pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/6227-7-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! translational initiation GO:0006413 48 28 3,000 3,895E-08 9,242E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 3,000 5,454E-07 6,471E-04 ! gene silencing by RNA GO:0031047 22 14 2,000 6,329E-07 5,006E-04 ! nuclear export GO:0051168 85 57 3,000 7,332E-07 4,35E-04 ! protein export from nucleus GO:0006611 26 17 2,000 1,179E-06 5,597E-04 ! negative regulation of translation GO:0017148 28 20 2,000 1,972E-06 7,8E-04 ! gene silencing GO:0016458 47 28 2,000 5,63E-06 1,909E-03 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 1,514E-05 4,489E-03 ! positive regulation of viral genome replication GO:0045070 8 5 1,000 1,514E-05 3,991E-03 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 1,000 1,514E-05 3,592E-03 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 1,000 1,514E-05 3,265E-03 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 2,000 2,246E-05 4,442E-03 ! positive regulation of Rho GTPase activity GO:0032321 12 6 1,000 2,269E-05 4,141E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,173E-05 5,379E-03 ! negative regulation of translational initiation GO:0045947 9 7 1,000 3,173E-05 5,02E-03 ! DNA topological change GO:0006265 10 7 1,000 3,173E-05 4,707E-03 ! keratinocyte proliferation GO:0043616 15 8 1,000 4,228E-05 5,902E-03 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 1,000 4,228E-05 5,574E-03 GO:0030204|chondroitin sulfate metabolic process, ! regulation of focal adhesion formation GO:0051893 17 8 1,000 4,228E-05 5,281E-03 ! regulation of stress fiber formation GO:0051492 24 10 1,000 6,785E-05 8,05E-03 ! DNA ligation GO:0006266 16 10 1,000 6,785E-05 7,667E-03 ! positive regulation of viral reproduction GO:0048524 14 10 1,000 6,785E-05 7,318E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 1,000 6,785E-05 7E-03 ! positive regulation of Ras GTPase activity GO:0032320 24 10 1,000 6,785E-05 6,708E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 2,000 7,62E-05 7,233E-03 ! regulation of phosphatase activity GO:0010921 23 11 1,000 8,286E-05 7,562E-03 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 1,000 8,286E-05 7,282E-03 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of actin filament bundle formation GO:0032231 25 11 1,000 8,286E-05 7,022E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 2,000 9,085E-05 7,434E-03 ! positive regulation of GTPase activity GO:0043547 29 12 1,000 9,935E-05 7,859E-03 ! regulation of Rho GTPase activity GO:0032319 22 12 1,000 9,935E-05 7,605E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 2,000 1,03E-04 7,636E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 2,000 1,03E-04 7,404E-03 ! positive regulation of ligase activity GO:0051351 114 76 2,000 1,161E-04 8,103E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 2,000 1,303E-04 8,832E-03 ! regulation of protein ubiquitination GO:0031396 20 14 1,000 1,368E-04 9,016E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,368E-04 8,772E-03 ! regulation of ligase activity GO:0051340 129 82 2,000 1,455E-04 9,088E-03 ! skin development GO:0043588 28 15 1,000 1,577E-04 9,595E-03 ! release of cytochrome c from mitochondria GO:0001836 29 15 1,000 1,577E-04 9,355E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 2,000 1,619E-04 9,371E-03 GO:0010498|proteasomal protein catabolic process, ! interphase of mitotic cell cycle GO:0051329 166 87 2,000 1,735E-04 9,8E-03 ! positive regulation of cell growth GO:0030307 22 16 1,000 1,801E-04 9,938E-03 ! interphase GO:0051325 169 89 2,000 1,855E-04 0,0100063 ! negative regulation of peptidase activity GO:0010466 25 17 1,000 2,039E-04 0,01075455 ! regulation of viral genome replication GO:0045069 26 17 1,000 2,039E-04 0,01052075 ! cellular response to unfolded protein GO:0034620 24 18 1,000 2,293E-04 0,0115751 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 38 18 1,000 2,293E-04 0,01133395 ! positive regulation of cell size GO:0045793 26 19 1,000 2,56E-04 0,01239928 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 1,000 2,56E-04 0,01215129 ! aminoglycan biosynthetic process GO:0006023 28 20 1,000 2,843E-04 0,01322651 ! chromosome condensation GO:0030261 32 20 1,000 2,843E-04 0,01297215 ! apoptotic mitochondrial changes GO:0008637 42 21 1,000 3,139E-04 0,01405628 ! apoptotic nuclear changes GO:0030262 31 21 1,000 3,139E-04 0,01379598 ! proteoglycan biosynthetic process GO:0030166 33 22 1,000 3,451E-04 0,01488818 ! regulation of viral reproduction GO:0050792 33 23 1,000 3,776E-04 0,01600259 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 1,000 4,117E-04 0,01713789 ! response to endoplasmic reticulum stress GO:0034976 32 24 1,000 4,117E-04 0,01684241 ! regulation of cell-matrix adhesion GO:0001952 57 25 1,000 4,471E-04 0,01798282 GO:0010810|regulation of cell-substrate adhesion, ! ER-nuclear signaling pathway GO:0006984 33 26 1,000 4,84E-04 0,01914195 ! proteoglycan metabolic process GO:0006029 42 27 1,000 5,223E-04 0,02031875 ! fat cell differentiation GO:0045444 41 27 1,000 5,223E-04 0,01999102 ! negative regulation of protein modification process GO:0031400 56 28 1,000 5,621E-04 0,02117076 ! positive regulation of cell adhesion GO:0045785 54 29 1,000 6,032E-04 0,02236643 ! negative regulation of hydrolase activity GO:0051346 56 35 1,000 8,8E-04 0,03212534 ! nucleus organization GO:0006997 58 37 1,000 9,834E-04 0,03535947 ! keratinocyte differentiation GO:0030216 55 37 1,000 9,834E-04 0,03483172 ! polysaccharide biosynthetic process GO:0000271 51 39 1,000 1,093E-03 0,03812556 ! RNA export from nucleus GO:0006405 57 41 1,000 1,207E-03 0,04151482 ! induction of apoptosis by intracellular signals GO:0008629 78 42 1,000 1,267E-03 0,04293478 ! epidermal cell differentiation GO:0009913 61 42 1,000 1,267E-03 0,04233007 ! response to calcium ion GO:0051592 65 43 1,000 1,327E-03 0,04374468 ! positive regulation of cell cycle GO:0045787 83 45 1,000 1,453E-03 0,04722957 ! glycosaminoglycan metabolic process GO:0030203 68 45 1,000 1,453E-03 0,04659133 ! response to insulin stimulus GO:0032868 71 45 1,000 1,453E-03 0,04597011 ! regulation of translational initiation GO:0006446 70 46 1,000 1,518E-03 0,04739082 ! response to UV GO:0009411 79 47 1,000 1,584E-03 0,04881669 ! aminoglycan metabolic process GO:0006022 77 52 1,000 1,936E-03 0,05888599 ! sulfur compound biosynthetic process GO:0044272 71 53 1,000 2,01E-03 0,06037417 ! positive regulation of growth GO:0045927 78 58 1,000 2,402E-03 0,07124301 ! DNA damage response, signal transduction GO:0042770 105 58 1,000 2,402E-03 0,07036346 ! chromosome segregation GO:0007059 93 59 1,000 2,484E-03 0,07188887 ! response to peptide hormone stimulus GO:0043434 97 60 1,000 2,568E-03 0,07341534 ! negative regulation of protein kinase activity GO:0006469 110 62 1,000 2,739E-03 0,07738133 ! negative regulation of kinase activity GO:0033673 112 63 1,000 2,827E-03 0,07891753 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 1,000 3,098E-03 0,0854708 ! negative regulation of transferase activity GO:0051348 117 66 1,000 3,098E-03 0,08448837 ! negative regulation of ligase activity GO:0051352 100 67 1,000 3,19E-03 0,08603224 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of caspase activity GO:0043281 104 68 1,000 3,285E-03 0,08757602 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 3,285E-03 0,08660295 ! regulation of endopeptidase activity GO:0052548 106 70 1,000 3,477E-03 0,09066296 ! regulation of actin cytoskeleton organization GO:0032956 120 72 1,000 3,674E-03 0,09476761 ! regulation of actin filament-based process GO:0032970 122 74 1,000 3,877E-03 0,09891482 ! regulation of Rho protein signal transduction GO:0035023 126 74 1,000 3,877E-03 0,09786254 ! regulation of peptidase activity GO:0052547 113 75 1,000 3,98E-03 0,09940897 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 3,98E-03 0,09837346 ! response to metal ion GO:0010038 114 76 1,000 4,084E-03 0,09991387 ! phosphoinositide-mediated signaling GO:0048015 122 76 1,000 4,084E-03 0,09889434 ! regulation of Ras GTPase activity GO:0032318 125 76 1,000 4,084E-03 0,09789541 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 4,19E-03 0,09942451 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 127 78 1,000 4,297E-03 0,10095309 ! response to unfolded protein GO:0006986 113 80 1,000 4,514E-03 0,10502813 ! response to inorganic substance GO:0010035 127 81 1,000 4,625E-03 0,10655972 ! positive regulation of protein modification process GO:0031401 126 83 1,000 4,85E-03 0,11067438 ! response to protein stimulus GO:0051789 127 85 1,000 5,081E-03 0,11482347 ! carbohydrate biosynthetic process GO:0016051 111 86 1,000 5,198E-03 0,11635899 ! regulation of GTPase activity GO:0043087 149 90 1,000 5,678E-03 0,12592271 ! cell cycle arrest GO:0007050 171 93 1,000 6,051E-03 0,1329544 ! regulation of cell adhesion GO:0030155 187 94 1,000 6,178E-03 0,13449522 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 6,27E-03 0,13526196 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 6,27E-03 0,13404338 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 6,27E-03 0,13284657 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,27E-03 0,13167093 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 6,27E-03 0,13051593 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,27E-03 0,129381 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 6,27E-03 0,12826565 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,27E-03 0,12716936 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 6,27E-03 0,12609166 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 6,27E-03 0,12503206 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 6,27E-03 0,12399013 ! response to oxygen radical GO:0000305 11 5 0,000 6,27E-03 0,12296542 ! negative regulation of bone resorption GO:0045779 11 5 0,000 6,27E-03 0,1219575 ! myoblast cell fate commitment GO:0048625 8 5 0,000 6,27E-03 0,12096598 ! nucleotide-sugar transport GO:0015780 8 5 0,000 6,27E-03 0,11999045 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 6,27E-03 0,11903052 ! regulation of interferon-beta production GO:0032648 5 5 0,000 6,27E-03 0,11808584 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 6,27E-03 0,11715603 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 6,27E-03 0,11624075 ! female meiosis GO:0007143 8 5 0,000 6,27E-03 0,11533965 ! nose development GO:0043584 10 5 0,000 6,27E-03 0,11445243 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 6,27E-03 0,11357874 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 6,27E-03 0,1127183 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,27E-03 0,11187079 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 6,27E-03 0,11103594 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 6,27E-03 0,11021345 ! cobalt ion transport GO:0006824 9 5 0,000 6,27E-03 0,10940306 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 6,27E-03 0,10860449 ! SMAD protein complex assembly GO:0007183 10 5 0,000 6,27E-03 0,1078175 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 6,27E-03 0,10704184 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 6,27E-03 0,10627725 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 6,27E-03 0,10552351 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 6,27E-03 0,10478039 ! adaptation of signaling pathway GO:0022401 9 5 0,000 6,27E-03 0,10404766 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 6,27E-03 0,10332511 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,27E-03 0,10261252 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 6,27E-03 0,1019097 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,27E-03 0,10121643 ! negative regulation of histone modification GO:0031057 7 5 0,000 6,27E-03 0,10053254 ! malate metabolic process GO:0006108 8 5 0,000 6,27E-03 0,09985782 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,27E-03 0,0991921 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 6,27E-03 0,0985352 ! clathrin coat assembly GO:0048268 11 5 0,000 6,27E-03 0,09788694 ! Notch receptor processing GO:0007220 8 5 0,000 6,27E-03 0,09724716 ! phototransduction, visible light GO:0007603 7 5 0,000 6,27E-03 0,09661569 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,27E-03 0,09599236 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 6,27E-03 0,09537702 ! mating behavior GO:0007617 6 5 0,000 6,27E-03 0,09476953 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 6,27E-03 0,09416972 ! copulation GO:0007620 8 5 0,000 6,27E-03 0,09357746 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,27E-03 0,0929926 ! embryonic hemopoiesis GO:0035162 13 5 0,000 6,27E-03 0,092415 ! regulation of potassium ion transport GO:0043266 9 5 0,000 6,27E-03 0,09184454 ! apoptotic cell clearance GO:0043277 14 5 0,000 6,27E-03 0,09128108 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 6,27E-03 0,09072448 ! lipoprotein particle clearance GO:0034381 9 5 0,000 6,27E-03 0,09017464 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 6,27E-03 0,08963142 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 6,27E-03 0,0890947 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 6,27E-03 0,08856438 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 6,27E-03 0,08804033 ! response to axon injury GO:0048678 8 5 0,000 6,27E-03 0,08752244 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,27E-03 0,08701062 ! response to protozoan GO:0001562 10 5 0,000 6,27E-03 0,08650474 ! negative regulation of heart contraction GO:0045822 12 5 0,000 6,27E-03 0,08600471 ! lymph vessel development GO:0001945 8 5 0,000 6,27E-03 0,08551043 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 6,27E-03 0,0850218 ! endochondral ossification GO:0001958 13 5 0,000 6,27E-03 0,08453872 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 6,27E-03 0,0840611 ! single strand break repair GO:0000012 5 5 0,000 6,27E-03 0,08358885 ! parathyroid gland development GO:0060017 8 5 0,000 6,27E-03 0,08312187 ! anagen GO:0042640 7 5 0,000 6,27E-03 0,08266009 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 6,27E-03 0,0822034 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 6,27E-03 0,08175173 ! skeletal myofibril assembly GO:0014866 8 5 0,000 6,27E-03 0,081305 ! smooth muscle tissue development GO:0048745 14 5 0,000 6,27E-03 0,08086313 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,27E-03 0,08042603 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 6,27E-03 0,07999363 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 6,27E-03 0,07956586 ! cardiac muscle fiber development GO:0048739 8 5 0,000 6,27E-03 0,07914264 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,27E-03 0,07872389 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 6 5 0,000 6,27E-03 0,07830956 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,27E-03 0,07789956 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 6,27E-03 0,07749383 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 6,27E-03 0,07709231 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,27E-03 0,07669493 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 6,27E-03 0,07630162 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 6,27E-03 0,07591232 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 6,27E-03 0,07552698 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 6,27E-03 0,07514553 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 6,27E-03 0,07476792 ! tyrosine catabolic process GO:0006572 7 5 0,000 6,27E-03 0,07439408 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 6,27E-03 0,07402396 ! proline biosynthetic process GO:0006561 6 5 0,000 6,27E-03 0,0736575 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,27E-03 0,07329466 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,27E-03 0,07293537 ! polyol catabolic process GO:0046174 7 5 0,000 6,27E-03 0,07257959 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 6,27E-03 0,07222726 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,27E-03 0,07187834 ! sister chromatid cohesion GO:0007062 10 5 0,000 6,27E-03 0,07153277 ! response to ATP GO:0033198 6 5 0,000 6,27E-03 0,0711905 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 6,27E-03 0,0708515 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 6,27E-03 0,07051571 ! neutrophil activation GO:0042119 6 5 0,000 6,27E-03 0,07018309 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 6,27E-03 0,06985359 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 6,27E-03 0,06952718 ! response to food GO:0032094 5 5 0,000 6,27E-03 0,06920379 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 6,27E-03 0,06888341 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 6,27E-03 0,06856597 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 6,27E-03 0,06825145 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,27E-03 0,0679398 ! paraxial mesoderm development GO:0048339 9 5 0,000 6,27E-03 0,06763098 ! forebrain neuron development GO:0021884 7 5 0,000 6,27E-03 0,06732496 ! melanosome organization GO:0032438 7 5 0,000 6,27E-03 0,06702169 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 6,27E-03 0,06672115 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 6,27E-03 0,06642328 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 6,27E-03 0,06612807 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 6,27E-03 0,06583547 ! mesodermal cell fate determination GO:0007500 7 5 0,000 6,27E-03 0,06554544 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,27E-03 0,06525796 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 6,27E-03 0,06497299 ! nucleoside salvage GO:0043174 7 5 0,000 6,27E-03 0,0646905 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 6,27E-03 0,06441046 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 6,27E-03 0,06413283 ! negative regulation of platelet activation GO:0010544 8 5 0,000 6,27E-03 0,06385758 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 6,27E-03 0,06358468 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,27E-03 0,06331411 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 6,27E-03 0,06304583 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 6,27E-03 0,06277981 ! early endosome to late endosome transport GO:0045022 11 5 0,000 6,27E-03 0,06251603 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 6,27E-03 0,06225446 ! depyrimidination GO:0045008 8 5 0,000 6,27E-03 0,06199506 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,27E-03 0,06173782 ! 5S class rRNA transcription GO:0042791 8 5 0,000 6,27E-03 0,06148271 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 6,27E-03 0,06122969 ! neuronal ion channel clustering GO:0045161 8 5 0,000 6,27E-03 0,06097875 ! sodium ion homeostasis GO:0055078 6 5 0,000 6,27E-03 0,06072986 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 6,27E-03 0,06048299 ! monocyte differentiation GO:0030224 7 5 0,000 6,27E-03 0,06023812 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 6,27E-03 0,05999522 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 6,27E-03 0,05975428 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 6,27E-03 0,05951526 ! response to UV-C GO:0010225 7 5 0,000 6,27E-03 0,05927815 ! protein targeting to vacuole GO:0006623 6 5 0,000 6,27E-03 0,05904292 ! activated T cell proliferation GO:0050798 7 5 0,000 6,27E-03 0,05880955 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 6,27E-03 0,05857801 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 6,27E-03 0,0583483 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 6,27E-03 0,05812037 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 6,27E-03 0,05789422 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 6,27E-03 0,05766983 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,27E-03 0,05744716 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 6,27E-03 0,05722621 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 6,27E-03 0,05700696 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 6,27E-03 0,05678937 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 6,27E-03 0,05657344 ! response to cadmium ion GO:0046686 8 5 0,000 6,27E-03 0,05635915 ! melanosome transport GO:0032402 8 5 0,000 6,27E-03 0,05614647 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,27E-03 0,0559354 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 6,27E-03 0,0557259 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 6,27E-03 0,05551797 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 6,27E-03 0,05531158 ! positive T cell selection GO:0043368 10 5 0,000 6,27E-03 0,05510672 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 6,27E-03 0,05490338 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 6,27E-03 0,05470153 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 6,27E-03 0,05450116 ! ribosomal subunit assembly GO:0042257 5 5 0,000 6,27E-03 0,05430225 ! base conversion or substitution editing GO:0016553 6 5 0,000 6,27E-03 0,05410478 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 6,27E-03 0,05390875 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 6,27E-03 0,05371414 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 6,27E-03 0,05352092 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 6,27E-03 0,05332909 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 6,27E-03 0,05313863 ! histone demethylation GO:0016577 10 5 0,000 6,27E-03 0,05294952 ! mitotic recombination GO:0006312 10 5 0,000 6,27E-03 0,05276176 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 6,27E-03 0,05257532 ! regulation of sterol transport GO:0032371 7 5 0,000 6,27E-03 0,0523902 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 6,27E-03 0,05220637 ! sympathetic nervous system development GO:0048485 13 5 0,000 6,27E-03 0,05202383 ! enteric nervous system development GO:0048484 9 5 0,000 6,27E-03 0,05184256 ! oxygen homeostasis GO:0032364 8 5 0,000 6,27E-03 0,05166255 ! establishment of planar polarity GO:0001736 7 5 0,000 6,27E-03 0,05148379 ! lymphocyte costimulation GO:0031294 12 5 0,000 6,27E-03 0,05130626 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 6,27E-03 0,05112995 ! transcription termination GO:0006353 8 5 0,000 6,27E-03 0,05095485 ! plasminogen activation GO:0031639 5 5 0,000 6,27E-03 0,05078094 ! B cell homeostasis GO:0001782 12 5 0,000 6,27E-03 0,05060822 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,27E-03 0,05043666 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 6,27E-03 0,05026627 ! regulation of hair follicle development GO:0051797 9 5 0,000 6,27E-03 0,05009702 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 6,27E-03 0,04992891 ! apical protein localization GO:0045176 8 5 0,000 6,27E-03 0,04976192 ! definitive hemopoiesis GO:0060216 5 5 0,000 6,27E-03 0,04959605 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 6,27E-03 0,04943128 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 6,27E-03 0,0492676 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 6,27E-03 0,049105 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 6,27E-03 0,04894347 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 6,27E-03 0,048783 ! regulation of centrosome duplication GO:0010824 6 5 0,000 6,27E-03 0,04862358 ! disaccharide metabolic process GO:0005984 9 5 0,000 6,27E-03 0,0484652 ! galactolipid metabolic process GO:0019374 8 5 0,000 6,27E-03 0,04830784 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 6,27E-03 0,04815151 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 6,27E-03 0,04799618 ! determination of adult lifespan GO:0008340 8 5 0,000 6,27E-03 0,04784185 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 6,27E-03 0,04768851 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 6,27E-03 0,04753615 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 6,27E-03 0,04738476 ! T cell activation during immune response GO:0002286 9 5 0,000 6,27E-03 0,04723433 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 6,27E-03 0,04708486 ! negative regulation of lipase activity GO:0060192 7 5 0,000 6,27E-03 0,04693633 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 6,27E-03 0,04678873 ! neural plate development GO:0001840 7 5 0,000 6,27E-03 0,04664205 ! regulation of sensory perception GO:0051931 6 5 0,000 6,27E-03 0,0464963 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 6,27E-03 0,04635145 ! regulation of histone acetylation GO:0035065 7 5 0,000 6,27E-03 0,0462075 ! sensory cilium assembly GO:0035058 6 5 0,000 6,27E-03 0,04606444 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 6,27E-03 0,04592227 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 6,27E-03 0,04578097 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,27E-03 0,04564054 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 6,27E-03 0,04550096 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 6,27E-03 0,04536224 ! receptor biosynthetic process GO:0032800 6 5 0,000 6,27E-03 0,04522436 ! penetration of zona pellucida GO:0007341 9 5 0,000 6,27E-03 0,04508732 ! drug metabolic process GO:0017144 5 5 0,000 6,27E-03 0,0449511 ! protein amino acid prenylation GO:0018346 9 5 0,000 6,27E-03 0,04481571 ! organ regeneration GO:0031100 7 5 0,000 6,27E-03 0,04468113 ! carnitine metabolic process GO:0009437 5 5 0,000 6,27E-03 0,04454735 GO:0006577|betaine metabolic process, ! polysaccharide metabolic process GO:0005976 141 98 1,000 6,697E-03 0,04743983 ! sulfur metabolic process GO:0006790 136 99 1,000 6,83E-03 0,04823686 ! tRNA transcription GO:0009304 11 6 0,000 7,52E-03 0,052949 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 7,52E-03 0,05279234 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,52E-03 0,05263661 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 7,52E-03 0,0524818 ! regulation of helicase activity GO:0051095 11 6 0,000 7,52E-03 0,0523279 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 7,52E-03 0,05217489 ! sleep GO:0030431 13 6 0,000 7,52E-03 0,05202278 ! positive regulation of axon extension GO:0045773 10 6 0,000 7,52E-03 0,05187155 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 7,52E-03 0,05172119 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 7,52E-03 0,05157171 ! forebrain regionalization GO:0021871 7 6 0,000 7,52E-03 0,05142309 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 7,52E-03 0,05127532 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 7,52E-03 0,0511284 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 7,52E-03 0,05098232 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 7,52E-03 0,05083707 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 7,52E-03 0,05069265 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 7,52E-03 0,05054904 ! neuron adhesion GO:0007158 9 6 0,000 7,52E-03 0,05040625 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 7,52E-03 0,05026426 ! signal peptide processing GO:0006465 8 6 0,000 7,52E-03 0,05012307 ! embryonic camera-type eye development GO:0031076 11 6 0,000 7,52E-03 0,04998267 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 7,52E-03 0,04984305 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 7,52E-03 0,04970421 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 7,52E-03 0,04956615 ! fibril organization GO:0043206 13 6 0,000 7,52E-03 0,04942884 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 7,52E-03 0,0492923 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 7,52E-03 0,04915651 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 7,52E-03 0,04902146 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 7,52E-03 0,04888716 ! protein refolding GO:0042026 13 6 0,000 7,52E-03 0,04875359 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 7,52E-03 0,04862074 ! rhythmic behavior GO:0007622 14 6 0,000 7,52E-03 0,04848862 ! glial cell fate commitment GO:0021781 17 6 0,000 7,52E-03 0,04835721 ! erythrocyte maturation GO:0043249 7 6 0,000 7,52E-03 0,04822652 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 7,52E-03 0,04809653 ! protein amino acid dealkylation GO:0008214 12 6 0,000 7,52E-03 0,04796724 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 7,52E-03 0,04783864 ! regulation of odontogenesis GO:0042481 8 6 0,000 7,52E-03 0,04771073 ! mechanosensory behavior GO:0007638 8 6 0,000 7,52E-03 0,0475835 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 7,52E-03 0,04745695 ! negative regulation of endocytosis GO:0045806 8 6 0,000 7,52E-03 0,04733107 ! response to interferon-gamma GO:0034341 12 6 0,000 7,52E-03 0,04720585 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 7,52E-03 0,0470813 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 7,52E-03 0,0469574 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 7,52E-03 0,04683415 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 7,52E-03 0,04671155 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 7,52E-03 0,04658959 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 7,52E-03 0,04646826 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 7,52E-03 0,04634756 ! cGMP-mediated signaling GO:0019934 11 6 0,000 7,52E-03 0,04622749 ! activation of MAPKKK activity GO:0000185 11 6 0,000 7,52E-03 0,04610804 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 7,52E-03 0,04598921 ! protein lipoylation GO:0009249 10 6 0,000 7,52E-03 0,04587098 ! pigment granule organization GO:0048753 11 6 0,000 7,52E-03 0,04575336 ! drug transport GO:0015893 6 6 0,000 7,52E-03 0,04563635 ! transepithelial chloride transport GO:0030321 10 6 0,000 7,52E-03 0,04551993 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 7,52E-03 0,0454041 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 7,52E-03 0,04528886 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 7,52E-03 0,04517421 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 7,52E-03 0,04506013 ! glutamate catabolic process GO:0006538 11 6 0,000 7,52E-03 0,04494663 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 7,52E-03 0,0448337 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 7,52E-03 0,04472133 ! adenohypophysis development GO:0021984 10 6 0,000 7,52E-03 0,04460953 ! response to pH GO:0009268 10 6 0,000 7,52E-03 0,04449828 ! hyperosmotic response GO:0006972 9 6 0,000 7,52E-03 0,04438759 ! microtubule nucleation GO:0007020 10 6 0,000 7,52E-03 0,04427745 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 7,52E-03 0,04416785 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 7,52E-03 0,0440588 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 7,52E-03 0,04395028 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 7,52E-03 0,04384229 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 7,52E-03 0,04373483 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 7,52E-03 0,0436279 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 7,52E-03 0,04352149 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 7,52E-03 0,0434156 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 7,52E-03 0,04331022 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 7,52E-03 0,04320536 ! purine salvage GO:0043101 9 6 0,000 7,52E-03 0,043101 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,52E-03 0,04299714 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 7,52E-03 0,04289378 ! nucleoside transport GO:0015858 7 6 0,000 7,52E-03 0,04279092 ! organic alcohol transport GO:0015850 9 6 0,000 7,52E-03 0,04268855 ! T cell mediated immunity GO:0002456 12 6 0,000 7,52E-03 0,04258666 ! folic acid transport GO:0015884 11 6 0,000 7,52E-03 0,04248527 ! male sex determination GO:0030238 11 6 0,000 7,52E-03 0,04238435 ! carnitine transport GO:0015879 8 6 0,000 7,52E-03 0,04228392 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 7,52E-03 0,04218395 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,52E-03 0,04208446 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 7,52E-03 0,04198544 ! positive regulation of exocytosis GO:0045921 9 6 0,000 7,52E-03 0,04188688 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 7,52E-03 0,04178879 ! parturition GO:0007567 13 6 0,000 7,52E-03 0,04169115 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 7,52E-03 0,04159397 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 7,52E-03 0,04149724 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 7,52E-03 0,04140096 ! regulation of centrosome cycle GO:0046605 8 6 0,000 7,52E-03 0,04130512 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 7,52E-03 0,04120973 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 7,52E-03 0,04111477 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 7,52E-03 0,04102026 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 7,52E-03 0,04092617 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 7,52E-03 0,04083252 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 7,52E-03 0,0407393 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 7,52E-03 0,0406465 ! neural nucleus development GO:0048857 12 6 0,000 7,52E-03 0,04055412 ! forebrain morphogenesis GO:0048853 14 6 0,000 7,52E-03 0,04046216 ! hyaluronan metabolic process GO:0030212 7 6 0,000 7,52E-03 0,04037062 ! purine base biosynthetic process GO:0009113 14 6 0,000 7,52E-03 0,04027949 ! interaction with symbiont GO:0051702 9 6 0,000 7,52E-03 0,04018877 ! regulation of dendrite development GO:0050773 13 6 0,000 7,52E-03 0,04009845 ! anterograde axon cargo transport GO:0008089 9 6 0,000 7,52E-03 0,04000855 ! positive regulation of organ growth GO:0046622 7 6 0,000 7,52E-03 0,03991904 ! eating behavior GO:0042755 6 6 0,000 7,52E-03 0,03982994 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 7,52E-03 0,03974123 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 7,52E-03 0,03965292 ! response to copper ion GO:0046688 9 6 0,000 7,52E-03 0,03956499 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 7,52E-03 0,03947746 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 7,52E-03 0,03939031 ! establishment of melanosome localization GO:0032401 9 6 0,000 7,52E-03 0,03930355 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,52E-03 0,03921717 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 7,52E-03 0,03913117 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 7,52E-03 0,03904554 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,52E-03 0,03896029 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,52E-03 0,03887541 ! hair follicle maturation GO:0048820 8 6 0,000 7,52E-03 0,0387909 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 7,52E-03 0,03870675 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 7,52E-03 0,03862297 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 7,52E-03 0,03853955 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 7,52E-03 0,03845649 ! rhombomere development GO:0021546 6 6 0,000 7,52E-03 0,03837379 ! G2 phase GO:0051319 15 6 0,000 7,52E-03 0,03829144 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 7,52E-03 0,03820945 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 7,52E-03 0,0381278 ! muscle cell proliferation GO:0033002 9 6 0,000 7,52E-03 0,03804651 ! membrane to membrane docking GO:0022614 12 6 0,000 7,52E-03 0,03796556 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 7,52E-03 0,03788495 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 7,52E-03 0,03780469 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 7,52E-03 0,03772476 ! receptor internalization GO:0031623 9 6 0,000 7,52E-03 0,03764517 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 7,52E-03 0,03756592 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 7,52E-03 0,037487 ! coenzyme A metabolic process GO:0015936 9 6 0,000 7,52E-03 0,03740841 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 7,52E-03 0,03733015 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 7,52E-03 0,03725222 ! peptidyl-histidine modification GO:0018202 10 6 0,000 7,52E-03 0,03717461 ! axonal fasciculation GO:0007413 10 6 0,000 7,52E-03 0,03709732 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 7,52E-03 0,03702036 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 7,52E-03 0,03694371 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 7,52E-03 0,03686738 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 7,52E-03 0,03679137 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,52E-03 0,03671566 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 7,52E-03 0,03664027 ! progesterone metabolic process GO:0042448 8 6 0,000 7,52E-03 0,03656519 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,52E-03 0,03649041 ! glycolipid catabolic process GO:0019377 14 6 0,000 7,52E-03 0,03641594 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 7,52E-03 0,03634178 ! negative regulation of axon extension GO:0030517 13 6 0,000 7,52E-03 0,03626791 ! removal of superoxide radicals GO:0019430 10 6 0,000 7,52E-03 0,03619435 ! triglyceride catabolic process GO:0019433 8 6 0,000 7,52E-03 0,03612108 ! protein modification by small protein removal GO:0070646 10 6 0,000 7,52E-03 0,03604811 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 7,52E-03 0,03597543 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 7,52E-03 0,03590304 ! glial cell migration GO:0008347 11 6 0,000 7,52E-03 0,03583095 ! blastocyst growth GO:0001832 17 6 0,000 7,52E-03 0,03575914 ! pigment granule transport GO:0051904 12 6 0,000 7,52E-03 0,03568762 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 7,52E-03 0,03561639 ! cerebellar cortex formation GO:0021697 9 6 0,000 7,52E-03 0,03554544 ! catecholamine transport GO:0051937 7 6 0,000 7,52E-03 0,03547478 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 7,52E-03 0,03540439 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 7,52E-03 0,03533428 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,52E-03 0,03526445 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 7,52E-03 0,0351949 ! spindle assembly GO:0051225 6 6 0,000 7,52E-03 0,03512561 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 7,52E-03 0,03505661 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 7,52E-03 0,03498787 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 7,52E-03 0,0349194 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 7,52E-03 0,0348512 ! NAD biosynthetic process GO:0009435 9 6 0,000 7,52E-03 0,03478326 ! positive regulation of coagulation GO:0050820 11 6 0,000 7,52E-03 0,03471559 ! cellular anion homeostasis GO:0030002 9 6 0,000 7,52E-03 0,03464818 GO:0055081|anion homeostasis, ! behavioral response to cocaine GO:0048148 13 7 0,000 8,767E-03 0,04032021 ! autophagic vacuole formation GO:0000045 12 7 0,000 8,767E-03 0,04024222 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 8,767E-03 0,04016454 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 8,767E-03 0,04008715 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 8,767E-03 0,04001006 ! prostate gland development GO:0030850 11 7 0,000 8,767E-03 0,03993326 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 8,767E-03 0,03985676 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 8,767E-03 0,03978055 ! synaptonemal complex assembly GO:0007130 11 7 0,000 8,767E-03 0,03970464 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 8,767E-03 0,03962901 ! male meiosis GO:0007140 10 7 0,000 8,767E-03 0,03955367 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,767E-03 0,03947861 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 8,767E-03 0,03940384 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 8,767E-03 0,03932936 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 8,767E-03 0,03925515 ! oligopeptide transport GO:0006857 11 7 0,000 8,767E-03 0,03918122 ! protein amino acid sulfation GO:0006477 9 7 0,000 8,767E-03 0,03910757 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 8,767E-03 0,0390342 ! establishment of tissue polarity GO:0007164 10 7 0,000 8,767E-03 0,0389611 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 8,767E-03 0,03888828 ! RNA methylation GO:0001510 11 7 0,000 8,767E-03 0,03881573 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 8,767E-03 0,03874344 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 8,767E-03 0,03867143 ! pericardium development GO:0060039 9 7 0,000 8,767E-03 0,03859968 ! macrophage chemotaxis GO:0048246 10 7 0,000 8,767E-03 0,0385282 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 8,767E-03 0,03845699 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 8,767E-03 0,03838603 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 8,767E-03 0,03831534 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 8,767E-03 0,03824491 ! cerebral cortex cell migration GO:0021795 11 7 0,000 8,767E-03 0,03817473 ! opsonization GO:0008228 9 7 0,000 8,767E-03 0,03810482 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 8,767E-03 0,03803516 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 8,767E-03 0,03796575 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 8,767E-03 0,03789659 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 8,767E-03 0,03782769 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 8,767E-03 0,03775904 ! chemosensory behavior GO:0007635 9 7 0,000 8,767E-03 0,03769063 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 8,767E-03 0,03762248 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 8,767E-03 0,03755457 ! leukocyte degranulation GO:0043299 11 7 0,000 8,767E-03 0,0374869 ! positive regulation of glycolysis GO:0045821 13 7 0,000 8,767E-03 0,03741948 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 8,767E-03 0,0373523 ! positive regulation of heart rate GO:0010460 11 7 0,000 8,767E-03 0,03728536 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,767E-03 0,03721866 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 8,767E-03 0,0371522 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 8,767E-03 0,03708597 ! spinal cord patterning GO:0021511 9 7 0,000 8,767E-03 0,03701998 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 8,767E-03 0,03695423 ! thymic T cell selection GO:0045061 15 7 0,000 8,767E-03 0,03688871 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 8,767E-03 0,03682342 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 8,767E-03 0,03675836 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 8,767E-03 0,03669353 ! ovulation GO:0030728 8 7 0,000 8,767E-03 0,03662893 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 8,767E-03 0,03656455 ! histidine metabolic process GO:0006547 7 7 0,000 8,767E-03 0,0365004 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 8,767E-03 0,03643648 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 8,767E-03 0,03637278 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 8,767E-03 0,0363093 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 8,767E-03 0,03624604 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 8,767E-03 0,03618301 ! thyroid hormone generation GO:0006590 11 7 0,000 8,767E-03 0,03612019 ! endosome organization GO:0007032 10 7 0,000 8,767E-03 0,03605759 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 8,767E-03 0,03599521 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 8,767E-03 0,03593304 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 8,767E-03 0,03587109 ! urea metabolic process GO:0019627 9 7 0,000 8,767E-03 0,03580935 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 8,767E-03 0,03574782 ! vesicle fusion GO:0006906 15 7 0,000 8,767E-03 0,0356865 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 8,767E-03 0,03562539 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 8,767E-03 0,0355645 ! intracellular pH reduction GO:0051452 11 7 0,000 8,767E-03 0,03550381 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 8,767E-03 0,03544332 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 8,767E-03 0,03538304 ! organ growth GO:0035265 13 7 0,000 8,767E-03 0,03532297 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 8,767E-03 0,0352631 ! Rac protein signal transduction GO:0016601 7 7 0,000 8,767E-03 0,03520343 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 8,767E-03 0,03514397 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 8,767E-03 0,0350847 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 8,767E-03 0,03502564 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 8,767E-03 0,03496677 ! rRNA modification GO:0000154 12 7 0,000 8,767E-03 0,0349081 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 8,767E-03 0,03484963 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 8,767E-03 0,03479135 ! protein heterooligomerization GO:0051291 10 7 0,000 8,767E-03 0,03473327 ! response to UV-B GO:0010224 11 7 0,000 8,767E-03 0,03467538 ! astrocyte development GO:0014002 15 7 0,000 8,767E-03 0,03461769 ! intermediate filament organization GO:0045109 12 7 0,000 8,767E-03 0,03456018 ! cardiac muscle cell development GO:0055013 9 7 0,000 8,767E-03 0,03450287 ! fibrinolysis GO:0042730 9 7 0,000 8,767E-03 0,03444574 ! peptidyl-arginine modification GO:0018195 9 7 0,000 8,767E-03 0,03438881 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 8,767E-03 0,03433206 ! blastoderm segmentation GO:0007350 11 7 0,000 8,767E-03 0,0342755 ! skeletal muscle contraction GO:0003009 8 7 0,000 8,767E-03 0,03421913 ! B cell lineage commitment GO:0002326 17 7 0,000 8,767E-03 0,03416294 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 8,767E-03 0,03410693 ! melanosome localization GO:0032400 10 7 0,000 8,767E-03 0,03405111 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 8,767E-03 0,03399547 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 8,767E-03 0,03394002 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 8,767E-03 0,03388474 ! mast cell activation GO:0045576 10 7 0,000 8,767E-03 0,03382964 ! multicellular organismal aging GO:0010259 11 7 0,000 8,767E-03 0,03377472 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 8,767E-03 0,03371998 ! gas homeostasis GO:0033483 12 7 0,000 8,767E-03 0,03366542 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 8,767E-03 0,03361103 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 8,767E-03 0,03355682 ! Schwann cell development GO:0014044 16 7 0,000 8,767E-03 0,03350279 ! dendrite morphogenesis GO:0048813 12 7 0,000 8,767E-03 0,03344892 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 8,767E-03 0,03339523 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 8,767E-03 0,03334171 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 8,767E-03 0,03328837 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 8,767E-03 0,03323519 ! neural tube patterning GO:0021532 8 7 0,000 8,767E-03 0,03318218 ! histone ubiquitination GO:0016574 10 7 0,000 8,767E-03 0,03312935 ! regulation of meiosis GO:0040020 12 7 0,000 8,767E-03 0,03307668 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 8,767E-03 0,03302417 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 8,767E-03 0,03297184 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 8,767E-03 0,03291967 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 8,767E-03 0,03286766 ! regulation of lipid transport GO:0032368 13 7 0,000 8,767E-03 0,03281582 ! regulation of cell division GO:0051302 9 7 0,000 8,767E-03 0,03276414 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 8,767E-03 0,03271263 ! neutrophil homeostasis GO:0001780 8 7 0,000 8,767E-03 0,03266127 ! regulation of macrophage activation GO:0043030 12 7 0,000 8,767E-03 0,03261008 ! negative regulation of nuclear division GO:0051784 18 7 0,000 8,767E-03 0,03255905 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 8,767E-03 0,03250817 ! diuresis GO:0030146 11 7 0,000 8,767E-03 0,03245746 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 8,767E-03 0,0324069 ! positive regulation of epidermis development GO:0045684 11 7 0,000 8,767E-03 0,0323565 ! thiamin metabolic process GO:0006772 8 7 0,000 8,767E-03 0,03230626 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 8,767E-03 0,03225617 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 8,767E-03 0,03220624 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 8,767E-03 0,03215646 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 8,767E-03 0,03210684 ! dopamine biosynthetic process GO:0042416 15 7 0,000 8,767E-03 0,03205736 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 8,767E-03 0,03200805 ! lymph node development GO:0048535 9 7 0,000 8,767E-03 0,03195888 ! anterior/posterior axis specification GO:0009948 11 7 0,000 8,767E-03 0,03190986 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 8,767E-03 0,031861 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 8,767E-03 0,03181228 ! positive regulation of glucose import GO:0046326 7 7 0,000 8,767E-03 0,03176371 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 8,767E-03 0,03171529 ! ATP catabolic process GO:0006200 10 7 0,000 8,767E-03 0,03166702 ! establishment of pigment granule localization GO:0051905 13 7 0,000 8,767E-03 0,03161889 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 8,767E-03 0,03157091 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 8,767E-03 0,03152308 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 8,767E-03 0,03147539 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 8,767E-03 0,03142784 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 8,767E-03 0,03138044 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,767E-03 0,03133318 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 8,767E-03 0,03128606 ! muscle adaptation GO:0043500 12 7 0,000 8,767E-03 0,03123908 ! amino sugar catabolic process GO:0046348 9 7 0,000 8,767E-03 0,03119225 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 8,767E-03 0,03114555 ! retina homeostasis GO:0001895 9 7 0,000 8,767E-03 0,031099 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 8,767E-03 0,03105258 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 8,767E-03 0,0310063 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 8,767E-03 0,03096016 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 8,767E-03 0,03091416 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 8,767E-03 0,03086829 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 0,01001394 0,03520455 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 0,01001394 0,03515247 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01001394 0,03510055 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01001394 0,03504878 ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 0,01001394 0,03499716 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 0,01001394 0,03494569 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 0,01001394 0,03489438 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 0,01001394 0,03484321 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 0,01001394 0,0347922 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01001394 0,03474133 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01001394 0,03469062 ! neutral lipid catabolic process GO:0046461 11 8 0,000 0,01001394 0,03464005 ! N-glycan processing GO:0006491 12 8 0,000 0,01001394 0,03458963 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01001394 0,03453935 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 0,01001394 0,03448922 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 0,01001394 0,03443924 ! mRNA stabilization GO:0048255 16 8 0,000 0,01001394 0,0343894 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 0,01001394 0,0343397 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01001394 0,03429015 ! lipoprotein transport GO:0042953 14 8 0,000 0,01001394 0,03424074 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01001394 0,03419147 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01001394 0,03414235 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01001394 0,03409336 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01001394 0,03404452 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 0,01001394 0,03399581 ! bile acid and bile salt transport GO:0015721 12 8 0,000 0,01001394 0,03394725 ! ganglioside metabolic process GO:0001573 16 8 0,000 0,01001394 0,03389882 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 0,01001394 0,03385053 ! reflex GO:0060004 16 8 0,000 0,01001394 0,03380238 ! positive regulation of isotype switching GO:0045830 16 8 0,000 0,01001394 0,03375436 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01001394 0,03370649 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 0,01001394 0,03365874 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01001394 0,03361113 ! glycerolipid catabolic process GO:0046503 11 8 0,000 0,01001394 0,03356366 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 0,01001394 0,03351632 ! hemoglobin metabolic process GO:0020027 12 8 0,000 0,01001394 0,03346912 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01001394 0,03342204 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 0,01001394 0,0333751 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 0,01001394 0,03332829 ! adrenal gland development GO:0030325 18 8 0,000 0,01001394 0,03328161 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 0,01001394 0,03323507 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01001394 0,03318865 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01001394 0,03314236 ! proline metabolic process GO:0006560 9 8 0,000 0,01001394 0,0330962 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01001394 0,03305017 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 0,01001394 0,03300427 ! regulation of pigmentation during development GO:0048070 18 8 0,000 0,01001394 0,03295849 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 0,01001394 0,03291284 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 0,01001394 0,03286732 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01001394 0,03282192 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01001394 0,03277665 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 0,01001394 0,0327315 ! galactose metabolic process GO:0006012 14 8 0,000 0,01001394 0,03268648 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01001394 0,03264158 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01001394 0,03259681 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01001394 0,03255215 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 0,01001394 0,03250762 ! ruffle organization GO:0031529 12 8 0,000 0,01001394 0,03246321 ! osteoblast development GO:0002076 14 8 0,000 0,01001394 0,03241893 ! macroautophagy GO:0016236 14 8 0,000 0,01001394 0,03237476 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01001394 0,03233071 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01001394 0,03228678 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 0,01001394 0,03224297 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 0,01001394 0,03219929 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 0,01001394 0,03215571 ! protein retention in ER lumen GO:0006621 16 8 0,000 0,01001394 0,03211226 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 0,01001394 0,03206892 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 0,01001394 0,0320257 ! regulation of circadian rhythm GO:0042752 13 8 0,000 0,01001394 0,0319826 ! pigment granule localization GO:0051875 14 8 0,000 0,01001394 0,03193961 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 0,01001394 0,03189674 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 0,01001394 0,03185398 ! response to tropane GO:0014073 14 8 0,000 0,01001394 0,03181134 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 0,01001394 0,03176881 ! embryonic axis specification GO:0000578 12 8 0,000 0,01001394 0,0317264 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 0,01001394 0,0316841 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 0,01001394 0,03164191 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 0,01001394 0,03159983 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01001394 0,03155787 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01001394 0,03151601 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01001394 0,03147427 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 0,01001394 0,03143264 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 0,01001394 0,03139111 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 0,01001394 0,0313497 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 0,01001394 0,0313084 ! establishment of nucleus localization GO:0040023 14 8 0,000 0,01001394 0,0312672 ! icosanoid secretion GO:0032309 12 8 0,000 0,01001394 0,03122611 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 0,01001394 0,03118513 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 0,01001394 0,03114426 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 0,01001394 0,0311035 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 0,01001394 0,03106284 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 0,01001394 0,03102229 ! S phase GO:0051320 8 8 0,000 0,01001394 0,03098184 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 0,01001394 0,0309415 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 0,01001394 0,03090126 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 0,01001394 0,03086113 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01001394 0,03082111 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 0,01001394 0,03078118 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01001394 0,03074136 ! melanin biosynthetic process GO:0042438 11 8 0,000 0,01001394 0,03070164 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01001394 0,03066203 ! regulation of synaptogenesis GO:0051963 12 8 0,000 0,01001394 0,03062252 ! hormone catabolic process GO:0042447 13 8 0,000 0,01001394 0,0305831 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 0,01001394 0,03054379 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01001394 0,03050459 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 0,01001394 0,03046548 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 0,01001394 0,03042647 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01001394 0,03038756 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01001394 0,03034875 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01001394 0,03031004 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 0,01001394 0,03027143 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01001394 0,03023292 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01001394 0,0301945 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 0,01001394 0,03015618 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 0,01001394 0,03011796 ! negative regulation of B cell activation GO:0050869 17 8 0,000 0,01001394 0,03007984 ! behavioral response to nicotine GO:0035095 13 8 0,000 0,01001394 0,03004181 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01001394 0,03000388 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 0,01001394 0,02996604 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 0,01001394 0,0299283 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 0,01001394 0,02989066 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 0,01001394 0,02985311 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01125889 0,03352239 ! regulation of developmental growth GO:0048638 14 9 0,000 0,01125889 0,03348038 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 0,01125889 0,03343848 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01125889 0,03339668 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 0,01125889 0,03335499 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 0,01125889 0,0333134 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 0,01125889 0,03327191 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 0,01125889 0,03323053 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 0,01125889 0,03318925 ! cell volume homeostasis GO:0006884 14 9 0,000 0,01125889 0,03314807 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 0,01125889 0,03310699 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 0,01125889 0,03306602 ! UTP metabolic process GO:0046051 10 9 0,000 0,01125889 0,03302515 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 0,01125889 0,03298438 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 0,01125889 0,0329437 ! smoothened signaling pathway GO:0007224 10 9 0,000 0,01125889 0,03290313 ! protein complex disassembly GO:0043241 17 9 0,000 0,01125889 0,03286266 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01125889 0,03282229 ! estrogen metabolic process GO:0008210 16 9 0,000 0,01125889 0,03278202 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01125889 0,03274184 ! photoreceptor cell development GO:0042461 17 9 0,000 0,01125889 0,03270177 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 0,01125889 0,03266179 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 0,01125889 0,03262191 ! microtubule bundle formation GO:0001578 14 9 0,000 0,01125889 0,03258213 ! T-helper 1 type immune response GO:0042088 13 9 0,000 0,01125889 0,03254244 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 0,01125889 0,03250285 ! lung alveolus development GO:0048286 18 9 0,000 0,01125889 0,03246336 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01125889 0,03242396 ! pseudouridine synthesis GO:0001522 10 9 0,000 0,01125889 0,03238466 ! endothelial cell differentiation GO:0045446 17 9 0,000 0,01125889 0,03234545 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01125889 0,03230634 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01125889 0,03226732 ! endoderm development GO:0007492 12 9 0,000 0,01125889 0,0322284 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01125889 0,03218957 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01125889 0,03215084 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 0,01125889 0,03211219 ! astrocyte differentiation GO:0048708 17 9 0,000 0,01125889 0,03207364 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 0,01125889 0,03203518 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 0,01125889 0,03199682 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01125889 0,03195855 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 0,01125889 0,03192036 ! reverse cholesterol transport GO:0043691 17 9 0,000 0,01125889 0,03188227 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 0,01125889 0,03184427 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 0,01125889 0,03180636 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 0,01125889 0,03176854 ! macrophage activation GO:0042116 14 9 0,000 0,01125889 0,03173081 ! multicellular organism growth GO:0035264 16 9 0,000 0,01125889 0,03169317 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 0,01125889 0,03165562 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01125889 0,03161816 ! neuron apoptosis GO:0051402 12 9 0,000 0,01125889 0,03158079 ! lens development in camera-type eye GO:0002088 11 9 0,000 0,01125889 0,0315435 ! positive regulation of vasodilation GO:0045909 14 9 0,000 0,01125889 0,0315063 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01125889 0,03146919 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 0,01125889 0,03143217 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01125889 0,03139523 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 0,01125889 0,03135839 ! Schwann cell differentiation GO:0014037 20 9 0,000 0,01125889 0,03132162 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 0,01125889 0,03128495 ! regulation of gliogenesis GO:0014013 21 9 0,000 0,01125889 0,03124836 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 0,01125889 0,03121185 ! oligodendrocyte development GO:0014003 13 9 0,000 0,01125889 0,03117543 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 0,01125889 0,0311391 ! segment specification GO:0007379 11 9 0,000 0,01125889 0,03110285 ! cellular extravasation GO:0045123 12 9 0,000 0,01125889 0,03106668 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01125889 0,0310306 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 0,01125889 0,0309946 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01125889 0,03095868 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01125889 0,03092285 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 0,01125889 0,0308871 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 0,01125889 0,03085144 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 0,01125889 0,03081585 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 0,01125889 0,03078035 ! response to amine stimulus GO:0014075 13 9 0,000 0,01125889 0,03074493 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 0,01125889 0,03070959 ! erythrocyte development GO:0048821 13 9 0,000 0,01125889 0,03067433 ! renal water homeostasis GO:0003091 13 9 0,000 0,01125889 0,03063916 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 0,01125889 0,03060406 ! nucleosome disassembly GO:0006337 13 9 0,000 0,01125889 0,03056904 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 0,01125889 0,03053411 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 0,01125889 0,03049925 ! induction of an organ GO:0001759 13 9 0,000 0,01125889 0,03046447 ! leukocyte activation during immune response GO:0002366 15 9 0,000 0,01125889 0,03042978 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 0,01125889 0,03039516 ! cerebellum morphogenesis GO:0021587 13 9 0,000 0,01125889 0,03036062 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 0,01125889 0,03032616 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01125889 0,03029177 ! sterol catabolic process GO:0016127 11 9 0,000 0,01125889 0,03025747 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 0,01125889 0,03022324 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01125889 0,03018909 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 0,01125889 0,03015502 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 0,01125889 0,03012102 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 0,01125889 0,0300871 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 0,01125889 0,03005326 ! prophase GO:0051324 12 9 0,000 0,01125889 0,03001949 ! neuroblast proliferation GO:0007405 19 9 0,000 0,01125889 0,0299858 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 0,01125889 0,02995218 ! peptidyl-threonine modification GO:0018210 22 9 0,000 0,01125889 0,02991864 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 0,01125889 0,02988517 ! ubiquinone metabolic process GO:0006743 11 9 0,000 0,01125889 0,02985178 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 0,01125889 0,02981846 ! acid secretion GO:0046717 14 9 0,000 0,01125889 0,02978522 ! purine base metabolic process GO:0006144 18 9 0,000 0,01125889 0,02975205 ! detection of calcium ion GO:0005513 13 9 0,000 0,01125889 0,02971896 ! myeloid cell homeostasis GO:0002262 10 9 0,000 0,01125889 0,02968594 ! regulation of fibrinolysis GO:0051917 14 9 0,000 0,01125889 0,02965299 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01125889 0,02962012 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 0,01125889 0,02958731 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 0,01125889 0,02955458 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01125889 0,02952193 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01125889 0,02948934 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 0,01125889 0,02945683 ! prepulse inhibition GO:0060134 14 9 0,000 0,01125889 0,02942439 ! sequestering of metal ion GO:0051238 12 9 0,000 0,01125889 0,02939202 ! lamellipodium assembly GO:0030032 12 9 0,000 0,01125889 0,02935972 ! regulation of embryonic development GO:0045995 17 9 0,000 0,01125889 0,02932749 ! mitochondrion localization GO:0051646 15 9 0,000 0,01125889 0,02929533 ! localization within membrane GO:0051668 15 9 0,000 0,01125889 0,02926325 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01250234 0,03245957 ! axon extension GO:0048675 13 10 0,000 0,01250234 0,0324241 ! neuron fate specification GO:0048665 12 10 0,000 0,01250234 0,0323887 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,01250234 0,03235338 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,01250234 0,03231814 ! associative learning GO:0008306 19 10 0,000 0,01250234 0,03228297 ! positive regulation of B cell proliferation GO:0030890 14 10 0,000 0,01250234 0,03224788 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,01250234 0,03221287 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01250234 0,03217793 ! CTP metabolic process GO:0046036 11 10 0,000 0,01250234 0,03214307 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,01250234 0,03210828 ! GTP metabolic process GO:0046039 11 10 0,000 0,01250234 0,03207357 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01250234 0,03203893 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,01250234 0,03200437 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01250234 0,03196988 ! social behavior GO:0035176 15 10 0,000 0,01250234 0,03193547 ! sulfate transport GO:0008272 12 10 0,000 0,01250234 0,03190113 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,01250234 0,03186686 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,01250234 0,03183267 ! artery development GO:0060840 20 10 0,000 0,01250234 0,03179855 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,01250234 0,03176451 ! response to pain GO:0048265 20 10 0,000 0,01250234 0,03173053 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,01250234 0,03169663 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,01250234 0,03166281 ! phospholipid efflux GO:0033700 17 10 0,000 0,01250234 0,03162905 ! hippocampus development GO:0021766 19 10 0,000 0,01250234 0,03159537 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,01250234 0,03156175 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,01250234 0,03152821 ! blood vessel remodeling GO:0001974 23 10 0,000 0,01250234 0,03149474 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01250234 0,03146135 ! pathogenesis GO:0009405 13 10 0,000 0,01250234 0,03142802 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01250234 0,03139476 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,01250234 0,03136157 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,01250234 0,03132846 ! protein targeting to ER GO:0045047 21 10 0,000 0,01250234 0,03129541 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,01250234 0,03126243 ! arginine catabolic process GO:0006527 12 10 0,000 0,01250234 0,03122953 ! melanocyte differentiation GO:0030318 16 10 0,000 0,01250234 0,03119669 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,01250234 0,03116392 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01250234 0,03113122 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,01250234 0,03109858 ! B cell proliferation GO:0042100 16 10 0,000 0,01250234 0,03106602 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,01250234 0,03103352 ! mannose metabolic process GO:0006013 11 10 0,000 0,01250234 0,0310011 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01250234 0,03096874 ! forebrain cell migration GO:0021885 17 10 0,000 0,01250234 0,03093644 ! lipid digestion GO:0044241 15 10 0,000 0,01250234 0,03090422 ! substrate-bound cell migration GO:0006929 11 10 0,000 0,01250234 0,03087206 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01250234 0,03083997 ! receptor clustering GO:0043113 18 10 0,000 0,01250234 0,03080794 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01250234 0,03077598 ! UV protection GO:0009650 14 10 0,000 0,01250234 0,03074409 ! entry into host cell GO:0030260 21 10 0,000 0,01250234 0,03071227 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,01250234 0,03068051 ! behavioral fear response GO:0001662 19 10 0,000 0,01250234 0,03064881 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01250234 0,03061718 ! negative regulation of ossification GO:0030279 21 10 0,000 0,01250234 0,03058562 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,01250234 0,03055412 ! protein homotetramerization GO:0051289 20 10 0,000 0,01250234 0,03052268 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,01250234 0,03049131 ! response to dsRNA GO:0043331 19 10 0,000 0,01250234 0,03046001 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,01250234 0,03042877 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,01250234 0,03039759 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01250234 0,03036648 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01250234 0,03033543 ! postreplication repair GO:0006301 16 10 0,000 0,01250234 0,03030444 ! fucose catabolic process GO:0019317 17 10 0,000 0,01250234 0,03027352 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,01250234 0,03024266 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01250234 0,03021186 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,01250234 0,03018113 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,01250234 0,03015046 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,01250234 0,03011985 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01250234 0,0300893 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,01250234 0,03005881 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,01250234 0,03002839 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,01250234 0,02999803 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,01250234 0,02996773 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,01250234 0,02993749 ! oocyte differentiation GO:0009994 14 10 0,000 0,01250234 0,02990731 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,01250234 0,02987719 ! spleen development GO:0048536 17 10 0,000 0,01250234 0,02984713 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,01250234 0,02981713 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,01250234 0,0297872 ! blastocyst formation GO:0001825 14 10 0,000 0,01250234 0,02975732 ! embryonic gut development GO:0048566 13 10 0,000 0,01250234 0,0297275 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,01250234 0,02969775 ! cerebellar cortex development GO:0021695 14 10 0,000 0,01250234 0,02966805 ! activation of innate immune response GO:0002218 10 10 0,000 0,01250234 0,02963841 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01250234 0,02960883 ! insulin secretion GO:0030073 18 10 0,000 0,01250234 0,02957931 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 0,01250234 0,02954985 ! response to nicotine GO:0035094 18 10 0,000 0,01250234 0,02952045 ! establishment of cell polarity GO:0030010 12 10 0,000 0,01250234 0,0294911 ! nucleus localization GO:0051647 16 10 0,000 0,01250234 0,02946182 ! regulation of synapse organization GO:0050807 14 10 0,000 0,01250234 0,02943259 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,01374429 0,03232427 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,01374429 0,03229227 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,01374429 0,03226033 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,01374429 0,03222845 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,01374429 0,03219664 ! virus-host interaction GO:0019048 20 11 0,000 0,01374429 0,03216488 ! thyroid gland development GO:0030878 20 11 0,000 0,01374429 0,03213319 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,01374429 0,03210157 GO:0006740|NADPH regeneration, ! non-recombinational repair GO:0000726 19 11 0,000 0,01374429 0,03207 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,01374429 0,0320385 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,01374429 0,03200706 ! Golgi vesicle budding GO:0048194 18 11 0,000 0,01374429 0,03197568 ! elastic fiber assembly GO:0048251 17 11 0,000 0,01374429 0,03194436 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,01374429 0,0319131 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,01374429 0,03188191 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,01374429 0,03185077 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,01374429 0,0318197 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,01374429 0,03178869 ! bone resorption GO:0045453 16 11 0,000 0,01374429 0,03175773 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,01374429 0,03172684 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,01374429 0,03169601 ! ventral spinal cord development GO:0021517 15 11 0,000 0,01374429 0,03166523 ! regulated secretory pathway GO:0045055 15 11 0,000 0,01374429 0,03163452 ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,01374429 0,03160387 ! syncytium formation GO:0006949 15 11 0,000 0,01374429 0,03157327 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01374429 0,03154274 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,01374429 0,03151226 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,01374429 0,03148185 ! Golgi organization GO:0007030 19 11 0,000 0,01374429 0,03145149 ! response to X-ray GO:0010165 19 11 0,000 0,01374429 0,03142119 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,01374429 0,03139094 ! adult heart development GO:0007512 12 11 0,000 0,01374429 0,03136076 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01374429 0,03133064 ! epithelial cell development GO:0002064 16 11 0,000 0,01374429 0,03130057 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,01374429 0,03127056 ! temperature homeostasis GO:0001659 16 11 0,000 0,01374429 0,03124061 ! L-glutamate transport GO:0015813 15 11 0,000 0,01374429 0,03121071 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,01374429 0,03118087 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01374429 0,03115109 ! motor axon guidance GO:0008045 17 11 0,000 0,01374429 0,03112137 ! copper ion homeostasis GO:0055070 15 11 0,000 0,01374429 0,0310917 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,01374429 0,03106209 ! regulation of bone resorption GO:0045124 27 11 0,000 0,01374429 0,03103253 ! stem cell development GO:0048864 30 11 0,000 0,01374429 0,03100303 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,01374429 0,03097359 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,01374429 0,0309442 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,01374429 0,03091487 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,01374429 0,0308856 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01374429 0,03085638 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,01374429 0,03082721 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01374429 0,0307981 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,01374429 0,03076905 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,01374429 0,03074005 ! cranial nerve development GO:0021545 14 11 0,000 0,01374429 0,0307111 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01374429 0,03068221 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01374429 0,03065338 ! salivary gland development GO:0007431 24 11 0,000 0,01374429 0,03062459 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,01374429 0,03059586 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,01374429 0,03056719 ! musculoskeletal movement GO:0050881 16 11 0,000 0,01374429 0,03053857 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,01374429 0,03051 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01374429 0,03048149 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01374429 0,03045303 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 19 11 0,000 0,01374429 0,03042462 ! cholesterol efflux GO:0033344 20 11 0,000 0,01374429 0,03039626 ! digestive tract morphogenesis GO:0048546 16 11 0,000 0,01374429 0,03036796 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,01374429 0,03033971 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,01374429 0,03031152 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 0,01374429 0,03028337 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01374429 0,03025528 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,01374429 0,03022724 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01374429 0,03019925 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,01374429 0,03017132 ! defense response to fungus GO:0050832 13 11 0,000 0,01374429 0,03014343 ! lysogeny GO:0030069 20 11 0,000 0,01374429 0,0301156 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,01374429 0,03008782 ! acrosome reaction GO:0007340 14 11 0,000 0,01374429 0,03006008 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,01374429 0,0300324 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,01374429 0,03000478 ! rRNA transcription GO:0009303 19 12 0,000 0,01498473 0,0326827 ! reproductive cellular process GO:0048610 15 12 0,000 0,01498473 0,03265269 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01498473 0,03262273 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01498473 0,03259283 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01498473 0,03256298 ! phosphate transport GO:0006817 15 12 0,000 0,01498473 0,03253319 ! peroxisomal transport GO:0043574 22 12 0,000 0,01498473 0,03250345 ! mating GO:0007618 16 12 0,000 0,01498473 0,03247377 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01498473 0,03244414 ! heart looping GO:0001947 15 12 0,000 0,01498473 0,03241456 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01498473 0,03238504 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01498473 0,03235557 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01498473 0,03232616 ! T cell selection GO:0045058 25 12 0,000 0,01498473 0,0322968 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01498473 0,03226749 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,01498473 0,03223824 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01498473 0,03220904 ! plasma membrane organization GO:0007009 19 12 0,000 0,01498473 0,03217989 ! focal adhesion formation GO:0048041 28 12 0,000 0,01498473 0,03215079 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01498473 0,03212175 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01498473 0,03209276 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01498473 0,03206382 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01498473 0,03203493 ! monoamine transport GO:0015844 14 12 0,000 0,01498473 0,0320061 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01498473 0,03197732 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01498473 0,03194859 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01498473 0,03191991 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01498473 0,03189128 ! regulation of organ growth GO:0046620 14 12 0,000 0,01498473 0,0318627 ! vasoconstriction GO:0042310 18 12 0,000 0,01498473 0,03183418 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01498473 0,0318057 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01498473 0,03177728 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01498473 0,03174891 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01498473 0,03172059 ! histone deacetylation GO:0016575 14 12 0,000 0,01498473 0,03169231 ! histone acetylation GO:0016573 27 12 0,000 0,01498473 0,03166409 ! DNA methylation GO:0006306 19 12 0,000 0,01498473 0,03163592 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,01498473 0,0316078 ! protein sumoylation GO:0016925 14 12 0,000 0,01498473 0,03157973 ! chromatin silencing GO:0006342 23 12 0,000 0,01498473 0,03155171 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01498473 0,03152374 ! gland morphogenesis GO:0022612 24 12 0,000 0,01498473 0,03149582 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01498473 0,03146794 ! zymogen activation GO:0031638 16 12 0,000 0,01498473 0,03144012 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01498473 0,03141235 ! nucleosome positioning GO:0016584 13 12 0,000 0,01498473 0,03138462 ! T cell homeostasis GO:0043029 22 12 0,000 0,01498473 0,03135695 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01498473 0,03132932 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01498473 0,03130174 ! response to gamma radiation GO:0010332 21 12 0,000 0,01498473 0,03127421 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01498473 0,03124673 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01498473 0,03121929 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01498473 0,03119191 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01498473 0,03116457 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01498473 0,03113728 ! male genitalia development GO:0030539 15 12 0,000 0,01498473 0,03111004 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01498473 0,03108285 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01498473 0,0310557 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01498473 0,0310286 ! developmental induction GO:0031128 16 12 0,000 0,01498473 0,03100155 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,01498473 0,03097454 ! response to cold GO:0009409 15 12 0,000 0,01498473 0,03094759 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01498473 0,03092067 ! respiratory burst GO:0045730 22 13 0,000 0,01622369 0,03344814 ! lactation GO:0007595 22 13 0,000 0,01622369 0,0334191 ! tRNA modification GO:0006400 15 13 0,000 0,01622369 0,03339012 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,01622369 0,03336118 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,01622369 0,0333323 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01622369 0,03330347 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,01622369 0,03327468 ! water transport GO:0006833 21 13 0,000 0,01622369 0,03324595 GO:0042044|fluid transport, ! regulation of B cell proliferation GO:0030888 24 13 0,000 0,01622369 0,03321726 ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,01622369 0,03318863 ! copper ion transport GO:0006825 15 13 0,000 0,01622369 0,03316004 ! filopodium assembly GO:0046847 21 13 0,000 0,01622369 0,0331315 ! lipid localization GO:0010876 25 13 0,000 0,01622369 0,03310301 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,01622369 0,03307458 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,01622369 0,03304619 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,01622369 0,03301784 ! T cell proliferation GO:0042098 24 13 0,000 0,01622369 0,03298955 ! organelle fusion GO:0048284 29 13 0,000 0,01622369 0,03296131 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01622369 0,03293311 ! endocrine pancreas development GO:0031018 19 13 0,000 0,01622369 0,03290496 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,01622369 0,03287686 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,01622369 0,03284881 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,01622369 0,03282081 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,01622369 0,03279285 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,01622369 0,03276494 ! methionine metabolic process GO:0006555 16 13 0,000 0,01622369 0,03273708 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,01622369 0,03270927 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01622369 0,0326815 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,01622369 0,03265378 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,01622369 0,03262611 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,01622369 0,03259848 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,01622369 0,0325709 ! neutral amino acid transport GO:0015804 20 13 0,000 0,01622369 0,03254337 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,01622369 0,03251588 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,01622369 0,03248844 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,01622369 0,03246105 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,01622369 0,0324337 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01622369 0,0324064 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01622369 0,03237915 ! cellular pigmentation GO:0033059 24 13 0,000 0,01622369 0,03235194 ! histone methylation GO:0016571 16 13 0,000 0,01622369 0,03232477 ! regulation of epidermis development GO:0045682 21 13 0,000 0,01622369 0,03229766 ! oxygen transport GO:0015671 20 13 0,000 0,01622369 0,03227058 ! regulation of axon extension GO:0030516 26 13 0,000 0,01622369 0,03224356 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,01622369 0,03221657 ! detection of bacterium GO:0016045 13 13 0,000 0,01622369 0,03218964 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,01622369 0,03216274 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,01622369 0,0321359 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,01622369 0,0321091 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,01622369 0,03208234 ! actin filament polymerization GO:0030041 18 13 0,000 0,01622369 0,03205562 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,01746114 0,03447195 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,01746114 0,0344433 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,01746114 0,03441469 ! neuron maturation GO:0042551 24 14 0,000 0,01746114 0,03438613 ! regulation of S phase GO:0033261 25 14 0,000 0,01746114 0,03435762 ! regulation of chemokine production GO:0032642 18 14 0,000 0,01746114 0,03432915 ! myotube differentiation GO:0014902 21 14 0,000 0,01746114 0,03430073 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,01746114 0,03427236 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,01746114 0,03424404 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,01746114 0,03421576 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,01746114 0,03418753 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,01746114 0,03415934 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,01746114 0,03413121 ! RNA polyadenylation GO:0043631 21 14 0,000 0,01746114 0,03410312 ! cartilage condensation GO:0001502 22 14 0,000 0,01746114 0,03407507 ! response to cAMP GO:0051591 20 14 0,000 0,01746114 0,03404707 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,01746114 0,03401912 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,01746114 0,03399121 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,01746114 0,03396335 ! limbic system development GO:0021761 25 14 0,000 0,01746114 0,03393553 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,01746114 0,03390776 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,01746114 0,03388004 ! palate development GO:0060021 19 14 0,000 0,01746114 0,03385236 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,01746114 0,03382472 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,01746114 0,03379713 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,01746114 0,03376959 ! response to hexose stimulus GO:0009746 22 14 0,000 0,01746114 0,03374209 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,01746114 0,03371463 ! arginine metabolic process GO:0006525 17 14 0,000 0,01746114 0,03368722 ! glutamate metabolic process GO:0006536 21 14 0,000 0,01746114 0,03365986 ! glycine metabolic process GO:0006544 22 14 0,000 0,01746114 0,03363254 ! pituitary gland development GO:0021983 24 14 0,000 0,01746114 0,03360526 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,01746114 0,03357803 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,01746114 0,03355084 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,01746114 0,03352369 ! cytokine metabolic process GO:0042107 18 14 0,000 0,01746114 0,03349659 ! NAD metabolic process GO:0019674 25 14 0,000 0,01746114 0,03346954 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,01746114 0,03344252 ! regulation of heart rate GO:0002027 26 14 0,000 0,01746114 0,03341555 ! exocrine system development GO:0035272 29 14 0,000 0,01746114 0,03338863 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,01746114 0,03336174 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,01746114 0,0333349 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,01746114 0,03330811 ! axon cargo transport GO:0008088 29 14 0,000 0,01746114 0,03328135 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,01746114 0,03325464 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,01746114 0,03322798 ! genitalia development GO:0048806 18 14 0,000 0,01746114 0,03320135 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,01746114 0,03317477 ! autonomic nervous system development GO:0048483 26 14 0,000 0,01746114 0,03314823 ! tissue regeneration GO:0042246 24 14 0,000 0,01746114 0,03312173 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,01746114 0,03309528 ! water homeostasis GO:0030104 23 14 0,000 0,01746114 0,03306886 ! cofactor transport GO:0051181 22 14 0,000 0,01746114 0,03304249 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,01746114 0,03301616 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,01746114 0,03298988 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01746114 0,03296363 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01746114 0,03293743 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,01746114 0,03291127 ! cell killing GO:0001906 22 14 0,000 0,01746114 0,03288515 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,01746114 0,03285907 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,01746114 0,03283303 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,01746114 0,03280703 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,01746114 0,03278108 ! microspike assembly GO:0030035 25 14 0,000 0,01746114 0,03275517 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,01746114 0,03272929 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,0186971 0,03501833 ! superoxide anion generation GO:0042554 19 15 0,000 0,0186971 0,03499071 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,0186971 0,03496314 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,0186971 0,03493561 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,0186971 0,03490812 ! inositol metabolic process GO:0006020 21 15 0,000 0,0186971 0,03488067 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,0186971 0,03485327 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,0186971 0,03482592 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,0186971 0,0347986 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,0186971 0,03477133 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,0186971 0,0347441 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,0186971 0,03471692 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,0186971 0,03468977 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,0186971 0,03466267 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0186971 0,03463561 ! response to osmotic stress GO:0006970 23 15 0,000 0,0186971 0,03460859 ! vesicle coating GO:0006901 26 15 0,000 0,0186971 0,03458162 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,0186971 0,03455469 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,0186971 0,0345278 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,0186971 0,03450095 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,0186971 0,03447414 ! bone mineralization GO:0030282 17 15 0,000 0,0186971 0,03444737 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,0186971 0,03442065 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,0186971 0,03439397 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,0186971 0,03436733 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,0186971 0,03434073 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,0186971 0,03431417 ! regulation of cellular pH GO:0030641 23 15 0,000 0,0186971 0,03428765 ! ribosome assembly GO:0042255 17 15 0,000 0,0186971 0,03426117 ! cerebellum development GO:0021549 19 15 0,000 0,0186971 0,03423474 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,0186971 0,03420834 ! mRNA splice site selection GO:0006376 33 15 0,000 0,0186971 0,03418199 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,0186971 0,03415567 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,0186971 0,0341294 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,0186971 0,03410317 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,0186971 0,03407697 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,0186971 0,03405082 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,0186971 0,03402471 ! muscle maintenance GO:0046716 21 15 0,000 0,0186971 0,03399863 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,0186971 0,0339726 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,0186971 0,03394661 ! intestinal absorption GO:0050892 22 15 0,000 0,0186971 0,03392066 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,0186971 0,03389474 ! dopamine metabolic process GO:0042417 32 15 0,000 0,0186971 0,03386887 ! gas transport GO:0015669 23 15 0,000 0,0186971 0,03384303 ! regulation of RNA stability GO:0043487 31 15 0,000 0,0186971 0,03381724 ! organic cation transport GO:0015695 19 15 0,000 0,0186971 0,03379148 ! heme biosynthetic process GO:0006783 22 15 0,000 0,0186971 0,03376577 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,0186971 0,03374009 ! lymphocyte homeostasis GO:0002260 29 15 0,000 0,0186971 0,03371445 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,0186971 0,03368885 ! cilium assembly GO:0042384 22 15 0,000 0,0186971 0,03366329 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,0186971 0,03363777 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,0186971 0,03361229 ! peptide hormone processing GO:0016486 23 15 0,000 0,0186971 0,03358684 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,0186971 0,03356144 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,01993157 0,03575027 ! bone remodeling GO:0046849 24 16 0,000 0,01993157 0,03572327 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,01993157 0,03569631 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,01993157 0,03566939 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,01993157 0,03564251 ! bile acid metabolic process GO:0008206 23 16 0,000 0,01993157 0,03561567 ! axis specification GO:0009798 26 16 0,000 0,01993157 0,03558887 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,01993157 0,03556211 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,01993157 0,03553539 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01993157 0,03550872 ! centrosome cycle GO:0007098 18 16 0,000 0,01993157 0,03548208 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,01993157 0,03545548 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,01993157 0,03542892 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,01993157 0,0354024 ! cellular response to starvation GO:0009267 26 16 0,000 0,01993157 0,03537592 ! DNA integration GO:0015074 25 16 0,000 0,01993157 0,03534948 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,01993157 0,03532308 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,01993157 0,03529672 ! regulation of exocytosis GO:0017157 28 16 0,000 0,01993157 0,0352704 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,01993157 0,03524412 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,01993157 0,03521788 ! regulation of vasodilation GO:0042312 26 16 0,000 0,01993157 0,03519167 ! DNA replication initiation GO:0006270 26 16 0,000 0,01993157 0,03516551 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,01993157 0,03513938 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,01993157 0,0351133 ! neuron recognition GO:0008038 27 16 0,000 0,01993157 0,03508725 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,01993157 0,03506124 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,01993157 0,03503527 ! G1 phase GO:0051318 28 16 0,000 0,01993157 0,03500933 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,01993157 0,03498344 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01993157 0,03495758 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,01993157 0,03493176 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,01993157 0,03490599 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,01993157 0,03488024 ! NADP metabolic process GO:0006739 22 16 0,000 0,01993157 0,03485454 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,01993157 0,03482887 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,01993157 0,03480324 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,01993157 0,03477765 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,01993157 0,0347521 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01993157 0,03472659 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,01993157 0,03470111 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,01993157 0,03467567 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,01993157 0,03465026 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,01993157 0,0346249 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,01993157 0,03459957 ! defense response to virus GO:0051607 28 16 0,000 0,01993157 0,03457428 ! peptide hormone secretion GO:0030072 26 16 0,000 0,01993157 0,03454902 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,02116454 0,03665946 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,02116454 0,03663272 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,02116454 0,03660602 ! zinc ion transport GO:0006829 22 17 0,000 0,02116454 0,03657936 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02116454 0,03655274 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,02116454 0,03652616 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,02116454 0,03649961 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,02116454 0,0364731 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,02116454 0,03644664 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,02116454 0,03642021 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,02116454 0,03639381 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,02116454 0,03636746 ! adult walking behavior GO:0007628 30 17 0,000 0,02116454 0,03634115 ! patterning of blood vessels GO:0001569 27 17 0,000 0,02116454 0,03631487 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,02116454 0,03628863 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,02116454 0,03626243 GO:0042744|hydrogen peroxide catabolic process, ! retinoid metabolic process GO:0001523 22 17 0,000 0,02116454 0,03623626 GO:0016101|diterpenoid metabolic process, ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,02116454 0,03621014 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,02116454 0,03618405 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02116454 0,036158 ! protein polyubiquitination GO:0000209 31 17 0,000 0,02116454 0,03613199 ! cerebral cortex development GO:0021987 34 17 0,000 0,02116454 0,03610601 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,02116454 0,03608007 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02116454 0,03605417 ! fructose metabolic process GO:0006000 24 17 0,000 0,02116454 0,03602831 ! membrane budding GO:0006900 30 17 0,000 0,02116454 0,03600248 ! neuromuscular junction development GO:0007528 25 17 0,000 0,02116454 0,03597669 ! L-amino acid transport GO:0015807 27 17 0,000 0,02116454 0,03595094 ! regulation of protein binding GO:0043393 29 17 0,000 0,02116454 0,03592522 ! peptide secretion GO:0002790 30 17 0,000 0,02116454 0,03589954 ! stem cell differentiation GO:0048863 40 17 0,000 0,02116454 0,0358739 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02116454 0,0358483 ! intermediate filament-based process GO:0045103 29 17 0,000 0,02116454 0,03582273 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,02116454 0,03579719 ! diencephalon development GO:0021536 27 17 0,000 0,02116454 0,0357717 ! oogenesis GO:0048477 25 17 0,000 0,02116454 0,03574624 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,02116454 0,03572081 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,02116454 0,03569543 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02116454 0,03567007 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,02116454 0,03564476 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,02116454 0,03561948 ! steroid catabolic process GO:0006706 24 17 0,000 0,02116454 0,03559423 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,02116454 0,03556902 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,02116454 0,03554385 ! nerve development GO:0021675 20 17 0,000 0,02116454 0,03551872 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,02116454 0,03549361 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,02116454 0,03546855 ! protein secretion GO:0009306 32 18 0,000 0,02239603 0,03750585 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,02239603 0,0374794 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,02239603 0,03745298 ! negative regulation of defense response GO:0031348 21 18 0,000 0,02239603 0,03742661 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,02239603 0,03740027 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,02239603 0,03737397 ! metencephalon development GO:0022037 25 18 0,000 0,02239603 0,0373477 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,02239603 0,03732148 ! hormone secretion GO:0046879 28 18 0,000 0,02239603 0,03729529 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,02239603 0,03726913 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,02239603 0,03724302 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,02239603 0,03721693 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02239603 0,03719089 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,02239603 0,03716488 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,02239603 0,03713891 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02239603 0,03711298 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,02239603 0,03708708 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,02239603 0,03706122 ! glial cell development GO:0021782 31 18 0,000 0,02239603 0,03703539 ! keratinization GO:0031424 19 18 0,000 0,02239603 0,0370096 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,02239603 0,03698384 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,02239603 0,03695812 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,02239603 0,03693244 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,02239603 0,03690679 ! vacuolar transport GO:0007034 26 18 0,000 0,02239603 0,03688118 ! pigmentation during development GO:0048066 35 18 0,000 0,02239603 0,03685561 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,02239603 0,03683006 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,02239603 0,03680456 ! fucose metabolic process GO:0006004 27 18 0,000 0,02239603 0,03677909 ! actin filament bundle formation GO:0051017 30 18 0,000 0,02239603 0,03675365 ! body fluid secretion GO:0007589 27 18 0,000 0,02239603 0,03672825 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,02239603 0,03670289 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,02239603 0,03667756 ! negative regulation of immune response GO:0050777 33 18 0,000 0,02239603 0,03665226 ! heart process GO:0003015 32 18 0,000 0,02239603 0,036627 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,02239603 0,03660178 ! sensory perception of pain GO:0019233 26 18 0,000 0,02239603 0,03657659 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,02239603 0,03655143 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,02239603 0,03652631 ! somitogenesis GO:0001756 25 18 0,000 0,02239603 0,03650122 ! neural crest cell migration GO:0001755 28 18 0,000 0,02239603 0,03647617 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,02239603 0,03645115 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,02239603 0,03642617 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,02239603 0,03640122 ! synaptogenesis GO:0007416 28 18 0,000 0,02239603 0,03637631 ! cell-cell junction organization GO:0045216 28 18 0,000 0,02239603 0,03635142 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02239603 0,03632658 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,02239603 0,03630176 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,02239603 0,03627698 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,02239603 0,03625224 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,02239603 0,03622753 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,02239603 0,03620285 ! gut development GO:0048565 29 18 0,000 0,02239603 0,0361782 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,02239603 0,03615359 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,02239603 0,03612902 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,02239603 0,03610447 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,02362603 0,03806149 ! positive regulation of translation GO:0045727 29 19 0,000 0,02362603 0,03803567 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,02362603 0,03800988 ! glycerol metabolic process GO:0006071 22 19 0,000 0,02362603 0,03798413 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,02362603 0,03795841 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,02362603 0,03793273 ! endothelial cell migration GO:0043542 24 19 0,000 0,02362603 0,03790708 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,02362603 0,03788147 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,02362603 0,03785589 ! memory GO:0007613 28 19 0,000 0,02362603 0,03783035 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,02362603 0,03780484 ! pancreas development GO:0031016 27 19 0,000 0,02362603 0,03777936 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,02362603 0,03775392 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,02362603 0,03772851 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,02362603 0,03770314 ! central nervous system neuron development GO:0021954 33 19 0,000 0,02362603 0,0376778 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,02362603 0,0376525 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,02362603 0,03762723 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,02362603 0,03760199 ! heme metabolic process GO:0042168 29 19 0,000 0,02362603 0,03757679 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,02362603 0,03755162 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,02362603 0,03752649 ! response to fungus GO:0009620 21 19 0,000 0,02362603 0,03750139 ! peptide cross-linking GO:0018149 35 19 0,000 0,02362603 0,03747632 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,02362603 0,03745128 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,02362603 0,03742628 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,02362603 0,03740132 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,02362603 0,03737638 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,02362603 0,03735148 ! vitamin transport GO:0051180 26 19 0,000 0,02362603 0,03732661 ! sarcomere organization GO:0045214 26 19 0,000 0,02362603 0,03730178 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,02362603 0,03727698 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,02362603 0,03725221 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,02362603 0,03722747 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,02362603 0,03720277 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,02362603 0,0371781 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,02362603 0,03715346 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,02485455 0,03905949 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,02485455 0,03903364 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,02485455 0,03900783 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,02485455 0,03898205 ! lipid phosphorylation GO:0046834 28 20 0,000 0,02485455 0,0389563 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,02485455 0,03893059 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,02485455 0,03890491 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,02485455 0,03887926 ! response to alkaloid GO:0043279 34 20 0,000 0,02485455 0,03885365 ! sensory perception of taste GO:0050909 26 20 0,000 0,02485455 0,03882807 ! response to retinoic acid GO:0032526 27 20 0,000 0,02485455 0,03880252 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,02485455 0,03877701 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,02485455 0,03875154 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,02485455 0,03872609 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,02485455 0,03870068 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,02485455 0,0386753 ! sex determination GO:0007530 32 20 0,000 0,02485455 0,03864996 ! plasma membrane fusion GO:0045026 24 20 0,000 0,02485455 0,03862465 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,02485455 0,03859937 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,02485455 0,03857412 ! cytolysis GO:0019835 21 20 0,000 0,02485455 0,03854891 ! renal system process GO:0003014 35 20 0,000 0,02485455 0,03852373 ! vasodilation GO:0042311 36 20 0,000 0,02485455 0,03849859 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,02485455 0,03847347 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,02485455 0,03844839 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,02485455 0,03842335 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,02485455 0,03839833 ! hormone transport GO:0009914 30 20 0,000 0,02485455 0,03837335 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,02485455 0,0383484 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,02485455 0,03832348 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,02485455 0,0382986 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,02485455 0,03827374 ! sperm-egg recognition GO:0035036 24 20 0,000 0,02485455 0,03824892 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,02485455 0,03822413 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,02485455 0,03819938 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,02608158 0,04005927 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,02608158 0,04003336 ! positive regulation of fibroblast proliferation GO:0048146 30 21 0,000 0,02608158 0,04000749 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02608158 0,03998164 ! positive regulation of ossification GO:0045778 34 21 0,000 0,02608158 0,03995583 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 0,000 0,02608158 0,03993005 ! iron ion transport GO:0006826 49 21 0,000 0,02608158 0,03990431 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,02608158 0,0398786 ! microtubule-based transport GO:0010970 41 21 0,000 0,02608158 0,03985292 ! vesicle docking GO:0048278 28 21 0,000 0,02608158 0,03982727 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,02608158 0,03980166 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,02608158 0,03977608 ! response to ethanol GO:0045471 38 21 0,000 0,02608158 0,03975053 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,02608158 0,03972502 ! smooth muscle contraction GO:0006939 39 21 0,000 0,02608158 0,03969954 ! glutamine metabolic process GO:0006541 29 21 0,000 0,02608158 0,03967409 ! response to vitamin A GO:0033189 28 21 0,000 0,02608158 0,03964867 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,02608158 0,03962329 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,02608158 0,03959794 ! response to starvation GO:0042594 35 21 0,000 0,02608158 0,03957262 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,02608158 0,03954734 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,02608158 0,03952208 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,02608158 0,03949686 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,02608158 0,03947167 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,02608158 0,03944651 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,02608158 0,03942139 ! visual learning GO:0008542 38 21 0,000 0,02608158 0,0393963 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 0,000 0,02608158 0,03937123 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,02608158 0,0393462 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,02608158 0,03932121 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02608158 0,03929624 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,02608158 0,03927131 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,02608158 0,0392464 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02608158 0,03922153 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,02608158 0,03919669 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,02608158 0,03917189 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02608158 0,03914711 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,02608158 0,03912236 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,02608158 0,03909765 ! embryonic pattern specification GO:0009880 34 22 0,000 0,02730712 0,04090897 ! regulation of cell killing GO:0031341 37 22 0,000 0,02730712 0,04088316 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,02730712 0,04085738 ! gluconeogenesis GO:0006094 26 22 0,000 0,02730712 0,04083164 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,02730712 0,04080592 ! viral genome replication GO:0019079 31 22 0,000 0,02730712 0,04078024 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,02730712 0,04075459 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,02730712 0,04072898 ! protein amino acid acylation GO:0043543 42 22 0,000 0,02730712 0,0407034 ! response to vitamin GO:0033273 31 22 0,000 0,02730712 0,04067784 ! molting cycle process GO:0022404 43 22 0,000 0,02730712 0,04065232 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,02730712 0,04062684 ! regeneration GO:0031099 37 22 0,000 0,02730712 0,04060138 ! phototransduction GO:0007602 29 22 0,000 0,02730712 0,04057596 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,02730712 0,04055057 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,02730712 0,04052521 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,02730712 0,04049988 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,02730712 0,04047458 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,02730712 0,04044932 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,02730712 0,04042408 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,02730712 0,04039888 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,02730712 0,04037371 ! pallium development GO:0021543 43 22 0,000 0,02730712 0,04034857 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,02730712 0,04032346 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,02730712 0,04029839 ! platelet activation GO:0030168 33 22 0,000 0,02730712 0,04027334 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,02730712 0,04024833 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,02730712 0,04022334 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,02730712 0,04019839 ! cell-cell recognition GO:0009988 28 22 0,000 0,02730712 0,04017347 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,02730712 0,04014858 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,02730712 0,04012372 ! neural tube closure GO:0001843 35 22 0,000 0,02730712 0,04009889 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,02730712 0,04007409 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,02730712 0,04004932 ! protein tetramerization GO:0051262 43 22 0,000 0,02730712 0,04002459 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,02853119 0,04179291 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,02853119 0,04176713 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,02853119 0,04174138 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,02853119 0,04171566 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,02853119 0,04168997 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,02853119 0,04166432 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,02853119 0,04163869 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,02853119 0,0416131 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,02853119 0,04158754 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,02853119 0,04156201 ! tube lumen formation GO:0035148 37 23 0,000 0,02853119 0,04153651 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,02853119 0,04151105 ! dendrite development GO:0016358 41 23 0,000 0,02853119 0,04148561 ! vasculogenesis GO:0001570 38 23 0,000 0,02853119 0,04146021 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,02853119 0,04143483 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,02853119 0,04140949 ! lysosome organization GO:0007040 41 23 0,000 0,02853119 0,04138418 ! digestive system process GO:0022600 35 23 0,000 0,02853119 0,0413589 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,02853119 0,04133365 ! vesicle targeting GO:0006903 35 23 0,000 0,02853119 0,04130843 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,02853119 0,04128324 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,02853119 0,04125808 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,02853119 0,04123296 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,02853119 0,04120786 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,02853119 0,0411828 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,02853119 0,04115776 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,02853119 0,04113276 ! membrane depolarization GO:0051899 40 23 0,000 0,02853119 0,04110778 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02853119 0,04108284 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,02853119 0,04105792 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,02853119 0,04103304 ! DNA modification GO:0006304 33 23 0,000 0,02853119 0,04100819 ! collagen fibril organization GO:0030199 50 23 0,000 0,02853119 0,04098336 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,02853119 0,04095857 ! cellular response to extracellular stimulus GO:0031668 37 23 0,000 0,02853119 0,04093381 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,02853119 0,04090907 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,02853119 0,04088437 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,02853119 0,0408597 ! positive regulation of B cell activation GO:0050871 36 23 0,000 0,02853119 0,04083505 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02853119 0,04081044 ! collagen catabolic process GO:0030574 29 23 0,000 0,02853119 0,04078585 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,02853119 0,0407613 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,02853119 0,04073677 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,02853119 0,04071228 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,02853119 0,04068781 ! blastocyst development GO:0001824 41 23 0,000 0,02853119 0,04066337 ! actin filament-based movement GO:0030048 37 23 0,000 0,02853119 0,04063897 ! protein stabilization GO:0050821 34 23 0,000 0,02853119 0,04061459 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,02975378 0,04232957 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,02975378 0,04230421 ! myelination GO:0042552 39 24 0,000 0,02975378 0,04227887 ! initiation of viral infection GO:0019059 47 24 0,000 0,02975378 0,04225357 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,02975378 0,0422283 ! leukocyte adhesion GO:0007159 49 24 0,000 0,02975378 0,04220306 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,02975378 0,04217785 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,02975378 0,04215267 ! visual behavior GO:0007632 42 24 0,000 0,02975378 0,04212752 ! spinal cord development GO:0021510 41 24 0,000 0,02975378 0,0421024 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,02975378 0,04207731 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,02975378 0,04205224 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,02975378 0,04202721 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,02975378 0,04200221 ! cell aging GO:0007569 38 24 0,000 0,02975378 0,04197724 ! osteoblast differentiation GO:0001649 43 24 0,000 0,02975378 0,0419523 ! response to toxin GO:0009636 38 24 0,000 0,02975378 0,04192739 ! primary neural tube formation GO:0014020 37 24 0,000 0,02975378 0,0419025 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,02975378 0,04187765 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,02975378 0,04185283 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,02975378 0,04182803 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,02975378 0,04180327 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,02975378 0,04177853 ! pentose metabolic process GO:0019321 33 24 0,000 0,02975378 0,04175383 ! immunoglobulin production GO:0002377 37 24 0,000 0,02975378 0,04172915 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,02975378 0,0417045 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,02975378 0,04167988 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,02975378 0,04165529 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,02975378 0,04163073 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,02975378 0,0416062 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,02975378 0,0415817 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,02975378 0,04155722 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,02975378 0,04153278 ! regulation of fibroblast proliferation GO:0048145 39 25 0,000 0,03097489 0,04321189 ! neuron fate commitment GO:0048663 38 25 0,000 0,03097489 0,0431865 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,03097489 0,04316114 ! superoxide metabolic process GO:0006801 33 25 0,000 0,03097489 0,04313581 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,03097489 0,04311051 GO:0050908|detection of light stimulus involved in visual perception, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,03097489 0,04308524 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,03097489 0,04306 ! vacuole organization GO:0007033 43 25 0,000 0,03097489 0,04303479 ! receptor metabolic process GO:0043112 40 25 0,000 0,03097489 0,04300961 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,03097489 0,04298445 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,03097489 0,04295933 ! regulation of behavior GO:0050795 45 25 0,000 0,03097489 0,04293424 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,03097489 0,04290917 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,03097489 0,04288414 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,03097489 0,04285913 ! negative regulation of phosphorylation GO:0042326 46 25 0,000 0,03097489 0,04283416 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03097489 0,04280921 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,03097489 0,04278429 ! leukocyte homeostasis GO:0001776 40 25 0,000 0,03097489 0,0427594 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,03097489 0,04273454 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,03097489 0,04270971 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,03097489 0,04268491 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,03097489 0,04266014 ! regulation of amine transport GO:0051952 44 25 0,000 0,03097489 0,04263539 ! liver development GO:0001889 44 25 0,000 0,03097489 0,04261068 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,03219453 0,04426281 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,03219453 0,04423718 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,03219453 0,04421158 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,03219453 0,04418601 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,03219453 0,04416047 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,03219453 0,04413496 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,03219453 0,04410948 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,03219453 0,04408402 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,03219453 0,0440586 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,03219453 0,04403321 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,03219453 0,04400784 ! sperm motility GO:0030317 31 26 0,000 0,03219453 0,04398251 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,03219453 0,0439572 ! male gonad development GO:0008584 39 26 0,000 0,03219453 0,04393192 ! neural crest cell development GO:0014032 44 26 0,000 0,03219453 0,04390667 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,03219453 0,04388145 ! cell fate determination GO:0001709 54 26 0,000 0,03219453 0,04385626 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,03219453 0,0438311 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,03219453 0,04380597 ! detection of visible light GO:0009584 33 26 0,000 0,03219453 0,04378087 ! spermatid development GO:0007286 40 26 0,000 0,03219453 0,04375579 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,03219453 0,04373075 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,03219453 0,04370573 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,03219453 0,04368074 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,03219453 0,04365578 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03341269 0,04528173 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,03341269 0,04525589 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,03341269 0,04523007 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! membrane docking GO:0022406 40 27 0,000 0,03341269 0,04520428 ! circadian rhythm GO:0007623 44 27 0,000 0,03341269 0,04517852 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,03341269 0,0451528 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,03341269 0,0451271 ! autophagy GO:0006914 36 27 0,000 0,03341269 0,04510143 ! myofibril assembly GO:0030239 40 27 0,000 0,03341269 0,04507579 GO:0055002|striated muscle cell development, ! negative regulation of phosphorus metabolic process GO:0010563 51 27 0,000 0,03341269 0,04505018 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,03341269 0,04502459 ! peptide transport GO:0015833 46 27 0,000 0,03341269 0,04499904 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,03341269 0,04497352 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,03341269 0,04494802 ! negative regulation of cell development GO:0010721 67 27 0,000 0,03341269 0,04492256 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,03341269 0,04489712 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,03341269 0,04487171 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,03341269 0,04484633 ! detection of light stimulus GO:0009583 35 27 0,000 0,03341269 0,04482098 ! glutathione metabolic process GO:0006749 35 27 0,000 0,03341269 0,04479566 ! lipid oxidation GO:0034440 39 27 0,000 0,03341269 0,04477036 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,03341269 0,0447451 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,03341269 0,04471986 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,03341269 0,04469465 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,03462938 0,04629607 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,03462938 0,04627 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,03462938 0,04624396 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,03462938 0,04621795 ! regulation of pH GO:0006885 40 28 0,000 0,03462938 0,04619197 ! catechol metabolic process GO:0009712 46 28 0,000 0,03462938 0,04616602 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,03462938 0,0461401 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,03462938 0,04611421 ! iron ion homeostasis GO:0055072 49 28 0,000 0,03462938 0,04608834 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,03462938 0,04606251 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,03462938 0,0460367 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,03462938 0,04601093 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,03462938 0,04598518 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,03462938 0,04595946 ! regulation of coagulation GO:0050818 42 28 0,000 0,03462938 0,04593377 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,0358446 0,04751912 ! phenol metabolic process GO:0018958 47 29 0,000 0,0358446 0,04749259 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,0358446 0,04746609 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,0358446 0,04743962 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,0358446 0,04741317 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,0358446 0,04738676 ! cholesterol transport GO:0030301 48 29 0,000 0,0358446 0,04736038 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,0358446 0,04733402 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,0358446 0,04730769 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,0358446 0,0472814 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,0358446 0,04725513 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,0358446 0,04722889 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,0358446 0,04720268 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,0358446 0,0471765 ! response to ionizing radiation GO:0010212 55 29 0,000 0,0358446 0,04715035 ! muscle cell development GO:0055001 42 29 0,000 0,0358446 0,04712423 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,0358446 0,04709814 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,0358446 0,04707207 ! mesoderm formation GO:0001707 52 29 0,000 0,0358446 0,04704604 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,0358446 0,04702003 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,0358446 0,04699405 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,0358446 0,0469681 ! ensheathment of neurons GO:0007272 48 29 0,000 0,0358446 0,04694218 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,0358446 0,04691629 ! spermatid differentiation GO:0048515 45 29 0,000 0,0358446 0,04689043 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,0358446 0,04686459 ! neural tube formation GO:0001841 46 29 0,000 0,0358446 0,04683878 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,03705835 0,04839816 ! organic anion transport GO:0015711 50 30 0,000 0,03705835 0,04837154 ! cell junction assembly GO:0034329 65 30 0,000 0,03705835 0,04834495 ! acute-phase response GO:0006953 49 30 0,000 0,03705835 0,04831839 ! segmentation GO:0035282 43 30 0,000 0,03705835 0,04829185 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,03705835 0,04826535 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,03705835 0,04823887 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,03705835 0,04821243 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,03705835 0,04818601 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,03705835 0,04815962 ! ceramide metabolic process GO:0006672 47 30 0,000 0,03705835 0,04813326 ! formation of primary germ layer GO:0001704 54 30 0,000 0,03705835 0,04810693 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,03705835 0,04808063 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,03705835 0,04805435 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,03705835 0,04802811 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,03705835 0,04800189 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,03705835 0,0479757 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,03705835 0,04794954 ! response to heat GO:0009408 43 30 0,000 0,03705835 0,04792341 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,03705835 0,04789731 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,03827063 0,04943724 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,03827063 0,04941035 ! post-embryonic development GO:0009791 50 31 0,000 0,03827063 0,04938348 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,03827063 0,04935664 ! regulation of innate immune response GO:0045088 42 31 0,000 0,03827063 0,04932983 ! ovulation cycle process GO:0022602 46 31 0,000 0,03827063 0,04930305 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,03827063 0,0492763 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,03827063 0,04924957 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,03827063 0,04922288 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,03827063 0,04919622 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,03827063 0,04916958 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,03827063 0,04914297 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,03827063 0,0491164 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,03827063 0,04908985 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,03827063 0,04906333 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,03827063 0,04903683 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,03827063 0,04901037 ! tissue homeostasis GO:0001894 45 31 0,000 0,03827063 0,04898394 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,03948145 0,05050646 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,03948145 0,05047925 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,03948145 0,05045207 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,03948145 0,05042491 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,03948145 0,05039779 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,03948145 0,05037069 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,03948145 0,05034363 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,03948145 0,05031659 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,03948145 0,05028958 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,03948145 0,0502626 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,03948145 0,05023565 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,03948145 0,05020873 ! telencephalon development GO:0021537 59 32 0,000 0,03948145 0,05018184 ! ovulation cycle GO:0042698 48 32 0,000 0,03948145 0,05015497 ! cofactor catabolic process GO:0051187 52 32 0,000 0,03948145 0,05012814 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,03948145 0,05010133 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,03948145 0,05007455 ! placenta development GO:0001890 45 32 0,000 0,03948145 0,0500478 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,03948145 0,05002108 ! vesicle localization GO:0051648 50 32 0,000 0,03948145 0,04999439 ! regulation of muscle development GO:0048634 52 33 0,000 0,04069081 0,05149829 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,04069081 0,05147084 ! negative regulation of secretion GO:0051048 53 33 0,000 0,04069081 0,05144342 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,04069081 0,05141602 ! glial cell differentiation GO:0010001 65 33 0,000 0,04069081 0,05138866 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,04069081 0,05136132 ! sister chromatid segregation GO:0000819 48 33 0,000 0,04069081 0,05133402 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,04069081 0,05130674 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,04069081 0,0512795 ! spindle organization GO:0007051 39 33 0,000 0,04069081 0,05125228 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,04069081 0,05122509 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,04069081 0,05119793 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,04069081 0,05117079 ! protein targeting to membrane GO:0006612 63 33 0,000 0,04069081 0,05114369 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,04069081 0,05111662 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,04069081 0,05108957 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,04069081 0,05106255 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,04069081 0,05103557 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,04069081 0,05100861 ! cytokine production GO:0001816 49 33 0,000 0,04069081 0,05098167 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,04069081 0,05095477 ! RNA modification GO:0009451 43 33 0,000 0,04069081 0,0509279 ! regulation of B cell activation GO:0050864 55 33 0,000 0,04069081 0,05090105 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,04069081 0,05087423 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,0418987 0,05235683 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,0418987 0,05232927 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,0418987 0,05230175 ! actomyosin structure organization GO:0031032 48 34 0,000 0,0418987 0,05227425 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,0418987 0,05224678 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,0418987 0,05221934 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,0418987 0,05219193 ! positive regulation of cell development GO:0010720 58 34 0,000 0,0418987 0,05216454 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,0418987 0,05213719 ! cell fate specification GO:0001708 49 34 0,000 0,0418987 0,05210986 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 0,000 0,0418987 0,05208257 ! peripheral nervous system development GO:0007422 58 34 0,000 0,0418987 0,0520553 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,0418987 0,05202806 ! adult locomotory behavior GO:0008344 54 34 0,000 0,0418987 0,05200085 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,0418987 0,05197367 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,04310514 0,05344226 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,04310514 0,05341435 ! collagen metabolic process GO:0032963 47 35 0,000 0,04310514 0,05338648 ! cell junction organization GO:0034330 72 35 0,000 0,04310514 0,05335863 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,04310514 0,05333081 ! metanephros development GO:0001656 61 35 0,000 0,04310514 0,05330302 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,04310514 0,05327525 ! female gonad development GO:0008585 55 35 0,000 0,04310514 0,05324752 ! lipid homeostasis GO:0055088 63 35 0,000 0,04310514 0,05321982 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,04310514 0,05319214 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,04310514 0,0531645 ! hindbrain development GO:0030902 56 35 0,000 0,04310514 0,05313688 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,04310514 0,05310929 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,04310514 0,05308173 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,04310514 0,0530542 ! cytokinesis GO:0000910 57 35 0,000 0,04310514 0,05302669 ! embryonic organ development GO:0048568 53 35 0,000 0,04310514 0,05299922 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,04310514 0,05297177 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,04310514 0,05294435 ! protein homooligomerization GO:0051260 59 35 0,000 0,04310514 0,05291696 ! meiosis I GO:0007127 61 36 0,000 0,04431011 0,05436809 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,04431011 0,05434 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,04431011 0,05431193 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,04431011 0,05428389 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,04431011 0,05425588 ! spliceosome assembly GO:0000245 65 36 0,000 0,04431011 0,0542279 ! mismatch repair GO:0006298 42 36 0,000 0,04431011 0,05419995 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,04431011 0,05417202 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,04431011 0,05414413 ! regulation of proteolysis GO:0030162 53 36 0,000 0,04431011 0,05411626 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,04431011 0,05408842 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,04431011 0,05406061 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,04431011 0,05403283 ! eye morphogenesis GO:0048592 64 36 0,000 0,04431011 0,05400508 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,04431011 0,05397736 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,04551363 0,055415 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,04551363 0,05538659 ! mammary gland development GO:0030879 73 37 0,000 0,04551363 0,0553582 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,04551363 0,05532984 ! ear morphogenesis GO:0042471 50 37 0,000 0,04551363 0,05530151 ! odontogenesis GO:0042476 60 37 0,000 0,04551363 0,05527321 ! negative regulation of binding GO:0051100 59 37 0,000 0,04551363 0,05524493 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,04551363 0,05521669 ! tissue remodeling GO:0048771 65 37 0,000 0,04551363 0,05518847 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,04551363 0,05516029 GO:0042593|glucose homeostasis, ! natural killer cell activation GO:0030101 45 37 0,000 0,04551363 0,05513213 ! polyol metabolic process GO:0019751 47 37 0,000 0,04551363 0,055104 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,04551363 0,0550759 ! glucan metabolic process GO:0044042 54 37 0,000 0,04551363 0,05504783 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,04671569 0,05647292 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,04671569 0,05644417 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,04671569 0,05641544 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,04671569 0,05638674 ! feeding behavior GO:0007631 50 38 0,000 0,04671569 0,05635808 ! organic ether metabolic process GO:0018904 51 38 0,000 0,04671569 0,05632944 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,04671569 0,05630083 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,04671569 0,05627225 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,04671569 0,0562437 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,04671569 0,05621518 ! ion transmembrane transport GO:0034220 58 38 0,000 0,04671569 0,05618669 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,04671569 0,05615823 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,04671569 0,05612979 ! neuron migration GO:0001764 59 38 0,000 0,04671569 0,05610139 ! maintenance of protein location GO:0045185 72 38 0,000 0,04671569 0,05607301 ! pigment metabolic process GO:0042440 66 38 0,000 0,04671569 0,05604466 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,04671569 0,05601634 ! mRNA catabolic process GO:0006402 58 39 0,000 0,0479163 0,05742696 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,0479163 0,05739797 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,0479163 0,05736901 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,0479163 0,05734008 ! neural tube development GO:0021915 58 39 0,000 0,0479163 0,05731118 ! regulation of protein stability GO:0031647 58 39 0,000 0,0479163 0,05728231 ! female gamete generation GO:0007292 50 39 0,000 0,0479163 0,05725347 ! aerobic respiration GO:0009060 56 39 0,000 0,0479163 0,05722465 ! positive regulation of leukocyte proliferation GO:0070665 64 39 0,000 0,0479163 0,05719587 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,0479163 0,05716711 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,04911546 0,05856834 ! Notch signaling pathway GO:0007219 64 40 0,000 0,04911546 0,05853892 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,04911546 0,05850953 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,04911546 0,05848018 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,04911546 0,05845085 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,04911546 0,05842155 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,04911546 0,05839228 ! phagocytosis GO:0006909 65 40 0,000 0,04911546 0,05836304 ! mesenchymal cell development GO:0014031 70 40 0,000 0,04911546 0,05833383 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,04911546 0,05830465 ! B cell differentiation GO:0030183 70 40 0,000 0,04911546 0,0582755 ! pigmentation GO:0043473 81 40 0,000 0,04911546 0,05824637 ! developmental growth GO:0048589 70 40 0,000 0,04911546 0,05821728 ! synapse organization GO:0050808 61 40 0,000 0,04911546 0,05818821 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,05031317 0,05957742 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,05031317 0,05954771 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,05031317 0,05951802 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,05031317 0,05948837 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,05031317 0,05945874 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,05031317 0,05942914 ! cell growth GO:0016049 71 41 0,000 0,05031317 0,05939958 ! maintenance of location in cell GO:0051651 77 41 0,000 0,05031317 0,05937004 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,05150943 0,06075143 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,05150943 0,06072125 ! learning GO:0007612 75 42 0,000 0,05150943 0,0606911 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,05150943 0,06066098 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,05150943 0,06063089 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,05150943 0,06060083 ! gliogenesis GO:0042063 85 42 0,000 0,05150943 0,0605708 ! endosome transport GO:0016197 74 42 0,000 0,05150943 0,0605408 ! male sex differentiation GO:0046661 62 42 0,000 0,05150943 0,06051083 ! double-strand break repair GO:0006302 75 42 0,000 0,05150943 0,06048089 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,05150943 0,06045098 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,05150943 0,0604211 ! mitochondrial transport GO:0006839 66 43 0,000 0,05270424 0,06179208 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,05270424 0,06176156 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,05270424 0,06173108 ! regulation of tube size GO:0035150 69 43 0,000 0,05270424 0,06170063 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,05270424 0,0616702 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,05270424 0,06163981 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,05270424 0,06160944 ! T cell differentiation GO:0030217 78 43 0,000 0,05270424 0,06157911 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,05270424 0,0615488 ! amino acid activation GO:0043038 61 43 0,000 0,05270424 0,06151853 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,05270424 0,06148828 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,05389761 0,06284965 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,05389761 0,06281878 ! cellular component disassembly GO:0022411 66 44 0,000 0,05389761 0,06278794 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,05389761 0,06275713 ! peptide metabolic process GO:0006518 64 44 0,000 0,05389761 0,06272635 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,05389761 0,0626956 ! inner ear development GO:0048839 66 44 0,000 0,05389761 0,06266489 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,05389761 0,0626342 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,05389761 0,06260354 ! chromatin remodeling GO:0006338 73 44 0,000 0,05389761 0,06257291 ! biopolymer methylation GO:0043414 67 44 0,000 0,05389761 0,06254231 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,05389761 0,06251175 ! JNK cascade GO:0007254 66 44 0,000 0,05389761 0,06248121 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,05389761 0,0624507 ! regulation of cell shape GO:0008360 83 44 0,000 0,05389761 0,06242022 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,05508954 0,0637695 ! positive regulation of binding GO:0051099 67 45 0,000 0,05508954 0,06373841 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,05508954 0,06370734 ! regulation of ion transport GO:0043269 60 45 0,000 0,05508954 0,06367631 ! glucose transport GO:0015758 60 45 0,000 0,05508954 0,06364531 ! neuromuscular process GO:0050905 89 45 0,000 0,05508954 0,06361434 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,05508954 0,0635834 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,05508954 0,06355249 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,05628002 0,06489431 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,05628002 0,06486279 ! regulation of action potential GO:0001508 80 46 0,000 0,05628002 0,0648313 ! hexose transport GO:0008645 62 46 0,000 0,05628002 0,06479985 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,05628002 0,06476842 ! excretion GO:0007588 72 46 0,000 0,05628002 0,06473703 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,05628002 0,06470566 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,05628002 0,06467433 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,05628002 0,06464302 ! positive regulation of defense response GO:0031349 70 47 0,000 0,05746906 0,06597682 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,05746906 0,06594492 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,05746906 0,06591304 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,05746906 0,0658812 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,05746906 0,06584939 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,05746906 0,06581761 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,05865667 0,06714533 ! viral infectious cycle GO:0019058 80 48 0,000 0,05865667 0,06711296 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,05865667 0,06708061 ! leukocyte migration GO:0050900 76 48 0,000 0,05865667 0,0670483 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,05865667 0,06701602 ! striated muscle contraction GO:0006941 78 48 0,000 0,05865667 0,06698377 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,05865667 0,06695155 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,05865667 0,06691936 ! tRNA processing GO:0008033 56 48 0,000 0,05865667 0,06688721 ! cell maturation GO:0048469 69 48 0,000 0,05865667 0,06685508 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,05865667 0,06682298 ! vesicle organization GO:0016050 87 48 0,000 0,05865667 0,06679092 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,05865667 0,06675888 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,05984284 0,06807625 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,05984284 0,06804363 ! glycolysis GO:0006096 63 49 0,000 0,05984284 0,06801104 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,05984284 0,06797848 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,05984284 0,06794596 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,05984284 0,06791346 ! response to temperature stimulus GO:0009266 66 49 0,000 0,05984284 0,067881 ! endocrine system development GO:0035270 86 49 0,000 0,05984284 0,06784857 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,05984284 0,06781617 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,05984284 0,0677838 ! gastrulation GO:0007369 80 49 0,000 0,05984284 0,06775146 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,05984284 0,06771915 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,05984284 0,06768687 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,05984284 0,06765462 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,05984284 0,06762241 ! methylation GO:0032259 74 49 0,000 0,05984284 0,06759022 ! cell redox homeostasis GO:0045454 72 50 0,000 0,06102757 0,06889554 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,06102757 0,06886278 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,06102757 0,06883005 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,06102757 0,06879735 ! histone modification GO:0016570 81 50 0,000 0,06102757 0,06876468 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,06102757 0,06873205 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,06102757 0,06869944 ! regulation of mast cell proliferation GO:0070666 80 50 0,000 0,06102757 0,06866687 ! RNA catabolic process GO:0006401 77 51 0,000 0,06221087 0,06996512 ! chloride transport GO:0006821 78 51 0,000 0,06221087 0,06993197 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,06221087 0,06989886 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,06221087 0,06986578 ! regulation of ossification GO:0030278 82 51 0,000 0,06221087 0,06983273 ! heart morphogenesis GO:0003007 71 51 0,000 0,06221087 0,06979971 ! RNA elongation GO:0006354 67 51 0,000 0,06221087 0,06976673 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,06221087 0,06973377 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,06339274 0,07102501 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,06339274 0,07099149 ! regulation of DNA replication GO:0006275 88 52 0,000 0,06339274 0,070958 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,06339274 0,07092455 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,06339274 0,07089113 ! covalent chromatin modification GO:0016569 90 52 0,000 0,06339274 0,07085773 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,06339274 0,07082437 ! proton transport GO:0015992 78 52 0,000 0,06339274 0,07079104 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,06339274 0,07075775 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,06339274 0,07072448 ! transition metal ion transport GO:0000041 88 53 0,000 0,06457318 0,07200759 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,06457318 0,07197377 ! muscle fiber development GO:0048747 80 53 0,000 0,06457318 0,07193998 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,06457318 0,07190622 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,06457318 0,07187249 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,06457318 0,0718388 ! regulation of endocytosis GO:0030100 71 53 0,000 0,06457318 0,07180513 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,06457318 0,0717715 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,06457318 0,0717379 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,06457318 0,07170433 ! regulation of leukocyte proliferation GO:0070663 88 53 0,000 0,06457318 0,07167079 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! maintenance of location GO:0051235 94 53 0,000 0,06457318 0,07163728 ! hydrogen transport GO:0006818 81 54 0,000 0,06575219 0,07291119 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,06575219 0,07287713 ! regulation of mitosis GO:0007088 91 54 0,000 0,06575219 0,07284311 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,06575219 0,07280912 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,06575219 0,07277516 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,06575219 0,07274123 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,06575219 0,07270734 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,06575219 0,07267347 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,06575219 0,07263964 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,06575219 0,07260584 ! germ cell development GO:0007281 82 54 0,000 0,06575219 0,07257207 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,06575219 0,07253833 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,06575219 0,07250462 ! establishment of organelle localization GO:0051656 91 54 0,000 0,06575219 0,07247094 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,06692977 0,07373461 ! ear development GO:0043583 83 55 0,000 0,06692977 0,07370039 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,06692977 0,07366621 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,06692977 0,07363206 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,06692977 0,07359794 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,06692977 0,07356385 ! regulation of actin filament length GO:0030832 88 56 0,000 0,06810593 0,07482193 ! positive regulation of secretion GO:0051047 83 56 0,000 0,06810593 0,07478731 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,06810593 0,07475272 ! DNA catabolic process GO:0006308 71 56 0,000 0,06810593 0,07471816 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,06810593 0,07468363 ! adult behavior GO:0030534 90 56 0,000 0,06810593 0,07464913 ! cartilage development GO:0051216 84 56 0,000 0,06810593 0,07461467 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,06928067 0,07586665 ! mesoderm development GO:0007498 84 57 0,000 0,06928067 0,07583165 ! aging GO:0007568 91 57 0,000 0,06928067 0,07579669 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,06928067 0,07576176 ! single fertilization GO:0007338 67 57 0,000 0,06928067 0,07572686 ! regulation of cellular component size GO:0032535 90 58 0,000 0,07045398 0,07697389 ! lipid modification GO:0030258 82 58 0,000 0,07045398 0,07693847 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,07045398 0,07690308 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,07045398 0,07686772 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,07162587 0,07811038 ! viral reproductive process GO:0022415 99 59 0,000 0,07162587 0,0780745 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,07162587 0,07803866 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,07162587 0,07800284 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,07162587 0,07796706 ! cell projection assembly GO:0030031 90 59 0,000 0,07162587 0,07793131 ! glucose catabolic process GO:0006007 78 60 0,000 0,07279635 0,07916853 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,07279635 0,07913227 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,07279635 0,07909603 ! kidney development GO:0001822 101 60 0,000 0,07279635 0,07905983 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,07279635 0,07902367 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,07396541 0,08025602 ! carbohydrate transport GO:0008643 83 61 0,000 0,07396541 0,08021934 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,07396541 0,08018269 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,07513305 0,08141129 ! amino acid transport GO:0006865 97 62 0,000 0,07513305 0,08137413 ! activation of MAPK activity GO:0000187 95 62 0,000 0,07513305 0,08133701 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,07513305 0,08129992 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,07513305 0,08126287 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,07513305 0,08122584 ! detection of external stimulus GO:0009581 78 62 0,000 0,07513305 0,08118886 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,07513305 0,0811519 ! secondary metabolic process GO:0019748 95 62 0,000 0,07513305 0,08111498 ! gonad development GO:0008406 91 62 0,000 0,07513305 0,08107809 ! exocytosis GO:0006887 91 63 0,000 0,07629928 0,08229918 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,07629928 0,08226179 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,07629928 0,08222443 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,07629928 0,0821871 ! regulation of heart contraction GO:0008016 104 63 0,000 0,07629928 0,08214981 ! developmental maturation GO:0021700 90 63 0,000 0,07629928 0,08211256 ! actin filament organization GO:0007015 107 64 0,000 0,0774641 0,08332833 ! fertilization GO:0009566 79 64 0,000 0,0774641 0,08329058 ! viral reproduction GO:0016032 104 64 0,000 0,0774641 0,08325286 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,0774641 0,08321517 ! amine catabolic process GO:0009310 100 65 0,000 0,07862751 0,08442673 ! negative regulation of cell growth GO:0030308 123 65 0,000 0,07862751 0,08438854 ! camera-type eye development GO:0043010 103 65 0,000 0,07862751 0,08435039 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,07862751 0,08431228 ! regulation of lipase activity GO:0060191 117 65 0,000 0,07862751 0,0842742 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,07862751 0,08423615 ! organelle localization GO:0051640 105 65 0,000 0,07862751 0,08419814 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,07978951 0,08540392 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,07978951 0,08536542 ! sensory perception of smell GO:0007608 81 66 0,000 0,07978951 0,08532695 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,07978951 0,08528851 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,07978951 0,08525011 ! lung development GO:0030324 112 66 0,000 0,07978951 0,08521174 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,07978951 0,08517341 ! B cell activation GO:0042113 119 66 0,000 0,07978951 0,08513512 ! protein oligomerization GO:0051259 109 66 0,000 0,07978951 0,08509685 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,0809501 0,08629586 ! negative regulation of cell size GO:0045792 125 67 0,000 0,0809501 0,08625711 ! neurotransmitter transport GO:0006836 92 67 0,000 0,0809501 0,08621839 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,0809501 0,08617971 ! appendage morphogenesis GO:0035107 103 67 0,000 0,0809501 0,08614107 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,0809501 0,08610246 ! extracellular matrix organization GO:0030198 117 67 0,000 0,0809501 0,08606388 ! meiosis GO:0007126 110 68 0,000 0,08210928 0,0872572 GO:0051327|M phase of meiotic cell cycle, ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,08210928 0,08721814 ! defense response to bacterium GO:0042742 79 68 0,000 0,08210928 0,08717912 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,08210928 0,08714013 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,08210928 0,08710118 ! activation of immune response GO:0002253 93 68 0,000 0,08210928 0,08706226 ! appendage development GO:0048736 108 69 0,000 0,08326707 0,08825045 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,08326707 0,08821105 ! urogenital system development GO:0001655 114 69 0,000 0,08326707 0,08817169 ! meiotic cell cycle GO:0051321 111 69 0,000 0,08326707 0,08813236 ! hexose catabolic process GO:0019320 95 70 0,000 0,08442345 0,08931647 ! adaptive immune response GO:0002250 102 70 0,000 0,08442345 0,08927667 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,08557843 0,09045774 ! cell-matrix adhesion GO:0007160 133 71 0,000 0,08557843 0,09041746 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,08557843 0,09037722 ! axon guidance GO:0007411 116 71 0,000 0,08557843 0,09033702 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,08557843 0,09029685 ! response to drug GO:0042493 115 72 0,000 0,08673201 0,09147336 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,08673201 0,09143273 ! homeostasis of number of cells GO:0048872 109 72 0,000 0,08673201 0,09139213 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,08673201 0,09135156 ! respiratory system development GO:0060541 123 72 0,000 0,08673201 0,09131103 ! rhythmic process GO:0048511 113 72 0,000 0,08673201 0,09127054 ! regulation of immune effector process GO:0002697 121 72 0,000 0,08673201 0,09123008 ! learning or memory GO:0007611 132 73 0,000 0,0878842 0,09240106 ! humoral immune response GO:0006959 93 73 0,000 0,0878842 0,09236014 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,0878842 0,09231926 ! acute inflammatory response GO:0002526 107 74 0,000 0,08903499 0,09348674 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,08903499 0,09344539 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,08903499 0,09340408 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,08903499 0,0933628 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,08903499 0,09332157 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,08903499 0,09328036 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,09018438 0,09444287 ! inorganic anion transport GO:0015698 109 75 0,000 0,09018438 0,09440121 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,09018438 0,09435959 ! regulation of catabolic process GO:0009894 114 75 0,000 0,09018438 0,094318 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,09133239 0,09547654 ! cell-substrate adhesion GO:0031589 141 76 0,000 0,09133239 0,0954345 ! negative regulation of transport GO:0051051 122 77 0,000 0,092479 0,09659008 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,092479 0,09654759 ! response to nutrient GO:0007584 114 77 0,000 0,092479 0,09650513 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,092479 0,09646271 ! regulation of blood pressure GO:0008217 119 78 0,000 0,09362422 0,09761436 ! muscle cell differentiation GO:0042692 117 78 0,000 0,09362422 0,09757149 ! negative regulation of growth GO:0045926 140 78 0,000 0,09362422 0,09752866 ! amine transport GO:0015837 115 78 0,000 0,09362422 0,09748586 ! antigen processing and presentation GO:0019882 114 78 0,000 0,09362422 0,09744311 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,09476806 0,09859036 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,09591051 0,09973516 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,09591051 0,09969148 ! regulation of DNA binding GO:0051101 130 80 0,000 0,09591051 0,09964783 ! tube morphogenesis GO:0035239 140 80 0,000 0,09591051 0,09960422 ! eye development GO:0001654 130 80 0,000 0,09591051 0,09956065 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,09591051 0,09951711 ! protein ubiquitination GO:0016567 135 80 0,000 0,09591051 0,09947362 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,09591051 0,09943016 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,09591051 0,09938674 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,09591051 0,09934336 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,09591051 0,09930002 ! blood coagulation GO:0007596 129 81 0,000 0,09705158 0,10043759 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,09705158 0,10039381 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,09705158 0,10035006 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,09705158 0,10030635 ! response to hypoxia GO:0001666 155 81 0,000 0,09705158 0,10026269 ! regulation of protein transport GO:0051223 123 81 0,000 0,09705158 0,10021906 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,09819126 0,10135183 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,09819126 0,10130776 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,09819126 0,10126374 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,09819126 0,10121975 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,09932956 0,1023487 ! response to oxygen levels GO:0070482 160 83 0,000 0,09932956 0,10230427 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,09932956 0,10225989 ! regulation of lyase activity GO:0051339 147 83 0,000 0,09932956 0,10221555 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,09932956 0,10217124 ! positive regulation of lymphocyte activation GO:0051251 134 83 0,000 0,09932956 0,10212697 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,10046648 0,10325118 ! digestion GO:0007586 111 84 0,000 0,10046648 0,10320648 ! regulation of neurological system process GO:0031644 133 84 0,000 0,10046648 0,10316182 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,10046648 0,1031172 ! cellular respiration GO:0045333 119 85 0,000 0,10160203 0,10423762 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,10160203 0,10419257 ! T cell activation GO:0042110 154 85 0,000 0,10160203 0,10414757 ! sex differentiation GO:0007548 126 85 0,000 0,10160203 0,1041026 ! protein import into nucleus GO:0006606 145 85 0,000 0,10160203 0,10405767 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,10160203 0,10401278 ! alcohol catabolic process GO:0046164 119 86 0,000 0,1027362 0,1051285 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,10386899 0,10624186 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,10386899 0,10619609 ! regulation of defense response GO:0031347 135 87 0,000 0,10386899 0,10615035 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,10386899 0,10610466 ! tRNA metabolic process GO:0006399 110 87 0,000 0,10386899 0,106059 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,10386899 0,10601339 ! gland development GO:0048732 170 87 0,000 0,10386899 0,10596781 ! vitamin metabolic process GO:0006766 117 87 0,000 0,10386899 0,10592227 ! forebrain development GO:0030900 151 87 0,000 0,10386899 0,10587677 ! regulation of membrane potential GO:0042391 144 88 0,000 0,10500041 0,10698411 ! ossification GO:0001503 150 89 0,000 0,10613046 0,1080891 GO:0060348|bone development, ! nucleosome assembly GO:0006334 113 89 0,000 0,10613046 0,10804273 GO:0031497|chromatin assembly, ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,10725914 0,10914492 ! microtubule cytoskeleton organization GO:0000226 133 90 0,000 0,10725914 0,10909814 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,10725914 0,10905139 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,10725914 0,10900469 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,10725914 0,10895803 ! nuclear import GO:0051170 153 90 0,000 0,10725914 0,1089114 ! regulation of protein localization GO:0032880 141 90 0,000 0,10725914 0,10886482 ! positive regulation of cell activation GO:0050867 146 90 0,000 0,10725914 0,10881828 GO:0002696|positive regulation of leukocyte activation, ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,10838646 0,10991498 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,10838646 0,10986803 ! protein localization in nucleus GO:0034504 161 92 0,000 0,1095124 0,11096197 ! sterol metabolic process GO:0016125 136 92 0,000 0,1095124 0,11091461 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,11063698 0,11200578 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,11063698 0,11195802 ! rRNA processing GO:0006364 124 93 0,000 0,11063698 0,1119103 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,11063698 0,11186262 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,11063698 0,11181497 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,11063698 0,11176737 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,11063698 0,11171981 ! leukocyte differentiation GO:0002521 165 94 0,000 0,1117602 0,11280602 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,1117602 0,11275806 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,1117602 0,11271014 ! rRNA metabolic process GO:0016072 125 94 0,000 0,1117602 0,11266226 ! hormone metabolic process GO:0042445 135 94 0,000 0,1117602 0,11261442 ! protein processing GO:0016485 127 94 0,000 0,1117602 0,11256662 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,11288205 0,11364833 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,11288205 0,11360013 ! ATP metabolic process GO:0046034 150 96 0,000 0,11400255 0,11467912 ! nucleosome organization GO:0034728 126 96 0,000 0,11400255 0,11463053 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,11400255 0,11458198 ! female pregnancy GO:0007565 148 96 0,000 0,11400255 0,11453347 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,11512168 0,11560887 ! reproductive developmental process GO:0003006 149 97 0,000 0,11512168 0,11555996 ! response to virus GO:0009615 141 98 0,000 0,11623946 0,11663266 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,11623946 0,11658337 ! regulation of T cell activation GO:0050863 155 98 0,000 0,11623946 0,11653411 ! regulation of binding GO:0051098 164 99 0,000 0,11735589 0,11760368 ! electron transport chain GO:0022900 135 99 0,000 0,11735589 0,11755404 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,11735589 0,11750444 ! cell fate commitment GO:0045165 165 99 0,000 0,11735589 0,11745488 ! positive regulation of immune response GO:0050778 143 99 0,000 0,11735589 0,11740536 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,11847096 0,11847096