pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/55605-6-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 5,000 5,583E-11 1,364E-07 ! polyol catabolic process GO:0046174 9 5 2,000 1,422E-08 1,737E-05 GO:0019405|alditol catabolic process, ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 4,041E-07 3,291E-04 ! fructose metabolic process GO:0006000 25 16 2,000 7,894E-07 4,821E-04 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 1,247E-06 6,094E-04 ! negative regulation of kinase activity GO:0033673 145 70 3,000 1,322E-06 5,382E-04 ! negative regulation of transferase activity GO:0051348 155 74 3,000 1,653E-06 5,77E-04 ! alditol metabolic process GO:0019400 44 26 2,000 3,636E-06 1,11E-03 ! sperm motility GO:0030317 37 28 2,000 4,574E-06 1,242E-03 ! hexose biosynthetic process GO:0019319 53 32 2,000 6,903E-06 1,686E-03 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 9,905E-06 2,2E-03 ! alcohol biosynthetic process GO:0046165 65 42 2,000 1,585E-05 3,227E-03 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 1,000 1,942E-05 3,649E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 1,954E-05 3,41E-03 ! polyol metabolic process GO:0019751 77 45 2,000 1,954E-05 3,183E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 2,089E-05 3,19E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 2,716E-05 3,903E-03 ! response to UV GO:0009411 120 55 2,000 3,584E-05 4,865E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 3,619E-05 4,653E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 4,649E-05 5,679E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 5,808E-05 6,756E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 5,808E-05 6,449E-03 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 1,000 5,808E-05 6,169E-03 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 1,000 5,808E-05 5,912E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 6,776E-05 6,622E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 7,079E-05 6,651E-03 ! keratinocyte proliferation GO:0043616 19 11 1,000 7,093E-05 6,418E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 8,038E-05 7,014E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 8,038E-05 6,772E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 8,505E-05 6,926E-03 ! regulation of caspase activity GO:0043281 136 74 2,000 8,723E-05 6,874E-03 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 9,82E-05 7,497E-03 ! positive regulation of ligase activity GO:0051351 130 77 2,000 9,82E-05 7,27E-03 ! positive regulation of cell growth GO:0030307 24 13 1,000 1,004E-04 7,217E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 1,06E-04 7,398E-03 ! negative regulation of caspase activity GO:0043154 23 14 1,000 1,171E-04 7,946E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 1,171E-04 7,732E-03 ! regulation of peptidase activity GO:0052547 150 82 2,000 1,184E-04 7,613E-03 ! regulation of ligase activity GO:0051340 147 84 2,000 1,272E-04 7,968E-03 ! positive regulation of GTPase activity GO:0043547 43 15 1,000 1,35E-04 8,246E-03 ! alcohol catabolic process GO:0046164 142 87 2,000 1,412E-04 8,411E-03 ! positive regulation of cell size GO:0045793 29 16 1,000 1,542E-04 8,969E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,542E-04 8,76E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 1,72E-04 9,549E-03 GO:0010498|proteasomal protein catabolic process, ! negative regulation of peptidase activity GO:0010466 28 17 1,000 1,746E-04 9,48E-03 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 1,746E-04 9,274E-03 GO:0031114|regulation of microtubule depolymerization, ! regulation of protein binding GO:0043393 33 17 1,000 1,746E-04 9,077E-03 ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 1,775E-04 9,035E-03 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 1,963E-04 9,787E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 2,008E-04 9,81E-03 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 1,000 2,192E-04 0,01050203 ! skin development GO:0043588 42 20 1,000 2,434E-04 0,01143615 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 2,434E-04 0,01122038 ! cellular response to unfolded protein GO:0034620 35 20 1,000 2,434E-04 0,01101259 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of B cell activation GO:0050871 42 22 1,000 2,955E-04 0,01312636 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 3,234E-04 0,01410945 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 3,526E-04 0,01511104 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 3,526E-04 0,01485051 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 3,829E-04 0,01585667 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 3,829E-04 0,0155924 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 3,829E-04 0,01533678 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 4,146E-04 0,01633493 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 4,146E-04 0,01607564 ! neural tube closure GO:0001843 58 26 1,000 4,146E-04 0,01582446 GO:0060606|tube closure, ! tube lumen formation GO:0035148 59 27 1,000 4,474E-04 0,0168152 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 4,815E-04 0,01782128 ! fat cell differentiation GO:0045444 57 28 1,000 4,815E-04 0,01755529 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 5,167E-04 0,01856483 ! primary neural tube formation GO:0014020 61 29 1,000 5,167E-04 0,01829577 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 5,533E-04 0,01930847 ! regulation of B cell activation GO:0050864 55 30 1,000 5,533E-04 0,01903652 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 5,91E-04 0,0200521 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 5,91E-04 0,01977741 ! spindle organization GO:0007051 50 32 1,000 6,299E-04 0,02079564 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 7,978E-04 0,02598562 ! regulation of microtubule-based process GO:0032886 86 37 1,000 8,427E-04 0,02708928 ! meiosis I GO:0007127 74 38 1,000 8,889E-04 0,02820229 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 8,889E-04 0,02784072 ! neural tube formation GO:0001841 79 38 1,000 8,889E-04 0,02748831 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 9,363E-04 0,02859111 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! embryonic epithelial tube formation GO:0001838 85 41 1,000 1,035E-03 0,03120309 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 1,191E-03 0,03548096 ! keratinocyte differentiation GO:0030216 81 45 1,000 1,245E-03 0,03665711 ! neural tube development GO:0021915 91 47 1,000 1,358E-03 0,03949244 ! positive regulation of cell cycle GO:0045787 96 48 1,000 1,416E-03 0,04069498 ! response to calcium ion GO:0051592 94 49 1,000 1,475E-03 0,04190278 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 1,475E-03 0,04142114 ! activation of caspase activity GO:0006919 95 50 1,000 1,535E-03 0,04262561 ! epidermal cell differentiation GO:0009913 87 50 1,000 1,535E-03 0,04214667 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 1,66E-03 0,04504896 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 1,66E-03 0,04455391 ! positive regulation of growth GO:0045927 96 53 1,000 1,723E-03 0,04576447 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 1,723E-03 0,04527238 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 1,000 1,723E-03 0,04479076 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 1,788E-03 0,04599032 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 1,922E-03 0,0489065 ! positive regulation of caspase activity GO:0043280 108 57 1,000 1,99E-03 0,05012584 GO:0010952|positive regulation of peptidase activity, ! regulation of endocytosis GO:0030100 104 60 1,000 2,202E-03 0,05490325 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 2,35E-03 0,05797947 ! negative regulation of cell growth GO:0030308 142 67 1,000 2,737E-03 0,06686896 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 2,737E-03 0,06620689 ! negative regulation of ligase activity GO:0051352 116 68 1,000 2,818E-03 0,06749522 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of cell size GO:0045792 144 69 1,000 2,9E-03 0,06878503 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 3,327E-03 0,07814714 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 3,415E-03 0,07946564 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 3,596E-03 0,08287849 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 3,688E-03 0,08420324 ! negative regulation of organelle organization GO:0010639 181 80 1,000 3,875E-03 0,08765737 ! meiosis GO:0007126 143 81 1,000 3,97E-03 0,0889872 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 3,97E-03 0,08817823 ! protein import into nucleus GO:0006606 174 82 1,000 4,067E-03 0,08950327 ! meiotic cell cycle GO:0051321 144 82 1,000 4,067E-03 0,08870414 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 4,164E-03 0,09002446 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 4,164E-03 0,08923477 ! response to metal ion GO:0010038 158 84 1,000 4,263E-03 0,09055044 ! negative regulation of growth GO:0045926 168 85 1,000 4,362E-03 0,09186611 ! positive regulation of cell activation GO:0050867 161 86 1,000 4,463E-03 0,09318171 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 159 87 1,000 4,564E-03 0,0944972 ! cellular respiration GO:0045333 143 88 1,000 4,667E-03 0,09581253 ! tube morphogenesis GO:0035239 194 89 1,000 4,771E-03 0,09712766 ! protein localization in nucleus GO:0034504 192 89 1,000 4,771E-03 0,09632495 ! response to inorganic substance GO:0010035 173 90 1,000 4,876E-03 0,09763563 ! positive regulation of protein modification process GO:0031401 156 90 1,000 4,876E-03 0,09684185 ! response to unfolded protein GO:0006986 139 90 1,000 4,876E-03 0,09606086 ! response to protein stimulus GO:0051789 158 96 1,000 5,527E-03 0,10802541 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 5,755E-03 0,11157399 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 5,755E-03 0,11069545 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 5,755E-03 0,10983064 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 5,755E-03 0,10897924 ! positive regulation of helicase activity GO:0051096 12 5 0,000 5,755E-03 0,10814094 ! neuron fate determination GO:0048664 7 5 0,000 5,755E-03 0,10731544 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,755E-03 0,10650244 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 5,755E-03 0,10570167 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 5,755E-03 0,10491285 ! polyol transport GO:0015791 12 5 0,000 5,755E-03 0,10413572 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 5,755E-03 0,10337002 ! response to superoxide GO:0000303 10 5 0,000 5,755E-03 0,10261549 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,755E-03 0,1018719 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 5,755E-03 0,10113901 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 5,755E-03 0,10041659 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 5,755E-03 0,09970441 ! female meiosis GO:0007143 10 5 0,000 5,755E-03 0,09900227 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 5,755E-03 0,09830995 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 5,755E-03 0,09762724 ! hypothalamus development GO:0021854 9 5 0,000 5,755E-03 0,09695395 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 5,755E-03 0,09628988 ! cobalt ion transport GO:0006824 11 5 0,000 5,755E-03 0,09563484 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 5,755E-03 0,09498866 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 5,755E-03 0,09435116 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 5,755E-03 0,09372215 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 5,755E-03 0,09310147 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 5,755E-03 0,09248896 ! embryonic camera-type eye development GO:0031076 12 5 0,000 5,755E-03 0,09188446 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 5,755E-03 0,09128781 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,755E-03 0,09069885 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 5,755E-03 0,09011745 ! transposition GO:0032196 9 5 0,000 5,755E-03 0,08954345 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 5,755E-03 0,08897672 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 5,755E-03 0,08841712 ! negative chemotaxis GO:0050919 16 5 0,000 5,755E-03 0,08786451 ! positive regulation of histone modification GO:0031058 6 5 0,000 5,755E-03 0,08731877 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,755E-03 0,08677977 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 5,755E-03 0,08624738 ! behavioral response to pain GO:0048266 10 5 0,000 5,755E-03 0,08572148 ! clathrin coat assembly GO:0048268 15 5 0,000 5,755E-03 0,08520195 ! Notch receptor processing GO:0007220 11 5 0,000 5,755E-03 0,08468869 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,755E-03 0,08418157 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 5,755E-03 0,08368049 ! micturition GO:0060073 9 5 0,000 5,755E-03 0,08318534 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 5,755E-03 0,08269601 ! copulation GO:0007620 9 5 0,000 5,755E-03 0,08221241 ! glial cell fate commitment GO:0021781 14 5 0,000 5,755E-03 0,08173443 ! protein maturation by protein folding GO:0022417 14 5 0,000 5,755E-03 0,08126198 ! bioluminescence GO:0008218 9 5 0,000 5,755E-03 0,08079496 ! spermidine metabolic process GO:0008216 7 5 0,000 5,755E-03 0,08033327 ! regulation of potassium ion transport GO:0043266 10 5 0,000 5,755E-03 0,07987683 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 5,755E-03 0,07942555 ! apoptotic cell clearance GO:0043277 23 5 0,000 5,755E-03 0,07897934 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 5,755E-03 0,07853811 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 5,755E-03 0,07810179 ! lipoprotein particle clearance GO:0034381 10 5 0,000 5,755E-03 0,07767029 ! grooming behavior GO:0007625 6 5 0,000 5,755E-03 0,07724353 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 5,755E-03 0,07682143 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 5,755E-03 0,07640393 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 5,755E-03 0,07599093 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,755E-03 0,07558238 ! response to protozoan GO:0001562 13 5 0,000 5,755E-03 0,07517819 ! positive regulation of glycolysis GO:0045821 13 5 0,000 5,755E-03 0,07477831 ! lymph vessel development GO:0001945 10 5 0,000 5,755E-03 0,07438266 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 5,755E-03 0,07399117 ! endochondral ossification GO:0001958 17 5 0,000 5,755E-03 0,07360378 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 5,755E-03 0,07322043 ! single strand break repair GO:0000012 8 5 0,000 5,755E-03 0,07284105 ! parathyroid gland development GO:0060017 14 5 0,000 5,755E-03 0,07246558 ! anagen GO:0042640 7 5 0,000 5,755E-03 0,07209396 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 5,755E-03 0,07172613 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 5,755E-03 0,07136204 ! cytokine secretion GO:0050663 15 5 0,000 5,755E-03 0,07100163 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 5,755E-03 0,07064484 ! ceramide catabolic process GO:0046514 7 5 0,000 5,755E-03 0,07029161 ! skeletal myofibril assembly GO:0014866 12 5 0,000 5,755E-03 0,0699419 ! smooth muscle tissue development GO:0048745 32 5 0,000 5,755E-03 0,06959565 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,755E-03 0,06925282 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 5,755E-03 0,06891334 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 5,755E-03 0,06857718 ! cardiac muscle fiber development GO:0048739 12 5 0,000 5,755E-03 0,06824428 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,755E-03 0,0679146 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 5,755E-03 0,06758809 ! neutrophil mediated immunity GO:0002446 7 5 0,000 5,755E-03 0,0672647 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 5,755E-03 0,06694439 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 5,755E-03 0,06662712 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 5,755E-03 0,06631284 ! glycine biosynthetic process GO:0006545 7 5 0,000 5,755E-03 0,06600151 ! microvillus organization GO:0032528 8 5 0,000 5,755E-03 0,06569309 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 5,755E-03 0,06538755 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 5,755E-03 0,06508483 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 5,755E-03 0,06478489 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 5,755E-03 0,06448772 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 5,755E-03 0,06419325 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 5,755E-03 0,06390146 ! polyol biosynthetic process GO:0046173 6 5 0,000 5,755E-03 0,06361232 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 5,755E-03 0,06332578 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,755E-03 0,0630418 ! muscle cell migration GO:0014812 8 5 0,000 5,755E-03 0,06276037 ! mitochondrial fission GO:0000266 8 5 0,000 5,755E-03 0,06248143 ! sister chromatid cohesion GO:0007062 15 5 0,000 5,755E-03 0,06220497 ! response to tumor necrosis factor GO:0034612 10 5 0,000 5,755E-03 0,06193093 ! mRNA transcription GO:0009299 10 5 0,000 5,755E-03 0,06165931 ! nerve growth factor processing GO:0032455 9 5 0,000 5,755E-03 0,06139005 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 5,755E-03 0,06112314 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 5,755E-03 0,06085854 ! anaerobic glycolysis GO:0019642 6 5 0,000 5,755E-03 0,06059622 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 5,755E-03 0,06033615 ! monocyte activation GO:0042117 10 5 0,000 5,755E-03 0,0600783 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 5,755E-03 0,05982265 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 5,755E-03 0,05956916 ! response to food GO:0032094 6 5 0,000 5,755E-03 0,05931782 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 5,755E-03 0,05906858 ! positive regulation of transporter activity GO:0032411 8 5 0,000 5,755E-03 0,05882143 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 5,755E-03 0,05857634 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,755E-03 0,05833329 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 5,755E-03 0,05809224 ! forebrain neuron development GO:0021884 13 5 0,000 5,755E-03 0,05785318 ! lipoprotein catabolic process GO:0042159 11 5 0,000 5,755E-03 0,05761607 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 5,755E-03 0,05738091 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 5,755E-03 0,05714765 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 5,755E-03 0,05691628 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,755E-03 0,05668678 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 5,755E-03 0,05645913 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 5,755E-03 0,05623329 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 5,755E-03 0,05600925 ! lipid glycosylation GO:0030259 7 5 0,000 5,755E-03 0,05578699 ! nucleobase transport GO:0015851 6 5 0,000 5,755E-03 0,05556649 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,755E-03 0,05534773 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 5,755E-03 0,05513068 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 5,755E-03 0,05491532 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 5,755E-03 0,05470164 ! basic amino acid transport GO:0015802 12 5 0,000 5,755E-03 0,05448962 ! cellular glucose homeostasis GO:0001678 6 5 0,000 5,755E-03 0,05427924 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 5,755E-03 0,05407047 ! actin nucleation GO:0045010 11 5 0,000 5,755E-03 0,0538633 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,755E-03 0,05365772 ! depurination GO:0045007 5 5 0,000 5,755E-03 0,0534537 ! depyrimidination GO:0045008 10 5 0,000 5,755E-03 0,05325122 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,755E-03 0,05305027 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,755E-03 0,05285084 ! G2/M transition checkpoint GO:0031576 8 5 0,000 5,755E-03 0,05265289 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 5,755E-03 0,05245643 ! zinc ion homeostasis GO:0055069 9 5 0,000 5,755E-03 0,05226142 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 5,755E-03 0,05206786 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 5,755E-03 0,05187573 ! forebrain morphogenesis GO:0048853 13 5 0,000 5,755E-03 0,05168501 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 5,755E-03 0,05149569 ! activated T cell proliferation GO:0050798 16 5 0,000 5,755E-03 0,05130775 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 5,755E-03 0,05112117 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 5,755E-03 0,05093595 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,755E-03 0,05075207 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,755E-03 0,0505695 ! gamma-delta T cell activation GO:0046629 6 5 0,000 5,755E-03 0,05038825 ! response to arsenic GO:0046685 11 5 0,000 5,755E-03 0,05020829 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 5,755E-03 0,05002962 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 5,755E-03 0,04985221 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 5,755E-03 0,04967605 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 5,755E-03 0,04950113 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 5,755E-03 0,04932745 ! response to mercury ion GO:0046689 8 5 0,000 5,755E-03 0,04915497 ! response to cadmium ion GO:0046686 7 5 0,000 5,755E-03 0,0489837 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 5,755E-03 0,04881362 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 5,755E-03 0,04864471 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 5,755E-03 0,04847697 ! bile acid biosynthetic process GO:0006699 7 5 0,000 5,755E-03 0,04831039 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,755E-03 0,04814494 ! ganglioside catabolic process GO:0006689 12 5 0,000 5,755E-03 0,04798062 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 5,755E-03 0,04781742 ! decidualization GO:0046697 11 5 0,000 5,755E-03 0,04765533 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 5,755E-03 0,04749433 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 5,755E-03 0,04733442 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 5,755E-03 0,04717558 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 5,755E-03 0,0470178 ! embryonic cleavage GO:0040016 6 5 0,000 5,755E-03 0,04686107 ! peroxisome fission GO:0016559 5 5 0,000 5,755E-03 0,04670539 ! histone demethylation GO:0016577 13 5 0,000 5,755E-03 0,04655074 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 5,755E-03 0,0463971 ! mitotic recombination GO:0006312 9 5 0,000 5,755E-03 0,04624448 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 5,755E-03 0,04609286 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,755E-03 0,04594223 ! metaphase plate congression GO:0051310 7 5 0,000 5,755E-03 0,04579258 ! regulation of sterol transport GO:0032371 7 5 0,000 5,755E-03 0,0456439 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 5,755E-03 0,04549619 ! enteric nervous system development GO:0048484 8 5 0,000 5,755E-03 0,04534943 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 5,755E-03 0,04520361 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 5,755E-03 0,04505873 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 5,755E-03 0,04491477 ! muscle cell proliferation GO:0033002 12 5 0,000 5,755E-03 0,04477173 ! skeletal muscle regeneration GO:0043403 8 5 0,000 5,755E-03 0,04462959 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 5,755E-03 0,04448836 ! B cell homeostasis GO:0001782 13 5 0,000 5,755E-03 0,04434802 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 5,755E-03 0,04420856 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 5,755E-03 0,04406998 ! metaphase GO:0051323 11 5 0,000 5,755E-03 0,04393226 ! melatonin biosynthetic process GO:0030187 7 5 0,000 5,755E-03 0,0437954 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 5,755E-03 0,04365939 ! cellular response to nutrient GO:0031670 8 5 0,000 5,755E-03 0,04352422 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 5,755E-03 0,04338988 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 5,755E-03 0,04325638 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 5,755E-03 0,04312369 ! regulation of hair follicle development GO:0051797 10 5 0,000 5,755E-03 0,04299181 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 5,755E-03 0,04286074 ! response to redox state GO:0051775 6 5 0,000 5,755E-03 0,04273046 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 5,755E-03 0,04260098 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 5,755E-03 0,04247227 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,755E-03 0,04234434 ! brown fat cell differentiation GO:0050873 7 5 0,000 5,755E-03 0,04221718 ! regulation of telomerase activity GO:0051972 7 5 0,000 5,755E-03 0,04209079 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,755E-03 0,04196514 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 5,755E-03 0,04184024 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,755E-03 0,04171609 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 5,755E-03 0,04159267 ! striatum development GO:0021756 14 5 0,000 5,755E-03 0,04146998 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 5,755E-03 0,04134801 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 5,755E-03 0,04122675 ! glial cell migration GO:0008347 10 5 0,000 5,755E-03 0,04110621 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,755E-03 0,04098636 ! neural plate morphogenesis GO:0001839 7 5 0,000 5,755E-03 0,04086722 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 5,755E-03 0,04074876 ! somatic stem cell maintenance GO:0035019 15 5 0,000 5,755E-03 0,04063099 ! T cell activation during immune response GO:0002286 9 5 0,000 5,755E-03 0,0405139 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 5,755E-03 0,04039748 ! negative regulation of lipase activity GO:0060192 8 5 0,000 5,755E-03 0,04028173 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 5,755E-03 0,04016663 ! neuroprotection GO:0043526 8 5 0,000 5,755E-03 0,0400522 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 5,755E-03 0,03993842 ! regulation of sensory perception GO:0051931 8 5 0,000 5,755E-03 0,03982528 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 5,755E-03 0,03971277 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 5,755E-03 0,03960091 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 5,755E-03 0,03948967 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 5,755E-03 0,03937905 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 5,755E-03 0,03926906 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 5,755E-03 0,03915967 ! sequestering of calcium ion GO:0051208 7 5 0,000 5,755E-03 0,0390509 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 5,755E-03 0,03894272 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 5,755E-03 0,03883514 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 5,755E-03 0,03872816 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 5,755E-03 0,03862176 ! spindle assembly GO:0051225 6 5 0,000 5,755E-03 0,03851595 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 5,755E-03 0,03841072 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 5,755E-03 0,03830606 ! protein palmitoylation GO:0018345 12 5 0,000 5,755E-03 0,03820196 ! drug metabolic process GO:0017144 7 5 0,000 5,755E-03 0,03809843 ! stem cell division GO:0017145 11 5 0,000 5,755E-03 0,03799547 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 5,755E-03 0,03789305 ! organ regeneration GO:0031100 7 5 0,000 5,755E-03 0,03779119 ! carnitine metabolic process GO:0009437 8 5 0,000 5,755E-03 0,03768987 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 5,755E-03 0,0375891 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 6,902E-03 0,04496133 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,902E-03 0,04484176 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 6,902E-03 0,04472281 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 6,902E-03 0,0446045 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 6,902E-03 0,04448681 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 6,902E-03 0,04436974 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 6,902E-03 0,04425328 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 6,902E-03 0,04413744 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 6,902E-03 0,04402219 ! response to oxygen radical GO:0000305 11 6 0,000 6,902E-03 0,04390755 ! positive regulation of axon extension GO:0045773 13 6 0,000 6,902E-03 0,04379351 ! myoblast cell fate commitment GO:0048625 18 6 0,000 6,902E-03 0,04368005 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 6,902E-03 0,04356718 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 6,902E-03 0,0434549 ! regulation of interferon-beta production GO:0032648 8 6 0,000 6,902E-03 0,04334319 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 6,902E-03 0,04323205 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 6,902E-03 0,04312148 ! forebrain regionalization GO:0021871 9 6 0,000 6,902E-03 0,04301148 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 6,902E-03 0,04290204 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 6,902E-03 0,04279315 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 6,902E-03 0,04268481 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 6,902E-03 0,04257702 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 6,902E-03 0,04246977 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 6,902E-03 0,04236307 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 6,902E-03 0,04225689 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 6,902E-03 0,04215125 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 6,902E-03 0,04204614 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 6,902E-03 0,04194154 ! malate metabolic process GO:0006108 13 6 0,000 6,902E-03 0,04183747 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 6,902E-03 0,04173391 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 6,902E-03 0,04163087 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 6,902E-03 0,04152833 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 6,902E-03 0,04142629 ! protein refolding GO:0042026 15 6 0,000 6,902E-03 0,04132476 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 6,902E-03 0,04122372 ! opsonization GO:0008228 8 6 0,000 6,902E-03 0,04112317 ! mating behavior GO:0007617 7 6 0,000 6,902E-03 0,04102312 ! erythrocyte maturation GO:0043249 8 6 0,000 6,902E-03 0,04092354 ! embryonic hemopoiesis GO:0035162 16 6 0,000 6,902E-03 0,04082446 ! protein amino acid dealkylation GO:0008214 15 6 0,000 6,902E-03 0,04072585 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 6,902E-03 0,04062771 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 6,902E-03 0,04053005 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 6,902E-03 0,04043285 ! response to interferon-gamma GO:0034341 16 6 0,000 6,902E-03 0,04033613 ! toxin metabolic process GO:0009404 11 6 0,000 6,902E-03 0,04023986 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 6,902E-03 0,04014405 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 6,902E-03 0,04004869 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 6,902E-03 0,03995379 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 6,902E-03 0,03985934 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 6,902E-03 0,03976533 ! cGMP-mediated signaling GO:0019934 14 6 0,000 6,902E-03 0,03967177 ! dorsal spinal cord development GO:0021516 10 6 0,000 6,902E-03 0,03957864 ! activation of MAPKKK activity GO:0000185 12 6 0,000 6,902E-03 0,03948595 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 6,902E-03 0,03939369 ! thymic T cell selection GO:0045061 16 6 0,000 6,902E-03 0,03930187 ! sphingoid catabolic process GO:0046521 8 6 0,000 6,902E-03 0,03921047 ! protein lipoylation GO:0009249 10 6 0,000 6,902E-03 0,03911949 ! transepithelial chloride transport GO:0030321 12 6 0,000 6,902E-03 0,03902894 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 6,902E-03 0,0389388 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 6,902E-03 0,03884908 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 6,902E-03 0,03875977 ! glutamate catabolic process GO:0006538 12 6 0,000 6,902E-03 0,03867087 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 6,902E-03 0,03858238 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 6,902E-03 0,03849429 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 6,902E-03 0,03840661 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 6,902E-03 0,03831932 ! hyperosmotic response GO:0006972 10 6 0,000 6,902E-03 0,03823243 ! L-serine biosynthetic process GO:0006564 7 6 0,000 6,902E-03 0,03814593 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 6,902E-03 0,03805982 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 6,902E-03 0,0379741 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 6,902E-03 0,03788876 ! urea metabolic process GO:0019627 7 6 0,000 6,902E-03 0,03780381 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 6,902E-03 0,03771924 ! neutrophil activation GO:0042119 7 6 0,000 6,902E-03 0,03763505 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 6,902E-03 0,03755123 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 6,902E-03 0,03746778 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 6,902E-03 0,0373847 ! paraxial mesoderm development GO:0048339 16 6 0,000 6,902E-03 0,03730199 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 6,902E-03 0,03721965 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 6,902E-03 0,03713767 ! neuron apoptosis GO:0051402 15 6 0,000 6,902E-03 0,03705604 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 6,902E-03 0,03697478 ! T cell mediated immunity GO:0002456 17 6 0,000 6,902E-03 0,03689387 ! negative regulation of platelet activation GO:0010544 9 6 0,000 6,902E-03 0,03681332 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 6,902E-03 0,03673312 ! carnitine transport GO:0015879 10 6 0,000 6,902E-03 0,03665326 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,902E-03 0,03657375 ! positive regulation of exocytosis GO:0045921 11 6 0,000 6,902E-03 0,03649459 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 6,902E-03 0,03641577 ! early endosome to late endosome transport GO:0045022 16 6 0,000 6,902E-03 0,03633729 ! 5S class rRNA transcription GO:0042791 13 6 0,000 6,902E-03 0,03625914 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 6,902E-03 0,03618133 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 6,902E-03 0,03610386 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 6,902E-03 0,03602671 ! sodium ion homeostasis GO:0055078 12 6 0,000 6,902E-03 0,03594989 ! establishment of spindle localization GO:0051293 16 6 0,000 6,902E-03 0,0358734 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 6,902E-03 0,03579724 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 6,902E-03 0,0357214 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 6,902E-03 0,03564588 ! response to UV-C GO:0010225 14 6 0,000 6,902E-03 0,03557068 ! astrocyte development GO:0014002 16 6 0,000 6,902E-03 0,03549579 ! protein targeting to lysosome GO:0006622 12 6 0,000 6,902E-03 0,03542122 ! purine base biosynthetic process GO:0009113 17 6 0,000 6,902E-03 0,03534696 ! interaction with symbiont GO:0051702 14 6 0,000 6,902E-03 0,03527301 ! regulation of dendrite development GO:0050773 16 6 0,000 6,902E-03 0,03519937 ! peptidyl-arginine modification GO:0018195 13 6 0,000 6,902E-03 0,03512604 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 6,902E-03 0,03505302 ! response to copper ion GO:0046688 10 6 0,000 6,902E-03 0,03498029 ! response to exogenous dsRNA GO:0043330 13 6 0,000 6,902E-03 0,03490787 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 6,902E-03 0,03483574 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,902E-03 0,03476392 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 6,902E-03 0,03469239 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 6,902E-03 0,03462115 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,902E-03 0,03455021 ! nucleoside catabolic process GO:0009164 10 6 0,000 6,902E-03 0,03447955 ! hair follicle maturation GO:0048820 8 6 0,000 6,902E-03 0,03440918 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 6,902E-03 0,0343391 ! Schwann cell development GO:0014044 15 6 0,000 6,902E-03 0,03426931 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 6,902E-03 0,0341998 ! response to pheromone GO:0019236 6 6 0,000 6,902E-03 0,03413057 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 6,902E-03 0,03406162 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 6,902E-03 0,03399294 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 6,902E-03 0,03392455 ! base conversion or substitution editing GO:0016553 6 6 0,000 6,902E-03 0,03385643 ! subpallium development GO:0021544 15 6 0,000 6,902E-03 0,03378858 ! neural tube patterning GO:0021532 8 6 0,000 6,902E-03 0,033721 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 6,902E-03 0,03365369 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 6,902E-03 0,03358665 ! maintenance of organ identity GO:0048496 9 6 0,000 6,902E-03 0,03351988 ! G2 phase GO:0051319 16 6 0,000 6,902E-03 0,03345337 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 6,902E-03 0,03338713 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 6,902E-03 0,03332115 ! oxygen homeostasis GO:0032364 10 6 0,000 6,902E-03 0,03325542 ! establishment of planar polarity GO:0001736 7 6 0,000 6,902E-03 0,03318996 ! regulation of mast cell activation GO:0033003 13 6 0,000 6,902E-03 0,03312476 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 6,902E-03 0,0330598 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 6,902E-03 0,03299511 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 6,902E-03 0,03293066 ! receptor internalization GO:0031623 11 6 0,000 6,902E-03 0,03286647 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 6,902E-03 0,03280253 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 6,902E-03 0,03273884 ! neutrophil homeostasis GO:0001780 11 6 0,000 6,902E-03 0,03267539 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,902E-03 0,03261219 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 6,902E-03 0,03254923 ! protein deubiquitination GO:0016579 16 6 0,000 6,902E-03 0,03248651 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 6,902E-03 0,03242404 ! protein destabilization GO:0031648 9 6 0,000 6,902E-03 0,0323618 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 6,902E-03 0,03229981 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 6,902E-03 0,03223805 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 6,902E-03 0,03217653 ! regulation of viral transcription GO:0046782 11 6 0,000 6,902E-03 0,03211524 ! progesterone metabolic process GO:0042448 12 6 0,000 6,902E-03 0,03205418 ! negative regulation of axon extension GO:0030517 24 6 0,000 6,902E-03 0,03199336 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 6,902E-03 0,03193277 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 6,902E-03 0,0318724 ! triglyceride catabolic process GO:0019433 10 6 0,000 6,902E-03 0,03181226 ! determination of adult lifespan GO:0008340 17 6 0,000 6,902E-03 0,03175235 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 6,902E-03 0,03169267 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 6,902E-03 0,03163321 ! neural plate development GO:0001840 9 6 0,000 6,902E-03 0,03157397 ! catecholamine transport GO:0051937 9 6 0,000 6,902E-03 0,03151495 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 6,902E-03 0,03145616 ! sensory cilium assembly GO:0035058 10 6 0,000 6,902E-03 0,03139758 ! organ or tissue specific immune response GO:0002251 8 6 0,000 6,902E-03 0,03133922 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 6,902E-03 0,03128108 ! maternal placenta development GO:0001893 12 6 0,000 6,902E-03 0,03122315 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 6,902E-03 0,03116544 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 6,902E-03 0,03110793 ! negative regulation of B cell activation GO:0050869 14 6 0,000 6,902E-03 0,03105065 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 6,902E-03 0,03099357 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 6,902E-03 0,0309367 ! positive regulation of coagulation GO:0050820 13 6 0,000 6,902E-03 0,03088004 ! cellular anion homeostasis GO:0030002 11 6 0,000 6,902E-03 0,03082358 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 8,047E-03 0,03587504 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 8,047E-03 0,0358097 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 8,047E-03 0,03574459 ! behavioral response to cocaine GO:0048148 14 7 0,000 8,047E-03 0,03567972 ! regulation of helicase activity GO:0051095 16 7 0,000 8,047E-03 0,03561508 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 8,047E-03 0,03555068 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 8,047E-03 0,03548651 ! sleep GO:0030431 16 7 0,000 8,047E-03 0,03542257 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 8,047E-03 0,03535886 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 8,047E-03 0,03529538 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 8,047E-03 0,03523212 ! prostate gland development GO:0030850 14 7 0,000 8,047E-03 0,0351691 ! nucleotide-sugar transport GO:0015780 11 7 0,000 8,047E-03 0,03510629 ! synaptonemal complex assembly GO:0007130 10 7 0,000 8,047E-03 0,03504372 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 8,047E-03 0,03498136 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 8,047E-03 0,03491923 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,047E-03 0,03485731 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 8,047E-03 0,03479562 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 8,047E-03 0,03473414 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 8,047E-03 0,03467288 ! SMAD protein complex assembly GO:0007183 13 7 0,000 8,047E-03 0,03461184 ! glycolipid transport GO:0046836 11 7 0,000 8,047E-03 0,03455101 ! protein amino acid sulfation GO:0006477 10 7 0,000 8,047E-03 0,03449039 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 8,047E-03 0,03442999 ! neuron adhesion GO:0007158 14 7 0,000 8,047E-03 0,0343698 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 8,047E-03 0,03430982 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 8,047E-03 0,03425004 ! establishment of tissue polarity GO:0007164 8 7 0,000 8,047E-03 0,03419048 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 8,047E-03 0,03413112 ! mRNA stabilization GO:0048255 18 7 0,000 8,047E-03 0,03407197 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 8,047E-03 0,03401302 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 8,047E-03 0,03395427 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 8,047E-03 0,03389573 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 8,047E-03 0,03383739 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 8,047E-03 0,03377925 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 8,047E-03 0,03372131 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 8,047E-03 0,03366357 ! lipoprotein transport GO:0042953 14 7 0,000 8,047E-03 0,03360602 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 8,047E-03 0,03354868 ! rhythmic behavior GO:0007622 17 7 0,000 8,047E-03 0,03349152 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 8,047E-03 0,03343457 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 8,047E-03 0,0333778 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 8,047E-03 0,03332123 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 8,047E-03 0,03326485 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 8,047E-03 0,03320866 ! regulation of odontogenesis GO:0042481 14 7 0,000 8,047E-03 0,03315266 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 8,047E-03 0,03309684 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 8,047E-03 0,03304122 ! mechanosensory behavior GO:0007638 16 7 0,000 8,047E-03 0,03298578 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 8,047E-03 0,03293053 ! positive regulation of isotype switching GO:0045830 17 7 0,000 8,047E-03 0,03287546 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 8,047E-03 0,03282058 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 8,047E-03 0,03276587 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,047E-03 0,03271136 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,047E-03 0,03265702 ! spinal cord patterning GO:0021511 14 7 0,000 8,047E-03 0,03260286 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 8,047E-03 0,03254888 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 8,047E-03 0,03249508 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 8,047E-03 0,03244146 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 8,047E-03 0,03238801 ! adrenal gland development GO:0030325 17 7 0,000 8,047E-03 0,03233474 ! cysteine metabolic process GO:0006534 13 7 0,000 8,047E-03 0,03228165 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 8,047E-03 0,03222873 ! ovulation GO:0030728 10 7 0,000 8,047E-03 0,03217598 ! adenohypophysis development GO:0021984 11 7 0,000 8,047E-03 0,03212341 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 8,047E-03 0,032071 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 8,047E-03 0,03201877 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 8,047E-03 0,03196671 ! microtubule nucleation GO:0007020 21 7 0,000 8,047E-03 0,03191481 ! proline biosynthetic process GO:0006561 10 7 0,000 8,047E-03 0,03186309 ! tryptophan metabolic process GO:0006568 11 7 0,000 8,047E-03 0,03181153 ! thyroid hormone generation GO:0006590 13 7 0,000 8,047E-03 0,03176014 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 8,047E-03 0,03170891 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 8,047E-03 0,03165785 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 8,047E-03 0,03160695 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 8,047E-03 0,03155622 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 8,047E-03 0,03150565 ! galactose metabolic process GO:0006012 13 7 0,000 8,047E-03 0,03145524 ! vesicle fusion GO:0006906 20 7 0,000 8,047E-03 0,03140499 ! response to dietary excess GO:0002021 8 7 0,000 8,047E-03 0,0313549 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 8,047E-03 0,03130498 ! intracellular pH reduction GO:0051452 13 7 0,000 8,047E-03 0,03125521 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 8,047E-03 0,03120559 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 8,047E-03 0,03115614 ! organ growth GO:0035265 15 7 0,000 8,047E-03 0,03110684 ! nucleoside transport GO:0015858 11 7 0,000 8,047E-03 0,0310577 ! nucleoside salvage GO:0043174 11 7 0,000 8,047E-03 0,03100871 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 8,047E-03 0,03095988 ! male sex determination GO:0030238 15 7 0,000 8,047E-03 0,0309112 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 8,047E-03 0,03086268 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 8,047E-03 0,0308143 ! parturition GO:0007567 16 7 0,000 8,047E-03 0,03076608 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 8,047E-03 0,03071801 ! rRNA modification GO:0000154 14 7 0,000 8,047E-03 0,03067008 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 8,047E-03 0,03062231 ! spindle checkpoint GO:0031577 16 7 0,000 8,047E-03 0,03057469 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 8,047E-03 0,03052721 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 8,047E-03 0,03047988 ! monocyte differentiation GO:0030224 16 7 0,000 8,047E-03 0,0304327 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 8,047E-03 0,03038566 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 8,047E-03 0,03033877 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 8,047E-03 0,03029203 ! hyaluronan metabolic process GO:0030212 9 7 0,000 8,047E-03 0,03024542 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 8,047E-03 0,03019896 ! anterograde axon cargo transport GO:0008089 18 7 0,000 8,047E-03 0,03015264 ! fibrinolysis GO:0042730 11 7 0,000 8,047E-03 0,03010647 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 8,047E-03 0,03006043 ! skeletal muscle contraction GO:0003009 8 7 0,000 8,047E-03 0,03001454 ! eating behavior GO:0042755 8 7 0,000 8,047E-03 0,02996879 ! B cell lineage commitment GO:0002326 21 7 0,000 8,047E-03 0,02992317 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 8,047E-03 0,0298777 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 8,047E-03 0,02983236 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 8,047E-03 0,02978716 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 8,047E-03 0,02974209 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 8,047E-03 0,02969717 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 8,047E-03 0,02965237 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 8,047E-03 0,02960772 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 8,047E-03 0,02956319 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 8,047E-03 0,02951881 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 8,047E-03 0,02947455 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 8,047E-03 0,02943043 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 8,047E-03 0,02938643 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 8,047E-03 0,02934257 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 8,047E-03 0,02929884 ! histone ubiquitination GO:0016574 9 7 0,000 8,047E-03 0,02925524 ! regulation of meiosis GO:0040020 12 7 0,000 8,047E-03 0,02921177 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 8,047E-03 0,02916843 ! T cell lineage commitment GO:0002360 16 7 0,000 8,047E-03 0,02912522 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 8,047E-03 0,02908214 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 8,047E-03 0,02903918 ! membrane to membrane docking GO:0022614 14 7 0,000 8,047E-03 0,02899635 ! transcription termination GO:0006353 14 7 0,000 8,047E-03 0,02895364 ! coenzyme A metabolic process GO:0015936 12 7 0,000 8,047E-03 0,02891107 ! anaphase GO:0051322 18 7 0,000 8,047E-03 0,02886861 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 8,047E-03 0,02882628 ! axonal fasciculation GO:0007413 19 7 0,000 8,047E-03 0,02878408 ! negative regulation of nuclear division GO:0051784 15 7 0,000 8,047E-03 0,02874199 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 8,047E-03 0,02870004 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 8,047E-03 0,0286582 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 8,047E-03 0,02861648 ! diuresis GO:0030146 12 7 0,000 8,047E-03 0,02857489 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 8,047E-03 0,02853342 ! thiamin metabolic process GO:0006772 7 7 0,000 8,047E-03 0,02849206 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 8,047E-03 0,02845083 ! antibiotic transport GO:0042891 9 7 0,000 8,047E-03 0,02840972 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 8,047E-03 0,02836872 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 8,047E-03 0,02832785 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 8,047E-03 0,02828709 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 8,047E-03 0,02824644 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 8,047E-03 0,02820592 ! melanin biosynthetic process GO:0042438 10 7 0,000 8,047E-03 0,02816551 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 8,047E-03 0,02812521 ! dopamine biosynthetic process GO:0042416 18 7 0,000 8,047E-03 0,02808503 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 8,047E-03 0,02804497 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 8,047E-03 0,02800502 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 8,047E-03 0,02796518 ! endosome to lysosome transport GO:0008333 12 7 0,000 8,047E-03 0,02792546 ! protein modification by small protein removal GO:0070646 19 7 0,000 8,047E-03 0,02788585 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 8,047E-03 0,02784635 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 8,047E-03 0,02780697 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 8,047E-03 0,02776769 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 8,047E-03 0,02772853 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,047E-03 0,02768947 ! muscle adaptation GO:0043500 13 7 0,000 8,047E-03 0,02765053 ! embryonic heart tube development GO:0035050 14 7 0,000 8,047E-03 0,02761169 ! retina homeostasis GO:0001895 12 7 0,000 8,047E-03 0,02757297 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 8,047E-03 0,02753435 ! protein amino acid prenylation GO:0018346 19 7 0,000 8,047E-03 0,02749584 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 8,047E-03 0,02745744 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 8,047E-03 0,02741914 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 9,192E-03 0,03127493 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 9,192E-03 0,03123143 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 9,192E-03 0,03118805 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 9,192E-03 0,0311448 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 9,192E-03 0,03110166 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 9,192E-03 0,03105864 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 9,192E-03 0,03101574 ! male meiosis GO:0007140 9 8 0,000 9,192E-03 0,03097296 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 9,192E-03 0,0309303 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 9,192E-03 0,03088776 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 9,192E-03 0,03084533 ! meiotic prophase I GO:0007128 14 8 0,000 9,192E-03 0,03080302 ! response to zinc ion GO:0010043 12 8 0,000 9,192E-03 0,03076082 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 9,192E-03 0,03071874 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 9,192E-03 0,03067677 ! oligopeptide transport GO:0006857 16 8 0,000 9,192E-03 0,03063492 ! actin-myosin filament sliding GO:0033275 13 8 0,000 9,192E-03 0,03059319 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 9,192E-03 0,03055156 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 9,192E-03 0,03051005 ! signal peptide processing GO:0006465 12 8 0,000 9,192E-03 0,03046865 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 9,192E-03 0,03042737 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 9,192E-03 0,03038619 ! macrophage chemotaxis GO:0048246 12 8 0,000 9,192E-03 0,03034513 ! succinate metabolic process GO:0006105 17 8 0,000 9,192E-03 0,03030418 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 9,192E-03 0,03026334 ! membrane hyperpolarization GO:0060081 11 8 0,000 9,192E-03 0,03022261 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 9,192E-03 0,03018199 ! estrogen metabolic process GO:0008210 17 8 0,000 9,192E-03 0,03014147 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 9,192E-03 0,03010107 ! T-helper 1 type immune response GO:0042088 12 8 0,000 9,192E-03 0,03006077 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 9,192E-03 0,03002059 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 9,192E-03 0,0299805 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 9,192E-03 0,02994053 ! reflex GO:0060004 17 8 0,000 9,192E-03 0,02990066 ! endothelial cell differentiation GO:0045446 17 8 0,000 9,192E-03 0,0298609 ! glycerolipid catabolic process GO:0046503 14 8 0,000 9,192E-03 0,02982125 ! hemoglobin metabolic process GO:0020027 14 8 0,000 9,192E-03 0,0297817 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 9,192E-03 0,02974225 ! pigment granule organization GO:0048753 17 8 0,000 9,192E-03 0,02970291 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 9,192E-03 0,02966367 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 9,192E-03 0,02962454 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 9,192E-03 0,0295855 ! astrocyte differentiation GO:0048708 19 8 0,000 9,192E-03 0,02954658 ! histidine catabolic process GO:0006548 10 8 0,000 9,192E-03 0,02950775 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 9,192E-03 0,02946903 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 9,192E-03 0,0294304 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 9,192E-03 0,02939188 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 9,192E-03 0,02935346 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 9,192E-03 0,02931514 ! regulation of pigmentation during development GO:0048070 25 8 0,000 9,192E-03 0,02927692 ! melanin metabolic process GO:0006582 17 8 0,000 9,192E-03 0,0292388 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 9,192E-03 0,02920078 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 9,192E-03 0,02916285 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 9,192E-03 0,02912503 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 9,192E-03 0,0290873 ! macrophage activation GO:0042116 13 8 0,000 9,192E-03 0,02904967 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 9,192E-03 0,02901214 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 9,192E-03 0,02897471 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 9,192E-03 0,02893737 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 9,192E-03 0,02890013 ! purine salvage GO:0043101 12 8 0,000 9,192E-03 0,02886298 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 9,192E-03 0,02882593 ! regulation of vascular permeability GO:0043114 12 8 0,000 9,192E-03 0,02878897 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 9,192E-03 0,02875211 ! osteoblast development GO:0002076 17 8 0,000 9,192E-03 0,02871534 ! positive regulation of vasodilation GO:0045909 14 8 0,000 9,192E-03 0,02867867 ! negative regulation of translational initiation GO:0045947 12 8 0,000 9,192E-03 0,02864209 ! Schwann cell differentiation GO:0014037 21 8 0,000 9,192E-03 0,0286056 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 9,192E-03 0,02856921 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 9,192E-03 0,02853291 ! response to UV-B GO:0010224 17 8 0,000 9,192E-03 0,0284967 ! protein targeting to vacuole GO:0006623 14 8 0,000 9,192E-03 0,02846058 ! protein retention in ER lumen GO:0006621 14 8 0,000 9,192E-03 0,02842455 ! intermediate filament organization GO:0045109 12 8 0,000 9,192E-03 0,02838862 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 9,192E-03 0,02835278 ! cellular extravasation GO:0045123 13 8 0,000 9,192E-03 0,02831702 ! cardiac muscle cell development GO:0055013 14 8 0,000 9,192E-03 0,02828136 ! response to antibiotic GO:0046677 11 8 0,000 9,192E-03 0,02824578 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 9,192E-03 0,0282103 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 9,192E-03 0,0281749 ! DNA topological change GO:0006265 12 8 0,000 9,192E-03 0,0281396 ! response to tropane GO:0014073 15 8 0,000 9,192E-03 0,02810438 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 9,192E-03 0,02806925 ! melanosome transport GO:0032402 13 8 0,000 9,192E-03 0,0280342 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 9,192E-03 0,02799925 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 9,192E-03 0,02796438 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 9,192E-03 0,0279296 ! mast cell activation GO:0045576 14 8 0,000 9,192E-03 0,0278949 ! multicellular organismal aging GO:0010259 20 8 0,000 9,192E-03 0,0278603 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 9,192E-03 0,02782577 ! gas homeostasis GO:0033483 14 8 0,000 9,192E-03 0,02779133 ! dendrite morphogenesis GO:0048813 14 8 0,000 9,192E-03 0,02775698 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 9,192E-03 0,02772271 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 9,192E-03 0,02768853 ! nucleosome disassembly GO:0006337 14 8 0,000 9,192E-03 0,02765443 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 9,192E-03 0,02762042 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 9,192E-03 0,02758648 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 9,192E-03 0,02755264 ! establishment of chromosome localization GO:0051303 14 8 0,000 9,192E-03 0,02751887 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 9,192E-03 0,02748519 ! intracellular lipid transport GO:0032365 16 8 0,000 9,192E-03 0,02745159 ! response to tumor cell GO:0002347 16 8 0,000 9,192E-03 0,02741807 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 9,192E-03 0,02738463 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 9,192E-03 0,02735128 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 9,192E-03 0,027318 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 9,192E-03 0,02728481 ! positive regulation of epidermis development GO:0045684 13 8 0,000 9,192E-03 0,0272517 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 9,192E-03 0,02721866 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 9,192E-03 0,02718571 ! hormone catabolic process GO:0042447 17 8 0,000 9,192E-03 0,02715284 ! glycolipid catabolic process GO:0019377 16 8 0,000 9,192E-03 0,02712005 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 9,192E-03 0,02708733 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 9,192E-03 0,0270547 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 9,192E-03 0,02702214 ! positive regulation of glucose import GO:0046326 8 8 0,000 9,192E-03 0,02698966 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 9,192E-03 0,02695726 ! adult feeding behavior GO:0008343 10 8 0,000 9,192E-03 0,02692494 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 9,192E-03 0,02689269 ! ATP catabolic process GO:0006200 11 8 0,000 9,192E-03 0,02686052 ! blastocyst growth GO:0001832 19 8 0,000 9,192E-03 0,02682843 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 9,192E-03 0,02679642 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 9,192E-03 0,02676448 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 9,192E-03 0,02673262 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 9,192E-03 0,02670083 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 9,192E-03 0,02666912 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 9,192E-03 0,02663748 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 9,192E-03 0,02660592 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 9,192E-03 0,02657444 ! amino sugar catabolic process GO:0046348 11 8 0,000 9,192E-03 0,02654302 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 9,192E-03 0,02651169 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 9,192E-03 0,02648042 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 9,192E-03 0,02644923 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 9,192E-03 0,02641812 ! behavioral response to nicotine GO:0035095 12 8 0,000 9,192E-03 0,02638707 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 9,192E-03 0,0263561 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 9,192E-03 0,0263252 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 9,192E-03 0,02629438 ! NAD biosynthetic process GO:0009435 17 8 0,000 9,192E-03 0,02626362 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 9,192E-03 0,02623294 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 9,192E-03 0,02620233 ! axon extension GO:0048675 16 9 0,000 0,01033489 0,02942672 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01033489 0,02939246 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01033489 0,02935828 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01033489 0,02932419 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01033489 0,02929017 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01033489 0,02925623 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01033489 0,02922237 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01033489 0,02918858 ! reproductive behavior GO:0019098 22 9 0,000 0,01033489 0,02915488 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01033489 0,02912125 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01033489 0,0290877 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01033489 0,02905423 ! UTP metabolic process GO:0046051 10 9 0,000 0,01033489 0,02902083 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01033489 0,02898751 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01033489 0,02895427 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01033489 0,0289211 ! artery development GO:0060840 25 9 0,000 0,01033489 0,02888801 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01033489 0,028855 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01033489 0,02882206 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01033489 0,0287892 ! equilibrioception GO:0050957 20 9 0,000 0,01033489 0,02875641 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01033489 0,02872369 ! chemosensory behavior GO:0007635 21 9 0,000 0,01033489 0,02869105 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01033489 0,02865848 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01033489 0,02862599 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01033489 0,02859357 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01033489 0,02856123 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01033489 0,02852895 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01033489 0,02849675 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01033489 0,02846463 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01033489 0,02843257 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01033489 0,02840059 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01033489 0,02836868 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01033489 0,02833684 ! protein targeting to ER GO:0045047 25 9 0,000 0,01033489 0,02830507 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01033489 0,02827338 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01033489 0,02824175 ! T cell selection GO:0045058 27 9 0,000 0,01033489 0,0282102 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01033489 0,02817871 ! glycine catabolic process GO:0006546 15 9 0,000 0,01033489 0,0281473 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01033489 0,02811595 ! endosome organization GO:0007032 20 9 0,000 0,01033489 0,02808468 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01033489 0,02805347 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01033489 0,02802234 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01033489 0,02799127 ! mannose metabolic process GO:0006013 13 9 0,000 0,01033489 0,02796027 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01033489 0,02792934 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01033489 0,02789848 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01033489 0,02786769 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01033489 0,02783696 ! receptor clustering GO:0043113 20 9 0,000 0,01033489 0,0278063 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01033489 0,02777571 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01033489 0,02774519 ! retinol metabolic process GO:0042572 20 9 0,000 0,01033489 0,02771474 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01033489 0,02768435 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01033489 0,02765402 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01033489 0,02762377 ! macrophage differentiation GO:0030225 15 9 0,000 0,01033489 0,02759358 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01033489 0,02756345 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01033489 0,0275334 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01033489 0,0275034 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01033489 0,02747348 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01033489 0,02744361 ! response to amine stimulus GO:0014075 13 9 0,000 0,01033489 0,02741382 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01033489 0,02738408 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01033489 0,02735441 ! erythrocyte development GO:0048821 17 9 0,000 0,01033489 0,02732481 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01033489 0,02729527 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01033489 0,02726579 ! renal water homeostasis GO:0003091 15 9 0,000 0,01033489 0,02723638 ! postreplication repair GO:0006301 25 9 0,000 0,01033489 0,02720703 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01033489 0,02717774 ! icosanoid secretion GO:0032309 15 9 0,000 0,01033489 0,02714852 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01033489 0,02711936 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01033489 0,02709026 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01033489 0,02706123 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01033489 0,02703225 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01033489 0,02700334 ! sterol catabolic process GO:0016127 14 9 0,000 0,01033489 0,02697449 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01033489 0,0269457 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01033489 0,02691698 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01033489 0,02688831 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01033489 0,02685971 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01033489 0,02683116 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01033489 0,02680268 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01033489 0,02677426 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01033489 0,02674589 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01033489 0,02671759 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01033489 0,02668935 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01033489 0,02666117 ! purine base metabolic process GO:0006144 25 9 0,000 0,01033489 0,02663304 ! pigment granule transport GO:0051904 17 9 0,000 0,01033489 0,02660498 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01033489 0,02657697 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01033489 0,02654903 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01033489 0,02652114 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01033489 0,02649331 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01033489 0,02646554 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01033489 0,02643783 ! mitochondrion localization GO:0051646 18 9 0,000 0,01033489 0,02641017 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01147675 0,0292975 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01147675 0,02926692 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01147675 0,0292364 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01147675 0,02920595 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01147675 0,02917555 ! associative learning GO:0008306 21 10 0,000 0,01147675 0,02914523 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01147675 0,02911496 ! phosphate transport GO:0006817 24 10 0,000 0,01147675 0,02908476 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01147675 0,02905462 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01147675 0,02902454 ! CTP metabolic process GO:0046036 11 10 0,000 0,01147675 0,02899453 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01147675 0,02896457 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01147675 0,02893468 ! GTP metabolic process GO:0046039 11 10 0,000 0,01147675 0,02890485 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01147675 0,02887508 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01147675 0,02884538 ! social behavior GO:0035176 29 10 0,000 0,01147675 0,02881573 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01147675 0,02878615 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01147675 0,02875662 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01147675 0,02872716 ! androgen metabolic process GO:0008209 17 10 0,000 0,01147675 0,02869776 ! phospholipid efflux GO:0033700 19 10 0,000 0,01147675 0,02866841 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01147675 0,02863913 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01147675 0,02860991 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01147675 0,02858074 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01147675 0,02855164 ! lung alveolus development GO:0048286 26 10 0,000 0,01147675 0,02852259 ! pathogenesis GO:0009405 17 10 0,000 0,01147675 0,02849361 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01147675 0,02846468 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01147675 0,02843581 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01147675 0,028407 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01147675 0,02837825 ! endoderm development GO:0007492 18 10 0,000 0,01147675 0,02834955 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01147675 0,02832092 ! arginine catabolic process GO:0006527 17 10 0,000 0,01147675 0,02829234 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01147675 0,02826382 ! proline metabolic process GO:0006560 13 10 0,000 0,01147675 0,02823535 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01147675 0,02820695 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01147675 0,0281786 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01147675 0,02815031 ! V(D)J recombination GO:0033151 34 10 0,000 0,01147675 0,02812207 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01147675 0,0280939 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01147675 0,02806577 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01147675 0,02803771 ! B cell proliferation GO:0042100 19 10 0,000 0,01147675 0,0280097 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01147675 0,02798174 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01147675 0,02795385 ! multicellular organism growth GO:0035264 19 10 0,000 0,01147675 0,027926 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01147675 0,02789822 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01147675 0,02787048 ! ruffle organization GO:0031529 17 10 0,000 0,01147675 0,02784281 ! epithelial cell development GO:0002064 21 10 0,000 0,01147675 0,02781519 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01147675 0,02778762 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01147675 0,02776011 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01147675 0,02773265 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01147675 0,02770524 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01147675 0,02767789 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01147675 0,0276506 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01147675 0,02762336 ! motor axon guidance GO:0008045 22 10 0,000 0,01147675 0,02759617 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01147675 0,02756903 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01147675 0,02754195 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01147675 0,02751492 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01147675 0,02748795 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01147675 0,02746103 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01147675 0,02743416 ! segment specification GO:0007379 15 10 0,000 0,01147675 0,02740734 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01147675 0,02738057 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01147675 0,02735386 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01147675 0,0273272 ! response to dsRNA GO:0043331 23 10 0,000 0,01147675 0,02730059 ! DNA ligation GO:0006266 18 10 0,000 0,01147675 0,02727403 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01147675 0,02724753 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01147675 0,02722108 ! melanosome localization GO:0032400 16 10 0,000 0,01147675 0,02719467 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01147675 0,02716832 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01147675 0,02714202 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01147675 0,02711577 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01147675 0,02708957 ! induction of an organ GO:0001759 17 10 0,000 0,01147675 0,02706342 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01147675 0,02703733 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01147675 0,02701128 ! protein sumoylation GO:0016925 17 10 0,000 0,01147675 0,02698528 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01147675 0,02695933 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01147675 0,02693344 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01147675 0,02690759 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01147675 0,02688179 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01147675 0,02685604 ! salivary gland development GO:0007431 28 10 0,000 0,01147675 0,02683034 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01147675 0,02680469 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01147675 0,02677909 ! midbrain development GO:0030901 14 10 0,000 0,01147675 0,02675354 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01147675 0,02672803 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01147675 0,02670258 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01147675 0,02667717 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01147675 0,02665181 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01147675 0,0266265 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01147675 0,02660124 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01147675 0,02657603 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01147675 0,02655086 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01147675 0,02652574 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01147675 0,02650067 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01147675 0,02647564 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01147675 0,02645067 ! blastocyst formation GO:0001825 18 10 0,000 0,01147675 0,02642574 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01147675 0,02640085 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01147675 0,02637602 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01147675 0,02635123 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01147675 0,02632649 ! response to nicotine GO:0035094 20 10 0,000 0,01147675 0,02630179 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01147675 0,02627714 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01147675 0,02625254 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01261734 0,02883457 ! respiratory burst GO:0045730 17 11 0,000 0,01261734 0,02880762 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01261734 0,02878072 ! neuron fate specification GO:0048665 18 11 0,000 0,01261734 0,02875387 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01261734 0,02872707 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01261734 0,02870033 ! thyroid gland development GO:0030878 26 11 0,000 0,01261734 0,02867363 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01261734 0,02864698 ! synapsis GO:0007129 14 11 0,000 0,01261734 0,02862038 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01261734 0,02859383 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01261734 0,02856733 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01261734 0,02854088 ! response to pain GO:0048265 27 11 0,000 0,01261734 0,02851448 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01261734 0,02848812 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01261734 0,02846182 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01261734 0,02843556 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01261734 0,02840935 ! bone resorption GO:0045453 16 11 0,000 0,01261734 0,0283832 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01261734 0,02835708 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01261734 0,02833102 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01261734 0,028305 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01261734 0,02827904 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01261734 0,02825312 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01261734 0,02822724 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01261734 0,02820142 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01261734 0,02817564 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01261734 0,02814991 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01261734 0,02812422 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01261734 0,02809859 ! UV protection GO:0009650 20 11 0,000 0,01261734 0,028073 ! adult heart development GO:0007512 16 11 0,000 0,01261734 0,02804745 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01261734 0,02802195 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01261734 0,0279965 ! macroautophagy GO:0016236 19 11 0,000 0,01261734 0,0279711 ! temperature homeostasis GO:0001659 18 11 0,000 0,01261734 0,02794574 ! behavioral fear response GO:0001662 27 11 0,000 0,01261734 0,02792043 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01261734 0,02789516 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01261734 0,02786994 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01261734 0,02784476 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01261734 0,02781963 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01261734 0,02779454 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01261734 0,0277695 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01261734 0,02774451 ! regulation of organ growth GO:0046620 14 11 0,000 0,01261734 0,02771956 ! pigment granule localization GO:0051875 20 11 0,000 0,01261734 0,02769465 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01261734 0,02766979 ! vasoconstriction GO:0042310 20 11 0,000 0,01261734 0,02764498 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01261734 0,02762021 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01261734 0,02759548 ! embryonic axis specification GO:0000578 19 11 0,000 0,01261734 0,0275708 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01261734 0,02754616 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01261734 0,02752156 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01261734 0,02749701 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01261734 0,0274725 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01261734 0,02744804 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01261734 0,02742362 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01261734 0,02739924 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01261734 0,02737491 ! prophase GO:0051324 17 11 0,000 0,01261734 0,02735062 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01261734 0,02732637 ! nucleosome positioning GO:0016584 15 11 0,000 0,01261734 0,02730217 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01261734 0,02727801 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01261734 0,02725389 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01261734 0,02722981 ! apical protein localization GO:0045176 18 11 0,000 0,01261734 0,02720578 ! acid secretion GO:0046717 20 11 0,000 0,01261734 0,02718179 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01261734 0,02715784 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01261734 0,02713393 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01261734 0,02711007 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01261734 0,02708625 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01261734 0,02706247 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01261734 0,02703873 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01261734 0,02701503 ! cholesterol efflux GO:0033344 21 11 0,000 0,01261734 0,02699137 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01261734 0,02696776 ! oocyte development GO:0048599 20 11 0,000 0,01261734 0,02694419 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01261734 0,02692066 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01261734 0,02689716 ! embryonic gut development GO:0048566 19 11 0,000 0,01261734 0,02687371 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01261734 0,0268503 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01261734 0,02682694 ! activation of innate immune response GO:0002218 16 11 0,000 0,01261734 0,02680361 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01261734 0,02678032 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01261734 0,02675707 ! lysogeny GO:0030069 22 11 0,000 0,01261734 0,02673387 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01261734 0,0267107 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01261734 0,02668758 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01261734 0,02666449 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01261734 0,02664144 ! nucleus localization GO:0051647 22 11 0,000 0,01261734 0,02661844 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01375663 0,02899694 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01375663 0,02897194 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01375663 0,02894699 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01375663 0,02892208 ! virus-host interaction GO:0019048 30 12 0,000 0,01375663 0,02889721 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01375663 0,02887238 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01375663 0,0288476 ! protein complex disassembly GO:0043241 28 12 0,000 0,01375663 0,02882286 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01375663 0,02879816 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01375663 0,02877351 ! hippocampus development GO:0021766 29 12 0,000 0,01375663 0,02874889 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01375663 0,02872432 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01375663 0,02869979 ! T cell proliferation GO:0042098 32 12 0,000 0,01375663 0,0286753 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01375663 0,02865086 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01375663 0,02862645 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01375663 0,02860209 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01375663 0,02857777 ! drug transport GO:0015893 16 12 0,000 0,01375663 0,02855349 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01375663 0,02852925 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01375663 0,02850505 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01375663 0,02848089 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01375663 0,02845678 ! focal adhesion formation GO:0048041 37 12 0,000 0,01375663 0,0284327 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01375663 0,02840867 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01375663 0,02838468 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01375663 0,02836072 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01375663 0,02833681 ! lipid digestion GO:0044241 21 12 0,000 0,01375663 0,02831294 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01375663 0,0282891 ! entry into host cell GO:0030260 34 12 0,000 0,01375663 0,02826531 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01375663 0,02824156 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01375663 0,02821785 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01375663 0,02819417 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01375663 0,02817054 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01375663 0,02814695 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01375663 0,02812339 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01375663 0,02809988 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01375663 0,0280764 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01375663 0,02805297 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01375663 0,02802957 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01375663 0,02800621 ! cranial nerve development GO:0021545 23 12 0,000 0,01375663 0,02798289 ! fucose catabolic process GO:0019317 25 12 0,000 0,01375663 0,02795961 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01375663 0,02793637 ! histone acetylation GO:0016573 27 12 0,000 0,01375663 0,02791317 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01375663 0,02789 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01375663 0,02786688 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01375663 0,02784379 ! zymogen activation GO:0031638 18 12 0,000 0,01375663 0,02782074 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01375663 0,02779773 ! T cell homeostasis GO:0043029 28 12 0,000 0,01375663 0,02777476 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01375663 0,02775182 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01375663 0,02772892 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01375663 0,02770606 ! oocyte differentiation GO:0009994 21 12 0,000 0,01375663 0,02768324 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01375663 0,02766046 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01375663 0,02763771 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01375663 0,027615 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01375663 0,02759233 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01375663 0,02756969 ! defense response to fungus GO:0050832 15 12 0,000 0,01375663 0,0275471 ! developmental induction GO:0031128 22 12 0,000 0,01375663 0,02752453 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01375663 0,02750201 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01375663 0,02747952 ! response to cold GO:0009409 17 12 0,000 0,01375663 0,02745707 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01375663 0,02743466 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01375663 0,02741228 ! localization within membrane GO:0051668 26 12 0,000 0,01375663 0,02738994 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01489465 0,02963162 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01489465 0,02960751 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01489465 0,02958344 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01489465 0,02955941 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01489465 0,02953541 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01489465 0,02951146 ! peroxisomal transport GO:0043574 28 13 0,000 0,01489465 0,02948754 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01489465 0,02946367 ! cartilage condensation GO:0001502 22 13 0,000 0,01489465 0,02943983 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01489465 0,02941603 ! organelle fusion GO:0048284 36 13 0,000 0,01489465 0,02939227 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01489465 0,02936855 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01489465 0,02934486 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01489465 0,02932122 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01489465 0,02929761 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01489465 0,02927404 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01489465 0,02925051 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01489465 0,02922701 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01489465 0,02920355 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01489465 0,02918014 ! methionine metabolic process GO:0006555 31 13 0,000 0,01489465 0,02915675 ! plasma membrane organization GO:0007009 27 13 0,000 0,01489465 0,02913341 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01489465 0,0291101 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01489465 0,02908683 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01489465 0,0290636 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01489465 0,02904041 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01489465 0,02901725 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01489465 0,02899413 ! exocrine system development GO:0035272 34 13 0,000 0,01489465 0,02897104 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01489465 0,02894799 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01489465 0,02892498 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01489465 0,02890201 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01489465 0,02887907 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01489465 0,02885617 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01489465 0,0288333 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01489465 0,02881047 ! protein homotetramerization GO:0051289 24 13 0,000 0,01489465 0,02878768 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01489465 0,02876492 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01489465 0,0287422 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01489465 0,02871952 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01489465 0,02869687 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01489465 0,02867425 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01489465 0,02865168 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01489465 0,02862913 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01489465 0,02860663 ! histone methylation GO:0016571 29 13 0,000 0,01489465 0,02858415 ! chromatin silencing GO:0006342 29 13 0,000 0,01489465 0,02856172 ! gland morphogenesis GO:0022612 31 13 0,000 0,01489465 0,02853932 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01489465 0,02851695 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01489465 0,02849462 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01489465 0,02847232 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01489465 0,02845006 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01489465 0,02842783 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01489465 0,02840564 ! spleen development GO:0048536 24 13 0,000 0,01489465 0,02838349 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01489465 0,02836136 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01489465 0,02833927 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01489465 0,02831722 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01489465 0,0282952 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01489465 0,02827322 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01489465 0,02825126 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01489465 0,02822935 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01489465 0,02820746 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01489465 0,02818561 ! insulin secretion GO:0030073 24 13 0,000 0,01489465 0,0281638 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01489465 0,02814202 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01489465 0,02812027 ! acrosome reaction GO:0007340 19 13 0,000 0,01489465 0,02809855 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01489465 0,02807687 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01489465 0,02805523 ! rRNA transcription GO:0009303 28 14 0,000 0,01603138 0,03017309 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01603138 0,03014986 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01603138 0,03012667 ! water transport GO:0006833 21 14 0,000 0,01603138 0,03010351 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01603138 0,03008039 ! non-recombinational repair GO:0000726 29 14 0,000 0,01603138 0,03005731 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01603138 0,03003426 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01603138 0,03001124 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01603138 0,02998826 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01603138 0,02996532 ! lipid localization GO:0010876 32 14 0,000 0,01603138 0,02994241 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01603138 0,02991954 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01603138 0,0298967 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01603138 0,02987389 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01603138 0,02985112 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01603138 0,02982839 ! arginine metabolic process GO:0006525 21 14 0,000 0,01603138 0,02980569 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01603138 0,02978302 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01603138 0,02976039 ! regulation of heart rate GO:0002027 25 14 0,000 0,01603138 0,02973779 ! fear response GO:0042596 34 14 0,000 0,01603138 0,02971523 ! organic alcohol transport GO:0015850 29 14 0,000 0,01603138 0,0296927 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01603138 0,02967021 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01603138 0,02964775 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01603138 0,02962532 ! bone mineralization GO:0030282 18 14 0,000 0,01603138 0,02960293 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01603138 0,02958057 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01603138 0,02955824 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01603138 0,02953595 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01603138 0,02951369 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01603138 0,02949147 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01603138 0,02946928 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01603138 0,02944712 ! ribosome assembly GO:0042255 18 14 0,000 0,01603138 0,029425 ! cerebellum development GO:0021549 23 14 0,000 0,01603138 0,02940291 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01603138 0,02938085 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01603138 0,02935882 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01603138 0,02933683 ! response to gamma radiation GO:0010332 30 14 0,000 0,01603138 0,02931487 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01603138 0,02929295 ! NADP metabolic process GO:0006739 24 14 0,000 0,01603138 0,02927105 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01603138 0,02924919 ! oxygen transport GO:0015671 22 14 0,000 0,01603138 0,02922737 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01603138 0,02920557 ! male genitalia development GO:0030539 26 14 0,000 0,01603138 0,02918381 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01603138 0,02916208 ! regulation of axon extension GO:0030516 43 14 0,000 0,01603138 0,02914038 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01603138 0,02911871 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01603138 0,02909708 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01716684 0,03113481 ! lactation GO:0007595 30 15 0,000 0,01716684 0,03111171 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01716684 0,03108865 ! reproductive cellular process GO:0048610 22 15 0,000 0,01716684 0,03106562 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01716684 0,03104263 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01716684 0,03101967 ! superoxide anion generation GO:0042554 22 15 0,000 0,01716684 0,03099674 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01716684 0,03097385 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01716684 0,03095099 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01716684 0,03092816 ! copper ion transport GO:0006825 22 15 0,000 0,01716684 0,03090537 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01716684 0,03088261 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01716684 0,03085989 ! sulfate transport GO:0008272 27 15 0,000 0,01716684 0,0308372 ! response to cAMP GO:0051591 25 15 0,000 0,01716684 0,03081454 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01716684 0,03079191 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01716684 0,03076932 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01716684 0,03074677 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01716684 0,03072424 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01716684 0,03070175 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01716684 0,03067929 ! vesicle coating GO:0006901 38 15 0,000 0,01716684 0,03065686 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01716684 0,03063447 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01716684 0,03061211 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01716684 0,03058978 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01716684 0,03056748 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01716684 0,03054522 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01716684 0,03052299 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01716684 0,03050079 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01716684 0,03047862 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01716684 0,03045649 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01716684 0,03043439 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01716684 0,03041232 ! histone deacetylation GO:0016575 24 15 0,000 0,01716684 0,03039028 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01716684 0,03036828 ! water homeostasis GO:0030104 28 15 0,000 0,01716684 0,0303463 ! cofactor transport GO:0051181 30 15 0,000 0,01716684 0,03032436 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01716684 0,03030245 ! muscle maintenance GO:0046716 26 15 0,000 0,01716684 0,03028057 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01716684 0,03025872 ! intestinal absorption GO:0050892 31 15 0,000 0,01716684 0,03023691 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01716684 0,03021512 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01716684 0,03019337 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01716684 0,03017165 ! cell killing GO:0001906 32 15 0,000 0,01716684 0,03014996 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01716684 0,0301283 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01716684 0,03010667 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01716684 0,03008507 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01716684 0,0300635 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01716684 0,03004197 ! actin filament polymerization GO:0030041 27 15 0,000 0,01716684 0,03002046 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01716684 0,02999899 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,01830102 0,0319581 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01830102 0,03193527 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01830102 0,03191248 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01830102 0,03188972 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01830102 0,03186699 ! bone remodeling GO:0046849 28 16 0,000 0,01830102 0,03184429 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01830102 0,03182162 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01830102 0,03179899 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01830102 0,03177639 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01830102 0,03175382 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01830102 0,03173129 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01830102 0,03170878 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01830102 0,03168631 ! startle response GO:0001964 28 16 0,000 0,01830102 0,03166387 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01830102 0,03164146 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01830102 0,03161908 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01830102 0,03159674 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01830102 0,03157442 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01830102 0,03155214 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01830102 0,03152989 ! pituitary gland development GO:0021983 30 16 0,000 0,01830102 0,03150767 ! response to osmotic stress GO:0006970 27 16 0,000 0,01830102 0,03148548 ! lysosomal transport GO:0007041 31 16 0,000 0,01830102 0,03146332 ! L-amino acid transport GO:0015807 33 16 0,000 0,01830102 0,0314412 ! stem cell development GO:0048864 46 16 0,000 0,01830102 0,0314191 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01830102 0,03139704 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01830102 0,031375 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01830102 0,031353 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01830102 0,03133103 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01830102 0,03130909 ! axon cargo transport GO:0008088 46 16 0,000 0,01830102 0,03128718 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01830102 0,0312653 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01830102 0,03124345 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01830102 0,03122163 ! DNA replication initiation GO:0006270 28 16 0,000 0,01830102 0,03119985 ! neuron recognition GO:0008038 40 16 0,000 0,01830102 0,03117809 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01830102 0,03115636 ! tissue regeneration GO:0042246 27 16 0,000 0,01830102 0,03113467 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01830102 0,031113 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01830102 0,03109136 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01830102 0,03106976 ! biomineral formation GO:0031214 22 16 0,000 0,01830102 0,03104818 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01830102 0,03102664 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01830102 0,03100512 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01830102 0,03098363 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01830102 0,03096218 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01830102 0,03094075 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01830102 0,03091935 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01830102 0,03089798 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01830102 0,03087664 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,01830102 0,03085534 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,01943392 0,0327428 ! metencephalon development GO:0022037 32 17 0,000 0,01943392 0,03272023 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,01943392 0,0326977 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,01943392 0,03267519 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,01943392 0,03265272 ! signal complex assembly GO:0007172 47 17 0,000 0,01943392 0,03263028 ! filopodium assembly GO:0046847 42 17 0,000 0,01943392 0,03260787 ! endothelial cell migration GO:0043542 31 17 0,000 0,01943392 0,03258549 ! gene silencing by RNA GO:0031047 38 17 0,000 0,01943392 0,03256314 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,01943392 0,03254082 ! glial cell development GO:0021782 28 17 0,000 0,01943392 0,03251853 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,01943392 0,03249627 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,01943392 0,03247405 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,01943392 0,03245185 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,01943392 0,03242968 ! myoblast differentiation GO:0045445 50 17 0,000 0,01943392 0,03240755 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,01943392 0,03238544 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,01943392 0,03236336 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,01943392 0,03234132 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,01943392 0,0323193 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,01943392 0,03229732 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,01943392 0,03227536 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,01943392 0,03225343 ! NAD metabolic process GO:0019674 33 17 0,000 0,01943392 0,03223154 ! membrane budding GO:0006900 42 17 0,000 0,01943392 0,03220967 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,01943392 0,03218783 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,01943392 0,03216603 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,01943392 0,03214425 ! genitalia development GO:0048806 32 17 0,000 0,01943392 0,0321225 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,01943392 0,03210078 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,01943392 0,03207909 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,01943392 0,03205743 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,01943392 0,0320358 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,01943392 0,0320142 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,01943392 0,03199262 ! steroid catabolic process GO:0006706 34 17 0,000 0,01943392 0,03197108 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,01943392 0,03194957 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,01943392 0,03192808 ! gas transport GO:0015669 26 17 0,000 0,01943392 0,03190662 ! organic cation transport GO:0015695 32 17 0,000 0,01943392 0,03188519 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,01943392 0,0318638 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,01943392 0,03184242 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,01943392 0,03182108 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02056554 0,03365145 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02056554 0,03362892 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02056554 0,03360643 ! limbic system development GO:0021761 40 18 0,000 0,02056554 0,03358397 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02056554 0,03356153 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02056554 0,03353913 ! adult walking behavior GO:0007628 36 18 0,000 0,02056554 0,03351675 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02056554 0,03349441 ! heart looping GO:0001947 34 18 0,000 0,02056554 0,03347209 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02056554 0,03344981 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02056554 0,03342755 ! centrosome cycle GO:0007098 26 18 0,000 0,02056554 0,03340533 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02056554 0,03338313 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02056554 0,03336096 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02056554 0,03333883 ! glycine metabolic process GO:0006544 30 18 0,000 0,02056554 0,03331672 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02056554 0,03329464 ! response to retinoic acid GO:0032526 31 18 0,000 0,02056554 0,03327259 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02056554 0,03325057 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,02056554 0,03322858 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02056554 0,03320662 ! DNA integration GO:0015074 32 18 0,000 0,02056554 0,03318468 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02056554 0,03316278 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02056554 0,03314091 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02056554 0,03311906 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02056554 0,03309724 ! neural crest cell migration GO:0001755 41 18 0,000 0,02056554 0,03307545 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02056554 0,03305369 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02056554 0,03303196 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02056554 0,03301026 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02056554 0,03298858 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02056554 0,03296694 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02056554 0,03294532 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02056554 0,03292373 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02056554 0,03290217 ! detection of bacterium GO:0016045 22 18 0,000 0,02056554 0,03288064 ! nerve development GO:0021675 34 18 0,000 0,02056554 0,03285913 ! defense response to virus GO:0051607 43 18 0,000 0,02056554 0,03283766 ! microspike assembly GO:0030035 46 18 0,000 0,02056554 0,03281621 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02056554 0,03279479 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02169589 0,03457473 ! positive regulation of translation GO:0045727 31 19 0,000 0,02169589 0,03455219 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02169589 0,03452968 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02169589 0,0345072 ! neuron maturation GO:0042551 46 19 0,000 0,02169589 0,03448475 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02169589 0,03446233 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02169589 0,03443993 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02169589 0,03441757 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02169589 0,03439524 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02169589 0,03437293 ! inositol metabolic process GO:0006020 33 19 0,000 0,02169589 0,03435065 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02169589 0,03432841 ! memory GO:0007613 34 19 0,000 0,02169589 0,03430619 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02169589 0,034284 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02169589 0,03426183 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02169589 0,0342397 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02169589 0,0342176 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02169589 0,03419552 ! cerebral cortex development GO:0021987 40 19 0,000 0,02169589 0,03417347 ! pigmentation during development GO:0048066 42 19 0,000 0,02169589 0,03415145 ! response to vitamin A GO:0033189 32 19 0,000 0,02169589 0,03412946 ! heme metabolic process GO:0042168 40 19 0,000 0,02169589 0,0341075 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02169589 0,03408557 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02169589 0,03406366 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02169589 0,03404178 ! response to fungus GO:0009620 26 19 0,000 0,02169589 0,03401993 ! peptide cross-linking GO:0018149 39 19 0,000 0,02169589 0,03399811 ! protein export from nucleus GO:0006611 40 19 0,000 0,02169589 0,03397632 ! heart process GO:0003015 32 19 0,000 0,02169589 0,03395455 GO:0060047|heart contraction, ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02169589 0,03393282 ! visual learning GO:0008542 38 19 0,000 0,02169589 0,03391111 ! cellular pigmentation GO:0033059 37 19 0,000 0,02169589 0,03388942 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02169589 0,03386777 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02169589 0,03384614 ! vitamin transport GO:0051180 31 19 0,000 0,02169589 0,03382454 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02169589 0,03380297 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02169589 0,03378143 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02169589 0,03375991 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02169589 0,03373842 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02169589 0,03371696 ! cilium assembly GO:0042384 38 19 0,000 0,02169589 0,03369552 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02169589 0,03367412 ! protein secretion GO:0009306 45 20 0,000 0,02282497 0,03540406 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02282497 0,03538159 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02282497 0,03535916 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02282497 0,03533675 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02282497 0,03531437 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,02282497 0,03529202 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02282497 0,0352697 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02282497 0,0352474 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02282497 0,03522514 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,02282497 0,0352029 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02282497 0,03518069 ! response to vitamin GO:0033273 36 20 0,000 0,02282497 0,03515851 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02282497 0,03513635 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,02282497 0,03511423 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02282497 0,03509213 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02282497 0,03507006 ! response to alkaloid GO:0043279 38 20 0,000 0,02282497 0,03504802 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02282497 0,035026 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02282497 0,03500401 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02282497 0,03498205 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02282497 0,03496012 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,02282497 0,03493822 ! actin filament bundle formation GO:0051017 47 20 0,000 0,02282497 0,03491634 ! body fluid secretion GO:0007589 33 20 0,000 0,02282497 0,03489449 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02282497 0,03487267 ! peptide secretion GO:0002790 38 20 0,000 0,02282497 0,03485087 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02282497 0,0348291 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,02282497 0,03480736 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02282497 0,03478565 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02282497 0,03476396 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02282497 0,0347423 ! cell-cell junction organization GO:0045216 43 20 0,000 0,02282497 0,03472067 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02282497 0,03469906 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02282497 0,03467748 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02282497 0,03465593 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02282497 0,03463441 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02282497 0,03461291 ! regulation of glucose import GO:0046324 30 20 0,000 0,02282497 0,03459144 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02282497 0,03456999 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02282497 0,03454857 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02282497 0,03452718 ! negative regulation of translation GO:0017148 32 20 0,000 0,02282497 0,03450581 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02282497 0,03448447 ! regulation of cell killing GO:0031341 46 21 0,000 0,02395277 0,03616602 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02395277 0,03614368 ! hormone secretion GO:0046879 39 21 0,000 0,02395277 0,03612137 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02395277 0,03609909 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02395277 0,03607683 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02395277 0,0360546 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,02395277 0,0360324 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02395277 0,03601023 ! ovarian follicle development GO:0001541 39 21 0,000 0,02395277 0,03598808 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02395277 0,03596596 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02395277 0,03594387 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02395277 0,03592181 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02395277 0,03589977 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02395277 0,03587776 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02395277 0,03585577 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02395277 0,03583382 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02395277 0,03581189 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02395277 0,03578998 ! sensory perception of pain GO:0019233 33 21 0,000 0,02395277 0,03576811 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02395277 0,03574626 ! diencephalon development GO:0021536 36 21 0,000 0,02395277 0,03572443 ! collagen fibril organization GO:0030199 62 21 0,000 0,02395277 0,03570264 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02395277 0,03568087 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02395277 0,03565912 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02395277 0,03563741 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02395277 0,03561572 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02395277 0,03559405 ! collagen catabolic process GO:0030574 29 21 0,000 0,02395277 0,03557242 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02395277 0,0355508 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02395277 0,03552922 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02395277 0,03550766 ! actin filament-based movement GO:0030048 47 21 0,000 0,02395277 0,03548613 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02395277 0,03546462 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02507931 0,03711009 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02507931 0,03708762 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02507931 0,03706518 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02507931 0,03704278 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,02507931 0,03702039 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02507931 0,03699804 ! microtubule-based transport GO:0010970 59 22 0,000 0,02507931 0,03697571 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02507931 0,03695341 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02507931 0,03693113 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,02507931 0,03690889 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,02507931 0,03688666 ! cellular response to starvation GO:0009267 37 22 0,000 0,02507931 0,03686447 ! vacuolar transport GO:0007034 41 22 0,000 0,02507931 0,0368423 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02507931 0,03682016 ! fucose metabolic process GO:0006004 44 22 0,000 0,02507931 0,03679805 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,02507931 0,03677596 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02507931 0,0367539 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,02507931 0,03673186 ! ureteric bud development GO:0001657 50 22 0,000 0,02507931 0,03670986 ! cell aging GO:0007569 48 22 0,000 0,02507931 0,03668787 ! stem cell differentiation GO:0048863 57 22 0,000 0,02507931 0,03666592 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02507931 0,03664399 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02507931 0,03662209 ! cytolysis GO:0019835 27 22 0,000 0,02507931 0,03660021 ! renal system process GO:0003014 42 22 0,000 0,02507931 0,03657836 ! vasodilation GO:0042311 40 22 0,000 0,02507931 0,03655653 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02507931 0,03653473 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02507931 0,03651296 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,02507931 0,03649122 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02507931 0,03646949 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02507931 0,0364478 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,02507931 0,03642613 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,02507931 0,03640449 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,02507931 0,03638287 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02507931 0,03636128 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02507931 0,03633971 ! sarcomere organization GO:0045214 32 22 0,000 0,02507931 0,03631817 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02507931 0,03629665 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02507931 0,03627516 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02507931 0,0362537 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02507931 0,03623226 ! gut development GO:0048565 44 22 0,000 0,02507931 0,03621085 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02507931 0,03618946 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,02507931 0,03616809 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02507931 0,03614676 ! protein stabilization GO:0050821 41 22 0,000 0,02507931 0,03612544 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,02620458 0,03772409 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,02620458 0,03770187 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,02620458 0,03767968 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,02620458 0,03765752 ! gluconeogenesis GO:0006094 38 23 0,000 0,02620458 0,03763538 ! glycerol metabolic process GO:0006071 40 23 0,000 0,02620458 0,03761327 ! viral genome replication GO:0019079 44 23 0,000 0,02620458 0,03759118 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,02620458 0,03756912 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,02620458 0,03754708 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,02620458 0,03752508 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,02620458 0,03750309 ! regeneration GO:0031099 42 23 0,000 0,02620458 0,03748114 ! axis specification GO:0009798 43 23 0,000 0,02620458 0,0374592 ! visual behavior GO:0007632 46 23 0,000 0,02620458 0,0374373 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,02620458 0,03741542 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,02620458 0,03739356 ! response to ethanol GO:0045471 47 23 0,000 0,02620458 0,03737173 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,02620458 0,03734993 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,02620458 0,03732815 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,02620458 0,0373064 ! peroxisome organization GO:0007031 43 23 0,000 0,02620458 0,03728467 ! lysosome organization GO:0007040 47 23 0,000 0,02620458 0,03726297 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,02620458 0,03724129 ! vesicle targeting GO:0006903 49 23 0,000 0,02620458 0,03721964 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,02620458 0,03719801 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,02620458 0,03717641 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,02620458 0,03715483 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,02620458 0,03713328 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,02620458 0,03711176 ! DNA modification GO:0006304 36 23 0,000 0,02620458 0,03709025 ! fatty acid transport GO:0015908 47 23 0,000 0,02620458 0,03706878 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,02620458 0,03704733 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,02620458 0,0370259 ! hormone transport GO:0009914 41 23 0,000 0,02620458 0,0370045 ! cell-cell recognition GO:0009988 28 23 0,000 0,02620458 0,03698312 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,02620458 0,03696177 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,02620458 0,03694044 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,02620458 0,03691913 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,02732858 0,03848053 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,02732858 0,03845836 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,02732858 0,03843622 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,02732858 0,0384141 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,02732858 0,03839201 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,02732858 0,03836995 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,02732858 0,03834791 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,02732858 0,0383259 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,02732858 0,03830391 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,02732858 0,03828194 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,02732858 0,03826001 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,02732858 0,03823809 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,02732858 0,03821621 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,02732858 0,03819434 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,02732858 0,0381725 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,02732858 0,03815069 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,02732858 0,0381289 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,02732858 0,03810714 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,02732858 0,0380854 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,02732858 0,03806369 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,02732858 0,038042 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,02732858 0,03802034 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,02732858 0,0379987 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,02732858 0,03797708 ! membrane depolarization GO:0051899 45 24 0,000 0,02732858 0,03795549 ! pallium development GO:0021543 56 24 0,000 0,02732858 0,03793393 ! oogenesis GO:0048477 44 24 0,000 0,02732858 0,03791239 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,02732858 0,03789087 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,02732858 0,03786938 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,02732858 0,03784791 ! platelet activation GO:0030168 41 24 0,000 0,02732858 0,03782647 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,02732858 0,03780505 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,02732858 0,03778365 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,02732858 0,03776228 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,02732858 0,03774093 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,02732858 0,03771961 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,02732858 0,03769831 ! regulation of amine transport GO:0051952 41 24 0,000 0,02732858 0,03767704 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02845131 0,03920279 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02845131 0,03918069 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02845131 0,03915862 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02845131 0,03913657 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02845131 0,03911455 ! phototransduction GO:0007602 37 25 0,000 0,02845131 0,03909255 ! keratinization GO:0031424 37 25 0,000 0,02845131 0,03907057 ! vasculogenesis GO:0001570 49 25 0,000 0,02845131 0,03904862 ! vacuole organization GO:0007033 49 25 0,000 0,02845131 0,0390267 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02845131 0,0390048 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02845131 0,03898292 ! receptor metabolic process GO:0043112 53 25 0,000 0,02845131 0,03896107 ! chromosome condensation GO:0030261 48 25 0,000 0,02845131 0,03893924 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02845131 0,03891744 ! regulation of behavior GO:0050795 48 25 0,000 0,02845131 0,03889566 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02845131 0,03887391 ! interaction with host GO:0051701 66 25 0,000 0,02845131 0,03885218 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02845131 0,03883048 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02845131 0,03880879 ! immunoglobulin production GO:0002377 62 25 0,000 0,02845131 0,03878714 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02845131 0,03876551 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,02845131 0,0387439 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02845131 0,03872231 ! liver development GO:0001889 55 25 0,000 0,02845131 0,03870075 ! protein tetramerization GO:0051262 57 25 0,000 0,02845131 0,03867922 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,02957278 0,04018148 ! myelination GO:0042552 50 26 0,000 0,02957278 0,04015915 ! initiation of viral infection GO:0019059 60 26 0,000 0,02957278 0,04013683 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,02957278 0,04011455 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,02957278 0,04009229 ! molting cycle process GO:0022404 52 26 0,000 0,02957278 0,04007005 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,02957278 0,04004784 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,02957278 0,04002565 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,02957278 0,04000349 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,02957278 0,03998135 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,02957278 0,03995924 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,02957278 0,03993715 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,02957278 0,03991508 ! digestive system process GO:0022600 49 26 0,000 0,02957278 0,03989304 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,02957278 0,03987103 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,02957278 0,03984904 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,02957278 0,03982707 ! osteoblast differentiation GO:0001649 63 26 0,000 0,02957278 0,03980513 ! neural crest cell development GO:0014032 59 26 0,000 0,02957278 0,03978321 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,02957278 0,03976131 ! negative regulation of cell development GO:0010721 83 26 0,000 0,02957278 0,03973944 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,02957278 0,03971759 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,02957278 0,03969577 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,02957278 0,03967397 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,02957278 0,0396522 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,02957278 0,03963045 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,02957278 0,03960872 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,02957278 0,03958702 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,02957278 0,03956534 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,02957278 0,03954368 ! blastocyst development GO:0001824 50 26 0,000 0,02957278 0,03952205 ! telomere organization GO:0032200 46 26 0,000 0,02957278 0,03950044 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,02957278 0,03947885 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,02957278 0,03945729 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,02957278 0,03943575 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03069299 0,04090724 ! embryonic pattern specification GO:0009880 49 27 0,000 0,03069299 0,04088493 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,03069299 0,04086265 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,03069299 0,0408404 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,03069299 0,04081816 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,03069299 0,04079596 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,03069299 0,04077377 ! iron ion transport GO:0006826 65 27 0,000 0,03069299 0,04075161 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,03069299 0,04072948 ! superoxide metabolic process GO:0006801 41 27 0,000 0,03069299 0,04070737 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,03069299 0,04068528 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,03069299 0,04066322 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,03069299 0,04064118 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,03069299 0,04061916 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,03069299 0,04059717 ! response to starvation GO:0042594 47 27 0,000 0,03069299 0,0405752 ! response to toxin GO:0009636 49 27 0,000 0,03069299 0,04055326 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,03069299 0,04053133 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,03069299 0,04050944 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,03069299 0,04048756 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,03069299 0,04046571 ! leukocyte proliferation GO:0070661 59 27 0,000 0,03069299 0,04044389 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,03069299 0,04042209 ! neuron fate commitment GO:0048663 52 28 0,000 0,03181193 0,04187314 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,03181193 0,04185059 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,03181193 0,04182807 ! protein amino acid acylation GO:0043543 59 28 0,000 0,03181193 0,04180557 ! vesicle docking GO:0048278 55 28 0,000 0,03181193 0,04178309 ! circadian rhythm GO:0007623 56 28 0,000 0,03181193 0,04176064 ! dendrite development GO:0016358 67 28 0,000 0,03181193 0,04173821 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,03181193 0,04171581 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03181193 0,04169343 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03181193 0,04167107 ! base-excision repair GO:0006284 41 28 0,000 0,03181193 0,04164874 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03181193 0,04162643 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03181193 0,04160415 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03181193 0,04158189 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03181193 0,04155965 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,03181193 0,04153744 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03181193 0,04151525 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03181193 0,04149309 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03181193 0,04147095 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03181193 0,04144883 ! lipid oxidation GO:0034440 48 28 0,000 0,03181193 0,04142673 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,03181193 0,04140466 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03181193 0,04138262 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,03292962 0,04281376 ! translational initiation GO:0006413 66 29 0,000 0,03292962 0,04279099 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03292962 0,04276824 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03292962 0,04274551 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03292962 0,04272281 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,03292962 0,04270014 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03292962 0,04267748 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03292962 0,04265486 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03292962 0,04263225 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03292962 0,04260967 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,03292962 0,04258711 ! somitogenesis GO:0001756 52 29 0,000 0,03292962 0,04256458 ! synaptogenesis GO:0007416 46 29 0,000 0,03292962 0,04254207 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,03292962 0,04251959 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03292962 0,04249713 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03292962 0,04247469 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,03292962 0,04245227 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,03404604 0,0438684 ! phenol metabolic process GO:0018958 56 30 0,000 0,03404604 0,04384528 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03404604 0,04382217 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03404604 0,0437991 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03404604 0,04377605 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03404604 0,04375302 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03404604 0,04373001 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03404604 0,04370704 ! acute-phase response GO:0006953 50 30 0,000 0,03404604 0,04368408 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03404604 0,04366115 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03404604 0,04363824 ! myofibril assembly GO:0030239 50 30 0,000 0,03404604 0,04361536 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,03404604 0,0435925 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03404604 0,04356966 ! cell fate determination GO:0001709 64 30 0,000 0,03404604 0,04354685 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03404604 0,04352406 ! phospholipid transport GO:0015914 65 30 0,000 0,03404604 0,0435013 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03404604 0,04347856 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03404604 0,04345585 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,03404604 0,04343315 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03404604 0,04341048 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03404604 0,04338784 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,03404604 0,04336522 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,03516121 0,0447623 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,03516121 0,04473898 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,03516121 0,04471569 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,03516121 0,04469243 ! cell junction assembly GO:0034329 85 31 0,000 0,03516121 0,04466919 ! regulation of innate immune response GO:0045088 57 31 0,000 0,03516121 0,04464597 ! ovulation cycle process GO:0022602 55 31 0,000 0,03516121 0,04462278 ! peptide transport GO:0015833 60 31 0,000 0,03516121 0,04459961 ! male gonad development GO:0008584 56 31 0,000 0,03516121 0,04457646 ! iron ion homeostasis GO:0055072 60 31 0,000 0,03516121 0,04455334 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,03516121 0,04453025 ! detection of light stimulus GO:0009583 44 31 0,000 0,03516121 0,04450717 ! natural killer cell activation GO:0030101 50 31 0,000 0,03516121 0,04448413 ! ensheathment of neurons GO:0007272 64 31 0,000 0,03516121 0,0444611 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,03516121 0,0444381 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,03516121 0,04441512 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,03516121 0,04439217 ! eye morphogenesis GO:0048592 65 31 0,000 0,03516121 0,04436924 ! response to heat GO:0009408 54 31 0,000 0,03516121 0,04434633 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,03516121 0,04432345 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,03627513 0,04570404 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,03627513 0,04568048 ! collagen metabolic process GO:0032963 49 32 0,000 0,03627513 0,04565695 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,03627513 0,04563344 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,03627513 0,04560995 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,03627513 0,04558649 ! metanephros development GO:0001656 81 32 0,000 0,03627513 0,04556305 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,03627513 0,04553964 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,03627513 0,04551625 ! muscle cell development GO:0055001 52 32 0,000 0,03627513 0,04549288 ! mesoderm formation GO:0001707 73 32 0,000 0,03627513 0,04546954 ! ovulation cycle GO:0042698 57 32 0,000 0,03627513 0,04544622 ! peripheral nervous system development GO:0007422 68 32 0,000 0,03627513 0,04542293 ! BMP signaling pathway GO:0030509 71 32 0,000 0,03627513 0,04539966 ! hindbrain development GO:0030902 65 32 0,000 0,03627513 0,04537641 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,03627513 0,04535319 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,03627513 0,04532999 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,03627513 0,04530682 ! gene silencing GO:0016458 71 32 0,000 0,03627513 0,04528367 ! regulation of pH GO:0006885 56 33 0,000 0,03738779 0,0466488 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,03738779 0,04662499 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,03738779 0,0466012 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,03738779 0,04657744 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,03738779 0,0465537 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,03738779 0,04652998 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,03738779 0,04650629 ! response to ionizing radiation GO:0010212 74 33 0,000 0,03738779 0,04648263 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,03738779 0,04645898 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,03738779 0,04643536 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,03738779 0,04641177 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,03738779 0,0463882 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,03738779 0,04636465 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,03738779 0,04634113 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,03738779 0,04631763 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,03849919 0,04767031 ! glial cell differentiation GO:0010001 67 34 0,000 0,03849919 0,04764616 ! post-embryonic development GO:0009791 76 34 0,000 0,03849919 0,04762204 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,03849919 0,04759794 ! cholesterol transport GO:0030301 62 34 0,000 0,03849919 0,04757386 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,03849919 0,04754981 ! spliceosome assembly GO:0000245 75 34 0,000 0,03849919 0,04752578 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,03849919 0,04750178 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,03849919 0,0474778 ! formation of primary germ layer GO:0001704 76 34 0,000 0,03849919 0,04745385 ! cell fate specification GO:0001708 56 34 0,000 0,03849919 0,04742991 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,03849919 0,04740601 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,03849919 0,04738213 ! adult locomotory behavior GO:0008344 62 34 0,000 0,03849919 0,04735827 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,03849919 0,04733443 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,03960934 0,04867486 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,03960934 0,04865039 ! negative regulation of secretion GO:0051048 68 35 0,000 0,03960934 0,04862594 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,03960934 0,04860152 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,03960934 0,04857712 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,03960934 0,04855275 ! membrane docking GO:0022406 69 35 0,000 0,03960934 0,0485284 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,03960934 0,04850407 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,03960934 0,04847977 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,03960934 0,0484555 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,03960934 0,04843124 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,03960934 0,04840702 ! ceramide metabolic process GO:0006672 72 35 0,000 0,03960934 0,04838281 ! telencephalon development GO:0021537 81 35 0,000 0,03960934 0,04835863 ! sterol transport GO:0015918 63 35 0,000 0,03960934 0,04833448 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,03960934 0,04831035 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,03960934 0,04828624 ! placenta development GO:0001890 53 35 0,000 0,03960934 0,04826216 ! vesicle localization GO:0051648 70 35 0,000 0,03960934 0,0482381 ! regulation of muscle development GO:0048634 82 36 0,000 0,04071825 0,04956386 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,04071825 0,04953918 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,04071825 0,04951452 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,04071825 0,04948989 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,04071825 0,04946528 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,04071825 0,04944069 ! positive regulation of cell development GO:0010720 85 36 0,000 0,04071825 0,04941613 ! protein targeting to membrane GO:0006612 75 36 0,000 0,04071825 0,0493916 ! regulation of proteolysis GO:0030162 77 36 0,000 0,04071825 0,04936708 ! aerobic respiration GO:0009060 56 36 0,000 0,04071825 0,0493426 ! cytokine production GO:0001816 68 36 0,000 0,04071825 0,04931813 ! embryonic organ development GO:0048568 67 36 0,000 0,04071825 0,04929369 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,04071825 0,04926928 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,0418259 0,05058449 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,0418259 0,05055946 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,0418259 0,05053446 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,0418259 0,05050948 ! sister chromatid segregation GO:0000819 65 37 0,000 0,0418259 0,05048452 ! odontogenesis GO:0042476 74 37 0,000 0,0418259 0,05045959 ! actomyosin structure organization GO:0031032 68 37 0,000 0,0418259 0,05043468 ! cell junction organization GO:0034330 96 37 0,000 0,0418259 0,0504098 ! tissue remodeling GO:0048771 78 37 0,000 0,0418259 0,05038495 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,0418259 0,05036011 ! female gonad development GO:0008585 71 37 0,000 0,0418259 0,05033531 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,0418259 0,05031052 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,0418259 0,05028576 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,0418259 0,05026103 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,0429323 0,0515652 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,0429323 0,05153986 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,0429323 0,05151455 ! organic anion transport GO:0015711 82 38 0,000 0,0429323 0,05148926 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,0429323 0,05146399 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,0429323 0,05143875 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,0429323 0,05141354 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,0429323 0,05138835 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,0429323 0,05136318 ! regulation of protein stability GO:0031647 77 38 0,000 0,0429323 0,05133804 ! spermatid development GO:0007286 69 38 0,000 0,0429323 0,05131293 ! glycogen metabolic process GO:0005977 63 38 0,000 0,0429323 0,05128783 ! pigment metabolic process GO:0042440 87 38 0,000 0,0429323 0,05126277 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,0429323 0,05123772 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,04403746 0,05253102 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,04403746 0,05250538 ! negative regulation of binding GO:0051100 71 39 0,000 0,04403746 0,05247977 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,04403746 0,05245418 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,04403746 0,05242862 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,04403746 0,05240308 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,04403746 0,05237757 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,04403746 0,05235208 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,04403746 0,05232662 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,04403746 0,05230118 ! glucan metabolic process GO:0044042 64 39 0,000 0,04403746 0,05227576 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,04514138 0,05356017 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,04514138 0,05353417 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,04514138 0,05350819 ! learning GO:0007612 82 40 0,000 0,04514138 0,05348224 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,04514138 0,05345632 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,04514138 0,05343042 ! lipid homeostasis GO:0055088 75 40 0,000 0,04514138 0,05340454 ! mismatch repair GO:0006298 58 40 0,000 0,04514138 0,0533787 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,04514138 0,05335287 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,04514138 0,05332707 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,04514138 0,0533013 ! RNA export from nucleus GO:0006405 61 41 0,000 0,04624405 0,05457691 ! mRNA catabolic process GO:0006402 79 41 0,000 0,04624405 0,05455056 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,04624405 0,05452423 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,04624405 0,05449793 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,04624405 0,05447165 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,04624405 0,0544454 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,04624405 0,05441918 ! gliogenesis GO:0042063 91 41 0,000 0,04624405 0,05439297 ! feeding behavior GO:0007631 69 41 0,000 0,04624405 0,0543668 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,04624405 0,05434065 ! mesenchymal cell development GO:0014031 94 41 0,000 0,04624405 0,05431452 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,04624405 0,05428842 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,04624405 0,05426235 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,04624405 0,0542363 ! spermatid differentiation GO:0048515 73 41 0,000 0,04624405 0,05421027 ! RNA modification GO:0009451 64 41 0,000 0,04624405 0,05418427 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,04734548 0,05544822 ! ear morphogenesis GO:0042471 64 42 0,000 0,04734548 0,05542166 ! organic ether metabolic process GO:0018904 59 42 0,000 0,04734548 0,05539511 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,04734548 0,0553686 ! T cell differentiation GO:0030217 93 42 0,000 0,04734548 0,0553421 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,04734548 0,05531564 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,04734548 0,0552892 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,04734548 0,05526278 ! regulation of protein secretion GO:0050708 77 42 0,000 0,04734548 0,05523639 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,04734548 0,05521002 ! cytokinesis GO:0000910 84 42 0,000 0,04734548 0,05518368 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,04734548 0,05515737 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,04844566 0,05641218 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,04844566 0,0563853 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,04844566 0,05635845 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,04844566 0,05633163 ! regulation of tube size GO:0035150 76 43 0,000 0,04844566 0,05630483 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,04844566 0,05627806 ! glucose transport GO:0015758 66 43 0,000 0,04844566 0,05625131 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,04844566 0,05622459 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,04844566 0,05619789 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,04844566 0,05617122 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,04844566 0,05614457 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,04844566 0,05611795 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,04844566 0,05609135 ! segmentation GO:0035282 78 43 0,000 0,04844566 0,05606478 ! ion transmembrane transport GO:0034220 79 43 0,000 0,04844566 0,05603824 ! neuron migration GO:0001764 85 43 0,000 0,04844566 0,05601171 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,04844566 0,05598522 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,04954461 0,05722812 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,04954461 0,05720108 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,04954461 0,05717406 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,04954461 0,05714706 ! hexose transport GO:0008645 68 44 0,000 0,04954461 0,05712009 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,04954461 0,05709315 ! striated muscle contraction GO:0006941 85 44 0,000 0,04954461 0,05706623 ! phagocytosis GO:0006909 105 44 0,000 0,04954461 0,05703934 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,04954461 0,05701247 ! double-strand break repair GO:0006302 85 44 0,000 0,04954461 0,05698563 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,05064232 0,05822079 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,05064232 0,05819341 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,05064232 0,05816605 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,05064232 0,05813871 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,05064232 0,05811141 ! B cell differentiation GO:0030183 124 45 0,000 0,05064232 0,05808412 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,05064232 0,05805687 ! female gamete generation GO:0007292 71 45 0,000 0,05064232 0,05802964 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,05064232 0,05800243 ! developmental growth GO:0048589 88 45 0,000 0,05064232 0,05797525 ! maintenance of location in cell GO:0051651 101 45 0,000 0,05064232 0,0579481 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,05173879 0,05917503 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,05173879 0,05914734 ! glycolysis GO:0006096 71 46 0,000 0,05173879 0,05911968 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,05173879 0,05909204 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,05173879 0,05906442 ! leukocyte migration GO:0050900 75 46 0,000 0,05173879 0,05903684 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,05173879 0,05900927 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,05173879 0,05898174 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,05173879 0,05895423 ! pigmentation GO:0043473 103 46 0,000 0,05173879 0,05892674 ! cell growth GO:0016049 90 46 0,000 0,05173879 0,05889928 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,05173879 0,05887185 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,05283403 0,0600901 ! response to insulin stimulus GO:0032868 98 47 0,000 0,05283403 0,06006214 ! positive regulation of defense response GO:0031349 88 48 0,000 0,05392803 0,06127729 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,05392803 0,0612488 ! mitochondrial transport GO:0006839 94 48 0,000 0,05392803 0,06122034 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,05392803 0,06119191 ! cellular component disassembly GO:0022411 89 48 0,000 0,05392803 0,0611635 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,05392803 0,06113512 ! endosome transport GO:0016197 127 48 0,000 0,05392803 0,06110676 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,05392803 0,06107843 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,05392803 0,06105013 ! male sex differentiation GO:0046661 93 48 0,000 0,05392803 0,06102185 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,05392803 0,0609936 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,05392803 0,06096538 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,05392803 0,06093718 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,05392803 0,060909 ! methylation GO:0032259 97 48 0,000 0,05392803 0,06088086 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,0550208 0,06208583 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,0550208 0,06205716 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,0550208 0,06202852 ! JNK cascade GO:0007254 106 49 0,000 0,0550208 0,06199991 ! protein homooligomerization GO:0051260 84 49 0,000 0,0550208 0,06197133 ! regulation of action potential GO:0001508 102 50 0,000 0,05611234 0,06317163 ! regulation of ion transport GO:0043269 86 50 0,000 0,05611234 0,06314253 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,05611234 0,06311346 ! endocrine system development GO:0035270 109 50 0,000 0,05611234 0,06308442 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,05611234 0,0630554 ! regulation of ossification GO:0030278 123 50 0,000 0,05611234 0,06302641 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,05611234 0,06299745 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,05611234 0,06296851 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,05611234 0,0629396 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,05611234 0,06291071 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,05720265 0,0641037 ! viral infectious cycle GO:0019058 104 51 0,000 0,05720265 0,06407431 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,05720265 0,06404494 ! peptide metabolic process GO:0006518 80 51 0,000 0,05720265 0,0640156 ! response to temperature stimulus GO:0009266 84 51 0,000 0,05720265 0,06398629 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,05720265 0,06395701 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,05720265 0,06392775 ! positive regulation of binding GO:0051099 88 52 0,000 0,05829172 0,06511508 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,05829172 0,06508532 ! Notch signaling pathway GO:0007219 111 52 0,000 0,05829172 0,06505559 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,05829172 0,06502588 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,05829172 0,0649962 ! excretion GO:0007588 87 52 0,000 0,05829172 0,06496655 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,05829172 0,06493693 ! histone modification GO:0016570 104 52 0,000 0,05829172 0,06490733 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,05829172 0,06487776 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,05829172 0,06484822 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,05829172 0,0648187 ! amino acid activation GO:0043038 98 52 0,000 0,05829172 0,06478921 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,05937958 0,06596831 ! inner ear development GO:0048839 89 53 0,000 0,05937958 0,06593832 ! chromatin remodeling GO:0006338 122 53 0,000 0,05937958 0,06590836 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,05937958 0,06587843 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,05937958 0,06584853 ! vesicle organization GO:0016050 127 53 0,000 0,05937958 0,06581865 ! cartilage development GO:0051216 99 53 0,000 0,05937958 0,0657888 ! synapse organization GO:0050808 102 53 0,000 0,05937958 0,06575898 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,0604662 0,066932 ! regulation of translational initiation GO:0006446 87 54 0,000 0,0604662 0,06690169 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,0604662 0,0668714 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,0604662 0,06684115 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,0604662 0,06681091 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,0604662 0,06678071 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,0604662 0,06675053 ! membrane fusion GO:0006944 122 54 0,000 0,0604662 0,06672039 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,0604662 0,06669026 ! covalent chromatin modification GO:0016569 115 54 0,000 0,0604662 0,06666017 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,0604662 0,0666301 ! regulation of cell shape GO:0008360 142 54 0,000 0,0604662 0,06660006 ! RNA catabolic process GO:0006401 103 55 0,000 0,0615516 0,06776501 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,0615516 0,06773449 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,0615516 0,06770399 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,0615516 0,06767352 ! cell recognition GO:0008037 98 55 0,000 0,0615516 0,06764308 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,0615516 0,06761267 ! cell maturation GO:0048469 107 55 0,000 0,0615516 0,06758228 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,0615516 0,06755192 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,0615516 0,06752158 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,06263578 0,06868008 ! glucose catabolic process GO:0006007 88 56 0,000 0,06263578 0,06864927 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,06263578 0,06861848 ! regulation of DNA replication GO:0006275 105 56 0,000 0,06263578 0,06858772 ! RNA elongation GO:0006354 90 56 0,000 0,06263578 0,068557 ! chloride transport GO:0006821 102 57 0,000 0,06371874 0,06971109 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,06371874 0,06967989 ! muscle fiber development GO:0048747 131 57 0,000 0,06371874 0,06964871 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,06371874 0,06961756 ! heart morphogenesis GO:0003007 105 57 0,000 0,06371874 0,06958644 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,06371874 0,06955535 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,06371874 0,06952429 ! regulation of actin filament length GO:0030832 118 58 0,000 0,06480047 0,07067302 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,06480047 0,07064148 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,06480047 0,07060997 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,06480047 0,07057849 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,06480047 0,07054704 ! aging GO:0007568 112 58 0,000 0,06480047 0,07051561 ! gastrulation GO:0007369 122 58 0,000 0,06480047 0,07048422 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,06480047 0,07045285 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,06480047 0,07042151 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,06480047 0,0703902 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,06480047 0,07035891 ! maintenance of location GO:0051235 124 58 0,000 0,06480047 0,07032766 ! nuclear export GO:0051168 110 59 0,000 0,06588099 0,07146859 ! establishment of organelle localization GO:0051656 122 59 0,000 0,06588099 0,07143686 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,06696029 0,07257497 ! lipid modification GO:0030258 112 60 0,000 0,06696029 0,07254278 ! DNA catabolic process GO:0006308 94 60 0,000 0,06696029 0,07251063 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,06696029 0,0724785 ! adult behavior GO:0030534 104 60 0,000 0,06696029 0,0724464 ! kidney development GO:0001822 133 60 0,000 0,06696029 0,07241433 ! positive regulation of secretion GO:0051047 110 61 0,000 0,06803837 0,07354767 ! regulation of cellular component size GO:0032535 125 61 0,000 0,06803837 0,07351514 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,06803837 0,07348264 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,06803837 0,07345017 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,06803837 0,07341773 ! regulation of heart contraction GO:0008016 123 61 0,000 0,06803837 0,07338531 ! camera-type eye development GO:0043010 126 61 0,000 0,06803837 0,07335293 ! proton transport GO:0015992 117 61 0,000 0,06803837 0,07332057 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,06803837 0,07328824 ! viral reproductive process GO:0022415 132 62 0,000 0,06911523 0,07441539 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,06911523 0,0743826 ! tRNA processing GO:0008033 102 62 0,000 0,06911523 0,07434985 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,06911523 0,07431713 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,07019088 0,07544053 ! regulation of mitosis GO:0007088 112 63 0,000 0,07019088 0,07540736 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,07019088 0,07537421 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,07019088 0,07534109 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,07019088 0,07530801 ! hydrogen transport GO:0006818 121 64 0,000 0,07126532 0,07642721 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,07126532 0,07639367 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,07126532 0,07636017 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,07126532 0,07632669 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,07126532 0,07629324 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,07233855 0,07740827 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,07233855 0,07737438 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,07233855 0,07734052 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,07233855 0,07730668 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,07233855 0,07727288 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,07233855 0,07723911 ! ear development GO:0043583 114 66 0,000 0,07341057 0,07834951 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,07341057 0,07831529 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,07341057 0,07828111 ! gonad development GO:0008406 115 66 0,000 0,07341057 0,07824695 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,07341057 0,07821283 ! activation of MAPK activity GO:0000187 124 67 0,000 0,07448138 0,0793191 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,07448138 0,07928453 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,07448138 0,07925 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,07448138 0,0792155 ! secondary metabolic process GO:0019748 125 67 0,000 0,07448138 0,07918103 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,07448138 0,07914659 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,07555098 0,08024828 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,07555098 0,0802134 ! hexose catabolic process GO:0019320 113 68 0,000 0,07555098 0,08017856 ! extracellular matrix organization GO:0030198 146 68 0,000 0,07555098 0,08014374 ! detection of external stimulus GO:0009581 102 68 0,000 0,07555098 0,08010896 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,07555098 0,08007421 ! viral reproduction GO:0016032 142 68 0,000 0,07555098 0,08003948 ! regulation of lipase activity GO:0060191 137 68 0,000 0,07555098 0,08000479 ! adaptive immune response GO:0002250 126 68 0,000 0,07555098 0,07997012 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,07555098 0,07993549 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,07661938 0,08103079 ! lung development GO:0030324 165 69 0,000 0,07661938 0,08099573 ! urogenital system development GO:0001655 149 69 0,000 0,07661938 0,0809607 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,07661938 0,0809257 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,07661938 0,08089072 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,07661938 0,08085578 ! developmental maturation GO:0021700 128 69 0,000 0,07661938 0,08082087 ! single fertilization GO:0007338 83 69 0,000 0,07661938 0,08078599 ! cell redox homeostasis GO:0045454 114 70 0,000 0,07768657 0,08187588 ! germ cell development GO:0007281 133 70 0,000 0,07768657 0,08184057 ! activation of immune response GO:0002253 120 70 0,000 0,07768657 0,08180529 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,07768657 0,08177005 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,07875255 0,08285637 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,07875255 0,0828207 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,07875255 0,08278506 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,07875255 0,08274946 ! appendage morphogenesis GO:0035107 150 72 0,000 0,07981734 0,08383223 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,07981734 0,0837962 ! respiratory tube development GO:0030323 171 72 0,000 0,07981734 0,08376021 ! actin filament organization GO:0007015 167 72 0,000 0,07981734 0,08372424 ! B cell activation GO:0042113 179 72 0,000 0,07981734 0,08368831 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,07981734 0,08365241 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,07981734 0,08361654 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,07981734 0,0835807 ! appendage development GO:0048736 151 73 0,000 0,08088093 0,08465814 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,08088093 0,08462188 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,08088093 0,08458566 ! regulation of immune effector process GO:0002697 156 73 0,000 0,08088093 0,08454947 ! acute inflammatory response GO:0002526 118 74 0,000 0,08194331 0,0856234 ! amino acid transport GO:0006865 148 74 0,000 0,08194331 0,08558679 ! respiratory system development GO:0060541 175 74 0,000 0,08194331 0,08555022 ! organelle localization GO:0051640 155 74 0,000 0,08194331 0,08551367 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,0830045 0,08658411 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,0830045 0,08654716 ! reproductive structure development GO:0048608 131 75 0,000 0,0830045 0,08651023 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,0830045 0,08647334 ! eye development GO:0001654 155 75 0,000 0,0830045 0,08643648 ! axon guidance GO:0007411 162 75 0,000 0,0830045 0,08639966 ! rhythmic process GO:0048511 142 75 0,000 0,0830045 0,08636286 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,08406449 0,0874285 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,08406449 0,0873913 ! learning or memory GO:0007611 161 76 0,000 0,08406449 0,08735413 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,08406449 0,08731698 ! regulation of blood pressure GO:0008217 134 76 0,000 0,08406449 0,08727988 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,08406449 0,0872428 ! amine catabolic process GO:0009310 136 77 0,000 0,08512328 0,08830411 ! neurotransmitter transport GO:0006836 142 77 0,000 0,08512328 0,08826663 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,08512328 0,08822918 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,08512328 0,08819177 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,08512328 0,08815438 ! regulation of catabolic process GO:0009894 173 77 0,000 0,08512328 0,08811703 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,08618089 0,08917404 ! antigen processing and presentation GO:0019882 117 78 0,000 0,08618089 0,08913628 ! fertilization GO:0009566 99 78 0,000 0,08618089 0,08909856 ! blood coagulation GO:0007596 151 79 0,000 0,08723729 0,09015259 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,08723729 0,09011447 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,08723729 0,09007638 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,08723729 0,09003832 ! protein oligomerization GO:0051259 149 79 0,000 0,08723729 0,0900003 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,08723729 0,08996231 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,08829251 0,09101207 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,08829251 0,09097368 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,08829251 0,09093533 ! muscle cell differentiation GO:0042692 178 81 0,000 0,08934654 0,09198213 ! response to hypoxia GO:0001666 178 81 0,000 0,08934654 0,09194338 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,08934654 0,09190467 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,09039938 0,09294852 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,09145103 0,09399026 ! exocytosis GO:0006887 153 83 0,000 0,09145103 0,09395074 ! response to drug GO:0042493 149 83 0,000 0,09145103 0,09391125 ! response to oxygen levels GO:0070482 183 83 0,000 0,09145103 0,09387179 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,09145103 0,09383236 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,09145103 0,09379297 ! inorganic anion transport GO:0015698 156 83 0,000 0,09145103 0,09375361 ! T cell activation GO:0042110 189 84 0,000 0,09250149 0,09479075 ! response to nutrient GO:0007584 135 84 0,000 0,09250149 0,094751 ! digestion GO:0007586 130 84 0,000 0,09250149 0,09471129 ! hemostasis GO:0007599 165 85 0,000 0,09355077 0,09574551 ! negative regulation of transport GO:0051051 164 85 0,000 0,09355077 0,09570542 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,09355077 0,09566535 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,09355077 0,09562533 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,09355077 0,09558533 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,09355077 0,09554537 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,09355077 0,09550545 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,09459887 0,0965351 ! regulation of lyase activity GO:0051339 169 86 0,000 0,09459887 0,09649479 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,09564578 0,09752197 ! nucleosome assembly GO:0006334 126 87 0,000 0,09564578 0,09748128 ! regulation of protein transport GO:0051223 165 87 0,000 0,09564578 0,09744063 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 0,000 0,09669151 0,09846493 ! sensory perception of smell GO:0007608 117 88 0,000 0,09669151 0,0984239 ! chromatin assembly GO:0031497 128 88 0,000 0,09669151 0,09838291 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,09669151 0,09834195 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,09773606 0,09936296 ! regulation of DNA binding GO:0051101 167 89 0,000 0,09773606 0,09932163 ! cellular defense response GO:0006968 123 89 0,000 0,09773606 0,09928033 ! regulation of neurological system process GO:0031644 175 89 0,000 0,09773606 0,09923907 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,09877944 0,10025682 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,09877944 0,10021518 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,09982163 0,10123049 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,09982163 0,10118849 ! gland development GO:0048732 220 91 0,000 0,09982163 0,10114652 ! defense response to bacterium GO:0042742 112 91 0,000 0,09982163 0,10110458 ! bone development GO:0060348 206 92 0,000 0,10086265 0,10211665 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,10086265 0,10207434 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,10086265 0,10203208 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,1019025 0,10304131 ! amine transport GO:0015837 181 93 0,000 0,1019025 0,10299868 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,1019025 0,10295608 ! vitamin metabolic process GO:0006766 153 93 0,000 0,1019025 0,10291352 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,10294117 0,10391954 ! female pregnancy GO:0007565 166 94 0,000 0,10294117 0,10387662 ! sterol metabolic process GO:0016125 166 94 0,000 0,10294117 0,10383373 ! regulation of membrane potential GO:0042391 179 94 0,000 0,10294117 0,10379087 ! regulation of defense response GO:0031347 171 95 0,000 0,10397868 0,10479369 ! nucleosome organization GO:0034728 143 95 0,000 0,10397868 0,10475048 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,10397868 0,1047073 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,10397868 0,10466415 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,10397868 0,10462105 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,10397868 0,10457798 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,10397868 0,10453494 ! sex differentiation GO:0007548 171 96 0,000 0,10501501 0,10553338 ! regulation of T cell activation GO:0050863 175 96 0,000 0,10501501 0,10548999 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,10605017 0,10648605 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,10605017 0,1064423 ! transcription initiation GO:0006352 171 97 0,000 0,10605017 0,10639859 ! regulation of protein localization GO:0032880 188 97 0,000 0,10605017 0,10635491 ! leukocyte differentiation GO:0002521 232 98 0,000 0,10708416 0,10734781 ! forebrain development GO:0030900 210 98 0,000 0,10708416 0,10730377 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,10708416 0,10725978 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,10914865 0,10928284 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,10914865 0,10923808 ! positive regulation of immune response GO:0050778 175 100 0,000 0,10914865 0,10919334 ! hormone metabolic process GO:0042445 171 100 0,000 0,10914865 0,10914865