pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/6134-7-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 4,000 5,015E-09 1,83E-05 ! interphase of mitotic cell cycle GO:0051329 100 81 4,000 5,333E-08 9,727E-05 ! interphase GO:0051325 103 83 4,000 6,033E-08 7,336E-05 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 1,032E-07 9,416E-05 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 3,000 2,479E-07 1,809E-04 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 2,000 6,677E-07 4,06E-04 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 2,000 1,026E-06 5,344E-04 ! response to calcium ion GO:0051592 34 31 2,000 8,128E-06 3,707E-03 ! microtubule organizing center part GO:0044450 46 32 2,000 8,962E-06 3,633E-03 ! DNA-directed RNA polymerase activity GO:0003899 49 38 2,000 1,517E-05 5,532E-03 GO:0034062|RNA polymerase activity, ! cytosolic large ribosomal subunit GO:0022625 43 38 2,000 1,517E-05 5,029E-03 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 1,000 1,572E-05 4,778E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 1,000 1,572E-05 4,41E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! positive regulation of viral reproduction GO:0048524 5 5 1,000 1,572E-05 4,095E-03 ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 1,572E-05 3,822E-03 ! induction of apoptosis by intracellular signals GO:0008629 56 41 2,000 1,912E-05 4,358E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 2,355E-05 5,055E-03 ! DNA topoisomerase activity GO:0003916 6 6 1,000 2,355E-05 4,774E-03 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 2,000 2,369E-05 4,548E-03 ! response to UV GO:0009411 59 45 2,000 2,536E-05 4,626E-03 ! RNA elongation GO:0006354 52 47 2,000 2,893E-05 5,026E-03 ! regulation of DNA repair GO:0006282 19 7 1,000 3,295E-05 5,464E-03 ! DNA topological change GO:0006265 7 7 1,000 3,295E-05 5,226E-03 ! DNA ligation GO:0006266 8 7 1,000 3,295E-05 5,009E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 1,000 3,295E-05 4,808E-03 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 1,000 4,39E-05 6,16E-03 ! positive regulation of protein ubiquitination GO:0031398 17 8 1,000 4,39E-05 5,931E-03 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 1,000 4,39E-05 5,72E-03 ! postreplication repair GO:0006301 19 8 1,000 4,39E-05 5,522E-03 ! chromosome segregation GO:0007059 92 57 2,000 5,177E-05 6,295E-03 ! large ribosomal subunit GO:0015934 64 58 2,000 5,454E-05 6,419E-03 ! gamma-tubulin complex GO:0000930 19 9 1,000 5,64E-05 6,429E-03 ! response to metal ion GO:0010038 65 60 2,000 6,039E-05 6,676E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 2,000 6,346E-05 6,809E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 2,000 6,663E-05 6,945E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 1,000 7,044E-05 7,138E-03 ! adult heart development GO:0007512 14 10 1,000 7,044E-05 6,945E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 1,000 7,044E-05 6,763E-03 ! response to inorganic substance GO:0010035 71 65 2,000 7,676E-05 7,18E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 2,000 7,676E-05 7,001E-03 ! protein kinase regulator activity GO:0019887 74 66 2,000 8,035E-05 7,149E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 2,000 8,404E-05 7,3E-03 ! centriole GO:0005814 11 11 1,000 8,603E-05 7,299E-03 ! regulation of viral genome replication GO:0045069 13 11 1,000 8,603E-05 7,133E-03 ! histone deacetylase binding GO:0042826 11 11 1,000 8,603E-05 6,974E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 8,603E-05 6,823E-03 ! protein kinase C binding GO:0005080 11 11 1,000 8,603E-05 6,677E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 2,000 8,785E-05 6,677E-03 ! positive regulation of ligase activity GO:0051351 86 70 2,000 9,579E-05 7,132E-03 ! pseudouridine synthase activity GO:0009982 12 12 1,000 1,032E-04 7,526E-03 ! midbody GO:0030496 14 12 1,000 1,032E-04 7,379E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 2,000 1,177E-04 8,255E-03 ! transcription initiation GO:0006352 84 75 2,000 1,177E-04 8,099E-03 ! nucleolar part GO:0044452 13 13 1,000 1,218E-04 8,229E-03 ! kinase regulator activity GO:0019207 93 76 2,000 1,224E-04 8,119E-03 ! cytosolic ribosome GO:0022626 82 76 2,000 1,224E-04 7,974E-03 ! regulation of ligase activity GO:0051340 95 78 2,000 1,322E-04 8,463E-03 ! positive regulation of protein modification process GO:0031401 100 78 2,000 1,322E-04 8,317E-03 ! pseudouridine synthesis GO:0001522 14 14 1,000 1,42E-04 8,78E-03 ! regulation of viral reproduction GO:0050792 16 14 1,000 1,42E-04 8,634E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 1,42E-04 8,492E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 2,000 1,59E-04 9,358E-03 GO:0010498|proteasomal protein catabolic process, ! negative regulation of cell cycle process GO:0010948 24 15 1,000 1,637E-04 9,48E-03 ! double-strand break repair via homologous recombination GO:0000724 36 15 1,000 1,637E-04 9,332E-03 GO:0000725|recombinational repair, ! centrosome cycle GO:0007098 26 16 1,000 1,87E-04 0,01049323 ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 1,000 1,87E-04 0,01033424 ! regulation of protein ubiquitination GO:0031396 27 16 1,000 1,87E-04 0,01018 ! protein kinase binding GO:0019901 115 89 2,000 1,956E-04 0,01049245 ! cell cycle arrest GO:0007050 103 93 2,000 2,227E-04 0,01177597 ! spindle microtubule GO:0005876 27 18 1,000 2,38E-04 0,01240379 ! nuclear ubiquitin ligase complex GO:0000152 31 18 1,000 2,38E-04 0,01222909 ! translational elongation GO:0006414 104 96 2,000 2,446E-04 0,01239448 ! cellular response to unfolded protein GO:0034620 21 19 1,000 2,658E-04 0,01328294 GO:0030968|endoplasmic reticulum unfolded protein response, ! chromosome condensation GO:0030261 20 19 1,000 2,658E-04 0,01310344 ! positive regulation of fibroblast proliferation GO:0048146 25 19 1,000 2,658E-04 0,01292872 ! response to light stimulus GO:0009416 131 100 2,000 2,759E-04 0,01324419 ! negative regulation of lipid metabolic process GO:0045833 34 20 1,000 2,951E-04 0,01398117 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 1,000 2,951E-04 0,01380193 ! apoptotic nuclear changes GO:0030262 24 21 1,000 3,259E-04 0,01504987 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 1,000 3,259E-04 0,01486175 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 1,000 3,259E-04 0,01467827 ! ubiquitin binding GO:0043130 25 21 1,000 3,259E-04 0,01449927 ! microtubule organizing center organization GO:0031023 33 22 1,000 3,582E-04 0,0157447 GO:0051297|centrosome organization, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 1,000 3,582E-04 0,01555727 ! DNA-directed RNA polymerase complex GO:0000428 23 22 1,000 3,582E-04 0,01537424 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! positive regulation of B cell activation GO:0050871 26 22 1,000 3,582E-04 0,01519547 ! androgen receptor binding GO:0050681 34 24 1,000 4,273E-04 0,01791886 ! intramolecular transferase activity GO:0016866 26 24 1,000 4,273E-04 0,01771524 ! RNA polymerase complex GO:0030880 25 24 1,000 4,273E-04 0,01751619 ! small conjugating protein binding GO:0032182 29 24 1,000 4,273E-04 0,01732157 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 1,000 4,273E-04 0,01713122 ! regulation of lipid biosynthetic process GO:0046890 35 25 1,000 4,641E-04 0,01840407 ! regulation of fibroblast proliferation GO:0048145 32 26 1,000 5,024E-04 0,01970793 ! response to endoplasmic reticulum stress GO:0034976 30 26 1,000 5,024E-04 0,01949827 ! fat cell differentiation GO:0045444 30 27 1,000 5,422E-04 0,02082016 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 5,422E-04 0,02060329 ! regulation of fatty acid metabolic process GO:0019217 41 28 1,000 5,834E-04 0,02194223 ! negative regulation of phosphorylation GO:0042326 30 28 1,000 5,834E-04 0,02171833 ! ER-nuclear signaling pathway GO:0006984 32 29 1,000 6,262E-04 0,0230734 ! regulation of microtubule-based process GO:0032886 41 30 1,000 6,704E-04 0,02445514 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 1,000 7,16E-04 0,02586263 GO:0045936|negative regulation of phosphate metabolic process, ! drug binding GO:0008144 34 31 1,000 7,16E-04 0,02560907 ! multicellular organismal metabolic process GO:0044236 35 32 1,000 7,632E-04 0,02702997 ! regulation of cellular ketone metabolic process GO:0010565 46 33 1,000 8,118E-04 0,02847488 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 1,000 8,118E-04 0,02820369 ! regulation of B cell activation GO:0050864 40 34 1,000 8,618E-04 0,0296605 ! steroid hormone receptor binding GO:0035258 44 34 1,000 8,618E-04 0,0293833 ! protein kinase inhibitor activity GO:0004860 37 34 1,000 8,618E-04 0,02911124 ! positive regulation of DNA metabolic process GO:0051054 53 35 1,000 9,134E-04 0,03056837 ! response to estrogen stimulus GO:0043627 48 35 1,000 9,134E-04 0,03029047 ! kinase inhibitor activity GO:0019210 47 35 1,000 9,134E-04 0,03001758 ! androgen receptor signaling pathway GO:0030521 47 35 1,000 9,134E-04 0,02974957 ! nucleus organization GO:0006997 42 36 1,000 9,663E-04 0,03119637 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 1,000 9,663E-04 0,03092272 ! cellular response to extracellular stimulus GO:0031668 37 36 1,000 9,663E-04 0,03065383 ! positive regulation of mast cell proliferation GO:0070668 43 36 1,000 9,663E-04 0,03038957 GO:0050671|positive regulation of lymphocyte proliferation, ! positive regulation of leukocyte proliferation GO:0070665 47 37 1,000 1,021E-03 0,03182663 GO:0032946|positive regulation of mononuclear cell proliferation, ! hydro-lyase activity GO:0016836 44 38 1,000 1,077E-03 0,03328402 ! DNA-dependent ATPase activity GO:0008094 63 39 1,000 1,134E-03 0,03476114 ! double-strand break repair GO:0006302 70 39 1,000 1,134E-03 0,03447146 ! RNA modification GO:0009451 39 39 1,000 1,134E-03 0,03418658 ! damaged DNA binding GO:0003684 51 40 1,000 1,193E-03 0,035663 ! protein serine/threonine phosphatase activity GO:0004722 45 42 1,000 1,314E-03 0,03898538 ! positive regulation of cell cycle GO:0045787 56 43 1,000 1,378E-03 0,04052567 ! carbon-oxygen lyase activity GO:0016835 53 47 1,000 1,644E-03 0,04797572 ! mRNA binding GO:0003729 65 47 1,000 1,644E-03 0,04759496 ! protein N-terminus binding GO:0047485 57 48 1,000 1,714E-03 0,04923474 ! regulation of gene expression, epigenetic GO:0040029 64 49 1,000 1,786E-03 0,05088902 ! negative regulation of cytoskeleton organization GO:0051494 73 49 1,000 1,786E-03 0,05049454 ! nucleotide-excision repair GO:0006289 53 49 1,000 1,786E-03 0,05010612 ! regulation of mast cell proliferation GO:0070666 57 49 1,000 1,786E-03 0,04972363 ! DNA damage response, signal transduction GO:0042770 84 50 1,000 1,859E-03 0,05136289 ! regulation of lymphocyte proliferation GO:0050670 61 52 1,000 2,009E-03 0,05509348 ! DNA catabolic process GO:0006308 57 53 1,000 2,086E-03 0,05678235 ! regulation of leukocyte proliferation GO:0070663 65 53 1,000 2,086E-03 0,05636174 GO:0032944|regulation of mononuclear cell proliferation, ! steroid hormone receptor signaling pathway GO:0030518 70 55 1,000 2,244E-03 0,06019739 ! response to steroid hormone stimulus GO:0048545 74 59 1,000 2,578E-03 0,06863762 ! regulation of cellular response to stress GO:0080135 79 59 1,000 2,578E-03 0,06814025 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 1,000 2,842E-03 0,07459191 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 1,000 2,842E-03 0,07405911 ! negative regulation of cell growth GO:0030308 69 63 1,000 2,933E-03 0,07588552 ! negative regulation of protein kinase activity GO:0006469 78 64 1,000 3,025E-03 0,07772106 ! tRNA processing GO:0008033 73 64 1,000 3,025E-03 0,07717756 ! response to unfolded protein GO:0006986 66 64 1,000 3,025E-03 0,0766416 ! nuclear hormone receptor binding GO:0035257 79 64 1,000 3,025E-03 0,07611304 ! negative regulation of cell size GO:0045792 71 65 1,000 3,119E-03 0,07793057 ! positive regulation of lymphocyte activation GO:0051251 83 65 1,000 3,119E-03 0,07740043 ! negative regulation of kinase activity GO:0033673 79 65 1,000 3,119E-03 0,07687745 ! tubulin binding GO:0015631 92 66 1,000 3,214E-03 0,07868632 ! negative regulation of organelle organization GO:0010639 93 68 1,000 3,408E-03 0,0828786 ! negative regulation of transferase activity GO:0051348 85 70 1,000 3,607E-03 0,08714489 ! hormone receptor binding GO:0051427 85 70 1,000 3,607E-03 0,08657157 ! positive regulation of phosphorylation GO:0042327 82 70 1,000 3,607E-03 0,08600574 ! response to protein stimulus GO:0051789 73 70 1,000 3,607E-03 0,08544726 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 1,000 3,812E-03 0,08971247 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of leukocyte activation GO:0002696 92 73 1,000 3,916E-03 0,09157678 ! phosphoinositide-mediated signaling GO:0048015 92 74 1,000 4,022E-03 0,09344812 ! ubiquitin ligase complex GO:0000151 91 74 1,000 4,022E-03 0,09285667 ! regulation of cell cycle process GO:0010564 113 75 1,000 4,129E-03 0,09472672 ! positive regulation of cell activation GO:0050867 94 75 1,000 4,129E-03 0,09413468 ! negative regulation of growth GO:0045926 85 76 1,000 4,237E-03 0,09600341 ! regulation of lipid metabolic process GO:0019216 98 76 1,000 4,237E-03 0,0954108 ! condensed chromosome GO:0000793 106 76 1,000 4,237E-03 0,09482545 ! regulation of DNA metabolic process GO:0051052 139 84 1,000 5,15E-03 0,11456192 ! DNA recombination GO:0006310 147 84 1,000 5,15E-03 0,1138676 ! microtubule cytoskeleton organization GO:0000226 113 87 1,000 5,514E-03 0,12117697 ! protein tyrosine phosphatase activity GO:0004725 109 89 1,000 5,763E-03 0,12588943 ! spindle GO:0005819 126 92 1,000 6,146E-03 0,13345568 ! regulation of cytoskeleton organization GO:0051493 133 93 1,000 6,276E-03 0,13547607 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 6,395E-03 0,13721893 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 6,395E-03 0,13641648 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 6,395E-03 0,13562336 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 6,395E-03 0,13483941 ! response to superoxide GO:0000303 5 5 0,000 6,395E-03 0,13406447 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 6,395E-03 0,13329839 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 6,395E-03 0,13254101 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 6,395E-03 0,13179219 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 6,395E-03 0,13105178 ! quinolinate metabolic process GO:0046874 5 5 0,000 6,395E-03 0,13031965 ! biotin binding GO:0009374 7 5 0,000 6,395E-03 0,12959565 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 6,395E-03 0,12887966 ! tongue development GO:0043586 6 5 0,000 6,395E-03 0,12817153 ! nose development GO:0043584 5 5 0,000 6,395E-03 0,12747113 ! cell proliferation in forebrain GO:0021846 5 5 0,000 6,395E-03 0,12677836 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 6,395E-03 0,12609307 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 6,395E-03 0,12541515 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 6,395E-03 0,12474448 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 6,395E-03 0,12408094 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 6,395E-03 0,12342443 ! glycolipid transport GO:0046836 6 5 0,000 6,395E-03 0,12277483 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 6,395E-03 0,12213203 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 6,395E-03 0,12149593 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 6,395E-03 0,12086641 ! neuron adhesion GO:0007158 5 5 0,000 6,395E-03 0,12024339 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 6,395E-03 0,11962676 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 6,395E-03 0,11901642 ! opioid peptide activity GO:0001515 6 5 0,000 6,395E-03 0,11841227 ! selenocysteine incorporation GO:0001514 5 5 0,000 6,395E-03 0,11781423 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 6,395E-03 0,1172222 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 6,395E-03 0,11663609 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 6,395E-03 0,11605581 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 6,395E-03 0,11548128 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 6,395E-03 0,1149124 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,395E-03 0,11434911 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 6,395E-03 0,11379131 ! clathrin coat assembly GO:0048268 6 5 0,000 6,395E-03 0,11323892 ! cerebral cortex cell migration GO:0021795 5 5 0,000 6,395E-03 0,11269187 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 6,395E-03 0,11215008 ! membrane hyperpolarization GO:0060081 5 5 0,000 6,395E-03 0,11161348 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 6,395E-03 0,11108199 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 6,395E-03 0,11055553 ! translation repressor activity GO:0030371 8 5 0,000 6,395E-03 0,11003405 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 6,395E-03 0,10951745 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 6,395E-03 0,10900569 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 6,395E-03 0,10849869 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 6,395E-03 0,10799638 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 6,395E-03 0,1074987 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 6,395E-03 0,10700559 ! negative regulation of heart contraction GO:0045822 5 5 0,000 6,395E-03 0,10651698 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 6,395E-03 0,10603281 ! microfibril GO:0001527 5 5 0,000 6,395E-03 0,10555302 ! troponin I binding GO:0031013 5 5 0,000 6,395E-03 0,10507756 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 6,395E-03 0,10460636 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 6,395E-03 0,10413936 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 6,395E-03 0,10367652 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 6,395E-03 0,10321778 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 6,395E-03 0,10276307 ! protein lipoylation GO:0009249 14 5 0,000 6,395E-03 0,10231236 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,395E-03 0,10186558 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 6,395E-03 0,10142269 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 6,395E-03 0,10098363 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 6,395E-03 0,10054835 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 6,395E-03 0,10011681 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 6,395E-03 0,09968896 ! glutamate catabolic process GO:0006538 6 5 0,000 6,395E-03 0,09926476 ! microvillus organization GO:0032528 5 5 0,000 6,395E-03 0,09884414 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 6,395E-03 0,09842708 ! tyrosine catabolic process GO:0006572 5 5 0,000 6,395E-03 0,09801352 ! response to pH GO:0009268 5 5 0,000 6,395E-03 0,09760342 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 6,395E-03 0,09719674 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 6,395E-03 0,09679343 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 6,395E-03 0,09639346 ! polyol biosynthetic process GO:0046173 5 5 0,000 6,395E-03 0,09599678 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 6,395E-03 0,09560335 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,395E-03 0,09521313 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 6,395E-03 0,09482609 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 6,395E-03 0,09444218 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 6,395E-03 0,09406136 ! anaerobic glycolysis GO:0019642 5 5 0,000 6,395E-03 0,0936836 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 6,395E-03 0,09330887 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 6,395E-03 0,09293712 ! peroxisomal matrix GO:0005782 5 5 0,000 6,395E-03 0,09256832 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 6,395E-03 0,09220244 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 6,395E-03 0,09183944 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 6,395E-03 0,09147928 ! multivesicular body GO:0005771 5 5 0,000 6,395E-03 0,09112194 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 6,395E-03 0,09076738 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 6,395E-03 0,09041557 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 6,395E-03 0,09006648 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 6,395E-03 0,08972007 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 6,395E-03 0,08937631 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 6,395E-03 0,08903518 ! epithelial cell maturation GO:0002070 14 5 0,000 6,395E-03 0,08869664 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 6,395E-03 0,08836067 ! muscle thin filament assembly GO:0030240 5 5 0,000 6,395E-03 0,08802724 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 6,395E-03 0,08769631 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 6,395E-03 0,08736786 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 6,395E-03 0,08704186 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,395E-03 0,08671828 ! positive regulation of translational initiation GO:0045948 6 5 0,000 6,395E-03 0,0863971 ! nonhomologous end joining complex GO:0070419 6 5 0,000 6,395E-03 0,08607829 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 6,395E-03 0,08576183 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 6,395E-03 0,08544768 ! ATPase activator activity GO:0001671 5 5 0,000 6,395E-03 0,08513583 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 6,395E-03 0,08482625 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 6,395E-03 0,0845189 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 6,395E-03 0,08421378 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 6,395E-03 0,08391085 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 6,395E-03 0,0836101 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 6,395E-03 0,08331149 ! cardiac myofibril assembly GO:0055003 5 5 0,000 6,395E-03 0,08301501 ! anterograde axon cargo transport GO:0008089 6 5 0,000 6,395E-03 0,08272063 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,395E-03 0,08242833 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 6,395E-03 0,08213809 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 6,395E-03 0,08184989 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 6,395E-03 0,0815637 ! protein localization to telomere GO:0070198 7 5 0,000 6,395E-03 0,0812795 ! response to exogenous dsRNA GO:0043330 5 5 0,000 6,395E-03 0,08099728 ! MutSalpha complex binding GO:0032407 7 5 0,000 6,395E-03 0,08071702 ! bile acid biosynthetic process GO:0006699 5 5 0,000 6,395E-03 0,08043868 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 6,395E-03 0,08016226 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 6,395E-03 0,07988773 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,395E-03 0,07961508 ! nerve growth factor binding GO:0048406 7 5 0,000 6,395E-03 0,07934428 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 6,395E-03 0,07907531 ! high-density lipoprotein binding GO:0008035 6 5 0,000 6,395E-03 0,07880817 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 6,395E-03 0,07854282 ! transcription initiation factor activity GO:0016986 5 5 0,000 6,395E-03 0,07827925 ! gas homeostasis GO:0033483 5 5 0,000 6,395E-03 0,07801745 ! Schwann cell development GO:0014044 5 5 0,000 6,395E-03 0,07775739 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 6,395E-03 0,07749906 ! cyclohydrolase activity GO:0019238 5 5 0,000 6,395E-03 0,07724244 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 6,395E-03 0,07698752 ! response to pheromone GO:0019236 5 5 0,000 6,395E-03 0,07673427 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 6,395E-03 0,07648268 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 6,395E-03 0,07623274 ! rhombomere development GO:0021546 6 5 0,000 6,395E-03 0,07598442 ! alanine transport GO:0032328 6 5 0,000 6,395E-03 0,07573772 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 6,395E-03 0,07549261 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 6,395E-03 0,07524909 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 6,395E-03 0,07500713 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 6,395E-03 0,07476672 ! regulation of meiosis GO:0040020 6 5 0,000 6,395E-03 0,07452785 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 6,395E-03 0,0742905 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 6,395E-03 0,07405466 ! lymphocyte costimulation GO:0031294 5 5 0,000 6,395E-03 0,07382031 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 6,395E-03 0,07358744 ! RS domain binding GO:0050733 6 5 0,000 6,395E-03 0,07335603 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 6,395E-03 0,07312607 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 6,395E-03 0,07289756 ! B cell homeostasis GO:0001782 6 5 0,000 6,395E-03 0,07267046 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 6,395E-03 0,07244478 ! anaphase GO:0051322 7 5 0,000 6,395E-03 0,07222049 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 6,395E-03 0,07199759 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 6,395E-03 0,07177605 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 6,395E-03 0,07155588 ! AP-2 adaptor complex GO:0030122 5 5 0,000 6,395E-03 0,07133706 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 6,395E-03 0,07111957 ! diuresis GO:0030146 5 5 0,000 6,395E-03 0,0709034 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 6,395E-03 0,07068854 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 6,395E-03 0,07047498 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 6,395E-03 0,0702627 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 6,395E-03 0,0700517 ! GTP-Rho binding GO:0017049 5 5 0,000 6,395E-03 0,06984197 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 6,395E-03 0,06963349 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,395E-03 0,06942624 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 6,395E-03 0,06922023 ! brown fat cell differentiation GO:0050873 5 5 0,000 6,395E-03 0,06901544 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,395E-03 0,06881185 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 6,395E-03 0,06860946 ! TAP complex GO:0042825 5 5 0,000 6,395E-03 0,06840826 ! platelet dense granule GO:0042827 6 5 0,000 6,395E-03 0,06820824 ! bHLH transcription factor binding GO:0043425 5 5 0,000 6,395E-03 0,06800938 ! secretory granule organization GO:0033363 5 5 0,000 6,395E-03 0,06781168 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 6,395E-03 0,06761512 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 6,395E-03 0,0674197 ! lamin binding GO:0005521 8 5 0,000 6,395E-03 0,06722541 ! aldehyde-lyase activity GO:0016832 6 5 0,000 6,395E-03 0,06703223 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,395E-03 0,06684017 ! neural plate morphogenesis GO:0001839 6 5 0,000 6,395E-03 0,06664919 ! cyclosporin A binding GO:0016018 6 5 0,000 6,395E-03 0,06645931 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 6,395E-03 0,0662705 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 6,395E-03 0,06608277 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 6,395E-03 0,06589609 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 6,395E-03 0,06571047 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 6,395E-03 0,06552589 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 6,395E-03 0,06534235 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 6,395E-03 0,06515983 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 6,395E-03 0,06497832 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 6,395E-03 0,06479783 ! organ or tissue specific immune response GO:0002251 6 5 0,000 6,395E-03 0,06461833 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 6,395E-03 0,06443983 ! retina homeostasis GO:0001895 5 5 0,000 6,395E-03 0,06426231 ! prepulse inhibition GO:0060134 8 5 0,000 6,395E-03 0,06408576 ! maternal placenta development GO:0001893 5 5 0,000 6,395E-03 0,06391019 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 6,395E-03 0,06373557 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 6,395E-03 0,0635619 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 6,395E-03 0,06338918 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 6,395E-03 0,06321739 ! protein palmitoylation GO:0018345 5 5 0,000 6,395E-03 0,06304653 ! protein amino acid prenylation GO:0018346 6 5 0,000 6,395E-03 0,0628766 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 6,395E-03 0,06270757 ! stem cell division GO:0017145 6 5 0,000 6,395E-03 0,06253946 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 6,395E-03 0,06237224 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 6,395E-03 0,06220591 ! organ regeneration GO:0031100 6 5 0,000 6,395E-03 0,06204047 ! lymphocyte apoptosis GO:0070227 6 5 0,000 6,395E-03 0,06187591 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 6,395E-03 0,06171222 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 6,395E-03 0,06154939 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 6,395E-03 0,06138741 ! acyl carrier activity GO:0000036 5 5 0,000 6,395E-03 0,06122629 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 6,395E-03 0,06106601 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 6,395E-03 0,06090657 ! phagocytic vesicle GO:0045335 5 5 0,000 6,395E-03 0,06074796 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 6,395E-03 0,06059018 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 6,395E-03 0,06043321 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 6,395E-03 0,06027705 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 6,395E-03 0,06012169 ! polyol transport GO:0015791 8 5 0,000 6,395E-03 0,05996714 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 6,395E-03 0,05981338 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 6,395E-03 0,0596604 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 6,395E-03 0,05950821 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 6,395E-03 0,05935679 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 6,395E-03 0,05920614 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 6,395E-03 0,05905625 ! ethanol metabolic process GO:0006067 6 5 0,000 6,395E-03 0,05890712 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 6,395E-03 0,05875873 ! cobalt ion transport GO:0006824 5 5 0,000 6,395E-03 0,0586111 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 6,395E-03 0,0584642 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 6,395E-03 0,05831804 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 6,395E-03 0,05817261 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 6,395E-03 0,0580279 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 6,395E-03 0,05788391 ! sterol carrier activity GO:0005498 6 5 0,000 6,395E-03 0,05774064 ! adaptation of signaling pathway GO:0022401 6 5 0,000 6,395E-03 0,05759807 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 6,395E-03 0,0574562 ! response to acid GO:0001101 7 5 0,000 6,395E-03 0,05731503 ! fibril organization GO:0043206 5 5 0,000 6,395E-03 0,05717455 ! malate metabolic process GO:0006108 6 5 0,000 6,395E-03 0,05703476 ! regulation of dopamine uptake GO:0051584 7 5 0,000 6,395E-03 0,05689565 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 6,395E-03 0,05675722 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 6,395E-03 0,05661946 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 6,395E-03 0,05648237 ! protein maturation by protein folding GO:0022417 5 5 0,000 6,395E-03 0,05634594 ! activation of protein kinase B activity GO:0032148 15 5 0,000 6,395E-03 0,05621016 ! origin recognition complex GO:0000808 5 5 0,000 6,395E-03 0,05607504 ! neurexin binding GO:0042043 6 5 0,000 6,395E-03 0,05594057 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 6,395E-03 0,05580674 ! protein amino acid dealkylation GO:0008214 5 5 0,000 6,395E-03 0,05567355 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 6,395E-03 0,05554099 ! lipoic acid binding GO:0031405 5 5 0,000 6,395E-03 0,05540907 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 6,395E-03 0,05527777 ! lithium ion binding GO:0031403 6 5 0,000 6,395E-03 0,05514709 ! grooming behavior GO:0007625 7 5 0,000 6,395E-03 0,05501702 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 6,395E-03 0,05488757 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 6,395E-03 0,05475873 ! lymph vessel development GO:0001945 6 5 0,000 6,395E-03 0,05463049 ! bicarbonate transport GO:0015701 5 5 0,000 6,395E-03 0,05450284 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 0,000 6,395E-03 0,0543758 GO:0010811|positive regulation of cell-substrate adhesion, ! response to interferon-gamma GO:0034341 6 5 0,000 6,395E-03 0,05424934 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 6,395E-03 0,05412347 ! endothelial cell proliferation GO:0001935 8 5 0,000 6,395E-03 0,05399819 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 6,395E-03 0,05387348 ! dorsal spinal cord development GO:0021516 6 5 0,000 6,395E-03 0,05374935 ! activation of MAPKKK activity GO:0000185 5 5 0,000 6,395E-03 0,05362579 ! synaptic vesicle maturation GO:0016188 6 5 0,000 6,395E-03 0,05350279 ! sphingoid catabolic process GO:0046521 5 5 0,000 6,395E-03 0,05338036 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 6,395E-03 0,05325849 ! neutrophil mediated immunity GO:0002446 5 5 0,000 6,395E-03 0,05313717 ! intercellular canaliculus GO:0046581 5 5 0,000 6,395E-03 0,0530164 ! dopamine binding GO:0035240 7 5 0,000 6,395E-03 0,05289619 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 6,395E-03 0,05277651 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 6,395E-03 0,05265738 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 6,395E-03 0,05253878 ! amine oxidase activity GO:0008131 7 5 0,000 6,395E-03 0,05242071 ! monocyte activation GO:0042117 9 5 0,000 6,395E-03 0,05230318 ! negative regulation of protein binding GO:0032091 5 5 0,000 6,395E-03 0,05218617 ! regulation of response to food GO:0032095 5 5 0,000 6,395E-03 0,05206968 ! response to food GO:0032094 6 5 0,000 6,395E-03 0,05195371 ! positive regulation of protein binding GO:0032092 5 5 0,000 6,395E-03 0,05183826 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 6,395E-03 0,05172332 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 6,395E-03 0,05160889 ! hedgehog receptor activity GO:0008158 5 5 0,000 6,395E-03 0,05149496 ! lipoprotein catabolic process GO:0042159 5 5 0,000 6,395E-03 0,05138154 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 6,395E-03 0,05126861 ! purine salvage GO:0043101 7 5 0,000 6,395E-03 0,05115618 ! small-subunit processome GO:0032040 5 5 0,000 6,395E-03 0,05104424 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 6,395E-03 0,05093279 ! ciliary rootlet GO:0035253 5 5 0,000 6,395E-03 0,05082182 ! myosin heavy chain binding GO:0032036 5 5 0,000 6,395E-03 0,05071134 ! nucleobase transport GO:0015851 5 5 0,000 6,395E-03 0,05060134 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 6,395E-03 0,05049181 ! GPI anchor binding GO:0034235 6 5 0,000 6,395E-03 0,05038276 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,395E-03 0,05027418 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 6,395E-03 0,05016606 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 6,395E-03 0,05005841 ! basic amino acid transport GO:0015802 5 5 0,000 6,395E-03 0,04995122 ! dendritic shaft GO:0043198 5 5 0,000 6,395E-03 0,04984448 ! terminal button GO:0043195 7 5 0,000 6,395E-03 0,0497382 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 6,395E-03 0,04963238 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 6,395E-03 0,049527 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 6,395E-03 0,04942207 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 6,395E-03 0,04931758 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 6,395E-03 0,04921354 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 6,395E-03 0,04910993 ! response to UV-C GO:0010225 15 5 0,000 6,395E-03 0,04900676 ! positive regulation of organ growth GO:0046622 5 5 0,000 6,395E-03 0,04890402 ! response to arsenic GO:0046685 6 5 0,000 6,395E-03 0,04880171 ! IgE binding GO:0019863 5 5 0,000 6,395E-03 0,04869983 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 6,395E-03 0,04859837 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 6,395E-03 0,04849733 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 6,395E-03 0,04839672 ! response to copper ion GO:0046688 5 5 0,000 6,395E-03 0,04829652 ! response to cadmium ion GO:0046686 5 5 0,000 6,395E-03 0,04819673 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 6,395E-03 0,04809736 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 6,395E-03 0,04799839 ! protein autoprocessing GO:0016540 6 5 0,000 6,395E-03 0,04789983 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 6,395E-03 0,04780168 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 6,395E-03 0,04770392 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 6,395E-03 0,04760657 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 6,395E-03 0,04750961 ! mitotic recombination GO:0006312 15 5 0,000 6,395E-03 0,04741304 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 6,395E-03 0,04731687 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 6,395E-03 0,04722109 ! membrane to membrane docking GO:0022614 5 5 0,000 6,395E-03 0,04712569 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 6,395E-03 0,04703068 ! translation activator activity GO:0008494 5 5 0,000 6,395E-03 0,04693605 ! somatostatin receptor activity GO:0004994 5 5 0,000 6,395E-03 0,0468418 ! melanocortin receptor activity GO:0004977 6 5 0,000 6,395E-03 0,04674793 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 6,395E-03 0,04665444 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 6,395E-03 0,04656131 ! salivary gland morphogenesis GO:0007435 5 5 0,000 6,395E-03 0,04646856 ! galactosidase activity GO:0015925 5 5 0,000 6,395E-03 0,04637618 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 6,395E-03 0,04628416 ! cellular response to nutrient GO:0031670 5 5 0,000 6,395E-03 0,04619251 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 6,395E-03 0,04610122 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 6,395E-03 0,04601029 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 6,395E-03 0,04591972 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 6,395E-03 0,0458295 ! A band GO:0031672 5 5 0,000 6,395E-03 0,04573964 ! heat generation GO:0031649 5 5 0,000 6,395E-03 0,04565013 ! flagellum organization GO:0043064 5 5 0,000 6,395E-03 0,04556097 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 6,395E-03 0,04547216 ! disaccharide metabolic process GO:0005984 6 5 0,000 6,395E-03 0,04538369 ! glycogen catabolic process GO:0005980 16 5 0,000 6,395E-03 0,04529557 ! dopamine biosynthetic process GO:0042416 6 5 0,000 6,395E-03 0,04520779 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 6,395E-03 0,04512034 ! chromocenter GO:0010369 5 5 0,000 6,395E-03 0,04503324 ! glial cell migration GO:0008347 5 5 0,000 6,395E-03 0,04494647 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 6,395E-03 0,04486003 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 6,395E-03 0,04477393 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 6,395E-03 0,04468816 ! growth hormone receptor binding GO:0005131 5 5 0,000 6,395E-03 0,04460271 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 6,395E-03 0,04451759 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 6,395E-03 0,0444328 ! aminomethyltransferase activity GO:0004047 5 5 0,000 6,395E-03 0,04434832 ! aminoacylase activity GO:0004046 5 5 0,000 6,395E-03 0,04426417 ! penetration of zona pellucida GO:0007341 6 5 0,000 6,395E-03 0,04418034 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 6,395E-03 0,04409682 ! nucleus localization GO:0051647 5 5 0,000 6,395E-03 0,04401362 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 6,395E-03 0,04393073 ! carnitine metabolic process GO:0009437 5 5 0,000 6,395E-03 0,04384815 GO:0006577|betaine metabolic process, ! DNA packaging GO:0006323 113 94 1,000 6,408E-03 0,04385544 ! perinuclear region of cytoplasm GO:0048471 125 97 1,000 6,809E-03 0,04651853 ! negative regulation of cellular component organization GO:0051129 132 99 1,000 7,084E-03 0,04830085 ! regulation of lymphocyte activation GO:0051249 123 100 1,000 7,223E-03 0,0491563 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,669E-03 0,05209586 ! regulation of helicase activity GO:0051095 6 6 0,000 7,669E-03 0,05199903 ! response to oxygen radical GO:0000305 6 6 0,000 7,669E-03 0,05190255 ! positive regulation of axon extension GO:0045773 7 6 0,000 7,669E-03 0,05180644 ! forebrain neuron differentiation GO:0021879 6 6 0,000 7,669E-03 0,05171068 ! forebrain regionalization GO:0021871 7 6 0,000 7,669E-03 0,05161527 ! meiotic prophase I GO:0007128 7 6 0,000 7,669E-03 0,05152021 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 7,669E-03 0,05142551 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 7,669E-03 0,05133115 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 7,669E-03 0,05123713 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 7,669E-03 0,05114347 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 7,669E-03 0,05105014 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 7,669E-03 0,05095715 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 7,669E-03 0,0508645 ! protein amino acid sulfation GO:0006477 9 6 0,000 7,669E-03 0,05077219 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 7,669E-03 0,05068021 ! establishment of tissue polarity GO:0007164 8 6 0,000 7,669E-03 0,05058856 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 7,669E-03 0,05049725 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 7,669E-03 0,05040626 ! embryonic camera-type eye development GO:0031076 9 6 0,000 7,669E-03 0,0503156 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 7,669E-03 0,05022527 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 7,669E-03 0,05013526 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 7,669E-03 0,05004557 ! Notch receptor processing GO:0007220 7 6 0,000 7,669E-03 0,04995621 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 7,669E-03 0,04986716 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 7,669E-03 0,04977843 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 7,669E-03 0,04969001 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 7,669E-03 0,04960191 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 7,669E-03 0,04951412 ! neurofilament GO:0005883 7 6 0,000 7,669E-03 0,04942664 ! glial cell fate commitment GO:0021781 7 6 0,000 7,669E-03 0,04933946 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 7,669E-03 0,0492526 ! dynactin complex GO:0005869 7 6 0,000 7,669E-03 0,04916604 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 7,669E-03 0,04907978 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 7,669E-03 0,04899383 ! oocyte maturation GO:0001556 6 6 0,000 7,669E-03 0,04890817 ! DNA replication origin binding GO:0003688 6 6 0,000 7,669E-03 0,04882282 ! reflex GO:0060004 10 6 0,000 7,669E-03 0,04873776 ! positive regulation of glycolysis GO:0045821 6 6 0,000 7,669E-03 0,048653 ! parathyroid gland development GO:0060017 6 6 0,000 7,669E-03 0,04856853 ! anagen GO:0042640 7 6 0,000 7,669E-03 0,04848436 ! protein-cofactor linkage GO:0018065 15 6 0,000 7,669E-03 0,04840048 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 7,669E-03 0,04831688 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 7,669E-03 0,04823358 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 7,669E-03 0,04815056 ! skeletal myofibril assembly GO:0014866 6 6 0,000 7,669E-03 0,04806783 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 7,669E-03 0,04798538 ! cysteine metabolic process GO:0006534 7 6 0,000 7,669E-03 0,04790321 ! glycine catabolic process GO:0006546 6 6 0,000 7,669E-03 0,04782133 ! adenohypophysis development GO:0021984 6 6 0,000 7,669E-03 0,04773972 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 7,669E-03 0,04765839 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 7,669E-03 0,04757734 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 7,669E-03 0,04749656 ! microtubule nucleation GO:0007020 7 6 0,000 7,669E-03 0,04741606 ! proline biosynthetic process GO:0006561 8 6 0,000 7,669E-03 0,04733583 ! tryptophan metabolic process GO:0006568 6 6 0,000 7,669E-03 0,04725587 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 7,669E-03 0,04717618 ! thyroid hormone generation GO:0006590 6 6 0,000 7,669E-03 0,04709676 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 7,669E-03 0,04701761 ! retinoid X receptor binding GO:0046965 7 6 0,000 7,669E-03 0,04693872 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 7,669E-03 0,04686009 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 7,669E-03 0,04678173 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 7,669E-03 0,04670363 ! sister chromatid cohesion GO:0007062 6 6 0,000 7,669E-03 0,04662579 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 7,669E-03 0,04654821 ! positive regulation of transporter activity GO:0032411 8 6 0,000 7,669E-03 0,04647089 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 7,669E-03 0,04639382 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 7,669E-03 0,04631701 ! p53 binding GO:0002039 6 6 0,000 7,669E-03 0,04624046 ! demethylase activity GO:0032451 6 6 0,000 7,669E-03 0,04616415 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 7,669E-03 0,0460881 ! regulation of platelet activation GO:0010543 7 6 0,000 7,669E-03 0,0460123 ! lipid phosphatase activity GO:0042577 7 6 0,000 7,669E-03 0,04593674 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 7,669E-03 0,04586144 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 7,669E-03 0,04578638 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 7,669E-03 0,04571156 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 7,669E-03 0,04563699 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 7,669E-03 0,04556266 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 7,669E-03 0,04548858 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 7,669E-03 0,04541473 ! LIM domain binding GO:0030274 7 6 0,000 7,669E-03 0,04534113 ! negative regulation of translational initiation GO:0045947 6 6 0,000 7,669E-03 0,04526776 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 7,669E-03 0,04519463 ! 5S class rRNA transcription GO:0042791 6 6 0,000 7,669E-03 0,04512173 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 7,669E-03 0,04504907 ! axon guidance receptor activity GO:0008046 6 6 0,000 7,669E-03 0,04497665 ! zinc ion homeostasis GO:0055069 7 6 0,000 7,669E-03 0,04490446 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 7,669E-03 0,04483249 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 7,669E-03 0,04476076 ! protein targeting to lysosome GO:0006622 6 6 0,000 7,669E-03 0,04468926 ! hyaluronan metabolic process GO:0030212 8 6 0,000 7,669E-03 0,04461798 ! protein retention in ER lumen GO:0006621 6 6 0,000 7,669E-03 0,04454694 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 7,669E-03 0,04447611 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 7,669E-03 0,04440552 ! dynein binding GO:0045502 6 6 0,000 7,669E-03 0,04433514 ! regulation of dendrite development GO:0050773 6 6 0,000 7,669E-03 0,04426499 ! peptidyl-arginine modification GO:0018195 6 6 0,000 7,669E-03 0,04419506 ! eating behavior GO:0042755 7 6 0,000 7,669E-03 0,04412536 ! protein localization to chromosome GO:0034502 8 6 0,000 7,669E-03 0,04405587 ! Hsp90 protein binding GO:0051879 7 6 0,000 7,669E-03 0,0439866 ! glycolipid binding GO:0051861 7 6 0,000 7,669E-03 0,04391754 ! MutLalpha complex binding GO:0032405 8 6 0,000 7,669E-03 0,04384871 ! mast cell activation GO:0045576 6 6 0,000 7,669E-03 0,04378009 ! regulation of focal adhesion formation GO:0051893 6 6 0,000 7,669E-03 0,04371168 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,669E-03 0,04364349 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 7,669E-03 0,04357551 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 7,669E-03 0,04350774 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 7,669E-03 0,04344018 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 7,669E-03 0,04337283 ! lipoxygenase activity GO:0016165 6 6 0,000 7,669E-03 0,04330569 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 7,669E-03 0,04323876 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 7,669E-03 0,04317203 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 7,669E-03 0,04310551 ! DNA replication factor C complex GO:0005663 7 6 0,000 7,669E-03 0,04303919 ! DNA replication factor A complex GO:0005662 7 6 0,000 7,669E-03 0,04297308 ! establishment of chromosome localization GO:0051303 15 6 0,000 7,669E-03 0,04290717 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 7,669E-03 0,04284146 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 7,669E-03 0,04277596 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 7,669E-03 0,04271065 ! chromatin assembly complex GO:0005678 16 6 0,000 7,669E-03 0,04264554 ! sex chromatin GO:0001739 6 6 0,000 7,669E-03 0,04258063 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 7,669E-03 0,04251592 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 7,669E-03 0,0424514 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 7,669E-03 0,04238708 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 7,669E-03 0,04232296 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 7,669E-03 0,04225903 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 7,669E-03 0,04219529 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 7,669E-03 0,04213174 ! phosphatidylserine binding GO:0001786 6 6 0,000 7,669E-03 0,04206838 ! alpha-mannosidase activity GO:0004559 8 6 0,000 7,669E-03 0,04200522 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 7,669E-03 0,04194224 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 7,669E-03 0,04187945 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 7,669E-03 0,04181685 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 7,669E-03 0,04175444 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 7,669E-03 0,04169221 ! leading edge membrane GO:0031256 8 6 0,000 7,669E-03 0,04163017 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 7,669E-03 0,04156831 ! CARD domain binding GO:0050700 6 6 0,000 7,669E-03 0,04150664 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 7,669E-03 0,04144515 ! COPII vesicle coat GO:0030127 7 6 0,000 7,669E-03 0,04138384 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 7,669E-03 0,04132271 ! glutathione biosynthetic process GO:0006750 7 6 0,000 7,669E-03 0,04126176 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 7,669E-03 0,04120099 ! positive regulation of epidermis development GO:0045684 8 6 0,000 7,669E-03 0,04114041 ! proteasome regulator activity GO:0010860 6 6 0,000 7,669E-03 0,04107999 ! ceramidase activity GO:0017040 6 6 0,000 7,669E-03 0,04101976 ! antibiotic transport GO:0042891 7 6 0,000 7,669E-03 0,0409597 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 7,669E-03 0,04089982 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 7,669E-03 0,04084011 ! sodium channel regulator activity GO:0017080 6 6 0,000 7,669E-03 0,04078058 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,669E-03 0,04072122 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 7,669E-03 0,04066203 ! response to fluid shear stress GO:0034405 6 6 0,000 7,669E-03 0,04060301 ! lymph node development GO:0048535 6 6 0,000 7,669E-03 0,04054417 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 7,669E-03 0,04048549 ! triglyceride catabolic process GO:0019433 15 6 0,000 7,669E-03 0,04042699 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 7,669E-03 0,04036865 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 7,669E-03 0,04031048 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 7,669E-03 0,04025248 ! negative regulation of lipase activity GO:0060192 6 6 0,000 7,669E-03 0,04019465 ! activation of innate immune response GO:0002218 6 6 0,000 7,669E-03 0,04013698 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 7,669E-03 0,04007948 ! sarcoglycan complex GO:0016012 8 6 0,000 7,669E-03 0,04002214 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 7,669E-03 0,03996497 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 7,669E-03 0,03990795 ! neural plate development GO:0001840 7 6 0,000 7,669E-03 0,0398511 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 7,669E-03 0,03979442 ! catecholamine transport GO:0051937 6 6 0,000 7,669E-03 0,03973789 ! ether hydrolase activity GO:0016803 7 6 0,000 7,669E-03 0,03968153 ! FACIT collagen GO:0005593 6 6 0,000 7,669E-03 0,03962532 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 7,669E-03 0,03956927 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 7,669E-03 0,03951338 ! collagen type IV GO:0005587 6 6 0,000 7,669E-03 0,03945765 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 7,669E-03 0,03940208 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 7,669E-03 0,03934666 ! drug metabolic process GO:0017144 6 6 0,000 7,669E-03 0,0392914 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 7,669E-03 0,03923629 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 7,669E-03 0,03918134 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 7,669E-03 0,03912654 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 7,669E-03 0,03907189 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 7,669E-03 0,0390174 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 7,669E-03 0,03896306 ! cellular anion homeostasis GO:0030002 6 6 0,000 7,669E-03 0,03890887 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 7,669E-03 0,03885483 ! negative regulation of protein ubiquitination GO:0031397 7 6 0,000 7,669E-03 0,03880094 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 7,669E-03 0,0387472 ! behavioral response to cocaine GO:0048148 9 6 0,000 7,669E-03 0,0386936 ! translation initiation factor binding GO:0031369 6 6 0,000 7,669E-03 0,03864016 ! nucleotide-sugar transport GO:0015780 6 6 0,000 7,669E-03 0,03858686 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 7,669E-03 0,03853371 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 7,669E-03 0,03848071 ! quaternary ammonium group binding GO:0050997 7 6 0,000 7,669E-03 0,03842785 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 7,669E-03 0,03837514 ! reproductive behavior GO:0019098 8 6 0,000 7,669E-03 0,03832257 ! response to growth hormone stimulus GO:0060416 7 6 0,000 7,669E-03 0,03827014 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 7,669E-03 0,03821786 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 7,669E-03 0,03816572 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 7,669E-03 0,03811373 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 7,669E-03 0,03806187 ! induction of positive chemotaxis GO:0050930 7 6 0,000 7,669E-03 0,03801016 ! cohesin complex GO:0008278 6 6 0,000 7,669E-03 0,03795858 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 7,669E-03 0,03790715 ! citrate metabolic process GO:0006101 7 6 0,000 7,669E-03 0,03785585 ! myelin sheath GO:0043209 8 6 0,000 7,669E-03 0,0378047 ! phototransduction, visible light GO:0007603 6 6 0,000 7,669E-03 0,03775368 ! opsonization GO:0008228 7 6 0,000 7,669E-03 0,0377028 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 7,669E-03 0,03765205 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 7,669E-03 0,03760145 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 7,669E-03 0,03755097 ! regulation of potassium ion transport GO:0043266 8 6 0,000 7,669E-03 0,03750064 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 7,669E-03 0,03745044 ! chemoattractant activity GO:0042056 6 6 0,000 7,669E-03 0,03740037 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 7,669E-03 0,03735043 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 7,669E-03 0,03730063 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 7,669E-03 0,03725097 ! leukocyte degranulation GO:0043299 6 6 0,000 7,669E-03 0,03720143 ! bile acid and bile salt transport GO:0015721 7 6 0,000 7,669E-03 0,03715203 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 7,669E-03 0,03710275 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 7,669E-03 0,03705361 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 7,669E-03 0,0370046 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 7,669E-03 0,03695571 ! ceramide biosynthetic process GO:0046513 6 6 0,000 7,669E-03 0,03690696 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 7,669E-03 0,03685833 ! activin receptor activity GO:0017002 7 6 0,000 7,669E-03 0,03680984 ! astrocyte differentiation GO:0048708 6 6 0,000 7,669E-03 0,03676147 ! syncytium formation GO:0006949 6 6 0,000 7,669E-03 0,03671322 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 7,669E-03 0,03666511 ! neutrophil activation GO:0042119 6 6 0,000 7,669E-03 0,03661711 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 7,669E-03 0,03656925 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 7,669E-03 0,03652151 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 7,669E-03 0,03647389 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 7,669E-03 0,0364264 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 7,669E-03 0,03637903 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 7,669E-03 0,03633179 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 7,669E-03 0,03628466 ! neuron apoptosis GO:0051402 7 6 0,000 7,669E-03 0,03623766 ! folic acid transport GO:0015884 8 6 0,000 7,669E-03 0,03619078 ! carnitine transport GO:0015879 6 6 0,000 7,669E-03 0,03614403 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 7,669E-03 0,03609739 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 7,669E-03 0,03605087 ! S-methyltransferase activity GO:0008172 6 6 0,000 7,669E-03 0,03600447 ! phospholipase D activity GO:0004630 6 6 0,000 7,669E-03 0,03595819 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 7,669E-03 0,03591204 ! intercalated disc GO:0014704 8 6 0,000 7,669E-03 0,03586599 ! G2/M transition checkpoint GO:0031576 24 6 0,000 7,669E-03 0,03582007 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 7,669E-03 0,03577427 ! IgG binding GO:0019864 6 6 0,000 7,669E-03 0,03572858 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 7,669E-03 0,035683 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 7,669E-03 0,03563755 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 7,669E-03 0,03559221 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 7,669E-03 0,03554698 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 7,669E-03 0,03550187 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 7,669E-03 0,03545688 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 7,669E-03 0,03541199 ! dendrite morphogenesis GO:0048813 7 6 0,000 7,669E-03 0,03536723 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 7,669E-03 0,03532257 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 7,669E-03 0,03527803 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 7,669E-03 0,0352336 ! nucleosome disassembly GO:0006337 7 6 0,000 7,669E-03 0,03518928 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 7,669E-03 0,03514507 ! regulation of mast cell activation GO:0033003 6 6 0,000 7,669E-03 0,03510097 ! tetracycline transporter activity GO:0008493 7 6 0,000 7,669E-03 0,03505699 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 7,669E-03 0,03501311 ! receptor internalization GO:0031623 8 6 0,000 7,669E-03 0,03496934 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 7,669E-03 0,03492569 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 7,669E-03 0,03488214 ! histamine receptor activity GO:0004969 7 6 0,000 7,669E-03 0,0348387 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 7,669E-03 0,03479537 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 7,669E-03 0,03475214 ! protein deubiquitination GO:0016579 6 6 0,000 7,669E-03 0,03470903 ! axonal fasciculation GO:0007413 7 6 0,000 7,669E-03 0,03466602 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 7,669E-03 0,03462311 ! cytidine deaminase activity GO:0004126 6 6 0,000 7,669E-03 0,03458032 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 7,669E-03 0,03453762 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 7,669E-03 0,03449504 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 7,669E-03 0,03445256 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 7,669E-03 0,03441018 ! glycine binding GO:0016594 9 6 0,000 7,669E-03 0,03436791 ! apical protein localization GO:0045176 7 6 0,000 7,669E-03 0,03432574 ! ankyrin binding GO:0030506 6 6 0,000 7,669E-03 0,03428367 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 7,669E-03 0,03424171 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 7,669E-03 0,03419985 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 7,669E-03 0,03415809 ! progesterone metabolic process GO:0042448 6 6 0,000 7,669E-03 0,03411643 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 7,669E-03 0,03407488 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 7,669E-03 0,03403343 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 7,669E-03 0,03399207 ! ATP catabolic process GO:0006200 6 6 0,000 7,669E-03 0,03395082 ! CoA carboxylase activity GO:0016421 6 6 0,000 7,669E-03 0,03390967 ! determination of adult lifespan GO:0008340 6 6 0,000 7,669E-03 0,03386861 ! S-acyltransferase activity GO:0016417 6 6 0,000 7,669E-03 0,03382766 ! somatic stem cell maintenance GO:0035019 6 6 0,000 7,669E-03 0,03378681 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 7,669E-03 0,03374605 ! IkappaB kinase complex GO:0008385 7 6 0,000 7,669E-03 0,03370539 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 7,669E-03 0,03366483 ! store-operated calcium channel activity GO:0015279 6 6 0,000 7,669E-03 0,03362437 ! alkaline phosphatase activity GO:0004035 7 6 0,000 7,669E-03 0,033584 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 7,669E-03 0,03354374 ! unconventional myosin complex GO:0016461 8 6 0,000 7,669E-03 0,03350356 ! tRNA transcription GO:0009304 7 7 0,000 8,941E-03 0,03901677 ! respiratory burst GO:0045730 7 7 0,000 8,941E-03 0,03897016 ! telencephalon cell migration GO:0022029 8 7 0,000 8,941E-03 0,03892365 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 8,941E-03 0,03887726 ! cation:chloride symporter activity GO:0015377 8 7 0,000 8,941E-03 0,03883098 ! RNA cap binding GO:0000339 8 7 0,000 8,941E-03 0,0387848 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 8,941E-03 0,03873874 ! ephrin receptor binding GO:0046875 9 7 0,000 8,941E-03 0,03869279 ! male meiosis I GO:0007141 7 7 0,000 8,941E-03 0,03864694 ! synapsis GO:0007129 7 7 0,000 8,941E-03 0,03860121 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 8,941E-03 0,03855558 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 8,941E-03 0,03851006 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 8,941E-03 0,03846465 ! signal peptide processing GO:0006465 7 7 0,000 8,941E-03 0,03841934 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 8,941E-03 0,03837414 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 8,941E-03 0,03832905 ! macrophage chemotaxis GO:0048246 7 7 0,000 8,941E-03 0,03828406 ! Golgi cisterna membrane GO:0032580 7 7 0,000 8,941E-03 0,03823918 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 8,941E-03 0,0381944 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 8,941E-03 0,03814973 ! smoothened signaling pathway GO:0007224 8 7 0,000 8,941E-03 0,03810516 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 8,941E-03 0,0380607 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 8,941E-03 0,03801634 ! cytoplasmic microtubule GO:0005881 7 7 0,000 8,941E-03 0,03797208 ! Arp2/3 protein complex GO:0005885 8 7 0,000 8,941E-03 0,03792793 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 8,941E-03 0,03788388 ! ATPase binding GO:0051117 8 7 0,000 8,941E-03 0,03783993 ! positive regulation of isotype switching GO:0045830 7 7 0,000 8,941E-03 0,03779608 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 8,941E-03 0,03775234 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 8,941E-03 0,03770869 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 8,941E-03 0,03766515 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,941E-03 0,03762171 ! thymic T cell selection GO:0045061 16 7 0,000 8,941E-03 0,03757836 ! transepithelial chloride transport GO:0030321 7 7 0,000 8,941E-03 0,03753512 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 8,941E-03 0,03749198 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 8,941E-03 0,03744893 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 8,941E-03 0,03740599 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 8,941E-03 0,03736314 ! melanocyte differentiation GO:0030318 8 7 0,000 8,941E-03 0,03732039 ! malate dehydrogenase activity GO:0016615 8 7 0,000 8,941E-03 0,03727774 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 8,941E-03 0,03723518 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 8,941E-03 0,03719273 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 8,941E-03 0,03715037 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 8,941E-03 0,0371081 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 8,941E-03 0,03706593 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 8,941E-03 0,03702386 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 8,941E-03 0,03698188 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 8,941E-03 0,03694 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 8,941E-03 0,03689821 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 8,941E-03 0,03685652 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 8,941E-03 0,03681492 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 8,941E-03 0,03677342 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 8,941E-03 0,03673201 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 8,941E-03 0,03669069 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 8,941E-03 0,03664946 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 8,941E-03 0,03660833 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 8,941E-03 0,03656729 ! melanosome organization GO:0032438 7 7 0,000 8,941E-03 0,03652634 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 8,941E-03 0,03648548 ! mesodermal cell differentiation GO:0048333 9 7 0,000 8,941E-03 0,03644472 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 8,941E-03 0,03640404 ! Rac protein signal transduction GO:0016601 7 7 0,000 8,941E-03 0,03636346 ! chondrocyte differentiation GO:0002062 7 7 0,000 8,941E-03 0,03632296 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 8,941E-03 0,03628256 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 8,941E-03 0,03624225 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 8,941E-03 0,03620202 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 8,941E-03 0,03616189 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 8,941E-03 0,03612184 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 8,941E-03 0,03608188 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 8,941E-03 0,03604201 ! Schwann cell differentiation GO:0014037 8 7 0,000 8,941E-03 0,03600223 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 8,941E-03 0,03596254 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 8,941E-03 0,03592293 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 8,941E-03 0,03588341 ! vinculin binding GO:0017166 9 7 0,000 8,941E-03 0,03584398 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 8,941E-03 0,03580463 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 8,941E-03 0,03576537 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 8,941E-03 0,0357262 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 8,941E-03 0,03568711 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 8,941E-03 0,03564811 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 8,941E-03 0,03560919 ! cardiac muscle cell development GO:0055013 8 7 0,000 8,941E-03 0,03557036 ! fibrinolysis GO:0042730 9 7 0,000 8,941E-03 0,03553161 ! response to tropane GO:0014073 10 7 0,000 8,941E-03 0,03549295 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 8,941E-03 0,03545437 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 8,941E-03 0,03541587 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 8,941E-03 0,03537746 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 8,941E-03 0,03533913 ! laminin-1 complex GO:0005606 7 7 0,000 8,941E-03 0,03530089 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 8,941E-03 0,03526272 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 8,941E-03 0,03522464 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 8,941E-03 0,03518665 ! regulation of cell division GO:0051302 7 7 0,000 8,941E-03 0,03514873 ! holo TFIIH complex GO:0005675 7 7 0,000 8,941E-03 0,03511089 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 8,941E-03 0,03507314 ! chitinase activity GO:0004568 7 7 0,000 8,941E-03 0,03503547 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 8,941E-03 0,03499788 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 8,941E-03 0,03496037 ! regulation of respiratory burst GO:0060263 8 7 0,000 8,941E-03 0,03492293 ! prophase GO:0051324 8 7 0,000 8,941E-03 0,03488558 ! peptidyl-histidine modification GO:0018202 8 7 0,000 8,941E-03 0,03484831 ! centriolar satellite GO:0034451 10 7 0,000 8,941E-03 0,03481112 ! BBSome GO:0034464 7 7 0,000 8,941E-03 0,03477401 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 8,941E-03 0,03473698 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 8,941E-03 0,03470002 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 8,941E-03 0,03466315 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 8,941E-03 0,03462635 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 8,941E-03 0,03458963 ! regulation of synaptogenesis GO:0051963 7 7 0,000 8,941E-03 0,03455299 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 8,941E-03 0,03451642 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 8,941E-03 0,03447994 ! glycolipid catabolic process GO:0019377 7 7 0,000 8,941E-03 0,03444353 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 8,941E-03 0,03440719 ! circadian behavior GO:0048512 9 7 0,000 8,941E-03 0,03437094 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 8,941E-03 0,03433476 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 8,941E-03 0,03429865 ! striatum development GO:0021756 7 7 0,000 8,941E-03 0,03426263 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 8,941E-03 0,03422667 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 8,941E-03 0,0341908 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 8,941E-03 0,034155 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 8,941E-03 0,03411927 ! dystroglycan complex GO:0016011 9 7 0,000 8,941E-03 0,03408362 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 8,941E-03 0,03404804 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 8,941E-03 0,03401253 ! peroxiredoxin activity GO:0051920 7 7 0,000 8,941E-03 0,0339771 ! muscle adaptation GO:0043500 7 7 0,000 8,941E-03 0,03394175 ! regulation of muscle adaptation GO:0043502 7 7 0,000 8,941E-03 0,03390647 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 8,941E-03 0,03387126 ! lysogeny GO:0030069 7 7 0,000 8,941E-03 0,03383612 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 8,941E-03 0,03380106 ! sequestering of metal ion GO:0051238 9 7 0,000 8,941E-03 0,03376607 ! membrane attack complex GO:0005579 7 7 0,000 8,941E-03 0,03373115 ! fibrinogen complex GO:0005577 7 7 0,000 8,941E-03 0,0336963 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 8,941E-03 0,03366153 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 8,941E-03 0,03362683 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 8,941E-03 0,03359219 ! GABA receptor binding GO:0050811 8 7 0,000 8,941E-03 0,03355763 ! sheet-forming collagen GO:0030935 7 7 0,000 8,941E-03 0,03352315 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 8,941E-03 0,03348873 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 8,941E-03 0,03345438 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 8,941E-03 0,0334201 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 8,941E-03 0,0333859 ! 7S RNA binding GO:0008312 8 7 0,000 8,941E-03 0,03335176 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 8,941E-03 0,03331769 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 8,941E-03 0,03328369 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 8,941E-03 0,03324977 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 8,941E-03 0,03321591 ! Golgi to endosome transport GO:0006895 8 7 0,000 8,941E-03 0,03318212 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 8,941E-03 0,03314839 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 8,941E-03 0,03311474 ! fibril GO:0043205 7 7 0,000 8,941E-03 0,03308116 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 8,941E-03 0,03304764 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 8,941E-03 0,03301419 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 8,941E-03 0,03298081 ! sensory perception of bitter taste GO:0050913 7 7 0,000 8,941E-03 0,0329475 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 8,941E-03 0,03291425 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 8,941E-03 0,03288107 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 8,941E-03 0,03284796 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 8,941E-03 0,03281491 ! equilibrioception GO:0050957 10 7 0,000 8,941E-03 0,03278193 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 8,941E-03 0,03274902 ! titin binding GO:0031432 7 7 0,000 8,941E-03 0,03271617 ! chemosensory behavior GO:0007635 9 7 0,000 8,941E-03 0,03268339 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 8,941E-03 0,03265067 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 8,941E-03 0,03261802 ! cobalamin binding GO:0031419 7 7 0,000 8,941E-03 0,03258544 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 8,941E-03 0,03255291 ! response to axon injury GO:0048678 9 7 0,000 8,941E-03 0,03252046 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 8,941E-03 0,03248807 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 8,941E-03 0,03245574 ! F-actin capping protein complex GO:0008290 8 7 0,000 8,941E-03 0,03242348 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 8,941E-03 0,03239128 ! cGMP-mediated signaling GO:0019934 8 7 0,000 8,941E-03 0,03235915 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 8,941E-03 0,03232708 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 8,941E-03 0,03229507 ! senescence GO:0010149 8 7 0,000 8,941E-03 0,03226313 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 8,941E-03 0,03223125 ! nuclear localization sequence binding GO:0008139 8 7 0,000 8,941E-03 0,03219943 ! galactose metabolic process GO:0006012 8 7 0,000 8,941E-03 0,03216767 ! vesicle fusion GO:0006906 8 7 0,000 8,941E-03 0,03213598 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 8,941E-03 0,03210435 ! intracellular pH reduction GO:0051452 7 7 0,000 8,941E-03 0,03207278 ! glycerol ether catabolic process GO:0044269 16 7 0,000 8,941E-03 0,03204128 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 8,941E-03 0,03200983 ! ruffle organization GO:0031529 9 7 0,000 8,941E-03 0,03197845 ! nucleoside transport GO:0015858 8 7 0,000 8,941E-03 0,03194713 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 8,941E-03 0,03191587 ! inclusion body GO:0016234 7 7 0,000 8,941E-03 0,03188467 ! Cajal body GO:0015030 7 7 0,000 8,941E-03 0,03185354 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 8,941E-03 0,03182246 ! rRNA modification GO:0000154 7 7 0,000 8,941E-03 0,03179144 ! PcG protein complex GO:0031519 7 7 0,000 8,941E-03 0,03176049 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 8,941E-03 0,03172959 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 8,941E-03 0,03169876 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 8,941E-03 0,03166798 ! apolipoprotein binding GO:0034185 9 7 0,000 8,941E-03 0,03163727 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 8,941E-03 0,03160661 ! segment specification GO:0007379 9 7 0,000 8,941E-03 0,03157601 ! pronucleus GO:0045120 25 7 0,000 8,941E-03 0,03154547 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 8,941E-03 0,031515 ! Rac GTPase activator activity GO:0030675 9 7 0,000 8,941E-03 0,03148458 ! preribosome GO:0030684 7 7 0,000 8,941E-03 0,03145421 ! hair follicle maturation GO:0048820 8 7 0,000 8,941E-03 0,03142391 ! renal water homeostasis GO:0003091 7 7 0,000 8,941E-03 0,03139367 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 8,941E-03 0,03136348 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 8,941E-03 0,03133335 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 8,941E-03 0,03130328 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 8,941E-03 0,03127327 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 8,941E-03 0,03124331 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 8,941E-03 0,03121342 ! phosphofructokinase activity GO:0008443 7 7 0,000 8,941E-03 0,03118358 ! gap junction channel activity GO:0005243 8 7 0,000 8,941E-03 0,03115379 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 8,941E-03 0,03112407 ! histone methylation GO:0016571 7 7 0,000 8,941E-03 0,0310944 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 8,941E-03 0,03106478 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 8,941E-03 0,03103522 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 8,941E-03 0,03100572 ! muscle cell proliferation GO:0033002 8 7 0,000 8,941E-03 0,03097628 ! transcription termination GO:0006353 9 7 0,000 8,941E-03 0,03094689 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 8,941E-03 0,03091756 ! cytidylyltransferase activity GO:0070567 8 7 0,000 8,941E-03 0,03088828 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 8,941E-03 0,03085905 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 8,941E-03 0,03082989 ! salivary gland development GO:0007431 7 7 0,000 8,941E-03 0,03080077 ! glucosidase activity GO:0015926 8 7 0,000 8,941E-03 0,03077172 ! NuRD complex GO:0016581 8 7 0,000 8,941E-03 0,03074271 ! negative regulation of nuclear division GO:0051784 7 7 0,000 8,941E-03 0,03071377 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 8,941E-03 0,03068487 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 8,941E-03 0,03065603 ! response to redox state GO:0051775 8 7 0,000 8,941E-03 0,03062725 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 8,941E-03 0,03059852 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 8,941E-03 0,03056984 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 8,941E-03 0,03054122 ! actin monomer binding GO:0003785 7 7 0,000 8,941E-03 0,03051265 ! protein prenyltransferase activity GO:0008318 8 7 0,000 8,941E-03 0,03048413 ! endosome to lysosome transport GO:0008333 7 7 0,000 8,941E-03 0,03045567 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 8,941E-03 0,03042726 ! germ cell migration GO:0008354 7 7 0,000 8,941E-03 0,0303989 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 8,941E-03 0,0303706 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 8,941E-03 0,03034234 ! CoA-ligase activity GO:0016405 8 7 0,000 8,941E-03 0,03031415 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 8,941E-03 0,030286 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 8,941E-03 0,0302579 ! embryonic heart tube development GO:0035050 8 7 0,000 8,941E-03 0,03022986 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 8,941E-03 0,03020187 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 8,941E-03 0,03017393 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 8,941E-03 0,03014604 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 8,941E-03 0,03011821 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 8,941E-03 0,03009042 ! adenylate kinase activity GO:0004017 8 7 0,000 8,941E-03 0,03006269 ! negative regulation of immune effector process GO:0002698 13 7 0,000 8,941E-03 0,03003501 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 8,941E-03 0,03000738 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 8,941E-03 0,0299798 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 0,01021241 0,03421016 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 0,01021241 0,03417877 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 0,01021241 0,03414744 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 0,01021241 0,03411617 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 0,01021241 0,03408496 ! proteasome regulatory particle GO:0005838 8 8 0,000 0,01021241 0,0340538 ! SMAD protein complex assembly GO:0007183 10 8 0,000 0,01021241 0,0340227 ! regulation of smooth muscle cell migration GO:0014910 11 8 0,000 0,01021241 0,03399166 ! protein self-association GO:0043621 8 8 0,000 0,01021241 0,03396067 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 0,01021241 0,03392974 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 0,01021241 0,03389887 ! neurotransmitter uptake GO:0001504 8 8 0,000 0,01021241 0,03386805 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 0,01021241 0,03383729 ! guanylate cyclase activity GO:0004383 9 8 0,000 0,01021241 0,03380659 ! troponin complex GO:0005861 8 8 0,000 0,01021241 0,03377594 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 0,01021241 0,03374534 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 0,01021241 0,03371481 ! keratinocyte proliferation GO:0043616 9 8 0,000 0,01021241 0,03368432 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 0,01021241 0,03365389 ! microtubule bundle formation GO:0001578 8 8 0,000 0,01021241 0,03362352 ! middle ear morphogenesis GO:0042474 10 8 0,000 0,01021241 0,0335932 ! ganglioside metabolic process GO:0001573 8 8 0,000 0,01021241 0,03356294 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 0,01021241 0,03353273 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 0,01021241 0,03350257 ! ciliary or flagellar motility GO:0001539 8 8 0,000 0,01021241 0,03347247 ! pathogenesis GO:0009405 8 8 0,000 0,01021241 0,03344242 ! pH reduction GO:0045851 9 8 0,000 0,01021241 0,03341243 ! small protein activating enzyme activity GO:0008641 10 8 0,000 0,01021241 0,03338249 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 0,01021241 0,0333526 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 0,01021241 0,03332277 ! hemoglobin metabolic process GO:0020027 8 8 0,000 0,01021241 0,03329299 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 0,01021241 0,03326327 ! arginine catabolic process GO:0006527 9 8 0,000 0,01021241 0,03323359 ! T-tubule GO:0030315 9 8 0,000 0,01021241 0,03320397 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 0,01021241 0,03317441 ! histidine catabolic process GO:0006548 8 8 0,000 0,01021241 0,03314489 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 0,01021241 0,03311543 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 0,01021241 0,03308602 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 0,01021241 0,03305666 ! proline metabolic process GO:0006560 10 8 0,000 0,01021241 0,03302736 ! L-serine metabolic process GO:0006563 9 8 0,000 0,01021241 0,0329981 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 0,01021241 0,0329689 ! melanosome membrane GO:0033162 9 8 0,000 0,01021241 0,03293975 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01021241 0,03291065 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 0,01021241 0,03288161 ! pericentriolar material GO:0000242 9 8 0,000 0,01021241 0,03285261 ! reverse cholesterol transport GO:0043691 8 8 0,000 0,01021241 0,03282366 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 0,01021241 0,03279477 ! melanin metabolic process GO:0006582 10 8 0,000 0,01021241 0,03276593 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 0,01021241 0,03273713 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 0,01021241 0,03270839 ! Golgi lumen GO:0005796 8 8 0,000 0,01021241 0,0326797 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 0,01021241 0,03265106 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 0,01021241 0,03262247 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 0,01021241 0,03259393 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 0,01021241 0,03256544 ! stereocilium bundle GO:0032421 11 8 0,000 0,01021241 0,032537 ! forebrain cell migration GO:0021885 9 8 0,000 0,01021241 0,0325086 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 0,01021241 0,03248026 ! osteoblast development GO:0002076 11 8 0,000 0,01021241 0,03245197 ! retinoic acid metabolic process GO:0042573 8 8 0,000 0,01021241 0,03242372 ! retinol metabolic process GO:0042572 8 8 0,000 0,01021241 0,03239553 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 0,01021241 0,03236738 ! structural constituent of epidermis GO:0030280 9 8 0,000 0,01021241 0,03233929 ! clathrin binding GO:0030276 10 8 0,000 0,01021241 0,03231124 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 0,01021241 0,03228324 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 0,01021241 0,03225529 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 0,01021241 0,03222739 ! motor axon guidance GO:0008045 8 8 0,000 0,01021241 0,03219953 ! protein targeting to vacuole GO:0006623 8 8 0,000 0,01021241 0,03217173 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 0,01021241 0,03214397 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 0,01021241 0,03211626 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 0,01021241 0,0320886 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 0,01021241 0,03206098 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01021241 0,03203341 ! protein-lipid complex assembly GO:0065005 8 8 0,000 0,01021241 0,03200589 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 0,01021241 0,03197842 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 0,01021241 0,03195099 ! regulation of dopamine secretion GO:0014059 9 8 0,000 0,01021241 0,03192362 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 0,01021241 0,03189628 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 0,01021241 0,031869 ! subpallium development GO:0021544 8 8 0,000 0,01021241 0,03184176 ! positive regulation of Rho GTPase activity GO:0032321 11 8 0,000 0,01021241 0,03181457 ! icosanoid secretion GO:0032309 10 8 0,000 0,01021241 0,03178742 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 0,01021241 0,03176032 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 0,01021241 0,03173327 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 0,01021241 0,03170626 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 0,01021241 0,0316793 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 0,01021241 0,03165239 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 0,01021241 0,03162552 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 0,01021241 0,03159869 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 0,01021241 0,03157191 ! ubiquinone metabolic process GO:0006743 9 8 0,000 0,01021241 0,03154518 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 0,01021241 0,03151849 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 0,01021241 0,03149185 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 0,01021241 0,03146525 ! Wnt receptor activity GO:0042813 11 8 0,000 0,01021241 0,0314387 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 0,01021241 0,03141219 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 0,01021241 0,03138573 ! detection of calcium ion GO:0005513 9 8 0,000 0,01021241 0,03135931 ! negative regulation of glucose import GO:0046325 9 8 0,000 0,01021241 0,03133293 ! blastocyst growth GO:0001832 8 8 0,000 0,01021241 0,0313066 ! regulation of fibrinolysis GO:0051917 8 8 0,000 0,01021241 0,03128032 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 0,01021241 0,03125408 ! cerebellar cortex formation GO:0021697 9 8 0,000 0,01021241 0,03122788 ! complement binding GO:0001848 11 8 0,000 0,01021241 0,03120172 ! regulation of actin filament bundle formation GO:0032231 13 8 0,000 0,01021241 0,03117561 GO:0051492|regulation of stress fiber formation, ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 0,01021241 0,03114955 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 0,01021241 0,03112353 ! amino sugar catabolic process GO:0046348 8 8 0,000 0,01021241 0,03109755 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 0,01021241 0,03107161 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 0,01021241 0,03104572 ! positive regulation of amine transport GO:0051954 9 8 0,000 0,01021241 0,03101987 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 0,01021241 0,03099406 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 0,01021241 0,0309683 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01021241 0,03094257 ! Golgi transport complex GO:0017119 8 8 0,000 0,01021241 0,0309169 ! GDP binding GO:0019003 9 8 0,000 0,01021241 0,03089126 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 0,01021241 0,03086567 ! prostate gland development GO:0030850 17 8 0,000 0,01021241 0,03084012 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 0,01021241 0,03081461 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 0,01021241 0,03078914 ! phosphate transport GO:0006817 9 8 0,000 0,01021241 0,03076372 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 0,01021241 0,03073833 ! oligopeptide transport GO:0006857 8 8 0,000 0,01021241 0,03071299 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 0,01021241 0,03068769 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 0,01021241 0,03066244 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 0,01021241 0,03063722 ! lipoprotein transport GO:0042953 9 8 0,000 0,01021241 0,03061205 ! estrogen metabolic process GO:0008210 8 8 0,000 0,01021241 0,03058691 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 0,01021241 0,03056182 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 0,01021241 0,03053677 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 0,01021241 0,03051176 ! T-helper 1 type immune response GO:0042088 8 8 0,000 0,01021241 0,03048679 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 0,01021241 0,03046186 ! response to amphetamine GO:0001975 11 8 0,000 0,01021241 0,03043698 ! mechanosensory behavior GO:0007638 8 8 0,000 0,01021241 0,03041213 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 0,01021241 0,03038732 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 0,01021241 0,03036256 ! C-X-C chemokine binding GO:0019958 8 8 0,000 0,01021241 0,03033783 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 0,01021241 0,03031315 ! glycerolipid catabolic process GO:0046503 17 8 0,000 0,01021241 0,0302885 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 0,01021241 0,0302639 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 0,01021241 0,03023933 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 0,01021241 0,03021481 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 0,01021241 0,03019032 ! pigment granule organization GO:0048753 9 8 0,000 0,01021241 0,03016588 ! GTP-dependent protein binding GO:0030742 11 8 0,000 0,01021241 0,03014147 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 0,01021241 0,03011711 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 0,01021241 0,03009278 ! regulation of pigmentation during development GO:0048070 11 8 0,000 0,01021241 0,03006849 ! macrophage activation GO:0042116 8 8 0,000 0,01021241 0,03004424 ! poly(A) RNA binding GO:0008143 8 8 0,000 0,01021241 0,03002003 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 0,01021241 0,02999586 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 0,01021241 0,02997173 ! asymmetric protein localization GO:0008105 9 8 0,000 0,01021241 0,02994764 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 0,01021241 0,02992358 ! neurotrophin binding GO:0043121 10 8 0,000 0,01021241 0,02989957 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 0,01021241 0,02987559 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 0,01021241 0,02985165 ! phagocytosis, engulfment GO:0006911 10 8 0,000 0,01021241 0,02982775 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 0,01021241 0,02980389 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 0,01021241 0,02978006 ! UV protection GO:0009650 9 8 0,000 0,01021241 0,02975628 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 0,01021241 0,02973253 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 0,01021241 0,02970882 ! glutathione peroxidase activity GO:0004602 17 8 0,000 0,01021241 0,02968515 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 0,01021241 0,02966151 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 0,01021241 0,02963792 ! ferric iron binding GO:0008199 9 8 0,000 0,01021241 0,02961436 ! response to UV-B GO:0010224 10 8 0,000 0,01021241 0,02959083 ! intermediate filament organization GO:0045109 8 8 0,000 0,01021241 0,02956735 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 0,01021241 0,0295439 ! cellular extravasation GO:0045123 9 8 0,000 0,01021241 0,02952049 ! skeletal muscle contraction GO:0003009 8 8 0,000 0,01021241 0,02949712 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 0,01021241 0,02947378 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01021241 0,02945048 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 0,01021241 0,02942722 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 0,01021241 0,02940399 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 0,01021241 0,0293808 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 0,01021241 0,02935765 ! erythrocyte development GO:0048821 9 8 0,000 0,01021241 0,02933454 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 0,01021241 0,02931146 ! ribosome assembly GO:0042255 8 8 0,000 0,01021241 0,02928841 ! gamma-tubulin binding GO:0043015 8 8 0,000 0,01021241 0,0292654 ! NADPH oxidase complex GO:0043020 8 8 0,000 0,01021241 0,02924243 ! mRNA cleavage GO:0006379 9 8 0,000 0,01021241 0,0292195 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 0,01021241 0,0291966 ! opioid receptor activity GO:0004985 8 8 0,000 0,01021241 0,02917373 ! zymogen activation GO:0031638 9 8 0,000 0,01021241 0,02915091 ! coenzyme A metabolic process GO:0015936 8 8 0,000 0,01021241 0,02912812 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 0,01021241 0,02910536 ! costamere GO:0043034 8 8 0,000 0,01021241 0,02908264 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 0,01021241 0,02905995 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 0,01021241 0,0290373 ! sarcomere organization GO:0045214 9 8 0,000 0,01021241 0,02901469 ! wide pore channel activity GO:0022829 9 8 0,000 0,01021241 0,02899211 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 0,01021241 0,02896956 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 0,01021241 0,02894705 ! hormone catabolic process GO:0042447 9 8 0,000 0,01021241 0,02892458 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 0,01021241 0,02890214 ! cGMP biosynthetic process GO:0006182 9 8 0,000 0,01021241 0,02887974 ! lysozyme activity GO:0003796 10 8 0,000 0,01021241 0,02885737 ! death receptor binding GO:0005123 8 8 0,000 0,01021241 0,02883503 ! protein modification by small protein removal GO:0070646 9 8 0,000 0,01021241 0,02881273 ! adult feeding behavior GO:0008343 9 8 0,000 0,01021241 0,02879046 ! microtubule basal body GO:0005932 8 8 0,000 0,01021241 0,02876823 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 0,01021241 0,02874603 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 0,01021241 0,02872387 ! calcium-release channel activity GO:0015278 8 8 0,000 0,01021241 0,02870174 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 0,01021241 0,02867965 ! behavioral response to nicotine GO:0035095 9 8 0,000 0,01021241 0,02865758 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 0,01021241 0,02863556 ! adenosine deaminase activity GO:0004000 8 8 0,000 0,01021241 0,02861356 ! NAD biosynthetic process GO:0009435 9 8 0,000 0,01021241 0,0285916 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 0,01148191 0,03212116 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 0,01148191 0,03209655 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 0,01148191 0,03207197 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 0,01148191 0,03204744 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 0,01148191 0,03202294 ! myotube differentiation GO:0014902 9 9 0,000 0,01148191 0,03199847 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 0,01148191 0,03197405 ! N-glycan processing GO:0006491 10 9 0,000 0,01148191 0,03194966 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 0,01148191 0,0319253 ! actin-myosin filament sliding GO:0033275 11 9 0,000 0,01148191 0,03190099 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 0,01148191 0,03187671 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 0,01148191 0,03185247 ! RNA methylation GO:0001510 9 9 0,000 0,01148191 0,03182827 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 0,01148191 0,0318041 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 0,01148191 0,03177997 ! artery development GO:0060840 9 9 0,000 0,01148191 0,03175588 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 0,01148191 0,03173182 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 0,01148191 0,0317078 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 0,01148191 0,03168381 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 0,01148191 0,03165986 ! positive regulation of heart contraction GO:0045823 11 9 0,000 0,01148191 0,03163595 ! lipopolysaccharide binding GO:0001530 9 9 0,000 0,01148191 0,03161207 ! regulated secretory pathway GO:0045055 10 9 0,000 0,01148191 0,03158823 ! estrogen receptor binding GO:0030331 9 9 0,000 0,01148191 0,03156443 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 0,01148191 0,03154066 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 0,01148191 0,03151693 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 0,01148191 0,03149323 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 0,01148191 0,03146957 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 0,000 0,01148191 0,03144595 ! urea metabolic process GO:0019627 19 9 0,000 0,01148191 0,03142235 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 0,01148191 0,0313988 ! autophagic vacuole GO:0005776 11 9 0,000 0,01148191 0,03137528 ! Rac GTPase binding GO:0048365 10 9 0,000 0,01148191 0,0313518 ! response to dietary excess GO:0002021 9 9 0,000 0,01148191 0,03132835 ! regulation of sodium ion transport GO:0002028 10 9 0,000 0,01148191 0,03130493 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01148191 0,03128155 ! lens development in camera-type eye GO:0002088 9 9 0,000 0,01148191 0,03125821 ! male sex determination GO:0030238 9 9 0,000 0,01148191 0,0312349 ! positive regulation of vasodilation GO:0045909 19 9 0,000 0,01148191 0,03121162 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 0,01148191 0,03118838 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 0,01148191 0,03116518 ! male germ cell nucleus GO:0001673 11 9 0,000 0,01148191 0,03114201 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 0,01148191 0,03111887 ! copper ion homeostasis GO:0055070 9 9 0,000 0,01148191 0,03109577 ! protein heterooligomerization GO:0051291 10 9 0,000 0,01148191 0,0310727 ! spectrin GO:0008091 9 9 0,000 0,01148191 0,03104967 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 0,01148191 0,03102667 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 0,01148191 0,0310037 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 0,01148191 0,03098077 ! regulation of B cell differentiation GO:0045577 10 9 0,000 0,01148191 0,03095787 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 0,01148191 0,03093501 ! neural tube patterning GO:0021532 10 9 0,000 0,01148191 0,03091218 ! fucose catabolic process GO:0019317 10 9 0,000 0,01148191 0,03088938 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 0,01148191 0,03086662 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 0,01148191 0,03084389 ! sterol catabolic process GO:0016127 10 9 0,000 0,01148191 0,03082119 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 0,01148191 0,03079853 ! clathrin coat of coated pit GO:0030132 11 9 0,000 0,01148191 0,0307759 ! SNARE complex GO:0031201 11 9 0,000 0,01148191 0,0307533 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 0,01148191 0,03073074 ! negative regulation of glucose transport GO:0010829 10 9 0,000 0,01148191 0,03070821 ! methionine biosynthetic process GO:0009086 11 9 0,000 0,01148191 0,03068571 ! peptidoglycan binding GO:0042834 9 9 0,000 0,01148191 0,03066325 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 0,01148191 0,03064082 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 0,01148191 0,03061842 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 0,01148191 0,03059605 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 0,01148191 0,03057372 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 0,01148191 0,03055142 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 0,01148191 0,03052915 ! detection of bacterium GO:0016045 10 9 0,000 0,01148191 0,03050692 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 0,01148191 0,03048472 ! embryonic gut development GO:0048566 10 9 0,000 0,01148191 0,03046254 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 0,01148191 0,03044041 ! desmosome GO:0030057 10 9 0,000 0,01148191 0,0304183 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 0,01148191 0,03039623 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 0,01148191 0,03037418 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 0,01148191 0,03035217 ! actin filament polymerization GO:0030041 10 9 0,000 0,01148191 0,03033019 ! negative regulation of B cell activation GO:0050869 10 9 0,000 0,01148191 0,03030825 ! establishment of cell polarity GO:0030010 10 9 0,000 0,01148191 0,03028633 ! regulation of synapse organization GO:0050807 10 9 0,000 0,01148191 0,03026445 ! septin complex GO:0031105 10 9 0,000 0,01148191 0,0302426 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 0,01148191 0,03022078 ! anchoring collagen GO:0030934 9 9 0,000 0,01148191 0,03019899 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 0,01148191 0,03017723 ! regulation of developmental growth GO:0048638 11 9 0,000 0,01148191 0,03015551 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 0,01148191 0,03013381 ! GMP binding GO:0019002 11 9 0,000 0,01148191 0,03011215 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 0,01148191 0,03009052 ! virus-host interaction GO:0019048 13 9 0,000 0,01148191 0,03006892 ! pentose-phosphate shunt GO:0006098 11 9 0,000 0,01148191 0,03004735 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 0,01148191 0,03002581 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 0,01148191 0,0300043 ! non-recombinational repair GO:0000726 10 9 0,000 0,01148191 0,02998282 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 0,01148191 0,02996137 ! nuclear telomere cap complex GO:0000783 10 9 0,000 0,01148191 0,02993996 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 0,01148191 0,02991857 ! social behavior GO:0035176 10 9 0,000 0,01148191 0,02989722 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 0,01148191 0,02987589 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 0,01148191 0,0298546 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 0,01148191 0,02983333 ! mating GO:0007618 11 9 0,000 0,01148191 0,0298121 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 0,01148191 0,0297909 ! rhythmic behavior GO:0007622 11 9 0,000 0,01148191 0,02976972 ! phospholipid efflux GO:0033700 10 9 0,000 0,01148191 0,02974858 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 0,01148191 0,02972747 ! poly-purine tract binding GO:0070717 9 9 0,000 0,01148191 0,02970638 ! T cell proliferation GO:0042098 10 9 0,000 0,01148191 0,02968533 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 0,01148191 0,02966431 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 0,01148191 0,02964331 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 0,01148191 0,02962235 ! interleukin-1 binding GO:0019966 10 9 0,000 0,01148191 0,02960141 ! glucosyltransferase activity GO:0046527 9 9 0,000 0,01148191 0,02958051 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 0,01148191 0,02955963 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 0,01148191 0,02953879 ! ovulation GO:0030728 9 9 0,000 0,01148191 0,02951797 ! acid phosphatase activity GO:0003993 18 9 0,000 0,01148191 0,02949718 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 0,01148191 0,02947642 ! ER overload response GO:0006983 11 9 0,000 0,01148191 0,0294557 ! B cell proliferation GO:0042100 10 9 0,000 0,01148191 0,029435 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 0,01148191 0,02941433 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 0,01148191 0,02939368 ! mannose metabolic process GO:0006013 13 9 0,000 0,01148191 0,02937307 ! lipid digestion GO:0044241 11 9 0,000 0,01148191 0,02935249 ! tumor necrosis factor binding GO:0043120 9 9 0,000 0,01148191 0,02933193 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 0,01148191 0,02931141 ! regulation of bone resorption GO:0045124 10 9 0,000 0,01148191 0,02929091 ! brain morphogenesis GO:0048854 9 9 0,000 0,01148191 0,02927044 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 0,01148191 0,02925 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 0,01148191 0,02922959 ! synaptic vesicle membrane GO:0030672 9 9 0,000 0,01148191 0,0292092 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 0,01148191 0,02918885 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 0,01148191 0,02916852 ! kinesin binding GO:0019894 9 9 0,000 0,01148191 0,02914822 ! multicellular organismal aging GO:0010259 18 9 0,000 0,01148191 0,02912795 ! Ran GTPase binding GO:0008536 11 9 0,000 0,01148191 0,02910771 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 0,01148191 0,0290875 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 0,01148191 0,02906731 ! mRNA polyadenylation GO:0006378 10 9 0,000 0,01148191 0,02904716 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 0,01148191 0,02902703 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 0,01148191 0,02900692 ! prostaglandin receptor activity GO:0004955 11 9 0,000 0,01148191 0,02898685 ! caspase inhibitor activity GO:0043027 9 9 0,000 0,01148191 0,0289668 ! adrenoceptor activity GO:0004935 12 9 0,000 0,01148191 0,02894679 ! regulation of isotype switching GO:0045191 9 9 0,000 0,01148191 0,02892679 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 0,01148191 0,02890683 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 0,01148191 0,0288869 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 0,01148191 0,02886699 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 0,01148191 0,02884711 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 0,01148191 0,02882725 ! Notch binding GO:0005112 10 9 0,000 0,01148191 0,02880743 ! ATPase regulator activity GO:0060590 10 9 0,000 0,01148191 0,02878763 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 0,01148191 0,02876786 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 0,01148191 0,02874811 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 0,01148191 0,02872839 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 0,01148191 0,0287087 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,01274985 0,03185715 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,01274985 0,03183535 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,01274985 0,03181357 ! sleep GO:0030431 11 10 0,000 0,01274985 0,03179183 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,01274985 0,03177011 ! lipid particle GO:0005811 10 10 0,000 0,01274985 0,03174843 ! filopodium assembly GO:0046847 14 10 0,000 0,01274985 0,03172677 ! UTP metabolic process GO:0046051 12 10 0,000 0,01274985 0,03170514 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,01274985 0,03168355 ! guanylate kinase activity GO:0004385 14 10 0,000 0,01274985 0,03166198 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,01274985 0,03164044 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,01274985 0,03161893 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,01274985 0,03159745 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,01274985 0,031576 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,01274985 0,03155458 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,01274985 0,03153318 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,01274985 0,03151182 ! lung alveolus development GO:0048286 11 10 0,000 0,01274985 0,03149048 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,01274985 0,03146918 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01274985 0,0314479 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,01274985 0,03142665 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,01274985 0,03140543 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,01274985 0,03138424 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,01274985 0,03136308 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,01274985 0,03134194 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,01274985 0,03132084 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,01274985 0,03129976 ! histidine metabolic process GO:0006547 10 10 0,000 0,01274985 0,03127871 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,01274985 0,03125769 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,01274985 0,0312367 ! death receptor activity GO:0005035 11 10 0,000 0,01274985 0,03121574 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,01274985 0,0311948 ! entry into host cell GO:0030260 11 10 0,000 0,01274985 0,03117389 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,01274985 0,03115301 ! filamentous actin GO:0031941 11 10 0,000 0,01274985 0,03113216 ! behavioral fear response GO:0001662 12 10 0,000 0,01274985 0,03111134 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,01274985 0,03109054 ! negative regulation of ossification GO:0030279 12 10 0,000 0,01274985 0,03106977 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,01274985 0,03104903 ! macrophage differentiation GO:0030225 11 10 0,000 0,01274985 0,03102832 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,01274985 0,03100763 ! recycling endosome membrane GO:0055038 11 10 0,000 0,01274985 0,03098697 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,01274985 0,03096634 ! snRNA metabolic process GO:0016073 10 10 0,000 0,01274985 0,03094574 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,01274985 0,03092516 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 0,01274985 0,03090462 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,01274985 0,03088409 ! positive regulation of Ras GTPase activity GO:0032320 14 10 0,000 0,01274985 0,0308636 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,01274985 0,03084313 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,01274985 0,03082269 ! induction of an organ GO:0001759 12 10 0,000 0,01274985 0,03080228 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,01274985 0,0307819 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,01274985 0,03076154 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,01274985 0,03074121 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,01274985 0,0307209 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,01274985 0,03070062 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,01274985 0,03068037 ! ribonuclease P activity GO:0004526 10 10 0,000 0,01274985 0,03066015 ! COPI vesicle coat GO:0030126 12 10 0,000 0,01274985 0,03063995 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,01274985 0,03061978 ! vitamin transporter activity GO:0051183 12 10 0,000 0,01274985 0,03059964 ! snRNA binding GO:0017069 11 10 0,000 0,01274985 0,03057952 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,01274985 0,03055943 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,01274985 0,03053936 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,01274985 0,03051932 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,01274985 0,03049931 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,01274985 0,03047932 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,01274985 0,03045936 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,01274985 0,03043943 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,01274985 0,03041952 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,01274985 0,03039964 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,01274985 0,03037978 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 0,01274985 0,03035995 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 0,01274985 0,03034015 ! extracellular matrix binding GO:0050840 11 10 0,000 0,01274985 0,03032037 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,01274985 0,03030062 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,01274985 0,03028089 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,01274985 0,03026119 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,01274985 0,03024151 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 0,01274985 0,03022186 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,01274985 0,03020224 ! thyroid gland development GO:0030878 12 10 0,000 0,01274985 0,03018264 ! DNA bending activity GO:0008301 11 10 0,000 0,01274985 0,03016306 ! regulation of phosphatase activity GO:0010921 10 10 0,000 0,01274985 0,03014352 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,01274985 0,03012399 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,01274985 0,0301045 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,01274985 0,03008502 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,01274985 0,03006558 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,01274985 0,03004615 ! regulation of glycolysis GO:0006110 11 10 0,000 0,01274985 0,03002676 ! nucleotidase activity GO:0008252 10 10 0,000 0,01274985 0,03000738 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,01274985 0,02998804 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,01274985 0,02996872 ! androgen metabolic process GO:0008209 11 10 0,000 0,01274985 0,02994942 ! lateral plasma membrane GO:0016328 13 10 0,000 0,01274985 0,02993015 ! MAP kinase kinase activity GO:0004708 12 10 0,000 0,01274985 0,0299109 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,01274985 0,02989167 ! startle response GO:0001964 13 10 0,000 0,01274985 0,02987248 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,01274985 0,0298533 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,01274985 0,02983415 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 0,01274985 0,02981503 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,01274985 0,02979593 ! spinal cord patterning GO:0021511 12 10 0,000 0,01274985 0,02977685 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,01274985 0,0297578 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,01274985 0,02973878 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,01274985 0,02971977 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 0,01274985 0,0297008 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,01274985 0,02968184 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,01274985 0,02966291 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,01274985 0,02964401 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,01274985 0,02962512 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,01274985 0,02960627 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,01274985 0,02958743 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,01274985 0,02956862 ! neuromuscular junction development GO:0007528 12 10 0,000 0,01274985 0,02954984 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,01274985 0,02953108 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,01274985 0,02951234 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,01274985 0,02949362 ! signalosome GO:0008180 10 10 0,000 0,01274985 0,02947493 ! lysophospholipase activity GO:0004622 19 10 0,000 0,01274985 0,02945627 ! prefoldin complex GO:0016272 10 10 0,000 0,01274985 0,02943762 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,01274985 0,029419 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,01274985 0,02940041 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,01274985 0,02938184 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,01274985 0,02936329 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,01274985 0,02934476 ! gland morphogenesis GO:0022612 11 10 0,000 0,01274985 0,02932626 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,01274985 0,02930778 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,01274985 0,02928932 ! peptide transporter activity GO:0015197 10 10 0,000 0,01274985 0,02927089 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,01274985 0,02925248 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,01274985 0,0292341 ! muscle maintenance GO:0046716 10 10 0,000 0,01274985 0,02921573 ! acid secretion GO:0046717 12 10 0,000 0,01274985 0,02919739 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,01274985 0,02917908 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,01274985 0,02916078 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,01274985 0,02914251 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,01274985 0,02912426 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,01274985 0,02910604 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,01274985 0,02908783 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,01274985 0,02906965 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,01274985 0,0290515 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 0,01274985 0,02903336 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,01274985 0,02901525 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,01274985 0,02899716 ! water channel activity GO:0015250 15 10 0,000 0,01274985 0,02897909 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,01274985 0,02896105 ! regulation of embryonic development GO:0045995 12 10 0,000 0,01274985 0,02894303 ! acrosome reaction GO:0007340 12 10 0,000 0,01274985 0,02892503 ! mitochondrion localization GO:0051646 10 10 0,000 0,01274985 0,02890705 ! cilium part GO:0044441 10 10 0,000 0,01274985 0,0288891 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,01401623 0,0317388 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,01401623 0,03171911 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,01401623 0,03169945 ! cadmium ion binding GO:0046870 15 11 0,000 0,01401623 0,03167981 ! hemoglobin complex GO:0005833 13 11 0,000 0,01401623 0,03166019 ! CTP metabolic process GO:0046036 13 11 0,000 0,01401623 0,0316406 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,01401623 0,03162103 ! response to pain GO:0048265 12 11 0,000 0,01401623 0,03160149 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,01401623 0,03158197 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,01401623 0,03156247 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,01401623 0,031543 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,01401623 0,03152356 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01401623 0,03150413 ! peptide antigen binding GO:0042605 14 11 0,000 0,01401623 0,03148473 ! polyamine metabolic process GO:0006595 11 11 0,000 0,01401623 0,03146536 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,01401623 0,03144601 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,01401623 0,03142668 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,01401623 0,03140738 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,01401623 0,0313881 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,01401623 0,03136884 ! protein homotetramerization GO:0051289 13 11 0,000 0,01401623 0,03134961 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,01401623 0,0313304 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,01401623 0,03131121 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,01401623 0,03129205 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,01401623 0,03127291 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,01401623 0,03125379 ! response to dsRNA GO:0043331 21 11 0,000 0,01401623 0,0312347 ! response to amine stimulus GO:0014075 15 11 0,000 0,01401623 0,03121563 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,01401623 0,03119659 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,01401623 0,03117757 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,01401623 0,03115857 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,01401623 0,03113959 ! retinal binding GO:0016918 11 11 0,000 0,01401623 0,03112064 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,01401623 0,03110171 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,01401623 0,0310828 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,01401623 0,03106392 ! autonomic nervous system development GO:0048483 12 11 0,000 0,01401623 0,03104506 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,01401623 0,03102622 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,01401623 0,0310074 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,01401623 0,03098861 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,01401623 0,03096984 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,01401623 0,03095109 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,01401623 0,03093237 ! regulation of epidermis development GO:0045682 14 11 0,000 0,01401623 0,03091367 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,01401623 0,03089499 ! midbrain development GO:0030901 12 11 0,000 0,01401623 0,03087633 ! musculoskeletal movement GO:0050881 12 11 0,000 0,01401623 0,0308577 GO:0050879|multicellular organismal movement, ! regulation of RNA stability GO:0043487 13 11 0,000 0,01401623 0,03083909 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,01401623 0,0308205 ! cell killing GO:0001906 13 11 0,000 0,01401623 0,03080193 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,01401623 0,03078339 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,01401623 0,03076487 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,01401623 0,03074637 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 0,01401623 0,03072789 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 0,01401623 0,03070943 ! folic acid binding GO:0005542 12 11 0,000 0,01401623 0,030691 ! mRNA 3'-end processing GO:0031124 12 11 0,000 0,01401623 0,03067259 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,01401623 0,0306542 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,01401623 0,03063583 ! microspike assembly GO:0030035 15 11 0,000 0,01401623 0,03061749 ! lamellipodium assembly GO:0030032 22 11 0,000 0,01401623 0,03059917 ! fibrillar collagen GO:0005583 12 11 0,000 0,01401623 0,03058087 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,01401623 0,03056259 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,01401623 0,03054433 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,01401623 0,03052609 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,01401623 0,03050788 ! synaptonemal complex GO:0000795 11 11 0,000 0,01401623 0,03048969 ! reproductive cellular process GO:0048610 13 11 0,000 0,01401623 0,03047152 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,01401623 0,03045337 ! Golgi vesicle budding GO:0048194 12 11 0,000 0,01401623 0,03043524 ! response to cAMP GO:0051591 11 11 0,000 0,01401623 0,03041714 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,01401623 0,03039905 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,01401623 0,03038099 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01401623 0,03036295 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,01401623 0,03034493 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,01401623 0,03032693 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,01401623 0,03030895 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 0,01401623 0,030291 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,01401623 0,03027307 ! drug transport GO:0015893 12 11 0,000 0,01401623 0,03025515 ! FMN binding GO:0010181 12 11 0,000 0,01401623 0,03023726 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,01401623 0,03021939 ! water transporter activity GO:0005372 17 11 0,000 0,01401623 0,03020154 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,01401623 0,03018371 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01401623 0,0301659 ! multicellular organism growth GO:0035264 12 11 0,000 0,01401623 0,03014812 ! integrator complex GO:0032039 11 11 0,000 0,01401623 0,03013035 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,01401623 0,03011261 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,01401623 0,03009488 ! brush border membrane GO:0031526 12 11 0,000 0,01401623 0,03007718 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,01401623 0,0300595 ! negative regulation of caspase activity GO:0043154 12 11 0,000 0,01401623 0,03004184 ! macroautophagy GO:0016236 12 11 0,000 0,01401623 0,0300242 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,01401623 0,03000658 ! neuromuscular junction GO:0031594 12 11 0,000 0,01401623 0,02998898 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,01401623 0,0299714 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 0,01401623 0,02995384 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,01401623 0,0299363 ! response to antibiotic GO:0046677 13 11 0,000 0,01401623 0,02991879 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,01401623 0,02990129 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,01401623 0,02988381 ! proteasome accessory complex GO:0022624 11 11 0,000 0,01401623 0,02986636 ! neuroblast proliferation GO:0007405 13 11 0,000 0,01401623 0,02984892 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,01401623 0,02983151 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,01401623 0,02981411 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,01401623 0,02979674 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,01401623 0,02977939 ! male genitalia development GO:0030539 15 11 0,000 0,01401623 0,02976205 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,01401623 0,02974474 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,01401623 0,02972745 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,01401623 0,02971017 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,01401623 0,02969292 ! arylsulfatase activity GO:0004065 12 11 0,000 0,01401623 0,02967569 ! sterol transporter activity GO:0015248 11 11 0,000 0,01401623 0,02965847 ! response to nicotine GO:0035094 13 11 0,000 0,01401623 0,02964128 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01401623 0,02962411 ! rRNA transcription GO:0009303 12 12 0,000 0,01528105 0,03227868 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,01528105 0,03226 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,01528105 0,03224135 ! superoxide anion generation GO:0042554 12 12 0,000 0,01528105 0,03222271 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,01528105 0,03220409 ! regulation of S phase GO:0033261 16 12 0,000 0,01528105 0,0321855 ! regulation of chemokine production GO:0032642 13 12 0,000 0,01528105 0,03216693 ! male meiosis GO:0007140 12 12 0,000 0,01528105 0,03214838 ! signal complex assembly GO:0007172 15 12 0,000 0,01528105 0,03212985 ! positive regulation of GTPase activity GO:0043547 17 12 0,000 0,01528105 0,03211134 ! GTP metabolic process GO:0046039 14 12 0,000 0,01528105 0,03209285 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,01528105 0,03207439 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,01528105 0,03205594 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,01528105 0,03203752 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,01528105 0,03201912 ! cartilage condensation GO:0001502 14 12 0,000 0,01528105 0,03200074 ! polysome GO:0005844 14 12 0,000 0,01528105 0,03198238 ! hippocampus development GO:0021766 13 12 0,000 0,01528105 0,03196404 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,01528105 0,03194572 ! beta-amyloid binding GO:0001540 12 12 0,000 0,01528105 0,03192743 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,01528105 0,03190915 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,01528105 0,0318909 ! regulation of exit from mitosis GO:0007096 31 12 0,000 0,01528105 0,03187266 ! chylomicron GO:0042627 13 12 0,000 0,01528105 0,03185445 ! T cell selection GO:0045058 22 12 0,000 0,01528105 0,03183626 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,01528105 0,03181809 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,01528105 0,03179994 ! WW domain binding GO:0050699 12 12 0,000 0,01528105 0,03178181 ! methionine metabolic process GO:0006555 14 12 0,000 0,01528105 0,0317637 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,01528105 0,03174561 ! glycine metabolic process GO:0006544 14 12 0,000 0,01528105 0,03172754 ! plasma membrane organization GO:0007009 12 12 0,000 0,01528105 0,03170949 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01528105 0,03169147 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,01528105 0,03167346 ! Golgi organization GO:0007030 15 12 0,000 0,01528105 0,03165547 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01528105 0,03163751 ! mitotic spindle organization GO:0007052 13 12 0,000 0,01528105 0,03161956 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,01528105 0,03160164 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,01528105 0,03158373 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,01528105 0,03156585 ! temperature homeostasis GO:0001659 13 12 0,000 0,01528105 0,03154798 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,01528105 0,03153014 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01528105 0,03151232 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01528105 0,03149451 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,01528105 0,03147673 ! axon cargo transport GO:0008088 13 12 0,000 0,01528105 0,03145897 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,01528105 0,03144122 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,01528105 0,0314235 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,01528105 0,0314058 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,01528105 0,03138811 ! basal lamina GO:0005605 12 12 0,000 0,01528105 0,03137045 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,01528105 0,03135281 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,01528105 0,03133518 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,01528105 0,03131758 ! biomineral formation GO:0031214 14 12 0,000 0,01528105 0,03129999 ! water homeostasis GO:0030104 12 12 0,000 0,01528105 0,03128243 ! promoter binding GO:0010843 14 12 0,000 0,01528105 0,03126488 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,01528105 0,03124736 ! intestinal absorption GO:0050892 14 12 0,000 0,01528105 0,03122985 ! oocyte differentiation GO:0009994 13 12 0,000 0,01528105 0,03121237 ! oxygen transport GO:0015671 13 12 0,000 0,01528105 0,0311949 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,01528105 0,03117745 ! cholesterol efflux GO:0033344 13 12 0,000 0,01528105 0,03116003 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,01528105 0,03114262 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,01528105 0,03112523 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,01528105 0,03110786 ! tropomyosin binding GO:0005523 12 12 0,000 0,01528105 0,03109051 ! blastocyst formation GO:0001825 13 12 0,000 0,01528105 0,03107318 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,01528105 0,03105587 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,01528105 0,03103858 ! mannose binding GO:0005537 13 12 0,000 0,01528105 0,03102131 ! phosphoprotein binding GO:0051219 14 12 0,000 0,01528105 0,03100405 ! defense response to fungus GO:0050832 12 12 0,000 0,01528105 0,03098682 ! embryonic placenta development GO:0001892 16 12 0,000 0,01528105 0,0309696 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01528105 0,03095241 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,01528105 0,03093523 ! acyl-CoA binding GO:0000062 12 12 0,000 0,01528105 0,03091807 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,01528105 0,03090094 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,01528105 0,03088382 ! copper ion transport GO:0006825 12 12 0,000 0,01528105 0,03086672 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,01528105 0,03084963 ! inositol metabolic process GO:0006020 21 12 0,000 0,01528105 0,03083257 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,01528105 0,03081553 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,01528105 0,0307985 ! protein complex disassembly GO:0043241 15 12 0,000 0,01528105 0,0307815 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,01528105 0,03076451 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,01528105 0,03074754 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,01528105 0,03073059 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,01528105 0,03071366 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,01528105 0,03069674 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,01528105 0,03067985 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,01528105 0,03066297 ! endoderm development GO:0007492 13 12 0,000 0,01528105 0,03064612 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,01528105 0,03062928 ! focal adhesion formation GO:0048041 16 12 0,000 0,01528105 0,03061246 ! T cell receptor complex GO:0042101 31 12 0,000 0,01528105 0,03059566 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,01528105 0,03057887 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,01528105 0,03056211 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,01528105 0,03054536 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,01528105 0,03052864 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,01528105 0,03051193 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,01528105 0,03049523 ! retinol binding GO:0019841 12 12 0,000 0,01528105 0,03047856 ! regulation of organ growth GO:0046620 12 12 0,000 0,01528105 0,03046191 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,01528105 0,03044527 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,01528105 0,03042865 ! histone acetylation GO:0016573 13 12 0,000 0,01528105 0,03041205 ! ribosome binding GO:0043022 13 12 0,000 0,01528105 0,03039547 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,01528105 0,0303789 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,01528105 0,03036236 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,01528105 0,03034583 ! tissue regeneration GO:0042246 12 12 0,000 0,01528105 0,03032932 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,01528105 0,03031283 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,01528105 0,03029635 ! germ cell nucleus GO:0043073 14 12 0,000 0,01528105 0,0302799 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,01528105 0,03026346 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,01528105 0,03024704 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01528105 0,03023063 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01528105 0,03021425 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,01528105 0,03019788 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,01528105 0,03018153 ! dopamine metabolic process GO:0042417 15 12 0,000 0,01528105 0,0301652 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,01528105 0,03014888 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,01528105 0,03013259 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,01528105 0,03011631 ! bacterial binding GO:0008367 14 12 0,000 0,01528105 0,03010005 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01528105 0,0300838 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,01528105 0,03006758 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,01528105 0,03005137 ! localization within membrane GO:0051668 13 12 0,000 0,01528105 0,03003518 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,01528105 0,030019 ! axoneme part GO:0044447 12 12 0,000 0,01528105 0,03000285 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01654432 0,03246568 ! neuron maturation GO:0042551 14 13 0,000 0,01654432 0,03244822 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01654432 0,03243079 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01654432 0,03241337 ! bone remodeling GO:0046849 14 13 0,000 0,01654432 0,03239597 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01654432 0,03237859 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01654432 0,03236123 ! striated muscle thin filament GO:0005865 14 13 0,000 0,01654432 0,03234389 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01654432 0,03232657 ! organelle fusion GO:0048284 16 13 0,000 0,01654432 0,03230926 ! palate development GO:0060021 15 13 0,000 0,01654432 0,03229197 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01654432 0,0322747 ! arginine metabolic process GO:0006525 14 13 0,000 0,01654432 0,03225745 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01654432 0,03224022 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01654432 0,03222301 ! response to retinoic acid GO:0032526 17 13 0,000 0,01654432 0,03220581 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01654432 0,03218864 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01654432 0,03217148 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01654432 0,03215434 ! fear response GO:0042596 15 13 0,000 0,01654432 0,03213722 ! epithelial cell development GO:0002064 22 13 0,000 0,01654432 0,03212012 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,01654432 0,03210303 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01654432 0,03208596 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01654432 0,03206891 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01654432 0,03205188 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01654432 0,03203487 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01654432 0,03201788 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,01654432 0,0320009 ! cranial nerve development GO:0021545 15 13 0,000 0,01654432 0,03198394 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,01654432 0,031967 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01654432 0,03195008 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,01654432 0,03193317 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01654432 0,03191629 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01654432 0,03189942 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01654432 0,03188257 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01654432 0,03186573 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01654432 0,03184892 ! NADP metabolic process GO:0006739 15 13 0,000 0,01654432 0,03183212 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01654432 0,03181534 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01654432 0,03179858 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01654432 0,03178183 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01654432 0,0317651 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01654432 0,03174839 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01654432 0,0317317 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01654432 0,03171503 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01654432 0,03169837 ! ADP binding GO:0043531 15 13 0,000 0,01654432 0,03168173 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01654432 0,03166511 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01654432 0,0316485 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01654432 0,03163192 ! neuron fate specification GO:0048665 25 13 0,000 0,01654432 0,03161535 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01654432 0,03159879 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01654432 0,03158226 ! water transport GO:0006833 18 13 0,000 0,01654432 0,03156574 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01654432 0,03154924 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01654432 0,03153276 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01654432 0,03151629 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01654432 0,03149984 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01654432 0,03148341 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,01654432 0,031467 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01654432 0,0314506 ! myoblast differentiation GO:0045445 15 13 0,000 0,01654432 0,03143422 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01654432 0,03141785 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01654432 0,03140151 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01654432 0,03138518 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01654432 0,03136887 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,01654432 0,03135257 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01654432 0,03133629 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01654432 0,03132003 ! exocrine system development GO:0035272 14 13 0,000 0,01654432 0,03130378 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01654432 0,03128756 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01654432 0,03127135 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01654432 0,03125515 ! L-glutamate transport GO:0015813 14 13 0,000 0,01654432 0,03123897 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01654432 0,03122281 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01654432 0,03120667 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01654432 0,03119054 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01654432 0,03117443 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01654432 0,03115834 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,01654432 0,03114226 ! genitalia development GO:0048806 18 13 0,000 0,01654432 0,0311262 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01654432 0,03111015 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01654432 0,03109413 ! MHC class I protein binding GO:0042288 23 13 0,000 0,01654432 0,03107811 ! histone deacetylation GO:0016575 14 13 0,000 0,01654432 0,03106212 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01654432 0,03104614 ! DNA methylation GO:0006306 15 13 0,000 0,01654432 0,03103018 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01654432 0,03101423 ! chromatin silencing GO:0006342 13 13 0,000 0,01654432 0,0309983 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01654432 0,03098239 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01654432 0,03096649 ! T cell homeostasis GO:0043029 14 13 0,000 0,01654432 0,03095061 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01654432 0,03093475 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01654432 0,0309189 ! response to gamma radiation GO:0010332 14 13 0,000 0,01654432 0,03090307 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01654432 0,03088726 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01654432 0,03087146 ! purine base metabolic process GO:0006144 15 13 0,000 0,01654432 0,03085567 ! cAMP binding GO:0030552 15 13 0,000 0,01654432 0,03083991 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01654432 0,03082416 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01654432 0,03080842 ! regulation of axon extension GO:0030516 16 13 0,000 0,01654432 0,0307927 ! drug transporter activity GO:0015238 14 13 0,000 0,01654432 0,030777 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01654432 0,03076131 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01654432 0,03074564 ! response to cold GO:0009409 13 13 0,000 0,01654432 0,03072999 ! cadherin binding GO:0045296 16 13 0,000 0,01654432 0,03071435 ! tRNA modification GO:0006400 14 14 0,000 0,01780604 0,0330399 ! cis-Golgi network GO:0005801 16 14 0,000 0,01780604 0,0330231 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,01780604 0,03300632 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,01780604 0,03298956 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,01780604 0,03297281 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,01780604 0,03295608 ! peroxisomal transport GO:0043574 14 14 0,000 0,01780604 0,03293937 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,01780604 0,03292268 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,01780604 0,032906 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,01780604 0,03288934 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,01780604 0,03287269 ! negative regulation of peptidase activity GO:0010466 16 14 0,000 0,01780604 0,03285606 ! positive regulation of cell growth GO:0030307 15 14 0,000 0,01780604 0,03283945 ! caspase activator activity GO:0008656 16 14 0,000 0,01780604 0,03282286 ! MHC class II protein complex GO:0042613 19 14 0,000 0,01780604 0,03280628 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01780604 0,03278972 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,01780604 0,03277318 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,01780604 0,03275665 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,01780604 0,03274014 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01780604 0,03272365 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,01780604 0,03270717 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,01780604 0,03269071 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,01780604 0,03267427 ! response to vitamin A GO:0033189 18 14 0,000 0,01780604 0,03265784 ! actin filament bundle formation GO:0051017 16 14 0,000 0,01780604 0,03264143 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,01780604 0,03262503 ! plasma membrane fusion GO:0045026 15 14 0,000 0,01780604 0,03260865 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,01780604 0,03259229 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 14 14 0,000 0,01780604 0,03257595 ! presynaptic membrane GO:0042734 14 14 0,000 0,01780604 0,03255962 ! negative regulation of immune response GO:0050777 21 14 0,000 0,01780604 0,03254331 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,01780604 0,03252701 ! neural crest cell migration GO:0001755 15 14 0,000 0,01780604 0,03251073 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,01780604 0,03249447 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,01780604 0,03247822 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,01780604 0,03246199 ! cofactor transport GO:0051181 16 14 0,000 0,01780604 0,03244577 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01780604 0,03242958 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,01780604 0,03241339 ! cobalt ion binding GO:0050897 14 14 0,000 0,01780604 0,03239723 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01780604 0,03238108 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,01780604 0,03236494 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,01780604 0,03234882 ! gas transport GO:0015669 15 14 0,000 0,01780604 0,03233272 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,01780604 0,03231664 ! heme biosynthetic process GO:0006783 14 14 0,000 0,01780604 0,03230057 ! release of cytochrome c from mitochondria GO:0001836 26 14 0,000 0,01780604 0,03228451 ! cerebellar cortex development GO:0021695 16 14 0,000 0,01780604 0,03226847 ! insulin secretion GO:0030073 17 14 0,000 0,01780604 0,03225245 ! tRNA binding GO:0000049 16 14 0,000 0,01780604 0,03223645 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,01780604 0,03222046 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,01780604 0,03220448 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,01780604 0,03218852 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,01780604 0,03217258 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,01780604 0,03215665 ! MAP kinase activity GO:0004707 16 14 0,000 0,01780604 0,03214074 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,01780604 0,03212485 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,01780604 0,03210897 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,01780604 0,0320931 ! C-C chemokine binding GO:0019957 15 14 0,000 0,01780604 0,03207725 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,01780604 0,03206142 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,01780604 0,0320456 ! response to osmotic stress GO:0006970 17 14 0,000 0,01780604 0,0320298 ! fructose metabolic process GO:0006000 15 14 0,000 0,01780604 0,03201402 ! telomeric DNA binding GO:0042162 17 14 0,000 0,01780604 0,03199825 ! monoamine transport GO:0015844 15 14 0,000 0,01780604 0,03198249 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,01780604 0,03196675 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01780604 0,03195103 ! dendritic spine GO:0043197 15 14 0,000 0,01780604 0,03193532 ! stem cell development GO:0048864 14 14 0,000 0,01780604 0,03191963 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,01780604 0,03190395 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,01780604 0,03188829 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,01780604 0,03187264 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,01780604 0,03185701 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01780604 0,03184139 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,01780604 0,03182579 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01780604 0,03181021 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,01780604 0,03179464 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,01780604 0,03177908 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,01780604 0,03176354 ! mannosidase activity GO:0015923 19 14 0,000 0,01780604 0,03174802 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,01780604 0,03173251 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,01780604 0,03171701 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,01780604 0,03170153 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,01780604 0,03168607 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,01780604 0,03167062 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01780604 0,03165519 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,01780604 0,03163977 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,01780604 0,03162436 ! sperm-egg recognition GO:0035036 17 14 0,000 0,01780604 0,03160897 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,01780604 0,0315936 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,01780604 0,03157824 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,01780604 0,0315629 ! positive regulation of translation GO:0045727 17 15 0,000 0,01906621 0,03378024 ! nuclear replication fork GO:0043596 26 15 0,000 0,01906621 0,03376385 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,01906621 0,03374746 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,01906621 0,0337311 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,01906621 0,03371475 ! endothelial cell migration GO:0043542 16 15 0,000 0,01906621 0,03369841 ! lipid phosphorylation GO:0046834 19 15 0,000 0,01906621 0,03368209 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01906621 0,03366579 ! response to vitamin GO:0033273 19 15 0,000 0,01906621 0,0336495 ! gene silencing by RNA GO:0031047 17 15 0,000 0,01906621 0,03363323 ! striated muscle thick filament GO:0005863 16 15 0,000 0,01906621 0,03361698 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,01906621 0,03360074 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,01906621 0,03358451 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,01906621 0,0335683 ! glutamate metabolic process GO:0006536 17 15 0,000 0,01906621 0,03355211 ! pituitary gland development GO:0021983 16 15 0,000 0,01906621 0,03353593 ! cholesterol binding GO:0015485 15 15 0,000 0,01906621 0,03351977 ! NAD metabolic process GO:0019674 17 15 0,000 0,01906621 0,03350362 ! protease binding GO:0002020 20 15 0,000 0,01906621 0,03348749 ! regulation of heart rate GO:0002027 20 15 0,000 0,01906621 0,03347138 ! actin filament bundle GO:0032432 18 15 0,000 0,01906621 0,03345528 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,01906621 0,03343919 ! regulation of exocytosis GO:0017157 16 15 0,000 0,01906621 0,03342313 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01906621 0,03340707 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,01906621 0,03339103 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,01906621 0,03337501 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,01906621 0,033359 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,01906621 0,03334301 ! neuron recognition GO:0008038 18 15 0,000 0,01906621 0,03332704 ! regulation of Rho GTPase activity GO:0032319 18 15 0,000 0,01906621 0,03331107 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,01906621 0,03329513 ! filopodium GO:0030175 17 15 0,000 0,01906621 0,0332792 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,01906621 0,03326328 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,01906621 0,03324738 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,01906621 0,0332315 ! peptide hormone binding GO:0017046 16 15 0,000 0,01906621 0,03321563 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,01906621 0,03319977 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,01906621 0,03318393 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,01906621 0,03316811 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,01906621 0,0331523 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,01906621 0,0331365 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,01906621 0,03312073 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,01906621 0,03310496 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,01906621 0,03308921 ! developmental induction GO:0031128 17 15 0,000 0,01906621 0,03307348 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,01906621 0,03305776 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,01906621 0,03304205 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,01906621 0,03302636 ! lactation GO:0007595 17 15 0,000 0,01906621 0,03301069 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,01906621 0,03299503 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01906621 0,03297939 ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,01906621 0,03296376 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,01906621 0,03294814 ! sulfate transport GO:0008272 16 15 0,000 0,01906621 0,03293254 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,01906621 0,03291695 ! bile acid metabolic process GO:0008206 17 15 0,000 0,01906621 0,03290138 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,01906621 0,03288583 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,01906621 0,03287029 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,01906621 0,03285476 ! heart looping GO:0001947 18 15 0,000 0,01906621 0,03283925 ! protein kinase C activity GO:0004697 17 15 0,000 0,01906621 0,03282375 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,01906621 0,03280827 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,01906621 0,0327928 ! pigmentation during development GO:0048066 17 15 0,000 0,01906621 0,03277734 ! cytokine metabolic process GO:0042107 15 15 0,000 0,01906621 0,0327619 ! vesicle coating GO:0006901 17 15 0,000 0,01906621 0,03274648 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,01906621 0,03273107 ! neutral amino acid transport GO:0015804 18 15 0,000 0,01906621 0,03271567 ! L-amino acid transport GO:0015807 16 15 0,000 0,01906621 0,03270029 ! microfilament motor activity GO:0000146 15 15 0,000 0,01906621 0,03268493 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,01906621 0,03266957 ! regulation of vasodilation GO:0042312 25 15 0,000 0,01906621 0,03265424 ! DNA replication initiation GO:0006270 15 15 0,000 0,01906621 0,03263891 ! taste receptor activity GO:0008527 15 15 0,000 0,01906621 0,0326236 ! cellular pigmentation GO:0033059 16 15 0,000 0,01906621 0,03260831 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,01906621 0,03259303 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,01906621 0,03257776 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,01906621 0,03256251 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,01906621 0,03254727 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,01906621 0,03253205 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,01906621 0,03251684 ! ion gated channel activity GO:0022839 17 15 0,000 0,01906621 0,03250165 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,01906621 0,03248647 ! receptor activator activity GO:0030546 17 15 0,000 0,01906621 0,0324713 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,01906621 0,03245615 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,01906621 0,03244101 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,01906621 0,03242589 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,01906621 0,03241078 ! peptide hormone processing GO:0016486 19 15 0,000 0,01906621 0,03239568 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01906621 0,0323806 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,02032482 0,03450207 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,02032482 0,03448603 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,02032482 0,03446999 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,02032482 0,03445398 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,02032482 0,03443797 ! kinesin complex GO:0005871 16 16 0,000 0,02032482 0,03442198 ! photoreceptor cell development GO:0042461 22 16 0,000 0,02032482 0,03440601 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,02032482 0,03439005 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,02032482 0,03437411 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,02032482 0,03435818 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,02032482 0,03434227 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,02032482 0,03432637 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,02032482 0,03431048 ! lysosomal transport GO:0007041 16 16 0,000 0,02032482 0,03429461 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,02032482 0,03427876 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,02032482 0,03426292 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,02032482 0,03424709 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,02032482 0,03423128 ! myofibril assembly GO:0030239 17 16 0,000 0,02032482 0,03421548 GO:0055002|striated muscle cell development, ! G1 phase GO:0051318 17 16 0,000 0,02032482 0,0341997 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,02032482 0,03418393 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,02032482 0,03416818 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,02032482 0,03415244 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,02032482 0,03413672 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,02032482 0,03412101 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,02032482 0,03410531 ! steroid catabolic process GO:0006706 18 16 0,000 0,02032482 0,03408963 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,02032482 0,03407397 ! cell-cell recognition GO:0009988 19 16 0,000 0,02032482 0,03405832 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,02032482 0,03404268 ! spleen development GO:0048536 19 16 0,000 0,02032482 0,03402706 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,02032482 0,03401145 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,02032482 0,03399585 ! neural tube closure GO:0001843 19 16 0,000 0,02032482 0,03398027 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,02032482 0,03396471 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,02032482 0,03394916 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,02032482 0,03393362 ! viral genome replication GO:0019079 16 16 0,000 0,02032482 0,03391809 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,02032482 0,03390259 ! memory GO:0007613 18 16 0,000 0,02032482 0,03388709 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,02032482 0,03387161 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02032482 0,03385614 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,02032482 0,03384069 ! glycoprotein binding GO:0001948 19 16 0,000 0,02032482 0,03382525 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,02032482 0,03380983 ! syntaxin binding GO:0019905 18 16 0,000 0,02032482 0,03379442 ! myosin binding GO:0017022 17 16 0,000 0,02032482 0,03377902 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,02032482 0,03376364 ! fucose metabolic process GO:0006004 18 16 0,000 0,02032482 0,03374827 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,02032482 0,03373292 ! membrane budding GO:0006900 18 16 0,000 0,02032482 0,03371758 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,02032482 0,03370225 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,02032482 0,03368694 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,02032482 0,03367164 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,02032482 0,03365636 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,02032482 0,03364109 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,02032482 0,03362583 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,02032482 0,03361059 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,02032482 0,03359536 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,02032482 0,03358014 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,02032482 0,03356494 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,02032482 0,03354975 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,02032482 0,03353458 ! axoneme GO:0005930 16 16 0,000 0,02032482 0,03351942 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,02032482 0,03350427 ! anion exchanger activity GO:0015380 17 17 0,000 0,02158189 0,03556041 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,02158189 0,03554435 ! skin development GO:0043588 20 17 0,000 0,02158189 0,03552831 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,02158189 0,03551229 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,02158189 0,03549628 ! glial cell development GO:0021782 17 17 0,000 0,02158189 0,03548028 ! limbic system development GO:0021761 18 17 0,000 0,02158189 0,0354643 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,02158189 0,03544833 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,02158189 0,03543238 ! ephrin receptor activity GO:0005003 21 17 0,000 0,02158189 0,03541644 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,02158189 0,03540051 ! glutamine metabolic process GO:0006541 26 17 0,000 0,02158189 0,0353846 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,02158189 0,03536871 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,02158189 0,03535282 ! signal sequence binding GO:0005048 18 17 0,000 0,02158189 0,03533696 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,02158189 0,0353211 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,02158189 0,03530526 ! organelle subcompartment GO:0031984 19 17 0,000 0,02158189 0,03528944 ! regulation of dephosphorylation GO:0035303 20 17 0,000 0,02158189 0,03527363 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,02158189 0,03525783 ! membrane depolarization GO:0051899 19 17 0,000 0,02158189 0,03524205 ! oogenesis GO:0048477 20 17 0,000 0,02158189 0,03522628 ! nuclear outer membrane GO:0005640 21 17 0,000 0,02158189 0,03521053 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,02158189 0,03519479 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,02158189 0,03517906 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,02158189 0,03516335 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,02158189 0,03514765 ! organic cation transport GO:0015695 17 17 0,000 0,02158189 0,03513197 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,02158189 0,0351163 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,02158189 0,03510064 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,02158189 0,035085 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,02158189 0,03506937 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,02158189 0,03505376 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,02158189 0,03503816 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,02158189 0,03502257 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,02158189 0,035007 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02158189 0,03499144 ! lipid localization GO:0010876 19 17 0,000 0,02158189 0,03497589 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,02158189 0,03496036 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,02158189 0,03494485 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,02158189 0,03492934 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,02158189 0,03491385 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,02158189 0,03489838 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,02158189 0,03488292 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,02158189 0,03486747 ! response to hexose stimulus GO:0009746 20 17 0,000 0,02158189 0,03485203 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,02158189 0,03483661 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,02158189 0,0348212 ! AMP binding GO:0016208 19 17 0,000 0,02158189 0,03480581 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,02158189 0,03479043 ! receptor metabolic process GO:0043112 20 17 0,000 0,02158189 0,03477506 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,02158189 0,03475971 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,02158189 0,03474437 ! alcohol binding GO:0043178 20 17 0,000 0,02158189 0,03472904 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,02158189 0,03471373 ! visual learning GO:0008542 31 17 0,000 0,02158189 0,03469843 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,02158189 0,03468315 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,02158189 0,03466787 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,02158189 0,03465261 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,02158189 0,03463737 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,02158189 0,03462214 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,02158189 0,03460692 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,02158189 0,03459171 ! translation elongation factor activity GO:0003746 19 17 0,000 0,02158189 0,03457652 ! histone binding GO:0042393 26 17 0,000 0,02158189 0,03456134 ! cilium assembly GO:0042384 18 17 0,000 0,02158189 0,03454618 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,02158189 0,03453103 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,02158189 0,03451589 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,02158189 0,03450076 ! protein secretion GO:0009306 19 18 0,000 0,02283741 0,03649185 ! positive regulation of cell size GO:0045793 19 18 0,000 0,02283741 0,03647587 ! positive regulation of ossification GO:0045778 19 18 0,000 0,02283741 0,03645991 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,02283741 0,03644396 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,02283741 0,03642802 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,02283741 0,0364121 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,02283741 0,03639619 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,02283741 0,0363803 ! cAMP metabolic process GO:0046058 18 18 0,000 0,02283741 0,03636442 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,02283741 0,03634855 ! cornified envelope GO:0001533 22 18 0,000 0,02283741 0,0363327 ! retinoid metabolic process GO:0001523 19 18 0,000 0,02283741 0,03631686 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,02283741 0,03630104 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,02283741 0,03628523 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,02283741 0,03626943 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,02283741 0,03625365 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,02283741 0,03623788 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,02283741 0,03622212 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,02283741 0,03620638 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,02283741 0,03619065 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,02283741 0,03617494 ! primary neural tube formation GO:0014020 21 18 0,000 0,02283741 0,03615924 ! recycling endosome GO:0055037 22 18 0,000 0,02283741 0,03614355 ! muscle cell development GO:0055001 20 18 0,000 0,02283741 0,03612788 ! kinase activator activity GO:0019209 22 18 0,000 0,02283741 0,03611222 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,02283741 0,03609657 ! cerebellum development GO:0021549 20 18 0,000 0,02283741 0,03608094 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,02283741 0,03606532 ! somitogenesis GO:0001756 20 18 0,000 0,02283741 0,03604971 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,02283741 0,03603412 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,02283741 0,03601854 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,02283741 0,03600298 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,02283741 0,03598742 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,02283741 0,03597188 ! basal plasma membrane GO:0009925 21 18 0,000 0,02283741 0,03595636 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,02283741 0,03594085 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,02283741 0,03592535 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,02283741 0,03590986 ! negative regulation of translation GO:0017148 31 18 0,000 0,02283741 0,03589439 ! regulation of cell killing GO:0031341 24 18 0,000 0,02283741 0,03587893 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,02283741 0,03586349 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,02283741 0,03584806 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,02283741 0,03583264 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,02283741 0,03581723 ! protein complex scaffold GO:0032947 22 18 0,000 0,02283741 0,03580184 ! SNAP receptor activity GO:0005484 21 18 0,000 0,02283741 0,03578646 ! dendrite development GO:0016358 22 18 0,000 0,02283741 0,0357711 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,02283741 0,03575574 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,02283741 0,03574041 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,02283741 0,03572508 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,02283741 0,03570977 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,02283741 0,03569447 ! coreceptor activity GO:0015026 28 18 0,000 0,02283741 0,03567918 ! response to fungus GO:0009620 18 18 0,000 0,02283741 0,03566391 ! stem cell differentiation GO:0048863 18 18 0,000 0,02283741 0,03564865 ! intermediate filament-based process GO:0045103 18 18 0,000 0,02283741 0,0356334 ! heart process GO:0003015 19 18 0,000 0,02283741 0,03561816 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,02283741 0,03560294 ! vasodilation GO:0042311 20 18 0,000 0,02283741 0,03558773 ! transport vesicle membrane GO:0030658 23 18 0,000 0,02283741 0,03557254 ! MHC protein binding GO:0042287 30 18 0,000 0,02283741 0,03555736 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,02283741 0,03554219 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,02283741 0,03552703 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,02283741 0,03551189 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,02283741 0,03549676 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,02283741 0,03548164 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,02283741 0,03546653 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,02283741 0,03545144 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,02283741 0,03543636 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,02409139 0,03736624 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,02409139 0,03735036 ! proteasome core complex GO:0005839 20 19 0,000 0,02409139 0,03733449 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,02409139 0,03731864 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,02409139 0,0373028 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,02409139 0,03728697 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,02409139 0,03727116 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,02409139 0,03725536 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,02409139 0,03723958 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,02409139 0,0372238 ! lysosome organization GO:0007040 20 19 0,000 0,02409139 0,03720804 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,02409139 0,0371923 ! central nervous system neuron development GO:0021954 21 19 0,000 0,02409139 0,03717656 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,02409139 0,03716084 GO:0070003|threonine-type peptidase activity, ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,02409139 0,03714514 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,02409139 0,03712945 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,02409139 0,03711377 ! peptide cross-linking GO:0018149 23 19 0,000 0,02409139 0,0370981 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,02409139 0,03708245 ! beta-catenin binding GO:0008013 23 19 0,000 0,02409139 0,03706681 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,02409139 0,03705118 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,02409139 0,03703557 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02409139 0,03701997 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,02409139 0,03700438 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,02409139 0,0369888 ! vitamin transport GO:0051180 21 19 0,000 0,02409139 0,03697324 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,02409139 0,03695769 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,02409139 0,03694216 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,02409139 0,03692664 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,02409139 0,03691113 ! retinoid binding GO:0005501 19 19 0,000 0,02409139 0,03689563 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,02409139 0,03688015 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,02409139 0,03686468 ! histone deacetylase activity GO:0004407 20 19 0,000 0,02409139 0,03684922 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,02409139 0,03683378 ! gluconeogenesis GO:0006094 23 19 0,000 0,02409139 0,03681835 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,02409139 0,03680293 ! microtubule-based transport GO:0010970 20 19 0,000 0,02409139 0,03678753 ! superoxide metabolic process GO:0006801 21 19 0,000 0,02409139 0,03677213 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,02409139 0,03675675 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02409139 0,03674139 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,02409139 0,03672603 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,02409139 0,03671069 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,02409139 0,03669536 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,02409139 0,03668005 ! acetylcholine binding GO:0042166 20 19 0,000 0,02409139 0,03666475 ! heme metabolic process GO:0042168 20 19 0,000 0,02409139 0,03664946 ! SH2 domain binding GO:0042169 25 19 0,000 0,02409139 0,03663418 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,02409139 0,03661892 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,02409139 0,03660366 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,02409139 0,03658843 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,02409139 0,0365732 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,02409139 0,03655799 ! body fluid secretion GO:0007589 21 19 0,000 0,02409139 0,03654278 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,02409139 0,0365276 ! secretory granule membrane GO:0030667 21 19 0,000 0,02409139 0,03651242 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,02409139 0,03649726 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,02409139 0,03648211 ! peptidase activator activity GO:0016504 21 19 0,000 0,02409139 0,03646697 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02409139 0,03645184 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,02409139 0,03643673 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,02409139 0,03642163 ! sialyltransferase activity GO:0008373 31 19 0,000 0,02409139 0,03640654 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,02409139 0,03639147 ! chaperone binding GO:0051087 21 20 0,000 0,02534383 0,0382675 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,02534383 0,03825167 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,02534383 0,03823585 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,02534383 0,03822004 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,02534383 0,03820425 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,02534383 0,03818847 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,02534383 0,0381727 ! ovarian follicle development GO:0001541 21 20 0,000 0,02534383 0,03815695 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,02534383 0,03814121 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,02534383 0,03812548 ! diencephalon development GO:0021536 22 20 0,000 0,02534383 0,03810976 ! nuclear inner membrane GO:0005637 21 20 0,000 0,02534383 0,03809406 ! regulation of lipid transport GO:0032368 22 20 0,000 0,02534383 0,03807837 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,02534383 0,03806269 ! glutathione metabolic process GO:0006749 21 20 0,000 0,02534383 0,03804703 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,02534383 0,03803138 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,02534383 0,03801574 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,02534383 0,03800012 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,02534383 0,0379845 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,02534383 0,03796891 ! peptide hormone secretion GO:0030072 25 20 0,000 0,02534383 0,03795332 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,02534383 0,03793775 ! Rab GTPase binding GO:0017137 22 20 0,000 0,02534383 0,03792218 ! initiation of viral infection GO:0019059 22 20 0,000 0,02534383 0,03790664 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,02534383 0,0378911 ! heterochromatin GO:0000792 20 20 0,000 0,02534383 0,03787558 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,02534383 0,03786007 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,02534383 0,03784457 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,02534383 0,03782909 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,02534383 0,03781361 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,02534383 0,03779815 ! visual behavior GO:0007632 34 20 0,000 0,02534383 0,03778271 ! regulation of cell-matrix adhesion GO:0001952 26 20 0,000 0,02534383 0,03776727 GO:0010810|regulation of cell-substrate adhesion, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,02534383 0,03775185 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,02534383 0,03773644 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,02534383 0,03772105 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,02534383 0,03770566 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,02534383 0,03769029 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,02534383 0,03767493 ! rRNA binding GO:0019843 22 20 0,000 0,02534383 0,03765959 ! cytolysis GO:0019835 22 20 0,000 0,02534383 0,03764425 ! renal system process GO:0003014 22 20 0,000 0,02534383 0,03762893 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,02534383 0,03761362 ! fatty acid transport GO:0015908 23 20 0,000 0,02534383 0,03759833 ! transaminase activity GO:0008483 22 20 0,000 0,02534383 0,03758304 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,02534383 0,03756777 ! collagen catabolic process GO:0030574 21 20 0,000 0,02534383 0,03755251 ! microvillus GO:0005902 25 20 0,000 0,02534383 0,03753727 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,02534383 0,03752203 ! connexon complex GO:0005922 23 20 0,000 0,02534383 0,03750681 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,02659472 0,03934207 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,02659472 0,03932613 ! translational initiation GO:0006413 21 21 0,000 0,02659472 0,03931019 ! NF-kappaB binding GO:0051059 31 21 0,000 0,02659472 0,03929427 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,02659472 0,03927836 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,02659472 0,03926247 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,02659472 0,03924658 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,02659472 0,03923071 ! glutathione transferase activity GO:0004364 21 21 0,000 0,02659472 0,03921486 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,02659472 0,03919901 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,02659472 0,03918318 ! regeneration GO:0031099 24 21 0,000 0,02659472 0,03916736 ! apoptotic mitochondrial changes GO:0008637 33 21 0,000 0,02659472 0,03915155 ! MHC class I protein complex GO:0042612 31 21 0,000 0,02659472 0,03913576 ! cellular response to starvation GO:0009267 22 21 0,000 0,02659472 0,03911998 ! peroxisome organization GO:0007031 22 21 0,000 0,02659472 0,03910421 ! vacuole organization GO:0007033 23 21 0,000 0,02659472 0,03908846 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,02659472 0,03907272 ! neural crest cell development GO:0014032 24 21 0,000 0,02659472 0,03905699 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,02659472 0,03904127 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,02659472 0,03902556 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,02659472 0,03900987 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02659472 0,03899419 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,02659472 0,03897853 ! pallium development GO:0021543 22 21 0,000 0,02659472 0,03896287 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,02659472 0,03894723 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,02659472 0,0389316 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,02659472 0,03891599 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,02659472 0,03890038 ! cyclase activity GO:0009975 22 21 0,000 0,02659472 0,03888479 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,02659472 0,03886921 ! gut development GO:0048565 23 21 0,000 0,02659472 0,03885365 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,02659472 0,03883809 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,02659472 0,03882255 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02659472 0,03880702 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,02659472 0,0387915 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02659472 0,038776 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,02659472 0,03876051 ! axis specification GO:0009798 25 21 0,000 0,02659472 0,03874503 ! response to alkaloid GO:0043279 27 21 0,000 0,02659472 0,03872956 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,02659472 0,03871411 ! response to ethanol GO:0045471 28 21 0,000 0,02659472 0,03869866 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,02659472 0,03868323 ! smooth muscle contraction GO:0006939 25 21 0,000 0,02659472 0,03866782 ! vesicle targeting GO:0006903 22 21 0,000 0,02659472 0,03865241 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,02659472 0,03863702 ! SNARE binding GO:0000149 24 21 0,000 0,02659472 0,03862164 ! interaction with host GO:0051701 26 21 0,000 0,02659472 0,03860627 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,02659472 0,03859091 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,02659472 0,03857557 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,02659472 0,03856024 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,02659472 0,03854492 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,02659472 0,03852961 ! cell-cell junction organization GO:0045216 24 21 0,000 0,02659472 0,03851431 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,02659472 0,03849903 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,02659472 0,03848376 ! caveola GO:0005901 25 21 0,000 0,02659472 0,0384685 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,02659472 0,03845325 ! insulin receptor binding GO:0005158 25 21 0,000 0,02659472 0,03843802 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02659472 0,03842279 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02659472 0,03840758 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,02784408 0,04019597 ! metencephalon development GO:0022037 25 22 0,000 0,02784408 0,04018007 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,02784408 0,04016418 ! hormone secretion GO:0046879 28 22 0,000 0,02784408 0,0401483 ! vesicle docking GO:0048278 24 22 0,000 0,02784408 0,04013244 ! muscle myosin complex GO:0005859 23 22 0,000 0,02784408 0,04011659 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,02784408 0,04010075 ! actomyosin structure organization GO:0031032 24 22 0,000 0,02784408 0,04008493 ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,02784408 0,04006911 ! sperm motility GO:0030317 23 22 0,000 0,02784408 0,04005331 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,02784408 0,04003753 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,02784408 0,04002175 ! vacuolar transport GO:0007034 22 22 0,000 0,02784408 0,04000599 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,02784408 0,03999024 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,02784408 0,0399745 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,02784408 0,03995878 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,02784408 0,03994306 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,02784408 0,03992736 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,02784408 0,03991167 ! PML body GO:0016605 25 22 0,000 0,02784408 0,039896 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,02784408 0,03988033 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,02784408 0,03986468 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,02784408 0,03984904 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,02784408 0,03983341 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,02784408 0,0398178 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,02784408 0,0398022 ! deacetylase activity GO:0019213 23 22 0,000 0,02784408 0,03978661 ! pentose metabolic process GO:0019321 23 22 0,000 0,02784408 0,03977103 ! collagen fibril organization GO:0030199 32 22 0,000 0,02784408 0,03975546 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,02784408 0,03973991 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,02784408 0,03972437 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,02784408 0,03970884 ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,02784408 0,03969332 ! positive regulation of behavior GO:0048520 24 22 0,000 0,02784408 0,03967781 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,02784408 0,03966232 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,02784408 0,03964684 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,02784408 0,03963137 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,02784408 0,03961592 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,02784408 0,03960047 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,02784408 0,03958504 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,02784408 0,03956962 ! glycerol metabolic process GO:0006071 24 22 0,000 0,02784408 0,03955421 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,02784408 0,03953881 ! nuclear chromatin GO:0000790 23 22 0,000 0,02784408 0,03952343 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,02784408 0,03950805 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,02784408 0,03949269 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,02784408 0,03947734 ! sterol binding GO:0032934 24 22 0,000 0,02784408 0,03946201 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,02784408 0,03944668 ! digestive system process GO:0022600 25 22 0,000 0,02784408 0,03943137 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,02784408 0,03941607 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,02784408 0,03940078 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,02784408 0,0393855 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,02784408 0,03937023 ! base-excision repair GO:0006284 33 22 0,000 0,02784408 0,03935498 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,02784408 0,03933974 ! DNA modification GO:0006304 25 22 0,000 0,02784408 0,03932451 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,02784408 0,03930929 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,02784408 0,03929408 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,02784408 0,03927889 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,02784408 0,03926371 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,02784408 0,03924853 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,02784408 0,03923337 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,02784408 0,03921823 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,02784408 0,03920309 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,0290919 0,04094416 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,0290919 0,04092837 ! leukocyte adhesion GO:0007159 26 23 0,000 0,0290919 0,04091259 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,0290919 0,04089682 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,0290919 0,04088107 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,0290919 0,04086533 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,0290919 0,0408496 ! ureteric bud development GO:0001657 24 23 0,000 0,0290919 0,04083388 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,0290919 0,04081817 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,0290919 0,04080248 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,0290919 0,0407868 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,0290919 0,04077113 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,0290919 0,04075547 ! deaminase activity GO:0019239 24 23 0,000 0,0290919 0,04073983 ! sensory perception of pain GO:0019233 26 23 0,000 0,0290919 0,0407242 ! lipid kinase activity GO:0001727 26 23 0,000 0,0290919 0,04070857 ! platelet activation GO:0030168 27 23 0,000 0,0290919 0,04069297 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,0290919 0,04067737 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,0290919 0,04066178 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,0290919 0,04064621 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,0290919 0,04063065 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,0290919 0,0406151 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,0290919 0,04059956 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,0290919 0,04058404 ! cell surface binding GO:0043498 28 23 0,000 0,0290919 0,04056852 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,0290919 0,04055302 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,0290919 0,04053753 ! regulation of glucose import GO:0046324 28 23 0,000 0,0290919 0,04052205 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,0290919 0,04050659 ! alditol metabolic process GO:0019400 25 23 0,000 0,0290919 0,04049113 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,0290919 0,04047569 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,0290919 0,04046026 ! zinc ion transport GO:0006829 26 23 0,000 0,0290919 0,04044484 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,0290919 0,04042943 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,0290919 0,04041403 ! sex determination GO:0007530 25 23 0,000 0,0290919 0,04039865 ! phosphate binding GO:0042301 25 23 0,000 0,0290919 0,04038328 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,0290919 0,04036792 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,0290919 0,04035257 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,0290919 0,04033723 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,0290919 0,04032191 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,0290919 0,04030659 ! positive regulation of nuclear division GO:0051785 35 23 0,000 0,0290919 0,04029129 GO:0045840|positive regulation of mitosis, ! synaptogenesis GO:0007416 25 23 0,000 0,0290919 0,040276 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,0290919 0,04026072 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,0290919 0,04024545 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,0290919 0,04023019 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,0290919 0,04021495 ! leukocyte proliferation GO:0070661 26 23 0,000 0,0290919 0,04019972 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,0290919 0,0401845 ! growth cone GO:0030426 27 24 0,000 0,03033819 0,04189012 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,03033819 0,04187427 ! actin filament GO:0005884 26 24 0,000 0,03033819 0,04185844 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,03033819 0,04184261 ! pancreas development GO:0031016 27 24 0,000 0,03033819 0,0418268 ! calcium channel complex GO:0034704 31 24 0,000 0,03033819 0,04181099 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,03033819 0,0417952 ! negative regulation of cell development GO:0010721 30 24 0,000 0,03033819 0,04177943 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,03033819 0,04176366 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,03033819 0,04174791 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,03033819 0,04173217 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,03033819 0,04171644 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,03033819 0,04170072 ! Rho GTPase binding GO:0017048 36 24 0,000 0,03033819 0,04168501 ! regulation of glucose transport GO:0010827 29 24 0,000 0,03033819 0,04166932 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,03033819 0,04165363 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,03033819 0,04163796 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,03033819 0,0416223 ! protein stabilization GO:0050821 24 24 0,000 0,03033819 0,04160666 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,03033819 0,04159102 ! embryonic pattern specification GO:0009880 29 24 0,000 0,03033819 0,0415754 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,03033819 0,04155978 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,03033819 0,04154418 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,03033819 0,04152859 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,03033819 0,04151302 ! chemokine binding GO:0019956 26 24 0,000 0,03033819 0,04149745 ! catechol metabolic process GO:0009712 29 24 0,000 0,03033819 0,0414819 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,03033819 0,04146636 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,03033819 0,04145082 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,03033819 0,04143531 ! cell aging GO:0007569 47 24 0,000 0,03033819 0,0414198 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,03033819 0,0414043 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,03033819 0,04138882 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,03033819 0,04137335 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,03033819 0,04135789 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,03033819 0,04134244 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,03033819 0,041327 ! caspase regulator activity GO:0043028 26 24 0,000 0,03033819 0,04131157 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,03033819 0,04129616 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,03033819 0,04128075 ! selenium binding GO:0008430 24 24 0,000 0,03033819 0,04126536 ! spindle pole GO:0000922 35 24 0,000 0,03033819 0,04124998 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,03033819 0,04123461 ! site of polarized growth GO:0030427 28 25 0,000 0,03158294 0,04291045 ! phenol metabolic process GO:0018958 31 25 0,000 0,03158294 0,04289447 ! protein amino acid acylation GO:0043543 28 25 0,000 0,03158294 0,04287851 ! aromatase activity GO:0070330 28 25 0,000 0,03158294 0,04286256 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,03158294 0,04284662 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,03158294 0,04283069 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,03158294 0,04281477 ! response to starvation GO:0042594 26 25 0,000 0,03158294 0,04279887 ! dynein complex GO:0030286 28 25 0,000 0,03158294 0,04278298 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,03158294 0,0427671 ! regulation of behavior GO:0050795 27 25 0,000 0,03158294 0,04275123 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,03158294 0,04273537 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,03158294 0,04271952 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,03158294 0,04270369 ! hormone transport GO:0009914 31 25 0,000 0,03158294 0,04268787 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,03158294 0,04267206 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,03158294 0,04265626 ! regulation of coagulation GO:0050818 28 25 0,000 0,03158294 0,04264047 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03158294 0,0426247 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,03158294 0,04260893 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,03158294 0,04259318 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,03158294 0,04257744 ! molting cycle process GO:0022404 28 25 0,000 0,03158294 0,04256171 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,03158294 0,042546 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,03158294 0,04253029 ! phototransduction GO:0007602 27 25 0,000 0,03158294 0,0425146 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,03158294 0,04249891 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,03158294 0,04248324 ! protein phosphatase binding GO:0019903 27 25 0,000 0,03158294 0,04246758 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,03158294 0,04245194 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,03158294 0,0424363 ! autophagy GO:0006914 28 25 0,000 0,03158294 0,04242068 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,03158294 0,04240506 ! response to ionizing radiation GO:0010212 37 25 0,000 0,03158294 0,04238946 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,03158294 0,04237387 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,03282616 0,04402567 ! positive regulation of cell adhesion GO:0045785 34 26 0,000 0,03282616 0,04400949 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,03282616 0,04399332 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,03282616 0,04397717 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,03282616 0,04396102 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,03282616 0,04394489 ! hair cycle GO:0042633 29 26 0,000 0,03282616 0,04392877 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,03282616 0,04391266 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,03282616 0,04389656 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,03282616 0,04388048 ! early endosome membrane GO:0031901 31 26 0,000 0,03282616 0,04386441 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,03282616 0,04384834 ! iron ion homeostasis GO:0055072 29 26 0,000 0,03282616 0,04383229 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,03282616 0,04381626 ! GABA receptor activity GO:0016917 31 26 0,000 0,03282616 0,04380023 ! PDZ domain binding GO:0030165 28 26 0,000 0,03282616 0,04378421 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,03282616 0,04376821 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,03282616 0,04375222 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,03282616 0,04373624 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,03282616 0,04372027 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,03282616 0,04370432 ! fatty acid binding GO:0005504 28 26 0,000 0,03282616 0,04368837 ! blastocyst development GO:0001824 27 26 0,000 0,03282616 0,04367244 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,03282616 0,04365652 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,03282616 0,04364061 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,03282616 0,04362471 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,03282616 0,04360882 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,03282616 0,04359295 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,03282616 0,04357708 ! iron ion transport GO:0006826 33 26 0,000 0,03282616 0,04356123 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,03282616 0,04354539 ! glucose transport GO:0015758 27 26 0,000 0,03282616 0,04352956 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,03282616 0,04351375 ! spinal cord development GO:0021510 30 26 0,000 0,03282616 0,04349794 ! histone deacetylase complex GO:0000118 29 26 0,000 0,03282616 0,04348214 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,03282616 0,04346636 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,03282616 0,04345059 ! RNA helicase activity GO:0003724 46 26 0,000 0,03282616 0,04343483 ! brush border GO:0005903 30 26 0,000 0,03282616 0,04341908 ! gap junction GO:0005921 29 26 0,000 0,03282616 0,04340334 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,03282616 0,04338762 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,03406785 0,0450125 ! RNA export from nucleus GO:0006405 31 27 0,000 0,03406785 0,0449962 ! mRNA catabolic process GO:0006402 31 27 0,000 0,03406785 0,04497992 ! myelination GO:0042552 31 27 0,000 0,03406785 0,04496365 ! trans-Golgi network GO:0005802 31 27 0,000 0,03406785 0,04494738 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,03406785 0,04493113 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,03406785 0,0449149 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,03406785 0,04489867 ! vasculogenesis GO:0001570 32 27 0,000 0,03406785 0,04488245 ! hexose transport GO:0008645 28 27 0,000 0,03406785 0,04486625 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,03406785 0,04485006 ! spindle organization GO:0007051 38 27 0,000 0,03406785 0,04483388 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,03406785 0,04481771 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,03406785 0,04480156 ! cell fate determination GO:0001709 29 27 0,000 0,03406785 0,04478541 ! lipid oxidation GO:0034440 29 27 0,000 0,03406785 0,04476928 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,03406785 0,04475316 ! collagen binding GO:0005518 29 27 0,000 0,03406785 0,04473705 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,03406785 0,04472095 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,03406785 0,04470486 ! liver development GO:0001889 33 27 0,000 0,03406785 0,04468879 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,03406785 0,04467272 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,03406785 0,04465667 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,03406785 0,04464063 ! membrane docking GO:0022406 29 27 0,000 0,03406785 0,0446246 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,03406785 0,04460858 GO:0050908|detection of light stimulus involved in visual perception, ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,03406785 0,04459258 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,03406785 0,04457658 ! phospholipid transport GO:0015914 29 27 0,000 0,03406785 0,0445606 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,03406785 0,04454463 ! aminopeptidase activity GO:0004177 33 27 0,000 0,03406785 0,04452867 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,03406785 0,04451272 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,03406785 0,04449678 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,03406785 0,04448086 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,03406785 0,04446494 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,03406785 0,04444904 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,03530801 0,04605064 ! Golgi stack GO:0005795 30 28 0,000 0,03530801 0,04603418 ! male gonad development GO:0008584 32 28 0,000 0,03530801 0,04601773 ! lipoprotein binding GO:0008034 31 28 0,000 0,03530801 0,0460013 ! mesoderm formation GO:0001707 34 28 0,000 0,03530801 0,04598487 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,03530801 0,04596846 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,03530801 0,04595206 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,03530801 0,04593567 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,03530801 0,0459193 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,03530801 0,04590293 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,03530801 0,04588658 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,03530801 0,04587024 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,03530801 0,04585391 ! tissue homeostasis GO:0001894 31 28 0,000 0,03530801 0,04583759 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,03530801 0,04582128 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,03530801 0,04580499 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,03530801 0,04578871 ! sister chromatid segregation GO:0000819 49 28 0,000 0,03530801 0,04577243 ! post-embryonic development GO:0009791 32 28 0,000 0,03530801 0,04575617 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,03530801 0,04573993 ! detection of visible light GO:0009584 30 28 0,000 0,03530801 0,04572369 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,03530801 0,04570746 ! receptor regulator activity GO:0030545 31 28 0,000 0,03530801 0,04569125 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,03530801 0,04567505 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,03530801 0,04565886 ! response to heat GO:0009408 33 28 0,000 0,03530801 0,04564268 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,03530801 0,04562651 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,03654665 0,0472104 ! hormone binding GO:0042562 31 29 0,000 0,03654665 0,04719369 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,03654665 0,04717699 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,03654665 0,0471603 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,03654665 0,04714363 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,03654665 0,04712696 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,03654665 0,04711031 ! erythrocyte differentiation GO:0030218 35 29 0,000 0,03654665 0,04709367 ! ceramide metabolic process GO:0006672 29 29 0,000 0,03654665 0,04707704 ! replication fork GO:0005657 42 29 0,000 0,03654665 0,04706042 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,03654665 0,04704382 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,03654665 0,04702722 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,03654665 0,04701064 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,03654665 0,04699407 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,03654665 0,04697751 ! regulation of pH GO:0006885 30 29 0,000 0,03654665 0,04696097 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,03654665 0,04694443 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,03654665 0,04692791 ! phospholipase C activity GO:0004629 43 29 0,000 0,03654665 0,04691139 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,03654665 0,04689489 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,03654665 0,0468784 ! sodium channel activity GO:0005272 33 29 0,000 0,03654665 0,04686193 ! sarcoplasm GO:0016528 31 29 0,000 0,03654665 0,04684546 ! detection of light stimulus GO:0009583 31 29 0,000 0,03654665 0,04682901 ! spermatid development GO:0007286 30 29 0,000 0,03654665 0,04681256 ! DNA polymerase activity GO:0034061 34 29 0,000 0,03654665 0,04679613 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,03654665 0,04677971 ! sarcolemma GO:0042383 30 29 0,000 0,03654665 0,0467633 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,03654665 0,04674691 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,03654665 0,04673052 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,03654665 0,04671415 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,03778376 0,04827852 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,03778376 0,04826161 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,03778376 0,04824472 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,03778376 0,04822784 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,03778376 0,04821097 ! scavenger receptor activity GO:0005044 39 30 0,000 0,03778376 0,04819411 ! spliceosome assembly GO:0000245 34 30 0,000 0,03778376 0,04817727 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,03778376 0,04816044 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,03778376 0,04814361 ! metanephros development GO:0001656 31 30 0,000 0,03778376 0,0481268 ! glutamate receptor activity GO:0008066 35 30 0,000 0,03778376 0,04811001 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,03778376 0,04809322 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,03778376 0,04807645 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,03778376 0,04805968 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,03778376 0,04804293 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,03778376 0,04802619 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,03778376 0,04800946 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,03778376 0,04799275 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,03778376 0,04797604 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,03778376 0,04795935 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,03778376 0,04794267 ! protein-lipid complex GO:0032994 41 30 0,000 0,03778376 0,047926 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,03778376 0,04790934 ! negative regulation of protein modification process GO:0031400 34 30 0,000 0,03778376 0,04789269 ! phosphatase binding GO:0019902 34 30 0,000 0,03778376 0,04787606 ! acute-phase response GO:0006953 44 30 0,000 0,03778376 0,04785943 ! segmentation GO:0035282 37 30 0,000 0,03778376 0,04784282 ! response to toxin GO:0009636 33 30 0,000 0,03778376 0,04782622 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,03778376 0,04780963 ! antigen binding GO:0003823 33 30 0,000 0,03778376 0,04779305 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,03778376 0,04777649 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,03778376 0,04775993 ! ensheathment of neurons GO:0007272 35 30 0,000 0,03778376 0,04774339 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,03778376 0,04772686 ! vesicle localization GO:0051648 31 30 0,000 0,03778376 0,04771034 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,03901935 0,0492535 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03901935 0,04923646 ! acrosomal vesicle GO:0001669 34 31 0,000 0,03901935 0,04921943 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03901935 0,04920242 ! protein targeting to membrane GO:0006612 35 31 0,000 0,03901935 0,04918542 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,03901935 0,04916843 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,03901935 0,04915145 ! formation of primary germ layer GO:0001704 37 31 0,000 0,03901935 0,04913449 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,03901935 0,04911753 ! endocytic vesicle GO:0030139 33 31 0,000 0,03901935 0,04910059 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,03901935 0,04908366 ! spermatid differentiation GO:0048515 32 31 0,000 0,03901935 0,04906674 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,03901935 0,04904983 ! neuron fate commitment GO:0048663 44 31 0,000 0,03901935 0,04903293 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,03901935 0,04901605 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,03901935 0,04899917 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,03901935 0,04898231 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,03901935 0,04896546 ! cell junction assembly GO:0034329 36 31 0,000 0,03901935 0,04894863 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,03901935 0,0489318 ! peptide transport GO:0015833 36 31 0,000 0,03901935 0,04891498 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,03901935 0,04889818 ! peripheral nervous system development GO:0007422 35 31 0,000 0,03901935 0,04888139 ! I band GO:0031674 34 31 0,000 0,03901935 0,04886461 ! BMP signaling pathway GO:0030509 33 31 0,000 0,03901935 0,04884784 ! adult locomotory behavior GO:0008344 37 31 0,000 0,03901935 0,04883108 ! gene silencing GO:0016458 33 31 0,000 0,03901935 0,04881434 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,04025342 0,05034093 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,04025342 0,05032368 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,04025342 0,05030644 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,04025342 0,05028921 ! meiosis I GO:0007127 53 32 0,000 0,04025342 0,05027199 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,04025342 0,05025479 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,04025342 0,0502376 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,04025342 0,05022041 ! vesicle coat GO:0030120 39 32 0,000 0,04025342 0,05020324 ! cytokine production GO:0001816 32 32 0,000 0,04025342 0,05018609 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,04025342 0,05016894 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,04025342 0,05015181 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,04025342 0,05013468 ! oxygen binding GO:0019825 33 32 0,000 0,04025342 0,05011757 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,04025342 0,05010047 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,04025342 0,05008339 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,04025342 0,05006631 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,04025342 0,05004925 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,04148598 0,05156417 ! DNA helicase activity GO:0003678 55 33 0,000 0,04148598 0,05154661 ! neural tube development GO:0021915 37 33 0,000 0,04148598 0,05152906 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,04148598 0,05151152 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,04148598 0,05149399 ! organelle envelope lumen GO:0031970 46 33 0,000 0,04148598 0,05147648 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,04148598 0,05145897 ! NAD or NADH binding GO:0051287 36 33 0,000 0,04148598 0,05144148 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,04148598 0,051424 ! B cell differentiation GO:0030183 37 33 0,000 0,04148598 0,05140653 ! aerobic respiration GO:0009060 35 33 0,000 0,04148598 0,05138908 ! embryonic organ development GO:0048568 41 33 0,000 0,04148598 0,05137164 ! placenta development GO:0001890 39 33 0,000 0,04148598 0,0513542 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,04148598 0,05133678 ! tissue remodeling GO:0048771 37 33 0,000 0,04148598 0,05131938 ! flagellum GO:0019861 34 33 0,000 0,04148598 0,05130198 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,04148598 0,05128459 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,04148598 0,05126722 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,04148598 0,05124986 ! odontogenesis GO:0042476 39 34 0,000 0,04271701 0,05275276 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,04271701 0,05273491 ! lipid homeostasis GO:0055088 37 34 0,000 0,04271701 0,05271707 ! telencephalon development GO:0021537 36 34 0,000 0,04271701 0,05269924 ! negative regulation of hydrolase activity GO:0051346 36 34 0,000 0,04271701 0,05268142 ! clathrin coat GO:0030118 41 34 0,000 0,04271701 0,05266362 ! cell growth GO:0016049 36 34 0,000 0,04271701 0,05264583 ! protein polymerization GO:0051258 38 34 0,000 0,04271701 0,05262805 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,04271701 0,05261028 ! learning GO:0007612 51 34 0,000 0,04271701 0,05259252 ! keratinization GO:0031424 40 34 0,000 0,04271701 0,05257478 ! ovulation cycle process GO:0022602 35 34 0,000 0,04271701 0,05255705 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,04271701 0,05253933 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,04271701 0,05252162 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,04271701 0,05250393 ! amino acid binding GO:0016597 40 34 0,000 0,04271701 0,05248624 ! regulation of protein stability GO:0031647 35 34 0,000 0,04271701 0,05246857 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,04271701 0,05245091 ! glycogen metabolic process GO:0005977 48 34 0,000 0,04271701 0,05243326 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,04271701 0,05241562 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,04271701 0,052398 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,04271701 0,05238039 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,04394653 0,05386994 GO:0090047|positive regulation of transcription regulator activity, ! inner ear morphogenesis GO:0042472 46 35 0,000 0,04394653 0,05385184 ! MHC protein complex GO:0042611 50 35 0,000 0,04394653 0,05383376 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,04394653 0,05381569 ! vesicle lumen GO:0031983 38 35 0,000 0,04394653 0,05379763 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,04394653 0,05377958 ! mesenchymal cell development GO:0014031 40 35 0,000 0,04394653 0,05376155 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,04394653 0,05374353 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,04394653 0,05372551 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,04394653 0,05370752 ! regulation of proteolysis GO:0030162 37 35 0,000 0,04394653 0,05368953 ! ovulation cycle GO:0042698 37 35 0,000 0,04394653 0,05367156 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,04394653 0,05365359 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,04394653 0,05363564 ! collagen GO:0005581 54 35 0,000 0,04394653 0,0536177 ! glucan metabolic process GO:0044042 49 35 0,000 0,04394653 0,05359978 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,04394653 0,05358186 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,04394653 0,05356396 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,04394653 0,05354607 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,04394653 0,05352819 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,04394653 0,05351033 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,04394653 0,05349247 ! maintenance of protein location GO:0045185 45 35 0,000 0,04394653 0,05347463 ! polyol metabolic process GO:0019751 46 35 0,000 0,04394653 0,0534568 ! cytokinesis GO:0000910 38 35 0,000 0,04394653 0,05343898 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,04394653 0,05342117 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,04517453 0,05489564 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,04517453 0,05487736 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,04517453 0,05485909 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,04517453 0,05484083 ! SMAD binding GO:0046332 39 36 0,000 0,04517453 0,05482259 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,04517453 0,05480436 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,04517453 0,05478614 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,04517453 0,05476793 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,04517453 0,05474973 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,04517453 0,05473155 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,04517453 0,05471338 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,04517453 0,05469522 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,04517453 0,05467707 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,04517453 0,05465894 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,04517453 0,05464082 ! maintenance of location in cell GO:0051651 38 36 0,000 0,04517453 0,0546227 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,04640103 0,05608713 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,04640103 0,05606855 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,04640103 0,05604998 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,04640103 0,05603143 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,04640103 0,05601289 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,04640103 0,05599436 ! endoribonuclease activity GO:0004521 48 37 0,000 0,04640103 0,05597584 ! hindbrain development GO:0030902 43 37 0,000 0,04640103 0,05595734 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,04640103 0,05593885 ! pigmentation GO:0043473 51 37 0,000 0,04640103 0,05592037 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,04640103 0,0559019 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,04640103 0,05588344 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,04640103 0,055865 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,04640103 0,05584657 ! sensory perception of taste GO:0050909 37 37 0,000 0,04640103 0,05582815 ! cell junction organization GO:0034330 44 37 0,000 0,04640103 0,05580974 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,04640103 0,05579135 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,04640103 0,05577297 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,04640103 0,05575459 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,04640103 0,05573624 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,04640103 0,05571789 ! coated pit GO:0005905 44 37 0,000 0,04640103 0,05569956 ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,04762601 0,05715121 ! regulation of translational initiation GO:0006446 50 38 0,000 0,04762601 0,05713242 ! negative regulation of binding GO:0051100 44 38 0,000 0,04762601 0,05711364 ! organic ether metabolic process GO:0018904 50 38 0,000 0,04762601 0,05709487 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,04762601 0,05707611 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,04762601 0,05705737 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,04762601 0,05703864 ! synapse organization GO:0050808 43 38 0,000 0,04762601 0,05701992 ! viral infectious cycle GO:0019058 40 38 0,000 0,04762601 0,05700121 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,04762601 0,05698252 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,04762601 0,05696383 ! organic anion transport GO:0015711 42 38 0,000 0,04762601 0,05694516 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,04762601 0,0569265 ! monosaccharide binding GO:0048029 41 38 0,000 0,04762601 0,05690786 ! muscle fiber development GO:0048747 42 38 0,000 0,04762601 0,05688922 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,04762601 0,0568706 ! phagocytosis GO:0006909 44 38 0,000 0,04762601 0,05685199 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,04762601 0,0568334 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,04762601 0,05681481 ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,04762601 0,05679624 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,04762601 0,05677768 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,04762601 0,05675913 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,04884949 0,05819821 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,04884949 0,05817921 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,04884949 0,05816023 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,04884949 0,05814125 ! T cell differentiation GO:0030217 64 39 0,000 0,04884949 0,05812229 ! cell fate specification GO:0001708 55 39 0,000 0,04884949 0,05810334 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,04884949 0,0580844 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,04884949 0,05806547 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,04884949 0,05804656 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,04884949 0,05802766 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,04884949 0,05800877 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,04884949 0,05798989 ! amine receptor activity GO:0008227 48 39 0,000 0,04884949 0,05797103 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,04884949 0,05795217 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,04884949 0,05793333 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,04884949 0,0579145 ! pigment metabolic process GO:0042440 43 39 0,000 0,04884949 0,05789569 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,05007146 0,05932468 ! peroxisomal membrane GO:0005778 44 40 0,000 0,05007146 0,05930541 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,05007146 0,05928617 ! positive regulation of cell development GO:0010720 43 40 0,000 0,05007146 0,05926693 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,05007146 0,05924771 ! biopolymer methylation GO:0043414 45 40 0,000 0,05007146 0,05922849 ! neuron migration GO:0001764 43 40 0,000 0,05007146 0,0592093 ! regulation of protein secretion GO:0050708 45 40 0,000 0,05007146 0,05919011 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,05007146 0,05917093 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,05007146 0,05915177 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,05007146 0,05913262 ! positive regulation of defense response GO:0031349 41 40 0,000 0,05007146 0,05911349 ! mammary gland development GO:0030879 47 40 0,000 0,05007146 0,05909436 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,05007146 0,05907525 ! neuropeptide binding GO:0042923 42 40 0,000 0,05007146 0,05905615 ! regulation of tube size GO:0035150 44 40 0,000 0,05007146 0,05903706 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,05007146 0,05901799 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,05007146 0,05899893 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,05007146 0,05897988 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,05007146 0,05896084 ! chromatin remodeling GO:0006338 44 40 0,000 0,05007146 0,05894181 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,05007146 0,0589228 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,05129192 0,06033955 ! Notch signaling pathway GO:0007219 46 41 0,000 0,05129192 0,06032009 ! keratin filament GO:0045095 44 41 0,000 0,05129192 0,06030065 ! peptide metabolic process GO:0006518 42 41 0,000 0,05129192 0,06028123 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,05129192 0,06026181 ! late endosome membrane GO:0031902 45 41 0,000 0,05129192 0,06024241 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,05129192 0,06022302 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,05129192 0,06020365 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,05129192 0,06018428 ! lamellipodium GO:0030027 56 41 0,000 0,05129192 0,06016493 ! glycolysis GO:0006096 43 41 0,000 0,05129192 0,06014559 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,05129192 0,06012626 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,05129192 0,06010695 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,05129192 0,06008765 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,05251088 0,06149589 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,05251088 0,06147616 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,05251088 0,06145643 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,05251088 0,06143672 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,05251088 0,06141703 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,05251088 0,06139734 ! nuclear export GO:0051168 46 42 0,000 0,05251088 0,06137767 ! developmental growth GO:0048589 45 42 0,000 0,05251088 0,06135801 ! structural constituent of muscle GO:0008307 46 42 0,000 0,05251088 0,06133836 ! mitochondrial transport GO:0006839 45 42 0,000 0,05251088 0,06131873 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,05251088 0,06129911 ! metal cluster binding GO:0051540 47 42 0,000 0,05251088 0,0612795 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,05251088 0,0612599 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,05251088 0,06124032 ! RNA catabolic process GO:0006401 49 43 0,000 0,05372835 0,06264014 ! ear morphogenesis GO:0042471 56 43 0,000 0,05372835 0,06262013 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,05372835 0,06260013 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,05372835 0,06258014 ! positive regulation of growth GO:0045927 47 43 0,000 0,05372835 0,06256017 ! cell recognition GO:0008037 51 43 0,000 0,05372835 0,06254021 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,05372835 0,06252026 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,05372835 0,06250032 ! gliogenesis GO:0042063 46 43 0,000 0,05372835 0,0624804 ! endosome transport GO:0016197 48 43 0,000 0,05372835 0,06246049 ! striated muscle contraction GO:0006941 45 43 0,000 0,05372835 0,06244059 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,05372835 0,0624207 ! antioxidant activity GO:0016209 53 43 0,000 0,05372835 0,06240083 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,05372835 0,06238097 ! activation of caspase activity GO:0006919 60 43 0,000 0,05372835 0,06236112 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,05372835 0,06234129 ! histone modification GO:0016570 45 43 0,000 0,05372835 0,06232146 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,05372835 0,06230165 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,05494431 0,0636914 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,05494431 0,06367117 ! negative regulation of cell migration GO:0030336 53 44 0,000 0,05494431 0,06365095 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,05494431 0,06363074 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,05494431 0,06361055 ! chemokine activity GO:0008009 48 44 0,000 0,05494431 0,06359037 ! ruffle GO:0001726 50 44 0,000 0,05494431 0,0635702 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,05494431 0,06355004 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,05494431 0,0635299 ! cartilage development GO:0051216 48 44 0,000 0,05494431 0,06350977 ! membrane fusion GO:0006944 52 44 0,000 0,05494431 0,06348965 ! channel regulator activity GO:0016247 54 44 0,000 0,05494431 0,06346955 ! excretion GO:0007588 53 44 0,000 0,05494431 0,06344946 ! male sex differentiation GO:0046661 52 44 0,000 0,05494431 0,06342938 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,05494431 0,06340931 ! amino acid activation GO:0043038 45 44 0,000 0,05494431 0,06338926 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,05494431 0,06336922 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,05615877 0,06474943 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,05615877 0,06472897 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,05615877 0,06470853 ! organellar ribosome GO:0000313 46 45 0,000 0,05615877 0,0646881 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,05615877 0,06466768 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,05615877 0,06464727 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,05615877 0,06462688 ! transport vesicle GO:0030133 53 45 0,000 0,05615877 0,0646065 ! regulation of endocytosis GO:0030100 52 45 0,000 0,05615877 0,06458613 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,05615877 0,06456577 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,05615877 0,06454543 ! nuclear matrix GO:0016363 56 45 0,000 0,05615877 0,0645251 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,05615877 0,06450479 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,05615877 0,06448448 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,05615877 0,06446419 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,05615877 0,06444391 ! coated vesicle membrane GO:0030662 52 45 0,000 0,05615877 0,06442365 ! covalent chromatin modification GO:0016569 47 45 0,000 0,05615877 0,06440339 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,05615877 0,06438315 ! synaptosome GO:0019717 50 45 0,000 0,05615877 0,06436293 ! chemokine receptor binding GO:0042379 50 45 0,000 0,05615877 0,06434271 ! regulation of action potential GO:0001508 56 46 0,000 0,05737174 0,06571181 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,05737174 0,06569118 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,05737174 0,06567057 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,05737174 0,06564997 ! eye morphogenesis GO:0048592 57 46 0,000 0,05737174 0,06562938 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,05737174 0,06560881 ! methylation GO:0032259 51 46 0,000 0,05737174 0,06558825 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,05737174 0,0655677 ! regulation of ion transport GO:0043269 54 46 0,000 0,05737174 0,06554717 ! leukocyte migration GO:0050900 49 46 0,000 0,05737174 0,06552665 ! neuromuscular process GO:0050905 56 46 0,000 0,05737174 0,06550614 ! sulfotransferase activity GO:0008146 54 46 0,000 0,05737174 0,06548564 ! JNK cascade GO:0007254 48 46 0,000 0,05737174 0,06546516 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,05737174 0,06544469 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,05858321 0,06680574 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,05858321 0,06678487 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,05858321 0,066764 ! microtubule binding GO:0008017 61 47 0,000 0,05858321 0,06674315 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,05858321 0,06672231 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,05858321 0,06670149 ! viral reproductive process GO:0022415 53 47 0,000 0,05858321 0,06668068 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,05858321 0,06665988 ! response to insulin stimulus GO:0032868 57 47 0,000 0,05858321 0,06663909 ! axon GO:0030424 53 48 0,000 0,0597932 0,06799426 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,0597932 0,06797307 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,0597932 0,0679519 ! proteasome complex GO:0000502 50 48 0,000 0,0597932 0,06793073 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,0597932 0,06790958 ! protein homooligomerization GO:0051260 63 48 0,000 0,0597932 0,06788845 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,0597932 0,06786733 ! kinetochore GO:0000776 69 48 0,000 0,0597932 0,06784622 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,0597932 0,06782512 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,0597932 0,06780404 ! growth factor receptor binding GO:0070851 58 48 0,000 0,0597932 0,06778297 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,0597932 0,06776191 ! inner ear development GO:0048839 60 48 0,000 0,0597932 0,06774086 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,0597932 0,06771983 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,0597932 0,06769882 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,0597932 0,06767781 ! B cell mediated immunity GO:0019724 53 48 0,000 0,0597932 0,06765682 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,0597932 0,06763584 ! regulation of cell shape GO:0008360 55 48 0,000 0,0597932 0,06761487 ! establishment of organelle localization GO:0051656 58 48 0,000 0,0597932 0,06759392 ! cell cortex part GO:0044448 54 48 0,000 0,0597932 0,06757298 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,06100169 0,06891736 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,06100169 0,06889603 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,06100169 0,0688747 ! response to temperature stimulus GO:0009266 57 49 0,000 0,06100169 0,06885339 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,06100169 0,0688321 ! lipid modification GO:0030258 55 49 0,000 0,06100169 0,06881081 ! synaptic vesicle GO:0008021 56 49 0,000 0,06100169 0,06878954 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,06100169 0,06876828 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,06100169 0,06874704 ! maintenance of location GO:0051235 62 49 0,000 0,06100169 0,06872581 ! negative regulation of cell motion GO:0051271 60 49 0,000 0,06100169 0,06870459 ! regulation of actin filament length GO:0030832 62 49 0,000 0,06100169 0,06868338 ! nuclear periphery GO:0034399 60 49 0,000 0,06100169 0,06866219 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,06100169 0,06864101 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,06220869 0,06997759 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,06220869 0,06995601 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,06220869 0,06993446 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,06220869 0,06991291 ! glucose catabolic process GO:0006007 54 50 0,000 0,06220869 0,06989138 ! aging GO:0007568 92 50 0,000 0,06220869 0,06986986 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,06220869 0,06984836 ! heart morphogenesis GO:0003007 57 50 0,000 0,06220869 0,06982687 ! integrin binding GO:0005178 56 50 0,000 0,06220869 0,06980539 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,06220869 0,06978392 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,06341421 0,07111437 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,06341421 0,07109251 ! regulation of ossification GO:0030278 59 51 0,000 0,06341421 0,07107067 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,06341421 0,07104884 ! positive regulation of organelle organization GO:0010638 69 51 0,000 0,06341421 0,07102703 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,06341421 0,07100523 ! endocrine system development GO:0035270 55 51 0,000 0,06341421 0,07098344 ! germ cell development GO:0007281 56 51 0,000 0,06341421 0,07096167 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,06461824 0,07228683 ! regulation of cellular component size GO:0032535 66 52 0,000 0,06461824 0,07226467 ! carbohydrate transport GO:0008643 57 52 0,000 0,06461824 0,07224252 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,06461824 0,07222039 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,06461824 0,07219827 ! cell maturation GO:0048469 68 52 0,000 0,06461824 0,07217616 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,06461824 0,07215407 ! vesicle organization GO:0016050 59 52 0,000 0,06461824 0,07213199 ! kidney development GO:0001822 55 52 0,000 0,06461824 0,07210992 ! cellular component disassembly GO:0022411 69 52 0,000 0,06461824 0,07208787 ! cell redox homeostasis GO:0045454 57 52 0,000 0,06461824 0,07206583 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,06461824 0,07204381 ! lipid transporter activity GO:0005319 58 52 0,000 0,06461824 0,0720218 ! cytokine receptor activity GO:0004896 54 52 0,000 0,06461824 0,0719998 ! antiporter activity GO:0015297 53 52 0,000 0,06461824 0,07197781 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,06582079 0,07329494 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,06582079 0,07327258 ! keratinocyte differentiation GO:0030216 60 53 0,000 0,06582079 0,07325022 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,06582079 0,07322789 ! basement membrane GO:0005604 55 53 0,000 0,06582079 0,07320556 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,06582079 0,07318325 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,06582079 0,07316095 ! viral reproduction GO:0016032 59 53 0,000 0,06582079 0,07313866 ! chloride transport GO:0006821 60 53 0,000 0,06582079 0,07311639 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,06582079 0,07309414 ! regulation of protein catabolic process GO:0042176 56 53 0,000 0,06582079 0,07307189 ! regulation of DNA replication GO:0006275 75 53 0,000 0,06582079 0,07304966 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,06582079 0,07302744 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,06582079 0,07300524 ! single fertilization GO:0007338 58 53 0,000 0,06582079 0,07298305 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,06702185 0,07429223 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,06702185 0,07426966 ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,06702185 0,07424711 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,06702185 0,07422457 ! coated membrane GO:0048475 65 54 0,000 0,06702185 0,07420204 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,06702185 0,07417953 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,06702185 0,07415703 ! cellular defense response GO:0006968 61 54 0,000 0,06702185 0,07413454 ! gastrulation GO:0007369 62 54 0,000 0,06702185 0,07411207 ! dendrite GO:0030425 60 55 0,000 0,06822144 0,0754157 ! regulation of mitosis GO:0007088 79 55 0,000 0,06822144 0,07539286 GO:0051783|regulation of nuclear division, ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,06822144 0,07537002 ! respiratory chain GO:0070469 57 55 0,000 0,06822144 0,0753472 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,06822144 0,0753244 ! extracellular matrix organization GO:0030198 77 55 0,000 0,06822144 0,07530161 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,06822144 0,07527883 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,06822144 0,07525607 ! translation initiation factor activity GO:0003743 66 55 0,000 0,06822144 0,07523332 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,06941955 0,07653143 ! heat shock protein binding GO:0031072 62 56 0,000 0,06941955 0,07650831 ! late endosome GO:0005770 60 56 0,000 0,06941955 0,0764852 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,06941955 0,07646211 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,06941955 0,07643903 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,06941955 0,07641597 ! ribonuclease activity GO:0004540 67 56 0,000 0,06941955 0,07639291 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,06941955 0,07636988 ! mesoderm development GO:0007498 67 56 0,000 0,06941955 0,07634685 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,06941955 0,07632384 ! antigen processing and presentation GO:0019882 73 56 0,000 0,06941955 0,07630085 ! proton transport GO:0015992 59 56 0,000 0,06941955 0,07627787 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,07061618 0,07756935 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,07061618 0,077546 ! diacylglycerol binding GO:0019992 65 57 0,000 0,07061618 0,07752267 ! B cell activation GO:0042113 63 57 0,000 0,07061618 0,07749935 ! small ribosomal subunit GO:0015935 58 57 0,000 0,07061618 0,07747604 ! detection of external stimulus GO:0009581 64 57 0,000 0,07061618 0,07745274 ! occluding junction GO:0070160 75 58 0,000 0,07181134 0,07873993 GO:0005923|tight junction, ! epidermal cell differentiation GO:0009913 66 58 0,000 0,07181134 0,07871627 ! hydrogen transport GO:0006818 61 58 0,000 0,07181134 0,07869263 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,07181134 0,078669 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,07181134 0,07864538 ! response to nutrient GO:0007584 68 58 0,000 0,07181134 0,07862178 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,07181134 0,07859819 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,07181134 0,07857461 ! myosin complex GO:0016459 64 58 0,000 0,07181134 0,07855105 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,07300502 0,07983283 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,07300502 0,0798089 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,07300502 0,079785 ! actin filament organization GO:0007015 65 59 0,000 0,07300502 0,0797611 ! regulation of heart contraction GO:0008016 71 59 0,000 0,07300502 0,07973722 ! hexose catabolic process GO:0019320 64 59 0,000 0,07300502 0,07971335 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,07300502 0,0796895 ! cell projection assembly GO:0030031 79 59 0,000 0,07300502 0,07966566 ! appendage morphogenesis GO:0035107 68 59 0,000 0,07300502 0,07964184 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,07300502 0,07961803 ! fertilization GO:0009566 65 59 0,000 0,07300502 0,07959424 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,07300502 0,07957046 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,07300502 0,07954669 ! adult behavior GO:0030534 72 59 0,000 0,07300502 0,07952294 ! organelle localization GO:0051640 70 59 0,000 0,07300502 0,0794992 ! positive regulation of secretion GO:0051047 66 60 0,000 0,07419723 0,08077335 ! molecular adaptor activity GO:0060090 73 60 0,000 0,07419723 0,08074926 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,07419723 0,08072517 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,07419723 0,08070111 ! copper ion binding GO:0005507 85 60 0,000 0,07419723 0,08067705 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,07419723 0,08065301 ! activation of immune response GO:0002253 72 60 0,000 0,07419723 0,08062899 ! cell cycle checkpoint GO:0000075 91 60 0,000 0,07419723 0,08060498 ! regulation of caspase activity GO:0043281 78 60 0,000 0,07419723 0,08058098 ! appendage development GO:0048736 69 60 0,000 0,07419723 0,080557 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,07419723 0,08053303 ! secondary metabolic process GO:0019748 67 60 0,000 0,07419723 0,08050907 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,07538798 0,08177679 ! ear development GO:0043583 76 61 0,000 0,07538798 0,08175248 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,07538798 0,08172818 ! learning or memory GO:0007611 79 61 0,000 0,07538798 0,0817039 ! Ras GTPase binding GO:0017016 78 61 0,000 0,07538798 0,08167964 ! camera-type eye development GO:0043010 69 61 0,000 0,07538798 0,08165539 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,07657725 0,08291891 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,07657725 0,08289431 ! lysosomal membrane GO:0005765 69 62 0,000 0,07657725 0,08286972 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,07657725 0,08284514 ! nuclear pore GO:0005643 79 62 0,000 0,07657725 0,08282058 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,07657725 0,08279603 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,07657725 0,0827715 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,07657725 0,08274698 ! chloride channel activity GO:0005254 72 62 0,000 0,07657725 0,08272248 ! cell soma GO:0043025 68 62 0,000 0,07657725 0,08269799 ! microtubule motor activity GO:0003777 94 62 0,000 0,07657725 0,08267352 ! focal adhesion GO:0005925 72 62 0,000 0,07657725 0,08264906 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,07657725 0,08262461 ! FAD binding GO:0050660 71 63 0,000 0,07776506 0,08388141 ! regulation of endopeptidase activity GO:0052548 81 63 0,000 0,07776506 0,08385662 ! urogenital system development GO:0001655 75 63 0,000 0,07776506 0,08383184 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,07776506 0,08380707 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,07776506 0,08378232 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,07776506 0,08375759 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,07776506 0,08373286 ! regulation of immune effector process GO:0002697 81 63 0,000 0,07776506 0,08370816 ! respiratory tube development GO:0030323 92 64 0,000 0,07895141 0,0849601 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,07895141 0,08493504 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,07895141 0,08491 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,07895141 0,08488498 ! adaptive immune response GO:0002250 70 64 0,000 0,07895141 0,08485997 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,07895141 0,08483497 ! neurotransmitter transport GO:0006836 72 64 0,000 0,07895141 0,08480999 ! regulation of actin cytoskeleton organization GO:0032956 93 64 0,000 0,07895141 0,08478502 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,07895141 0,08476007 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,08013629 0,08600682 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,08013629 0,08598152 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,08013629 0,08595624 ! activation of MAPK activity GO:0000187 74 65 0,000 0,08013629 0,08593098 ! gonad development GO:0008406 71 65 0,000 0,08013629 0,08590572 ! acetyltransferase activity GO:0016407 73 65 0,000 0,08013629 0,08588049 ! protein import into nucleus GO:0006606 73 66 0,000 0,08131971 0,08712314 ! developmental maturation GO:0021700 85 66 0,000 0,08131971 0,08709756 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,08131971 0,087072 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,08131971 0,08704645 ! tube morphogenesis GO:0035239 84 66 0,000 0,08131971 0,08702092 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,08131971 0,0869954 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,08131971 0,08696989 ! regulation of peptidase activity GO:0052547 86 67 0,000 0,08250167 0,08820812 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,08250167 0,08818227 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,08250167 0,08815644 ! nuclear import GO:0051170 74 67 0,000 0,08250167 0,08813063 ! response to peptide hormone stimulus GO:0043434 79 67 0,000 0,08250167 0,08810483 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,08250167 0,08807905 ! regulation of actin filament-based process GO:0032970 96 67 0,000 0,08250167 0,08805328 ! chloride ion binding GO:0031404 79 67 0,000 0,08250167 0,08802752 ! humoral immune response GO:0006959 75 67 0,000 0,08250167 0,08800178 ! amine binding GO:0043176 77 67 0,000 0,08250167 0,08797606 ! female pregnancy GO:0007565 78 67 0,000 0,08250167 0,08795035 ! extrinsic to membrane GO:0019898 75 67 0,000 0,08250167 0,08792466 ! anion channel activity GO:0005253 77 67 0,000 0,08250167 0,08789898 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,08250167 0,08787331 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,08368218 0,08910467 ! amine catabolic process GO:0009310 73 68 0,000 0,08368218 0,08907866 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,08368218 0,08905268 ! cell-substrate junction GO:0030055 78 68 0,000 0,08368218 0,08902671 ! respiratory system development GO:0060541 96 68 0,000 0,08368218 0,08900075 ! mRNA transport GO:0051028 88 69 0,000 0,08486123 0,09022843 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,08486123 0,09020214 ! small GTPase binding GO:0031267 86 69 0,000 0,08486123 0,09017587 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,08486123 0,09014961 ! sarcomere GO:0030017 74 69 0,000 0,08486123 0,09012336 ! exocytosis GO:0006887 76 69 0,000 0,08486123 0,09009713 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,08486123 0,09007092 GO:0060538|skeletal muscle organ development, ! nucleosome assembly GO:0006334 87 69 0,000 0,08486123 0,09004472 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,08486123 0,09001854 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,08486123 0,08999237 ! amine biosynthetic process GO:0009309 78 70 0,000 0,08603882 0,09121465 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,08603882 0,09118815 ! early endosome GO:0005769 104 70 0,000 0,08603882 0,09116167 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,08603882 0,0911352 ! regulation of lipase activity GO:0060191 78 70 0,000 0,08603882 0,09110874 ! amino acid transport GO:0006865 76 70 0,000 0,08603882 0,0910823 ! chromatin assembly GO:0031497 88 70 0,000 0,08603882 0,09105588 ! calcium channel activity GO:0005262 86 70 0,000 0,08603882 0,09102947 ! axon guidance GO:0007411 87 70 0,000 0,08603882 0,09100308 ! cell cortex GO:0005938 77 70 0,000 0,08603882 0,0909767 ! nuclear chromosome part GO:0044454 94 70 0,000 0,08603882 0,09095034 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,08721497 0,09216692 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,08721497 0,09214022 ! protein localization in nucleus GO:0034504 78 71 0,000 0,08721497 0,09211355 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,08721497 0,09208689 ! pore complex GO:0046930 89 72 0,000 0,08838966 0,09330019 ! response to hypoxia GO:0001666 84 72 0,000 0,08838966 0,09327321 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,08838966 0,09324623 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,08838966 0,09321927 ! regulation of lyase activity GO:0051339 85 72 0,000 0,08838966 0,09319233 ! acute inflammatory response GO:0002526 91 72 0,000 0,08838966 0,09316541 ! apical junction complex GO:0043296 90 72 0,000 0,08838966 0,0931385 ! phospholipase activity GO:0004620 99 72 0,000 0,08838966 0,0931116 ! membrane raft GO:0045121 81 72 0,000 0,08838966 0,09308472 ! regulation of neurological system process GO:0031644 91 72 0,000 0,08838966 0,09305786 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,08838966 0,09303101 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,0895629 0,09423867 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,0895629 0,09421149 ! protein transporter activity GO:0008565 80 73 0,000 0,0895629 0,09418434 ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,0895629 0,09415719 ! exopeptidase activity GO:0008238 81 73 0,000 0,0895629 0,09413007 ! digestion GO:0007586 81 73 0,000 0,0895629 0,09410296 ! regulation of Rho protein signal transduction GO:0035023 88 73 0,000 0,0895629 0,09407586 ! cell-matrix adhesion GO:0007160 102 74 0,000 0,0907347 0,09527927 ! response to oxygen levels GO:0070482 86 74 0,000 0,0907347 0,09525185 ! potassium channel complex GO:0034705 84 74 0,000 0,0907347 0,09522445 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,0907347 0,09519706 ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,0907347 0,09516969 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,0907347 0,09514233 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,0907347 0,09511499 ! blood coagulation GO:0007596 90 74 0,000 0,0907347 0,09508767 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,0907347 0,09506036 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,0907347 0,09503307 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,0907347 0,09500579 ! cell projection part GO:0044463 80 74 0,000 0,0907347 0,09497853 ! meiosis GO:0007126 108 75 0,000 0,09190505 0,09617602 GO:0051327|M phase of meiotic cell cycle, ! regulation of DNA binding GO:0051101 94 75 0,000 0,09190505 0,09614844 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,09190505 0,09612088 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,09190505 0,09609333 ! regulation of blood pressure GO:0008217 82 75 0,000 0,09190505 0,09606579 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,09190505 0,09603828 ! neuropeptide signaling pathway GO:0007218 85 76 0,000 0,09307396 0,0972319 ! defense response to bacterium GO:0042742 81 76 0,000 0,09307396 0,09720406 ! cell leading edge GO:0031252 97 76 0,000 0,09307396 0,09717624 ! meiotic cell cycle GO:0051321 109 76 0,000 0,09307396 0,09714844 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,09307396 0,09712065 ! protein-DNA complex GO:0032993 93 76 0,000 0,09307396 0,09709288 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,09307396 0,09706512 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,09307396 0,09703738 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,09307396 0,09700966 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,09424142 0,09819843 ! nucleosome organization GO:0034728 96 77 0,000 0,09424142 0,09817039 ! alcohol catabolic process GO:0046164 84 77 0,000 0,09424142 0,09814237 ! vacuolar membrane GO:0005774 86 77 0,000 0,09424142 0,09811436 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,09424142 0,09808636 ! regulation of Ras GTPase activity GO:0032318 88 77 0,000 0,09424142 0,09805839 ! establishment of RNA localization GO:0051236 97 77 0,000 0,09424142 0,09803043 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! myofibril GO:0030016 82 77 0,000 0,09424142 0,09800248 ! protein oligomerization GO:0051259 93 77 0,000 0,09424142 0,09797455 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,09540745 0,09915851 ! endonuclease activity GO:0004519 111 78 0,000 0,09540745 0,09913027 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,09540745 0,09910204 ! inorganic anion transport GO:0015698 87 78 0,000 0,09540745 0,09907383 ! regulation of protein transport GO:0051223 85 78 0,000 0,09540745 0,09904564 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,09540745 0,09901746 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,09540745 0,0989893 ! carboxylesterase activity GO:0004091 93 78 0,000 0,09540745 0,09896115 ! protein ubiquitination GO:0016567 95 78 0,000 0,09540745 0,09893302 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,09540745 0,09890491 ! contractile fiber part GO:0044449 83 78 0,000 0,09540745 0,09887681 ! RNA localization GO:0006403 99 79 0,000 0,09657203 0,10005532 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,09657203 0,10002691 ! vitamin metabolic process GO:0006766 86 79 0,000 0,09657203 0,09999852 ! T cell activation GO:0042110 120 79 0,000 0,09657203 0,09997014 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,09657203 0,09994178 ! phosphoinositide binding GO:0035091 99 79 0,000 0,09657203 0,09991344 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,09773518 0,10108816 ! eye development GO:0001654 93 80 0,000 0,09773518 0,10105951 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,09773518 0,10103087 ! rhythmic process GO:0048511 90 80 0,000 0,09773518 0,10100225 ! regulation of catabolic process GO:0009894 87 80 0,000 0,09773518 0,10097365 ! SH3 domain binding GO:0017124 95 80 0,000 0,09773518 0,10094506 ! hemostasis GO:0007599 96 80 0,000 0,09773518 0,10091649 ! chromosome, centromeric region GO:0000775 119 80 0,000 0,09773518 0,10088793 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,09773518 0,10085939 ! cell-substrate adhesion GO:0031589 109 80 0,000 0,09773518 0,10083087 ! rRNA processing GO:0006364 84 80 0,000 0,09773518 0,10080236 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,0988969 0,1019717 ! vacuolar part GO:0044437 91 81 0,000 0,0988969 0,10194289 ! ossification GO:0001503 111 82 0,000 0,10005718 0,10310977 ! mitochondrion organization GO:0007005 104 82 0,000 0,10005718 0,10308065 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,10005718 0,10305155 ! forebrain development GO:0030900 93 82 0,000 0,10005718 0,10302246 ! external side of plasma membrane GO:0009897 105 82 0,000 0,10005718 0,10299339 ! cellular respiration GO:0045333 85 82 0,000 0,10005718 0,10296434 ! heparin binding GO:0008201 108 82 0,000 0,10005718 0,1029353 ! microtubule-based movement GO:0007018 119 83 0,000 0,10121603 0,10409813 ! nuclear speck GO:0016607 99 83 0,000 0,10121603 0,10406879 ! rRNA metabolic process GO:0016072 88 83 0,000 0,10121603 0,10403947 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,10121603 0,10401016 GO:0070035|purine NTP-dependent helicase activity, ! regulation of cell adhesion GO:0030155 98 83 0,000 0,10121603 0,10398087 ! regulation of T cell activation GO:0050863 104 83 0,000 0,10121603 0,1039516 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,10121603 0,10392234 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,10121603 0,1038931 ! contractile fiber GO:0043292 88 83 0,000 0,10121603 0,10386387 ! bone development GO:0060348 112 83 0,000 0,10121603 0,10383466 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,10121603 0,10380547 ! regulation of membrane potential GO:0042391 98 83 0,000 0,10121603 0,1037763 ! cilium GO:0005929 88 83 0,000 0,10121603 0,10374714 ! regulation of defense response GO:0031347 98 84 0,000 0,10237345 0,10490403 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,10237345 0,10487457 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,10237345 0,10484512 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,10352944 0,10599927 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,10352944 0,10596952 ! monooxygenase activity GO:0004497 92 85 0,000 0,10352944 0,1059398 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,10352944 0,10591009 ! protein binding, bridging GO:0030674 104 85 0,000 0,10352944 0,1058804 ! negative regulation of transport GO:0051051 98 86 0,000 0,104684 0,10703118 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,104684 0,10700119 ! Golgi vesicle transport GO:0048193 98 86 0,000 0,104684 0,10697121 ! lipase activity GO:0016298 114 86 0,000 0,104684 0,10694126 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,104684 0,10691132 ! adherens junction GO:0005912 100 86 0,000 0,104684 0,1068814 ! leukocyte differentiation GO:0002521 118 87 0,000 0,10583714 0,10802851 ! pigment granule GO:0048770 101 87 0,000 0,10583714 0,10799829 GO:0042470|melanosome, ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,10583714 0,10796809 ! organelle outer membrane GO:0031968 102 88 0,000 0,10698885 0,10911248 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,10698885 0,10908198 ! growth factor binding GO:0019838 102 88 0,000 0,10698885 0,10905151 ! protein processing GO:0016485 100 88 0,000 0,10698885 0,10902104 ! gland development GO:0048732 108 89 0,000 0,10813915 0,11016242 ! ATP metabolic process GO:0046034 100 90 0,000 0,10928802 0,1113017 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,10928802 0,11127064 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,10928802 0,11123959 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,10928802 0,11120856 ! sterol metabolic process GO:0016125 102 90 0,000 0,10928802 0,11117755 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,10928802 0,11114656 ! anion binding GO:0043168 104 90 0,000 0,10928802 0,11111558 ! amine transport GO:0015837 97 90 0,000 0,10928802 0,11108462 ! response to virus GO:0009615 109 90 0,000 0,10928802 0,11105368 ! outer membrane GO:0019867 104 90 0,000 0,10928802 0,11102275 ! extracellular matrix part GO:0044420 111 90 0,000 0,10928802 0,11099184 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,11043548 0,11212597 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,11043548 0,11209477 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,11043548 0,11206359 ! sulfur metabolic process GO:0006790 98 91 0,000 0,11043548 0,11203243 ! sex differentiation GO:0007548 103 91 0,000 0,11043548 0,11200128 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 0,000 0,11043548 0,11197015 ! hormone metabolic process GO:0042445 107 91 0,000 0,11043548 0,11193904 ! regulation of protein localization GO:0032880 99 91 0,000 0,11043548 0,11190795 ! detection of stimulus GO:0051606 100 91 0,000 0,11043548 0,11187687 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,11158151 0,11300649 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,11158151 0,11297512 ! regulation of cellular component biogenesis GO:0044087 115 92 0,000 0,11158151 0,11294377 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,11158151 0,11291244 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,11158151 0,11288113 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,11158151 0,11284984 ! regulation of GTPase activity GO:0043087 105 92 0,000 0,11158151 0,11281856 ! extracellular structure organization GO:0043062 119 92 0,000 0,11158151 0,1127873 ! protein import GO:0017038 102 93 0,000 0,11272614 0,11391273 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,11272614 0,11388118 ! response to nutrient levels GO:0031667 105 93 0,000 0,11272614 0,11384965 ! Ras protein signal transduction GO:0007265 118 93 0,000 0,11272614 0,11381814 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,11272614 0,11378665 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,11386935 0,11490882 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,11386935 0,11487704 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,11386935 0,11484528 GO:0060429|epithelium development, ! anchoring junction GO:0070161 108 94 0,000 0,11386935 0,11481354 ! neurotransmitter binding GO:0042165 105 94 0,000 0,11386935 0,11478181 ! homophilic cell adhesion GO:0007156 107 95 0,000 0,11501115 0,11590073 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,11501115 0,11586873 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,11501115 0,11583674 ! protein localization in organelle GO:0033365 104 95 0,000 0,11501115 0,11580476 ! Wnt receptor signaling pathway GO:0016055 121 95 0,000 0,11501115 0,11577281 ! immune effector process GO:0002252 110 95 0,000 0,11501115 0,11574087 ! apical plasma membrane GO:0016324 105 95 0,000 0,11501115 0,11570895 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,11615153 0,11682404 ! in utero embryonic development GO:0001701 110 96 0,000 0,11615153 0,11679184 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,11615153 0,11675966 ! receptor complex GO:0043235 131 96 0,000 0,11615153 0,11672749 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,11615153 0,11669534 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,11615153 0,11666321 ! electron transport chain GO:0022900 104 97 0,000 0,11729051 0,11777479 ! microtubule associated complex GO:0005875 135 97 0,000 0,11729051 0,11774238 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,11729051 0,11770998 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,11729051 0,11767761 ! carboxylic acid binding GO:0031406 108 97 0,000 0,11729051 0,11764526 ! protein maturation GO:0051604 109 97 0,000 0,11729051 0,11761292 ! intermediate filament GO:0005882 102 98 0,000 0,11842809 0,11872098 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,11842809 0,11868837 ! cell fate commitment GO:0045165 118 98 0,000 0,11842809 0,11865577 ! hormone activity GO:0005179 113 99 0,000 0,11956426 0,11976123 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,11956426 0,11972836 ! unfolded protein binding GO:0051082 118 100 0,000 0,12069902 0,12083151 ! nuclear chromosome GO:0000228 127 100 0,000 0,12069902 0,12079836 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,12069902 0,12076523 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 0,000 0,12069902 0,12073212 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,12069902 0,12069902