pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/60598-7-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! alcohol catabolic process GO:0046164 142 87 5,000 1,554E-10 3,795E-07 ! polyol catabolic process GO:0046174 9 5 2,000 6,62E-09 8,086E-06 GO:0019405|alditol catabolic process, ! substrate-bound cell migration, cell extension GO:0006930 6 5 2,000 6,62E-09 5,391E-06 ! neural plate morphogenesis GO:0001839 7 5 2,000 6,62E-09 4,043E-06 ! neural plate development GO:0001840 9 6 2,000 1,323E-08 6,465E-06 ! glycolysis GO:0006096 71 46 3,000 8,594E-08 3,499E-05 ! substrate-bound cell migration GO:0006929 14 11 2,000 1,088E-07 3,798E-05 ! establishment of cell polarity GO:0030010 21 12 2,000 1,45E-07 4,428E-05 ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 1,884E-07 5,114E-05 ! glucose catabolic process GO:0006007 88 56 3,000 1,922E-07 4,696E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 2,066E-07 4,588E-05 ! fructose metabolic process GO:0006000 25 16 2,000 3,682E-07 7,496E-05 ! hexose catabolic process GO:0019320 113 68 3,000 4,23E-07 7,949E-05 ! neural crest cell migration GO:0001755 41 18 2,000 5,359E-07 9,351E-05 ! regulation of actin cytoskeleton organization GO:0032956 167 76 3,000 6,63E-07 1,08E-04 ! monosaccharide catabolic process GO:0046365 125 77 3,000 6,989E-07 1,067E-04 ! regulation of actin filament-based process GO:0032970 170 79 3,000 7,75E-07 1,114E-04 ! positive regulation of cytoskeleton organization GO:0051495 52 24 2,000 1,324E-06 1,797E-04 ! neural crest cell development GO:0014032 59 26 2,000 1,699E-06 2,185E-04 GO:0014033|neural crest cell differentiation, ! alditol metabolic process GO:0019400 44 26 2,000 1,699E-06 2,076E-04 ! sperm motility GO:0030317 37 28 2,000 2,138E-06 2,488E-04 ! primary neural tube formation GO:0014020 61 29 2,000 2,384E-06 2,647E-04 ! regulation of actin filament depolymerization GO:0030834 67 30 2,000 2,647E-06 2,811E-04 ! hexose biosynthetic process GO:0019319 53 32 2,000 3,23E-06 3,287E-04 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 4,638E-06 4,532E-04 ! neural tube formation GO:0001841 79 38 2,000 5,473E-06 5,142E-04 ! Rho protein signal transduction GO:0007266 88 40 2,000 6,402E-06 5,792E-04 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 6,903E-06 6,023E-04 ! mesenchymal cell development GO:0014031 94 41 2,000 6,903E-06 5,815E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! embryonic epithelial tube formation GO:0001838 85 41 2,000 6,903E-06 5,621E-04 ! alcohol biosynthetic process GO:0046165 65 42 2,000 7,429E-06 5,855E-04 ! cytokinesis GO:0000910 84 42 2,000 7,429E-06 5,672E-04 ! negative regulation of protein ubiquitination GO:0031397 10 5 1,000 7,839E-06 5,803E-04 ! polyol metabolic process GO:0019751 77 45 2,000 9,166E-06 6,586E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 9,8E-06 6,84E-04 ! neural tube development GO:0021915 91 47 2,000 1,046E-05 7,099E-04 ! activation of Ras GTPase activity GO:0032856 13 6 1,000 1,175E-05 7,759E-04 GO:0032862|activation of Rho GTPase activity, ! regulation of protein complex disassembly GO:0043244 127 52 2,000 1,421E-05 9,139E-04 ! morphogenesis of embryonic epithelium GO:0016331 106 52 2,000 1,421E-05 8,904E-04 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 1,593E-05 9,732E-04 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 2,000 1,684E-05 1,004E-03 ! regulation of actin filament length GO:0030832 118 58 2,000 1,977E-05 1,15E-03 ! positive regulation of organelle organization GO:0010638 108 58 2,000 1,977E-05 1,123E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,191E-05 1,217E-03 ! regulation of focal adhesion formation GO:0051893 23 8 1,000 2,191E-05 1,19E-03 ! regulation of cellular component size GO:0032535 125 61 2,000 2,302E-05 1,223E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 2,816E-05 1,464E-03 ! cell projection assembly GO:0030031 138 68 2,000 3,192E-05 1,625E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 3,335E-05 1,663E-03 ! negative regulation of kinase activity GO:0033673 145 70 2,000 3,482E-05 1,701E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 3,518E-05 1,685E-03 ! regulation of stress fiber formation GO:0051492 34 10 1,000 3,518E-05 1,653E-03 ! actin filament organization GO:0007015 167 72 2,000 3,789E-05 1,747E-03 ! negative regulation of transferase activity GO:0051348 155 74 2,000 4,114E-05 1,861E-03 ! axon guidance GO:0007411 162 75 2,000 4,283E-05 1,902E-03 ! regulation of actin filament bundle formation GO:0032231 37 11 1,000 4,297E-05 1,875E-03 ! keratinocyte proliferation GO:0043616 19 11 1,000 4,297E-05 1,842E-03 ! positive regulation of Rho GTPase activity GO:0032321 31 11 1,000 4,297E-05 1,81E-03 ! positive regulation of cell growth GO:0030307 24 13 1,000 6,087E-05 2,52E-03 ! negative regulation of caspase activity GO:0043154 23 14 1,000 7,097E-05 2,89E-03 ! positive regulation of Ras GTPase activity GO:0032320 42 14 1,000 7,097E-05 2,842E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 7,097E-05 2,797E-03 ! tube morphogenesis GO:0035239 194 89 2,000 7,141E-05 2,769E-03 ! response to unfolded protein GO:0006986 139 90 2,000 7,383E-05 2,818E-03 ! positive regulation of GTPase activity GO:0043547 43 15 1,000 8,185E-05 3,076E-03 ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 8,403E-05 3,11E-03 ! response to protein stimulus GO:0051789 158 96 2,000 8,946E-05 3,262E-03 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 9,349E-05 3,359E-03 ! positive regulation of cell size GO:0045793 29 16 1,000 9,349E-05 3,31E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 9,349E-05 3,263E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 9,512E-05 3,273E-03 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 1,059E-04 3,593E-03 ! skin development GO:0043588 42 20 1,000 1,477E-04 4,943E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 1,477E-04 4,876E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 1,477E-04 4,811E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of translation GO:0017148 32 20 1,000 1,477E-04 4,747E-03 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 1,963E-04 6,229E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of Rho GTPase activity GO:0032319 56 23 1,000 1,963E-04 6,149E-03 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 2,141E-04 6,619E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 2,325E-04 7,101E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 2,518E-04 7,594E-03 ! negative regulation of protein modification process GO:0031400 66 28 1,000 2,925E-04 8,714E-03 ! fat cell differentiation GO:0045444 57 28 1,000 2,925E-04 8,609E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 3,14E-04 9,132E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 4,327E-04 0,0124349 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 4,853E-04 0,01378644 ! RNA export from nucleus GO:0006405 61 41 1,000 6,299E-04 0,01768824 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 7,588E-04 0,02106526 ! keratinocyte differentiation GO:0030216 81 45 1,000 7,588E-04 0,02082857 ! response to insulin stimulus GO:0032868 98 47 1,000 8,276E-04 0,02246516 ! positive regulation of cell cycle GO:0045787 96 48 1,000 8,631E-04 0,02317129 ! response to calcium ion GO:0051592 94 49 1,000 8,993E-04 0,02388131 ! epidermal cell differentiation GO:0009913 87 50 1,000 9,363E-04 0,02459506 ! positive regulation of growth GO:0045927 96 53 1,000 1,051E-03 0,02732653 ! response to UV GO:0009411 120 55 1,000 1,132E-03 0,02910572 ! nuclear export GO:0051168 110 59 1,000 1,301E-03 0,03311152 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 1,436E-03 0,0361567 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 1,529E-03 0,03811062 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 1,724E-03 0,04253294 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 1,774E-03 0,04334023 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 1,93E-03 0,04667366 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 1,93E-03 0,04621607 ! regulation of caspase activity GO:0043281 136 74 1,000 2,037E-03 0,0483095 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 2,037E-03 0,04784498 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 2,203E-03 0,05125067 ! positive regulation of ligase activity GO:0051351 130 77 1,000 2,203E-03 0,05076717 ! blood coagulation GO:0007596 151 79 1,000 2,317E-03 0,05289752 GO:0050817|coagulation, ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 2,317E-03 0,05240773 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 2,434E-03 0,0545455 ! regulation of peptidase activity GO:0052547 150 82 1,000 2,493E-03 0,05536982 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 2,553E-03 0,05619432 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 2,614E-03 0,05701896 ! regulation of ligase activity GO:0051340 147 84 1,000 2,614E-03 0,05651437 ! hemostasis GO:0007599 165 85 1,000 2,676E-03 0,05733633 ! mitochondrion organization GO:0007005 159 87 1,000 2,801E-03 0,0594935 ! cellular respiration GO:0045333 143 88 1,000 2,864E-03 0,06031845 ! response to inorganic substance GO:0010035 173 90 1,000 2,993E-03 0,062498 ! positive regulation of protein modification process GO:0031401 156 90 1,000 2,993E-03 0,06196835 ! regulation of cell adhesion GO:0030155 241 92 1,000 3,125E-03 0,0641527 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 3,192E-03 0,06497987 GO:0010498|proteasomal protein catabolic process, ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 4,494E-03 0,09072651 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 4,494E-03 0,08998285 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,494E-03 0,08925128 ! positive regulation of helicase activity GO:0051096 12 5 0,000 4,494E-03 0,08853151 ! neuron fate determination GO:0048664 7 5 0,000 4,494E-03 0,08782326 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,494E-03 0,08712625 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 4,494E-03 0,08644022 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 4,494E-03 0,0857649 ! polyol transport GO:0015791 12 5 0,000 4,494E-03 0,08510006 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,494E-03 0,08444544 ! response to superoxide GO:0000303 10 5 0,000 4,494E-03 0,08380082 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,494E-03 0,08316596 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 4,494E-03 0,08254066 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 4,494E-03 0,08192468 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,494E-03 0,08131783 ! female meiosis GO:0007143 10 5 0,000 4,494E-03 0,08071991 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 4,494E-03 0,08013071 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,494E-03 0,07955005 ! hypothalamus development GO:0021854 9 5 0,000 4,494E-03 0,07897775 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 4,494E-03 0,07841362 ! cobalt ion transport GO:0006824 11 5 0,000 4,494E-03 0,0778575 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 4,494E-03 0,07730921 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 4,494E-03 0,07676858 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,494E-03 0,07623547 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,494E-03 0,07570971 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 4,494E-03 0,07519115 ! embryonic camera-type eye development GO:0031076 12 5 0,000 4,494E-03 0,07467964 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,494E-03 0,07417505 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,494E-03 0,07367723 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 4,494E-03 0,07318605 ! transposition GO:0032196 9 5 0,000 4,494E-03 0,07270137 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 4,494E-03 0,07222307 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 4,494E-03 0,07175103 ! negative chemotaxis GO:0050919 16 5 0,000 4,494E-03 0,07128511 ! positive regulation of histone modification GO:0031058 6 5 0,000 4,494E-03 0,07082521 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,494E-03 0,0703712 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 4,494E-03 0,06992298 ! behavioral response to pain GO:0048266 10 5 0,000 4,494E-03 0,06948043 ! clathrin coat assembly GO:0048268 15 5 0,000 4,494E-03 0,06904344 ! Notch receptor processing GO:0007220 11 5 0,000 4,494E-03 0,06861192 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,494E-03 0,06818576 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 4,494E-03 0,06776486 ! micturition GO:0060073 9 5 0,000 4,494E-03 0,06734912 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,494E-03 0,06693846 ! copulation GO:0007620 9 5 0,000 4,494E-03 0,06653277 ! glial cell fate commitment GO:0021781 14 5 0,000 4,494E-03 0,06613197 ! protein maturation by protein folding GO:0022417 14 5 0,000 4,494E-03 0,06573597 ! bioluminescence GO:0008218 9 5 0,000 4,494E-03 0,06534469 ! spermidine metabolic process GO:0008216 7 5 0,000 4,494E-03 0,06495803 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,494E-03 0,06457593 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,494E-03 0,06419829 ! apoptotic cell clearance GO:0043277 23 5 0,000 4,494E-03 0,06382504 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,494E-03 0,06345611 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 4,494E-03 0,06309142 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,494E-03 0,0627309 ! grooming behavior GO:0007625 6 5 0,000 4,494E-03 0,06237447 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 4,494E-03 0,06202208 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,494E-03 0,06167364 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 4,494E-03 0,06132909 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,494E-03 0,06098837 ! response to protozoan GO:0001562 13 5 0,000 4,494E-03 0,06065142 ! positive regulation of glycolysis GO:0045821 13 5 0,000 4,494E-03 0,06031817 ! lymph vessel development GO:0001945 10 5 0,000 4,494E-03 0,05998856 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 4,494E-03 0,05966254 ! endochondral ossification GO:0001958 17 5 0,000 4,494E-03 0,05934004 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,494E-03 0,05902101 ! single strand break repair GO:0000012 8 5 0,000 4,494E-03 0,05870539 ! parathyroid gland development GO:0060017 14 5 0,000 4,494E-03 0,05839312 ! anagen GO:0042640 7 5 0,000 4,494E-03 0,05808417 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,494E-03 0,05777846 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,494E-03 0,05747595 ! cytokine secretion GO:0050663 15 5 0,000 4,494E-03 0,0571766 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 4,494E-03 0,05688035 ! ceramide catabolic process GO:0046514 7 5 0,000 4,494E-03 0,05658715 ! skeletal myofibril assembly GO:0014866 12 5 0,000 4,494E-03 0,05629696 ! smooth muscle tissue development GO:0048745 32 5 0,000 4,494E-03 0,05600973 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,494E-03 0,05572542 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,494E-03 0,05544398 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,494E-03 0,05516536 ! cardiac muscle fiber development GO:0048739 12 5 0,000 4,494E-03 0,05488954 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,494E-03 0,05461645 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 4,494E-03 0,05434608 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,494E-03 0,05407836 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 4,494E-03 0,05381327 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,494E-03 0,05355077 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 4,494E-03 0,05329081 ! glycine biosynthetic process GO:0006545 7 5 0,000 4,494E-03 0,05303337 ! microvillus organization GO:0032528 8 5 0,000 4,494E-03 0,0527784 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 4,494E-03 0,05252587 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 4,494E-03 0,05227575 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 4,494E-03 0,052028 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 4,494E-03 0,05178258 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 4,494E-03 0,05153947 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 4,494E-03 0,05129863 ! polyol biosynthetic process GO:0046173 6 5 0,000 4,494E-03 0,05106003 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 4,494E-03 0,05082364 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 4,494E-03 0,05058943 ! muscle cell migration GO:0014812 8 5 0,000 4,494E-03 0,05035737 ! mitochondrial fission GO:0000266 8 5 0,000 4,494E-03 0,05012743 ! sister chromatid cohesion GO:0007062 15 5 0,000 4,494E-03 0,04989958 ! response to tumor necrosis factor GO:0034612 10 5 0,000 4,494E-03 0,04967379 ! mRNA transcription GO:0009299 10 5 0,000 4,494E-03 0,04945003 ! nerve growth factor processing GO:0032455 9 5 0,000 4,494E-03 0,04922828 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 4,494E-03 0,04900851 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 4,494E-03 0,0487907 ! anaerobic glycolysis GO:0019642 6 5 0,000 4,494E-03 0,04857481 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,494E-03 0,04836083 ! monocyte activation GO:0042117 10 5 0,000 4,494E-03 0,04814872 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,494E-03 0,04793846 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,494E-03 0,04773003 ! response to food GO:0032094 6 5 0,000 4,494E-03 0,04752341 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,494E-03 0,04731857 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,494E-03 0,04711548 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 4,494E-03 0,04691413 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,494E-03 0,0467145 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 4,494E-03 0,04651656 ! forebrain neuron development GO:0021884 13 5 0,000 4,494E-03 0,04632028 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,494E-03 0,04612566 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 4,494E-03 0,04593267 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 4,494E-03 0,04574128 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,494E-03 0,04555148 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 4,494E-03 0,04536325 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,494E-03 0,04517657 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 4,494E-03 0,04499142 ! lipid glycosylation GO:0030259 7 5 0,000 4,494E-03 0,04480778 ! nucleobase transport GO:0015851 6 5 0,000 4,494E-03 0,04462564 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,494E-03 0,04444497 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 4,494E-03 0,04426576 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 4,494E-03 0,04408798 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 4,494E-03 0,04391163 ! basic amino acid transport GO:0015802 12 5 0,000 4,494E-03 0,04373668 ! cellular glucose homeostasis GO:0001678 6 5 0,000 4,494E-03 0,04356312 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 4,494E-03 0,04339094 ! actin nucleation GO:0045010 11 5 0,000 4,494E-03 0,04322011 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,494E-03 0,04305062 ! depurination GO:0045007 5 5 0,000 4,494E-03 0,04288245 ! depyrimidination GO:0045008 10 5 0,000 4,494E-03 0,04271559 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,494E-03 0,04255003 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,494E-03 0,04238574 ! G2/M transition checkpoint GO:0031576 8 5 0,000 4,494E-03 0,04222272 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,494E-03 0,04206095 ! zinc ion homeostasis GO:0055069 9 5 0,000 4,494E-03 0,04190041 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 4,494E-03 0,04174109 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 4,494E-03 0,04158298 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,494E-03 0,04142607 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,494E-03 0,04127033 ! activated T cell proliferation GO:0050798 16 5 0,000 4,494E-03 0,04111576 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,494E-03 0,04096234 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 4,494E-03 0,04081006 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,494E-03 0,04065892 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,494E-03 0,04050888 ! gamma-delta T cell activation GO:0046629 6 5 0,000 4,494E-03 0,04035995 ! response to arsenic GO:0046685 11 5 0,000 4,494E-03 0,04021211 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 4,494E-03 0,04006536 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,494E-03 0,03991966 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 4,494E-03 0,03977503 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 4,494E-03 0,03963143 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 4,494E-03 0,03948888 ! response to mercury ion GO:0046689 8 5 0,000 4,494E-03 0,03934734 ! response to cadmium ion GO:0046686 7 5 0,000 4,494E-03 0,03920681 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 4,494E-03 0,03906729 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 4,494E-03 0,03892875 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 4,494E-03 0,03879119 ! bile acid biosynthetic process GO:0006699 7 5 0,000 4,494E-03 0,0386546 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 4,494E-03 0,03851897 ! ganglioside catabolic process GO:0006689 12 5 0,000 4,494E-03 0,03838429 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,494E-03 0,03825055 ! decidualization GO:0046697 11 5 0,000 4,494E-03 0,03811773 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 4,494E-03 0,03798584 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 4,494E-03 0,03785485 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 4,494E-03 0,03772477 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 4,494E-03 0,03759557 ! embryonic cleavage GO:0040016 6 5 0,000 4,494E-03 0,03746726 ! peroxisome fission GO:0016559 5 5 0,000 4,494E-03 0,03733982 ! histone demethylation GO:0016577 13 5 0,000 4,494E-03 0,03721325 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 4,494E-03 0,03708752 ! mitotic recombination GO:0006312 9 5 0,000 4,494E-03 0,03696265 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 4,494E-03 0,03683862 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,494E-03 0,03671541 ! metaphase plate congression GO:0051310 7 5 0,000 4,494E-03 0,03659302 ! regulation of sterol transport GO:0032371 7 5 0,000 4,494E-03 0,03647145 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,494E-03 0,03635069 ! enteric nervous system development GO:0048484 8 5 0,000 4,494E-03 0,03623072 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 4,494E-03 0,03611154 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 4,494E-03 0,03599314 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 4,494E-03 0,03587551 ! muscle cell proliferation GO:0033002 12 5 0,000 4,494E-03 0,03575866 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,494E-03 0,03564256 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 4,494E-03 0,03552721 ! B cell homeostasis GO:0001782 13 5 0,000 4,494E-03 0,0354126 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 4,494E-03 0,03529874 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,494E-03 0,0351856 ! metaphase GO:0051323 11 5 0,000 4,494E-03 0,03507319 ! melatonin biosynthetic process GO:0030187 7 5 0,000 4,494E-03 0,03496149 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 4,494E-03 0,0348505 ! cellular response to nutrient GO:0031670 8 5 0,000 4,494E-03 0,03474021 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,494E-03 0,03463062 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 4,494E-03 0,03452172 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 4,494E-03 0,0344135 ! regulation of hair follicle development GO:0051797 10 5 0,000 4,494E-03 0,03430596 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 4,494E-03 0,03419909 ! response to redox state GO:0051775 6 5 0,000 4,494E-03 0,03409288 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 4,494E-03 0,03398733 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 4,494E-03 0,03388243 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,494E-03 0,03377818 ! brown fat cell differentiation GO:0050873 7 5 0,000 4,494E-03 0,03367456 ! regulation of telomerase activity GO:0051972 7 5 0,000 4,494E-03 0,03357158 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,494E-03 0,03346923 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 4,494E-03 0,0333675 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,494E-03 0,03326639 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 4,494E-03 0,03316588 ! striatum development GO:0021756 14 5 0,000 4,494E-03 0,03306599 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 4,494E-03 0,03296669 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,494E-03 0,03286799 ! glial cell migration GO:0008347 10 5 0,000 4,494E-03 0,03276987 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,494E-03 0,03267234 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 4,494E-03 0,03257539 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,494E-03 0,03247902 ! T cell activation during immune response GO:0002286 9 5 0,000 4,494E-03 0,03238321 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,494E-03 0,03228796 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,494E-03 0,03219328 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 4,494E-03 0,03209914 ! neuroprotection GO:0043526 8 5 0,000 4,494E-03 0,03200556 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,494E-03 0,03191252 ! regulation of sensory perception GO:0051931 8 5 0,000 4,494E-03 0,03182002 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,494E-03 0,03172806 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,494E-03 0,03163662 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 4,494E-03 0,03154571 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 4,494E-03 0,03145532 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,494E-03 0,03136545 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 4,494E-03 0,03127609 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,494E-03 0,03118724 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 4,494E-03 0,03109889 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 4,494E-03 0,03101104 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 4,494E-03 0,03092368 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,494E-03 0,03083682 ! spindle assembly GO:0051225 6 5 0,000 4,494E-03 0,03075044 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,494E-03 0,03066455 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,494E-03 0,03057913 ! protein palmitoylation GO:0018345 12 5 0,000 4,494E-03 0,03049419 ! drug metabolic process GO:0017144 7 5 0,000 4,494E-03 0,03040972 ! stem cell division GO:0017145 11 5 0,000 4,494E-03 0,03032571 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,494E-03 0,03024217 ! organ regeneration GO:0031100 7 5 0,000 4,494E-03 0,03015909 ! carnitine metabolic process GO:0009437 8 5 0,000 4,494E-03 0,03007646 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,494E-03 0,02999428 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 5,39E-03 0,03587942 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,39E-03 0,03578192 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 5,39E-03 0,03568495 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 5,39E-03 0,0355885 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 5,39E-03 0,03549258 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 5,39E-03 0,03539717 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 5,39E-03 0,03530227 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 5,39E-03 0,03520788 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 5,39E-03 0,03511399 ! response to oxygen radical GO:0000305 11 6 0,000 5,39E-03 0,0350206 ! positive regulation of axon extension GO:0045773 13 6 0,000 5,39E-03 0,03492771 ! myoblast cell fate commitment GO:0048625 18 6 0,000 5,39E-03 0,03483531 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 5,39E-03 0,0347434 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 5,39E-03 0,03465197 ! regulation of interferon-beta production GO:0032648 8 6 0,000 5,39E-03 0,03456102 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 5,39E-03 0,03447054 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 5,39E-03 0,03438054 ! forebrain regionalization GO:0021871 9 6 0,000 5,39E-03 0,03429101 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 5,39E-03 0,03420194 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 5,39E-03 0,03411333 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 5,39E-03 0,03402519 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 5,39E-03 0,03393749 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 5,39E-03 0,03385025 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 5,39E-03 0,03376345 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 5,39E-03 0,0336771 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 5,39E-03 0,03359119 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 5,39E-03 0,03350572 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 5,39E-03 0,03342068 ! malate metabolic process GO:0006108 13 6 0,000 5,39E-03 0,03333607 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 5,39E-03 0,03325189 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 5,39E-03 0,03316813 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 5,39E-03 0,03308479 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 5,39E-03 0,03300187 ! protein refolding GO:0042026 15 6 0,000 5,39E-03 0,03291937 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 5,39E-03 0,03283727 ! opsonization GO:0008228 8 6 0,000 5,39E-03 0,03275559 ! mating behavior GO:0007617 7 6 0,000 5,39E-03 0,03267431 ! erythrocyte maturation GO:0043249 8 6 0,000 5,39E-03 0,03259343 ! embryonic hemopoiesis GO:0035162 16 6 0,000 5,39E-03 0,03251296 ! protein amino acid dealkylation GO:0008214 15 6 0,000 5,39E-03 0,03243287 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 5,39E-03 0,03235319 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 5,39E-03 0,03227389 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 5,39E-03 0,03219498 ! response to interferon-gamma GO:0034341 16 6 0,000 5,39E-03 0,03211646 ! toxin metabolic process GO:0009404 11 6 0,000 5,39E-03 0,03203831 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 5,39E-03 0,03196055 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 5,39E-03 0,03188316 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 5,39E-03 0,03180615 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 5,39E-03 0,03172951 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 5,39E-03 0,03165324 ! cGMP-mediated signaling GO:0019934 14 6 0,000 5,39E-03 0,03157733 ! dorsal spinal cord development GO:0021516 10 6 0,000 5,39E-03 0,03150179 ! activation of MAPKKK activity GO:0000185 12 6 0,000 5,39E-03 0,0314266 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 5,39E-03 0,03135178 ! thymic T cell selection GO:0045061 16 6 0,000 5,39E-03 0,03127731 ! sphingoid catabolic process GO:0046521 8 6 0,000 5,39E-03 0,03120319 ! protein lipoylation GO:0009249 10 6 0,000 5,39E-03 0,03112943 ! transepithelial chloride transport GO:0030321 12 6 0,000 5,39E-03 0,03105601 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 5,39E-03 0,03098293 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 5,39E-03 0,0309102 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 5,39E-03 0,03083781 ! glutamate catabolic process GO:0006538 12 6 0,000 5,39E-03 0,03076576 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 5,39E-03 0,03069405 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 5,39E-03 0,03062267 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 5,39E-03 0,03055162 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 5,39E-03 0,0304809 ! hyperosmotic response GO:0006972 10 6 0,000 5,39E-03 0,0304105 ! L-serine biosynthetic process GO:0006564 7 6 0,000 5,39E-03 0,03034043 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 5,39E-03 0,03027068 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 5,39E-03 0,03020125 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 5,39E-03 0,03013214 ! urea metabolic process GO:0019627 7 6 0,000 5,39E-03 0,03006335 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 5,39E-03 0,02999487 ! neutrophil activation GO:0042119 7 6 0,000 5,39E-03 0,0299267 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 5,39E-03 0,02985884 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 5,39E-03 0,02979128 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 5,39E-03 0,02972403 ! paraxial mesoderm development GO:0048339 16 6 0,000 5,39E-03 0,02965709 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 5,39E-03 0,02959044 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 5,39E-03 0,0295241 ! neuron apoptosis GO:0051402 15 6 0,000 5,39E-03 0,02945805 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 5,39E-03 0,02939229 ! T cell mediated immunity GO:0002456 17 6 0,000 5,39E-03 0,02932683 ! negative regulation of platelet activation GO:0010544 9 6 0,000 5,39E-03 0,02926166 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 5,39E-03 0,02919678 ! carnitine transport GO:0015879 10 6 0,000 5,39E-03 0,02913218 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,39E-03 0,02906787 ! positive regulation of exocytosis GO:0045921 11 6 0,000 5,39E-03 0,02900385 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 5,39E-03 0,0289401 ! early endosome to late endosome transport GO:0045022 16 6 0,000 5,39E-03 0,02887664 ! 5S class rRNA transcription GO:0042791 13 6 0,000 5,39E-03 0,02881345 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 5,39E-03 0,02875054 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 5,39E-03 0,0286879 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 5,39E-03 0,02862554 ! sodium ion homeostasis GO:0055078 12 6 0,000 5,39E-03 0,02856344 ! establishment of spindle localization GO:0051293 16 6 0,000 5,39E-03 0,02850162 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 5,39E-03 0,02844006 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 5,39E-03 0,02837876 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 5,39E-03 0,02831774 ! response to UV-C GO:0010225 14 6 0,000 5,39E-03 0,02825697 ! astrocyte development GO:0014002 16 6 0,000 5,39E-03 0,02819646 ! protein targeting to lysosome GO:0006622 12 6 0,000 5,39E-03 0,02813621 ! purine base biosynthetic process GO:0009113 17 6 0,000 5,39E-03 0,02807622 ! interaction with symbiont GO:0051702 14 6 0,000 5,39E-03 0,02801648 ! regulation of dendrite development GO:0050773 16 6 0,000 5,39E-03 0,027957 ! peptidyl-arginine modification GO:0018195 13 6 0,000 5,39E-03 0,02789777 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 5,39E-03 0,02783879 ! response to copper ion GO:0046688 10 6 0,000 5,39E-03 0,02778006 ! response to exogenous dsRNA GO:0043330 13 6 0,000 5,39E-03 0,02772157 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 5,39E-03 0,02766333 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,39E-03 0,02760534 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 5,39E-03 0,02754759 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 5,39E-03 0,02749008 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 5,39E-03 0,02743281 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,39E-03 0,02737577 ! nucleoside catabolic process GO:0009164 10 6 0,000 5,39E-03 0,02731898 ! hair follicle maturation GO:0048820 8 6 0,000 5,39E-03 0,02726242 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 5,39E-03 0,02720609 ! Schwann cell development GO:0014044 15 6 0,000 5,39E-03 0,02714999 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 5,39E-03 0,02709413 ! response to pheromone GO:0019236 6 6 0,000 5,39E-03 0,02703849 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 5,39E-03 0,02698309 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 5,39E-03 0,02692791 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 5,39E-03 0,02687295 ! base conversion or substitution editing GO:0016553 6 6 0,000 5,39E-03 0,02681822 ! subpallium development GO:0021544 15 6 0,000 5,39E-03 0,02676371 ! neural tube patterning GO:0021532 8 6 0,000 5,39E-03 0,02670943 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 5,39E-03 0,02665536 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 5,39E-03 0,02660151 ! maintenance of organ identity GO:0048496 9 6 0,000 5,39E-03 0,02654788 ! G2 phase GO:0051319 16 6 0,000 5,39E-03 0,02649446 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 5,39E-03 0,02644126 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 5,39E-03 0,02638827 ! oxygen homeostasis GO:0032364 10 6 0,000 5,39E-03 0,02633549 ! establishment of planar polarity GO:0001736 7 6 0,000 5,39E-03 0,02628293 ! regulation of mast cell activation GO:0033003 13 6 0,000 5,39E-03 0,02623057 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 5,39E-03 0,02617842 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 5,39E-03 0,02612648 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 5,39E-03 0,02607475 ! receptor internalization GO:0031623 11 6 0,000 5,39E-03 0,02602322 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 5,39E-03 0,02597189 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 5,39E-03 0,02592076 ! neutrophil homeostasis GO:0001780 11 6 0,000 5,39E-03 0,02586984 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,39E-03 0,02581911 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 5,39E-03 0,02576858 ! protein deubiquitination GO:0016579 16 6 0,000 5,39E-03 0,02571826 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 5,39E-03 0,02566812 ! protein destabilization GO:0031648 9 6 0,000 5,39E-03 0,02561818 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 5,39E-03 0,02556844 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 5,39E-03 0,02551889 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 5,39E-03 0,02546953 ! regulation of viral transcription GO:0046782 11 6 0,000 5,39E-03 0,02542036 ! progesterone metabolic process GO:0042448 12 6 0,000 5,39E-03 0,02537138 ! negative regulation of axon extension GO:0030517 24 6 0,000 5,39E-03 0,02532259 ! removal of superoxide radicals GO:0019430 12 6 0,000 5,39E-03 0,02527399 ! triglyceride catabolic process GO:0019433 10 6 0,000 5,39E-03 0,02522557 ! determination of adult lifespan GO:0008340 17 6 0,000 5,39E-03 0,02517734 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 5,39E-03 0,02512929 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 5,39E-03 0,02508142 ! catecholamine transport GO:0051937 9 6 0,000 5,39E-03 0,02503374 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 5,39E-03 0,02498624 ! sensory cilium assembly GO:0035058 10 6 0,000 5,39E-03 0,02493891 ! organ or tissue specific immune response GO:0002251 8 6 0,000 5,39E-03 0,02489177 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 5,39E-03 0,02484481 ! maternal placenta development GO:0001893 12 6 0,000 5,39E-03 0,02479802 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 5,39E-03 0,0247514 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 5,39E-03 0,02470497 ! negative regulation of B cell activation GO:0050869 14 6 0,000 5,39E-03 0,0246587 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 5,39E-03 0,02461261 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 5,39E-03 0,02456669 ! positive regulation of coagulation GO:0050820 13 6 0,000 5,39E-03 0,02452094 ! cellular anion homeostasis GO:0030002 11 6 0,000 5,39E-03 0,02447537 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 6,286E-03 0,0284892 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 6,286E-03 0,02843644 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 6,286E-03 0,02838387 ! behavioral response to cocaine GO:0048148 14 7 0,000 6,286E-03 0,02833151 ! regulation of helicase activity GO:0051095 16 7 0,000 6,286E-03 0,02827933 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 6,286E-03 0,02822735 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 6,286E-03 0,02817555 ! sleep GO:0030431 16 7 0,000 6,286E-03 0,02812395 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 6,286E-03 0,02807253 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 6,286E-03 0,02802131 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 6,286E-03 0,02797027 ! prostate gland development GO:0030850 14 7 0,000 6,286E-03 0,02791941 ! nucleotide-sugar transport GO:0015780 11 7 0,000 6,286E-03 0,02786874 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,286E-03 0,02781825 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 6,286E-03 0,02776795 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 6,286E-03 0,02771783 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,286E-03 0,02766788 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 6,286E-03 0,02761812 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 6,286E-03 0,02756854 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 6,286E-03 0,02751913 ! SMAD protein complex assembly GO:0007183 13 7 0,000 6,286E-03 0,0274699 ! glycolipid transport GO:0046836 11 7 0,000 6,286E-03 0,02742085 ! protein amino acid sulfation GO:0006477 10 7 0,000 6,286E-03 0,02737197 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 6,286E-03 0,02732327 ! neuron adhesion GO:0007158 14 7 0,000 6,286E-03 0,02727474 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 6,286E-03 0,02722638 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 6,286E-03 0,02717819 ! establishment of tissue polarity GO:0007164 8 7 0,000 6,286E-03 0,02713017 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 6,286E-03 0,02708232 ! mRNA stabilization GO:0048255 18 7 0,000 6,286E-03 0,02703464 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 6,286E-03 0,02698713 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 6,286E-03 0,02693978 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 6,286E-03 0,0268926 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 6,286E-03 0,02684559 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 6,286E-03 0,02679874 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 6,286E-03 0,02675205 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 6,286E-03 0,02670552 ! lipoprotein transport GO:0042953 14 7 0,000 6,286E-03 0,02665916 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 6,286E-03 0,02661296 ! rhythmic behavior GO:0007622 17 7 0,000 6,286E-03 0,02656691 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 6,286E-03 0,02652103 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 6,286E-03 0,0264753 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 6,286E-03 0,02642974 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 6,286E-03 0,02638432 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 6,286E-03 0,02633907 ! regulation of odontogenesis GO:0042481 14 7 0,000 6,286E-03 0,02629397 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 6,286E-03 0,02624902 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 6,286E-03 0,02620423 ! mechanosensory behavior GO:0007638 16 7 0,000 6,286E-03 0,02615958 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 6,286E-03 0,0261151 ! positive regulation of isotype switching GO:0045830 17 7 0,000 6,286E-03 0,02607076 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 6,286E-03 0,02602657 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 6,286E-03 0,02598253 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,286E-03 0,02593864 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,286E-03 0,0258949 ! spinal cord patterning GO:0021511 14 7 0,000 6,286E-03 0,02585131 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 6,286E-03 0,02580786 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 6,286E-03 0,02576456 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 6,286E-03 0,0257214 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 6,286E-03 0,02567839 ! adrenal gland development GO:0030325 17 7 0,000 6,286E-03 0,02563552 ! cysteine metabolic process GO:0006534 13 7 0,000 6,286E-03 0,02559279 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 6,286E-03 0,02555021 ! ovulation GO:0030728 10 7 0,000 6,286E-03 0,02550777 ! adenohypophysis development GO:0021984 11 7 0,000 6,286E-03 0,02546547 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 6,286E-03 0,0254233 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 6,286E-03 0,02538128 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 6,286E-03 0,0253394 ! microtubule nucleation GO:0007020 21 7 0,000 6,286E-03 0,02529765 ! proline biosynthetic process GO:0006561 10 7 0,000 6,286E-03 0,02525605 ! tryptophan metabolic process GO:0006568 11 7 0,000 6,286E-03 0,02521457 ! thyroid hormone generation GO:0006590 13 7 0,000 6,286E-03 0,02517324 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 6,286E-03 0,02513204 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 6,286E-03 0,02509097 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,286E-03 0,02505004 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 6,286E-03 0,02500924 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 6,286E-03 0,02496858 ! galactose metabolic process GO:0006012 13 7 0,000 6,286E-03 0,02492805 ! vesicle fusion GO:0006906 20 7 0,000 6,286E-03 0,02488764 ! response to dietary excess GO:0002021 8 7 0,000 6,286E-03 0,02484737 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 6,286E-03 0,02480723 ! intracellular pH reduction GO:0051452 13 7 0,000 6,286E-03 0,02476722 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 6,286E-03 0,02472734 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 6,286E-03 0,02468758 ! organ growth GO:0035265 15 7 0,000 6,286E-03 0,02464796 ! nucleoside transport GO:0015858 11 7 0,000 6,286E-03 0,02460846 ! nucleoside salvage GO:0043174 11 7 0,000 6,286E-03 0,02456908 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 6,286E-03 0,02452983 ! male sex determination GO:0030238 15 7 0,000 6,286E-03 0,02449071 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 6,286E-03 0,02445171 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 6,286E-03 0,02441284 ! parturition GO:0007567 16 7 0,000 6,286E-03 0,02437409 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 6,286E-03 0,02433546 ! rRNA modification GO:0000154 14 7 0,000 6,286E-03 0,02429696 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 6,286E-03 0,02425857 ! spindle checkpoint GO:0031577 16 7 0,000 6,286E-03 0,02422031 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 6,286E-03 0,02418217 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 6,286E-03 0,02414414 ! monocyte differentiation GO:0030224 16 7 0,000 6,286E-03 0,02410624 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 6,286E-03 0,02406846 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 6,286E-03 0,02403079 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 6,286E-03 0,02399324 ! hyaluronan metabolic process GO:0030212 9 7 0,000 6,286E-03 0,02395581 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 6,286E-03 0,0239185 ! anterograde axon cargo transport GO:0008089 18 7 0,000 6,286E-03 0,0238813 ! fibrinolysis GO:0042730 11 7 0,000 6,286E-03 0,02384422 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 6,286E-03 0,02380725 ! skeletal muscle contraction GO:0003009 8 7 0,000 6,286E-03 0,0237704 ! eating behavior GO:0042755 8 7 0,000 6,286E-03 0,02373366 ! B cell lineage commitment GO:0002326 21 7 0,000 6,286E-03 0,02369703 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 6,286E-03 0,02366052 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 6,286E-03 0,02362412 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 6,286E-03 0,02358783 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 6,286E-03 0,02355165 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 6,286E-03 0,02351558 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 6,286E-03 0,02347963 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 6,286E-03 0,02344378 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 6,286E-03 0,02340804 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 6,286E-03 0,02337241 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 6,286E-03 0,02333689 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 6,286E-03 0,02330148 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 6,286E-03 0,02326618 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 6,286E-03 0,02323098 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 6,286E-03 0,02319589 ! histone ubiquitination GO:0016574 9 7 0,000 6,286E-03 0,0231609 ! regulation of meiosis GO:0040020 12 7 0,000 6,286E-03 0,02312602 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 6,286E-03 0,02309124 ! T cell lineage commitment GO:0002360 16 7 0,000 6,286E-03 0,02305657 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 6,286E-03 0,023022 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 6,286E-03 0,02298754 ! membrane to membrane docking GO:0022614 14 7 0,000 6,286E-03 0,02295318 ! transcription termination GO:0006353 14 7 0,000 6,286E-03 0,02291892 ! coenzyme A metabolic process GO:0015936 12 7 0,000 6,286E-03 0,02288476 ! anaphase GO:0051322 18 7 0,000 6,286E-03 0,02285071 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 6,286E-03 0,02281676 ! axonal fasciculation GO:0007413 19 7 0,000 6,286E-03 0,0227829 ! negative regulation of nuclear division GO:0051784 15 7 0,000 6,286E-03 0,02274915 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 6,286E-03 0,0227155 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 6,286E-03 0,02268194 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 6,286E-03 0,02264849 ! diuresis GO:0030146 12 7 0,000 6,286E-03 0,02261513 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 6,286E-03 0,02258188 ! thiamin metabolic process GO:0006772 7 7 0,000 6,286E-03 0,02254872 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,286E-03 0,02251565 ! antibiotic transport GO:0042891 9 7 0,000 6,286E-03 0,02248269 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,286E-03 0,02244982 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 6,286E-03 0,02241705 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 6,286E-03 0,02238437 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 6,286E-03 0,02235178 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 6,286E-03 0,0223193 ! melanin biosynthetic process GO:0042438 10 7 0,000 6,286E-03 0,0222869 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 6,286E-03 0,0222546 ! dopamine biosynthetic process GO:0042416 18 7 0,000 6,286E-03 0,0222224 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 6,286E-03 0,02219028 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 6,286E-03 0,02215826 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 6,286E-03 0,02212633 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 6,286E-03 0,0220945 ! endosome to lysosome transport GO:0008333 12 7 0,000 6,286E-03 0,02206275 ! protein modification by small protein removal GO:0070646 19 7 0,000 6,286E-03 0,0220311 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 6,286E-03 0,02199954 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 6,286E-03 0,02196806 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 6,286E-03 0,02193668 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 6,286E-03 0,02190539 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,286E-03 0,02187418 ! muscle adaptation GO:0043500 13 7 0,000 6,286E-03 0,02184307 ! embryonic heart tube development GO:0035050 14 7 0,000 6,286E-03 0,02181204 ! retina homeostasis GO:0001895 12 7 0,000 6,286E-03 0,0217811 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 6,286E-03 0,02175025 ! protein amino acid prenylation GO:0018346 19 7 0,000 6,286E-03 0,02171949 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 6,286E-03 0,02168881 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 6,286E-03 0,02165822 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 7,18E-03 0,02470662 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 7,18E-03 0,02467187 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 7,18E-03 0,02463721 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 7,18E-03 0,02460266 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 7,18E-03 0,0245682 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 7,18E-03 0,02453384 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 7,18E-03 0,02449958 ! male meiosis GO:0007140 9 8 0,000 7,18E-03 0,02446541 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 7,18E-03 0,02443133 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 7,18E-03 0,02439735 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 7,18E-03 0,02436347 ! meiotic prophase I GO:0007128 14 8 0,000 7,18E-03 0,02432968 ! response to zinc ion GO:0010043 12 8 0,000 7,18E-03 0,02429598 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 7,18E-03 0,02426237 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 7,18E-03 0,02422886 ! oligopeptide transport GO:0006857 16 8 0,000 7,18E-03 0,02419544 ! actin-myosin filament sliding GO:0033275 13 8 0,000 7,18E-03 0,02416212 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 7,18E-03 0,02412888 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 7,18E-03 0,02409574 ! signal peptide processing GO:0006465 12 8 0,000 7,18E-03 0,02406268 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 7,18E-03 0,02402972 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 7,18E-03 0,02399685 ! macrophage chemotaxis GO:0048246 12 8 0,000 7,18E-03 0,02396407 ! succinate metabolic process GO:0006105 17 8 0,000 7,18E-03 0,02393137 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 7,18E-03 0,02389877 ! membrane hyperpolarization GO:0060081 11 8 0,000 7,18E-03 0,02386625 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 7,18E-03 0,02383383 ! estrogen metabolic process GO:0008210 17 8 0,000 7,18E-03 0,02380149 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 7,18E-03 0,02376924 ! T-helper 1 type immune response GO:0042088 12 8 0,000 7,18E-03 0,02373707 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 7,18E-03 0,023705 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 7,18E-03 0,02367301 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 7,18E-03 0,0236411 ! reflex GO:0060004 17 8 0,000 7,18E-03 0,02360928 ! endothelial cell differentiation GO:0045446 17 8 0,000 7,18E-03 0,02357755 ! glycerolipid catabolic process GO:0046503 14 8 0,000 7,18E-03 0,0235459 ! hemoglobin metabolic process GO:0020027 14 8 0,000 7,18E-03 0,02351434 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 7,18E-03 0,02348286 ! pigment granule organization GO:0048753 17 8 0,000 7,18E-03 0,02345147 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 7,18E-03 0,02342016 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 7,18E-03 0,02338893 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 7,18E-03 0,02335779 ! astrocyte differentiation GO:0048708 19 8 0,000 7,18E-03 0,02332672 ! histidine catabolic process GO:0006548 10 8 0,000 7,18E-03 0,02329575 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 7,18E-03 0,02326485 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 7,18E-03 0,02323404 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 7,18E-03 0,0232033 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 7,18E-03 0,02317265 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 7,18E-03 0,02314208 ! regulation of pigmentation during development GO:0048070 25 8 0,000 7,18E-03 0,02311159 ! melanin metabolic process GO:0006582 17 8 0,000 7,18E-03 0,02308118 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 7,18E-03 0,02305085 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 7,18E-03 0,0230206 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 7,18E-03 0,02299043 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 7,18E-03 0,02296034 ! macrophage activation GO:0042116 13 8 0,000 7,18E-03 0,02293032 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 7,18E-03 0,02290039 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 7,18E-03 0,02287053 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 7,18E-03 0,02284075 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 7,18E-03 0,02281105 ! purine salvage GO:0043101 12 8 0,000 7,18E-03 0,02278142 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 7,18E-03 0,02275188 ! regulation of vascular permeability GO:0043114 12 8 0,000 7,18E-03 0,02272241 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 7,18E-03 0,02269301 ! osteoblast development GO:0002076 17 8 0,000 7,18E-03 0,02266369 ! positive regulation of vasodilation GO:0045909 14 8 0,000 7,18E-03 0,02263445 ! negative regulation of translational initiation GO:0045947 12 8 0,000 7,18E-03 0,02260528 ! Schwann cell differentiation GO:0014037 21 8 0,000 7,18E-03 0,02257619 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 7,18E-03 0,02254717 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 7,18E-03 0,02251822 ! response to UV-B GO:0010224 17 8 0,000 7,18E-03 0,02248935 ! protein targeting to vacuole GO:0006623 14 8 0,000 7,18E-03 0,02246056 ! protein retention in ER lumen GO:0006621 14 8 0,000 7,18E-03 0,02243184 ! intermediate filament organization GO:0045109 12 8 0,000 7,18E-03 0,02240319 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 7,18E-03 0,02237461 ! cellular extravasation GO:0045123 13 8 0,000 7,18E-03 0,02234611 ! cardiac muscle cell development GO:0055013 14 8 0,000 7,18E-03 0,02231768 ! response to antibiotic GO:0046677 11 8 0,000 7,18E-03 0,02228932 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 7,18E-03 0,02226104 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 7,18E-03 0,02223282 ! DNA topological change GO:0006265 12 8 0,000 7,18E-03 0,02220468 ! response to tropane GO:0014073 15 8 0,000 7,18E-03 0,02217661 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 7,18E-03 0,02214861 ! melanosome transport GO:0032402 13 8 0,000 7,18E-03 0,02212068 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 7,18E-03 0,02209282 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 7,18E-03 0,02206503 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 7,18E-03 0,02203731 ! mast cell activation GO:0045576 14 8 0,000 7,18E-03 0,02200966 ! multicellular organismal aging GO:0010259 20 8 0,000 7,18E-03 0,02198208 ! gas homeostasis GO:0033483 14 8 0,000 7,18E-03 0,02195456 ! dendrite morphogenesis GO:0048813 14 8 0,000 7,18E-03 0,02192712 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 7,18E-03 0,02189975 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 7,18E-03 0,02187244 ! nucleosome disassembly GO:0006337 14 8 0,000 7,18E-03 0,0218452 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 7,18E-03 0,02181803 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 7,18E-03 0,02179093 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 7,18E-03 0,02176389 ! establishment of chromosome localization GO:0051303 14 8 0,000 7,18E-03 0,02173692 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 7,18E-03 0,02171002 ! intracellular lipid transport GO:0032365 16 8 0,000 7,18E-03 0,02168319 ! response to tumor cell GO:0002347 16 8 0,000 7,18E-03 0,02165642 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 7,18E-03 0,02162971 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 7,18E-03 0,02160307 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 7,18E-03 0,0215765 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 7,18E-03 0,02155 ! positive regulation of epidermis development GO:0045684 13 8 0,000 7,18E-03 0,02152355 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 7,18E-03 0,02149718 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 7,18E-03 0,02147087 ! hormone catabolic process GO:0042447 17 8 0,000 7,18E-03 0,02144462 ! glycolipid catabolic process GO:0019377 16 8 0,000 7,18E-03 0,02141843 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 7,18E-03 0,02139231 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 7,18E-03 0,02136626 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 7,18E-03 0,02134026 ! positive regulation of glucose import GO:0046326 8 8 0,000 7,18E-03 0,02131433 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 7,18E-03 0,02128847 ! adult feeding behavior GO:0008343 10 8 0,000 7,18E-03 0,02126266 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 7,18E-03 0,02123692 ! ATP catabolic process GO:0006200 11 8 0,000 7,18E-03 0,02121124 ! blastocyst growth GO:0001832 19 8 0,000 7,18E-03 0,02118562 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 7,18E-03 0,02116007 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 7,18E-03 0,02113457 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 7,18E-03 0,02110914 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 7,18E-03 0,02108377 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 7,18E-03 0,02105846 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 7,18E-03 0,02103321 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 7,18E-03 0,02100802 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 7,18E-03 0,02098289 ! amino sugar catabolic process GO:0046348 11 8 0,000 7,18E-03 0,02095782 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 7,18E-03 0,02093281 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 7,18E-03 0,02090786 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 7,18E-03 0,02088297 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 7,18E-03 0,02085814 ! behavioral response to nicotine GO:0035095 12 8 0,000 7,18E-03 0,02083337 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 7,18E-03 0,02080866 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 7,18E-03 0,020784 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 7,18E-03 0,0207594 ! NAD biosynthetic process GO:0009435 17 8 0,000 7,18E-03 0,02073487 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 7,18E-03 0,02071039 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 7,18E-03 0,02068596 ! axon extension GO:0048675 16 9 0,000 8,074E-03 0,02323417 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 8,074E-03 0,02320684 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 8,074E-03 0,02317957 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 8,074E-03 0,02315236 ! pentose-phosphate shunt GO:0006098 16 9 0,000 8,074E-03 0,02312522 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 8,074E-03 0,02309814 ! cell proliferation in forebrain GO:0021846 18 9 0,000 8,074E-03 0,02307112 ! neutral lipid catabolic process GO:0046461 14 9 0,000 8,074E-03 0,02304417 ! reproductive behavior GO:0019098 22 9 0,000 8,074E-03 0,02301728 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 8,074E-03 0,02299046 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 8,074E-03 0,02296369 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 8,074E-03 0,02293699 ! UTP metabolic process GO:0046051 10 9 0,000 8,074E-03 0,02291035 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 8,074E-03 0,02288377 ! induction of positive chemotaxis GO:0050930 17 9 0,000 8,074E-03 0,02285725 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 8,074E-03 0,0228308 ! artery development GO:0060840 25 9 0,000 8,074E-03 0,02280441 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 8,074E-03 0,02277807 ! regulation of glycolysis GO:0006110 20 9 0,000 8,074E-03 0,0227518 ! cerebral cortex cell migration GO:0021795 18 9 0,000 8,074E-03 0,02272559 ! equilibrioception GO:0050957 20 9 0,000 8,074E-03 0,02269944 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 8,074E-03 0,02267335 ! chemosensory behavior GO:0007635 21 9 0,000 8,074E-03 0,02264731 ! microtubule bundle formation GO:0001578 22 9 0,000 8,074E-03 0,02262134 ! middle ear morphogenesis GO:0042474 14 9 0,000 8,074E-03 0,02259543 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 8,074E-03 0,02256958 ! leukocyte degranulation GO:0043299 16 9 0,000 8,074E-03 0,02254378 ! ganglioside metabolic process GO:0001573 22 9 0,000 8,074E-03 0,02251805 ! negative regulation of endocytosis GO:0045806 12 9 0,000 8,074E-03 0,02249237 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 8,074E-03 0,02246675 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 8,074E-03 0,0224412 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 8,074E-03 0,02241569 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 8,074E-03 0,02239025 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 8,074E-03 0,02236486 ! protein targeting to ER GO:0045047 25 9 0,000 8,074E-03 0,02233954 ! ceramide biosynthetic process GO:0046513 20 9 0,000 8,074E-03 0,02231427 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 8,074E-03 0,02228905 ! T cell selection GO:0045058 27 9 0,000 8,074E-03 0,02226389 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 8,074E-03 0,02223879 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 8,074E-03 0,02221375 ! glycine catabolic process GO:0006546 15 9 0,000 8,074E-03 0,02218876 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 8,074E-03 0,02216383 ! endosome organization GO:0007032 20 9 0,000 8,074E-03 0,02213896 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 8,074E-03 0,02211414 ! regulation of type I interferon production GO:0032479 12 9 0,000 8,074E-03 0,02208937 ! mannose metabolic process GO:0006013 13 9 0,000 8,074E-03 0,02206467 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 8,074E-03 0,02204001 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 8,074E-03 0,02201541 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 8,074E-03 0,02199087 ! Rac protein signal transduction GO:0016601 20 9 0,000 8,074E-03 0,02196638 ! receptor clustering GO:0043113 20 9 0,000 8,074E-03 0,02194195 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 8,074E-03 0,02191757 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 8,074E-03 0,02189324 ! retinol metabolic process GO:0042572 20 9 0,000 8,074E-03 0,02186897 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 8,074E-03 0,02184475 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 8,074E-03 0,02182059 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 8,074E-03 0,02179648 ! macrophage differentiation GO:0030225 15 9 0,000 8,074E-03 0,02177242 ! oligodendrocyte development GO:0014003 11 9 0,000 8,074E-03 0,02174841 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 8,074E-03 0,02172446 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 8,074E-03 0,02170056 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 8,074E-03 0,02167671 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 8,074E-03 0,02165292 ! response to amine stimulus GO:0014075 13 9 0,000 8,074E-03 0,02162918 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 8,074E-03 0,02160549 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 8,074E-03 0,02158185 ! erythrocyte development GO:0048821 17 9 0,000 8,074E-03 0,02155826 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 8,074E-03 0,02153473 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 8,074E-03 0,02151124 ! renal water homeostasis GO:0003091 15 9 0,000 8,074E-03 0,02148781 ! postreplication repair GO:0006301 25 9 0,000 8,074E-03 0,02146443 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 8,074E-03 0,0214411 ! icosanoid secretion GO:0032309 15 9 0,000 8,074E-03 0,02141782 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 8,074E-03 0,02139459 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 8,074E-03 0,02137141 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 8,074E-03 0,02134828 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 8,074E-03 0,0213252 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 8,074E-03 0,02130217 ! sterol catabolic process GO:0016127 14 9 0,000 8,074E-03 0,02127919 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 8,074E-03 0,02125626 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 8,074E-03 0,02123338 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 8,074E-03 0,02121055 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 8,074E-03 0,02118777 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 8,074E-03 0,02116503 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 8,074E-03 0,02114235 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 8,074E-03 0,02111971 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 8,074E-03 0,02109712 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 8,074E-03 0,02107458 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 8,074E-03 0,02105209 ! regulation of synaptogenesis GO:0051963 15 9 0,000 8,074E-03 0,02102965 ! purine base metabolic process GO:0006144 25 9 0,000 8,074E-03 0,02100725 ! pigment granule transport GO:0051904 17 9 0,000 8,074E-03 0,0209849 ! regulation of telomere maintenance GO:0032204 17 9 0,000 8,074E-03 0,0209626 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 8,074E-03 0,02094035 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 8,074E-03 0,02091814 ! regulation of muscle adaptation GO:0043502 14 9 0,000 8,074E-03 0,02089599 ! regulation of amino acid transport GO:0051955 12 9 0,000 8,074E-03 0,02087387 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 8,074E-03 0,02085181 ! mitochondrion localization GO:0051646 18 9 0,000 8,074E-03 0,02082979 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 8,968E-03 0,02310972 ! regulation of developmental growth GO:0048638 16 10 0,000 8,968E-03 0,02308537 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 8,968E-03 0,02306107 ! autophagic vacuole formation GO:0000045 17 10 0,000 8,968E-03 0,02303682 ! negative regulation of blood pressure GO:0045776 26 10 0,000 8,968E-03 0,02301262 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 8,968E-03 0,02298848 ! associative learning GO:0008306 21 10 0,000 8,968E-03 0,02296438 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 8,968E-03 0,02294033 ! phosphate transport GO:0006817 24 10 0,000 8,968E-03 0,02291634 ! cell volume homeostasis GO:0006884 17 10 0,000 8,968E-03 0,02289239 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 8,968E-03 0,0228685 ! CTP metabolic process GO:0046036 11 10 0,000 8,968E-03 0,02284465 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 8,968E-03 0,02282085 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 8,968E-03 0,02279711 ! GTP metabolic process GO:0046039 11 10 0,000 8,968E-03 0,02277341 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 8,968E-03 0,02274976 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 8,968E-03 0,02272616 ! social behavior GO:0035176 29 10 0,000 8,968E-03 0,02270261 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 8,968E-03 0,02267911 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 8,968E-03 0,02265566 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 8,968E-03 0,02263225 ! androgen metabolic process GO:0008209 17 10 0,000 8,968E-03 0,02260889 ! phospholipid efflux GO:0033700 19 10 0,000 8,968E-03 0,02258559 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 8,968E-03 0,02256233 ! bile acid and bile salt transport GO:0015721 15 10 0,000 8,968E-03 0,02253911 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 8,968E-03 0,02251595 ! positive regulation of heart contraction GO:0045823 17 10 0,000 8,968E-03 0,02249283 ! lung alveolus development GO:0048286 26 10 0,000 8,968E-03 0,02246976 ! pathogenesis GO:0009405 17 10 0,000 8,968E-03 0,02244674 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 8,968E-03 0,02242377 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 8,968E-03 0,02240084 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 8,968E-03 0,02237796 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 8,968E-03 0,02235512 ! endoderm development GO:0007492 18 10 0,000 8,968E-03 0,02233233 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 8,968E-03 0,02230959 ! arginine catabolic process GO:0006527 17 10 0,000 8,968E-03 0,0222869 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 8,968E-03 0,02226425 ! proline metabolic process GO:0006560 13 10 0,000 8,968E-03 0,02224164 ! glucan biosynthetic process GO:0009250 14 10 0,000 8,968E-03 0,02221909 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 8,968E-03 0,02219657 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 8,968E-03 0,02217411 ! V(D)J recombination GO:0033151 34 10 0,000 8,968E-03 0,02215169 ! reverse cholesterol transport GO:0043691 19 10 0,000 8,968E-03 0,02212931 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 8,968E-03 0,02210698 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 19 10 0,000 8,968E-03 0,0220847 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 8,968E-03 0,02206246 ! regulation of sodium ion transport GO:0002028 26 10 0,000 8,968E-03 0,02204026 ! multicellular organism growth GO:0035264 19 10 0,000 8,968E-03 0,02201811 ! phagocytosis, engulfment GO:0006911 33 10 0,000 8,968E-03 0,021996 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 8,968E-03 0,02197394 ! ruffle organization GO:0031529 17 10 0,000 8,968E-03 0,02195192 ! epithelial cell development GO:0002064 21 10 0,000 8,968E-03 0,02192995 ! lens development in camera-type eye GO:0002088 17 10 0,000 8,968E-03 0,02190802 ! retinoic acid metabolic process GO:0042573 14 10 0,000 8,968E-03 0,02188613 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 8,968E-03 0,02186429 ! positive regulation of translational initiation GO:0045948 12 10 0,000 8,968E-03 0,02184249 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 8,968E-03 0,02182074 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 8,968E-03 0,02179902 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 8,968E-03 0,02177735 ! motor axon guidance GO:0008045 22 10 0,000 8,968E-03 0,02175573 ! copper ion homeostasis GO:0055070 13 10 0,000 8,968E-03 0,02173415 ! regulation of bone resorption GO:0045124 25 10 0,000 8,968E-03 0,02171261 ! protein heterooligomerization GO:0051291 17 10 0,000 8,968E-03 0,02169111 ! regulation of gliogenesis GO:0014013 23 10 0,000 8,968E-03 0,02166965 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 8,968E-03 0,02164824 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 8,968E-03 0,02162687 ! segment specification GO:0007379 15 10 0,000 8,968E-03 0,02160554 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 8,968E-03 0,02158426 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 8,968E-03 0,02156301 ! blastoderm segmentation GO:0007350 19 10 0,000 8,968E-03 0,02154181 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 8,968E-03 0,02152065 ! response to dsRNA GO:0043331 23 10 0,000 8,968E-03 0,02149953 ! DNA ligation GO:0006266 18 10 0,000 8,968E-03 0,02147845 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 8,968E-03 0,02145741 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 8,968E-03 0,02143642 ! melanosome localization GO:0032400 16 10 0,000 8,968E-03 0,02141546 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 8,968E-03 0,02139455 ! regulation of B cell differentiation GO:0045577 24 10 0,000 8,968E-03 0,02137368 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 8,968E-03 0,02135285 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 8,968E-03 0,02133205 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 8,968E-03 0,0213113 ! induction of an organ GO:0001759 17 10 0,000 8,968E-03 0,02129059 ! leukocyte activation during immune response GO:0002366 15 10 0,000 8,968E-03 0,02126992 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 8,968E-03 0,02124929 ! protein sumoylation GO:0016925 17 10 0,000 8,968E-03 0,0212287 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 8,968E-03 0,02120815 ! hindbrain morphogenesis GO:0021575 19 10 0,000 8,968E-03 0,02118764 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 8,968E-03 0,02116717 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 8,968E-03 0,02114674 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 8,968E-03 0,02112634 ! salivary gland development GO:0007431 28 10 0,000 8,968E-03 0,02110599 ! ubiquinone metabolic process GO:0006743 17 10 0,000 8,968E-03 0,02108568 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 8,968E-03 0,0210654 ! midbrain development GO:0030901 14 10 0,000 8,968E-03 0,02104517 ! musculoskeletal movement GO:0050881 16 10 0,000 8,968E-03 0,02102497 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 8,968E-03 0,02100481 ! methionine biosynthetic process GO:0009086 21 10 0,000 8,968E-03 0,02098469 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 8,968E-03 0,02096461 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 8,968E-03 0,02094457 ! quaternary ammonium group transport GO:0015697 22 10 0,000 8,968E-03 0,02092456 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 8,968E-03 0,0209046 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 8,968E-03 0,02088467 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 8,968E-03 0,02086478 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 8,968E-03 0,02084493 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 8,968E-03 0,02082511 ! establishment of pigment granule localization GO:0051905 18 10 0,000 8,968E-03 0,02080534 ! blastocyst formation GO:0001825 18 10 0,000 8,968E-03 0,0207856 ! regulation of fibrinolysis GO:0051917 20 10 0,000 8,968E-03 0,02076589 ! cerebellar cortex development GO:0021695 16 10 0,000 8,968E-03 0,02074623 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 8,968E-03 0,0207266 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 8,968E-03 0,02070701 ! response to nicotine GO:0035094 20 10 0,000 8,968E-03 0,02068746 ! negative regulation of immune effector process GO:0002698 23 10 0,000 8,968E-03 0,02066794 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 8,968E-03 0,02064846 ! negative regulation of muscle development GO:0048635 27 11 0,000 9,86E-03 0,02268204 ! respiratory burst GO:0045730 17 11 0,000 9,86E-03 0,0226607 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 9,86E-03 0,0226394 ! neuron fate specification GO:0048665 18 11 0,000 9,86E-03 0,02261814 ! telencephalon cell migration GO:0022029 23 11 0,000 9,86E-03 0,02259693 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 9,86E-03 0,02257575 ! thyroid gland development GO:0030878 26 11 0,000 9,86E-03 0,02255461 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 9,86E-03 0,02253351 ! synapsis GO:0007129 14 11 0,000 9,86E-03 0,02251245 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 9,86E-03 0,02249143 ! Golgi vesicle budding GO:0048194 26 11 0,000 9,86E-03 0,02247045 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 9,86E-03 0,02244951 ! response to pain GO:0048265 27 11 0,000 9,86E-03 0,02242861 ! detection of mechanical stimulus GO:0050982 22 11 0,000 9,86E-03 0,02240774 ! blood vessel remodeling GO:0001974 30 11 0,000 9,86E-03 0,02238692 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 9,86E-03 0,02236613 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 9,86E-03 0,02234538 ! bone resorption GO:0045453 16 11 0,000 9,86E-03 0,02232467 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 9,86E-03 0,022304 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 9,86E-03 0,02228337 ! negative regulation of proteolysis GO:0045861 25 11 0,000 9,86E-03 0,02226278 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 9,86E-03 0,02224222 ! melanocyte differentiation GO:0030318 20 11 0,000 9,86E-03 0,0222217 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 9,86E-03 0,02220122 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 9,86E-03 0,02218078 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 9,86E-03 0,02216037 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 9,86E-03 0,02214 ! regulation of intracellular pH GO:0051453 21 11 0,000 9,86E-03 0,02211967 ! UV protection GO:0009650 20 11 0,000 9,86E-03 0,02209938 ! adult heart development GO:0007512 16 11 0,000 9,86E-03 0,02207912 ! chondrocyte differentiation GO:0002062 27 11 0,000 9,86E-03 0,0220589 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 9,86E-03 0,02203872 ! macroautophagy GO:0016236 19 11 0,000 9,86E-03 0,02201858 ! temperature homeostasis GO:0001659 18 11 0,000 9,86E-03 0,02199847 ! behavioral fear response GO:0001662 27 11 0,000 9,86E-03 0,0219784 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 9,86E-03 0,02195836 ! negative regulation of ossification GO:0030279 27 11 0,000 9,86E-03 0,02193836 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 9,86E-03 0,0219184 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 9,86E-03 0,02189848 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 9,86E-03 0,02187859 ! alpha-beta T cell activation GO:0046631 26 11 0,000 9,86E-03 0,02185873 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 9,86E-03 0,02183892 ! regulation of organ growth GO:0046620 14 11 0,000 9,86E-03 0,02181913 ! pigment granule localization GO:0051875 20 11 0,000 9,86E-03 0,02179939 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 9,86E-03 0,02177968 ! vasoconstriction GO:0042310 20 11 0,000 9,86E-03 0,02176 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 9,86E-03 0,02174036 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 9,86E-03 0,02172076 ! embryonic axis specification GO:0000578 19 11 0,000 9,86E-03 0,02170119 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 9,86E-03 0,02168166 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 9,86E-03 0,02166216 ! nitric oxide metabolic process GO:0046209 17 11 0,000 9,86E-03 0,0216427 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 9,86E-03 0,02162327 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 9,86E-03 0,02160388 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 9,86E-03 0,02158452 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 9,86E-03 0,0215652 ! prophase GO:0051324 17 11 0,000 9,86E-03 0,02154591 ! neuroblast proliferation GO:0007405 25 11 0,000 9,86E-03 0,02152665 ! nucleosome positioning GO:0016584 15 11 0,000 9,86E-03 0,02150743 ! regulation of isotype switching GO:0045191 24 11 0,000 9,86E-03 0,02148825 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 9,86E-03 0,02146909 ! negative regulation of neurological system process GO:0031645 21 11 0,000 9,86E-03 0,02144998 ! apical protein localization GO:0045176 18 11 0,000 9,86E-03 0,02143089 ! acid secretion GO:0046717 20 11 0,000 9,86E-03 0,02141184 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 9,86E-03 0,02139283 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 9,86E-03 0,02137385 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 9,86E-03 0,0213549 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 9,86E-03 0,02133598 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 9,86E-03 0,0213171 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 9,86E-03 0,02129825 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 9,86E-03 0,02127944 ! cholesterol efflux GO:0033344 21 11 0,000 9,86E-03 0,02126066 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 9,86E-03 0,02124191 ! oocyte development GO:0048599 20 11 0,000 9,86E-03 0,02122319 ! negative regulation of glucose import GO:0046325 18 11 0,000 9,86E-03 0,02120451 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 9,86E-03 0,02118586 ! embryonic gut development GO:0048566 19 11 0,000 9,86E-03 0,02116724 ! regulation of organic acid transport GO:0032890 19 11 0,000 9,86E-03 0,02114866 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 9,86E-03 0,02113011 ! activation of innate immune response GO:0002218 16 11 0,000 9,86E-03 0,02111159 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 36 11 0,000 9,86E-03 0,0210931 ! lysogeny GO:0030069 22 11 0,000 9,86E-03 0,02107465 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 9,86E-03 0,02105623 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 9,86E-03 0,02103784 ! sequestering of metal ion GO:0051238 15 11 0,000 9,86E-03 0,02101948 ! regulation of embryonic development GO:0045995 35 11 0,000 9,86E-03 0,02100115 ! nucleus localization GO:0051647 22 11 0,000 9,86E-03 0,02098286 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01075183 0,02286051 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01075183 0,02284063 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01075183 0,02282079 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01075183 0,02280098 ! virus-host interaction GO:0019048 30 12 0,000 0,01075183 0,0227812 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,01075183 0,02276146 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01075183 0,02274175 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01075183 0,02272208 ! protein complex disassembly GO:0043241 28 12 0,000 0,01075183 0,02270244 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01075183 0,02268284 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01075183 0,02266327 ! hippocampus development GO:0021766 29 12 0,000 0,01075183 0,02264373 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01075183 0,02262423 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01075183 0,02260476 ! T cell proliferation GO:0042098 32 12 0,000 0,01075183 0,02258532 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01075183 0,02256592 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01075183 0,02254655 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01075183 0,02252721 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01075183 0,02250791 ! drug transport GO:0015893 16 12 0,000 0,01075183 0,02248864 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01075183 0,0224694 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01075183 0,02245019 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01075183 0,02243102 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01075183 0,02241188 ! focal adhesion formation GO:0048041 37 12 0,000 0,01075183 0,02239278 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01075183 0,0223737 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01075183 0,02235466 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01075183 0,02233565 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01075183 0,02231667 ! lipid digestion GO:0044241 21 12 0,000 0,01075183 0,02229773 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01075183 0,02227882 ! entry into host cell GO:0030260 34 12 0,000 0,01075183 0,02225994 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01075183 0,02224109 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01075183 0,02222227 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01075183 0,02220349 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01075183 0,02218473 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01075183 0,02216601 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01075183 0,02214732 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01075183 0,02212867 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01075183 0,02211004 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01075183 0,02209144 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01075183 0,02207288 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01075183 0,02205435 ! cranial nerve development GO:0021545 23 12 0,000 0,01075183 0,02203584 ! fucose catabolic process GO:0019317 25 12 0,000 0,01075183 0,02201737 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01075183 0,02199893 ! histone acetylation GO:0016573 27 12 0,000 0,01075183 0,02198052 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01075183 0,02196215 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01075183 0,0219438 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01075183 0,02192548 ! zymogen activation GO:0031638 18 12 0,000 0,01075183 0,02190719 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01075183 0,02188894 ! T cell homeostasis GO:0043029 28 12 0,000 0,01075183 0,02187071 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01075183 0,02185252 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01075183 0,02183435 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01075183 0,02181622 ! oocyte differentiation GO:0009994 21 12 0,000 0,01075183 0,02179811 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01075183 0,02178004 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01075183 0,02176199 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01075183 0,02174398 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01075183 0,02172599 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01075183 0,02170804 ! defense response to fungus GO:0050832 15 12 0,000 0,01075183 0,02169011 ! developmental induction GO:0031128 22 12 0,000 0,01075183 0,02167222 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01075183 0,02165435 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01075183 0,02163651 ! response to cold GO:0009409 17 12 0,000 0,01075183 0,0216187 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01075183 0,02160093 ! localization within membrane GO:0051668 26 12 0,000 0,01075183 0,02158318 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01164275 0,0233524 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01164275 0,02333325 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01164275 0,02331412 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01164275 0,02329503 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01164275 0,02327596 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01164275 0,02325693 ! peroxisomal transport GO:0043574 28 13 0,000 0,01164275 0,02323793 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01164275 0,02321896 ! cartilage condensation GO:0001502 22 13 0,000 0,01164275 0,02320002 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01164275 0,02318111 ! organelle fusion GO:0048284 36 13 0,000 0,01164275 0,02316224 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01164275 0,02314339 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01164275 0,02312458 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01164275 0,02310579 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01164275 0,02308704 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01164275 0,02306831 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01164275 0,02304962 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01164275 0,02303095 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01164275 0,02301232 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01164275 0,02299372 ! methionine metabolic process GO:0006555 31 13 0,000 0,01164275 0,02297514 ! plasma membrane organization GO:0007009 27 13 0,000 0,01164275 0,0229566 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01164275 0,02293809 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01164275 0,0229196 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01164275 0,02290115 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01164275 0,02288273 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01164275 0,02286433 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01164275 0,02284597 ! exocrine system development GO:0035272 34 13 0,000 0,01164275 0,02282763 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01164275 0,02280932 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01164275 0,02279105 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01164275 0,0227728 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01164275 0,02275458 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01164275 0,02273639 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01164275 0,02271823 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01164275 0,0227001 ! protein homotetramerization GO:0051289 24 13 0,000 0,01164275 0,022682 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01164275 0,02266393 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01164275 0,02264588 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01164275 0,02262787 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01164275 0,02260988 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01164275 0,02259192 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01164275 0,02257399 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01164275 0,02255609 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01164275 0,02253822 ! histone methylation GO:0016571 29 13 0,000 0,01164275 0,02252037 ! chromatin silencing GO:0006342 29 13 0,000 0,01164275 0,02250255 ! gland morphogenesis GO:0022612 31 13 0,000 0,01164275 0,02248477 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01164275 0,022467 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01164275 0,02244927 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01164275 0,02243157 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01164275 0,02241389 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01164275 0,02239624 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01164275 0,02237862 ! spleen development GO:0048536 24 13 0,000 0,01164275 0,02236103 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01164275 0,02234346 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01164275 0,02232592 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01164275 0,02230841 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01164275 0,02229093 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01164275 0,02227348 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01164275 0,02225605 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01164275 0,02223865 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01164275 0,02222127 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01164275 0,02220392 ! insulin secretion GO:0030073 24 13 0,000 0,01164275 0,02218661 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01164275 0,02216931 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01164275 0,02215205 ! acrosome reaction GO:0007340 19 13 0,000 0,01164275 0,02213481 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01164275 0,0221176 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01164275 0,02210041 ! rRNA transcription GO:0009303 28 14 0,000 0,01253288 0,02377161 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01253288 0,02375317 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01253288 0,02373475 ! water transport GO:0006833 21 14 0,000 0,01253288 0,02371637 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01253288 0,02369801 ! non-recombinational repair GO:0000726 29 14 0,000 0,01253288 0,02367968 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01253288 0,02366138 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01253288 0,02364311 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01253288 0,02362487 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01253288 0,02360665 ! lipid localization GO:0010876 32 14 0,000 0,01253288 0,02358847 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01253288 0,02357031 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01253288 0,02355218 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01253288 0,02353407 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01253288 0,023516 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01253288 0,02349795 ! arginine metabolic process GO:0006525 21 14 0,000 0,01253288 0,02347993 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01253288 0,02346194 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01253288 0,02344397 ! regulation of heart rate GO:0002027 25 14 0,000 0,01253288 0,02342604 ! fear response GO:0042596 34 14 0,000 0,01253288 0,02340813 ! organic alcohol transport GO:0015850 29 14 0,000 0,01253288 0,02339025 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01253288 0,02337239 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01253288 0,02335456 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01253288 0,02333676 ! bone mineralization GO:0030282 18 14 0,000 0,01253288 0,02331899 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01253288 0,02330124 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01253288 0,02328352 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01253288 0,02326583 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01253288 0,02324816 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01253288 0,02323052 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01253288 0,02321291 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01253288 0,02319533 ! ribosome assembly GO:0042255 18 14 0,000 0,01253288 0,02317777 ! cerebellum development GO:0021549 23 14 0,000 0,01253288 0,02316024 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01253288 0,02314273 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01253288 0,02312525 ! response to gamma radiation GO:0010332 30 14 0,000 0,01253288 0,0231078 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01253288 0,02309037 ! NADP metabolic process GO:0006739 24 14 0,000 0,01253288 0,02307297 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01253288 0,0230556 ! oxygen transport GO:0015671 22 14 0,000 0,01253288 0,02303825 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01253288 0,02302093 ! male genitalia development GO:0030539 26 14 0,000 0,01253288 0,02300363 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01253288 0,02298636 ! regulation of axon extension GO:0030516 43 14 0,000 0,01253288 0,02296912 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01253288 0,0229519 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01253288 0,0229347 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01342224 0,02454381 ! lactation GO:0007595 30 15 0,000 0,01342224 0,02452546 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01342224 0,02450713 ! reproductive cellular process GO:0048610 22 15 0,000 0,01342224 0,02448882 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01342224 0,02447055 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01342224 0,0244523 ! superoxide anion generation GO:0042554 22 15 0,000 0,01342224 0,02443408 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01342224 0,02441589 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01342224 0,02439772 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01342224 0,02437958 ! copper ion transport GO:0006825 22 15 0,000 0,01342224 0,02436147 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01342224 0,02434338 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01342224 0,02432532 ! sulfate transport GO:0008272 27 15 0,000 0,01342224 0,02430729 ! response to cAMP GO:0051591 25 15 0,000 0,01342224 0,02428929 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01342224 0,02427131 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01342224 0,02425336 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01342224 0,02423543 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01342224 0,02421753 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01342224 0,02419966 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01342224 0,02418181 ! vesicle coating GO:0006901 38 15 0,000 0,01342224 0,02416399 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01342224 0,0241462 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01342224 0,02412843 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01342224 0,02411069 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01342224 0,02409297 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01342224 0,02407528 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01342224 0,02405762 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01342224 0,02403998 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01342224 0,02402237 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01342224 0,02400479 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01342224 0,02398722 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01342224 0,02396969 ! histone deacetylation GO:0016575 24 15 0,000 0,01342224 0,02395218 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01342224 0,0239347 ! water homeostasis GO:0030104 28 15 0,000 0,01342224 0,02391724 ! cofactor transport GO:0051181 30 15 0,000 0,01342224 0,02389981 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01342224 0,0238824 ! muscle maintenance GO:0046716 26 15 0,000 0,01342224 0,02386502 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01342224 0,02384766 ! intestinal absorption GO:0050892 31 15 0,000 0,01342224 0,02383033 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01342224 0,02381303 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01342224 0,02379574 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01342224 0,02377849 ! cell killing GO:0001906 32 15 0,000 0,01342224 0,02376126 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01342224 0,02374405 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01342224 0,02372687 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01342224 0,02370972 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01342224 0,02369258 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01342224 0,02367548 ! actin filament polymerization GO:0030041 27 15 0,000 0,01342224 0,0236584 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01342224 0,02364134 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01431083 0,02518829 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01431083 0,02517016 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01431083 0,02515205 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01431083 0,02513397 ! bone remodeling GO:0046849 28 16 0,000 0,01431083 0,02511591 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01431083 0,02509788 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01431083 0,02507988 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01431083 0,0250619 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01431083 0,02504394 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01431083 0,02502602 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01431083 0,02500812 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01431083 0,02499024 ! startle response GO:0001964 28 16 0,000 0,01431083 0,02497239 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01431083 0,02495457 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01431083 0,02493677 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01431083 0,02491899 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01431083 0,02490124 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01431083 0,02488352 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01431083 0,02486582 ! pituitary gland development GO:0021983 30 16 0,000 0,01431083 0,02484815 ! response to osmotic stress GO:0006970 27 16 0,000 0,01431083 0,0248305 ! lysosomal transport GO:0007041 31 16 0,000 0,01431083 0,02481288 ! L-amino acid transport GO:0015807 33 16 0,000 0,01431083 0,02479528 ! stem cell development GO:0048864 46 16 0,000 0,01431083 0,02477771 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01431083 0,02476016 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 0,01431083 0,02474264 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01431083 0,02472514 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01431083 0,02470767 ! axon cargo transport GO:0008088 46 16 0,000 0,01431083 0,02469022 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01431083 0,02467279 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01431083 0,02465539 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01431083 0,02463802 ! DNA replication initiation GO:0006270 28 16 0,000 0,01431083 0,02462067 ! neuron recognition GO:0008038 40 16 0,000 0,01431083 0,02460334 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01431083 0,02458604 ! tissue regeneration GO:0042246 27 16 0,000 0,01431083 0,02456876 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01431083 0,02455151 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01431083 0,02453428 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01431083 0,02451707 ! biomineral formation GO:0031214 22 16 0,000 0,01431083 0,02449989 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01431083 0,02448274 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01431083 0,0244656 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01431083 0,02444849 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01431083 0,02443141 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01431083 0,02441435 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01431083 0,02439731 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01431083 0,0243803 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01431083 0,02436331 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01431083 0,02434634 ! peptide hormone processing GO:0016486 27 16 0,000 0,01431083 0,0243294 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,01519863 0,02582077 ! metencephalon development GO:0022037 32 17 0,000 0,01519863 0,02580282 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,01519863 0,0257849 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,01519863 0,02576701 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,01519863 0,02574914 ! signal complex assembly GO:0007172 47 17 0,000 0,01519863 0,0257313 ! filopodium assembly GO:0046847 42 17 0,000 0,01519863 0,02571348 ! endothelial cell migration GO:0043542 31 17 0,000 0,01519863 0,02569568 ! gene silencing by RNA GO:0031047 38 17 0,000 0,01519863 0,02567791 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,01519863 0,02566017 ! glial cell development GO:0021782 28 17 0,000 0,01519863 0,02564245 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,01519863 0,02562475 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,01519863 0,02560708 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,01519863 0,02558943 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,01519863 0,02557181 ! myoblast differentiation GO:0045445 50 17 0,000 0,01519863 0,02555421 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,01519863 0,02553663 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,01519863 0,02551908 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,01519863 0,02550155 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,01519863 0,02548405 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,01519863 0,02546657 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,01519863 0,02544912 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,01519863 0,02543169 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,01519863 0,02541428 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,01519863 0,0253969 ! membrane budding GO:0006900 42 17 0,000 0,01519863 0,02537954 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,01519863 0,0253622 ! regulation of protein binding GO:0043393 33 17 0,000 0,01519863 0,02534489 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,01519863 0,0253276 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,01519863 0,02531034 ! genitalia development GO:0048806 32 17 0,000 0,01519863 0,02529309 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,01519863 0,02527588 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,01519863 0,02525868 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,01519863 0,02524151 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,01519863 0,02522436 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,01519863 0,02520724 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,01519863 0,02519014 ! steroid catabolic process GO:0006706 34 17 0,000 0,01519863 0,02517306 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,01519863 0,025156 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,01519863 0,02513897 ! gas transport GO:0015669 26 17 0,000 0,01519863 0,02512196 ! organic cation transport GO:0015695 32 17 0,000 0,01519863 0,02510498 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,01519863 0,02508801 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,01519863 0,02507107 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,01519863 0,02505416 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,01608567 0,02649851 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,01608567 0,02648065 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,01608567 0,02646282 ! limbic system development GO:0021761 40 18 0,000 0,01608567 0,02644501 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01608567 0,02642723 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,01608567 0,02640947 ! adult walking behavior GO:0007628 36 18 0,000 0,01608567 0,02639173 ! patterning of blood vessels GO:0001569 43 18 0,000 0,01608567 0,02637402 ! heart looping GO:0001947 34 18 0,000 0,01608567 0,02635633 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,01608567 0,02633866 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,01608567 0,02632102 ! centrosome cycle GO:0007098 26 18 0,000 0,01608567 0,0263034 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,01608567 0,02628581 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,01608567 0,02626824 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,01608567 0,02625069 ! glycine metabolic process GO:0006544 30 18 0,000 0,01608567 0,02623317 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01608567 0,02621567 ! response to retinoic acid GO:0032526 31 18 0,000 0,01608567 0,02619819 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,01608567 0,02618074 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,01608567 0,02616331 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,01608567 0,0261459 ! DNA integration GO:0015074 32 18 0,000 0,01608567 0,02612851 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,01608567 0,02611115 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,01608567 0,02609381 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,01608567 0,0260765 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,01608567 0,02605921 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,01608567 0,02604194 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,01608567 0,02602469 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,01608567 0,02600747 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,01608567 0,02599027 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,01608567 0,02597309 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,01608567 0,02595593 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,01608567 0,0259388 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,01608567 0,02592169 ! detection of bacterium GO:0016045 22 18 0,000 0,01608567 0,0259046 ! nerve development GO:0021675 34 18 0,000 0,01608567 0,02588754 ! defense response to virus GO:0051607 43 18 0,000 0,01608567 0,0258705 ! microspike assembly GO:0030035 46 18 0,000 0,01608567 0,02585348 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,01608567 0,02583648 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,01608567 0,0258195 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,01697193 0,02722417 ! positive regulation of translation GO:0045727 31 19 0,000 0,01697193 0,02720631 ! negative regulation of defense response GO:0031348 27 19 0,000 0,01697193 0,02718847 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,01697193 0,02717065 ! neuron maturation GO:0042551 46 19 0,000 0,01697193 0,02715286 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,01697193 0,02713509 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,01697193 0,02711734 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,01697193 0,02709962 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,01697193 0,02708192 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,01697193 0,02706424 ! inositol metabolic process GO:0006020 33 19 0,000 0,01697193 0,02704659 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01697193 0,02702896 ! memory GO:0007613 34 19 0,000 0,01697193 0,02701135 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,01697193 0,02699376 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,01697193 0,0269762 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,01697193 0,02695866 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,01697193 0,02694114 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,01697193 0,02692365 ! cerebral cortex development GO:0021987 40 19 0,000 0,01697193 0,02690618 ! pigmentation during development GO:0048066 42 19 0,000 0,01697193 0,02688873 ! response to vitamin A GO:0033189 32 19 0,000 0,01697193 0,0268713 ! heme metabolic process GO:0042168 40 19 0,000 0,01697193 0,0268539 ! neuromuscular junction development GO:0007528 43 19 0,000 0,01697193 0,02683652 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,01697193 0,02681916 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,01697193 0,02680182 ! response to fungus GO:0009620 26 19 0,000 0,01697193 0,02678451 ! peptide cross-linking GO:0018149 39 19 0,000 0,01697193 0,02676722 ! protein export from nucleus GO:0006611 40 19 0,000 0,01697193 0,02674995 ! heart process GO:0003015 32 19 0,000 0,01697193 0,0267327 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,01697193 0,02671548 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,01697193 0,02669827 ! visual learning GO:0008542 38 19 0,000 0,01697193 0,02668109 ! cellular pigmentation GO:0033059 37 19 0,000 0,01697193 0,02666393 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,01697193 0,0266468 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,01697193 0,02662968 ! vitamin transport GO:0051180 31 19 0,000 0,01697193 0,02661259 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,01697193 0,02659552 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,01697193 0,02657847 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,01697193 0,02656145 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,01697193 0,02654444 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,01697193 0,02652746 ! cilium assembly GO:0042384 38 19 0,000 0,01697193 0,0265105 ! peptide hormone secretion GO:0030072 32 19 0,000 0,01697193 0,02649356 ! protein secretion GO:0009306 45 20 0,000 0,01785741 0,02785802 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,01785741 0,02784024 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,01785741 0,02782249 ! positive regulation of ossification GO:0045778 50 20 0,000 0,01785741 0,02780475 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,01785741 0,02778704 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,01785741 0,02776936 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,01785741 0,02775169 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,01785741 0,02773405 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,01785741 0,02771643 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,01785741 0,02769883 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,01785741 0,02768126 ! response to vitamin GO:0033273 36 20 0,000 0,01785741 0,0276637 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,01785741 0,02764617 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,01785741 0,02762866 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,01785741 0,02761118 ! bile acid metabolic process GO:0008206 34 20 0,000 0,01785741 0,02759371 ! response to alkaloid GO:0043279 38 20 0,000 0,01785741 0,02757627 ! retinoid metabolic process GO:0001523 34 20 0,000 0,01785741 0,02755885 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,01785741 0,02754145 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,01785741 0,02752408 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,01785741 0,02750672 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,01785741 0,02748939 ! actin filament bundle formation GO:0051017 47 20 0,000 0,01785741 0,02747208 ! body fluid secretion GO:0007589 33 20 0,000 0,01785741 0,02745479 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,01785741 0,02743752 ! peptide secretion GO:0002790 38 20 0,000 0,01785741 0,02742028 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,01785741 0,02740305 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,01785741 0,02738585 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,01785741 0,02736867 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,01785741 0,02735151 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,01785741 0,02733437 ! cell-cell junction organization GO:0045216 43 20 0,000 0,01785741 0,02731726 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,01785741 0,02730016 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,01785741 0,02728309 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,01785741 0,02726604 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,01785741 0,02724901 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,01785741 0,027232 ! regulation of glucose import GO:0046324 30 20 0,000 0,01785741 0,02721501 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,01785741 0,02719804 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,01785741 0,0271811 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,01785741 0,02716417 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,01785741 0,02714727 ! regulation of cell killing GO:0031341 46 21 0,000 0,01874213 0,02847451 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,01874213 0,02845681 ! hormone secretion GO:0046879 39 21 0,000 0,01874213 0,02843914 ! lipid phosphorylation GO:0046834 43 21 0,000 0,01874213 0,02842149 ! cAMP metabolic process GO:0046058 41 21 0,000 0,01874213 0,02840386 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,01874213 0,02838625 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,01874213 0,02836866 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,01874213 0,02835109 ! ovarian follicle development GO:0001541 39 21 0,000 0,01874213 0,02833355 ! smooth muscle contraction GO:0006939 48 21 0,000 0,01874213 0,02831603 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,01874213 0,02829853 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,01874213 0,02828105 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,01874213 0,02826359 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,01874213 0,02824615 ! plasma membrane fusion GO:0045026 33 21 0,000 0,01874213 0,02822874 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,01874213 0,02821135 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,01874213 0,02819397 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,01874213 0,02817662 ! sensory perception of pain GO:0019233 33 21 0,000 0,01874213 0,0281593 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,01874213 0,02814199 ! diencephalon development GO:0021536 36 21 0,000 0,01874213 0,0281247 ! collagen fibril organization GO:0030199 62 21 0,000 0,01874213 0,02810744 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,01874213 0,02809019 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,01874213 0,02807297 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,01874213 0,02805577 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,01874213 0,02803859 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,01874213 0,02802143 ! collagen catabolic process GO:0030574 29 21 0,000 0,01874213 0,02800429 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,01874213 0,02798717 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,01874213 0,02797008 ! sperm-egg recognition GO:0035036 23 21 0,000 0,01874213 0,027953 ! actin filament-based movement GO:0030048 47 21 0,000 0,01874213 0,02793595 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,01874213 0,02791891 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,01962607 0,02921785 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,01962607 0,02920005 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,01962607 0,02918228 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,01962607 0,02916453 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,01962607 0,0291468 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,01962607 0,02912909 ! microtubule-based transport GO:0010970 59 22 0,000 0,01962607 0,02911141 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,01962607 0,02909374 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,01962607 0,0290761 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,01962607 0,02905848 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,01962607 0,02904087 ! cellular response to starvation GO:0009267 37 22 0,000 0,01962607 0,0290233 ! vacuolar transport GO:0007034 41 22 0,000 0,01962607 0,02900574 ! central nervous system neuron development GO:0021954 47 22 0,000 0,01962607 0,0289882 ! fucose metabolic process GO:0006004 44 22 0,000 0,01962607 0,02897069 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,01962607 0,02895319 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,01962607 0,02893572 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,01962607 0,02891827 ! ureteric bud development GO:0001657 50 22 0,000 0,01962607 0,02890083 ! cell aging GO:0007569 48 22 0,000 0,01962607 0,02888342 ! stem cell differentiation GO:0048863 57 22 0,000 0,01962607 0,02886604 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,01962607 0,02884867 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,01962607 0,02883132 ! cytolysis GO:0019835 27 22 0,000 0,01962607 0,02881399 ! renal system process GO:0003014 42 22 0,000 0,01962607 0,02879669 ! vasodilation GO:0042311 40 22 0,000 0,01962607 0,0287794 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,01962607 0,02876214 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,01962607 0,02874489 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,01962607 0,02872767 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,01962607 0,02871047 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,01962607 0,02869329 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,01962607 0,02867613 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,01962607 0,02865899 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,01962607 0,02864187 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,01962607 0,02862477 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,01962607 0,02860769 ! sarcomere organization GO:0045214 32 22 0,000 0,01962607 0,02859063 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,01962607 0,02857359 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,01962607 0,02855657 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,01962607 0,02853957 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,01962607 0,0285226 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,01962607 0,02850564 ! gut development GO:0048565 44 22 0,000 0,01962607 0,0284887 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,01962607 0,02847178 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,01962607 0,02845489 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,01962607 0,02843801 ! protein stabilization GO:0050821 41 22 0,000 0,01962607 0,02842115 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,02050924 0,02968251 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,02050924 0,02966493 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,02050924 0,02964738 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,02050924 0,02962985 ! gluconeogenesis GO:0006094 38 23 0,000 0,02050924 0,02961233 ! glycerol metabolic process GO:0006071 40 23 0,000 0,02050924 0,02959484 ! viral genome replication GO:0019079 44 23 0,000 0,02050924 0,02957737 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,02050924 0,02955992 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,02050924 0,02954249 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,02050924 0,02952508 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,02050924 0,0295077 ! regeneration GO:0031099 42 23 0,000 0,02050924 0,02949033 ! axis specification GO:0009798 43 23 0,000 0,02050924 0,02947298 ! visual behavior GO:0007632 46 23 0,000 0,02050924 0,02945565 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,02050924 0,02943835 ! response to ethanol GO:0045471 47 23 0,000 0,02050924 0,02942106 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,02050924 0,0294038 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,02050924 0,02938655 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,02050924 0,02936933 ! peroxisome organization GO:0007031 43 23 0,000 0,02050924 0,02935212 ! lysosome organization GO:0007040 47 23 0,000 0,02050924 0,02933493 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,02050924 0,02931777 ! vesicle targeting GO:0006903 49 23 0,000 0,02050924 0,02930062 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,02050924 0,0292835 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,02050924 0,0292664 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,02050924 0,02924931 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,02050924 0,02923225 ! DNA modification GO:0006304 36 23 0,000 0,02050924 0,0292152 ! fatty acid transport GO:0015908 47 23 0,000 0,02050924 0,02919818 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,02050924 0,02918117 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,02050924 0,02916418 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,02050924 0,02914722 ! hormone transport GO:0009914 41 23 0,000 0,02050924 0,02913027 ! cell-cell recognition GO:0009988 28 23 0,000 0,02050924 0,02911335 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,02050924 0,02909644 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,02050924 0,02907955 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,02050924 0,02906268 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,02139164 0,03029552 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,02139164 0,03027797 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,02139164 0,03026043 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,02139164 0,03024292 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,02139164 0,03022543 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,02139164 0,03020796 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,02139164 0,03019051 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,02139164 0,03017308 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,02139164 0,03015567 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,02139164 0,03013828 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,02139164 0,0301209 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,02139164 0,03010355 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,02139164 0,03008622 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,02139164 0,03006891 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,02139164 0,03005162 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,02139164 0,03003435 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,02139164 0,0300171 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,02139164 0,02999987 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,02139164 0,02998266 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,02139164 0,02996546 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,02139164 0,02994829 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,02139164 0,02993114 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,02139164 0,02991401 ! membrane depolarization GO:0051899 45 24 0,000 0,02139164 0,02989689 ! pallium development GO:0021543 56 24 0,000 0,02139164 0,0298798 ! oogenesis GO:0048477 44 24 0,000 0,02139164 0,02986273 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,02139164 0,02984567 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,02139164 0,02982864 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,02139164 0,02981162 ! platelet activation GO:0030168 41 24 0,000 0,02139164 0,02979462 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,02139164 0,02977765 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,02139164 0,02976069 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,02139164 0,02974375 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,02139164 0,02972683 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,02139164 0,02970993 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,02139164 0,02969305 ! regulation of amine transport GO:0051952 41 24 0,000 0,02139164 0,02967619 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,02139164 0,02965935 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02227327 0,0308642 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,02227327 0,03084671 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02227327 0,03082923 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,02227327 0,03081177 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02227327 0,03079434 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02227327 0,03077692 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02227327 0,03075952 ! phototransduction GO:0007602 37 25 0,000 0,02227327 0,03074214 ! keratinization GO:0031424 37 25 0,000 0,02227327 0,03072478 ! vasculogenesis GO:0001570 49 25 0,000 0,02227327 0,03070744 ! vacuole organization GO:0007033 49 25 0,000 0,02227327 0,03069012 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02227327 0,03067282 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02227327 0,03065554 ! receptor metabolic process GO:0043112 53 25 0,000 0,02227327 0,03063828 ! chromosome condensation GO:0030261 48 25 0,000 0,02227327 0,03062104 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02227327 0,03060382 ! regulation of behavior GO:0050795 48 25 0,000 0,02227327 0,03058662 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02227327 0,03056943 ! interaction with host GO:0051701 66 25 0,000 0,02227327 0,03055227 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02227327 0,03053512 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02227327 0,030518 ! immunoglobulin production GO:0002377 62 25 0,000 0,02227327 0,03050089 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02227327 0,0304838 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,02227327 0,03046674 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02227327 0,03044969 ! liver development GO:0001889 55 25 0,000 0,02227327 0,03043266 ! protein tetramerization GO:0051262 57 25 0,000 0,02227327 0,03041565 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,02315413 0,03160085 ! myelination GO:0042552 50 26 0,000 0,02315413 0,03158321 ! initiation of viral infection GO:0019059 60 26 0,000 0,02315413 0,03156559 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,02315413 0,03154798 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,02315413 0,0315304 ! molting cycle process GO:0022404 52 26 0,000 0,02315413 0,03151283 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,02315413 0,03149528 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,02315413 0,03147776 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,02315413 0,03146025 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,02315413 0,03144276 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,02315413 0,03142529 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,02315413 0,03140785 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,02315413 0,03139042 ! digestive system process GO:0022600 49 26 0,000 0,02315413 0,03137301 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,02315413 0,03135562 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,02315413 0,03133824 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,02315413 0,03132089 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,02315413 0,03130356 ! osteoblast differentiation GO:0001649 63 26 0,000 0,02315413 0,03128624 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,02315413 0,03126895 ! negative regulation of cell development GO:0010721 83 26 0,000 0,02315413 0,03125167 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,02315413 0,03123442 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,02315413 0,03121718 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,02315413 0,03119996 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,02315413 0,03118276 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,02315413 0,03116558 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,02315413 0,03114842 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,02315413 0,03113128 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,02315413 0,03111415 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,02315413 0,03109705 ! blastocyst development GO:0001824 50 26 0,000 0,02315413 0,03107996 ! telomere organization GO:0032200 46 26 0,000 0,02315413 0,03106289 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,02315413 0,03104585 ! neural tube closure GO:0001843 58 26 0,000 0,02315413 0,03102882 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,02315413 0,0310118 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,02315413 0,03099481 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02403422 0,03215531 ! embryonic pattern specification GO:0009880 49 27 0,000 0,02403422 0,03213771 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,02403422 0,03212013 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,02403422 0,03210257 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,02403422 0,03208502 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,02403422 0,0320675 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,02403422 0,03205 ! iron ion transport GO:0006826 65 27 0,000 0,02403422 0,03203251 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,02403422 0,03201504 ! superoxide metabolic process GO:0006801 41 27 0,000 0,02403422 0,0319976 ! tube lumen formation GO:0035148 59 27 0,000 0,02403422 0,03198017 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,02403422 0,03196276 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,02403422 0,03194537 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,02403422 0,031928 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,02403422 0,03191065 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,02403422 0,03189331 ! response to starvation GO:0042594 47 27 0,000 0,02403422 0,031876 ! response to toxin GO:0009636 49 27 0,000 0,02403422 0,0318587 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,02403422 0,03184143 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,02403422 0,03182417 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,02403422 0,03180693 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,02403422 0,03178971 ! leukocyte proliferation GO:0070661 59 27 0,000 0,02403422 0,03177251 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,02403422 0,03175532 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,02491354 0,03289934 ! neuron fate commitment GO:0048663 52 28 0,000 0,02491354 0,03288157 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,02491354 0,03286381 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,02491354 0,03284608 ! protein amino acid acylation GO:0043543 59 28 0,000 0,02491354 0,03282836 ! vesicle docking GO:0048278 55 28 0,000 0,02491354 0,03281066 ! circadian rhythm GO:0007623 56 28 0,000 0,02491354 0,03279298 ! dendrite development GO:0016358 67 28 0,000 0,02491354 0,03277532 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,02491354 0,03275768 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,02491354 0,03274006 ! base-excision repair GO:0006284 41 28 0,000 0,02491354 0,03272246 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,02491354 0,03270488 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,02491354 0,03268731 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,02491354 0,03266977 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,02491354 0,03265224 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,02491354 0,03263473 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,02491354 0,03261724 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,02491354 0,03259977 ! glutathione metabolic process GO:0006749 42 28 0,000 0,02491354 0,03258232 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,02491354 0,03256489 ! lipid oxidation GO:0034440 48 28 0,000 0,02491354 0,03254747 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,02491354 0,03253008 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,02491354 0,0325127 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,02579209 0,03364126 ! translational initiation GO:0006413 66 29 0,000 0,02579209 0,03362331 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,02579209 0,03360538 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,02579209 0,03358747 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,02579209 0,03356957 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,02579209 0,0335517 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,02579209 0,03353384 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,02579209 0,033516 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,02579209 0,03349819 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,02579209 0,03348039 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,02579209 0,03346261 ! somitogenesis GO:0001756 52 29 0,000 0,02579209 0,03344485 ! synaptogenesis GO:0007416 46 29 0,000 0,02579209 0,0334271 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,02579209 0,03340938 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,02579209 0,03339167 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,02579209 0,03337399 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,02579209 0,03335632 ! phenol metabolic process GO:0018958 56 30 0,000 0,02666988 0,03447329 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,02666988 0,03445506 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,02666988 0,03443685 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,02666988 0,03441866 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,02666988 0,03440049 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,02666988 0,03438234 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,02666988 0,0343642 ! acute-phase response GO:0006953 50 30 0,000 0,02666988 0,03434609 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,02666988 0,03432799 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,02666988 0,03430991 ! myofibril assembly GO:0030239 50 30 0,000 0,02666988 0,03429186 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,02666988 0,03427382 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,02666988 0,0342558 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,02666988 0,0342378 ! cell fate determination GO:0001709 64 30 0,000 0,02666988 0,03421981 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,02666988 0,03420185 ! phospholipid transport GO:0015914 65 30 0,000 0,02666988 0,03418391 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,02666988 0,03416598 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,02666988 0,03414807 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,02666988 0,03413019 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,02666988 0,03411232 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,02666988 0,03409447 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,02666988 0,03407663 ! regulation of coagulation GO:0050818 52 30 0,000 0,02666988 0,03405882 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,02754691 0,03516044 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,02754691 0,03514208 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,02754691 0,03512374 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,02754691 0,03510542 ! cell junction assembly GO:0034329 85 31 0,000 0,02754691 0,03508712 ! regulation of innate immune response GO:0045088 57 31 0,000 0,02754691 0,03506883 ! ovulation cycle process GO:0022602 55 31 0,000 0,02754691 0,03505057 ! peptide transport GO:0015833 60 31 0,000 0,02754691 0,03503232 ! male gonad development GO:0008584 56 31 0,000 0,02754691 0,03501409 ! iron ion homeostasis GO:0055072 60 31 0,000 0,02754691 0,03499589 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,02754691 0,0349777 ! detection of light stimulus GO:0009583 44 31 0,000 0,02754691 0,03495953 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,02754691 0,03494138 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,02754691 0,03492324 ! natural killer cell activation GO:0030101 50 31 0,000 0,02754691 0,03490513 ! ensheathment of neurons GO:0007272 64 31 0,000 0,02754691 0,03488703 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,02754691 0,03486896 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,02754691 0,0348509 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,02754691 0,03483286 ! eye morphogenesis GO:0048592 65 31 0,000 0,02754691 0,03481484 ! response to heat GO:0009408 54 31 0,000 0,02754691 0,03479684 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,02754691 0,03477886 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,02842316 0,03586662 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,02842316 0,03584811 ! collagen metabolic process GO:0032963 49 32 0,000 0,02842316 0,03582961 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,02842316 0,03581113 ! spindle organization GO:0007051 50 32 0,000 0,02842316 0,03579267 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,02842316 0,03577423 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,02842316 0,03575581 ! metanephros development GO:0001656 81 32 0,000 0,02842316 0,03573741 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,02842316 0,03571903 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,02842316 0,03570066 ! muscle cell development GO:0055001 52 32 0,000 0,02842316 0,03568231 ! mesoderm formation GO:0001707 73 32 0,000 0,02842316 0,03566399 ! ovulation cycle GO:0042698 57 32 0,000 0,02842316 0,03564568 ! peripheral nervous system development GO:0007422 68 32 0,000 0,02842316 0,03562739 ! BMP signaling pathway GO:0030509 71 32 0,000 0,02842316 0,03560912 ! hindbrain development GO:0030902 65 32 0,000 0,02842316 0,03559087 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,02842316 0,03557264 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,02842316 0,03555442 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,02842316 0,03553623 ! gene silencing GO:0016458 71 32 0,000 0,02842316 0,03551805 ! regulation of pH GO:0006885 56 33 0,000 0,02929865 0,03659336 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,02929865 0,03657466 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,02929865 0,03655598 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,02929865 0,03653732 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,02929865 0,03651868 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,02929865 0,03650006 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,02929865 0,03648145 ! response to ionizing radiation GO:0010212 74 33 0,000 0,02929865 0,03646287 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,02929865 0,0364443 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,02929865 0,03642576 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,02929865 0,03640723 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,02929865 0,03638872 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,02929865 0,03637023 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,02929865 0,03635176 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,02929865 0,03633331 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,03017338 0,03739907 ! glial cell differentiation GO:0010001 67 34 0,000 0,03017338 0,03738011 ! post-embryonic development GO:0009791 76 34 0,000 0,03017338 0,03736116 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,03017338 0,03734223 ! cholesterol transport GO:0030301 62 34 0,000 0,03017338 0,03732333 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,03017338 0,03730444 ! spliceosome assembly GO:0000245 75 34 0,000 0,03017338 0,03728557 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,03017338 0,03726672 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,03017338 0,03724789 ! formation of primary germ layer GO:0001704 76 34 0,000 0,03017338 0,03722908 ! cell fate specification GO:0001708 56 34 0,000 0,03017338 0,03721028 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,03017338 0,03719151 ! adult locomotory behavior GO:0008344 62 34 0,000 0,03017338 0,03717275 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,03017338 0,03715402 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,03104734 0,03821091 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,03104734 0,03819167 ! negative regulation of secretion GO:0051048 68 35 0,000 0,03104734 0,03817245 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,03104734 0,03815325 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,03104734 0,03813407 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,03104734 0,03811491 ! membrane docking GO:0022406 69 35 0,000 0,03104734 0,03809576 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,03104734 0,03807664 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,03104734 0,03805753 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,03104734 0,03803845 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,03104734 0,03801938 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,03104734 0,03800033 ! ceramide metabolic process GO:0006672 72 35 0,000 0,03104734 0,0379813 ! telencephalon development GO:0021537 81 35 0,000 0,03104734 0,03796229 ! sterol transport GO:0015918 63 35 0,000 0,03104734 0,0379433 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,03104734 0,03792433 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,03104734 0,03790538 ! placenta development GO:0001890 53 35 0,000 0,03104734 0,03788645 ! vesicle localization GO:0051648 70 35 0,000 0,03104734 0,03786753 ! regulation of muscle development GO:0048634 82 36 0,000 0,03192055 0,03891312 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,03192055 0,03889371 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,03192055 0,03887432 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,03192055 0,03885495 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,03192055 0,0388356 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,03192055 0,03881627 ! positive regulation of cell development GO:0010720 85 36 0,000 0,03192055 0,03879696 ! protein targeting to membrane GO:0006612 75 36 0,000 0,03192055 0,03877767 ! regulation of proteolysis GO:0030162 77 36 0,000 0,03192055 0,0387584 ! aerobic respiration GO:0009060 56 36 0,000 0,03192055 0,03873914 ! cytokine production GO:0001816 68 36 0,000 0,03192055 0,03871991 ! embryonic organ development GO:0048568 67 36 0,000 0,03192055 0,03870069 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,03192055 0,03868149 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,03279298 0,03971902 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,03279298 0,03969934 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,03279298 0,03967967 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,03279298 0,03966003 ! sister chromatid segregation GO:0000819 65 37 0,000 0,03279298 0,03964041 ! odontogenesis GO:0042476 74 37 0,000 0,03279298 0,0396208 ! actomyosin structure organization GO:0031032 68 37 0,000 0,03279298 0,03960122 ! cell junction organization GO:0034330 96 37 0,000 0,03279298 0,03958165 ! tissue remodeling GO:0048771 78 37 0,000 0,03279298 0,0395621 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,03279298 0,03954258 ! female gonad development GO:0008585 71 37 0,000 0,03279298 0,03952307 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,03279298 0,03950358 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,03279298 0,03948411 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,03279298 0,03946466 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,03279298 0,03944523 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,03366466 0,0404738 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,03366466 0,04045389 ! meiosis I GO:0007127 74 38 0,000 0,03366466 0,040434 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,03366466 0,04041414 ! organic anion transport GO:0015711 82 38 0,000 0,03366466 0,04039429 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,03366466 0,04037446 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,03366466 0,04035464 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,03366466 0,04033485 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,03366466 0,04031508 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,03366466 0,04029533 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,03366466 0,0402756 ! regulation of protein stability GO:0031647 77 38 0,000 0,03366466 0,04025588 ! spermatid development GO:0007286 69 38 0,000 0,03366466 0,04023619 ! glycogen metabolic process GO:0005977 63 38 0,000 0,03366466 0,04021651 ! pigment metabolic process GO:0042440 87 38 0,000 0,03366466 0,04019686 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,03366466 0,04017722 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,03453558 0,04119649 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,03453558 0,04117638 ! negative regulation of binding GO:0051100 71 39 0,000 0,03453558 0,0411563 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,03453558 0,04113623 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,03453558 0,04111619 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,03453558 0,04109616 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,03453558 0,04107615 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,03453558 0,04105616 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,03453558 0,04103619 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,03453558 0,04101624 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,03453558 0,04099631 ! glucan metabolic process GO:0044042 64 39 0,000 0,03453558 0,0409764 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,03540573 0,04198845 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,03540573 0,04196807 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,03540573 0,04194772 ! learning GO:0007612 82 40 0,000 0,03540573 0,04192739 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,03540573 0,04190707 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,03540573 0,04188678 ! lipid homeostasis GO:0055088 75 40 0,000 0,03540573 0,04186651 ! mismatch repair GO:0006298 58 40 0,000 0,03540573 0,04184625 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,03540573 0,04182602 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,03540573 0,0418058 ! mRNA catabolic process GO:0006402 79 41 0,000 0,03627513 0,04281166 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,03627513 0,04279099 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,03627513 0,04277034 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,03627513 0,0427497 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,03627513 0,04272909 ! gliogenesis GO:0042063 91 41 0,000 0,03627513 0,0427085 ! feeding behavior GO:0007631 69 41 0,000 0,03627513 0,04268793 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,03627513 0,04266737 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,03627513 0,04264684 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,03627513 0,04262633 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,03627513 0,04260583 ! spermatid differentiation GO:0048515 73 41 0,000 0,03627513 0,04258536 ! RNA modification GO:0009451 64 41 0,000 0,03627513 0,04256491 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,03714376 0,04356323 ! ear morphogenesis GO:0042471 64 42 0,000 0,03714376 0,04354233 ! organic ether metabolic process GO:0018904 59 42 0,000 0,03714376 0,04352145 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,03714376 0,04350058 ! T cell differentiation GO:0030217 93 42 0,000 0,03714376 0,04347974 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,03714376 0,04345891 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,03714376 0,04343811 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,03714376 0,04341733 ! regulation of protein secretion GO:0050708 77 42 0,000 0,03714376 0,04339656 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,03714376 0,04337582 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,03714376 0,04335509 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,03801164 0,04434691 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,03801164 0,04432575 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,03801164 0,0443046 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,03801164 0,04428347 ! regulation of tube size GO:0035150 76 43 0,000 0,03801164 0,04426236 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,03801164 0,04424128 ! glucose transport GO:0015758 66 43 0,000 0,03801164 0,04422021 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,03801164 0,04419916 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,03801164 0,04417813 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,03801164 0,04415713 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,03801164 0,04413614 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,03801164 0,04411517 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,03801164 0,04409423 ! segmentation GO:0035282 78 43 0,000 0,03801164 0,0440733 ! ion transmembrane transport GO:0034220 79 43 0,000 0,03801164 0,04405239 ! neuron migration GO:0001764 85 43 0,000 0,03801164 0,0440315 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,03801164 0,04401063 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,03887876 0,04499328 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,03887876 0,04497198 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,03887876 0,04495069 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,03887876 0,04492943 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,03887876 0,04490819 ! hexose transport GO:0008645 68 44 0,000 0,03887876 0,04488696 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,03887876 0,04486576 ! striated muscle contraction GO:0006941 85 44 0,000 0,03887876 0,04484458 ! phagocytosis GO:0006909 105 44 0,000 0,03887876 0,04482341 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,03887876 0,04480227 ! double-strand break repair GO:0006302 85 44 0,000 0,03887876 0,04478115 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,03974512 0,04575746 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,03974512 0,04573591 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,03974512 0,04571438 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,03974512 0,04569286 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,03974512 0,04567137 ! B cell differentiation GO:0030183 124 45 0,000 0,03974512 0,0456499 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,03974512 0,04562845 ! female gamete generation GO:0007292 71 45 0,000 0,03974512 0,04560702 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,03974512 0,0455856 ! developmental growth GO:0048589 88 45 0,000 0,03974512 0,04556421 ! maintenance of location in cell GO:0051651 101 45 0,000 0,03974512 0,04554284 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,04061073 0,0465129 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,04061073 0,0464911 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,04061073 0,04646933 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,04061073 0,04644757 ! leukocyte migration GO:0050900 75 46 0,000 0,04061073 0,04642584 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,04061073 0,04640412 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,04061073 0,04638243 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,04061073 0,04636075 ! pigmentation GO:0043473 103 46 0,000 0,04061073 0,0463391 ! cell growth GO:0016049 90 46 0,000 0,04061073 0,04631747 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,04061073 0,04629585 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,04147558 0,04725972 ! positive regulation of defense response GO:0031349 88 48 0,000 0,04233968 0,04822183 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,04233968 0,04819936 ! mitochondrial transport GO:0006839 94 48 0,000 0,04233968 0,04817691 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,04233968 0,04815448 ! cellular component disassembly GO:0022411 89 48 0,000 0,04233968 0,04813207 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,04233968 0,04810969 ! endosome transport GO:0016197 127 48 0,000 0,04233968 0,04808732 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,04233968 0,04806498 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,04233968 0,04804265 ! male sex differentiation GO:0046661 93 48 0,000 0,04233968 0,04802035 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,04233968 0,04799806 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,04233968 0,0479758 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,04233968 0,04795356 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,04233968 0,04793134 ! methylation GO:0032259 97 48 0,000 0,04233968 0,04790914 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,04320302 0,04886341 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,04320302 0,0488408 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,04320302 0,04881821 ! JNK cascade GO:0007254 106 49 0,000 0,04320302 0,04879564 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,04320302 0,04877309 ! protein homooligomerization GO:0051260 84 49 0,000 0,04320302 0,04875056 ! regulation of action potential GO:0001508 102 50 0,000 0,0440656 0,04970095 ! regulation of ion transport GO:0043269 86 50 0,000 0,0440656 0,04967802 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,0440656 0,0496551 ! endocrine system development GO:0035270 109 50 0,000 0,0440656 0,04963221 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,0440656 0,04960934 ! activation of caspase activity GO:0006919 95 50 0,000 0,0440656 0,04958649 ! regulation of ossification GO:0030278 123 50 0,000 0,0440656 0,04956366 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,0440656 0,04954085 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,0440656 0,04951806 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,0440656 0,04949529 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,0440656 0,04947255 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,04492744 0,05041696 ! viral infectious cycle GO:0019058 104 51 0,000 0,04492744 0,05039381 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,04492744 0,05037069 ! peptide metabolic process GO:0006518 80 51 0,000 0,04492744 0,05034758 ! response to temperature stimulus GO:0009266 84 51 0,000 0,04492744 0,0503245 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,04492744 0,05030143 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,04492744 0,05027839 ! positive regulation of binding GO:0051099 88 52 0,000 0,04578852 0,05121856 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,04578852 0,05119512 ! Notch signaling pathway GO:0007219 111 52 0,000 0,04578852 0,0511717 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,04578852 0,05114831 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,04578852 0,05112493 ! excretion GO:0007588 87 52 0,000 0,04578852 0,05110157 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,04578852 0,05107824 ! histone modification GO:0016570 104 52 0,000 0,04578852 0,05105493 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,04578852 0,05103163 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,04578852 0,05100836 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,04578852 0,05098512 ! amino acid activation GO:0043038 98 52 0,000 0,04578852 0,05096189 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,04664884 0,05189578 ! inner ear development GO:0048839 89 53 0,000 0,04664884 0,05187216 ! chromatin remodeling GO:0006338 122 53 0,000 0,04664884 0,05184856 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,04664884 0,05182498 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,04664884 0,05180142 ! vesicle organization GO:0016050 127 53 0,000 0,04664884 0,05177789 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,04664884 0,05175437 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,04664884 0,05173088 ! cartilage development GO:0051216 99 53 0,000 0,04664884 0,05170741 ! synapse organization GO:0050808 102 53 0,000 0,04664884 0,05168396 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,04750842 0,05261245 ! regulation of translational initiation GO:0006446 87 54 0,000 0,04750842 0,05258861 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,04750842 0,0525648 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,04750842 0,052541 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,04750842 0,05251723 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,04750842 0,05249347 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,04750842 0,05246974 ! membrane fusion GO:0006944 122 54 0,000 0,04750842 0,05244603 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,04750842 0,05242234 ! covalent chromatin modification GO:0016569 115 54 0,000 0,04750842 0,05239868 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,04750842 0,05237503 ! regulation of cell shape GO:0008360 142 54 0,000 0,04750842 0,05235141 ! RNA catabolic process GO:0006401 103 55 0,000 0,04836725 0,05327375 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,04836725 0,05324974 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,04836725 0,05322576 ! cell recognition GO:0008037 98 55 0,000 0,04836725 0,05320179 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,04836725 0,05317785 ! cell maturation GO:0048469 107 55 0,000 0,04836725 0,05315393 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,04836725 0,05313003 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,04836725 0,05310615 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,04922532 0,05402402 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,04922532 0,05399976 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,04922532 0,05397552 ! regulation of DNA replication GO:0006275 105 56 0,000 0,04922532 0,05395131 ! RNA elongation GO:0006354 90 56 0,000 0,04922532 0,05392711 ! chloride transport GO:0006821 102 57 0,000 0,05008265 0,05484173 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,05008265 0,05481716 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,05008265 0,05479262 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,05008265 0,05476809 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,05008265 0,05474358 ! heart morphogenesis GO:0003007 105 57 0,000 0,05008265 0,0547191 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,05008265 0,05469464 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,05008265 0,0546702 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,05093923 0,05558041 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,05093923 0,05555559 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,05093923 0,0555308 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,05093923 0,05550603 ! aging GO:0007568 112 58 0,000 0,05093923 0,05548129 ! gastrulation GO:0007369 122 58 0,000 0,05093923 0,05545656 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,05093923 0,05543186 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,05093923 0,05540718 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,05093923 0,05538252 ! maintenance of location GO:0051235 124 58 0,000 0,05093923 0,05535789 ! establishment of organelle localization GO:0051656 122 59 0,000 0,05179505 0,05626292 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,05265014 0,05716635 ! lipid modification GO:0030258 112 60 0,000 0,05265014 0,05714095 ! DNA catabolic process GO:0006308 94 60 0,000 0,05265014 0,05711558 ! regulation of endocytosis GO:0030100 104 60 0,000 0,05265014 0,05709023 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,05265014 0,0570649 ! adult behavior GO:0030534 104 60 0,000 0,05265014 0,05703959 ! kidney development GO:0001822 133 60 0,000 0,05265014 0,05701431 ! positive regulation of secretion GO:0051047 110 61 0,000 0,05350447 0,05791379 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,05350447 0,05788814 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,05350447 0,05786251 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,05350447 0,05783691 ! regulation of heart contraction GO:0008016 123 61 0,000 0,05350447 0,05781133 ! camera-type eye development GO:0043010 126 61 0,000 0,05350447 0,05778577 ! proton transport GO:0015992 117 61 0,000 0,05350447 0,05776024 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,05350447 0,05773473 ! viral reproductive process GO:0022415 132 62 0,000 0,05435806 0,0586299 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,05435806 0,05860403 ! tRNA processing GO:0008033 102 62 0,000 0,05435806 0,05857818 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,05435806 0,05855235 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,0552109 0,05944479 ! regulation of mitosis GO:0007088 112 63 0,000 0,0552109 0,0594186 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,0552109 0,05939244 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,0552109 0,0593663 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,0552109 0,05934018 ! hydrogen transport GO:0006818 121 64 0,000 0,056063 0,06022951 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,056063 0,06020303 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,056063 0,06017658 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,056063 0,06015015 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,05691435 0,06103677 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,05691435 0,06100998 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,05691435 0,06098323 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,05691435 0,06095649 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,05691435 0,06092978 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,05691435 0,06090309 ! ear development GO:0043583 114 66 0,000 0,05776496 0,06178625 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,05776496 0,06175921 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,05776496 0,06173219 ! gonad development GO:0008406 115 66 0,000 0,05776496 0,0617052 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,05776496 0,06167823 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,05861482 0,06255833 ! activation of MAPK activity GO:0000187 124 67 0,000 0,05861482 0,06253101 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,05861482 0,06250372 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,05861482 0,06247645 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,05861482 0,0624492 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,05861482 0,06242198 ! secondary metabolic process GO:0019748 125 67 0,000 0,05861482 0,06239478 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,05861482 0,0623676 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,05946395 0,06324354 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,05946395 0,06321602 ! extracellular matrix organization GO:0030198 146 68 0,000 0,05946395 0,06318852 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,05946395 0,06316105 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,05946395 0,0631336 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,05946395 0,06310618 ! viral reproduction GO:0016032 142 68 0,000 0,05946395 0,06307878 ! regulation of lipase activity GO:0060191 137 68 0,000 0,05946395 0,0630514 ! adaptive immune response GO:0002250 126 68 0,000 0,05946395 0,06302404 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell size GO:0045792 144 69 0,000 0,06031233 0,0638955 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,06031233 0,0638678 ! lung development GO:0030324 165 69 0,000 0,06031233 0,06384013 ! urogenital system development GO:0001655 149 69 0,000 0,06031233 0,06381248 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,06031233 0,06378485 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,06031233 0,06375725 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,06031233 0,06372968 ! developmental maturation GO:0021700 128 69 0,000 0,06031233 0,06370212 ! single fertilization GO:0007338 83 69 0,000 0,06031233 0,0636746 ! cell redox homeostasis GO:0045454 114 70 0,000 0,06115997 0,0645416 ! germ cell development GO:0007281 133 70 0,000 0,06115997 0,06451373 ! activation of immune response GO:0002253 120 70 0,000 0,06115997 0,06448589 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,06115997 0,06445807 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,06200686 0,06532245 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,06200686 0,0652943 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,06200686 0,06526617 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,06200686 0,06523806 ! appendage morphogenesis GO:0035107 150 72 0,000 0,06285302 0,06609984 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,06285302 0,0660714 ! respiratory tube development GO:0030323 171 72 0,000 0,06285302 0,06604298 ! B cell activation GO:0042113 179 72 0,000 0,06285302 0,06601459 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,06285302 0,06598622 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,06285302 0,06595788 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,06285302 0,06592956 ! appendage development GO:0048736 151 73 0,000 0,06369844 0,06678768 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,06369844 0,06675903 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,06369844 0,0667304 ! regulation of immune effector process GO:0002697 156 73 0,000 0,06369844 0,0667018 ! acute inflammatory response GO:0002526 118 74 0,000 0,06454312 0,06755735 ! amino acid transport GO:0006865 148 74 0,000 0,06454312 0,06752841 ! respiratory system development GO:0060541 175 74 0,000 0,06454312 0,06749951 ! organelle localization GO:0051640 155 74 0,000 0,06454312 0,06747062 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,06538706 0,06832361 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,06538706 0,0682944 ! reproductive structure development GO:0048608 131 75 0,000 0,06538706 0,06826521 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,06538706 0,06823605 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,06538706 0,06820692 ! eye development GO:0001654 155 75 0,000 0,06538706 0,0681778 ! rhythmic process GO:0048511 142 75 0,000 0,06538706 0,06814872 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,06623027 0,0689981 ! learning or memory GO:0007611 161 76 0,000 0,06623027 0,06896869 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,06623027 0,0689393 ! regulation of blood pressure GO:0008217 134 76 0,000 0,06623027 0,06890994 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,06623027 0,06888061 ! amine catabolic process GO:0009310 136 77 0,000 0,06707274 0,0697271 ! neurotransmitter transport GO:0006836 142 77 0,000 0,06707274 0,06969744 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,06707274 0,06966781 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,06707274 0,0696382 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,06707274 0,06960862 ! regulation of catabolic process GO:0009894 173 77 0,000 0,06707274 0,06957906 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,06791447 0,07042234 ! antigen processing and presentation GO:0019882 117 78 0,000 0,06791447 0,07039247 ! fertilization GO:0009566 99 78 0,000 0,06791447 0,07036261 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,06791447 0,07033279 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,06875546 0,07117356 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,06875546 0,07114341 ! protein oligomerization GO:0051259 149 79 0,000 0,06875546 0,07111329 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,06875546 0,0710832 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,06959572 0,07192147 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,06959572 0,07189106 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,06959572 0,07186067 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,06959572 0,07183031 ! meiosis GO:0007126 143 81 0,000 0,07043525 0,07266609 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,07043525 0,07263542 ! response to hypoxia GO:0001666 178 81 0,000 0,07043525 0,07260477 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,07043525 0,07257415 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,07127404 0,07340745 ! protein import into nucleus GO:0006606 174 82 0,000 0,07127404 0,07337652 ! meiotic cell cycle GO:0051321 144 82 0,000 0,07127404 0,07334561 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,0721121 0,07417678 ! exocytosis GO:0006887 153 83 0,000 0,0721121 0,07414556 ! response to drug GO:0042493 149 83 0,000 0,0721121 0,07411437 ! response to oxygen levels GO:0070482 183 83 0,000 0,0721121 0,0740832 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,0721121 0,07405206 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,0721121 0,07402095 ! nuclear import GO:0051170 177 83 0,000 0,0721121 0,07398986 ! inorganic anion transport GO:0015698 156 83 0,000 0,0721121 0,0739588 ! T cell activation GO:0042110 189 84 0,000 0,07294942 0,07478617 ! response to nutrient GO:0007584 135 84 0,000 0,07294942 0,0747548 ! digestion GO:0007586 130 84 0,000 0,07294942 0,07472346 ! negative regulation of transport GO:0051051 164 85 0,000 0,07378602 0,07554872 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,07378602 0,07551707 ! negative regulation of growth GO:0045926 168 85 0,000 0,07378602 0,07548544 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,07378602 0,07545385 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,07378602 0,07542228 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,07378602 0,07539073 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,07378602 0,07535921 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,07462188 0,07618105 ! regulation of lyase activity GO:0051339 169 86 0,000 0,07462188 0,07614923 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,07462188 0,07611743 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,07545701 0,07693718 ! nucleosome assembly GO:0006334 126 87 0,000 0,07545701 0,07690508 ! regulation of protein transport GO:0051223 165 87 0,000 0,07545701 0,07687301 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 0,000 0,07629141 0,07769067 ! sensory perception of smell GO:0007608 117 88 0,000 0,07629141 0,0776583 ! chromatin assembly GO:0031497 128 88 0,000 0,07629141 0,07762596 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,07629141 0,07759364 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,07712509 0,0784089 ! regulation of DNA binding GO:0051101 167 89 0,000 0,07712509 0,07837628 ! cellular defense response GO:0006968 123 89 0,000 0,07712509 0,07834369 ! protein localization in nucleus GO:0034504 192 89 0,000 0,07712509 0,07831113 ! regulation of neurological system process GO:0031644 175 89 0,000 0,07712509 0,0782786 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,07795803 0,07909114 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,07795803 0,07905831 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,07879024 0,07986911 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,07879024 0,07983599 ! gland development GO:0048732 220 91 0,000 0,07879024 0,07980289 ! defense response to bacterium GO:0042742 112 91 0,000 0,07879024 0,07976982 ! bone development GO:0060348 206 92 0,000 0,07962173 0,08057825 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,07962173 0,08054488 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,08045249 0,08135159 ! amine transport GO:0015837 181 93 0,000 0,08045249 0,08131793 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,08045249 0,0812843 ! vitamin metabolic process GO:0006766 153 93 0,000 0,08045249 0,0812507 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,08128252 0,08205504 ! female pregnancy GO:0007565 166 94 0,000 0,08128252 0,08202115 ! sterol metabolic process GO:0016125 166 94 0,000 0,08128252 0,08198729 ! regulation of membrane potential GO:0042391 179 94 0,000 0,08128252 0,08195345 ! regulation of defense response GO:0031347 171 95 0,000 0,08211183 0,08275545 ! nucleosome organization GO:0034728 143 95 0,000 0,08211183 0,08272132 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,08211183 0,08268722 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,08211183 0,08265315 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,08211183 0,08261911 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,08211183 0,0825851 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,08211183 0,08255111 ! sex differentiation GO:0007548 171 96 0,000 0,08294041 0,08334983 ! regulation of T cell activation GO:0050863 175 96 0,000 0,08294041 0,08331556 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,08376827 0,08411257 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,08376827 0,08407801 ! transcription initiation GO:0006352 171 97 0,000 0,08376827 0,08404349 ! regulation of protein localization GO:0032880 188 97 0,000 0,08376827 0,08400899 ! leukocyte differentiation GO:0002521 232 98 0,000 0,08459541 0,08480368 ! forebrain development GO:0030900 210 98 0,000 0,08459541 0,0847689 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,08459541 0,08473414 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,0862475 0,08635355 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,0862475 0,08631817 ! positive regulation of immune response GO:0050778 175 100 0,000 0,0862475 0,08628282 ! hormone metabolic process GO:0042445 171 100 0,000 0,0862475 0,0862475