pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/6134-7-real-Parker_GPL1390-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL1390.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 51 50 4,000 4,62E-10 1,65E-06 ! interphase of mitotic cell cycle GO:0051329 84 82 4,000 5,864E-09 1,047E-05 GO:0051325|interphase, ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 2,997E-08 3,568E-05 ! G1/S transition of mitotic cell cycle GO:0000082 47 46 3,000 5,823E-08 5,199E-05 ! cyclin-dependent protein kinase regulator activity GO:0016538 11 11 2,000 8,818E-08 6,298E-05 ! G2/M transition of mitotic cell cycle GO:0000086 17 17 2,000 3,623E-07 2,156E-04 ! microtubule organizing center part GO:0044450 34 31 2,000 2,378E-06 1,213E-03 ! DNA-directed RNA polymerase activity GO:0003899 35 34 2,000 3,161E-06 1,411E-03 GO:0034062|RNA polymerase activity, ! response to calcium ion GO:0051592 39 35 2,000 3,455E-06 1,371E-03 ! induction of apoptosis by intracellular signals GO:0008629 46 43 2,000 6,488E-06 2,317E-03 ! regulation of retroviral genome replication GO:0045091 5 5 1,000 7,176E-06 2,329E-03 ! DNA topoisomerase activity GO:0003916 5 5 1,000 7,176E-06 2,135E-03 ! RNA elongation from RNA polymerase II promoter GO:0006368 48 46 2,000 7,969E-06 2,189E-03 ! RNA elongation GO:0006354 51 49 2,000 9,657E-06 2,463E-03 ! response to UV GO:0009411 50 49 2,000 9,657E-06 2,299E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 1,076E-05 2,401E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 9 6 1,000 1,076E-05 2,26E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! positive regulation of protein ubiquitination GO:0031398 6 6 1,000 1,076E-05 2,134E-03 ! DNA topological change GO:0006265 6 6 1,000 1,076E-05 2,022E-03 ! DNA catabolic process GO:0006308 55 54 2,000 1,297E-05 2,315E-03 ! positive regulation of viral reproduction GO:0048524 7 7 1,000 1,505E-05 2,56E-03 ! postreplication repair GO:0006301 7 7 1,000 1,505E-05 2,444E-03 ! transcription from RNA polymerase I promoter GO:0006360 7 7 1,000 1,505E-05 2,337E-03 ! chromosome segregation GO:0007059 59 57 2,000 1,527E-05 2,273E-03 ! negative regulation of lipid biosynthetic process GO:0051055 9 8 1,000 2,006E-05 2,866E-03 ! regulation of DNA repair GO:0006282 8 8 1,000 2,006E-05 2,755E-03 ! DNA ligation GO:0006266 8 8 1,000 2,006E-05 2,653E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 8 8 1,000 2,006E-05 2,559E-03 ! protein kinase regulator activity GO:0019887 64 64 2,000 2,167E-05 2,669E-03 ! response to metal ion GO:0010038 69 65 2,000 2,271E-05 2,703E-03 ! positive regulation of protein modification process GO:0031401 69 65 2,000 2,271E-05 2,616E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 71 67 2,000 2,488E-05 2,777E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 9 9 1,000 2,578E-05 2,79E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 9 9 1,000 2,578E-05 2,708E-03 ! response to inorganic substance GO:0010035 74 70 2,000 2,839E-05 2,896E-03 ! adult heart development GO:0007512 12 10 1,000 3,221E-05 3,195E-03 ! gamma-tubulin complex GO:0000930 12 10 1,000 3,221E-05 3,109E-03 ! kinase regulator activity GO:0019207 77 77 2,000 3,78E-05 3,552E-03 ! pseudouridine synthase activity GO:0009982 12 11 1,000 3,935E-05 3,603E-03 ! histone deacetylase binding GO:0042826 11 11 1,000 3,935E-05 3,513E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 3,935E-05 3,427E-03 ! protein kinase binding GO:0019901 89 80 2,000 4,239E-05 3,604E-03 ! transcription initiation GO:0006352 86 82 2,000 4,565E-05 3,791E-03 ! centriole GO:0005814 12 12 1,000 4,719E-05 3,83E-03 ! negative regulation of lipid metabolic process GO:0045833 13 12 1,000 4,719E-05 3,745E-03 ! protein kinase C binding GO:0005080 13 12 1,000 4,719E-05 3,664E-03 ! cell cycle arrest GO:0007050 92 87 2,000 5,449E-05 4,14E-03 ! pseudouridine synthesis GO:0001522 14 13 1,000 5,575E-05 4,147E-03 ! regulation of protein ubiquitination GO:0031396 13 13 1,000 5,575E-05 4,063E-03 ! double-strand break repair via homologous recombination GO:0000724 13 13 1,000 5,575E-05 3,982E-03 GO:0000725|recombinational repair, ! nucleolar part GO:0044452 13 13 1,000 5,575E-05 3,903E-03 ! centrosome cycle GO:0007098 14 14 1,000 6,501E-05 4,464E-03 ! protein serine/threonine kinase inhibitor activity GO:0030291 14 14 1,000 6,501E-05 4,38E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 6,501E-05 4,299E-03 ! nucleotidyltransferase activity GO:0016779 96 94 2,000 6,867E-05 4,458E-03 ! regulation of viral genome replication GO:0045069 15 15 1,000 7,497E-05 4,781E-03 ! ubiquitin binding GO:0043130 15 15 1,000 7,497E-05 4,697E-03 ! kinase binding GO:0019900 108 99 2,000 8,014E-05 4,934E-03 ! regulation of lipid biosynthetic process GO:0046890 18 17 1,000 9,701E-05 5,871E-03 ! nuclear ubiquitin ligase complex GO:0000152 17 17 1,000 9,701E-05 5,774E-03 ! regulation of viral reproduction GO:0050792 18 18 1,000 1,091E-04 6,386E-03 ! negative regulation of cell cycle process GO:0010948 18 18 1,000 1,091E-04 6,283E-03 ! small conjugating protein binding GO:0032182 18 18 1,000 1,091E-04 6,183E-03 ! cellular response to unfolded protein GO:0034620 21 19 1,000 1,219E-04 6,799E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! microtubule organizing center organization GO:0031023 20 20 1,000 1,353E-04 7,434E-03 GO:0051297|centrosome organization, ! chromosome condensation GO:0030261 20 20 1,000 1,353E-04 7,322E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 21 20 1,000 1,353E-04 7,213E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 24 21 1,000 1,495E-04 7,851E-03 ! regulation of fatty acid metabolic process GO:0019217 22 21 1,000 1,495E-04 7,737E-03 ! DNA-directed RNA polymerase complex GO:0000428 22 21 1,000 1,495E-04 7,626E-03 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! intramolecular transferase activity GO:0016866 22 21 1,000 1,495E-04 7,519E-03 ! positive regulation of fibroblast proliferation GO:0048146 22 21 1,000 1,495E-04 7,414E-03 ! positive regulation of B cell activation GO:0050871 26 22 1,000 1,644E-04 8,04E-03 ! RNA polymerase complex GO:0030880 23 22 1,000 1,644E-04 7,932E-03 ! negative regulation of phosphorylation GO:0042326 26 22 1,000 1,644E-04 7,826E-03 ! androgen receptor binding GO:0050681 23 23 1,000 1,799E-04 8,454E-03 ! apoptotic nuclear changes GO:0030262 23 23 1,000 1,799E-04 8,344E-03 ! negative regulation of phosphorus metabolic process GO:0010563 27 23 1,000 1,799E-04 8,237E-03 GO:0045936|negative regulation of phosphate metabolic process, ! nucleotide-excision repair, DNA damage removal GO:0000718 24 23 1,000 1,799E-04 8,133E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 24 24 1,000 1,962E-04 8,757E-03 ! regulation of fibroblast proliferation GO:0048145 25 24 1,000 1,962E-04 8,649E-03 ! regulation of cellular ketone metabolic process GO:0010565 26 25 1,000 2,131E-04 9,282E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 27 25 1,000 2,131E-04 9,17E-03 ! fat cell differentiation GO:0045444 26 26 1,000 2,308E-04 9,811E-03 ! response to endoplasmic reticulum stress GO:0034976 29 26 1,000 2,308E-04 9,696E-03 ! cellular response to extracellular stimulus GO:0031668 27 26 1,000 2,308E-04 9,583E-03 ! deoxyribonuclease activity GO:0004536 28 28 1,000 2,682E-04 0,01100661 ! ER-nuclear signaling pathway GO:0006984 31 28 1,000 2,682E-04 0,01088154 ! protein kinase inhibitor activity GO:0004860 28 28 1,000 2,682E-04 0,01075927 ! kinase inhibitor activity GO:0019210 30 30 1,000 3,083E-04 0,01223195 ! drug binding GO:0008144 30 30 1,000 3,083E-04 0,01209753 ! regulation of microtubule-based process GO:0032886 32 30 1,000 3,083E-04 0,01196604 ! regulation of Wnt receptor signaling pathway GO:0030111 35 32 1,000 3,512E-04 0,01348389 ! regulation of B cell activation GO:0050864 36 32 1,000 3,512E-04 0,01334045 ! steroid hormone receptor binding GO:0035258 33 33 1,000 3,736E-04 0,01404464 ! androgen receptor signaling pathway GO:0030521 34 33 1,000 3,736E-04 0,01389834 ! positive regulation of DNA metabolic process GO:0051054 40 35 1,000 4,206E-04 0,01548507 ! positive regulation of leukocyte proliferation GO:0070665 40 36 1,000 4,451E-04 0,01622058 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! DNA-dependent ATPase activity GO:0008094 39 37 1,000 4,703E-04 0,01696582 ! multicellular organismal metabolic process GO:0044236 38 37 1,000 4,703E-04 0,01679616 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 40 38 1,000 4,962E-04 0,01754501 ! RNA modification GO:0009451 39 38 1,000 4,962E-04 0,017373 ! positive regulation of cell cycle GO:0045787 39 39 1,000 5,228E-04 0,01812527 ! response to estrogen stimulus GO:0043627 41 40 1,000 5,5E-04 0,01888637 ! regulation of gene expression, epigenetic GO:0040029 43 40 1,000 5,5E-04 0,0187065 ! protein serine/threonine phosphatase activity GO:0004722 42 40 1,000 5,5E-04 0,01853003 ! nucleus organization GO:0006997 40 40 1,000 5,5E-04 0,01835685 ! hydro-lyase activity GO:0016836 44 41 1,000 5,78E-04 0,01911003 ! double-strand break repair GO:0006302 41 41 1,000 5,78E-04 0,0189347 ! damaged DNA binding GO:0003684 42 42 1,000 6,066E-04 0,0196909 ! regulation of mast cell proliferation GO:0070666 48 44 1,000 6,658E-04 0,02141859 ! regulation of leukocyte proliferation GO:0070663 50 46 1,000 7,277E-04 0,02320133 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! protein N-terminus binding GO:0047485 51 48 1,000 7,923E-04 0,02503738 ! carbon-oxygen lyase activity GO:0016835 54 51 1,000 8,942E-04 0,02801014 ! DNA damage response, signal transduction GO:0042770 58 52 1,000 9,295E-04 0,02886287 ! positive regulation of protein amino acid phosphorylation GO:0001934 54 52 1,000 9,295E-04 0,02861405 ! negative regulation of cytoskeleton organization GO:0051494 57 52 1,000 9,295E-04 0,02836948 ! tRNA processing GO:0008033 55 54 1,000 1,002E-03 0,03032628 ! regulation of cellular response to stress GO:0080135 57 54 1,000 1,002E-03 0,03007144 ! nucleotide-excision repair GO:0006289 58 55 1,000 1,039E-03 0,03093076 ! positive regulation of phosphorylation GO:0042327 59 57 1,000 1,116E-03 0,03293523 ! steroid hormone receptor signaling pathway GO:0030518 58 57 1,000 1,116E-03 0,03266527 ! positive regulation of phosphorus metabolic process GO:0010562 61 58 1,000 1,155E-03 0,03354014 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of lipid metabolic process GO:0019216 63 60 1,000 1,236E-03 0,03558906 ! negative regulation of protein kinase activity GO:0006469 67 61 1,000 1,277E-03 0,03648295 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 62 61 1,000 1,277E-03 0,0361934 ! cell cycle checkpoint GO:0000075 64 61 1,000 1,277E-03 0,03590841 ! negative regulation of kinase activity GO:0033673 68 62 1,000 1,319E-03 0,03679716 ! intracellular receptor-mediated signaling pathway GO:0030522 64 63 1,000 1,362E-03 0,03769027 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 66 64 1,000 1,405E-03 0,0385876 ! negative regulation of cell growth GO:0030308 68 65 1,000 1,449E-03 0,03948904 ! negative regulation of transferase activity GO:0051348 71 65 1,000 1,449E-03 0,03918988 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 67 65 1,000 1,449E-03 0,03889522 ! response to steroid hormone stimulus GO:0048545 69 66 1,000 1,493E-03 0,03979156 ! response to unfolded protein GO:0006986 68 66 1,000 1,493E-03 0,03949681 ! negative regulation of cell size GO:0045792 70 67 1,000 1,538E-03 0,04039264 ! tubulin binding GO:0015631 70 67 1,000 1,538E-03 0,0400978 ! positive regulation of lymphocyte activation GO:0051251 72 67 1,000 1,538E-03 0,03980724 ! nuclear hormone receptor binding GO:0035257 68 67 1,000 1,538E-03 0,03952085 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 69 67 1,000 1,538E-03 0,03923856 ! ubiquitin ligase complex GO:0000151 71 67 1,000 1,538E-03 0,03896027 ! positive regulation of ligase activity GO:0051351 71 69 1,000 1,631E-03 0,04100718 ! regulation of ubiquitin-protein ligase activity GO:0051438 74 72 1,000 1,774E-03 0,0442993 ! response to protein stimulus GO:0051789 74 72 1,000 1,774E-03 0,04399167 ! negative regulation of organelle organization GO:0010639 78 73 1,000 1,823E-03 0,04489659 ! hormone receptor binding GO:0051427 75 73 1,000 1,823E-03 0,04458908 ! positive regulation of cell activation GO:0050867 80 75 1,000 1,923E-03 0,04671642 GO:0002696|positive regulation of leukocyte activation, ! phosphoinositide-mediated signaling GO:0048015 79 75 1,000 1,923E-03 0,04640077 ! regulation of ligase activity GO:0051340 78 76 1,000 1,974E-03 0,04731147 ! endonuclease activity GO:0004519 80 77 1,000 2,026E-03 0,04822529 ! regulation of DNA metabolic process GO:0051052 90 80 1,000 2,184E-03 0,05165993 ! regulation of cell cycle process GO:0010564 84 80 1,000 2,184E-03 0,05132006 ! negative regulation of growth GO:0045926 84 80 1,000 2,184E-03 0,05098463 ! condensed chromosome GO:0000793 82 80 1,000 2,184E-03 0,05065357 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 85 84 1,000 2,405E-03 0,05540835 GO:0010498|proteasomal protein catabolic process, ! DNA recombination GO:0006310 86 85 1,000 2,462E-03 0,05635171 ! microtubule cytoskeleton organization GO:0000226 92 87 1,000 2,577E-03 0,05861645 ! protein tyrosine phosphatase activity GO:0004725 104 92 1,000 2,876E-03 0,065012 ! DNA packaging GO:0006323 94 92 1,000 2,876E-03 0,06460312 ! regulation of lymphocyte activation GO:0051249 100 95 1,000 3,064E-03 0,06837619 ! chromatin binding GO:0003682 102 99 1,000 3,322E-03 0,07367919 ! protein C-terminus binding GO:0008022 106 99 1,000 3,322E-03 0,07322438 ! tRNA metabolic process GO:0006399 101 100 1,000 3,388E-03 0,07422344 ! tRNA transcription GO:0009304 5 5 0,000 4,404E-03 0,09590278 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 5 5 0,000 4,404E-03 0,09532155 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 4,404E-03 0,09474732 ! benzene and derivative metabolic process GO:0042537 5 5 0,000 4,404E-03 0,09417997 ! response to oxygen radical GO:0000305 5 5 0,000 4,404E-03 0,09361938 ! positive regulation of axon extension GO:0045773 6 5 0,000 4,404E-03 0,09306542 ! negative regulation of bone resorption GO:0045779 5 5 0,000 4,404E-03 0,09251797 ! positive regulation of lipid biosynthetic process GO:0046889 5 5 0,000 4,404E-03 0,09197693 ! regulation of interferon-beta production GO:0032648 6 5 0,000 4,404E-03 0,09144218 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! sodium-independent organic anion transmembrane transporter activity GO:0015347 6 5 0,000 4,404E-03 0,09091361 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 4,404E-03 0,09039112 ! negative regulation of transmembrane transport GO:0034763 5 5 0,000 4,404E-03 0,0898746 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! hypothalamus development GO:0021854 5 5 0,000 4,404E-03 0,08936395 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 4,404E-03 0,08885907 ! N-terminal protein lipidation GO:0006498 5 5 0,000 4,404E-03 0,08835986 ! glycolipid transport GO:0046836 5 5 0,000 4,404E-03 0,08786623 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 5 5 0,000 4,404E-03 0,08737809 ! phosphoinositide 3-kinase binding GO:0043548 5 5 0,000 4,404E-03 0,08689533 ! protein amino acid sulfation GO:0006477 5 5 0,000 4,404E-03 0,08641789 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 6 5 0,000 4,404E-03 0,08594566 ! embryonic camera-type eye development GO:0031076 7 5 0,000 4,404E-03 0,08547856 GO:0048596|embryonic camera-type eye morphogenesis, ! opioid peptide activity GO:0001515 5 5 0,000 4,404E-03 0,08501652 ! selenocysteine incorporation GO:0001514 5 5 0,000 4,404E-03 0,08455944 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 5 5 0,000 4,404E-03 0,08410725 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 5 5 0,000 4,404E-03 0,08365987 ! elastic fiber assembly GO:0048251 5 5 0,000 4,404E-03 0,08321722 ! regulation of mitochondrial membrane permeability GO:0046902 5 5 0,000 4,404E-03 0,08277924 ! neurofilament cytoskeleton organization GO:0060052 5 5 0,000 4,404E-03 0,08234584 ! ruffle membrane GO:0032587 5 5 0,000 4,404E-03 0,08191696 ! regulation of histone modification GO:0031056 5 5 0,000 4,404E-03 0,08149251 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 4,404E-03 0,08107245 ! behavioral response to pain GO:0048266 5 5 0,000 4,404E-03 0,08065669 ! clathrin coat assembly GO:0048268 6 5 0,000 4,404E-03 0,08024518 ! Notch receptor processing GO:0007220 5 5 0,000 4,404E-03 0,07983784 ! cerebral cortex radially oriented cell migration GO:0021799 5 5 0,000 4,404E-03 0,07943462 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 6 5 0,000 4,404E-03 0,07903545 ! serotonin receptor signaling pathway GO:0007210 5 5 0,000 4,404E-03 0,07864028 ! oxidoreductase activity, oxidizing metal ions GO:0016722 5 5 0,000 4,404E-03 0,07824903 ! response to lipid GO:0033993 5 5 0,000 4,404E-03 0,07786166 ! cytoplasmic dynein complex GO:0005868 6 5 0,000 4,404E-03 0,07747811 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 4,404E-03 0,07709831 ! positive regulation of muscle cell differentiation GO:0051149 5 5 0,000 4,404E-03 0,07672222 ! smooth muscle cell differentiation GO:0051145 5 5 0,000 4,404E-03 0,07634978 ! exo-alpha-sialidase activity GO:0004308 5 5 0,000 4,404E-03 0,07598094 GO:0016997|alpha-sialidase activity, ! regulation of odontogenesis GO:0042481 5 5 0,000 4,404E-03 0,07561565 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 4,404E-03 0,07525385 ! formate-tetrahydrofolate ligase activity GO:0004329 5 5 0,000 4,404E-03 0,0748955 ! negative regulation of heart contraction GO:0045822 5 5 0,000 4,404E-03 0,07454055 ! ovulation from ovarian follicle GO:0001542 5 5 0,000 4,404E-03 0,07418894 ! DNA ligation during DNA repair GO:0051103 5 5 0,000 4,404E-03 0,07384064 ! 1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 5 5 0,000 4,404E-03 0,07349559 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 4,404E-03 0,07315375 ! negative regulation of endocytosis GO:0045806 5 5 0,000 4,404E-03 0,07281507 ! microfibril GO:0001527 5 5 0,000 4,404E-03 0,07247952 GO:0043205|fibril, ! parathyroid gland development GO:0060017 5 5 0,000 4,404E-03 0,07214704 ! toxin metabolic process GO:0009404 5 5 0,000 4,404E-03 0,0718176 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 4,404E-03 0,07149116 ! cytokine secretion GO:0050663 5 5 0,000 4,404E-03 0,07116767 ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 5 5 0,000 4,404E-03 0,0708471 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 4,404E-03 0,0705294 ! skeletal myofibril assembly GO:0014866 5 5 0,000 4,404E-03 0,07021453 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 5 0,000 4,404E-03 0,06990247 ! epithelial cell proliferation GO:0050673 5 5 0,000 4,404E-03 0,06959317 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 5 5 0,000 4,404E-03 0,06928659 ! negative regulation of survival gene product expression GO:0008634 5 5 0,000 4,404E-03 0,0689827 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 4,404E-03 0,06868146 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of defense response to virus by host GO:0050691 5 5 0,000 4,404E-03 0,06838285 ! transmembrane-ephrin receptor activity GO:0005005 5 5 0,000 4,404E-03 0,06808682 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 4,404E-03 0,06779334 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 4,404E-03 0,06750238 ! glutamate catabolic process GO:0006538 6 5 0,000 4,404E-03 0,06721391 ! positive regulation of isotype switching to IgG isotypes GO:0048304 9 5 0,000 4,404E-03 0,0669279 ! microvillus organization GO:0032528 5 5 0,000 4,404E-03 0,0666443 GO:0030033|microvillus assembly, ! tyrosine catabolic process GO:0006572 5 5 0,000 4,404E-03 0,0663631 ! L-serine biosynthetic process GO:0006564 5 5 0,000 4,404E-03 0,06608427 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 4,404E-03 0,06580776 ! pericentriolar material GO:0000242 6 5 0,000 4,404E-03 0,06553356 ! polyol biosynthetic process GO:0046173 5 5 0,000 4,404E-03 0,06526164 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 6 5 0,000 4,404E-03 0,06499196 ! platelet-derived growth factor alpha-receptor activity GO:0005018 5 5 0,000 4,404E-03 0,06472451 ! proton-transporting V-type ATPase, V0 domain GO:0033179 5 5 0,000 4,404E-03 0,06445924 ! fibroblast growth factor receptor activity GO:0005007 5 5 0,000 4,404E-03 0,06419614 ! protein-DNA loading ATPase activity GO:0033170 5 5 0,000 4,404E-03 0,06393518 GO:0003689|DNA clamp loader activity, ! insulin-like growth factor receptor activity GO:0005010 5 5 0,000 4,404E-03 0,06367634 ! response to tumor necrosis factor GO:0034612 6 5 0,000 4,404E-03 0,06341958 ! mRNA transcription GO:0009299 6 5 0,000 4,404E-03 0,06316488 ! response to ATP GO:0033198 5 5 0,000 4,404E-03 0,06291222 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 5 5 0,000 4,404E-03 0,06266158 ! adenosine receptor activity, G-protein coupled GO:0001609 5 5 0,000 4,404E-03 0,06241292 ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 4,404E-03 0,06216623 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 5 5 0,000 4,404E-03 0,06192148 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 4,404E-03 0,06167865 ! multivesicular body GO:0005771 5 5 0,000 4,404E-03 0,06143772 ! positive regulation of transporter activity GO:0032411 5 5 0,000 4,404E-03 0,06119866 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 5 5 0,000 4,404E-03 0,06096145 ! forebrain neuron development GO:0021884 6 5 0,000 4,404E-03 0,06072608 ! insulin-like growth factor I binding GO:0031994 5 5 0,000 4,404E-03 0,06049252 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 5 5 0,000 4,404E-03 0,06026075 ! demethylase activity GO:0032451 5 5 0,000 4,404E-03 0,06003075 ! peptidyl-histidine phosphorylation GO:0018106 5 5 0,000 4,404E-03 0,05980249 ! epithelial cell maturation GO:0002070 5 5 0,000 4,404E-03 0,05957597 ! nitric-oxide synthase regulator activity GO:0030235 5 5 0,000 4,404E-03 0,05935115 ! regulation of immunoglobulin secretion GO:0051023 5 5 0,000 4,404E-03 0,05912803 ! zymogen granule GO:0042588 5 5 0,000 4,404E-03 0,05890657 ! guanylate cyclase regulator activity GO:0030249 5 5 0,000 4,404E-03 0,05868677 GO:0010851|cyclase regulator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 4,404E-03 0,05846861 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,404E-03 0,05825206 ! early endosome to late endosome transport GO:0045022 5 5 0,000 4,404E-03 0,0580371 ! positive regulation of translational initiation GO:0045948 5 5 0,000 4,404E-03 0,05782373 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 4,404E-03 0,05761192 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 4,404E-03 0,05740166 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! semaphorin receptor activity GO:0017154 6 5 0,000 4,404E-03 0,05719293 ! proteoglycan binding GO:0043394 9 5 0,000 4,404E-03 0,05698571 ! regulation of collagen metabolic process GO:0010712 6 5 0,000 4,404E-03 0,05677998 ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 6 5 0,000 4,404E-03 0,05657574 ! zinc ion homeostasis GO:0055069 5 5 0,000 4,404E-03 0,05637296 GO:0006882|cellular zinc ion homeostasis, ! deoxyribonucleoside metabolic process GO:0009120 6 5 0,000 4,404E-03 0,05617163 ! nucleoside monophosphate catabolic process GO:0009125 5 5 0,000 4,404E-03 0,05597173 ! activated T cell proliferation GO:0050798 6 5 0,000 4,404E-03 0,05577325 ! advanced glycation end-product receptor activity GO:0050785 5 5 0,000 4,404E-03 0,05557617 ! dynein binding GO:0045502 5 5 0,000 4,404E-03 0,05538048 ! regulation of dendrite development GO:0050773 5 5 0,000 4,404E-03 0,05518616 ! cardiac muscle cell development GO:0055013 5 5 0,000 4,404E-03 0,0549932 ! anterograde axon cargo transport GO:0008089 5 5 0,000 4,404E-03 0,05480159 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,404E-03 0,0546113 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 4,404E-03 0,05442234 GO:0003923|GPI-anchor transamidase activity, ! lymphoid progenitor cell differentiation GO:0002320 5 5 0,000 4,404E-03 0,05423467 ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 4,404E-03 0,0540483 ! MutLalpha complex binding GO:0032405 6 5 0,000 4,404E-03 0,0538632 ! sphingomyelin catabolic process GO:0006685 6 5 0,000 4,404E-03 0,05367937 ! high-density lipoprotein binding GO:0008035 5 5 0,000 4,404E-03 0,05349679 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 4,404E-03 0,05331544 ! positive regulation of B cell differentiation GO:0045579 5 5 0,000 4,404E-03 0,05313532 ! regulation of acetylcholine secretion GO:0014056 5 5 0,000 4,404E-03 0,05295642 ! centromeric DNA binding GO:0019237 5 5 0,000 4,404E-03 0,05277871 ! cyclohydrolase activity GO:0019238 5 5 0,000 4,404E-03 0,05260219 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 4,404E-03 0,05242685 ! positive T cell selection GO:0043368 9 5 0,000 4,404E-03 0,05225268 ! neural tube patterning GO:0021532 5 5 0,000 4,404E-03 0,05207965 ! amylase activity GO:0016160 5 5 0,000 4,404E-03 0,05190777 ! metaphase plate congression GO:0051310 5 5 0,000 4,404E-03 0,05173702 ! regulation of sterol transport GO:0032371 5 5 0,000 4,404E-03 0,05156739 GO:0032374|regulation of cholesterol transport, ! sympathetic nervous system development GO:0048485 5 5 0,000 4,404E-03 0,05139887 ! oxygen homeostasis GO:0032364 5 5 0,000 4,404E-03 0,05123145 ! skeletal muscle regeneration GO:0043403 5 5 0,000 4,404E-03 0,05106511 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 5 5 0,000 4,404E-03 0,05089986 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 5 5 0,000 4,404E-03 0,05073566 ! SAP kinase activity GO:0016909 5 5 0,000 4,404E-03 0,05057253 ! positive regulation of pseudopodium assembly GO:0031274 5 5 0,000 4,404E-03 0,05041043 GO:0031272|regulation of pseudopodium assembly, ! phosphatidylserine binding GO:0001786 5 5 0,000 4,404E-03 0,05024938 ! alpha-mannosidase activity GO:0004559 6 5 0,000 4,404E-03 0,05008935 ! alpha-glucosidase activity GO:0004558 6 5 0,000 4,404E-03 0,04993033 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 4,404E-03 0,04977233 ! myeloid dendritic cell activation GO:0001773 5 5 0,000 4,404E-03 0,04961532 GO:0043011|myeloid dendritic cell differentiation, ! anaphase GO:0051322 5 5 0,000 4,404E-03 0,04945929 GO:0000090|mitotic anaphase, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 4,404E-03 0,04930425 ! ribonuclease H activity GO:0004523 5 5 0,000 4,404E-03 0,04915017 ! CARD domain binding GO:0050700 5 5 0,000 4,404E-03 0,04899706 ! regulation of muscle cell apoptosis GO:0010660 5 5 0,000 4,404E-03 0,04884489 ! AP-2 adaptor complex GO:0030122 5 5 0,000 4,404E-03 0,04869367 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 5 5 0,000 4,404E-03 0,04854338 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 4,404E-03 0,04839402 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 4,404E-03 0,04824557 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 4,404E-03 0,04809803 ! negative regulation of macrophage differentiation GO:0045650 5 5 0,000 4,404E-03 0,04795139 ! negative regulation of osteoclast differentiation GO:0045671 5 5 0,000 4,404E-03 0,04780564 ! ceramidase activity GO:0017040 5 5 0,000 4,404E-03 0,04766077 ! negative regulation of osteoblast differentiation GO:0045668 6 5 0,000 4,404E-03 0,04751678 ! GTP-Rho binding GO:0017049 5 5 0,000 4,404E-03 0,04737366 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 4,404E-03 0,0472314 ! chondroitin sulfotransferase activity GO:0034481 5 5 0,000 4,404E-03 0,04708999 ! positive regulation of T-helper 2 cell differentiation GO:0045630 5 5 0,000 4,404E-03 0,04694942 ! alcohol transmembrane transporter activity GO:0015665 5 5 0,000 4,404E-03 0,04680969 GO:0015166|polyol transmembrane transporter activity, ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 4,404E-03 0,04667079 ! TAP complex GO:0042825 5 5 0,000 4,404E-03 0,04653271 ! bHLH transcription factor binding GO:0043425 5 5 0,000 4,404E-03 0,04639544 ! actinin binding GO:0042805 6 5 0,000 4,404E-03 0,04625899 ! secretory granule organization GO:0033363 5 5 0,000 4,404E-03 0,04612333 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 5 5 0,000 4,404E-03 0,04598847 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 4,404E-03 0,04585439 ! striatum development GO:0021756 5 5 0,000 4,404E-03 0,04572109 ! photoreceptor inner segment GO:0001917 5 5 0,000 4,404E-03 0,04558857 ! regulation of T cell mediated cytotoxicity GO:0001914 9 5 0,000 4,404E-03 0,04545681 ! aldehyde-lyase activity GO:0016832 5 5 0,000 4,404E-03 0,04532581 ! regulation of mitochondrial depolarization GO:0051900 5 5 0,000 4,404E-03 0,04519556 ! T cell activation during immune response GO:0002286 5 5 0,000 4,404E-03 0,04506606 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 4,404E-03 0,0449373 ! 1-aminocyclopropane-1-carboxylate synthase activity GO:0016847 5 5 0,000 4,404E-03 0,04480927 ! dystroglycan complex GO:0016011 6 5 0,000 4,404E-03 0,04468198 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 5 5 0,000 4,404E-03 0,0445554 ! neural plate development GO:0001840 5 5 0,000 4,404E-03 0,04442953 ! toll-like receptor signaling pathway GO:0002224 5 5 0,000 4,404E-03 0,04430438 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 4,404E-03 0,04417993 ! phosphopantetheine binding GO:0031177 5 5 0,000 4,404E-03 0,04405618 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 4,404E-03 0,04393312 ! negative regulation of actin filament bundle formation GO:0032232 8 5 0,000 4,404E-03 0,04381074 GO:0051497|negative regulation of stress fiber formation, ! organ or tissue specific immune response GO:0002251 5 5 0,000 4,404E-03 0,04368904 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 4,404E-03 0,04356802 ! diacylglycerol metabolic process GO:0046339 5 5 0,000 4,404E-03 0,04344767 ! cytoplasmic microtubule organization GO:0031122 5 5 0,000 4,404E-03 0,04332798 ! retina homeostasis GO:0001895 5 5 0,000 4,404E-03 0,04320894 ! release of sequestered calcium ion into cytosol GO:0051209 10 5 0,000 4,404E-03 0,04309056 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 5 5 0,000 4,404E-03 0,04297283 ! regulation of growth hormone secretion GO:0060123 6 5 0,000 4,404E-03 0,04285574 ! collagen type IV GO:0005587 5 5 0,000 4,404E-03 0,04273928 ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 4,404E-03 0,04262346 ! testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045 5 5 0,000 4,404E-03 0,04250826 ! retrograde protein transport, ER to cytosol GO:0030970 5 5 0,000 4,404E-03 0,04239368 ! spindle assembly GO:0051225 5 5 0,000 4,404E-03 0,04227972 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,404E-03 0,04216637 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 5 5 0,000 4,404E-03 0,04205362 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 5 5 0,000 4,404E-03 0,04194148 ! protein amino acid prenylation GO:0018346 5 5 0,000 4,404E-03 0,04182993 ! stem cell division GO:0017145 5 5 0,000 4,404E-03 0,04171898 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 4,404E-03 0,04160861 ! phospholipid scrambling GO:0017121 5 5 0,000 4,404E-03 0,04149883 GO:0017128|phospholipid scramblase activity, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 5 0,000 4,404E-03 0,04138962 ! regulation of humoral immune response GO:0002920 9 5 0,000 4,404E-03 0,04128099 ! H3/H4 histone acetyltransferase activity GO:0004406 5 5 0,000 4,404E-03 0,04117292 ! regulation of interferon-alpha biosynthetic process GO:0045354 6 5 0,000 4,404E-03 0,04106542 ! negative regulation of protein ubiquitination GO:0031397 5 5 0,000 4,404E-03 0,04095848 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 4,404E-03 0,04085209 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 5 5 0,000 4,404E-03 0,04074626 GO:0030816|positive regulation of cAMP metabolic process, ! phagocytic vesicle GO:0045335 5 5 0,000 4,404E-03 0,04064097 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 4,404E-03 0,04053623 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 4,404E-03 0,04043202 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 4,404E-03 0,04032835 ! polyol transport GO:0015791 6 5 0,000 4,404E-03 0,04022521 ! cell adhesion mediated by integrin GO:0033627 6 5 0,000 4,404E-03 0,04012259 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 4,404E-03 0,0400205 ! glycerol-3-phosphate metabolic process GO:0006072 5 5 0,000 4,404E-03 0,03991892 ! platelet activating factor metabolic process GO:0046469 5 5 0,000 4,404E-03 0,03981786 ! cobalt ion transport GO:0006824 5 5 0,000 4,404E-03 0,03971731 ! response to zinc ion GO:0010043 5 5 0,000 4,404E-03 0,03961727 ! poly(U) RNA binding GO:0008266 5 5 0,000 4,404E-03 0,03951773 ! negative regulation of cell-cell adhesion GO:0022408 5 5 0,000 4,404E-03 0,03941869 ! adaptation of signaling pathway GO:0022401 5 5 0,000 4,404E-03 0,03932014 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! glucocorticoid receptor signaling pathway GO:0042921 5 5 0,000 4,404E-03 0,03922208 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 5 5 0,000 4,404E-03 0,03912452 ! sensory perception of bitter taste GO:0050913 5 5 0,000 4,404E-03 0,03902743 ! regulation of dopamine uptake GO:0051584 5 5 0,000 4,404E-03 0,03893083 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! opsonization GO:0008228 5 5 0,000 4,404E-03 0,0388347 ! protein maturation by protein folding GO:0022417 5 5 0,000 4,404E-03 0,03873905 ! neuron remodeling GO:0016322 6 5 0,000 4,404E-03 0,03864387 ! neurexin binding GO:0042043 5 5 0,000 4,404E-03 0,03854916 ! sensory perception of temperature stimulus GO:0050951 5 5 0,000 4,404E-03 0,0384549 ! regulation of potassium ion transport GO:0043266 5 5 0,000 4,404E-03 0,03836111 ! low-density lipoprotein particle GO:0034362 5 5 0,000 4,404E-03 0,03826777 ! chemoattractant activity GO:0042056 5 5 0,000 4,404E-03 0,03817489 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 6 5 0,000 4,404E-03 0,03808246 ! lipoic acid binding GO:0031405 5 5 0,000 4,404E-03 0,03799047 ! lithium ion binding GO:0031403 6 5 0,000 4,404E-03 0,03789893 ! lipoprotein particle clearance GO:0034381 5 5 0,000 4,404E-03 0,03780783 ! grooming behavior GO:0007625 5 5 0,000 4,404E-03 0,03771716 ! sequestering of actin monomers GO:0042989 5 5 0,000 4,404E-03 0,03762693 ! cobalamin binding GO:0031419 5 5 0,000 4,404E-03 0,03753712 ! retinoic acid binding GO:0001972 5 5 0,000 4,404E-03 0,03744775 ! response to axon injury GO:0048678 5 5 0,000 4,404E-03 0,0373588 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 4,404E-03 0,03727027 ! regulation of activin receptor signaling pathway GO:0032925 5 5 0,000 4,404E-03 0,03718216 ! positive regulation of neurotransmitter secretion GO:0001956 5 5 0,000 4,404E-03 0,03709447 ! mitochondrial genome maintenance GO:0000002 5 5 0,000 4,404E-03 0,03700719 ! protein-lysine 6-oxidase activity GO:0004720 6 5 0,000 4,404E-03 0,03692032 ! female pronucleus GO:0001939 5 5 0,000 4,404E-03 0,03683385 ! F-actin capping protein complex GO:0008290 5 5 0,000 4,404E-03 0,03674779 ! poly(ADP-ribose) glycohydrolase activity GO:0004649 6 5 0,000 4,404E-03 0,03666213 ! spinal cord dorsal/ventral patterning GO:0021513 5 5 0,000 4,404E-03 0,03657687 ! dorsal spinal cord development GO:0021516 5 5 0,000 4,404E-03 0,03649201 ! ceramide catabolic process GO:0046514 5 5 0,000 4,404E-03 0,03640754 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 4,404E-03 0,03632345 ! neutrophil mediated immunity GO:0002446 5 5 0,000 4,404E-03 0,03623976 ! regulation of oligodendrocyte differentiation GO:0048713 5 5 0,000 4,404E-03 0,03615645 ! Rap GTPase activator activity GO:0046582 5 5 0,000 4,404E-03 0,03607352 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 6 5 0,000 4,404E-03 0,03599097 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 5 5 0,000 4,404E-03 0,0359088 ! positive regulation of filopodium assembly GO:0051491 5 5 0,000 4,404E-03 0,03582701 GO:0051489|regulation of filopodium assembly, ! heart trabecula formation GO:0060347 5 5 0,000 4,404E-03 0,03574558 GO:0060343|trabecula formation, ! amine oxidase activity GO:0008131 6 5 0,000 4,404E-03 0,03566452 ! neutrophil activation GO:0042119 5 5 0,000 4,404E-03 0,03558384 ! regulation of response to food GO:0032095 5 5 0,000 4,404E-03 0,03550351 ! response to food GO:0032094 5 5 0,000 4,404E-03 0,03542355 ! hedgehog receptor activity GO:0008158 5 5 0,000 4,404E-03 0,03534394 ! protein phosphatase 1 binding GO:0008157 5 5 0,000 4,404E-03 0,0352647 ! lipoprotein catabolic process GO:0042159 5 5 0,000 4,404E-03 0,03518581 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 4,404E-03 0,03510727 ! organ growth GO:0035265 7 5 0,000 4,404E-03 0,03502908 ! positive regulation of multicellular organismal metabolic process GO:0044253 6 5 0,000 4,404E-03 0,03495123 ! small-subunit processome GO:0032040 5 5 0,000 4,404E-03 0,03487374 ! UDP-glucosyltransferase activity GO:0035251 5 5 0,000 4,404E-03 0,03479658 ! myosin heavy chain binding GO:0032036 5 5 0,000 4,404E-03 0,03471977 ! nucleoside salvage GO:0043174 7 5 0,000 4,404E-03 0,03464329 GO:0006166|purine ribonucleoside salvage, ! nucleobase transport GO:0015851 5 5 0,000 4,404E-03 0,03456715 ! GPI anchor binding GO:0034235 6 5 0,000 4,404E-03 0,03449135 ! thrombin receptor activity GO:0015057 5 5 0,000 4,404E-03 0,03441588 ! nucleotide-excision repair complex GO:0000109 6 5 0,000 4,404E-03 0,03434073 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 5 5 0,000 4,404E-03 0,03426592 ! dendritic shaft GO:0043198 5 5 0,000 4,404E-03 0,03419142 ! terminal button GO:0043195 8 5 0,000 4,404E-03 0,03411726 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 4,404E-03 0,03404341 GO:0016274|protein-arginine N-methyltransferase activity, ! ferrous iron binding GO:0008198 6 5 0,000 4,404E-03 0,03396988 ! eukaryotic initiation factor 4E binding GO:0008190 5 5 0,000 4,404E-03 0,03389667 ! G2/M transition checkpoint GO:0031576 5 5 0,000 4,404E-03 0,03382377 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of peptide secretion GO:0002792 6 5 0,000 4,404E-03 0,03375119 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 5 5 0,000 4,404E-03 0,03367892 ! response to UV-C GO:0010225 5 5 0,000 4,404E-03 0,03360696 ! carbonyl reductase (NADPH) activity GO:0004090 5 5 0,000 4,404E-03 0,0335353 ! regulation of alpha-beta T cell proliferation GO:0046640 9 5 0,000 4,404E-03 0,03346395 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! positive regulation of organ growth GO:0046622 5 5 0,000 4,404E-03 0,0333929 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 5 5 0,000 4,404E-03 0,03332215 ! IgE binding GO:0019863 5 5 0,000 4,404E-03 0,0332517 ! 3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 5 5 0,000 4,404E-03 0,03318155 ! monoamine transmembrane transporter activity GO:0008504 5 5 0,000 4,404E-03 0,0331117 ! response to cadmium ion GO:0046686 5 5 0,000 4,404E-03 0,03304213 ! regulation of interleukin-4 production GO:0032673 5 5 0,000 4,404E-03 0,03297286 ! hair follicle maturation GO:0048820 5 5 0,000 4,404E-03 0,03290388 ! regulation of interleukin-10 production GO:0032653 5 5 0,000 4,404E-03 0,03283519 ! ribosomal large subunit biogenesis GO:0042273 5 5 0,000 4,404E-03 0,03276678 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,404E-03 0,03269866 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 4,404E-03 0,03263082 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 4,404E-03 0,03256326 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 4,404E-03 0,03249598 GO:0005218|intracellular ligand-gated calcium channel activity, ! general transcriptional repressor activity GO:0016565 5 5 0,000 4,404E-03 0,03242898 ! peroxisome fission GO:0016559 5 5 0,000 4,404E-03 0,03236225 ! alpha-tubulin binding GO:0043014 5 5 0,000 4,404E-03 0,0322958 ! mitotic recombination GO:0006312 5 5 0,000 4,404E-03 0,03222962 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,404E-03 0,03216371 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 4,404E-03 0,03209807 ! positive regulation of chemokine production GO:0032722 5 5 0,000 4,404E-03 0,0320327 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 4,404E-03 0,03196759 ! muscle cell proliferation GO:0033002 5 5 0,000 4,404E-03 0,03190275 ! membrane to membrane docking GO:0022614 5 5 0,000 4,404E-03 0,03183817 ! translation activator activity GO:0008494 5 5 0,000 4,404E-03 0,03177385 ! N-formyl peptide receptor activity GO:0004982 5 5 0,000 4,404E-03 0,03170979 ! coenzyme A biosynthetic process GO:0015937 6 5 0,000 4,404E-03 0,03164599 ! histamine receptor activity GO:0004969 5 5 0,000 4,404E-03 0,03158244 ! dopamine receptor activity GO:0004952 5 5 0,000 4,404E-03 0,03151915 ! galactosidase activity GO:0015925 5 5 0,000 4,404E-03 0,03145611 ! prostaglandin E receptor activity GO:0004957 6 5 0,000 4,404E-03 0,03139332 ! cellular response to nutrient GO:0031670 5 5 0,000 4,404E-03 0,03133079 ! basic amino acid transmembrane transporter activity GO:0015174 5 5 0,000 4,404E-03 0,0312685 ! ATP-gated cation channel activity GO:0004931 7 5 0,000 4,404E-03 0,03120646 ! cytochrome-b5 reductase activity GO:0004128 5 5 0,000 4,404E-03 0,03114466 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 4,404E-03 0,03108311 ! glycine transmembrane transporter activity GO:0015187 5 5 0,000 4,404E-03 0,03102181 ! tyrosine phosphorylation of STAT protein GO:0007260 6 5 0,000 4,404E-03 0,03096074 ! tricarboxylic acid cycle enzyme complex GO:0045239 5 5 0,000 4,404E-03 0,03089991 ! RNA polymerase I transcription factor activity GO:0003701 5 5 0,000 4,404E-03 0,03083932 ! progesterone metabolic process GO:0042448 5 5 0,000 4,404E-03 0,03077897 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 5 5 0,000 4,404E-03 0,03071886 ! disaccharide metabolic process GO:0005984 5 5 0,000 4,404E-03 0,03065898 ! 5'-3' exonuclease activity GO:0008409 5 5 0,000 4,404E-03 0,03059933 ! type II transforming growth factor beta receptor binding GO:0005114 5 5 0,000 4,404E-03 0,03053991 ! histone acetyltransferase binding GO:0035035 5 5 0,000 4,404E-03 0,03048073 ! endosome to lysosome transport GO:0008333 5 5 0,000 4,404E-03 0,03042177 ! glial cell migration GO:0008347 5 5 0,000 4,404E-03 0,03036304 ! S-acyltransferase activity GO:0016417 5 5 0,000 4,404E-03 0,03030454 ! phosphoinositide 3-kinase regulator activity GO:0035014 5 5 0,000 4,404E-03 0,03024626 ! phosphatidylinositol-4-phosphate 3-kinase activity GO:0035005 5 5 0,000 4,404E-03 0,03018821 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 4,404E-03 0,03013037 ! nucleobase transmembrane transporter activity GO:0015205 5 5 0,000 4,404E-03 0,03007276 ! asparaginase activity GO:0004067 5 5 0,000 4,404E-03 0,03001537 ! insemination GO:0007320 5 5 0,000 4,404E-03 0,0299582 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 4,404E-03 0,02990125 ! negative regulation of smooth muscle contraction GO:0045986 6 5 0,000 4,404E-03 0,02984451 ! aminoacylase activity GO:0004046 5 5 0,000 4,404E-03 0,02978798 ! receptor biosynthetic process GO:0032800 5 5 0,000 4,404E-03 0,02973167 ! penetration of zona pellucida GO:0007341 5 5 0,000 4,404E-03 0,02967558 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 6 5 0,000 4,404E-03 0,02961969 ! aldehyde reductase activity GO:0004032 5 5 0,000 4,404E-03 0,02956401 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 5 0,000 4,404E-03 0,02950855 ! unconventional myosin complex GO:0016461 5 5 0,000 4,404E-03 0,02945329 ! carnitine metabolic process GO:0009437 5 5 0,000 4,404E-03 0,02939823 GO:0006577|betaine metabolic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 6 6 0,000 5,283E-03 0,03519773 ! regulation of helicase activity GO:0051095 6 6 0,000 5,283E-03 0,03513218 ! testosterone 17-beta-dehydrogenase activity GO:0050327 6 6 0,000 5,283E-03 0,03506688 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 6 6 0,000 5,283E-03 0,03500182 ! tumor necrosis factor-mediated signaling pathway GO:0033209 6 6 0,000 5,283E-03 0,03493701 ! negative regulation of small GTPase mediated signal transduction GO:0051058 7 6 0,000 5,283E-03 0,03487243 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 7 6 0,000 5,283E-03 0,03480809 ! regulation of hormone biosynthetic process GO:0046885 6 6 0,000 5,283E-03 0,03474398 ! ephrin receptor binding GO:0046875 7 6 0,000 5,283E-03 0,03468012 ! biotin binding GO:0009374 7 6 0,000 5,283E-03 0,03461648 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 5,283E-03 0,03455308 ! insulin receptor substrate binding GO:0043560 7 6 0,000 5,283E-03 0,03448991 ! drug:hydrogen antiporter activity GO:0015307 6 6 0,000 5,283E-03 0,03442698 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 5,283E-03 0,03436427 ! carbohydrate phosphorylation GO:0046835 6 6 0,000 5,283E-03 0,03430179 ! regulation of respiratory gaseous exchange GO:0043576 6 6 0,000 5,283E-03 0,03423953 ! neuron adhesion GO:0007158 6 6 0,000 5,283E-03 0,03417751 ! establishment of tissue polarity GO:0007164 7 6 0,000 5,283E-03 0,0341157 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 6 6 0,000 5,283E-03 0,03405412 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 5,283E-03 0,03399276 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 6 0,000 5,283E-03 0,03393162 ! regulation of cardiac muscle cell proliferation GO:0060043 6 6 0,000 5,283E-03 0,03387071 ! positive regulation of receptor-mediated endocytosis GO:0048260 6 6 0,000 5,283E-03 0,03381001 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 6 6 0,000 5,283E-03 0,03374952 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 5,283E-03 0,03368926 ! eukaryotic translation elongation factor 1 complex GO:0005853 6 6 0,000 5,283E-03 0,0336292 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 5,283E-03 0,03356936 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 6 6 0,000 5,283E-03 0,03350974 ! cytoplasmic microtubule GO:0005881 7 6 0,000 5,283E-03 0,03345032 ! Arp2/3 protein complex GO:0005885 7 6 0,000 5,283E-03 0,03339112 ! neurofilament GO:0005883 6 6 0,000 5,283E-03 0,03333213 ! glial cell fate commitment GO:0021781 6 6 0,000 5,283E-03 0,03327334 ! dynactin complex GO:0005869 6 6 0,000 5,283E-03 0,03321476 ! fibroblast growth factor receptor antagonist activity GO:0030353 6 6 0,000 5,283E-03 0,03315638 GO:0005104|fibroblast growth factor receptor binding, GO:0005152|interleukin-1 receptor antagonist activity, ! translation repressor activity GO:0030371 6 6 0,000 5,283E-03 0,03309822 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 6 6 0,000 5,283E-03 0,03304025 ! lipopolysaccharide binding GO:0001530 6 6 0,000 5,283E-03 0,03298249 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 5,283E-03 0,03292493 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 5,283E-03 0,03286757 ! negative regulation of viral genome replication GO:0045071 6 6 0,000 5,283E-03 0,03281041 ! traversing start control point of mitotic cell cycle GO:0007089 6 6 0,000 5,283E-03 0,03275344 ! protein lipoylation GO:0009249 6 6 0,000 5,283E-03 0,03269668 ! cysteine metabolic process GO:0006534 6 6 0,000 5,283E-03 0,03264011 ! regulation of isotype switching to IgG isotypes GO:0048302 10 6 0,000 5,283E-03 0,03258374 ! histidine catabolic process GO:0006548 6 6 0,000 5,283E-03 0,03252756 GO:0009077|histidine family amino acid catabolic process, ! centromeric heterochromatin GO:0005721 6 6 0,000 5,283E-03 0,03247157 ! mitochondrial respiratory chain complex assembly GO:0033108 6 6 0,000 5,283E-03 0,03241578 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 6 6 0,000 5,283E-03 0,03236018 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 6 6 0,000 5,283E-03 0,03230477 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 6 6 0,000 5,283E-03 0,03224954 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 6 0,000 5,283E-03 0,03219451 ! microtubule nucleation GO:0007020 6 6 0,000 5,283E-03 0,03213966 ! proline biosynthetic process GO:0006561 7 6 0,000 5,283E-03 0,03208501 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 5,283E-03 0,03203053 ! transforming growth factor beta receptor activity, type I GO:0005025 6 6 0,000 5,283E-03 0,03197624 ! phasic smooth muscle contraction GO:0014821 6 6 0,000 5,283E-03 0,03192214 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 5,283E-03 0,03186821 ! peptidoglycan metabolic process GO:0000270 6 6 0,000 5,283E-03 0,03181447 GO:0009253|peptidoglycan catabolic process, ! cerebral cortex neuron differentiation GO:0021895 6 6 0,000 5,283E-03 0,03176091 ! paraxial mesoderm development GO:0048339 6 6 0,000 5,283E-03 0,03170753 ! melanosome organization GO:0032438 6 6 0,000 5,283E-03 0,03165433 ! mitochondrial outer membrane translocase complex GO:0005742 6 6 0,000 5,283E-03 0,03160131 ! flotillin complex GO:0016600 6 6 0,000 5,283E-03 0,03154847 ! positive regulation of neuroblast proliferation GO:0002052 6 6 0,000 5,283E-03 0,0314958 ! positive regulation of vasoconstriction GO:0045907 6 6 0,000 5,283E-03 0,0314433 ! negative regulation of DNA recombination GO:0045910 6 6 0,000 5,283E-03 0,03139099 ! positive regulation of exocytosis GO:0045921 7 6 0,000 5,283E-03 0,03133884 ! protein tyrosine kinase activator activity GO:0030296 6 6 0,000 5,283E-03 0,03128687 ! positive regulation of fatty acid metabolic process GO:0045923 6 6 0,000 5,283E-03 0,03123507 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 5,283E-03 0,03118344 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of mitotic cell cycle GO:0045931 6 6 0,000 5,283E-03 0,03113199 ! nonhomologous end joining complex GO:0070419 6 6 0,000 5,283E-03 0,0310807 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! vinculin binding GO:0017166 6 6 0,000 5,283E-03 0,03102958 ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 5,283E-03 0,03097863 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 5,283E-03 0,03092784 ! sodium ion homeostasis GO:0055078 6 6 0,000 5,283E-03 0,03087722 ! protein heterooligomerization GO:0051291 6 6 0,000 5,283E-03 0,03082677 ! negative regulation of gliogenesis GO:0014014 6 6 0,000 5,283E-03 0,03077648 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 8 6 0,000 5,283E-03 0,03072636 ! translation termination factor activity GO:0008079 6 6 0,000 5,283E-03 0,0306764 GO:0003747|translation release factor activity, ! centrosome duplication GO:0051298 6 6 0,000 5,283E-03 0,0306266 ! astrocyte development GO:0014002 6 6 0,000 5,283E-03 0,03057696 ! protein targeting to lysosome GO:0006622 6 6 0,000 5,283E-03 0,03052748 ! purine base biosynthetic process GO:0009113 7 6 0,000 5,283E-03 0,03047816 ! fibrinolysis GO:0042730 7 6 0,000 5,283E-03 0,030429 ! peptidyl-asparagine modification GO:0018196 6 6 0,000 5,283E-03 0,03038 GO:0018279|protein amino acid N-linked glycosylation via asparagine, GO:0004579|dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ! eating behavior GO:0042755 6 6 0,000 5,283E-03 0,03033116 ! B cell lineage commitment GO:0002326 6 6 0,000 5,283E-03 0,03028248 ! thiamin and derivative metabolic process GO:0042723 6 6 0,000 5,283E-03 0,03023395 ! response to exogenous dsRNA GO:0043330 6 6 0,000 5,283E-03 0,03018557 ! enucleate erythrocyte differentiation GO:0043353 6 6 0,000 5,283E-03 0,03013735 ! melanosome transport GO:0032402 6 6 0,000 5,283E-03 0,03008929 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 6 6 0,000 5,283E-03 0,03004137 GO:0014066|regulation of phosphoinositide 3-kinase cascade, ! mast cell activation GO:0045576 6 6 0,000 5,283E-03 0,02999361 ! regulation of dopamine secretion GO:0014059 6 6 0,000 5,283E-03 0,029946 ! regulation of protein kinase B signaling cascade GO:0051896 6 6 0,000 5,283E-03 0,02989855 ! negative regulation of focal adhesion formation GO:0051895 8 6 0,000 5,283E-03 0,02985124 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,283E-03 0,02980408 ! transcription initiation factor activity GO:0016986 6 6 0,000 5,283E-03 0,02975707 ! negative regulation of T cell differentiation GO:0045581 6 6 0,000 5,283E-03 0,02971021 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 5,283E-03 0,0296635 ! Schwann cell development GO:0014044 6 6 0,000 5,283E-03 0,02961693 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 6 0,000 5,283E-03 0,02957051 ! G-protein coupled photoreceptor activity GO:0008020 6 6 0,000 5,283E-03 0,02952423 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 5,283E-03 0,0294781 ! regulation of chondrocyte differentiation GO:0032330 6 6 0,000 5,283E-03 0,02943211 ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 5,283E-03 0,02938627 ! superoxide-generating NADPH oxidase activity GO:0016175 6 6 0,000 5,283E-03 0,02934056 ! nuclear envelope lumen GO:0005641 6 6 0,000 5,283E-03 0,029295 ! RNA polymerase II transcription elongation factor activity GO:0016944 7 6 0,000 5,283E-03 0,02924959 ! regulation of meiosis GO:0040020 6 6 0,000 5,283E-03 0,02920431 GO:0051445|regulation of meiotic cell cycle, ! establishment of nucleus localization GO:0040023 8 6 0,000 5,283E-03 0,02915917 ! lipoxygenase activity GO:0016165 6 6 0,000 5,283E-03 0,02911417 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 5,283E-03 0,02906931 ! alpha DNA polymerase:primase complex GO:0005658 7 6 0,000 5,283E-03 0,02902459 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 5,283E-03 0,02898 ! DNA replication factor C complex GO:0005663 6 6 0,000 5,283E-03 0,02893556 ! nuclear origin of replication recognition complex GO:0005664 6 6 0,000 5,283E-03 0,02889124 GO:0000808|origin recognition complex, ! DNA replication factor A complex GO:0005662 6 6 0,000 5,283E-03 0,02884707 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 5,283E-03 0,02880303 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 5,283E-03 0,02875912 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 5,283E-03 0,02871535 ! chromatin silencing complex GO:0005677 6 6 0,000 5,283E-03 0,02867171 GO:0034979|NAD-dependent protein deacetylase activity, GO:0017136|NAD-dependent histone deacetylase activity, ! U12-type spliceosomal complex GO:0005689 7 6 0,000 5,283E-03 0,0286282 ! B cell homeostasis GO:0001782 7 6 0,000 5,283E-03 0,02858482 ! regulation of respiratory burst GO:0060263 6 6 0,000 5,283E-03 0,02854158 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 10 6 0,000 5,283E-03 0,02849846 GO:0002820|negative regulation of adaptive immune response, ! immunological synapse GO:0001772 6 6 0,000 5,283E-03 0,02845548 ! MutLalpha complex GO:0032389 6 6 0,000 5,283E-03 0,02841262 ! leading edge membrane GO:0031256 6 6 0,000 5,283E-03 0,0283699 ! bis(5'-adenosyl)-triphosphatase activity GO:0047710 6 6 0,000 5,283E-03 0,0283273 ! peptidyl-histidine modification GO:0018202 6 6 0,000 5,283E-03 0,02828483 ! exodeoxyribonuclease activity GO:0004529 6 6 0,000 5,283E-03 0,02824249 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! COPII vesicle coat GO:0030127 6 6 0,000 5,283E-03 0,02820027 GO:0012507|ER to Golgi transport vesicle membrane, ! peptidyl-threonine modification GO:0018210 6 6 0,000 5,283E-03 0,02815818 ! diuresis GO:0030146 6 6 0,000 5,283E-03 0,02811622 GO:0030147|natriuresis, ! definitive hemopoiesis GO:0060216 6 6 0,000 5,283E-03 0,02807438 ! glutathione biosynthetic process GO:0006750 6 6 0,000 5,283E-03 0,02803266 ! HLA-B specific inhibitory MHC class I receptor activity GO:0030109 6 6 0,000 5,283E-03 0,02799107 ! BBSome GO:0034464 6 6 0,000 5,283E-03 0,0279496 ! regulation of keratinocyte differentiation GO:0045616 6 6 0,000 5,283E-03 0,02790826 ! glycerophosphodiester phosphodiesterase activity GO:0008889 6 6 0,000 5,283E-03 0,02786704 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 5,283E-03 0,02782593 ! sodium channel regulator activity GO:0017080 6 6 0,000 5,283E-03 0,02778495 ! glycolipid catabolic process GO:0019377 6 6 0,000 5,283E-03 0,02774409 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 6 6 0,000 5,283E-03 0,02770335 ! nicotinamide nucleotide biosynthetic process GO:0019359 6 6 0,000 5,283E-03 0,02766273 ! porphyrin catabolic process GO:0006787 8 6 0,000 5,283E-03 0,02762223 GO:0033015|tetrapyrrole catabolic process, ! removal of superoxide radicals GO:0019430 6 6 0,000 5,283E-03 0,02758185 ! positive regulation of glucose import GO:0046326 7 6 0,000 5,283E-03 0,02754158 GO:0010828|positive regulation of glucose transport, ! triglyceride catabolic process GO:0019433 6 6 0,000 5,283E-03 0,02750143 ! myeloid cell homeostasis GO:0002262 6 6 0,000 5,283E-03 0,0274614 ! lamin binding GO:0005521 6 6 0,000 5,283E-03 0,02742149 ! ectodermal gut morphogenesis GO:0048567 6 6 0,000 5,283E-03 0,02738169 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 6 6 0,000 5,283E-03 0,027342 ! pattern recognition receptor signaling pathway GO:0002221 6 6 0,000 5,283E-03 0,02730244 ! negative regulation of calcium ion transport GO:0051926 6 6 0,000 5,283E-03 0,02726298 ! peroxiredoxin activity GO:0051920 6 6 0,000 5,283E-03 0,02722364 ! complement binding GO:0001848 8 6 0,000 5,283E-03 0,02718441 ! catecholamine transport GO:0051937 6 6 0,000 5,283E-03 0,0271453 ! regulation of sensory perception GO:0051931 6 6 0,000 5,283E-03 0,0271063 GO:0051930|regulation of sensory perception of pain, ! muscle adaptation GO:0043500 6 6 0,000 5,283E-03 0,02706741 ! hemopoietic progenitor cell differentiation GO:0002244 6 6 0,000 5,283E-03 0,02702863 ! dipeptidase activity GO:0016805 6 6 0,000 5,283E-03 0,02698996 ! ether hydrolase activity GO:0016803 6 6 0,000 5,283E-03 0,0269514 ! FACIT collagen GO:0005593 6 6 0,000 5,283E-03 0,02691296 ! actin filament polymerization GO:0030041 8 6 0,000 5,283E-03 0,02687462 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 5,283E-03 0,02683639 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 6 6 0,000 5,283E-03 0,02679827 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 6 0,000 5,283E-03 0,02676026 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 5,283E-03 0,02672236 ! negative regulation of synaptic transmission GO:0050805 7 6 0,000 5,283E-03 0,02668456 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 5,283E-03 0,02664687 ! organ regeneration GO:0031100 6 6 0,000 5,283E-03 0,02660928 ! Golgi transport complex GO:0017119 6 6 0,000 5,283E-03 0,02657181 ! sheet-forming collagen GO:0030935 6 6 0,000 5,283E-03 0,02653443 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 5,283E-03 0,02649717 ! positive regulation of coagulation GO:0050820 7 6 0,000 5,283E-03 0,02646 ! defense response to Gram-negative bacterium GO:0050829 6 6 0,000 5,283E-03 0,02642295 ! positive regulation of MHC class II biosynthetic process GO:0045348 6 6 0,000 5,283E-03 0,02638599 GO:0045346|regulation of MHC class II biosynthetic process, ! thioredoxin-disulfide reductase activity GO:0004791 6 6 0,000 5,283E-03 0,02634914 ! sphingomyelin phosphodiesterase activity GO:0004767 7 6 0,000 5,283E-03 0,02631239 ! regulation of cGMP metabolic process GO:0030823 6 6 0,000 5,283E-03 0,02627574 ! myoblast cell fate commitment GO:0048625 6 6 0,000 5,283E-03 0,0262392 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 5,283E-03 0,02620275 ! DNA synthesis during DNA repair GO:0000731 7 6 0,000 5,283E-03 0,02616641 ! neutral lipid biosynthetic process GO:0046460 6 6 0,000 5,283E-03 0,02613017 GO:0046463|acylglycerol biosynthetic process, ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 6 6 0,000 5,283E-03 0,02609403 ! nuclear telomere cap complex GO:0000783 6 6 0,000 5,283E-03 0,02605799 GO:0000782|telomere cap complex, ! Golgi to endosome transport GO:0006895 6 6 0,000 5,283E-03 0,02602205 ! negative regulation of JAK-STAT cascade GO:0046426 7 6 0,000 5,283E-03 0,0259862 ! sterol carrier activity GO:0005498 6 6 0,000 5,283E-03 0,02595046 ! positive regulation of cell-cell adhesion GO:0022409 6 6 0,000 5,283E-03 0,02591481 ! succinate metabolic process GO:0006105 6 6 0,000 5,283E-03 0,02587926 ! myelin sheath GO:0043209 6 6 0,000 5,283E-03 0,02584381 ! perikaryon GO:0043204 7 6 0,000 5,283E-03 0,02580846 ! oxaloacetate metabolic process GO:0006107 7 6 0,000 5,283E-03 0,0257732 ! malate metabolic process GO:0006108 6 6 0,000 5,283E-03 0,02573804 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 6 6 0,000 5,283E-03 0,02570297 ! posttranscriptional gene silencing by RNA GO:0035194 6 6 0,000 5,283E-03 0,025668 GO:0016441|posttranscriptional gene silencing, ! mating behavior GO:0007617 6 6 0,000 5,283E-03 0,02563313 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 5,283E-03 0,02559835 ! rhythmic behavior GO:0007622 7 6 0,000 5,283E-03 0,02556366 ! copulation GO:0007620 6 6 0,000 5,283E-03 0,02552907 ! erythrocyte maturation GO:0043249 6 6 0,000 5,283E-03 0,02549457 ! equilibrioception GO:0050957 6 6 0,000 5,283E-03 0,02546017 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 5,283E-03 0,02542585 ! G-protein coupled receptor kinase activity GO:0004703 6 6 0,000 5,283E-03 0,02539163 ! chemosensory behavior GO:0007635 6 6 0,000 5,283E-03 0,0253575 ! synaptic transmission, dopaminergic GO:0001963 7 6 0,000 5,283E-03 0,02532347 ! mechanosensory behavior GO:0007638 6 6 0,000 5,283E-03 0,02528952 ! response to interferon-gamma GO:0034341 6 6 0,000 5,283E-03 0,02525567 ! spinal cord patterning GO:0021511 6 6 0,000 5,283E-03 0,0252219 ! cGMP-mediated signaling GO:0019934 6 6 0,000 5,283E-03 0,02518823 ! protein geranylgeranyltransferase activity GO:0004661 6 6 0,000 5,283E-03 0,02515464 ! activation of MAPKKK activity GO:0000185 6 6 0,000 5,283E-03 0,02512115 ! nerve growth factor receptor signaling pathway GO:0048011 8 6 0,000 5,283E-03 0,02508774 ! glucosyltransferase activity GO:0046527 6 6 0,000 5,283E-03 0,02505443 ! sphingoid catabolic process GO:0046521 6 6 0,000 5,283E-03 0,0250212 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 5,283E-03 0,02498806 ! activin receptor activity GO:0017002 6 6 0,000 5,283E-03 0,024955 ! ovulation GO:0030728 6 6 0,000 5,283E-03 0,02492204 ! dopamine binding GO:0035240 7 6 0,000 5,283E-03 0,02488916 ! hyperosmotic response GO:0006972 6 6 0,000 5,283E-03 0,02485637 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 6 6 0,000 5,283E-03 0,02482366 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 6 0,000 5,283E-03 0,02479104 ! nuclear localization sequence binding GO:0008139 6 6 0,000 5,283E-03 0,02475851 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 5,283E-03 0,02472606 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 5,283E-03 0,02469369 ! copper ion transmembrane transporter activity GO:0005375 6 6 0,000 5,283E-03 0,02466142 ! poly(A) RNA binding GO:0008143 6 6 0,000 5,283E-03 0,02462922 ! positive transcription elongation factor activity GO:0008159 6 6 0,000 5,283E-03 0,02459711 ! regulation of glycogen metabolic process GO:0070873 7 6 0,000 5,283E-03 0,02456508 GO:0032881|regulation of polysaccharide metabolic process, ! maintenance of protein location in nucleus GO:0051457 6 6 0,000 5,283E-03 0,02453314 ! intracellular pH reduction GO:0051452 6 6 0,000 5,283E-03 0,02450128 GO:0045851|pH reduction, ! purine salvage GO:0043101 8 6 0,000 5,283E-03 0,0244695 ! nucleotide-sugar transmembrane transporter activity GO:0005338 6 6 0,000 5,283E-03 0,0244378 ! neurotrophin binding GO:0043121 6 6 0,000 5,283E-03 0,02440619 ! ciliary rootlet GO:0035253 6 6 0,000 5,283E-03 0,02437465 ! neurotransmitter catabolic process GO:0042135 10 6 0,000 5,283E-03 0,0243432 ! ruffle organization GO:0031529 6 6 0,000 5,283E-03 0,02431183 ! T cell mediated immunity GO:0002456 6 6 0,000 5,283E-03 0,02428054 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 7 6 0,000 5,283E-03 0,02424934 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! carnitine transport GO:0015879 6 6 0,000 5,283E-03 0,02421821 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 5,283E-03 0,02418716 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! palmitoyl-CoA hydrolase activity GO:0016290 6 6 0,000 5,283E-03 0,02415619 ! S-methyltransferase activity GO:0008172 6 6 0,000 5,283E-03 0,0241253 ! phospholipase D activity GO:0004630 6 6 0,000 5,283E-03 0,02409449 ! rRNA modification GO:0000154 6 6 0,000 5,283E-03 0,02406375 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 5,283E-03 0,0240331 ! neuronal ion channel clustering GO:0045161 6 6 0,000 5,283E-03 0,02400252 ! response to UV-B GO:0010224 6 6 0,000 5,283E-03 0,02397202 ! interaction with symbiont GO:0051702 6 6 0,000 5,283E-03 0,0239416 ! negative regulation of insulin receptor signaling pathway GO:0046627 6 6 0,000 5,283E-03 0,02391126 ! IgG binding GO:0019864 6 6 0,000 5,283E-03 0,02388099 ! positive regulation of cytokine production during immune response GO:0002720 6 6 0,000 5,283E-03 0,0238508 ! base-excision repair, AP site formation GO:0006285 6 6 0,000 5,283E-03 0,02382069 ! benzodiazepine receptor activity GO:0008503 6 6 0,000 5,283E-03 0,02379065 ! response to copper ion GO:0046688 6 6 0,000 5,283E-03 0,02376068 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 5,283E-03 0,0237308 ! dendrite morphogenesis GO:0048813 6 6 0,000 5,283E-03 0,02370098 ! regulation of interleukin-1 beta production GO:0032651 6 6 0,000 5,283E-03 0,02367125 ! regulation of myeloid cell apoptosis GO:0033032 6 6 0,000 5,283E-03 0,02364158 ! positive regulation of tumor necrosis factor production GO:0032760 6 6 0,000 5,283E-03 0,02361199 ! nucleosome disassembly GO:0006337 6 6 0,000 5,283E-03 0,02358248 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! inositol trisphosphate 3-kinase activity GO:0008440 6 6 0,000 5,283E-03 0,02355304 ! regulation of mast cell activation GO:0033003 6 6 0,000 5,283E-03 0,02352367 ! guanylyltransferase activity GO:0070568 6 6 0,000 5,283E-03 0,02349437 ! receptor internalization GO:0031623 7 6 0,000 5,283E-03 0,02346515 ! neuropeptide Y receptor activity GO:0004983 6 6 0,000 5,283E-03 0,023436 ! ATP-dependent peptidase activity GO:0004176 6 6 0,000 5,283E-03 0,02340693 ! serine-type carboxypeptidase activity GO:0004185 6 6 0,000 5,283E-03 0,02337792 GO:0070008|serine-type exopeptidase activity, ! protein deubiquitination GO:0016579 6 6 0,000 5,283E-03 0,02334899 ! negative regulation of neuroblast proliferation GO:0007406 6 6 0,000 5,283E-03 0,02332013 ! NuRD complex GO:0016581 6 6 0,000 5,283E-03 0,02329134 ! nucleosome positioning GO:0016584 6 6 0,000 5,283E-03 0,02326262 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 5,283E-03 0,02323397 ! alpha-adrenergic receptor activity GO:0004936 8 6 0,000 5,283E-03 0,02320539 ! glycine binding GO:0016594 8 6 0,000 5,283E-03 0,02317688 ! costamere GO:0043034 7 6 0,000 5,283E-03 0,02314845 ! A band GO:0031672 6 6 0,000 5,283E-03 0,02312008 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 5,283E-03 0,02309178 ! dopamine biosynthetic process GO:0042416 7 6 0,000 5,283E-03 0,02306355 ! procollagen-proline dioxygenase activity GO:0019798 6 6 0,000 5,283E-03 0,02303539 ! negative regulation of axon extension GO:0030517 6 6 0,000 5,283E-03 0,0230073 ! actin monomer binding GO:0003785 6 6 0,000 5,283E-03 0,02297927 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 5,283E-03 0,02295132 ! lysozyme activity GO:0003796 6 6 0,000 5,283E-03 0,02292343 ! regulation of Rac protein signal transduction GO:0035020 6 6 0,000 5,283E-03 0,02289561 ! ATP catabolic process GO:0006200 6 6 0,000 5,283E-03 0,02286786 ! determination of adult lifespan GO:0008340 6 6 0,000 5,283E-03 0,02284017 ! somatic stem cell maintenance GO:0035019 6 6 0,000 5,283E-03 0,02281255 ! negative regulation of organic acid transport GO:0032891 6 6 0,000 5,283E-03 0,022785 ! establishment of apical/basal cell polarity GO:0035089 6 6 0,000 5,283E-03 0,02275752 ! calcium-dependent phospholipase A2 activity GO:0047498 6 6 0,000 5,283E-03 0,0227301 ! O-acetyltransferase activity GO:0016413 6 6 0,000 5,283E-03 0,02270275 ! CoA-ligase activity GO:0016405 6 6 0,000 5,283E-03 0,02267546 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 5,283E-03 0,02264824 ! IkappaB kinase complex GO:0008385 6 6 0,000 5,283E-03 0,02262108 ! pyrimidine nucleotide catabolic process GO:0006244 6 6 0,000 5,283E-03 0,02259399 ! store-operated calcium channel activity GO:0015279 6 6 0,000 5,283E-03 0,02256697 ! aminomethyltransferase activity GO:0004047 6 6 0,000 5,283E-03 0,02254 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 6 6 0,000 5,283E-03 0,02251311 ! alkaline phosphatase activity GO:0004035 6 6 0,000 5,283E-03 0,02248627 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 6 6 0,000 5,283E-03 0,0224595 ! oligosaccharide biosynthetic process GO:0009312 7 7 0,000 6,161E-03 0,02616094 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 6,161E-03 0,02612987 ! sleep GO:0030431 7 7 0,000 6,161E-03 0,02609888 ! synaptonemal complex assembly GO:0007130 7 7 0,000 6,161E-03 0,02606795 GO:0070193|synaptonemal complex organization, ! forebrain regionalization GO:0021871 7 7 0,000 6,161E-03 0,02603711 ! cell proliferation in forebrain GO:0021846 7 7 0,000 6,161E-03 0,02600633 ! proteasome regulatory particle GO:0005838 8 7 0,000 6,161E-03 0,02597562 ! meiotic prophase I GO:0007128 7 7 0,000 6,161E-03 0,02594499 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 7 0,000 6,161E-03 0,02591443 ! SMAD protein nuclear translocation GO:0007184 8 7 0,000 6,161E-03 0,02588395 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 7 7 0,000 6,161E-03 0,02585353 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 6,161E-03 0,02582319 ! diphosphotransferase activity GO:0016778 8 7 0,000 6,161E-03 0,02579291 ! actin-myosin filament sliding GO:0033275 7 7 0,000 6,161E-03 0,02576271 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! signal peptide processing GO:0006465 7 7 0,000 6,161E-03 0,02573258 ! glycine hydroxymethyltransferase activity GO:0004372 8 7 0,000 6,161E-03 0,02570252 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 6,161E-03 0,02567252 ! macrophage chemotaxis GO:0048246 7 7 0,000 6,161E-03 0,0256426 ! cerebral cortex cell migration GO:0021795 7 7 0,000 6,161E-03 0,02561275 ! tachykinin receptor signaling pathway GO:0007217 7 7 0,000 6,161E-03 0,02558297 ! membrane hyperpolarization GO:0060081 7 7 0,000 6,161E-03 0,02555326 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 6,161E-03 0,02552361 ! enoyl-CoA hydratase activity GO:0004300 7 7 0,000 6,161E-03 0,02549404 ! DNA replication origin binding GO:0003688 7 7 0,000 6,161E-03 0,02546453 ! ATPase binding GO:0051117 7 7 0,000 6,161E-03 0,02543509 ! positive regulation of glycolysis GO:0045821 7 7 0,000 6,161E-03 0,02540572 ! positive regulation of isotype switching GO:0045830 11 7 0,000 6,161E-03 0,02537642 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 8 7 0,000 6,161E-03 0,02534718 ! ribonucleoside triphosphate catabolic process GO:0009203 7 7 0,000 6,161E-03 0,02531801 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! protein-cofactor linkage GO:0018065 7 7 0,000 6,161E-03 0,02528891 ! positive regulation of chemokine biosynthetic process GO:0045080 7 7 0,000 6,161E-03 0,02525988 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 7 7 0,000 6,161E-03 0,02523091 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! thymic T cell selection GO:0045061 11 7 0,000 6,161E-03 0,02520201 ! structural constituent of tooth enamel GO:0030345 7 7 0,000 6,161E-03 0,02517317 ! transepithelial chloride transport GO:0030321 7 7 0,000 6,161E-03 0,0251444 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 6,161E-03 0,0251157 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 6,161E-03 0,02508706 ! glycine catabolic process GO:0006546 7 7 0,000 6,161E-03 0,02505849 GO:0009071|serine family amino acid catabolic process, ! deoxyribonucleotide biosynthetic process GO:0009263 8 7 0,000 6,161E-03 0,02502998 ! cytoskeletal anchoring at plasma membrane GO:0007016 8 7 0,000 6,161E-03 0,02500154 ! response to pH GO:0009268 7 7 0,000 6,161E-03 0,02497316 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 6,161E-03 0,02494485 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! polyamine biosynthetic process GO:0006596 7 7 0,000 6,161E-03 0,0249166 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 7 7 0,000 6,161E-03 0,02488841 ! endosome organization GO:0007032 7 7 0,000 6,161E-03 0,02486029 ! thyroid hormone generation GO:0006590 7 7 0,000 6,161E-03 0,02483223 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 6,161E-03 0,02480423 GO:0021940|positive regulation of granule cell precursor proliferation, ! reverse cholesterol transport GO:0043691 7 7 0,000 6,161E-03 0,0247763 ! tumor necrosis factor receptor activity GO:0005031 7 7 0,000 6,161E-03 0,02474843 ! indolalkylamine metabolic process GO:0006586 7 7 0,000 6,161E-03 0,02472062 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! proton-transporting V-type ATPase, V1 domain GO:0033180 7 7 0,000 6,161E-03 0,02469288 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 6,161E-03 0,02466519 ! retinoid X receptor binding GO:0046965 7 7 0,000 6,161E-03 0,02463757 ! central nervous system neuron axonogenesis GO:0021955 7 7 0,000 6,161E-03 0,02461002 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 6,161E-03 0,02458252 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! regulation of phosphoprotein phosphatase activity GO:0043666 7 7 0,000 6,161E-03 0,02455508 GO:0010921|regulation of phosphatase activity, ! platelet-derived growth factor receptor activity GO:0005017 7 7 0,000 6,161E-03 0,02452771 ! urea metabolic process GO:0019627 7 7 0,000 6,161E-03 0,02450039 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! retinoic acid receptor signaling pathway GO:0048384 7 7 0,000 6,161E-03 0,02447314 ! regulation of type I interferon production GO:0032479 8 7 0,000 6,161E-03 0,02444595 ! peroxisomal matrix GO:0005782 7 7 0,000 6,161E-03 0,02441882 GO:0031907|microbody lumen, ! methyltransferase complex GO:0034708 7 7 0,000 6,161E-03 0,02439174 GO:0035097|histone methyltransferase complex, ! response to dietary excess GO:0002021 7 7 0,000 6,161E-03 0,02436473 ! p53 binding GO:0002039 7 7 0,000 6,161E-03 0,02433778 ! osteoblast development GO:0002076 8 7 0,000 6,161E-03 0,02431089 ! positive regulation of nitric-oxide synthase activity GO:0051000 7 7 0,000 6,161E-03 0,02428405 ! lipid phosphatase activity GO:0042577 7 7 0,000 6,161E-03 0,02425728 ! male sex determination GO:0030238 7 7 0,000 6,161E-03 0,02423057 ! clathrin binding GO:0030276 8 7 0,000 6,161E-03 0,02420391 ! negative regulation of translational initiation GO:0045947 7 7 0,000 6,161E-03 0,02417731 ! determination of anterior/posterior axis, embryo GO:0008595 7 7 0,000 6,161E-03 0,02415077 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 7 7 0,000 6,161E-03 0,02412429 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 6,161E-03 0,02409787 GO:0030204|chondroitin sulfate metabolic process, ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 6,161E-03 0,0240715 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 6,161E-03 0,0240452 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 6,161E-03 0,02401895 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 6,161E-03 0,02399275 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 8 7 0,000 6,161E-03 0,02396662 ! hyaluronan metabolic process GO:0030212 8 7 0,000 6,161E-03 0,02394054 ! protein retention in ER lumen GO:0006621 7 7 0,000 6,161E-03 0,02391452 ! cardiac muscle cell differentiation GO:0055007 7 7 0,000 6,161E-03 0,02388855 ! peptidyl-arginine modification GO:0018195 7 7 0,000 6,161E-03 0,02386264 ! regulation of circadian rhythm GO:0042752 7 7 0,000 6,161E-03 0,02383679 ! Hsp90 protein binding GO:0051879 7 7 0,000 6,161E-03 0,02381099 ! MutSalpha complex binding GO:0032407 8 7 0,000 6,161E-03 0,02378525 ! regulation of fat cell differentiation GO:0045598 7 7 0,000 6,161E-03 0,02375956 ! establishment of melanosome localization GO:0032401 7 7 0,000 6,161E-03 0,02373393 ! regulation of focal adhesion formation GO:0051893 9 7 0,000 6,161E-03 0,02370836 ! gas homeostasis GO:0033483 7 7 0,000 6,161E-03 0,02368284 ! cranial nerve morphogenesis GO:0021602 7 7 0,000 6,161E-03 0,02365737 ! subpallium development GO:0021544 7 7 0,000 6,161E-03 0,02363196 ! laminin-1 complex GO:0005606 7 7 0,000 6,161E-03 0,0236066 GO:0043256|laminin complex, ! molybdopterin cofactor biosynthetic process GO:0032324 7 7 0,000 6,161E-03 0,0235813 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 8 7 0,000 6,161E-03 0,02355605 ! eye photoreceptor cell differentiation GO:0001754 10 7 0,000 6,161E-03 0,02353086 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 7 7 0,000 6,161E-03 0,02350572 ! positive regulation of immunoglobulin mediated immune response GO:0002891 11 7 0,000 6,161E-03 0,02348063 GO:0002714|positive regulation of B cell mediated immunity, ! protein sumoylation GO:0016925 7 7 0,000 6,161E-03 0,0234556 ! establishment of chromosome localization GO:0051303 7 7 0,000 6,161E-03 0,02343062 GO:0050000|chromosome localization, ! regulation of lipid transport GO:0032368 7 7 0,000 6,161E-03 0,0234057 ! regulation of cell division GO:0051302 7 7 0,000 6,161E-03 0,02338082 ! chromatin assembly complex GO:0005678 7 7 0,000 6,161E-03 0,023356 ! sex chromatin GO:0001739 7 7 0,000 6,161E-03 0,02333123 GO:0000803|sex chromosome, ! oligosaccharyl transferase activity GO:0004576 7 7 0,000 6,161E-03 0,02330652 ! chitinase activity GO:0004568 7 7 0,000 6,161E-03 0,02328186 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 7 7 0,000 6,161E-03 0,02325725 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 7 7 0,000 6,161E-03 0,02323269 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 10 7 0,000 6,161E-03 0,02320818 ! inhibitory MHC class I receptor activity GO:0032396 7 7 0,000 6,161E-03 0,02318372 GO:0030110|HLA-C specific inhibitory MHC class I receptor activity, ! ER to Golgi transport vesicle GO:0030134 7 7 0,000 6,161E-03 0,02315932 ! molybdenum ion binding GO:0030151 7 7 0,000 6,161E-03 0,02313497 ! centriolar satellite GO:0034451 8 7 0,000 6,161E-03 0,02311067 ! positive regulation of epidermis development GO:0045684 7 7 0,000 6,161E-03 0,02308642 ! proteasome regulator activity GO:0010860 7 7 0,000 6,161E-03 0,02306222 ! antibiotic transport GO:0042891 7 7 0,000 6,161E-03 0,02303807 ! negative regulation of transmission of nerve impulse GO:0051970 8 7 0,000 6,161E-03 0,02301397 ! regulation of synaptic transmission, glutamatergic GO:0051966 7 7 0,000 6,161E-03 0,02298992 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 6,161E-03 0,02296592 ! aspartate family amino acid catabolic process GO:0009068 7 7 0,000 6,161E-03 0,02294197 ! Wnt receptor activity GO:0042813 7 7 0,000 6,161E-03 0,02291808 ! regulation of protein homodimerization activity GO:0043496 7 7 0,000 6,161E-03 0,02289423 ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 7 7 0,000 6,161E-03 0,02287043 ! negative regulation of viral reproduction GO:0048525 7 7 0,000 6,161E-03 0,02284668 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 9 7 0,000 6,161E-03 0,02282298 ! blastocyst growth GO:0001832 7 7 0,000 6,161E-03 0,02279933 ! pigment granule transport GO:0051904 7 7 0,000 6,161E-03 0,02277573 ! lymphocyte activation during immune response GO:0002285 7 7 0,000 6,161E-03 0,02275218 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 6,161E-03 0,02272867 ! negative regulation of fibrinolysis GO:0051918 7 7 0,000 6,161E-03 0,02270522 ! negative regulation of telomere maintenance GO:0032205 7 7 0,000 6,161E-03 0,02268181 ! cerebellar cortex formation GO:0021697 8 7 0,000 6,161E-03 0,02265845 ! activation of innate immune response GO:0002218 7 7 0,000 6,161E-03 0,02263514 GO:0002758|innate immune response-activating signal transduction, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 7 7 0,000 6,161E-03 0,02261187 ! natural killer cell mediated immunity GO:0002228 7 7 0,000 6,161E-03 0,02258866 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of synaptic transmission, dopaminergic GO:0032225 7 7 0,000 6,161E-03 0,02256549 ! regulation of synaptic transmission, GABAergic GO:0032228 7 7 0,000 6,161E-03 0,02254237 ! flavin-containing monooxygenase activity GO:0004499 7 7 0,000 6,161E-03 0,0225193 ! regulation of muscle adaptation GO:0043502 7 7 0,000 6,161E-03 0,02249627 ! sequestering of metal ion GO:0051238 7 7 0,000 6,161E-03 0,02247329 ! regulation of T cell receptor signaling pathway GO:0050856 8 7 0,000 6,161E-03 0,02245036 ! membrane attack complex GO:0005579 7 7 0,000 6,161E-03 0,02242748 ! fibrinogen complex GO:0005577 7 7 0,000 6,161E-03 0,02240464 ! septin complex GO:0031105 9 7 0,000 6,161E-03 0,02238185 GO:0032156|septin cytoskeleton, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 7 7 0,000 6,161E-03 0,0223591 ! positive regulation of microtubule polymerization GO:0031116 7 7 0,000 6,161E-03 0,0223364 ! cellular anion homeostasis GO:0030002 7 7 0,000 6,161E-03 0,02231375 GO:0055081|anion homeostasis, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 7 7 0,000 6,161E-03 0,02229114 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! behavioral response to cocaine GO:0048148 9 7 0,000 6,161E-03 0,02226858 ! autophagic vacuole formation GO:0000045 8 7 0,000 6,161E-03 0,02224606 ! negative regulation of smooth muscle cell proliferation GO:0048662 7 7 0,000 6,161E-03 0,02222359 ! translation initiation factor binding GO:0031369 7 7 0,000 6,161E-03 0,02220116 ! regulation of lipid catabolic process GO:0050994 7 7 0,000 6,161E-03 0,02217878 ! activin binding GO:0048185 7 7 0,000 6,161E-03 0,02215645 ! syncytium formation by plasma membrane fusion GO:0000768 7 7 0,000 6,161E-03 0,02213416 GO:0007520|myoblast fusion, ! nucleotide-excision repair, DNA incision GO:0033683 7 7 0,000 6,161E-03 0,02211191 ! oligosaccharyltransferase complex GO:0008250 7 7 0,000 6,161E-03 0,02208971 ! phototransduction, visible light GO:0007603 7 7 0,000 6,161E-03 0,02206756 ! positive regulation of neurotransmitter transport GO:0051590 7 7 0,000 6,161E-03 0,02204544 ! lipoprotein transport GO:0042953 7 7 0,000 6,161E-03 0,02202338 ! cell division site part GO:0032155 7 7 0,000 6,161E-03 0,02200135 GO:0032153|cell division site, ! laminin binding GO:0043236 9 7 0,000 6,161E-03 0,02197937 ! detection of mechanical stimulus involved in sensory perception GO:0050974 7 7 0,000 6,161E-03 0,02195744 ! phospholipid efflux GO:0033700 7 7 0,000 6,161E-03 0,02193555 ! DNA insertion or deletion binding GO:0032135 7 7 0,000 6,161E-03 0,0219137 GO:0032138|single base insertion or deletion binding, ! glucocorticoid metabolic process GO:0008211 7 7 0,000 6,161E-03 0,02189189 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 7 7 0,000 6,161E-03 0,02187013 ! poly-purine tract binding GO:0070717 7 7 0,000 6,161E-03 0,02184841 ! T-helper 1 type immune response GO:0042088 7 7 0,000 6,161E-03 0,02182674 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 6,161E-03 0,02180511 GO:0032107|regulation of response to nutrient levels, ! amyloid precursor protein catabolic process GO:0042987 7 7 0,000 6,161E-03 0,02178352 ! leukocyte degranulation GO:0043299 7 7 0,000 6,161E-03 0,02176197 ! sodium:phosphate symporter activity GO:0005436 7 7 0,000 6,161E-03 0,02174047 ! bile acid and bile salt transport GO:0015721 7 7 0,000 6,161E-03 0,02171901 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 6,161E-03 0,02169759 ! glycerol ether biosynthetic process GO:0046504 7 7 0,000 6,161E-03 0,02167621 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 6,161E-03 0,02165488 GO:0046513|ceramide biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 6,161E-03 0,02163358 ! pigment granule organization GO:0048753 7 7 0,000 6,161E-03 0,02161233 ! eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 7 7 0,000 6,161E-03 0,02159112 ! regulation of interleukin-8 biosynthetic process GO:0045414 8 7 0,000 6,161E-03 0,02156995 ! regulation of pigmentation during development GO:0048070 10 7 0,000 6,161E-03 0,02154883 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 7 7 0,000 6,161E-03 0,02152774 ! macrophage activation GO:0042116 7 7 0,000 6,161E-03 0,0215067 ! positive regulation of activated T cell proliferation GO:0042104 7 7 0,000 6,161E-03 0,0214857 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 7 7 0,000 6,161E-03 0,02146474 ! galactose metabolic process GO:0006012 7 7 0,000 6,161E-03 0,02144381 ! vesicle fusion GO:0006906 7 7 0,000 6,161E-03 0,02142293 ! positive regulation of insulin secretion GO:0032024 7 7 0,000 6,161E-03 0,0214021 ! glycerol ether catabolic process GO:0044269 7 7 0,000 6,161E-03 0,0213813 GO:0046464|acylglycerol catabolic process, ! virus-infected cell apoptosis GO:0006926 7 7 0,000 6,161E-03 0,02136054 ! NuA4 histone acetyltransferase complex GO:0035267 8 7 0,000 6,161E-03 0,02133982 ! nucleoside transmembrane transporter activity GO:0005337 7 7 0,000 6,161E-03 0,02131914 GO:0015858|nucleoside transport, ! regulation of vascular permeability GO:0043114 7 7 0,000 6,161E-03 0,0212985 ! regulation of multicellular organismal metabolic process GO:0044246 8 7 0,000 6,161E-03 0,02127791 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 6,161E-03 0,02125735 ! peptidyl-proline dioxygenase activity GO:0031543 7 7 0,000 6,161E-03 0,02123683 ! inclusion body GO:0016234 7 7 0,000 6,161E-03 0,02121635 ! parturition GO:0007567 7 7 0,000 6,161E-03 0,02119591 ! tRNA methyltransferase activity GO:0008175 7 7 0,000 6,161E-03 0,02117551 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 7 7 0,000 6,161E-03 0,02115515 ! intercalated disc GO:0014704 8 7 0,000 6,161E-03 0,02113483 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 6,161E-03 0,02111454 ! neural nucleus development GO:0048857 7 7 0,000 6,161E-03 0,0210943 ! intermediate filament organization GO:0045109 8 7 0,000 6,161E-03 0,02107409 ! skeletal muscle contraction GO:0003009 7 7 0,000 6,161E-03 0,02105393 ! response to antibiotic GO:0046677 7 7 0,000 6,161E-03 0,0210338 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 7 7 0,000 6,161E-03 0,02101371 ! preribosome GO:0030684 7 7 0,000 6,161E-03 0,02099366 ! positive regulation of production of molecular mediator of immune response GO:0002702 7 7 0,000 6,161E-03 0,02097365 ! hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 7 7 0,000 6,161E-03 0,02095367 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 7 7 0,000 6,161E-03 0,02093373 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 6,161E-03 0,02091383 ! regulation of interleukin-1 production GO:0032652 7 7 0,000 6,161E-03 0,02089397 ! phosphofructokinase activity GO:0008443 7 7 0,000 6,161E-03 0,02087415 ! gap junction channel activity GO:0005243 7 7 0,000 6,161E-03 0,02085436 ! mitochondrion morphogenesis GO:0070584 8 7 0,000 6,161E-03 0,02083462 ! transcription termination GO:0006353 8 7 0,000 6,161E-03 0,0208149 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 7 7 0,000 6,161E-03 0,02079523 ! tetracycline transporter activity GO:0008493 7 7 0,000 6,161E-03 0,02077559 GO:0042895|antibiotic transporter activity, ! cytidylyltransferase activity GO:0070567 7 7 0,000 6,161E-03 0,02075599 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 6,161E-03 0,02073643 ! melanocortin receptor activity GO:0004977 7 7 0,000 6,161E-03 0,02071691 ! coenzyme A metabolic process GO:0015936 8 7 0,000 6,161E-03 0,02069742 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 7 0,000 6,161E-03 0,02067796 ! regulation of macrophage activation GO:0043030 7 7 0,000 6,161E-03 0,02065855 ! cytidine deaminase activity GO:0004126 7 7 0,000 6,161E-03 0,02063917 ! inositol trisphosphate kinase activity GO:0051766 7 7 0,000 6,161E-03 0,02061983 ! apical protein localization GO:0045176 7 7 0,000 6,161E-03 0,02060052 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 6,161E-03 0,02058125 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 6,161E-03 0,02056201 ! virion binding GO:0046790 10 7 0,000 6,161E-03 0,02054281 ! nonprotein amino acid metabolic process GO:0019794 7 7 0,000 6,161E-03 0,02052365 ! protein prenyltransferase activity GO:0008318 7 7 0,000 6,161E-03 0,02050452 ! protein modification by small protein removal GO:0070646 7 7 0,000 6,161E-03 0,02048543 ! adult feeding behavior GO:0008343 7 7 0,000 6,161E-03 0,02046638 ! CoA carboxylase activity GO:0016421 7 7 0,000 6,161E-03 0,02044735 ! microtubule basal body GO:0005932 7 7 0,000 6,161E-03 0,02042837 ! positive regulation of NF-kappaB import into nucleus GO:0042346 7 7 0,000 6,161E-03 0,02040942 ! embryonic heart tube development GO:0035050 7 7 0,000 6,161E-03 0,0203905 ! kainate selective glutamate receptor activity GO:0015277 7 7 0,000 6,161E-03 0,02037162 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 6,161E-03 0,02035278 ! positive regulation of smooth muscle contraction GO:0045987 7 7 0,000 6,161E-03 0,02033397 ! rRNA transcription GO:0009303 8 8 0,000 7,038E-03 0,02320791 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 8 8 0,000 7,038E-03 0,0231865 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 7,038E-03 0,02316513 ! sodium:hydrogen antiporter activity GO:0015385 8 8 0,000 7,038E-03 0,0231438 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cation:chloride symporter activity GO:0015377 9 8 0,000 7,038E-03 0,02312251 ! positive regulation of small GTPase mediated signal transduction GO:0051057 8 8 0,000 7,038E-03 0,02310126 GO:0046579|positive regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 8 0,000 7,038E-03 0,02308005 ! male meiosis GO:0007140 8 8 0,000 7,038E-03 0,02305887 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8 8 0,000 7,038E-03 0,02303774 ! N-glycan processing GO:0006491 8 8 0,000 7,038E-03 0,02301664 ! regulation of smooth muscle cell migration GO:0014910 9 8 0,000 7,038E-03 0,02299558 ! protein self-association GO:0043621 8 8 0,000 7,038E-03 0,02297456 ! RNA methylation GO:0001510 8 8 0,000 7,038E-03 0,02295358 ! prostaglandin biosynthetic process GO:0001516 9 8 0,000 7,038E-03 0,02293264 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 8 8 0,000 7,038E-03 0,02291173 ! regulation of activated T cell proliferation GO:0046006 8 8 0,000 7,038E-03 0,02289087 ! hexokinase activity GO:0004396 8 8 0,000 7,038E-03 0,02287004 ! neurofilament cytoskeleton GO:0060053 8 8 0,000 7,038E-03 0,02284925 ! guanylate cyclase activity GO:0004383 8 8 0,000 7,038E-03 0,02282849 ! integral to mitochondrial membrane GO:0032592 8 8 0,000 7,038E-03 0,02280778 ! troponin complex GO:0005861 9 8 0,000 7,038E-03 0,0227871 ! smoothened signaling pathway GO:0007224 8 8 0,000 7,038E-03 0,02276646 ! keratinocyte proliferation GO:0043616 8 8 0,000 7,038E-03 0,02274586 ! negative regulation of muscle cell differentiation GO:0051148 8 8 0,000 7,038E-03 0,02272529 ! ganglioside metabolic process GO:0001573 8 8 0,000 7,038E-03 0,02270476 ! reflex GO:0060004 11 8 0,000 7,038E-03 0,02268427 ! small protein activating enzyme activity GO:0008641 10 8 0,000 7,038E-03 0,02266381 ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 7,038E-03 0,0226434 ! hemoglobin metabolic process GO:0020027 8 8 0,000 7,038E-03 0,02262302 ! protein targeting to ER GO:0045047 9 8 0,000 7,038E-03 0,02260267 ! positive regulation of survival gene product expression GO:0045885 8 8 0,000 7,038E-03 0,02258236 ! arginine catabolic process GO:0006527 8 8 0,000 7,038E-03 0,02256209 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 7,038E-03 0,02254186 ! malate dehydrogenase activity GO:0016615 8 8 0,000 7,038E-03 0,02252166 ! inner mitochondrial membrane organization GO:0007007 9 8 0,000 7,038E-03 0,02250149 ! telomere maintenance via telomerase GO:0007004 8 8 0,000 7,038E-03 0,02248137 GO:0010833|telomere maintenance via telomere lengthening, ! DNA secondary structure binding GO:0000217 8 8 0,000 7,038E-03 0,02246128 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 9 8 0,000 7,038E-03 0,02244122 ! proline metabolic process GO:0006560 9 8 0,000 7,038E-03 0,0224212 ! melanosome membrane GO:0033162 10 8 0,000 7,038E-03 0,02240122 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 7,038E-03 0,02238127 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 7,038E-03 0,02236136 ! melanin metabolic process GO:0006582 9 8 0,000 7,038E-03 0,02234148 ! death receptor activity GO:0005035 8 8 0,000 7,038E-03 0,02232164 ! Golgi lumen GO:0005796 8 8 0,000 7,038E-03 0,02230184 ! smooth endoplasmic reticulum GO:0005790 9 8 0,000 7,038E-03 0,02228207 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 7,038E-03 0,02226233 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 9 8 0,000 7,038E-03 0,02224263 GO:0048500|signal recognition particle, ! Golgi cisterna GO:0031985 9 8 0,000 7,038E-03 0,02222296 ! positive regulation of mesenchymal cell proliferation GO:0002053 8 8 0,000 7,038E-03 0,02220333 ! Rac protein signal transduction GO:0016601 8 8 0,000 7,038E-03 0,02218373 ! positive regulation of calcium ion transport into cytosol GO:0010524 11 8 0,000 7,038E-03 0,02216417 ! lens development in camera-type eye GO:0002088 8 8 0,000 7,038E-03 0,02214464 ! positive regulation of vasodilation GO:0045909 8 8 0,000 7,038E-03 0,02212515 ! intestinal cholesterol absorption GO:0030299 8 8 0,000 7,038E-03 0,02210569 ! negative regulation of muscle contraction GO:0045932 9 8 0,000 7,038E-03 0,02208627 ! positive regulation vascular endothelial growth factor production GO:0010575 8 8 0,000 7,038E-03 0,02206687 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 8 8 0,000 7,038E-03 0,02204752 ! Schwann cell differentiation GO:0014037 8 8 0,000 7,038E-03 0,02202819 ! sodium:dicarboxylate symporter activity GO:0017153 8 8 0,000 7,038E-03 0,02200891 ! axon guidance receptor activity GO:0008046 8 8 0,000 7,038E-03 0,02198965 ! protein targeting to vacuole GO:0006623 8 8 0,000 7,038E-03 0,02197043 ! response to tropane GO:0014073 10 8 0,000 7,038E-03 0,02195124 GO:0042220|response to cocaine, ! purine nucleoside triphosphate catabolic process GO:0009146 8 8 0,000 7,038E-03 0,02193209 ! melanosome localization GO:0032400 8 8 0,000 7,038E-03 0,02191296 ! response to amine stimulus GO:0014075 10 8 0,000 7,038E-03 0,02189388 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 8 8 0,000 7,038E-03 0,02187482 ! sphingomyelin metabolic process GO:0006684 9 8 0,000 7,038E-03 0,0218558 ! regulation of mitochondrial membrane potential GO:0051881 8 8 0,000 7,038E-03 0,02183681 ! synaptic vesicle endocytosis GO:0048488 8 8 0,000 7,038E-03 0,02181786 ! holo TFIIH complex GO:0005675 8 8 0,000 7,038E-03 0,02179893 ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 7,038E-03 0,02178004 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 8 0,000 7,038E-03 0,02176119 ! negative regulation of cytokine secretion GO:0050710 8 8 0,000 7,038E-03 0,02174236 ! regulation of myoblast differentiation GO:0045661 8 8 0,000 7,038E-03 0,02172357 ! vitamin transporter activity GO:0051183 8 8 0,000 7,038E-03 0,02170481 ! positive regulation of erythrocyte differentiation GO:0045648 8 8 0,000 7,038E-03 0,02168608 ! neuromuscular process controlling posture GO:0050884 8 8 0,000 7,038E-03 0,02166739 ! heparan sulfate sulfotransferase activity GO:0034483 8 8 0,000 7,038E-03 0,02164873 ! regulation of epidermal cell differentiation GO:0045604 8 8 0,000 7,038E-03 0,02163009 ! regulation of T-helper 2 cell differentiation GO:0045628 8 8 0,000 7,038E-03 0,0216115 ! positive regulation of T-helper cell differentiation GO:0045624 8 8 0,000 7,038E-03 0,02159293 ! branched chain family amino acid catabolic process GO:0009083 8 8 0,000 7,038E-03 0,02157439 ! regulation of synaptogenesis GO:0051963 8 8 0,000 7,038E-03 0,02155589 ! oocyte differentiation GO:0009994 8 8 0,000 7,038E-03 0,02153742 GO:0048599|oocyte development, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 8 8 0,000 7,038E-03 0,02151898 GO:0003756|protein disulfide isomerase activity, ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 7,038E-03 0,02150057 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 8 0,000 7,038E-03 0,0214822 ! beta-1,3-galactosyltransferase activity GO:0048531 8 8 0,000 7,038E-03 0,02146385 ! establishment of pigment granule localization GO:0051905 8 8 0,000 7,038E-03 0,02144554 ! regulation of telomere maintenance GO:0032204 8 8 0,000 7,038E-03 0,02142725 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 7,038E-03 0,021409 ! amino sugar catabolic process GO:0046348 8 8 0,000 7,038E-03 0,02139078 GO:0006043|glucosamine catabolic process, ! regulation of amino acid transport GO:0051955 8 8 0,000 7,038E-03 0,02137259 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 7,038E-03 0,02135443 ! T cell receptor signaling pathway GO:0050852 13 8 0,000 7,038E-03 0,02133631 ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 8 0,000 7,038E-03 0,02131821 ! cholesterol transporter activity GO:0017127 8 8 0,000 7,038E-03 0,02130014 ! GABA receptor binding GO:0050811 8 8 0,000 7,038E-03 0,02128211 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 8 8 0,000 7,038E-03 0,0212641 ! regulation of microtubule polymerization GO:0031113 8 8 0,000 7,038E-03 0,02124613 ! regulation of developmental growth GO:0048638 8 8 0,000 7,038E-03 0,02122818 ! GMP binding GO:0019002 10 8 0,000 7,038E-03 0,02121027 GO:0030553|cGMP binding, ! regulation of epithelial cell differentiation GO:0030856 8 8 0,000 7,038E-03 0,02119239 ! negative regulation of cellular catabolic process GO:0031330 9 8 0,000 7,038E-03 0,02117453 ! prostate gland development GO:0030850 8 8 0,000 7,038E-03 0,02115671 ! 7S RNA binding GO:0008312 9 8 0,000 7,038E-03 0,02113891 ! phosphate transport GO:0006817 9 8 0,000 7,038E-03 0,02112115 ! neutral lipid catabolic process GO:0046461 8 8 0,000 7,038E-03 0,02110342 ! protein phosphorylated amino acid binding GO:0045309 10 8 0,000 7,038E-03 0,02108571 ! reproductive behavior GO:0019098 8 8 0,000 7,038E-03 0,02106804 ! cell volume homeostasis GO:0006884 9 8 0,000 7,038E-03 0,02105039 ! regulation of long-term neuronal synaptic plasticity GO:0048169 8 8 0,000 7,038E-03 0,02103278 ! oligopeptide transport GO:0006857 8 8 0,000 7,038E-03 0,02101519 GO:0015198|oligopeptide transporter activity, ! induction of positive chemotaxis GO:0050930 8 8 0,000 7,038E-03 0,02099764 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 7,038E-03 0,02098011 ! regulation of dopamine metabolic process GO:0042053 8 8 0,000 7,038E-03 0,02096261 GO:0042069|regulation of catecholamine metabolic process, ! regulation of carbohydrate biosynthetic process GO:0043255 8 8 0,000 7,038E-03 0,02094514 ! titin binding GO:0031432 8 8 0,000 7,038E-03 0,0209277 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 7,038E-03 0,02091029 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 8 0,000 7,038E-03 0,02089291 ! bone resorption GO:0045453 8 8 0,000 7,038E-03 0,02087556 ! glycerolipid catabolic process GO:0046503 8 8 0,000 7,038E-03 0,02085823 ! endoderm development GO:0007492 8 8 0,000 7,038E-03 0,02084094 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 7,038E-03 0,02082367 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 7,038E-03 0,02080643 ! astrocyte differentiation GO:0048708 8 8 0,000 7,038E-03 0,02078922 ! embryonic cranial skeleton morphogenesis GO:0048701 8 8 0,000 7,038E-03 0,02077204 ! syncytium formation GO:0006949 8 8 0,000 7,038E-03 0,02075489 ! embryonic eye morphogenesis GO:0048048 10 8 0,000 7,038E-03 0,02073776 ! B cell proliferation GO:0042100 8 8 0,000 7,038E-03 0,02072067 ! mannose metabolic process GO:0006013 10 8 0,000 7,038E-03 0,0207036 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 8 8 0,000 7,038E-03 0,02068656 ! asymmetric protein localization GO:0008105 8 8 0,000 7,038E-03 0,02066955 ! tumor necrosis factor binding GO:0043120 8 8 0,000 7,038E-03 0,02065256 ! synaptic transmission, glutamatergic GO:0035249 9 8 0,000 7,038E-03 0,02063561 ! neuron apoptosis GO:0051402 8 8 0,000 7,038E-03 0,02061868 ! macroautophagy GO:0016236 9 8 0,000 7,038E-03 0,02060178 ! Cajal body GO:0015030 8 8 0,000 7,038E-03 0,02058491 ! O-methyltransferase activity GO:0008171 9 8 0,000 7,038E-03 0,02056806 ! H4/H2A histone acetyltransferase complex GO:0043189 9 8 0,000 7,038E-03 0,02055124 ! PcG protein complex GO:0031519 8 8 0,000 7,038E-03 0,02053445 ! ferric iron binding GO:0008199 9 8 0,000 7,038E-03 0,02051769 ! spindle checkpoint GO:0031577 8 8 0,000 7,038E-03 0,02050095 ! G1 DNA damage checkpoint GO:0031571 8 8 0,000 7,038E-03 0,02048425 ! segment specification GO:0007379 8 8 0,000 7,038E-03 0,02046757 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 7,038E-03 0,02045091 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 7,038E-03 0,02043428 ! cellular extravasation GO:0045123 9 8 0,000 7,038E-03 0,02041768 ! pronucleus GO:0045120 8 8 0,000 7,038E-03 0,02040111 ! regulation of insulin receptor signaling pathway GO:0046626 8 8 0,000 7,038E-03 0,02038457 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 8 8 0,000 7,038E-03 0,02036805 ! Rac GTPase activator activity GO:0030675 9 8 0,000 7,038E-03 0,02035155 ! transcription-coupled nucleotide-excision repair GO:0006283 9 8 0,000 7,038E-03 0,02033509 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 7,038E-03 0,02031865 ! antigen processing and presentation of exogenous antigen GO:0019884 9 8 0,000 7,038E-03 0,02030224 ! regulation of T cell differentiation in the thymus GO:0033081 8 8 0,000 7,038E-03 0,02028585 ! negative regulation of systemic arterial blood pressure GO:0003085 8 8 0,000 7,038E-03 0,02026949 ! multicellular organismal aging GO:0010259 8 8 0,000 7,038E-03 0,02025316 ! erythrocyte development GO:0048821 8 8 0,000 7,038E-03 0,02023685 ! interleukin-1 receptor activity GO:0004908 8 8 0,000 7,038E-03 0,02022057 ! positive regulation of monooxygenase activity GO:0032770 8 8 0,000 7,038E-03 0,02020432 ! protein import into peroxisome matrix GO:0016558 8 8 0,000 7,038E-03 0,02018809 ! gamma-tubulin binding GO:0043015 8 8 0,000 7,038E-03 0,02017189 ! ribosome binding GO:0043022 9 8 0,000 7,038E-03 0,02015571 ! NADPH oxidase complex GO:0043020 8 8 0,000 7,038E-03 0,02013956 ! mRNA polyadenylation GO:0006378 8 8 0,000 7,038E-03 0,02012343 ! sodium:amino acid symporter activity GO:0005283 8 8 0,000 7,038E-03 0,02010734 ! adenylyltransferase activity GO:0070566 8 8 0,000 7,038E-03 0,02009126 ! zymogen activation GO:0031638 8 8 0,000 7,038E-03 0,02007522 ! axonal fasciculation GO:0007413 8 8 0,000 7,038E-03 0,02005919 ! T cell homeostasis GO:0043029 9 8 0,000 7,038E-03 0,0200432 ! negative regulation of nuclear division GO:0051784 8 8 0,000 7,038E-03 0,02002723 GO:0045839|negative regulation of mitosis, ! caspase inhibitor activity GO:0043027 8 8 0,000 7,038E-03 0,02001128 ! energy coupled proton transport, against electrochemical gradient GO:0015988 8 8 0,000 7,038E-03 0,01999536 GO:0015991|ATP hydrolysis coupled proton transport, ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 8 8 0,000 7,038E-03 0,01997947 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 7,038E-03 0,0199636 ! thyroid hormone receptor activity GO:0004887 8 8 0,000 7,038E-03 0,01994775 ! wide pore channel activity GO:0022829 8 8 0,000 7,038E-03 0,01993193 ! ligand-regulated transcription factor activity GO:0003706 8 8 0,000 7,038E-03 0,01991614 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 7,038E-03 0,01990037 ! hormone catabolic process GO:0042447 8 8 0,000 7,038E-03 0,01988463 ! positive regulation of ATPase activity GO:0032781 8 8 0,000 7,038E-03 0,01986891 ! biogenic amine catabolic process GO:0042402 11 8 0,000 7,038E-03 0,01985321 ! Notch binding GO:0005112 8 8 0,000 7,038E-03 0,01983755 ! death receptor binding GO:0005123 8 8 0,000 7,038E-03 0,0198219 ! ATPase regulator activity GO:0060590 8 8 0,000 7,038E-03 0,01980628 ! pyrimidine base metabolic process GO:0006206 10 8 0,000 7,038E-03 0,01979068 ! epidermal growth factor receptor binding GO:0005154 9 8 0,000 7,038E-03 0,01977511 ! dihydropyridine-sensitive calcium channel activity GO:0015270 8 8 0,000 7,038E-03 0,01975957 ! calcium-release channel activity GO:0015278 8 8 0,000 7,038E-03 0,01974405 ! tubulin-tyrosine ligase activity GO:0004835 8 8 0,000 7,038E-03 0,01972855 ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 7,038E-03 0,01971307 ! nucleus localization GO:0051647 10 8 0,000 7,038E-03 0,01969763 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 7,038E-03 0,0196822 ! negative regulation of immune effector process GO:0002698 12 8 0,000 7,038E-03 0,0196668 ! C-X-C chemokine receptor activity GO:0016494 8 8 0,000 7,038E-03 0,01965142 ! adenosine deaminase activity GO:0004000 8 8 0,000 7,038E-03 0,01963607 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9 9 0,000 7,915E-03 0,02206435 ! respiratory burst GO:0045730 9 9 0,000 7,915E-03 0,02204714 ! telencephalon cell migration GO:0022029 9 9 0,000 7,915E-03 0,02202996 ! 'de novo' posttranslational protein folding GO:0051084 9 9 0,000 7,915E-03 0,0220128 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 7,915E-03 0,02199567 ! cGMP metabolic process GO:0046068 9 9 0,000 7,915E-03 0,02197856 GO:0006182|cGMP biosynthetic process, ! regulation of epidermal growth factor receptor activity GO:0007176 9 9 0,000 7,915E-03 0,02196149 GO:0010469|regulation of receptor activity, ! inositol trisphosphate phosphatase activity GO:0046030 11 9 0,000 7,915E-03 0,02194444 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! axon part GO:0033267 12 9 0,000 7,915E-03 0,02192741 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9 9 0,000 7,915E-03 0,02191041 ! RNA polyadenylation GO:0043631 9 9 0,000 7,915E-03 0,02189344 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 9 0,000 7,915E-03 0,0218765 ! regulation of receptor-mediated endocytosis GO:0048259 9 9 0,000 7,915E-03 0,02185958 ! artery development GO:0060840 9 9 0,000 7,915E-03 0,02184268 GO:0048844|artery morphogenesis, ! photoreceptor cell development GO:0042461 12 9 0,000 7,915E-03 0,02182582 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 9 9 0,000 7,915E-03 0,02180898 ! middle ear morphogenesis GO:0042474 9 9 0,000 7,915E-03 0,02179216 ! regulation of mesenchymal cell proliferation GO:0010464 9 9 0,000 7,915E-03 0,02177537 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 12 9 0,000 7,915E-03 0,02175861 GO:0046330|positive regulation of JNK cascade, ! positive regulation of heart contraction GO:0045823 10 9 0,000 7,915E-03 0,02174187 ! lung alveolus development GO:0048286 9 9 0,000 7,915E-03 0,02172516 ! ciliary or flagellar motility GO:0001539 9 9 0,000 7,915E-03 0,02170847 ! beta-amyloid binding GO:0001540 10 9 0,000 7,915E-03 0,02169181 ! pathogenesis GO:0009405 9 9 0,000 7,915E-03 0,02167518 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 10 9 0,000 7,915E-03 0,02165857 ! regulated secretory pathway GO:0045055 9 9 0,000 7,915E-03 0,02164199 ! regulation of S phase of mitotic cell cycle GO:0007090 9 9 0,000 7,915E-03 0,02162543 ! estrogen receptor binding GO:0030331 9 9 0,000 7,915E-03 0,02160889 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 10 9 0,000 7,915E-03 0,02159239 ! regulation of defense response to virus by virus GO:0050690 9 9 0,000 7,915E-03 0,0215759 ! histidine metabolic process GO:0006547 9 9 0,000 7,915E-03 0,02155945 GO:0009075|histidine family amino acid metabolic process, ! L-phenylalanine metabolic process GO:0006558 10 9 0,000 7,915E-03 0,02154301 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 9 9 0,000 7,915E-03 0,02152661 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 9 9 0,000 7,915E-03 0,02151022 ! nucleobase biosynthetic process GO:0046112 11 9 0,000 7,915E-03 0,02149387 ! regulation of Cdc42 protein signal transduction GO:0032489 9 9 0,000 7,915E-03 0,02147753 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of calcium ion transport into cytosol GO:0010522 12 9 0,000 7,915E-03 0,02146122 ! entry into host cell GO:0030260 9 9 0,000 7,915E-03 0,02144494 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 9 9 0,000 7,915E-03 0,02142868 ! regulation of lipoprotein lipase activity GO:0051004 9 9 0,000 7,915E-03 0,02141245 ! retinoic acid metabolic process GO:0042573 9 9 0,000 7,915E-03 0,02139624 ! retinol metabolic process GO:0042572 9 9 0,000 7,915E-03 0,02138006 ! behavioral fear response GO:0001662 9 9 0,000 7,915E-03 0,0213639 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 10 9 0,000 7,915E-03 0,02134776 ! regulation of vascular endothelial growth factor production GO:0010574 9 9 0,000 7,915E-03 0,02133165 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9 9 0,000 7,915E-03 0,02131556 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! motor axon guidance GO:0008045 9 9 0,000 7,915E-03 0,0212995 ! regulation of gliogenesis GO:0014013 9 9 0,000 7,915E-03 0,02128346 GO:0045685|regulation of glial cell differentiation, ! recycling endosome membrane GO:0055038 10 9 0,000 7,915E-03 0,02126744 ! pigment granule localization GO:0051875 9 9 0,000 7,915E-03 0,02125145 ! platelet-derived growth factor binding GO:0048407 10 9 0,000 7,915E-03 0,02123549 ! glycosphingolipid biosynthetic process GO:0006688 9 9 0,000 7,915E-03 0,02121954 ! nucleoside diphosphate metabolic process GO:0009132 10 9 0,000 7,915E-03 0,02120363 ! phosphoinositide 3-kinase cascade GO:0014065 9 9 0,000 7,915E-03 0,02118773 ! cell wall macromolecule catabolic process GO:0016998 10 9 0,000 7,915E-03 0,02117186 ! purine ribonucleotide catabolic process GO:0009154 9 9 0,000 7,915E-03 0,02115601 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 9 9 0,000 7,915E-03 0,02114019 ! positive regulation of Rho GTPase activity GO:0032321 9 9 0,000 7,915E-03 0,02112439 ! nitric oxide metabolic process GO:0046209 9 9 0,000 7,915E-03 0,02110861 GO:0006809|nitric oxide biosynthetic process, ! mismatch repair complex GO:0032300 9 9 0,000 7,915E-03 0,02109286 ! icosanoid secretion GO:0032309 9 9 0,000 7,915E-03 0,02107713 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 10 9 0,000 7,915E-03 0,02106143 GO:0010092|specification of organ identity, ! retinal ganglion cell axon guidance GO:0031290 9 9 0,000 7,915E-03 0,02104574 ! morphogenesis of a polarized epithelium GO:0001738 9 9 0,000 7,915E-03 0,02103008 ! sterol catabolic process GO:0016127 9 9 0,000 7,915E-03 0,02101445 GO:0006707|cholesterol catabolic process, ! prophase GO:0051324 9 9 0,000 7,915E-03 0,02099884 ! peptidyl-lysine modification GO:0018205 9 9 0,000 7,915E-03 0,02098325 ! pancreatic ribonuclease activity GO:0004522 9 9 0,000 7,915E-03 0,02096768 ! clathrin coat of coated pit GO:0030132 12 9 0,000 7,915E-03 0,02095214 ! SNARE complex GO:0031201 10 9 0,000 7,915E-03 0,02093662 ! ubiquinone metabolic process GO:0006743 10 9 0,000 7,915E-03 0,02092112 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! snRNA binding GO:0017069 9 9 0,000 7,915E-03 0,02090565 ! regulation of macrophage differentiation GO:0045649 9 9 0,000 7,915E-03 0,02089019 ! regulation of osteoclast differentiation GO:0045670 10 9 0,000 7,915E-03 0,02087477 ! positive regulation of neuron differentiation GO:0045666 9 9 0,000 7,915E-03 0,02085936 ! negative regulation of lymphocyte differentiation GO:0045620 9 9 0,000 7,915E-03 0,02084398 ! methionine biosynthetic process GO:0009086 10 9 0,000 7,915E-03 0,02082862 ! peptidoglycan binding GO:0042834 9 9 0,000 7,915E-03 0,02081328 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 7,915E-03 0,02079796 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! pyridine nucleotide biosynthetic process GO:0019363 9 9 0,000 7,915E-03 0,02078267 ! intramolecular transferase activity, phosphotransferases GO:0016868 9 9 0,000 7,915E-03 0,0207674 ! cholesterol efflux GO:0033344 9 9 0,000 7,915E-03 0,02075215 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 9 9 0,000 7,915E-03 0,02073693 ! metalloenzyme inhibitor activity GO:0048551 10 9 0,000 7,915E-03 0,02072173 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! leukocyte mediated cytotoxicity GO:0001909 9 9 0,000 7,915E-03 0,02070654 ! anterior/posterior axis specification GO:0009948 9 9 0,000 7,915E-03 0,02069139 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 7,915E-03 0,02067625 ! detection of calcium ion GO:0005513 10 9 0,000 7,915E-03 0,02066114 ! negative regulation of glucose import GO:0046325 9 9 0,000 7,915E-03 0,02064604 GO:0010829|negative regulation of glucose transport, ! regulation of fibrinolysis GO:0051917 9 9 0,000 7,915E-03 0,02063097 ! trophectodermal cell differentiation GO:0001829 9 9 0,000 7,915E-03 0,02061592 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 9 0,000 7,915E-03 0,0206009 ! hydrolase activity, acting on ether bonds GO:0016801 9 9 0,000 7,915E-03 0,02058589 ! desmosome GO:0030057 9 9 0,000 7,915E-03 0,02057091 ! prepulse inhibition GO:0060134 9 9 0,000 7,915E-03 0,02055595 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 9 0,000 7,915E-03 0,02054101 ! negative regulation of B cell activation GO:0050869 9 9 0,000 7,915E-03 0,0205261 ! anchoring collagen GO:0030934 9 9 0,000 7,915E-03 0,0205112 ! axon extension GO:0048675 10 9 0,000 7,915E-03 0,02049633 ! neuron fate specification GO:0048665 9 9 0,000 7,915E-03 0,02048147 ! positive regulation of glucose metabolic process GO:0010907 9 9 0,000 7,915E-03 0,02046664 ! cortical actin cytoskeleton organization GO:0030866 9 9 0,000 7,915E-03 0,02045183 ! virus-host interaction GO:0019048 13 9 0,000 7,915E-03 0,02043704 ! rough endoplasmic reticulum membrane GO:0030867 9 9 0,000 7,915E-03 0,02042228 ! pentose-phosphate shunt GO:0006098 9 9 0,000 7,915E-03 0,02040753 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 7,915E-03 0,02039281 ! DNA bending activity GO:0008301 9 9 0,000 7,915E-03 0,02037811 ! social behavior GO:0035176 9 9 0,000 7,915E-03 0,02036342 ! secondary active sulfate transmembrane transporter activity GO:0008271 9 9 0,000 7,915E-03 0,02034876 ! dipeptidyl-peptidase activity GO:0008239 11 9 0,000 7,915E-03 0,02033412 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 7,915E-03 0,02031951 ! very-low-density lipoprotein particle GO:0034361 9 9 0,000 7,915E-03 0,02030491 GO:0034385|triglyceride-rich lipoprotein particle, ! high-density lipoprotein particle GO:0034364 9 9 0,000 7,915E-03 0,02029033 ! amyloid precursor protein metabolic process GO:0042982 10 9 0,000 7,915E-03 0,02027578 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 11 9 0,000 7,915E-03 0,02026124 ! blood vessel remodeling GO:0001974 10 9 0,000 7,915E-03 0,02024673 ! C-X-C chemokine binding GO:0019958 9 9 0,000 7,915E-03 0,02023224 ! 3'-5'-exoribonuclease activity GO:0000175 9 9 0,000 7,915E-03 0,02021776 ! exosome (RNase complex) GO:0000178 9 9 0,000 7,915E-03 0,02020331 ! inositol phosphate-mediated signaling GO:0048016 9 9 0,000 7,915E-03 0,02018888 ! DNA N-glycosylase activity GO:0019104 9 9 0,000 7,915E-03 0,02017447 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 9 9 0,000 7,915E-03 0,02016008 GO:0033549|MAP kinase phosphatase activity, ! ER overload response GO:0006983 11 9 0,000 7,915E-03 0,02014571 ! zinc ion transmembrane transporter activity GO:0005385 9 9 0,000 7,915E-03 0,02013136 ! glucose transmembrane transporter activity GO:0005355 9 9 0,000 7,915E-03 0,02011703 ! retrograde transport, endosome to Golgi GO:0042147 10 9 0,000 7,915E-03 0,02010273 ! phagocytosis, engulfment GO:0006911 10 9 0,000 7,915E-03 0,02008844 ! neurotransmitter biosynthetic process GO:0042136 10 9 0,000 7,915E-03 0,02007417 ! carbohydrate phosphatase activity GO:0019203 9 9 0,000 7,915E-03 0,02005992 ! glutathione peroxidase activity GO:0004602 9 9 0,000 7,915E-03 0,0200457 ! acyl-CoA thioesterase activity GO:0016291 9 9 0,000 7,915E-03 0,02003149 ! lysophospholipase activity GO:0004622 9 9 0,000 7,915E-03 0,0200173 ! brain morphogenesis GO:0048854 9 9 0,000 7,915E-03 0,02000314 ! apolipoprotein binding GO:0034185 9 9 0,000 7,915E-03 0,01998899 ! synaptic vesicle membrane GO:0030672 9 9 0,000 7,915E-03 0,01997486 ! RNA-dependent DNA replication GO:0006278 9 9 0,000 7,915E-03 0,01996076 ! positive regulation of systemic arterial blood pressure GO:0003084 10 9 0,000 7,915E-03 0,01994667 ! kinesin binding GO:0019894 9 9 0,000 7,915E-03 0,0199326 ! nucleoside bisphosphate metabolic process GO:0033865 10 9 0,000 7,915E-03 0,01991856 ! renal water homeostasis GO:0003091 9 9 0,000 7,915E-03 0,01990453 ! positive regulation of interleukin-6 production GO:0032755 9 9 0,000 7,915E-03 0,01989052 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 7,915E-03 0,01987654 ! histone methylation GO:0016571 10 9 0,000 7,915E-03 0,01986257 ! mRNA cleavage GO:0006379 9 9 0,000 7,915E-03 0,01984862 ! negative regulation of tumor necrosis factor production GO:0032720 9 9 0,000 7,915E-03 0,01983469 ! sarcoplasmic reticulum membrane GO:0033017 10 9 0,000 7,915E-03 0,01982078 ! opioid receptor activity GO:0004985 9 9 0,000 7,915E-03 0,01980689 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 7,915E-03 0,01979302 ! salivary gland development GO:0007431 10 9 0,000 7,915E-03 0,01977917 ! glucosidase activity GO:0015926 10 9 0,000 7,915E-03 0,01976534 ! adrenoceptor activity GO:0004935 11 9 0,000 7,915E-03 0,01975153 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 9 9 0,000 7,915E-03 0,01973773 ! positive regulation of leukocyte migration GO:0002687 9 9 0,000 7,915E-03 0,01972396 ! purine base metabolic process GO:0006144 11 9 0,000 7,915E-03 0,0197102 ! mRNA 3'-UTR binding GO:0003730 9 9 0,000 7,915E-03 0,01969647 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 9 9 0,000 7,915E-03 0,01968275 ! receptor inhibitor activity GO:0030547 9 9 0,000 7,915E-03 0,01966906 GO:0048019|receptor antagonist activity, ! negative regulation of BMP signaling pathway GO:0030514 9 9 0,000 7,915E-03 0,01965538 ! ionotropic glutamate receptor complex GO:0008328 11 9 0,000 7,915E-03 0,01964172 ! transforming growth factor beta receptor binding GO:0005160 9 9 0,000 7,915E-03 0,01962808 ! palmitoyltransferase activity GO:0016409 9 9 0,000 7,915E-03 0,01961446 ! arylsulfatase activity GO:0004065 9 9 0,000 7,915E-03 0,01960086 ! phospholipase inhibitor activity GO:0004859 9 9 0,000 7,915E-03 0,01958727 ! behavioral response to nicotine GO:0035095 9 9 0,000 7,915E-03 0,01957371 ! adenylate kinase activity GO:0004017 10 9 0,000 7,915E-03 0,01956016 ! alcohol dehydrogenase (NAD) activity GO:0004022 9 9 0,000 7,915E-03 0,01954663 ! mitochondrion localization GO:0051646 9 9 0,000 7,915E-03 0,01953313 ! localization within membrane GO:0051668 9 9 0,000 7,915E-03 0,01951964 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 10 0,000 8,791E-03 0,0216647 ! lipid particle GO:0005811 10 10 0,000 8,791E-03 0,02164976 ! myotube differentiation GO:0014902 10 10 0,000 8,791E-03 0,02163483 ! generation of neurons in the forebrain GO:0021872 11 10 0,000 8,791E-03 0,02161993 ! regulation of cellular amine metabolic process GO:0033238 10 10 0,000 8,791E-03 0,02160506 ! synapsis GO:0007129 10 10 0,000 8,791E-03 0,0215902 GO:0070192|chromosome organization involved in meiosis, ! filopodium assembly GO:0046847 12 10 0,000 8,791E-03 0,02157536 ! UTP metabolic process GO:0046051 10 10 0,000 8,791E-03 0,02156054 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 10 10 0,000 8,791E-03 0,02154574 ! COPI coating of Golgi vesicle GO:0048205 10 10 0,000 8,791E-03 0,02153096 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 10 10 0,000 8,791E-03 0,02151621 ! platelet alpha granule membrane GO:0031092 11 10 0,000 8,791E-03 0,02150147 ! macromolecule transmembrane transporter activity GO:0022884 10 10 0,000 8,791E-03 0,02148675 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! lipoprotein receptor binding GO:0070325 10 10 0,000 8,791E-03 0,02147206 GO:0050750|low-density lipoprotein receptor binding, ! thyroid hormone receptor coactivator activity GO:0030375 10 10 0,000 8,791E-03 0,02145738 GO:0010861|thyroid hormone receptor activator activity, ! auditory receptor cell differentiation GO:0042491 11 10 0,000 8,791E-03 0,02144272 ! regulation of chemokine biosynthetic process GO:0045073 10 10 0,000 8,791E-03 0,02142809 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 10 10 0,000 8,791E-03 0,02141347 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 8,791E-03 0,02139887 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 10 0,000 8,791E-03 0,0213843 ! nucleotide-sugar metabolic process GO:0009225 11 10 0,000 8,791E-03 0,02136974 ! regulation of catecholamine secretion GO:0050433 10 10 0,000 8,791E-03 0,0213552 ! melanocyte differentiation GO:0030318 10 10 0,000 8,791E-03 0,02134068 GO:0050931|pigment cell differentiation, ! ER-Golgi intermediate compartment membrane GO:0033116 10 10 0,000 8,791E-03 0,02132619 ! deoxyribonucleotide catabolic process GO:0009264 10 10 0,000 8,791E-03 0,02131171 ! L-serine metabolic process GO:0006563 11 10 0,000 8,791E-03 0,02129725 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 10 10 0,000 8,791E-03 0,02128281 ! lipase inhibitor activity GO:0055102 10 10 0,000 8,791E-03 0,02126839 ! autophagic vacuole GO:0005776 11 10 0,000 8,791E-03 0,02125399 ! NAD metabolic process GO:0019674 10 10 0,000 8,791E-03 0,02123961 ! stereocilium GO:0032420 10 10 0,000 8,791E-03 0,02122525 GO:0032421|stereocilium bundle, ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 8,791E-03 0,02121091 ! regulation of sodium ion transport GO:0002028 10 10 0,000 8,791E-03 0,02119659 ! forebrain cell migration GO:0021885 10 10 0,000 8,791E-03 0,02118228 ! organelle subcompartment GO:0031984 11 10 0,000 8,791E-03 0,021168 ! chondrocyte differentiation GO:0002062 10 10 0,000 8,791E-03 0,02115374 ! negative regulation of ossification GO:0030279 10 10 0,000 8,791E-03 0,02113949 ! regulation of smoothened signaling pathway GO:0008589 10 10 0,000 8,791E-03 0,02112527 ! heparan sulfate proteoglycan metabolic process GO:0030201 10 10 0,000 8,791E-03 0,02111106 ! phosphatidylcholine biosynthetic process GO:0006656 12 10 0,000 8,791E-03 0,02109687 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 10 10 0,000 8,791E-03 0,0210827 ! protein homotetramerization GO:0051289 11 10 0,000 8,791E-03 0,02106855 ! regulation of dephosphorylation GO:0035303 12 10 0,000 8,791E-03 0,02105442 ! oligodendrocyte development GO:0014003 10 10 0,000 8,791E-03 0,02104031 ! positive regulation of phagocytosis GO:0050766 10 10 0,000 8,791E-03 0,02102622 ! response to dsRNA GO:0043331 10 10 0,000 8,791E-03 0,02101215 ! mismatch repair complex binding GO:0032404 11 10 0,000 8,791E-03 0,02099809 ! snRNA metabolic process GO:0016073 10 10 0,000 8,791E-03 0,02098405 GO:0016180|snRNA processing, ! cranial nerve development GO:0021545 10 10 0,000 8,791E-03 0,02097004 ! fucose catabolic process GO:0019317 11 10 0,000 8,791E-03 0,02095604 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 10 10 0,000 8,791E-03 0,02094206 ! retinal binding GO:0016918 10 10 0,000 8,791E-03 0,0209281 ! leukocyte activation during immune response GO:0002366 10 10 0,000 8,791E-03 0,02091415 GO:0002263|cell activation during immune response, ! cerebellum morphogenesis GO:0021587 11 10 0,000 8,791E-03 0,02090023 GO:0021696|cerebellar cortex morphogenesis, ! photoreceptor outer segment GO:0001750 10 10 0,000 8,791E-03 0,02088632 ! negative regulation of MAPKKK cascade GO:0043409 10 10 0,000 8,791E-03 0,02087244 ! regulation of T-helper 2 type immune response GO:0002828 10 10 0,000 8,791E-03 0,02085857 ! ribonuclease P activity GO:0004526 10 10 0,000 8,791E-03 0,02084472 ! midbrain development GO:0030901 10 10 0,000 8,791E-03 0,02083089 ! musculoskeletal movement GO:0050881 10 10 0,000 8,791E-03 0,02081707 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 10 10 0,000 8,791E-03 0,02080328 ! regulation of T-helper cell differentiation GO:0045622 10 10 0,000 8,791E-03 0,0207895 ! fatty-acid ligase activity GO:0015645 10 10 0,000 8,791E-03 0,02077574 GO:0004467|long-chain-fatty-acid-CoA ligase activity, ! regulation of mRNA stability GO:0043488 10 10 0,000 8,791E-03 0,020762 ! quaternary ammonium group transport GO:0015697 10 10 0,000 8,791E-03 0,02074828 ! regulation of RNA splicing GO:0043484 10 10 0,000 8,791E-03 0,02073457 ! embryonic gut development GO:0048566 10 10 0,000 8,791E-03 0,02072089 ! positive regulation of amine transport GO:0051954 10 10 0,000 8,791E-03 0,02070722 ! defense response to Gram-positive bacterium GO:0050830 10 10 0,000 8,791E-03 0,02069357 ! mRNA 3'-end processing GO:0031124 10 10 0,000 8,791E-03 0,02067994 ! lysogeny GO:0030069 10 10 0,000 8,791E-03 0,02066632 GO:0019047|provirus integration, ! lamellipodium assembly GO:0030032 11 10 0,000 8,791E-03 0,02065273 ! establishment of cell polarity GO:0030010 10 10 0,000 8,791E-03 0,02063915 ! regulation of synapse organization GO:0050807 10 10 0,000 8,791E-03 0,02062559 ! cell wall macromolecule metabolic process GO:0044036 11 10 0,000 8,791E-03 0,02061205 ! acyl-CoA binding GO:0000062 10 10 0,000 8,791E-03 0,02059852 ! negative regulation of muscle development GO:0048635 11 10 0,000 8,791E-03 0,02058501 GO:0045843|negative regulation of striated muscle development, ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 8,791E-03 0,02057152 ! GDP binding GO:0019003 10 10 0,000 8,791E-03 0,02055805 ! photoreceptor activity GO:0009881 10 10 0,000 8,791E-03 0,0205446 ! somatic diversification of immune receptors via somatic mutation GO:0002566 10 10 0,000 8,791E-03 0,02053116 GO:0016446|somatic hypermutation of immunoglobulin genes, ! cortical cytoskeleton organization GO:0030865 10 10 0,000 8,791E-03 0,02051774 ! nitric-oxide synthase binding GO:0050998 11 10 0,000 8,791E-03 0,02050434 ! nuclear chromosome, telomeric region GO:0000784 10 10 0,000 8,791E-03 0,02049096 ! nucleotidase activity GO:0008252 10 10 0,000 8,791E-03 0,02047759 ! detection of mechanical stimulus GO:0050982 10 10 0,000 8,791E-03 0,02046424 ! protein complex disassembly GO:0043241 11 10 0,000 8,791E-03 0,02045091 GO:0043624|cellular protein complex disassembly, ! androgen metabolic process GO:0008209 10 10 0,000 8,791E-03 0,02043759 ! lateral plasma membrane GO:0016328 10 10 0,000 8,791E-03 0,0204243 ! estrogen metabolic process GO:0008210 10 10 0,000 8,791E-03 0,02041102 ! nucleocytoplasmic transporter activity GO:0005487 10 10 0,000 8,791E-03 0,02039776 ! retinol dehydrogenase activity GO:0004745 10 10 0,000 8,791E-03 0,02038451 ! negative regulation of cell-matrix adhesion GO:0001953 12 10 0,000 8,791E-03 0,02037128 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 11 10 0,000 8,791E-03 0,02035807 ! interleukin-1 binding GO:0019966 10 10 0,000 8,791E-03 0,02034488 ! endothelial cell differentiation GO:0045446 10 10 0,000 8,791E-03 0,0203317 ! cullin-RING ubiquitin ligase complex GO:0031461 10 10 0,000 8,791E-03 0,02031854 ! acid phosphatase activity GO:0003993 10 10 0,000 8,791E-03 0,0203054 ! regulation of stress fiber formation GO:0051492 13 10 0,000 8,791E-03 0,02029227 ! sodium:potassium-exchanging ATPase activity GO:0005391 11 10 0,000 8,791E-03 0,02027916 ! calcium-transporting ATPase activity GO:0005388 12 10 0,000 8,791E-03 0,02026607 ! telomeric DNA binding GO:0042162 11 10 0,000 8,791E-03 0,020253 ! regulation of intracellular pH GO:0051453 10 10 0,000 8,791E-03 0,02023994 ! lipid digestion GO:0044241 10 10 0,000 8,791E-03 0,0202269 ! multicellular organism growth GO:0035264 10 10 0,000 8,791E-03 0,02021387 ! receptor clustering GO:0043113 10 10 0,000 8,791E-03 0,02020087 ! L-glutamate transmembrane transporter activity GO:0005313 10 10 0,000 8,791E-03 0,02018787 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 11 10 0,000 8,791E-03 0,0201749 ! actin cytoskeleton reorganization GO:0031532 12 10 0,000 8,791E-03 0,02016194 ! signalosome GO:0008180 10 10 0,000 8,791E-03 0,020149 ! prefoldin complex GO:0016272 10 10 0,000 8,791E-03 0,02013608 ! neuromuscular junction GO:0031594 10 10 0,000 8,791E-03 0,02012317 ! regulation of bone resorption GO:0045124 11 10 0,000 8,791E-03 0,02011028 ! positive regulation of peptide secretion GO:0002793 10 10 0,000 8,791E-03 0,0200974 ! alpha-beta T cell differentiation GO:0046632 11 10 0,000 8,791E-03 0,02008455 ! negative regulation of myeloid leukocyte differentiation GO:0002762 10 10 0,000 8,791E-03 0,0200717 ! positive regulation of T cell mediated immunity GO:0002711 14 10 0,000 8,791E-03 0,02005888 ! taste receptor activity GO:0008527 10 10 0,000 8,791E-03 0,02004607 ! Ran GTPase binding GO:0008536 10 10 0,000 8,791E-03 0,02003328 ! endocytic vesicle membrane GO:0030666 10 10 0,000 8,791E-03 0,0200205 ! regulation of interleukin-12 production GO:0032655 10 10 0,000 8,791E-03 0,02000774 ! ribosome assembly GO:0042255 10 10 0,000 8,791E-03 0,019995 ! DNA methylation GO:0006306 12 10 0,000 8,791E-03 0,01998227 GO:0006305|DNA alkylation, ! protein-hormone receptor activity GO:0016500 10 10 0,000 8,791E-03 0,01996956 ! bile acid transmembrane transporter activity GO:0015125 10 10 0,000 8,791E-03 0,01995686 ! proteasome accessory complex GO:0022624 11 10 0,000 8,791E-03 0,01994418 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 13 10 0,000 8,791E-03 0,01993152 ! prostaglandin receptor activity GO:0004955 11 10 0,000 8,791E-03 0,01991887 ! regulation of isotype switching GO:0045191 14 10 0,000 8,791E-03 0,01990624 ! peptide transporter activity GO:0015197 10 10 0,000 8,791E-03 0,01989363 ! regulation of leukocyte migration GO:0002685 10 10 0,000 8,791E-03 0,01988103 ! retinoid-X receptor activity GO:0004886 10 10 0,000 8,791E-03 0,01986845 ! GTPase inhibitor activity GO:0005095 10 10 0,000 8,791E-03 0,01985588 ! pattern recognition receptor activity GO:0008329 10 10 0,000 8,791E-03 0,01984333 ! germ cell migration GO:0008354 10 10 0,000 8,791E-03 0,01983079 ! regulation of organic acid transport GO:0032890 10 10 0,000 8,791E-03 0,01981827 ! negative regulation of mast cell proliferation GO:0070667 10 10 0,000 8,791E-03 0,01980577 GO:0042130|negative regulation of T cell proliferation, ! cardiac cell differentiation GO:0035051 11 10 0,000 8,791E-03 0,01979328 ! amiloride-sensitive sodium channel activity GO:0015280 10 10 0,000 8,791E-03 0,01978081 ! sterol transporter activity GO:0015248 10 10 0,000 8,791E-03 0,01976835 ! regulation of embryonic development GO:0045995 11 10 0,000 8,791E-03 0,01975591 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 11 11 0,000 9,666E-03 0,021709 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 11 0,000 9,666E-03 0,02169535 ! negative regulation of blood pressure GO:0045776 11 11 0,000 9,666E-03 0,02168173 ! RNA cap binding GO:0000339 12 11 0,000 9,666E-03 0,02166812 ! CTP metabolic process GO:0046036 12 11 0,000 9,666E-03 0,02165452 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 11 0,000 9,666E-03 0,02164095 ! response to pain GO:0048265 11 11 0,000 9,666E-03 0,02162739 ! axonemal dynein complex GO:0005858 11 11 0,000 9,666E-03 0,02161384 ! eukaryotic translation initiation factor 3 complex GO:0005852 11 11 0,000 9,666E-03 0,02160032 ! dopamine receptor signaling pathway GO:0007212 13 11 0,000 9,666E-03 0,02158681 ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 11 0,000 9,666E-03 0,02157332 ! endocrine pancreas development GO:0031018 11 11 0,000 9,666E-03 0,02155984 ! regulation of interferon-gamma biosynthetic process GO:0045072 12 11 0,000 9,666E-03 0,02154638 ! regulation of exit from mitosis GO:0007096 11 11 0,000 9,666E-03 0,02153294 ! chylomicron GO:0042627 11 11 0,000 9,666E-03 0,02151952 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 11 11 0,000 9,666E-03 0,02150611 ! glycolipid biosynthetic process GO:0009247 11 11 0,000 9,666E-03 0,02149272 ! transforming growth factor beta binding GO:0050431 11 11 0,000 9,666E-03 0,02147935 ! glutamate metabolic process GO:0006536 12 11 0,000 9,666E-03 0,02146599 ! ribonucleotide catabolic process GO:0009261 11 11 0,000 9,666E-03 0,02145265 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 9,666E-03 0,02143932 ! vascular endothelial growth factor receptor activity GO:0005021 11 11 0,000 9,666E-03 0,02142601 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 11 11 0,000 9,666E-03 0,02141272 GO:0045125|bioactive lipid receptor activity, ! Rac GTPase binding GO:0048365 11 11 0,000 9,666E-03 0,02139945 ! epithelial cell development GO:0002064 11 11 0,000 9,666E-03 0,02138619 ! filamentous actin GO:0031941 11 11 0,000 9,666E-03 0,02137295 ! temperature homeostasis GO:0001659 11 11 0,000 9,666E-03 0,02135972 ! structural constituent of epidermis GO:0030280 13 11 0,000 9,666E-03 0,02134651 ! protein targeting to peroxisome GO:0006625 11 11 0,000 9,666E-03 0,02133332 ! spectrin GO:0008091 11 11 0,000 9,666E-03 0,02132014 ! cytoskeletal adaptor activity GO:0008093 14 11 0,000 9,666E-03 0,02130698 ! negative regulation of axonogenesis GO:0050771 13 11 0,000 9,666E-03 0,02129384 ! regulation of phagocytosis GO:0050764 11 11 0,000 9,666E-03 0,02128071 ! nucleoside triphosphate catabolic process GO:0009143 11 11 0,000 9,666E-03 0,0212676 ! synaptic vesicle exocytosis GO:0016079 12 11 0,000 9,666E-03 0,0212545 ! regulation of B cell differentiation GO:0045577 15 11 0,000 9,666E-03 0,02124142 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 11 11 0,000 9,666E-03 0,02122836 ! basal lamina GO:0005605 12 11 0,000 9,666E-03 0,02121531 ! gastrulation with mouth forming second GO:0001702 12 11 0,000 9,666E-03 0,02120228 ! spinal cord motor neuron differentiation GO:0021522 11 11 0,000 9,666E-03 0,02118926 ! hindbrain morphogenesis GO:0021575 13 11 0,000 9,666E-03 0,02117626 ! regulation of hormone metabolic process GO:0032350 12 11 0,000 9,666E-03 0,02116328 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 11 0,000 9,666E-03 0,02115031 GO:0050706|regulation of interleukin-1 beta secretion, ! COPI vesicle coat GO:0030126 11 11 0,000 9,666E-03 0,02113736 GO:0030663|COPI coated vesicle membrane, ! clathrin coat of trans-Golgi network vesicle GO:0030130 14 11 0,000 9,666E-03 0,02112442 ! tRNA-specific ribonuclease activity GO:0004549 11 11 0,000 9,666E-03 0,0211115 ! cofactor transporter activity GO:0051184 11 11 0,000 9,666E-03 0,0210986 ! cobalt ion binding GO:0050897 11 11 0,000 9,666E-03 0,02108571 ! aromatic amino acid family catabolic process GO:0009074 12 11 0,000 9,666E-03 0,02107284 ! serine family amino acid biosynthetic process GO:0009070 11 11 0,000 9,666E-03 0,02105998 ! thymus development GO:0048538 12 11 0,000 9,666E-03 0,02104714 ! spleen development GO:0048536 12 11 0,000 9,666E-03 0,02103431 ! regulation of RNA stability GO:0043487 11 11 0,000 9,666E-03 0,0210215 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 12 11 0,000 9,666E-03 0,02100871 ! acid-thiol ligase activity GO:0016878 11 11 0,000 9,666E-03 0,02099593 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 11 11 0,000 9,666E-03 0,02098317 ! blastocyst formation GO:0001825 11 11 0,000 9,666E-03 0,02097042 ! cerebellar cortex development GO:0021695 12 11 0,000 9,666E-03 0,02095769 ! regulation of actin filament bundle formation GO:0032231 14 11 0,000 9,666E-03 0,02094497 ! ADP binding GO:0043531 11 11 0,000 9,666E-03 0,02093227 ! folic acid binding GO:0005542 11 11 0,000 9,666E-03 0,02091958 ! FK506 binding GO:0005528 11 11 0,000 9,666E-03 0,02090691 GO:0005527|macrolide binding, ! defense response to fungus GO:0050832 11 11 0,000 9,666E-03 0,02089425 ! extracellular matrix binding GO:0050840 13 11 0,000 9,666E-03 0,02088161 ! microspike assembly GO:0030035 13 11 0,000 9,666E-03 0,02086899 ! cytoplasmic sequestering of protein GO:0051220 11 11 0,000 9,666E-03 0,02085638 ! regulation of synapse structure and activity GO:0050803 11 11 0,000 9,666E-03 0,02084379 ! organ formation GO:0048645 12 11 0,000 9,666E-03 0,02083121 ! embryonic hindlimb morphogenesis GO:0035116 11 11 0,000 9,666E-03 0,02081864 ! embryonic forelimb morphogenesis GO:0035115 11 11 0,000 9,666E-03 0,02080609 ! cellular copper ion homeostasis GO:0006878 12 11 0,000 9,666E-03 0,02079356 ! glycosaminoglycan catabolic process GO:0006027 11 11 0,000 9,666E-03 0,02078104 ! Golgi vesicle budding GO:0048194 11 11 0,000 9,666E-03 0,02076854 ! regulation of positive chemotaxis GO:0050926 11 11 0,000 9,666E-03 0,02075605 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 11 11 0,000 9,666E-03 0,02074357 ! ion channel inhibitor activity GO:0008200 13 11 0,000 9,666E-03 0,02073112 GO:0016248|channel inhibitor activity, ! positive regulation of transcription factor import into nucleus GO:0042993 12 11 0,000 9,666E-03 0,02071867 ! MAP kinase kinase activity GO:0004708 11 11 0,000 9,666E-03 0,02070624 GO:0004712|protein serine/threonine/tyrosine kinase activity, ! cation:amino acid symporter activity GO:0005416 11 11 0,000 9,666E-03 0,02069383 ! mannosyltransferase activity GO:0000030 11 11 0,000 9,666E-03 0,02068143 ! cAMP-dependent protein kinase activity GO:0004691 11 11 0,000 9,666E-03 0,02066905 ! FMN binding GO:0010181 11 11 0,000 9,666E-03 0,02065668 ! response to X-ray GO:0010165 12 11 0,000 9,666E-03 0,02064432 ! focal adhesion formation GO:0048041 13 11 0,000 9,666E-03 0,02063198 ! actin polymerization or depolymerization GO:0008154 13 11 0,000 9,666E-03 0,02061966 ! substrate-bound cell migration GO:0006929 11 11 0,000 9,666E-03 0,02060735 ! integrator complex GO:0032039 11 11 0,000 9,666E-03 0,02059505 ! UV protection GO:0009650 11 11 0,000 9,666E-03 0,02058277 ! L-glutamate transport GO:0015813 11 11 0,000 9,666E-03 0,02057051 GO:0015800|acidic amino acid transport, ! retinol binding GO:0019841 11 11 0,000 9,666E-03 0,02055825 ! regulation of organ growth GO:0046620 12 11 0,000 9,666E-03 0,02054602 ! regulation of cytokine production during immune response GO:0002718 11 11 0,000 9,666E-03 0,02053379 ! regulation of T cell mediated immunity GO:0002709 15 11 0,000 9,666E-03 0,02052159 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 11 11 0,000 9,666E-03 0,02050939 ! regulation of interleukin-8 production GO:0032677 12 11 0,000 9,666E-03 0,02049721 ! histone acetylation GO:0016573 11 11 0,000 9,666E-03 0,02048505 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 12 11 0,000 9,666E-03 0,0204729 ! delayed rectifier potassium channel activity GO:0005251 11 11 0,000 9,666E-03 0,02046076 ! organic cation transmembrane transporter activity GO:0015101 11 11 0,000 9,666E-03 0,02044864 ! chromatin silencing GO:0006342 11 11 0,000 9,666E-03 0,02043654 ! gland morphogenesis GO:0022612 12 11 0,000 9,666E-03 0,02042444 ! sulfate transmembrane transporter activity GO:0015116 11 11 0,000 9,666E-03 0,02041236 ! hexose transmembrane transporter activity GO:0015149 11 11 0,000 9,666E-03 0,0204003 ! icosanoid receptor activity GO:0004953 12 11 0,000 9,666E-03 0,02038825 GO:0004954|prostanoid receptor activity, ! non-G-protein coupled 7TM receptor activity GO:0004926 12 11 0,000 9,666E-03 0,02037622 ! negative regulation of neurological system process GO:0031645 12 11 0,000 9,666E-03 0,02036419 ! acid secretion GO:0046717 11 11 0,000 9,666E-03 0,02035219 ! nitric oxide mediated signal transduction GO:0007263 11 11 0,000 9,666E-03 0,02034019 ! thyroid hormone metabolic process GO:0042403 11 11 0,000 9,666E-03 0,02032821 ! quinone cofactor metabolic process GO:0042375 12 11 0,000 9,666E-03 0,02031625 ! insulin-like growth factor receptor binding GO:0005159 12 11 0,000 9,666E-03 0,0203043 ! midbody GO:0030496 11 11 0,000 9,666E-03 0,02029236 ! interferon-alpha/beta receptor binding GO:0005132 11 11 0,000 9,666E-03 0,02028044 ! cAMP-dependent protein kinase complex GO:0005952 11 11 0,000 9,666E-03 0,02026853 ! water channel activity GO:0015250 11 11 0,000 9,666E-03 0,02025664 ! response to nicotine GO:0035094 11 11 0,000 9,666E-03 0,02024476 ! response to cold GO:0009409 11 11 0,000 9,666E-03 0,02023289 ! adenylate cyclase activity GO:0004016 11 11 0,000 9,666E-03 0,02022104 ! 'de novo' protein folding GO:0006458 12 12 0,000 0,01054044 0,02203743 ! organellar large ribosomal subunit GO:0000315 13 12 0,000 0,01054044 0,02202453 GO:0005762|mitochondrial large ribosomal subunit, ! cadmium ion binding GO:0046870 13 12 0,000 0,01054044 0,02201165 ! folic acid and derivative biosynthetic process GO:0009396 12 12 0,000 0,01054044 0,02199879 ! bone remodeling GO:0046849 12 12 0,000 0,01054044 0,02198594 ! peroxisomal transport GO:0043574 12 12 0,000 0,01054044 0,0219731 ! retina development in camera-type eye GO:0060041 13 12 0,000 0,01054044 0,02196028 ! hair follicle morphogenesis GO:0031069 12 12 0,000 0,01054044 0,02194748 ! voltage-gated sodium channel complex GO:0001518 13 12 0,000 0,01054044 0,02193469 GO:0034706|sodium channel complex, ! regulation of excitatory postsynaptic membrane potential GO:0060079 14 12 0,000 0,01054044 0,02192191 ! hippocampus development GO:0021766 12 12 0,000 0,01054044 0,02190915 ! T cell selection GO:0045058 16 12 0,000 0,01054044 0,02189641 ! cation:cation antiporter activity GO:0015491 12 12 0,000 0,01054044 0,02188368 ! induction of apoptosis via death domain receptors GO:0008625 12 12 0,000 0,01054044 0,02187096 ! T-tubule GO:0030315 13 12 0,000 0,01054044 0,02185826 ! methionine metabolic process GO:0006555 13 12 0,000 0,01054044 0,02184557 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 14 12 0,000 0,01054044 0,0218329 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! peptide antigen binding GO:0042605 12 12 0,000 0,01054044 0,02182025 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01054044 0,0218076 ! cell-cell junction assembly GO:0007043 12 12 0,000 0,01054044 0,02179498 ! mitotic spindle organization GO:0007052 12 12 0,000 0,01054044 0,02178236 ! fear response GO:0042596 12 12 0,000 0,01054044 0,02176977 ! negative regulation of mitotic cell cycle GO:0045930 13 12 0,000 0,01054044 0,02175718 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01054044 0,02174461 ! copper ion homeostasis GO:0055070 13 12 0,000 0,01054044 0,02173206 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01054044 0,02171952 ! axon cargo transport GO:0008088 12 12 0,000 0,01054044 0,02170699 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 13 12 0,000 0,01054044 0,02169448 ! transcription elongation factor complex GO:0008023 13 12 0,000 0,01054044 0,02168198 ! positive regulation of Ras GTPase activity GO:0032320 12 12 0,000 0,01054044 0,0216695 ! nuclear outer membrane GO:0005640 12 12 0,000 0,01054044 0,02165703 ! beta-tubulin binding GO:0048487 12 12 0,000 0,01054044 0,02164458 ! autonomic nervous system development GO:0048483 12 12 0,000 0,01054044 0,02163214 ! positive regulation of interleukin-1 secretion GO:0050716 12 12 0,000 0,01054044 0,02161972 GO:0050704|regulation of interleukin-1 secretion, ! exoribonuclease activity GO:0004532 12 12 0,000 0,01054044 0,0216073 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! cofactor transport GO:0051181 12 12 0,000 0,01054044 0,02159491 ! regulation of epidermis development GO:0045682 12 12 0,000 0,01054044 0,02158253 ! protein-chromophore linkage GO:0018298 12 12 0,000 0,01054044 0,02157016 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 12 12 0,000 0,01054044 0,0215578 ! cell killing GO:0001906 12 12 0,000 0,01054044 0,02154546 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 12 0,000 0,01054044 0,02153314 ! lymphocyte homeostasis GO:0002260 14 12 0,000 0,01054044 0,02152083 ! regulation of fatty acid oxidation GO:0046320 13 12 0,000 0,01054044 0,02150853 ! detection of bacterium GO:0016045 13 12 0,000 0,01054044 0,02149624 ! positive regulation of neuron apoptosis GO:0043525 12 12 0,000 0,01054044 0,02148398 ! dystrophin-associated glycoprotein complex GO:0016010 14 12 0,000 0,01054044 0,02147172 ! internal side of plasma membrane GO:0009898 14 12 0,000 0,01054044 0,02145948 ! RNA 3'-end processing GO:0031123 12 12 0,000 0,01054044 0,02144725 ! developmental induction GO:0031128 13 12 0,000 0,01054044 0,02143504 GO:0045168|cell-cell signaling involved in cell fate specification, ! fibrillar collagen GO:0005583 13 12 0,000 0,01054044 0,02142284 ! positive regulation of calcium-mediated signaling GO:0050850 14 12 0,000 0,01054044 0,02141065 ! inner ear receptor cell differentiation GO:0060113 13 12 0,000 0,01054044 0,02139848 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01054044 0,02138632 ! very-long-chain fatty acid metabolic process GO:0000038 12 12 0,000 0,01054044 0,02137418 ! negative regulation of cell projection organization GO:0031345 14 12 0,000 0,01054044 0,02136205 ! thyroid gland development GO:0030878 12 12 0,000 0,01054044 0,02134993 ! non-recombinational repair GO:0000726 12 12 0,000 0,01054044 0,02133783 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 12 12 0,000 0,01054044 0,02132574 ! lipid localization GO:0010876 12 12 0,000 0,01054044 0,02131366 GO:0019915|lipid storage, ! regulation of glycolysis GO:0006110 12 12 0,000 0,01054044 0,0213016 ! response to cAMP GO:0051591 12 12 0,000 0,01054044 0,02128955 ! negative regulation of transcription factor import into nucleus GO:0042992 12 12 0,000 0,01054044 0,02127752 ! T cell proliferation GO:0042098 17 12 0,000 0,01054044 0,02126549 ! negative regulation of protein amino acid phosphorylation GO:0001933 16 12 0,000 0,01054044 0,02125349 ! receptor signaling protein tyrosine kinase activity GO:0004716 13 12 0,000 0,01054044 0,02124149 ! two-component signal transduction system (phosphorelay) GO:0000160 13 12 0,000 0,01054044 0,02122951 ! peptide or protein amino-terminal blocking GO:0018409 13 12 0,000 0,01054044 0,02121754 ! drug transport GO:0015893 12 12 0,000 0,01054044 0,02120559 ! GTP-dependent protein binding GO:0030742 12 12 0,000 0,01054044 0,02119365 ! regulation of interleukin-6 biosynthetic process GO:0045408 12 12 0,000 0,01054044 0,02118172 ! T cell receptor complex GO:0042101 12 12 0,000 0,01054044 0,02116981 ! membrane protein proteolysis GO:0033619 13 12 0,000 0,01054044 0,02115791 GO:0006509|membrane protein ectodomain proteolysis, ! negative regulation of caspase activity GO:0043154 12 12 0,000 0,01054044 0,02114602 ! protein disulfide oxidoreductase activity GO:0015035 12 12 0,000 0,01054044 0,02113415 ! histone acetyltransferase complex GO:0000123 13 12 0,000 0,01054044 0,02112229 ! dendritic spine GO:0043197 12 12 0,000 0,01054044 0,02111045 ! ATP-binding cassette (ABC) transporter complex GO:0043190 12 12 0,000 0,01054044 0,02109861 ! alpha-beta T cell activation GO:0046631 13 12 0,000 0,01054044 0,02108679 ! organic anion transmembrane transporter activity GO:0008514 13 12 0,000 0,01054044 0,02107499 ! vasoconstriction GO:0042310 13 12 0,000 0,01054044 0,02106319 ! DNA unwinding during replication GO:0006268 12 12 0,000 0,01054044 0,02105141 ! cellular amino acid derivative catabolic process GO:0042219 16 12 0,000 0,01054044 0,02103964 ! mRNA splice site selection GO:0006376 13 12 0,000 0,01054044 0,02102789 ! phosphate transmembrane transporter activity GO:0015114 13 12 0,000 0,01054044 0,02101615 ! trans-Golgi network transport vesicle membrane GO:0012510 15 12 0,000 0,01054044 0,02100442 ! ubiquitin protein ligase binding GO:0031625 12 12 0,000 0,01054044 0,02099271 ! monosaccharide transmembrane transporter activity GO:0015145 12 12 0,000 0,01054044 0,02098101 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 12 12 0,000 0,01054044 0,02096932 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01054044 0,02095764 ! diacylglycerol kinase activity GO:0004143 13 12 0,000 0,01054044 0,02094598 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01054044 0,02093433 ! activation of NF-kappaB-inducing kinase activity GO:0007250 12 12 0,000 0,01054044 0,02092269 ! catecholamine biosynthetic process GO:0042423 13 12 0,000 0,01054044 0,02091107 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 15 12 0,000 0,01054044 0,02089946 ! establishment or maintenance of apical/basal cell polarity GO:0035088 12 12 0,000 0,01054044 0,02088786 ! L-fucose metabolic process GO:0042354 14 12 0,000 0,01054044 0,02087628 ! acylglycerol O-acyltransferase activity GO:0016411 12 12 0,000 0,01054044 0,0208647 ! C-acyltransferase activity GO:0016408 12 12 0,000 0,01054044 0,02085314 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01054044 0,0208416 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01054044 0,02083006 ! calcium-activated potassium channel activity GO:0015269 14 12 0,000 0,01054044 0,02081854 ! SWI/SNF-type complex GO:0070603 13 12 0,000 0,01054044 0,02080703 GO:0016514|SWI/SNF complex, ! cilium part GO:0044441 12 12 0,000 0,01054044 0,02079554 ! positive regulation of translation GO:0045727 13 13 0,000 0,01141417 0,0225069 ! ER-associated protein catabolic process GO:0030433 13 13 0,000 0,01141417 0,02249448 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01141417 0,02248207 ! superoxide anion generation GO:0042554 13 13 0,000 0,01141417 0,02246968 ! pteridine and derivative biosynthetic process GO:0042559 14 13 0,000 0,01141417 0,0224573 ! cis-Golgi network GO:0005801 14 13 0,000 0,01141417 0,02244493 ! regulation of S phase GO:0033261 17 13 0,000 0,01141417 0,02243258 ! regulation of chemokine production GO:0032642 13 13 0,000 0,01141417 0,02242024 ! phospholipid catabolic process GO:0009395 14 13 0,000 0,01141417 0,02240791 ! positive regulation of GTPase activity GO:0043547 14 13 0,000 0,01141417 0,0223956 ! endothelial cell migration GO:0043542 13 13 0,000 0,01141417 0,0223833 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 13 13 0,000 0,01141417 0,02237102 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01141417 0,02235875 ! cartilage condensation GO:0001502 14 13 0,000 0,01141417 0,02234649 ! organelle fusion GO:0048284 14 13 0,000 0,01141417 0,02233424 ! positive regulation of lipid metabolic process GO:0045834 13 13 0,000 0,01141417 0,02232201 ! negative regulation of gene expression, epigenetic GO:0045814 13 13 0,000 0,01141417 0,02230979 ! positive regulation of cell growth GO:0030307 13 13 0,000 0,01141417 0,02229759 ! regulation of interleukin-2 biosynthetic process GO:0045076 13 13 0,000 0,01141417 0,0222854 ! negative regulation of proteolysis GO:0045861 13 13 0,000 0,01141417 0,02227322 ! regulation of mRNA processing GO:0050684 13 13 0,000 0,01141417 0,02226106 ! arginine metabolic process GO:0006525 13 13 0,000 0,01141417 0,02224891 ! WW domain binding GO:0050699 14 13 0,000 0,01141417 0,02223677 ! cholesterol binding GO:0015485 13 13 0,000 0,01141417 0,02222464 ! negative regulation of microtubule depolymerization GO:0007026 15 13 0,000 0,01141417 0,02221253 GO:0031114|regulation of microtubule depolymerization, ! Golgi organization GO:0007030 16 13 0,000 0,01141417 0,02220043 ! negative regulation of endothelial cell migration GO:0010596 13 13 0,000 0,01141417 0,02218835 ! integral to peroxisomal membrane GO:0005779 13 13 0,000 0,01141417 0,02217628 GO:0031231|intrinsic to peroxisomal membrane, ! integral to membrane of membrane fraction GO:0000299 14 13 0,000 0,01141417 0,02216422 ! regulation of heart rate GO:0002027 14 13 0,000 0,01141417 0,02215217 ! positive regulation of carbohydrate metabolic process GO:0045913 14 13 0,000 0,01141417 0,02214014 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 14 13 0,000 0,01141417 0,02212812 ! negative regulation of immune response GO:0050777 17 13 0,000 0,01141417 0,02211611 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 13 0,000 0,01141417 0,02210412 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01141417 0,02209214 ! response to estradiol stimulus GO:0032355 14 13 0,000 0,01141417 0,02208017 ! anaphase-promoting complex GO:0005680 13 13 0,000 0,01141417 0,02206822 ! nucleotide diphosphatase activity GO:0004551 13 13 0,000 0,01141417 0,02205627 ! NADP metabolic process GO:0006739 13 13 0,000 0,01141417 0,02204435 ! regulation of erythrocyte differentiation GO:0045646 13 13 0,000 0,01141417 0,02203243 ! intestinal absorption GO:0050892 13 13 0,000 0,01141417 0,02202053 ! eukaryotic cell surface binding GO:0043499 14 13 0,000 0,01141417 0,02200864 ! digestive tract morphogenesis GO:0048546 13 13 0,000 0,01141417 0,02199676 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 14 13 0,000 0,01141417 0,02198489 ! regulation of cellular carbohydrate catabolic process GO:0043471 14 13 0,000 0,01141417 0,02197304 GO:0043470|regulation of carbohydrate catabolic process, ! tropomyosin binding GO:0005523 13 13 0,000 0,01141417 0,0219612 ! carbon-sulfur lyase activity GO:0016846 13 13 0,000 0,01141417 0,02194938 ! embryonic placenta development GO:0001892 13 13 0,000 0,01141417 0,02193756 ! positive regulation of protein polymerization GO:0032273 13 13 0,000 0,01141417 0,02192576 ! insulin secretion GO:0030073 13 13 0,000 0,01141417 0,02191398 ! positive regulation of cellular catabolic process GO:0031331 14 13 0,000 0,01141417 0,0219022 ! G1 phase of mitotic cell cycle GO:0000080 13 13 0,000 0,01141417 0,02189044 ! replisome GO:0030894 14 13 0,000 0,01141417 0,02187869 GO:0043601|nuclear replisome, ! regulation of nitric-oxide synthase activity GO:0050999 13 13 0,000 0,01141417 0,02186695 ! copper ion transport GO:0006825 13 13 0,000 0,01141417 0,02185523 ! regulation of cell-cell adhesion GO:0022407 13 13 0,000 0,01141417 0,02184351 ! forelimb morphogenesis GO:0035136 13 13 0,000 0,01141417 0,02183181 ! mating GO:0007618 13 13 0,000 0,01141417 0,02182013 ! phosphatidylinositol phosphate kinase activity GO:0016307 14 13 0,000 0,01141417 0,02180845 ! MAP kinase activity GO:0004707 14 13 0,000 0,01141417 0,02179679 ! cytokine biosynthetic process GO:0042089 13 13 0,000 0,01141417 0,02178514 ! ventral spinal cord development GO:0021517 13 13 0,000 0,01141417 0,0217735 ! prenyltransferase activity GO:0004659 14 13 0,000 0,01141417 0,02176188 ! platelet-derived growth factor receptor signaling pathway GO:0048008 15 13 0,000 0,01141417 0,02175026 ! regulation of skeletal muscle fiber development GO:0048742 13 13 0,000 0,01141417 0,02173866 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 15 13 0,000 0,01141417 0,02172708 ! protein kinase C activity GO:0004697 15 13 0,000 0,01141417 0,0217155 ! oligodendrocyte differentiation GO:0048709 13 13 0,000 0,01141417 0,02170394 ! water transporter activity GO:0005372 13 13 0,000 0,01141417 0,02169239 ! exocrine system development GO:0035272 14 13 0,000 0,01141417 0,02168085 ! dicarboxylic acid transmembrane transporter activity GO:0005310 13 13 0,000 0,01141417 0,02166932 ! monoamine transport GO:0015844 13 13 0,000 0,01141417 0,02165781 ! CoA hydrolase activity GO:0016289 13 13 0,000 0,01141417 0,02164631 ! embryo implantation GO:0007566 13 13 0,000 0,01141417 0,02163482 ! G1/S transition checkpoint GO:0031575 13 13 0,000 0,01141417 0,02162334 ! positive regulation of alpha-beta T cell differentiation GO:0046638 13 13 0,000 0,01141417 0,02161187 ! immunoglobulin binding GO:0019865 13 13 0,000 0,01141417 0,02160042 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01141417 0,02158898 ! anchored to plasma membrane GO:0046658 14 13 0,000 0,01141417 0,02157755 ! MHC class I protein binding GO:0042288 13 13 0,000 0,01141417 0,02156613 ! histone deacetylation GO:0016575 13 13 0,000 0,01141417 0,02155473 ! calcium channel regulator activity GO:0005246 14 13 0,000 0,01141417 0,02154334 ! neuroblast proliferation GO:0007405 13 13 0,000 0,01141417 0,02153196 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01141417 0,02152059 ! response to gamma radiation GO:0010332 13 13 0,000 0,01141417 0,02150923 ! sarcomere organization GO:0045214 13 13 0,000 0,01141417 0,02149789 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 15 13 0,000 0,01141417 0,02148656 ! cAMP binding GO:0030552 13 13 0,000 0,01141417 0,02147523 ! fucosyltransferase activity GO:0008417 14 13 0,000 0,01141417 0,02146393 ! cilium assembly GO:0042384 13 13 0,000 0,01141417 0,02145263 ! negative regulation of leukocyte proliferation GO:0070664 13 13 0,000 0,01141417 0,02144134 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! bacterial binding GO:0008367 13 13 0,000 0,01141417 0,02143007 ! regulation of NF-kappaB import into nucleus GO:0042345 13 13 0,000 0,01141417 0,02141881 ! acrosome reaction GO:0007340 13 13 0,000 0,01141417 0,02140756 ! microtubule-based flagellum GO:0009434 13 13 0,000 0,01141417 0,02139632 ! axoneme part GO:0044447 13 13 0,000 0,01141417 0,0213851 ! tRNA modification GO:0006400 14 14 0,000 0,01228718 0,02300866 ! positive regulation of blood pressure GO:0045777 15 14 0,000 0,01228718 0,02299661 ! transferase activity, transferring amino-acyl groups GO:0016755 14 14 0,000 0,01228718 0,02298456 ! negative regulation of bone remodeling GO:0046851 14 14 0,000 0,01228718 0,02297252 ! 2'-deoxyribonucleotide metabolic process GO:0009394 15 14 0,000 0,01228718 0,0229605 GO:0019692|deoxyribose phosphate metabolic process, ! transcription from RNA polymerase III promoter GO:0006383 14 14 0,000 0,01228718 0,0229485 ! guanylate kinase activity GO:0004385 16 14 0,000 0,01228718 0,0229365 ! striated muscle thin filament GO:0005865 15 14 0,000 0,01228718 0,02292452 ! patterning of blood vessels GO:0001569 14 14 0,000 0,01228718 0,02291254 ! mechanoreceptor differentiation GO:0042490 15 14 0,000 0,01228718 0,02290059 ! palate development GO:0060021 15 14 0,000 0,01228718 0,02288864 ! regulation of defense response to virus GO:0050688 14 14 0,000 0,01228718 0,02287671 ! cAMP-dependent protein kinase regulator activity GO:0008603 14 14 0,000 0,01228718 0,02286479 ! ephrin receptor activity GO:0005003 16 14 0,000 0,01228718 0,02285288 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01228718 0,02284098 ! glycine metabolic process GO:0006544 15 14 0,000 0,01228718 0,0228291 ! plasma membrane organization GO:0007009 14 14 0,000 0,01228718 0,02281722 ! tyrosine metabolic process GO:0006570 16 14 0,000 0,01228718 0,02280537 ! response to retinoic acid GO:0032526 14 14 0,000 0,01228718 0,02279352 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 16 14 0,000 0,01228718 0,02278168 ! lysosomal transport GO:0007041 14 14 0,000 0,01228718 0,02276986 ! rough endoplasmic reticulum GO:0005791 14 14 0,000 0,01228718 0,02275805 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 14 14 0,000 0,01228718 0,02274625 ! regulation of the force of heart contraction GO:0002026 15 14 0,000 0,01228718 0,02273447 ! bone mineralization GO:0030282 14 14 0,000 0,01228718 0,02272269 ! protein kinase activator activity GO:0030295 14 14 0,000 0,01228718 0,02271093 ! NLS-bearing substrate import into nucleus GO:0006607 15 14 0,000 0,01228718 0,02269918 ! cerebellum development GO:0021549 15 14 0,000 0,01228718 0,02268745 ! G1 phase GO:0051318 14 14 0,000 0,01228718 0,02267572 ! negative regulation of blood coagulation GO:0030195 16 14 0,000 0,01228718 0,02266401 ! negative regulation of protein secretion GO:0050709 14 14 0,000 0,01228718 0,02265231 ! water homeostasis GO:0030104 14 14 0,000 0,01228718 0,02264062 ! peptide hormone binding GO:0017046 14 14 0,000 0,01228718 0,02262894 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01228718 0,02261728 ! glutamine family amino acid biosynthetic process GO:0009084 15 14 0,000 0,01228718 0,02260563 ! regulation of ATPase activity GO:0043462 15 14 0,000 0,01228718 0,02259399 ! racemase and epimerase activity GO:0016854 14 14 0,000 0,01228718 0,02258236 ! regulation of leukocyte mediated cytotoxicity GO:0001910 18 14 0,000 0,01228718 0,02257074 ! release of cytochrome c from mitochondria GO:0001836 14 14 0,000 0,01228718 0,02255914 ! positive regulation of calcium ion transport GO:0051928 17 14 0,000 0,01228718 0,02254754 ! regulation of blood vessel endothelial cell migration GO:0043535 14 14 0,000 0,01228718 0,02253596 ! regulation of calcium-mediated signaling GO:0050848 16 14 0,000 0,01228718 0,0225244 ! positive regulation of synaptic transmission GO:0050806 14 14 0,000 0,01228718 0,02251284 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 16 14 0,000 0,01228718 0,02250129 ! lactation GO:0007595 15 14 0,000 0,01228718 0,02248976 ! reproductive cellular process GO:0048610 14 14 0,000 0,01228718 0,02247824 ! positive regulation of cell killing GO:0031343 18 14 0,000 0,01228718 0,02246673 ! sulfur amino acid biosynthetic process GO:0000097 15 14 0,000 0,01228718 0,02245523 ! dicarboxylic acid transport GO:0006835 14 14 0,000 0,01228718 0,02244375 ! inorganic anion exchanger activity GO:0005452 15 14 0,000 0,01228718 0,02243227 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 15 14 0,000 0,01228718 0,02242081 ! negative regulation of cytokine biosynthetic process GO:0042036 14 14 0,000 0,01228718 0,02240936 ! negative regulation of ion transport GO:0043271 14 14 0,000 0,01228718 0,02239792 ! retinoic acid receptor binding GO:0042974 14 14 0,000 0,01228718 0,02238649 ! startle response GO:0001964 14 14 0,000 0,01228718 0,02237508 ! 2 iron, 2 sulfur cluster binding GO:0051537 14 14 0,000 0,01228718 0,02236367 ! activation of MAPKK activity GO:0000186 15 14 0,000 0,01228718 0,02235228 ! response to hexose stimulus GO:0009746 14 14 0,000 0,01228718 0,0223409 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! cytokine metabolic process GO:0042107 14 14 0,000 0,01228718 0,02232953 ! organic alcohol transport GO:0015850 15 14 0,000 0,01228718 0,02231817 ! preassembly of GPI anchor in ER membrane GO:0016254 15 14 0,000 0,01228718 0,02230682 ! calcium ion transmembrane transporter activity GO:0015085 16 14 0,000 0,01228718 0,02229549 ! eukaryotic translation initiation factor 4F complex GO:0016281 14 14 0,000 0,01228718 0,02228417 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01228718 0,02227285 ! L-amino acid transport GO:0015807 14 14 0,000 0,01228718 0,02226155 ! microfilament motor activity GO:0000146 14 14 0,000 0,01228718 0,02225026 ! stem cell development GO:0048864 14 14 0,000 0,01228718 0,02223899 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 15 14 0,000 0,01228718 0,02222772 ! DNA replication initiation GO:0006270 14 14 0,000 0,01228718 0,02221647 ! T cell differentiation in the thymus GO:0033077 18 14 0,000 0,01228718 0,02220522 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01228718 0,02219399 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01228718 0,02218277 ! calcium activated cation channel activity GO:0005227 16 14 0,000 0,01228718 0,02217156 ! sulfuric ester hydrolase activity GO:0008484 15 14 0,000 0,01228718 0,02216036 ! serotonin receptor activity GO:0004993 14 14 0,000 0,01228718 0,02214918 ! positive regulation of bone mineralization GO:0030501 15 14 0,000 0,01228718 0,022138 ! synaptic transmission, cholinergic GO:0007271 15 14 0,000 0,01228718 0,02212684 ! dopamine metabolic process GO:0042417 17 14 0,000 0,01228718 0,02211569 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01228718 0,02210455 ! ion gated channel activity GO:0022839 16 14 0,000 0,01228718 0,02209342 ! male genitalia development GO:0030539 14 14 0,000 0,01228718 0,0220823 ! regulation of axon extension GO:0030516 15 14 0,000 0,01228718 0,02207119 ! regulation of BMP signaling pathway GO:0030510 14 14 0,000 0,01228718 0,02206009 ! estrogen receptor signaling pathway GO:0030520 14 14 0,000 0,01228718 0,02204901 ! interleukin-1 receptor binding GO:0005149 14 14 0,000 0,01228718 0,02203793 ! defense response to virus GO:0051607 19 14 0,000 0,01228718 0,02202687 ! cadherin binding GO:0045296 16 14 0,000 0,01228718 0,02201582 ! negative regulation of hormone secretion GO:0046888 16 15 0,000 0,01315948 0,02356696 ! nuclear replication fork GO:0043596 16 15 0,000 0,01315948 0,02355514 ! skin development GO:0043588 16 15 0,000 0,01315948 0,02354334 ! phosphoinositide phosphorylation GO:0046854 16 15 0,000 0,01315948 0,02353155 GO:0046834|lipid phosphorylation, ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01315948 0,02351977 ! cardiac muscle contraction GO:0060048 16 15 0,000 0,01315948 0,02350801 ! polysome GO:0005844 16 15 0,000 0,01315948 0,02349625 ! negative regulation of peptidase activity GO:0010466 16 15 0,000 0,01315948 0,02348451 ! mitotic chromosome condensation GO:0007076 15 15 0,000 0,01315948 0,02347278 ! regulation of survival gene product expression GO:0045884 15 15 0,000 0,01315948 0,02346106 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 15 0,000 0,01315948 0,02344936 ! glycoprotein catabolic process GO:0006516 15 15 0,000 0,01315948 0,02343766 ! DNA duplex unwinding GO:0032508 15 15 0,000 0,01315948 0,02342598 GO:0032392|DNA geometric change, ! glutamine metabolic process GO:0006541 16 15 0,000 0,01315948 0,0234143 ! proton-transporting V-type ATPase complex GO:0033176 15 15 0,000 0,01315948 0,02340264 ! response to vitamin A GO:0033189 15 15 0,000 0,01315948 0,02339099 ! protease binding GO:0002020 16 15 0,000 0,01315948 0,02337936 ! regulation of ion transmembrane transporter activity GO:0032412 15 15 0,000 0,01315948 0,02336773 ! actin filament bundle formation GO:0051017 15 15 0,000 0,01315948 0,02335612 ! calcium ion-dependent exocytosis GO:0017156 15 15 0,000 0,01315948 0,02334451 ! purine nucleoside monophosphate metabolic process GO:0009126 16 15 0,000 0,01315948 0,02333292 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 15 15 0,000 0,01315948 0,02332134 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01315948 0,02330978 ! positive regulation of biomineral formation GO:0070169 16 15 0,000 0,01315948 0,02329822 ! positive regulation of oxidoreductase activity GO:0051353 15 15 0,000 0,01315948 0,02328667 ! filopodium GO:0030175 15 15 0,000 0,01315948 0,02327514 ! negative regulation of inflammatory response GO:0050728 15 15 0,000 0,01315948 0,02326362 ! positive regulation of transmission of nerve impulse GO:0051971 15 15 0,000 0,01315948 0,02325211 ! branched chain family amino acid metabolic process GO:0009081 15 15 0,000 0,01315948 0,02324061 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01315948 0,02322912 ! heme biosynthetic process GO:0006783 15 15 0,000 0,01315948 0,02321764 ! SMAD binding GO:0046332 16 15 0,000 0,01315948 0,02320618 ! nerve development GO:0021675 16 15 0,000 0,01315948 0,02319472 ! epithelial to mesenchymal transition GO:0001837 16 15 0,000 0,01315948 0,02318328 ! mannose binding GO:0005537 15 15 0,000 0,01315948 0,02317185 ! phosphoprotein binding GO:0051219 17 15 0,000 0,01315948 0,02316043 ! mismatched DNA binding GO:0030983 15 15 0,000 0,01315948 0,02314902 ! antigen receptor-mediated signaling pathway GO:0050851 21 15 0,000 0,01315948 0,02313762 ! regulation of skeletal muscle tissue development GO:0048641 15 15 0,000 0,01315948 0,02312623 ! synaptonemal complex GO:0000795 15 15 0,000 0,01315948 0,02311486 ! N-terminal protein amino acid modification GO:0031365 16 15 0,000 0,01315948 0,02310349 ! positive regulation of protein complex assembly GO:0031334 15 15 0,000 0,01315948 0,02309214 ! water transport GO:0006833 15 15 0,000 0,01315948 0,0230808 GO:0042044|fluid transport, ! phosphatidylinositol metabolic process GO:0046488 16 15 0,000 0,01315948 0,02306947 ! viral genome replication GO:0019079 15 15 0,000 0,01315948 0,02305815 ! phosphatidylcholine metabolic process GO:0046470 17 15 0,000 0,01315948 0,02304684 ! inositol metabolic process GO:0006020 15 15 0,000 0,01315948 0,02303554 ! sulfate transport GO:0008272 15 15 0,000 0,01315948 0,02302426 ! protein-lipid complex GO:0032994 15 15 0,000 0,01315948 0,02301298 GO:0034358|plasma lipoprotein particle, ! positive regulation of ion transport GO:0043270 18 15 0,000 0,01315948 0,02300172 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 15 15 0,000 0,01315948 0,02299046 ! heart looping GO:0001947 15 15 0,000 0,01315948 0,02297922 ! isoprenoid biosynthetic process GO:0008299 16 15 0,000 0,01315948 0,02296799 ! protein histidine kinase activity GO:0004673 16 15 0,000 0,01315948 0,02295677 GO:0000155|two-component sensor activity, ! cardiac muscle tissue development GO:0048738 15 15 0,000 0,01315948 0,02294556 ! regulation of striated muscle contraction GO:0006942 16 15 0,000 0,01315948 0,02293436 ! response to osmotic stress GO:0006970 16 15 0,000 0,01315948 0,02292317 ! fructose metabolic process GO:0006000 15 15 0,000 0,01315948 0,022912 ! vesicle coating GO:0006901 16 15 0,000 0,01315948 0,02290083 ! DNA integration GO:0015074 16 15 0,000 0,01315948 0,02288968 ! alcohol binding GO:0043178 16 15 0,000 0,01315948 0,02287853 ! disulfide oxidoreductase activity GO:0015036 15 15 0,000 0,01315948 0,0228674 ! intermediate filament cytoskeleton organization GO:0045104 16 15 0,000 0,01315948 0,02285628 ! regulation of vasodilation GO:0042312 15 15 0,000 0,01315948 0,02284517 ! genitalia development GO:0048806 15 15 0,000 0,01315948 0,02283407 ! structural constituent of eye lens GO:0005212 15 15 0,000 0,01315948 0,02282298 ! regulation of monooxygenase activity GO:0032768 15 15 0,000 0,01315948 0,0228119 ! voltage-gated sodium channel activity GO:0005248 17 15 0,000 0,01315948 0,02280083 ! ribonucleoprotein binding GO:0043021 16 15 0,000 0,01315948 0,02278977 ! proton-transporting ATP synthase complex GO:0045259 15 15 0,000 0,01315948 0,02277872 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 15 15 0,000 0,01315948 0,02276769 ! regulation of immunoglobulin production GO:0002637 19 15 0,000 0,01315948 0,02275666 ! retinoic acid receptor activity GO:0003708 15 15 0,000 0,01315948 0,02274565 ! receptor activator activity GO:0030546 15 15 0,000 0,01315948 0,02273464 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 15 15 0,000 0,01315948 0,02272365 ! protein transmembrane transporter activity GO:0008320 15 15 0,000 0,01315948 0,02271267 ! histone binding GO:0042393 15 15 0,000 0,01315948 0,02270169 ! phosphoinositide 3-kinase activity GO:0035004 16 15 0,000 0,01315948 0,02269073 ! sialyltransferase activity GO:0008373 15 15 0,000 0,01315948 0,02267978 ! platelet-derived growth factor receptor binding GO:0005161 16 15 0,000 0,01315948 0,02266884 ! drug transporter activity GO:0015238 15 15 0,000 0,01315948 0,02265791 ! negative regulation of homeostatic process GO:0032845 15 15 0,000 0,01315948 0,02264699 ! phosphoinositide 3-kinase complex GO:0005942 16 15 0,000 0,01315948 0,02263608 ! binding of sperm to zona pellucida GO:0007339 16 15 0,000 0,01315948 0,02262518 ! peptide hormone processing GO:0016486 17 15 0,000 0,01315948 0,0226143 ! aldo-keto reductase activity GO:0004033 15 15 0,000 0,01315948 0,02260342 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01315948 0,02259255 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 16 16 0,000 0,01403107 0,02407734 ! positive regulation of cell size GO:0045793 16 16 0,000 0,01403107 0,02406578 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01403107 0,02405423 ! positive regulation of hormone secretion GO:0046887 17 16 0,000 0,01403107 0,02404268 ! protein amino acid ADP-ribosylation GO:0006471 18 16 0,000 0,01403107 0,02403115 ! response to vitamin GO:0033273 16 16 0,000 0,01403107 0,02401963 ! gene silencing by RNA GO:0031047 16 16 0,000 0,01403107 0,02400812 ! regulation of postsynaptic membrane potential GO:0060078 18 16 0,000 0,01403107 0,02399663 ! kinesin complex GO:0005871 16 16 0,000 0,01403107 0,02398514 ! cornified envelope GO:0001533 18 16 0,000 0,01403107 0,02397366 ! regulation of transmembrane transporter activity GO:0022898 16 16 0,000 0,01403107 0,0239622 GO:0032409|regulation of transporter activity, ! negative regulation of epithelial cell proliferation GO:0050680 17 16 0,000 0,01403107 0,02395074 ! pyrimidine ribonucleotide metabolic process GO:0009218 18 16 0,000 0,01403107 0,0239393 ! pituitary gland development GO:0021983 16 16 0,000 0,01403107 0,02392787 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 18 16 0,000 0,01403107 0,02391645 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 19 16 0,000 0,01403107 0,02390504 ! cell-substrate junction assembly GO:0007044 18 16 0,000 0,01403107 0,02389364 ! peptidyl-serine phosphorylation GO:0018105 16 16 0,000 0,01403107 0,02388225 ! branching involved in ureteric bud morphogenesis GO:0001658 16 16 0,000 0,01403107 0,02387087 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 16 16 0,000 0,01403107 0,0238595 ! nucleobase metabolic process GO:0009112 19 16 0,000 0,01403107 0,02384815 ! beta-catenin binding GO:0008013 17 16 0,000 0,01403107 0,0238368 ! regulation of steroid metabolic process GO:0019218 17 16 0,000 0,01403107 0,02382547 ! neuron recognition GO:0008038 17 16 0,000 0,01403107 0,02381414 ! oogenesis GO:0048477 19 16 0,000 0,01403107 0,02380283 ! low-density lipoprotein binding GO:0030169 17 16 0,000 0,01403107 0,02379153 ! clathrin vesicle coat GO:0030125 19 16 0,000 0,01403107 0,02378023 ! COPI-coated vesicle GO:0030137 16 16 0,000 0,01403107 0,02376895 ! sphingolipid biosynthetic process GO:0030148 16 16 0,000 0,01403107 0,02375768 ! biomineral formation GO:0031214 16 16 0,000 0,01403107 0,02374642 ! vitamin transport GO:0051180 16 16 0,000 0,01403107 0,02373518 ! folic acid and derivative metabolic process GO:0006760 16 16 0,000 0,01403107 0,02372394 ! organic cation transport GO:0015695 16 16 0,000 0,01403107 0,02371271 ! proximal/distal pattern formation GO:0009954 16 16 0,000 0,01403107 0,02370149 ! regulation of glucose import GO:0046324 17 16 0,000 0,01403107 0,02369029 GO:0010827|regulation of glucose transport, ! aromatic compound biosynthetic process GO:0019438 17 16 0,000 0,01403107 0,02367909 ! aromatic compound catabolic process GO:0019439 18 16 0,000 0,01403107 0,0236679 ! negative regulation of coagulation GO:0050819 18 16 0,000 0,01403107 0,02365673 ! tRNA binding GO:0000049 16 16 0,000 0,01403107 0,02364557 ! regulation of cell killing GO:0031341 20 16 0,000 0,01403107 0,02363441 ! negative regulation of defense response GO:0031348 16 16 0,000 0,01403107 0,02362327 ! regulation of neuronal synaptic plasticity GO:0048168 16 16 0,000 0,01403107 0,02361214 ! hindlimb morphogenesis GO:0035137 16 16 0,000 0,01403107 0,02360101 ! bile acid metabolic process GO:0008206 16 16 0,000 0,01403107 0,0235899 ! axis specification GO:0009798 16 16 0,000 0,01403107 0,0235788 ! adult walking behavior GO:0007628 17 16 0,000 0,01403107 0,02356771 ! C-C chemokine binding GO:0019957 16 16 0,000 0,01403107 0,02355663 GO:0016493|C-C chemokine receptor activity, ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 18 16 0,000 0,01403107 0,02354556 ! protein phosphatase binding GO:0019903 17 16 0,000 0,01403107 0,0235345 ! epidermis morphogenesis GO:0048730 16 16 0,000 0,01403107 0,02352345 ! acyl-CoA dehydrogenase activity GO:0003995 16 16 0,000 0,01403107 0,02351241 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01403107 0,02350139 ! SH2 domain binding GO:0042169 19 16 0,000 0,01403107 0,02349037 ! UDP-galactosyltransferase activity GO:0035250 17 16 0,000 0,01403107 0,02347936 ! RNA methyltransferase activity GO:0008173 16 16 0,000 0,01403107 0,02346836 ! neutral amino acid transport GO:0015804 16 16 0,000 0,01403107 0,02345738 ! glucuronosyltransferase activity GO:0015020 17 16 0,000 0,01403107 0,0234464 ! regulation of alpha-beta T cell differentiation GO:0046637 16 16 0,000 0,01403107 0,02343543 ! cellular pigmentation GO:0033059 16 16 0,000 0,01403107 0,02342448 ! mannosidase activity GO:0015923 19 16 0,000 0,01403107 0,02341353 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 16 16 0,000 0,01403107 0,02340259 ! negative regulation of tissue remodeling GO:0034104 16 16 0,000 0,01403107 0,02339167 ! positive regulation of neurological system process GO:0031646 16 16 0,000 0,01403107 0,02338075 ! neuromuscular synaptic transmission GO:0007274 16 16 0,000 0,01403107 0,02336985 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01403107 0,02335895 ! sperm-egg recognition GO:0035036 17 16 0,000 0,01403107 0,02334807 ! axoneme GO:0005930 16 16 0,000 0,01403107 0,02333719 ! anion exchanger activity GO:0015380 18 17 0,000 0,01490195 0,02477414 ! neuron maturation GO:0042551 18 17 0,000 0,01490195 0,02476262 ! metencephalon development GO:0022037 18 17 0,000 0,01490195 0,0247511 ! reciprocal meiotic recombination GO:0007131 17 17 0,000 0,01490195 0,02473959 ! hemoglobin complex GO:0005833 18 17 0,000 0,01490195 0,0247281 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 17 17 0,000 0,01490195 0,02471661 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 17 17 0,000 0,01490195 0,02470514 ! protein amino acid deacetylation GO:0006476 17 17 0,000 0,01490195 0,02469367 ! protein amino acid acetylation GO:0006473 19 17 0,000 0,01490195 0,02468222 ! positive regulation of nucleocytoplasmic transport GO:0046824 18 17 0,000 0,01490195 0,02467078 ! regulation of neurotransmitter secretion GO:0046928 18 17 0,000 0,01490195 0,02465934 ! striated muscle thick filament GO:0005863 19 17 0,000 0,01490195 0,02464792 GO:0032982|myosin filament, ! gamma-aminobutyric acid signaling pathway GO:0007214 17 17 0,000 0,01490195 0,02463651 ! glial cell development GO:0021782 17 17 0,000 0,01490195 0,02462511 ! regulation of muscle cell differentiation GO:0051147 17 17 0,000 0,01490195 0,02461372 ! pancreas development GO:0031016 17 17 0,000 0,01490195 0,02460234 ! acetylcholine receptor activity GO:0015464 17 17 0,000 0,01490195 0,02459097 ! nuclear heterochromatin GO:0005720 18 17 0,000 0,01490195 0,02457961 ! calcium-dependent protein binding GO:0048306 19 17 0,000 0,01490195 0,02456827 ! cerebral cortex development GO:0021987 17 17 0,000 0,01490195 0,02455693 ! cellular response to starvation GO:0009267 18 17 0,000 0,01490195 0,0245456 ! signal sequence binding GO:0005048 17 17 0,000 0,01490195 0,02453428 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 17 17 0,000 0,01490195 0,02452298 ! cellular macromolecular complex disassembly GO:0034623 18 17 0,000 0,01490195 0,02451168 ! transforming growth factor beta receptor activity GO:0005024 17 17 0,000 0,01490195 0,0245004 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01490195 0,02448912 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 17 17 0,000 0,01490195 0,02447786 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 17 0,000 0,01490195 0,0244666 ! actin filament bundle GO:0032432 17 17 0,000 0,01490195 0,02445536 GO:0001725|stress fiber, ! small nucleolar ribonucleoprotein complex GO:0005732 17 17 0,000 0,01490195 0,02444413 ! response to lipopolysaccharide GO:0032496 17 17 0,000 0,01490195 0,0244329 ! plasma membrane fusion GO:0045026 18 17 0,000 0,01490195 0,02442169 ! regulation of protein binding GO:0043393 18 17 0,000 0,01490195 0,02441049 ! recycling endosome GO:0055037 18 17 0,000 0,01490195 0,0243993 ! prostaglandin metabolic process GO:0006693 18 17 0,000 0,01490195 0,02438811 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 19 17 0,000 0,01490195 0,02437694 ! regulation of Rho GTPase activity GO:0032319 17 17 0,000 0,01490195 0,02436578 ! regulation of immunoglobulin mediated immune response GO:0002889 21 17 0,000 0,01490195 0,02435463 GO:0002712|regulation of B cell mediated immunity, ! receptor signaling complex scaffold activity GO:0030159 17 17 0,000 0,01490195 0,02434349 ! positive regulation of cytokine secretion GO:0050715 17 17 0,000 0,01490195 0,02433236 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 17 0,000 0,01490195 0,02432124 ! endodeoxyribonuclease activity GO:0004520 17 17 0,000 0,01490195 0,02431012 ! sphingolipid catabolic process GO:0030149 18 17 0,000 0,01490195 0,02429902 ! steroid catabolic process GO:0006706 17 17 0,000 0,01490195 0,02428793 ! oxygen transport GO:0015671 18 17 0,000 0,01490195 0,02427685 GO:0005344|oxygen transporter activity, ! phosphatidylinositol binding GO:0005545 19 17 0,000 0,01490195 0,02426578 ! hyaluronic acid binding GO:0005540 17 17 0,000 0,01490195 0,02425472 ! negative regulation of T cell activation GO:0050868 17 17 0,000 0,01490195 0,02424367 ! regulation of glucose metabolic process GO:0010906 17 17 0,000 0,01490195 0,02423263 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 17 17 0,000 0,01490195 0,0242216 ! glycosaminoglycan biosynthetic process GO:0006024 17 17 0,000 0,01490195 0,02421058 ! MAP kinase kinase kinase activity GO:0004709 18 17 0,000 0,01490195 0,02419957 ! L-ascorbic acid binding GO:0031418 17 17 0,000 0,01490195 0,02418857 ! negative regulation of endothelial cell proliferation GO:0001937 17 17 0,000 0,01490195 0,02417758 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 18 17 0,000 0,01490195 0,0241666 ! photoreceptor cell maintenance GO:0045494 17 17 0,000 0,01490195 0,02415563 ! response to carbohydrate stimulus GO:0009743 17 17 0,000 0,01490195 0,02414467 ! calmodulin-dependent protein kinase activity GO:0004683 19 17 0,000 0,01490195 0,02413372 ! fucose metabolic process GO:0006004 19 17 0,000 0,01490195 0,02412278 ! D-ribose metabolic process GO:0006014 18 17 0,000 0,01490195 0,02411185 ! membrane budding GO:0006900 18 17 0,000 0,01490195 0,02410093 ! AMP binding GO:0016208 17 17 0,000 0,01490195 0,02409002 ! body fluid secretion GO:0007589 18 17 0,000 0,01490195 0,02407912 ! response to fungus GO:0009620 17 17 0,000 0,01490195 0,02406823 ! positive regulation of alpha-beta T cell activation GO:0046635 21 17 0,000 0,01490195 0,02405735 ! intermediate filament-based process GO:0045103 18 17 0,000 0,01490195 0,02404648 ! rRNA binding GO:0019843 17 17 0,000 0,01490195 0,02403562 ! nucleotide-excision repair, DNA gap filling GO:0006297 18 17 0,000 0,01490195 0,02402477 ! regulation of interleukin-2 production GO:0032663 17 17 0,000 0,01490195 0,02401393 ! voltage-gated chloride channel activity GO:0005247 17 17 0,000 0,01490195 0,0240031 ! DNA fragmentation involved in apoptosis GO:0006309 17 17 0,000 0,01490195 0,02399227 ! neutrophil chemotaxis GO:0030593 18 17 0,000 0,01490195 0,02398146 ! long-chain fatty acid transport GO:0015909 17 17 0,000 0,01490195 0,02397066 ! tissue regeneration GO:0042246 17 17 0,000 0,01490195 0,02395987 ! detection of biotic stimulus GO:0009595 18 17 0,000 0,01490195 0,02394908 ! muscle maintenance GO:0046716 18 17 0,000 0,01490195 0,02393831 ! cell-cell junction organization GO:0045216 17 17 0,000 0,01490195 0,02392755 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 17 17 0,000 0,01490195 0,02391679 ! somatic recombination of immunoglobulin gene segments GO:0016447 17 17 0,000 0,01490195 0,02390605 ! cell-cell adherens junction GO:0005913 17 17 0,000 0,01490195 0,02389531 ! triacylglycerol lipase activity GO:0004806 17 17 0,000 0,01490195 0,02388459 ! ATP-dependent DNA helicase activity GO:0004003 17 17 0,000 0,01490195 0,02387387 ! chaperone binding GO:0051087 18 18 0,000 0,01577212 0,02525661 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01577212 0,02524529 ! pteridine and derivative metabolic process GO:0042558 19 18 0,000 0,01577212 0,02523398 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01577212 0,02522268 GO:0005763|mitochondrial small ribosomal subunit, ! signal complex assembly GO:0007172 18 18 0,000 0,01577212 0,02521139 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 19 18 0,000 0,01577212 0,02520011 ! limbic system development GO:0021761 18 18 0,000 0,01577212 0,02518884 ! cellular response to hydrogen peroxide GO:0070301 18 18 0,000 0,01577212 0,02517758 GO:0042744|hydrogen peroxide catabolic process, ! MHC class II protein complex GO:0042613 18 18 0,000 0,01577212 0,02516633 ! positive regulation of proteolysis GO:0045862 19 18 0,000 0,01577212 0,02515509 ! deoxyribonucleotide metabolic process GO:0009262 19 18 0,000 0,01577212 0,02514386 ! lysosome organization GO:0007040 18 18 0,000 0,01577212 0,02513264 ! central nervous system neuron development GO:0021954 19 18 0,000 0,01577212 0,02512143 ! fatty acid beta-oxidation GO:0006635 18 18 0,000 0,01577212 0,02511023 ! peptide cross-linking GO:0018149 20 18 0,000 0,01577212 0,02509904 ! ventricular cardiac muscle morphogenesis GO:0055010 19 18 0,000 0,01577212 0,02508786 ! presynaptic membrane GO:0042734 19 18 0,000 0,01577212 0,02507669 ! embryonic digit morphogenesis GO:0042733 20 18 0,000 0,01577212 0,02506553 ! neural crest cell migration GO:0001755 18 18 0,000 0,01577212 0,02505438 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01577212 0,02504324 ! positive regulation of adaptive immune response GO:0002821 22 18 0,000 0,01577212 0,0250321 ! positive regulation of intracellular transport GO:0032388 19 18 0,000 0,01577212 0,02502098 ! negative regulation of intracellular transport GO:0032387 18 18 0,000 0,01577212 0,02500987 ! peptidyl-serine modification GO:0018209 18 18 0,000 0,01577212 0,02499877 ! cell-cell recognition GO:0009988 19 18 0,000 0,01577212 0,02498768 ! vitamin D receptor binding GO:0042809 19 18 0,000 0,01577212 0,0249766 ! porphyrin biosynthetic process GO:0006779 18 18 0,000 0,01577212 0,02496553 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 18 0,000 0,01577212 0,02495447 ! actin filament-based movement GO:0030048 18 18 0,000 0,01577212 0,02494342 ! negative regulation of translation GO:0017148 20 18 0,000 0,01577212 0,02493238 ! Rab GTPase binding GO:0017137 18 18 0,000 0,01577212 0,02492134 ! histone deacetylase activity GO:0004407 19 18 0,000 0,01577212 0,02491032 GO:0033558|protein deacetylase activity, ! protein import into nucleus, docking GO:0000059 18 18 0,000 0,01577212 0,02489931 ! glycerol metabolic process GO:0006071 19 18 0,000 0,01577212 0,02488831 ! post-Golgi vesicle-mediated transport GO:0006892 18 18 0,000 0,01577212 0,02487731 ! intra-Golgi vesicle-mediated transport GO:0006891 18 18 0,000 0,01577212 0,02486633 ! aminoglycan catabolic process GO:0006026 18 18 0,000 0,01577212 0,02485536 ! aminoglycan biosynthetic process GO:0006023 18 18 0,000 0,01577212 0,02484439 ! memory GO:0007613 19 18 0,000 0,01577212 0,02483344 ! C21-steroid hormone metabolic process GO:0008207 18 18 0,000 0,01577212 0,02482249 ! regulation of DNA recombination GO:0000018 22 18 0,000 0,01577212 0,02481156 ! protein phosphatase type 2A complex GO:0000159 20 18 0,000 0,01577212 0,02480063 ! inactivation of MAPK activity GO:0000188 19 18 0,000 0,01577212 0,02478972 ! pigmentation during development GO:0048066 21 18 0,000 0,01577212 0,02477881 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 18 0,000 0,01577212 0,02476791 ! acetylcholine binding GO:0042166 19 18 0,000 0,01577212 0,02475703 ! neurotransmitter:sodium symporter activity GO:0005328 18 18 0,000 0,01577212 0,02474615 ! neurotransmitter metabolic process GO:0042133 23 18 0,000 0,01577212 0,02473528 ! neuromuscular junction development GO:0007528 21 18 0,000 0,01577212 0,02472442 ! nonmotile primary cilium GO:0031513 19 18 0,000 0,01577212 0,02471357 ! coreceptor activity GO:0015026 18 18 0,000 0,01577212 0,02470274 ! behavioral interaction between organisms GO:0051705 18 18 0,000 0,01577212 0,02469191 ! carbonate dehydratase activity GO:0004089 19 18 0,000 0,01577212 0,02468109 ! cytolysis GO:0019835 18 18 0,000 0,01577212 0,02467027 ! phosphate binding GO:0042301 19 18 0,000 0,01577212 0,02465947 ! transport vesicle membrane GO:0030658 21 18 0,000 0,01577212 0,02464868 ! specific transcriptional repressor activity GO:0016566 18 18 0,000 0,01577212 0,0246379 ! DNA modification GO:0006304 20 18 0,000 0,01577212 0,02462713 ! bicarbonate transmembrane transporter activity GO:0015106 19 18 0,000 0,01577212 0,02461636 ! detection of chemical stimulus GO:0009593 19 18 0,000 0,01577212 0,02460561 ! ionotropic glutamate receptor activity GO:0004970 20 18 0,000 0,01577212 0,02459486 ! aspartic-type endopeptidase activity GO:0004190 19 18 0,000 0,01577212 0,02458413 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 18 18 0,000 0,01577212 0,0245734 ! 3'-5' exonuclease activity GO:0008408 18 18 0,000 0,01577212 0,02456268 ! RNA polymerase II transcription mediator activity GO:0016455 19 18 0,000 0,01577212 0,02455198 ! water-soluble vitamin biosynthetic process GO:0042364 19 18 0,000 0,01577212 0,02454128 ! connexon complex GO:0005922 18 18 0,000 0,01577212 0,02453059 ! solute:hydrogen antiporter activity GO:0015299 18 18 0,000 0,01577212 0,02451991 ! mRNA export from nucleus GO:0006406 21 19 0,000 0,01664158 0,02586035 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 20 19 0,000 0,01664158 0,0258491 ! regulation of interferon-gamma production GO:0032649 20 19 0,000 0,01664158 0,02583786 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 20 19 0,000 0,01664158 0,02582663 ! anion:anion antiporter activity GO:0015301 20 19 0,000 0,01664158 0,02581541 ! cAMP metabolic process GO:0046058 19 19 0,000 0,01664158 0,0258042 ! spindle microtubule GO:0005876 20 19 0,000 0,01664158 0,025793 ! ovarian follicle development GO:0001541 19 19 0,000 0,01664158 0,02578181 ! retinoid metabolic process GO:0001523 19 19 0,000 0,01664158 0,02577063 GO:0016101|diterpenoid metabolic process, ! caspase activator activity GO:0008656 19 19 0,000 0,01664158 0,02575946 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 21 19 0,000 0,01664158 0,0257483 ! vacuolar transport GO:0007034 19 19 0,000 0,01664158 0,02573715 ! threonine-type endopeptidase activity GO:0004298 19 19 0,000 0,01664158 0,02572601 GO:0070003|threonine-type peptidase activity, ! myofibril assembly GO:0030239 19 19 0,000 0,01664158 0,02571487 GO:0055002|striated muscle cell development, ! monocarboxylic acid transmembrane transporter activity GO:0008028 20 19 0,000 0,01664158 0,02570375 ! positive regulation of multicellular organism growth GO:0040018 19 19 0,000 0,01664158 0,02569264 ! cell projection membrane GO:0031253 20 19 0,000 0,01664158 0,02568154 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01664158 0,02567044 ! transcriptional repressor complex GO:0017053 19 19 0,000 0,01664158 0,02565936 ! vitamin A metabolic process GO:0006776 19 19 0,000 0,01664158 0,02564828 ! positive regulation of myeloid cell differentiation GO:0045639 20 19 0,000 0,01664158 0,02563722 ! negative regulation of myeloid cell differentiation GO:0045638 19 19 0,000 0,01664158 0,02562616 ! glutamine family amino acid catabolic process GO:0009065 21 19 0,000 0,01664158 0,02561512 ! leukotriene biosynthetic process GO:0019370 19 19 0,000 0,01664158 0,02560408 GO:0043450|alkene biosynthetic process, ! gas transport GO:0015669 20 19 0,000 0,01664158 0,02559306 ! retinoid binding GO:0005501 19 19 0,000 0,01664158 0,02558204 GO:0019840|isoprenoid binding, ! peptide hormone secretion GO:0030072 20 19 0,000 0,01664158 0,02557103 ! protein stabilization GO:0050821 20 19 0,000 0,01664158 0,02556003 ! cellular monovalent inorganic cation homeostasis GO:0030004 20 19 0,000 0,01664158 0,02554904 ! myeloid leukocyte differentiation GO:0002573 21 19 0,000 0,01664158 0,02553806 ! microtubule-based transport GO:0010970 19 19 0,000 0,01664158 0,02552709 ! protein complex scaffold GO:0032947 19 19 0,000 0,01664158 0,02551613 ! SNAP receptor activity GO:0005484 21 19 0,000 0,01664158 0,02550518 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01664158 0,02549424 GO:0006479|protein amino acid methylation, ! regulation of systemic arterial blood pressure by hormone GO:0001990 19 19 0,000 0,01664158 0,02548331 GO:0050886|endocrine process, ! visual behavior GO:0007632 22 19 0,000 0,01664158 0,02547239 GO:0008542|visual learning, ! 4 iron, 4 sulfur cluster binding GO:0051539 21 19 0,000 0,01664158 0,02546147 ! glycoprotein binding GO:0001948 23 19 0,000 0,01664158 0,02545057 ! sensory perception of taste GO:0050909 19 19 0,000 0,01664158 0,02543967 ! myoblast differentiation GO:0045445 19 19 0,000 0,01664158 0,02542879 ! cell differentiation in spinal cord GO:0021515 19 19 0,000 0,01664158 0,02541791 ! immune response-activating cell surface receptor signaling pathway GO:0002429 25 19 0,000 0,01664158 0,02540704 ! myosin binding GO:0017022 19 19 0,000 0,01664158 0,02539619 ! organic acid:sodium symporter activity GO:0005343 19 19 0,000 0,01664158 0,02538534 ! cell aging GO:0007569 19 19 0,000 0,01664158 0,0253745 ! stem cell differentiation GO:0048863 19 19 0,000 0,01664158 0,02536367 ! regulation of myeloid leukocyte differentiation GO:0002761 21 19 0,000 0,01664158 0,02535285 ! heart process GO:0003015 20 19 0,000 0,01664158 0,02534204 GO:0060047|heart contraction, ! mismatch repair GO:0006298 19 19 0,000 0,01664158 0,02533123 ! secretory granule membrane GO:0030667 20 19 0,000 0,01664158 0,02532044 ! MHC protein binding GO:0042287 19 19 0,000 0,01664158 0,02530966 ! extracellular-glutamate-gated ion channel activity GO:0005234 21 19 0,000 0,01664158 0,02529888 ! chloride transmembrane transporter activity GO:0015108 20 19 0,000 0,01664158 0,02528812 ! GABA-A receptor activity GO:0004890 20 19 0,000 0,01664158 0,02527736 ! response to cytokine stimulus GO:0034097 20 19 0,000 0,01664158 0,02526661 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01664158 0,02525588 ! translation elongation factor activity GO:0003746 22 19 0,000 0,01664158 0,02524515 ! insulin receptor binding GO:0005158 20 19 0,000 0,01664158 0,02523443 ! phosphoprotein phosphatase inhibitor activity GO:0004864 21 19 0,000 0,01664158 0,02522372 ! protein secretion GO:0009306 20 20 0,000 0,01751033 0,02652922 ! positive regulation of angiogenesis GO:0045766 22 20 0,000 0,01751033 0,02651797 ! proteasome core complex GO:0005839 20 20 0,000 0,01751033 0,02650673 ! positive regulation of bone remodeling GO:0046852 21 20 0,000 0,01751033 0,0264955 ! heterophilic cell adhesion GO:0007157 21 20 0,000 0,01751033 0,02648428 ! glutathione transferase activity GO:0004364 20 20 0,000 0,01751033 0,02647307 ! positive regulation of endocytosis GO:0045807 20 20 0,000 0,01751033 0,02646186 ! actomyosin GO:0042641 20 20 0,000 0,01751033 0,02645067 ! positive regulation of innate immune response GO:0045089 20 20 0,000 0,01751033 0,02643949 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 20 0,000 0,01751033 0,02642831 ! vacuole organization GO:0007033 20 20 0,000 0,01751033 0,02641715 ! oxidoreductase activity, acting on heme group of donors GO:0016675 21 20 0,000 0,01751033 0,02640599 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! purine ribonucleoside metabolic process GO:0046128 23 20 0,000 0,01751033 0,02639484 GO:0042278|purine nucleoside metabolic process, ! regulation of exocytosis GO:0017157 21 20 0,000 0,01751033 0,02638371 ! vitamin biosynthetic process GO:0009110 21 20 0,000 0,01751033 0,02637258 ! glycosphingolipid metabolic process GO:0006687 20 20 0,000 0,01751033 0,02636146 ! kinase activator activity GO:0019209 20 20 0,000 0,01751033 0,02635035 ! diencephalon development GO:0021536 20 20 0,000 0,01751033 0,02633925 ! nuclear inner membrane GO:0005637 20 20 0,000 0,01751033 0,02632816 ! positive regulation of locomotion GO:0040017 20 20 0,000 0,01751033 0,02631708 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! synaptic vesicle transport GO:0048489 21 20 0,000 0,01751033 0,02630601 ! proteoglycan biosynthetic process GO:0030166 20 20 0,000 0,01751033 0,02629495 ! leukocyte homeostasis GO:0001776 22 20 0,000 0,01751033 0,02628389 ! regulation of blood coagulation GO:0030193 22 20 0,000 0,01751033 0,02627285 ! positive regulation of osteoblast differentiation GO:0045669 22 20 0,000 0,01751033 0,02626182 ! regulation of generation of precursor metabolites and energy GO:0043467 21 20 0,000 0,01751033 0,02625079 ! ligase activity, forming carbon-sulfur bonds GO:0016877 20 20 0,000 0,01751033 0,02623977 ! phosphorus-oxygen lyase activity GO:0016849 20 20 0,000 0,01751033 0,02622877 ! embryonic organ morphogenesis GO:0048562 22 20 0,000 0,01751033 0,02621777 ! alditol metabolic process GO:0019400 21 20 0,000 0,01751033 0,02620678 ! liver development GO:0001889 20 20 0,000 0,01751033 0,0261958 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 20 0,000 0,01751033 0,02618483 ! chromosome, telomeric region GO:0000781 21 20 0,000 0,01751033 0,02617387 ! calcium-independent cell-cell adhesion GO:0016338 20 20 0,000 0,01751033 0,02616292 ! response to alkaloid GO:0043279 22 20 0,000 0,01751033 0,02615198 ! regulation of cell-matrix adhesion GO:0001952 22 20 0,000 0,01751033 0,02614105 GO:0010810|regulation of cell-substrate adhesion, ! transmembrane receptor protein phosphatase activity GO:0019198 27 20 0,000 0,01751033 0,02613012 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! smooth muscle contraction GO:0006939 21 20 0,000 0,01751033 0,02611921 ! heme metabolic process GO:0042168 22 20 0,000 0,01751033 0,0261083 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0,000 0,01751033 0,0260974 ! sex determination GO:0007530 20 20 0,000 0,01751033 0,02608652 ! negative regulation of protein catabolic process GO:0042177 21 20 0,000 0,01751033 0,02607564 ! peptide secretion GO:0002790 21 20 0,000 0,01751033 0,02606477 ! regulation of alpha-beta T cell activation GO:0046634 24 20 0,000 0,01751033 0,02605391 ! interaction with host GO:0051701 24 20 0,000 0,01751033 0,02604306 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 26 20 0,000 0,01751033 0,02603222 ! vasodilation GO:0042311 21 20 0,000 0,01751033 0,02602138 ! regulation of tumor necrosis factor production GO:0032680 20 20 0,000 0,01751033 0,02601056 ! regulation of chromosome organization GO:0033044 20 20 0,000 0,01751033 0,02599974 ! inward rectifier potassium channel activity GO:0005242 20 20 0,000 0,01751033 0,02598894 ! activation of JUN kinase activity GO:0007257 20 20 0,000 0,01751033 0,02597814 ! cyclic nucleotide binding GO:0030551 22 20 0,000 0,01751033 0,02596735 ! somatic diversification of immunoglobulins GO:0016445 20 20 0,000 0,01751033 0,02595657 ! microvillus GO:0005902 20 20 0,000 0,01751033 0,0259458 ! tumor necrosis factor receptor binding GO:0005164 20 20 0,000 0,01751033 0,02593504 ! ATP-dependent RNA helicase activity GO:0004004 20 20 0,000 0,01751033 0,02592429 ! positive regulation of protein catabolic process GO:0045732 22 21 0,000 0,01837837 0,02719816 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 22 21 0,000 0,01837837 0,02718689 ! growth cone GO:0030426 22 21 0,000 0,01837837 0,02717564 ! oligosaccharide metabolic process GO:0009311 23 21 0,000 0,01837837 0,02716439 ! regulation of anti-apoptosis GO:0045767 21 21 0,000 0,01837837 0,02715315 ! hormone secretion GO:0046879 22 21 0,000 0,01837837 0,02714192 ! protein amino acid O-linked glycosylation GO:0006493 22 21 0,000 0,01837837 0,0271307 ! transition metal ion transmembrane transporter activity GO:0046915 21 21 0,000 0,01837837 0,02711949 ! voltage-gated calcium channel complex GO:0005891 24 21 0,000 0,01837837 0,02710829 GO:0034704|calcium channel complex, ! dicarboxylic acid metabolic process GO:0043648 22 21 0,000 0,01837837 0,02709709 ! apoptotic mitochondrial changes GO:0008637 21 21 0,000 0,01837837 0,02708591 ! protein phosphatase type 2A regulator activity GO:0008601 23 21 0,000 0,01837837 0,02707474 ! histone-lysine N-methyltransferase activity GO:0018024 23 21 0,000 0,01837837 0,02706357 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! activation of pro-apoptotic gene products GO:0008633 22 21 0,000 0,01837837 0,02705242 ! mitochondrial membrane organization GO:0007006 22 21 0,000 0,01837837 0,02704127 ! central nervous system neuron differentiation GO:0021953 22 21 0,000 0,01837837 0,02703013 ! Golgi stack GO:0005795 25 21 0,000 0,01837837 0,027019 ! regulation of endothelial cell migration GO:0010594 21 21 0,000 0,01837837 0,02700788 ! muscle cell development GO:0055001 21 21 0,000 0,01837837 0,02699677 ! cholesterol biosynthetic process GO:0006695 22 21 0,000 0,01837837 0,02698567 ! regulation of vasoconstriction GO:0019229 22 21 0,000 0,01837837 0,02697458 ! deacetylase activity GO:0019213 22 21 0,000 0,01837837 0,0269635 ! phosphatase inhibitor activity GO:0019212 23 21 0,000 0,01837837 0,02695243 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,01837837 0,02694136 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! sensory perception of pain GO:0019233 21 21 0,000 0,01837837 0,02693031 ! pentose metabolic process GO:0019321 22 21 0,000 0,01837837 0,02691926 ! collagen fibril organization GO:0030199 22 21 0,000 0,01837837 0,02690822 ! platelet activation GO:0030168 23 21 0,000 0,01837837 0,0268972 ! response to glucocorticoid stimulus GO:0051384 22 21 0,000 0,01837837 0,02688618 ! trans-Golgi network transport vesicle GO:0030140 24 21 0,000 0,01837837 0,02687517 ! glutathione metabolic process GO:0006749 21 21 0,000 0,01837837 0,02686417 ! terpenoid metabolic process GO:0006721 21 21 0,000 0,01837837 0,02685317 ! cyclase activity GO:0009975 21 21 0,000 0,01837837 0,02684219 ! negative regulation of cytokine production GO:0001818 21 21 0,000 0,01837837 0,02683122 ! fatty acid binding GO:0005504 21 21 0,000 0,01837837 0,02682025 ! gut development GO:0048565 21 21 0,000 0,01837837 0,0268093 ! acetyl-CoA catabolic process GO:0046356 21 21 0,000 0,01837837 0,02679835 GO:0006099|tricarboxylic acid cycle, ! phosphoinositide phospholipase C activity GO:0004435 21 21 0,000 0,01837837 0,02678741 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! protein tetramerization GO:0051262 22 21 0,000 0,01837837 0,02677648 ! regulation of microtubule polymerization or depolymerization GO:0031110 23 21 0,000 0,01837837 0,02676556 ! sulfur amino acid metabolic process GO:0000096 22 21 0,000 0,01837837 0,02675465 ! voltage-gated anion channel activity GO:0008308 21 21 0,000 0,01837837 0,02674375 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,01837837 0,02673286 ! cellular polysaccharide biosynthetic process GO:0033692 21 21 0,000 0,01837837 0,02672197 ! positive regulation of JAK-STAT cascade GO:0046427 22 21 0,000 0,01837837 0,02671109 ! sterol binding GO:0032934 21 21 0,000 0,01837837 0,02670023 ! regulation of chemotaxis GO:0050920 21 21 0,000 0,01837837 0,02668937 ! regulation of carbohydrate metabolic process GO:0006109 22 21 0,000 0,01837837 0,02667852 GO:0010675|regulation of cellular carbohydrate metabolic process, ! superoxide metabolic process GO:0006801 21 21 0,000 0,01837837 0,02666768 ! calcium-dependent cell-cell adhesion GO:0016339 21 21 0,000 0,01837837 0,02665685 ! phosphatase binding GO:0019902 22 21 0,000 0,01837837 0,02664602 ! NAD+ ADP-ribosyltransferase activity GO:0003950 21 21 0,000 0,01837837 0,02663521 ! positive regulation of cytoskeleton organization GO:0051495 21 21 0,000 0,01837837 0,02662441 ! negative regulation of DNA replication GO:0008156 25 21 0,000 0,01837837 0,02661361 ! vesicle targeting GO:0006903 22 21 0,000 0,01837837 0,02660282 ! vesicle docking during exocytosis GO:0006904 21 21 0,000 0,01837837 0,02659204 ! cell structure disassembly during apoptosis GO:0006921 21 21 0,000 0,01837837 0,02658127 ! RNA-dependent ATPase activity GO:0008186 21 21 0,000 0,01837837 0,02657051 ! renal system process GO:0003014 22 21 0,000 0,01837837 0,02655976 ! base-excision repair GO:0006284 21 21 0,000 0,01837837 0,02654901 ! positive regulation of leukocyte mediated immunity GO:0002705 25 21 0,000 0,01837837 0,02653828 GO:0002708|positive regulation of lymphocyte mediated immunity, ! nuclear-transcribed mRNA catabolic process GO:0000956 22 21 0,000 0,01837837 0,02652755 ! apoptotic protease activator activity GO:0016505 21 21 0,000 0,01837837 0,02651683 ! fatty acid transport GO:0015908 21 21 0,000 0,01837837 0,02650612 ! sarcoplasmic reticulum GO:0016529 22 21 0,000 0,01837837 0,02649542 ! positive regulation of tissue remodeling GO:0034105 22 21 0,000 0,01837837 0,02648473 ! collagen catabolic process GO:0030574 21 21 0,000 0,01837837 0,02647405 ! pyrimidine nucleotide biosynthetic process GO:0006221 25 21 0,000 0,01837837 0,02646337 ! regulation of multi-organism process GO:0043900 21 21 0,000 0,01837837 0,0264527 ! ubiquitin-specific protease activity GO:0004843 22 21 0,000 0,01837837 0,02644205 ! positive regulation of DNA replication GO:0045740 23 22 0,000 0,0192457 0,02767878 ! site of polarized growth GO:0030427 23 22 0,000 0,0192457 0,02766764 ! positive regulation of cell adhesion GO:0045785 23 22 0,000 0,0192457 0,0276565 ! leukocyte adhesion GO:0007159 27 22 0,000 0,0192457 0,02764538 ! glutamate signaling pathway GO:0007215 25 22 0,000 0,0192457 0,02763426 ! potassium channel regulator activity GO:0015459 24 22 0,000 0,0192457 0,02762315 ! peroxisome organization GO:0007031 22 22 0,000 0,0192457 0,02761206 ! cellular response to reactive oxygen species GO:0034614 22 22 0,000 0,0192457 0,02760097 ! polysaccharide catabolic process GO:0000272 22 22 0,000 0,0192457 0,02758989 ! response to starvation GO:0042594 23 22 0,000 0,0192457 0,02757882 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 22 22 0,000 0,0192457 0,02756775 ! coenzyme catabolic process GO:0009109 22 22 0,000 0,0192457 0,0275567 ! regulation of insulin secretion GO:0050796 23 22 0,000 0,0192457 0,02754565 ! membrane depolarization GO:0051899 24 22 0,000 0,0192457 0,02753462 ! somitogenesis GO:0001756 23 22 0,000 0,0192457 0,02752359 ! regulation of cytokine secretion GO:0050707 22 22 0,000 0,0192457 0,02751257 ! natural killer cell activation GO:0030101 22 22 0,000 0,0192457 0,02750156 ! aromatic amino acid family metabolic process GO:0009072 25 22 0,000 0,0192457 0,02749056 ! basal plasma membrane GO:0009925 22 22 0,000 0,0192457 0,02747957 GO:0045178|basal part of cell, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 22 22 0,000 0,0192457 0,02746859 ! camera-type eye morphogenesis GO:0048593 25 22 0,000 0,0192457 0,02745761 ! telomere organization GO:0032200 23 22 0,000 0,0192457 0,02744665 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 24 22 0,000 0,0192457 0,02743569 GO:0060606|tube closure, ! response to molecule of bacterial origin GO:0002237 22 22 0,000 0,0192457 0,02742474 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 22 0,000 0,0192457 0,0274138 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 22 22 0,000 0,0192457 0,02740287 GO:0016444|somatic cell DNA recombination, ! cortical actin cytoskeleton GO:0030864 22 22 0,000 0,0192457 0,02739195 ! initiation of viral infection GO:0019059 22 22 0,000 0,0192457 0,02738104 ! regulation of neurotransmitter transport GO:0051588 23 22 0,000 0,0192457 0,02737013 ! macromolecular complex disassembly GO:0032984 23 22 0,000 0,0192457 0,02735924 ! response to ethanol GO:0045471 25 22 0,000 0,0192457 0,02734835 ! syntaxin binding GO:0019905 23 22 0,000 0,0192457 0,02733747 ! regulation of nitric oxide biosynthetic process GO:0045428 22 22 0,000 0,0192457 0,0273266 ! digestive system process GO:0022600 24 22 0,000 0,0192457 0,02731574 ! neurotransmitter transporter activity GO:0005326 22 22 0,000 0,0192457 0,02730489 ! autophagy GO:0006914 24 22 0,000 0,0192457 0,02729405 ! carbohydrate kinase activity GO:0019200 22 22 0,000 0,0192457 0,02728321 ! neuropeptide hormone activity GO:0005184 23 22 0,000 0,0192457 0,02727238 ! transaminase activity GO:0008483 23 22 0,000 0,0192457 0,02726157 ! sarcoplasm GO:0016528 23 22 0,000 0,0192457 0,02725076 ! metallocarboxypeptidase activity GO:0004181 23 22 0,000 0,0192457 0,02723996 ! cellular response to nutrient levels GO:0031669 23 22 0,000 0,0192457 0,02722916 ! positive regulation of nuclear division GO:0051785 22 22 0,000 0,0192457 0,02721838 GO:0045840|positive regulation of mitosis, ! nerve-nerve synaptic transmission GO:0007270 25 22 0,000 0,0192457 0,0272076 ! small conjugating protein-specific protease activity GO:0019783 24 22 0,000 0,0192457 0,02719684 ! pyrimidine nucleoside metabolic process GO:0006213 25 22 0,000 0,0192457 0,02718608 ! solute:cation antiporter activity GO:0015298 22 22 0,000 0,0192457 0,02717533 ! translational initiation GO:0006413 23 23 0,000 0,02011233 0,0283878 ! NF-kappaB binding GO:0051059 23 23 0,000 0,02011233 0,02837658 ! vesicle docking GO:0048278 23 23 0,000 0,02011233 0,02836538 ! muscle myosin complex GO:0005859 25 23 0,000 0,02011233 0,02835418 ! vasculogenesis GO:0001570 25 23 0,000 0,02011233 0,02834299 ! regulation of innate immune response GO:0045088 23 23 0,000 0,02011233 0,02833181 ! positive regulation of epithelial cell proliferation GO:0050679 24 23 0,000 0,02011233 0,02832064 ! sperm motility GO:0030317 23 23 0,000 0,02011233 0,02830947 ! response to corticosteroid stimulus GO:0031960 24 23 0,000 0,02011233 0,02829832 ! barbed-end actin filament capping GO:0051016 23 23 0,000 0,02011233 0,02828717 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 24 23 0,000 0,02011233 0,02827604 ! regulation of behavior GO:0050795 23 23 0,000 0,02011233 0,02826491 ! cardiac muscle tissue morphogenesis GO:0055008 24 23 0,000 0,02011233 0,02825379 GO:0060415|muscle tissue morphogenesis, ! cyclic nucleotide biosynthetic process GO:0009190 23 23 0,000 0,02011233 0,02824268 ! leukotriene metabolic process GO:0006691 23 23 0,000 0,02011233 0,02823158 ! positive regulation of T cell differentiation GO:0045582 27 23 0,000 0,02011233 0,02822048 ! glycolipid metabolic process GO:0006664 23 23 0,000 0,02011233 0,0282094 ! regulation of ARF GTPase activity GO:0032312 26 23 0,000 0,02011233 0,02819832 ! pallium development GO:0021543 23 23 0,000 0,02011233 0,02818726 ! GABA receptor activity GO:0016917 24 23 0,000 0,02011233 0,0281762 ! positive regulation of MAPKKK cascade GO:0043410 30 23 0,000 0,02011233 0,02816515 ! regulation of response to biotic stimulus GO:0002831 23 23 0,000 0,02011233 0,02815411 ! MHC class II receptor activity GO:0032395 23 23 0,000 0,02011233 0,02814308 ! nicotinamide metabolic process GO:0006769 23 23 0,000 0,02011233 0,02813205 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of neuron differentiation GO:0045665 23 23 0,000 0,02011233 0,02812104 ! aspartate family amino acid metabolic process GO:0009066 24 23 0,000 0,02011233 0,02811003 ! cell surface binding GO:0043498 25 23 0,000 0,02011233 0,02809903 ! collagen binding GO:0005518 27 23 0,000 0,02011233 0,02808804 ! insulin-like growth factor binding GO:0005520 23 23 0,000 0,02011233 0,02807706 ! regulation of amine transport GO:0051952 23 23 0,000 0,02011233 0,02806609 ! tissue homeostasis GO:0001894 24 23 0,000 0,02011233 0,02805513 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 25 23 0,000 0,02011233 0,02804417 ! protein import into nucleus, translocation GO:0000060 25 23 0,000 0,02011233 0,02803323 ! gluconeogenesis GO:0006094 24 23 0,000 0,02011233 0,02802229 ! iron ion transport GO:0006826 24 23 0,000 0,02011233 0,02801136 ! N-acetylglucosamine metabolic process GO:0006044 23 23 0,000 0,02011233 0,02800044 ! molting cycle process GO:0022404 23 23 0,000 0,02011233 0,02798953 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! circadian rhythm GO:0007623 24 23 0,000 0,02011233 0,02797863 ! tube lumen formation GO:0035148 26 23 0,000 0,02011233 0,02796773 ! insulin receptor signaling pathway GO:0008286 28 23 0,000 0,02011233 0,02795684 ! multicellular organismal response to stress GO:0033555 23 23 0,000 0,02011233 0,02794597 ! immune response-activating signal transduction GO:0002757 29 23 0,000 0,02011233 0,0279351 ! lymphocyte proliferation GO:0046651 29 23 0,000 0,02011233 0,02792423 ! fibroblast growth factor receptor signaling pathway GO:0008543 24 23 0,000 0,02011233 0,02791338 ! regulation of bone mineralization GO:0030500 25 23 0,000 0,02011233 0,02790254 ! single-stranded RNA binding GO:0003727 24 23 0,000 0,02011233 0,0278917 ! brush border GO:0005903 25 23 0,000 0,02011233 0,02788087 ! caveola GO:0005901 24 23 0,000 0,02011233 0,02787005 ! gap junction GO:0005921 23 23 0,000 0,02011233 0,02785924 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 25 24 0,000 0,02097825 0,02904743 ! regulation of transmembrane transport GO:0034762 24 24 0,000 0,02097825 0,02903617 ! heterotrimeric G-protein complex GO:0005834 24 24 0,000 0,02097825 0,02902492 ! protein amino acid acylation GO:0043543 26 24 0,000 0,02097825 0,02901368 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 24 0,000 0,02097825 0,02900245 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 25 24 0,000 0,02097825 0,02899123 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02097825 0,02898001 ! MHC class I protein complex GO:0042612 24 24 0,000 0,02097825 0,0289688 ! G-protein chemoattractant receptor activity GO:0001637 24 24 0,000 0,02097825 0,02895761 GO:0004950|chemokine receptor activity, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 24 24 0,000 0,02097825 0,02894642 ! early endosome membrane GO:0031901 26 24 0,000 0,02097825 0,02893524 ! primary neural tube formation GO:0014020 26 24 0,000 0,02097825 0,02892407 ! ARF GTPase activator activity GO:0008060 27 24 0,000 0,02097825 0,0289129 ! hydrogen peroxide metabolic process GO:0042743 24 24 0,000 0,02097825 0,02890175 ! immunoglobulin production GO:0002377 28 24 0,000 0,02097825 0,0288906 GO:0002440|production of molecular mediator of immune response, ! lipid kinase activity GO:0001727 26 24 0,000 0,02097825 0,02887946 ! positive regulation of protein secretion GO:0050714 26 24 0,000 0,02097825 0,02886833 ! MHC class I receptor activity GO:0032393 24 24 0,000 0,02097825 0,02885721 ! RNA splicing factor activity, transesterification mechanism GO:0031202 24 24 0,000 0,02097825 0,0288461 ! fat-soluble vitamin metabolic process GO:0006775 24 24 0,000 0,02097825 0,028835 ! regulation of osteoblast differentiation GO:0045667 27 24 0,000 0,02097825 0,0288239 ! cellular alkene metabolic process GO:0043449 24 24 0,000 0,02097825 0,02881282 ! somatic diversification of immune receptors GO:0002200 24 24 0,000 0,02097825 0,02880174 ! calcium-dependent phospholipid binding GO:0005544 24 24 0,000 0,02097825 0,02879067 ! positive regulation of JUN kinase activity GO:0043507 24 24 0,000 0,02097825 0,02877961 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 26 24 0,000 0,02097825 0,02876856 ! Z disc GO:0030018 27 24 0,000 0,02097825 0,02875752 ! negative regulation of lymphocyte activation GO:0051250 24 24 0,000 0,02097825 0,02874648 ! alkaloid metabolic process GO:0009820 24 24 0,000 0,02097825 0,02873545 ! neuron fate commitment GO:0048663 24 24 0,000 0,02097825 0,02872444 ! DNA catabolic process, endonucleolytic GO:0000737 24 24 0,000 0,02097825 0,02871343 ! glucosamine metabolic process GO:0006041 24 24 0,000 0,02097825 0,02870242 ! regulation of transcription factor import into nucleus GO:0042990 25 24 0,000 0,02097825 0,02869143 ! glucose transport GO:0015758 24 24 0,000 0,02097825 0,02868045 ! dendrite development GO:0016358 26 24 0,000 0,02097825 0,02866947 ! negative regulation of protein modification process GO:0031400 28 24 0,000 0,02097825 0,0286585 ! catechol metabolic process GO:0009712 27 24 0,000 0,02097825 0,02864754 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phospholipase A2 activity GO:0004623 26 24 0,000 0,02097825 0,02863659 ! immune response-regulating signal transduction GO:0002764 30 24 0,000 0,02097825 0,02862565 ! regulation of production of molecular mediator of immune response GO:0002700 28 24 0,000 0,02097825 0,02861472 ! DNA-directed DNA polymerase activity GO:0003887 25 24 0,000 0,02097825 0,02860379 ! synaptogenesis GO:0007416 25 24 0,000 0,02097825 0,02859287 ! selenium binding GO:0008430 24 24 0,000 0,02097825 0,02858196 ! leukocyte proliferation GO:0070661 30 24 0,000 0,02097825 0,02857106 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 26 24 0,000 0,02097825 0,02856017 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 25 25 0,000 0,02184346 0,02972675 ! RNA export from nucleus GO:0006405 27 25 0,000 0,02184346 0,02971543 ! phenol metabolic process GO:0018958 28 25 0,000 0,02184346 0,02970411 ! myelination GO:0042552 26 25 0,000 0,02184346 0,02969281 ! epidermal growth factor receptor signaling pathway GO:0007173 28 25 0,000 0,02184346 0,02968151 ! actin filament GO:0005884 28 25 0,000 0,02184346 0,02967022 ! hexose transport GO:0008645 25 25 0,000 0,02184346 0,02965894 GO:0015749|monosaccharide transport, ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 27 25 0,000 0,02184346 0,02964766 ! PML body GO:0016605 28 25 0,000 0,02184346 0,0296364 ! negative regulation of cell development GO:0010721 28 25 0,000 0,02184346 0,02962514 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 27 25 0,000 0,02184346 0,0296139 ! cell fate determination GO:0001709 25 25 0,000 0,02184346 0,02960266 ! regulation of oxidoreductase activity GO:0051341 25 25 0,000 0,02184346 0,02959143 ! group transfer coenzyme metabolic process GO:0006752 26 25 0,000 0,02184346 0,02958021 ! hormone transport GO:0009914 26 25 0,000 0,02184346 0,02956899 ! neuromuscular process controlling balance GO:0050885 26 25 0,000 0,02184346 0,02955779 ! porphyrin metabolic process GO:0006778 27 25 0,000 0,02184346 0,02954659 GO:0033013|tetrapyrrole metabolic process, ! blastocyst development GO:0001824 25 25 0,000 0,02184346 0,0295354 ! regulation of JUN kinase activity GO:0043506 25 25 0,000 0,02184346 0,02952423 ! cell adhesion molecule binding GO:0050839 27 25 0,000 0,02184346 0,02951305 ! negative regulation of actin filament depolymerization GO:0030835 25 25 0,000 0,02184346 0,02950189 ! acetyl-CoA metabolic process GO:0006084 25 25 0,000 0,02184346 0,02949074 ! membrane lipid catabolic process GO:0046466 26 25 0,000 0,02184346 0,02947959 ! zinc ion transport GO:0006829 26 25 0,000 0,02184346 0,02946846 ! heterochromatin GO:0000792 26 25 0,000 0,02184346 0,02945733 ! cellular iron ion homeostasis GO:0006879 25 25 0,000 0,02184346 0,02944621 ! phototransduction GO:0007602 25 25 0,000 0,02184346 0,0294351 ! keratinization GO:0031424 26 25 0,000 0,02184346 0,02942399 ! spinal cord development GO:0021510 25 25 0,000 0,02184346 0,0294129 ! cyclin-dependent protein kinase activity GO:0004693 26 25 0,000 0,02184346 0,02940181 ! regulation of smooth muscle contraction GO:0006940 28 25 0,000 0,02184346 0,02939073 ! response to toxin GO:0009636 25 25 0,000 0,02184346 0,02937966 ! regulation of peptide secretion GO:0002791 26 25 0,000 0,02184346 0,0293686 ! determination of left/right symmetry GO:0007368 25 25 0,000 0,02184346 0,02935755 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 25 0,000 0,02184346 0,0293465 ! regulation of interleukin-6 production GO:0032675 25 25 0,000 0,02184346 0,02933547 ! voltage-gated calcium channel activity GO:0005245 28 25 0,000 0,02184346 0,02932444 ! phospholipid transport GO:0015914 26 25 0,000 0,02184346 0,02931342 ! peptidase activator activity GO:0016504 25 25 0,000 0,02184346 0,02930241 ! protein localization in mitochondrion GO:0070585 26 25 0,000 0,02184346 0,0292914 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 25 25 0,000 0,02184346 0,02928041 ! ethanolamine and derivative metabolic process GO:0042439 28 25 0,000 0,02184346 0,02926942 ! small nuclear ribonucleoprotein complex GO:0030532 25 25 0,000 0,02184346 0,02925844 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 25 25 0,000 0,02184346 0,02924747 ! negative regulation of transcription regulator activity GO:0090048 26 25 0,000 0,02184346 0,02923651 GO:0043433|negative regulation of transcription factor activity, ! acetylgalactosaminyltransferase activity GO:0008376 27 25 0,000 0,02184346 0,02922555 ! solute:solute antiporter activity GO:0015300 26 26 0,000 0,02270797 0,03037085 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 27 26 0,000 0,02270797 0,03035948 ! regeneration GO:0031099 26 26 0,000 0,02270797 0,03034811 ! cholesterol homeostasis GO:0042632 26 26 0,000 0,02270797 0,03033676 GO:0055092|sterol homeostasis, ! peptidyl-tyrosine phosphorylation GO:0018108 27 26 0,000 0,02270797 0,03032541 ! ureteric bud development GO:0001657 26 26 0,000 0,02270797 0,03031408 ! neural crest cell development GO:0014032 26 26 0,000 0,02270797 0,03030275 GO:0014033|neural crest cell differentiation, ! negative regulation of protein kinase cascade GO:0010741 27 26 0,000 0,02270797 0,03029143 ! cellular response to oxidative stress GO:0034599 26 26 0,000 0,02270797 0,03028012 ! lipid oxidation GO:0034440 26 26 0,000 0,02270797 0,03026882 GO:0019395|fatty acid oxidation, ! positive regulation of lymphocyte differentiation GO:0045621 30 26 0,000 0,02270797 0,03025752 ! pyridine nucleotide metabolic process GO:0019362 26 26 0,000 0,02270797 0,03024624 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 26 26 0,000 0,02270797 0,03023496 ! carboxy-lyase activity GO:0016831 26 26 0,000 0,02270797 0,03022369 ! myeloid leukocyte activation GO:0002274 27 26 0,000 0,02270797 0,03021243 ! negative regulation of neuron apoptosis GO:0043524 26 26 0,000 0,02270797 0,03020118 ! negative regulation of catabolic process GO:0009895 28 26 0,000 0,02270797 0,03018993 ! lysine N-acetyltransferase activity GO:0004468 26 26 0,000 0,02270797 0,0301787 GO:0004402|histone acetyltransferase activity, ! regulation of actin filament depolymerization GO:0030834 26 26 0,000 0,02270797 0,03016747 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02270797 0,03015625 ! determination of bilateral symmetry GO:0009855 26 26 0,000 0,02270797 0,03014504 GO:0009799|determination of symmetry, ! regulation of cellular catabolic process GO:0031329 28 26 0,000 0,02270797 0,03013384 ! pyruvate metabolic process GO:0006090 27 26 0,000 0,02270797 0,03012264 ! cellular component assembly involved in morphogenesis GO:0010927 26 26 0,000 0,02270797 0,03011146 ! histone methyltransferase activity GO:0042054 29 26 0,000 0,02270797 0,03010028 ! regulation of endothelial cell proliferation GO:0001936 27 26 0,000 0,02270797 0,03008911 ! chemokine binding GO:0019956 26 26 0,000 0,02270797 0,03007795 ! receptor metabolic process GO:0043112 28 26 0,000 0,02270797 0,0300668 ! nucleotide kinase activity GO:0019201 30 26 0,000 0,02270797 0,03005566 ! histone deacetylase complex GO:0000118 27 26 0,000 0,02270797 0,03004452 ! phospholipase C activity GO:0004629 27 26 0,000 0,02270797 0,03003339 ! negative regulation of leukocyte activation GO:0002695 26 26 0,000 0,02270797 0,03002227 ! receptor regulator activity GO:0030545 26 26 0,000 0,02270797 0,03001116 ! galactosyltransferase activity GO:0008378 27 26 0,000 0,02270797 0,03000006 ! response to heat GO:0009408 26 26 0,000 0,02270797 0,02998896 ! positive regulation of immune effector process GO:0002699 30 26 0,000 0,02270797 0,02997788 ! mRNA catabolic process GO:0006402 28 27 0,000 0,02357177 0,03110672 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 28 27 0,000 0,02357177 0,03109523 ! actomyosin structure organization GO:0031032 28 27 0,000 0,02357177 0,03108375 ! nucleotide receptor activity, G-protein coupled GO:0001608 27 27 0,000 0,02357177 0,03107228 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 28 27 0,000 0,02357177 0,03106081 ! iron ion homeostasis GO:0055072 27 27 0,000 0,02357177 0,03104935 ! lipoprotein binding GO:0008034 29 27 0,000 0,02357177 0,0310379 ! deaminase activity GO:0019239 27 27 0,000 0,02357177 0,03102646 ! mesoderm formation GO:0001707 28 27 0,000 0,02357177 0,03101503 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 27 27 0,000 0,02357177 0,03100361 ! phospholipid transporter activity GO:0005548 29 27 0,000 0,02357177 0,03099219 ! neural tube formation GO:0001841 29 27 0,000 0,02357177 0,03098079 ! mitotic sister chromatid segregation GO:0000070 27 27 0,000 0,02357177 0,03096939 ! regulation of smooth muscle cell proliferation GO:0048660 27 27 0,000 0,02357177 0,030958 ! integrin complex GO:0008305 28 27 0,000 0,02357177 0,03094662 ! nuclear chromatin GO:0000790 28 27 0,000 0,02357177 0,03093524 ! collagen metabolic process GO:0032963 27 27 0,000 0,02357177 0,03092388 ! post-embryonic development GO:0009791 29 27 0,000 0,02357177 0,03091252 ! antigen processing and presentation of peptide antigen GO:0048002 28 27 0,000 0,02357177 0,03090117 ! ovulation cycle process GO:0022602 27 27 0,000 0,02357177 0,03088983 ! SNARE binding GO:0000149 28 27 0,000 0,02357177 0,0308785 ! biogenic amine biosynthetic process GO:0042401 28 27 0,000 0,02357177 0,03086718 ! spindle pole GO:0000922 28 27 0,000 0,02357177 0,03085586 ! anion:cation symporter activity GO:0015296 28 27 0,000 0,02357177 0,03084456 ! trans-Golgi network GO:0005802 29 28 0,000 0,02443487 0,03196224 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 28 0,000 0,02443487 0,03195054 ! cholesterol transport GO:0030301 28 28 0,000 0,02443487 0,03193884 GO:0015918|sterol transport, ! thyroid hormone receptor binding GO:0046966 29 28 0,000 0,02443487 0,03192715 ! dynein complex GO:0030286 29 28 0,000 0,02443487 0,03191548 ! formation of primary germ layer GO:0001704 29 28 0,000 0,02443487 0,03190381 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 30 28 0,000 0,02443487 0,03189215 ! ovulation cycle GO:0042698 28 28 0,000 0,02443487 0,03188049 ! peptidyl-tyrosine modification GO:0018212 29 28 0,000 0,02443487 0,03186885 ! cofactor catabolic process GO:0051187 30 28 0,000 0,02443487 0,03185722 ! DNA damage checkpoint GO:0000077 31 28 0,000 0,02443487 0,03184559 ! negative regulation of actin filament polymerization GO:0030837 28 28 0,000 0,02443487 0,03183397 ! cortical cytoskeleton GO:0030863 29 28 0,000 0,02443487 0,03182236 ! icosanoid biosynthetic process GO:0046456 29 28 0,000 0,02443487 0,03181076 ! amino sugar metabolic process GO:0006040 28 28 0,000 0,02443487 0,03179917 ! membrane docking GO:0022406 28 28 0,000 0,02443487 0,03178758 ! sister chromatid segregation GO:0000819 28 28 0,000 0,02443487 0,03177601 ! detection of light stimulus involved in sensory perception GO:0050962 28 28 0,000 0,02443487 0,03176444 GO:0050908|detection of light stimulus involved in visual perception, ! cell junction assembly GO:0034329 30 28 0,000 0,02443487 0,03175288 ! complement activation, classical pathway GO:0006958 31 28 0,000 0,02443487 0,03174133 ! multicellular organismal catabolic process GO:0044243 28 28 0,000 0,02443487 0,03172979 ! response to mechanical stimulus GO:0009612 28 28 0,000 0,02443487 0,03171825 ! caspase regulator activity GO:0043028 28 28 0,000 0,02443487 0,03170673 ! ensheathment of neurons GO:0007272 29 28 0,000 0,02443487 0,03169521 GO:0008366|axon ensheathment, ! DNA polymerase activity GO:0034061 29 28 0,000 0,02443487 0,0316837 ! calcium-mediated signaling GO:0019722 28 28 0,000 0,02443487 0,0316722 ! neurotransmitter secretion GO:0007269 29 28 0,000 0,02443487 0,03166071 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 28 28 0,000 0,02443487 0,03164923 ! glycogen metabolic process GO:0005977 29 28 0,000 0,02443487 0,03163775 ! RNA helicase activity GO:0003724 28 28 0,000 0,02443487 0,03162628 ! Rho GTPase activator activity GO:0005100 32 28 0,000 0,02443487 0,03161482 ! symbiosis, encompassing mutualism through parasitism GO:0044403 32 28 0,000 0,02443487 0,03160337 ! transferase activity, transferring nitrogenous groups GO:0016769 30 29 0,000 0,02529726 0,03270692 ! spliceosomal snRNP biogenesis GO:0000387 30 29 0,000 0,02529726 0,03269508 ! odontogenesis of dentine-containing tooth GO:0042475 30 29 0,000 0,02529726 0,03268326 ! scavenger receptor activity GO:0005044 30 29 0,000 0,02529726 0,03267144 ! spindle organization GO:0007051 30 29 0,000 0,02529726 0,03265962 ! mesoderm morphogenesis GO:0048332 30 29 0,000 0,02529726 0,03264782 ! male gonad development GO:0008584 29 29 0,000 0,02529726 0,03263603 ! response to organic cyclic substance GO:0014070 31 29 0,000 0,02529726 0,03262424 ! negative regulation of MAP kinase activity GO:0043407 30 29 0,000 0,02529726 0,03261246 ! sterol biosynthetic process GO:0016126 30 29 0,000 0,02529726 0,03260069 ! endocytic vesicle GO:0030139 29 29 0,000 0,02529726 0,03258893 ! Rho GTPase binding GO:0017048 32 29 0,000 0,02529726 0,03257718 ! serine family amino acid metabolic process GO:0009069 30 29 0,000 0,02529726 0,03256544 ! fatty acid catabolic process GO:0009062 30 29 0,000 0,02529726 0,0325537 ! regulation of calcium ion transport GO:0051924 32 29 0,000 0,02529726 0,03254197 ! negative regulation of protein polymerization GO:0032272 29 29 0,000 0,02529726 0,03253026 ! glucan metabolic process GO:0044042 30 29 0,000 0,02529726 0,03251855 GO:0006073|cellular glucan metabolic process, ! regulation of synaptic plasticity GO:0048167 29 29 0,000 0,02529726 0,03250684 ! proteoglycan metabolic process GO:0006029 30 29 0,000 0,02529726 0,03249515 ! xenobiotic metabolic process GO:0006805 29 29 0,000 0,02529726 0,03248347 ! negative regulation of response to external stimulus GO:0032102 29 29 0,000 0,02529726 0,03247179 ! positive regulation of T cell proliferation GO:0042102 33 29 0,000 0,02529726 0,03246012 ! steroid dehydrogenase activity GO:0016229 29 29 0,000 0,02529726 0,03244846 ! regulation of protein import into nucleus GO:0042306 30 29 0,000 0,02529726 0,03243681 ! clathrin coated vesicle membrane GO:0030665 32 29 0,000 0,02529726 0,03242517 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 30 29 0,000 0,02529726 0,03241353 ! cytosolic small ribosomal subunit GO:0022627 29 29 0,000 0,02529726 0,03240191 ! detection of visible light GO:0009584 29 29 0,000 0,02529726 0,03239029 ! tumor necrosis factor receptor superfamily binding GO:0032813 29 29 0,000 0,02529726 0,03237868 ! acetylglucosaminyltransferase activity GO:0008375 30 29 0,000 0,02529726 0,03236708 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,02529726 0,03235549 ! gene silencing GO:0016458 29 29 0,000 0,02529726 0,0323439 ! hormone binding GO:0042562 30 30 0,000 0,02615895 0,03343365 ! negative regulation of DNA metabolic process GO:0051053 34 30 0,000 0,02615895 0,03342169 ! inner ear morphogenesis GO:0042472 31 30 0,000 0,02615895 0,03340973 ! GPI anchor biosynthetic process GO:0006506 32 30 0,000 0,02615895 0,03339779 ! acrosomal vesicle GO:0001669 32 30 0,000 0,02615895 0,03338585 ! negative regulation of DNA binding GO:0043392 31 30 0,000 0,02615895 0,03337392 ! triglyceride metabolic process GO:0006641 31 30 0,000 0,02615895 0,033362 ! erythrocyte differentiation GO:0030218 32 30 0,000 0,02615895 0,03335009 ! glutamate receptor activity GO:0008066 33 30 0,000 0,02615895 0,03333819 ! ceramide metabolic process GO:0006672 30 30 0,000 0,02615895 0,0333263 ! cell fate specification GO:0001708 31 30 0,000 0,02615895 0,03331441 ! hexose biosynthetic process GO:0019319 32 30 0,000 0,02615895 0,03330253 ! negative regulation of hydrolase activity GO:0051346 32 30 0,000 0,02615895 0,03329067 ! PDZ domain binding GO:0030165 32 30 0,000 0,02615895 0,03327881 ! AP-type membrane coat adaptor complex GO:0030119 31 30 0,000 0,02615895 0,03326695 GO:0030131|clathrin adaptor complex, ! embryonic epithelial tube formation GO:0001838 32 30 0,000 0,02615895 0,03325511 ! negative regulation of cell activation GO:0050866 31 30 0,000 0,02615895 0,03324328 ! negative regulation of protein transport GO:0051224 30 30 0,000 0,02615895 0,03323145 ! negative regulation of protein complex assembly GO:0031333 30 30 0,000 0,02615895 0,03321963 ! regulation of JAK-STAT cascade GO:0046425 32 30 0,000 0,02615895 0,03320782 ! multicellular organismal macromolecule metabolic process GO:0044259 30 30 0,000 0,02615895 0,03319602 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 33 30 0,000 0,02615895 0,03318423 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,02615895 0,03317245 ! regulation of systemic arterial blood pressure GO:0003073 32 30 0,000 0,02615895 0,03316067 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 31 30 0,000 0,02615895 0,0331489 ! aminopeptidase activity GO:0004177 32 30 0,000 0,02615895 0,03313714 ! detection of light stimulus GO:0009583 30 30 0,000 0,02615895 0,03312539 ! L-amino acid transmembrane transporter activity GO:0015179 30 30 0,000 0,02615895 0,03311365 ! cysteine-type endopeptidase inhibitor activity GO:0004869 32 30 0,000 0,02615895 0,03310192 ! meiosis I GO:0007127 31 31 0,000 0,02701994 0,03417931 ! negative regulation of cell adhesion GO:0007162 33 31 0,000 0,02701994 0,03416721 ! striated muscle cell differentiation GO:0051146 31 31 0,000 0,02701994 0,03415511 ! GPI anchor metabolic process GO:0006505 33 31 0,000 0,02701994 0,03414303 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,02701994 0,03413095 ! spliceosome assembly GO:0000245 32 31 0,000 0,02701994 0,03411888 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 32 31 0,000 0,02701994 0,03410682 GO:0004601|peroxidase activity, ! unsaturated fatty acid biosynthetic process GO:0006636 32 31 0,000 0,02701994 0,03409477 ! NAD or NADH binding GO:0051287 31 31 0,000 0,02701994 0,03408272 ! positive regulation of neurogenesis GO:0050769 32 31 0,000 0,02701994 0,03407069 ! cyclic nucleotide metabolic process GO:0009187 31 31 0,000 0,02701994 0,03405866 ! nucleotide catabolic process GO:0009166 32 31 0,000 0,02701994 0,03404664 ! replication fork GO:0005657 32 31 0,000 0,02701994 0,03403463 ! placenta development GO:0001890 31 31 0,000 0,02701994 0,03402263 ! condensed nuclear chromosome GO:0000794 32 31 0,000 0,02701994 0,03401064 ! regulation of pH GO:0006885 31 31 0,000 0,02701994 0,03399866 ! protein methyltransferase activity GO:0008276 36 31 0,000 0,02701994 0,03398668 ! acute-phase response GO:0006953 32 31 0,000 0,02701994 0,03397471 ! peptide transport GO:0015833 32 31 0,000 0,02701994 0,03396276 ! respiratory gaseous exchange GO:0007585 32 31 0,000 0,02701994 0,03395081 ! DNA integrity checkpoint GO:0031570 34 31 0,000 0,02701994 0,03393886 ! Golgi-associated vesicle membrane GO:0030660 34 31 0,000 0,02701994 0,03392693 ! regulation of protein stability GO:0031647 32 31 0,000 0,02701994 0,03391501 ! sarcolemma GO:0042383 33 31 0,000 0,02701994 0,03390309 ! vesicle localization GO:0051648 32 31 0,000 0,02701994 0,03389118 ! response to hydrogen peroxide GO:0042542 34 32 0,000 0,02788022 0,03495796 ! DNA helicase activity GO:0003678 34 32 0,000 0,02788022 0,03494569 ! NADP or NADPH binding GO:0050661 33 32 0,000 0,02788022 0,03493342 ! pigment biosynthetic process GO:0046148 34 32 0,000 0,02788022 0,03492117 ! purinergic nucleotide receptor activity GO:0001614 34 32 0,000 0,02788022 0,03490893 GO:0016502|nucleotide receptor activity, ! female gonad development GO:0008585 32 32 0,000 0,02788022 0,03489669 ! late endosome membrane GO:0031902 32 32 0,000 0,02788022 0,03488446 ! positive regulation of cell development GO:0010720 33 32 0,000 0,02788022 0,03487225 ! hindbrain development GO:0030902 35 32 0,000 0,02788022 0,03486004 ! aerobic respiration GO:0009060 32 32 0,000 0,02788022 0,03484783 ! positive regulation of catabolic process GO:0009896 34 32 0,000 0,02788022 0,03483564 ! regulation of muscle development GO:0048634 33 32 0,000 0,02788022 0,03482346 GO:0016202|regulation of striated muscle tissue development, ! cation:sugar symporter activity GO:0005402 32 32 0,000 0,02788022 0,03481128 GO:0005351|sugar:hydrogen symporter activity, ! sphingoid metabolic process GO:0046519 32 32 0,000 0,02788022 0,03479911 ! response to ionizing radiation GO:0010212 33 32 0,000 0,02788022 0,03478695 ! flagellum GO:0019861 32 32 0,000 0,02788022 0,0347748 ! regulation of lymphocyte mediated immunity GO:0002706 36 32 0,000 0,02788022 0,03476266 ! I band GO:0031674 35 32 0,000 0,02788022 0,03475053 ! JAK-STAT cascade GO:0007259 34 32 0,000 0,02788022 0,0347384 ! double-stranded RNA binding GO:0003725 33 32 0,000 0,02788022 0,03472629 ! cellular response to insulin stimulus GO:0032869 37 32 0,000 0,02788022 0,03471418 ! adult locomotory behavior GO:0008344 33 32 0,000 0,02788022 0,03470208 ! pyrimidine nucleotide metabolic process GO:0006220 37 32 0,000 0,02788022 0,03468999 ! positive regulation of transcription factor activity GO:0051091 34 33 0,000 0,0287398 0,03574706 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 34 33 0,000 0,0287398 0,03573462 ! establishment or maintenance of cell polarity GO:0007163 33 33 0,000 0,0287398 0,03572218 ! platelet alpha granule lumen GO:0031093 34 33 0,000 0,0287398 0,03570975 ! negative regulation of binding GO:0051100 34 33 0,000 0,0287398 0,03569733 ! organelle envelope lumen GO:0031970 34 33 0,000 0,0287398 0,03568492 ! protein targeting to membrane GO:0006612 35 33 0,000 0,0287398 0,03567251 ! vesicle coat GO:0030120 36 33 0,000 0,0287398 0,03566012 ! endoribonuclease activity GO:0004521 34 33 0,000 0,0287398 0,03564773 ! eye morphogenesis GO:0048592 38 33 0,000 0,0287398 0,03563536 ! embryonic organ development GO:0048568 36 33 0,000 0,0287398 0,03562299 ! monosaccharide biosynthetic process GO:0046364 35 33 0,000 0,0287398 0,03561063 ! glial cell differentiation GO:0010001 33 33 0,000 0,0287398 0,03559827 ! cell junction organization GO:0034330 35 33 0,000 0,0287398 0,03558593 ! tissue remodeling GO:0048771 35 33 0,000 0,0287398 0,0355736 ! segmentation GO:0035282 34 33 0,000 0,0287398 0,03556127 ! positive regulation of gene-specific transcription GO:0043193 34 33 0,000 0,0287398 0,03554895 ! energy coupled proton transport, down electrochemical gradient GO:0015985 33 33 0,000 0,0287398 0,03553664 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 35 33 0,000 0,0287398 0,03552434 ! hormone biosynthetic process GO:0042446 33 33 0,000 0,0287398 0,03551205 ! O-acyltransferase activity GO:0008374 33 33 0,000 0,0287398 0,03549977 ! response to xenobiotic stimulus GO:0009410 33 33 0,000 0,0287398 0,03548749 ! cellular amide metabolic process GO:0043603 34 34 0,000 0,02959868 0,03653539 ! sugar transmembrane transporter activity GO:0051119 34 34 0,000 0,02959868 0,03652276 GO:0015144|carbohydrate transmembrane transporter activity, ! neural tube development GO:0021915 36 34 0,000 0,02959868 0,03651015 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 34 0,000 0,02959868 0,03649754 ! neutral lipid metabolic process GO:0006638 35 34 0,000 0,02959868 0,03648494 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 34 34 0,000 0,02959868 0,03647235 ! telencephalon development GO:0021537 34 34 0,000 0,02959868 0,03645977 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 35 34 0,000 0,02959868 0,0364472 ! integral to Golgi membrane GO:0030173 34 34 0,000 0,02959868 0,03643464 ! intramolecular oxidoreductase activity GO:0016860 35 34 0,000 0,02959868 0,03642208 ! collagen GO:0005581 35 34 0,000 0,02959868 0,03640954 ! development of primary female sexual characteristics GO:0046545 34 34 0,000 0,02959868 0,036397 GO:0046660|female sex differentiation, ! leukocyte chemotaxis GO:0030595 35 34 0,000 0,02959868 0,03638447 GO:0060326|cell chemotaxis, ! sodium channel activity GO:0005272 36 34 0,000 0,02959868 0,03637195 ! carboxypeptidase activity GO:0004180 35 34 0,000 0,02959868 0,03635944 ! spermatid development GO:0007286 34 34 0,000 0,02959868 0,03634693 ! BMP signaling pathway GO:0030509 35 34 0,000 0,02959868 0,03633444 ! specific RNA polymerase II transcription factor activity GO:0003704 35 34 0,000 0,02959868 0,03632195 ! mitotic cell cycle checkpoint GO:0007093 35 35 0,000 0,03045686 0,03736222 ! regulation of intracellular protein transport GO:0033157 37 35 0,000 0,03045686 0,03734939 ! vesicle lumen GO:0031983 37 35 0,000 0,03045686 0,03733657 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! metanephros development GO:0001656 35 35 0,000 0,03045686 0,03732376 ! regulation of action potential in neuron GO:0019228 38 35 0,000 0,03045686 0,03731096 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 39 35 0,000 0,03045686 0,03729816 ! cytokine production GO:0001816 35 35 0,000 0,03045686 0,03728537 ! carbon-carbon lyase activity GO:0016830 35 35 0,000 0,03045686 0,0372726 ! embryonic pattern specification GO:0009880 36 35 0,000 0,03045686 0,03725983 ! regulation of metal ion transport GO:0010959 38 35 0,000 0,03045686 0,03724707 ! energy reserve metabolic process GO:0006112 36 35 0,000 0,03045686 0,03723432 ! metalloexopeptidase activity GO:0008235 36 35 0,000 0,03045686 0,03722157 ! protein serine/threonine phosphatase complex GO:0008287 38 35 0,000 0,03045686 0,03720884 ! phagocytosis GO:0006909 37 35 0,000 0,03045686 0,03719611 ! regulation of ARF protein signal transduction GO:0032012 40 35 0,000 0,03045686 0,0371834 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 37 35 0,000 0,03045686 0,03717069 ! ion transmembrane transport GO:0034220 35 35 0,000 0,03045686 0,03715799 ! neuropeptide receptor activity GO:0008188 35 35 0,000 0,03045686 0,0371453 ! oxygen binding GO:0019825 36 35 0,000 0,03045686 0,03713262 ! regulation of leukocyte mediated immunity GO:0002703 39 35 0,000 0,03045686 0,03711994 ! erythrocyte homeostasis GO:0034101 37 35 0,000 0,03045686 0,03710728 ! peripheral nervous system development GO:0007422 37 35 0,000 0,03045686 0,03709462 ! female gamete generation GO:0007292 38 35 0,000 0,03045686 0,03708198 ! polyol metabolic process GO:0019751 36 35 0,000 0,03045686 0,03706934 ! negative regulation of adenylate cyclase activity GO:0007194 38 36 0,000 0,03131433 0,0381 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of hormone secretion GO:0046883 38 36 0,000 0,03131433 0,03808702 ! monocarboxylic acid binding GO:0033293 37 36 0,000 0,03131433 0,03807405 ! polysaccharide biosynthetic process GO:0000271 36 36 0,000 0,03131433 0,03806109 ! regulation of axonogenesis GO:0050770 39 36 0,000 0,03131433 0,03804814 ! glycerol ether metabolic process GO:0006662 37 36 0,000 0,03131433 0,0380352 ! regulation of proteolysis GO:0030162 37 36 0,000 0,03131433 0,03802227 ! integral to endoplasmic reticulum membrane GO:0030176 36 36 0,000 0,03131433 0,03800934 ! regulation of adaptive immune response GO:0002819 40 36 0,000 0,03131433 0,03799643 ! oxidoreduction coenzyme metabolic process GO:0006733 37 36 0,000 0,03131433 0,03798352 ! isoprenoid metabolic process GO:0006720 37 36 0,000 0,03131433 0,03797062 ! spermatid differentiation GO:0048515 36 36 0,000 0,03131433 0,03795773 ! phosphoinositide biosynthetic process GO:0046489 38 36 0,000 0,03131433 0,03794485 ! ER to Golgi vesicle-mediated transport GO:0006888 36 36 0,000 0,03131433 0,03793198 ! condensed chromosome kinetochore GO:0000777 37 36 0,000 0,03131433 0,03791912 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 38 36 0,000 0,03131433 0,03790627 ! neuropeptide binding GO:0042923 36 36 0,000 0,03131433 0,03789342 ! organic anion transport GO:0015711 37 36 0,000 0,03131433 0,03788058 ! carbohydrate homeostasis GO:0033500 38 36 0,000 0,03131433 0,03786776 GO:0042593|glucose homeostasis, ! complement activation GO:0006956 39 36 0,000 0,03131433 0,03785494 ! antigen binding GO:0003823 36 36 0,000 0,03131433 0,03784213 ! extrinsic to plasma membrane GO:0019897 36 36 0,000 0,03131433 0,03782933 ! cytokinesis GO:0000910 40 36 0,000 0,03131433 0,03781653 ! coated pit GO:0005905 42 36 0,000 0,03131433 0,03780375 ! protein amino acid N-linked glycosylation GO:0006487 40 37 0,000 0,03217111 0,03882495 ! ribonucleoside metabolic process GO:0009119 43 37 0,000 0,03217111 0,03881184 ! regulation of T cell differentiation GO:0045580 41 37 0,000 0,03217111 0,03879873 ! biopolymer methylation GO:0043414 42 37 0,000 0,03217111 0,03878563 ! intrinsic to Golgi membrane GO:0031228 37 37 0,000 0,03217111 0,03877254 ! protein homooligomerization GO:0051260 38 37 0,000 0,03217111 0,03875946 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 38 37 0,000 0,03217111 0,03874639 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 41 37 0,000 0,03217111 0,03873332 ! regulation of T cell proliferation GO:0042129 41 37 0,000 0,03217111 0,03872027 ! amino acid binding GO:0016597 40 37 0,000 0,03217111 0,03870722 ! maintenance of protein location GO:0045185 38 37 0,000 0,03217111 0,03869419 ! maintenance of location in cell GO:0051651 38 37 0,000 0,03217111 0,03868116 ! solute:hydrogen symporter activity GO:0015295 37 37 0,000 0,03217111 0,03866814 ! proton-transporting two-sector ATPase complex GO:0016469 37 37 0,000 0,03217111 0,03865513 ! ear morphogenesis GO:0042471 39 38 0,000 0,03302719 0,0396704 ! odontogenesis GO:0042476 40 38 0,000 0,03302719 0,03965706 ! organic ether metabolic process GO:0018904 39 38 0,000 0,03302719 0,03964373 ! alcohol biosynthetic process GO:0046165 40 38 0,000 0,03302719 0,03963041 ! monovalent inorganic cation homeostasis GO:0055067 39 38 0,000 0,03302719 0,0396171 ! positive regulation of DNA binding GO:0043388 39 38 0,000 0,03302719 0,03960379 ! B cell differentiation GO:0030183 40 38 0,000 0,03302719 0,0395905 ! clathrin coat GO:0030118 43 38 0,000 0,03302719 0,03957721 ! regulation of endocytosis GO:0030100 39 38 0,000 0,03302719 0,03956394 ! dorsal/ventral pattern formation GO:0009953 38 38 0,000 0,03302719 0,03955067 ! cell growth GO:0016049 40 38 0,000 0,03302719 0,03953741 ! positive regulation of defense response GO:0031349 38 38 0,000 0,03302719 0,03952416 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 38 0,000 0,03302719 0,03951092 ! condensed chromosome, centromeric region GO:0000779 39 38 0,000 0,03302719 0,03949769 ! learning GO:0007612 42 38 0,000 0,03302719 0,03948446 ! negative regulation of protein complex disassembly GO:0043242 40 38 0,000 0,03302719 0,03947125 ! monocarboxylic acid transport GO:0015718 39 38 0,000 0,03302719 0,03945804 ! endosome transport GO:0016197 40 38 0,000 0,03302719 0,03944485 ! hormone-mediated signaling GO:0009755 39 38 0,000 0,03302719 0,03943166 ! N-methyltransferase activity GO:0008170 42 38 0,000 0,03302719 0,03941848 ! cytosolic large ribosomal subunit GO:0022625 38 38 0,000 0,03302719 0,03940531 ! pigment metabolic process GO:0042440 42 38 0,000 0,03302719 0,03939215 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 38 38 0,000 0,03302719 0,039379 ! regulation of nucleocytoplasmic transport GO:0046822 41 39 0,000 0,03388257 0,0403854 ! Notch signaling pathway GO:0007219 41 39 0,000 0,03388257 0,04037192 ! induction of apoptosis by extracellular signals GO:0008624 39 39 0,000 0,03388257 0,04035846 ! keratin filament GO:0045095 41 39 0,000 0,03388257 0,040345 ! ER-Golgi intermediate compartment GO:0005793 42 39 0,000 0,03388257 0,04033155 ! peroxisomal membrane GO:0005778 40 39 0,000 0,03388257 0,04031811 GO:0031903|microbody membrane, ! mitochondrial respiratory chain complex I GO:0005747 39 39 0,000 0,03388257 0,04030468 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! actin filament binding GO:0051015 39 39 0,000 0,03388257 0,04029126 ! regulation of protein secretion GO:0050708 41 39 0,000 0,03388257 0,04027785 ! cis-trans isomerase activity GO:0016859 39 39 0,000 0,03388257 0,04026444 ! regulation of cell morphogenesis involved in differentiation GO:0010769 42 39 0,000 0,03388257 0,04025105 ! viral infectious cycle GO:0019058 39 39 0,000 0,03388257 0,04023766 ! mammary gland development GO:0030879 41 39 0,000 0,03388257 0,04022429 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 39 0,000 0,03388257 0,04021092 ! amine receptor activity GO:0008227 41 39 0,000 0,03388257 0,04019756 ! positive regulation of response to external stimulus GO:0032103 39 39 0,000 0,03388257 0,04018421 ! monosaccharide binding GO:0048029 39 39 0,000 0,03388257 0,04017087 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 39 39 0,000 0,03388257 0,04015753 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! phosphotransferase activity, phosphate group as acceptor GO:0016776 44 40 0,000 0,03473725 0,04115684 ! peptide metabolic process GO:0006518 41 40 0,000 0,03473725 0,04114319 ! regulation of Rab protein signal transduction GO:0032483 41 40 0,000 0,03473725 0,04112955 GO:0032313|regulation of Rab GTPase activity, ! T cell differentiation GO:0030217 45 40 0,000 0,03473725 0,04111591 ! regulation of multicellular organism growth GO:0040014 42 40 0,000 0,03473725 0,04110229 ! neuron migration GO:0001764 42 40 0,000 0,03473725 0,04108868 ! nuclear export GO:0051168 42 40 0,000 0,03473725 0,04107507 ! inositol or phosphatidylinositol kinase activity GO:0004428 42 40 0,000 0,03473725 0,04106147 ! structural constituent of muscle GO:0008307 43 40 0,000 0,03473725 0,04104789 ! gliogenesis GO:0042063 40 40 0,000 0,03473725 0,04103431 ! feeding behavior GO:0007631 40 40 0,000 0,03473725 0,04102074 ! positive regulation of cytokine biosynthetic process GO:0042108 41 40 0,000 0,03473725 0,04100718 ! sulfur compound biosynthetic process GO:0044272 41 40 0,000 0,03473725 0,04099363 ! inorganic anion transmembrane transporter activity GO:0015103 42 40 0,000 0,03473725 0,04098008 ! chromatin remodeling GO:0006338 43 40 0,000 0,03473725 0,04096655 ! response to insulin stimulus GO:0032868 45 40 0,000 0,03473725 0,04095303 ! activation of adenylate cyclase activity GO:0007190 42 41 0,000 0,03559123 0,04194597 ! positive regulation of binding GO:0051099 42 41 0,000 0,03559123 0,04193213 ! response to reactive oxygen species GO:0000302 43 41 0,000 0,03559123 0,0419183 ! solute:sodium symporter activity GO:0015370 41 41 0,000 0,03559123 0,04190448 ! regulation of translational initiation GO:0006446 41 41 0,000 0,03559123 0,04189067 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 44 41 0,000 0,03559123 0,04187686 GO:0046328|regulation of JNK cascade, ! mesenchymal cell development GO:0014031 43 41 0,000 0,03559123 0,04186307 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! heterocycle biosynthetic process GO:0018130 43 41 0,000 0,03559123 0,04184929 ! exonuclease activity GO:0004527 42 41 0,000 0,03559123 0,04183551 ! regulation of myeloid cell differentiation GO:0045637 43 41 0,000 0,03559123 0,04182175 ! positive regulation of cytokine production GO:0001819 42 41 0,000 0,03559123 0,04180799 ! positive regulation of protein transport GO:0051222 44 41 0,000 0,03559123 0,04179424 ! receptor-mediated endocytosis GO:0006898 43 41 0,000 0,03559123 0,0417805 ! regulation of neuron projection development GO:0010975 44 41 0,000 0,03559123 0,04176677 ! metal cluster binding GO:0051540 43 41 0,000 0,03559123 0,04175305 GO:0051536|iron-sulfur cluster binding, ! embryonic skeletal system morphogenesis GO:0048704 42 41 0,000 0,03559123 0,04173934 ! development of primary male sexual characteristics GO:0046546 41 41 0,000 0,03559123 0,04172563 ! Rab GTPase activator activity GO:0005097 42 41 0,000 0,03559123 0,04171194 ! RNA catabolic process GO:0006401 44 42 0,000 0,03644452 0,04269795 ! organellar ribosome GO:0000313 43 42 0,000 0,03644452 0,04268395 GO:0005761|mitochondrial ribosome, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 44 42 0,000 0,03644452 0,04266996 ! MHC protein complex GO:0042611 42 42 0,000 0,03644452 0,04265597 ! regulation of epithelial cell proliferation GO:0050678 44 42 0,000 0,03644452 0,04264199 ! negative regulation of cell migration GO:0030336 44 42 0,000 0,03644452 0,04262803 ! positive regulation of growth GO:0045927 42 42 0,000 0,03644452 0,04261407 ! icosanoid metabolic process GO:0006690 43 42 0,000 0,03644452 0,04260012 ! chemokine activity GO:0008009 42 42 0,000 0,03644452 0,04258618 ! ruffle GO:0001726 44 42 0,000 0,03644452 0,04257225 ! pigmentation GO:0043473 46 42 0,000 0,03644452 0,04255833 ! developmental growth GO:0048589 42 42 0,000 0,03644452 0,04254441 ! methylation GO:0032259 47 42 0,000 0,03644452 0,04253051 ! glycolysis GO:0006096 42 42 0,000 0,03644452 0,04251662 ! morphogenesis of embryonic epithelium GO:0016331 44 42 0,000 0,03644452 0,04250273 ! regulation of tube size GO:0035150 44 42 0,000 0,03644452 0,04248886 GO:0050880|regulation of blood vessel size, ! branching morphogenesis of a tube GO:0048754 43 42 0,000 0,03644452 0,04247499 ! general RNA polymerase II transcription factor activity GO:0016251 44 42 0,000 0,03644452 0,04246113 ! cellular amino acid derivative biosynthetic process GO:0042398 43 42 0,000 0,03644452 0,04244728 ! positive regulation of adenylate cyclase activity GO:0045762 44 43 0,000 0,0372971 0,04342613 ! transferase activity, transferring pentosyl groups GO:0016763 45 43 0,000 0,0372971 0,04341198 ! keratinocyte differentiation GO:0030216 46 43 0,000 0,0372971 0,04339783 ! epithelial cell differentiation GO:0030855 45 43 0,000 0,0372971 0,0433837 ! detection of stimulus involved in sensory perception GO:0050906 43 43 0,000 0,0372971 0,04336957 ! sulfotransferase activity GO:0008146 44 43 0,000 0,0372971 0,04335545 ! cellular polysaccharide metabolic process GO:0044264 44 43 0,000 0,0372971 0,04334135 ! channel regulator activity GO:0016247 46 43 0,000 0,0372971 0,04332725 ! histone modification GO:0016570 44 43 0,000 0,0372971 0,04331316 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 45 43 0,000 0,0372971 0,04329908 ! synaptosome GO:0019717 47 43 0,000 0,0372971 0,043285 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 45 44 0,000 0,03814899 0,04425928 ! platelet alpha granule GO:0031091 46 44 0,000 0,03814899 0,0442449 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 44 44 0,000 0,03814899 0,04423054 ! regulation of ossification GO:0030278 48 44 0,000 0,03814899 0,04421618 ! cell recognition GO:0008037 46 44 0,000 0,03814899 0,04420184 ! positive regulation of cyclase activity GO:0031281 45 44 0,000 0,03814899 0,0441875 ! regulation of lymphocyte differentiation GO:0045619 48 44 0,000 0,03814899 0,04417317 ! regulation of actin filament polymerization GO:0030833 45 44 0,000 0,03814899 0,04415885 ! cellular component disassembly GO:0022411 45 44 0,000 0,03814899 0,04414454 ! regulation of protein complex disassembly GO:0043244 46 44 0,000 0,03814899 0,04413024 ! regulation of ion transport GO:0043269 47 44 0,000 0,03814899 0,04411595 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 50 44 0,000 0,03814899 0,04410167 ! inner ear development GO:0048839 46 44 0,000 0,03814899 0,0440874 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 48 44 0,000 0,03814899 0,04407313 ! amino acid transmembrane transporter activity GO:0015171 44 44 0,000 0,03814899 0,04405888 ! negative regulation of immune system process GO:0002683 49 44 0,000 0,03814899 0,04404464 ! chemokine receptor binding GO:0042379 44 44 0,000 0,03814899 0,0440304 ! regulation of action potential GO:0001508 50 45 0,000 0,03900019 0,04499828 ! regulation of gene-specific transcription GO:0032583 47 45 0,000 0,03900019 0,04498375 ! cellular amino acid biosynthetic process GO:0008652 47 45 0,000 0,03900019 0,04496922 ! response to temperature stimulus GO:0009266 45 45 0,000 0,03900019 0,04495471 ! nucleoside monophosphate biosynthetic process GO:0009124 50 45 0,000 0,03900019 0,0449402 ! positive regulation of lyase activity GO:0051349 46 45 0,000 0,03900019 0,0449257 ! regulation of neuron apoptosis GO:0043523 45 45 0,000 0,03900019 0,04491122 ! excretion GO:0007588 46 45 0,000 0,03900019 0,04489674 ! protein phosphatase regulator activity GO:0019888 49 45 0,000 0,03900019 0,04488227 ! JNK cascade GO:0007254 45 45 0,000 0,03900019 0,04486781 ! SH3/SH2 adaptor activity GO:0005070 48 45 0,000 0,03900019 0,04485336 ! regulation of cell shape GO:0008360 46 45 0,000 0,03900019 0,04483892 ! epithelial tube morphogenesis GO:0060562 47 45 0,000 0,03900019 0,04482449 ! microbody part GO:0044438 46 45 0,000 0,03900019 0,04481006 GO:0044439|peroxisomal part, ! auxiliary transport protein activity GO:0015457 50 46 0,000 0,03985069 0,04577254 ! ATP synthesis coupled electron transport GO:0042773 46 46 0,000 0,03985069 0,04575782 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! microtubule binding GO:0008017 49 46 0,000 0,03985069 0,04574311 ! regulation of inflammatory response GO:0050727 46 46 0,000 0,03985069 0,04572841 ! transport vesicle GO:0030133 49 46 0,000 0,03985069 0,04571372 ! glutamine family amino acid metabolic process GO:0009064 49 46 0,000 0,03985069 0,04569904 ! synapse organization GO:0050808 51 46 0,000 0,03985069 0,04568437 ! nuclear matrix GO:0016363 49 46 0,000 0,03985069 0,04566971 ! striated muscle contraction GO:0006941 49 46 0,000 0,03985069 0,04565506 ! unsaturated fatty acid metabolic process GO:0033559 47 46 0,000 0,03985069 0,04564042 ! antioxidant activity GO:0016209 47 46 0,000 0,03985069 0,04562578 ! activation of caspase activity GO:0006919 49 46 0,000 0,03985069 0,04561116 ! aging GO:0007568 48 46 0,000 0,03985069 0,04559654 ! male sex differentiation GO:0046661 46 46 0,000 0,03985069 0,04558194 ! coated vesicle membrane GO:0030662 49 46 0,000 0,03985069 0,04556734 ! covalent chromatin modification GO:0016569 47 46 0,000 0,03985069 0,04555276 ! protein amino acid lipidation GO:0006497 50 47 0,000 0,0407005 0,04650927 ! stress-activated protein kinase signaling pathway GO:0031098 47 47 0,000 0,0407005 0,04649439 ! carbohydrate transport GO:0008643 47 47 0,000 0,0407005 0,04647952 ! proteasome complex GO:0000502 48 47 0,000 0,0407005 0,04646466 ! immunoglobulin mediated immune response GO:0016064 50 47 0,000 0,0407005 0,04644981 ! phosphatase regulator activity GO:0019208 51 47 0,000 0,0407005 0,04643497 ! vesicle organization GO:0016050 50 47 0,000 0,0407005 0,04642014 ! vascular process in circulatory system GO:0003018 49 47 0,000 0,0407005 0,04640532 ! cell cortex part GO:0044448 51 47 0,000 0,0407005 0,04639051 ! lipid modification GO:0030258 49 48 0,000 0,04154961 0,04734322 ! cytokine-mediated signaling pathway GO:0019221 49 48 0,000 0,04154961 0,04732812 ! morphogenesis of a branching structure GO:0001763 49 48 0,000 0,04154961 0,04731302 ! epidermal cell differentiation GO:0009913 51 48 0,000 0,04154961 0,04729794 ! mitochondrial transport GO:0006839 49 48 0,000 0,04154961 0,04728287 ! viral reproductive process GO:0022415 52 48 0,000 0,04154961 0,04726781 ! leukocyte migration GO:0050900 49 48 0,000 0,04154961 0,04725275 ! neuromuscular process GO:0050905 49 48 0,000 0,04154961 0,04723771 ! gastrulation GO:0007369 50 48 0,000 0,04154961 0,04722268 ! detection of abiotic stimulus GO:0009582 48 48 0,000 0,04154961 0,04720765 ! heterocycle catabolic process GO:0046700 53 48 0,000 0,04154961 0,04719264 ! B cell mediated immunity GO:0019724 51 48 0,000 0,04154961 0,04717763 ! transferase activity, transferring sulfur-containing groups GO:0016782 50 49 0,000 0,04239802 0,04812567 ! single-stranded DNA binding GO:0003697 49 49 0,000 0,04239802 0,04811037 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 54 49 0,000 0,04239802 0,04809509 ! intrinsic to endoplasmic reticulum membrane GO:0031227 50 49 0,000 0,04239802 0,04807982 ! ribonuclease activity GO:0004540 50 49 0,000 0,04239802 0,04806455 ! positive regulation of organelle organization GO:0010638 49 49 0,000 0,04239802 0,0480493 ! water-soluble vitamin metabolic process GO:0006767 50 49 0,000 0,04239802 0,04803406 ! lamellipodium GO:0030027 53 49 0,000 0,04239802 0,04801882 ! negative regulation of cell motion GO:0051271 51 49 0,000 0,04239802 0,0480036 ! nucleosome GO:0000786 49 49 0,000 0,04239802 0,04798838 ! kinetochore GO:0000776 50 49 0,000 0,04239802 0,04797318 ! membrane fusion GO:0006944 51 49 0,000 0,04239802 0,04795798 ! endocrine system development GO:0035270 49 49 0,000 0,04239802 0,04794279 ! glycosaminoglycan metabolic process GO:0030203 53 50 0,000 0,04324575 0,0488859 ! regulation of actin polymerization or depolymerization GO:0008064 51 50 0,000 0,04324575 0,04887043 ! basement membrane GO:0005604 51 50 0,000 0,04324575 0,04885497 ! regulation of intracellular transport GO:0032386 52 50 0,000 0,04324575 0,04883952 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,04324575 0,04882408 ! maintenance of location GO:0051235 51 50 0,000 0,04324575 0,04880865 ! nuclear periphery GO:0034399 53 50 0,000 0,04324575 0,04879323 ! cell redox homeostasis GO:0045454 51 50 0,000 0,04324575 0,04877782 ! integrin binding GO:0005178 53 50 0,000 0,04324575 0,04876241 ! regulation of DNA replication GO:0006275 56 50 0,000 0,04324575 0,04874702 ! amino acid activation GO:0043038 50 50 0,000 0,04324575 0,04873164 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of organelle localization GO:0051656 53 50 0,000 0,04324575 0,04871627 ! regulation of bone remodeling GO:0046850 55 51 0,000 0,04409278 0,04965478 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 52 51 0,000 0,04409278 0,04963913 ! late endosome GO:0005770 51 51 0,000 0,04409278 0,04962348 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 56 51 0,000 0,04409278 0,04960785 ! ligase activity, forming carbon-oxygen bonds GO:0016875 51 51 0,000 0,04409278 0,04959222 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! negative regulation of response to stimulus GO:0048585 55 51 0,000 0,04409278 0,04957661 ! skeletal muscle fiber development GO:0048741 54 51 0,000 0,04409278 0,04956101 ! lipoprotein biosynthetic process GO:0042158 54 51 0,000 0,04409278 0,04954541 ! heart morphogenesis GO:0003007 54 51 0,000 0,04409278 0,04952983 ! steroid hormone receptor activity GO:0003707 53 51 0,000 0,04409278 0,04951425 ! antiporter activity GO:0015297 52 51 0,000 0,04409278 0,04949868 ! respiratory electron transport chain GO:0022904 52 52 0,000 0,04493912 0,05043293 ! positive regulation of cell migration GO:0030335 55 52 0,000 0,04493912 0,05041709 ! Golgi-associated vesicle GO:0005798 55 52 0,000 0,04493912 0,05040125 ! sphingolipid metabolic process GO:0006665 53 52 0,000 0,04493912 0,05038543 ! cell maturation GO:0048469 55 52 0,000 0,04493912 0,05036961 ! regulation of protein polymerization GO:0032271 53 52 0,000 0,04493912 0,05035381 ! regulation of actin filament length GO:0030832 53 52 0,000 0,04493912 0,05033801 ! regulation of cell projection organization GO:0031344 55 52 0,000 0,04493912 0,05032223 ! chloride transport GO:0006821 53 52 0,000 0,04493912 0,05030645 ! positive regulation of caspase activity GO:0043280 55 52 0,000 0,04493912 0,05029069 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 55 52 0,000 0,04493912 0,05027493 ! regulation of muscle contraction GO:0006937 56 52 0,000 0,04493912 0,05025919 ! glucose catabolic process GO:0006007 52 52 0,000 0,04493912 0,05024345 ! generation of a signal involved in cell-cell signaling GO:0003001 54 52 0,000 0,04493912 0,05022773 ! small ribosomal subunit GO:0015935 52 52 0,000 0,04493912 0,05021201 ! cytokine receptor activity GO:0004896 53 52 0,000 0,04493912 0,05019631 ! activation of phospholipase C activity GO:0007202 55 53 0,000 0,04578477 0,05112489 GO:0010863|positive regulation of phospholipase C activity, ! nucleoside monophosphate metabolic process GO:0009123 58 53 0,000 0,04578477 0,05110891 ! nucleoside metabolic process GO:0009116 61 53 0,000 0,04578477 0,05109294 ! N-acetyltransferase activity GO:0008080 54 53 0,000 0,04578477 0,05107697 ! synaptic vesicle GO:0008021 57 53 0,000 0,04578477 0,05106102 ! pyridoxal phosphate binding GO:0030170 56 53 0,000 0,04578477 0,05104508 GO:0070279|vitamin B6 binding, ! viral reproduction GO:0016032 57 53 0,000 0,04578477 0,05102915 ! cell projection assembly GO:0030031 56 53 0,000 0,04578477 0,05101323 ! embryonic skeletal system development GO:0048706 54 53 0,000 0,04578477 0,05099732 ! proton transport GO:0015992 53 53 0,000 0,04578477 0,05098141 ! mRNA binding GO:0003729 55 53 0,000 0,04578477 0,05096552 ! single fertilization GO:0007338 55 53 0,000 0,04578477 0,05094964 ! axon GO:0030424 58 54 0,000 0,04662972 0,05187375 ! heat shock protein binding GO:0031072 54 54 0,000 0,04662972 0,05185759 ! regulation of neurotransmitter levels GO:0001505 60 54 0,000 0,04662972 0,05184145 ! double-stranded DNA binding GO:0003690 55 54 0,000 0,04662972 0,05182531 ! positive regulation of phospholipase activity GO:0010518 56 54 0,000 0,04662972 0,05180919 ! growth factor receptor binding GO:0070851 56 54 0,000 0,04662972 0,05179307 ! regulation of protein catabolic process GO:0042176 57 54 0,000 0,04662972 0,05177697 ! regulation of tissue remodeling GO:0034103 58 54 0,000 0,04662972 0,05176087 ! regulation of cellular component size GO:0032535 56 55 0,000 0,04747399 0,05268167 ! response to peptide hormone stimulus GO:0043434 60 55 0,000 0,04747399 0,0526653 ! hydrogen transport GO:0006818 55 55 0,000 0,04747399 0,05264895 ! glycerophospholipid biosynthetic process GO:0046474 59 55 0,000 0,04747399 0,0526326 ! large ribosomal subunit GO:0015934 56 55 0,000 0,04747399 0,05261626 ! protein amino acid autophosphorylation GO:0046777 57 55 0,000 0,04747399 0,05259994 ! positive regulation of secretion GO:0051047 60 56 0,000 0,04831756 0,05351799 ! regulation of mitosis GO:0007088 56 56 0,000 0,04831756 0,0535014 GO:0051783|regulation of nuclear division, ! actin filament organization GO:0007015 59 56 0,000 0,04831756 0,05348481 ! regulation of phospholipase activity GO:0010517 58 56 0,000 0,04831756 0,05346824 ! coenzyme biosynthetic process GO:0009108 59 56 0,000 0,04831756 0,05345168 ! cellular amino acid catabolic process GO:0009063 59 56 0,000 0,04831756 0,05343512 ! cartilage development GO:0051216 59 56 0,000 0,04831756 0,05341858 ! regulation of protein complex assembly GO:0043254 57 56 0,000 0,04831756 0,05340205 ! receptor signaling protein serine/threonine kinase activity GO:0004702 58 56 0,000 0,04831756 0,05338552 ! mesoderm development GO:0007498 57 56 0,000 0,04831756 0,05336901 ! camera-type eye development GO:0043010 59 56 0,000 0,04831756 0,05335251 ! regulation of transcription factor activity GO:0051090 59 57 0,000 0,04916045 0,05426645 GO:0090046|regulation of transcription regulator activity, ! ear development GO:0043583 60 57 0,000 0,04916045 0,05424968 ! positive regulation of T cell activation GO:0050870 62 57 0,000 0,04916045 0,05423292 ! kidney development GO:0001822 60 57 0,000 0,04916045 0,05421617 ! positive regulation of lipase activity GO:0060193 59 57 0,000 0,04916045 0,05419943 ! integrin-mediated signaling pathway GO:0007229 61 57 0,000 0,04916045 0,0541827 ! adult behavior GO:0030534 60 57 0,000 0,04916045 0,05416598 ! myosin complex GO:0016459 59 57 0,000 0,04916045 0,05414928 ! regulation of angiogenesis GO:0045765 60 58 0,000 0,05000264 0,05505996 ! lysosomal membrane GO:0005765 59 58 0,000 0,05000264 0,05504298 ! extracellular matrix organization GO:0030198 59 58 0,000 0,05000264 0,05502602 ! positive regulation of cell motion GO:0051272 61 58 0,000 0,05000264 0,05500907 ! homeostasis of number of cells GO:0048872 62 58 0,000 0,05000264 0,05499213 ! regulation of vesicle-mediated transport GO:0060627 60 58 0,000 0,05000264 0,0549752 ! detection of external stimulus GO:0009581 59 58 0,000 0,05000264 0,05495828 ! secondary metabolic process GO:0019748 59 58 0,000 0,05000264 0,05494137 ! translation initiation factor activity GO:0003743 58 58 0,000 0,05000264 0,05492447 ! dendrite GO:0030425 61 59 0,000 0,05084415 0,05583163 ! molecular adaptor activity GO:0060090 65 59 0,000 0,05084415 0,05581447 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 60 59 0,000 0,05084415 0,05579731 GO:0051213|dioxygenase activity, ! embryonic limb morphogenesis GO:0030326 63 59 0,000 0,05084415 0,05578017 GO:0035113|embryonic appendage morphogenesis, ! ubiquitin thiolesterase activity GO:0004221 62 59 0,000 0,05084415 0,05576304 ! regulation of heart contraction GO:0008016 62 59 0,000 0,05084415 0,05574592 ! copper ion binding GO:0005507 61 59 0,000 0,05084415 0,05572881 ! activation of immune response GO:0002253 68 59 0,000 0,05084415 0,05571171 ! aminoglycan metabolic process GO:0006022 62 59 0,000 0,05084415 0,05569462 ! amine transmembrane transporter activity GO:0005275 59 59 0,000 0,05084415 0,05567754 ! chromatin remodeling complex GO:0016585 61 59 0,000 0,05084415 0,05566047 ! cell soma GO:0043025 63 59 0,000 0,05084415 0,05564341 ! regulation of homeostatic process GO:0032844 68 59 0,000 0,05084415 0,05562637 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 61 60 0,000 0,05168497 0,05652895 ! multicellular organism reproduction GO:0032504 62 60 0,000 0,05168497 0,05651164 GO:0048609|reproductive process in a multicellular organism, ! occluding junction GO:0070160 60 60 0,000 0,05168497 0,05649435 GO:0005923|tight junction, ! myeloid cell differentiation GO:0030099 64 60 0,000 0,05168497 0,05647706 ! oxygen and reactive oxygen species metabolic process GO:0006800 60 60 0,000 0,05168497 0,05645978 ! regulation of cytokine biosynthetic process GO:0042035 63 60 0,000 0,05168497 0,05644252 ! lymphocyte mediated immunity GO:0002449 63 60 0,000 0,05168497 0,05642526 ! chloride channel activity GO:0005254 61 60 0,000 0,05168497 0,05640802 ! fertilization GO:0009566 64 61 0,000 0,0525251 0,05730741 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 65 61 0,000 0,0525251 0,0572899 ! gonad development GO:0008406 61 61 0,000 0,0525251 0,05727241 ! protein maturation by peptide bond cleavage GO:0051605 64 61 0,000 0,0525251 0,05725493 ! regulation of immune effector process GO:0002697 65 61 0,000 0,0525251 0,05723745 ! amine catabolic process GO:0009310 68 62 0,000 0,05336455 0,05813447 ! phosphoinositide metabolic process GO:0030384 66 62 0,000 0,05336455 0,05811674 ! glycerolipid biosynthetic process GO:0045017 66 62 0,000 0,05336455 0,05809902 ! coated membrane GO:0048475 67 62 0,000 0,05336455 0,05808132 GO:0030117|membrane coat, ! hexose catabolic process GO:0019320 63 62 0,000 0,05336455 0,05806362 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 63 62 0,000 0,05336455 0,05804593 ! extracellular ligand-gated ion channel activity GO:0005230 67 62 0,000 0,05336455 0,05802826 ! germ cell development GO:0007281 62 62 0,000 0,05336455 0,05801059 ! ligand-dependent nuclear receptor activity GO:0004879 65 62 0,000 0,05336455 0,05799294 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 70 63 0,000 0,0542033 0,05888652 ! mitochondrial respiratory chain GO:0005746 65 63 0,000 0,0542033 0,05886861 ! negative regulation of ligase activity GO:0051352 64 63 0,000 0,0542033 0,05885072 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein oligomerization GO:0051259 64 63 0,000 0,0542033 0,05883283 ! transition metal ion transport GO:0000041 65 63 0,000 0,0542033 0,05881495 ! appendage morphogenesis GO:0035107 67 63 0,000 0,0542033 0,05879708 GO:0035108|limb morphogenesis, ! activation of MAPK activity GO:0000187 69 63 0,000 0,0542033 0,05877923 ! cellular defense response GO:0006968 64 63 0,000 0,0542033 0,05876138 ! B cell activation GO:0042113 66 63 0,000 0,0542033 0,05874355 ! antigen processing and presentation GO:0019882 64 63 0,000 0,0542033 0,05872573 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 65 63 0,000 0,0542033 0,05870792 ! microtubule motor activity GO:0003777 67 63 0,000 0,0542033 0,05869012 ! organelle localization GO:0051640 66 63 0,000 0,0542033 0,05867233 ! transforming growth factor beta receptor signaling pathway GO:0007179 67 64 0,000 0,05504138 0,05956144 ! lung development GO:0030324 65 64 0,000 0,05504138 0,0595434 ! respiratory chain GO:0070469 66 64 0,000 0,05504138 0,05952537 ! developmental maturation GO:0021700 67 64 0,000 0,05504138 0,05950734 ! amino acid transport GO:0006865 64 64 0,000 0,05504138 0,05948933 ! anion channel activity GO:0005253 65 64 0,000 0,05504138 0,05947133 ! cellular hormone metabolic process GO:0034754 65 65 0,000 0,05587876 0,06035785 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 65 0,000 0,05587876 0,0603396 ! nuclear pore GO:0005643 69 65 0,000 0,05587876 0,06032136 ! regulation of MAPKKK cascade GO:0043408 72 65 0,000 0,05587876 0,06030313 ! rhythmic process GO:0048511 66 65 0,000 0,05587876 0,06028491 ! regulation of lipase activity GO:0060191 67 65 0,000 0,05587876 0,06026671 ! adaptive immune response GO:0002250 68 65 0,000 0,05587876 0,06024851 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 69 65 0,000 0,05587876 0,06023032 GO:0060173|limb development, ! skeletal system morphogenesis GO:0048705 66 65 0,000 0,05587876 0,06021215 ! lipoprotein metabolic process GO:0042157 68 65 0,000 0,05587876 0,06019399 ! DNA-dependent DNA replication GO:0006261 66 65 0,000 0,05587876 0,06017583 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 71 66 0,000 0,05671547 0,06105846 ! endoplasmic reticulum lumen GO:0005788 66 66 0,000 0,05671547 0,06104006 ! urogenital system development GO:0001655 69 66 0,000 0,05671547 0,06102167 ! diacylglycerol binding GO:0019992 71 66 0,000 0,05671547 0,06100329 ! amine binding GO:0043176 70 66 0,000 0,05671547 0,06098492 ! response to nutrient GO:0007584 67 66 0,000 0,05671547 0,06096656 ! acetyltransferase activity GO:0016407 68 66 0,000 0,05671547 0,06094822 ! respiratory tube development GO:0030323 68 67 0,000 0,05755148 0,06182802 ! mRNA transport GO:0051028 70 67 0,000 0,05755148 0,06180943 ! intracellular protein transmembrane transport GO:0065002 70 67 0,000 0,05755148 0,06179084 ! activation of protein kinase activity GO:0032147 70 67 0,000 0,05755148 0,06177227 ! regulation of caspase activity GO:0043281 70 67 0,000 0,05755148 0,06175371 ! Ras GTPase binding GO:0017016 70 67 0,000 0,05755148 0,06173516 ! humoral immune response GO:0006959 70 67 0,000 0,05755148 0,06171662 ! nucleosome assembly GO:0006334 69 67 0,000 0,05755148 0,06169809 ! muscle cell differentiation GO:0042692 68 68 0,000 0,05838682 0,06257483 ! fatty acid biosynthetic process GO:0006633 70 68 0,000 0,05838682 0,06255605 ! protein import into nucleus GO:0006606 72 68 0,000 0,05838682 0,06253729 ! lymphocyte differentiation GO:0030098 75 68 0,000 0,05838682 0,06251854 ! regulation of actin cytoskeleton organization GO:0032956 74 68 0,000 0,05838682 0,0624998 ! protein-DNA complex GO:0032993 69 68 0,000 0,05838682 0,06248107 ! learning or memory GO:0007611 72 68 0,000 0,05838682 0,06246235 ! chloride ion binding GO:0031404 70 68 0,000 0,05838682 0,06244364 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 71 68 0,000 0,05838682 0,06242495 ! chromatin assembly GO:0031497 70 68 0,000 0,05838682 0,06240626 ! leukocyte mediated immunity GO:0002443 71 68 0,000 0,05838682 0,06238759 ! extrinsic to membrane GO:0019898 68 68 0,000 0,05838682 0,06236893 ! calcium channel activity GO:0005262 73 68 0,000 0,05838682 0,06235027 ! ribonucleoprotein complex assembly GO:0022618 69 68 0,000 0,05838682 0,06233163 ! respiratory system development GO:0060541 69 68 0,000 0,05838682 0,06231301 ! N-acyltransferase activity GO:0016410 69 68 0,000 0,05838682 0,06229439 ! regulation of endopeptidase activity GO:0052548 72 69 0,000 0,05922147 0,06316603 ! eye development GO:0001654 74 69 0,000 0,05922147 0,06314716 ! sarcomere GO:0030017 75 69 0,000 0,05922147 0,06312831 ! cAMP-mediated signaling GO:0019933 72 69 0,000 0,05922147 0,06310948 ! axon guidance GO:0007411 74 69 0,000 0,05922147 0,06309065 ! focal adhesion GO:0005925 75 69 0,000 0,05922147 0,06307183 ! regulation of DNA binding GO:0051101 72 70 0,000 0,06005543 0,06394095 ! carboxylic acid transmembrane transporter activity GO:0046943 71 70 0,000 0,06005543 0,06392189 ! early endosome GO:0005769 79 70 0,000 0,06005543 0,06390284 ! response to hypoxia GO:0001666 76 70 0,000 0,06005543 0,06388381 ! nuclear import GO:0051170 74 70 0,000 0,06005543 0,06386478 ! female pregnancy GO:0007565 71 70 0,000 0,06005543 0,06384577 ! rRNA processing GO:0006364 70 70 0,000 0,06005543 0,06382677 ! cytosolic ribosome GO:0022626 70 70 0,000 0,06005543 0,06380778 ! cell cortex GO:0005938 74 70 0,000 0,06005543 0,0637888 ! cell-matrix adhesion GO:0007160 76 71 0,000 0,06088872 0,06465466 ! FAD binding GO:0050660 72 71 0,000 0,06088872 0,06463544 ! response to oxygen levels GO:0070482 77 71 0,000 0,06088872 0,06461623 ! mitochondrial outer membrane GO:0005741 75 71 0,000 0,06088872 0,06459703 ! defense response to bacterium GO:0042742 71 71 0,000 0,06088872 0,06457785 ! steroid biosynthetic process GO:0006694 72 71 0,000 0,06088872 0,06455867 ! monosaccharide catabolic process GO:0046365 72 71 0,000 0,06088872 0,06453951 ! regulation of synaptic transmission GO:0050804 73 71 0,000 0,06088872 0,06452036 ! reproductive structure development GO:0048608 71 71 0,000 0,06088872 0,06450122 ! neurotransmitter transport GO:0006836 73 71 0,000 0,06088872 0,06448209 ! regulation of actin filament-based process GO:0032970 77 71 0,000 0,06088872 0,06446297 ! organic acid transmembrane transporter activity GO:0005342 72 71 0,000 0,06088872 0,06444387 ! phospholipase activity GO:0004620 75 71 0,000 0,06088872 0,06442477 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 75 71 0,000 0,06088872 0,06440569 ! cell projection part GO:0044463 75 71 0,000 0,06088872 0,06438662 ! amine biosynthetic process GO:0009309 75 72 0,000 0,06172132 0,06524773 ! meiosis GO:0007126 73 72 0,000 0,06172132 0,06522842 GO:0051327|M phase of meiotic cell cycle, ! elevation of cytosolic calcium ion concentration GO:0007204 77 72 0,000 0,06172132 0,06520912 ! acute inflammatory response GO:0002526 76 72 0,000 0,06172132 0,06518983 ! cholesterol metabolic process GO:0008203 74 72 0,000 0,06172132 0,06517056 ! lipid transporter activity GO:0005319 77 72 0,000 0,06172132 0,06515129 ! cell-substrate adherens junction GO:0005924 78 72 0,000 0,06172132 0,06513204 ! negative regulation of transport GO:0051051 74 73 0,000 0,06255324 0,06599043 ! vacuolar membrane GO:0005774 74 73 0,000 0,06255324 0,06597094 ! rRNA metabolic process GO:0016072 73 73 0,000 0,06255324 0,06595147 ! meiotic cell cycle GO:0051321 75 73 0,000 0,06255324 0,065932 ! regulation of protein transport GO:0051223 77 73 0,000 0,06255324 0,06591255 GO:0070201|regulation of establishment of protein localization, ! exopeptidase activity GO:0008238 78 73 0,000 0,06255324 0,0658931 ! cytosolic calcium ion homeostasis GO:0051480 78 73 0,000 0,06255324 0,06587367 ! nucleosome organization GO:0034728 76 74 0,000 0,06338448 0,06672936 ! neuropeptide signaling pathway GO:0007218 79 74 0,000 0,06338448 0,06670969 ! pore complex GO:0046930 78 74 0,000 0,06338448 0,06669003 ! regulation of peptidase activity GO:0052547 78 74 0,000 0,06338448 0,06667039 ! protein localization in nucleus GO:0034504 78 74 0,000 0,06338448 0,06665076 ! myofibril GO:0030016 80 74 0,000 0,06338448 0,06663114 ! regulation of blood pressure GO:0008217 76 74 0,000 0,06338448 0,06661153 ! apical junction complex GO:0043296 74 74 0,000 0,06338448 0,06659193 ! cellular carbohydrate catabolic process GO:0044275 75 74 0,000 0,06338448 0,06657235 ! development of primary sexual characteristics GO:0045137 74 74 0,000 0,06338448 0,06655277 ! membrane raft GO:0045121 78 74 0,000 0,06338448 0,06653321 ! regulation of Rho protein signal transduction GO:0035023 79 74 0,000 0,06338448 0,06651366 ! cellular response to hormone stimulus GO:0032870 81 74 0,000 0,06338448 0,06649412 ! serine-type endopeptidase inhibitor activity GO:0004867 75 74 0,000 0,06338448 0,06647459 ! nuclear chromosome part GO:0044454 76 74 0,000 0,06338448 0,06645507 ! response to drug GO:0042493 77 75 0,000 0,06421504 0,06730611 ! small GTPase binding GO:0031267 78 75 0,000 0,06421504 0,06728636 ! regulation of catabolic process GO:0009894 80 75 0,000 0,06421504 0,06726662 ! cell-substrate junction GO:0030055 82 75 0,000 0,06421504 0,06724689 ! establishment of RNA localization GO:0051236 78 75 0,000 0,06421504 0,06722718 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! membrane lipid biosynthetic process GO:0046467 77 75 0,000 0,06421504 0,06720747 ! tube morphogenesis GO:0035239 79 75 0,000 0,06421504 0,06718778 ! cellular lipid catabolic process GO:0044242 77 75 0,000 0,06421504 0,0671681 ! cysteine-type endopeptidase activity GO:0004197 75 75 0,000 0,06421504 0,06714843 ! structural constituent of cytoskeleton GO:0005200 81 75 0,000 0,06421504 0,06712878 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 80 76 0,000 0,06504492 0,06797641 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 76 76 0,000 0,06504492 0,06795652 ! vitamin metabolic process GO:0006766 77 76 0,000 0,06504492 0,06793665 ! inorganic anion transport GO:0015698 78 76 0,000 0,06504492 0,06791678 ! chromosome, centromeric region GO:0000775 78 76 0,000 0,06504492 0,06789693 ! apicolateral plasma membrane GO:0016327 76 76 0,000 0,06504492 0,06787709 ! T cell activation GO:0042110 82 76 0,000 0,06504492 0,06785726 ! digestion GO:0007586 80 76 0,000 0,06504492 0,06783744 ! cell-substrate adhesion GO:0031589 81 76 0,000 0,06504492 0,06781764 ! cilium GO:0005929 77 76 0,000 0,06504492 0,06779784 ! contractile fiber part GO:0044449 82 76 0,000 0,06504492 0,06777806 ! regulation of adenylate cyclase activity GO:0045761 80 77 0,000 0,06587412 0,06862208 ! RNA localization GO:0006403 80 77 0,000 0,06587412 0,06860206 ! nuclear speck GO:0016607 80 77 0,000 0,06587412 0,06858206 ! G-protein-coupled receptor binding GO:0001664 78 77 0,000 0,06587412 0,06856207 ! regulation of transmission of nerve impulse GO:0051969 79 77 0,000 0,06587412 0,0685421 ! hydrogen ion transmembrane transporter activity GO:0015078 78 77 0,000 0,06587412 0,06852213 ! extracellular matrix structural constituent GO:0005201 80 77 0,000 0,06587412 0,06850218 ! vacuolar part GO:0044437 78 77 0,000 0,06587412 0,06848223 ! thiolester hydrolase activity GO:0016790 81 78 0,000 0,06670264 0,06932338 ! potassium channel complex GO:0034705 81 78 0,000 0,06670264 0,06930321 GO:0008076|voltage-gated potassium channel complex, ! regulation of cell adhesion GO:0030155 82 78 0,000 0,06670264 0,06928305 ! cofactor biosynthetic process GO:0051188 81 78 0,000 0,06670264 0,0692629 ! blood coagulation GO:0007596 81 78 0,000 0,06670264 0,06924277 GO:0050817|coagulation, ! phospholipid biosynthetic process GO:0008654 83 79 0,000 0,06753048 0,07008176 ! biogenic amine metabolic process GO:0006576 85 79 0,000 0,06753048 0,0700614 ! phosphoric diester hydrolase activity GO:0008081 82 79 0,000 0,06753048 0,07004106 ! positive regulation of MAP kinase activity GO:0043406 85 79 0,000 0,06753048 0,07002072 ! regulation of cyclase activity GO:0031279 82 79 0,000 0,06753048 0,07000039 ! regulation of neuron differentiation GO:0045664 82 79 0,000 0,06753048 0,06998008 ! regulation of T cell activation GO:0050863 84 79 0,000 0,06753048 0,06995978 ! regulation of cAMP biosynthetic process GO:0030817 82 79 0,000 0,06753048 0,06993949 ! exocytosis GO:0006887 81 79 0,000 0,06753048 0,06991921 ! nitrogen compound catabolic process GO:0044270 89 79 0,000 0,06753048 0,06989894 ! regulation of protein localization GO:0032880 83 79 0,000 0,06753048 0,06987869 ! alcohol catabolic process GO:0046164 83 80 0,000 0,06835765 0,07071412 ! GTPase binding GO:0051020 83 80 0,000 0,06835765 0,07069365 ! regulation of Ras GTPase activity GO:0032318 84 80 0,000 0,06835765 0,07067318 ! regulation of lyase activity GO:0051339 83 80 0,000 0,06835765 0,07065272 ! ATP biosynthetic process GO:0006754 85 80 0,000 0,06835765 0,07063228 ! one-carbon metabolic process GO:0006730 87 80 0,000 0,06835765 0,07061185 ! monooxygenase activity GO:0004497 82 80 0,000 0,06835765 0,07059143 ! contractile fiber GO:0043292 86 80 0,000 0,06835765 0,07057102 ! protein ubiquitination GO:0016567 86 80 0,000 0,06835765 0,07055062 ! ossification GO:0001503 85 81 0,000 0,06918414 0,071383 ! cellular carbohydrate biosynthetic process GO:0034637 83 81 0,000 0,06918414 0,07136238 ! sterol metabolic process GO:0016125 83 81 0,000 0,06918414 0,07134177 ! regulation of cAMP metabolic process GO:0030814 84 81 0,000 0,06918414 0,07132117 ! protein binding, bridging GO:0030674 86 81 0,000 0,06918414 0,07130059 ! regulation of neurological system process GO:0031644 83 81 0,000 0,06918414 0,07128002 ! protein transporter activity GO:0008565 85 82 0,000 0,07000995 0,07211004 ! positive regulation of immune response GO:0050778 91 82 0,000 0,07000995 0,07208925 ! regulation of defense response GO:0031347 82 82 0,000 0,07000995 0,07206847 ! bone development GO:0060348 86 82 0,000 0,07000995 0,0720477 ! carboxylesterase activity GO:0004091 86 82 0,000 0,07000995 0,07202694 ! mitochondrion organization GO:0007005 86 83 0,000 0,07083508 0,07285486 ! organelle outer membrane GO:0031968 87 83 0,000 0,07083508 0,07283388 ! cell leading edge GO:0031252 90 83 0,000 0,07083508 0,07281292 ! SH3 domain binding GO:0017124 97 83 0,000 0,07083508 0,07279196 ! hemostasis GO:0007599 86 83 0,000 0,07083508 0,07277102 ! oxidative phosphorylation GO:0006119 83 83 0,000 0,07083508 0,07275009 ! heparin binding GO:0008201 90 83 0,000 0,07083508 0,07272918 ! amine transport GO:0015837 83 83 0,000 0,07083508 0,07270827 ! extracellular matrix part GO:0044420 85 83 0,000 0,07083508 0,07268738 ! phosphoinositide binding GO:0035091 90 83 0,000 0,07083508 0,0726665 ! regulation of nucleotide biosynthetic process GO:0030808 87 84 0,000 0,07165954 0,07349116 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! Ras GTPase activator activity GO:0005099 89 84 0,000 0,07165954 0,07347006 ! regulation of membrane potential GO:0042391 92 84 0,000 0,07165954 0,07344897 ! perinuclear region of cytoplasm GO:0048471 91 85 0,000 0,07248332 0,07427201 ! cellular respiration GO:0045333 85 85 0,000 0,07248332 0,0742507 ! transmembrane receptor protein kinase activity GO:0019199 88 85 0,000 0,07248332 0,07422941 ! outer membrane GO:0019867 89 85 0,000 0,07248332 0,07420813 ! neurotransmitter receptor activity GO:0030594 86 85 0,000 0,07248332 0,07418686 ! leukocyte differentiation GO:0002521 95 86 0,000 0,07330643 0,07500781 ! Golgi vesicle transport GO:0048193 86 86 0,000 0,07330643 0,07498633 ! pigment granule GO:0048770 90 86 0,000 0,07330643 0,07496485 GO:0042470|melanosome, ! neurotransmitter binding GO:0042165 88 86 0,000 0,07330643 0,07494339 ! anion binding GO:0043168 89 86 0,000 0,07330643 0,07492194 ! sex differentiation GO:0007548 86 86 0,000 0,07330643 0,07490051 ! UDP-glycosyltransferase activity GO:0008194 91 86 0,000 0,07330643 0,07487908 ! spindle GO:0005819 89 87 0,000 0,07412887 0,07569751 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 93 87 0,000 0,07412887 0,07567587 ! regulation of cyclic nucleotide metabolic process GO:0030799 90 87 0,000 0,07412887 0,07565424 ! protein processing GO:0016485 92 87 0,000 0,07412887 0,07563262 ! ATP-dependent helicase activity GO:0008026 92 88 0,000 0,07495063 0,07644921 GO:0070035|purine NTP-dependent helicase activity, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 89 88 0,000 0,07495063 0,07642738 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 89 88 0,000 0,07495063 0,07640556 ! skeletal muscle tissue development GO:0007519 92 88 0,000 0,07495063 0,07638376 GO:0060538|skeletal muscle organ development, ! lipase activity GO:0016298 92 88 0,000 0,07495063 0,07636196 ! detection of stimulus GO:0051606 90 88 0,000 0,07495063 0,07634018 ! carboxylic acid catabolic process GO:0046395 93 89 0,000 0,07577171 0,07715449 GO:0016054|organic acid catabolic process, ! sulfur metabolic process GO:0006790 90 89 0,000 0,07577171 0,07713249 ! negative regulation of multicellular organismal process GO:0051241 93 89 0,000 0,07577171 0,07711051 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 92 89 0,000 0,07577171 0,07708854 ! regulation of binding GO:0051098 93 90 0,000 0,07659213 0,07790102 ! intermediate filament GO:0005882 92 90 0,000 0,07659213 0,07787884 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 95 90 0,000 0,07659213 0,07785667 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! nuclear membrane GO:0031965 92 90 0,000 0,07659213 0,07783452 ! external side of plasma membrane GO:0009897 99 90 0,000 0,07659213 0,07781237 ! growth factor binding GO:0019838 92 90 0,000 0,07659213 0,07779024 ! regulation of nucleotide metabolic process GO:0006140 93 90 0,000 0,07659213 0,07776812 ! adherens junction GO:0005912 96 90 0,000 0,07659213 0,07774602 ! ATP metabolic process GO:0046034 96 91 0,000 0,07741187 0,07855578 ! homophilic cell adhesion GO:0007156 93 91 0,000 0,07741187 0,07853346 ! ribonucleoside triphosphate biosynthetic process GO:0009201 97 91 0,000 0,07741187 0,07851116 ! protein modification by small protein conjugation GO:0032446 98 91 0,000 0,07741187 0,07848887 ! forebrain development GO:0030900 95 91 0,000 0,07741187 0,07846659 ! carbohydrate biosynthetic process GO:0016051 93 91 0,000 0,07741187 0,07844432 ! apical plasma membrane GO:0016324 96 91 0,000 0,07741187 0,07842207 ! intermediate filament cytoskeleton GO:0045111 93 91 0,000 0,07741187 0,07839983 ! structure-specific DNA binding GO:0043566 93 92 0,000 0,07823094 0,07920689 ! angiogenesis GO:0001525 95 92 0,000 0,07823094 0,07918443 ! glycerophospholipid metabolic process GO:0006650 98 92 0,000 0,07823094 0,079162 ! nucleoside triphosphate biosynthetic process GO:0009142 98 92 0,000 0,07823094 0,07913957 ! clathrin-coated vesicle GO:0030136 100 92 0,000 0,07823094 0,07911716 ! gland development GO:0048732 95 92 0,000 0,07823094 0,07909476 ! anatomical structure homeostasis GO:0060249 96 93 0,000 0,07904934 0,07989957 ! receptor complex GO:0043235 97 93 0,000 0,07904934 0,07987696 ! voltage-gated potassium channel activity GO:0005249 99 93 0,000 0,07904934 0,07985437 ! hormone metabolic process GO:0042445 96 93 0,000 0,07904934 0,07983178 ! translational elongation GO:0006414 97 94 0,000 0,07986707 0,0806348 ! metalloendopeptidase activity GO:0004222 105 94 0,000 0,07986707 0,08061201 ! carbohydrate catabolic process GO:0016052 95 94 0,000 0,07986707 0,08058923 ! protein maturation GO:0051604 99 94 0,000 0,07986707 0,08056647 ! solute:cation symporter activity GO:0015294 95 94 0,000 0,07986707 0,08054371 ! in utero embryonic development GO:0001701 97 95 0,000 0,08068412 0,08134472 ! carboxylic acid binding GO:0031406 99 95 0,000 0,08068412 0,08132176 ! regulation of response to external stimulus GO:0032101 97 95 0,000 0,08068412 0,08129882 ! response to virus GO:0009615 102 95 0,000 0,08068412 0,08127588 ! peroxisome GO:0005777 97 96 0,000 0,08150051 0,08207511 GO:0042579|microbody, ! integral to organelle membrane GO:0031301 96 96 0,000 0,08150051 0,08205197 ! Wnt receptor signaling pathway GO:0016055 104 96 0,000 0,08150051 0,08202884 ! translation factor activity, nucleic acid binding GO:0008135 99 96 0,000 0,08150051 0,08200573 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 97 96 0,000 0,08150051 0,08198263 ! cell fate commitment GO:0045165 98 96 0,000 0,08150051 0,08195954 ! response to nutrient levels GO:0031667 98 96 0,000 0,08150051 0,08193647 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 101 97 0,000 0,08231623 0,08273326 ! microtubule associated complex GO:0005875 104 97 0,000 0,08231623 0,08270998 ! peptidyl-amino acid modification GO:0018193 99 97 0,000 0,08231623 0,08268671 ! anchoring junction GO:0070161 103 97 0,000 0,08231623 0,08266346 ! reproductive developmental process GO:0003006 97 97 0,000 0,08231623 0,08264022 ! regulation of GTPase activity GO:0043087 104 97 0,000 0,08231623 0,08261699 ! unfolded protein binding GO:0051082 100 98 0,000 0,08313128 0,08341158 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 99 98 0,000 0,08313128 0,08338815 ! polysaccharide metabolic process GO:0005976 102 98 0,000 0,08313128 0,08336473 ! protein modification by small protein conjugation or removal GO:0070647 105 98 0,000 0,08313128 0,08334133 ! nuclear chromosome GO:0000228 102 99 0,000 0,08394566 0,08413415 ! regulation of cellular component biogenesis GO:0044087 106 99 0,000 0,08394566 0,08411054 ! anterior/posterior pattern formation GO:0009952 102 99 0,000 0,08394566 0,08408695 ! Ras protein signal transduction GO:0007265 105 99 0,000 0,08394566 0,08406337 ! electron transport chain GO:0022900 102 100 0,000 0,08475938 0,08485443 ! protein polymerization GO:0051258 114 100 0,000 0,08475938 0,08483064 ! cytokine binding GO:0019955 101 100 0,000 0,08475938 0,08480688 ! regulation of cell morphogenesis GO:0022604 104 100 0,000 0,08475938 0,08478312 ! chromatin assembly or disassembly GO:0006333 104 100 0,000 0,08475938 0,08475938