pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/5704-7-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 7,000 3,378E-16 1,232E-12 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 5,000 5,374E-11 9,803E-08 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 5,000 7,206E-11 8,763E-08 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 5,000 8,694E-11 7,929E-08 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 5,000 9,529E-11 6,953E-08 ! positive regulation of ligase activity GO:0051351 86 70 5,000 1,14E-10 6,931E-08 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 5,000 1,745E-10 9,092E-08 ! regulation of ligase activity GO:0051340 95 78 5,000 2,221E-10 1,013E-07 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 5,000 3,252E-10 1,318E-07 GO:0010498|proteasomal protein catabolic process, ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 3,000 1,163E-09 4,242E-07 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 4,000 6,603E-09 2,19E-06 ! negative regulation of ligase activity GO:0051352 79 64 4,000 7,769E-09 2,362E-06 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein kinase regulator activity GO:0019887 74 66 4,000 9,093E-09 2,552E-06 ! kinase regulator activity GO:0019207 93 76 4,000 1,866E-08 4,863E-06 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 6,789E-08 1,651E-05 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 3,000 1,404E-07 3,2E-05 ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 2,000 6,749E-07 1,448E-04 ! interphase of mitotic cell cycle GO:0051329 100 81 3,000 1,841E-06 3,73E-04 ! interphase GO:0051325 103 83 3,000 2,03E-06 3,898E-04 ! spindle organization GO:0007051 38 27 2,000 3,498E-06 6,379E-04 ! protein kinase inhibitor activity GO:0004860 37 34 2,000 7,119E-06 1,237E-03 ! kinase inhibitor activity GO:0019210 47 35 2,000 7,781E-06 1,29E-03 ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 1,196E-05 1,897E-03 ! induction of apoptosis by intracellular signals GO:0008629 56 41 2,000 1,262E-05 1,918E-03 ! positive regulation of cell cycle GO:0045787 56 43 2,000 1,459E-05 2,129E-03 ! response to UV GO:0009411 59 45 2,000 1,675E-05 2,35E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 1,793E-05 2,423E-03 ! proteasome complex GO:0000502 50 48 2,000 2,037E-05 2,654E-03 ! proteasome regulatory particle GO:0005838 8 8 1,000 3,342E-05 4,204E-03 ! keratinocyte proliferation GO:0043616 9 8 1,000 3,342E-05 4,064E-03 ! negative regulation of protein kinase activity GO:0006469 78 64 2,000 4,851E-05 5,708E-03 ! negative regulation of kinase activity GO:0033673 79 65 2,000 5,082E-05 5,793E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 1,000 5,364E-05 5,93E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 1,000 5,364E-05 5,756E-03 ! negative regulation of transferase activity GO:0051348 85 70 2,000 6,346E-05 6,614E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 6,552E-05 6,639E-03 ! negative regulation of caspase activity GO:0043154 12 11 1,000 6,552E-05 6,46E-03 ! proteasome accessory complex GO:0022624 11 11 1,000 6,552E-05 6,29E-03 ! phosphoinositide-mediated signaling GO:0048015 92 74 2,000 7,493E-05 7,009E-03 ! regulation of exit from mitosis GO:0007096 31 12 1,000 7,857E-05 7,166E-03 ! midbody GO:0030496 14 12 1,000 7,857E-05 6,991E-03 ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 1,000 9,279E-05 8,06E-03 ! negative regulation of peptidase activity GO:0010466 16 14 1,000 1,082E-04 9,178E-03 ! positive regulation of cell growth GO:0030307 15 14 1,000 1,082E-04 8,97E-03 ! release of cytochrome c from mitochondria GO:0001836 26 14 1,000 1,082E-04 8,77E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 1,082E-04 8,58E-03 ! microtubule cytoskeleton organization GO:0000226 113 87 2,000 1,214E-04 9,421E-03 ! protein tyrosine phosphatase activity GO:0004725 109 89 2,000 1,299E-04 9,869E-03 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 1,000 1,425E-04 0,01060684 ! cell cycle arrest GO:0007050 103 93 2,000 1,48E-04 0,01079458 ! skin development GO:0043588 20 17 1,000 1,614E-04 0,01154186 ! positive regulation of cell size GO:0045793 19 18 1,000 1,814E-04 0,01272628 ! spindle microtubule GO:0005876 27 18 1,000 1,814E-04 0,01248616 ! response to light stimulus GO:0009416 131 100 2,000 1,834E-04 0,01239193 ! cellular response to unfolded protein GO:0034620 21 19 1,000 2,026E-04 0,01343857 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of fibroblast proliferation GO:0048146 25 19 1,000 2,026E-04 0,01319859 ! apoptotic mitochondrial changes GO:0008637 33 21 1,000 2,485E-04 0,01590291 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 1,000 2,485E-04 0,01562872 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 1,000 2,731E-04 0,01688878 ! positive regulation of B cell activation GO:0050871 26 22 1,000 2,731E-04 0,0166073 ! ubiquitin protein ligase binding GO:0031625 24 23 1,000 2,99E-04 0,01787867 ! positive regulation of nuclear division GO:0051785 35 23 1,000 2,99E-04 0,01759031 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 27 26 1,000 3,833E-04 0,0221925 ! regulation of fibroblast proliferation GO:0048145 32 26 1,000 3,833E-04 0,02184575 ! response to endoplasmic reticulum stress GO:0034976 30 26 1,000 3,833E-04 0,02150966 ! fat cell differentiation GO:0045444 30 27 1,000 4,136E-04 0,02286299 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 4,136E-04 0,02252175 ! negative regulation of phosphorylation GO:0042326 30 28 1,000 4,452E-04 0,02388136 ! ER-nuclear signaling pathway GO:0006984 32 29 1,000 4,778E-04 0,02526152 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 1,000 5,465E-04 0,02848067 GO:0045936|negative regulation of phosphate metabolic process, ! response to calcium ion GO:0051592 34 31 1,000 5,465E-04 0,02807953 ! meiosis I GO:0007127 53 32 1,000 5,825E-04 0,02951555 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 1,000 6,197E-04 0,03096842 ! negative regulation of hydrolase activity GO:0051346 36 34 1,000 6,58E-04 0,03243737 ! regulation of B cell activation GO:0050864 40 34 1,000 6,58E-04 0,03200487 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 1,000 7,379E-04 0,03542047 ! cellular response to extracellular stimulus GO:0031668 37 36 1,000 7,379E-04 0,03496046 ! positive regulation of mast cell proliferation GO:0070668 43 36 1,000 7,379E-04 0,03451225 GO:0050671|positive regulation of lymphocyte proliferation, ! positive regulation of leukocyte proliferation GO:0070665 47 37 1,000 7,796E-04 0,03599821 GO:0032946|positive regulation of mononuclear cell proliferation, ! protein serine/threonine phosphatase activity GO:0004722 45 42 1,000 1,004E-03 0,04580147 ! positive regulation of growth GO:0045927 47 43 1,000 1,053E-03 0,04741061 ! regulation of mast cell proliferation GO:0070666 57 49 1,000 1,365E-03 0,06074434 ! DNA damage response, signal transduction GO:0042770 84 50 1,000 1,421E-03 0,06247079 ! positive regulation of organelle organization GO:0010638 69 51 1,000 1,478E-03 0,06420318 ! regulation of lymphocyte proliferation GO:0050670 61 52 1,000 1,536E-03 0,0659412 ! keratinocyte differentiation GO:0030216 60 53 1,000 1,596E-03 0,06768458 ! regulation of leukocyte proliferation GO:0070663 65 53 1,000 1,596E-03 0,06690659 GO:0032944|regulation of mononuclear cell proliferation, ! regulation of mitosis GO:0007088 79 55 1,000 1,717E-03 0,07118625 GO:0051783|regulation of nuclear division, ! epidermal cell differentiation GO:0009913 66 58 1,000 1,908E-03 0,07819075 ! response to metal ion GO:0010038 65 60 1,000 2,04E-03 0,08268311 ! regulation of caspase activity GO:0043281 78 60 1,000 2,04E-03 0,0817745 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 1,000 2,176E-03 0,08629851 ! negative regulation of cell growth GO:0030308 69 63 1,000 2,246E-03 0,08811011 ! regulation of endopeptidase activity GO:0052548 81 63 1,000 2,246E-03 0,08717276 ! response to unfolded protein GO:0006986 66 64 1,000 2,317E-03 0,08897749 ! negative regulation of cell size GO:0045792 71 65 1,000 2,389E-03 0,0907846 ! positive regulation of lymphocyte activation GO:0051251 83 65 1,000 2,389E-03 0,08984868 ! response to inorganic substance GO:0010035 71 65 1,000 2,389E-03 0,08893185 ! regulation of peptidase activity GO:0052547 86 67 1,000 2,536E-03 0,09345173 ! positive regulation of phosphorylation GO:0042327 82 70 1,000 2,765E-03 0,100849 ! response to protein stimulus GO:0051789 73 70 1,000 2,765E-03 0,0998505 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 1,000 2,922E-03 0,10450306 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of leukocyte activation GO:0002696 92 73 1,000 3,002E-03 0,10633186 ! ubiquitin ligase complex GO:0000151 91 74 1,000 3,084E-03 0,10816169 ! regulation of cell cycle process GO:0010564 113 75 1,000 3,166E-03 0,10999245 ! positive regulation of cell activation GO:0050867 94 75 1,000 3,166E-03 0,10895479 ! meiosis GO:0007126 108 75 1,000 3,166E-03 0,10793652 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of growth GO:0045926 85 76 1,000 3,249E-03 0,10975322 ! meiotic cell cycle GO:0051321 109 76 1,000 3,249E-03 0,10874631 ! positive regulation of protein modification process GO:0031401 100 78 1,000 3,419E-03 0,1133895 ! protein ubiquitination GO:0016567 95 78 1,000 3,419E-03 0,11236797 ! mitochondrion organization GO:0007005 104 82 1,000 3,771E-03 0,12282569 ! protein modification by small protein conjugation GO:0032446 103 85 1,000 4,046E-03 0,13060188 ! protein kinase binding GO:0019901 115 89 1,000 4,426E-03 0,14162048 ! spindle GO:0005819 126 92 1,000 4,721E-03 0,14976529 ! protein modification by small protein conjugation or removal GO:0070647 112 93 1,000 4,822E-03 0,15163512 ! in utero embryonic development GO:0001701 110 96 1,000 5,129E-03 0,1599255 ! perinuclear region of cytoplasm GO:0048471 125 97 1,000 5,234E-03 0,16179943 ! regulation of lymphocyte activation GO:0051249 123 100 1,000 5,553E-03 0,1702261 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 5,597E-03 0,17014883 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 5,597E-03 0,16874264 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 5,597E-03 0,1673595 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 5,597E-03 0,16599886 ! response to superoxide GO:0000303 5 5 0,000 5,597E-03 0,16466016 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 5,597E-03 0,16334287 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 5,597E-03 0,1620465 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 5,597E-03 0,16077055 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 5,597E-03 0,15951453 ! quinolinate metabolic process GO:0046874 5 5 0,000 5,597E-03 0,15827798 ! biotin binding GO:0009374 7 5 0,000 5,597E-03 0,15706046 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 5,597E-03 0,15586152 ! tongue development GO:0043586 6 5 0,000 5,597E-03 0,15468075 ! nose development GO:0043584 5 5 0,000 5,597E-03 0,15351774 ! cell proliferation in forebrain GO:0021846 5 5 0,000 5,597E-03 0,15237208 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 5,597E-03 0,1512434 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 5,597E-03 0,15013132 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 5,597E-03 0,14903547 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 5,597E-03 0,1479555 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 5,597E-03 0,14689107 ! glycolipid transport GO:0046836 6 5 0,000 5,597E-03 0,14584185 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 5,597E-03 0,14480751 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 5,597E-03 0,14378774 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 5,597E-03 0,14278223 ! neuron adhesion GO:0007158 5 5 0,000 5,597E-03 0,14179069 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 5,597E-03 0,14081282 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 5,597E-03 0,13984835 ! opioid peptide activity GO:0001515 6 5 0,000 5,597E-03 0,138897 ! selenocysteine incorporation GO:0001514 5 5 0,000 5,597E-03 0,13795851 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 5,597E-03 0,13703261 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 5,597E-03 0,13611906 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 5,597E-03 0,13521761 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 5,597E-03 0,13432802 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 5,597E-03 0,13345006 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,597E-03 0,1325835 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 5,597E-03 0,13172812 ! clathrin coat assembly GO:0048268 6 5 0,000 5,597E-03 0,13088371 ! cerebral cortex cell migration GO:0021795 5 5 0,000 5,597E-03 0,13005006 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 5,597E-03 0,12922696 ! membrane hyperpolarization GO:0060081 5 5 0,000 5,597E-03 0,12841421 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 5,597E-03 0,12761162 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 5,597E-03 0,126819 ! translation repressor activity GO:0030371 8 5 0,000 5,597E-03 0,12603617 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 5,597E-03 0,12526294 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 5,597E-03 0,12449914 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 5,597E-03 0,1237446 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 5,597E-03 0,12299915 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 5,597E-03 0,12226263 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 5,597E-03 0,12153488 ! negative regulation of heart contraction GO:0045822 5 5 0,000 5,597E-03 0,12081574 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 5,597E-03 0,12010505 ! microfibril GO:0001527 5 5 0,000 5,597E-03 0,11940269 ! troponin I binding GO:0031013 5 5 0,000 5,597E-03 0,11870848 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 5,597E-03 0,11802231 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 5,597E-03 0,11734402 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 5,597E-03 0,11667348 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 5,597E-03 0,11601056 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 5,597E-03 0,11535514 ! protein lipoylation GO:0009249 14 5 0,000 5,597E-03 0,11470707 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,597E-03 0,11406625 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 5,597E-03 0,11343255 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 5,597E-03 0,11280585 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 5,597E-03 0,11218604 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 5,597E-03 0,111573 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 5,597E-03 0,11096663 ! glutamate catabolic process GO:0006538 6 5 0,000 5,597E-03 0,11036681 ! microvillus organization GO:0032528 5 5 0,000 5,597E-03 0,10977344 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 5,597E-03 0,10918641 ! tyrosine catabolic process GO:0006572 5 5 0,000 5,597E-03 0,10860563 ! response to pH GO:0009268 5 5 0,000 5,597E-03 0,108031 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 5,597E-03 0,10746242 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 5,597E-03 0,10689979 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 5,597E-03 0,10634302 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,597E-03 0,10579202 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 5,597E-03 0,1052467 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,597E-03 0,10470697 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 5,597E-03 0,10417275 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 5,597E-03 0,10364396 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 5,597E-03 0,1031205 ! anaerobic glycolysis GO:0019642 5 5 0,000 5,597E-03 0,10260231 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 5,597E-03 0,1020893 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 5,597E-03 0,10158139 ! peroxisomal matrix GO:0005782 5 5 0,000 5,597E-03 0,10107851 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 5,597E-03 0,10058059 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 5,597E-03 0,10008755 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 5,597E-03 0,09959931 ! multivesicular body GO:0005771 5 5 0,000 5,597E-03 0,09911582 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 5,597E-03 0,098637 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 5,597E-03 0,09816278 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 5,597E-03 0,09769311 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 5,597E-03 0,0972279 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 5,597E-03 0,09676711 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 5,597E-03 0,09631066 ! epithelial cell maturation GO:0002070 14 5 0,000 5,597E-03 0,09585849 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 5,597E-03 0,09541056 ! muscle thin filament assembly GO:0030240 5 5 0,000 5,597E-03 0,09496679 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 5,597E-03 0,09452713 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 5,597E-03 0,09409152 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 0,000 5,597E-03 0,0936599 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 5,597E-03 0,09323223 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,597E-03 0,09280845 ! positive regulation of translational initiation GO:0045948 6 5 0,000 5,597E-03 0,0923885 ! nonhomologous end joining complex GO:0070419 6 5 0,000 5,597E-03 0,09197234 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 5,597E-03 0,09155991 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 5,597E-03 0,09115116 ! ATPase activator activity GO:0001671 5 5 0,000 5,597E-03 0,09074604 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 5,597E-03 0,09034451 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 0,000 5,597E-03 0,08994652 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 5,597E-03 0,08955201 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 5,597E-03 0,08916096 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 5,597E-03 0,0887733 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 5,597E-03 0,088389 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 5,597E-03 0,08800801 ! cardiac myofibril assembly GO:0055003 5 5 0,000 5,597E-03 0,0876303 ! anterograde axon cargo transport GO:0008089 6 5 0,000 5,597E-03 0,08725581 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,597E-03 0,08688451 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 5,597E-03 0,08651635 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 5,597E-03 0,0861513 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 5,597E-03 0,08578932 ! protein localization to telomere GO:0070198 7 5 0,000 5,597E-03 0,08543037 ! response to exogenous dsRNA GO:0043330 5 5 0,000 5,597E-03 0,08507441 ! MutSalpha complex binding GO:0032407 7 5 0,000 5,597E-03 0,08472141 ! bile acid biosynthetic process GO:0006699 5 5 0,000 5,597E-03 0,08437132 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 5,597E-03 0,08402411 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 5,597E-03 0,08367975 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,597E-03 0,0833382 ! nerve growth factor binding GO:0048406 7 5 0,000 5,597E-03 0,08299943 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 5,597E-03 0,0826634 ! high-density lipoprotein binding GO:0008035 6 5 0,000 5,597E-03 0,08233008 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 5,597E-03 0,08199943 ! transcription initiation factor activity GO:0016986 5 5 0,000 5,597E-03 0,08167144 ! gas homeostasis GO:0033483 5 5 0,000 5,597E-03 0,08134605 ! Schwann cell development GO:0014044 5 5 0,000 5,597E-03 0,08102325 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 5,597E-03 0,080703 ! cyclohydrolase activity GO:0019238 5 5 0,000 5,597E-03 0,08038527 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,597E-03 0,08007004 ! response to pheromone GO:0019236 5 5 0,000 5,597E-03 0,07975726 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 5,597E-03 0,07944692 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 5,597E-03 0,07913899 ! rhombomere development GO:0021546 6 5 0,000 5,597E-03 0,07883343 ! alanine transport GO:0032328 6 5 0,000 5,597E-03 0,07853023 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 5,597E-03 0,07822935 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 5,597E-03 0,07793076 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 5,597E-03 0,07763445 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 5,597E-03 0,07734038 ! regulation of meiosis GO:0040020 6 5 0,000 5,597E-03 0,07704853 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 5,597E-03 0,07675887 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 5,597E-03 0,07647138 ! lymphocyte costimulation GO:0031294 5 5 0,000 5,597E-03 0,07618604 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 5,597E-03 0,07590282 ! RS domain binding GO:0050733 6 5 0,000 5,597E-03 0,0756217 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 5,597E-03 0,07534265 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 5,597E-03 0,07506566 ! B cell homeostasis GO:0001782 6 5 0,000 5,597E-03 0,07479069 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 5,597E-03 0,07451773 ! anaphase GO:0051322 7 5 0,000 5,597E-03 0,07424676 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 5,597E-03 0,07397775 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 5,597E-03 0,07371068 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 5,597E-03 0,07344554 ! AP-2 adaptor complex GO:0030122 5 5 0,000 5,597E-03 0,07318229 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 5,597E-03 0,07292093 ! diuresis GO:0030146 5 5 0,000 5,597E-03 0,07266142 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 5,597E-03 0,07240376 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 5,597E-03 0,07214791 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 5,597E-03 0,07189387 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 5,597E-03 0,07164161 ! GTP-Rho binding GO:0017049 5 5 0,000 5,597E-03 0,07139112 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 5,597E-03 0,07114237 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,597E-03 0,07089534 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 5,597E-03 0,07065003 ! brown fat cell differentiation GO:0050873 5 5 0,000 5,597E-03 0,07040641 ! regulation of telomerase activity GO:0051972 6 5 0,000 5,597E-03 0,07016446 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 5,597E-03 0,06992418 ! TAP complex GO:0042825 5 5 0,000 5,597E-03 0,06968553 ! platelet dense granule GO:0042827 6 5 0,000 5,597E-03 0,0694485 ! bHLH transcription factor binding GO:0043425 5 5 0,000 5,597E-03 0,06921308 ! secretory granule organization GO:0033363 5 5 0,000 5,597E-03 0,06897925 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 5,597E-03 0,068747 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 5,597E-03 0,06851631 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 5,597E-03 0,06828715 ! lamin binding GO:0005521 8 5 0,000 5,597E-03 0,06805953 ! aldehyde-lyase activity GO:0016832 6 5 0,000 5,597E-03 0,06783342 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,597E-03 0,06760881 ! neural plate morphogenesis GO:0001839 6 5 0,000 5,597E-03 0,06738567 ! cyclosporin A binding GO:0016018 6 5 0,000 5,597E-03 0,06716401 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 5,597E-03 0,0669438 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 5,597E-03 0,06672503 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 5,597E-03 0,06650768 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 5,597E-03 0,06629175 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 5,597E-03 0,06607721 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 5,597E-03 0,06586406 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 5,597E-03 0,06565228 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 5,597E-03 0,06544186 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 5,597E-03 0,06523278 ! organ or tissue specific immune response GO:0002251 6 5 0,000 5,597E-03 0,06502503 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 5,597E-03 0,0648186 ! retina homeostasis GO:0001895 5 5 0,000 5,597E-03 0,06461348 ! prepulse inhibition GO:0060134 8 5 0,000 5,597E-03 0,06440965 ! maternal placenta development GO:0001893 5 5 0,000 5,597E-03 0,0642071 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 5,597E-03 0,06400583 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 5,597E-03 0,06380581 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 5,597E-03 0,06360704 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 5,597E-03 0,0634095 ! protein palmitoylation GO:0018345 5 5 0,000 5,597E-03 0,06321319 ! protein amino acid prenylation GO:0018346 6 5 0,000 5,597E-03 0,06301808 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 5,597E-03 0,06282418 ! stem cell division GO:0017145 6 5 0,000 5,597E-03 0,06263147 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 5,597E-03 0,06243994 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 5,597E-03 0,06224957 ! organ regeneration GO:0031100 6 5 0,000 5,597E-03 0,06206036 ! lymphocyte apoptosis GO:0070227 6 5 0,000 5,597E-03 0,0618723 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 5,597E-03 0,06168538 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 5,597E-03 0,06149958 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 5,597E-03 0,06131489 ! acyl carrier activity GO:0000036 5 5 0,000 5,597E-03 0,06113132 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 5,597E-03 0,06094883 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 5,597E-03 0,06076744 ! phagocytic vesicle GO:0045335 5 5 0,000 5,597E-03 0,06058712 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 5,597E-03 0,06040787 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 5,597E-03 0,06022967 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 5,597E-03 0,06005253 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 5,597E-03 0,05987642 ! polyol transport GO:0015791 8 5 0,000 5,597E-03 0,05970134 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 5,597E-03 0,05952729 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 5,597E-03 0,05935424 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 5,597E-03 0,0591822 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 5,597E-03 0,05901115 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 5,597E-03 0,05884109 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 5,597E-03 0,05867201 ! ethanol metabolic process GO:0006067 6 5 0,000 5,597E-03 0,05850389 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 5,597E-03 0,05833674 ! cobalt ion transport GO:0006824 5 5 0,000 5,597E-03 0,05817054 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 5,597E-03 0,05800528 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 5,597E-03 0,05784096 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 5,597E-03 0,05767757 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 5,597E-03 0,0575151 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 5,597E-03 0,05735354 ! sterol carrier activity GO:0005498 6 5 0,000 5,597E-03 0,05719288 ! adaptation of signaling pathway GO:0022401 6 5 0,000 5,597E-03 0,05703313 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 5,597E-03 0,05687426 ! response to acid GO:0001101 7 5 0,000 5,597E-03 0,05671628 ! fibril organization GO:0043206 5 5 0,000 5,597E-03 0,05655917 ! malate metabolic process GO:0006108 6 5 0,000 5,597E-03 0,05640293 ! regulation of dopamine uptake GO:0051584 7 5 0,000 5,597E-03 0,05624755 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 5,597E-03 0,05609302 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 5,597E-03 0,05593934 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 5,597E-03 0,0557865 ! protein maturation by protein folding GO:0022417 5 5 0,000 5,597E-03 0,05563449 ! activation of protein kinase B activity GO:0032148 15 5 0,000 5,597E-03 0,05548331 ! origin recognition complex GO:0000808 5 5 0,000 5,597E-03 0,05533295 ! neurexin binding GO:0042043 6 5 0,000 5,597E-03 0,0551834 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 5,597E-03 0,05503466 ! protein amino acid dealkylation GO:0008214 5 5 0,000 5,597E-03 0,05488672 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 5,597E-03 0,05473957 ! lipoic acid binding GO:0031405 5 5 0,000 5,597E-03 0,05459321 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 5,597E-03 0,05444762 ! lithium ion binding GO:0031403 6 5 0,000 5,597E-03 0,05430282 ! grooming behavior GO:0007625 7 5 0,000 5,597E-03 0,05415878 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 5,597E-03 0,0540155 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 5,597E-03 0,05387298 ! lymph vessel development GO:0001945 6 5 0,000 5,597E-03 0,05373121 ! bicarbonate transport GO:0015701 5 5 0,000 5,597E-03 0,05359018 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 0,000 5,597E-03 0,05344989 GO:0010811|positive regulation of cell-substrate adhesion, ! response to interferon-gamma GO:0034341 6 5 0,000 5,597E-03 0,05331034 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 5,597E-03 0,05317151 ! endothelial cell proliferation GO:0001935 8 5 0,000 5,597E-03 0,0530334 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 5,597E-03 0,05289601 ! dorsal spinal cord development GO:0021516 6 5 0,000 5,597E-03 0,05275933 ! activation of MAPKKK activity GO:0000185 5 5 0,000 5,597E-03 0,05262335 ! synaptic vesicle maturation GO:0016188 6 5 0,000 5,597E-03 0,05248807 ! sphingoid catabolic process GO:0046521 5 5 0,000 5,597E-03 0,05235349 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 5,597E-03 0,05221959 ! neutrophil mediated immunity GO:0002446 5 5 0,000 5,597E-03 0,05208638 ! intercellular canaliculus GO:0046581 5 5 0,000 5,597E-03 0,05195384 ! dopamine binding GO:0035240 7 5 0,000 5,597E-03 0,05182198 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 5,597E-03 0,05169078 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 5,597E-03 0,05156025 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 5,597E-03 0,05143038 ! amine oxidase activity GO:0008131 7 5 0,000 5,597E-03 0,05130115 ! monocyte activation GO:0042117 9 5 0,000 5,597E-03 0,05117258 ! negative regulation of protein binding GO:0032091 5 5 0,000 5,597E-03 0,05104465 ! regulation of response to food GO:0032095 5 5 0,000 5,597E-03 0,05091735 ! response to food GO:0032094 6 5 0,000 5,597E-03 0,05079069 ! positive regulation of protein binding GO:0032092 5 5 0,000 5,597E-03 0,05066466 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 5,597E-03 0,05053926 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 5,597E-03 0,05041447 ! hedgehog receptor activity GO:0008158 5 5 0,000 5,597E-03 0,05029029 ! lipoprotein catabolic process GO:0042159 5 5 0,000 5,597E-03 0,05016673 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 5,597E-03 0,05004377 ! purine salvage GO:0043101 7 5 0,000 5,597E-03 0,04992142 ! small-subunit processome GO:0032040 5 5 0,000 5,597E-03 0,04979966 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 5,597E-03 0,04967849 ! ciliary rootlet GO:0035253 5 5 0,000 5,597E-03 0,04955791 ! myosin heavy chain binding GO:0032036 5 5 0,000 5,597E-03 0,04943792 ! nucleobase transport GO:0015851 5 5 0,000 5,597E-03 0,0493185 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 5,597E-03 0,04919966 ! GPI anchor binding GO:0034235 6 5 0,000 5,597E-03 0,04908139 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,597E-03 0,04896369 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 5,597E-03 0,04884655 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 5,597E-03 0,04872997 ! basic amino acid transport GO:0015802 5 5 0,000 5,597E-03 0,04861395 ! dendritic shaft GO:0043198 5 5 0,000 5,597E-03 0,04849848 ! terminal button GO:0043195 7 5 0,000 5,597E-03 0,04838355 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 5,597E-03 0,04826917 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 5,597E-03 0,04815533 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 5,597E-03 0,04804202 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 5,597E-03 0,04792925 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 5,597E-03 0,047817 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 5,597E-03 0,04770528 ! response to UV-C GO:0010225 15 5 0,000 5,597E-03 0,04759408 ! positive regulation of organ growth GO:0046622 5 5 0,000 5,597E-03 0,04748339 ! response to arsenic GO:0046685 6 5 0,000 5,597E-03 0,04737322 ! IgE binding GO:0019863 5 5 0,000 5,597E-03 0,04726356 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 5,597E-03 0,04715441 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 5,597E-03 0,04704576 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 5,597E-03 0,04693761 ! response to copper ion GO:0046688 5 5 0,000 5,597E-03 0,04682995 ! response to cadmium ion GO:0046686 5 5 0,000 5,597E-03 0,04672279 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 5,597E-03 0,04661612 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 5,597E-03 0,04650993 ! protein autoprocessing GO:0016540 6 5 0,000 5,597E-03 0,04640423 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 5,597E-03 0,046299 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 5,597E-03 0,04619425 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 5,597E-03 0,04608998 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 5,597E-03 0,04598617 ! mitotic recombination GO:0006312 15 5 0,000 5,597E-03 0,04588283 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 5,597E-03 0,04577995 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,597E-03 0,04567754 ! membrane to membrane docking GO:0022614 5 5 0,000 5,597E-03 0,04557558 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 5,597E-03 0,04547407 ! translation activator activity GO:0008494 5 5 0,000 5,597E-03 0,04537302 ! somatostatin receptor activity GO:0004994 5 5 0,000 5,597E-03 0,04527242 ! melanocortin receptor activity GO:0004977 6 5 0,000 5,597E-03 0,04517225 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 5,597E-03 0,04507254 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 5,597E-03 0,04497326 ! salivary gland morphogenesis GO:0007435 5 5 0,000 5,597E-03 0,04487442 ! galactosidase activity GO:0015925 5 5 0,000 5,597E-03 0,04477601 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 5,597E-03 0,04467803 ! cellular response to nutrient GO:0031670 5 5 0,000 5,597E-03 0,04458048 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 5,597E-03 0,04448335 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 5,597E-03 0,04438665 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 5,597E-03 0,04429037 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 5,597E-03 0,0441945 ! A band GO:0031672 5 5 0,000 5,597E-03 0,04409905 ! heat generation GO:0031649 5 5 0,000 5,597E-03 0,04400401 ! flagellum organization GO:0043064 5 5 0,000 5,597E-03 0,04390937 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 5,597E-03 0,04381515 ! disaccharide metabolic process GO:0005984 6 5 0,000 5,597E-03 0,04372133 ! glycogen catabolic process GO:0005980 16 5 0,000 5,597E-03 0,0436279 ! dopamine biosynthetic process GO:0042416 6 5 0,000 5,597E-03 0,04353488 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 5,597E-03 0,04344225 ! chromocenter GO:0010369 5 5 0,000 5,597E-03 0,04335002 ! glial cell migration GO:0008347 5 5 0,000 5,597E-03 0,04325818 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 5,597E-03 0,04316672 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 5,597E-03 0,04307565 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 5,597E-03 0,04298497 ! growth hormone receptor binding GO:0005131 5 5 0,000 5,597E-03 0,04289466 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 5,597E-03 0,04280474 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 5,597E-03 0,04271519 ! aminomethyltransferase activity GO:0004047 5 5 0,000 5,597E-03 0,04262601 ! aminoacylase activity GO:0004046 5 5 0,000 5,597E-03 0,04253721 ! penetration of zona pellucida GO:0007341 6 5 0,000 5,597E-03 0,04244877 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 5,597E-03 0,0423607 ! nucleus localization GO:0051647 5 5 0,000 5,597E-03 0,042273 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 5,597E-03 0,04218566 ! carnitine metabolic process GO:0009437 5 5 0,000 5,597E-03 0,04209868 GO:0006577|betaine metabolic process, ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,713E-03 0,05038755 ! regulation of helicase activity GO:0051095 6 6 0,000 6,713E-03 0,05028409 ! response to oxygen radical GO:0000305 6 6 0,000 6,713E-03 0,05018104 ! positive regulation of axon extension GO:0045773 7 6 0,000 6,713E-03 0,05007842 ! forebrain neuron differentiation GO:0021879 6 6 0,000 6,713E-03 0,04997622 ! forebrain regionalization GO:0021871 7 6 0,000 6,713E-03 0,04987444 ! meiotic prophase I GO:0007128 7 6 0,000 6,713E-03 0,04977307 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 6,713E-03 0,04967211 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 6,713E-03 0,04957156 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,713E-03 0,04947141 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 6,713E-03 0,04937167 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 6,713E-03 0,04927233 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 6,713E-03 0,04917339 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 6,713E-03 0,04907485 ! protein amino acid sulfation GO:0006477 9 6 0,000 6,713E-03 0,0489767 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 6,713E-03 0,04887894 ! establishment of tissue polarity GO:0007164 8 6 0,000 6,713E-03 0,04878157 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 6,713E-03 0,04868459 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 6,713E-03 0,048588 ! embryonic camera-type eye development GO:0031076 9 6 0,000 6,713E-03 0,04849178 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 6,713E-03 0,04839595 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 6,713E-03 0,04830049 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 6,713E-03 0,04820541 ! Notch receptor processing GO:0007220 7 6 0,000 6,713E-03 0,04811071 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 6,713E-03 0,04801637 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 6,713E-03 0,04792241 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 6,713E-03 0,04782881 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 6,713E-03 0,04773557 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 6,713E-03 0,0476427 ! neurofilament GO:0005883 7 6 0,000 6,713E-03 0,04755019 ! glial cell fate commitment GO:0021781 7 6 0,000 6,713E-03 0,04745804 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 6,713E-03 0,04736625 ! dynactin complex GO:0005869 7 6 0,000 6,713E-03 0,04727481 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 6,713E-03 0,04718372 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 6,713E-03 0,04709298 ! oocyte maturation GO:0001556 6 6 0,000 6,713E-03 0,04700259 ! DNA replication origin binding GO:0003688 6 6 0,000 6,713E-03 0,04691255 ! reflex GO:0060004 10 6 0,000 6,713E-03 0,04682285 ! positive regulation of glycolysis GO:0045821 6 6 0,000 6,713E-03 0,04673349 ! parathyroid gland development GO:0060017 6 6 0,000 6,713E-03 0,04664448 ! anagen GO:0042640 7 6 0,000 6,713E-03 0,0465558 ! protein-cofactor linkage GO:0018065 15 6 0,000 6,713E-03 0,04646746 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 6,713E-03 0,04637945 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 6,713E-03 0,04629178 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 6,713E-03 0,04620443 ! skeletal myofibril assembly GO:0014866 6 6 0,000 6,713E-03 0,04611742 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 6,713E-03 0,04603073 ! cysteine metabolic process GO:0006534 7 6 0,000 6,713E-03 0,04594437 ! glycine catabolic process GO:0006546 6 6 0,000 6,713E-03 0,04585833 ! adenohypophysis development GO:0021984 6 6 0,000 6,713E-03 0,04577262 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 6,713E-03 0,04568722 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 6,713E-03 0,04560214 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 6,713E-03 0,04551738 ! microtubule nucleation GO:0007020 7 6 0,000 6,713E-03 0,04543293 ! proline biosynthetic process GO:0006561 8 6 0,000 6,713E-03 0,0453488 ! tryptophan metabolic process GO:0006568 6 6 0,000 6,713E-03 0,04526497 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 6,713E-03 0,04518146 ! thyroid hormone generation GO:0006590 6 6 0,000 6,713E-03 0,04509825 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 6,713E-03 0,04501535 ! retinoid X receptor binding GO:0046965 7 6 0,000 6,713E-03 0,04493275 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 6,713E-03 0,04485046 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 6,713E-03 0,04476846 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,713E-03 0,04468677 ! sister chromatid cohesion GO:0007062 6 6 0,000 6,713E-03 0,04460537 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 6,713E-03 0,04452427 ! positive regulation of transporter activity GO:0032411 8 6 0,000 6,713E-03 0,04444347 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 6,713E-03 0,04436295 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 6,713E-03 0,04428273 ! p53 binding GO:0002039 6 6 0,000 6,713E-03 0,0442028 ! demethylase activity GO:0032451 6 6 0,000 6,713E-03 0,04412315 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 6,713E-03 0,04404379 ! regulation of platelet activation GO:0010543 7 6 0,000 6,713E-03 0,04396472 ! lipid phosphatase activity GO:0042577 7 6 0,000 6,713E-03 0,04388593 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 6,713E-03 0,04380742 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 6,713E-03 0,0437292 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 6,713E-03 0,04365125 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 6,713E-03 0,04357358 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 6,713E-03 0,04349618 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 6,713E-03 0,04341906 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 6,713E-03 0,04334221 ! LIM domain binding GO:0030274 7 6 0,000 6,713E-03 0,04326564 ! negative regulation of translational initiation GO:0045947 6 6 0,000 6,713E-03 0,04318933 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 6,713E-03 0,04311329 ! 5S class rRNA transcription GO:0042791 6 6 0,000 6,713E-03 0,04303752 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 6,713E-03 0,04296202 ! axon guidance receptor activity GO:0008046 6 6 0,000 6,713E-03 0,04288678 ! zinc ion homeostasis GO:0055069 7 6 0,000 6,713E-03 0,0428118 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 6,713E-03 0,04273708 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 6,713E-03 0,04266263 ! protein targeting to lysosome GO:0006622 6 6 0,000 6,713E-03 0,04258843 ! hyaluronan metabolic process GO:0030212 8 6 0,000 6,713E-03 0,0425145 ! protein retention in ER lumen GO:0006621 6 6 0,000 6,713E-03 0,04244081 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 6,713E-03 0,04236739 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 6,713E-03 0,04229421 ! dynein binding GO:0045502 6 6 0,000 6,713E-03 0,04222129 ! regulation of dendrite development GO:0050773 6 6 0,000 6,713E-03 0,04214862 ! peptidyl-arginine modification GO:0018195 6 6 0,000 6,713E-03 0,0420762 ! eating behavior GO:0042755 7 6 0,000 6,713E-03 0,04200403 ! protein localization to chromosome GO:0034502 8 6 0,000 6,713E-03 0,04193211 ! Hsp90 protein binding GO:0051879 7 6 0,000 6,713E-03 0,04186043 ! glycolipid binding GO:0051861 7 6 0,000 6,713E-03 0,04178899 ! MutLalpha complex binding GO:0032405 8 6 0,000 6,713E-03 0,0417178 ! mast cell activation GO:0045576 6 6 0,000 6,713E-03 0,04164685 ! regulation of focal adhesion formation GO:0051893 6 6 0,000 6,713E-03 0,04157615 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,713E-03 0,04150568 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 6,713E-03 0,04143545 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 6,713E-03 0,04136546 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 6,713E-03 0,0412957 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 6,713E-03 0,04122618 ! lipoxygenase activity GO:0016165 6 6 0,000 6,713E-03 0,04115689 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 6,713E-03 0,04108783 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 6,713E-03 0,04101901 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 6,713E-03 0,04095042 ! DNA replication factor C complex GO:0005663 7 6 0,000 6,713E-03 0,04088205 ! DNA replication factor A complex GO:0005662 7 6 0,000 6,713E-03 0,04081392 ! establishment of chromosome localization GO:0051303 15 6 0,000 6,713E-03 0,04074601 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 6,713E-03 0,04067832 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 6,713E-03 0,04061086 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 6,713E-03 0,04054362 ! chromatin assembly complex GO:0005678 16 6 0,000 6,713E-03 0,04047661 ! sex chromatin GO:0001739 6 6 0,000 6,713E-03 0,04040982 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 6,713E-03 0,04034324 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 6,713E-03 0,04027689 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 6,713E-03 0,04021075 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 6,713E-03 0,04014484 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 6,713E-03 0,04007913 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 6,713E-03 0,04001364 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 6,713E-03 0,03994837 ! phosphatidylserine binding GO:0001786 6 6 0,000 6,713E-03 0,03988331 ! alpha-mannosidase activity GO:0004559 8 6 0,000 6,713E-03 0,03981845 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 6,713E-03 0,03975381 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 6,713E-03 0,03968938 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 6,713E-03 0,03962516 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 6,713E-03 0,03956115 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 6,713E-03 0,03949734 ! leading edge membrane GO:0031256 8 6 0,000 6,713E-03 0,03943374 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 6,713E-03 0,03937034 ! CARD domain binding GO:0050700 6 6 0,000 6,713E-03 0,03930714 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 6,713E-03 0,03924415 ! COPII vesicle coat GO:0030127 7 6 0,000 6,713E-03 0,03918136 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 6,713E-03 0,03911877 ! glutathione biosynthetic process GO:0006750 7 6 0,000 6,713E-03 0,03905638 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 6,713E-03 0,03899419 ! positive regulation of epidermis development GO:0045684 8 6 0,000 6,713E-03 0,03893219 ! proteasome regulator activity GO:0010860 6 6 0,000 6,713E-03 0,0388704 ! ceramidase activity GO:0017040 6 6 0,000 6,713E-03 0,03880879 ! antibiotic transport GO:0042891 7 6 0,000 6,713E-03 0,03874739 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 6,713E-03 0,03868618 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 6,713E-03 0,03862516 ! sodium channel regulator activity GO:0017080 6 6 0,000 6,713E-03 0,03856433 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 6,713E-03 0,03850369 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 6,713E-03 0,03844325 ! response to fluid shear stress GO:0034405 6 6 0,000 6,713E-03 0,03838299 ! lymph node development GO:0048535 6 6 0,000 6,713E-03 0,03832293 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 6,713E-03 0,03826305 ! triglyceride catabolic process GO:0019433 15 6 0,000 6,713E-03 0,03820335 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 6,713E-03 0,03814385 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 6,713E-03 0,03808452 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 6,713E-03 0,03802539 ! negative regulation of lipase activity GO:0060192 6 6 0,000 6,713E-03 0,03796643 ! activation of innate immune response GO:0002218 6 6 0,000 6,713E-03 0,03790766 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 6,713E-03 0,03784907 ! sarcoglycan complex GO:0016012 8 6 0,000 6,713E-03 0,03779066 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 6,713E-03 0,03773243 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 6,713E-03 0,03767438 ! neural plate development GO:0001840 7 6 0,000 6,713E-03 0,03761651 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 6,713E-03 0,03755882 ! catecholamine transport GO:0051937 6 6 0,000 6,713E-03 0,0375013 ! ether hydrolase activity GO:0016803 7 6 0,000 6,713E-03 0,03744396 ! FACIT collagen GO:0005593 6 6 0,000 6,713E-03 0,03738679 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 6,713E-03 0,0373298 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 6,713E-03 0,03727298 ! collagen type IV GO:0005587 6 6 0,000 6,713E-03 0,03721634 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 6,713E-03 0,03715986 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 6,713E-03 0,03710356 ! drug metabolic process GO:0017144 6 6 0,000 6,713E-03 0,03704743 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 6,713E-03 0,03699146 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 6,713E-03 0,03693567 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 6,713E-03 0,03688004 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 6,713E-03 0,03682459 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 6,713E-03 0,03676929 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 6,713E-03 0,03671417 ! cellular anion homeostasis GO:0030002 6 6 0,000 6,713E-03 0,03665921 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 6,713E-03 0,03660441 ! negative regulation of protein ubiquitination GO:0031397 7 6 0,000 6,713E-03 0,03654978 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 6,713E-03 0,0364953 ! behavioral response to cocaine GO:0048148 9 6 0,000 6,713E-03 0,036441 ! translation initiation factor binding GO:0031369 6 6 0,000 6,713E-03 0,03638685 ! nucleotide-sugar transport GO:0015780 6 6 0,000 6,713E-03 0,03633286 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 6,713E-03 0,03627904 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 6,713E-03 0,03622537 ! quaternary ammonium group binding GO:0050997 7 6 0,000 6,713E-03 0,03617186 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 6,713E-03 0,03611851 ! reproductive behavior GO:0019098 8 6 0,000 6,713E-03 0,03606532 ! response to growth hormone stimulus GO:0060416 7 6 0,000 6,713E-03 0,03601228 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 6,713E-03 0,0359594 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 6,713E-03 0,03590667 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 6,713E-03 0,0358541 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 6,713E-03 0,03580168 ! induction of positive chemotaxis GO:0050930 7 6 0,000 6,713E-03 0,03574942 ! cohesin complex GO:0008278 6 6 0,000 6,713E-03 0,0356973 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 6,713E-03 0,03564534 ! citrate metabolic process GO:0006101 7 6 0,000 6,713E-03 0,03559353 ! myelin sheath GO:0043209 8 6 0,000 6,713E-03 0,03554187 ! phototransduction, visible light GO:0007603 6 6 0,000 6,713E-03 0,03549036 ! opsonization GO:0008228 7 6 0,000 6,713E-03 0,035439 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 6,713E-03 0,03538779 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 6,713E-03 0,03533672 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 6,713E-03 0,03528581 ! regulation of potassium ion transport GO:0043266 8 6 0,000 6,713E-03 0,03523504 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 6,713E-03 0,03518441 ! chemoattractant activity GO:0042056 6 6 0,000 6,713E-03 0,03513393 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 6,713E-03 0,0350836 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 6,713E-03 0,0350334 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 6,713E-03 0,03498336 ! leukocyte degranulation GO:0043299 6 6 0,000 6,713E-03 0,03493345 ! bile acid and bile salt transport GO:0015721 7 6 0,000 6,713E-03 0,03488369 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 6,713E-03 0,03483407 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 6,713E-03 0,03478459 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 6,713E-03 0,03473525 ! DNA topoisomerase activity GO:0003916 6 6 0,000 6,713E-03 0,03468605 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 6,713E-03 0,03463699 ! ceramide biosynthetic process GO:0046513 6 6 0,000 6,713E-03 0,03458806 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 6,713E-03 0,03453928 ! activin receptor activity GO:0017002 7 6 0,000 6,713E-03 0,03449063 ! astrocyte differentiation GO:0048708 6 6 0,000 6,713E-03 0,03444212 ! syncytium formation GO:0006949 6 6 0,000 6,713E-03 0,03439375 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 6,713E-03 0,03434551 ! neutrophil activation GO:0042119 6 6 0,000 6,713E-03 0,03429741 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 6,713E-03 0,03424944 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 6,713E-03 0,03420161 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 6,713E-03 0,0341539 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 6,713E-03 0,03410634 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 6,713E-03 0,0340589 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 6,713E-03 0,0340116 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 6,713E-03 0,03396442 ! neuron apoptosis GO:0051402 7 6 0,000 6,713E-03 0,03391738 ! folic acid transport GO:0015884 8 6 0,000 6,713E-03 0,03387047 ! carnitine transport GO:0015879 6 6 0,000 6,713E-03 0,03382369 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 6,713E-03 0,03377703 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 6,713E-03 0,03373051 ! S-methyltransferase activity GO:0008172 6 6 0,000 6,713E-03 0,03368411 ! phospholipase D activity GO:0004630 6 6 0,000 6,713E-03 0,03363784 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 6,713E-03 0,0335917 ! intercalated disc GO:0014704 8 6 0,000 6,713E-03 0,03354568 ! G2/M transition checkpoint GO:0031576 24 6 0,000 6,713E-03 0,03349979 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 6,713E-03 0,03345403 ! IgG binding GO:0019864 6 6 0,000 6,713E-03 0,03340839 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 6,713E-03 0,03336287 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 6,713E-03 0,03331748 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 6,713E-03 0,03327221 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 6,713E-03 0,03322707 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 6,713E-03 0,03318205 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 6,713E-03 0,03313714 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 6,713E-03 0,03309236 ! dendrite morphogenesis GO:0048813 7 6 0,000 6,713E-03 0,03304771 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 6,713E-03 0,03300317 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 6,713E-03 0,03295875 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 6,713E-03 0,03291445 ! nucleosome disassembly GO:0006337 7 6 0,000 6,713E-03 0,03287027 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 6,713E-03 0,03282621 ! regulation of mast cell activation GO:0033003 6 6 0,000 6,713E-03 0,03278226 ! tetracycline transporter activity GO:0008493 7 6 0,000 6,713E-03 0,03273844 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 6,713E-03 0,03269473 ! receptor internalization GO:0031623 8 6 0,000 6,713E-03 0,03265113 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 6,713E-03 0,03260766 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 6,713E-03 0,03256429 ! histamine receptor activity GO:0004969 7 6 0,000 6,713E-03 0,03252105 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 6,713E-03 0,03247792 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 6,713E-03 0,0324349 ! protein deubiquitination GO:0016579 6 6 0,000 6,713E-03 0,032392 ! axonal fasciculation GO:0007413 7 6 0,000 6,713E-03 0,03234921 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 6,713E-03 0,03230653 ! cytidine deaminase activity GO:0004126 6 6 0,000 6,713E-03 0,03226397 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 6,713E-03 0,03222151 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 6,713E-03 0,03217917 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 6,713E-03 0,03213694 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 6,713E-03 0,03209482 ! glycine binding GO:0016594 9 6 0,000 6,713E-03 0,03205281 ! apical protein localization GO:0045176 7 6 0,000 6,713E-03 0,03201091 ! ankyrin binding GO:0030506 6 6 0,000 6,713E-03 0,03196912 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 6,713E-03 0,03192744 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 6,713E-03 0,03188587 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 6,713E-03 0,03184441 ! progesterone metabolic process GO:0042448 6 6 0,000 6,713E-03 0,03180305 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 6,713E-03 0,0317618 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 6,713E-03 0,03172066 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 6,713E-03 0,03167962 ! ATP catabolic process GO:0006200 6 6 0,000 6,713E-03 0,03163869 ! CoA carboxylase activity GO:0016421 6 6 0,000 6,713E-03 0,03159787 ! determination of adult lifespan GO:0008340 6 6 0,000 6,713E-03 0,03155715 ! S-acyltransferase activity GO:0016417 6 6 0,000 6,713E-03 0,03151654 ! somatic stem cell maintenance GO:0035019 6 6 0,000 6,713E-03 0,03147603 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 6,713E-03 0,03143562 ! IkappaB kinase complex GO:0008385 7 6 0,000 6,713E-03 0,03139532 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 6,713E-03 0,03135512 ! store-operated calcium channel activity GO:0015279 6 6 0,000 6,713E-03 0,03131502 ! alkaline phosphatase activity GO:0004035 7 6 0,000 6,713E-03 0,03127503 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 6,713E-03 0,03123514 ! unconventional myosin complex GO:0016461 8 6 0,000 6,713E-03 0,03119535 ! tRNA transcription GO:0009304 7 7 0,000 7,827E-03 0,03632887 ! respiratory burst GO:0045730 7 7 0,000 7,827E-03 0,03628271 ! telencephalon cell migration GO:0022029 8 7 0,000 7,827E-03 0,03623666 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 7,827E-03 0,03619073 ! cation:chloride symporter activity GO:0015377 8 7 0,000 7,827E-03 0,03614492 ! RNA cap binding GO:0000339 8 7 0,000 7,827E-03 0,03609923 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 7,827E-03 0,03605365 ! ephrin receptor binding GO:0046875 9 7 0,000 7,827E-03 0,03600818 ! male meiosis I GO:0007141 7 7 0,000 7,827E-03 0,03596283 ! synapsis GO:0007129 7 7 0,000 7,827E-03 0,0359176 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 7,827E-03 0,03587247 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 7,827E-03 0,03582746 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 7,827E-03 0,03578257 ! signal peptide processing GO:0006465 7 7 0,000 7,827E-03 0,03573778 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 7,827E-03 0,03569311 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 7,827E-03 0,03564855 ! macrophage chemotaxis GO:0048246 7 7 0,000 7,827E-03 0,0356041 ! Golgi cisterna membrane GO:0032580 7 7 0,000 7,827E-03 0,03555976 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 7,827E-03 0,03551553 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 7,827E-03 0,03547142 ! smoothened signaling pathway GO:0007224 8 7 0,000 7,827E-03 0,03542741 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 7,827E-03 0,03538351 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 7,827E-03 0,03533971 ! cytoplasmic microtubule GO:0005881 7 7 0,000 7,827E-03 0,03529603 ! Arp2/3 protein complex GO:0005885 8 7 0,000 7,827E-03 0,03525246 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 7,827E-03 0,03520899 ! ATPase binding GO:0051117 8 7 0,000 7,827E-03 0,03516563 ! positive regulation of isotype switching GO:0045830 7 7 0,000 7,827E-03 0,03512237 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 7,827E-03 0,03507923 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 7,827E-03 0,03503618 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 7,827E-03 0,03499325 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,827E-03 0,03495042 ! thymic T cell selection GO:0045061 16 7 0,000 7,827E-03 0,03490769 ! transepithelial chloride transport GO:0030321 7 7 0,000 7,827E-03 0,03486507 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 7,827E-03 0,03482255 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 7,827E-03 0,03478013 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 7,827E-03 0,03473782 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 7,827E-03 0,03469561 ! melanocyte differentiation GO:0030318 8 7 0,000 7,827E-03 0,03465351 ! malate dehydrogenase activity GO:0016615 8 7 0,000 7,827E-03 0,0346115 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 7,827E-03 0,0345696 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 7,827E-03 0,0345278 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 7,827E-03 0,0344861 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 7,827E-03 0,0344445 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 7,827E-03 0,034403 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 7,827E-03 0,0343616 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 7,827E-03 0,0343203 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 7,827E-03 0,0342791 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 7,827E-03 0,034238 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 7,827E-03 0,03419699 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 7,827E-03 0,03415609 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 7,827E-03 0,03411528 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 7,827E-03 0,03407457 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 7,827E-03 0,03403396 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 7,827E-03 0,03399344 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 7,827E-03 0,03395302 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 7,827E-03 0,0339127 ! melanosome organization GO:0032438 7 7 0,000 7,827E-03 0,03387247 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 7,827E-03 0,03383233 ! mesodermal cell differentiation GO:0048333 9 7 0,000 7,827E-03 0,0337923 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 7,827E-03 0,03375235 ! Rac protein signal transduction GO:0016601 7 7 0,000 7,827E-03 0,0337125 ! chondrocyte differentiation GO:0002062 7 7 0,000 7,827E-03 0,03367275 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 7,827E-03 0,03363309 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 7,827E-03 0,03359352 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 7,827E-03 0,03355404 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 7,827E-03 0,03351466 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 7,827E-03 0,03347537 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 7,827E-03 0,03343617 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 7,827E-03 0,03339706 ! Schwann cell differentiation GO:0014037 8 7 0,000 7,827E-03 0,03335805 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 7,827E-03 0,03331912 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 7,827E-03 0,03328029 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 7,827E-03 0,03324155 ! vinculin binding GO:0017166 9 7 0,000 7,827E-03 0,03320289 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 7,827E-03 0,03316433 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 7,827E-03 0,03312586 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 7,827E-03 0,03308747 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 7,827E-03 0,03304918 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 7,827E-03 0,03301097 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 7,827E-03 0,03297285 ! cardiac muscle cell development GO:0055013 8 7 0,000 7,827E-03 0,03293482 ! fibrinolysis GO:0042730 9 7 0,000 7,827E-03 0,03289688 ! response to tropane GO:0014073 10 7 0,000 7,827E-03 0,03285902 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 7,827E-03 0,03282125 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 7,827E-03 0,03278357 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 7,827E-03 0,03274597 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 7,827E-03 0,03270846 ! laminin-1 complex GO:0005606 7 7 0,000 7,827E-03 0,03267104 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 7,827E-03 0,0326337 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 7,827E-03 0,03259645 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 7,827E-03 0,03255928 ! regulation of cell division GO:0051302 7 7 0,000 7,827E-03 0,0325222 ! holo TFIIH complex GO:0005675 7 7 0,000 7,827E-03 0,0324852 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 7,827E-03 0,03244828 ! chitinase activity GO:0004568 7 7 0,000 7,827E-03 0,03241145 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 7,827E-03 0,0323747 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 7,827E-03 0,03233804 ! regulation of respiratory burst GO:0060263 8 7 0,000 7,827E-03 0,03230146 ! prophase GO:0051324 8 7 0,000 7,827E-03 0,03226496 ! peptidyl-histidine modification GO:0018202 8 7 0,000 7,827E-03 0,03222854 ! centriolar satellite GO:0034451 10 7 0,000 7,827E-03 0,03219221 ! BBSome GO:0034464 7 7 0,000 7,827E-03 0,03215596 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 7,827E-03 0,03211979 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,827E-03 0,0320837 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 7,827E-03 0,03204769 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 7,827E-03 0,03201176 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 7,827E-03 0,03197591 ! regulation of synaptogenesis GO:0051963 7 7 0,000 7,827E-03 0,03194014 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 7,827E-03 0,03190446 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 7,827E-03 0,03186885 ! glycolipid catabolic process GO:0019377 7 7 0,000 7,827E-03 0,03183332 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 7,827E-03 0,03179787 ! circadian behavior GO:0048512 9 7 0,000 7,827E-03 0,0317625 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 7,827E-03 0,03172721 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 7,827E-03 0,031692 ! striatum development GO:0021756 7 7 0,000 7,827E-03 0,03165686 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 7,827E-03 0,0316218 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 7,827E-03 0,03158682 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 7,827E-03 0,03155192 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 7,827E-03 0,0315171 ! dystroglycan complex GO:0016011 9 7 0,000 7,827E-03 0,03148235 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 7,827E-03 0,03144768 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 7,827E-03 0,03141308 ! peroxiredoxin activity GO:0051920 7 7 0,000 7,827E-03 0,03137856 ! muscle adaptation GO:0043500 7 7 0,000 7,827E-03 0,03134412 ! regulation of muscle adaptation GO:0043502 7 7 0,000 7,827E-03 0,03130975 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 7,827E-03 0,03127545 ! lysogeny GO:0030069 7 7 0,000 7,827E-03 0,03124124 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 7,827E-03 0,03120709 ! sequestering of metal ion GO:0051238 9 7 0,000 7,827E-03 0,03117302 ! membrane attack complex GO:0005579 7 7 0,000 7,827E-03 0,03113903 ! fibrinogen complex GO:0005577 7 7 0,000 7,827E-03 0,03110511 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 7,827E-03 0,03107126 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 7,827E-03 0,03103749 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 7,827E-03 0,03100379 ! GABA receptor binding GO:0050811 8 7 0,000 7,827E-03 0,03097016 ! sheet-forming collagen GO:0030935 7 7 0,000 7,827E-03 0,03093661 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 7,827E-03 0,03090313 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 7,827E-03 0,03086972 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 7,827E-03 0,03083638 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 7,827E-03 0,03080312 ! 7S RNA binding GO:0008312 8 7 0,000 7,827E-03 0,03076992 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 7,827E-03 0,0307368 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 7,827E-03 0,03070375 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 7,827E-03 0,03067077 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 7,827E-03 0,03063786 ! Golgi to endosome transport GO:0006895 8 7 0,000 7,827E-03 0,03060503 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 7,827E-03 0,03057226 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 7,827E-03 0,03053956 ! fibril GO:0043205 7 7 0,000 7,827E-03 0,03050693 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 7,827E-03 0,03047438 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 7,827E-03 0,03044189 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 7,827E-03 0,03040947 ! sensory perception of bitter taste GO:0050913 7 7 0,000 7,827E-03 0,03037712 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 7,827E-03 0,03034483 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 7,827E-03 0,03031262 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 7,827E-03 0,03028048 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 7,827E-03 0,0302484 ! equilibrioception GO:0050957 10 7 0,000 7,827E-03 0,03021639 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 7,827E-03 0,03018445 ! titin binding GO:0031432 7 7 0,000 7,827E-03 0,03015258 ! chemosensory behavior GO:0007635 9 7 0,000 7,827E-03 0,03012077 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 7,827E-03 0,03008903 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 7,827E-03 0,03005736 ! cobalamin binding GO:0031419 7 7 0,000 7,827E-03 0,03002575 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 7,827E-03 0,02999421 ! response to axon injury GO:0048678 9 7 0,000 7,827E-03 0,02996274 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 7,827E-03 0,02993133 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 7,827E-03 0,02989999 ! F-actin capping protein complex GO:0008290 8 7 0,000 7,827E-03 0,02986871 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 7,827E-03 0,0298375 ! cGMP-mediated signaling GO:0019934 8 7 0,000 7,827E-03 0,02980636 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 7,827E-03 0,02977528 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 7,827E-03 0,02974426 ! senescence GO:0010149 8 7 0,000 7,827E-03 0,02971331 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 7,827E-03 0,02968242 ! nuclear localization sequence binding GO:0008139 8 7 0,000 7,827E-03 0,0296516 ! galactose metabolic process GO:0006012 8 7 0,000 7,827E-03 0,02962084 ! vesicle fusion GO:0006906 8 7 0,000 7,827E-03 0,02959014 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 7,827E-03 0,02955951 ! intracellular pH reduction GO:0051452 7 7 0,000 7,827E-03 0,02952894 ! glycerol ether catabolic process GO:0044269 16 7 0,000 7,827E-03 0,02949844 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 7,827E-03 0,029468 ! ruffle organization GO:0031529 9 7 0,000 7,827E-03 0,02943762 ! nucleoside transport GO:0015858 8 7 0,000 7,827E-03 0,0294073 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 7,827E-03 0,02937705 ! inclusion body GO:0016234 7 7 0,000 7,827E-03 0,02934685 ! Cajal body GO:0015030 7 7 0,000 7,827E-03 0,02931672 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 7,827E-03 0,02928666 ! rRNA modification GO:0000154 7 7 0,000 7,827E-03 0,02925665 ! PcG protein complex GO:0031519 7 7 0,000 7,827E-03 0,0292267 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 7,827E-03 0,02919682 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 7,827E-03 0,029167 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 7,827E-03 0,02913723 ! apolipoprotein binding GO:0034185 9 7 0,000 7,827E-03 0,02910753 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 7,827E-03 0,02907789 ! segment specification GO:0007379 9 7 0,000 7,827E-03 0,02904831 ! pronucleus GO:0045120 25 7 0,000 7,827E-03 0,02901879 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 7,827E-03 0,02898933 ! Rac GTPase activator activity GO:0030675 9 7 0,000 7,827E-03 0,02895993 ! regulation of DNA repair GO:0006282 19 7 0,000 7,827E-03 0,02893059 ! preribosome GO:0030684 7 7 0,000 7,827E-03 0,02890131 ! DNA topological change GO:0006265 7 7 0,000 7,827E-03 0,02887208 ! DNA ligation GO:0006266 8 7 0,000 7,827E-03 0,02884292 ! hair follicle maturation GO:0048820 8 7 0,000 7,827E-03 0,02881381 ! renal water homeostasis GO:0003091 7 7 0,000 7,827E-03 0,02878477 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 7,827E-03 0,02875578 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 7,827E-03 0,02872685 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 7,827E-03 0,02869798 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 7,827E-03 0,02866917 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 7,827E-03 0,02864041 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 7,827E-03 0,02861171 ! phosphofructokinase activity GO:0008443 7 7 0,000 7,827E-03 0,02858307 ! gap junction channel activity GO:0005243 8 7 0,000 7,827E-03 0,02855449 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 7,827E-03 0,02852596 ! histone methylation GO:0016571 7 7 0,000 7,827E-03 0,02849749 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 7,827E-03 0,02846908 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 7,827E-03 0,02844073 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 7,827E-03 0,02841243 ! muscle cell proliferation GO:0033002 8 7 0,000 7,827E-03 0,02838418 ! transcription termination GO:0006353 9 7 0,000 7,827E-03 0,028356 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 0,000 7,827E-03 0,02832787 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 7,827E-03 0,02829979 ! cytidylyltransferase activity GO:0070567 8 7 0,000 7,827E-03 0,02827177 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 7,827E-03 0,02824381 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 7,827E-03 0,0282159 ! salivary gland development GO:0007431 7 7 0,000 7,827E-03 0,02818804 ! glucosidase activity GO:0015926 8 7 0,000 7,827E-03 0,02816025 ! NuRD complex GO:0016581 8 7 0,000 7,827E-03 0,0281325 ! negative regulation of nuclear division GO:0051784 7 7 0,000 7,827E-03 0,02810481 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 7,827E-03 0,02807718 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 7,827E-03 0,0280496 ! response to redox state GO:0051775 8 7 0,000 7,827E-03 0,02802207 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 7,827E-03 0,0279946 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 7,827E-03 0,02796718 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 7,827E-03 0,02793981 ! actin monomer binding GO:0003785 7 7 0,000 7,827E-03 0,0279125 ! protein prenyltransferase activity GO:0008318 8 7 0,000 7,827E-03 0,02788524 ! endosome to lysosome transport GO:0008333 7 7 0,000 7,827E-03 0,02785804 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 7,827E-03 0,02783089 ! germ cell migration GO:0008354 7 7 0,000 7,827E-03 0,02780379 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 7,827E-03 0,02777674 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 7,827E-03 0,02774975 ! CoA-ligase activity GO:0016405 8 7 0,000 7,827E-03 0,02772281 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 7,827E-03 0,02769592 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 7,827E-03 0,02766908 ! embryonic heart tube development GO:0035050 8 7 0,000 7,827E-03 0,02764229 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 7,827E-03 0,02761556 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 7,827E-03 0,02758888 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 7,827E-03 0,02756225 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 7,827E-03 0,02753567 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 7,827E-03 0,02750914 ! adenylate kinase activity GO:0004017 8 7 0,000 7,827E-03 0,02748267 ! negative regulation of immune effector process GO:0002698 13 7 0,000 7,827E-03 0,02745624 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 7,827E-03 0,02742987 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 7,827E-03 0,02740354 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 8,941E-03 0,0312716 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 8,941E-03 0,03124165 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 8,941E-03 0,03121175 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 8,941E-03 0,03118192 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 0,000 8,941E-03 0,03115213 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 8,941E-03 0,03112241 ! SMAD protein complex assembly GO:0007183 10 8 0,000 8,941E-03 0,03109274 ! regulation of smooth muscle cell migration GO:0014910 11 8 0,000 8,941E-03 0,03106313 ! protein self-association GO:0043621 8 8 0,000 8,941E-03 0,03103357 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 8,941E-03 0,03100407 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 8,941E-03 0,03097463 ! neurotransmitter uptake GO:0001504 8 8 0,000 8,941E-03 0,03094524 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 8,941E-03 0,03091591 ! guanylate cyclase activity GO:0004383 9 8 0,000 8,941E-03 0,03088663 ! troponin complex GO:0005861 8 8 0,000 8,941E-03 0,03085741 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 8,941E-03 0,03082825 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 8,941E-03 0,03079913 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 8,941E-03 0,03077008 ! microtubule bundle formation GO:0001578 8 8 0,000 8,941E-03 0,03074108 ! middle ear morphogenesis GO:0042474 10 8 0,000 8,941E-03 0,03071213 ! ganglioside metabolic process GO:0001573 8 8 0,000 8,941E-03 0,03068324 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 8,941E-03 0,0306544 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 8,941E-03 0,03062562 ! ciliary or flagellar motility GO:0001539 8 8 0,000 8,941E-03 0,03059689 ! pathogenesis GO:0009405 8 8 0,000 8,941E-03 0,03056821 ! pH reduction GO:0045851 9 8 0,000 8,941E-03 0,03053959 ! small protein activating enzyme activity GO:0008641 10 8 0,000 8,941E-03 0,03051102 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 8,941E-03 0,03048251 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 8,941E-03 0,03045405 ! hemoglobin metabolic process GO:0020027 8 8 0,000 8,941E-03 0,03042564 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 8,941E-03 0,03039728 ! arginine catabolic process GO:0006527 9 8 0,000 8,941E-03 0,03036898 ! T-tubule GO:0030315 9 8 0,000 8,941E-03 0,03034073 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 8,941E-03 0,03031253 ! histidine catabolic process GO:0006548 8 8 0,000 8,941E-03 0,03028439 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 8,941E-03 0,03025629 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 8,941E-03 0,03022825 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 8,941E-03 0,03020026 ! proline metabolic process GO:0006560 10 8 0,000 8,941E-03 0,03017233 ! L-serine metabolic process GO:0006563 9 8 0,000 8,941E-03 0,03014444 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 8,941E-03 0,03011661 ! melanosome membrane GO:0033162 9 8 0,000 8,941E-03 0,03008882 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 8,941E-03 0,03006109 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 8,941E-03 0,03003341 ! pericentriolar material GO:0000242 9 8 0,000 8,941E-03 0,03000578 ! reverse cholesterol transport GO:0043691 8 8 0,000 8,941E-03 0,0299782 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 8,941E-03 0,02995067 ! melanin metabolic process GO:0006582 10 8 0,000 8,941E-03 0,0299232 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 8,941E-03 0,02989577 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 8,941E-03 0,02986839 ! Golgi lumen GO:0005796 8 8 0,000 8,941E-03 0,02984106 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 8,941E-03 0,02981379 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 8,941E-03 0,02978656 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 8,941E-03 0,02975938 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 8,941E-03 0,02973226 ! stereocilium bundle GO:0032421 11 8 0,000 8,941E-03 0,02970518 ! forebrain cell migration GO:0021885 9 8 0,000 8,941E-03 0,02967815 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 8,941E-03 0,02965117 ! osteoblast development GO:0002076 11 8 0,000 8,941E-03 0,02962424 ! retinoic acid metabolic process GO:0042573 8 8 0,000 8,941E-03 0,02959735 ! retinol metabolic process GO:0042572 8 8 0,000 8,941E-03 0,02957052 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 8,941E-03 0,02954374 ! structural constituent of epidermis GO:0030280 9 8 0,000 8,941E-03 0,029517 ! clathrin binding GO:0030276 10 8 0,000 8,941E-03 0,02949031 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 8,941E-03 0,02946367 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 8,941E-03 0,02943708 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 8,941E-03 0,02941054 ! motor axon guidance GO:0008045 8 8 0,000 8,941E-03 0,02938404 ! protein targeting to vacuole GO:0006623 8 8 0,000 8,941E-03 0,02935759 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 8,941E-03 0,02933119 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 8,941E-03 0,02930484 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 8,941E-03 0,02927853 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 8,941E-03 0,02925227 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 8,941E-03 0,02922606 ! protein-lipid complex assembly GO:0065005 8 8 0,000 8,941E-03 0,0291999 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 8,941E-03 0,02917378 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 8,941E-03 0,02914771 ! regulation of dopamine secretion GO:0014059 9 8 0,000 8,941E-03 0,02912168 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 8,941E-03 0,0290957 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 8,941E-03 0,02906977 ! subpallium development GO:0021544 8 8 0,000 8,941E-03 0,02904389 ! positive regulation of Rho GTPase activity GO:0032321 11 8 0,000 8,941E-03 0,02901805 ! icosanoid secretion GO:0032309 10 8 0,000 8,941E-03 0,02899225 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 8,941E-03 0,0289665 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 8,941E-03 0,0289408 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 8,941E-03 0,02891515 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 8,941E-03 0,02888953 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 8,941E-03 0,02886397 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 8,941E-03 0,02883845 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 8,941E-03 0,02881297 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 8,941E-03 0,02878754 ! ubiquinone metabolic process GO:0006743 9 8 0,000 8,941E-03 0,02876216 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 8,941E-03 0,02873681 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 8,941E-03 0,02871152 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 8,941E-03 0,02868627 ! Wnt receptor activity GO:0042813 11 8 0,000 8,941E-03 0,02866106 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 8,941E-03 0,02863589 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 8,941E-03 0,02861078 ! detection of calcium ion GO:0005513 9 8 0,000 8,941E-03 0,0285857 ! negative regulation of glucose import GO:0046325 9 8 0,000 8,941E-03 0,02856067 ! blastocyst growth GO:0001832 8 8 0,000 8,941E-03 0,02853568 ! regulation of fibrinolysis GO:0051917 8 8 0,000 8,941E-03 0,02851074 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 8,941E-03 0,02848584 ! cerebellar cortex formation GO:0021697 9 8 0,000 8,941E-03 0,02846098 ! complement binding GO:0001848 11 8 0,000 8,941E-03 0,02843617 ! regulation of actin filament bundle formation GO:0032231 13 8 0,000 8,941E-03 0,0284114 GO:0051492|regulation of stress fiber formation, ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 8,941E-03 0,02838667 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 8,941E-03 0,02836199 ! amino sugar catabolic process GO:0046348 8 8 0,000 8,941E-03 0,02833734 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 8,941E-03 0,02831275 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 8,941E-03 0,02828819 ! positive regulation of amine transport GO:0051954 9 8 0,000 8,941E-03 0,02826368 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 8,941E-03 0,02823921 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 8,941E-03 0,02821478 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 8,941E-03 0,02819039 ! Golgi transport complex GO:0017119 8 8 0,000 8,941E-03 0,02816605 ! positive regulation of protein ubiquitination GO:0031398 17 8 0,000 8,941E-03 0,02814175 ! GDP binding GO:0019003 9 8 0,000 8,941E-03 0,02811749 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 8,941E-03 0,02809327 ! prostate gland development GO:0030850 17 8 0,000 8,941E-03 0,02806909 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 8,941E-03 0,02804496 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 8,941E-03 0,02802086 ! phosphate transport GO:0006817 9 8 0,000 8,941E-03 0,02799681 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 8,941E-03 0,0279728 ! oligopeptide transport GO:0006857 8 8 0,000 8,941E-03 0,02794883 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 8,941E-03 0,0279249 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 8,941E-03 0,02790101 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 8,941E-03 0,02787717 ! lipoprotein transport GO:0042953 9 8 0,000 8,941E-03 0,02785336 ! estrogen metabolic process GO:0008210 8 8 0,000 8,941E-03 0,02782959 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 8,941E-03 0,02780587 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 8,941E-03 0,02778218 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 8,941E-03 0,02775854 ! T-helper 1 type immune response GO:0042088 8 8 0,000 8,941E-03 0,02773494 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 8,941E-03 0,02771137 ! response to amphetamine GO:0001975 11 8 0,000 8,941E-03 0,02768785 ! mechanosensory behavior GO:0007638 8 8 0,000 8,941E-03 0,02766436 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 8,941E-03 0,02764092 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 8,941E-03 0,02761751 ! C-X-C chemokine binding GO:0019958 8 8 0,000 8,941E-03 0,02759415 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 8,941E-03 0,02757082 ! glycerolipid catabolic process GO:0046503 17 8 0,000 8,941E-03 0,02754754 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 8,941E-03 0,02752429 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 8,941E-03 0,02750108 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 8,941E-03 0,02747791 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 8,941E-03 0,02745478 ! pigment granule organization GO:0048753 9 8 0,000 8,941E-03 0,02743169 ! GTP-dependent protein binding GO:0030742 11 8 0,000 8,941E-03 0,02740864 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 8,941E-03 0,02738563 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 8,941E-03 0,02736265 ! regulation of pigmentation during development GO:0048070 11 8 0,000 8,941E-03 0,02733972 ! macrophage activation GO:0042116 8 8 0,000 8,941E-03 0,02731682 ! poly(A) RNA binding GO:0008143 8 8 0,000 8,941E-03 0,02729396 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 8,941E-03 0,02727114 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 8,941E-03 0,02724836 ! asymmetric protein localization GO:0008105 9 8 0,000 8,941E-03 0,02722561 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 8,941E-03 0,02720291 ! neurotrophin binding GO:0043121 10 8 0,000 8,941E-03 0,02718024 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 8,941E-03 0,02715761 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 8,941E-03 0,02713501 ! phagocytosis, engulfment GO:0006911 10 8 0,000 8,941E-03 0,02711246 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 8,941E-03 0,02708994 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 8,941E-03 0,02706746 ! UV protection GO:0009650 9 8 0,000 8,941E-03 0,02704501 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 8,941E-03 0,0270226 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 8,941E-03 0,02700023 ! glutathione peroxidase activity GO:0004602 17 8 0,000 8,941E-03 0,0269779 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 8,941E-03 0,02695561 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 8,941E-03 0,02693335 ! ferric iron binding GO:0008199 9 8 0,000 8,941E-03 0,02691113 ! response to UV-B GO:0010224 10 8 0,000 8,941E-03 0,02688894 ! intermediate filament organization GO:0045109 8 8 0,000 8,941E-03 0,02686679 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 8,941E-03 0,02684468 ! cellular extravasation GO:0045123 9 8 0,000 8,941E-03 0,0268226 ! skeletal muscle contraction GO:0003009 8 8 0,000 8,941E-03 0,02680056 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 8,941E-03 0,02677856 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 0,000 8,941E-03 0,02675659 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 8,941E-03 0,02673466 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 8,941E-03 0,02671276 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 8,941E-03 0,0266909 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 8,941E-03 0,02666908 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 8,941E-03 0,02664729 ! erythrocyte development GO:0048821 9 8 0,000 8,941E-03 0,02662554 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 8,941E-03 0,02660382 ! ribosome assembly GO:0042255 8 8 0,000 8,941E-03 0,02658214 ! postreplication repair GO:0006301 19 8 0,000 8,941E-03 0,02656049 ! gamma-tubulin binding GO:0043015 8 8 0,000 8,941E-03 0,02653888 ! NADPH oxidase complex GO:0043020 8 8 0,000 8,941E-03 0,0265173 ! mRNA cleavage GO:0006379 9 8 0,000 8,941E-03 0,02649576 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 8,941E-03 0,02647426 ! opioid receptor activity GO:0004985 8 8 0,000 8,941E-03 0,02645278 ! zymogen activation GO:0031638 9 8 0,000 8,941E-03 0,02643135 ! coenzyme A metabolic process GO:0015936 8 8 0,000 8,941E-03 0,02640995 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 8,941E-03 0,02638858 ! costamere GO:0043034 8 8 0,000 8,941E-03 0,02636725 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 8,941E-03 0,02634595 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 8,941E-03 0,02632468 ! sarcomere organization GO:0045214 9 8 0,000 8,941E-03 0,02630345 ! wide pore channel activity GO:0022829 9 8 0,000 8,941E-03 0,02628226 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 8,941E-03 0,0262611 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 8,941E-03 0,02623997 ! hormone catabolic process GO:0042447 9 8 0,000 8,941E-03 0,02621888 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 8,941E-03 0,02619782 ! cGMP biosynthetic process GO:0006182 9 8 0,000 8,941E-03 0,02617679 ! lysozyme activity GO:0003796 10 8 0,000 8,941E-03 0,0261558 ! death receptor binding GO:0005123 8 8 0,000 8,941E-03 0,02613484 ! protein modification by small protein removal GO:0070646 9 8 0,000 8,941E-03 0,02611392 ! adult feeding behavior GO:0008343 9 8 0,000 8,941E-03 0,02609303 ! microtubule basal body GO:0005932 8 8 0,000 8,941E-03 0,02607217 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 8,941E-03 0,02605134 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 8,941E-03 0,02603055 ! calcium-release channel activity GO:0015278 8 8 0,000 8,941E-03 0,0260098 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 8,941E-03 0,02598907 ! behavioral response to nicotine GO:0035095 9 8 0,000 8,941E-03 0,02596838 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 8,941E-03 0,02594772 ! adenosine deaminase activity GO:0004000 8 8 0,000 8,941E-03 0,02592709 ! NAD biosynthetic process GO:0009435 9 8 0,000 8,941E-03 0,0259065 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 0,01005311 0,02910614 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 0,01005311 0,02908306 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 0,01005311 0,02906001 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 0,01005311 0,029037 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 0,01005311 0,02901403 ! myotube differentiation GO:0014902 9 9 0,000 0,01005311 0,0289911 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 0,01005311 0,0289682 ! N-glycan processing GO:0006491 10 9 0,000 0,01005311 0,02894533 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 0,01005311 0,02892251 ! actin-myosin filament sliding GO:0033275 11 9 0,000 0,01005311 0,02889971 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 0,01005311 0,02887696 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 0,01005311 0,02885424 ! RNA methylation GO:0001510 9 9 0,000 0,01005311 0,02883155 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 0,01005311 0,02880891 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 0,01005311 0,02878629 ! artery development GO:0060840 9 9 0,000 0,01005311 0,02876372 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 0,01005311 0,02874117 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 0,01005311 0,02871867 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 0,01005311 0,02869619 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 0,01005311 0,02867376 ! positive regulation of heart contraction GO:0045823 11 9 0,000 0,01005311 0,02865136 ! lipopolysaccharide binding GO:0001530 9 9 0,000 0,01005311 0,02862899 ! regulated secretory pathway GO:0045055 10 9 0,000 0,01005311 0,02860666 ! estrogen receptor binding GO:0030331 9 9 0,000 0,01005311 0,02858436 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 0,01005311 0,0285621 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 0,01005311 0,02853987 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 0,01005311 0,02851768 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 0,01005311 0,02849552 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 0,000 0,01005311 0,0284734 ! urea metabolic process GO:0019627 19 9 0,000 0,01005311 0,02845131 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 0,01005311 0,02842925 ! autophagic vacuole GO:0005776 11 9 0,000 0,01005311 0,02840723 ! Rac GTPase binding GO:0048365 10 9 0,000 0,01005311 0,02838525 ! response to dietary excess GO:0002021 9 9 0,000 0,01005311 0,02836329 ! regulation of sodium ion transport GO:0002028 10 9 0,000 0,01005311 0,02834137 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01005311 0,02831949 ! lens development in camera-type eye GO:0002088 9 9 0,000 0,01005311 0,02829764 ! male sex determination GO:0030238 9 9 0,000 0,01005311 0,02827582 ! positive regulation of vasodilation GO:0045909 19 9 0,000 0,01005311 0,02825403 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 0,01005311 0,02823228 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 0,01005311 0,02821057 ! male germ cell nucleus GO:0001673 11 9 0,000 0,01005311 0,02818888 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 0,01005311 0,02816723 ! copper ion homeostasis GO:0055070 9 9 0,000 0,01005311 0,02814562 ! protein heterooligomerization GO:0051291 10 9 0,000 0,01005311 0,02812403 ! spectrin GO:0008091 9 9 0,000 0,01005311 0,02810248 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 0,01005311 0,02808096 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 0,01005311 0,02805948 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 0,01005311 0,02803802 ! regulation of B cell differentiation GO:0045577 10 9 0,000 0,01005311 0,02801661 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 0,01005311 0,02799522 ! neural tube patterning GO:0021532 10 9 0,000 0,01005311 0,02797386 ! fucose catabolic process GO:0019317 10 9 0,000 0,01005311 0,02795254 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 0,01005311 0,02793125 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 0,01005311 0,02791 ! sterol catabolic process GO:0016127 10 9 0,000 0,01005311 0,02788877 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 0,01005311 0,02786758 ! clathrin coat of coated pit GO:0030132 11 9 0,000 0,01005311 0,02784642 ! SNARE complex GO:0031201 11 9 0,000 0,01005311 0,02782529 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 0,01005311 0,0278042 ! negative regulation of glucose transport GO:0010829 10 9 0,000 0,01005311 0,02778313 ! methionine biosynthetic process GO:0009086 11 9 0,000 0,01005311 0,0277621 ! peptidoglycan binding GO:0042834 9 9 0,000 0,01005311 0,0277411 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 0,01005311 0,02772013 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 0,01005311 0,0276992 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 0,01005311 0,02767829 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 0,01005311 0,02765742 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 0,01005311 0,02763658 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 0,01005311 0,02761577 ! detection of bacterium GO:0016045 10 9 0,000 0,01005311 0,02759499 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 0,01005311 0,02757424 ! embryonic gut development GO:0048566 10 9 0,000 0,01005311 0,02755352 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 0,01005311 0,02753284 ! desmosome GO:0030057 10 9 0,000 0,01005311 0,02751218 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 0,01005311 0,02749156 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 0,01005311 0,02747096 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 0,01005311 0,0274504 ! actin filament polymerization GO:0030041 10 9 0,000 0,01005311 0,02742987 ! negative regulation of B cell activation GO:0050869 10 9 0,000 0,01005311 0,02740937 ! establishment of cell polarity GO:0030010 10 9 0,000 0,01005311 0,0273889 ! regulation of synapse organization GO:0050807 10 9 0,000 0,01005311 0,02736846 ! septin complex GO:0031105 10 9 0,000 0,01005311 0,02734805 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 0,01005311 0,02732767 ! anchoring collagen GO:0030934 9 9 0,000 0,01005311 0,02730732 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 0,01005311 0,02728701 ! regulation of developmental growth GO:0048638 11 9 0,000 0,01005311 0,02726672 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 0,01005311 0,02724646 ! GMP binding GO:0019002 11 9 0,000 0,01005311 0,02722623 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 0,01005311 0,02720604 ! virus-host interaction GO:0019048 13 9 0,000 0,01005311 0,02718587 ! pentose-phosphate shunt GO:0006098 11 9 0,000 0,01005311 0,02716573 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 0,01005311 0,02714562 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 0,01005311 0,02712554 ! non-recombinational repair GO:0000726 10 9 0,000 0,01005311 0,0271055 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 0,01005311 0,02708548 ! nuclear telomere cap complex GO:0000783 10 9 0,000 0,01005311 0,02706549 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 0,01005311 0,02704553 ! social behavior GO:0035176 10 9 0,000 0,01005311 0,0270256 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 0,01005311 0,0270057 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 0,01005311 0,02698583 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 0,01005311 0,02696598 ! mating GO:0007618 11 9 0,000 0,01005311 0,02694617 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 0,01005311 0,02692639 ! rhythmic behavior GO:0007622 11 9 0,000 0,01005311 0,02690663 ! phospholipid efflux GO:0033700 10 9 0,000 0,01005311 0,0268869 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 0,01005311 0,02686721 ! poly-purine tract binding GO:0070717 9 9 0,000 0,01005311 0,02684754 ! T cell proliferation GO:0042098 10 9 0,000 0,01005311 0,0268279 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 0,01005311 0,02680829 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 0,01005311 0,0267887 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 0,01005311 0,02676915 ! interleukin-1 binding GO:0019966 10 9 0,000 0,01005311 0,02674963 ! glucosyltransferase activity GO:0046527 9 9 0,000 0,01005311 0,02673013 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 0,01005311 0,02671066 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 0,01005311 0,02669122 ! ovulation GO:0030728 9 9 0,000 0,01005311 0,02667181 ! acid phosphatase activity GO:0003993 18 9 0,000 0,01005311 0,02665242 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 0,01005311 0,02663307 ! ER overload response GO:0006983 11 9 0,000 0,01005311 0,02661374 ! B cell proliferation GO:0042100 10 9 0,000 0,01005311 0,02659444 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 0,01005311 0,02657517 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 0,01005311 0,02655593 ! mannose metabolic process GO:0006013 13 9 0,000 0,01005311 0,02653671 ! lipid digestion GO:0044241 11 9 0,000 0,01005311 0,02651752 ! tumor necrosis factor binding GO:0043120 9 9 0,000 0,01005311 0,02649836 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 0,01005311 0,02647923 ! regulation of bone resorption GO:0045124 10 9 0,000 0,01005311 0,02646013 ! brain morphogenesis GO:0048854 9 9 0,000 0,01005311 0,02644105 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 0,01005311 0,026422 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 0,01005311 0,02640298 ! synaptic vesicle membrane GO:0030672 9 9 0,000 0,01005311 0,02638398 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 0,01005311 0,02636502 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 0,01005311 0,02634608 ! kinesin binding GO:0019894 9 9 0,000 0,01005311 0,02632716 ! multicellular organismal aging GO:0010259 18 9 0,000 0,01005311 0,02630828 ! Ran GTPase binding GO:0008536 11 9 0,000 0,01005311 0,02628942 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 0,01005311 0,02627058 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 0,01005311 0,02625178 ! mRNA polyadenylation GO:0006378 10 9 0,000 0,01005311 0,026233 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 0,01005311 0,02621425 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 0,01005311 0,02619553 ! prostaglandin receptor activity GO:0004955 11 9 0,000 0,01005311 0,02617683 ! caspase inhibitor activity GO:0043027 9 9 0,000 0,01005311 0,02615816 ! adrenoceptor activity GO:0004935 12 9 0,000 0,01005311 0,02613951 ! regulation of isotype switching GO:0045191 9 9 0,000 0,01005311 0,0261209 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 0,01005311 0,0261023 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 0,01005311 0,02608374 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 0,01005311 0,0260652 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 0,01005311 0,02604669 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 0,01005311 0,0260282 ! Notch binding GO:0005112 10 9 0,000 0,01005311 0,02600974 ! ATPase regulator activity GO:0060590 10 9 0,000 0,01005311 0,02599131 ! gamma-tubulin complex GO:0000930 19 9 0,000 0,01005311 0,0259729 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 0,01005311 0,02595452 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 0,01005311 0,02593616 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 0,01005311 0,02591784 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 0,01005311 0,02589953 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,01116416 0,0287416 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,01116416 0,02872133 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,01116416 0,02870109 ! sleep GO:0030431 11 10 0,000 0,01116416 0,02868088 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,01116416 0,0286607 ! lipid particle GO:0005811 10 10 0,000 0,01116416 0,02864054 ! filopodium assembly GO:0046847 14 10 0,000 0,01116416 0,02862042 ! UTP metabolic process GO:0046051 12 10 0,000 0,01116416 0,02860032 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,01116416 0,02858025 ! guanylate kinase activity GO:0004385 14 10 0,000 0,01116416 0,02856021 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,01116416 0,02854019 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,01116416 0,0285202 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,01116416 0,02850025 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,01116416 0,02848032 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,01116416 0,02846041 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,01116416 0,02844054 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,01116416 0,02842069 ! lung alveolus development GO:0048286 11 10 0,000 0,01116416 0,02840087 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,01116416 0,02838108 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01116416 0,02836132 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,01116416 0,02834158 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,01116416 0,02832187 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,01116416 0,02830219 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,01116416 0,02828254 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,01116416 0,02826291 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,01116416 0,02824331 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,01116416 0,02822374 ! histidine metabolic process GO:0006547 10 10 0,000 0,01116416 0,02820419 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,01116416 0,02818467 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,01116416 0,02816518 ! death receptor activity GO:0005035 11 10 0,000 0,01116416 0,02814572 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,01116416 0,02812628 ! entry into host cell GO:0030260 11 10 0,000 0,01116416 0,02810687 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,01116416 0,02808748 ! filamentous actin GO:0031941 11 10 0,000 0,01116416 0,02806813 ! behavioral fear response GO:0001662 12 10 0,000 0,01116416 0,0280488 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,01116416 0,02802949 ! negative regulation of ossification GO:0030279 12 10 0,000 0,01116416 0,02801021 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,01116416 0,02799096 ! macrophage differentiation GO:0030225 11 10 0,000 0,01116416 0,02797174 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,01116416 0,02795254 ! recycling endosome membrane GO:0055038 11 10 0,000 0,01116416 0,02793337 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,01116416 0,02791422 ! snRNA metabolic process GO:0016073 10 10 0,000 0,01116416 0,0278951 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,01116416 0,02787601 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 0,01116416 0,02785694 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,01116416 0,0278379 ! positive regulation of Ras GTPase activity GO:0032320 14 10 0,000 0,01116416 0,02781889 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,01116416 0,0277999 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,01116416 0,02778094 ! induction of an organ GO:0001759 12 10 0,000 0,01116416 0,027762 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,01116416 0,02774309 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,01116416 0,0277242 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,01116416 0,02770534 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,01116416 0,02768651 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,01116416 0,0276677 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,01116416 0,02764892 ! ribonuclease P activity GO:0004526 10 10 0,000 0,01116416 0,02763016 ! COPI vesicle coat GO:0030126 12 10 0,000 0,01116416 0,02761143 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,01116416 0,02759272 ! vitamin transporter activity GO:0051183 12 10 0,000 0,01116416 0,02757404 ! snRNA binding GO:0017069 11 10 0,000 0,01116416 0,02755538 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,01116416 0,02753675 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,01116416 0,02751814 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,01116416 0,02749956 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,01116416 0,02748101 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,01116416 0,02746248 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,01116416 0,02744397 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,01116416 0,02742549 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,01116416 0,02740703 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,01116416 0,0273886 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,01116416 0,0273702 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 0,01116416 0,02735182 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 0,01116416 0,02733346 ! extracellular matrix binding GO:0050840 11 10 0,000 0,01116416 0,02731513 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,01116416 0,02729682 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,01116416 0,02727853 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,01116416 0,02726028 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,01116416 0,02724204 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 0,01116416 0,02722383 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,01116416 0,02720565 ! thyroid gland development GO:0030878 12 10 0,000 0,01116416 0,02718749 ! DNA bending activity GO:0008301 11 10 0,000 0,01116416 0,02716935 ! regulation of phosphatase activity GO:0010921 10 10 0,000 0,01116416 0,02715124 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,01116416 0,02713315 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,01116416 0,02711508 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,01116416 0,02709704 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,01116416 0,02707902 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,01116416 0,02706103 ! regulation of glycolysis GO:0006110 11 10 0,000 0,01116416 0,02704306 ! nucleotidase activity GO:0008252 10 10 0,000 0,01116416 0,02702512 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,01116416 0,0270072 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,01116416 0,0269893 ! androgen metabolic process GO:0008209 11 10 0,000 0,01116416 0,02697143 ! lateral plasma membrane GO:0016328 13 10 0,000 0,01116416 0,02695358 ! MAP kinase kinase activity GO:0004708 12 10 0,000 0,01116416 0,02693575 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,01116416 0,02691795 ! startle response GO:0001964 13 10 0,000 0,01116416 0,02690017 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,01116416 0,02688241 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,01116416 0,02686468 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 0,01116416 0,02684697 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,01116416 0,02682928 ! spinal cord patterning GO:0021511 12 10 0,000 0,01116416 0,02681162 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,01116416 0,02679398 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,01116416 0,02677637 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,01116416 0,02675877 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 0,01116416 0,0267412 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,01116416 0,02672366 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,01116416 0,02670613 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,01116416 0,02668863 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,01116416 0,02667115 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,01116416 0,0266537 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,01116416 0,02663627 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,01116416 0,02661886 ! adult heart development GO:0007512 14 10 0,000 0,01116416 0,02660147 ! neuromuscular junction development GO:0007528 12 10 0,000 0,01116416 0,02658411 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,01116416 0,02656677 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,01116416 0,02654945 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,01116416 0,02653215 ! signalosome GO:0008180 10 10 0,000 0,01116416 0,02651488 ! lysophospholipase activity GO:0004622 19 10 0,000 0,01116416 0,02649763 ! prefoldin complex GO:0016272 10 10 0,000 0,01116416 0,0264804 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,01116416 0,02646319 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,01116416 0,02644601 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,01116416 0,02642885 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,01116416 0,02641171 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,01116416 0,02639459 ! gland morphogenesis GO:0022612 11 10 0,000 0,01116416 0,0263775 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,01116416 0,02636042 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,01116416 0,02634337 ! peptide transporter activity GO:0015197 10 10 0,000 0,01116416 0,02632634 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,01116416 0,02630934 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,01116416 0,02629235 ! muscle maintenance GO:0046716 10 10 0,000 0,01116416 0,02627539 ! acid secretion GO:0046717 12 10 0,000 0,01116416 0,02625845 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,01116416 0,02624153 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,01116416 0,02622463 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,01116416 0,02620776 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,01116416 0,0261909 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,01116416 0,02617407 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,01116416 0,02615726 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,01116416 0,02614047 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,01116416 0,0261237 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 0,01116416 0,02610696 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,01116416 0,02609023 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,01116416 0,02607353 ! water channel activity GO:0015250 15 10 0,000 0,01116416 0,02605685 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,01116416 0,02604019 ! regulation of embryonic development GO:0045995 12 10 0,000 0,01116416 0,02602355 ! acrosome reaction GO:0007340 12 10 0,000 0,01116416 0,02600693 ! mitochondrion localization GO:0051646 10 10 0,000 0,01116416 0,02599033 ! cilium part GO:0044441 10 10 0,000 0,01116416 0,02597376 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,01227402 0,02853769 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,01227402 0,02851951 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,01227402 0,02850136 ! centriole GO:0005814 11 11 0,000 0,01227402 0,02848323 ! cadmium ion binding GO:0046870 15 11 0,000 0,01227402 0,02846512 ! hemoglobin complex GO:0005833 13 11 0,000 0,01227402 0,02844704 ! CTP metabolic process GO:0046036 13 11 0,000 0,01227402 0,02842898 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,01227402 0,02841094 ! response to pain GO:0048265 12 11 0,000 0,01227402 0,02839292 ! regulation of viral genome replication GO:0045069 13 11 0,000 0,01227402 0,02837493 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,01227402 0,02835696 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,01227402 0,02833901 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,01227402 0,02832109 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,01227402 0,02830318 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01227402 0,0282853 ! peptide antigen binding GO:0042605 14 11 0,000 0,01227402 0,02826745 ! polyamine metabolic process GO:0006595 11 11 0,000 0,01227402 0,02824961 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,01227402 0,0282318 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,01227402 0,02821401 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,01227402 0,02819624 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,01227402 0,0281785 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,01227402 0,02816078 ! protein homotetramerization GO:0051289 13 11 0,000 0,01227402 0,02814308 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,01227402 0,0281254 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,01227402 0,02810774 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,01227402 0,02809011 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,01227402 0,0280725 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,01227402 0,02805491 ! response to dsRNA GO:0043331 21 11 0,000 0,01227402 0,02803734 ! response to amine stimulus GO:0014075 15 11 0,000 0,01227402 0,0280198 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,01227402 0,02800227 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,01227402 0,02798477 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,01227402 0,02796729 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,01227402 0,02794984 ! retinal binding GO:0016918 11 11 0,000 0,01227402 0,0279324 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,01227402 0,02791498 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,01227402 0,02789759 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,01227402 0,02788022 ! autonomic nervous system development GO:0048483 12 11 0,000 0,01227402 0,02786287 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,01227402 0,02784554 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,01227402 0,02782824 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,01227402 0,02781095 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,01227402 0,02779369 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,01227402 0,02777645 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,01227402 0,02775923 ! regulation of epidermis development GO:0045682 14 11 0,000 0,01227402 0,02774203 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,01227402 0,02772485 ! midbrain development GO:0030901 12 11 0,000 0,01227402 0,0277077 ! musculoskeletal movement GO:0050881 12 11 0,000 0,01227402 0,02769056 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 0,01227402 0,02767345 ! regulation of RNA stability GO:0043487 13 11 0,000 0,01227402 0,02765635 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,01227402 0,02763928 ! cell killing GO:0001906 13 11 0,000 0,01227402 0,02762223 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,01227402 0,0276052 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,01227402 0,02758819 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,01227402 0,0275712 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 0,01227402 0,02755424 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 0,01227402 0,02753729 ! folic acid binding GO:0005542 12 11 0,000 0,01227402 0,02752037 ! mRNA 3'-end processing GO:0031124 12 11 0,000 0,01227402 0,02750346 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,01227402 0,02748658 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,01227402 0,02746972 ! microspike assembly GO:0030035 15 11 0,000 0,01227402 0,02745287 ! lamellipodium assembly GO:0030032 22 11 0,000 0,01227402 0,02743605 ! fibrillar collagen GO:0005583 12 11 0,000 0,01227402 0,02741925 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,01227402 0,02740247 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,01227402 0,02738571 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,01227402 0,02736897 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,01227402 0,02735225 ! synaptonemal complex GO:0000795 11 11 0,000 0,01227402 0,02733555 ! reproductive cellular process GO:0048610 13 11 0,000 0,01227402 0,02731887 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,01227402 0,02730222 ! Golgi vesicle budding GO:0048194 12 11 0,000 0,01227402 0,02728558 ! response to cAMP GO:0051591 11 11 0,000 0,01227402 0,02726896 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,01227402 0,02725237 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,01227402 0,02723579 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01227402 0,02721923 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,01227402 0,02720269 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,01227402 0,02718618 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,01227402 0,02716968 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 0,01227402 0,02715321 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,01227402 0,02713675 ! drug transport GO:0015893 12 11 0,000 0,01227402 0,02712031 ! FMN binding GO:0010181 12 11 0,000 0,01227402 0,0271039 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,01227402 0,0270875 ! water transporter activity GO:0005372 17 11 0,000 0,01227402 0,02707112 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,01227402 0,02705476 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01227402 0,02703843 ! multicellular organism growth GO:0035264 12 11 0,000 0,01227402 0,02702211 ! integrator complex GO:0032039 11 11 0,000 0,01227402 0,02700581 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,01227402 0,02698953 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,01227402 0,02697327 ! brush border membrane GO:0031526 12 11 0,000 0,01227402 0,02695704 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,01227402 0,02694082 ! macroautophagy GO:0016236 12 11 0,000 0,01227402 0,02692462 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,01227402 0,02690844 ! neuromuscular junction GO:0031594 12 11 0,000 0,01227402 0,02689227 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,01227402 0,02687613 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 0,01227402 0,02686001 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,01227402 0,02684391 ! response to antibiotic GO:0046677 13 11 0,000 0,01227402 0,02682782 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,01227402 0,02681176 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,01227402 0,02679571 ! neuroblast proliferation GO:0007405 13 11 0,000 0,01227402 0,02677969 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,01227402 0,02676368 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,01227402 0,02674769 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,01227402 0,02673172 ! protein kinase C binding GO:0005080 11 11 0,000 0,01227402 0,02671577 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,01227402 0,02669984 ! male genitalia development GO:0030539 15 11 0,000 0,01227402 0,02668393 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,01227402 0,02666804 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,01227402 0,02665216 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,01227402 0,02663631 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,01227402 0,02662047 ! arylsulfatase activity GO:0004065 12 11 0,000 0,01227402 0,02660466 ! sterol transporter activity GO:0015248 11 11 0,000 0,01227402 0,02658886 ! response to nicotine GO:0035094 13 11 0,000 0,01227402 0,02657308 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01227402 0,02655732 ! rRNA transcription GO:0009303 12 12 0,000 0,0133827 0,028939 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,0133827 0,02892185 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,0133827 0,02890473 ! superoxide anion generation GO:0042554 12 12 0,000 0,0133827 0,02888763 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,0133827 0,02887054 ! regulation of S phase GO:0033261 16 12 0,000 0,0133827 0,02885348 ! regulation of chemokine production GO:0032642 13 12 0,000 0,0133827 0,02883644 ! male meiosis GO:0007140 12 12 0,000 0,0133827 0,02881942 ! signal complex assembly GO:0007172 15 12 0,000 0,0133827 0,02880241 ! positive regulation of GTPase activity GO:0043547 17 12 0,000 0,0133827 0,02878543 ! GTP metabolic process GO:0046039 14 12 0,000 0,0133827 0,02876847 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,0133827 0,02875153 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,0133827 0,0287346 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,0133827 0,0287177 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,0133827 0,02870082 ! cartilage condensation GO:0001502 14 12 0,000 0,0133827 0,02868395 ! polysome GO:0005844 14 12 0,000 0,0133827 0,02866711 ! hippocampus development GO:0021766 13 12 0,000 0,0133827 0,02865029 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,0133827 0,02863348 ! beta-amyloid binding GO:0001540 12 12 0,000 0,0133827 0,0286167 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,0133827 0,02859994 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,0133827 0,02858319 ! chylomicron GO:0042627 13 12 0,000 0,0133827 0,02856647 ! T cell selection GO:0045058 22 12 0,000 0,0133827 0,02854976 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,0133827 0,02853307 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,0133827 0,02851641 ! WW domain binding GO:0050699 12 12 0,000 0,0133827 0,02849976 ! methionine metabolic process GO:0006555 14 12 0,000 0,0133827 0,02848313 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,0133827 0,02846653 ! glycine metabolic process GO:0006544 14 12 0,000 0,0133827 0,02844994 ! plasma membrane organization GO:0007009 12 12 0,000 0,0133827 0,02843337 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,0133827 0,02841682 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,0133827 0,02840029 ! Golgi organization GO:0007030 15 12 0,000 0,0133827 0,02838377 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,0133827 0,02836728 ! mitotic spindle organization GO:0007052 13 12 0,000 0,0133827 0,02835081 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,0133827 0,02833435 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,0133827 0,02831792 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,0133827 0,0283015 ! temperature homeostasis GO:0001659 13 12 0,000 0,0133827 0,0282851 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,0133827 0,02826873 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,0133827 0,02825237 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,0133827 0,02823603 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,0133827 0,02821971 ! axon cargo transport GO:0008088 13 12 0,000 0,0133827 0,0282034 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,0133827 0,02818712 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,0133827 0,02817085 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,0133827 0,02815461 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,0133827 0,02813838 ! basal lamina GO:0005605 12 12 0,000 0,0133827 0,02812217 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,0133827 0,02810598 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,0133827 0,02808981 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,0133827 0,02807366 ! biomineral formation GO:0031214 14 12 0,000 0,0133827 0,02805752 ! water homeostasis GO:0030104 12 12 0,000 0,0133827 0,02804141 ! promoter binding GO:0010843 14 12 0,000 0,0133827 0,02802531 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,0133827 0,02800923 ! intestinal absorption GO:0050892 14 12 0,000 0,0133827 0,02799317 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,0133827 0,02797713 ! oocyte differentiation GO:0009994 13 12 0,000 0,0133827 0,02796111 ! oxygen transport GO:0015671 13 12 0,000 0,0133827 0,0279451 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,0133827 0,02792911 ! cholesterol efflux GO:0033344 13 12 0,000 0,0133827 0,02791315 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,0133827 0,02789719 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,0133827 0,02788126 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,0133827 0,02786535 ! tropomyosin binding GO:0005523 12 12 0,000 0,0133827 0,02784945 ! blastocyst formation GO:0001825 13 12 0,000 0,0133827 0,02783358 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,0133827 0,02781772 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,0133827 0,02780187 ! mannose binding GO:0005537 13 12 0,000 0,0133827 0,02778605 ! phosphoprotein binding GO:0051219 14 12 0,000 0,0133827 0,02777025 ! defense response to fungus GO:0050832 12 12 0,000 0,0133827 0,02775446 ! embryonic placenta development GO:0001892 16 12 0,000 0,0133827 0,02773869 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,0133827 0,02772294 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,0133827 0,0277072 ! acyl-CoA binding GO:0000062 12 12 0,000 0,0133827 0,02769149 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,0133827 0,02767579 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,0133827 0,02766011 ! copper ion transport GO:0006825 12 12 0,000 0,0133827 0,02764445 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,0133827 0,0276288 ! inositol metabolic process GO:0006020 21 12 0,000 0,0133827 0,02761317 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,0133827 0,02759756 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,0133827 0,02758197 ! protein complex disassembly GO:0043241 15 12 0,000 0,0133827 0,0275664 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,0133827 0,02755084 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,0133827 0,0275353 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,0133827 0,02751978 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,0133827 0,02750428 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,0133827 0,02748879 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,0133827 0,02747332 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,0133827 0,02745787 ! endoderm development GO:0007492 13 12 0,000 0,0133827 0,02744243 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,0133827 0,02742702 ! focal adhesion formation GO:0048041 16 12 0,000 0,0133827 0,02741162 ! T cell receptor complex GO:0042101 31 12 0,000 0,0133827 0,02739624 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,0133827 0,02738087 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,0133827 0,02736552 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,0133827 0,02735019 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,0133827 0,02733488 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,0133827 0,02731958 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,0133827 0,0273043 ! retinol binding GO:0019841 12 12 0,000 0,0133827 0,02728904 ! regulation of organ growth GO:0046620 12 12 0,000 0,0133827 0,02727379 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,0133827 0,02725857 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,0133827 0,02724335 ! histone acetylation GO:0016573 13 12 0,000 0,0133827 0,02722816 ! ribosome binding GO:0043022 13 12 0,000 0,0133827 0,02721298 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,0133827 0,02719782 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,0133827 0,02718268 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,0133827 0,02716755 ! tissue regeneration GO:0042246 12 12 0,000 0,0133827 0,02715244 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,0133827 0,02713735 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,0133827 0,02712227 ! germ cell nucleus GO:0043073 14 12 0,000 0,0133827 0,02710721 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,0133827 0,02709217 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,0133827 0,02707714 ! hexosaminidase activity GO:0015929 12 12 0,000 0,0133827 0,02706213 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,0133827 0,02704714 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,0133827 0,02703217 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,0133827 0,02701721 ! dopamine metabolic process GO:0042417 15 12 0,000 0,0133827 0,02700226 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,0133827 0,02698734 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,0133827 0,02697243 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,0133827 0,02695753 ! bacterial binding GO:0008367 14 12 0,000 0,0133827 0,02694266 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,0133827 0,02692779 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,0133827 0,02691295 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,0133827 0,02689812 ! localization within membrane GO:0051668 13 12 0,000 0,0133827 0,02688331 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,0133827 0,02686851 ! axoneme part GO:0044447 12 12 0,000 0,0133827 0,02685374 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01449019 0,02906005 ! neuron maturation GO:0042551 14 13 0,000 0,01449019 0,02904408 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01449019 0,02902813 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01449019 0,0290122 ! bone remodeling GO:0046849 14 13 0,000 0,01449019 0,02899628 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01449019 0,02898039 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01449019 0,02896451 ! striated muscle thin filament GO:0005865 14 13 0,000 0,01449019 0,02894864 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01449019 0,0289328 ! organelle fusion GO:0048284 16 13 0,000 0,01449019 0,02891697 ! palate development GO:0060021 15 13 0,000 0,01449019 0,02890116 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01449019 0,02888537 ! arginine metabolic process GO:0006525 14 13 0,000 0,01449019 0,02886959 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01449019 0,02885383 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01449019 0,02883809 ! response to retinoic acid GO:0032526 17 13 0,000 0,01449019 0,02882237 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01449019 0,02880666 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01449019 0,02879097 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01449019 0,0287753 ! fear response GO:0042596 15 13 0,000 0,01449019 0,02875964 ! epithelial cell development GO:0002064 22 13 0,000 0,01449019 0,028744 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,01449019 0,02872838 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01449019 0,02871278 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01449019 0,02869719 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01449019 0,02868162 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01449019 0,02866606 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01449019 0,02865053 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,01449019 0,02863501 ! cranial nerve development GO:0021545 15 13 0,000 0,01449019 0,0286195 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,01449019 0,02860402 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01449019 0,02858855 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,01449019 0,02857309 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01449019 0,02855766 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01449019 0,02854224 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01449019 0,02852683 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01449019 0,02851145 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01449019 0,02849608 ! NADP metabolic process GO:0006739 15 13 0,000 0,01449019 0,02848072 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01449019 0,02846539 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01449019 0,02845007 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01449019 0,02843476 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01449019 0,02841947 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01449019 0,0284042 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01449019 0,02838895 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01449019 0,02837371 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01449019 0,02835849 ! ADP binding GO:0043531 15 13 0,000 0,01449019 0,02834328 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01449019 0,02832809 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01449019 0,02831292 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01449019 0,02829776 ! neuron fate specification GO:0048665 25 13 0,000 0,01449019 0,02828262 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01449019 0,0282675 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01449019 0,02825239 ! water transport GO:0006833 18 13 0,000 0,01449019 0,0282373 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01449019 0,02822222 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01449019 0,02820716 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01449019 0,02819212 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01449019 0,02817709 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01449019 0,02816208 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,01449019 0,02814708 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01449019 0,0281321 ! myoblast differentiation GO:0045445 15 13 0,000 0,01449019 0,02811714 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01449019 0,02810219 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01449019 0,02808726 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01449019 0,02807234 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01449019 0,02805744 GO:0000155|two-component sensor activity, ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01449019 0,02804256 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01449019 0,02802769 ! exocrine system development GO:0035272 14 13 0,000 0,01449019 0,02801284 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01449019 0,027998 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01449019 0,02798318 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01449019 0,02796837 ! L-glutamate transport GO:0015813 14 13 0,000 0,01449019 0,02795358 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01449019 0,02793881 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01449019 0,02792405 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01449019 0,0279093 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01449019 0,02789458 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01449019 0,02787986 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,01449019 0,02786517 ! genitalia development GO:0048806 18 13 0,000 0,01449019 0,02785049 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01449019 0,02783582 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01449019 0,02782117 ! MHC class I protein binding GO:0042288 23 13 0,000 0,01449019 0,02780653 ! histone deacetylation GO:0016575 14 13 0,000 0,01449019 0,02779192 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01449019 0,02777731 ! DNA methylation GO:0006306 15 13 0,000 0,01449019 0,02776272 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01449019 0,02774815 ! chromatin silencing GO:0006342 13 13 0,000 0,01449019 0,02773359 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01449019 0,02771905 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01449019 0,02770452 ! T cell homeostasis GO:0043029 14 13 0,000 0,01449019 0,02769001 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01449019 0,02767551 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01449019 0,02766103 ! response to gamma radiation GO:0010332 14 13 0,000 0,01449019 0,02764656 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01449019 0,02763211 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01449019 0,02761767 ! purine base metabolic process GO:0006144 15 13 0,000 0,01449019 0,02760325 ! cAMP binding GO:0030552 15 13 0,000 0,01449019 0,02758884 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01449019 0,02757445 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01449019 0,02756007 ! regulation of axon extension GO:0030516 16 13 0,000 0,01449019 0,02754571 ! drug transporter activity GO:0015238 14 13 0,000 0,01449019 0,02753137 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01449019 0,02751703 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01449019 0,02750272 ! response to cold GO:0009409 13 13 0,000 0,01449019 0,02748842 ! cadherin binding GO:0045296 16 13 0,000 0,01449019 0,02747413 ! nucleolar part GO:0044452 13 13 0,000 0,01449019 0,02745986 ! tRNA modification GO:0006400 14 14 0,000 0,0155965 0,02954104 ! cis-Golgi network GO:0005801 16 14 0,000 0,0155965 0,02952571 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,0155965 0,02951039 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,0155965 0,02949509 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,0155965 0,02947981 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,0155965 0,02946454 ! peroxisomal transport GO:0043574 14 14 0,000 0,0155965 0,02944929 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,0155965 0,02943406 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,0155965 0,02941884 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,0155965 0,02940364 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,0155965 0,02938845 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,0155965 0,02937328 ! caspase activator activity GO:0008656 16 14 0,000 0,0155965 0,02935812 ! MHC class II protein complex GO:0042613 19 14 0,000 0,0155965 0,02934298 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,0155965 0,02932785 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,0155965 0,02931274 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,0155965 0,02929765 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,0155965 0,02928257 ! protein polyubiquitination GO:0000209 15 14 0,000 0,0155965 0,02926751 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,0155965 0,02925246 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,0155965 0,02923743 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,0155965 0,02922241 ! response to vitamin A GO:0033189 18 14 0,000 0,0155965 0,02920741 ! actin filament bundle formation GO:0051017 16 14 0,000 0,0155965 0,02919242 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,0155965 0,02917745 ! plasma membrane fusion GO:0045026 15 14 0,000 0,0155965 0,0291625 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,0155965 0,02914756 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,0155965 0,02913263 ! protein export from nucleus GO:0006611 14 14 0,000 0,0155965 0,02911772 ! presynaptic membrane GO:0042734 14 14 0,000 0,0155965 0,02910283 ! negative regulation of immune response GO:0050777 21 14 0,000 0,0155965 0,02908795 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,0155965 0,02907309 ! neural crest cell migration GO:0001755 15 14 0,000 0,0155965 0,02905824 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,0155965 0,02904341 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,0155965 0,02902859 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,0155965 0,02901379 ! cofactor transport GO:0051181 16 14 0,000 0,0155965 0,028999 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,0155965 0,02898423 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,0155965 0,02896947 ! cobalt ion binding GO:0050897 14 14 0,000 0,0155965 0,02895472 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,0155965 0,02894 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,0155965 0,02892528 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,0155965 0,02891059 ! gas transport GO:0015669 15 14 0,000 0,0155965 0,0288959 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,0155965 0,02888124 ! heme biosynthetic process GO:0006783 14 14 0,000 0,0155965 0,02886658 ! cerebellar cortex development GO:0021695 16 14 0,000 0,0155965 0,02885194 ! insulin secretion GO:0030073 17 14 0,000 0,0155965 0,02883732 ! tRNA binding GO:0000049 16 14 0,000 0,0155965 0,02882271 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,0155965 0,02880812 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,0155965 0,02879354 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,0155965 0,02877898 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,0155965 0,02876443 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,0155965 0,02874989 ! MAP kinase activity GO:0004707 16 14 0,000 0,0155965 0,02873537 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,0155965 0,02872087 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,0155965 0,02870637 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,0155965 0,0286919 ! C-C chemokine binding GO:0019957 15 14 0,000 0,0155965 0,02867744 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,0155965 0,02866299 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,0155965 0,02864856 ! response to osmotic stress GO:0006970 17 14 0,000 0,0155965 0,02863414 ! fructose metabolic process GO:0006000 15 14 0,000 0,0155965 0,02861974 ! telomeric DNA binding GO:0042162 17 14 0,000 0,0155965 0,02860535 ! monoamine transport GO:0015844 15 14 0,000 0,0155965 0,02859097 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,0155965 0,02857661 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,0155965 0,02856227 ! dendritic spine GO:0043197 15 14 0,000 0,0155965 0,02854793 ! stem cell development GO:0048864 14 14 0,000 0,0155965 0,02853362 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,0155965 0,02851932 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,0155965 0,02850503 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,0155965 0,02849075 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,0155965 0,02847649 ! regulation of cellular pH GO:0030641 14 14 0,000 0,0155965 0,02846225 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,0155965 0,02844802 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,0155965 0,0284338 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,0155965 0,0284196 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,0155965 0,02840541 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,0155965 0,02839123 ! mannosidase activity GO:0015923 19 14 0,000 0,0155965 0,02837707 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,0155965 0,02836293 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,0155965 0,0283488 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,0155965 0,02833468 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,0155965 0,02832057 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,0155965 0,02830648 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,0155965 0,02829241 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,0155965 0,02827835 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,0155965 0,0282643 ! sperm-egg recognition GO:0035036 17 14 0,000 0,0155965 0,02825027 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,0155965 0,02823625 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,0155965 0,02822224 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,0155965 0,02820825 ! positive regulation of translation GO:0045727 17 15 0,000 0,01670163 0,03019204 ! nuclear replication fork GO:0043596 26 15 0,000 0,01670163 0,03017708 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,01670163 0,03016214 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,01670163 0,03014722 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,01670163 0,03013231 ! endothelial cell migration GO:0043542 16 15 0,000 0,01670163 0,03011742 ! lipid phosphorylation GO:0046834 19 15 0,000 0,01670163 0,03010254 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01670163 0,03008767 ! response to vitamin GO:0033273 19 15 0,000 0,01670163 0,03007282 ! gene silencing by RNA GO:0031047 17 15 0,000 0,01670163 0,03005798 ! striated muscle thick filament GO:0005863 16 15 0,000 0,01670163 0,03004316 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,01670163 0,03002835 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,01670163 0,03001356 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,01670163 0,02999878 ! glutamate metabolic process GO:0006536 17 15 0,000 0,01670163 0,02998402 ! pituitary gland development GO:0021983 16 15 0,000 0,01670163 0,02996927 ! cholesterol binding GO:0015485 15 15 0,000 0,01670163 0,02995454 ! NAD metabolic process GO:0019674 17 15 0,000 0,01670163 0,02993982 ! protease binding GO:0002020 20 15 0,000 0,01670163 0,02992511 ! regulation of heart rate GO:0002027 20 15 0,000 0,01670163 0,02991042 ! actin filament bundle GO:0032432 18 15 0,000 0,01670163 0,02989575 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,01670163 0,02988108 ! regulation of exocytosis GO:0017157 16 15 0,000 0,01670163 0,02986644 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01670163 0,0298518 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,01670163 0,02983718 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,01670163 0,02982258 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,01670163 0,02980799 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,01670163 0,02979341 ! neuron recognition GO:0008038 18 15 0,000 0,01670163 0,02977885 ! regulation of Rho GTPase activity GO:0032319 18 15 0,000 0,01670163 0,0297643 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,01670163 0,02974977 ! filopodium GO:0030175 17 15 0,000 0,01670163 0,02973525 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,01670163 0,02972075 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,01670163 0,02970626 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,01670163 0,02969178 ! peptide hormone binding GO:0017046 16 15 0,000 0,01670163 0,02967732 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,01670163 0,02966287 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,01670163 0,02964843 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,01670163 0,02963401 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,01670163 0,02961961 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,01670163 0,02960521 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,01670163 0,02959084 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,01670163 0,02957647 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,01670163 0,02956212 ! developmental induction GO:0031128 17 15 0,000 0,01670163 0,02954778 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,01670163 0,02953346 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,01670163 0,02951915 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,01670163 0,02950486 ! lactation GO:0007595 17 15 0,000 0,01670163 0,02949058 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,01670163 0,02947631 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01670163 0,02946206 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01670163 0,02944782 ! double-strand break repair via homologous recombination GO:0000724 36 15 0,000 0,01670163 0,02943359 GO:0000725|recombinational repair, ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,01670163 0,02941938 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,01670163 0,02940518 ! sulfate transport GO:0008272 16 15 0,000 0,01670163 0,02939099 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,01670163 0,02937682 ! bile acid metabolic process GO:0008206 17 15 0,000 0,01670163 0,02936267 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,01670163 0,02934852 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,01670163 0,02933439 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,01670163 0,02932028 ! heart looping GO:0001947 18 15 0,000 0,01670163 0,02930617 ! protein kinase C activity GO:0004697 17 15 0,000 0,01670163 0,02929208 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,01670163 0,02927801 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,01670163 0,02926394 ! pigmentation during development GO:0048066 17 15 0,000 0,01670163 0,0292499 ! cytokine metabolic process GO:0042107 15 15 0,000 0,01670163 0,02923586 ! vesicle coating GO:0006901 17 15 0,000 0,01670163 0,02922184 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,01670163 0,02920783 ! neutral amino acid transport GO:0015804 18 15 0,000 0,01670163 0,02919383 ! L-amino acid transport GO:0015807 16 15 0,000 0,01670163 0,02917985 ! microfilament motor activity GO:0000146 15 15 0,000 0,01670163 0,02916588 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,01670163 0,02915193 ! regulation of vasodilation GO:0042312 25 15 0,000 0,01670163 0,02913799 ! DNA replication initiation GO:0006270 15 15 0,000 0,01670163 0,02912406 ! taste receptor activity GO:0008527 15 15 0,000 0,01670163 0,02911014 ! cellular pigmentation GO:0033059 16 15 0,000 0,01670163 0,02909624 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,01670163 0,02908235 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,01670163 0,02906848 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,01670163 0,02905462 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,01670163 0,02904077 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,01670163 0,02902693 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,01670163 0,02901311 ! ion gated channel activity GO:0022839 17 15 0,000 0,01670163 0,0289993 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,01670163 0,0289855 ! receptor activator activity GO:0030546 17 15 0,000 0,01670163 0,02897172 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,01670163 0,02895795 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,01670163 0,0289442 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,01670163 0,02893045 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,01670163 0,02891672 ! peptide hormone processing GO:0016486 19 15 0,000 0,01670163 0,028903 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01670163 0,0288893 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,01780557 0,03078423 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01780557 0,03076964 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,01780557 0,03075507 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,01780557 0,03074052 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,01780557 0,03072598 ! kinesin complex GO:0005871 16 16 0,000 0,01780557 0,03071145 ! photoreceptor cell development GO:0042461 22 16 0,000 0,01780557 0,03069694 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,01780557 0,03068244 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,01780557 0,03066795 ! centrosome cycle GO:0007098 26 16 0,000 0,01780557 0,03065348 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,01780557 0,03063902 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,01780557 0,03062457 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,01780557 0,03061014 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,01780557 0,03059572 ! lysosomal transport GO:0007041 16 16 0,000 0,01780557 0,03058132 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,01780557 0,03056693 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,01780557 0,03055255 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,01780557 0,03053818 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,01780557 0,03052383 ! myofibril assembly GO:0030239 17 16 0,000 0,01780557 0,0305095 GO:0055002|striated muscle cell development, ! G1 phase GO:0051318 17 16 0,000 0,01780557 0,03049517 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,01780557 0,03048086 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,01780557 0,03046657 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,01780557 0,03045228 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,01780557 0,03043801 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,01780557 0,03042376 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,01780557 0,03040951 ! steroid catabolic process GO:0006706 18 16 0,000 0,01780557 0,03039528 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,01780557 0,03038107 ! cell-cell recognition GO:0009988 19 16 0,000 0,01780557 0,03036686 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,01780557 0,03035267 ! spleen development GO:0048536 19 16 0,000 0,01780557 0,0303385 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,01780557 0,03032433 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,01780557 0,03031018 ! neural tube closure GO:0001843 19 16 0,000 0,01780557 0,03029604 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,01780557 0,03028192 ! regulation of protein ubiquitination GO:0031396 27 16 0,000 0,01780557 0,03026781 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,01780557 0,03025371 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,01780557 0,03023963 ! viral genome replication GO:0019079 16 16 0,000 0,01780557 0,03022556 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,01780557 0,0302115 ! memory GO:0007613 18 16 0,000 0,01780557 0,03019745 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,01780557 0,03018342 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01780557 0,0301694 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,01780557 0,03015539 ! glycoprotein binding GO:0001948 19 16 0,000 0,01780557 0,0301414 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,01780557 0,03012742 ! syntaxin binding GO:0019905 18 16 0,000 0,01780557 0,03011345 ! myosin binding GO:0017022 17 16 0,000 0,01780557 0,0300995 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,01780557 0,03008556 ! fucose metabolic process GO:0006004 18 16 0,000 0,01780557 0,03007163 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,01780557 0,03005771 ! membrane budding GO:0006900 18 16 0,000 0,01780557 0,03004381 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,01780557 0,03002992 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,01780557 0,03001604 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,01780557 0,03000218 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,01780557 0,02998833 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,01780557 0,02997449 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,01780557 0,02996066 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,01780557 0,02994685 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,01780557 0,02993305 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,01780557 0,02991926 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,01780557 0,02990549 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01780557 0,02989172 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,01780557 0,02987798 ! axoneme GO:0005930 16 16 0,000 0,01780557 0,02986424 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,01780557 0,02985051 ! anion exchanger activity GO:0015380 17 17 0,000 0,01890833 0,0316847 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,01890833 0,03167016 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,01890833 0,03165562 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,01890833 0,0316411 ! glial cell development GO:0021782 17 17 0,000 0,01890833 0,03162659 ! limbic system development GO:0021761 18 17 0,000 0,01890833 0,0316121 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,01890833 0,03159762 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,01890833 0,03158315 ! ephrin receptor activity GO:0005003 21 17 0,000 0,01890833 0,03156869 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,01890833 0,03155425 ! glutamine metabolic process GO:0006541 26 17 0,000 0,01890833 0,03153983 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,01890833 0,03152541 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,01890833 0,03151101 ! signal sequence binding GO:0005048 18 17 0,000 0,01890833 0,03149662 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,01890833 0,03148224 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01890833 0,03146788 ! organelle subcompartment GO:0031984 19 17 0,000 0,01890833 0,03145353 ! regulation of dephosphorylation GO:0035303 20 17 0,000 0,01890833 0,0314392 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,01890833 0,03142487 ! membrane depolarization GO:0051899 19 17 0,000 0,01890833 0,03141056 ! oogenesis GO:0048477 20 17 0,000 0,01890833 0,03139627 ! nuclear outer membrane GO:0005640 21 17 0,000 0,01890833 0,03138198 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,01890833 0,03136771 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,01890833 0,03135345 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,01890833 0,03133921 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,01890833 0,03132498 ! organic cation transport GO:0015695 17 17 0,000 0,01890833 0,03131076 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,01890833 0,03129655 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,01890833 0,03128236 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,01890833 0,03126818 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,01890833 0,03125401 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,01890833 0,03123985 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,01890833 0,03122571 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,01890833 0,03121158 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,01890833 0,03119747 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01890833 0,03118336 ! lipid localization GO:0010876 19 17 0,000 0,01890833 0,03116927 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,01890833 0,03115519 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,01890833 0,03114113 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,01890833 0,03112707 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,01890833 0,03111303 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,01890833 0,03109901 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,01890833 0,03108499 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,01890833 0,03107099 ! response to hexose stimulus GO:0009746 20 17 0,000 0,01890833 0,031057 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,01890833 0,03104302 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,01890833 0,03102906 ! AMP binding GO:0016208 19 17 0,000 0,01890833 0,03101511 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,01890833 0,03100117 ! receptor metabolic process GO:0043112 20 17 0,000 0,01890833 0,03098724 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,01890833 0,03097333 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,01890833 0,03095942 ! alcohol binding GO:0043178 20 17 0,000 0,01890833 0,03094554 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,01890833 0,03093166 ! visual learning GO:0008542 31 17 0,000 0,01890833 0,03091779 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,01890833 0,03090394 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,01890833 0,0308901 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,01890833 0,03087627 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,01890833 0,03086246 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,01890833 0,03084866 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,01890833 0,03083487 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,01890833 0,03082109 ! translation elongation factor activity GO:0003746 19 17 0,000 0,01890833 0,03080732 ! histone binding GO:0042393 26 17 0,000 0,01890833 0,03079357 ! cilium assembly GO:0042384 18 17 0,000 0,01890833 0,03077983 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,01890833 0,0307661 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,01890833 0,03075238 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,01890833 0,03073868 ! protein secretion GO:0009306 19 18 0,000 0,02000992 0,032515 ! positive regulation of ossification GO:0045778 19 18 0,000 0,02000992 0,03250052 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,02000992 0,03248606 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,02000992 0,03247161 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,02000992 0,03245717 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,02000992 0,03244275 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,02000992 0,03242833 ! cAMP metabolic process GO:0046058 18 18 0,000 0,02000992 0,03241393 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,02000992 0,03239955 ! cornified envelope GO:0001533 22 18 0,000 0,02000992 0,03238517 ! retinoid metabolic process GO:0001523 19 18 0,000 0,02000992 0,03237081 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,02000992 0,03235646 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,02000992 0,03234213 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,02000992 0,0323278 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,02000992 0,03231349 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,02000992 0,03229919 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,02000992 0,03228491 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,02000992 0,03227064 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,02000992 0,03225637 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,02000992 0,03224213 ! primary neural tube formation GO:0014020 21 18 0,000 0,02000992 0,03222789 ! recycling endosome GO:0055037 22 18 0,000 0,02000992 0,03221367 ! muscle cell development GO:0055001 20 18 0,000 0,02000992 0,03219946 ! kinase activator activity GO:0019209 22 18 0,000 0,02000992 0,03218526 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,02000992 0,03217108 ! cerebellum development GO:0021549 20 18 0,000 0,02000992 0,03215691 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,02000992 0,03214275 ! somitogenesis GO:0001756 20 18 0,000 0,02000992 0,0321286 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,02000992 0,03211446 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,02000992 0,03210034 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,02000992 0,03208623 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,02000992 0,03207213 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,02000992 0,03205805 ! basal plasma membrane GO:0009925 21 18 0,000 0,02000992 0,03204398 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,02000992 0,03202992 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,02000992 0,03201587 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,02000992 0,03200183 ! negative regulation of translation GO:0017148 31 18 0,000 0,02000992 0,03198781 ! regulation of cell killing GO:0031341 24 18 0,000 0,02000992 0,0319738 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,02000992 0,0319598 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,02000992 0,03194581 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,02000992 0,03193184 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,02000992 0,03191787 ! protein complex scaffold GO:0032947 22 18 0,000 0,02000992 0,03190392 ! SNAP receptor activity GO:0005484 21 18 0,000 0,02000992 0,03188999 ! dendrite development GO:0016358 22 18 0,000 0,02000992 0,03187606 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,02000992 0,03186215 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,02000992 0,03184824 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,02000992 0,03183436 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,02000992 0,03182048 ! nuclear ubiquitin ligase complex GO:0000152 31 18 0,000 0,02000992 0,03180661 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,02000992 0,03179276 ! coreceptor activity GO:0015026 28 18 0,000 0,02000992 0,03177892 ! response to fungus GO:0009620 18 18 0,000 0,02000992 0,03176509 ! stem cell differentiation GO:0048863 18 18 0,000 0,02000992 0,03175127 ! intermediate filament-based process GO:0045103 18 18 0,000 0,02000992 0,03173747 ! heart process GO:0003015 19 18 0,000 0,02000992 0,03172368 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,02000992 0,03170989 ! vasodilation GO:0042311 20 18 0,000 0,02000992 0,03169613 ! transport vesicle membrane GO:0030658 23 18 0,000 0,02000992 0,03168237 ! MHC protein binding GO:0042287 30 18 0,000 0,02000992 0,03166862 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,02000992 0,03165489 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,02000992 0,03164117 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,02000992 0,03162746 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,02000992 0,03161376 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,02000992 0,03160008 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,02000992 0,0315864 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,02000992 0,03157274 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,02000992 0,03155909 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,02111032 0,03328023 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,02111032 0,03326586 ! proteasome core complex GO:0005839 20 19 0,000 0,02111032 0,03325149 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,02111032 0,03323714 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,02111032 0,0332228 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,02111032 0,03320848 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,02111032 0,03319416 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,02111032 0,03317986 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,02111032 0,03316557 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,02111032 0,03315129 ! lysosome organization GO:0007040 20 19 0,000 0,02111032 0,03313703 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,02111032 0,03312278 ! central nervous system neuron development GO:0021954 21 19 0,000 0,02111032 0,03310854 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,02111032 0,03309431 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,02111032 0,03308009 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,02111032 0,03306589 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,02111032 0,0330517 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,02111032 0,03303752 ! peptide cross-linking GO:0018149 23 19 0,000 0,02111032 0,03302335 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,02111032 0,0330092 ! beta-catenin binding GO:0008013 23 19 0,000 0,02111032 0,03299505 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,02111032 0,03298092 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,02111032 0,03296681 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02111032 0,0329527 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,02111032 0,0329386 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,02111032 0,03292452 ! vitamin transport GO:0051180 21 19 0,000 0,02111032 0,03291045 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,02111032 0,03289639 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,02111032 0,03288235 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,02111032 0,03286831 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,02111032 0,03285429 ! retinoid binding GO:0005501 19 19 0,000 0,02111032 0,03284028 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,02111032 0,03282628 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,02111032 0,0328123 ! histone deacetylase activity GO:0004407 20 19 0,000 0,02111032 0,03279832 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,02111032 0,03278436 ! gluconeogenesis GO:0006094 23 19 0,000 0,02111032 0,03277041 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,02111032 0,03275647 ! microtubule-based transport GO:0010970 20 19 0,000 0,02111032 0,03274254 ! superoxide metabolic process GO:0006801 21 19 0,000 0,02111032 0,03272863 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,02111032 0,03271472 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02111032 0,03270083 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,02111032 0,03268695 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,02111032 0,03267308 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,02111032 0,03265923 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,02111032 0,03264538 ! acetylcholine binding GO:0042166 20 19 0,000 0,02111032 0,03263155 ! heme metabolic process GO:0042168 20 19 0,000 0,02111032 0,03261773 ! SH2 domain binding GO:0042169 25 19 0,000 0,02111032 0,03260392 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,02111032 0,03259012 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,02111032 0,03257634 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,02111032 0,03256256 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,02111032 0,0325488 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,02111032 0,03253505 ! body fluid secretion GO:0007589 21 19 0,000 0,02111032 0,03252131 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,02111032 0,03250758 ! secretory granule membrane GO:0030667 21 19 0,000 0,02111032 0,03249386 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,02111032 0,03248016 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,02111032 0,03246647 ! peptidase activator activity GO:0016504 21 19 0,000 0,02111032 0,03245278 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02111032 0,03243911 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,02111032 0,03242546 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,02111032 0,03241181 ! sialyltransferase activity GO:0008373 31 19 0,000 0,02111032 0,03239817 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,02111032 0,03238455 ! chaperone binding GO:0051087 21 20 0,000 0,02220955 0,03405651 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,02220955 0,0340422 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,02220955 0,03402791 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,02220955 0,03401362 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,02220955 0,03399935 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,02220955 0,03398509 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,02220955 0,03397084 ! negative regulation of lipid metabolic process GO:0045833 34 20 0,000 0,02220955 0,0339566 ! ovarian follicle development GO:0001541 21 20 0,000 0,02220955 0,03394237 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 0,000 0,02220955 0,03392816 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,02220955 0,03391396 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,02220955 0,03389977 ! diencephalon development GO:0021536 22 20 0,000 0,02220955 0,03388559 ! nuclear inner membrane GO:0005637 21 20 0,000 0,02220955 0,03387142 ! regulation of lipid transport GO:0032368 22 20 0,000 0,02220955 0,03385727 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,02220955 0,03384313 ! glutathione metabolic process GO:0006749 21 20 0,000 0,02220955 0,033829 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,02220955 0,03381488 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,02220955 0,03380077 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,02220955 0,03378667 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,02220955 0,03377259 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,02220955 0,03375852 ! peptide hormone secretion GO:0030072 25 20 0,000 0,02220955 0,03374446 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,02220955 0,03373041 ! Rab GTPase binding GO:0017137 22 20 0,000 0,02220955 0,03371637 ! initiation of viral infection GO:0019059 22 20 0,000 0,02220955 0,03370235 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,02220955 0,03368833 ! heterochromatin GO:0000792 20 20 0,000 0,02220955 0,03367433 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,02220955 0,03366034 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,02220955 0,03364636 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,02220955 0,0336324 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,02220955 0,03361844 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,02220955 0,0336045 ! visual behavior GO:0007632 34 20 0,000 0,02220955 0,03359057 ! regulation of cell-matrix adhesion GO:0001952 26 20 0,000 0,02220955 0,03357665 GO:0010810|regulation of cell-substrate adhesion, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,02220955 0,03356274 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,02220955 0,03354884 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,02220955 0,03353495 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,02220955 0,03352108 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,02220955 0,03350721 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,02220955 0,03349336 ! rRNA binding GO:0019843 22 20 0,000 0,02220955 0,03347952 ! cytolysis GO:0019835 22 20 0,000 0,02220955 0,03346569 ! renal system process GO:0003014 22 20 0,000 0,02220955 0,03345188 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,02220955 0,03343807 ! fatty acid transport GO:0015908 23 20 0,000 0,02220955 0,03342428 ! transaminase activity GO:0008483 22 20 0,000 0,02220955 0,03341049 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,02220955 0,03339672 ! collagen catabolic process GO:0030574 21 20 0,000 0,02220955 0,03338296 ! microvillus GO:0005902 25 20 0,000 0,02220955 0,03336921 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,02220955 0,03335547 ! connexon complex GO:0005922 23 20 0,000 0,02220955 0,03334175 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,02330761 0,03497579 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,02330761 0,03496141 ! translational initiation GO:0006413 21 21 0,000 0,02330761 0,03494704 ! NF-kappaB binding GO:0051059 31 21 0,000 0,02330761 0,03493268 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,02330761 0,03491833 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,02330761 0,034904 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,02330761 0,03488968 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,02330761 0,03487537 ! glutathione transferase activity GO:0004364 21 21 0,000 0,02330761 0,03486107 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,02330761 0,03484678 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,02330761 0,0348325 ! regeneration GO:0031099 24 21 0,000 0,02330761 0,03481824 ! MHC class I protein complex GO:0042612 31 21 0,000 0,02330761 0,03480399 ! cellular response to starvation GO:0009267 22 21 0,000 0,02330761 0,03478975 ! peroxisome organization GO:0007031 22 21 0,000 0,02330761 0,03477552 ! vacuole organization GO:0007033 23 21 0,000 0,02330761 0,0347613 ! apoptotic nuclear changes GO:0030262 24 21 0,000 0,02330761 0,0347471 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,02330761 0,0347329 ! neural crest cell development GO:0014032 24 21 0,000 0,02330761 0,03471872 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,02330761 0,03470455 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,02330761 0,03469039 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,02330761 0,03467624 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02330761 0,03466211 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,02330761 0,03464798 ! pallium development GO:0021543 22 21 0,000 0,02330761 0,03463387 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,02330761 0,03461977 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,02330761 0,03460568 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,02330761 0,0345916 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,02330761 0,03457753 ! cyclase activity GO:0009975 22 21 0,000 0,02330761 0,03456347 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,02330761 0,03454943 ! gut development GO:0048565 23 21 0,000 0,02330761 0,0345354 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,02330761 0,03452137 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,02330761 0,03450736 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02330761 0,03449336 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,02330761 0,03447938 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02330761 0,0344654 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,02330761 0,03445144 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,02330761 0,03443748 ! axis specification GO:0009798 25 21 0,000 0,02330761 0,03442354 ! response to alkaloid GO:0043279 27 21 0,000 0,02330761 0,03440961 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,02330761 0,03439569 ! response to ethanol GO:0045471 28 21 0,000 0,02330761 0,03438178 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,02330761 0,03436788 ! smooth muscle contraction GO:0006939 25 21 0,000 0,02330761 0,034354 ! ubiquitin binding GO:0043130 25 21 0,000 0,02330761 0,03434012 ! vesicle targeting GO:0006903 22 21 0,000 0,02330761 0,03432626 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,02330761 0,03431241 ! SNARE binding GO:0000149 24 21 0,000 0,02330761 0,03429857 ! interaction with host GO:0051701 26 21 0,000 0,02330761 0,03428474 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,02330761 0,03427092 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,02330761 0,03425711 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,02330761 0,03424331 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,02330761 0,03422953 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,02330761 0,03421575 ! cell-cell junction organization GO:0045216 24 21 0,000 0,02330761 0,03420199 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,02330761 0,03418824 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,02330761 0,0341745 ! caveola GO:0005901 25 21 0,000 0,02330761 0,03416076 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,02330761 0,03414705 ! insulin receptor binding GO:0005158 25 21 0,000 0,02330761 0,03413334 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02330761 0,03411964 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02330761 0,03410595 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,02440448 0,0356967 ! metencephalon development GO:0022037 25 22 0,000 0,02440448 0,03568239 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,02440448 0,03566809 ! hormone secretion GO:0046879 28 22 0,000 0,02440448 0,03565381 ! vesicle docking GO:0048278 24 22 0,000 0,02440448 0,03563954 ! muscle myosin complex GO:0005859 23 22 0,000 0,02440448 0,03562527 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,02440448 0,03561102 ! actomyosin structure organization GO:0031032 24 22 0,000 0,02440448 0,03559678 ! microtubule organizing center organization GO:0031023 33 22 0,000 0,02440448 0,03558256 GO:0051297|centrosome organization, ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,02440448 0,03556834 ! sperm motility GO:0030317 23 22 0,000 0,02440448 0,03555414 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,02440448 0,03553994 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,02440448 0,03552576 ! vacuolar transport GO:0007034 22 22 0,000 0,02440448 0,03551159 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,02440448 0,03549743 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,02440448 0,03548328 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,02440448 0,03546915 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,02440448 0,03545502 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,02440448 0,03544091 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,02440448 0,0354268 ! PML body GO:0016605 25 22 0,000 0,02440448 0,03541271 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,02440448 0,03539863 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,02440448 0,03538456 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,02440448 0,0353705 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,02440448 0,03535646 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,02440448 0,03534242 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,02440448 0,0353284 ! deacetylase activity GO:0019213 23 22 0,000 0,02440448 0,03531438 ! pentose metabolic process GO:0019321 23 22 0,000 0,02440448 0,03530038 ! collagen fibril organization GO:0030199 32 22 0,000 0,02440448 0,03528639 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,02440448 0,03527241 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,02440448 0,03525844 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,02440448 0,03524448 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,02440448 0,03523053 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,02440448 0,0352166 ! positive regulation of behavior GO:0048520 24 22 0,000 0,02440448 0,03520267 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,02440448 0,03518876 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,02440448 0,03517486 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,02440448 0,03516096 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,02440448 0,03514708 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,02440448 0,03513321 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,02440448 0,03511935 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,02440448 0,0351055 ! glycerol metabolic process GO:0006071 24 22 0,000 0,02440448 0,03509167 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,02440448 0,03507784 ! nuclear chromatin GO:0000790 23 22 0,000 0,02440448 0,03506402 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,02440448 0,03505022 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,02440448 0,03503643 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,02440448 0,03502264 ! sterol binding GO:0032934 24 22 0,000 0,02440448 0,03500887 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,02440448 0,03499511 ! digestive system process GO:0022600 25 22 0,000 0,02440448 0,03498136 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,02440448 0,03496762 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,02440448 0,03495389 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,02440448 0,03494017 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,02440448 0,03492646 ! base-excision repair GO:0006284 33 22 0,000 0,02440448 0,03491277 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,02440448 0,03489908 ! DNA modification GO:0006304 25 22 0,000 0,02440448 0,03488541 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,02440448 0,03487174 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,02440448 0,03485809 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,02440448 0,03484445 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,02440448 0,03483081 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,02440448 0,03481719 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,02440448 0,03480358 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,02440448 0,03478998 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,02440448 0,03477639 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,02550019 0,03632358 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,02550019 0,0363094 ! leukocyte adhesion GO:0007159 26 23 0,000 0,02550019 0,03629524 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,02550019 0,03628108 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,02550019 0,03626694 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,02550019 0,0362528 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,02550019 0,03623868 ! ureteric bud development GO:0001657 24 23 0,000 0,02550019 0,03622457 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,02550019 0,03621047 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,02550019 0,03619638 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,02550019 0,0361823 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,02550019 0,03616823 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,02550019 0,03615418 ! deaminase activity GO:0019239 24 23 0,000 0,02550019 0,03614013 ! sensory perception of pain GO:0019233 26 23 0,000 0,02550019 0,03612609 ! lipid kinase activity GO:0001727 26 23 0,000 0,02550019 0,03611207 ! platelet activation GO:0030168 27 23 0,000 0,02550019 0,03609806 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,02550019 0,03608405 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,02550019 0,03607006 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,02550019 0,03605608 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,02550019 0,03604211 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,02550019 0,03602815 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,02550019 0,03601421 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,02550019 0,03600027 ! cell surface binding GO:0043498 28 23 0,000 0,02550019 0,03598634 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,02550019 0,03597243 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,02550019 0,03595852 ! regulation of glucose import GO:0046324 28 23 0,000 0,02550019 0,03594463 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,02550019 0,03593074 ! alditol metabolic process GO:0019400 25 23 0,000 0,02550019 0,03591687 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,02550019 0,03590301 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,02550019 0,03588916 ! zinc ion transport GO:0006829 26 23 0,000 0,02550019 0,03587532 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,02550019 0,03586149 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,02550019 0,03584767 ! sex determination GO:0007530 25 23 0,000 0,02550019 0,03583386 ! phosphate binding GO:0042301 25 23 0,000 0,02550019 0,03582006 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,02550019 0,03580627 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,02550019 0,03579249 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,02550019 0,03577873 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,02550019 0,03576497 ! synaptogenesis GO:0007416 25 23 0,000 0,02550019 0,03575123 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,02550019 0,03573749 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,02550019 0,03572377 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,02550019 0,03571005 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,02550019 0,03569635 ! leukocyte proliferation GO:0070661 26 23 0,000 0,02550019 0,03568266 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,02550019 0,03566898 ! growth cone GO:0030426 27 24 0,000 0,02659472 0,03718572 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,02659472 0,03717148 ! actin filament GO:0005884 26 24 0,000 0,02659472 0,03715724 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02659472 0,03714301 ! pancreas development GO:0031016 27 24 0,000 0,02659472 0,0371288 ! androgen receptor binding GO:0050681 34 24 0,000 0,02659472 0,0371146 ! calcium channel complex GO:0034704 31 24 0,000 0,02659472 0,0371004 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,02659472 0,03708622 ! negative regulation of cell development GO:0010721 30 24 0,000 0,02659472 0,03707205 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,02659472 0,03705789 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,02659472 0,03704374 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,02659472 0,0370296 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,02659472 0,03701547 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,02659472 0,03700135 ! Rho GTPase binding GO:0017048 36 24 0,000 0,02659472 0,03698725 ! regulation of glucose transport GO:0010827 29 24 0,000 0,02659472 0,03697315 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,02659472 0,03695907 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,02659472 0,03694499 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,02659472 0,03693093 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,02659472 0,03691688 ! protein stabilization GO:0050821 24 24 0,000 0,02659472 0,03690283 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,02659472 0,0368888 ! embryonic pattern specification GO:0009880 29 24 0,000 0,02659472 0,03687478 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,02659472 0,03686077 ! RNA polymerase complex GO:0030880 25 24 0,000 0,02659472 0,03684677 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,02659472 0,03683278 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,02659472 0,03681881 ! small conjugating protein binding GO:0032182 29 24 0,000 0,02659472 0,03680484 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,02659472 0,03679088 ! chemokine binding GO:0019956 26 24 0,000 0,02659472 0,03677693 ! catechol metabolic process GO:0009712 29 24 0,000 0,02659472 0,036763 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,02659472 0,03674907 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,02659472 0,03673516 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,02659472 0,03672125 ! cell aging GO:0007569 47 24 0,000 0,02659472 0,03670736 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,02659472 0,03669348 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,02659472 0,0366796 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,02659472 0,03666574 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,02659472 0,03665189 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,02659472 0,03663805 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,02659472 0,03662422 ! caspase regulator activity GO:0043028 26 24 0,000 0,02659472 0,0366104 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 0,000 0,02659472 0,03659659 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,02659472 0,03658279 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,02659472 0,036569 ! selenium binding GO:0008430 24 24 0,000 0,02659472 0,03655522 ! spindle pole GO:0000922 35 24 0,000 0,02659472 0,03654145 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,02659472 0,03652769 ! site of polarized growth GO:0030427 28 25 0,000 0,02768809 0,03801511 ! phenol metabolic process GO:0018958 31 25 0,000 0,02768809 0,0380008 ! regulation of lipid biosynthetic process GO:0046890 35 25 0,000 0,02768809 0,03798651 ! protein amino acid acylation GO:0043543 28 25 0,000 0,02768809 0,03797223 ! aromatase activity GO:0070330 28 25 0,000 0,02768809 0,03795796 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,02768809 0,0379437 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,02768809 0,03792946 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,02768809 0,03791522 ! response to starvation GO:0042594 26 25 0,000 0,02768809 0,03790099 ! dynein complex GO:0030286 28 25 0,000 0,02768809 0,03788677 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,02768809 0,03787257 ! regulation of behavior GO:0050795 27 25 0,000 0,02768809 0,03785837 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,02768809 0,03784419 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,02768809 0,03783001 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,02768809 0,03781585 ! hormone transport GO:0009914 31 25 0,000 0,02768809 0,0378017 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,02768809 0,03778756 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,02768809 0,03777343 ! regulation of coagulation GO:0050818 28 25 0,000 0,02768809 0,0377593 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,02768809 0,03774519 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,02768809 0,03773109 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,02768809 0,037717 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,02768809 0,03770293 ! molting cycle process GO:0022404 28 25 0,000 0,02768809 0,03768886 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,02768809 0,0376748 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,02768809 0,03766075 ! phototransduction GO:0007602 27 25 0,000 0,02768809 0,03764672 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,02768809 0,03763269 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,02768809 0,03761867 ! protein phosphatase binding GO:0019903 27 25 0,000 0,02768809 0,03760467 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,02768809 0,03759067 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,02768809 0,03757669 ! autophagy GO:0006914 28 25 0,000 0,02768809 0,03756271 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,02768809 0,03754875 ! response to ionizing radiation GO:0010212 37 25 0,000 0,02768809 0,0375348 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,02768809 0,03752085 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,02878028 0,03898643 ! positive regulation of cell adhesion GO:0045785 34 26 0,000 0,02878028 0,03897196 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,02878028 0,0389575 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,02878028 0,03894305 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,02878028 0,03892861 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,02878028 0,03891418 ! hair cycle GO:0042633 29 26 0,000 0,02878028 0,03889976 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,02878028 0,03888536 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,02878028 0,03887096 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,02878028 0,03885657 ! early endosome membrane GO:0031901 31 26 0,000 0,02878028 0,0388422 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,02878028 0,03882783 ! iron ion homeostasis GO:0055072 29 26 0,000 0,02878028 0,03881348 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,02878028 0,03879914 ! GABA receptor activity GO:0016917 31 26 0,000 0,02878028 0,0387848 ! PDZ domain binding GO:0030165 28 26 0,000 0,02878028 0,03877048 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,02878028 0,03875617 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,02878028 0,03874187 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,02878028 0,03872758 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,02878028 0,0387133 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,02878028 0,03869903 ! fatty acid binding GO:0005504 28 26 0,000 0,02878028 0,03868477 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,02878028 0,03867052 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,02878028 0,03865628 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,02878028 0,03864205 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,02878028 0,03862784 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,02878028 0,03861363 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02878028 0,03859943 ! iron ion transport GO:0006826 33 26 0,000 0,02878028 0,03858525 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,02878028 0,03857107 ! glucose transport GO:0015758 27 26 0,000 0,02878028 0,03855691 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,02878028 0,03854275 ! spinal cord development GO:0021510 30 26 0,000 0,02878028 0,03852861 ! histone deacetylase complex GO:0000118 29 26 0,000 0,02878028 0,03851448 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,02878028 0,03850035 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,02878028 0,03848624 ! RNA helicase activity GO:0003724 46 26 0,000 0,02878028 0,03847214 ! brush border GO:0005903 30 26 0,000 0,02878028 0,03845804 ! gap junction GO:0005921 29 26 0,000 0,02878028 0,03844396 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,02878028 0,03842989 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,0298713 0,03987212 ! RNA export from nucleus GO:0006405 31 27 0,000 0,0298713 0,03985754 ! mRNA catabolic process GO:0006402 31 27 0,000 0,0298713 0,03984297 ! myelination GO:0042552 31 27 0,000 0,0298713 0,03982841 ! trans-Golgi network GO:0005802 31 27 0,000 0,0298713 0,03981385 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,0298713 0,03979931 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,0298713 0,03978478 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,0298713 0,03977026 ! vasculogenesis GO:0001570 32 27 0,000 0,0298713 0,03975575 ! hexose transport GO:0008645 28 27 0,000 0,0298713 0,03974125 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,0298713 0,03972677 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,0298713 0,03971229 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,0298713 0,03969782 ! cell fate determination GO:0001709 29 27 0,000 0,0298713 0,03968336 ! lipid oxidation GO:0034440 29 27 0,000 0,0298713 0,03966892 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,0298713 0,03965448 ! collagen binding GO:0005518 29 27 0,000 0,0298713 0,03964006 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,0298713 0,03962564 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,0298713 0,03961124 ! liver development GO:0001889 33 27 0,000 0,0298713 0,03959685 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,0298713 0,03958246 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,0298713 0,03956809 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,0298713 0,03955373 ! membrane docking GO:0022406 29 27 0,000 0,0298713 0,03953938 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,0298713 0,03952503 GO:0050908|detection of light stimulus involved in visual perception, ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,0298713 0,0395107 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,0298713 0,03949638 ! phospholipid transport GO:0015914 29 27 0,000 0,0298713 0,03948207 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,0298713 0,03946777 ! aminopeptidase activity GO:0004177 33 27 0,000 0,0298713 0,03945348 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,0298713 0,0394392 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,0298713 0,03942493 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,0298713 0,03941068 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,0298713 0,03939643 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,0298713 0,03938219 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,03096116 0,04080431 ! Golgi stack GO:0005795 30 28 0,000 0,03096116 0,04078957 ! male gonad development GO:0008584 32 28 0,000 0,03096116 0,04077484 ! regulation of fatty acid metabolic process GO:0019217 41 28 0,000 0,03096116 0,04076013 ! lipoprotein binding GO:0008034 31 28 0,000 0,03096116 0,04074542 ! mesoderm formation GO:0001707 34 28 0,000 0,03096116 0,04073073 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,03096116 0,04071605 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,03096116 0,04070138 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,03096116 0,04068671 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,03096116 0,04067206 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,03096116 0,04065742 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,03096116 0,04064279 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,03096116 0,04062817 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,03096116 0,04061356 ! tissue homeostasis GO:0001894 31 28 0,000 0,03096116 0,04059896 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,03096116 0,04058438 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,03096116 0,0405698 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,03096116 0,04055523 ! sister chromatid segregation GO:0000819 49 28 0,000 0,03096116 0,04054067 ! post-embryonic development GO:0009791 32 28 0,000 0,03096116 0,04052613 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,03096116 0,04051159 ! detection of visible light GO:0009584 30 28 0,000 0,03096116 0,04049707 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,03096116 0,04048255 ! receptor regulator activity GO:0030545 31 28 0,000 0,03096116 0,04046805 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,03096116 0,04045355 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,03096116 0,04043907 ! response to heat GO:0009408 33 28 0,000 0,03096116 0,04042459 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,03096116 0,04041013 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,03204985 0,04181612 ! hormone binding GO:0042562 31 29 0,000 0,03204985 0,04180117 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,03204985 0,04178623 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,03204985 0,0417713 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,03204985 0,04175638 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,03204985 0,04174147 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,03204985 0,04172657 ! erythrocyte differentiation GO:0030218 35 29 0,000 0,03204985 0,04171169 ! ceramide metabolic process GO:0006672 29 29 0,000 0,03204985 0,04169681 ! replication fork GO:0005657 42 29 0,000 0,03204985 0,04168195 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,03204985 0,04166709 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,03204985 0,04165225 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,03204985 0,04163742 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,03204985 0,04162259 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,03204985 0,04160778 ! regulation of pH GO:0006885 30 29 0,000 0,03204985 0,04159298 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,03204985 0,04157819 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,03204985 0,04156341 ! phospholipase C activity GO:0004629 43 29 0,000 0,03204985 0,04154864 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,03204985 0,04153388 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,03204985 0,04151913 ! sodium channel activity GO:0005272 33 29 0,000 0,03204985 0,04150439 ! sarcoplasm GO:0016528 31 29 0,000 0,03204985 0,04148966 ! detection of light stimulus GO:0009583 31 29 0,000 0,03204985 0,04147494 ! spermatid development GO:0007286 30 29 0,000 0,03204985 0,04146023 ! DNA polymerase activity GO:0034061 34 29 0,000 0,03204985 0,04144554 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,03204985 0,04143085 ! sarcolemma GO:0042383 30 29 0,000 0,03204985 0,04141618 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,03204985 0,04140151 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,03204985 0,04138685 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,03204985 0,04137221 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,03313738 0,04276093 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,03313738 0,04274581 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,03313738 0,0427307 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,03313738 0,0427156 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,03313738 0,04270052 ! scavenger receptor activity GO:0005044 39 30 0,000 0,03313738 0,04268544 ! spliceosome assembly GO:0000245 34 30 0,000 0,03313738 0,04267037 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,03313738 0,04265531 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,03313738 0,04264027 ! metanephros development GO:0001656 31 30 0,000 0,03313738 0,04262523 ! glutamate receptor activity GO:0008066 35 30 0,000 0,03313738 0,04261021 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,03313738 0,04259519 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,03313738 0,04258019 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,03313738 0,0425652 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,03313738 0,04255021 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,03313738 0,04253524 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,03313738 0,04252028 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,03313738 0,04250533 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,03313738 0,04249039 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,03313738 0,04247546 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,03313738 0,04246054 ! protein-lipid complex GO:0032994 41 30 0,000 0,03313738 0,04244563 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,03313738 0,04243073 ! negative regulation of protein modification process GO:0031400 34 30 0,000 0,03313738 0,04241584 ! phosphatase binding GO:0019902 34 30 0,000 0,03313738 0,04240097 ! acute-phase response GO:0006953 44 30 0,000 0,03313738 0,0423861 ! segmentation GO:0035282 37 30 0,000 0,03313738 0,04237124 ! response to toxin GO:0009636 33 30 0,000 0,03313738 0,0423564 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,03313738 0,04234156 ! antigen binding GO:0003823 33 30 0,000 0,03313738 0,04232674 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,03313738 0,04231192 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,03313738 0,04229712 ! ensheathment of neurons GO:0007272 35 30 0,000 0,03313738 0,04228232 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,03313738 0,04226754 ! regulation of microtubule-based process GO:0032886 41 30 0,000 0,03313738 0,04225276 ! vesicle localization GO:0051648 31 30 0,000 0,03313738 0,042238 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,03422374 0,04360748 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03422374 0,04359225 ! acrosomal vesicle GO:0001669 34 31 0,000 0,03422374 0,04357704 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03422374 0,04356183 ! protein targeting to membrane GO:0006612 35 31 0,000 0,03422374 0,04354664 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,03422374 0,04353145 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,03422374 0,04351628 ! formation of primary germ layer GO:0001704 37 31 0,000 0,03422374 0,04350112 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,03422374 0,04348597 ! endocytic vesicle GO:0030139 33 31 0,000 0,03422374 0,04347082 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,03422374 0,04345569 ! spermatid differentiation GO:0048515 32 31 0,000 0,03422374 0,04344057 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,03422374 0,04342546 ! neuron fate commitment GO:0048663 44 31 0,000 0,03422374 0,04341036 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,03422374 0,04339528 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,03422374 0,0433802 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,03422374 0,04336513 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,03422374 0,04335007 ! cell junction assembly GO:0034329 36 31 0,000 0,03422374 0,04333503 ! drug binding GO:0008144 34 31 0,000 0,03422374 0,04331999 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,03422374 0,04330496 ! peptide transport GO:0015833 36 31 0,000 0,03422374 0,04328995 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,03422374 0,04327494 ! peripheral nervous system development GO:0007422 35 31 0,000 0,03422374 0,04325995 ! I band GO:0031674 34 31 0,000 0,03422374 0,04324496 ! BMP signaling pathway GO:0030509 33 31 0,000 0,03422374 0,04322999 ! adult locomotory behavior GO:0008344 37 31 0,000 0,03422374 0,04321503 ! gene silencing GO:0016458 33 31 0,000 0,03422374 0,04320007 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,03530894 0,04455449 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,03530894 0,04453908 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,03530894 0,04452368 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,03530894 0,0445083 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,03530894 0,04449293 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,03530894 0,04447756 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,03530894 0,04446221 ! vesicle coat GO:0030120 39 32 0,000 0,03530894 0,04444687 ! cytokine production GO:0001816 32 32 0,000 0,03530894 0,04443153 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,03530894 0,04441621 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,03530894 0,0444009 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,03530894 0,0443856 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,03530894 0,04437031 ! oxygen binding GO:0019825 33 32 0,000 0,03530894 0,04435503 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,03530894 0,04433977 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,03530894 0,04432451 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,03530894 0,04430926 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,03530894 0,04429402 ! microtubule organizing center part GO:0044450 46 32 0,000 0,03530894 0,0442788 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,03639298 0,04562254 ! DNA helicase activity GO:0003678 55 33 0,000 0,03639298 0,04560687 ! neural tube development GO:0021915 37 33 0,000 0,03639298 0,04559121 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,03639298 0,04557555 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,03639298 0,04555991 ! organelle envelope lumen GO:0031970 46 33 0,000 0,03639298 0,04554428 ! regulation of cellular ketone metabolic process GO:0010565 46 33 0,000 0,03639298 0,04552867 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,03639298 0,04551306 ! NAD or NADH binding GO:0051287 36 33 0,000 0,03639298 0,04549746 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,03639298 0,04548187 ! B cell differentiation GO:0030183 37 33 0,000 0,03639298 0,0454663 ! aerobic respiration GO:0009060 35 33 0,000 0,03639298 0,04545073 ! embryonic organ development GO:0048568 41 33 0,000 0,03639298 0,04543518 ! placenta development GO:0001890 39 33 0,000 0,03639298 0,04541963 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,03639298 0,0454041 ! tissue remodeling GO:0048771 37 33 0,000 0,03639298 0,04538858 ! flagellum GO:0019861 34 33 0,000 0,03639298 0,04537307 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,03639298 0,04535756 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03639298 0,04534207 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,03639298 0,04532659 ! odontogenesis GO:0042476 39 34 0,000 0,03747586 0,04665936 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,03747586 0,04664344 ! lipid homeostasis GO:0055088 37 34 0,000 0,03747586 0,04662753 ! telencephalon development GO:0021537 36 34 0,000 0,03747586 0,04661164 ! clathrin coat GO:0030118 41 34 0,000 0,03747586 0,04659575 ! cell growth GO:0016049 36 34 0,000 0,03747586 0,04657987 ! protein polymerization GO:0051258 38 34 0,000 0,03747586 0,04656401 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,03747586 0,04654815 ! learning GO:0007612 51 34 0,000 0,03747586 0,04653231 ! keratinization GO:0031424 40 34 0,000 0,03747586 0,04651648 ! ovulation cycle process GO:0022602 35 34 0,000 0,03747586 0,04650066 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,03747586 0,04648485 ! steroid hormone receptor binding GO:0035258 44 34 0,000 0,03747586 0,04646905 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,03747586 0,04645326 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,03747586 0,04643748 ! amino acid binding GO:0016597 40 34 0,000 0,03747586 0,04642171 ! regulation of protein stability GO:0031647 35 34 0,000 0,03747586 0,04640595 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,03747586 0,0463902 ! glycogen metabolic process GO:0005977 48 34 0,000 0,03747586 0,04637447 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,03747586 0,04635874 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,03747586 0,04634303 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,03747586 0,04632732 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,03855758 0,04764839 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 53 35 0,000 0,03855758 0,04763225 ! response to estrogen stimulus GO:0043627 48 35 0,000 0,03855758 0,04761613 ! inner ear morphogenesis GO:0042472 46 35 0,000 0,03855758 0,04760001 ! MHC protein complex GO:0042611 50 35 0,000 0,03855758 0,04758391 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,03855758 0,04756782 ! vesicle lumen GO:0031983 38 35 0,000 0,03855758 0,04755174 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,03855758 0,04753567 ! mesenchymal cell development GO:0014031 40 35 0,000 0,03855758 0,04751961 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,03855758 0,04750356 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,03855758 0,04748752 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,03855758 0,0474715 ! regulation of proteolysis GO:0030162 37 35 0,000 0,03855758 0,04745548 ! ovulation cycle GO:0042698 37 35 0,000 0,03855758 0,04743947 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,03855758 0,04742348 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,03855758 0,0474075 ! collagen GO:0005581 54 35 0,000 0,03855758 0,04739152 ! glucan metabolic process GO:0044042 49 35 0,000 0,03855758 0,04737556 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,03855758 0,04735961 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,03855758 0,04734367 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,03855758 0,04732774 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,03855758 0,04731182 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,03855758 0,04729591 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,03855758 0,04728001 ! maintenance of protein location GO:0045185 45 35 0,000 0,03855758 0,04726413 ! polyol metabolic process GO:0019751 46 35 0,000 0,03855758 0,04724825 ! androgen receptor signaling pathway GO:0030521 47 35 0,000 0,03855758 0,04723239 ! cytokinesis GO:0000910 38 35 0,000 0,03855758 0,04721653 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,03855758 0,04720069 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,03963814 0,04850719 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,03963814 0,04849092 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,03963814 0,04847467 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,03963814 0,04845842 ! SMAD binding GO:0046332 39 36 0,000 0,03963814 0,04844219 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,03963814 0,04842596 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,03963814 0,04840975 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,03963814 0,04839355 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,03963814 0,04837736 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,03963814 0,04836118 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,03963814 0,04834501 ! nucleus organization GO:0006997 42 36 0,000 0,03963814 0,04832885 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,03963814 0,04831271 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,03963814 0,04829657 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,03963814 0,04828044 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,03963814 0,04826433 ! maintenance of location in cell GO:0051651 38 36 0,000 0,03963814 0,04824823 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,04071754 0,04954556 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,04071754 0,04952904 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,04071754 0,04951253 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,04071754 0,04949603 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,04071754 0,04947955 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,04071754 0,04946307 ! endoribonuclease activity GO:0004521 48 37 0,000 0,04071754 0,0494466 ! hindbrain development GO:0030902 43 37 0,000 0,04071754 0,04943015 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,04071754 0,04941371 ! pigmentation GO:0043473 51 37 0,000 0,04071754 0,04939727 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,04071754 0,04938085 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,04071754 0,04936444 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,04071754 0,04934804 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,04071754 0,04933165 ! sensory perception of taste GO:0050909 37 37 0,000 0,04071754 0,04931527 ! cell junction organization GO:0034330 44 37 0,000 0,04071754 0,0492989 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,04071754 0,04928255 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,04071754 0,0492662 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,04071754 0,04924987 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,04071754 0,04923354 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,04071754 0,04921723 ! coated pit GO:0005905 44 37 0,000 0,04071754 0,04920093 ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,04179579 0,0504871 ! regulation of translational initiation GO:0006446 50 38 0,000 0,04179579 0,05047039 ! negative regulation of binding GO:0051100 44 38 0,000 0,04179579 0,05045369 ! organic ether metabolic process GO:0018904 50 38 0,000 0,04179579 0,050437 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,04179579 0,05042032 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,04179579 0,05040365 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,04179579 0,050387 ! hydro-lyase activity GO:0016836 44 38 0,000 0,04179579 0,05037035 ! synapse organization GO:0050808 43 38 0,000 0,04179579 0,05035372 ! viral infectious cycle GO:0019058 40 38 0,000 0,04179579 0,05033709 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,04179579 0,05032048 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,04179579 0,05030388 ! organic anion transport GO:0015711 42 38 0,000 0,04179579 0,05028729 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,04179579 0,05027071 ! monosaccharide binding GO:0048029 41 38 0,000 0,04179579 0,05025414 ! muscle fiber development GO:0048747 42 38 0,000 0,04179579 0,05023758 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,04179579 0,05022103 ! phagocytosis GO:0006909 44 38 0,000 0,04179579 0,0502045 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,04179579 0,05018797 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,04179579 0,05017146 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,04179579 0,05015495 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,04179579 0,05013846 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,04179579 0,05012198 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,04179579 0,05010551 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,04179579 0,05008905 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,04287289 0,05136299 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,04287289 0,05134612 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,04287289 0,05132927 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,04287289 0,05131243 ! T cell differentiation GO:0030217 64 39 0,000 0,04287289 0,0512956 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,04287289 0,05127879 ! cell fate specification GO:0001708 55 39 0,000 0,04287289 0,05126198 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,04287289 0,05124518 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,04287289 0,0512284 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,04287289 0,05121162 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,04287289 0,05119486 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,04287289 0,05117811 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,04287289 0,05116137 ! amine receptor activity GO:0008227 48 39 0,000 0,04287289 0,05114464 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,04287289 0,05112792 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,04287289 0,05111121 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,04287289 0,05109451 ! double-strand break repair GO:0006302 70 39 0,000 0,04287289 0,05107782 ! pigment metabolic process GO:0042440 43 39 0,000 0,04287289 0,05106115 ! RNA modification GO:0009451 39 39 0,000 0,04287289 0,05104448 ! damaged DNA binding GO:0003684 51 40 0,000 0,04394883 0,05230843 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,04394883 0,05229137 ! peroxisomal membrane GO:0005778 44 40 0,000 0,04394883 0,05227432 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,04394883 0,05225728 ! positive regulation of cell development GO:0010720 43 40 0,000 0,04394883 0,05224025 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,04394883 0,05222323 ! biopolymer methylation GO:0043414 45 40 0,000 0,04394883 0,05220623 ! neuron migration GO:0001764 43 40 0,000 0,04394883 0,05218924 ! regulation of protein secretion GO:0050708 45 40 0,000 0,04394883 0,05217225 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,04394883 0,05215528 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,04394883 0,05213832 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,04394883 0,05212137 ! positive regulation of defense response GO:0031349 41 40 0,000 0,04394883 0,05210443 ! mammary gland development GO:0030879 47 40 0,000 0,04394883 0,0520875 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,04394883 0,05207059 ! neuropeptide binding GO:0042923 42 40 0,000 0,04394883 0,05205368 ! regulation of tube size GO:0035150 44 40 0,000 0,04394883 0,05203678 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,04394883 0,0520199 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,04394883 0,05200303 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,04394883 0,05198616 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,04394883 0,05196931 ! chromatin remodeling GO:0006338 44 40 0,000 0,04394883 0,05195247 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,04394883 0,05193564 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,04502362 0,05318852 ! Notch signaling pathway GO:0007219 46 41 0,000 0,04502362 0,05317131 ! keratin filament GO:0045095 44 41 0,000 0,04502362 0,0531541 ! peptide metabolic process GO:0006518 42 41 0,000 0,04502362 0,0531369 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,04502362 0,05311972 ! late endosome membrane GO:0031902 45 41 0,000 0,04502362 0,05310254 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,04502362 0,05308538 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,04502362 0,05306823 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,04502362 0,05305109 ! lamellipodium GO:0030027 56 41 0,000 0,04502362 0,05303396 ! glycolysis GO:0006096 43 41 0,000 0,04502362 0,05301684 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,04502362 0,05299973 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,04502362 0,05298263 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,04502362 0,05296555 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,04609726 0,05421109 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,04609726 0,05419362 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,04609726 0,05417616 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,04609726 0,05415871 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,04609726 0,05414127 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,04609726 0,05412385 ! nuclear export GO:0051168 46 42 0,000 0,04609726 0,05410643 ! developmental growth GO:0048589 45 42 0,000 0,04609726 0,05408903 ! structural constituent of muscle GO:0008307 46 42 0,000 0,04609726 0,05407164 ! mitochondrial transport GO:0006839 45 42 0,000 0,04609726 0,05405426 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,04609726 0,05403689 ! metal cluster binding GO:0051540 47 42 0,000 0,04609726 0,05401953 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,04609726 0,05400218 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,04609726 0,05398485 ! RNA catabolic process GO:0006401 49 43 0,000 0,04716975 0,05522312 ! ear morphogenesis GO:0042471 56 43 0,000 0,04716975 0,0552054 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,04716975 0,0551877 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,04716975 0,05517 ! cell recognition GO:0008037 51 43 0,000 0,04716975 0,05515232 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,04716975 0,05513465 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,04716975 0,05511699 ! gliogenesis GO:0042063 46 43 0,000 0,04716975 0,05509934 ! endosome transport GO:0016197 48 43 0,000 0,04716975 0,0550817 ! striated muscle contraction GO:0006941 45 43 0,000 0,04716975 0,05506408 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,04716975 0,05504646 ! antioxidant activity GO:0016209 53 43 0,000 0,04716975 0,05502886 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,04716975 0,05501127 ! activation of caspase activity GO:0006919 60 43 0,000 0,04716975 0,05499369 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,04716975 0,05497612 ! histone modification GO:0016570 45 43 0,000 0,04716975 0,05495856 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,04716975 0,05494101 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,04824109 0,05617092 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,04824109 0,056153 ! negative regulation of cell migration GO:0030336 53 44 0,000 0,04824109 0,05613509 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,04824109 0,05611719 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,04824109 0,0560993 ! chemokine activity GO:0008009 48 44 0,000 0,04824109 0,05608142 ! ruffle GO:0001726 50 44 0,000 0,04824109 0,05606355 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,04824109 0,0560457 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,04824109 0,05602786 ! cartilage development GO:0051216 48 44 0,000 0,04824109 0,05601002 ! membrane fusion GO:0006944 52 44 0,000 0,04824109 0,0559922 ! channel regulator activity GO:0016247 54 44 0,000 0,04824109 0,05597439 ! excretion GO:0007588 53 44 0,000 0,04824109 0,0559566 ! male sex differentiation GO:0046661 52 44 0,000 0,04824109 0,05593881 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,04824109 0,05592103 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,04824109 0,05590327 ! amino acid activation GO:0043038 45 44 0,000 0,04824109 0,05588552 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,04824109 0,05586778 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,04931128 0,05708904 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,04931128 0,05707093 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,04931128 0,05705283 ! organellar ribosome GO:0000313 46 45 0,000 0,04931128 0,05703474 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,04931128 0,05701666 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,04931128 0,05699859 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,04931128 0,05698054 ! transport vesicle GO:0030133 53 45 0,000 0,04931128 0,0569625 ! regulation of endocytosis GO:0030100 52 45 0,000 0,04931128 0,05694446 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,04931128 0,05692644 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,04931128 0,05690843 ! nuclear matrix GO:0016363 56 45 0,000 0,04931128 0,05689044 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,04931128 0,05687245 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,04931128 0,05685448 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,04931128 0,05683651 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,04931128 0,05681856 ! coated vesicle membrane GO:0030662 52 45 0,000 0,04931128 0,05680062 ! covalent chromatin modification GO:0016569 47 45 0,000 0,04931128 0,05678269 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,04931128 0,05676477 ! synaptosome GO:0019717 50 45 0,000 0,04931128 0,05674686 ! chemokine receptor binding GO:0042379 50 45 0,000 0,04931128 0,05672897 ! regulation of action potential GO:0001508 56 46 0,000 0,05038033 0,05794056 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,05038033 0,0579223 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,05038033 0,05790405 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,05038033 0,05788581 ! eye morphogenesis GO:0048592 57 46 0,000 0,05038033 0,05786758 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,05038033 0,05784937 ! methylation GO:0032259 51 46 0,000 0,05038033 0,05783117 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,05038033 0,05781297 ! regulation of ion transport GO:0043269 54 46 0,000 0,05038033 0,05779479 ! leukocyte migration GO:0050900 49 46 0,000 0,05038033 0,05777663 ! neuromuscular process GO:0050905 56 46 0,000 0,05038033 0,05775847 ! sulfotransferase activity GO:0008146 54 46 0,000 0,05038033 0,05774032 ! JNK cascade GO:0007254 48 46 0,000 0,05038033 0,05772219 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,05038033 0,05770406 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,05144823 0,05890871 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,05144823 0,05889023 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,05144823 0,05887175 ! microtubule binding GO:0008017 61 47 0,000 0,05144823 0,05885329 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,05144823 0,05883484 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,05144823 0,05881641 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,05144823 0,05879798 ! viral reproductive process GO:0022415 53 47 0,000 0,05144823 0,05877957 ! RNA elongation GO:0006354 52 47 0,000 0,05144823 0,05876116 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,05144823 0,05874277 ! mRNA binding GO:0003729 65 47 0,000 0,05144823 0,05872439 ! response to insulin stimulus GO:0032868 57 47 0,000 0,05144823 0,05870602 ! axon GO:0030424 53 48 0,000 0,05251499 0,05990453 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,05251499 0,0598858 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,05251499 0,05986709 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,05251499 0,05984839 ! protein homooligomerization GO:0051260 63 48 0,000 0,05251499 0,0598297 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,05251499 0,05981102 ! kinetochore GO:0000776 69 48 0,000 0,05251499 0,05979235 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,05251499 0,05977369 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,05251499 0,05975505 ! growth factor receptor binding GO:0070851 58 48 0,000 0,05251499 0,05973642 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,05251499 0,0597178 ! inner ear development GO:0048839 60 48 0,000 0,05251499 0,05969919 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,05251499 0,05968059 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,05251499 0,059662 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,05251499 0,05964343 ! B cell mediated immunity GO:0019724 53 48 0,000 0,05251499 0,05962486 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,05251499 0,05960631 ! regulation of cell shape GO:0008360 55 48 0,000 0,05251499 0,05958777 ! protein N-terminus binding GO:0047485 57 48 0,000 0,05251499 0,05956924 ! establishment of organelle localization GO:0051656 58 48 0,000 0,05251499 0,05955073 ! cell cortex part GO:0044448 54 48 0,000 0,05251499 0,05953222 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,05358061 0,06072136 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,05358061 0,0607025 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,05358061 0,06068366 ! response to temperature stimulus GO:0009266 57 49 0,000 0,05358061 0,06066482 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,05358061 0,060646 ! lipid modification GO:0030258 55 49 0,000 0,05358061 0,06062719 ! synaptic vesicle GO:0008021 56 49 0,000 0,05358061 0,06060839 ! regulation of gene expression, epigenetic GO:0040029 64 49 0,000 0,05358061 0,0605896 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,05358061 0,06057083 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,05358061 0,06055206 ! maintenance of location GO:0051235 62 49 0,000 0,05358061 0,06053331 ! negative regulation of cell motion GO:0051271 60 49 0,000 0,05358061 0,06051457 ! regulation of actin filament length GO:0030832 62 49 0,000 0,05358061 0,06049584 ! nuclear periphery GO:0034399 60 49 0,000 0,05358061 0,06047712 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,05358061 0,06045842 ! negative regulation of cytoskeleton organization GO:0051494 73 49 0,000 0,05358061 0,06043972 ! nucleotide-excision repair GO:0006289 53 49 0,000 0,05358061 0,06042104 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,05464508 0,06160237 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,05464508 0,06158334 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,05464508 0,06156432 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,05464508 0,06154531 ! glucose catabolic process GO:0006007 54 50 0,000 0,05464508 0,06152632 ! aging GO:0007568 92 50 0,000 0,05464508 0,06150733 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,05464508 0,06148836 ! heart morphogenesis GO:0003007 57 50 0,000 0,05464508 0,0614694 ! integrin binding GO:0005178 56 50 0,000 0,05464508 0,06145045 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,05464508 0,06143151 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,05570842 0,06260761 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,05570842 0,06258833 ! regulation of ossification GO:0030278 59 51 0,000 0,05570842 0,06256906 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,05570842 0,0625498 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,05570842 0,06253056 ! endocrine system development GO:0035270 55 51 0,000 0,05570842 0,06251132 ! germ cell development GO:0007281 56 51 0,000 0,05570842 0,0624921 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,05677061 0,06366406 ! regulation of cellular component size GO:0032535 66 52 0,000 0,05677061 0,0636445 ! carbohydrate transport GO:0008643 57 52 0,000 0,05677061 0,06362494 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,05677061 0,0636054 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,05677061 0,06358587 ! cell maturation GO:0048469 68 52 0,000 0,05677061 0,06356636 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,05677061 0,06354685 ! vesicle organization GO:0016050 59 52 0,000 0,05677061 0,06352736 ! kidney development GO:0001822 55 52 0,000 0,05677061 0,06350788 ! cellular component disassembly GO:0022411 69 52 0,000 0,05677061 0,06348841 ! cell redox homeostasis GO:0045454 57 52 0,000 0,05677061 0,06346895 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,05677061 0,06344951 ! lipid transporter activity GO:0005319 58 52 0,000 0,05677061 0,06343007 ! cytokine receptor activity GO:0004896 54 52 0,000 0,05677061 0,06341065 ! antiporter activity GO:0015297 53 52 0,000 0,05677061 0,06339124 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,05783167 0,06455628 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,05783167 0,06453653 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,05783167 0,0645168 ! basement membrane GO:0005604 55 53 0,000 0,05783167 0,06449707 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,05783167 0,06447736 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,05783167 0,06445766 ! viral reproduction GO:0016032 59 53 0,000 0,05783167 0,06443798 ! chloride transport GO:0006821 60 53 0,000 0,05783167 0,0644183 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,05783167 0,06439864 ! regulation of protein catabolic process GO:0042176 56 53 0,000 0,05783167 0,06437898 ! regulation of DNA replication GO:0006275 75 53 0,000 0,05783167 0,06435934 ! DNA catabolic process GO:0006308 57 53 0,000 0,05783167 0,06433972 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,05783167 0,0643201 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,05783167 0,0643005 ! single fertilization GO:0007338 58 53 0,000 0,05783167 0,06428091 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,05889159 0,06543909 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,05889159 0,06541916 ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,05889159 0,06539925 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,05889159 0,06537934 ! coated membrane GO:0048475 65 54 0,000 0,05889159 0,06535945 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,05889159 0,06533957 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,05889159 0,06531971 ! cellular defense response GO:0006968 61 54 0,000 0,05889159 0,06529985 ! gastrulation GO:0007369 62 54 0,000 0,05889159 0,06528001 ! dendrite GO:0030425 60 55 0,000 0,05995037 0,06643347 ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,05995037 0,06641329 ! respiratory chain GO:0070469 57 55 0,000 0,05995037 0,06639313 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,05995037 0,06637298 ! extracellular matrix organization GO:0030198 77 55 0,000 0,05995037 0,06635284 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,05995037 0,06633272 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,05995037 0,0663126 ! translation initiation factor activity GO:0003743 66 55 0,000 0,05995037 0,0662925 ! steroid hormone receptor signaling pathway GO:0030518 70 55 0,000 0,05995037 0,06627241 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,06100803 0,06742117 ! heat shock protein binding GO:0031072 62 56 0,000 0,06100803 0,06740075 ! late endosome GO:0005770 60 56 0,000 0,06100803 0,06738034 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,06100803 0,06735995 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,06100803 0,06733957 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,06100803 0,0673192 ! ribonuclease activity GO:0004540 67 56 0,000 0,06100803 0,06729884 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,06100803 0,0672785 ! mesoderm development GO:0007498 67 56 0,000 0,06100803 0,06725817 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,06100803 0,06723785 ! antigen processing and presentation GO:0019882 73 56 0,000 0,06100803 0,06721754 ! proton transport GO:0015992 59 56 0,000 0,06100803 0,06719725 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,06206454 0,06834031 ! chromosome segregation GO:0007059 92 57 0,000 0,06206454 0,06831969 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,06206454 0,06829908 ! diacylglycerol binding GO:0019992 65 57 0,000 0,06206454 0,06827848 ! B cell activation GO:0042113 63 57 0,000 0,06206454 0,0682579 ! small ribosomal subunit GO:0015935 58 57 0,000 0,06206454 0,06823733 ! detection of external stimulus GO:0009581 64 57 0,000 0,06206454 0,06821677 ! occluding junction GO:0070160 75 58 0,000 0,06311993 0,06935587 GO:0005923|tight junction, ! hydrogen transport GO:0006818 61 58 0,000 0,06311993 0,06933499 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,06311993 0,06931412 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,06311993 0,06929326 ! response to nutrient GO:0007584 68 58 0,000 0,06311993 0,06927241 ! large ribosomal subunit GO:0015934 64 58 0,000 0,06311993 0,06925158 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,06311993 0,06923076 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,06311993 0,06920995 ! myosin complex GO:0016459 64 58 0,000 0,06311993 0,06918915 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,06417418 0,07032364 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,06417418 0,07030253 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,06417418 0,07028142 ! actin filament organization GO:0007015 65 59 0,000 0,06417418 0,07026033 ! regulation of heart contraction GO:0008016 71 59 0,000 0,06417418 0,07023925 ! hexose catabolic process GO:0019320 64 59 0,000 0,06417418 0,07021818 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,06417418 0,07019712 ! response to steroid hormone stimulus GO:0048545 74 59 0,000 0,06417418 0,07017608 ! cell projection assembly GO:0030031 79 59 0,000 0,06417418 0,07015505 ! regulation of cellular response to stress GO:0080135 79 59 0,000 0,06417418 0,07013404 ! appendage morphogenesis GO:0035107 68 59 0,000 0,06417418 0,07011303 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,06417418 0,07009204 ! fertilization GO:0009566 65 59 0,000 0,06417418 0,07007106 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,06417418 0,07005009 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,06417418 0,07002914 ! adult behavior GO:0030534 72 59 0,000 0,06417418 0,0700082 ! organelle localization GO:0051640 70 59 0,000 0,06417418 0,06998727 ! positive regulation of secretion GO:0051047 66 60 0,000 0,0652273 0,07111453 ! molecular adaptor activity GO:0060090 73 60 0,000 0,0652273 0,07109328 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,0652273 0,07107204 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,0652273 0,07105082 ! copper ion binding GO:0005507 85 60 0,000 0,0652273 0,07102961 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,0652273 0,07100842 ! activation of immune response GO:0002253 72 60 0,000 0,0652273 0,07098723 ! cell cycle checkpoint GO:0000075 91 60 0,000 0,0652273 0,07096606 ! appendage development GO:0048736 69 60 0,000 0,0652273 0,0709449 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,0652273 0,07092376 ! secondary metabolic process GO:0019748 67 60 0,000 0,0652273 0,07090262 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,0662793 0,07202469 ! ear development GO:0043583 76 61 0,000 0,0662793 0,07200324 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,0662793 0,07198181 ! learning or memory GO:0007611 79 61 0,000 0,0662793 0,07196038 ! Ras GTPase binding GO:0017016 78 61 0,000 0,0662793 0,07193897 ! camera-type eye development GO:0043010 69 61 0,000 0,0662793 0,07191757 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,0662793 0,07189619 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,06733017 0,0730144 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,06733017 0,0729927 ! lysosomal membrane GO:0005765 69 62 0,000 0,06733017 0,07297102 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,06733017 0,07294935 ! nuclear pore GO:0005643 79 62 0,000 0,06733017 0,07292769 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,06733017 0,07290604 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,06733017 0,07288441 ! chloride channel activity GO:0005254 72 62 0,000 0,06733017 0,07286278 ! cell soma GO:0043025 68 62 0,000 0,06733017 0,07284118 ! microtubule motor activity GO:0003777 94 62 0,000 0,06733017 0,07281958 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 0,000 0,06733017 0,072798 ! focal adhesion GO:0005925 72 62 0,000 0,06733017 0,07277643 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,06733017 0,07275487 ! FAD binding GO:0050660 71 63 0,000 0,06837991 0,07386731 ! urogenital system development GO:0001655 75 63 0,000 0,06837991 0,07384544 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,06837991 0,07382359 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,06837991 0,07380175 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,06837991 0,07377992 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,06837991 0,0737581 ! regulation of immune effector process GO:0002697 81 63 0,000 0,06837991 0,0737363 ! respiratory tube development GO:0030323 92 64 0,000 0,06942852 0,07484493 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,06942852 0,07482282 ! tRNA processing GO:0008033 73 64 0,000 0,06942852 0,07480072 ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,06942852 0,07477864 ! adaptive immune response GO:0002250 70 64 0,000 0,06942852 0,07475657 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,06942852 0,07473451 ! neurotransmitter transport GO:0006836 72 64 0,000 0,06942852 0,07471246 ! regulation of actin cytoskeleton organization GO:0032956 93 64 0,000 0,06942852 0,07469043 ! nuclear hormone receptor binding GO:0035257 79 64 0,000 0,06942852 0,07466841 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,06942852 0,0746464 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,07047601 0,07575029 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,07047601 0,07572798 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,07047601 0,07570568 ! activation of MAPK activity GO:0000187 74 65 0,000 0,07047601 0,0756834 ! gonad development GO:0008406 71 65 0,000 0,07047601 0,07566112 ! acetyltransferase activity GO:0016407 73 65 0,000 0,07047601 0,07563886 ! protein import into nucleus GO:0006606 73 66 0,000 0,07152238 0,07673931 ! developmental maturation GO:0021700 85 66 0,000 0,07152238 0,07671675 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,07152238 0,0766942 ! tubulin binding GO:0015631 92 66 0,000 0,07152238 0,07667166 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,07152238 0,07664913 ! tube morphogenesis GO:0035239 84 66 0,000 0,07152238 0,07662662 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,07152238 0,07660413 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,07152238 0,07658164 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,07256763 0,07767803 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,07256763 0,07765524 ! nuclear import GO:0051170 74 67 0,000 0,07256763 0,07763247 ! response to peptide hormone stimulus GO:0043434 79 67 0,000 0,07256763 0,07760971 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,07256763 0,07758696 ! regulation of actin filament-based process GO:0032970 96 67 0,000 0,07256763 0,07756423 ! chloride ion binding GO:0031404 79 67 0,000 0,07256763 0,07754151 ! humoral immune response GO:0006959 75 67 0,000 0,07256763 0,0775188 ! amine binding GO:0043176 77 67 0,000 0,07256763 0,07749611 ! female pregnancy GO:0007565 78 67 0,000 0,07256763 0,07747343 ! extrinsic to membrane GO:0019898 75 67 0,000 0,07256763 0,07745076 ! anion channel activity GO:0005253 77 67 0,000 0,07256763 0,07742811 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,07256763 0,07740547 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,07361176 0,07849625 ! amine catabolic process GO:0009310 73 68 0,000 0,07361176 0,07847331 ! negative regulation of organelle organization GO:0010639 93 68 0,000 0,07361176 0,07845039 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,07361176 0,07842748 ! cell-substrate junction GO:0030055 78 68 0,000 0,07361176 0,07840458 ! respiratory system development GO:0060541 96 68 0,000 0,07361176 0,07838169 ! mRNA transport GO:0051028 88 69 0,000 0,07465476 0,07946909 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,07465476 0,07944591 ! small GTPase binding GO:0031267 86 69 0,000 0,07465476 0,07942274 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,07465476 0,07939958 ! sarcomere GO:0030017 74 69 0,000 0,07465476 0,07937644 ! exocytosis GO:0006887 76 69 0,000 0,07465476 0,07935331 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,07465476 0,0793302 GO:0060538|skeletal muscle organ development, ! nucleosome assembly GO:0006334 87 69 0,000 0,07465476 0,0793071 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,07465476 0,07928401 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,07465476 0,07926093 ! amine biosynthetic process GO:0009309 78 70 0,000 0,07569665 0,08034372 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,07569665 0,08032035 ! early endosome GO:0005769 104 70 0,000 0,07569665 0,080297 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,07569665 0,08027366 ! regulation of lipase activity GO:0060191 78 70 0,000 0,07569665 0,08025033 ! amino acid transport GO:0006865 76 70 0,000 0,07569665 0,08022701 ! chromatin assembly GO:0031497 88 70 0,000 0,07569665 0,08020371 ! hormone receptor binding GO:0051427 85 70 0,000 0,07569665 0,08018042 ! calcium channel activity GO:0005262 86 70 0,000 0,07569665 0,08015715 ! axon guidance GO:0007411 87 70 0,000 0,07569665 0,08013389 ! cell cortex GO:0005938 77 70 0,000 0,07569665 0,08011064 ! nuclear chromosome part GO:0044454 94 70 0,000 0,07569665 0,08008741 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,07673742 0,08116501 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,07673742 0,08114148 ! protein localization in nucleus GO:0034504 78 71 0,000 0,07673742 0,08111797 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,07673742 0,08109447 ! pore complex GO:0046930 89 72 0,000 0,07777707 0,08216935 ! response to hypoxia GO:0001666 84 72 0,000 0,07777707 0,08214556 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,07777707 0,08212179 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,07777707 0,08209802 ! regulation of lyase activity GO:0051339 85 72 0,000 0,07777707 0,08207427 ! acute inflammatory response GO:0002526 91 72 0,000 0,07777707 0,08205054 ! apical junction complex GO:0043296 90 72 0,000 0,07777707 0,08202682 ! phospholipase activity GO:0004620 99 72 0,000 0,07777707 0,08200311 ! membrane raft GO:0045121 81 72 0,000 0,07777707 0,08197942 ! regulation of neurological system process GO:0031644 91 72 0,000 0,07777707 0,08195574 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,07777707 0,08193207 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,07881561 0,08300212 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,07881561 0,08297817 ! protein transporter activity GO:0008565 80 73 0,000 0,07881561 0,08295423 ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,07881561 0,0829303 ! exopeptidase activity GO:0008238 81 73 0,000 0,07881561 0,08290639 ! digestion GO:0007586 81 73 0,000 0,07881561 0,08288249 ! regulation of Rho protein signal transduction GO:0035023 88 73 0,000 0,07881561 0,0828586 ! cell-matrix adhesion GO:0007160 102 74 0,000 0,07985304 0,08392506 ! response to oxygen levels GO:0070482 86 74 0,000 0,07985304 0,08390089 ! potassium channel complex GO:0034705 84 74 0,000 0,07985304 0,08387673 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,07985304 0,08385259 ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,07985304 0,08382846 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,07985304 0,08380434 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,07985304 0,08378024 ! blood coagulation GO:0007596 90 74 0,000 0,07985304 0,08375615 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,07985304 0,08373207 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,07985304 0,08370801 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,07985304 0,08368397 ! cell projection part GO:0044463 80 74 0,000 0,07985304 0,08365993 ! regulation of DNA binding GO:0051101 94 75 0,000 0,08088935 0,08472132 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,08088935 0,084697 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,08088935 0,0846727 ! regulation of blood pressure GO:0008217 82 75 0,000 0,08088935 0,08464841 ! transcription initiation GO:0006352 84 75 0,000 0,08088935 0,08462413 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,08088935 0,08459987 ! neuropeptide signaling pathway GO:0007218 85 76 0,000 0,08192455 0,085658 ! defense response to bacterium GO:0042742 81 76 0,000 0,08192455 0,08563346 ! regulation of lipid metabolic process GO:0019216 98 76 0,000 0,08192455 0,08560893 ! cell leading edge GO:0031252 97 76 0,000 0,08192455 0,08558441 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,08192455 0,08555991 ! condensed chromosome GO:0000793 106 76 0,000 0,08192455 0,08553542 ! protein-DNA complex GO:0032993 93 76 0,000 0,08192455 0,08551095 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,08192455 0,08548649 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,08192455 0,08546204 ! cytosolic ribosome GO:0022626 82 76 0,000 0,08192455 0,08543761 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,08192455 0,08541319 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,08295864 0,08646661 ! nucleosome organization GO:0034728 96 77 0,000 0,08295864 0,08644191 ! alcohol catabolic process GO:0046164 84 77 0,000 0,08295864 0,08641723 ! vacuolar membrane GO:0005774 86 77 0,000 0,08295864 0,08639256 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,08295864 0,0863679 ! regulation of Ras GTPase activity GO:0032318 88 77 0,000 0,08295864 0,08634326 ! establishment of RNA localization GO:0051236 97 77 0,000 0,08295864 0,08631863 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! myofibril GO:0030016 82 77 0,000 0,08295864 0,08629402 ! protein oligomerization GO:0051259 93 77 0,000 0,08295864 0,08626942 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,08399162 0,08731874 ! endonuclease activity GO:0004519 111 78 0,000 0,08399162 0,08729386 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,08399162 0,087269 ! inorganic anion transport GO:0015698 87 78 0,000 0,08399162 0,08724415 ! regulation of protein transport GO:0051223 85 78 0,000 0,08399162 0,08721931 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,08399162 0,08719449 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,08399162 0,08716969 ! carboxylesterase activity GO:0004091 93 78 0,000 0,08399162 0,08714489 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,08399162 0,08712012 ! contractile fiber part GO:0044449 83 78 0,000 0,08399162 0,08709535 ! RNA localization GO:0006403 99 79 0,000 0,0850235 0,0881403 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,0850235 0,08811526 ! vitamin metabolic process GO:0006766 86 79 0,000 0,0850235 0,08809024 ! T cell activation GO:0042110 120 79 0,000 0,0850235 0,08806522 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,0850235 0,08804023 ! phosphoinositide binding GO:0035091 99 79 0,000 0,0850235 0,08801524 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,08605426 0,08905701 ! eye development GO:0001654 93 80 0,000 0,08605426 0,08903175 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,08605426 0,08900651 ! rhythmic process GO:0048511 90 80 0,000 0,08605426 0,08898128 ! regulation of catabolic process GO:0009894 87 80 0,000 0,08605426 0,08895607 ! SH3 domain binding GO:0017124 95 80 0,000 0,08605426 0,08893086 ! hemostasis GO:0007599 96 80 0,000 0,08605426 0,08890568 ! chromosome, centromeric region GO:0000775 119 80 0,000 0,08605426 0,08888051 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,08605426 0,08885535 ! cell-substrate adhesion GO:0031589 109 80 0,000 0,08605426 0,08883021 ! rRNA processing GO:0006364 84 80 0,000 0,08605426 0,08880508 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,08708392 0,08984224 ! vacuolar part GO:0044437 91 81 0,000 0,08708392 0,08981684 ! ossification GO:0001503 111 82 0,000 0,08811248 0,09085198 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,08811248 0,09082631 ! forebrain development GO:0030900 93 82 0,000 0,08811248 0,09080066 ! external side of plasma membrane GO:0009897 105 82 0,000 0,08811248 0,09077501 ! cellular respiration GO:0045333 85 82 0,000 0,08811248 0,09074938 ! heparin binding GO:0008201 108 82 0,000 0,08811248 0,09072377 ! microtubule-based movement GO:0007018 119 83 0,000 0,08913993 0,09175577 ! nuclear speck GO:0016607 99 83 0,000 0,08913993 0,09172989 ! rRNA metabolic process GO:0016072 88 83 0,000 0,08913993 0,09170402 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,08913993 0,09167817 GO:0070035|purine NTP-dependent helicase activity, ! regulation of cell adhesion GO:0030155 98 83 0,000 0,08913993 0,09165233 ! regulation of T cell activation GO:0050863 104 83 0,000 0,08913993 0,0916265 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,08913993 0,09160069 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,08913993 0,0915749 ! contractile fiber GO:0043292 88 83 0,000 0,08913993 0,09154912 ! bone development GO:0060348 112 83 0,000 0,08913993 0,09152335 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,08913993 0,0914976 ! regulation of membrane potential GO:0042391 98 83 0,000 0,08913993 0,09147186 ! cilium GO:0005929 88 83 0,000 0,08913993 0,09144614 ! regulation of DNA metabolic process GO:0051052 139 84 0,000 0,09016628 0,09247303 ! regulation of defense response GO:0031347 98 84 0,000 0,09016628 0,09244704 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,09016628 0,09242107 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,09016628 0,09239511 ! DNA recombination GO:0006310 147 84 0,000 0,09016628 0,09236916 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,09119153 0,09339323 ! monooxygenase activity GO:0004497 92 85 0,000 0,09119153 0,09336702 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,09119153 0,09334082 ! protein binding, bridging GO:0030674 104 85 0,000 0,09119153 0,09331464 ! negative regulation of transport GO:0051051 98 86 0,000 0,09221567 0,09433617 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,09221567 0,09430972 ! Golgi vesicle transport GO:0048193 98 86 0,000 0,09221567 0,09428329 ! lipase activity GO:0016298 114 86 0,000 0,09221567 0,09425687 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,09221567 0,09423047 ! adherens junction GO:0005912 100 86 0,000 0,09221567 0,09420408 ! leukocyte differentiation GO:0002521 118 87 0,000 0,09323872 0,09522252 ! pigment granule GO:0048770 101 87 0,000 0,09323872 0,09519587 GO:0042470|melanosome, ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,09323872 0,09516924 ! organelle outer membrane GO:0031968 102 88 0,000 0,09426067 0,09618543 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,09426067 0,09615854 ! growth factor binding GO:0019838 102 88 0,000 0,09426067 0,09613165 ! protein processing GO:0016485 100 88 0,000 0,09426067 0,09610479 ! gland development GO:0048732 108 89 0,000 0,09528152 0,09711847 ! ATP metabolic process GO:0046034 100 90 0,000 0,09630128 0,09813047 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,09630128 0,09810306 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,09630128 0,09807567 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,09630128 0,0980483 ! sterol metabolic process GO:0016125 102 90 0,000 0,09630128 0,09802095 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,09630128 0,0979936 ! anion binding GO:0043168 104 90 0,000 0,09630128 0,09796628 ! amine transport GO:0015837 97 90 0,000 0,09630128 0,09793896 ! response to virus GO:0009615 109 90 0,000 0,09630128 0,09791167 ! outer membrane GO:0019867 104 90 0,000 0,09630128 0,09788439 ! extracellular matrix part GO:0044420 111 90 0,000 0,09630128 0,09785712 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,09731994 0,0988647 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,09731994 0,09883718 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,09731994 0,09880967 ! sulfur metabolic process GO:0006790 98 91 0,000 0,09731994 0,09878218 ! sex differentiation GO:0007548 103 91 0,000 0,09731994 0,0987547 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 0,000 0,09731994 0,09872724 ! hormone metabolic process GO:0042445 107 91 0,000 0,09731994 0,09869979 ! regulation of protein localization GO:0032880 99 91 0,000 0,09731994 0,09867236 ! detection of stimulus GO:0051606 100 91 0,000 0,09731994 0,09864494 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,09833751 0,09964868 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,09833751 0,099621 ! regulation of cellular component biogenesis GO:0044087 115 92 0,000 0,09833751 0,09959335 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,09833751 0,09956571 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,09833751 0,09953808 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,09833751 0,09951047 ! regulation of GTPase activity GO:0043087 105 92 0,000 0,09833751 0,09948287 ! extracellular structure organization GO:0043062 119 92 0,000 0,09833751 0,09945529 ! protein import GO:0017038 102 93 0,000 0,09935399 0,10045547 ! regulation of cytoskeleton organization GO:0051493 133 93 0,000 0,09935399 0,10042764 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,09935399 0,10039982 ! response to nutrient levels GO:0031667 105 93 0,000 0,09935399 0,10037201 ! Ras protein signal transduction GO:0007265 118 93 0,000 0,09935399 0,10034422 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,10036937 0,10134167 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,10036937 0,10131363 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,10036937 0,10128561 GO:0060429|epithelium development, ! anchoring junction GO:0070161 108 94 0,000 0,10036937 0,10125759 ! neurotransmitter binding GO:0042165 105 94 0,000 0,10036937 0,1012296 ! DNA packaging GO:0006323 113 94 0,000 0,10036937 0,10120162 ! homophilic cell adhesion GO:0007156 107 95 0,000 0,10138366 0,10219608 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,10138366 0,10216785 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,10138366 0,10213963 ! protein localization in organelle GO:0033365 104 95 0,000 0,10138366 0,10211143 ! Wnt receptor signaling pathway GO:0016055 121 95 0,000 0,10138366 0,10208325 ! immune effector process GO:0002252 110 95 0,000 0,10138366 0,10205508 ! apical plasma membrane GO:0016324 105 95 0,000 0,10138366 0,10202693 ! translational elongation GO:0006414 104 96 0,000 0,10239687 0,10301814 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,10239687 0,10298974 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,10239687 0,10296135 ! receptor complex GO:0043235 131 96 0,000 0,10239687 0,10293298 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,10239687 0,10290462 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,10239687 0,10287628 ! electron transport chain GO:0022900 104 97 0,000 0,10340899 0,10386453 ! microtubule associated complex GO:0005875 135 97 0,000 0,10340899 0,10383594 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,10340899 0,10380737 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,10340899 0,10377881 ! carboxylic acid binding GO:0031406 108 97 0,000 0,10340899 0,10375027 ! protein maturation GO:0051604 109 97 0,000 0,10340899 0,10372174 ! intermediate filament GO:0005882 102 98 0,000 0,10442002 0,10470704 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,10442002 0,10467827 ! cell fate commitment GO:0045165 118 98 0,000 0,10442002 0,10464951 ! negative regulation of cellular component organization GO:0051129 132 99 0,000 0,10542996 0,10563265 ! hormone activity GO:0005179 113 99 0,000 0,10542996 0,10560365 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,10542996 0,10557466 ! unfolded protein binding GO:0051082 118 100 0,000 0,10643882 0,10655566 ! nuclear chromosome GO:0000228 127 100 0,000 0,10643882 0,10652642 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,10643882 0,10649721 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 0,000 0,10643882 0,10646801 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,10643882 0,10643882