pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/64130-8-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 3,000 1,462E-11 3,571E-08 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 3,000 4,381E-11 5,351E-08 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 3,000 1,021E-10 8,316E-08 ! regulation of respiratory burst GO:0060263 12 8 3,000 2,04E-10 1,246E-07 ! negative regulation of endocytosis GO:0045806 12 9 3,000 3,669E-10 1,793E-07 ! ruffle organization GO:0031529 17 10 3,000 6,109E-10 2,487E-07 ! actin filament organization GO:0007015 167 72 5,000 6,405E-10 2,236E-07 ! lamellipodium assembly GO:0030032 24 12 3,000 1,437E-09 4,388E-07 ! localization within membrane GO:0051668 26 12 3,000 1,437E-09 3,901E-07 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 3,000 2,9E-09 7,086E-07 GO:0046579|positive regulation of Ras protein signal transduction, ! actin filament polymerization GO:0030041 27 15 3,000 3,951E-09 8,775E-07 ! actin polymerization or depolymerization GO:0008154 52 22 3,000 2,103E-08 4,281E-06 ! polyol catabolic process GO:0046174 9 5 2,000 2,307E-08 4,335E-06 GO:0019405|alditol catabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 3,000 2,543E-08 4,437E-06 ! cell projection assembly GO:0030031 138 68 4,000 3,544E-08 5,772E-06 ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 6,547E-07 9,997E-05 ! fructose metabolic process GO:0006000 25 16 2,000 1,278E-06 1,837E-04 ! regulation of endocytosis GO:0030100 104 60 3,000 1,35E-06 1,832E-04 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 2,000 3,022E-06 3,885E-04 ! regulation of vesicle-mediated transport GO:0060627 136 77 3,000 3,684E-06 4,5E-04 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 2,000 4,016E-06 4,672E-04 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 5,206E-06 5,781E-04 ! negative regulation of transport GO:0051051 164 85 3,000 5,468E-06 5,808E-04 ! osteoblast differentiation GO:0001649 63 26 2,000 5,879E-06 5,985E-04 ! alditol metabolic process GO:0019400 44 26 2,000 5,879E-06 5,745E-04 ! sperm motility GO:0030317 37 28 2,000 7,394E-06 6,947E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 9,631E-06 8,714E-04 ! hexose biosynthetic process GO:0019319 53 32 2,000 1,115E-05 9,73E-04 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 1,599E-05 1,347E-03 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 2,000 1,739E-05 1,416E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! skeletal myofibril assembly GO:0014866 12 5 1,000 1,781E-05 1,404E-03 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 1,000 1,781E-05 1,36E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,781E-05 1,319E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 2,000 1,886E-05 1,355E-03 ! alcohol biosynthetic process GO:0046165 65 42 2,000 2,557E-05 1,785E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 2,669E-05 1,811E-03 GO:0046530|photoreceptor cell differentiation, ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 2,669E-05 1,763E-03 ! polyol metabolic process GO:0019751 77 45 2,000 3,151E-05 2,026E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 1,000 4,974E-05 3,116E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 6,425E-05 3,924E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 7,981E-05 4,755E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 7,981E-05 4,642E-03 ! Golgi vesicle budding GO:0048194 26 11 1,000 9,746E-05 5,537E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 9,746E-05 5,411E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 1,089E-04 5,912E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 1,137E-04 6,041E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 1,137E-04 5,912E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,168E-04 5,947E-03 ! establishment of cell polarity GO:0030010 21 12 1,000 1,168E-04 5,826E-03 ! negative regulation of kinase activity GO:0033673 145 70 2,000 1,187E-04 5,801E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 1,291E-04 6,184E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 1,291E-04 6,065E-03 ! negative regulation of transferase activity GO:0051348 155 74 2,000 1,401E-04 6,456E-03 ! positive regulation of ligase activity GO:0051351 130 77 2,000 1,576E-04 7,13E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 1,701E-04 7,553E-03 ! regulation of adenylate cyclase activity GO:0045761 165 83 2,000 1,968E-04 8,587E-03 ! regulation of ligase activity GO:0051340 147 84 2,000 2,039E-04 8,741E-03 ! regulation of cyclase activity GO:0031279 168 85 2,000 2,112E-04 8,896E-03 ! regulation of cAMP biosynthetic process GO:0030817 173 86 2,000 2,186E-04 9,052E-03 ! regulation of lyase activity GO:0051339 169 86 2,000 2,186E-04 8,902E-03 ! alcohol catabolic process GO:0046164 142 87 2,000 2,262E-04 9,06E-03 ! filopodium assembly GO:0046847 42 17 1,000 2,397E-04 9,446E-03 ! membrane budding GO:0006900 42 17 1,000 2,397E-04 9,297E-03 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 2,419E-04 9,234E-03 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 2,000 2,583E-04 9,708E-03 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 2,000 2,583E-04 9,561E-03 ! bone development GO:0060348 206 92 2,000 2,667E-04 9,726E-03 ! microspike assembly GO:0030035 46 18 1,000 2,695E-04 9,681E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 2,754E-04 9,75E-03 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 2,842E-04 9,918E-03 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 2,932E-04 0,01008776 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 3,009E-04 0,01021027 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 3,212E-04 0,01075058 ! cell-cell junction organization GO:0045216 43 20 1,000 3,341E-04 0,01102862 ! inactivation of MAPK activity GO:0000188 45 22 1,000 4,055E-04 0,01320692 ! G1 phase GO:0051318 44 22 1,000 4,055E-04 0,01303314 ! positive regulation of B cell activation GO:0050871 42 22 1,000 4,055E-04 0,01286388 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 4,836E-04 0,01514666 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 5,252E-04 0,01624136 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 5,685E-04 0,01735991 GO:0045936|negative regulation of phosphate metabolic process, ! insulin receptor signaling pathway GO:0008286 66 27 1,000 6,134E-04 0,01850129 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 6,6E-04 0,01966454 ! myofibril assembly GO:0030239 50 30 1,000 7,583E-04 0,0223187 GO:0055002|striated muscle cell development, ! neurotransmitter secretion GO:0007269 55 30 1,000 7,583E-04 0,022053 ! regulation of B cell activation GO:0050864 55 30 1,000 7,583E-04 0,02179356 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 8,099E-04 0,02300585 ! eye morphogenesis GO:0048592 65 31 1,000 8,099E-04 0,02274142 ! response to heat GO:0009408 54 31 1,000 8,099E-04 0,02248299 ! muscle cell development GO:0055001 52 32 1,000 8,631E-04 0,02369199 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 9,745E-04 0,02645346 ! protein targeting to membrane GO:0006612 75 36 1,000 1,093E-03 0,02933011 ! actomyosin structure organization GO:0031032 68 37 1,000 1,154E-03 0,03064271 ! cell junction organization GO:0034330 96 37 1,000 1,154E-03 0,03031321 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 1,217E-03 0,03162965 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 1,217E-03 0,03129671 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 1,282E-03 0,03261672 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! establishment or maintenance of cell polarity GO:0007163 96 41 1,000 1,416E-03 0,03566055 ! striated muscle cell differentiation GO:0051146 91 43 1,000 1,557E-03 0,03880257 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 1,629E-03 0,0402051 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 1,704E-03 0,04161855 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 1,779E-03 0,04304247 ! response to insulin stimulus GO:0032868 98 47 1,000 1,857E-03 0,04447647 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 2,017E-03 0,04783306 ! response to temperature stimulus GO:0009266 84 51 1,000 2,183E-03 0,05127294 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 2,268E-03 0,05277064 ! vesicle organization GO:0016050 127 53 1,000 2,355E-03 0,05427605 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 2,355E-03 0,0537688 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of translational initiation GO:0006446 87 54 1,000 2,443E-03 0,0552723 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 2,443E-03 0,05476522 ! response to UV GO:0009411 120 55 1,000 2,534E-03 0,05626681 ! skeletal muscle fiber development GO:0048741 130 56 1,000 2,625E-03 0,05777542 ! muscle fiber development GO:0048747 131 57 1,000 2,718E-03 0,05929077 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 3,007E-03 0,06500517 ! regulation of mitosis GO:0007088 112 63 1,000 3,309E-03 0,07091395 GO:0051783|regulation of nuclear division, ! response to peptide hormone stimulus GO:0043434 129 64 1,000 3,413E-03 0,07250268 ! negative regulation of cell growth GO:0030308 142 67 1,000 3,733E-03 0,07862736 ! negative regulation of cell size GO:0045792 144 69 1,000 3,955E-03 0,0825733 ! eye development GO:0001654 155 75 1,000 4,654E-03 0,09634805 ! neurotransmitter transport GO:0006836 142 77 1,000 4,899E-03 0,10056443 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 5,023E-03 0,10226304 ! muscle cell differentiation GO:0042692 178 81 1,000 5,406E-03 0,10914082 ! exocytosis GO:0006887 153 83 1,000 5,668E-03 0,11349721 ! negative regulation of growth GO:0045926 168 85 1,000 5,936E-03 0,11789674 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 5,936E-03 0,11694596 ! positive regulation of cell activation GO:0050867 161 86 1,000 6,072E-03 0,11867081 GO:0002696|positive regulation of leukocyte activation, ! response to unfolded protein GO:0006986 139 90 1,000 6,631E-03 0,1285613 ! regulation of cell cycle process GO:0010564 161 90 1,000 6,631E-03 0,12754901 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 6,734E-03 0,12853158 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 6,734E-03 0,12753521 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 6,734E-03 0,12655417 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,734E-03 0,12558811 ! positive regulation of helicase activity GO:0051096 12 5 0,000 6,734E-03 0,12463668 ! neuron fate determination GO:0048664 7 5 0,000 6,734E-03 0,12369956 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,734E-03 0,12277643 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 6,734E-03 0,12186698 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 6,734E-03 0,1209709 ! polyol transport GO:0015791 12 5 0,000 6,734E-03 0,1200879 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,734E-03 0,11921769 ! response to superoxide GO:0000303 10 5 0,000 6,734E-03 0,11836001 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,734E-03 0,11751458 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 6,734E-03 0,11668115 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 6,734E-03 0,11585945 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,734E-03 0,11504924 ! female meiosis GO:0007143 10 5 0,000 6,734E-03 0,11425029 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,734E-03 0,11346236 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,734E-03 0,11268522 ! hypothalamus development GO:0021854 9 5 0,000 6,734E-03 0,11191865 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 6,734E-03 0,11116244 ! cobalt ion transport GO:0006824 11 5 0,000 6,734E-03 0,11041639 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 6,734E-03 0,10968028 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 6,734E-03 0,10895392 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,734E-03 0,10823712 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,734E-03 0,10752969 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 6,734E-03 0,10683144 ! embryonic camera-type eye development GO:0031076 12 5 0,000 6,734E-03 0,10614221 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,734E-03 0,10546181 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,734E-03 0,10479008 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 6,734E-03 0,10412685 ! transposition GO:0032196 9 5 0,000 6,734E-03 0,10347196 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 6,734E-03 0,10282526 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 6,734E-03 0,1021866 ! negative chemotaxis GO:0050919 16 5 0,000 6,734E-03 0,10155581 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,734E-03 0,10093277 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,734E-03 0,10031733 ! behavioral response to pain GO:0048266 10 5 0,000 6,734E-03 0,09970934 ! clathrin coat assembly GO:0048268 15 5 0,000 6,734E-03 0,09910869 ! Notch receptor processing GO:0007220 11 5 0,000 6,734E-03 0,09851522 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,734E-03 0,09792882 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 6,734E-03 0,09734936 ! micturition GO:0060073 9 5 0,000 6,734E-03 0,09677672 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,734E-03 0,09621077 ! copulation GO:0007620 9 5 0,000 6,734E-03 0,09565141 ! glial cell fate commitment GO:0021781 14 5 0,000 6,734E-03 0,09509851 ! protein maturation by protein folding GO:0022417 14 5 0,000 6,734E-03 0,09455196 ! bioluminescence GO:0008218 9 5 0,000 6,734E-03 0,09401167 ! spermidine metabolic process GO:0008216 7 5 0,000 6,734E-03 0,09347751 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,734E-03 0,09294939 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,734E-03 0,0924272 ! apoptotic cell clearance GO:0043277 23 5 0,000 6,734E-03 0,09191085 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,734E-03 0,09140023 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 6,734E-03 0,09089526 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,734E-03 0,09039583 ! grooming behavior GO:0007625 6 5 0,000 6,734E-03 0,08990187 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 6,734E-03 0,08941327 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,734E-03 0,08892996 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 6,734E-03 0,08845184 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,734E-03 0,08797883 ! response to protozoan GO:0001562 13 5 0,000 6,734E-03 0,08751086 ! positive regulation of glycolysis GO:0045821 13 5 0,000 6,734E-03 0,08704784 ! lymph vessel development GO:0001945 10 5 0,000 6,734E-03 0,08658969 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 6,734E-03 0,08613634 ! endochondral ossification GO:0001958 17 5 0,000 6,734E-03 0,08568772 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,734E-03 0,08524374 ! single strand break repair GO:0000012 8 5 0,000 6,734E-03 0,08480434 ! parathyroid gland development GO:0060017 14 5 0,000 6,734E-03 0,08436945 ! anagen GO:0042640 7 5 0,000 6,734E-03 0,08393899 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,734E-03 0,0835129 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,734E-03 0,08309112 ! cytokine secretion GO:0050663 15 5 0,000 6,734E-03 0,08267358 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 6,734E-03 0,08226021 ! ceramide catabolic process GO:0046514 7 5 0,000 6,734E-03 0,08185095 ! smooth muscle tissue development GO:0048745 32 5 0,000 6,734E-03 0,08144575 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,734E-03 0,08104454 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,734E-03 0,08064726 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,734E-03 0,08025386 ! cardiac muscle fiber development GO:0048739 12 5 0,000 6,734E-03 0,07986428 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,734E-03 0,07947846 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 6,734E-03 0,07909635 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,734E-03 0,0787179 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 6,734E-03 0,07834306 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,734E-03 0,07797176 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,734E-03 0,07760397 ! glycine biosynthetic process GO:0006545 7 5 0,000 6,734E-03 0,07723963 ! microvillus organization GO:0032528 8 5 0,000 6,734E-03 0,0768787 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 6,734E-03 0,07652112 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 6,734E-03 0,07616686 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 6,734E-03 0,07581586 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 6,734E-03 0,07546808 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 6,734E-03 0,07512348 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 6,734E-03 0,07478201 ! polyol biosynthetic process GO:0046173 6 5 0,000 6,734E-03 0,07444363 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 6,734E-03 0,0741083 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,734E-03 0,07377597 ! muscle cell migration GO:0014812 8 5 0,000 6,734E-03 0,07344662 ! mitochondrial fission GO:0000266 8 5 0,000 6,734E-03 0,07312019 ! sister chromatid cohesion GO:0007062 15 5 0,000 6,734E-03 0,07279665 ! response to tumor necrosis factor GO:0034612 10 5 0,000 6,734E-03 0,07247596 ! mRNA transcription GO:0009299 10 5 0,000 6,734E-03 0,07215808 ! nerve growth factor processing GO:0032455 9 5 0,000 6,734E-03 0,07184298 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 6,734E-03 0,07153062 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 6,734E-03 0,07122096 ! anaerobic glycolysis GO:0019642 6 5 0,000 6,734E-03 0,07091397 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,734E-03 0,07060962 ! monocyte activation GO:0042117 10 5 0,000 6,734E-03 0,07030787 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,734E-03 0,07000869 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,734E-03 0,06971204 ! response to food GO:0032094 6 5 0,000 6,734E-03 0,0694179 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,734E-03 0,06912623 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,734E-03 0,068837 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 6,734E-03 0,06855017 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,734E-03 0,06826573 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 6,734E-03 0,06798364 ! forebrain neuron development GO:0021884 13 5 0,000 6,734E-03 0,06770388 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,734E-03 0,0674264 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 6,734E-03 0,06715119 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 6,734E-03 0,06687822 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,734E-03 0,06660746 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,734E-03 0,06633888 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 6,734E-03 0,06607246 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,734E-03 0,06580817 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 6,734E-03 0,06554598 ! lipid glycosylation GO:0030259 7 5 0,000 6,734E-03 0,06528588 ! nucleobase transport GO:0015851 6 5 0,000 6,734E-03 0,06502783 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,734E-03 0,06477182 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 6,734E-03 0,06451781 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 6,734E-03 0,06426579 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 6,734E-03 0,06401573 ! basic amino acid transport GO:0015802 12 5 0,000 6,734E-03 0,0637676 ! cellular glucose homeostasis GO:0001678 6 5 0,000 6,734E-03 0,0635214 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 6,734E-03 0,06327708 ! actin nucleation GO:0045010 11 5 0,000 6,734E-03 0,06303464 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,734E-03 0,06279405 ! depurination GO:0045007 5 5 0,000 6,734E-03 0,06255529 ! depyrimidination GO:0045008 10 5 0,000 6,734E-03 0,06231834 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,734E-03 0,06208318 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,734E-03 0,06184978 ! G2/M transition checkpoint GO:0031576 8 5 0,000 6,734E-03 0,06161813 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,734E-03 0,06138822 ! zinc ion homeostasis GO:0055069 9 5 0,000 6,734E-03 0,06116001 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 6,734E-03 0,06093349 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 6,734E-03 0,06070864 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,734E-03 0,06048545 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,734E-03 0,06026389 ! activated T cell proliferation GO:0050798 16 5 0,000 6,734E-03 0,06004395 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,734E-03 0,05982561 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 6,734E-03 0,05960885 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,734E-03 0,05939365 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,734E-03 0,05918001 ! gamma-delta T cell activation GO:0046629 6 5 0,000 6,734E-03 0,05896789 ! response to arsenic GO:0046685 11 5 0,000 6,734E-03 0,05875729 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 6,734E-03 0,05854819 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,734E-03 0,05834057 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 6,734E-03 0,05813442 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 6,734E-03 0,05792972 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 6,734E-03 0,05772646 ! response to mercury ion GO:0046689 8 5 0,000 6,734E-03 0,05752462 ! response to cadmium ion GO:0046686 7 5 0,000 6,734E-03 0,05732419 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 6,734E-03 0,05712515 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 6,734E-03 0,05692748 ! bile acid biosynthetic process GO:0006699 7 5 0,000 6,734E-03 0,05673118 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,734E-03 0,05653623 ! ganglioside catabolic process GO:0006689 12 5 0,000 6,734E-03 0,05634261 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,734E-03 0,05615031 ! decidualization GO:0046697 11 5 0,000 6,734E-03 0,05595933 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 6,734E-03 0,05576963 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 6,734E-03 0,05558122 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 6,734E-03 0,05539408 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 6,734E-03 0,05520819 ! embryonic cleavage GO:0040016 6 5 0,000 6,734E-03 0,05502355 ! peroxisome fission GO:0016559 5 5 0,000 6,734E-03 0,05484014 ! histone demethylation GO:0016577 13 5 0,000 6,734E-03 0,05465795 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 6,734E-03 0,05447696 ! mitotic recombination GO:0006312 9 5 0,000 6,734E-03 0,05429717 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 6,734E-03 0,05411856 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,734E-03 0,05394112 ! metaphase plate congression GO:0051310 7 5 0,000 6,734E-03 0,05376484 ! regulation of sterol transport GO:0032371 7 5 0,000 6,734E-03 0,05358971 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,734E-03 0,05341572 ! enteric nervous system development GO:0048484 8 5 0,000 6,734E-03 0,05324285 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 6,734E-03 0,0530711 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 6,734E-03 0,05290046 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 6,734E-03 0,0527309 ! muscle cell proliferation GO:0033002 12 5 0,000 6,734E-03 0,05256243 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,734E-03 0,05239504 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 6,734E-03 0,0522287 ! B cell homeostasis GO:0001782 13 5 0,000 6,734E-03 0,05206342 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 6,734E-03 0,05189919 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,734E-03 0,05173598 ! metaphase GO:0051323 11 5 0,000 6,734E-03 0,0515738 ! melatonin biosynthetic process GO:0030187 7 5 0,000 6,734E-03 0,05141263 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 6,734E-03 0,05125247 ! cellular response to nutrient GO:0031670 8 5 0,000 6,734E-03 0,0510933 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,734E-03 0,05093511 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 6,734E-03 0,05077791 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 6,734E-03 0,05062167 ! regulation of hair follicle development GO:0051797 10 5 0,000 6,734E-03 0,05046639 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 6,734E-03 0,05031205 ! response to redox state GO:0051775 6 5 0,000 6,734E-03 0,05015866 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 6,734E-03 0,05000621 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 6,734E-03 0,04985467 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,734E-03 0,04970405 ! brown fat cell differentiation GO:0050873 7 5 0,000 6,734E-03 0,04955434 ! regulation of telomerase activity GO:0051972 7 5 0,000 6,734E-03 0,04940553 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,734E-03 0,04925761 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 6,734E-03 0,04911057 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,734E-03 0,04896441 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 6,734E-03 0,04881912 ! striatum development GO:0021756 14 5 0,000 6,734E-03 0,04867468 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 6,734E-03 0,0485311 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,734E-03 0,04838836 ! glial cell migration GO:0008347 10 5 0,000 6,734E-03 0,04824646 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,734E-03 0,04810539 ! neural plate morphogenesis GO:0001839 7 5 0,000 6,734E-03 0,04796514 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 6,734E-03 0,0478257 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,734E-03 0,04768708 ! T cell activation during immune response GO:0002286 9 5 0,000 6,734E-03 0,04754925 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,734E-03 0,04741222 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,734E-03 0,04727598 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 6,734E-03 0,04714052 ! neuroprotection GO:0043526 8 5 0,000 6,734E-03 0,04700583 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,734E-03 0,04687191 ! regulation of sensory perception GO:0051931 8 5 0,000 6,734E-03 0,04673876 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,734E-03 0,04660635 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 6,734E-03 0,04647469 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 6,734E-03 0,04634378 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,734E-03 0,0462136 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 6,734E-03 0,04608415 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,734E-03 0,04595542 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 6,734E-03 0,04582741 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 6,734E-03 0,04570012 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 6,734E-03 0,04557352 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,734E-03 0,04544763 ! spindle assembly GO:0051225 6 5 0,000 6,734E-03 0,04532243 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,734E-03 0,04519792 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,734E-03 0,04507409 ! protein palmitoylation GO:0018345 12 5 0,000 6,734E-03 0,04495093 ! drug metabolic process GO:0017144 7 5 0,000 6,734E-03 0,04482845 ! stem cell division GO:0017145 11 5 0,000 6,734E-03 0,04470664 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,734E-03 0,04458548 ! organ regeneration GO:0031100 7 5 0,000 6,734E-03 0,04446498 ! carnitine metabolic process GO:0009437 8 5 0,000 6,734E-03 0,04434513 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,734E-03 0,04422592 ! response to protein stimulus GO:0051789 158 96 1,000 7,511E-03 0,04919296 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 8,076E-03 0,05275243 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 8,076E-03 0,05261175 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 8,076E-03 0,05247183 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 8,076E-03 0,05233265 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 8,076E-03 0,0521942 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 8,076E-03 0,05205648 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 8,076E-03 0,05191949 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 8,076E-03 0,05178322 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 8,076E-03 0,05164766 ! response to oxygen radical GO:0000305 11 6 0,000 8,076E-03 0,05151281 ! positive regulation of axon extension GO:0045773 13 6 0,000 8,076E-03 0,05137867 ! myoblast cell fate commitment GO:0048625 18 6 0,000 8,076E-03 0,05124521 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 8,076E-03 0,05111245 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 8,076E-03 0,05098038 ! regulation of interferon-beta production GO:0032648 8 6 0,000 8,076E-03 0,05084899 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 8,076E-03 0,05071827 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 8,076E-03 0,05058822 ! forebrain regionalization GO:0021871 9 6 0,000 8,076E-03 0,05045884 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 8,076E-03 0,05033012 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 8,076E-03 0,05020205 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 8,076E-03 0,05007464 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 8,076E-03 0,04994787 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 8,076E-03 0,04982174 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 8,076E-03 0,04969624 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 8,076E-03 0,04957138 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 8,076E-03 0,04944714 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 8,076E-03 0,04932352 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 8,076E-03 0,04920052 ! malate metabolic process GO:0006108 13 6 0,000 8,076E-03 0,04907813 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 8,076E-03 0,04895635 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 8,076E-03 0,04883517 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 8,076E-03 0,04871459 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 8,076E-03 0,0485946 ! protein refolding GO:0042026 15 6 0,000 8,076E-03 0,0484752 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 8,076E-03 0,04835639 ! opsonization GO:0008228 8 6 0,000 8,076E-03 0,04823816 ! mating behavior GO:0007617 7 6 0,000 8,076E-03 0,04812051 ! erythrocyte maturation GO:0043249 8 6 0,000 8,076E-03 0,04800342 ! embryonic hemopoiesis GO:0035162 16 6 0,000 8,076E-03 0,04788691 ! protein amino acid dealkylation GO:0008214 15 6 0,000 8,076E-03 0,04777096 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 8,076E-03 0,04765557 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 8,076E-03 0,04754074 ! response to interferon-gamma GO:0034341 16 6 0,000 8,076E-03 0,04742646 ! toxin metabolic process GO:0009404 11 6 0,000 8,076E-03 0,04731273 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 8,076E-03 0,04719954 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 8,076E-03 0,04708689 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 8,076E-03 0,04697478 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 8,076E-03 0,0468632 ! cGMP-mediated signaling GO:0019934 14 6 0,000 8,076E-03 0,04675215 ! dorsal spinal cord development GO:0021516 10 6 0,000 8,076E-03 0,04664163 ! activation of MAPKKK activity GO:0000185 12 6 0,000 8,076E-03 0,04653162 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 8,076E-03 0,04642214 ! thymic T cell selection GO:0045061 16 6 0,000 8,076E-03 0,04631316 ! sphingoid catabolic process GO:0046521 8 6 0,000 8,076E-03 0,0462047 ! protein lipoylation GO:0009249 10 6 0,000 8,076E-03 0,04609675 ! transepithelial chloride transport GO:0030321 12 6 0,000 8,076E-03 0,0459893 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 8,076E-03 0,04588234 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 8,076E-03 0,04577589 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 8,076E-03 0,04566992 ! glutamate catabolic process GO:0006538 12 6 0,000 8,076E-03 0,04556445 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 8,076E-03 0,04545946 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 8,076E-03 0,04535496 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 8,076E-03 0,04525093 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 8,076E-03 0,04514739 ! hyperosmotic response GO:0006972 10 6 0,000 8,076E-03 0,04504431 ! L-serine biosynthetic process GO:0006564 7 6 0,000 8,076E-03 0,0449417 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 8,076E-03 0,04483956 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 8,076E-03 0,04473789 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 8,076E-03 0,04463667 ! urea metabolic process GO:0019627 7 6 0,000 8,076E-03 0,04453591 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 8,076E-03 0,0444356 ! neutrophil activation GO:0042119 7 6 0,000 8,076E-03 0,04433575 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 8,076E-03 0,04423634 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 8,076E-03 0,04413738 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 8,076E-03 0,04403886 ! paraxial mesoderm development GO:0048339 16 6 0,000 8,076E-03 0,04394077 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 8,076E-03 0,04384313 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 8,076E-03 0,04374591 ! neuron apoptosis GO:0051402 15 6 0,000 8,076E-03 0,04364913 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 8,076E-03 0,04355278 ! T cell mediated immunity GO:0002456 17 6 0,000 8,076E-03 0,04345684 ! negative regulation of platelet activation GO:0010544 9 6 0,000 8,076E-03 0,04336134 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 8,076E-03 0,04326624 ! carnitine transport GO:0015879 10 6 0,000 8,076E-03 0,04317157 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,076E-03 0,04307731 ! positive regulation of exocytosis GO:0045921 11 6 0,000 8,076E-03 0,04298346 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 8,076E-03 0,04289002 ! early endosome to late endosome transport GO:0045022 16 6 0,000 8,076E-03 0,04279698 ! 5S class rRNA transcription GO:0042791 13 6 0,000 8,076E-03 0,04270435 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 8,076E-03 0,04261211 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 8,076E-03 0,04252027 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 8,076E-03 0,04242883 ! sodium ion homeostasis GO:0055078 12 6 0,000 8,076E-03 0,04233778 ! establishment of spindle localization GO:0051293 16 6 0,000 8,076E-03 0,04224713 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 8,076E-03 0,04215685 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 8,076E-03 0,04206697 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 8,076E-03 0,04197746 ! response to UV-C GO:0010225 14 6 0,000 8,076E-03 0,04188834 ! astrocyte development GO:0014002 16 6 0,000 8,076E-03 0,04179959 ! protein targeting to lysosome GO:0006622 12 6 0,000 8,076E-03 0,04171122 ! purine base biosynthetic process GO:0009113 17 6 0,000 8,076E-03 0,04162322 ! interaction with symbiont GO:0051702 14 6 0,000 8,076E-03 0,04153559 ! regulation of dendrite development GO:0050773 16 6 0,000 8,076E-03 0,04144834 ! peptidyl-arginine modification GO:0018195 13 6 0,000 8,076E-03 0,04136144 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 8,076E-03 0,04127491 ! response to copper ion GO:0046688 10 6 0,000 8,076E-03 0,04118874 ! response to exogenous dsRNA GO:0043330 13 6 0,000 8,076E-03 0,04110293 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 8,076E-03 0,04101748 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,076E-03 0,04093238 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 8,076E-03 0,04084763 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 8,076E-03 0,04076324 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 8,076E-03 0,04067919 ! regulation of dopamine secretion GO:0014059 14 6 0,000 8,076E-03 0,04059549 ! nucleoside catabolic process GO:0009164 10 6 0,000 8,076E-03 0,04051213 ! hair follicle maturation GO:0048820 8 6 0,000 8,076E-03 0,04042911 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 8,076E-03 0,04034644 ! Schwann cell development GO:0014044 15 6 0,000 8,076E-03 0,0402641 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 8,076E-03 0,04018209 ! response to pheromone GO:0019236 6 6 0,000 8,076E-03 0,04010042 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 8,076E-03 0,04001908 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 8,076E-03 0,03993807 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 8,076E-03 0,03985739 ! base conversion or substitution editing GO:0016553 6 6 0,000 8,076E-03 0,03977703 ! subpallium development GO:0021544 15 6 0,000 8,076E-03 0,039697 ! neural tube patterning GO:0021532 8 6 0,000 8,076E-03 0,03961728 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 8,076E-03 0,03953789 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 8,076E-03 0,03945882 ! maintenance of organ identity GO:0048496 9 6 0,000 8,076E-03 0,03938006 ! G2 phase GO:0051319 16 6 0,000 8,076E-03 0,03930161 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 8,076E-03 0,03922347 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 8,076E-03 0,03914565 ! oxygen homeostasis GO:0032364 10 6 0,000 8,076E-03 0,03906813 ! establishment of planar polarity GO:0001736 7 6 0,000 8,076E-03 0,03899092 ! regulation of mast cell activation GO:0033003 13 6 0,000 8,076E-03 0,03891402 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 8,076E-03 0,03883742 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 8,076E-03 0,03876112 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 8,076E-03 0,03868511 ! receptor internalization GO:0031623 11 6 0,000 8,076E-03 0,03860941 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 8,076E-03 0,038534 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 8,076E-03 0,03845888 ! neutrophil homeostasis GO:0001780 11 6 0,000 8,076E-03 0,03838406 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 8,076E-03 0,03830953 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 8,076E-03 0,03823529 ! protein deubiquitination GO:0016579 16 6 0,000 8,076E-03 0,03816133 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 8,076E-03 0,03808766 ! protein destabilization GO:0031648 9 6 0,000 8,076E-03 0,03801427 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 8,076E-03 0,03794117 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 8,076E-03 0,03786834 ! regulation of viral transcription GO:0046782 11 6 0,000 8,076E-03 0,0377958 ! progesterone metabolic process GO:0042448 12 6 0,000 8,076E-03 0,03772353 ! negative regulation of axon extension GO:0030517 24 6 0,000 8,076E-03 0,03765154 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 8,076E-03 0,03757982 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 8,076E-03 0,03750838 ! triglyceride catabolic process GO:0019433 10 6 0,000 8,076E-03 0,03743721 ! determination of adult lifespan GO:0008340 17 6 0,000 8,076E-03 0,0373663 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 8,076E-03 0,03729567 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 8,076E-03 0,0372253 ! neural plate development GO:0001840 9 6 0,000 8,076E-03 0,03715519 ! catecholamine transport GO:0051937 9 6 0,000 8,076E-03 0,03708535 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 8,076E-03 0,03701577 ! sensory cilium assembly GO:0035058 10 6 0,000 8,076E-03 0,03694646 ! organ or tissue specific immune response GO:0002251 8 6 0,000 8,076E-03 0,0368774 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 8,076E-03 0,0368086 ! maternal placenta development GO:0001893 12 6 0,000 8,076E-03 0,03674005 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 8,076E-03 0,03667176 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 8,076E-03 0,03660372 ! negative regulation of B cell activation GO:0050869 14 6 0,000 8,076E-03 0,03653594 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 8,076E-03 0,03646841 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 8,076E-03 0,03640112 ! positive regulation of coagulation GO:0050820 13 6 0,000 8,076E-03 0,03633408 ! cellular anion homeostasis GO:0030002 11 6 0,000 8,076E-03 0,03626729 GO:0055081|anion homeostasis, ! skeletal muscle tissue development GO:0007519 223 100 1,000 8,125E-03 0,03642241 GO:0060538|skeletal muscle organ development, ! tRNA transcription GO:0009304 17 7 0,000 9,416E-03 0,04212901 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 9,416E-03 0,04205199 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 9,416E-03 0,04197525 ! behavioral response to cocaine GO:0048148 14 7 0,000 9,416E-03 0,0418988 ! regulation of helicase activity GO:0051095 16 7 0,000 9,416E-03 0,04182262 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 9,416E-03 0,04174671 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 9,416E-03 0,04167109 ! sleep GO:0030431 16 7 0,000 9,416E-03 0,04159573 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 9,416E-03 0,04152065 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 9,416E-03 0,04144584 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,416E-03 0,04137129 ! prostate gland development GO:0030850 14 7 0,000 9,416E-03 0,04129702 ! nucleotide-sugar transport GO:0015780 11 7 0,000 9,416E-03 0,04122301 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,416E-03 0,04114926 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,416E-03 0,04107578 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 9,416E-03 0,04100256 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,416E-03 0,04092961 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 9,416E-03 0,04085691 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 9,416E-03 0,04078447 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 9,416E-03 0,04071228 ! SMAD protein complex assembly GO:0007183 13 7 0,000 9,416E-03 0,04064035 ! glycolipid transport GO:0046836 11 7 0,000 9,416E-03 0,04056868 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,416E-03 0,04049725 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 9,416E-03 0,04042608 ! neuron adhesion GO:0007158 14 7 0,000 9,416E-03 0,04035516 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 9,416E-03 0,04028448 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 9,416E-03 0,04021405 ! establishment of tissue polarity GO:0007164 8 7 0,000 9,416E-03 0,04014387 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 9,416E-03 0,04007394 ! mRNA stabilization GO:0048255 18 7 0,000 9,416E-03 0,04000424 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 9,416E-03 0,03993479 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 9,416E-03 0,03986558 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 9,416E-03 0,03979661 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 9,416E-03 0,03972787 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 9,416E-03 0,03965938 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,416E-03 0,03959112 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,416E-03 0,03952309 ! lipoprotein transport GO:0042953 14 7 0,000 9,416E-03 0,0394553 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 9,416E-03 0,03938774 ! rhythmic behavior GO:0007622 17 7 0,000 9,416E-03 0,03932041 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 9,416E-03 0,03925331 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 9,416E-03 0,03918644 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 9,416E-03 0,03911979 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 9,416E-03 0,03905338 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,416E-03 0,03898718 ! regulation of odontogenesis GO:0042481 14 7 0,000 9,416E-03 0,03892122 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,416E-03 0,03885547 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 9,416E-03 0,03878995 ! mechanosensory behavior GO:0007638 16 7 0,000 9,416E-03 0,03872464 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 9,416E-03 0,03865956 ! positive regulation of isotype switching GO:0045830 17 7 0,000 9,416E-03 0,0385947 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 9,416E-03 0,03853005 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 9,416E-03 0,03846562 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,416E-03 0,0384014 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,416E-03 0,0383374 ! spinal cord patterning GO:0021511 14 7 0,000 9,416E-03 0,03827361 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 9,416E-03 0,03821003 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 9,416E-03 0,03814666 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,416E-03 0,03808351 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 9,416E-03 0,03802056 ! adrenal gland development GO:0030325 17 7 0,000 9,416E-03 0,03795782 ! cysteine metabolic process GO:0006534 13 7 0,000 9,416E-03 0,03789529 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 9,416E-03 0,03783296 ! ovulation GO:0030728 10 7 0,000 9,416E-03 0,03777084 ! adenohypophysis development GO:0021984 11 7 0,000 9,416E-03 0,03770892 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 9,416E-03 0,0376472 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 9,416E-03 0,03758568 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 9,416E-03 0,03752437 ! microtubule nucleation GO:0007020 21 7 0,000 9,416E-03 0,03746326 ! proline biosynthetic process GO:0006561 10 7 0,000 9,416E-03 0,03740234 ! tryptophan metabolic process GO:0006568 11 7 0,000 9,416E-03 0,03734162 ! thyroid hormone generation GO:0006590 13 7 0,000 9,416E-03 0,0372811 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 9,416E-03 0,03722077 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 9,416E-03 0,03716064 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,416E-03 0,03710071 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 9,416E-03 0,03704096 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 9,416E-03 0,03698141 ! galactose metabolic process GO:0006012 13 7 0,000 9,416E-03 0,03692205 ! vesicle fusion GO:0006906 20 7 0,000 9,416E-03 0,03686288 ! response to dietary excess GO:0002021 8 7 0,000 9,416E-03 0,0368039 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,416E-03 0,03674511 ! intracellular pH reduction GO:0051452 13 7 0,000 9,416E-03 0,03668651 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,416E-03 0,03662809 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 9,416E-03 0,03656986 ! organ growth GO:0035265 15 7 0,000 9,416E-03 0,03651181 ! nucleoside transport GO:0015858 11 7 0,000 9,416E-03 0,03645394 ! nucleoside salvage GO:0043174 11 7 0,000 9,416E-03 0,03639626 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 9,416E-03 0,03633877 ! male sex determination GO:0030238 15 7 0,000 9,416E-03 0,03628145 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 9,416E-03 0,03622431 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 9,416E-03 0,03616736 ! parturition GO:0007567 16 7 0,000 9,416E-03 0,03611058 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 9,416E-03 0,03605398 ! rRNA modification GO:0000154 14 7 0,000 9,416E-03 0,03599756 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 9,416E-03 0,03594131 ! spindle checkpoint GO:0031577 16 7 0,000 9,416E-03 0,03588524 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 9,416E-03 0,03582934 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 9,416E-03 0,03577362 ! monocyte differentiation GO:0030224 16 7 0,000 9,416E-03 0,03571807 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 9,416E-03 0,0356627 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,416E-03 0,03560749 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 9,416E-03 0,03555246 ! hyaluronan metabolic process GO:0030212 9 7 0,000 9,416E-03 0,03549759 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 9,416E-03 0,0354429 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,416E-03 0,03538837 ! fibrinolysis GO:0042730 11 7 0,000 9,416E-03 0,03533401 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 9,416E-03 0,03527981 ! skeletal muscle contraction GO:0003009 8 7 0,000 9,416E-03 0,03522579 ! eating behavior GO:0042755 8 7 0,000 9,416E-03 0,03517192 ! B cell lineage commitment GO:0002326 21 7 0,000 9,416E-03 0,03511823 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,416E-03 0,03506469 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 9,416E-03 0,03501132 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 9,416E-03 0,03495811 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,416E-03 0,03490507 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 9,416E-03 0,03485218 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,416E-03 0,03479945 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 9,416E-03 0,03474689 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 9,416E-03 0,03469448 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 9,416E-03 0,03464223 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 9,416E-03 0,03459013 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,416E-03 0,0345382 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 9,416E-03 0,03448642 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 9,416E-03 0,03443479 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,416E-03 0,03438332 ! histone ubiquitination GO:0016574 9 7 0,000 9,416E-03 0,034332 ! regulation of meiosis GO:0040020 12 7 0,000 9,416E-03 0,03428083 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 9,416E-03 0,03422982 ! T cell lineage commitment GO:0002360 16 7 0,000 9,416E-03 0,03417896 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 9,416E-03 0,03412825 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,416E-03 0,03407769 ! membrane to membrane docking GO:0022614 14 7 0,000 9,416E-03 0,03402728 ! transcription termination GO:0006353 14 7 0,000 9,416E-03 0,03397701 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,416E-03 0,0339269 ! anaphase GO:0051322 18 7 0,000 9,416E-03 0,03387694 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 9,416E-03 0,03382712 ! axonal fasciculation GO:0007413 19 7 0,000 9,416E-03 0,03377744 ! negative regulation of nuclear division GO:0051784 15 7 0,000 9,416E-03 0,03372792 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 9,416E-03 0,03367853 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 9,416E-03 0,0336293 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 9,416E-03 0,0335802 ! diuresis GO:0030146 12 7 0,000 9,416E-03 0,03353125 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,416E-03 0,03348244 ! thiamin metabolic process GO:0006772 7 7 0,000 9,416E-03 0,03343378 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,416E-03 0,03338525 ! antibiotic transport GO:0042891 9 7 0,000 9,416E-03 0,03333687 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,416E-03 0,03328862 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 9,416E-03 0,03324052 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 9,416E-03 0,03319255 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 9,416E-03 0,03314472 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 9,416E-03 0,03309703 ! melanin biosynthetic process GO:0042438 10 7 0,000 9,416E-03 0,03304948 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 9,416E-03 0,03300206 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,416E-03 0,03295478 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,416E-03 0,03290764 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 9,416E-03 0,03286063 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 9,416E-03 0,03281375 ! endosome to lysosome transport GO:0008333 12 7 0,000 9,416E-03 0,03276701 ! protein modification by small protein removal GO:0070646 19 7 0,000 9,416E-03 0,0327204 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 9,416E-03 0,03267392 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 9,416E-03 0,03262757 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 9,416E-03 0,03258136 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 9,416E-03 0,03253527 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,416E-03 0,03248932 ! muscle adaptation GO:0043500 13 7 0,000 9,416E-03 0,0324435 ! embryonic heart tube development GO:0035050 14 7 0,000 9,416E-03 0,0323978 ! retina homeostasis GO:0001895 12 7 0,000 9,416E-03 0,03235223 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 9,416E-03 0,0323068 ! protein amino acid prenylation GO:0018346 19 7 0,000 9,416E-03 0,03226149 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 9,416E-03 0,0322163 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 9,416E-03 0,03217124 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01075364 0,03669154 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01075364 0,03664036 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,01075364 0,03658933 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01075364 0,03653844 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01075364 0,0364877 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01075364 0,03643709 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01075364 0,03638662 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01075364 0,0363363 ! male meiosis GO:0007140 9 8 0,000 0,01075364 0,03628611 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01075364 0,03623606 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01075364 0,03618615 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01075364 0,03613637 ! meiotic prophase I GO:0007128 14 8 0,000 0,01075364 0,03608673 ! response to zinc ion GO:0010043 12 8 0,000 0,01075364 0,03603723 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01075364 0,03598787 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01075364 0,03593863 ! oligopeptide transport GO:0006857 16 8 0,000 0,01075364 0,03588954 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01075364 0,03584058 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01075364 0,03579175 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01075364 0,03574305 ! signal peptide processing GO:0006465 12 8 0,000 0,01075364 0,03569449 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01075364 0,03564605 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01075364 0,03559775 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01075364 0,03554958 ! succinate metabolic process GO:0006105 17 8 0,000 0,01075364 0,03550154 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01075364 0,03545363 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01075364 0,03540585 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01075364 0,0353582 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01075364 0,03531067 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01075364 0,03526328 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01075364 0,03521601 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01075364 0,03516886 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01075364 0,03512185 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01075364 0,03507496 ! reflex GO:0060004 17 8 0,000 0,01075364 0,03502819 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01075364 0,03498155 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01075364 0,03493503 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01075364 0,03488863 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01075364 0,03484236 ! pigment granule organization GO:0048753 17 8 0,000 0,01075364 0,03479621 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01075364 0,03475019 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01075364 0,03470428 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01075364 0,0346585 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01075364 0,03461283 ! histidine catabolic process GO:0006548 10 8 0,000 0,01075364 0,03456729 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01075364 0,03452187 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01075364 0,03447656 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01075364 0,03443138 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01075364 0,03438631 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01075364 0,03434136 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01075364 0,03429653 ! melanin metabolic process GO:0006582 17 8 0,000 0,01075364 0,03425181 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01075364 0,03420722 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01075364 0,03416273 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01075364 0,03411837 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01075364 0,03407411 ! macrophage activation GO:0042116 13 8 0,000 0,01075364 0,03402998 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01075364 0,03398595 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01075364 0,03394204 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01075364 0,03389825 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01075364 0,03385456 ! purine salvage GO:0043101 12 8 0,000 0,01075364 0,03381099 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01075364 0,03376753 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01075364 0,03372419 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01075364 0,03368095 ! osteoblast development GO:0002076 17 8 0,000 0,01075364 0,03363783 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01075364 0,03359481 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01075364 0,0335519 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01075364 0,03350911 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01075364 0,03346642 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01075364 0,03342384 ! response to UV-B GO:0010224 17 8 0,000 0,01075364 0,03338137 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01075364 0,03333901 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01075364 0,03329676 ! intermediate filament organization GO:0045109 12 8 0,000 0,01075364 0,03325461 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01075364 0,03321257 ! cellular extravasation GO:0045123 13 8 0,000 0,01075364 0,03317063 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01075364 0,0331288 ! response to antibiotic GO:0046677 11 8 0,000 0,01075364 0,03308708 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01075364 0,03304546 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01075364 0,03300395 ! DNA topological change GO:0006265 12 8 0,000 0,01075364 0,03296254 ! response to tropane GO:0014073 15 8 0,000 0,01075364 0,03292123 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01075364 0,03288003 ! melanosome transport GO:0032402 13 8 0,000 0,01075364 0,03283893 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,01075364 0,03279793 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01075364 0,03275703 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01075364 0,03271624 ! mast cell activation GO:0045576 14 8 0,000 0,01075364 0,03267555 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01075364 0,03263496 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01075364 0,03259447 ! gas homeostasis GO:0033483 14 8 0,000 0,01075364 0,03255408 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01075364 0,03251379 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01075364 0,0324736 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01075364 0,03243351 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01075364 0,03239352 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01075364 0,03235362 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01075364 0,03231383 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01075364 0,03227413 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01075364 0,03223453 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01075364 0,03219503 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01075364 0,03215562 ! response to tumor cell GO:0002347 16 8 0,000 0,01075364 0,03211631 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01075364 0,0320771 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01075364 0,03203798 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01075364 0,03199895 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01075364 0,03196003 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01075364 0,03192119 ! hormone catabolic process GO:0042447 17 8 0,000 0,01075364 0,03188245 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01075364 0,03184381 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01075364 0,03180526 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01075364 0,0317668 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01075364 0,03172843 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01075364 0,03169016 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01075364 0,03165198 ! adult feeding behavior GO:0008343 10 8 0,000 0,01075364 0,03161389 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01075364 0,03157589 ! ATP catabolic process GO:0006200 11 8 0,000 0,01075364 0,03153799 ! blastocyst growth GO:0001832 19 8 0,000 0,01075364 0,03150017 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01075364 0,03146244 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01075364 0,03142481 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01075364 0,03138727 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01075364 0,03134981 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01075364 0,03131245 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01075364 0,03127517 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01075364 0,03123798 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01075364 0,03120088 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01075364 0,03116387 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01075364 0,03112694 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01075364 0,03109011 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01075364 0,03105336 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01075364 0,0310167 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01075364 0,03098012 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01075364 0,03094363 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01075364 0,03090723 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01075364 0,03087091 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01075364 0,03083467 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01075364 0,03079852 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01075364 0,03076246 ! axon extension GO:0048675 16 9 0,000 0,01208986 0,03454447 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01208986 0,03450411 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01208986 0,03446385 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01208986 0,03442368 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01208986 0,03438361 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01208986 0,03434363 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01208986 0,03430374 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01208986 0,03426395 ! reproductive behavior GO:0019098 22 9 0,000 0,01208986 0,03422424 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01208986 0,03418463 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01208986 0,03414511 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01208986 0,03410568 ! UTP metabolic process GO:0046051 10 9 0,000 0,01208986 0,03406634 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01208986 0,0340271 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01208986 0,03398794 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01208986 0,03394887 ! artery development GO:0060840 25 9 0,000 0,01208986 0,0339099 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01208986 0,03387101 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01208986 0,03383221 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01208986 0,0337935 ! equilibrioception GO:0050957 20 9 0,000 0,01208986 0,03375488 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01208986 0,03371635 ! chemosensory behavior GO:0007635 21 9 0,000 0,01208986 0,0336779 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01208986 0,03363955 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01208986 0,03360128 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01208986 0,03356309 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01208986 0,033525 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01208986 0,03348699 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01208986 0,03344906 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01208986 0,03341122 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01208986 0,03337347 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01208986 0,0333358 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01208986 0,03329822 ! protein targeting to ER GO:0045047 25 9 0,000 0,01208986 0,03326072 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01208986 0,03322331 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01208986 0,03318598 ! T cell selection GO:0045058 27 9 0,000 0,01208986 0,03314873 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01208986 0,03311157 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01208986 0,03307449 ! glycine catabolic process GO:0006546 15 9 0,000 0,01208986 0,0330375 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01208986 0,03300058 ! endosome organization GO:0007032 20 9 0,000 0,01208986 0,03296375 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01208986 0,032927 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01208986 0,03289034 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01208986 0,03285375 ! mannose metabolic process GO:0006013 13 9 0,000 0,01208986 0,03281725 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01208986 0,03278082 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01208986 0,03274448 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01208986 0,03270822 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01208986 0,03267204 ! receptor clustering GO:0043113 20 9 0,000 0,01208986 0,03263593 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01208986 0,03259991 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01208986 0,03256397 ! retinol metabolic process GO:0042572 20 9 0,000 0,01208986 0,03252811 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01208986 0,03249232 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01208986 0,03245662 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01208986 0,03242099 ! macrophage differentiation GO:0030225 15 9 0,000 0,01208986 0,03238544 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01208986 0,03234997 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01208986 0,03231457 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01208986 0,03227926 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01208986 0,03224402 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01208986 0,03220886 ! response to amine stimulus GO:0014075 13 9 0,000 0,01208986 0,03217377 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01208986 0,03213876 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01208986 0,03210383 ! erythrocyte development GO:0048821 17 9 0,000 0,01208986 0,03206897 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01208986 0,03203419 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01208986 0,03199948 ! renal water homeostasis GO:0003091 15 9 0,000 0,01208986 0,03196485 ! postreplication repair GO:0006301 25 9 0,000 0,01208986 0,03193029 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01208986 0,03189581 ! icosanoid secretion GO:0032309 15 9 0,000 0,01208986 0,0318614 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01208986 0,03182707 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01208986 0,03179281 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01208986 0,03175862 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01208986 0,03172451 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01208986 0,03169047 ! sterol catabolic process GO:0016127 14 9 0,000 0,01208986 0,03165651 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01208986 0,03162261 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01208986 0,03158879 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01208986 0,03155504 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01208986 0,03152137 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01208986 0,03148776 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01208986 0,03145423 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01208986 0,03142077 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01208986 0,03138738 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01208986 0,03135406 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01208986 0,03132081 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01208986 0,03128763 ! purine base metabolic process GO:0006144 25 9 0,000 0,01208986 0,03125452 ! pigment granule transport GO:0051904 17 9 0,000 0,01208986 0,03122148 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01208986 0,03118851 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01208986 0,03115561 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01208986 0,03112278 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01208986 0,03109002 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01208986 0,03105733 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01208986 0,03102471 ! mitochondrion localization GO:0051646 18 9 0,000 0,01208986 0,03099215 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01342431 0,03437692 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01342431 0,03434092 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01342431 0,034305 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01342431 0,03426916 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01342431 0,03423338 ! associative learning GO:0008306 21 10 0,000 0,01342431 0,03419769 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01342431 0,03416207 ! phosphate transport GO:0006817 24 10 0,000 0,01342431 0,03412652 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01342431 0,03409104 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01342431 0,03405564 ! CTP metabolic process GO:0046036 11 10 0,000 0,01342431 0,03402031 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01342431 0,03398506 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01342431 0,03394988 ! GTP metabolic process GO:0046039 11 10 0,000 0,01342431 0,03391477 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01342431 0,03387973 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01342431 0,03384477 ! social behavior GO:0035176 29 10 0,000 0,01342431 0,03380988 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01342431 0,03377506 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01342431 0,03374031 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01342431 0,03370563 ! androgen metabolic process GO:0008209 17 10 0,000 0,01342431 0,03367103 ! phospholipid efflux GO:0033700 19 10 0,000 0,01342431 0,0336365 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01342431 0,03360203 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01342431 0,03356764 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01342431 0,03353332 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01342431 0,03349906 ! lung alveolus development GO:0048286 26 10 0,000 0,01342431 0,03346488 ! pathogenesis GO:0009405 17 10 0,000 0,01342431 0,03343077 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01342431 0,03339672 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01342431 0,03336275 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01342431 0,03332884 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01342431 0,03329501 ! endoderm development GO:0007492 18 10 0,000 0,01342431 0,03326124 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01342431 0,03322754 ! arginine catabolic process GO:0006527 17 10 0,000 0,01342431 0,03319391 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01342431 0,03316035 ! proline metabolic process GO:0006560 13 10 0,000 0,01342431 0,03312685 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01342431 0,03309342 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01342431 0,03306006 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01342431 0,03302677 ! V(D)J recombination GO:0033151 34 10 0,000 0,01342431 0,03299354 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01342431 0,03296038 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01342431 0,03292729 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01342431 0,03289427 ! B cell proliferation GO:0042100 19 10 0,000 0,01342431 0,03286131 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01342431 0,03282841 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01342431 0,03279558 ! multicellular organism growth GO:0035264 19 10 0,000 0,01342431 0,03276282 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01342431 0,03273012 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01342431 0,03269749 ! epithelial cell development GO:0002064 21 10 0,000 0,01342431 0,03266492 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01342431 0,03263242 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01342431 0,03259998 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01342431 0,03256761 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01342431 0,0325353 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01342431 0,03250306 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01342431 0,03247087 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01342431 0,03243876 ! motor axon guidance GO:0008045 22 10 0,000 0,01342431 0,0324067 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01342431 0,03237471 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01342431 0,03234278 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01342431 0,03231092 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01342431 0,03227912 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01342431 0,03224738 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01342431 0,0322157 ! segment specification GO:0007379 15 10 0,000 0,01342431 0,03218409 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01342431 0,03215253 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01342431 0,03212104 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01342431 0,03208961 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01342431 0,03205824 ! response to dsRNA GO:0043331 23 10 0,000 0,01342431 0,03202694 ! DNA ligation GO:0006266 18 10 0,000 0,01342431 0,03199569 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01342431 0,03196451 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01342431 0,03193338 ! melanosome localization GO:0032400 16 10 0,000 0,01342431 0,03190232 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01342431 0,03187131 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01342431 0,03184037 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01342431 0,03180949 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01342431 0,03177867 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01342431 0,0317479 ! induction of an organ GO:0001759 17 10 0,000 0,01342431 0,0317172 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01342431 0,03168655 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01342431 0,03165597 ! protein sumoylation GO:0016925 17 10 0,000 0,01342431 0,03162544 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01342431 0,03159497 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01342431 0,03156456 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01342431 0,03153421 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01342431 0,03150392 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01342431 0,03147369 ! salivary gland development GO:0007431 28 10 0,000 0,01342431 0,03144351 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01342431 0,03141339 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01342431 0,03138333 ! midbrain development GO:0030901 14 10 0,000 0,01342431 0,03135333 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01342431 0,03132338 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01342431 0,03129349 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01342431 0,03126366 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01342431 0,03123389 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01342431 0,03120417 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01342431 0,03117451 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01342431 0,0311449 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01342431 0,03111535 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01342431 0,03108586 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01342431 0,03105642 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01342431 0,03102704 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01342431 0,03099772 ! blastocyst formation GO:0001825 18 10 0,000 0,01342431 0,03096844 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01342431 0,03093923 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01342431 0,03091007 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01342431 0,03088096 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01342431 0,03085191 ! response to nicotine GO:0035094 20 10 0,000 0,01342431 0,03082292 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01342431 0,03079397 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01342431 0,03076509 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01475699 0,03378757 ! respiratory burst GO:0045730 17 11 0,000 0,01475699 0,03375593 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01475699 0,03372435 ! neuron fate specification GO:0048665 18 11 0,000 0,01475699 0,03369283 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01475699 0,03366137 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01475699 0,03362997 ! thyroid gland development GO:0030878 26 11 0,000 0,01475699 0,03359863 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01475699 0,03356735 ! synapsis GO:0007129 14 11 0,000 0,01475699 0,03353612 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01475699 0,03350496 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01475699 0,03347385 ! response to pain GO:0048265 27 11 0,000 0,01475699 0,03344279 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01475699 0,0334118 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01475699 0,03338086 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01475699 0,03334998 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01475699 0,03331916 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01475699 0,0332884 ! bone resorption GO:0045453 16 11 0,000 0,01475699 0,03325769 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01475699 0,03322703 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01475699 0,03319644 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01475699 0,0331659 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01475699 0,03313542 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01475699 0,03310499 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01475699 0,03307462 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01475699 0,0330443 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01475699 0,03301404 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01475699 0,03298384 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01475699 0,03295369 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01475699 0,03292359 ! UV protection GO:0009650 20 11 0,000 0,01475699 0,03289355 ! adult heart development GO:0007512 16 11 0,000 0,01475699 0,03286357 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01475699 0,03283364 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01475699 0,03280376 ! macroautophagy GO:0016236 19 11 0,000 0,01475699 0,03277394 ! temperature homeostasis GO:0001659 18 11 0,000 0,01475699 0,03274417 ! behavioral fear response GO:0001662 27 11 0,000 0,01475699 0,03271446 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01475699 0,0326848 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01475699 0,03265519 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01475699 0,03262564 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01475699 0,03259614 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01475699 0,0325667 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01475699 0,0325373 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01475699 0,03250796 ! regulation of organ growth GO:0046620 14 11 0,000 0,01475699 0,03247868 ! pigment granule localization GO:0051875 20 11 0,000 0,01475699 0,03244944 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01475699 0,03242026 ! vasoconstriction GO:0042310 20 11 0,000 0,01475699 0,03239113 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01475699 0,03236206 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01475699 0,03233303 ! embryonic axis specification GO:0000578 19 11 0,000 0,01475699 0,03230406 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01475699 0,03227514 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01475699 0,03224627 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01475699 0,03221746 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01475699 0,03218869 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01475699 0,03215998 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01475699 0,03213131 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01475699 0,0321027 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01475699 0,03207414 ! prophase GO:0051324 17 11 0,000 0,01475699 0,03204563 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01475699 0,03201717 ! nucleosome positioning GO:0016584 15 11 0,000 0,01475699 0,03198876 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01475699 0,0319604 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01475699 0,03193209 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01475699 0,03190383 ! apical protein localization GO:0045176 18 11 0,000 0,01475699 0,03187563 ! acid secretion GO:0046717 20 11 0,000 0,01475699 0,03184747 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01475699 0,03181936 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01475699 0,0317913 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01475699 0,03176329 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01475699 0,03173533 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01475699 0,03170742 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01475699 0,03167955 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01475699 0,03165174 ! cholesterol efflux GO:0033344 21 11 0,000 0,01475699 0,03162398 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01475699 0,03159626 ! oocyte development GO:0048599 20 11 0,000 0,01475699 0,03156859 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01475699 0,03154097 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01475699 0,0315134 ! embryonic gut development GO:0048566 19 11 0,000 0,01475699 0,03148588 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01475699 0,03145841 ! activation of innate immune response GO:0002218 16 11 0,000 0,01475699 0,03143098 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01475699 0,0314036 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01475699 0,03137627 ! lysogeny GO:0030069 22 11 0,000 0,01475699 0,03134898 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01475699 0,03132175 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01475699 0,03129456 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01475699 0,03126742 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01475699 0,03124032 ! nucleus localization GO:0051647 22 11 0,000 0,01475699 0,03121327 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01608791 0,03399894 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01608791 0,03396956 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01608791 0,03394022 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01608791 0,03391094 ! virus-host interaction GO:0019048 30 12 0,000 0,01608791 0,0338817 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01608791 0,03385252 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01608791 0,03382339 ! protein complex disassembly GO:0043241 28 12 0,000 0,01608791 0,0337943 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01608791 0,03376527 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01608791 0,03373629 ! hippocampus development GO:0021766 29 12 0,000 0,01608791 0,03370735 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01608791 0,03367847 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01608791 0,03364964 ! T cell proliferation GO:0042098 32 12 0,000 0,01608791 0,03362085 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01608791 0,03359212 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01608791 0,03356343 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01608791 0,03353479 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01608791 0,0335062 ! drug transport GO:0015893 16 12 0,000 0,01608791 0,03347766 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01608791 0,03344917 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01608791 0,03342073 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01608791 0,03339233 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01608791 0,03336399 ! focal adhesion formation GO:0048041 37 12 0,000 0,01608791 0,03333569 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01608791 0,03330744 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01608791 0,03327923 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01608791 0,03325108 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01608791 0,03322297 ! lipid digestion GO:0044241 21 12 0,000 0,01608791 0,03319491 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01608791 0,0331669 ! entry into host cell GO:0030260 34 12 0,000 0,01608791 0,03313893 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01608791 0,03311102 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01608791 0,03308314 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01608791 0,03305532 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01608791 0,03302754 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01608791 0,03299981 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01608791 0,03297213 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01608791 0,03294449 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01608791 0,0329169 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01608791 0,03288935 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01608791 0,03286185 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01608791 0,0328344 ! cranial nerve development GO:0021545 23 12 0,000 0,01608791 0,03280699 ! fucose catabolic process GO:0019317 25 12 0,000 0,01608791 0,03277963 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01608791 0,03275231 ! histone acetylation GO:0016573 27 12 0,000 0,01608791 0,03272504 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01608791 0,03269782 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01608791 0,03267064 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01608791 0,0326435 ! zymogen activation GO:0031638 18 12 0,000 0,01608791 0,03261641 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01608791 0,03258937 ! T cell homeostasis GO:0043029 28 12 0,000 0,01608791 0,03256237 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01608791 0,03253541 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01608791 0,0325085 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01608791 0,03248163 ! oocyte differentiation GO:0009994 21 12 0,000 0,01608791 0,03245481 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01608791 0,03242803 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01608791 0,0324013 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01608791 0,03237461 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01608791 0,03234796 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01608791 0,03232136 ! defense response to fungus GO:0050832 15 12 0,000 0,01608791 0,0322948 ! developmental induction GO:0031128 22 12 0,000 0,01608791 0,03226829 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01608791 0,03224182 ! response to cold GO:0009409 17 12 0,000 0,01608791 0,03221539 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01608791 0,03218901 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01741708 0,0348199 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01741708 0,03479143 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01741708 0,03476301 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01741708 0,03473463 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01741708 0,0347063 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01741708 0,03467801 ! peroxisomal transport GO:0043574 28 13 0,000 0,01741708 0,03464977 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01741708 0,03462158 ! cartilage condensation GO:0001502 22 13 0,000 0,01741708 0,03459343 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01741708 0,03456533 ! organelle fusion GO:0048284 36 13 0,000 0,01741708 0,03453727 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01741708 0,03450926 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01741708 0,0344813 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01741708 0,03445338 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01741708 0,0344255 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01741708 0,03439767 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01741708 0,03436989 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01741708 0,03434215 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01741708 0,03431445 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01741708 0,0342868 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01741708 0,03425919 ! methionine metabolic process GO:0006555 31 13 0,000 0,01741708 0,03423163 ! plasma membrane organization GO:0007009 27 13 0,000 0,01741708 0,03420411 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01741708 0,03417664 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01741708 0,03414921 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01741708 0,03412183 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01741708 0,03409449 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01741708 0,03406719 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01741708 0,03403993 ! exocrine system development GO:0035272 34 13 0,000 0,01741708 0,03401272 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01741708 0,03398556 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01741708 0,03395843 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01741708 0,03393135 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01741708 0,03390432 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01741708 0,03387732 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01741708 0,03385037 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01741708 0,03382346 ! protein homotetramerization GO:0051289 24 13 0,000 0,01741708 0,0337966 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01741708 0,03376978 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01741708 0,033743 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01741708 0,03371626 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01741708 0,03368956 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01741708 0,03366291 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01741708 0,0336363 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01741708 0,03360973 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01741708 0,0335832 ! histone methylation GO:0016571 29 13 0,000 0,01741708 0,03355672 ! chromatin silencing GO:0006342 29 13 0,000 0,01741708 0,03353027 ! gland morphogenesis GO:0022612 31 13 0,000 0,01741708 0,03350387 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01741708 0,03347751 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01741708 0,03345119 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01741708 0,03342492 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01741708 0,03339868 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01741708 0,03337248 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01741708 0,03334633 ! spleen development GO:0048536 24 13 0,000 0,01741708 0,03332022 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01741708 0,03329415 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01741708 0,03326811 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01741708 0,03324212 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01741708 0,03321617 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01741708 0,03319026 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01741708 0,03316439 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01741708 0,03313857 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01741708 0,03311278 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01741708 0,03308703 ! insulin secretion GO:0030073 24 13 0,000 0,01741708 0,03306132 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01741708 0,03303565 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01741708 0,03301002 ! acrosome reaction GO:0007340 19 13 0,000 0,01741708 0,03298443 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01741708 0,03295888 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01741708 0,03293337 ! rRNA transcription GO:0009303 28 14 0,000 0,01874448 0,03541591 ! regulation of S phase GO:0033261 26 14 0,000 0,01874448 0,03538854 ! water transport GO:0006833 21 14 0,000 0,01874448 0,03536121 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01874448 0,03533392 ! non-recombinational repair GO:0000726 29 14 0,000 0,01874448 0,03530668 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01874448 0,03527948 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01874448 0,03525232 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01874448 0,0352252 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01874448 0,03519813 ! lipid localization GO:0010876 32 14 0,000 0,01874448 0,03517109 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01874448 0,0351441 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01874448 0,03511715 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01874448 0,03509024 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01874448 0,03506337 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01874448 0,03503655 ! arginine metabolic process GO:0006525 21 14 0,000 0,01874448 0,03500976 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01874448 0,03498301 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01874448 0,03495631 ! regulation of heart rate GO:0002027 25 14 0,000 0,01874448 0,03492965 ! fear response GO:0042596 34 14 0,000 0,01874448 0,03490302 ! organic alcohol transport GO:0015850 29 14 0,000 0,01874448 0,03487644 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01874448 0,0348499 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01874448 0,0348234 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01874448 0,03479693 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01874448 0,03477051 ! bone mineralization GO:0030282 18 14 0,000 0,01874448 0,03474413 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01874448 0,03471779 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01874448 0,03469149 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01874448 0,03466523 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01874448 0,03463901 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01874448 0,03461282 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01874448 0,03458668 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01874448 0,03456058 ! ribosome assembly GO:0042255 18 14 0,000 0,01874448 0,03453451 ! cerebellum development GO:0021549 23 14 0,000 0,01874448 0,03450849 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01874448 0,0344825 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01874448 0,03445656 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01874448 0,03443065 ! response to gamma radiation GO:0010332 30 14 0,000 0,01874448 0,03440478 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01874448 0,03437895 ! NADP metabolic process GO:0006739 24 14 0,000 0,01874448 0,03435316 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01874448 0,03432741 ! oxygen transport GO:0015671 22 14 0,000 0,01874448 0,0343017 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01874448 0,03427602 ! male genitalia development GO:0030539 26 14 0,000 0,01874448 0,03425039 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01874448 0,03422479 ! regulation of axon extension GO:0030516 43 14 0,000 0,01874448 0,03419923 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01874448 0,03417371 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01874448 0,03414822 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01874448 0,03412278 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02007013 0,0365088 ! lactation GO:0007595 30 15 0,000 0,02007013 0,03648164 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,02007013 0,03645452 ! reproductive cellular process GO:0048610 22 15 0,000 0,02007013 0,03642743 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02007013 0,03640039 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02007013 0,03637338 ! superoxide anion generation GO:0042554 22 15 0,000 0,02007013 0,03634642 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02007013 0,0363195 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02007013 0,03629262 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02007013 0,03626577 ! copper ion transport GO:0006825 22 15 0,000 0,02007013 0,03623897 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02007013 0,0362122 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02007013 0,03618548 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02007013 0,03615879 ! sulfate transport GO:0008272 27 15 0,000 0,02007013 0,03613215 ! response to cAMP GO:0051591 25 15 0,000 0,02007013 0,03610554 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02007013 0,03607897 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02007013 0,03605244 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02007013 0,03602595 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02007013 0,0359995 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02007013 0,03597309 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02007013 0,03594672 ! vesicle coating GO:0006901 38 15 0,000 0,02007013 0,03592038 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02007013 0,03589409 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02007013 0,03586783 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02007013 0,03584161 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02007013 0,03581543 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02007013 0,03578929 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02007013 0,03576318 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02007013 0,03573712 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02007013 0,03571109 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02007013 0,0356851 ! regulation of vasodilation GO:0042312 27 15 0,000 0,02007013 0,03565914 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02007013 0,03563323 ! histone deacetylation GO:0016575 24 15 0,000 0,02007013 0,03560735 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02007013 0,03558151 ! water homeostasis GO:0030104 28 15 0,000 0,02007013 0,03555571 ! cofactor transport GO:0051181 30 15 0,000 0,02007013 0,03552994 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02007013 0,03550422 ! muscle maintenance GO:0046716 26 15 0,000 0,02007013 0,03547853 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02007013 0,03545287 ! intestinal absorption GO:0050892 31 15 0,000 0,02007013 0,03542726 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02007013 0,03540168 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02007013 0,03537613 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02007013 0,03535063 ! cell killing GO:0001906 32 15 0,000 0,02007013 0,03532516 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02007013 0,03529973 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,02007013 0,03527433 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02007013 0,03524897 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02007013 0,03522365 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02007013 0,03519837 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02007013 0,03517312 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02139402 0,03746638 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02139402 0,03743954 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02139402 0,03741274 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02139402 0,03738598 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02139402 0,03735925 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02139402 0,03733257 ! bone remodeling GO:0046849 28 16 0,000 0,02139402 0,03730592 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02139402 0,03727931 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02139402 0,03725274 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02139402 0,03722621 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02139402 0,03719971 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02139402 0,03717325 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02139402 0,03714683 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,02139402 0,03712045 ! startle response GO:0001964 28 16 0,000 0,02139402 0,03709411 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02139402 0,0370678 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02139402 0,03704153 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02139402 0,03701529 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02139402 0,0369891 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02139402 0,03696294 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02139402 0,03693682 ! pituitary gland development GO:0021983 30 16 0,000 0,02139402 0,03691073 ! response to osmotic stress GO:0006970 27 16 0,000 0,02139402 0,03688468 ! lysosomal transport GO:0007041 31 16 0,000 0,02139402 0,03685867 ! L-amino acid transport GO:0015807 33 16 0,000 0,02139402 0,0368327 ! stem cell development GO:0048864 46 16 0,000 0,02139402 0,03680676 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02139402 0,03678086 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02139402 0,03675499 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02139402 0,03672916 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02139402 0,03670337 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02139402 0,03667761 ! axon cargo transport GO:0008088 46 16 0,000 0,02139402 0,03665189 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02139402 0,03662621 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02139402 0,03660056 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,02139402 0,03657494 ! DNA replication initiation GO:0006270 28 16 0,000 0,02139402 0,03654937 ! neuron recognition GO:0008038 40 16 0,000 0,02139402 0,03652383 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02139402 0,03649832 ! tissue regeneration GO:0042246 27 16 0,000 0,02139402 0,03647285 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02139402 0,03644742 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02139402 0,03642202 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02139402 0,03639665 ! biomineral formation GO:0031214 22 16 0,000 0,02139402 0,03637133 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02139402 0,03634603 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02139402 0,03632078 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02139402 0,03629555 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02139402 0,03627037 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02139402 0,03624521 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02139402 0,03622009 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02139402 0,03619501 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02139402 0,03616996 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02139402 0,03614495 ! peptide hormone processing GO:0016486 27 16 0,000 0,02139402 0,03611997 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02271616 0,03832568 ! metencephalon development GO:0022037 32 17 0,000 0,02271616 0,03829923 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02271616 0,03827282 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02271616 0,03824644 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02271616 0,0382201 ! signal complex assembly GO:0007172 47 17 0,000 0,02271616 0,0381938 ! endothelial cell migration GO:0043542 31 17 0,000 0,02271616 0,03816753 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02271616 0,0381413 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02271616 0,0381151 ! glial cell development GO:0021782 28 17 0,000 0,02271616 0,03808894 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02271616 0,03806282 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02271616 0,03803673 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02271616 0,03801068 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,02271616 0,03798466 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02271616 0,03795868 ! myoblast differentiation GO:0045445 50 17 0,000 0,02271616 0,03793273 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02271616 0,03790682 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02271616 0,03788095 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02271616 0,03785511 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02271616 0,03782931 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02271616 0,03780354 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02271616 0,0377778 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02271616 0,0377521 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02271616 0,03772644 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02271616 0,03770081 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02271616 0,03767521 ! regulation of protein binding GO:0043393 33 17 0,000 0,02271616 0,03764965 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02271616 0,03762413 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02271616 0,03759864 ! genitalia development GO:0048806 32 17 0,000 0,02271616 0,03757318 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02271616 0,03754776 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02271616 0,03752237 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02271616 0,03749702 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02271616 0,0374717 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02271616 0,03744642 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02271616 0,03742117 ! steroid catabolic process GO:0006706 34 17 0,000 0,02271616 0,03739595 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02271616 0,03737077 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02271616 0,03734562 ! gas transport GO:0015669 26 17 0,000 0,02271616 0,0373205 ! organic cation transport GO:0015695 32 17 0,000 0,02271616 0,03729542 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02271616 0,03727038 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02271616 0,03724536 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02271616 0,03722038 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02403656 0,03935745 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02403656 0,03933109 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02403656 0,03930476 ! limbic system development GO:0021761 40 18 0,000 0,02403656 0,03927847 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02403656 0,03925221 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02403656 0,03922599 ! adult walking behavior GO:0007628 36 18 0,000 0,02403656 0,03919981 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02403656 0,03917366 ! heart looping GO:0001947 34 18 0,000 0,02403656 0,03914754 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02403656 0,03912146 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02403656 0,03909541 ! centrosome cycle GO:0007098 26 18 0,000 0,02403656 0,0390694 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02403656 0,03904343 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02403656 0,03901748 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02403656 0,03899158 ! glycine metabolic process GO:0006544 30 18 0,000 0,02403656 0,0389657 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02403656 0,03893986 ! response to retinoic acid GO:0032526 31 18 0,000 0,02403656 0,03891406 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02403656 0,03888829 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,02403656 0,03886255 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02403656 0,03883685 ! DNA integration GO:0015074 32 18 0,000 0,02403656 0,03881118 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02403656 0,03878554 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02403656 0,03875994 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02403656 0,03873438 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02403656 0,03870884 ! neural crest cell migration GO:0001755 41 18 0,000 0,02403656 0,03868334 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02403656 0,03865788 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02403656 0,03863244 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02403656 0,03860704 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02403656 0,03858168 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02403656 0,03855634 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02403656 0,03853104 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02403656 0,03850578 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02403656 0,03848055 ! detection of bacterium GO:0016045 22 18 0,000 0,02403656 0,03845535 ! nerve development GO:0021675 34 18 0,000 0,02403656 0,03843018 ! defense response to virus GO:0051607 43 18 0,000 0,02403656 0,03840504 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02403656 0,03837994 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02403656 0,03835487 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02535521 0,04043262 ! positive regulation of translation GO:0045727 31 19 0,000 0,02535521 0,04040624 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02535521 0,0403799 ! neuron maturation GO:0042551 46 19 0,000 0,02535521 0,04035359 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02535521 0,04032732 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02535521 0,04030108 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02535521 0,04027488 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02535521 0,04024871 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02535521 0,04022258 ! inositol metabolic process GO:0006020 33 19 0,000 0,02535521 0,04019647 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02535521 0,04017041 ! memory GO:0007613 34 19 0,000 0,02535521 0,04014437 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02535521 0,04011837 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02535521 0,04009241 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02535521 0,04006647 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02535521 0,04004057 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02535521 0,04001471 ! cerebral cortex development GO:0021987 40 19 0,000 0,02535521 0,03998887 ! pigmentation during development GO:0048066 42 19 0,000 0,02535521 0,03996308 ! response to vitamin A GO:0033189 32 19 0,000 0,02535521 0,03993731 ! heme metabolic process GO:0042168 40 19 0,000 0,02535521 0,03991158 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02535521 0,03988588 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02535521 0,03986021 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02535521 0,03983458 ! response to fungus GO:0009620 26 19 0,000 0,02535521 0,03980898 ! peptide cross-linking GO:0018149 39 19 0,000 0,02535521 0,03978341 ! protein export from nucleus GO:0006611 40 19 0,000 0,02535521 0,03975787 ! heart process GO:0003015 32 19 0,000 0,02535521 0,03973237 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02535521 0,0397069 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02535521 0,03968146 ! visual learning GO:0008542 38 19 0,000 0,02535521 0,03965606 ! cellular pigmentation GO:0033059 37 19 0,000 0,02535521 0,03963069 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02535521 0,03960535 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02535521 0,03958004 ! vitamin transport GO:0051180 31 19 0,000 0,02535521 0,03955477 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02535521 0,03952953 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02535521 0,03950432 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02535521 0,03947914 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02535521 0,03945399 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02535521 0,03942888 ! cilium assembly GO:0042384 38 19 0,000 0,02535521 0,0394038 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02535521 0,03937875 ! protein secretion GO:0009306 45 20 0,000 0,02667211 0,04139769 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02667211 0,0413714 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02667211 0,04134515 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02667211 0,04131893 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02667211 0,04129275 ! skin development GO:0043588 42 20 0,000 0,02667211 0,0412666 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,02667211 0,04124048 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02667211 0,0412144 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02667211 0,04118834 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02667211 0,04116232 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,02667211 0,04113634 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02667211 0,04111038 ! response to vitamin GO:0033273 36 20 0,000 0,02667211 0,04108446 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02667211 0,04105858 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,02667211 0,04103272 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02667211 0,0410069 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02667211 0,04098111 ! response to alkaloid GO:0043279 38 20 0,000 0,02667211 0,04095535 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02667211 0,04092962 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02667211 0,04090393 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,02667211 0,04087827 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02667211 0,04085264 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02667211 0,04082704 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,02667211 0,04080148 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,02667211 0,04077594 ! actin filament bundle formation GO:0051017 47 20 0,000 0,02667211 0,04075044 ! body fluid secretion GO:0007589 33 20 0,000 0,02667211 0,04072497 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02667211 0,04069954 ! peptide secretion GO:0002790 38 20 0,000 0,02667211 0,04067413 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02667211 0,04064876 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,02667211 0,04062342 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02667211 0,04059811 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02667211 0,04057283 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02667211 0,04054758 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02667211 0,04052236 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02667211 0,04049718 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02667211 0,04047202 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02667211 0,0404469 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02667211 0,04042181 ! regulation of glucose import GO:0046324 30 20 0,000 0,02667211 0,04039675 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02667211 0,04037172 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02667211 0,04034672 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02667211 0,04032176 ! negative regulation of translation GO:0017148 32 20 0,000 0,02667211 0,04029682 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02667211 0,04027192 ! regulation of cell killing GO:0031341 46 21 0,000 0,02798727 0,04223156 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02798727 0,04220549 ! hormone secretion GO:0046879 39 21 0,000 0,02798727 0,04217945 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02798727 0,04215345 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02798727 0,04212748 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02798727 0,04210154 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02798727 0,04207563 ! ovarian follicle development GO:0001541 39 21 0,000 0,02798727 0,04204975 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02798727 0,04202391 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02798727 0,04199809 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02798727 0,04197231 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02798727 0,04194656 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02798727 0,04192084 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02798727 0,04189516 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02798727 0,0418695 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02798727 0,04184388 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02798727 0,04181828 ! sensory perception of pain GO:0019233 33 21 0,000 0,02798727 0,04179272 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02798727 0,04176719 ! diencephalon development GO:0021536 36 21 0,000 0,02798727 0,04174169 ! collagen fibril organization GO:0030199 62 21 0,000 0,02798727 0,04171623 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02798727 0,04169079 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02798727 0,04166538 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02798727 0,04164001 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02798727 0,04161466 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02798727 0,04158935 ! collagen catabolic process GO:0030574 29 21 0,000 0,02798727 0,04156407 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02798727 0,04153882 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02798727 0,0415136 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02798727 0,04148841 ! actin filament-based movement GO:0030048 47 21 0,000 0,02798727 0,04146325 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02798727 0,04143812 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02930069 0,0433565 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02930069 0,04333025 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02930069 0,04330404 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02930069 0,04327786 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,02930069 0,04325171 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02930069 0,04322559 ! microtubule-based transport GO:0010970 59 22 0,000 0,02930069 0,0431995 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02930069 0,04317345 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02930069 0,04314743 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,02930069 0,04312143 ! cellular response to starvation GO:0009267 37 22 0,000 0,02930069 0,04309547 ! vacuolar transport GO:0007034 41 22 0,000 0,02930069 0,04306954 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02930069 0,04304364 ! fucose metabolic process GO:0006004 44 22 0,000 0,02930069 0,04301778 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02930069 0,04299194 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,02930069 0,04296613 ! ureteric bud development GO:0001657 50 22 0,000 0,02930069 0,04294036 ! cell aging GO:0007569 48 22 0,000 0,02930069 0,04291462 ! stem cell differentiation GO:0048863 57 22 0,000 0,02930069 0,0428889 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02930069 0,04286322 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02930069 0,04283757 ! cytolysis GO:0019835 27 22 0,000 0,02930069 0,04281195 ! renal system process GO:0003014 42 22 0,000 0,02930069 0,04278636 ! vasodilation GO:0042311 40 22 0,000 0,02930069 0,0427608 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02930069 0,04273527 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02930069 0,04270977 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02930069 0,0426843 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02930069 0,04265887 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,02930069 0,04263346 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,02930069 0,04260808 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,02930069 0,04258274 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02930069 0,04255742 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02930069 0,04253213 ! sarcomere organization GO:0045214 32 22 0,000 0,02930069 0,04250688 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02930069 0,04248165 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02930069 0,04245645 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02930069 0,04243129 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02930069 0,04240615 ! gut development GO:0048565 44 22 0,000 0,02930069 0,04238104 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02930069 0,04235596 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,02930069 0,04233092 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02930069 0,0423059 ! protein stabilization GO:0050821 41 22 0,000 0,02930069 0,04228091 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,03061237 0,04414759 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,03061237 0,04412154 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,03061237 0,04409553 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,03061237 0,04406954 ! gluconeogenesis GO:0006094 38 23 0,000 0,03061237 0,04404359 ! glycerol metabolic process GO:0006071 40 23 0,000 0,03061237 0,04401767 ! viral genome replication GO:0019079 44 23 0,000 0,03061237 0,04399178 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,03061237 0,04396591 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,03061237 0,04394008 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,03061237 0,04391428 ! regeneration GO:0031099 42 23 0,000 0,03061237 0,04388851 ! axis specification GO:0009798 43 23 0,000 0,03061237 0,04386277 ! visual behavior GO:0007632 46 23 0,000 0,03061237 0,04383706 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,03061237 0,04381138 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,03061237 0,04378572 ! response to ethanol GO:0045471 47 23 0,000 0,03061237 0,0437601 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,03061237 0,04373451 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,03061237 0,04370895 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,03061237 0,04368342 ! peroxisome organization GO:0007031 43 23 0,000 0,03061237 0,04365792 ! lysosome organization GO:0007040 47 23 0,000 0,03061237 0,04363245 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,03061237 0,04360701 ! vesicle targeting GO:0006903 49 23 0,000 0,03061237 0,0435816 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,03061237 0,04355621 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,03061237 0,04353086 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,03061237 0,04350554 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,03061237 0,04348024 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,03061237 0,04345498 ! DNA modification GO:0006304 36 23 0,000 0,03061237 0,04342974 ! fatty acid transport GO:0015908 47 23 0,000 0,03061237 0,04340454 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,03061237 0,04337936 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,03061237 0,04335421 ! hormone transport GO:0009914 41 23 0,000 0,03061237 0,04332909 ! cell-cell recognition GO:0009988 28 23 0,000 0,03061237 0,04330401 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,03061237 0,04327895 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,03061237 0,04325391 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,03061237 0,04322891 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,03192232 0,0450527 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,03192232 0,04502668 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,03192232 0,0450007 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,03192232 0,04497475 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,03192232 0,04494883 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,03192232 0,04492294 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,03192232 0,04489707 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,03192232 0,04487124 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,03192232 0,04484544 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,03192232 0,04481966 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,03192232 0,04479392 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,03192232 0,04476821 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,03192232 0,04474252 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,03192232 0,04471687 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,03192232 0,04469124 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,03192232 0,04466565 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,03192232 0,04464008 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,03192232 0,04461454 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,03192232 0,04458903 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,03192232 0,04456355 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,03192232 0,0445381 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,03192232 0,04451268 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,03192232 0,04448729 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,03192232 0,04446193 ! membrane depolarization GO:0051899 45 24 0,000 0,03192232 0,04443659 ! pallium development GO:0021543 56 24 0,000 0,03192232 0,04441129 ! oogenesis GO:0048477 44 24 0,000 0,03192232 0,04438601 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,03192232 0,04436076 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,03192232 0,04433554 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,03192232 0,04431035 ! platelet activation GO:0030168 41 24 0,000 0,03192232 0,04428519 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,03192232 0,04426005 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,03192232 0,04423495 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,03192232 0,04420987 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,03192232 0,04418483 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,03192232 0,04415981 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,03192232 0,04413481 ! regulation of amine transport GO:0051952 41 24 0,000 0,03192232 0,04410985 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,03192232 0,04408492 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,03323053 0,04586564 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,03323053 0,04583974 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,03323053 0,04581387 ! leukocyte adhesion GO:0007159 55 25 0,000 0,03323053 0,04578803 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,03323053 0,04576222 ! phototransduction GO:0007602 37 25 0,000 0,03323053 0,04573644 ! keratinization GO:0031424 37 25 0,000 0,03323053 0,04571069 ! vasculogenesis GO:0001570 49 25 0,000 0,03323053 0,04568496 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,03323053 0,04565927 ! vacuole organization GO:0007033 49 25 0,000 0,03323053 0,0456336 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,03323053 0,04560797 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,03323053 0,04558236 ! receptor metabolic process GO:0043112 53 25 0,000 0,03323053 0,04555678 ! chromosome condensation GO:0030261 48 25 0,000 0,03323053 0,04553123 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,03323053 0,04550571 ! regulation of behavior GO:0050795 48 25 0,000 0,03323053 0,04548021 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,03323053 0,04545475 ! interaction with host GO:0051701 66 25 0,000 0,03323053 0,04542931 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,03323053 0,0454039 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,03323053 0,04537853 ! immunoglobulin production GO:0002377 62 25 0,000 0,03323053 0,04535317 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,03323053 0,04532785 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,03323053 0,04530256 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,03323053 0,04527729 ! liver development GO:0001889 55 25 0,000 0,03323053 0,04525205 ! protein tetramerization GO:0051262 57 25 0,000 0,03323053 0,04522684 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03453701 0,0469788 ! myelination GO:0042552 50 26 0,000 0,03453701 0,04695265 ! initiation of viral infection GO:0019059 60 26 0,000 0,03453701 0,04692654 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03453701 0,04690045 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03453701 0,0468744 ! molting cycle process GO:0022404 52 26 0,000 0,03453701 0,04684837 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03453701 0,04682237 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,03453701 0,0467964 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,03453701 0,04677046 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,03453701 0,04674455 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,03453701 0,04671867 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,03453701 0,04669282 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03453701 0,04666699 ! digestive system process GO:0022600 49 26 0,000 0,03453701 0,04664119 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03453701 0,04661542 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,03453701 0,04658968 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,03453701 0,04656397 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,03453701 0,04653829 ! neural crest cell development GO:0014032 59 26 0,000 0,03453701 0,04651263 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03453701 0,04648701 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03453701 0,04646141 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03453701 0,04643584 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03453701 0,0464103 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03453701 0,04638478 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03453701 0,0463593 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03453701 0,04633384 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,03453701 0,04630841 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,03453701 0,046283 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,03453701 0,04625763 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03453701 0,04623228 ! blastocyst development GO:0001824 50 26 0,000 0,03453701 0,04620696 ! telomere organization GO:0032200 46 26 0,000 0,03453701 0,04618167 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03453701 0,04615641 ! neural tube closure GO:0001843 58 26 0,000 0,03453701 0,04613117 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,03453701 0,04610597 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03453701 0,04608078 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03584176 0,04779554 ! embryonic pattern specification GO:0009880 49 27 0,000 0,03584176 0,04776946 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,03584176 0,04774342 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,03584176 0,0477174 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,03584176 0,04769141 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,03584176 0,04766545 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,03584176 0,04763952 ! iron ion transport GO:0006826 65 27 0,000 0,03584176 0,04761361 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,03584176 0,04758773 ! superoxide metabolic process GO:0006801 41 27 0,000 0,03584176 0,04756188 ! tube lumen formation GO:0035148 59 27 0,000 0,03584176 0,04753606 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,03584176 0,04751027 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,03584176 0,04748451 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,03584176 0,04745877 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,03584176 0,04743306 ! response to starvation GO:0042594 47 27 0,000 0,03584176 0,04740738 ! response to toxin GO:0009636 49 27 0,000 0,03584176 0,04738173 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,03584176 0,0473561 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,03584176 0,0473305 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,03584176 0,04730493 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,03584176 0,04727939 ! leukocyte proliferation GO:0070661 59 27 0,000 0,03584176 0,04725387 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,03584176 0,04722839 ! neuron fate commitment GO:0048663 52 28 0,000 0,03714479 0,04891899 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,03714479 0,04889263 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,03714479 0,0488663 ! protein amino acid acylation GO:0043543 59 28 0,000 0,03714479 0,04884 ! vesicle docking GO:0048278 55 28 0,000 0,03714479 0,04881373 ! circadian rhythm GO:0007623 56 28 0,000 0,03714479 0,04878749 ! dendrite development GO:0016358 67 28 0,000 0,03714479 0,04876127 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,03714479 0,04873508 ! fat cell differentiation GO:0045444 57 28 0,000 0,03714479 0,04870892 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03714479 0,04868279 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03714479 0,04865669 ! base-excision repair GO:0006284 41 28 0,000 0,03714479 0,04863061 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03714479 0,04860457 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03714479 0,04857855 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03714479 0,04855255 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03714479 0,04852659 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,03714479 0,04850065 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03714479 0,04847475 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03714479 0,04844886 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03714479 0,04842301 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03714479 0,04839719 ! lipid oxidation GO:0034440 48 28 0,000 0,03714479 0,04837139 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,03714479 0,04834562 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03714479 0,04831987 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,03844609 0,04998606 ! translational initiation GO:0006413 66 29 0,000 0,03844609 0,04995947 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03844609 0,04993291 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03844609 0,04990638 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03844609 0,04987987 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,03844609 0,0498534 ! autophagy GO:0006914 47 29 0,000 0,03844609 0,04982695 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03844609 0,04980053 ! primary neural tube formation GO:0014020 61 29 0,000 0,03844609 0,04977414 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03844609 0,04974778 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03844609 0,04972144 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03844609 0,04969513 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,03844609 0,04966885 ! somitogenesis GO:0001756 52 29 0,000 0,03844609 0,0496426 ! synaptogenesis GO:0007416 46 29 0,000 0,03844609 0,04961638 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,03844609 0,04959018 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03844609 0,04956401 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03844609 0,04953787 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,03844609 0,04951176 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,03974567 0,05115842 ! phenol metabolic process GO:0018958 56 30 0,000 0,03974567 0,05113148 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03974567 0,05110457 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03974567 0,05107768 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03974567 0,05105083 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03974567 0,051024 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03974567 0,05099721 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03974567 0,05097043 ! acute-phase response GO:0006953 50 30 0,000 0,03974567 0,05094369 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03974567 0,05091698 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03974567 0,05089029 ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,03974567 0,05086363 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,03974567 0,050837 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03974567 0,0508104 ! cell fate determination GO:0001709 64 30 0,000 0,03974567 0,05078383 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03974567 0,05075728 ! phospholipid transport GO:0015914 65 30 0,000 0,03974567 0,05073076 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03974567 0,05070427 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03974567 0,05067781 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03974567 0,05065137 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03974567 0,05062496 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,03974567 0,05059858 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,04104353 0,05222362 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,04104353 0,05219643 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,04104353 0,05216928 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,04104353 0,05214215 ! cell junction assembly GO:0034329 85 31 0,000 0,04104353 0,05211505 ! regulation of innate immune response GO:0045088 57 31 0,000 0,04104353 0,05208797 ! ovulation cycle process GO:0022602 55 31 0,000 0,04104353 0,05206093 ! peptide transport GO:0015833 60 31 0,000 0,04104353 0,05203391 ! male gonad development GO:0008584 56 31 0,000 0,04104353 0,05200692 ! iron ion homeostasis GO:0055072 60 31 0,000 0,04104353 0,05197996 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,04104353 0,05195303 ! detection of light stimulus GO:0009583 44 31 0,000 0,04104353 0,05192613 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,04104353 0,05189925 ! natural killer cell activation GO:0030101 50 31 0,000 0,04104353 0,0518724 ! ensheathment of neurons GO:0007272 64 31 0,000 0,04104353 0,05184558 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,04104353 0,05181879 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,04104353 0,05179202 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,04104353 0,05176528 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,04104353 0,05173857 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,04233968 0,05334493 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,04233968 0,05331744 ! collagen metabolic process GO:0032963 49 32 0,000 0,04233968 0,05328997 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,04233968 0,05326253 ! spindle organization GO:0007051 50 32 0,000 0,04233968 0,05323511 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,04233968 0,05320773 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,04233968 0,05318037 ! metanephros development GO:0001656 81 32 0,000 0,04233968 0,05315305 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,04233968 0,05312575 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,04233968 0,05309847 ! mesoderm formation GO:0001707 73 32 0,000 0,04233968 0,05307123 ! ovulation cycle GO:0042698 57 32 0,000 0,04233968 0,05304401 ! peripheral nervous system development GO:0007422 68 32 0,000 0,04233968 0,05301683 ! BMP signaling pathway GO:0030509 71 32 0,000 0,04233968 0,05298967 ! hindbrain development GO:0030902 65 32 0,000 0,04233968 0,05296253 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,04233968 0,05293543 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,04233968 0,05290835 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,04233968 0,0528813 ! gene silencing GO:0016458 71 32 0,000 0,04233968 0,05285428 ! regulation of pH GO:0006885 56 33 0,000 0,0436341 0,05444235 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,0436341 0,05441455 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,0436341 0,05438679 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,0436341 0,05435906 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,0436341 0,05433135 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,0436341 0,05430367 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,0436341 0,05427602 ! response to ionizing radiation GO:0010212 74 33 0,000 0,0436341 0,0542484 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,0436341 0,05422081 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,0436341 0,05419324 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,0436341 0,05416571 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,0436341 0,0541382 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,0436341 0,05411072 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,0436341 0,05408326 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,0436341 0,05405584 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,04492682 0,0556291 ! glial cell differentiation GO:0010001 67 34 0,000 0,04492682 0,05560092 ! post-embryonic development GO:0009791 76 34 0,000 0,04492682 0,05557277 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,04492682 0,05554464 ! cholesterol transport GO:0030301 62 34 0,000 0,04492682 0,05551655 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,04492682 0,05548848 ! spliceosome assembly GO:0000245 75 34 0,000 0,04492682 0,05546044 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,04492682 0,05543243 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,04492682 0,05540445 ! formation of primary germ layer GO:0001704 76 34 0,000 0,04492682 0,05537649 ! cell fate specification GO:0001708 56 34 0,000 0,04492682 0,05534857 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,04492682 0,05532067 ! adult locomotory behavior GO:0008344 62 34 0,000 0,04492682 0,0552928 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,04492682 0,05526496 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,04621782 0,05682443 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,04621782 0,05679584 ! negative regulation of secretion GO:0051048 68 35 0,000 0,04621782 0,05676729 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,04621782 0,05673876 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,04621782 0,05671026 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,04621782 0,05668179 ! membrane docking GO:0022406 69 35 0,000 0,04621782 0,05665335 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,04621782 0,05662494 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,04621782 0,05659656 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,04621782 0,0565682 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,04621782 0,05653988 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,04621782 0,05651158 ! ceramide metabolic process GO:0006672 72 35 0,000 0,04621782 0,05648331 ! telencephalon development GO:0021537 81 35 0,000 0,04621782 0,05645507 ! sterol transport GO:0015918 63 35 0,000 0,04621782 0,05642685 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,04621782 0,05639867 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,04621782 0,05637051 ! placenta development GO:0001890 53 35 0,000 0,04621782 0,05634238 ! vesicle localization GO:0051648 70 35 0,000 0,04621782 0,05631428 ! regulation of muscle development GO:0048634 82 36 0,000 0,04750711 0,05785637 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,04750711 0,05782754 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,04750711 0,05779874 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,04750711 0,05776997 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,04750711 0,05774123 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,04750711 0,05771252 ! positive regulation of cell development GO:0010720 85 36 0,000 0,04750711 0,05768384 ! regulation of proteolysis GO:0030162 77 36 0,000 0,04750711 0,05765518 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,04750711 0,05762655 ! aerobic respiration GO:0009060 56 36 0,000 0,04750711 0,05759795 ! cytokine production GO:0001816 68 36 0,000 0,04750711 0,05756938 ! embryonic organ development GO:0048568 67 36 0,000 0,04750711 0,05754084 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,04750711 0,05751233 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,0487947 0,05904183 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,0487947 0,0590126 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,0487947 0,0589834 ! sister chromatid segregation GO:0000819 65 37 0,000 0,0487947 0,05895423 ! odontogenesis GO:0042476 74 37 0,000 0,0487947 0,05892509 ! tissue remodeling GO:0048771 78 37 0,000 0,0487947 0,05889598 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,0487947 0,05886689 ! female gonad development GO:0008585 71 37 0,000 0,0487947 0,05883784 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,0487947 0,05880881 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,0487947 0,05877981 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,0487947 0,05875084 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,0487947 0,0587219 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,05008058 0,06023972 ! meiosis I GO:0007127 74 38 0,000 0,05008058 0,06021007 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,05008058 0,06018046 ! organic anion transport GO:0015711 82 38 0,000 0,05008058 0,06015087 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,05008058 0,06012131 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,05008058 0,06009178 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,05008058 0,06006228 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,05008058 0,06003281 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,05008058 0,06000337 ! regulation of protein stability GO:0031647 77 38 0,000 0,05008058 0,05997395 ! spermatid development GO:0007286 69 38 0,000 0,05008058 0,05994457 ! glycogen metabolic process GO:0005977 63 38 0,000 0,05008058 0,05991521 ! pigment metabolic process GO:0042440 87 38 0,000 0,05008058 0,05988589 ! neural tube formation GO:0001841 79 38 0,000 0,05008058 0,05985659 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,05136477 0,06136143 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,05136477 0,06133144 ! negative regulation of binding GO:0051100 71 39 0,000 0,05136477 0,06130148 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,05136477 0,06127154 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,05136477 0,06124164 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,05136477 0,06121177 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,05136477 0,06118192 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,05136477 0,06115211 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,05136477 0,06112232 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,05136477 0,06109256 ! glucan metabolic process GO:0044042 64 39 0,000 0,05136477 0,06106283 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,05264725 0,06255702 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,05264725 0,0625266 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,05264725 0,06249622 ! learning GO:0007612 82 40 0,000 0,05264725 0,06246587 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,05264725 0,06243555 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,05264725 0,06240525 ! lipid homeostasis GO:0055088 75 40 0,000 0,05264725 0,06237499 ! mismatch repair GO:0006298 58 40 0,000 0,05264725 0,06234475 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,05264725 0,06231455 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,05264725 0,06228437 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,05264725 0,06225422 ! RNA export from nucleus GO:0006405 61 41 0,000 0,05392803 0,06373787 ! mRNA catabolic process GO:0006402 79 41 0,000 0,05392803 0,06370705 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,05392803 0,06367626 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,05392803 0,0636455 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,05392803 0,06361476 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,05392803 0,06358406 ! gliogenesis GO:0042063 91 41 0,000 0,05392803 0,06355339 ! feeding behavior GO:0007631 69 41 0,000 0,05392803 0,06352275 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,05392803 0,06349213 ! mesenchymal cell development GO:0014031 94 41 0,000 0,05392803 0,06346155 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,05392803 0,063431 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,05392803 0,06340047 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,05392803 0,06336997 ! spermatid differentiation GO:0048515 73 41 0,000 0,05392803 0,06333951 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,05392803 0,06330907 ! RNA modification GO:0009451 64 41 0,000 0,05392803 0,06327866 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,05520712 0,06474843 ! ear morphogenesis GO:0042471 64 42 0,000 0,05520712 0,06471736 ! organic ether metabolic process GO:0018904 59 42 0,000 0,05520712 0,06468633 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,05520712 0,06465532 ! T cell differentiation GO:0030217 93 42 0,000 0,05520712 0,06462434 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,05520712 0,06459339 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,05520712 0,06456246 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,05520712 0,06453157 ! regulation of protein secretion GO:0050708 77 42 0,000 0,05520712 0,06450071 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,05520712 0,06446988 ! cytokinesis GO:0000910 84 42 0,000 0,05520712 0,06443908 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,05520712 0,0644083 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,05648451 0,06586714 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,05648451 0,06583572 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,05648451 0,06580432 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,05648451 0,06577296 ! regulation of tube size GO:0035150 76 43 0,000 0,05648451 0,06574162 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,05648451 0,06571032 ! glucose transport GO:0015758 66 43 0,000 0,05648451 0,06567904 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,05648451 0,06564779 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,05648451 0,06561658 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,05648451 0,06558539 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,05648451 0,06555423 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,05648451 0,06552311 ! segmentation GO:0035282 78 43 0,000 0,05648451 0,06549201 ! ion transmembrane transport GO:0034220 79 43 0,000 0,05648451 0,06546094 ! neuron migration GO:0001764 85 43 0,000 0,05648451 0,0654299 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,05648451 0,06539889 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,05776022 0,06684425 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,05776022 0,0668126 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,05776022 0,06678098 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,05776022 0,06674939 ! hexose transport GO:0008645 68 44 0,000 0,05776022 0,06671783 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,05776022 0,0666863 ! striated muscle contraction GO:0006941 85 44 0,000 0,05776022 0,0666548 ! phagocytosis GO:0006909 105 44 0,000 0,05776022 0,06662333 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,05776022 0,06659189 ! double-strand break repair GO:0006302 85 44 0,000 0,05776022 0,06656047 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,05903423 0,06799652 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,05903423 0,06796448 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,05903423 0,06793246 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,05903423 0,06790048 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,05903423 0,06786853 ! biopolymer methylation GO:0043414 91 45 0,000 0,05903423 0,06783661 ! B cell differentiation GO:0030183 124 45 0,000 0,05903423 0,06780471 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,05903423 0,06777285 ! female gamete generation GO:0007292 71 45 0,000 0,05903423 0,06774102 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,05903423 0,06770921 ! developmental growth GO:0048589 88 45 0,000 0,05903423 0,06767744 ! maintenance of location in cell GO:0051651 101 45 0,000 0,05903423 0,0676457 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,06030656 0,06907122 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,06030656 0,06903886 ! glycolysis GO:0006096 71 46 0,000 0,06030656 0,06900652 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,06030656 0,06897421 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,06030656 0,06894194 ! leukocyte migration GO:0050900 75 46 0,000 0,06030656 0,06890969 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,06030656 0,06887748 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,06030656 0,06884529 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,06030656 0,06881313 ! pigmentation GO:0043473 103 46 0,000 0,06030656 0,06878101 ! cell growth GO:0016049 90 46 0,000 0,06030656 0,06874891 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,06030656 0,06871685 ! neural tube development GO:0021915 91 47 0,000 0,0615772 0,07013198 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,0615772 0,0700993 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,06284616 0,07151056 ! positive regulation of defense response GO:0031349 88 48 0,000 0,06284616 0,07147727 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,06284616 0,07144401 ! mitochondrial transport GO:0006839 94 48 0,000 0,06284616 0,07141078 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,06284616 0,07137758 ! cellular component disassembly GO:0022411 89 48 0,000 0,06284616 0,07134441 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,06284616 0,07131127 ! endosome transport GO:0016197 127 48 0,000 0,06284616 0,07127817 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,06284616 0,07124509 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,06284616 0,07121205 ! male sex differentiation GO:0046661 93 48 0,000 0,06284616 0,07117903 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,06284616 0,07114605 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,06284616 0,07111309 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,06284616 0,07108017 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,06284616 0,07104728 ! methylation GO:0032259 97 48 0,000 0,06284616 0,07101442 ! response to calcium ion GO:0051592 94 49 0,000 0,06411344 0,07241292 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,06411344 0,07237945 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,06411344 0,07234602 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,06411344 0,07231262 ! JNK cascade GO:0007254 106 49 0,000 0,06411344 0,07227925 ! protein homooligomerization GO:0051260 84 49 0,000 0,06411344 0,07224591 ! regulation of action potential GO:0001508 102 50 0,000 0,06537904 0,07363808 ! regulation of ion transport GO:0043269 86 50 0,000 0,06537904 0,07360415 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,06537904 0,07357025 ! endocrine system development GO:0035270 109 50 0,000 0,06537904 0,07353637 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,06537904 0,07350253 ! activation of caspase activity GO:0006919 95 50 0,000 0,06537904 0,07346872 ! regulation of ossification GO:0030278 123 50 0,000 0,06537904 0,07343494 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,06537904 0,0734012 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,06537904 0,07336748 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,06537904 0,07333379 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,06537904 0,07330014 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,06537904 0,07326652 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,06664297 0,07464868 ! viral infectious cycle GO:0019058 104 51 0,000 0,06664297 0,07461447 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,06664297 0,07458029 ! peptide metabolic process GO:0006518 80 51 0,000 0,06664297 0,07454614 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,06664297 0,07451203 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,06664297 0,07447794 ! positive regulation of binding GO:0051099 88 52 0,000 0,06790522 0,07585389 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,06790522 0,07581922 ! Notch signaling pathway GO:0007219 111 52 0,000 0,06790522 0,07578459 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,06790522 0,07574998 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,06790522 0,07571541 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,06790522 0,07568087 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,06790522 0,07564636 ! excretion GO:0007588 87 52 0,000 0,06790522 0,07561188 ! histone modification GO:0016570 104 52 0,000 0,06790522 0,07557743 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,06790522 0,07554301 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,06790522 0,07550863 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,06790522 0,07547428 ! amino acid activation GO:0043038 98 52 0,000 0,06790522 0,07543995 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,0691658 0,07680548 ! positive regulation of growth GO:0045927 96 53 0,000 0,0691658 0,07677059 ! inner ear development GO:0048839 89 53 0,000 0,0691658 0,07673572 ! chromatin remodeling GO:0006338 122 53 0,000 0,0691658 0,07670089 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,0691658 0,07666609 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,0691658 0,07663132 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,0691658 0,07659658 ! cartilage development GO:0051216 99 53 0,000 0,0691658 0,07656188 ! synapse organization GO:0050808 102 53 0,000 0,0691658 0,0765272 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,07042472 0,07788483 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,07042472 0,07784958 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,07042472 0,07781437 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,07042472 0,0777792 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,07042472 0,07774405 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,07042472 0,07770893 ! membrane fusion GO:0006944 122 54 0,000 0,07042472 0,07767385 ! covalent chromatin modification GO:0016569 115 54 0,000 0,07042472 0,0776388 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,07042472 0,07760378 ! regulation of cell shape GO:0008360 142 54 0,000 0,07042472 0,07756879 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,07042472 0,07753384 ! RNA catabolic process GO:0006401 103 55 0,000 0,07168196 0,07888245 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,07168196 0,07884693 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,07168196 0,07881144 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,07168196 0,07877599 ! cell recognition GO:0008037 98 55 0,000 0,07168196 0,07874057 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,07168196 0,07870518 ! cell maturation GO:0048469 107 55 0,000 0,07168196 0,07866982 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,07168196 0,0786345 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,07168196 0,07859921 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,07293754 0,07994007 ! glucose catabolic process GO:0006007 88 56 0,000 0,07293754 0,07990422 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,07293754 0,0798684 ! regulation of DNA replication GO:0006275 105 56 0,000 0,07293754 0,07983262 ! RNA elongation GO:0006354 90 56 0,000 0,07293754 0,07979687 ! chloride transport GO:0006821 102 57 0,000 0,07419146 0,08113238 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,07419146 0,08109608 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,07419146 0,08105981 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,07419146 0,08102357 ! heart morphogenesis GO:0003007 105 57 0,000 0,07419146 0,08098737 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,07419146 0,0809512 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,07419146 0,08091506 ! regulation of actin filament length GO:0030832 118 58 0,000 0,07544371 0,08224408 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,07544371 0,0822074 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,07544371 0,08217075 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,07544371 0,08213413 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,07544371 0,08209755 ! aging GO:0007568 112 58 0,000 0,07544371 0,08206099 ! gastrulation GO:0007369 122 58 0,000 0,07544371 0,08202447 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,07544371 0,08198799 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,07544371 0,08195153 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,07544371 0,08191511 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,07544371 0,08187872 ! maintenance of location GO:0051235 124 58 0,000 0,07544371 0,08184236 ! nuclear export GO:0051168 110 59 0,000 0,07669431 0,0831621 ! establishment of organelle localization GO:0051656 122 59 0,000 0,07669431 0,0831252 ! lipid modification GO:0030258 112 60 0,000 0,07794325 0,0844414 ! DNA catabolic process GO:0006308 94 60 0,000 0,07794325 0,08440397 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,07794325 0,08436658 ! adult behavior GO:0030534 104 60 0,000 0,07794325 0,08432921 ! kidney development GO:0001822 133 60 0,000 0,07794325 0,08429188 ! positive regulation of secretion GO:0051047 110 61 0,000 0,07919054 0,08560287 ! regulation of cellular component size GO:0032535 125 61 0,000 0,07919054 0,08556501 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,07919054 0,08552718 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,07919054 0,08548939 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,07919054 0,08545163 ! regulation of heart contraction GO:0008016 123 61 0,000 0,07919054 0,0854139 ! camera-type eye development GO:0043010 126 61 0,000 0,07919054 0,08537621 ! proton transport GO:0015992 117 61 0,000 0,07919054 0,08533855 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,07919054 0,08530092 ! viral reproductive process GO:0022415 132 62 0,000 0,08043617 0,08660448 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,08043617 0,08656633 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,08043617 0,08652821 ! tRNA processing GO:0008033 102 62 0,000 0,08043617 0,08649013 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,08043617 0,08645208 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,08168016 0,08775049 ! mesoderm development GO:0007498 128 63 0,000 0,08168016 0,08771192 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,08168016 0,08767339 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,08168016 0,08763488 ! hydrogen transport GO:0006818 121 64 0,000 0,08292249 0,08892873 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,08292249 0,08888971 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,08292249 0,08885073 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,08292249 0,08881177 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,08416319 0,09010108 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,08416319 0,09006161 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,08416319 0,09002218 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,08416319 0,08998278 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,08416319 0,08994342 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,08416319 0,08990409 ! ear development GO:0043583 114 66 0,000 0,08540223 0,09118779 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,08540223 0,09114795 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,08540223 0,09110815 ! gonad development GO:0008406 115 66 0,000 0,08540223 0,09106838 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,08540223 0,09102865 ! activation of MAPK activity GO:0000187 124 67 0,000 0,08663964 0,0923073 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,08663964 0,09226706 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,08663964 0,09222686 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,08663964 0,09218669 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,08663964 0,09214656 ! secondary metabolic process GO:0019748 125 67 0,000 0,08663964 0,09210646 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,08663964 0,09206639 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,08787541 0,09333896 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,08787541 0,0932984 ! hexose catabolic process GO:0019320 113 68 0,000 0,08787541 0,09325787 ! extracellular matrix organization GO:0030198 146 68 0,000 0,08787541 0,09321738 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,08787541 0,09317692 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,08787541 0,09313649 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,08787541 0,0930961 ! viral reproduction GO:0016032 142 68 0,000 0,08787541 0,09305575 ! regulation of lipase activity GO:0060191 137 68 0,000 0,08787541 0,09301543 ! adaptive immune response GO:0002250 126 68 0,000 0,08787541 0,09297515 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,08910954 0,09424008 ! lung development GO:0030324 165 69 0,000 0,08910954 0,09419931 ! urogenital system development GO:0001655 149 69 0,000 0,08910954 0,09415856 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,08910954 0,09411785 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,08910954 0,09407718 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,08910954 0,09403654 ! developmental maturation GO:0021700 128 69 0,000 0,08910954 0,09399594 ! single fertilization GO:0007338 83 69 0,000 0,08910954 0,09395537 ! cell redox homeostasis GO:0045454 114 70 0,000 0,09034203 0,0952138 ! germ cell development GO:0007281 133 70 0,000 0,09034203 0,09517274 ! activation of immune response GO:0002253 120 70 0,000 0,09034203 0,09513172 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,09034203 0,09509073 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,09157289 0,09634478 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,09157289 0,0963033 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,09157289 0,09626186 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,09157289 0,09622046 ! appendage morphogenesis GO:0035107 150 72 0,000 0,09280212 0,09747016 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,09280212 0,09742827 ! respiratory tube development GO:0030323 171 72 0,000 0,09280212 0,09738642 ! B cell activation GO:0042113 179 72 0,000 0,09280212 0,0973446 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,09280212 0,09730283 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,09280212 0,09726108 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,09280212 0,09721938 ! appendage development GO:0048736 151 73 0,000 0,09402972 0,09846319 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,09402972 0,098421 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,09402972 0,09837885 ! regulation of immune effector process GO:0002697 156 73 0,000 0,09402972 0,09833674 ! acute inflammatory response GO:0002526 118 74 0,000 0,0952557 0,09957624 ! amino acid transport GO:0006865 148 74 0,000 0,0952557 0,09953365 ! regulation of caspase activity GO:0043281 136 74 0,000 0,0952557 0,0994911 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,0952557 0,09944858 ! respiratory system development GO:0060541 175 74 0,000 0,0952557 0,0994061 ! organelle localization GO:0051640 155 74 0,000 0,0952557 0,09936365 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,09648005 0,10059785 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,09648005 0,10055493 ! reproductive structure development GO:0048608 131 75 0,000 0,09648005 0,10051205 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,09648005 0,10046921 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,09648005 0,1004264 ! axon guidance GO:0007411 162 75 0,000 0,09648005 0,10038363 ! rhythmic process GO:0048511 142 75 0,000 0,09648005 0,1003409 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,09770278 0,10156931 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,09770278 0,10152611 ! learning or memory GO:0007611 161 76 0,000 0,09770278 0,10148295 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,09770278 0,10143982 ! regulation of blood pressure GO:0008217 134 76 0,000 0,09770278 0,10139672 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,09770278 0,10135367 ! amine catabolic process GO:0009310 136 77 0,000 0,09892389 0,10257685 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,09892389 0,10253333 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,09892389 0,10248985 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,09892389 0,1024464 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,09892389 0,10240299 ! regulation of catabolic process GO:0009894 173 77 0,000 0,09892389 0,10235962 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,10014338 0,10357759 ! antigen processing and presentation GO:0019882 117 78 0,000 0,10014338 0,10353376 ! fertilization GO:0009566 99 78 0,000 0,10014338 0,10348996 ! blood coagulation GO:0007596 151 79 0,000 0,10136125 0,10470424 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,10136125 0,10465999 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,10136125 0,10461577 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,10136125 0,10457159 ! protein oligomerization GO:0051259 149 79 0,000 0,10136125 0,10452745 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,10136125 0,10448335 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,10257751 0,10569248 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,10257751 0,10564792 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,10257751 0,1056034 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,10257751 0,10555891 ! meiosis GO:0007126 143 81 0,000 0,10379216 0,10676389 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 0,000 0,10379216 0,10671896 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,10379216 0,10667406 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,10379216 0,1066292 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,1050052 0,10783005 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,1050052 0,10778475 ! protein import into nucleus GO:0006606 174 82 0,000 0,1050052 0,10773948 ! meiotic cell cycle GO:0051321 144 82 0,000 0,1050052 0,10769425 ! response to drug GO:0042493 149 83 0,000 0,10621663 0,10889099 ! response to oxygen levels GO:0070482 183 83 0,000 0,10621663 0,10884531 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,10621663 0,10879967 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,10621663 0,10875407 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,10621663 0,10870851 ! nuclear import GO:0051170 177 83 0,000 0,10621663 0,10866299 ! inorganic anion transport GO:0015698 156 83 0,000 0,10621663 0,10861751 ! response to metal ion GO:0010038 158 84 0,000 0,10742645 0,10980871 ! T cell activation GO:0042110 189 84 0,000 0,10742645 0,10976279 ! response to nutrient GO:0007584 135 84 0,000 0,10742645 0,1097169 ! digestion GO:0007586 130 84 0,000 0,10742645 0,10967105 ! hemostasis GO:0007599 165 85 0,000 0,10863467 0,11085819 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,10863467 0,1108119 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,10863467 0,11076566 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,10863467 0,11071945 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,11104631 0,11313017 ! mitochondrion organization GO:0007005 159 87 0,000 0,11104631 0,11308301 ! nucleosome assembly GO:0006334 126 87 0,000 0,11104631 0,11303589 ! regulation of protein transport GO:0051223 165 87 0,000 0,11104631 0,11298882 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,11224974 0,11416574 ! amine biosynthetic process GO:0009309 146 88 0,000 0,11224974 0,11411823 ! sensory perception of smell GO:0007608 117 88 0,000 0,11224974 0,11407076 ! chromatin assembly GO:0031497 128 88 0,000 0,11224974 0,11402333 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,11224974 0,11397594 ! regulation of DNA binding GO:0051101 167 89 0,000 0,11345157 0,11514839 ! tube morphogenesis GO:0035239 194 89 0,000 0,11345157 0,11510057 ! cellular defense response GO:0006968 123 89 0,000 0,11345157 0,11505279 ! protein localization in nucleus GO:0034504 192 89 0,000 0,11345157 0,11500505 ! regulation of neurological system process GO:0031644 175 89 0,000 0,11345157 0,11495735 ! response to inorganic substance GO:0010035 173 90 0,000 0,1146518 0,11612535 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,1146518 0,11607723 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,1146518 0,11602914 ! gland development GO:0048732 220 91 0,000 0,11585044 0,11719364 ! defense response to bacterium GO:0042742 112 91 0,000 0,11585044 0,11714513 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,1170475 0,1183066 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,1170475 0,11825767 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,11824297 0,11941611 ! amine transport GO:0015837 181 93 0,000 0,11824297 0,11936676 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,11824297 0,11931746 ! vitamin metabolic process GO:0006766 153 93 0,000 0,11824297 0,11926819 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,11943685 0,12042271 ! female pregnancy GO:0007565 166 94 0,000 0,11943685 0,12037303 ! sterol metabolic process GO:0016125 166 94 0,000 0,11943685 0,12032339 ! regulation of membrane potential GO:0042391 179 94 0,000 0,11943685 0,12027379 ! regulation of defense response GO:0031347 171 95 0,000 0,12062915 0,1214244 ! nucleosome organization GO:0034728 143 95 0,000 0,12062915 0,12137439 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,12062915 0,12132442 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,12062915 0,12127449 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,12062915 0,1212246 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,12062915 0,12117476 ! sex differentiation GO:0007548 171 96 0,000 0,12181987 0,12232057 ! regulation of T cell activation GO:0050863 175 96 0,000 0,12181987 0,12227031 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,12300901 0,12341315 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,12300901 0,12336248 ! transcription initiation GO:0006352 171 97 0,000 0,12300901 0,12331186 ! regulation of protein localization GO:0032880 188 97 0,000 0,12300901 0,12326128 ! leukocyte differentiation GO:0002521 232 98 0,000 0,12419657 0,12440026 ! forebrain development GO:0030900 210 98 0,000 0,12419657 0,12434927 ! mRNA transport GO:0051028 185 100 0,000 0,12656698 0,12667068 ! positive regulation of immune response GO:0050778 175 100 0,000 0,12656698 0,12661881 ! hormone metabolic process GO:0042445 171 100 0,000 0,12656698 0,12656698