,876E-04 0,0305639 ! response to UV GO:0009411 104 53 1,000 8,181E-04 0,03124312 ! nuclear export GO:0051168 97 55 1,000 8,808E-04 0,03311082 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 1,047E-03 0,03876392 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 1,082E-03 0,03945152 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 1,304E-03 0,04681705 ! negative regulation of kinase activity GO:0033673 131 68 1,000 1,343E-03 0,04750331 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 1,343E-03 0,04681485 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 1,382E-03 0,04750048 ! regulation of caspase activity GO:0043281 122 72 1,000 1,503E-03 0,0509492 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,503E-03 0,05024157 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 1,503E-03 0,04955333 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 1,503E-03 0,04888369 ! negative regulation of transferase activity GO:0051348 140 72 1,000 1,503E-03 0,04823191 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 1,587E-03 0,05024858 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 1,587E-03 0,049596 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 1,63E-03 0,0502771 ! regulation of actin filament-based process GO:0032970 152 77 1,000 1,717E-03 0,05229101 ! positive regulation of ligase activity GO:0051351 124 77 1,000 1,717E-03 0,05163738 ! regulation of peptidase activity GO:0052547 134 79 1,000 1,806E-03 0,05364936 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 1,806E-03 0,0529951 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 1,806E-03 0,05235661 ! response to metal ion GO:0010038 140 80 1,000 1,852E-03 0,05303404 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 1,898E-03 0,05371085 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of ligase activity GO:0051340 142 84 1,000 2,039E-03 0,05703376 ! response to unfolded protein GO:0006986 131 85 1,000 2,087E-03 0,05770868 ! response to inorganic substance GO:0010035 153 86 1,000 2,135E-03 0,05838294 ! mitochondrion organization GO:0007005 148 86 1,000 2,135E-03 0,05772695 ! positive regulation of protein modification process GO:0031401 136 88 1,000 2,234E-03 0,0597295 ! regulation of cell adhesion GO:0030155 212 89 1,000 2,285E-03 0,06040179 ! response to protein stimulus GO:0051789 149 91 1,000 2,387E-03 0,06241556 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 2,491E-03 0,06444109 GO:0010498|proteasomal protein catabolic process, ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 2,597E-03 0,06647784 ! cell cycle arrest GO:0007050 213 100 1,000 2,872E-03 0,07274628 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 3,978E-03 0,09970813 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 3,978E-03 0,09868021 ! positive regulation of helicase activity GO:0051096 11 5 0,000 3,978E-03 0,09767327 ! neuron fate determination GO:0048664 7 5 0,000 3,978E-03 0,09668667 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,978E-03 0,0957198 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 3,978E-03 0,09477208 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 3,978E-03 0,09384294 ! polyol transport GO:0015791 12 5 0,000 3,978E-03 0,09293185 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 3,978E-03 0,09203827 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 3,978E-03 0,09116171 ! response to superoxide GO:0000303 10 5 0,000 3,978E-03 0,0903017 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,978E-03 0,08945776 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 3,978E-03 0,08862944 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 3,978E-03 0,08781633 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 3,978E-03 0,087018 ! female meiosis GO:0007143 7 5 0,000 3,978E-03 0,08623405 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,978E-03 0,08546411 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 3,978E-03 0,08470779 ! cobalt ion transport GO:0006824 11 5 0,000 3,978E-03 0,08396474 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 3,978E-03 0,08323461 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 3,978E-03 0,08251707 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 3,978E-03 0,0818118 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 3,978E-03 0,08111848 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 3,978E-03 0,08043681 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 3,978E-03 0,0797665 ! embryonic camera-type eye development GO:0031076 10 5 0,000 3,978E-03 0,07910727 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 3,978E-03 0,07845885 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 3,978E-03 0,07782098 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 3,978E-03 0,07719339 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,978E-03 0,07657584 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,978E-03 0,0759681 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,978E-03 0,07536992 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 3,978E-03 0,07478109 ! negative chemotaxis GO:0050919 14 5 0,000 3,978E-03 0,0742014 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,978E-03 0,07363062 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 3,978E-03 0,07306855 ! sensory perception of bitter taste GO:0050913 7 5 0,000 3,978E-03 0,072515 ! behavioral response to pain GO:0048266 9 5 0,000 3,978E-03 0,07196977 ! clathrin coat assembly GO:0048268 14 5 0,000 3,978E-03 0,07143269 ! Notch receptor processing GO:0007220 8 5 0,000 3,978E-03 0,07090356 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,978E-03 0,07038221 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,978E-03 0,06986847 ! micturition GO:0060073 9 5 0,000 3,978E-03 0,06936217 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 3,978E-03 0,06886317 ! copulation GO:0007620 9 5 0,000 3,978E-03 0,06837129 ! glial cell fate commitment GO:0021781 13 5 0,000 3,978E-03 0,06788638 ! protein maturation by protein folding GO:0022417 13 5 0,000 3,978E-03 0,06740831 ! spermidine metabolic process GO:0008216 7 5 0,000 3,978E-03 0,06693692 ! regulation of potassium ion transport GO:0043266 10 5 0,000 3,978E-03 0,06647208 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 3,978E-03 0,06601366 ! apoptotic cell clearance GO:0043277 20 5 0,000 3,978E-03 0,06556151 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 3,978E-03 0,06511551 ! lipoprotein particle clearance GO:0034381 10 5 0,000 3,978E-03 0,06467554 ! grooming behavior GO:0007625 6 5 0,000 3,978E-03 0,06424148 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 3,978E-03 0,0638132 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 3,978E-03 0,0633906 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,978E-03 0,06297355 ! response to protozoan GO:0001562 10 5 0,000 3,978E-03 0,06256196 ! positive regulation of glycolysis GO:0045821 14 5 0,000 3,978E-03 0,06215571 ! lymph vessel development GO:0001945 10 5 0,000 3,978E-03 0,06175471 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 3,978E-03 0,06135885 ! endochondral ossification GO:0001958 16 5 0,000 3,978E-03 0,06096803 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 3,978E-03 0,06058215 ! parathyroid gland development GO:0060017 13 5 0,000 3,978E-03 0,06020113 ! anagen GO:0042640 6 5 0,000 3,978E-03 0,05982488 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 3,978E-03 0,05945329 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 3,978E-03 0,0590863 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 3,978E-03 0,0587238 ! dorsal spinal cord development GO:0021516 7 5 0,000 3,978E-03 0,05836573 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 3,978E-03 0,058012 ! sphingoid catabolic process GO:0046521 6 5 0,000 3,978E-03 0,05766253 ! skeletal myofibril assembly GO:0014866 10 5 0,000 3,978E-03 0,05731725 ! smooth muscle tissue development GO:0048745 28 5 0,000 3,978E-03 0,05697607 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 3,978E-03 0,05663894 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 3,978E-03 0,05630577 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 3,978E-03 0,05597649 ! cardiac muscle fiber development GO:0048739 10 5 0,000 3,978E-03 0,05565105 ! transepithelial chloride transport GO:0030321 9 5 0,000 3,978E-03 0,05532936 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 3,978E-03 0,05501138 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 3,978E-03 0,05469703 ! neutrophil mediated immunity GO:0002446 7 5 0,000 3,978E-03 0,05438625 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 3,978E-03 0,05407898 ! histidine catabolic process GO:0006548 6 5 0,000 3,978E-03 0,05377517 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 3,978E-03 0,05347475 ! microvillus organization GO:0032528 7 5 0,000 3,978E-03 0,05317767 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 3,978E-03 0,05288387 ! L-serine biosynthetic process GO:0006564 6 5 0,000 3,978E-03 0,0525933 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,978E-03 0,0523059 ! tryptophan metabolic process GO:0006568 9 5 0,000 3,978E-03 0,05202163 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 3,978E-03 0,05174043 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,978E-03 0,05146226 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 3,978E-03 0,05118706 ! polyol catabolic process GO:0046174 7 5 0,000 3,978E-03 0,05091479 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 3,978E-03 0,0506454 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,978E-03 0,05037884 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,978E-03 0,05011508 ! muscle cell migration GO:0014812 8 5 0,000 3,978E-03 0,04985406 ! mitochondrial fission GO:0000266 8 5 0,000 3,978E-03 0,04959575 ! sister chromatid cohesion GO:0007062 12 5 0,000 3,978E-03 0,0493401 ! mRNA transcription GO:0009299 9 5 0,000 3,978E-03 0,04908708 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 3,978E-03 0,04883663 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 3,978E-03 0,04858873 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 3,978E-03 0,04834333 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,978E-03 0,0481004 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 3,978E-03 0,0478599 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 3,978E-03 0,04762179 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 3,978E-03 0,04738604 ! response to food GO:0032094 6 5 0,000 3,978E-03 0,04715261 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 3,978E-03 0,04692147 ! positive regulation of transporter activity GO:0032411 8 5 0,000 3,978E-03 0,04669259 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 3,978E-03 0,04646592 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,978E-03 0,04624145 ! paraxial mesoderm development GO:0048339 14 5 0,000 3,978E-03 0,04601913 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 3,978E-03 0,04579895 ! forebrain neuron development GO:0021884 13 5 0,000 3,978E-03 0,04558086 ! lipoprotein catabolic process GO:0042159 11 5 0,000 3,978E-03 0,04536483 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 3,978E-03 0,04515085 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 3,978E-03 0,04493887 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,978E-03 0,04472888 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 3,978E-03 0,04452084 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 3,978E-03 0,04431472 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,978E-03 0,04411051 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 3,978E-03 0,04390817 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 3,978E-03 0,04370767 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,978E-03 0,043509 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 3,978E-03 0,04331213 ! basic amino acid transport GO:0015802 11 5 0,000 3,978E-03 0,04311703 ! cellular glucose homeostasis GO:0001678 5 5 0,000 3,978E-03 0,04292368 ! early endosome to late endosome transport GO:0045022 12 5 0,000 3,978E-03 0,04273205 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,978E-03 0,04254213 ! depyrimidination GO:0045008 10 5 0,000 3,978E-03 0,04235389 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 3,978E-03 0,04216731 ! regulation of centrosome cycle GO:0046605 7 5 0,000 3,978E-03 0,04198237 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 3,978E-03 0,04179904 ! zinc ion homeostasis GO:0055069 8 5 0,000 3,978E-03 0,0416173 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 3,978E-03 0,04143714 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 3,978E-03 0,04125853 ! forebrain morphogenesis GO:0048853 13 5 0,000 3,978E-03 0,04108146 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 3,978E-03 0,0409059 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 3,978E-03 0,04073183 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 3,978E-03 0,04055924 ! peptidyl-arginine modification GO:0018195 9 5 0,000 3,978E-03 0,0403881 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 3,978E-03 0,0402184 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,978E-03 0,04005013 ! response to arsenic GO:0046685 10 5 0,000 3,978E-03 0,03988325 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 3,978E-03 0,03971776 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 3,978E-03 0,03955364 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 3,978E-03 0,03939086 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 3,978E-03 0,03922943 ! response to cadmium ion GO:0046686 7 5 0,000 3,978E-03 0,03906931 ! bile acid biosynthetic process GO:0006699 6 5 0,000 3,978E-03 0,03891049 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 3,978E-03 0,03875296 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 3,978E-03 0,03859669 ! decidualization GO:0046697 11 5 0,000 3,978E-03 0,03844169 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 3,978E-03 0,03828792 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 3,978E-03 0,03813538 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,978E-03 0,03798405 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,978E-03 0,03783391 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 3,978E-03 0,03768496 ! base conversion or substitution editing GO:0016553 5 5 0,000 3,978E-03 0,03753718 ! neural tube patterning GO:0021532 7 5 0,000 3,978E-03 0,03739055 ! embryonic cleavage GO:0040016 6 5 0,000 3,978E-03 0,03724506 ! peroxisome fission GO:0016559 5 5 0,000 3,978E-03 0,0371007 ! histone demethylation GO:0016577 10 5 0,000 3,978E-03 0,03695745 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 3,978E-03 0,03681531 ! mitotic recombination GO:0006312 9 5 0,000 3,978E-03 0,03667425 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 3,978E-03 0,03653428 ! metaphase plate congression GO:0051310 7 5 0,000 3,978E-03 0,03639536 ! regulation of sterol transport GO:0032371 7 5 0,000 3,978E-03 0,0362575 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 3,978E-03 0,03612068 ! enteric nervous system development GO:0048484 8 5 0,000 3,978E-03 0,03598489 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 3,978E-03 0,03585011 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 3,978E-03 0,03571634 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 3,978E-03 0,03558357 ! muscle cell proliferation GO:0033002 11 5 0,000 3,978E-03 0,03545178 ! skeletal muscle regeneration GO:0043403 8 5 0,000 3,978E-03 0,03532096 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 3,978E-03 0,0351911 ! plasminogen activation GO:0031639 5 5 0,000 3,978E-03 0,0350622 ! B cell homeostasis GO:0001782 13 5 0,000 3,978E-03 0,03493423 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 3,978E-03 0,0348072 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 3,978E-03 0,03468109 ! metaphase GO:0051323 8 5 0,000 3,978E-03 0,03455588 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 3,978E-03 0,03443158 ! cellular response to nutrient GO:0031670 8 5 0,000 3,978E-03 0,03430817 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 3,978E-03 0,03418564 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,978E-03 0,03406399 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,978E-03 0,03394319 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 3,978E-03 0,03382325 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 3,978E-03 0,03370416 ! response to redox state GO:0051775 5 5 0,000 3,978E-03 0,03358589 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 3,978E-03 0,03346846 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 3,978E-03 0,03335185 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 3,978E-03 0,03323604 ! regulation of telomerase activity GO:0051972 6 5 0,000 3,978E-03 0,03312104 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,978E-03 0,03300683 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 3,978E-03 0,0328934 ! porphyrin catabolic process GO:0006787 12 5 0,000 3,978E-03 0,03278075 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 3,978E-03 0,03266887 ! striatum development GO:0021756 9 5 0,000 3,978E-03 0,03255776 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 3,978E-03 0,03244739 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 3,978E-03 0,03233777 ! glial cell migration GO:0008347 11 5 0,000 3,978E-03 0,03222889 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 3,978E-03 0,03212074 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 3,978E-03 0,03201331 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,978E-03 0,0319066 ! somatic stem cell maintenance GO:0035019 15 5 0,000 3,978E-03 0,0318006 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 3,978E-03 0,0316953 ! negative regulation of lipase activity GO:0060192 8 5 0,000 3,978E-03 0,03159069 ! neuroprotection GO:0043526 6 5 0,000 3,978E-03 0,03148678 ! neural plate development GO:0001840 8 5 0,000 3,978E-03 0,03138354 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 3,978E-03 0,03128098 ! regulation of sensory perception GO:0051931 7 5 0,000 3,978E-03 0,03117909 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 3,978E-03 0,03107786 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 3,978E-03 0,03097728 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 3,978E-03 0,03087736 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 3,978E-03 0,03077807 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 3,978E-03 0,03067942 ! sequestering of calcium ion GO:0051208 7 5 0,000 3,978E-03 0,03058141 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,978E-03 0,03048401 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 3,978E-03 0,03038724 ! spindle assembly GO:0051225 6 5 0,000 3,978E-03 0,03029108 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 3,978E-03 0,03019552 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 3,978E-03 0,03010057 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 3,978E-03 0,03000621 ! drug metabolic process GO:0017144 6 5 0,000 3,978E-03 0,02991244 ! stem cell division GO:0017145 11 5 0,000 3,978E-03 0,02981925 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 3,978E-03 0,02972665 ! organ regeneration GO:0031100 7 5 0,000 3,978E-03 0,02963461 ! carnitine metabolic process GO:0009437 7 5 0,000 3,978E-03 0,02954315 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 3,978E-03 0,02945225 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 3,978E-03 0,0293619 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 4,772E-03 0,03511312 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 4,772E-03 0,03500607 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 4,772E-03 0,03489967 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 4,772E-03 0,03479391 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 4,772E-03 0,0346888 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 4,772E-03 0,03458431 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 4,772E-03 0,03448046 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 4,772E-03 0,03437722 ! sleep GO:0030431 13 6 0,000 4,772E-03 0,0342746 ! response to oxygen radical GO:0000305 11 6 0,000 4,772E-03 0,03417259 ! positive regulation of axon extension GO:0045773 11 6 0,000 4,772E-03 0,03407119 ! myoblast cell fate commitment GO:0048625 16 6 0,000 4,772E-03 0,03397039 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 4,772E-03 0,03387018 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 4,772E-03 0,03377056 ! regulation of interferon-beta production GO:0032648 8 6 0,000 4,772E-03 0,03367153 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 4,772E-03 0,03357308 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 4,772E-03 0,03347519 ! forebrain regionalization GO:0021871 8 6 0,000 4,772E-03 0,03337788 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 4,772E-03 0,03328114 ! male meiosis GO:0007140 7 6 0,000 4,772E-03 0,03318495 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 4,772E-03 0,03308931 ! response to zinc ion GO:0010043 9 6 0,000 4,772E-03 0,03299423 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 4,772E-03 0,03289969 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 4,772E-03 0,03280569 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 4,772E-03 0,03271223 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 4,772E-03 0,03261929 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 4,772E-03 0,03252689 ! malate metabolic process GO:0006108 11 6 0,000 4,772E-03 0,032435 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 4,772E-03 0,03234364 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 4,772E-03 0,03225279 ! protein refolding GO:0042026 15 6 0,000 4,772E-03 0,03216244 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 4,772E-03 0,0320726 ! opsonization GO:0008228 8 6 0,000 4,772E-03 0,03198326 ! mating behavior GO:0007617 7 6 0,000 4,772E-03 0,03189442 ! neuron remodeling GO:0016322 15 6 0,000 4,772E-03 0,03180607 ! erythrocyte maturation GO:0043249 7 6 0,000 4,772E-03 0,03171821 ! embryonic hemopoiesis GO:0035162 14 6 0,000 4,772E-03 0,03163083 ! equilibrioception GO:0050957 14 6 0,000 4,772E-03 0,03154393 ! protein amino acid dealkylation GO:0008214 12 6 0,000 4,772E-03 0,03145751 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 4,772E-03 0,03137156 ! photoreceptor cell development GO:0042461 10 6 0,000 4,772E-03 0,03128608 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 4,772E-03 0,03120106 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 4,772E-03 0,03111651 ! response to interferon-gamma GO:0034341 15 6 0,000 4,772E-03 0,03103241 ! toxin metabolic process GO:0009404 11 6 0,000 4,772E-03 0,03094876 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 4,772E-03 0,03086557 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 4,772E-03 0,03078282 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 4,772E-03 0,03070051 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 4,772E-03 0,03061864 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 4,772E-03 0,03053721 ! cGMP-mediated signaling GO:0019934 13 6 0,000 4,772E-03 0,03045621 ! activation of MAPKKK activity GO:0000185 12 6 0,000 4,772E-03 0,03037564 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 4,772E-03 0,03029549 ! thymic T cell selection GO:0045061 12 6 0,000 4,772E-03 0,03021577 ! protein lipoylation GO:0009249 10 6 0,000 4,772E-03 0,03013646 ! cysteine metabolic process GO:0006534 10 6 0,000 4,772E-03 0,03005757 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 4,772E-03 0,02997909 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 4,772E-03 0,02990102 ! glutamate catabolic process GO:0006538 10 6 0,000 4,772E-03 0,02982336 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 4,772E-03 0,02974609 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 4,772E-03 0,02966923 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 4,772E-03 0,02959276 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 4,772E-03 0,02951669 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 4,772E-03 0,029441 ! hyperosmotic response GO:0006972 9 6 0,000 4,772E-03 0,02936571 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 4,772E-03 0,0292908 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 4,772E-03 0,02921626 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 4,772E-03 0,02914211 ! urea metabolic process GO:0019627 7 6 0,000 4,772E-03 0,02906833 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 4,772E-03 0,02899493 ! neutrophil activation GO:0042119 8 6 0,000 4,772E-03 0,02892189 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 4,772E-03 0,02884923 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 4,772E-03 0,02877692 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 4,772E-03 0,02870498 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 4,772E-03 0,0286334 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 4,772E-03 0,02856217 ! neuron apoptosis GO:0051402 9 6 0,000 4,772E-03 0,02849129 ! nucleoside salvage GO:0043174 9 6 0,000 4,772E-03 0,02842077 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 4,772E-03 0,0283506 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 4,772E-03 0,02828077 ! T cell mediated immunity GO:0002456 16 6 0,000 4,772E-03 0,02821128 ! negative regulation of platelet activation GO:0010544 9 6 0,000 4,772E-03 0,02814214 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 4,772E-03 0,02807333 ! carnitine transport GO:0015879 10 6 0,000 4,772E-03 0,02800486 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 4,772E-03 0,02793672 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,772E-03 0,02786891 ! positive regulation of exocytosis GO:0045921 8 6 0,000 4,772E-03 0,02780143 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 4,772E-03 0,02773428 ! 5S class rRNA transcription GO:0042791 11 6 0,000 4,772E-03 0,02766745 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 4,772E-03 0,02760094 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 4,772E-03 0,02753475 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 4,772E-03 0,02746888 ! sodium ion homeostasis GO:0055078 11 6 0,000 4,772E-03 0,02740332 ! establishment of spindle localization GO:0051293 12 6 0,000 4,772E-03 0,02733808 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 4,772E-03 0,02727314 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 4,772E-03 0,02720851 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 4,772E-03 0,02714419 ! neural nucleus development GO:0048857 14 6 0,000 4,772E-03 0,02708017 ! response to UV-C GO:0010225 11 6 0,000 4,772E-03 0,02701645 ! astrocyte development GO:0014002 15 6 0,000 4,772E-03 0,02695303 ! protein targeting to lysosome GO:0006622 10 6 0,000 4,772E-03 0,02688991 ! purine base biosynthetic process GO:0009113 17 6 0,000 4,772E-03 0,02682708 ! interaction with symbiont GO:0051702 13 6 0,000 4,772E-03 0,02676455 ! regulation of dendrite development GO:0050773 16 6 0,000 4,772E-03 0,02670231 ! skeletal muscle contraction GO:0003009 6 6 0,000 4,772E-03 0,02664035 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 4,772E-03 0,02657868 ! response to copper ion GO:0046688 10 6 0,000 4,772E-03 0,0265173 ! response to exogenous dsRNA GO:0043330 10 6 0,000 4,772E-03 0,0264562 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 4,772E-03 0,02639538 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,772E-03 0,02633484 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 4,772E-03 0,02627458 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 4,772E-03 0,02621459 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 4,772E-03 0,02615488 ! regulation of dopamine secretion GO:0014059 14 6 0,000 4,772E-03 0,02609544 ! nucleoside catabolic process GO:0009164 7 6 0,000 4,772E-03 0,02603626 ! hair follicle maturation GO:0048820 7 6 0,000 4,772E-03 0,02597736 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 4,772E-03 0,02591872 ! Schwann cell development GO:0014044 15 6 0,000 4,772E-03 0,02586034 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 4,772E-03 0,02580223 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 4,772E-03 0,02574438 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 4,772E-03 0,02568678 ! subpallium development GO:0021544 10 6 0,000 4,772E-03 0,02562945 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 4,772E-03 0,02557236 ! histone ubiquitination GO:0016574 8 6 0,000 4,772E-03 0,02551554 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 4,772E-03 0,02545896 ! maintenance of organ identity GO:0048496 9 6 0,000 4,772E-03 0,02540264 ! G2 phase GO:0051319 16 6 0,000 4,772E-03 0,02534656 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 4,772E-03 0,02529073 ! establishment of planar polarity GO:0001736 7 6 0,000 4,772E-03 0,02523515 ! regulation of mast cell activation GO:0033003 12 6 0,000 4,772E-03 0,02517981 ! membrane to membrane docking GO:0022614 14 6 0,000 4,772E-03 0,02512471 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 4,772E-03 0,02506985 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 4,772E-03 0,02501523 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 4,772E-03 0,02496085 ! receptor internalization GO:0031623 10 6 0,000 4,772E-03 0,02490671 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 4,772E-03 0,0248528 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 4,772E-03 0,02479912 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,772E-03 0,02474567 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 4,772E-03 0,02469246 ! protein deubiquitination GO:0016579 14 6 0,000 4,772E-03 0,02463947 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 4,772E-03 0,02458671 ! protein destabilization GO:0031648 9 6 0,000 4,772E-03 0,02453417 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 4,772E-03 0,02448186 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 4,772E-03 0,02442977 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 4,772E-03 0,0243779 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 4,772E-03 0,02432625 ! progesterone metabolic process GO:0042448 10 6 0,000 4,772E-03 0,02427482 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 4,772E-03 0,02422361 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 4,772E-03 0,02417261 ! negative regulation of axon extension GO:0030517 21 6 0,000 4,772E-03 0,02412183 ! removal of superoxide radicals GO:0019430 11 6 0,000 4,772E-03 0,02407126 ! triglyceride catabolic process GO:0019433 10 6 0,000 4,772E-03 0,0240209 ! determination of adult lifespan GO:0008340 15 6 0,000 4,772E-03 0,02397076 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 4,772E-03 0,02392082 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 4,772E-03 0,02387108 ! cerebellar cortex formation GO:0021697 8 6 0,000 4,772E-03 0,02382156 ! catecholamine transport GO:0051937 9 6 0,000 4,772E-03 0,02377224 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 4,772E-03 0,02372312 ! sensory cilium assembly GO:0035058 10 6 0,000 4,772E-03 0,02367421 ! organ or tissue specific immune response GO:0002251 7 6 0,000 4,772E-03 0,0236255 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 4,772E-03 0,02357699 ! maternal placenta development GO:0001893 12 6 0,000 4,772E-03 0,02352867 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 4,772E-03 0,02348056 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 4,772E-03 0,02343264 ! negative regulation of B cell activation GO:0050869 13 6 0,000 4,772E-03 0,02338491 ! protein amino acid prenylation GO:0018346 16 6 0,000 4,772E-03 0,02333738 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 4,772E-03 0,02329004 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 4,772E-03 0,0232429 ! positive regulation of coagulation GO:0050820 12 6 0,000 4,772E-03 0,02319594 ! tRNA transcription GO:0009304 14 7 0,000 5,565E-03 0,02699707 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 5,565E-03 0,02694275 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 5,565E-03 0,02688864 ! behavioral response to cocaine GO:0048148 14 7 0,000 5,565E-03 0,02683476 ! regulation of helicase activity GO:0051095 15 7 0,000 5,565E-03 0,02678109 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 5,565E-03 0,02672763 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 5,565E-03 0,02667439 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 5,565E-03 0,02662136 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 5,565E-03 0,02656854 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 5,565E-03 0,02651593 ! prostate gland development GO:0030850 13 7 0,000 5,565E-03 0,02646353 ! nucleotide-sugar transport GO:0015780 12 7 0,000 5,565E-03 0,02641133 ! synaptonemal complex assembly GO:0007130 10 7 0,000 5,565E-03 0,02635934 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 5,565E-03 0,02630755 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 5,565E-03 0,02625597 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 5,565E-03 0,02620459 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 5,565E-03 0,02615341 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 5,565E-03 0,02610243 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 5,565E-03 0,02605164 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 5,565E-03 0,02600106 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 5,565E-03 0,02595067 ! SMAD protein complex assembly GO:0007183 12 7 0,000 5,565E-03 0,02590047 ! glycolipid transport GO:0046836 10 7 0,000 5,565E-03 0,02585047 ! protein amino acid sulfation GO:0006477 10 7 0,000 5,565E-03 0,02580066 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 5,565E-03 0,02575105 ! neuron adhesion GO:0007158 12 7 0,000 5,565E-03 0,02570162 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 5,565E-03 0,02565238 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 5,565E-03 0,02560334 ! actin-myosin filament sliding GO:0033275 11 7 0,000 5,565E-03 0,02555447 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 5,565E-03 0,0255058 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 5,565E-03 0,02545731 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 5,565E-03 0,025409 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 5,565E-03 0,02536088 ! mRNA stabilization GO:0048255 18 7 0,000 5,565E-03 0,02531294 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 5,565E-03 0,02526518 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 5,565E-03 0,0252176 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 5,565E-03 0,0251702 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 5,565E-03 0,02512297 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 5,565E-03 0,02507593 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 5,565E-03 0,02502906 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 5,565E-03 0,02498236 ! lipoprotein transport GO:0042953 14 7 0,000 5,565E-03 0,02493584 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 5,565E-03 0,02488949 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 5,565E-03 0,02484331 ! rhythmic behavior GO:0007622 15 7 0,000 5,565E-03 0,0247973 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 5,565E-03 0,02475147 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 5,565E-03 0,0247058 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 5,565E-03 0,0246603 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 5,565E-03 0,02461497 ! regulation of odontogenesis GO:0042481 13 7 0,000 5,565E-03 0,02456981 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 5,565E-03 0,02452481 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 5,565E-03 0,02447997 ! mechanosensory behavior GO:0007638 14 7 0,000 5,565E-03 0,0244353 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 5,565E-03 0,02439079 ! positive regulation of isotype switching GO:0045830 15 7 0,000 5,565E-03 0,02434644 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 5,565E-03 0,02430226 ! protein-cofactor linkage GO:0018065 13 7 0,000 5,565E-03 0,02425823 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 5,565E-03 0,02421437 ! spinal cord patterning GO:0021511 13 7 0,000 5,565E-03 0,02417066 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 5,565E-03 0,02412711 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 5,565E-03 0,02408371 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 5,565E-03 0,02404047 ! adrenal gland development GO:0030325 17 7 0,000 5,565E-03 0,02399739 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 5,565E-03 0,02395446 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 5,565E-03 0,02391169 ! ovulation GO:0030728 9 7 0,000 5,565E-03 0,02386906 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 5,565E-03 0,02382659 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 5,565E-03 0,02378427 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 5,565E-03 0,0237421 ! microtubule nucleation GO:0007020 20 7 0,000 5,565E-03 0,02370008 ! proline biosynthetic process GO:0006561 10 7 0,000 5,565E-03 0,02365821 ! thyroid hormone generation GO:0006590 13 7 0,000 5,565E-03 0,02361648 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 5,565E-03 0,0235749 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 5,565E-03 0,02353347 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 5,565E-03 0,02349218 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 5,565E-03 0,02345104 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 5,565E-03 0,02341004 ! galactose metabolic process GO:0006012 13 7 0,000 5,565E-03 0,02336919 ! vesicle fusion GO:0006906 17 7 0,000 5,565E-03 0,02332847 ! response to dietary excess GO:0002021 8 7 0,000 5,565E-03 0,0232879 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 5,565E-03 0,02324747 ! intracellular pH reduction GO:0051452 11 7 0,000 5,565E-03 0,02320718 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 5,565E-03 0,02316703 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 5,565E-03 0,02312702 ! organ growth GO:0035265 15 7 0,000 5,565E-03 0,02308715 ! purine salvage GO:0043101 10 7 0,000 5,565E-03 0,02304741 ! nucleoside transport GO:0015858 8 7 0,000 5,565E-03 0,02300781 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 5,565E-03 0,02296834 ! parturition GO:0007567 14 7 0,000 5,565E-03 0,02292901 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 5,565E-03 0,02288982 ! rRNA modification GO:0000154 14 7 0,000 5,565E-03 0,02285076 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 5,565E-03 0,02281183 ! spindle checkpoint GO:0031577 15 7 0,000 5,565E-03 0,02277303 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 5,565E-03 0,02273437 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 5,565E-03 0,02269584 ! macrophage differentiation GO:0030225 11 7 0,000 5,565E-03 0,02265744 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 5,565E-03 0,02261916 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 5,565E-03 0,02258102 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 5,565E-03 0,022543 ! hyaluronan metabolic process GO:0030212 8 7 0,000 5,565E-03 0,02250512 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 5,565E-03 0,02246736 ! anterograde axon cargo transport GO:0008089 18 7 0,000 5,565E-03 0,02242972 ! fibrinolysis GO:0042730 10 7 0,000 5,565E-03 0,02239221 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 5,565E-03 0,02235483 ! eating behavior GO:0042755 7 7 0,000 5,565E-03 0,02231757 ! B cell lineage commitment GO:0002326 21 7 0,000 5,565E-03 0,02228044 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 5,565E-03 0,02224343 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 5,565E-03 0,02220654 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 5,565E-03 0,02216978 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 5,565E-03 0,02213313 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 5,565E-03 0,02209661 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 5,565E-03 0,02206021 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 5,565E-03 0,02202392 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 5,565E-03 0,02198776 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 5,565E-03 0,02195171 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 5,565E-03 0,02191578 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 5,565E-03 0,02187997 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 5,565E-03 0,02184428 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 5,565E-03 0,0218087 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 5,565E-03 0,02177324 ! regulation of meiosis GO:0040020 12 7 0,000 5,565E-03 0,0217379 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 5,565E-03 0,02170267 ! T cell lineage commitment GO:0002360 16 7 0,000 5,565E-03 0,02166755 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 5,565E-03 0,02163254 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 5,565E-03 0,02159765 ! oxygen homeostasis GO:0032364 12 7 0,000 5,565E-03 0,02156287 ! transcription termination GO:0006353 13 7 0,000 5,565E-03 0,02152821 ! response to tumor cell GO:0002347 13 7 0,000 5,565E-03 0,02149365 ! regulation of respiratory burst GO:0060263 11 7 0,000 5,565E-03 0,02145921 ! coenzyme A metabolic process GO:0015936 12 7 0,000 5,565E-03 0,02142487 ! anaphase GO:0051322 17 7 0,000 5,565E-03 0,02139065 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 5,565E-03 0,02135653 ! axonal fasciculation GO:0007413 18 7 0,000 5,565E-03 0,02132252 ! negative regulation of nuclear division GO:0051784 14 7 0,000 5,565E-03 0,02128862 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 5,565E-03 0,02125483 ! peptidyl-threonine modification GO:0018210 25 7 0,000 5,565E-03 0,02122115 ! diuresis GO:0030146 12 7 0,000 5,565E-03 0,02118757 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 5,565E-03 0,0211541 ! thiamin metabolic process GO:0006772 7 7 0,000 5,565E-03 0,02112073 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 5,565E-03 0,02108747 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 5,565E-03 0,02105432 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 5,565E-03 0,02102126 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 5,565E-03 0,02098831 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 5,565E-03 0,02095547 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 5,565E-03 0,02092273 ! melanin biosynthetic process GO:0042438 8 7 0,000 5,565E-03 0,02089009 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 5,565E-03 0,02085755 ! dopamine biosynthetic process GO:0042416 18 7 0,000 5,565E-03 0,02082511 ! glycolipid catabolic process GO:0019377 15 7 0,000 5,565E-03 0,02079277 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 5,565E-03 0,02076053 ! lymph node development GO:0048535 10 7 0,000 5,565E-03 0,0207284 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 5,565E-03 0,02069636 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 5,565E-03 0,02066442 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 5,565E-03 0,02063258 ! endosome to lysosome transport GO:0008333 11 7 0,000 5,565E-03 0,02060084 ! protein modification by small protein removal GO:0070646 16 7 0,000 5,565E-03 0,02056919 ! adult feeding behavior GO:0008343 9 7 0,000 5,565E-03 0,02053764 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 5,565E-03 0,02050619 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 5,565E-03 0,02047484 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 5,565E-03 0,02044358 ! muscle adaptation GO:0043500 14 7 0,000 5,565E-03 0,02041242 ! embryonic heart tube development GO:0035050 10 7 0,000 5,565E-03 0,02038135 ! retina homeostasis GO:0001895 12 7 0,000 5,565E-03 0,02035037 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 5,565E-03 0,02031949 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 5,565E-03 0,0202887 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 5,565E-03 0,02025801 ! protein prenylation GO:0018342 18 7 0,000 5,565E-03 0,02022741 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 5,565E-03 0,0201969 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 5,565E-03 0,02016648 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 5,565E-03 0,02013616 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 6,358E-03 0,02296943 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 6,358E-03 0,02293499 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 6,358E-03 0,02290066 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 6,358E-03 0,02286643 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 6,358E-03 0,0228323 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 6,358E-03 0,02279827 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 6,358E-03 0,02276434 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 6,358E-03 0,02273052 ! neutral lipid catabolic process GO:0046461 13 8 0,000 6,358E-03 0,02269679 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 6,358E-03 0,02266317 ! meiotic prophase I GO:0007128 13 8 0,000 6,358E-03 0,02262964 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 6,358E-03 0,02259622 ! oligopeptide transport GO:0006857 15 8 0,000 6,358E-03 0,02256289 ! UTP metabolic process GO:0046051 8 8 0,000 6,358E-03 0,02252966 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 6,358E-03 0,02249653 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 6,358E-03 0,02246349 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 6,358E-03 0,02243056 ! macrophage chemotaxis GO:0048246 12 8 0,000 6,358E-03 0,02239772 ! succinate metabolic process GO:0006105 14 8 0,000 6,358E-03 0,02236497 ! membrane hyperpolarization GO:0060081 10 8 0,000 6,358E-03 0,02233232 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 6,358E-03 0,02229977 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 6,358E-03 0,02226731 ! T-helper 1 type immune response GO:0042088 12 8 0,000 6,358E-03 0,02223494 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 6,358E-03 0,02220267 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 6,358E-03 0,02217049 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,358E-03 0,02213841 ! ganglioside metabolic process GO:0001573 19 8 0,000 6,358E-03 0,02210642 ! reflex GO:0060004 16 8 0,000 6,358E-03 0,02207452 ! negative regulation of endocytosis GO:0045806 11 8 0,000 6,358E-03 0,02204271 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 6,358E-03 0,02201099 ! endothelial cell differentiation GO:0045446 17 8 0,000 6,358E-03 0,02197937 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 6,358E-03 0,02194783 ! glycerolipid catabolic process GO:0046503 13 8 0,000 6,358E-03 0,02191639 ! hemoglobin metabolic process GO:0020027 13 8 0,000 6,358E-03 0,02188503 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 6,358E-03 0,02185377 ! pigment granule organization GO:0048753 16 8 0,000 6,358E-03 0,0218226 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 6,358E-03 0,02179151 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 6,358E-03 0,02176051 ! astrocyte differentiation GO:0048708 18 8 0,000 6,358E-03 0,0217296 ! histidine metabolic process GO:0006547 16 8 0,000 6,358E-03 0,02169878 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 6,358E-03 0,02166804 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 6,358E-03 0,0216374 ! glycine catabolic process GO:0006546 13 8 0,000 6,358E-03 0,02160684 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 6,358E-03 0,02157636 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 6,358E-03 0,02154597 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 6,358E-03 0,02151567 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 6,358E-03 0,02148545 ! regulation of pigmentation during development GO:0048070 24 8 0,000 6,358E-03 0,02145531 ! melanin metabolic process GO:0006582 15 8 0,000 6,358E-03 0,02142527 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 6,358E-03 0,0213953 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 6,358E-03 0,02136542 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 6,358E-03 0,02133562 ! macrophage activation GO:0042116 12 8 0,000 6,358E-03 0,0213059 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 6,358E-03 0,02127627 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 6,358E-03 0,02124672 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 6,358E-03 0,02121725 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 6,358E-03 0,02118787 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 6,358E-03 0,02115856 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 6,358E-03 0,02112934 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,358E-03 0,02110019 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 6,358E-03 0,02107113 ! osteoblast development GO:0002076 16 8 0,000 6,358E-03 0,02104214 ! positive regulation of vasodilation GO:0045909 13 8 0,000 6,358E-03 0,02101324 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 6,358E-03 0,02098442 ! negative regulation of translational initiation GO:0045947 10 8 0,000 6,358E-03 0,02095567 ! Schwann cell differentiation GO:0014037 19 8 0,000 6,358E-03 0,020927 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 6,358E-03 0,02089841 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 6,358E-03 0,0208699 ! response to UV-B GO:0010224 16 8 0,000 6,358E-03 0,02084147 ! protein targeting to vacuole GO:0006623 12 8 0,000 6,358E-03 0,02081311 ! protein retention in ER lumen GO:0006621 14 8 0,000 6,358E-03 0,02078484 ! intermediate filament organization GO:0045109 12 8 0,000 6,358E-03 0,02075663 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 6,358E-03 0,02072851 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 6,358E-03 0,02070046 ! cellular extravasation GO:0045123 12 8 0,000 6,358E-03 0,02067249 ! cardiac muscle cell development GO:0055013 13 8 0,000 6,358E-03 0,02064459 ! regulation of circadian rhythm GO:0042752 16 8 0,000 6,358E-03 0,02061676 ! response to antibiotic GO:0046677 11 8 0,000 6,358E-03 0,02058902 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 6,358E-03 0,02056134 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 6,358E-03 0,02053374 ! response to tropane GO:0014073 15 8 0,000 6,358E-03 0,02050622 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 6,358E-03 0,02047877 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 6,358E-03 0,02045139 ! melanosome transport GO:0032402 13 8 0,000 6,358E-03 0,02042408 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 6,358E-03 0,02039685 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 6,358E-03 0,02036969 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 6,358E-03 0,02034261 ! mast cell activation GO:0045576 14 8 0,000 6,358E-03 0,02031559 ! multicellular organismal aging GO:0010259 18 8 0,000 6,358E-03 0,02028865 ! dendrite morphogenesis GO:0048813 13 8 0,000 6,358E-03 0,02026177 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 6,358E-03 0,02023497 ! nucleosome disassembly GO:0006337 14 8 0,000 6,358E-03 0,02020824 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 6,358E-03 0,02018158 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 6,358E-03 0,02015499 ! leukocyte activation during immune response GO:0002366 13 8 0,000 6,358E-03 0,02012847 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 6,358E-03 0,02010202 ! establishment of chromosome localization GO:0051303 12 8 0,000 6,358E-03 0,02007564 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 6,358E-03 0,02004933 ! intracellular lipid transport GO:0032365 13 8 0,000 6,358E-03 0,02002309 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 6,358E-03 0,01999691 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 6,358E-03 0,01997081 ! regulation of macrophage activation GO:0043030 15 8 0,000 6,358E-03 0,01994477 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 6,358E-03 0,0199188 ! positive regulation of epidermis development GO:0045684 13 8 0,000 6,358E-03 0,0198929 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 6,358E-03 0,01986706 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 6,358E-03 0,0198413 ! hormone catabolic process GO:0042447 17 8 0,000 6,358E-03 0,0198156 ! positive regulation of glucose import GO:0046326 8 8 0,000 6,358E-03 0,01978996 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 6,358E-03 0,01976439 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 6,358E-03 0,01973889 ! ATP catabolic process GO:0006200 11 8 0,000 6,358E-03 0,01971345 ! blastocyst growth GO:0001832 19 8 0,000 6,358E-03 0,01968808 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 6,358E-03 0,01966278 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 6,358E-03 0,01963753 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 6,358E-03 0,01961236 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 6,358E-03 0,01958725 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 6,358E-03 0,0195622 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 6,358E-03 0,01953722 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 6,358E-03 0,0195123 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 6,358E-03 0,01948744 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 6,358E-03 0,01946265 ! amino sugar catabolic process GO:0046348 10 8 0,000 6,358E-03 0,01943792 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 6,358E-03 0,01941325 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 6,358E-03 0,01938864 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 6,358E-03 0,0193641 ! behavioral response to nicotine GO:0035095 12 8 0,000 6,358E-03 0,01933962 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 6,358E-03 0,0193152 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 6,358E-03 0,01929084 ! NAD biosynthetic process GO:0009435 13 8 0,000 6,358E-03 0,01926655 ! regulation of developmental growth GO:0048638 15 9 0,000 7,15E-03 0,02163934 ! axon extension GO:0048675 15 9 0,000 7,15E-03 0,02161216 ! autophagic vacuole formation GO:0000045 15 9 0,000 7,15E-03 0,02158504 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 7,15E-03 0,02155799 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 7,15E-03 0,02153101 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 7,15E-03 0,0215041 ! pentose-phosphate shunt GO:0006098 16 9 0,000 7,15E-03 0,02147725 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 7,15E-03 0,02145047 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 7,15E-03 0,02142376 ! cell proliferation in forebrain GO:0021846 15 9 0,000 7,15E-03 0,02139711 ! phosphate transport GO:0006817 19 9 0,000 7,15E-03 0,02137053 ! reproductive behavior GO:0019098 19 9 0,000 7,15E-03 0,02134402 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 7,15E-03 0,02131757 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 7,15E-03 0,02129118 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 7,15E-03 0,02126487 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 7,15E-03 0,02123861 ! GTP metabolic process GO:0046039 9 9 0,000 7,15E-03 0,02121243 ! RNA methylation GO:0001510 15 9 0,000 7,15E-03 0,0211863 ! elastic fiber assembly GO:0048251 15 9 0,000 7,15E-03 0,02116024 ! induction of positive chemotaxis GO:0050930 15 9 0,000 7,15E-03 0,02113425 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 7,15E-03 0,02110832 ! artery development GO:0060840 24 9 0,000 7,15E-03 0,02108245 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 7,15E-03 0,02105664 ! regulation of glycolysis GO:0006110 21 9 0,000 7,15E-03 0,0210309 ! cerebral cortex cell migration GO:0021795 15 9 0,000 7,15E-03 0,02100522 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 7,15E-03 0,02097961 ! chemosensory behavior GO:0007635 20 9 0,000 7,15E-03 0,02095405 ! microtubule bundle formation GO:0001578 21 9 0,000 7,15E-03 0,02092856 ! middle ear morphogenesis GO:0042474 14 9 0,000 7,15E-03 0,02090313 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 7,15E-03 0,02087776 ! leukocyte degranulation GO:0043299 16 9 0,000 7,15E-03 0,02085246 ! bile acid and bile salt transport GO:0015721 13 9 0,000 7,15E-03 0,02082721 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 7,15E-03 0,02080203 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 7,15E-03 0,02077691 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 7,15E-03 0,02075184 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 7,15E-03 0,02072684 ! protein targeting to ER GO:0045047 22 9 0,000 7,15E-03 0,0207019 ! ceramide biosynthetic process GO:0046513 19 9 0,000 7,15E-03 0,02067702 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 7,15E-03 0,02065219 ! T cell selection GO:0045058 23 9 0,000 7,15E-03 0,02062743 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 7,15E-03 0,02060273 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 7,15E-03 0,02057808 ! phosphagen metabolic process GO:0006599 12 9 0,000 7,15E-03 0,0205535 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 7,15E-03 0,02052897 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 7,15E-03 0,0205045 ! regulation of type I interferon production GO:0032479 12 9 0,000 7,15E-03 0,02048009 ! mannose metabolic process GO:0006013 13 9 0,000 7,15E-03 0,02045574 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 7,15E-03 0,02043145 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 7,15E-03 0,02040721 ! Rac protein signal transduction GO:0016601 17 9 0,000 7,15E-03 0,02038303 ! receptor clustering GO:0043113 18 9 0,000 7,15E-03 0,02035891 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 7,15E-03 0,02033484 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 7,15E-03 0,02031084 ! ruffle organization GO:0031529 15 9 0,000 7,15E-03 0,02028688 ! retinol metabolic process GO:0042572 18 9 0,000 7,15E-03 0,02026299 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 7,15E-03 0,02023915 ! behavioral fear response GO:0001662 22 9 0,000 7,15E-03 0,02021537 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 7,15E-03 0,02019164 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 7,15E-03 0,02016797 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 7,15E-03 0,02014435 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 7,15E-03 0,02012079 ! protein heterooligomerization GO:0051291 16 9 0,000 7,15E-03 0,02009729 ! oligodendrocyte development GO:0014003 10 9 0,000 7,15E-03 0,02007384 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 7,15E-03 0,02005044 ! segment specification GO:0007379 13 9 0,000 7,15E-03 0,0200271 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 7,15E-03 0,02000381 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 7,15E-03 0,01998058 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 7,15E-03 0,0199574 ! response to amine stimulus GO:0014075 13 9 0,000 7,15E-03 0,01993427 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 7,15E-03 0,0199112 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 7,15E-03 0,01988818 ! erythrocyte development GO:0048821 15 9 0,000 7,15E-03 0,01986522 ! gas homeostasis GO:0033483 16 9 0,000 7,15E-03 0,0198423 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 7,15E-03 0,01981944 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 7,15E-03 0,01979664 ! renal water homeostasis GO:0003091 14 9 0,000 7,15E-03 0,01977388 ! postreplication repair GO:0006301 22 9 0,000 7,15E-03 0,01975118 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 7,15E-03 0,01972853 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 7,15E-03 0,01970593 ! icosanoid secretion GO:0032309 15 9 0,000 7,15E-03 0,01968338 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 7,15E-03 0,01966089 ! cerebellum morphogenesis GO:0021587 14 9 0,000 7,15E-03 0,01963844 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 7,15E-03 0,01961605 ! regulation of cell division GO:0051302 15 9 0,000 7,15E-03 0,01959371 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 7,15E-03 0,01957142 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 7,15E-03 0,01954918 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 7,15E-03 0,01952699 ! sterol catabolic process GO:0016127 11 9 0,000 7,15E-03 0,01950485 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 7,15E-03 0,01948276 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 7,15E-03 0,01946072 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 7,15E-03 0,01943873 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 7,15E-03 0,01941679 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 7,15E-03 0,0193949 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 7,15E-03 0,01937306 ! musculoskeletal movement GO:0050881 14 9 0,000 7,15E-03 0,01935127 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 7,15E-03 0,01932953 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 7,15E-03 0,01930783 ! regulation of synaptogenesis GO:0051963 15 9 0,000 7,15E-03 0,01928619 ! purine base metabolic process GO:0006144 21 9 0,000 7,15E-03 0,01926459 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 7,15E-03 0,01924304 ! pigment granule transport GO:0051904 17 9 0,000 7,15E-03 0,01922154 ! regulation of fibrinolysis GO:0051917 16 9 0,000 7,15E-03 0,01920009 ! regulation of telomere maintenance GO:0032204 14 9 0,000 7,15E-03 0,01917868 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 7,15E-03 0,01915732 ! regulation of muscle adaptation GO:0043502 14 9 0,000 7,15E-03 0,01913601 ! regulation of amino acid transport GO:0051955 11 9 0,000 7,15E-03 0,01911475 ! mitochondrion localization GO:0051646 15 9 0,000 7,15E-03 0,01909354 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 7,942E-03 0,02118344 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 7,942E-03 0,02115998 ! negative regulation of blood pressure GO:0045776 26 10 0,000 7,942E-03 0,02113657 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 7,942E-03 0,02111322 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 7,942E-03 0,02108991 ! synapsis GO:0007129 13 10 0,000 7,942E-03 0,02106666 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 7,942E-03 0,02104346 ! N-glycan processing GO:0006491 20 10 0,000 7,942E-03 0,02102031 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 7,942E-03 0,02099721 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 7,942E-03 0,02097416 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 7,942E-03 0,02095116 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 7,942E-03 0,02092821 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 7,942E-03 0,02090532 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 7,942E-03 0,02088247 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 7,942E-03 0,02085967 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 7,942E-03 0,02083692 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 7,942E-03 0,02081423 ! androgen metabolic process GO:0008209 17 10 0,000 7,942E-03 0,02079158 ! phospholipid efflux GO:0033700 16 10 0,000 7,942E-03 0,02076898 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 7,942E-03 0,02074643 ! positive regulation of heart contraction GO:0045823 16 10 0,000 7,942E-03 0,02072393 ! lung alveolus development GO:0048286 26 10 0,000 7,942E-03 0,02070147 ! pathogenesis GO:0009405 13 10 0,000 7,942E-03 0,02067907 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 7,942E-03 0,02065671 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 7,942E-03 0,02063441 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 7,942E-03 0,02061215 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 7,942E-03 0,02058994 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 7,942E-03 0,02056777 ! endoderm development GO:0007492 16 10 0,000 7,942E-03 0,02054566 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 7,942E-03 0,02052359 ! arginine catabolic process GO:0006527 13 10 0,000 7,942E-03 0,02050157 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 7,942E-03 0,02047959 ! proline metabolic process GO:0006560 13 10 0,000 7,942E-03 0,02045767 ! glucan biosynthetic process GO:0009250 14 10 0,000 7,942E-03 0,02043579 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 7,942E-03 0,02041395 ! polyamine biosynthetic process GO:0006596 12 10 0,000 7,942E-03 0,02039217 ! V(D)J recombination GO:0033151 28 10 0,000 7,942E-03 0,02037043 ! reverse cholesterol transport GO:0043691 16 10 0,000 7,942E-03 0,02034873 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 7,942E-03 0,02032708 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 7,942E-03 0,02030548 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 7,942E-03 0,02028393 ! regulation of sodium ion transport GO:0002028 21 10 0,000 7,942E-03 0,02026242 ! multicellular organism growth GO:0035264 18 10 0,000 7,942E-03 0,02024095 ! phagocytosis, engulfment GO:0006911 28 10 0,000 7,942E-03 0,02021953 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 7,942E-03 0,02019816 ! epithelial cell development GO:0002064 20 10 0,000 7,942E-03 0,02017683 ! lens development in camera-type eye GO:0002088 16 10 0,000 7,942E-03 0,02015555 ! retinoic acid metabolic process GO:0042573 14 10 0,000 7,942E-03 0,02013431 ! macroautophagy GO:0016236 17 10 0,000 7,942E-03 0,02011312 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 7,942E-03 0,02009197 ! positive regulation of translational initiation GO:0045948 11 10 0,000 7,942E-03 0,02007086 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 7,942E-03 0,0200498 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 7,942E-03 0,02002878 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 7,942E-03 0,02000781 ! copper ion homeostasis GO:0055070 13 10 0,000 7,942E-03 0,01998688 ! regulation of bone resorption GO:0045124 25 10 0,000 7,942E-03 0,019966 ! regulation of gliogenesis GO:0014013 23 10 0,000 7,942E-03 0,01994516 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 7,942E-03 0,01992436 ! alpha-beta T cell activation GO:0046631 23 10 0,000 7,942E-03 0,0199036 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 7,942E-03 0,01988289 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 7,942E-03 0,01986222 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 7,942E-03 0,0198416 ! blastoderm segmentation GO:0007350 18 10 0,000 7,942E-03 0,01982102 ! response to dsRNA GO:0043331 20 10 0,000 7,942E-03 0,01980048 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 7,942E-03 0,01977998 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 7,942E-03 0,01975952 ! melanosome localization GO:0032400 16 10 0,000 7,942E-03 0,01973911 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 7,942E-03 0,01971874 ! regulation of B cell differentiation GO:0045577 19 10 0,000 7,942E-03 0,01969841 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 7,942E-03 0,01967813 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 7,942E-03 0,01965788 ! mRNA cleavage GO:0006379 17 10 0,000 7,942E-03 0,01963768 ! protein sumoylation GO:0016925 15 10 0,000 7,942E-03 0,01961752 ! hindbrain morphogenesis GO:0021575 19 10 0,000 7,942E-03 0,01959739 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 7,942E-03 0,01957732 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 7,942E-03 0,01955728 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 7,942E-03 0,01953728 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 7,942E-03 0,01951732 ! salivary gland development GO:0007431 27 10 0,000 7,942E-03 0,01949741 ! prophase GO:0051324 15 10 0,000 7,942E-03 0,01947753 ! negative regulation of neurological system process GO:0031645 19 10 0,000 7,942E-03 0,0194577 ! apical protein localization GO:0045176 15 10 0,000 7,942E-03 0,0194379 ! ubiquinone metabolic process GO:0006743 15 10 0,000 7,942E-03 0,01941815 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 7,942E-03 0,01939844 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 7,942E-03 0,01937876 ! midbrain development GO:0030901 13 10 0,000 7,942E-03 0,01935913 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 7,942E-03 0,01933953 ! methionine biosynthetic process GO:0009086 19 10 0,000 7,942E-03 0,01931998 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 7,942E-03 0,01930046 ! quaternary ammonium group transport GO:0015697 21 10 0,000 7,942E-03 0,01928099 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 7,942E-03 0,01926155 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 7,942E-03 0,01924215 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 7,942E-03 0,0192228 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 7,942E-03 0,01920348 ! oocyte development GO:0048599 17 10 0,000 7,942E-03 0,0191842 ! establishment of pigment granule localization GO:0051905 18 10 0,000 7,942E-03 0,01916495 ! blastocyst formation GO:0001825 17 10 0,000 7,942E-03 0,01914575 ! cerebellar cortex development GO:0021695 15 10 0,000 7,942E-03 0,01912659 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 7,942E-03 0,01910746 ! activation of innate immune response GO:0002218 12 10 0,000 7,942E-03 0,01908837 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 7,942E-03 0,01906932 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 7,942E-03 0,01905031 ! response to nicotine GO:0035094 20 10 0,000 7,942E-03 0,01903133 ! establishment of cell polarity GO:0030010 16 10 0,000 7,942E-03 0,0190124 ! negative regulation of immune effector process GO:0002698 20 10 0,000 7,942E-03 0,0189935 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 7,942E-03 0,01897464 ! localization within membrane GO:0051668 20 10 0,000 7,942E-03 0,01895581 ! negative regulation of muscle development GO:0048635 20 11 0,000 8,732E-03 0,02082278 ! respiratory burst GO:0045730 17 11 0,000 8,732E-03 0,02080217 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 8,732E-03 0,02078159 ! neuron fate specification GO:0048665 17 11 0,000 8,732E-03 0,02076105 ! telencephalon cell migration GO:0022029 20 11 0,000 8,732E-03 0,02074056 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 8,732E-03 0,02072011 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 8,732E-03 0,02069969 ! thyroid gland development GO:0030878 26 11 0,000 8,732E-03 0,02067932 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 8,732E-03 0,02065898 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 8,732E-03 0,02063869 ! Golgi vesicle budding GO:0048194 22 11 0,000 8,732E-03 0,02061844 ! response to pain GO:0048265 24 11 0,000 8,732E-03 0,02059822 ! detection of mechanical stimulus GO:0050982 22 11 0,000 8,732E-03 0,02057805 ! T cell proliferation GO:0042098 26 11 0,000 8,732E-03 0,02055791 ! blood vessel remodeling GO:0001974 29 11 0,000 8,732E-03 0,02053782 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 8,732E-03 0,02051776 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 8,732E-03 0,02049774 ! bone resorption GO:0045453 16 11 0,000 8,732E-03 0,02047777 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 8,732E-03 0,02045783 ! ventral spinal cord development GO:0021517 21 11 0,000 8,732E-03 0,02043793 ! negative regulation of proteolysis GO:0045861 25 11 0,000 8,732E-03 0,02041806 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 8,732E-03 0,02039824 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 8,732E-03 0,02037846 ! melanocyte differentiation GO:0030318 21 11 0,000 8,732E-03 0,02035871 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 8,732E-03 0,020339 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 8,732E-03 0,02031933 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 8,732E-03 0,0202997 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 8,732E-03 0,0202801 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 8,732E-03 0,02026055 ! lipid digestion GO:0044241 18 11 0,000 8,732E-03 0,02024103 ! substrate-bound cell migration GO:0006929 13 11 0,000 8,732E-03 0,02022155 ! UV protection GO:0009650 19 11 0,000 8,732E-03 0,0202021 ! adult heart development GO:0007512 14 11 0,000 8,732E-03 0,0201827 ! chondrocyte differentiation GO:0002062 24 11 0,000 8,732E-03 0,02016333 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 8,732E-03 0,020144 ! temperature homeostasis GO:0001659 17 11 0,000 8,732E-03 0,0201247 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 8,732E-03 0,02010544 ! negative regulation of ossification GO:0030279 26 11 0,000 8,732E-03 0,02008622 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 8,732E-03 0,02006704 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 8,732E-03 0,02004789 ! regulation of organ growth GO:0046620 13 11 0,000 8,732E-03 0,02002878 ! pigment granule localization GO:0051875 20 11 0,000 8,732E-03 0,0200097 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 8,732E-03 0,01999066 ! vasoconstriction GO:0042310 18 11 0,000 8,732E-03 0,01997166 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 8,732E-03 0,01995269 ! embryonic axis specification GO:0000578 18 11 0,000 8,732E-03 0,01993376 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 8,732E-03 0,01991487 ! snRNA metabolic process GO:0016073 24 11 0,000 8,732E-03 0,01989601 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 8,732E-03 0,01987719 ! nitric oxide metabolic process GO:0046209 15 11 0,000 8,732E-03 0,0198584 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 8,732E-03 0,01983965 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 8,732E-03 0,01982093 ! zymogen activation GO:0031638 15 11 0,000 8,732E-03 0,01980225 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 8,732E-03 0,0197836 ! neuroblast proliferation GO:0007405 24 11 0,000 8,732E-03 0,01976499 ! nucleosome positioning GO:0016584 15 11 0,000 8,732E-03 0,01974642 ! regulation of isotype switching GO:0045191 22 11 0,000 8,732E-03 0,01972788 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 8,732E-03 0,01970937 ! glutathione biosynthetic process GO:0006750 13 11 0,000 8,732E-03 0,0196909 ! regulation of leukocyte migration GO:0002685 26 11 0,000 8,732E-03 0,01967246 ! acid secretion GO:0046717 18 11 0,000 8,732E-03 0,01965406 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 8,732E-03 0,01963569 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 8,732E-03 0,01961736 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 8,732E-03 0,01959906 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 8,732E-03 0,01958079 ! oocyte differentiation GO:0009994 18 11 0,000 8,732E-03 0,01956256 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 8,732E-03 0,01954436 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 8,732E-03 0,0195262 ! cholesterol efflux GO:0033344 19 11 0,000 8,732E-03 0,01950807 ! anterior/posterior axis specification GO:0009948 18 11 0,000 8,732E-03 0,01948997 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 8,732E-03 0,01947191 ! negative regulation of glucose import GO:0046325 17 11 0,000 8,732E-03 0,01945388 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 8,732E-03 0,01943588 ! embryonic gut development GO:0048566 15 11 0,000 8,732E-03 0,01941792 ! regulation of organic acid transport GO:0032890 18 11 0,000 8,732E-03 0,01939999 ! cardiac cell differentiation GO:0035051 31 11 0,000 8,732E-03 0,01938209 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 8,732E-03 0,01936423 ! defense response to fungus GO:0050832 13 11 0,000 8,732E-03 0,0193464 ! developmental induction GO:0031128 19 11 0,000 8,732E-03 0,0193286 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 8,732E-03 0,01931083 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 8,732E-03 0,0192931 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 8,732E-03 0,0192754 ! sequestering of metal ion GO:0051238 14 11 0,000 8,732E-03 0,01925773 ! lamellipodium assembly GO:0030032 20 11 0,000 8,732E-03 0,0192401 ! regulation of embryonic development GO:0045995 27 11 0,000 8,732E-03 0,0192225 ! nucleus localization GO:0051647 19 11 0,000 8,732E-03 0,01920492 ! regulation of synapse organization GO:0050807 17 11 0,000 8,732E-03 0,01918739 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 9,523E-03 0,02090462 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 9,523E-03 0,02088556 ! positive regulation of blood pressure GO:0045777 17 12 0,000 9,523E-03 0,02086654 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 9,523E-03 0,02084755 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 9,523E-03 0,0208286 ! virus-host interaction GO:0019048 29 12 0,000 9,523E-03 0,02080968 ! regulation of B cell proliferation GO:0030888 20 12 0,000 9,523E-03 0,0207908 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 9,523E-03 0,02077195 ! cartilage condensation GO:0001502 20 12 0,000 9,523E-03 0,02075314 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 9,523E-03 0,02073435 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 9,523E-03 0,02071561 ! protein complex disassembly GO:0043241 27 12 0,000 9,523E-03 0,02069689 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 9,523E-03 0,02067821 ! regulation of cell projection assembly GO:0060491 30 12 0,000 9,523E-03 0,02065957 ! hippocampus development GO:0021766 26 12 0,000 9,523E-03 0,02064096 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 9,523E-03 0,02062238 ! cytokine biosynthetic process GO:0042089 21 12 0,000 9,523E-03 0,02060383 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 9,523E-03 0,02058532 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 9,523E-03 0,02056684 ! regulation of exit from mitosis GO:0007096 17 12 0,000 9,523E-03 0,0205484 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 9,523E-03 0,02052998 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 9,523E-03 0,0205116 ! drug transport GO:0015893 16 12 0,000 9,523E-03 0,02049326 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 9,523E-03 0,02047494 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 9,523E-03 0,02045666 ! tyrosine metabolic process GO:0006570 16 12 0,000 9,523E-03 0,02043841 ! polyamine metabolic process GO:0006595 17 12 0,000 9,523E-03 0,0204202 ! focal adhesion formation GO:0048041 35 12 0,000 9,523E-03 0,02040201 ! mitotic spindle organization GO:0007052 21 12 0,000 9,523E-03 0,02038386 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 9,523E-03 0,02036574 ! forebrain cell migration GO:0021885 21 12 0,000 9,523E-03 0,02034766 ! asymmetric protein localization GO:0008105 20 12 0,000 9,523E-03 0,0203296 ! membrane protein proteolysis GO:0033619 25 12 0,000 9,523E-03 0,02031158 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 9,523E-03 0,02029359 ! entry into host cell GO:0030260 32 12 0,000 9,523E-03 0,02027563 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 9,523E-03 0,0202577 ! monoamine transport GO:0015844 18 12 0,000 9,523E-03 0,02023981 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 9,523E-03 0,02022194 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 9,523E-03 0,02020411 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 9,523E-03 0,02018631 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 9,523E-03 0,02016854 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 9,523E-03 0,0201508 ! protein targeting to peroxisome GO:0006625 23 12 0,000 9,523E-03 0,02013309 ! protein homotetramerization GO:0051289 21 12 0,000 9,523E-03 0,02011542 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 9,523E-03 0,02009777 ! regulation of phagocytosis GO:0050764 16 12 0,000 9,523E-03 0,02008016 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 9,523E-03 0,02006258 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 9,523E-03 0,02004502 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 9,523E-03 0,0200275 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 9,523E-03 0,02001001 ! cranial nerve development GO:0021545 20 12 0,000 9,523E-03 0,01999255 ! fucose catabolic process GO:0019317 22 12 0,000 9,523E-03 0,01997512 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 9,523E-03 0,01995772 ! histone acetylation GO:0016573 26 12 0,000 9,523E-03 0,01994035 ! histone methylation GO:0016571 26 12 0,000 9,523E-03 0,01992301 ! mRNA polyadenylation GO:0006378 23 12 0,000 9,523E-03 0,0199057 ! autonomic nervous system development GO:0048483 24 12 0,000 9,523E-03 0,01988842 ! gland morphogenesis GO:0022612 29 12 0,000 9,523E-03 0,01987117 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 9,523E-03 0,01985395 ! peptidyl-lysine modification GO:0018205 21 12 0,000 9,523E-03 0,01983676 ! T cell homeostasis GO:0043029 25 12 0,000 9,523E-03 0,0198196 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 9,523E-03 0,01980247 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 9,523E-03 0,01978537 ! spleen development GO:0048536 22 12 0,000 9,523E-03 0,0197683 ! digestive tract morphogenesis GO:0048546 26 12 0,000 9,523E-03 0,01975126 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 9,523E-03 0,01973425 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 9,523E-03 0,01971726 ! regulation of RNA splicing GO:0043484 20 12 0,000 9,523E-03 0,01970031 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 9,523E-03 0,01968339 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 9,523E-03 0,01966649 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 9,523E-03 0,01964962 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 9,523E-03 0,01963279 ! response to cold GO:0009409 17 12 0,000 9,523E-03 0,01961598 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 9,523E-03 0,0195992 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 9,523E-03 0,01958245 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01031225 0,02118812 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01031225 0,02117004 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01031225 0,02115199 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01031225 0,02113397 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01031225 0,02111599 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01031225 0,02109803 ! lipid localization GO:0010876 28 13 0,000 0,01031225 0,0210801 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01031225 0,02106221 ! organelle fusion GO:0048284 32 13 0,000 0,01031225 0,02104435 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01031225 0,02102651 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01031225 0,02100871 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01031225 0,02099093 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01031225 0,02097319 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01031225 0,02095548 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01031225 0,02093779 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01031225 0,02092014 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01031225 0,02090251 ! methionine metabolic process GO:0006555 27 13 0,000 0,01031225 0,02088492 ! plasma membrane organization GO:0007009 24 13 0,000 0,01031225 0,02086735 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01031225 0,02084982 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01031225 0,02083231 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01031225 0,02081483 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01031225 0,02079739 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01031225 0,02077997 ! response to X-ray GO:0010165 25 13 0,000 0,01031225 0,02076258 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01031225 0,02074522 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01031225 0,02072789 ! exocrine system development GO:0035272 32 13 0,000 0,01031225 0,02071059 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01031225 0,02069331 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01031225 0,02067607 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01031225 0,02065885 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01031225 0,02064167 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01031225 0,02062451 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01031225 0,02060738 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01031225 0,02059028 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01031225 0,0205732 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01031225 0,02055616 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01031225 0,02053914 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01031225 0,02052215 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01031225 0,02050519 ! ribosome assembly GO:0042255 17 13 0,000 0,01031225 0,02048826 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01031225 0,02047136 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01031225 0,02045448 ! chromatin silencing GO:0006342 26 13 0,000 0,01031225 0,02043763 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01031225 0,02042081 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01031225 0,02040402 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01031225 0,02038725 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01031225 0,02037051 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01031225 0,0203538 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01031225 0,02033712 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01031225 0,02032046 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01031225 0,02030383 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01031225 0,02028723 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01031225 0,02027066 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01031225 0,02025411 ! embryonic placenta development GO:0001892 23 13 0,000 0,01031225 0,02023759 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01031225 0,02022109 ! insulin secretion GO:0030073 23 13 0,000 0,01031225 0,02020463 ! actin filament polymerization GO:0030041 24 13 0,000 0,01031225 0,02018819 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01031225 0,02017177 ! acrosome reaction GO:0007340 18 13 0,000 0,01031225 0,02015539 ! rRNA transcription GO:0009303 25 14 0,000 0,01110127 0,02167991 ! lactation GO:0007595 26 14 0,000 0,01110127 0,02166233 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01110127 0,02164478 ! reproductive cellular process GO:0048610 20 14 0,000 0,01110127 0,02162725 ! tRNA modification GO:0006400 20 14 0,000 0,01110127 0,02160975 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01110127 0,02159228 ! regulation of S phase GO:0033261 23 14 0,000 0,01110127 0,02157484 ! water transport GO:0006833 21 14 0,000 0,01110127 0,02155743 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01110127 0,02154004 ! non-recombinational repair GO:0000726 25 14 0,000 0,01110127 0,02152269 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01110127 0,02150536 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01110127 0,02148806 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01110127 0,02147078 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01110127 0,02145354 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01110127 0,02143632 ! palate development GO:0060021 31 14 0,000 0,01110127 0,02141913 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01110127 0,02140197 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01110127 0,02138483 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01110127 0,02136772 ! arginine metabolic process GO:0006525 17 14 0,000 0,01110127 0,02135064 ! regulation of heart rate GO:0002027 24 14 0,000 0,01110127 0,02133359 ! organic alcohol transport GO:0015850 29 14 0,000 0,01110127 0,02131656 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01110127 0,02129956 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01110127 0,02128259 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01110127 0,02126565 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01110127 0,02124873 ! L-amino acid transport GO:0015807 30 14 0,000 0,01110127 0,02123184 ! bone mineralization GO:0030282 17 14 0,000 0,01110127 0,02121497 ! stem cell development GO:0048864 43 14 0,000 0,01110127 0,02119814 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01110127 0,02118133 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01110127 0,02116454 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01110127 0,02114779 ! cerebellum development GO:0021549 21 14 0,000 0,01110127 0,02113105 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01110127 0,02111435 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01110127 0,02109767 ! response to gamma radiation GO:0010332 28 14 0,000 0,01110127 0,02108102 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01110127 0,0210644 ! cofactor transport GO:0051181 26 14 0,000 0,01110127 0,0210478 ! NADP metabolic process GO:0006739 24 14 0,000 0,01110127 0,02103122 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01110127 0,02101468 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01110127 0,02099815 ! intestinal absorption GO:0050892 25 14 0,000 0,01110127 0,02098166 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01110127 0,02096519 ! oxygen transport GO:0015671 21 14 0,000 0,01110127 0,02094875 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01110127 0,02093233 ! male genitalia development GO:0030539 24 14 0,000 0,01110127 0,02091594 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01110127 0,02089957 ! regulation of axon extension GO:0030516 37 14 0,000 0,01110127 0,02088323 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01110127 0,02086692 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01188968 0,02233144 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01188968 0,02231402 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,01188968 0,02229663 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01188968 0,02227926 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01188968 0,02226192 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01188968 0,02224461 ! copper ion transport GO:0006825 20 15 0,000 0,01188968 0,02222733 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01188968 0,02221007 ! sulfate transport GO:0008272 23 15 0,000 0,01188968 0,02219284 ! response to cAMP GO:0051591 22 15 0,000 0,01188968 0,02217564 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01188968 0,02215846 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01188968 0,02214131 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01188968 0,02212419 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01188968 0,02210709 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01188968 0,02209002 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01188968 0,02207297 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01188968 0,02205595 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01188968 0,02203896 ! pituitary gland development GO:0021983 29 15 0,000 0,01188968 0,022022 ! vesicle coating GO:0006901 33 15 0,000 0,01188968 0,02200506 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01188968 0,02198814 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01188968 0,02197125 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01188968 0,02195439 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01188968 0,02193756 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01188968 0,02192075 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01188968 0,02190396 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01188968 0,0218872 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01188968 0,02187047 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01188968 0,02185376 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01188968 0,02183708 ! histone deacetylation GO:0016575 20 15 0,000 0,01188968 0,02182042 ! tissue regeneration GO:0042246 26 15 0,000 0,01188968 0,02180379 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01188968 0,02178718 ! water homeostasis GO:0030104 27 15 0,000 0,01188968 0,0217706 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01188968 0,02175405 ! muscle maintenance GO:0046716 26 15 0,000 0,01188968 0,02173752 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01188968 0,02172101 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01188968 0,02170453 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01188968 0,02168808 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01188968 0,02167165 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01188968 0,02165524 ! cell killing GO:0001906 29 15 0,000 0,01188968 0,02163886 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01188968 0,0216225 ! detection of bacterium GO:0016045 18 15 0,000 0,01188968 0,02160617 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01188968 0,02158987 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01188968 0,02157358 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01188968 0,02155733 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01188968 0,02154109 ! peptide hormone processing GO:0016486 23 15 0,000 0,01188968 0,02152489 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01267749 0,02293387 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01267749 0,02291664 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01267749 0,02289943 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01267749 0,02288225 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01267749 0,0228651 ! bone remodeling GO:0046849 27 16 0,000 0,01267749 0,02284797 ! filopodium assembly GO:0046847 32 16 0,000 0,01267749 0,02283087 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01267749 0,02281379 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01267749 0,02279674 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01267749 0,02277972 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01267749 0,02276272 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01267749 0,02274574 ! startle response GO:0001964 28 16 0,000 0,01267749 0,02272879 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01267749 0,02271187 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01267749 0,02269497 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01267749 0,0226781 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01267749 0,02266125 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01267749 0,02264443 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01267749 0,02262763 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01267749 0,02261085 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01267749 0,02259411 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01267749 0,02257738 ! response to osmotic stress GO:0006970 25 16 0,000 0,01267749 0,02256068 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01267749 0,02254401 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01267749 0,02252736 ! fructose metabolic process GO:0006000 25 16 0,000 0,01267749 0,02251073 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01267749 0,02249413 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,01267749 0,02247756 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01267749 0,022461 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01267749 0,02244448 ! axon cargo transport GO:0008088 43 16 0,000 0,01267749 0,02242797 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01267749 0,02241149 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01267749 0,02239504 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01267749 0,02237861 ! DNA replication initiation GO:0006270 27 16 0,000 0,01267749 0,0223622 ! neuron recognition GO:0008038 35 16 0,000 0,01267749 0,02234582 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01267749 0,02232946 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01267749 0,02231313 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01267749 0,02229681 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01267749 0,02228053 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01267749 0,02226426 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01267749 0,02224803 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01267749 0,02223181 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01267749 0,02221562 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01267749 0,02219945 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01267749 0,0221833 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01267749 0,02216718 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01267749 0,02215108 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01267749 0,02213501 ! defense response to virus GO:0051607 37 16 0,000 0,01267749 0,02211896 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0134647 0,02347541 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0134647 0,02345841 ! metencephalon development GO:0022037 30 17 0,000 0,0134647 0,02344144 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,0134647 0,02342449 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,0134647 0,02340756 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0134647 0,02339066 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0134647 0,02337378 ! signal complex assembly GO:0007172 41 17 0,000 0,0134647 0,02335693 ! endothelial cell migration GO:0043542 28 17 0,000 0,0134647 0,0233401 ! inositol metabolic process GO:0006020 28 17 0,000 0,0134647 0,0233233 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0134647 0,02330652 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0134647 0,02328977 ! glial cell development GO:0021782 27 17 0,000 0,0134647 0,02327303 ! limbic system development GO:0021761 36 17 0,000 0,0134647 0,02325633 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0134647 0,02323964 ! adult walking behavior GO:0007628 33 17 0,000 0,0134647 0,02322299 ! heart looping GO:0001947 30 17 0,000 0,0134647 0,02320635 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0134647 0,02318974 ! myoblast differentiation GO:0045445 45 17 0,000 0,0134647 0,02317315 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0134647 0,02315659 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,0134647 0,02314005 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,0134647 0,02312353 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0134647 0,02310704 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0134647 0,02309057 ! glycine metabolic process GO:0006544 28 17 0,000 0,0134647 0,02307412 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,0134647 0,0230577 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0134647 0,0230413 ! NAD metabolic process GO:0019674 29 17 0,000 0,0134647 0,02302492 ! membrane budding GO:0006900 37 17 0,000 0,0134647 0,02300857 ! DNA integration GO:0015074 29 17 0,000 0,0134647 0,02299224 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,0134647 0,02297593 ! regulation of protein binding GO:0043393 33 17 0,000 0,0134647 0,02295965 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0134647 0,02294339 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0134647 0,02292715 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0134647 0,02291094 ! genitalia development GO:0048806 30 17 0,000 0,0134647 0,02289475 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,0134647 0,02287858 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0134647 0,02286243 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0134647 0,02284631 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,0134647 0,02283021 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0134647 0,02281413 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0134647 0,02279807 ! steroid catabolic process GO:0006706 31 17 0,000 0,0134647 0,02278204 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0134647 0,02276603 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,0134647 0,02275005 ! gas transport GO:0015669 25 17 0,000 0,0134647 0,02273408 ! organic cation transport GO:0015695 31 17 0,000 0,0134647 0,02271814 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0134647 0,02270222 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,0134647 0,02268632 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0134647 0,02267044 ! microspike assembly GO:0030035 36 17 0,000 0,0134647 0,02265459 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0134647 0,02263876 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0134647 0,02262295 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,0142513 0,02392787 ! neuron maturation GO:0042551 42 18 0,000 0,0142513 0,02391118 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,0142513 0,02389452 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,0142513 0,02387788 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,0142513 0,02386127 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,0142513 0,02384467 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,0142513 0,0238281 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,0142513 0,02381155 ! memory GO:0007613 31 18 0,000 0,0142513 0,02379503 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0142513 0,02377853 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,0142513 0,02376205 ! patterning of blood vessels GO:0001569 39 18 0,000 0,0142513 0,02374559 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,0142513 0,02372916 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,0142513 0,02371275 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,0142513 0,02369636 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,0142513 0,02368 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0142513 0,02366366 ! response to retinoic acid GO:0032526 26 18 0,000 0,0142513 0,02364734 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,0142513 0,02363104 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,0142513 0,02361477 ! response to fungus GO:0009620 21 18 0,000 0,0142513 0,02359851 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,0142513 0,02358228 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,0142513 0,02356607 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,0142513 0,02354989 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,0142513 0,02353373 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,0142513 0,02351758 ! vitamin transport GO:0051180 27 18 0,000 0,0142513 0,02350147 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,0142513 0,02348537 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,0142513 0,02346929 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,0142513 0,02345324 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,0142513 0,02343721 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,0142513 0,0234212 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,0142513 0,02340521 ! nerve development GO:0021675 28 18 0,000 0,0142513 0,02338925 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,0142513 0,02337331 ! protein secretion GO:0009306 39 19 0,000 0,01503731 0,02464562 ! positive regulation of translation GO:0045727 30 19 0,000 0,01503731 0,02462884 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01503731 0,02461209 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01503731 0,02459536 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01503731 0,02457865 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,01503731 0,02456196 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01503731 0,0245453 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01503731 0,02452866 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01503731 0,02451204 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01503731 0,02449544 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01503731 0,02447887 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01503731 0,02446232 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01503731 0,02444579 ! cerebral cortex development GO:0021987 36 19 0,000 0,01503731 0,02442928 ! pigmentation during development GO:0048066 41 19 0,000 0,01503731 0,0244128 ! response to vitamin A GO:0033189 27 19 0,000 0,01503731 0,02439634 ! heme metabolic process GO:0042168 36 19 0,000 0,01503731 0,0243799 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01503731 0,02436348 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01503731 0,02434708 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01503731 0,02433071 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01503731 0,02431436 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,01503731 0,02429803 ! peptide cross-linking GO:0018149 37 19 0,000 0,01503731 0,02428172 ! protein export from nucleus GO:0006611 36 19 0,000 0,01503731 0,02426544 ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01503731 0,02424917 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01503731 0,02423293 ! visual learning GO:0008542 36 19 0,000 0,01503731 0,02421671 ! cellular pigmentation GO:0033059 36 19 0,000 0,01503731 0,02420051 ! G1 phase GO:0051318 40 19 0,000 0,01503731 0,02418434 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01503731 0,02416818 ! cell-cell junction organization GO:0045216 35 19 0,000 0,01503731 0,02415205 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01503731 0,02413594 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01503731 0,02411984 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01503731 0,02410378 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01503731 0,02408773 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01503731 0,0240717 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01503731 0,0240557 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01503731 0,02403971 ! cilium assembly GO:0042384 37 19 0,000 0,01503731 0,02402375 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01503731 0,02400781 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01582271 0,02524499 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01582271 0,02522826 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01582271 0,02521156 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01582271 0,02519487 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01582271 0,02517821 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01582271 0,02516157 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01582271 0,02514495 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01582271 0,02512835 ! response to vitamin GO:0033273 31 20 0,000 0,01582271 0,02511177 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01582271 0,02509522 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01582271 0,02507869 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01582271 0,02506218 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01582271 0,02504569 ! response to alkaloid GO:0043279 38 20 0,000 0,01582271 0,02502922 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01582271 0,02501278 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01582271 0,02499636 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01582271 0,02497995 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01582271 0,02496357 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01582271 0,02494722 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01582271 0,02493088 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01582271 0,02491456 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01582271 0,02489827 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01582271 0,02488199 ! body fluid secretion GO:0007589 31 20 0,000 0,01582271 0,02486574 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01582271 0,02484951 ! peptide secretion GO:0002790 35 20 0,000 0,01582271 0,0248333 ! stem cell differentiation GO:0048863 53 20 0,000 0,01582271 0,02481711 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01582271 0,02480094 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01582271 0,0247848 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01582271 0,02476867 ! sensory perception of pain GO:0019233 30 20 0,000 0,01582271 0,02475257 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01582271 0,02473649 ! diencephalon development GO:0021536 34 20 0,000 0,01582271 0,02472042 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01582271 0,02470438 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01582271 0,02468836 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01582271 0,02467236 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01582271 0,02465638 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01582271 0,02464042 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01582271 0,02462448 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01582271 0,02460857 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01582271 0,02459267 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01582271 0,02457679 ! regulation of glucose import GO:0046324 29 20 0,000 0,01582271 0,02456094 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01582271 0,0245451 ! actin filament-based movement GO:0030048 43 20 0,000 0,01582271 0,02452929 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01582271 0,02451349 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01582271 0,02449772 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01582271 0,02448196 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01582271 0,02446623 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01582271 0,02445051 ! regulation of cell killing GO:0031341 42 21 0,000 0,01660752 0,02564678 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01660752 0,02563033 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01660752 0,0256139 ! hormone secretion GO:0046879 38 21 0,000 0,01660752 0,02559749 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01660752 0,02558111 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01660752 0,02556474 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01660752 0,02554839 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01660752 0,02553207 ! axis specification GO:0009798 38 21 0,000 0,01660752 0,02551577 ! ovarian follicle development GO:0001541 35 21 0,000 0,01660752 0,02549948 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01660752 0,02548322 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01660752 0,02546698 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01660752 0,02545076 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01660752 0,02543456 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01660752 0,02541838 ! cell aging GO:0007569 44 21 0,000 0,01660752 0,02540222 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01660752 0,02538608 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01660752 0,02536996 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01660752 0,02535386 ! cytolysis GO:0019835 24 21 0,000 0,01660752 0,02533779 ! vasodilation GO:0042311 39 21 0,000 0,01660752 0,02532173 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01660752 0,02530569 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01660752 0,02528968 ! oogenesis GO:0048477 36 21 0,000 0,01660752 0,02527368 ! DNA modification GO:0006304 34 21 0,000 0,01660752 0,02525771 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01660752 0,02524175 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01660752 0,02522581 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01660752 0,0252099 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01660752 0,025194 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01660752 0,02517813 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01660752 0,02516227 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01660752 0,02514644 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01660752 0,02513062 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01660752 0,02511483 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01660752 0,02509905 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01660752 0,0250833 ! collagen catabolic process GO:0030574 28 21 0,000 0,01660752 0,02506756 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01660752 0,02505184 ! gut development GO:0048565 39 21 0,000 0,01660752 0,02503615 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01739172 0,02620193 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01739172 0,02618554 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01739172 0,02616916 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01739172 0,0261528 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01739172 0,02613647 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01739172 0,02612015 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01739172 0,02610386 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01739172 0,02608758 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01739172 0,02607133 ! regeneration GO:0031099 41 22 0,000 0,01739172 0,0260551 ! keratinization GO:0031424 28 22 0,000 0,01739172 0,02603888 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01739172 0,02602269 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01739172 0,02600652 ! sensory perception of taste GO:0050909 28 22 0,000 0,01739172 0,02599036 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01739172 0,02597423 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01739172 0,02595812 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01739172 0,02594202 ! vacuolar transport GO:0007034 36 22 0,000 0,01739172 0,02592595 ! lysosome organization GO:0007040 41 22 0,000 0,01739172 0,0259099 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01739172 0,02589386 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01739172 0,02587785 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01739172 0,02586186 ! fucose metabolic process GO:0006004 39 22 0,000 0,01739172 0,02584588 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01739172 0,02582993 ! ureteric bud development GO:0001657 43 22 0,000 0,01739172 0,02581399 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01739172 0,02579808 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01739172 0,02578218 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01739172 0,02576631 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01739172 0,02575045 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01739172 0,02573462 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01739172 0,0257188 ! sarcomere organization GO:0045214 30 22 0,000 0,01739172 0,025703 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,01739172 0,02568722 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01739172 0,02567146 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01739172 0,02565572 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01739172 0,02564 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01739172 0,0256243 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01739172 0,02560862 ! protein stabilization GO:0050821 39 22 0,000 0,01739172 0,02559296 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01817533 0,02672973 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01817533 0,0267134 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01817533 0,02669709 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01817533 0,02668081 ! gluconeogenesis GO:0006094 33 23 0,000 0,01817533 0,02666454 ! viral genome replication GO:0019079 41 23 0,000 0,01817533 0,02664829 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01817533 0,02663206 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01817533 0,02661585 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01817533 0,02659966 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01817533 0,02658349 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01817533 0,02656734 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01817533 0,02655121 ! visual behavior GO:0007632 42 23 0,000 0,01817533 0,0265351 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01817533 0,02651901 ! response to ethanol GO:0045471 46 23 0,000 0,01817533 0,02650293 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01817533 0,02648688 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01817533 0,02647085 ! peroxisome organization GO:0007031 37 23 0,000 0,01817533 0,02645483 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01817533 0,02643884 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01817533 0,02642286 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01817533 0,02640691 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01817533 0,02639097 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01817533 0,02637505 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01817533 0,02635916 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01817533 0,02634328 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01817533 0,02632742 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01817533 0,02631158 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01817533 0,02629575 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01817533 0,02627995 ! fatty acid transport GO:0015908 44 23 0,000 0,01817533 0,02626417 ! platelet activation GO:0030168 37 23 0,000 0,01817533 0,0262484 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01817533 0,02623266 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01817533 0,02621693 ! hormone transport GO:0009914 40 23 0,000 0,01817533 0,02620122 ! cell-cell recognition GO:0009988 25 23 0,000 0,01817533 0,02618553 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01817533 0,02616986 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01817533 0,02615421 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01817533 0,02613858 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01817533 0,02612296 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01817533 0,02610737 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01895833 0,02721584 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,01895833 0,02719961 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01895833 0,0271834 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01895833 0,02716721 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,01895833 0,02715104 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01895833 0,02713489 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01895833 0,02711876 ! vesicle docking GO:0048278 47 24 0,000 0,01895833 0,02710265 ! spinal cord development GO:0021510 47 24 0,000 0,01895833 0,02708655 ! vacuole organization GO:0007033 43 24 0,000 0,01895833 0,02707048 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01895833 0,02705442 ! digestive system process GO:0022600 39 24 0,000 0,01895833 0,02703838 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01895833 0,02702237 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01895833 0,02700637 ! regulation of behavior GO:0050795 43 24 0,000 0,01895833 0,02699039 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01895833 0,02697443 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01895833 0,02695848 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01895833 0,02694256 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01895833 0,02692665 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01895833 0,02691077 ! membrane depolarization GO:0051899 39 24 0,000 0,01895833 0,0268949 ! pallium development GO:0021543 49 24 0,000 0,01895833 0,02687905 ! pentose metabolic process GO:0019321 35 24 0,000 0,01895833 0,02686322 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01895833 0,02684741 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01895833 0,02683162 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01895833 0,02681585 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01895833 0,02680009 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01895833 0,02678435 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01895833 0,02676863 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01895833 0,02675293 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01895833 0,02673725 ! regulation of amine transport GO:0051952 40 24 0,000 0,01895833 0,02672159 ! protein tetramerization GO:0051262 52 24 0,000 0,01895833 0,02670594 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,01974074 0,02779182 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,01974074 0,02777557 ! myelination GO:0042552 45 25 0,000 0,01974074 0,02775934 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,01974074 0,02774312 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,01974074 0,02772693 ! phototransduction GO:0007602 33 25 0,000 0,01974074 0,02771075 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,01974074 0,02769459 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,01974074 0,02767845 ! sperm motility GO:0030317 31 25 0,000 0,01974074 0,02766233 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,01974074 0,02764623 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,01974074 0,02763015 ! receptor metabolic process GO:0043112 46 25 0,000 0,01974074 0,02761409 ! response to starvation GO:0042594 42 25 0,000 0,01974074 0,02759804 ! osteoblast differentiation GO:0001649 60 25 0,000 0,01974074 0,02758201 ! neural crest cell development GO:0014032 54 25 0,000 0,01974074 0,027566 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,01974074 0,02755002 ! negative regulation of cell development GO:0010721 73 25 0,000 0,01974074 0,02753404 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,01974074 0,02751809 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,01974074 0,02750216 ! interaction with host GO:0051701 62 25 0,000 0,01974074 0,02748624 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,01974074 0,02747034 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,01974074 0,02745447 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,01974074 0,02743861 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,01974074 0,02742276 ! immunoglobulin production GO:0002377 55 25 0,000 0,01974074 0,02740694 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,01974074 0,02739113 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,01974074 0,02737535 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,01974074 0,02735958 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,01974074 0,02734383 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,01974074 0,02732809 ! telomere organization GO:0032200 43 25 0,000 0,01974074 0,02731238 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,01974074 0,02729668 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,01974074 0,027281 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02052255 0,02834516 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02052255 0,02832889 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02052255 0,02831265 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02052255 0,02829642 ! initiation of viral infection GO:0019059 57 26 0,000 0,02052255 0,02828022 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02052255 0,02826403 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02052255 0,02824786 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02052255 0,02823171 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02052255 0,02821558 ! molting cycle process GO:0022404 50 26 0,000 0,02052255 0,02819946 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,02052255 0,02818337 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,02052255 0,02816729 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,02052255 0,02815123 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,02052255 0,02813519 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,02052255 0,02811917 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,02052255 0,02810316 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,02052255 0,02808718 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,02052255 0,02807121 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,02052255 0,02805526 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,02052255 0,02803933 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02052255 0,02802342 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02052255 0,02800752 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02052255 0,02799164 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02052255 0,02797579 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,02052255 0,02795994 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02052255 0,02794412 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02052255 0,02792831 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02052255 0,02791253 ! blastocyst development GO:0001824 49 26 0,000 0,02052255 0,02789676 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02052255 0,02788101 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02052255 0,02786527 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,02052255 0,02784955 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,02130376 0,02889338 ! neuron fate commitment GO:0048663 48 27 0,000 0,02130376 0,0288771 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,02130376 0,02886084 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,02130376 0,0288446 ! iron ion transport GO:0006826 59 27 0,000 0,02130376 0,02882838 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,02130376 0,02881217 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,02130376 0,02879599 ! protein amino acid acylation GO:0043543 55 27 0,000 0,02130376 0,02877982 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,02130376 0,02876367 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,02130376 0,02874754 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,02130376 0,02873142 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,02130376 0,02871533 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,02130376 0,02869925 ! autophagy GO:0006914 41 27 0,000 0,02130376 0,02868319 ! male gonad development GO:0008584 44 27 0,000 0,02130376 0,02866715 ! response to toxin GO:0009636 47 27 0,000 0,02130376 0,02865112 ! primary neural tube formation GO:0014020 51 27 0,000 0,02130376 0,02863512 ! base-excision repair GO:0006284 41 27 0,000 0,02130376 0,02861913 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,02130376 0,02860316 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,02130376 0,0285872 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,02130376 0,02857127 ! glutathione metabolic process GO:0006749 39 27 0,000 0,02130376 0,02855535 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,02130376 0,02853945 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,02130376 0,02852357 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,02130376 0,02850771 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,02130376 0,02849186 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02208438 0,02951945 ! circadian rhythm GO:0007623 50 28 0,000 0,02208438 0,02950306 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02208438 0,02948669 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02208438 0,02947034 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02208438 0,029454 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02208438 0,02943768 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02208438 0,02942138 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02208438 0,0294051 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02208438 0,02938884 ! synaptogenesis GO:0007416 42 28 0,000 0,02208438 0,02937259 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02208438 0,02935636 ! lipid oxidation GO:0034440 43 28 0,000 0,02208438 0,02934015 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02208438 0,02932396 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,02208438 0,02930779 ! translational initiation GO:0006413 65 29 0,000 0,0228644 0,03032621 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,0228644 0,0303095 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,0228644 0,03029281 ! regulation of pH GO:0006885 43 29 0,000 0,0228644 0,03027614 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,0228644 0,03025948 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,0228644 0,03024285 ! catechol metabolic process GO:0009712 54 29 0,000 0,0228644 0,03022623 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,0228644 0,03020963 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,0228644 0,03019305 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,0228644 0,03017649 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,0228644 0,03015995 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,0228644 0,03014342 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,0228644 0,03012691 ! cell fate determination GO:0001709 60 29 0,000 0,0228644 0,03011042 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,0228644 0,03009395 ! detection of light stimulus GO:0009583 38 29 0,000 0,0228644 0,0300775 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,0228644 0,03006106 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,0228644 0,03004464 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,0228644 0,03002824 ! tissue homeostasis GO:0001894 48 29 0,000 0,0228644 0,03001186 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,0228644 0,0299955 ! phenol metabolic process GO:0018958 55 30 0,000 0,02364382 0,03100111 ! zinc ion transport GO:0006829 45 30 0,000 0,02364382 0,03098422 ! membrane docking GO:0022406 61 30 0,000 0,02364382 0,03096736 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02364382 0,03095051 ! cell junction assembly GO:0034329 78 30 0,000 0,02364382 0,03093368 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02364382 0,03091687 ! acute-phase response GO:0006953 49 30 0,000 0,02364382 0,03090007 ! myofibril assembly GO:0030239 47 30 0,000 0,02364382 0,0308833 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02364382 0,03086654 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02364382 0,0308498 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02364382 0,03083308 ! phospholipid transport GO:0015914 51 30 0,000 0,02364382 0,03081638 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02364382 0,03079969 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02364382 0,03078303 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02364382 0,03076638 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02364382 0,03074975 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02364382 0,03073313 ! eye morphogenesis GO:0048592 60 30 0,000 0,02364382 0,03071654 ! regulation of B cell activation GO:0050864 50 30 0,000 0,02364382 0,03069996 ! response to heat GO:0009408 50 30 0,000 0,02364382 0,0306834 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02442265 0,03167703 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02442265 0,03165996 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02442265 0,03164291 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02442265 0,03162588 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02442265 0,03160887 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,02442265 0,03159188 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02442265 0,0315749 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02442265 0,03155794 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02442265 0,031541 ! ovulation cycle process GO:0022602 49 31 0,000 0,02442265 0,03152408 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02442265 0,03150718 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02442265 0,03149029 ! peptide transport GO:0015833 55 31 0,000 0,02442265 0,03147343 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02442265 0,03145658 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02442265 0,03143975 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02442265 0,03142293 ! mesoderm formation GO:0001707 69 31 0,000 0,02442265 0,03140614 ! natural killer cell activation GO:0030101 45 31 0,000 0,02442265 0,03138936 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02442265 0,0313726 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02442265 0,03135586 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02442265 0,03133914 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02442265 0,03132243 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02442265 0,03130575 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02520088 0,03228611 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,02520088 0,03226893 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02520088 0,03225176 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02520088 0,03223462 ! cholesterol transport GO:0030301 56 32 0,000 0,02520088 0,03221749 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02520088 0,03220038 ! spindle organization GO:0007051 46 32 0,000 0,02520088 0,03218329 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02520088 0,03216621 ! metanephros development GO:0001656 74 32 0,000 0,02520088 0,03214916 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02520088 0,03213212 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02520088 0,0321151 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02520088 0,0320981 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02520088 0,03208112 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,02520088 0,03206415 ! muscle cell development GO:0055001 49 32 0,000 0,02520088 0,0320472 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02520088 0,03203028 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02520088 0,03201336 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02520088 0,03199647 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02520088 0,03197959 ! ovulation cycle GO:0042698 51 32 0,000 0,02520088 0,03196274 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02520088 0,0319459 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02520088 0,03192907 ! hindbrain development GO:0030902 61 32 0,000 0,02520088 0,03191227 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02520088 0,03189548 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02520088 0,03187871 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02520088 0,03186196 ! gene silencing GO:0016458 65 32 0,000 0,02520088 0,03184523 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,02597851 0,03281066 ! post-embryonic development GO:0009791 69 33 0,000 0,02597851 0,03279344 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,02597851 0,03277625 ! protein targeting to membrane GO:0006612 68 33 0,000 0,02597851 0,03275907 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,02597851 0,03274191 ! ceramide metabolic process GO:0006672 64 33 0,000 0,02597851 0,03272477 ! formation of primary germ layer GO:0001704 72 33 0,000 0,02597851 0,03270764 ! cell fate specification GO:0001708 52 33 0,000 0,02597851 0,03269054 ! sterol transport GO:0015918 57 33 0,000 0,02597851 0,03267345 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,02597851 0,03265638 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,02597851 0,03263932 ! adult locomotory behavior GO:0008344 59 33 0,000 0,02597851 0,03262229 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,02597851 0,03260527 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,02597851 0,03258827 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,02675556 0,03354553 ! glial cell differentiation GO:0010001 63 34 0,000 0,02675556 0,03352806 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,02675556 0,0335106 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,02675556 0,03349317 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,02675556 0,03347575 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,02675556 0,03345835 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,02675556 0,03344097 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,02675556 0,03342361 ! mismatch repair GO:0006298 46 34 0,000 0,02675556 0,03340626 ! spermatid development GO:0007286 63 34 0,000 0,02675556 0,03338893 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,02675556 0,03337163 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,02675556 0,03335433 ! placenta development GO:0001890 53 34 0,000 0,02675556 0,03333706 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,02675556 0,03331981 ! regulation of muscle development GO:0048634 70 35 0,000 0,027532 0,03426901 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,027532 0,03425129 ! negative regulation of secretion GO:0051048 63 35 0,000 0,027532 0,03423359 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,027532 0,03421591 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,027532 0,03419824 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,027532 0,0341806 ! odontogenesis GO:0042476 66 35 0,000 0,027532 0,03416297 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,027532 0,03414536 ! female gonad development GO:0008585 58 35 0,000 0,027532 0,03412777 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,027532 0,03411019 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,027532 0,03409264 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,027532 0,0340751 ! cytokine production GO:0001816 59 35 0,000 0,027532 0,03405758 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,027532 0,03404008 ! neural tube formation GO:0001841 67 35 0,000 0,027532 0,0340226 ! vesicle localization GO:0051648 64 35 0,000 0,027532 0,03400513 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,02830786 0,03494546 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,02830786 0,03492754 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,02830786 0,03490964 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,02830786 0,03489175 ! cell junction organization GO:0034330 86 36 0,000 0,02830786 0,03487389 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,02830786 0,03485604 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,02830786 0,03483821 ! positive regulation of cell development GO:0010720 80 36 0,000 0,02830786 0,0348204 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,02830786 0,03480261 ! regulation of proteolysis GO:0030162 72 36 0,000 0,02830786 0,03478483 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,02830786 0,03476708 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,02830786 0,03474934 ! aerobic respiration GO:0009060 55 36 0,000 0,02830786 0,03473162 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,02830786 0,03471392 ! embryonic organ development GO:0048568 57 36 0,000 0,02830786 0,03469623 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,02830786 0,03467857 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,02830786 0,03466092 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,02908312 0,03559205 ! meiosis I GO:0007127 65 37 0,000 0,02908312 0,03557396 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,02908312 0,03555588 ! sister chromatid segregation GO:0000819 58 37 0,000 0,02908312 0,03553783 ! actomyosin structure organization GO:0031032 62 37 0,000 0,02908312 0,03551979 ! organic anion transport GO:0015711 68 37 0,000 0,02908312 0,03550177 ! tissue remodeling GO:0048771 76 37 0,000 0,02908312 0,03548376 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,02908312 0,03546578 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,02908312 0,03544781 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,02908312 0,03542986 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,02908312 0,03541193 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,02908312 0,03539402 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,02908312 0,03537613 ! glycogen metabolic process GO:0005977 61 37 0,000 0,02908312 0,03535825 ! pigment metabolic process GO:0042440 80 37 0,000 0,02908312 0,03534039 ! spermatid differentiation GO:0048515 66 37 0,000 0,02908312 0,03532255 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,02908312 0,03530473 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,02985778 0,03622684 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,02985778 0,03620858 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,02985778 0,03619034 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,02985778 0,03617212 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,02985778 0,03615392 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,02985778 0,03613573 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,02985778 0,03611756 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,02985778 0,03609941 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,02985778 0,03608128 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,02985778 0,03606317 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,02985778 0,03604507 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,02985778 0,036027 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,02985778 0,03600894 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,02985778 0,0359909 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,02985778 0,03597287 ! glucan metabolic process GO:0044042 62 38 0,000 0,02985778 0,03595487 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,03063186 0,03686856 ! mammary gland development GO:0030879 86 39 0,000 0,03063186 0,03685013 ! learning GO:0007612 77 39 0,000 0,03063186 0,03683171 ! ear morphogenesis GO:0042471 60 39 0,000 0,03063186 0,03681331 ! organic ether metabolic process GO:0018904 55 39 0,000 0,03063186 0,03679494 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,03063186 0,03677657 ! segmentation GO:0035282 67 39 0,000 0,03063186 0,03675823 ! ion transmembrane transport GO:0034220 66 39 0,000 0,03063186 0,03673991 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,03063186 0,0367216 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,03063186 0,03670331 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,03063186 0,03668504 ! RNA modification GO:0009451 57 39 0,000 0,03063186 0,03666679 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,03063186 0,03664856 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,03140534 0,0375553 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,03140534 0,03753664 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,03140534 0,037518 ! feeding behavior GO:0007631 59 40 0,000 0,03140534 0,03749938 ! negative regulation of binding GO:0051100 72 40 0,000 0,03140534 0,03748078 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,03140534 0,0374622 ! mesenchymal cell development GO:0014031 87 40 0,000 0,03140534 0,03744364 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,03140534 0,03742509 ! maintenance of protein location GO:0045185 91 40 0,000 0,03140534 0,03740656 ! cytokinesis GO:0000910 72 40 0,000 0,03140534 0,03738805 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03217824 0,03828924 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03217824 0,03827031 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03217824 0,0382514 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03217824 0,03823251 ! gliogenesis GO:0042063 88 41 0,000 0,03217824 0,03821364 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03217824 0,03819479 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03217824 0,03817595 ! T cell differentiation GO:0030217 81 41 0,000 0,03217824 0,03815714 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03217824 0,03813834 ! female gamete generation GO:0007292 61 41 0,000 0,03217824 0,03811956 ! polyol metabolic process GO:0019751 66 41 0,000 0,03217824 0,0381008 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,03217824 0,03808206 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,03295054 0,03897689 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,03295054 0,03895773 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,03295054 0,0389386 ! regulation of tube size GO:0035150 71 42 0,000 0,03295054 0,03891948 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,03295054 0,03890039 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,03295054 0,03888131 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,03295054 0,03886225 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,03295054 0,03884321 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,03295054 0,03882419 ! neuron migration GO:0001764 79 42 0,000 0,03295054 0,03880518 ! regulation of protein secretion GO:0050708 71 42 0,000 0,03295054 0,0387862 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,03295054 0,03876723 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,03372225 0,03965578 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,03372225 0,03963641 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,03372225 0,03961705 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,03372225 0,03959772 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,03372225 0,0395784 ! glucose transport GO:0015758 65 43 0,000 0,03372225 0,03955911 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,03372225 0,03953983 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,03372225 0,03952057 ! neural tube development GO:0021915 77 43 0,000 0,03372225 0,03950133 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,03372225 0,0394821 ! phagocytosis GO:0006909 90 43 0,000 0,03372225 0,0394629 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,03372225 0,03944372 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,03449337 0,04032606 ! hexose transport GO:0008645 67 44 0,000 0,03449337 0,04030648 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,03449337 0,04028691 ! male sex differentiation GO:0046661 76 44 0,000 0,03449337 0,04026737 ! double-strand break repair GO:0006302 81 44 0,000 0,03449337 0,04024784 ! biopolymer methylation GO:0043414 84 44 0,000 0,03449337 0,04022833 ! B cell differentiation GO:0030183 107 44 0,000 0,03449337 0,04020884 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,03449337 0,04018937 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,03449337 0,04016991 ! developmental growth GO:0048589 82 44 0,000 0,03449337 0,04015048 ! maintenance of location in cell GO:0051651 97 44 0,000 0,03449337 0,04013106 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,0352639 0,0410077 ! glycolysis GO:0006096 65 45 0,000 0,0352639 0,04098789 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,0352639 0,0409681 ! leukocyte migration GO:0050900 68 45 0,000 0,0352639 0,04094833 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,0352639 0,04092858 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,0352639 0,04090884 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,0352639 0,04088913 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,0352639 0,04086943 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,0352639 0,04084975 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,0352639 0,04083009 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,0352639 0,04081046 ! cell growth GO:0016049 84 45 0,000 0,0352639 0,04079083 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,03603384 0,04166142 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,03603384 0,04164141 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,03603384 0,04162142 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,03603384 0,04160145 ! pigmentation GO:0043473 100 46 0,000 0,03603384 0,04158149 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,03603384 0,04156156 ! positive regulation of defense response GO:0031349 76 47 0,000 0,03680319 0,04242859 ! endosome transport GO:0016197 108 47 0,000 0,03680319 0,04240827 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,03680319 0,04238797 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,03680319 0,04236769 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,03680319 0,04234743 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,03680319 0,04232719 ! JNK cascade GO:0007254 91 47 0,000 0,03680319 0,04230696 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,03680319 0,04228676 ! methylation GO:0032259 90 47 0,000 0,03680319 0,04226658 ! protein homooligomerization GO:0051260 76 47 0,000 0,03680319 0,04224641 ! mitochondrial transport GO:0006839 82 48 0,000 0,03757195 0,04310831 ! Notch signaling pathway GO:0007219 96 48 0,000 0,03757195 0,04308776 ! cellular component disassembly GO:0022411 86 48 0,000 0,03757195 0,04306723 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,03757195 0,04304672 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,03757195 0,04302624 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,03757195 0,04300577 ! activation of caspase activity GO:0006919 84 48 0,000 0,03757195 0,04298532 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,03757195 0,04296489 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,03757195 0,04294448 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,03757195 0,04292408 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,03757195 0,04290371 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,03834013 0,04376013 ! regulation of action potential GO:0001508 95 49 0,000 0,03834013 0,04373938 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,03834013 0,04371865 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,03834013 0,04369794 ! regulation of ion transport GO:0043269 77 49 0,000 0,03834013 0,04367725 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,03834013 0,04365658 ! peptide metabolic process GO:0006518 76 49 0,000 0,03834013 0,04363593 ! response to temperature stimulus GO:0009266 76 49 0,000 0,03834013 0,0436153 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,03834013 0,04359468 ! endocrine system development GO:0035270 104 49 0,000 0,03834013 0,04357409 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,03834013 0,04355352 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,03834013 0,04353296 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,03834013 0,04351243 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,03910772 0,04436264 ! neuromuscular process GO:0050905 99 50 0,000 0,03910772 0,04434174 ! regulation of ossification GO:0030278 117 50 0,000 0,03910772 0,04432085 ! inner ear development GO:0048839 79 50 0,000 0,03910772 0,04429999 ! histone modification GO:0016570 91 50 0,000 0,03910772 0,04427914 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,03910772 0,04425831 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,03910772 0,0442375 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,03910772 0,04421671 ! positive regulation of binding GO:0051099 78 51 0,000 0,03987472 0,04506274 ! viral infectious cycle GO:0019058 99 51 0,000 0,03987472 0,04504158 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,03987472 0,04502045 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,03987472 0,04499933 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,03987472 0,04497823 ! excretion GO:0007588 83 51 0,000 0,03987472 0,04495716 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,03987472 0,0449361 ! chromatin remodeling GO:0006338 109 51 0,000 0,03987472 0,04491506 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,03987472 0,04489404 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,03987472 0,04487305 ! vesicle organization GO:0016050 107 51 0,000 0,03987472 0,04485207 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,03987472 0,04483111 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,03987472 0,04481017 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,03987472 0,04478925 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,04064113 0,04562882 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,04064113 0,04560754 ! membrane fusion GO:0006944 110 52 0,000 0,04064113 0,04558628 ! covalent chromatin modification GO:0016569 101 52 0,000 0,04064113 0,04556503 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,04064113 0,04554381 ! amino acid activation GO:0043038 92 52 0,000 0,04064113 0,04552261 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,04064113 0,04550143 ! synapse organization GO:0050808 85 52 0,000 0,04064113 0,04548026 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,04140696 0,04631574 ! RNA catabolic process GO:0006401 93 53 0,000 0,04140696 0,04629421 ! regulation of translational initiation GO:0006446 82 53 0,000 0,04140696 0,04627271 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,04140696 0,04625123 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,04140696 0,04622977 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,04140696 0,04620832 ! cell maturation GO:0048469 100 53 0,000 0,04140696 0,0461869 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,04140696 0,0461655 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,04140696 0,04614412 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,0421722 0,04697515 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,0421722 0,04695341 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,0421722 0,04693169 ! cell recognition GO:0008037 85 54 0,000 0,0421722 0,04690999 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,0421722 0,04688832 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,0421722 0,04686666 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,0421722 0,04684502 ! chloride transport GO:0006821 90 55 0,000 0,04293686 0,0476724 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,04293686 0,04765041 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,04293686 0,04762844 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,04293686 0,04760649 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,04293686 0,04758456 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,04293686 0,04756265 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,04293686 0,04754076 ! aging GO:0007568 103 55 0,000 0,04293686 0,0475189 ! gastrulation GO:0007369 112 55 0,000 0,04293686 0,04749705 ! heart morphogenesis GO:0003007 97 55 0,000 0,04293686 0,04747522 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,04293686 0,04745341 ! RNA elongation GO:0006354 79 55 0,000 0,04293686 0,04743163 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,04293686 0,04740986 ! regulation of actin filament length GO:0030832 105 56 0,000 0,04370093 0,04823139 ! sensory perception of smell GO:0007608 80 56 0,000 0,04370093 0,04820928 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,04370093 0,04818718 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,04370093 0,04816511 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,04370093 0,04814306 ! regulation of DNA replication GO:0006275 101 56 0,000 0,04370093 0,04812102 ! proton transport GO:0015992 94 56 0,000 0,04370093 0,04809901 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,04370093 0,04807702 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,04446442 0,0488946 ! muscle fiber development GO:0048747 112 57 0,000 0,04446442 0,04887226 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,04446442 0,04884995 ! lipid modification GO:0030258 97 57 0,000 0,04446442 0,04882765 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,04446442 0,04880538 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,04446442 0,04878312 ! maintenance of location GO:0051235 118 57 0,000 0,04446442 0,04876089 ! hydrogen transport GO:0006818 97 58 0,000 0,04522732 0,04957491 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,04522732 0,04955234 ! regulation of endocytosis GO:0030100 91 58 0,000 0,04522732 0,04952978 ! adult behavior GO:0030534 99 58 0,000 0,04522732 0,04950725 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,04522732 0,04948473 ! positive regulation of secretion GO:0051047 95 59 0,000 0,04598964 0,05029594 ! regulation of cellular component size GO:0032535 109 59 0,000 0,04598964 0,05027309 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,04598964 0,05025026 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,04598964 0,05022745 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,04598964 0,05020466 ! DNA catabolic process GO:0006308 86 59 0,000 0,04598964 0,05018189 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,04598964 0,05015914 ! establishment of organelle localization GO:0051656 109 59 0,000 0,04598964 0,05013642 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,04675137 0,05094375 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,04675137 0,05092069 ! regulation of heart contraction GO:0008016 110 60 0,000 0,04675137 0,05089765 ! camera-type eye development GO:0043010 116 60 0,000 0,04675137 0,05087463 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,04675137 0,05085163 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,04675137 0,05082865 ! kidney development GO:0001822 122 60 0,000 0,04675137 0,05080569 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,04751253 0,05160954 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,04751253 0,05158625 ! mesoderm development GO:0007498 119 61 0,000 0,04751253 0,05156299 ! tRNA processing GO:0008033 89 61 0,000 0,04751253 0,05153974 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,04751253 0,05151651 ! ear development GO:0043583 103 62 0,000 0,0482731 0,0523176 ! viral reproductive process GO:0022415 126 62 0,000 0,0482731 0,05229404 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,0482731 0,05227051 ! gonad development GO:0008406 98 62 0,000 0,0482731 0,052247 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,0482731 0,0522235 ! regulation of mitosis GO:0007088 105 63 0,000 0,04903309 0,05302184 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,04903309 0,05299802 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,04903309 0,05297423 ! detection of external stimulus GO:0009581 91 63 0,000 0,04903309 0,05295045 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,04903309 0,05292669 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,04903309 0,05290296 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,04979249 0,05369822 ! cell redox homeostasis GO:0045454 102 64 0,000 0,04979249 0,05367416 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,04979249 0,05365013 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,04979249 0,05362611 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,04979249 0,05360212 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,04979249 0,05357815 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,05055132 0,05437035 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,05055132 0,05434605 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,05055132 0,05432178 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,05055132 0,05429753 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,05055132 0,0542733 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,05130956 0,0550628 ! actin filament organization GO:0007015 148 66 0,000 0,05130956 0,05503825 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,05130956 0,05501373 ! extracellular matrix organization GO:0030198 133 66 0,000 0,05130956 0,05498922 ! secondary metabolic process GO:0019748 116 66 0,000 0,05130956 0,05496474 ! developmental maturation GO:0021700 116 66 0,000 0,05130956 0,05494028 ! cell projection assembly GO:0030031 120 66 0,000 0,05130956 0,05491584 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,05206723 0,05570198 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,05206723 0,05567722 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,05206723 0,05565249 ! activation of MAPK activity GO:0000187 115 67 0,000 0,05206723 0,05562777 ! lung development GO:0030324 144 67 0,000 0,05206723 0,05560308 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,05206723 0,05557841 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,05206723 0,05555377 ! hexose catabolic process GO:0019320 104 67 0,000 0,05206723 0,05552914 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,05206723 0,05550454 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,05206723 0,05547996 ! adaptive immune response GO:0002250 119 67 0,000 0,05206723 0,0554554 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,05206723 0,05543086 ! amino acid transport GO:0006865 125 68 0,000 0,05282431 0,05621198 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,05282431 0,05618713 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,05282431 0,0561623 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,05282431 0,0561375 ! viral reproduction GO:0016032 134 68 0,000 0,05282431 0,05611271 ! regulation of lipase activity GO:0060191 130 68 0,000 0,05282431 0,05608795 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,05282431 0,05606321 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,05358082 0,05684102 ! negative regulation of cell size GO:0045792 134 69 0,000 0,05358082 0,05681597 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,05358082 0,05679094 ! urogenital system development GO:0001655 137 69 0,000 0,05358082 0,05676594 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,05358082 0,05674095 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,05358082 0,05671599 ! antigen processing and presentation GO:0019882 104 69 0,000 0,05358082 0,05669105 ! appendage morphogenesis GO:0035107 135 70 0,000 0,05433674 0,05746558 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,05433674 0,05744033 ! amine catabolic process GO:0009310 117 71 0,000 0,05509209 0,05821325 ! reproductive structure development GO:0048608 113 71 0,000 0,05509209 0,05818769 ! appendage development GO:0048736 136 71 0,000 0,05509209 0,05816216 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,05509209 0,05813665 ! B cell activation GO:0042113 160 71 0,000 0,05509209 0,05811116 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,05509209 0,0580857 ! regulation of immune effector process GO:0002697 137 71 0,000 0,05509209 0,05806026 ! acute inflammatory response GO:0002526 113 72 0,000 0,05584686 0,05882992 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,05584686 0,05880417 ! carbohydrate transport GO:0008643 110 72 0,000 0,05584686 0,05877845 ! respiratory system development GO:0060541 153 72 0,000 0,05584686 0,05875275 ! learning or memory GO:0007611 147 73 0,000 0,05660105 0,05952016 ! regulation of blood pressure GO:0008217 125 73 0,000 0,05660105 0,05949416 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,05660105 0,05946818 ! axon guidance GO:0007411 139 73 0,000 0,05660105 0,05944222 ! fertilization GO:0009566 90 73 0,000 0,05660105 0,05941628 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,05735466 0,06018112 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,05735466 0,06015489 ! neurotransmitter transport GO:0006836 123 74 0,000 0,05735466 0,06012868 ! meiosis GO:0007126 121 74 0,000 0,05735466 0,06010249 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,05735466 0,06007633 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,05735466 0,06005018 ! eye development GO:0001654 143 74 0,000 0,05735466 0,06002406 ! organelle localization GO:0051640 136 74 0,000 0,05735466 0,05999796 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,0581077 0,06075929 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,0581077 0,0607329 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,0581077 0,06070652 ! meiotic cell cycle GO:0051321 122 75 0,000 0,0581077 0,06068018 ! rhythmic process GO:0048511 128 75 0,000 0,0581077 0,06065385 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,0581077 0,06062755 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,05886016 0,06138602 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,05886016 0,06135942 ! defense response to bacterium GO:0042742 89 76 0,000 0,05886016 0,06133285 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,05886016 0,0613063 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,05886016 0,06127977 ! regulation of catabolic process GO:0009894 161 76 0,000 0,05886016 0,06125326 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,05961204 0,0620089 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,05961204 0,0619821 ! blood coagulation GO:0007596 146 78 0,000 0,06036335 0,06273617 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,06036335 0,06270908 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,06036335 0,06268201 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,06036335 0,06265497 ! protein oligomerization GO:0051259 139 78 0,000 0,06036335 0,06262795 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,06111409 0,06337952 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,06111409 0,06335222 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,06111409 0,06332493 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,06111409 0,06329767 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,06186424 0,06404706 ! muscle cell differentiation GO:0042692 159 80 0,000 0,06186424 0,06401952 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,06186424 0,06399199 ! protein import into nucleus GO:0006606 158 80 0,000 0,06186424 0,06396449 ! inorganic anion transport GO:0015698 138 80 0,000 0,06186424 0,06393702 ! T cell activation GO:0042110 168 81 0,000 0,06261383 0,06468393 ! response to hypoxia GO:0001666 171 81 0,000 0,06261383 0,06465617 ! digestion GO:0007586 112 81 0,000 0,06261383 0,06462843 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,06261383 0,06460072 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,06261383 0,06457303 ! nuclear import GO:0051170 161 81 0,000 0,06261383 0,06454536 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,06261383 0,06451772 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,06336284 0,06526155 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,06336284 0,06523363 ! response to drug GO:0042493 143 82 0,000 0,06336284 0,06520573 ! response to nutrient GO:0007584 125 82 0,000 0,06336284 0,06517785 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,06336284 0,06515 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,06336284 0,06512217 ! response to oxygen levels GO:0070482 176 83 0,000 0,06411128 0,06586325 ! regulation of lyase activity GO:0051339 160 83 0,000 0,06411128 0,06583514 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,06485914 0,0665747 ! hemostasis GO:0007599 158 84 0,000 0,06485914 0,06654631 ! negative regulation of transport GO:0051051 153 84 0,000 0,06485914 0,06651794 ! negative regulation of growth GO:0045926 155 84 0,000 0,06485914 0,0664896 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,06485914 0,06646128 ! nucleosome assembly GO:0006334 122 85 0,000 0,06560643 0,06719841 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,06560643 0,06716982 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,06560643 0,06714125 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,06635315 0,06787656 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,06635315 0,06784772 ! chromatin assembly GO:0031497 124 86 0,000 0,06635315 0,06781889 ! tube morphogenesis GO:0035239 176 86 0,000 0,06635315 0,0677901 ! alcohol catabolic process GO:0046164 130 86 0,000 0,06635315 0,06776132 ! amine transport GO:0015837 155 86 0,000 0,06635315 0,06773257 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,06709929 0,06846518 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,06709929 0,06843616 ! protein localization in nucleus GO:0034504 176 87 0,000 0,06709929 0,06840716 ! regulation of protein transport GO:0051223 154 87 0,000 0,06709929 0,06837819 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,06784487 0,0691087 ! regulation of DNA binding GO:0051101 155 88 0,000 0,06784487 0,06907946 ! gland development GO:0048732 206 88 0,000 0,06784487 0,06905024 ! regulation of neurological system process GO:0031644 148 88 0,000 0,06784487 0,06902104 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,06784487 0,06899187 ! cellular defense response GO:0006968 114 89 0,000 0,06858987 0,06972 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,06858987 0,06969056 ! ossification GO:0001503 188 90 0,000 0,06933431 0,0704172 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,06933431 0,07038749 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,06933431 0,0703578 ! sex differentiation GO:0007548 145 90 0,000 0,06933431 0,07032814 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,06933431 0,0702985 ! bone development GO:0060348 189 91 0,000 0,07007817 0,07102278 ! sterol metabolic process GO:0016125 152 91 0,000 0,07007817 0,07099287 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,07007817 0,070963 ! regulation of defense response GO:0031347 149 92 0,000 0,07082146 0,0716855 ! nucleosome organization GO:0034728 138 92 0,000 0,07082146 0,07165536 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,07082146 0,07162524 ! vitamin metabolic process GO:0006766 139 92 0,000 0,07082146 0,07159514 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,07156419 0,0723156 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,07156419 0,07228524 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,07156419 0,0722549 ! regulation of membrane potential GO:0042391 164 93 0,000 0,07156419 0,07222459 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,07156419 0,07219431 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,07230634 0,07291243 ! female pregnancy GO:0007565 164 94 0,000 0,07230634 0,07288188 ! transcription initiation GO:0006352 153 94 0,000 0,07230634 0,07285136 ! regulation of T cell activation GO:0050863 158 94 0,000 0,07230634 0,07282087 ! forebrain development GO:0030900 188 95 0,000 0,07304793 0,07353695 ! leukocyte differentiation GO:0002521 202 96 0,000 0,07378895 0,07425186 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,07378895 0,07422082 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,07378895 0,07418981 ! positive regulation of immune response GO:0050778 156 96 0,000 0,07378895 0,07415882 ! detection of stimulus GO:0051606 151 96 0,000 0,07378895 0,07412785 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,0745294 0,07484045 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,0745294 0,07480923 ! protein ubiquitination GO:0016567 217 97 0,000 0,0745294 0,07477804 ! hormone metabolic process GO:0042445 157 97 0,000 0,0745294 0,07474687 ! regulation of protein localization GO:0032880 176 97 0,000 0,0745294 0,07471572 ! response to virus GO:0009615 160 98 0,000 0,07526928 0,07542603 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,07526928 0,07539462 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,07526928 0,07536325 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,0760086 0,07607183 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,0760086 0,0760402 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,0760086 0,0760086 GO:0060538|skeletal muscle organ development,