pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/54386-6-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 2,000 2,975E-06 6,842E-03 ! response to light stimulus GO:0009416 153 96 3,000 8,34E-06 9,591E-03 ! Ras protein signal transduction GO:0007265 162 100 3,000 9,808E-06 7,52E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 2,000 1,323E-05 7,607E-03 ! regulation of Rac protein signal transduction GO:0035020 8 6 1,000 2,7E-05 0,01242146 ! response to UV GO:0009411 75 46 2,000 3,32E-05 0,01272569 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,777E-05 0,01241104 ! negative regulation of telomere maintenance GO:0032205 9 7 1,000 3,777E-05 0,01085966 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 1,000 5,032E-05 0,01285991 GO:0046579|positive regulation of Ras protein signal transduction, ! induction of an organ GO:0001759 11 8 1,000 5,032E-05 0,01157392 ! regulation of telomere maintenance GO:0032204 10 8 1,000 5,032E-05 0,01052175 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 1,000 5,032E-05 9,645E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 1,000 6,464E-05 0,01143714 ! telomere maintenance via telomerase GO:0007004 12 9 1,000 6,464E-05 0,0106202 GO:0010833|telomere maintenance via telomere lengthening, ! thymus development GO:0048538 15 9 1,000 6,464E-05 9,912E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 7,765E-05 0,01116232 ! thyroid gland development GO:0030878 19 10 1,000 8,074E-05 0,01092339 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 8,074E-05 0,01031653 ! UV protection GO:0009650 14 10 1,000 8,074E-05 9,774E-03 ! RNA-dependent DNA replication GO:0006278 13 10 1,000 8,074E-05 9,285E-03 ! developmental induction GO:0031128 13 10 1,000 8,074E-05 8,843E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 8,074E-05 8,441E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 8,153E-05 8,153E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 9,39E-05 8,999E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 9,39E-05 8,639E-03 ! positive regulation of ligase activity GO:0051351 99 69 2,000 1,122E-04 9,928E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 1,000 1,182E-04 0,01007037 ! phosphoinositide-mediated signaling GO:0048015 109 71 2,000 1,222E-04 0,0100387 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 1,222E-04 9,693E-03 ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 1,396E-04 0,01070222 ! regulation of ligase activity GO:0051340 114 75 2,000 1,439E-04 0,01067382 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 1,627E-04 0,01169574 GO:0060675|ureteric bud morphogenesis, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 1,743E-04 0,01214529 GO:0010498|proteasomal protein catabolic process, ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 1,876E-04 0,01269061 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 2,085E-04 0,0137045 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 2,085E-04 0,01332382 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 1,000 2,142E-04 0,01331642 ! cellular response to unfolded protein GO:0034620 19 16 1,000 2,142E-04 0,01296599 GO:0030968|endoplasmic reticulum unfolded protein response, ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 2,159E-04 0,01273198 ! interphase GO:0051325 159 88 2,000 2,311E-04 0,01328686 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 2,426E-04 0,01360814 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 2,426E-04 0,01328414 ! axis specification GO:0009798 26 18 1,000 2,727E-04 0,01458487 ! visual learning GO:0008542 35 18 1,000 2,727E-04 0,01425339 ! activation of JUN kinase activity GO:0007257 23 18 1,000 2,727E-04 0,01393665 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 3,045E-04 0,01522487 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 3,733E-04 0,01826873 ! visual behavior GO:0007632 39 21 1,000 3,733E-04 0,01788813 ! cell aging GO:0007569 32 21 1,000 3,733E-04 0,01752307 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 3,733E-04 0,01717261 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 3,733E-04 0,01683589 ! ureteric bud development GO:0001657 32 22 1,000 4,103E-04 0,01814811 ! positive regulation of JUN kinase activity GO:0043507 28 22 1,000 4,103E-04 0,0178057 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 4,49E-04 0,0191243 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 4,49E-04 0,01877658 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 4,49E-04 0,01844129 ! telomere organization GO:0032200 32 23 1,000 4,49E-04 0,01811776 GO:0000723|telomere maintenance, ! insulin receptor signaling pathway GO:0008286 40 24 1,000 4,894E-04 0,01940778 ! fat cell differentiation GO:0045444 37 24 1,000 4,894E-04 0,01907883 ! base-excision repair GO:0006284 31 24 1,000 4,894E-04 0,01876085 ! regulation of JUN kinase activity GO:0043506 34 24 1,000 4,894E-04 0,0184533 ! regulation of chromosome organization GO:0033044 35 25 1,000 5,315E-04 0,01971788 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 5,753E-04 0,02100436 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 6,208E-04 0,02231155 ! negative regulation of protein transport GO:0051224 49 27 1,000 6,208E-04 0,0219683 ! inner ear morphogenesis GO:0042472 35 27 1,000 6,208E-04 0,02163544 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 7,169E-04 0,02461081 ! embryonic skeletal system morphogenesis GO:0048704 42 30 1,000 7,675E-04 0,02595919 ! maintenance of protein location in cell GO:0032507 60 31 1,000 8,197E-04 0,0273244 ! metanephros development GO:0001656 58 31 1,000 8,197E-04 0,02693405 ! cell fate specification GO:0001708 37 31 1,000 8,197E-04 0,0265547 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 8,736E-04 0,02790822 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 8,736E-04 0,02752591 ! ear morphogenesis GO:0042471 42 33 1,000 9,292E-04 0,0288816 ! negative regulation of DNA binding GO:0043392 54 33 1,000 9,292E-04 0,02849651 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 9,865E-04 0,02985414 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 9,865E-04 0,02946642 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 1,045E-03 0,03082576 ! keratinocyte differentiation GO:0030216 47 35 1,000 1,045E-03 0,03043556 ! maintenance of protein location GO:0045185 65 35 1,000 1,045E-03 0,03005511 ! negative regulation of binding GO:0051100 58 36 1,000 1,106E-03 0,03140387 ! learning GO:0007612 67 37 1,000 1,168E-03 0,03276606 ! striated muscle cell differentiation GO:0051146 54 38 1,000 1,232E-03 0,03414109 ! maintenance of location in cell GO:0051651 69 38 1,000 1,232E-03 0,03373464 ! JNK cascade GO:0007254 54 39 1,000 1,298E-03 0,03511039 ! response to calcium ion GO:0051592 58 40 1,000 1,365E-03 0,03649798 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 1,365E-03 0,03607846 ! inner ear development GO:0048839 57 40 1,000 1,365E-03 0,03566848 ! double-strand break repair GO:0006302 67 40 1,000 1,365E-03 0,03526771 ! epidermal cell differentiation GO:0009913 53 40 1,000 1,365E-03 0,03487585 ! epithelial cell differentiation GO:0030855 55 41 1,000 1,433E-03 0,03623109 ! regulation of JNK cascade GO:0046328 58 41 1,000 1,433E-03 0,03583728 ! receptor-mediated endocytosis GO:0006898 76 42 1,000 1,504E-03 0,03719337 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 1,504E-03 0,0367977 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 1,504E-03 0,03641035 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 1,504E-03 0,03603108 ! embryonic skeletal system development GO:0048706 56 42 1,000 1,504E-03 0,03565962 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 1,576E-03 0,03698651 ! response to insulin stimulus GO:0032868 63 43 1,000 1,576E-03 0,03661291 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 1,576E-03 0,03624678 ! positive regulation of cell cycle GO:0045787 77 45 1,000 1,725E-03 0,03927971 ! endocrine system development GO:0035270 83 47 1,000 1,88E-03 0,04239874 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 1,88E-03 0,0419871 ! regulation of DNA replication GO:0006275 75 48 1,000 1,96E-03 0,04335504 ! regulation of intracellular transport GO:0032386 78 49 1,000 2,042E-03 0,04473201 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 2,042E-03 0,04431001 ! maintenance of location GO:0051235 84 49 1,000 2,042E-03 0,0438959 ! ear development GO:0043583 72 50 1,000 2,125E-03 0,04526362 ! skeletal muscle fiber development GO:0048741 73 50 1,000 2,125E-03 0,04484835 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 2,21E-03 0,04621585 ! muscle fiber development GO:0048747 74 51 1,000 2,21E-03 0,04579949 ! aging GO:0007568 79 52 1,000 2,297E-03 0,0471667 ! nucleotide-excision repair GO:0006289 64 52 1,000 2,297E-03 0,0467493 ! skeletal system morphogenesis GO:0048705 78 53 1,000 2,385E-03 0,04811616 ! kidney development GO:0001822 90 53 1,000 2,385E-03 0,04769776 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 2,753E-03 0,05458435 ! activation of MAPK activity GO:0000187 84 59 1,000 2,946E-03 0,05792031 ! regulation of homeostatic process GO:0032844 105 60 1,000 3,045E-03 0,05936011 ! regulation of cellular response to stress GO:0080135 85 61 1,000 3,146E-03 0,06080571 ! urogenital system development GO:0001655 101 61 1,000 3,146E-03 0,060299 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 3,457E-03 0,0657137 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 3,564E-03 0,06718791 ! regulation of neuron differentiation GO:0045664 107 67 1,000 3,782E-03 0,07072046 ! learning or memory GO:0007611 123 68 1,000 3,893E-03 0,0722155 ! response to metal ion GO:0010038 103 70 1,000 4,121E-03 0,07581925 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 4,121E-03 0,07521751 ! muscle cell differentiation GO:0042692 104 71 1,000 4,237E-03 0,07672415 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 4,354E-03 0,07823432 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 4,354E-03 0,07762785 ! regulation of synaptic transmission GO:0050804 109 72 1,000 4,354E-03 0,07703072 ! negative regulation of transport GO:0051051 116 73 1,000 4,473E-03 0,07853036 ! tube morphogenesis GO:0035239 118 73 1,000 4,473E-03 0,07793543 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 4,473E-03 0,07734945 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 4,593E-03 0,07883887 ! response to inorganic substance GO:0010035 115 75 1,000 4,715E-03 0,08033169 ! response to unfolded protein GO:0006986 99 76 1,000 4,839E-03 0,08182779 ! regulation of protein transport GO:0051223 114 76 1,000 4,839E-03 0,0812305 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 119 77 1,000 4,963E-03 0,08272318 ! gland development GO:0048732 148 77 1,000 4,963E-03 0,08212805 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 4,963E-03 0,08154142 ! positive regulation of protein modification process GO:0031401 107 78 1,000 5,09E-03 0,08302434 ! response to protein stimulus GO:0051789 111 81 1,000 5,478E-03 0,08872327 ! regulation of neurological system process GO:0031644 122 81 1,000 5,478E-03 0,08810283 ! regulation of protein localization GO:0032880 132 85 1,000 6,015E-03 0,09608064 ! skeletal muscle tissue development GO:0007519 123 87 1,000 6,293E-03 0,09982162 GO:0060538|skeletal muscle organ development, ! anatomical structure homeostasis GO:0060249 136 88 1,000 6,434E-03 0,10135879 ! regulation of neurogenesis GO:0050767 153 89 1,000 6,576E-03 0,10289757 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 6,846E-03 0,10639308 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 6,846E-03 0,10567903 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 6,846E-03 0,1049745 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 6,846E-03 0,10427931 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 6,846E-03 0,10359326 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,846E-03 0,10291618 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 6,846E-03 0,10224789 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 6,846E-03 0,10158823 ! sleep GO:0030431 11 5 0,000 6,846E-03 0,10093702 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,846E-03 0,10029411 ! nucleotide-sugar transport GO:0015780 8 5 0,000 6,846E-03 0,09965934 ! regulation of interferon-beta production GO:0032648 5 5 0,000 6,846E-03 0,09903255 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 6,846E-03 0,0984136 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 6,846E-03 0,09780233 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 6,846E-03 0,09719861 ! tongue development GO:0043586 6 5 0,000 6,846E-03 0,0966023 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 6,846E-03 0,09601326 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,846E-03 0,09543137 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 6,846E-03 0,09485648 ! cobalt ion transport GO:0006824 9 5 0,000 6,846E-03 0,09428848 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 6,846E-03 0,09372723 ! SMAD protein complex assembly GO:0007183 9 5 0,000 6,846E-03 0,09317264 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 6,846E-03 0,09262456 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 6,846E-03 0,0920829 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 6,846E-03 0,09154753 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 6,846E-03 0,09101836 ! embryonic camera-type eye development GO:0031076 8 5 0,000 6,846E-03 0,09049526 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 6,846E-03 0,08997815 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 6,846E-03 0,08946691 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,846E-03 0,08896144 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,846E-03 0,08846166 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,846E-03 0,08796746 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 6,846E-03 0,08747875 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 6,846E-03 0,08699544 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,846E-03 0,08651745 ! malate metabolic process GO:0006108 7 5 0,000 6,846E-03 0,08604467 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 6,846E-03 0,08557704 ! behavioral response to pain GO:0048266 7 5 0,000 6,846E-03 0,08511446 ! clathrin coat assembly GO:0048268 11 5 0,000 6,846E-03 0,08465686 ! phototransduction, visible light GO:0007603 6 5 0,000 6,846E-03 0,08420415 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,846E-03 0,08375625 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 6,846E-03 0,0833131 ! mating behavior GO:0007617 6 5 0,000 6,846E-03 0,08287461 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,846E-03 0,08244071 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 6,846E-03 0,08201133 ! rhythmic behavior GO:0007622 12 5 0,000 6,846E-03 0,0815864 ! copulation GO:0007620 7 5 0,000 6,846E-03 0,08116585 ! glial cell fate commitment GO:0021781 12 5 0,000 6,846E-03 0,08074962 ! protein maturation by protein folding GO:0022417 12 5 0,000 6,846E-03 0,08033763 ! embryonic hemopoiesis GO:0035162 10 5 0,000 6,846E-03 0,07992982 ! regulation of potassium ion transport GO:0043266 9 5 0,000 6,846E-03 0,07952614 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 6,846E-03 0,07912651 ! apoptotic cell clearance GO:0043277 13 5 0,000 6,846E-03 0,07873088 ! lipoprotein particle clearance GO:0034381 9 5 0,000 6,846E-03 0,07833918 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 6,846E-03 0,07795136 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,846E-03 0,07756737 ! response to protozoan GO:0001562 9 5 0,000 6,846E-03 0,07718713 ! positive regulation of glycolysis GO:0045821 11 5 0,000 6,846E-03 0,07681061 ! lymph vessel development GO:0001945 7 5 0,000 6,846E-03 0,07643774 ! endochondral ossification GO:0001958 12 5 0,000 6,846E-03 0,07606848 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 6,846E-03 0,07570277 ! parathyroid gland development GO:0060017 8 5 0,000 6,846E-03 0,07534055 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 6,846E-03 0,07498179 ! anagen GO:0042640 6 5 0,000 6,846E-03 0,07462642 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 6,846E-03 0,07427441 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 6,846E-03 0,07392571 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 6,846E-03 0,07358026 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 6,846E-03 0,07323803 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 6,846E-03 0,07289896 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 6,846E-03 0,07256302 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 6,846E-03 0,07223016 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 6,846E-03 0,07190034 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 6,846E-03 0,07157352 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 6,846E-03 0,07124966 ! cardiac muscle fiber development GO:0048739 7 5 0,000 6,846E-03 0,07092872 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 6,846E-03 0,07061065 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 6,846E-03 0,07029543 ! neutrophil mediated immunity GO:0002446 6 5 0,000 6,846E-03 0,069983 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,846E-03 0,06967334 ! ovulation GO:0030728 6 5 0,000 6,846E-03 0,06936641 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 6,846E-03 0,06906217 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 6,846E-03 0,06876059 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 6,846E-03 0,06846163 ! response to pH GO:0009268 9 5 0,000 6,846E-03 0,06816526 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 6,846E-03 0,06787145 ! proline biosynthetic process GO:0006561 6 5 0,000 6,846E-03 0,06758015 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,846E-03 0,06729135 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 6,846E-03 0,067005 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,846E-03 0,06672108 ! polyol catabolic process GO:0046174 7 5 0,000 6,846E-03 0,06643956 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 6,846E-03 0,0661604 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,846E-03 0,06588358 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,846E-03 0,06560906 ! sister chromatid cohesion GO:0007062 9 5 0,000 6,846E-03 0,06533683 ! nerve growth factor processing GO:0032455 7 5 0,000 6,846E-03 0,06506684 ! urea metabolic process GO:0019627 6 5 0,000 6,846E-03 0,06479908 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 6,846E-03 0,06453351 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,846E-03 0,0642701 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 6,846E-03 0,06400884 ! neutrophil activation GO:0042119 5 5 0,000 6,846E-03 0,0637497 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 6,846E-03 0,06349264 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 6,846E-03 0,06323765 ! response to food GO:0032094 5 5 0,000 6,846E-03 0,0629847 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 6,846E-03 0,06273377 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,846E-03 0,06248482 ! paraxial mesoderm development GO:0048339 9 5 0,000 6,846E-03 0,06223785 ! forebrain neuron development GO:0021884 7 5 0,000 6,846E-03 0,06199282 ! melanosome organization GO:0032438 7 5 0,000 6,846E-03 0,06174971 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 6,846E-03 0,0615085 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 6,846E-03 0,06126917 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 6,846E-03 0,06103169 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,846E-03 0,06079604 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 6,846E-03 0,06056221 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 6,846E-03 0,06033017 ! nucleoside transport GO:0015858 6 5 0,000 6,846E-03 0,06009991 ! nucleoside salvage GO:0043174 7 5 0,000 6,846E-03 0,05987139 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 6,846E-03 0,0596446 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,846E-03 0,05941953 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 6,846E-03 0,05919615 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 6,846E-03 0,05897444 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,846E-03 0,05875439 ! early endosome to late endosome transport GO:0045022 11 5 0,000 6,846E-03 0,05853597 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,846E-03 0,05831917 ! depyrimidination GO:0045008 8 5 0,000 6,846E-03 0,05810397 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 6,846E-03 0,05789035 ! 5S class rRNA transcription GO:0042791 8 5 0,000 6,846E-03 0,0576783 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 6,846E-03 0,05746779 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,846E-03 0,05725882 ! neuronal ion channel clustering GO:0045161 7 5 0,000 6,846E-03 0,05705136 ! sodium ion homeostasis GO:0055078 6 5 0,000 6,846E-03 0,0568454 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 6,846E-03 0,05664092 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 6,846E-03 0,0564379 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 6,846E-03 0,05623634 ! monocyte differentiation GO:0030224 8 5 0,000 6,846E-03 0,05603621 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 6,846E-03 0,0558375 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 6,846E-03 0,0556402 ! centrosome duplication GO:0051298 5 5 0,000 6,846E-03 0,05544428 ! response to UV-C GO:0010225 6 5 0,000 6,846E-03 0,05524974 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 6,846E-03 0,05505656 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 6,846E-03 0,05486472 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 6,846E-03 0,05467422 ! regulation of dendrite development GO:0050773 12 5 0,000 6,846E-03 0,05448504 ! peptidyl-arginine modification GO:0018195 7 5 0,000 6,846E-03 0,05429716 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,846E-03 0,05411057 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 6,846E-03 0,05392526 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 6,846E-03 0,05374121 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 6,846E-03 0,05355842 ! regulation of dopamine secretion GO:0014059 12 5 0,000 6,846E-03 0,05337687 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 6,846E-03 0,05319654 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 6,846E-03 0,05301743 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 6,846E-03 0,05283951 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,846E-03 0,05266279 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 6,846E-03 0,05248725 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,846E-03 0,05231288 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 6,846E-03 0,05213965 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 6,846E-03 0,05196758 ! neural tube patterning GO:0021532 6 5 0,000 6,846E-03 0,05179663 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 6,846E-03 0,0516268 ! histone demethylation GO:0016577 9 5 0,000 6,846E-03 0,05145809 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 6,846E-03 0,05129047 ! regulation of sterol transport GO:0032371 7 5 0,000 6,846E-03 0,05112395 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 6,846E-03 0,0509585 ! enteric nervous system development GO:0048484 8 5 0,000 6,846E-03 0,05079411 ! establishment of planar polarity GO:0001736 6 5 0,000 6,846E-03 0,05063079 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 6,846E-03 0,05046851 ! muscle cell proliferation GO:0033002 8 5 0,000 6,846E-03 0,05030727 ! transcription termination GO:0006353 8 5 0,000 6,846E-03 0,05014706 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 6,846E-03 0,04998786 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 6,846E-03 0,04982967 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 6,846E-03 0,04967248 ! regulation of respiratory burst GO:0060263 8 5 0,000 6,846E-03 0,04951628 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 6,846E-03 0,04936105 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,846E-03 0,0492068 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,846E-03 0,04905351 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 6,846E-03 0,04890117 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 6,846E-03 0,04874977 ! apical protein localization GO:0045176 6 5 0,000 6,846E-03 0,04859931 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 6,846E-03 0,04844977 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 6,846E-03 0,04830115 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,846E-03 0,04815344 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 6,846E-03 0,04800663 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 6,846E-03 0,04786072 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 6,846E-03 0,04771568 ! triglyceride catabolic process GO:0019433 6 5 0,000 6,846E-03 0,04757153 ! glial cell migration GO:0008347 10 5 0,000 6,846E-03 0,04742824 ! determination of adult lifespan GO:0008340 8 5 0,000 6,846E-03 0,04728581 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 6,846E-03 0,04714424 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 6,846E-03 0,04700351 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,846E-03 0,04686362 ! somatic stem cell maintenance GO:0035019 13 5 0,000 6,846E-03 0,04672456 ! cerebellar cortex formation GO:0021697 6 5 0,000 6,846E-03 0,04658632 ! neural plate development GO:0001840 6 5 0,000 6,846E-03 0,0464489 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 6,846E-03 0,04631228 ! regulation of sensory perception GO:0051931 6 5 0,000 6,846E-03 0,04617647 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 6,846E-03 0,04604145 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 6,846E-03 0,04590722 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 6,846E-03 0,04577377 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 6,846E-03 0,04564109 ! sensory cilium assembly GO:0035058 6 5 0,000 6,846E-03 0,04550918 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 6,846E-03 0,04537803 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,846E-03 0,04524763 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 6,846E-03 0,04511798 ! spindle assembly GO:0051225 5 5 0,000 6,846E-03 0,04498907 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 6,846E-03 0,0448609 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 6,846E-03 0,04473345 ! protein amino acid prenylation GO:0018346 9 5 0,000 6,846E-03 0,04460673 ! organ regeneration GO:0031100 7 5 0,000 6,846E-03 0,04448072 ! NAD biosynthetic process GO:0009435 7 5 0,000 6,846E-03 0,04435542 ! carnitine metabolic process GO:0009437 5 5 0,000 6,846E-03 0,04423083 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 6,846E-03 0,04410693 ! cellular anion homeostasis GO:0030002 6 5 0,000 6,846E-03 0,04398373 GO:0055081|anion homeostasis, ! cell fate commitment GO:0045165 141 92 1,000 7,012E-03 0,04492593 ! response to oxidative stress GO:0006979 141 94 1,000 7,31E-03 0,0467031 ! regulation of binding GO:0051098 151 95 1,000 7,461E-03 0,04753563 ! tRNA transcription GO:0009304 11 6 0,000 8,21E-03 0,05216295 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 8,21E-03 0,05201925 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 8,21E-03 0,05187634 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 8,21E-03 0,05173422 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 8,21E-03 0,05159287 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 8,21E-03 0,05145229 ! regulation of helicase activity GO:0051095 11 6 0,000 8,21E-03 0,05131247 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 8,21E-03 0,05117341 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 8,21E-03 0,05103511 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 8,21E-03 0,05089754 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 8,21E-03 0,05076072 ! positive regulation of axon extension GO:0045773 8 6 0,000 8,21E-03 0,05062464 ! prostate gland development GO:0030850 9 6 0,000 8,21E-03 0,05048928 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 8,21E-03 0,05035464 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 8,21E-03 0,05022072 ! forebrain neuron differentiation GO:0021879 9 6 0,000 8,21E-03 0,0500875 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 8,21E-03 0,049955 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 8,21E-03 0,04982319 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 8,21E-03 0,04969208 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 8,21E-03 0,04956165 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 8,21E-03 0,04943191 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 8,21E-03 0,04930284 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 8,21E-03 0,04917445 ! neuron adhesion GO:0007158 9 6 0,000 8,21E-03 0,04904672 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 8,21E-03 0,04891966 ! establishment of tissue polarity GO:0007164 7 6 0,000 8,21E-03 0,04879325 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 8,21E-03 0,0486675 ! signal peptide processing GO:0006465 8 6 0,000 8,21E-03 0,04854239 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 8,21E-03 0,04841792 ! mRNA stabilization GO:0048255 15 6 0,000 8,21E-03 0,04829409 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 8,21E-03 0,04817089 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 8,21E-03 0,04804832 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 8,21E-03 0,04792637 ! opsonization GO:0008228 8 6 0,000 8,21E-03 0,04780504 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 8,21E-03 0,04768432 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 8,21E-03 0,0475642 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 8,21E-03 0,0474447 ! protein amino acid dealkylation GO:0008214 11 6 0,000 8,21E-03 0,04732579 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 8,21E-03 0,04720747 ! photoreceptor cell development GO:0042461 10 6 0,000 8,21E-03 0,04708975 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 8,21E-03 0,04697261 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 8,21E-03 0,04685605 ! mechanosensory behavior GO:0007638 8 6 0,000 8,21E-03 0,04674007 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 8,21E-03 0,04662466 ! negative regulation of endocytosis GO:0045806 8 6 0,000 8,21E-03 0,04650983 ! response to interferon-gamma GO:0034341 12 6 0,000 8,21E-03 0,04639555 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 8,21E-03 0,04628184 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 8,21E-03 0,04616868 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 8,21E-03 0,04605607 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 8,21E-03 0,04594401 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 8,21E-03 0,0458325 ! cGMP-mediated signaling GO:0019934 10 6 0,000 8,21E-03 0,04572152 ! activation of MAPKKK activity GO:0000185 10 6 0,000 8,21E-03 0,04561108 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 8,21E-03 0,04550118 ! thymic T cell selection GO:0045061 12 6 0,000 8,21E-03 0,0453918 ! protein lipoylation GO:0009249 10 6 0,000 8,21E-03 0,04528295 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 8,21E-03 0,04517462 ! pigment granule organization GO:0048753 11 6 0,000 8,21E-03 0,0450668 ! drug transport GO:0015893 6 6 0,000 8,21E-03 0,0449595 ! cysteine metabolic process GO:0006534 7 6 0,000 8,21E-03 0,04485271 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 8,21E-03 0,04474642 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 8,21E-03 0,04464064 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 8,21E-03 0,04453535 ! histidine metabolic process GO:0006547 6 6 0,000 8,21E-03 0,04443056 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 8,21E-03 0,04432627 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 8,21E-03 0,04422246 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 8,21E-03 0,04411913 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 8,21E-03 0,04401629 ! adenohypophysis development GO:0021984 10 6 0,000 8,21E-03 0,04391393 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 8,21E-03 0,04381204 ! hyperosmotic response GO:0006972 8 6 0,000 8,21E-03 0,04371062 ! microtubule nucleation GO:0007020 10 6 0,000 8,21E-03 0,04360967 ! ER overload response GO:0006983 7 6 0,000 8,21E-03 0,04350919 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 8,21E-03 0,04340917 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 8,21E-03 0,04330961 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 8,21E-03 0,0432105 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 8,21E-03 0,04311185 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 8,21E-03 0,04301364 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 8,21E-03 0,04291588 ! response to dietary excess GO:0002021 7 6 0,000 8,21E-03 0,04281857 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 8,21E-03 0,04272169 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 8,21E-03 0,04262526 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 8,21E-03 0,04252925 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 8,21E-03 0,04243368 ! glycerol ether catabolic process GO:0044269 8 6 0,000 8,21E-03 0,04233854 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 8,21E-03 0,04224382 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 8,21E-03 0,04214953 ! neuron apoptosis GO:0051402 8 6 0,000 8,21E-03 0,04205565 ! organic alcohol transport GO:0015850 9 6 0,000 8,21E-03 0,0419622 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 8,21E-03 0,04186916 ! T cell mediated immunity GO:0002456 12 6 0,000 8,21E-03 0,04177652 ! male sex determination GO:0030238 9 6 0,000 8,21E-03 0,0416843 ! carnitine transport GO:0015879 8 6 0,000 8,21E-03 0,04159249 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 8,21E-03 0,04150107 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 8,21E-03 0,04141006 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,21E-03 0,04131945 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 8,21E-03 0,04122923 ! positive regulation of exocytosis GO:0045921 6 6 0,000 8,21E-03 0,04113941 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 8,21E-03 0,04104998 ! parturition GO:0007567 12 6 0,000 8,21E-03 0,04096093 ! negative regulation of translational initiation GO:0045947 7 6 0,000 8,21E-03 0,04087227 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 8,21E-03 0,04078399 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 8,21E-03 0,0406961 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 8,21E-03 0,04060858 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 8,21E-03 0,04052144 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 8,21E-03 0,04043467 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 8,21E-03 0,04034827 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 8,21E-03 0,04026224 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 8,21E-03 0,04017657 ! macrophage differentiation GO:0030225 10 6 0,000 8,21E-03 0,04009127 ! astrocyte development GO:0014002 14 6 0,000 8,21E-03 0,04000633 ! hyaluronan metabolic process GO:0030212 6 6 0,000 8,21E-03 0,03992175 ! purine base biosynthetic process GO:0009113 14 6 0,000 8,21E-03 0,03983753 ! interaction with symbiont GO:0051702 8 6 0,000 8,21E-03 0,03975366 ! anterograde axon cargo transport GO:0008089 8 6 0,000 8,21E-03 0,03967015 ! skeletal muscle contraction GO:0003009 6 6 0,000 8,21E-03 0,03958698 ! eating behavior GO:0042755 6 6 0,000 8,21E-03 0,03950416 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 8,21E-03 0,03942169 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 8,21E-03 0,03933956 ! response to copper ion GO:0046688 9 6 0,000 8,21E-03 0,03925777 ! DNA topological change GO:0006265 8 6 0,000 8,21E-03 0,03917633 ! response to exogenous dsRNA GO:0043330 8 6 0,000 8,21E-03 0,03909522 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 8,21E-03 0,03901444 ! establishment of melanosome localization GO:0032401 9 6 0,000 8,21E-03 0,038934 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,21E-03 0,03885389 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 8,21E-03 0,0387741 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 8,21E-03 0,03869465 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 8,21E-03 0,03861552 ! nucleoside catabolic process GO:0009164 6 6 0,000 8,21E-03 0,03853671 ! gas homeostasis GO:0033483 11 6 0,000 8,21E-03 0,03845823 ! hair follicle maturation GO:0048820 7 6 0,000 8,21E-03 0,03838006 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 8,21E-03 0,03830221 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 8,21E-03 0,03822467 ! Schwann cell development GO:0014044 14 6 0,000 8,21E-03 0,03814745 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 8,21E-03 0,03807054 ! dendrite morphogenesis GO:0048813 9 6 0,000 8,21E-03 0,03799394 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 8,21E-03 0,03791765 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 8,21E-03 0,03784166 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 8,21E-03 0,03776598 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 8,21E-03 0,0376906 ! histone ubiquitination GO:0016574 7 6 0,000 8,21E-03 0,03761552 ! regulation of meiosis GO:0040020 10 6 0,000 8,21E-03 0,03754073 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 8,21E-03 0,03746625 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 8,21E-03 0,03739206 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 8,21E-03 0,03731816 ! regulation of mast cell activation GO:0033003 6 6 0,000 8,21E-03 0,03724455 ! membrane to membrane docking GO:0022614 12 6 0,000 8,21E-03 0,03717124 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 8,21E-03 0,03709821 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 8,21E-03 0,03702547 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 8,21E-03 0,03695301 ! receptor internalization GO:0031623 9 6 0,000 8,21E-03 0,03688084 ! neutrophil homeostasis GO:0001780 6 6 0,000 8,21E-03 0,03680895 ! coenzyme A metabolic process GO:0015936 9 6 0,000 8,21E-03 0,03673733 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 8,21E-03 0,036666 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 8,21E-03 0,03659494 ! protein deubiquitination GO:0016579 8 6 0,000 8,21E-03 0,03652416 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 8,21E-03 0,03645365 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 8,21E-03 0,03638341 ! peptidyl-histidine modification GO:0018202 9 6 0,000 8,21E-03 0,03631344 ! axonal fasciculation GO:0007413 9 6 0,000 8,21E-03 0,03624374 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 8,21E-03 0,03617431 ! thiamin metabolic process GO:0006772 6 6 0,000 8,21E-03 0,03610514 ! midbrain development GO:0030901 6 6 0,000 8,21E-03 0,03603624 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 8,21E-03 0,0359676 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 8,21E-03 0,03589922 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 8,21E-03 0,0358311 ! progesterone metabolic process GO:0042448 8 6 0,000 8,21E-03 0,03576324 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 8,21E-03 0,03569563 ! glycolipid catabolic process GO:0019377 13 6 0,000 8,21E-03 0,03562828 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 8,21E-03 0,03556118 ! positive regulation of glucose import GO:0046326 6 6 0,000 8,21E-03 0,03549434 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 8,21E-03 0,03542775 ! adult feeding behavior GO:0008343 6 6 0,000 8,21E-03 0,0353614 ! blastocyst growth GO:0001832 15 6 0,000 8,21E-03 0,03529531 ! pigment granule transport GO:0051904 12 6 0,000 8,21E-03 0,03522946 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 8,21E-03 0,03516385 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 8,21E-03 0,03509849 ! catecholamine transport GO:0051937 7 6 0,000 8,21E-03 0,03503337 ! organ or tissue specific immune response GO:0002251 7 6 0,000 8,21E-03 0,0349685 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 8,21E-03 0,03490386 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 8,21E-03 0,03483946 ! negative regulation of B cell activation GO:0050869 9 6 0,000 8,21E-03 0,0347753 ! protein prenylation GO:0018342 10 6 0,000 8,21E-03 0,03471138 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 8,21E-03 0,03464769 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 8,21E-03 0,03458423 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 8,21E-03 0,034521 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 8,21E-03 0,03445801 ! positive regulation of coagulation GO:0050820 11 6 0,000 8,21E-03 0,03439524 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 9,572E-03 0,0400285 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 9,572E-03 0,03995585 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 9,572E-03 0,03988347 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 9,572E-03 0,03981135 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 9,572E-03 0,03973948 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,572E-03 0,03966788 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 9,572E-03 0,03959654 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,572E-03 0,03952545 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 9,572E-03 0,03945461 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 9,572E-03 0,03938403 ! reproductive behavior GO:0019098 12 7 0,000 9,572E-03 0,0393137 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 9,572E-03 0,03924363 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 9,572E-03 0,0391738 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 9,572E-03 0,03910422 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 9,572E-03 0,03903488 ! oligopeptide transport GO:0006857 11 7 0,000 9,572E-03 0,0389658 ! protein amino acid sulfation GO:0006477 9 7 0,000 9,572E-03 0,03889695 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 9,572E-03 0,03882835 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 9,572E-03 0,03875999 ! RNA methylation GO:0001510 11 7 0,000 9,572E-03 0,03869187 ! pericardium development GO:0060039 8 7 0,000 9,572E-03 0,03862399 ! macrophage chemotaxis GO:0048246 10 7 0,000 9,572E-03 0,03855635 ! fibril organization GO:0043206 13 7 0,000 9,572E-03 0,03848894 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 9,572E-03 0,03842177 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 9,572E-03 0,03835483 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 9,572E-03 0,03828813 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 9,572E-03 0,03822166 ! lipoprotein transport GO:0042953 9 7 0,000 9,572E-03 0,03815541 ! cerebral cortex cell migration GO:0021795 11 7 0,000 9,572E-03 0,0380894 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 9,572E-03 0,03802362 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 9,572E-03 0,03795806 ! estrogen metabolic process GO:0008210 14 7 0,000 9,572E-03 0,03789273 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 9,572E-03 0,03782762 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 9,572E-03 0,03776273 ! chemosensory behavior GO:0007635 9 7 0,000 9,572E-03 0,03769807 ! microtubule bundle formation GO:0001578 8 7 0,000 9,572E-03 0,03763363 ! T-helper 1 type immune response GO:0042088 11 7 0,000 9,572E-03 0,03756941 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 9,572E-03 0,03750541 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 9,572E-03 0,03744162 ! leukocyte degranulation GO:0043299 10 7 0,000 9,572E-03 0,03737805 ! bile acid and bile salt transport GO:0015721 9 7 0,000 9,572E-03 0,0373147 ! reflex GO:0060004 12 7 0,000 9,572E-03 0,03725156 ! positive regulation of isotype switching GO:0045830 15 7 0,000 9,572E-03 0,03718864 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 9,572E-03 0,03712593 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,572E-03 0,03706342 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 9,572E-03 0,03700113 ! glycerolipid catabolic process GO:0046503 9 7 0,000 9,572E-03 0,03693905 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,572E-03 0,03687718 ! spinal cord patterning GO:0021511 7 7 0,000 9,572E-03 0,03681551 ! hemoglobin metabolic process GO:0020027 10 7 0,000 9,572E-03 0,03675405 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 9,572E-03 0,03669279 ! adrenal gland development GO:0030325 17 7 0,000 9,572E-03 0,03663174 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 9,572E-03 0,03657089 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 9,572E-03 0,03651024 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 9,572E-03 0,03644979 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 9,572E-03 0,03638954 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 9,572E-03 0,0363295 ! endosome organization GO:0007032 10 7 0,000 9,572E-03 0,03626964 ! thyroid hormone generation GO:0006590 11 7 0,000 9,572E-03 0,03620999 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 9,572E-03 0,03615053 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 9,572E-03 0,03609127 ! regulation of pigmentation during development GO:0048070 15 7 0,000 9,572E-03 0,0360322 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,572E-03 0,03597332 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 9,572E-03 0,03591464 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 9,572E-03 0,03585615 ! galactose metabolic process GO:0006012 10 7 0,000 9,572E-03 0,03579784 ! vesicle fusion GO:0006906 15 7 0,000 9,572E-03 0,03573973 ! intracellular pH reduction GO:0051452 10 7 0,000 9,572E-03 0,03568181 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 9,572E-03 0,03562407 ! organ growth GO:0035265 11 7 0,000 9,572E-03 0,03556652 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 9,572E-03 0,03550915 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 9,572E-03 0,03545197 ! Rac protein signal transduction GO:0016601 7 7 0,000 9,572E-03 0,03539497 ! retinol metabolic process GO:0042572 9 7 0,000 9,572E-03 0,03533816 ! behavioral fear response GO:0001662 13 7 0,000 9,572E-03 0,03528153 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 9,572E-03 0,03522508 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 9,572E-03 0,03516881 ! rRNA modification GO:0000154 12 7 0,000 9,572E-03 0,03511272 ! protein heterooligomerization GO:0051291 10 7 0,000 9,572E-03 0,03505681 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 9,572E-03 0,03500107 ! response to UV-B GO:0010224 11 7 0,000 9,572E-03 0,03494551 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 9,572E-03 0,03489013 ! protein retention in ER lumen GO:0006621 12 7 0,000 9,572E-03 0,03483493 ! intermediate filament organization GO:0045109 11 7 0,000 9,572E-03 0,0347799 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 9,572E-03 0,03472504 ! cardiac muscle cell development GO:0055013 9 7 0,000 9,572E-03 0,03467035 ! fibrinolysis GO:0042730 9 7 0,000 9,572E-03 0,03461584 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 9,572E-03 0,0345615 ! regulation of circadian rhythm GO:0042752 11 7 0,000 9,572E-03 0,03450733 ! B cell lineage commitment GO:0002326 17 7 0,000 9,572E-03 0,03445332 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 9,572E-03 0,03439949 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 9,572E-03 0,03434583 ! response to tropane GO:0014073 13 7 0,000 9,572E-03 0,03429233 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 9,572E-03 0,034239 ! melanosome localization GO:0032400 10 7 0,000 9,572E-03 0,03418583 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 9,572E-03 0,03413283 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 9,572E-03 0,03407999 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 9,572E-03 0,03402732 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 9,572E-03 0,03397481 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 9,572E-03 0,03392246 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 9,572E-03 0,03387027 ! mast cell activation GO:0045576 9 7 0,000 9,572E-03 0,03381824 ! multicellular organismal aging GO:0010259 11 7 0,000 9,572E-03 0,03376637 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 9,572E-03 0,03371466 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 9,572E-03 0,03366311 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 9,572E-03 0,03361172 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 9,572E-03 0,03356048 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 9,572E-03 0,0335094 ! establishment of nucleus localization GO:0040023 13 7 0,000 9,572E-03 0,03345847 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 9,572E-03 0,0334077 ! T cell lineage commitment GO:0002360 12 7 0,000 9,572E-03 0,03335708 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 9,572E-03 0,03330662 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 9,572E-03 0,03325631 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 9,572E-03 0,03320615 ! regulation of lipid transport GO:0032368 13 7 0,000 9,572E-03 0,03315614 ! response to tumor cell GO:0002347 12 7 0,000 9,572E-03 0,03310628 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 9,572E-03 0,03305657 ! neuroblast proliferation GO:0007405 13 7 0,000 9,572E-03 0,03300701 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 9,572E-03 0,0329576 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 9,572E-03 0,03290833 ! peptidyl-threonine modification GO:0018210 18 7 0,000 9,572E-03 0,03285922 ! diuresis GO:0030146 12 7 0,000 9,572E-03 0,03281024 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 9,572E-03 0,03276142 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 9,572E-03 0,03271274 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,572E-03 0,03266421 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 9,572E-03 0,03261581 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 9,572E-03 0,03256757 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 9,572E-03 0,03251946 ! melanin biosynthetic process GO:0042438 8 7 0,000 9,572E-03 0,0324715 ! regulation of synaptogenesis GO:0051963 10 7 0,000 9,572E-03 0,03242367 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 9,572E-03 0,03237599 ! dopamine biosynthetic process GO:0042416 15 7 0,000 9,572E-03 0,03232845 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 9,572E-03 0,03228105 ! lymph node development GO:0048535 9 7 0,000 9,572E-03 0,03223378 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 9,572E-03 0,03218666 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 9,572E-03 0,03213967 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 9,572E-03 0,03209282 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 9,572E-03 0,03204611 ! endosome to lysosome transport GO:0008333 10 7 0,000 9,572E-03 0,03199953 ! ATP catabolic process GO:0006200 10 7 0,000 9,572E-03 0,03195308 ! establishment of pigment granule localization GO:0051905 13 7 0,000 9,572E-03 0,03190677 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 9,572E-03 0,0318606 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 9,572E-03 0,03181456 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 9,572E-03 0,03176865 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 9,572E-03 0,03172287 ! muscle adaptation GO:0043500 12 7 0,000 9,572E-03 0,03167723 ! amino sugar catabolic process GO:0046348 9 7 0,000 9,572E-03 0,03163172 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 9,572E-03 0,03158633 ! retina homeostasis GO:0001895 9 7 0,000 9,572E-03 0,03154108 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 9,572E-03 0,03149596 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 9,572E-03 0,03145096 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 9,572E-03 0,0314061 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 9,572E-03 0,03136136 ! behavioral response to nicotine GO:0035095 11 7 0,000 9,572E-03 0,03131675 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 9,572E-03 0,03127226 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 9,572E-03 0,03122791 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01093228 0,03561507 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01093228 0,03556469 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01093228 0,03551446 ! axon extension GO:0048675 11 8 0,000 0,01093228 0,03546437 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01093228 0,03541442 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01093228 0,03536461 ! associative learning GO:0008306 15 8 0,000 0,01093228 0,03531494 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01093228 0,03526541 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01093228 0,03521602 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01093228 0,03516676 ! phosphate transport GO:0006817 10 8 0,000 0,01093228 0,03511765 ! N-glycan processing GO:0006491 12 8 0,000 0,01093228 0,03506867 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01093228 0,03501983 ! UTP metabolic process GO:0046051 8 8 0,000 0,01093228 0,03497112 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01093228 0,03492255 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01093228 0,03487411 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01093228 0,03482581 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01093228 0,03477764 ! succinate metabolic process GO:0006105 14 8 0,000 0,01093228 0,03472961 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01093228 0,03468171 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01093228 0,03463393 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01093228 0,0345863 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01093228 0,03453879 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01093228 0,03449141 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01093228 0,03444416 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01093228 0,03439704 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01093228 0,03435005 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01093228 0,03430319 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01093228 0,03425645 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01093228 0,03420985 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01093228 0,03416336 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01093228 0,03411701 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01093228 0,03407078 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01093228 0,03402468 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01093228 0,0339787 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01093228 0,03393284 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01093228 0,03388711 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01093228 0,0338415 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01093228 0,03379602 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01093228 0,03375065 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01093228 0,03370541 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01093228 0,03366029 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01093228 0,03361529 ! melanin metabolic process GO:0006582 12 8 0,000 0,01093228 0,03357041 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01093228 0,03352565 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01093228 0,03348101 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01093228 0,03343648 ! macrophage activation GO:0042116 12 8 0,000 0,01093228 0,03339208 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01093228 0,03334779 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01093228 0,03330362 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01093228 0,03325957 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01093228 0,03321564 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01093228 0,03317182 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01093228 0,03312811 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01093228 0,03308452 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01093228 0,03304105 ! ruffle organization GO:0031529 11 8 0,000 0,01093228 0,03299769 ! osteoblast development GO:0002076 13 8 0,000 0,01093228 0,03295444 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01093228 0,0329113 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01093228 0,03286828 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01093228 0,03282537 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01093228 0,03278258 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01093228 0,03273989 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01093228 0,03269732 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01093228 0,03265485 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01093228 0,0326125 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01093228 0,03257025 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01093228 0,03252812 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01093228 0,03248609 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01093228 0,03244418 ! segment specification GO:0007379 10 8 0,000 0,01093228 0,03240237 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01093228 0,03236066 ! cellular extravasation GO:0045123 11 8 0,000 0,01093228 0,03231907 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01093228 0,03227758 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01093228 0,0322362 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01093228 0,03219493 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01093228 0,03215376 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01093228 0,03211269 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01093228 0,03207173 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01093228 0,03203087 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01093228 0,03199012 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01093228 0,03194947 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01093228 0,03190893 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01093228 0,03186849 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01093228 0,03182815 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01093228 0,03178791 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01093228 0,03174777 ! icosanoid secretion GO:0032309 12 8 0,000 0,01093228 0,03170774 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01093228 0,0316678 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01093228 0,03162797 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01093228 0,03158824 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01093228 0,0315486 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01093228 0,03150907 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01093228 0,03146963 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01093228 0,0314303 ! sterol catabolic process GO:0016127 9 8 0,000 0,01093228 0,03139106 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01093228 0,03135192 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01093228 0,03131287 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01093228 0,03127393 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01093228 0,03123508 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01093228 0,03119632 ! prophase GO:0051324 11 8 0,000 0,01093228 0,03115767 ! S phase GO:0051320 8 8 0,000 0,01093228 0,0311191 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01093228 0,03108064 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01093228 0,03104227 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01093228 0,03100399 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01093228 0,03096581 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01093228 0,03092772 ! hormone catabolic process GO:0042447 13 8 0,000 0,01093228 0,03088973 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01093228 0,03085182 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01093228 0,03081402 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01093228 0,0307763 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01093228 0,03073868 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01093228 0,03070114 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01093228 0,0306637 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01093228 0,03062635 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01093228 0,0305891 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01093228 0,03055193 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01093228 0,03051485 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01093228 0,03047786 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01093228 0,03044096 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01093228 0,03040416 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01093228 0,03036744 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01229073 0,03409974 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01229073 0,03405865 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01229073 0,03401767 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01229073 0,03397678 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01229073 0,03393599 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01229073 0,0338953 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01229073 0,03385471 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01229073 0,03381421 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01229073 0,03377381 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01229073 0,03373351 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01229073 0,0336933 ! GTP metabolic process GO:0046039 9 9 0,000 0,01229073 0,03365319 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01229073 0,03361318 ! social behavior GO:0035176 14 9 0,000 0,01229073 0,03357326 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01229073 0,03353343 ! artery development GO:0060840 19 9 0,000 0,01229073 0,0334937 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01229073 0,03345406 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01229073 0,03341452 ! response to pain GO:0048265 16 9 0,000 0,01229073 0,03337507 ! protein complex disassembly GO:0043241 17 9 0,000 0,01229073 0,03333571 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01229073 0,03329644 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01229073 0,03325727 ! lung alveolus development GO:0048286 17 9 0,000 0,01229073 0,03321819 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01229073 0,0331792 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01229073 0,03314031 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01229073 0,0331015 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01229073 0,03306278 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01229073 0,03302416 ! protein targeting to ER GO:0045047 19 9 0,000 0,01229073 0,03298563 ! T cell selection GO:0045058 18 9 0,000 0,01229073 0,03294718 ! endoderm development GO:0007492 12 9 0,000 0,01229073 0,03290883 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01229073 0,03287056 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01229073 0,03283238 ! arginine catabolic process GO:0006527 10 9 0,000 0,01229073 0,03279429 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01229073 0,03275629 ! L-serine metabolic process GO:0006563 13 9 0,000 0,01229073 0,03271838 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01229073 0,03268056 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01229073 0,03264282 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01229073 0,03260517 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01229073 0,0325676 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01229073 0,03253013 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01229073 0,03249274 ! mannose metabolic process GO:0006013 9 9 0,000 0,01229073 0,03245543 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01229073 0,03241821 ! receptor clustering GO:0043113 15 9 0,000 0,01229073 0,03238108 ! epithelial cell development GO:0002064 10 9 0,000 0,01229073 0,03234403 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01229073 0,03230706 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01229073 0,03227018 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01229073 0,03223339 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01229073 0,03219668 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01229073 0,03216005 ! motor axon guidance GO:0008045 14 9 0,000 0,01229073 0,0321235 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01229073 0,03208704 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01229073 0,03205066 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01229073 0,03201436 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01229073 0,03197815 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01229073 0,03194201 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01229073 0,03190596 ! DNA ligation GO:0006266 14 9 0,000 0,01229073 0,03186999 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01229073 0,0318341 ! response to amine stimulus GO:0014075 13 9 0,000 0,01229073 0,03179829 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01229073 0,03176256 ! erythrocyte development GO:0048821 11 9 0,000 0,01229073 0,03172691 ! renal water homeostasis GO:0003091 14 9 0,000 0,01229073 0,03169135 ! postreplication repair GO:0006301 11 9 0,000 0,01229073 0,03165586 ! mRNA cleavage GO:0006379 13 9 0,000 0,01229073 0,03162045 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01229073 0,03158512 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01229073 0,03154987 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01229073 0,03151469 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01229073 0,0314796 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01229073 0,03144458 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01229073 0,03140965 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01229073 0,03137478 ! acid secretion GO:0046717 14 9 0,000 0,01229073 0,03134 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01229073 0,03130529 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01229073 0,03127066 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01229073 0,03123611 ! purine base metabolic process GO:0006144 18 9 0,000 0,01229073 0,03120163 ! oocyte differentiation GO:0009994 12 9 0,000 0,01229073 0,03116723 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01229073 0,03113291 ! spleen development GO:0048536 15 9 0,000 0,01229073 0,03109866 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01229073 0,03106448 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01229073 0,03103039 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01229073 0,03099636 ! detection of calcium ion GO:0005513 13 9 0,000 0,01229073 0,03096241 ! blastocyst formation GO:0001825 12 9 0,000 0,01229073 0,03092853 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01229073 0,03089473 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01229073 0,03086101 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01229073 0,03082735 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01229073 0,03079377 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01229073 0,03076026 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01229073 0,03072683 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01229073 0,03069346 ! prepulse inhibition GO:0060134 14 9 0,000 0,01229073 0,03066017 ! embryonic placenta development GO:0001892 12 9 0,000 0,01229073 0,03062696 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01229073 0,03059381 ! insulin secretion GO:0030073 17 9 0,000 0,01229073 0,03056074 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01229073 0,03052773 ! response to nicotine GO:0035094 16 9 0,000 0,01229073 0,0304948 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01229073 0,03046194 ! nucleus localization GO:0051647 15 9 0,000 0,01229073 0,03042915 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01229073 0,03039643 ! localization within membrane GO:0051668 15 9 0,000 0,01229073 0,03036378 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,0136474 0,0336792 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,0136474 0,0336431 ! neuron fate specification GO:0048665 11 10 0,000 0,0136474 0,03360708 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,0136474 0,03357114 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,0136474 0,03353527 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,0136474 0,03349948 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,0136474 0,03346377 ! synapsis GO:0007129 13 10 0,000 0,0136474 0,03342813 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,0136474 0,03339257 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,0136474 0,03335708 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,0136474 0,03332167 ! sulfate transport GO:0008272 12 10 0,000 0,0136474 0,03328633 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,0136474 0,03325107 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,0136474 0,03321589 ! androgen metabolic process GO:0008209 13 10 0,000 0,0136474 0,03318077 ! phospholipid efflux GO:0033700 16 10 0,000 0,0136474 0,03314574 ! hippocampus development GO:0021766 19 10 0,000 0,0136474 0,03311077 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,0136474 0,03307588 ! blood vessel remodeling GO:0001974 21 10 0,000 0,0136474 0,03304107 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,0136474 0,03300632 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,0136474 0,03297165 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,0136474 0,03293705 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,0136474 0,03290253 ! pathogenesis GO:0009405 13 10 0,000 0,0136474 0,03286808 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,0136474 0,03283369 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0136474 0,03279939 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,0136474 0,03276515 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,0136474 0,03273098 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,0136474 0,03269689 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,0136474 0,03266286 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,0136474 0,03262891 ! melanocyte differentiation GO:0030318 15 10 0,000 0,0136474 0,03259503 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,0136474 0,03256122 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,0136474 0,03252747 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0136474 0,0324938 ! response to X-ray GO:0010165 16 10 0,000 0,0136474 0,0324602 ! B cell proliferation GO:0042100 14 10 0,000 0,0136474 0,03242667 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,0136474 0,0323932 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,0136474 0,03235981 ! forebrain cell migration GO:0021885 17 10 0,000 0,0136474 0,03232648 ! lipid digestion GO:0044241 15 10 0,000 0,0136474 0,03229322 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,0136474 0,03226003 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,0136474 0,03222691 ! entry into host cell GO:0030260 20 10 0,000 0,0136474 0,03219386 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,0136474 0,03216087 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,0136474 0,03212796 ! negative regulation of ossification GO:0030279 19 10 0,000 0,0136474 0,0320951 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,0136474 0,03206232 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,0136474 0,0320296 ! regulation of bone resorption GO:0045124 24 10 0,000 0,0136474 0,03199695 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,0136474 0,03196437 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,0136474 0,03193185 ! regulation of organ growth GO:0046620 11 10 0,000 0,0136474 0,0318994 ! response to dsRNA GO:0043331 18 10 0,000 0,0136474 0,03186702 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0136474 0,0318347 ! embryonic axis specification GO:0000578 12 10 0,000 0,0136474 0,03180244 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,0136474 0,03177026 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,0136474 0,03173813 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,0136474 0,03170607 ! cranial nerve development GO:0021545 12 10 0,000 0,0136474 0,03167408 ! fucose catabolic process GO:0019317 16 10 0,000 0,0136474 0,03164215 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,0136474 0,03161028 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,0136474 0,03157848 ! protein sumoylation GO:0016925 12 10 0,000 0,0136474 0,03154675 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,0136474 0,03151507 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0136474 0,03148346 ! zymogen activation GO:0031638 14 10 0,000 0,0136474 0,03145192 ! salivary gland development GO:0007431 22 10 0,000 0,0136474 0,03142043 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0136474 0,03138901 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,0136474 0,03135765 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,0136474 0,03132636 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,0136474 0,03129513 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,0136474 0,03126396 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,0136474 0,03123285 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0136474 0,0312018 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,0136474 0,03117082 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,0136474 0,03113989 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,0136474 0,03110903 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,0136474 0,03107823 ! detection of bacterium GO:0016045 10 10 0,000 0,0136474 0,03104749 ! embryonic gut development GO:0048566 11 10 0,000 0,0136474 0,03101681 ! activation of innate immune response GO:0002218 10 10 0,000 0,0136474 0,03098619 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,0136474 0,03095563 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,0136474 0,03092514 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,0136474 0,0308947 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,0136474 0,03086432 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,0136474 0,030834 ! rRNA transcription GO:0009303 17 11 0,000 0,01500228 0,03386186 ! respiratory burst GO:0045730 14 11 0,000 0,01500228 0,03382866 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01500228 0,03379553 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01500228 0,03376246 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01500228 0,03372946 ! virus-host interaction GO:0019048 17 11 0,000 0,01500228 0,03369652 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01500228 0,03366364 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01500228 0,03363083 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01500228 0,03359809 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01500228 0,0335654 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01500228 0,03353279 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01500228 0,03350023 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01500228 0,03346774 ! mating GO:0007618 14 11 0,000 0,01500228 0,03343531 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01500228 0,03340294 ! T cell proliferation GO:0042098 20 11 0,000 0,01500228 0,03337063 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01500228 0,03333839 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01500228 0,03330621 ! bone resorption GO:0045453 16 11 0,000 0,01500228 0,03327409 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01500228 0,03324204 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01500228 0,03321004 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01500228 0,03317811 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01500228 0,03314624 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01500228 0,03311443 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01500228 0,03308268 ! syncytium formation GO:0006949 15 11 0,000 0,01500228 0,03305099 ! plasma membrane organization GO:0007009 18 11 0,000 0,01500228 0,03301936 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01500228 0,0329878 ! focal adhesion formation GO:0048041 24 11 0,000 0,01500228 0,03295629 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01500228 0,03292484 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01500228 0,03289346 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01500228 0,03286213 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01500228 0,03283086 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01500228 0,03279965 ! adult heart development GO:0007512 11 11 0,000 0,01500228 0,03276851 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01500228 0,03273742 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01500228 0,03270638 ! temperature homeostasis GO:0001659 16 11 0,000 0,01500228 0,03267541 ! L-glutamate transport GO:0015813 16 11 0,000 0,01500228 0,0326445 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01500228 0,03261364 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01500228 0,03258285 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01500228 0,03255211 ! stem cell development GO:0048864 29 11 0,000 0,01500228 0,03252143 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01500228 0,03249081 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01500228 0,03246024 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01500228 0,03242973 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01500228 0,03239928 ! vasoconstriction GO:0042310 15 11 0,000 0,01500228 0,03236889 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01500228 0,03233855 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01500228 0,03230827 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01500228 0,03227805 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01500228 0,03224788 ! ribosome assembly GO:0042255 13 11 0,000 0,01500228 0,03221777 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01500228 0,03218772 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01500228 0,03215772 ! chromatin silencing GO:0006342 19 11 0,000 0,01500228 0,03212778 ! nucleosome positioning GO:0016584 13 11 0,000 0,01500228 0,03209789 ! T cell homeostasis GO:0043029 20 11 0,000 0,01500228 0,03206806 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01500228 0,03203829 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01500228 0,03200857 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01500228 0,0319789 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01500228 0,03194929 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01500228 0,03191974 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01500228 0,03189024 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01500228 0,03186079 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01500228 0,0318314 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01500228 0,03180206 ! male genitalia development GO:0030539 13 11 0,000 0,01500228 0,03177278 ! cholesterol efflux GO:0033344 19 11 0,000 0,01500228 0,03174355 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01500228 0,03171437 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01500228 0,03168525 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01500228 0,03165618 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01500228 0,03162716 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01500228 0,0315982 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01500228 0,03156929 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01500228 0,03154044 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01500228 0,03151163 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01500228 0,03148288 ! lysogeny GO:0030069 18 11 0,000 0,01500228 0,03145418 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01500228 0,03142553 ! acrosome reaction GO:0007340 13 11 0,000 0,01500228 0,03139694 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01500228 0,0313684 ! lactation GO:0007595 20 12 0,000 0,01635537 0,03416654 ! reproductive cellular process GO:0048610 14 12 0,000 0,01635537 0,03413553 ! tRNA modification GO:0006400 14 12 0,000 0,01635537 0,03410459 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01635537 0,03407369 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01635537 0,03404286 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01635537 0,03401208 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01635537 0,03398135 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01635537 0,03395068 ! non-recombinational repair GO:0000726 19 12 0,000 0,01635537 0,03392007 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01635537 0,03388951 ! peroxisomal transport GO:0043574 21 12 0,000 0,01635537 0,03385901 ! cartilage condensation GO:0001502 18 12 0,000 0,01635537 0,03382856 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01635537 0,03379816 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01635537 0,03376783 ! heart looping GO:0001947 15 12 0,000 0,01635537 0,03373754 ! palate development GO:0060021 15 12 0,000 0,01635537 0,03370731 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01635537 0,03367713 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01635537 0,03364701 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01635537 0,03361694 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01635537 0,03358693 ! arginine metabolic process GO:0006525 13 12 0,000 0,01635537 0,03355696 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01635537 0,03352706 ! methionine metabolic process GO:0006555 13 12 0,000 0,01635537 0,0334972 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01635537 0,0334674 ! Golgi organization GO:0007030 18 12 0,000 0,01635537 0,03343765 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01635537 0,03340796 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01635537 0,03337831 ! monoamine transport GO:0015844 13 12 0,000 0,01635537 0,03334872 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01635537 0,03331918 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01635537 0,0332897 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01635537 0,03326026 ! L-amino acid transport GO:0015807 20 12 0,000 0,01635537 0,03323088 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01635537 0,03320155 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01635537 0,03317227 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01635537 0,03314305 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01635537 0,03311387 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01635537 0,03308475 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01635537 0,03305567 ! cerebellum development GO:0021549 13 12 0,000 0,01635537 0,03302665 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01635537 0,03299768 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01635537 0,03296876 ! histone acetylation GO:0016573 23 12 0,000 0,01635537 0,03293989 ! histone methylation GO:0016571 15 12 0,000 0,01635537 0,03291107 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01635537 0,03288231 ! gland morphogenesis GO:0022612 23 12 0,000 0,01635537 0,03285359 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01635537 0,03282492 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01635537 0,0327963 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01635537 0,03276773 ! response to gamma radiation GO:0010332 20 12 0,000 0,01635537 0,03273921 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01635537 0,03271075 ! intestinal absorption GO:0050892 19 12 0,000 0,01635537 0,03268233 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01635537 0,03265396 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01635537 0,03262564 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01635537 0,03259736 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01635537 0,03256914 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01635537 0,03254097 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01635537 0,03251284 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01635537 0,03248476 ! microspike assembly GO:0030035 23 12 0,000 0,01635537 0,03245674 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01635537 0,03242876 ! response to cold GO:0009409 14 12 0,000 0,01635537 0,03240082 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01770669 0,03504766 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01770669 0,03501753 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01770669 0,03498744 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01770669 0,03495741 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01770669 0,03492743 ! water transport GO:0006833 17 13 0,000 0,01770669 0,0348975 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01770669 0,03486762 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01770669 0,03483779 ! lipid localization GO:0010876 24 13 0,000 0,01770669 0,03480802 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01770669 0,03477829 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01770669 0,03474862 ! organelle fusion GO:0048284 28 13 0,000 0,01770669 0,034719 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01770669 0,03468942 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01770669 0,0346599 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01770669 0,03463043 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01770669 0,034601 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01770669 0,03457163 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01770669 0,03454231 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01770669 0,03451304 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01770669 0,03448381 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01770669 0,03445464 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01770669 0,03442551 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01770669 0,03439644 ! NAD metabolic process GO:0019674 21 13 0,000 0,01770669 0,03436741 ! exocrine system development GO:0035272 27 13 0,000 0,01770669 0,03433843 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01770669 0,0343095 ! bone mineralization GO:0030282 15 13 0,000 0,01770669 0,03428062 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01770669 0,03425179 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01770669 0,03422301 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01770669 0,03419428 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01770669 0,03416559 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01770669 0,03413695 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01770669 0,03410836 ! genitalia development GO:0048806 15 13 0,000 0,01770669 0,03407982 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01770669 0,03405132 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01770669 0,03402288 ! cellular pigmentation GO:0033059 24 13 0,000 0,01770669 0,03399448 ! tissue regeneration GO:0042246 21 13 0,000 0,01770669 0,03396612 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01770669 0,03393782 ! cofactor transport GO:0051181 19 13 0,000 0,01770669 0,03390956 ! NADP metabolic process GO:0006739 18 13 0,000 0,01770669 0,03388135 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01770669 0,03385319 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01770669 0,03382507 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01770669 0,033797 ! gas transport GO:0015669 18 13 0,000 0,01770669 0,03376897 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01770669 0,033741 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01770669 0,03371306 ! regulation of axon extension GO:0030516 23 13 0,000 0,01770669 0,03368518 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01770669 0,03365734 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01770669 0,03362955 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01770669 0,0336018 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01770669 0,0335741 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01770669 0,03354644 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01770669 0,03351883 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,01905622 0,03604384 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,01905622 0,03601423 ! superoxide anion generation GO:0042554 18 14 0,000 0,01905622 0,03598466 ! neuron maturation GO:0042551 21 14 0,000 0,01905622 0,03595514 ! regulation of S phase GO:0033261 18 14 0,000 0,01905622 0,03592567 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,01905622 0,03589624 ! myotube differentiation GO:0014902 21 14 0,000 0,01905622 0,03586687 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01905622 0,03583754 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,01905622 0,03580826 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01905622 0,03577903 ! inositol metabolic process GO:0006020 20 14 0,000 0,01905622 0,03574985 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01905622 0,03572071 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01905622 0,03569162 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01905622 0,03566258 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01905622 0,03563359 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01905622 0,03560464 ! response to cAMP GO:0051591 19 14 0,000 0,01905622 0,03557574 ! limbic system development GO:0021761 25 14 0,000 0,01905622 0,03554689 ! startle response GO:0001964 21 14 0,000 0,01905622 0,03551808 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01905622 0,03548932 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01905622 0,03546061 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01905622 0,03543194 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01905622 0,03540332 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01905622 0,03537475 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,01905622 0,03534622 ! glycine metabolic process GO:0006544 22 14 0,000 0,01905622 0,03531774 ! pituitary gland development GO:0021983 23 14 0,000 0,01905622 0,0352893 ! cellular response to starvation GO:0009267 21 14 0,000 0,01905622 0,03526091 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01905622 0,03523257 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01905622 0,03520427 ! regulation of heart rate GO:0002027 23 14 0,000 0,01905622 0,03517601 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01905622 0,03514781 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,01905622 0,03511964 ! embryo implantation GO:0007566 27 14 0,000 0,01905622 0,03509152 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01905622 0,03506345 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01905622 0,03503542 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01905622 0,03500744 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01905622 0,0349795 ! axon cargo transport GO:0008088 27 14 0,000 0,01905622 0,03495161 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01905622 0,03492376 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01905622 0,03489595 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01905622 0,03486819 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01905622 0,03484047 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01905622 0,0348128 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01905622 0,03478517 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01905622 0,03475758 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01905622 0,03473004 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01905622 0,03470254 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01905622 0,03467509 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01905622 0,03464768 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01905622 0,03462031 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01905622 0,03459299 ! muscle maintenance GO:0046716 19 14 0,000 0,01905622 0,03456571 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01905622 0,03453847 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01905622 0,03451127 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01905622 0,03448412 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01905622 0,03445701 ! cell killing GO:0001906 20 14 0,000 0,01905622 0,03442994 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,01905622 0,03440292 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,01905622 0,03437593 ! cilium assembly GO:0042384 20 14 0,000 0,01905622 0,03434899 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01905622 0,03432209 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02040398 0,03672078 ! positive regulation of cell size GO:0045793 20 15 0,000 0,02040398 0,03669207 ! metencephalon development GO:0022037 19 15 0,000 0,02040398 0,03666341 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02040398 0,03663478 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02040398 0,03660621 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02040398 0,03657768 ! skin development GO:0043588 25 15 0,000 0,02040398 0,03654919 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02040398 0,03652075 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02040398 0,03649235 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02040398 0,03646399 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02040398 0,03643568 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02040398 0,03640742 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02040398 0,03637919 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02040398 0,03635101 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02040398 0,03632288 ! adult walking behavior GO:0007628 25 15 0,000 0,02040398 0,03629479 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02040398 0,03626674 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02040398 0,03623873 ! myoblast differentiation GO:0045445 27 15 0,000 0,02040398 0,03621077 ! centrosome cycle GO:0007098 16 15 0,000 0,02040398 0,03618285 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02040398 0,03615498 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02040398 0,03612714 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02040398 0,03609935 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02040398 0,03607161 ! cerebral cortex development GO:0021987 29 15 0,000 0,02040398 0,0360439 ! response to osmotic stress GO:0006970 22 15 0,000 0,02040398 0,03601624 ! vesicle coating GO:0006901 25 15 0,000 0,02040398 0,03598862 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02040398 0,03596104 ! DNA integration GO:0015074 22 15 0,000 0,02040398 0,03593351 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02040398 0,03590601 ! peptide secretion GO:0002790 27 15 0,000 0,02040398 0,03587856 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02040398 0,03585115 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02040398 0,03582379 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02040398 0,03579646 ! neuron recognition GO:0008038 22 15 0,000 0,02040398 0,03576918 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02040398 0,03574193 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02040398 0,03571473 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02040398 0,03568757 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02040398 0,03566046 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02040398 0,03563338 ! biomineral formation GO:0031214 18 15 0,000 0,02040398 0,03560634 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02040398 0,03557935 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02040398 0,03555239 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02040398 0,03552548 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02040398 0,03549861 ! organic cation transport GO:0015695 19 15 0,000 0,02040398 0,03547178 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02040398 0,03544498 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02040398 0,03541823 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02040398 0,03539152 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02040398 0,03536485 ! defense response to virus GO:0051607 27 15 0,000 0,02040398 0,03533822 ! peptide hormone processing GO:0016486 19 15 0,000 0,02040398 0,03531163 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02040398 0,03528508 ! protein secretion GO:0009306 27 16 0,000 0,02174997 0,03758446 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02174997 0,03755625 ! hormone secretion GO:0046879 25 16 0,000 0,02174997 0,03752807 ! bone remodeling GO:0046849 24 16 0,000 0,02174997 0,03749994 ! endothelial cell migration GO:0043542 22 16 0,000 0,02174997 0,03747185 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02174997 0,0374438 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02174997 0,0374158 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02174997 0,03738783 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02174997 0,03735991 ! glial cell development GO:0021782 24 16 0,000 0,02174997 0,03733203 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02174997 0,03730419 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02174997 0,0372764 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02174997 0,03724864 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02174997 0,03722092 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02174997 0,03719325 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02174997 0,03716562 ! fructose metabolic process GO:0006000 20 16 0,000 0,02174997 0,03713803 ! regulation of protein binding GO:0043393 27 16 0,000 0,02174997 0,03711048 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02174997 0,03708297 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02174997 0,0370555 ! protein export from nucleus GO:0006611 24 16 0,000 0,02174997 0,03702807 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02174997 0,03700068 ! DNA replication initiation GO:0006270 25 16 0,000 0,02174997 0,03697334 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02174997 0,03694603 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02174997 0,03691876 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02174997 0,03689154 ! diencephalon development GO:0021536 25 16 0,000 0,02174997 0,03686435 ! oogenesis GO:0048477 23 16 0,000 0,02174997 0,0368372 ! neural crest cell migration GO:0001755 24 16 0,000 0,02174997 0,0368101 ! G1 phase GO:0051318 27 16 0,000 0,02174997 0,03678303 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02174997 0,036756 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02174997 0,03672902 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02174997 0,03670207 ! steroid catabolic process GO:0006706 22 16 0,000 0,02174997 0,03667516 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02174997 0,03664829 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02174997 0,03662147 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02174997 0,03659468 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02174997 0,03656793 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02174997 0,03654121 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02174997 0,03651454 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02174997 0,03648791 ! nerve development GO:0021675 18 16 0,000 0,02174997 0,03646131 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02174997 0,03643476 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02174997 0,03640824 ! negative regulation of translation GO:0017148 22 16 0,000 0,02174997 0,03638176 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02309418 0,03860219 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02309418 0,03857415 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02309418 0,03854616 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02309418 0,03851821 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02309418 0,0384903 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02309418 0,03846243 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02309418 0,03843459 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02309418 0,0384068 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02309418 0,03837905 ! signal complex assembly GO:0007172 29 17 0,000 0,02309418 0,03835134 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02309418 0,03832367 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02309418 0,03829604 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02309418 0,03826845 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02309418 0,0382409 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02309418 0,03821339 ! memory GO:0007613 25 17 0,000 0,02309418 0,03818592 ! keratinization GO:0031424 17 17 0,000 0,02309418 0,03815848 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02309418 0,03813109 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,02309418 0,03810374 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02309418 0,03807642 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,02309418 0,03804915 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02309418 0,03802191 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02309418 0,03799471 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02309418 0,03796756 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02309418 0,03794044 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02309418 0,03791335 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02309418 0,03788631 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02309418 0,03785931 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02309418 0,03783234 ! membrane budding GO:0006900 29 17 0,000 0,02309418 0,03780542 ! heme metabolic process GO:0042168 27 17 0,000 0,02309418 0,03777853 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02309418 0,03775168 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02309418 0,03772486 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02309418 0,03769809 ! body fluid secretion GO:0007589 27 17 0,000 0,02309418 0,03767135 ! stem cell differentiation GO:0048863 36 17 0,000 0,02309418 0,03764466 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02309418 0,037618 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02309418 0,03759137 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02309418 0,03756479 ! sensory perception of pain GO:0019233 23 17 0,000 0,02309418 0,03753824 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02309418 0,03751173 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02309418 0,03748526 ! synaptogenesis GO:0007416 24 17 0,000 0,02309418 0,03745882 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02309418 0,03743242 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02309418 0,03740606 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02309418 0,03737974 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02309418 0,03735345 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02309418 0,0373272 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02309418 0,03730099 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02309418 0,03727481 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02309418 0,03724867 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02309418 0,03722257 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02443662 0,0393587 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02443662 0,03933116 ! positive regulation of translation GO:0045727 28 18 0,000 0,02443662 0,03930365 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02443662 0,03927619 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02443662 0,03924876 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02443662 0,03922137 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02443662 0,03919402 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02443662 0,03916671 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02443662 0,03913943 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02443662 0,0391122 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02443662 0,039085 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02443662 0,03905784 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02443662 0,03903071 ! pancreas development GO:0031016 26 18 0,000 0,02443662 0,03900363 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,02443662 0,03897658 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02443662 0,03894957 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02443662 0,03892259 ! response to retinoic acid GO:0032526 25 18 0,000 0,02443662 0,03889566 ! pigmentation during development GO:0048066 31 18 0,000 0,02443662 0,03886876 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02443662 0,0388419 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02443662 0,03881507 ! fucose metabolic process GO:0006004 26 18 0,000 0,02443662 0,03878828 ! response to fungus GO:0009620 19 18 0,000 0,02443662 0,03876153 ! peptide cross-linking GO:0018149 31 18 0,000 0,02443662 0,03873482 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02443662 0,03870814 ! heart process GO:0003015 27 18 0,000 0,02443662 0,0386815 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02443662 0,0386549 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02443662 0,03862833 ! somitogenesis GO:0001756 24 18 0,000 0,02443662 0,0386018 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02443662 0,03857531 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02443662 0,03854885 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02443662 0,03852243 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02443662 0,03849604 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02443662 0,0384697 ! vitamin transport GO:0051180 24 18 0,000 0,02443662 0,03844338 ! hormone transport GO:0009914 27 18 0,000 0,02443662 0,03841711 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02443662 0,03839086 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02443662 0,03836466 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02443662 0,03833849 ! cell-cell recognition GO:0009988 20 18 0,000 0,02443662 0,03831235 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02443662 0,03828626 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02443662 0,03826019 ! regulation of glucose import GO:0046324 21 18 0,000 0,02443662 0,03823417 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02443662 0,03820817 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02443662 0,03818222 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02443662 0,0381563 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02443662 0,03813041 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,02577729 0,0401951 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,02577729 0,04016787 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,02577729 0,04014067 ! positive regulation of ossification GO:0045778 30 19 0,000 0,02577729 0,04011351 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,02577729 0,04008639 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,02577729 0,04005931 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,02577729 0,04003226 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,02577729 0,04000525 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,02577729 0,03997827 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,02577729 0,03995133 ! regeneration GO:0031099 32 19 0,000 0,02577729 0,03992443 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,02577729 0,03989756 ! response to alkaloid GO:0043279 32 19 0,000 0,02577729 0,03987073 ! sensory perception of taste GO:0050909 23 19 0,000 0,02577729 0,03984393 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,02577729 0,03981718 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,02577729 0,03979045 ! smooth muscle contraction GO:0006939 36 19 0,000 0,02577729 0,03976377 ! peroxisome organization GO:0007031 29 19 0,000 0,02577729 0,03973711 ! digestive system process GO:0022600 30 19 0,000 0,02577729 0,0397105 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,02577729 0,03968392 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,02577729 0,03965737 ! response to vitamin A GO:0033189 26 19 0,000 0,02577729 0,03963086 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,02577729 0,03960439 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,02577729 0,03957795 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,02577729 0,03955155 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,02577729 0,03952518 ! response to starvation GO:0042594 30 19 0,000 0,02577729 0,03949885 ! sex determination GO:0007530 29 19 0,000 0,02577729 0,03947255 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,02577729 0,03944629 ! plasma membrane fusion GO:0045026 23 19 0,000 0,02577729 0,03942006 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,02577729 0,03939387 ! cytolysis GO:0019835 20 19 0,000 0,02577729 0,03936771 ! renal system process GO:0003014 35 19 0,000 0,02577729 0,03934159 ! vasodilation GO:0042311 33 19 0,000 0,02577729 0,0393155 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,02577729 0,03928945 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,02577729 0,03926343 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,02577729 0,03923744 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,02577729 0,03921149 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,02577729 0,03918557 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,02577729 0,03915969 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,02577729 0,03913384 ! sarcomere organization GO:0045214 23 19 0,000 0,02577729 0,03910803 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,02577729 0,03908225 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,02577729 0,0390565 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,02577729 0,03903079 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,02577729 0,03900511 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,02577729 0,03897947 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,02577729 0,03895386 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,02577729 0,03892828 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,02577729 0,03890274 ! protein stabilization GO:0050821 26 19 0,000 0,02577729 0,03887723 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,0271162 0,04086977 ! iron ion transport GO:0006826 37 20 0,000 0,0271162 0,040843 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,0271162 0,04081627 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,0271162 0,04078958 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,0271162 0,04076292 ! response to vitamin GO:0033273 29 20 0,000 0,0271162 0,04073629 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,0271162 0,0407097 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,0271162 0,04068315 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,0271162 0,04065662 ! spinal cord development GO:0021510 31 20 0,000 0,0271162 0,04063014 ! response to ethanol GO:0045471 37 20 0,000 0,0271162 0,04060369 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,0271162 0,04057727 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,0271162 0,04055089 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,0271162 0,04052454 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,0271162 0,04049822 ! chromosome condensation GO:0030261 31 20 0,000 0,0271162 0,04047194 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,0271162 0,04044569 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,0271162 0,04041948 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,0271162 0,0403933 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,0271162 0,04036716 ! pallium development GO:0021543 38 20 0,000 0,0271162 0,04034105 ! DNA modification GO:0006304 28 20 0,000 0,0271162 0,04031497 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,0271162 0,04028893 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,0271162 0,04026292 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,0271162 0,04023694 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,0271162 0,040211 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,0271162 0,04018509 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,0271162 0,04015922 ! collagen catabolic process GO:0030574 25 20 0,000 0,0271162 0,04013337 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,0271162 0,04010756 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,0271162 0,04008179 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,0271162 0,04005604 ! alditol metabolic process GO:0019400 24 20 0,000 0,0271162 0,04003033 ! actin filament-based movement GO:0030048 34 20 0,000 0,0271162 0,04000466 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,02845334 0,04195044 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,02845334 0,04192357 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,02845334 0,04189673 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02845334 0,04186993 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02845334 0,04184315 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,02845334 0,04181642 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,02845334 0,04178971 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,02845334 0,04176305 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,02845334 0,04173641 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,02845334 0,04170981 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,02845334 0,04168324 ! protein amino acid acylation GO:0043543 37 21 0,000 0,02845334 0,04165671 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,02845334 0,04163021 ! vesicle docking GO:0048278 27 21 0,000 0,02845334 0,04160375 ! phototransduction GO:0007602 25 21 0,000 0,02845334 0,04157731 ! dendrite development GO:0016358 35 21 0,000 0,02845334 0,04155092 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,02845334 0,04152455 ! ovarian follicle development GO:0001541 30 21 0,000 0,02845334 0,04149822 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,02845334 0,04147192 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,02845334 0,04144566 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,02845334 0,04141943 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,02845334 0,04139323 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,02845334 0,04136706 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,02845334 0,04134093 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,02845334 0,04131483 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,02845334 0,04128877 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,02845334 0,04126273 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,02845334 0,04123673 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,02845334 0,04121076 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,02845334 0,04118483 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,02845334 0,04115893 ! fatty acid transport GO:0015908 30 21 0,000 0,02845334 0,04113306 ! immunoglobulin production GO:0002377 33 21 0,000 0,02845334 0,04110722 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,02845334 0,04108141 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,02845334 0,04105564 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,02845334 0,0410299 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,02845334 0,04100419 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,02845334 0,04097852 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,02845334 0,04095287 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02845334 0,04092726 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,02845334 0,04090168 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,02845334 0,04087614 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,02845334 0,04085062 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,02845334 0,04082514 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,02845334 0,04079968 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02845334 0,04077426 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,02978873 0,04266132 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,02978873 0,04263477 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,02978873 0,04260825 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,02978873 0,04258177 ! viral genome replication GO:0019079 29 22 0,000 0,02978873 0,04255533 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,02978873 0,04252891 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,02978873 0,04250253 ! leukocyte adhesion GO:0007159 38 22 0,000 0,02978873 0,04247618 ! molting cycle process GO:0022404 40 22 0,000 0,02978873 0,04244986 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,02978873 0,04242357 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,02978873 0,04239732 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,02978873 0,0423711 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,02978873 0,04234492 ! vasculogenesis GO:0001570 33 22 0,000 0,02978873 0,04231876 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,02978873 0,04229264 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,02978873 0,04226655 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,02978873 0,04224049 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,02978873 0,04221446 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,02978873 0,04218847 ! lysosome organization GO:0007040 37 22 0,000 0,02978873 0,04216251 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,02978873 0,04213658 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,02978873 0,04211068 ! regulation of behavior GO:0050795 38 22 0,000 0,02978873 0,04208481 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,02978873 0,04205898 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,02978873 0,04203317 ! membrane depolarization GO:0051899 35 22 0,000 0,02978873 0,0420074 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,02978873 0,04198166 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,02978873 0,04195595 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,02978873 0,04193028 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,02978873 0,04190463 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,02978873 0,04187902 ! blastocyst development GO:0001824 37 22 0,000 0,02978873 0,04185344 ! neural tube closure GO:0001843 33 22 0,000 0,02978873 0,04182788 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! protein tetramerization GO:0051262 39 22 0,000 0,02978873 0,04180236 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03112235 0,0436472 ! neuron fate commitment GO:0048663 32 23 0,000 0,03112235 0,0436206 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03112235 0,04359404 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,03112235 0,0435675 ! myelination GO:0042552 35 23 0,000 0,03112235 0,043541 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03112235 0,04351453 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,03112235 0,0434881 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,03112235 0,04346169 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,03112235 0,04343532 ! vesicle targeting GO:0006903 32 23 0,000 0,03112235 0,04340898 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03112235 0,04338267 ! osteoblast differentiation GO:0001649 40 23 0,000 0,03112235 0,04335639 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,03112235 0,04333015 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03112235 0,04330394 ! interaction with host GO:0051701 37 23 0,000 0,03112235 0,04327776 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03112235 0,04325161 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03112235 0,04322549 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,03112235 0,0431994 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03112235 0,04317335 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,03112235 0,04314732 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03112235 0,04312133 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03112235 0,04309537 ! cell fate determination GO:0001709 45 23 0,000 0,03112235 0,04306944 ! pentose metabolic process GO:0019321 31 23 0,000 0,03112235 0,04304354 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03112235 0,04301767 ! spermatid development GO:0007286 33 23 0,000 0,03112235 0,04299184 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03112235 0,04296603 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03112235 0,04294026 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03112235 0,04291451 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,03112235 0,0428888 ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03112235 0,04286312 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,03112235 0,04283747 ! regulation of amine transport GO:0051952 38 23 0,000 0,03112235 0,04281185 ! liver development GO:0001889 40 23 0,000 0,03112235 0,04278626 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,03245422 0,04459062 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,03245422 0,044564 ! initiation of viral infection GO:0019059 42 24 0,000 0,03245422 0,04453741 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,03245422 0,04451085 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,03245422 0,04448433 ! superoxide metabolic process GO:0006801 32 24 0,000 0,03245422 0,04445783 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,03245422 0,04443137 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,03245422 0,04440494 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,03245422 0,04437854 ! sperm motility GO:0030317 27 24 0,000 0,03245422 0,04435217 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,03245422 0,04432583 ! vacuole organization GO:0007033 39 24 0,000 0,03245422 0,04429953 ! receptor metabolic process GO:0043112 37 24 0,000 0,03245422 0,04427325 ! neural crest cell development GO:0014032 39 24 0,000 0,03245422 0,04424701 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,03245422 0,04422079 ! primary neural tube formation GO:0014020 35 24 0,000 0,03245422 0,04419461 ! negative regulation of cell development GO:0010721 56 24 0,000 0,03245422 0,04416846 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,03245422 0,04414234 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,03245422 0,04411625 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,03245422 0,0440902 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,03245422 0,04406417 ! glutathione metabolic process GO:0006749 29 24 0,000 0,03245422 0,04403817 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,03245422 0,04401221 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,03245422 0,04398627 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,03378433 0,04576205 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03378433 0,04573511 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,03378433 0,04570821 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,03378433 0,04568134 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,03378433 0,0456545 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,03378433 0,04562769 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,03378433 0,04560092 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,03378433 0,04557417 ! peptide transport GO:0015833 43 25 0,000 0,03378433 0,04554746 ! male gonad development GO:0008584 33 25 0,000 0,03378433 0,04552077 ! iron ion homeostasis GO:0055072 39 25 0,000 0,03378433 0,04549412 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,03378433 0,0454675 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03378433 0,04544091 ! phospholipid transport GO:0015914 35 25 0,000 0,03378433 0,04541435 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,03378433 0,04538783 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,03378433 0,04536133 ! detection of light stimulus GO:0009583 30 25 0,000 0,03378433 0,04533487 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,03378433 0,04530843 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,03378433 0,04528203 ! leukocyte proliferation GO:0070661 39 25 0,000 0,03378433 0,04525566 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,03378433 0,04522931 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,03511269 0,04698033 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,03511269 0,04695302 ! translational initiation GO:0006413 43 26 0,000 0,03511269 0,04692573 ! regulation of pH GO:0006885 36 26 0,000 0,03511269 0,04689848 ! circadian rhythm GO:0007623 42 26 0,000 0,03511269 0,04687126 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,03511269 0,04684408 ! post-embryonic development GO:0009791 42 26 0,000 0,03511269 0,04681692 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,03511269 0,0467898 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,03511269 0,0467627 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,03511269 0,04673564 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,03511269 0,04670861 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,03511269 0,04668161 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,03511269 0,04665464 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,03511269 0,04662771 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,03511269 0,0466008 ! regulation of coagulation GO:0050818 39 26 0,000 0,03511269 0,04657393 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,0364393 0,0483057 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,0364393 0,04827787 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,0364393 0,04825008 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,0364393 0,04822232 ! membrane docking GO:0022406 39 27 0,000 0,0364393 0,04819459 ! catechol metabolic process GO:0009712 43 27 0,000 0,0364393 0,04816689 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,0364393 0,04813922 ! acute-phase response GO:0006953 42 27 0,000 0,0364393 0,04811159 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,0364393 0,04808399 ! myofibril assembly GO:0030239 36 27 0,000 0,0364393 0,04805642 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,0364393 0,04802888 ! response to ionizing radiation GO:0010212 47 27 0,000 0,0364393 0,04800137 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,0364393 0,04797389 ! natural killer cell activation GO:0030101 35 27 0,000 0,0364393 0,04794645 ! lipid oxidation GO:0034440 38 27 0,000 0,0364393 0,04791903 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,0364393 0,04789165 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,0364393 0,0478643 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,0364393 0,04783698 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,0364393 0,04780969 GO:0043433|negative regulation of transcription factor activity, ! gene silencing GO:0016458 41 27 0,000 0,0364393 0,04778243 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,03776416 0,04949149 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,03776416 0,04946331 ! phenol metabolic process GO:0018958 44 28 0,000 0,03776416 0,04943516 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,03776416 0,04940704 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,03776416 0,04937895 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,03776416 0,04935089 ! cell junction assembly GO:0034329 56 28 0,000 0,03776416 0,04932287 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,03776416 0,04929488 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,03776416 0,04926691 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,03776416 0,04923899 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,03776416 0,04921109 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,03776416 0,04918322 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,03776416 0,04915539 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,03776416 0,04912759 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,03776416 0,04909981 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,03776416 0,04907207 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,03776416 0,04904437 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,03776416 0,04901669 ! mesoderm formation GO:0001707 46 28 0,000 0,03776416 0,04898904 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,03776416 0,04896143 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,03776416 0,04893384 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,03776416 0,04890629 ! ensheathment of neurons GO:0007272 43 28 0,000 0,03776416 0,04887877 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,03776416 0,04885128 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,03776416 0,04882382 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,03776416 0,04879639 ! neural tube formation GO:0001841 41 28 0,000 0,03776416 0,04876899 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,03776416 0,04874162 ! placenta development GO:0001890 37 28 0,000 0,03776416 0,04871429 ! regulation of B cell activation GO:0050864 42 28 0,000 0,03776416 0,04868698 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,03908728 0,05036456 ! regulation of innate immune response GO:0045088 38 29 0,000 0,03908728 0,05033636 ! ovulation cycle process GO:0022602 41 29 0,000 0,03908728 0,05030819 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,03908728 0,05028005 ! protein targeting to membrane GO:0006612 53 29 0,000 0,03908728 0,05025195 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,03908728 0,05022388 ! mismatch repair GO:0006298 34 29 0,000 0,03908728 0,05019583 ! muscle cell development GO:0055001 38 29 0,000 0,03908728 0,05016782 ! formation of primary germ layer GO:0001704 48 29 0,000 0,03908728 0,05013984 ! telencephalon development GO:0021537 52 29 0,000 0,03908728 0,05011189 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,03908728 0,05008398 ! eye morphogenesis GO:0048592 51 29 0,000 0,03908728 0,05005609 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,03908728 0,05002823 ! tissue homeostasis GO:0001894 42 29 0,000 0,03908728 0,05000041 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,04040865 0,05166197 ! collagen metabolic process GO:0032963 40 30 0,000 0,04040865 0,05163327 ! organic anion transport GO:0015711 51 30 0,000 0,04040865 0,0516046 ! cholesterol transport GO:0030301 46 30 0,000 0,04040865 0,05157597 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,04040865 0,05154736 ! spindle organization GO:0007051 37 30 0,000 0,04040865 0,05151879 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,04040865 0,05149024 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,04040865 0,05146173 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,04040865 0,05143326 ! ceramide metabolic process GO:0006672 43 30 0,000 0,04040865 0,05140481 ! ovulation cycle GO:0042698 43 30 0,000 0,04040865 0,05137639 ! hindbrain development GO:0030902 45 30 0,000 0,04040865 0,05134801 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,04040865 0,05131965 ! adult locomotory behavior GO:0008344 47 30 0,000 0,04040865 0,05129133 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,04040865 0,05126304 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,04040865 0,05123478 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,04040865 0,05120655 ! response to heat GO:0009408 41 30 0,000 0,04040865 0,05117835 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,04040865 0,05115019 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,04040865 0,05112205 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,04172828 0,05276253 ! negative regulation of secretion GO:0051048 49 31 0,000 0,04172828 0,05273354 ! mammary gland development GO:0030879 57 31 0,000 0,04172828 0,05270458 ! glial cell differentiation GO:0010001 55 31 0,000 0,04172828 0,05267565 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,04172828 0,05264676 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,04172828 0,0526179 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,04172828 0,05258906 ! odontogenesis GO:0042476 50 31 0,000 0,04172828 0,05256026 ! segmentation GO:0035282 41 31 0,000 0,04172828 0,0525315 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,04172828 0,05250276 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,04172828 0,05247405 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,04172828 0,05244538 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,04172828 0,05241674 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,04172828 0,05238812 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,04172828 0,05235954 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,04172828 0,05233099 ! RNA modification GO:0009451 40 31 0,000 0,04172828 0,05230248 ! regulation of muscle development GO:0048634 48 32 0,000 0,04304617 0,05392494 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,04304617 0,05389559 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,04304617 0,05386626 ! meiosis I GO:0007127 52 32 0,000 0,04304617 0,05383697 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,04304617 0,05380771 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,04304617 0,05377849 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,04304617 0,05374929 ! peripheral nervous system development GO:0007422 53 32 0,000 0,04304617 0,05372013 ! regulation of protein stability GO:0031647 48 32 0,000 0,04304617 0,05369099 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,04304617 0,05366189 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,04304617 0,05363282 ! cytokine production GO:0001816 44 32 0,000 0,04304617 0,05360379 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,04304617 0,05357478 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,04304617 0,0535458 ! vesicle localization GO:0051648 47 32 0,000 0,04304617 0,05351686 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,04436232 0,05512336 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,04436232 0,0550936 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,04436232 0,05506387 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,04436232 0,05503417 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,04436232 0,0550045 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,04436232 0,05497486 ! sister chromatid segregation GO:0000819 46 33 0,000 0,04436232 0,05494526 ! actomyosin structure organization GO:0031032 43 33 0,000 0,04436232 0,05491569 ! cell junction organization GO:0034330 63 33 0,000 0,04436232 0,05488615 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,04436232 0,05485664 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,04436232 0,05482716 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,04436232 0,05479772 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,04436232 0,0547683 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,04436232 0,05473892 ! female gonad development GO:0008585 49 33 0,000 0,04436232 0,05470957 ! positive regulation of cell development GO:0010720 54 33 0,000 0,04436232 0,05468025 ! lipid homeostasis GO:0055088 55 33 0,000 0,04436232 0,05465096 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,04436232 0,05462171 ! regulation of proteolysis GO:0030162 50 33 0,000 0,04436232 0,05459248 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,04436232 0,05456329 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,04436232 0,05453412 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,04436232 0,05450499 ! cytokinesis GO:0000910 52 33 0,000 0,04436232 0,05447589 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,04436232 0,05444682 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,04567674 0,05603014 ! mRNA catabolic process GO:0006402 48 34 0,000 0,04567674 0,05600027 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,04567674 0,05597044 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,04567674 0,05594063 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,04567674 0,05591086 ! feeding behavior GO:0007631 45 34 0,000 0,04567674 0,05588112 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,04567674 0,05585142 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,04567674 0,05582174 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,04567674 0,05579209 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,04567674 0,05576248 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,04567674 0,0557329 ! neuron migration GO:0001764 46 34 0,000 0,04567674 0,05570335 ! female gamete generation GO:0007292 43 34 0,000 0,04567674 0,05567383 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,04567674 0,05564434 ! polyol metabolic process GO:0019751 44 34 0,000 0,04567674 0,05561488 ! aerobic respiration GO:0009060 47 34 0,000 0,04567674 0,05558546 ! embryonic organ development GO:0048568 45 34 0,000 0,04567674 0,05555606 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,04567674 0,0555267 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,04698943 0,05709228 ! Notch signaling pathway GO:0007219 56 35 0,000 0,04698943 0,05706214 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,04698943 0,05703203 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,04698943 0,05700195 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,04698943 0,0569719 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,04698943 0,05694188 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,04698943 0,0569119 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,04698943 0,05688194 ! glycogen metabolic process GO:0005977 48 35 0,000 0,04698943 0,05685202 ! pigment metabolic process GO:0042440 61 35 0,000 0,04698943 0,05682213 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,04698943 0,05679227 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,04698943 0,05676244 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,04830039 0,05831543 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,04830039 0,05828483 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,04830039 0,05825427 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,04830039 0,05822374 ! organic ether metabolic process GO:0018904 46 36 0,000 0,04830039 0,05819324 ! tissue remodeling GO:0048771 62 36 0,000 0,04830039 0,05816277 ! neural tube development GO:0021915 50 36 0,000 0,04830039 0,05813233 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,04830039 0,05810193 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,04830039 0,05807156 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,04830039 0,05804122 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,04830039 0,05801091 ! glucan metabolic process GO:0044042 49 36 0,000 0,04830039 0,05798063 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,04960962 0,05952119 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,04960962 0,05949015 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,04960962 0,05945915 ! ion transmembrane transport GO:0034220 56 37 0,000 0,04960962 0,05942818 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,04960962 0,05939725 ! regulation of protein secretion GO:0050708 51 37 0,000 0,04960962 0,05936634 ! amino acid activation GO:0043038 52 37 0,000 0,04960962 0,05933547 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,04960962 0,05930463 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,05091712 0,06083604 ! gliogenesis GO:0042063 71 38 0,000 0,05091712 0,06080445 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,05091712 0,0607729 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,05091712 0,06074137 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,05091712 0,06070989 ! phagocytosis GO:0006909 60 38 0,000 0,05091712 0,06067843 ! mesenchymal cell development GO:0014031 64 38 0,000 0,05091712 0,06064701 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,05091712 0,06061562 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,05222289 0,06213795 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,05222289 0,06210582 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,05222289 0,06207373 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,05222289 0,06204166 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,05222289 0,06200963 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,05222289 0,06197764 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,05222289 0,06194567 ! male sex differentiation GO:0046661 53 39 0,000 0,05222289 0,06191374 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,05222289 0,06188184 ! chromatin remodeling GO:0006338 68 39 0,000 0,05222289 0,06184998 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,05222289 0,06181815 ! developmental growth GO:0048589 62 39 0,000 0,05222289 0,06178635 ! cell growth GO:0016049 61 39 0,000 0,05222289 0,06175458 ! synapse organization GO:0050808 55 39 0,000 0,05222289 0,06172285 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,05352695 0,06323163 ! regulation of tube size GO:0035150 60 40 0,000 0,05352695 0,06319917 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,05352695 0,06316675 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,05352695 0,06313435 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,05352695 0,06310199 ! peptide metabolic process GO:0006518 56 40 0,000 0,05352695 0,06306967 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,05352695 0,06303737 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,05352695 0,06300511 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,05352695 0,06297288 ! B cell differentiation GO:0030183 62 40 0,000 0,05352695 0,06294069 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,05352695 0,06290853 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,05352695 0,0628764 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,05352695 0,0628443 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,05482929 0,06434049 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,05482929 0,06430768 ! glucose transport GO:0015758 52 41 0,000 0,05482929 0,0642749 ! endosome transport GO:0016197 71 41 0,000 0,05482929 0,06424216 ! striated muscle contraction GO:0006941 62 41 0,000 0,05482929 0,06420945 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,05482929 0,06417677 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,05482929 0,06414413 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,05482929 0,06411152 ! biopolymer methylation GO:0043414 62 41 0,000 0,05482929 0,06407894 ! mitochondrial transport GO:0006839 60 42 0,000 0,05612991 0,06556566 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,05612991 0,06553238 ! cellular component disassembly GO:0022411 64 42 0,000 0,05612991 0,06549913 ! hexose transport GO:0008645 54 42 0,000 0,05612991 0,06546592 GO:0015749|monosaccharide transport, ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,05612991 0,06543273 ! excretion GO:0007588 63 42 0,000 0,05612991 0,06539959 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,05612991 0,06536647 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,05612991 0,06533339 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,05612991 0,06530035 ! regulation of cell shape GO:0008360 78 42 0,000 0,05612991 0,06526733 ! positive regulation of binding GO:0051099 59 43 0,000 0,05742881 0,06674394 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,05742881 0,06671023 ! leukocyte migration GO:0050900 60 43 0,000 0,05742881 0,06667656 ! neuromuscular process GO:0050905 79 43 0,000 0,05742881 0,06664292 ! activation of caspase activity GO:0006919 65 43 0,000 0,05742881 0,06660931 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,05742881 0,06657574 ! tRNA processing GO:0008033 49 43 0,000 0,05742881 0,0665422 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,05742881 0,06650869 ! vesicle organization GO:0016050 79 43 0,000 0,05742881 0,06647522 ! methylation GO:0032259 64 43 0,000 0,05742881 0,06644178 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,058726 0,0679084 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,058726 0,06787427 ! glycolysis GO:0006096 53 44 0,000 0,058726 0,06784018 ! regulation of action potential GO:0001508 71 44 0,000 0,058726 0,06780613 ! regulation of ion transport GO:0043269 57 44 0,000 0,058726 0,0677721 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,058726 0,06773812 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,058726 0,06770416 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,058726 0,06767024 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,058726 0,06763636 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,058726 0,0676025 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,058726 0,06756869 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,058726 0,0675349 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,058726 0,06750115 ! RNA catabolic process GO:0006401 64 45 0,000 0,06002148 0,06895575 ! positive regulation of defense response GO:0031349 59 45 0,000 0,06002148 0,06892132 ! regulation of translational initiation GO:0006446 64 45 0,000 0,06002148 0,06888693 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,06002148 0,06885257 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,06002148 0,06881825 ! cell recognition GO:0008037 58 45 0,000 0,06002148 0,06878396 ! cell maturation GO:0048469 60 45 0,000 0,06002148 0,0687497 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,06002148 0,06871548 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,06131525 0,07016173 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,06131525 0,07012684 ! cell redox homeostasis GO:0045454 63 46 0,000 0,06131525 0,07009199 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,06131525 0,07005717 ! regulation of ossification GO:0030278 71 46 0,000 0,06131525 0,07002238 ! histone modification GO:0016570 68 46 0,000 0,06131525 0,06998763 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,06131525 0,06995292 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,06260732 0,07139159 ! viral infectious cycle GO:0019058 71 47 0,000 0,06260732 0,07135621 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,06260732 0,07132087 ! covalent chromatin modification GO:0016569 75 47 0,000 0,06260732 0,07128556 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,06260732 0,07125029 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,06260732 0,07121505 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,06260732 0,07117985 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,06260732 0,07114468 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,06260732 0,07110954 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 0,000 0,06260732 0,07107445 ! chloride transport GO:0006821 67 48 0,000 0,06389768 0,07250353 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,06389768 0,07246778 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,06389768 0,07243206 ! response to temperature stimulus GO:0009266 62 48 0,000 0,06389768 0,07239638 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,06389768 0,07236074 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,06389768 0,07232513 ! gastrulation GO:0007369 73 48 0,000 0,06389768 0,07228955 ! heart morphogenesis GO:0003007 65 48 0,000 0,06389768 0,07225401 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,06389768 0,0722185 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,06389768 0,07218303 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,06389768 0,0721476 ! regulation of endocytosis GO:0030100 63 48 0,000 0,06389768 0,0721122 ! nuclear export GO:0051168 69 48 0,000 0,06389768 0,07207683 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,06389768 0,0720415 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,06389768 0,0720062 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,06518633 0,07342241 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,06518633 0,07338647 ! sensory perception of smell GO:0007608 61 49 0,000 0,06518633 0,07335057 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,06518633 0,0733147 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,06518633 0,07327887 ! RNA elongation GO:0006354 62 49 0,000 0,06518633 0,07324307 ! germ cell development GO:0007281 68 49 0,000 0,06518633 0,07320731 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,06518633 0,07317158 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,06518633 0,07313589 ! cartilage development GO:0051216 70 49 0,000 0,06518633 0,07310023 ! regulation of actin filament length GO:0030832 72 50 0,000 0,06647329 0,0745071 ! membrane fusion GO:0006944 80 50 0,000 0,06647329 0,07447081 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,06647329 0,07443455 ! lipid modification GO:0030258 73 50 0,000 0,06647329 0,07439833 ! positive regulation of growth GO:0045927 67 50 0,000 0,06647329 0,07436214 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,06647329 0,07432599 ! proton transport GO:0015992 75 50 0,000 0,06647329 0,07428988 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,06647329 0,0742538 ! positive regulation of secretion GO:0051047 71 51 0,000 0,06775855 0,07565275 ! hydrogen transport GO:0006818 77 51 0,000 0,06775855 0,07561604 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,06775855 0,07557937 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell migration GO:0030335 92 51 0,000 0,06775855 0,07554274 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,06775855 0,07550614 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,06775855 0,07546957 ! adult behavior GO:0030534 80 51 0,000 0,06775855 0,07543304 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,06775855 0,07539655 ! transition metal ion transport GO:0000041 74 52 0,000 0,06904211 0,07678765 ! regulation of cellular component size GO:0032535 74 52 0,000 0,06904211 0,07675054 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,06904211 0,07671346 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,06904211 0,07667642 ! establishment of organelle localization GO:0051656 85 52 0,000 0,06904211 0,07663941 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,07032398 0,07802468 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,07032398 0,07798706 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,07032398 0,07794948 ! single fertilization GO:0007338 59 53 0,000 0,07032398 0,07791193 ! cell projection assembly GO:0030031 76 53 0,000 0,07032398 0,07787442 ! amino acid transport GO:0006865 84 54 0,000 0,07160416 0,07925388 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,07160416 0,07921576 ! regulation of mitosis GO:0007088 84 54 0,000 0,07160416 0,07917768 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,07160416 0,07913963 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,07160416 0,07910162 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,07160416 0,07906364 ! DNA catabolic process GO:0006308 67 54 0,000 0,07160416 0,07902571 ! detection of external stimulus GO:0009581 66 54 0,000 0,07160416 0,0789878 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,07160416 0,07894994 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,07160416 0,07891211 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,07160416 0,07887432 ! exocytosis GO:0006887 74 55 0,000 0,07288265 0,08024418 ! mesoderm development GO:0007498 76 55 0,000 0,07288265 0,08020579 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,07288265 0,08016743 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,07288265 0,08012911 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,07415945 0,0814939 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,07415945 0,08145498 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,07415945 0,0814161 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,07415945 0,08137726 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,07543457 0,08273701 ! carbohydrate transport GO:0008643 74 57 0,000 0,07543457 0,08269757 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,07543457 0,08265817 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,07543457 0,08261881 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,07543457 0,08257949 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,07543457 0,0825402 ! camera-type eye development GO:0043010 88 57 0,000 0,07543457 0,08250095 ! secondary metabolic process GO:0019748 84 57 0,000 0,07543457 0,08246174 ! developmental maturation GO:0021700 75 57 0,000 0,07543457 0,08242257 ! gonad development GO:0008406 79 57 0,000 0,07543457 0,08238343 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,076708 0,08373441 ! viral reproductive process GO:0022415 87 58 0,000 0,076708 0,08369469 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,076708 0,083655 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,076708 0,08361536 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,076708 0,08357575 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,07797975 0,08492113 ! lung development GO:0030324 94 59 0,000 0,07797975 0,08488094 ! actin filament organization GO:0007015 95 59 0,000 0,07797975 0,08484079 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,07797975 0,08480068 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,07797975 0,0847606 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,07924983 0,08610042 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,07924983 0,08605977 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,07924983 0,08601916 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,07924983 0,08597858 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,07924983 0,08593805 ! regulation of heart contraction GO:0008016 91 60 0,000 0,07924983 0,08589755 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,07924983 0,08585709 ! fertilization GO:0009566 68 60 0,000 0,07924983 0,08581667 ! meiosis GO:0007126 96 61 0,000 0,08051822 0,08714913 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,08051822 0,08710814 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,08051822 0,08706719 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,08051822 0,08702627 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,08051822 0,0869854 ! extracellular matrix organization GO:0030198 103 61 0,000 0,08051822 0,08694456 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,08051822 0,08690376 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,08051822 0,086863 ! amine catabolic process GO:0009310 90 62 0,000 0,08178494 0,08818817 ! neurotransmitter transport GO:0006836 81 62 0,000 0,08178494 0,08814685 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,08178494 0,08810556 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,08178494 0,08806431 ! respiratory tube development GO:0030323 99 62 0,000 0,08178494 0,0880231 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,08178494 0,08798193 ! meiotic cell cycle GO:0051321 97 62 0,000 0,08178494 0,0879408 ! organelle localization GO:0051640 96 62 0,000 0,08178494 0,08789971 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,08304999 0,08921765 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,08304999 0,089176 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,08304999 0,08913438 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,08304999 0,08909281 ! viral reproduction GO:0016032 92 63 0,000 0,08304999 0,08905128 ! regulation of lipase activity GO:0060191 109 63 0,000 0,08304999 0,08900978 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,08431337 0,09032173 ! negative regulation of cell size GO:0045792 108 64 0,000 0,08431337 0,09027968 ! appendage morphogenesis GO:0035107 93 64 0,000 0,08431337 0,09023767 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,08431337 0,0901957 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,08431337 0,09015377 ! hexose catabolic process GO:0019320 82 64 0,000 0,08431337 0,09011188 ! respiratory system development GO:0060541 100 64 0,000 0,08431337 0,09007002 ! adaptive immune response GO:0002250 94 64 0,000 0,08431337 0,09002821 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,08557508 0,09133304 ! regulation of caspase activity GO:0043281 97 65 0,000 0,08557508 0,09129067 ! appendage development GO:0048736 94 65 0,000 0,08557508 0,09124835 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,08557508 0,09120607 ! defense response to bacterium GO:0042742 73 65 0,000 0,08557508 0,09116382 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,08557508 0,09112162 ! activation of immune response GO:0002253 83 65 0,000 0,08557508 0,09107945 ! protein oligomerization GO:0051259 100 65 0,000 0,08557508 0,09103732 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,08683513 0,09233509 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,08683513 0,09229242 ! antigen processing and presentation GO:0019882 96 66 0,000 0,08683513 0,09224979 ! axon guidance GO:0007411 99 66 0,000 0,08683513 0,0922072 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,08683513 0,09216465 ! regulation of immune effector process GO:0002697 101 66 0,000 0,08683513 0,09212214 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,08809351 0,09341405 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,08809351 0,093371 ! acute inflammatory response GO:0002526 92 68 0,000 0,08935023 0,09465938 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,08935023 0,0946158 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,08935023 0,09457226 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,08935023 0,09452876 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,08935023 0,0944853 ! rhythmic process GO:0048511 105 68 0,000 0,08935023 0,09444188 ! inorganic anion transport GO:0015698 93 68 0,000 0,08935023 0,0943985 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,09060529 0,09568051 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,09060529 0,0956366 ! response to drug GO:0042493 108 69 0,000 0,09060529 0,09559273 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,09185869 0,09687069 ! humoral immune response GO:0006959 86 70 0,000 0,09185869 0,0968263 ! eye development GO:0001654 111 70 0,000 0,09185869 0,09678194 ! amine transport GO:0015837 101 70 0,000 0,09185869 0,09673763 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,09185869 0,09669336 ! regulation of catabolic process GO:0009894 106 70 0,000 0,09185869 0,09664912 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,09311043 0,09792135 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,09311043 0,0978766 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,09311043 0,09783188 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,09311043 0,09778721 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,09436052 0,09905486 ! response to hypoxia GO:0001666 132 72 0,000 0,09436052 0,09900967 ! regulation of blood pressure GO:0008217 107 73 0,000 0,09560897 0,10027388 ! mitochondrion organization GO:0007005 104 73 0,000 0,09560897 0,10022818 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,09560897 0,10018251 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,09685576 0,10144273 ! response to oxygen levels GO:0070482 137 74 0,000 0,09685576 0,10139656 ! digestion GO:0007586 97 74 0,000 0,09685576 0,10135043 ! protein import into nucleus GO:0006606 118 74 0,000 0,09685576 0,10130434 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,09685576 0,10125829 ! blood coagulation GO:0007596 116 75 0,000 0,0981009 0,10251343 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,0981009 0,10246688 ! response to nutrient GO:0007584 104 75 0,000 0,0981009 0,10242037 ! nuclear import GO:0051170 121 75 0,000 0,0981009 0,1023739 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,0981009 0,10232747 ! amine biosynthetic process GO:0009309 97 76 0,000 0,0993444 0,10357757 ! tRNA metabolic process GO:0006399 95 76 0,000 0,0993444 0,10353064 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,0993444 0,10348375 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,10058625 0,10472992 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,10058625 0,10468253 ! sex differentiation GO:0007548 105 77 0,000 0,10058625 0,10463518 ! protein ubiquitination GO:0016567 125 77 0,000 0,10058625 0,10458788 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,10058625 0,10454062 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,10058625 0,1044934 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,10182647 0,10573403 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,10182647 0,10568632 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,10306504 0,10692359 ! cellular respiration GO:0045333 107 79 0,000 0,10306504 0,10687538 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,10306504 0,10682722 ! T cell activation GO:0042110 134 79 0,000 0,10306504 0,1067791 ! regulation of lyase activity GO:0051339 133 79 0,000 0,10306504 0,10673102 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,10306504 0,10668299 ! chromatin assembly GO:0031497 102 80 0,000 0,10430198 0,10791478 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,10430198 0,10786626 ! protein localization in nucleus GO:0034504 133 80 0,000 0,10430198 0,10781778 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,10430198 0,10776934 ! forebrain development GO:0030900 131 80 0,000 0,10430198 0,10772095 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,10553729 0,10894783 ! hemostasis GO:0007599 125 81 0,000 0,10553729 0,10889895 ! mRNA transport GO:0051028 121 81 0,000 0,10553729 0,10885012 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,10553729 0,10880133 ! vitamin metabolic process GO:0006766 103 81 0,000 0,10553729 0,10875258 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,10553729 0,10870388 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,10677096 0,10992534 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,10677096 0,10987615 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,108003 0,11109432 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,108003 0,11104465 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,108003 0,11099504 ! regulation of defense response GO:0031347 117 84 0,000 0,10923341 0,1122094 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,10923341 0,1121593 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,10923341 0,11210925 ! sterol metabolic process GO:0016125 120 84 0,000 0,10923341 0,11205925 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,11046219 0,1132693 ! rRNA metabolic process GO:0016072 107 85 0,000 0,11046219 0,11321882 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,11046219 0,11316839 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,11046219 0,11311801 ! regulation of membrane potential GO:0042391 128 85 0,000 0,11046219 0,11306766 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,11046219 0,11301737 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,11168935 0,1142221 ! cell cycle arrest GO:0007050 150 86 0,000 0,11168935 0,11417134 ! nucleosome organization GO:0034728 114 87 0,000 0,11291489 0,11537283 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,11291489 0,1153216 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,11291489 0,11527042 ! female pregnancy GO:0007565 130 87 0,000 0,11291489 0,11521928 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,11291489 0,11516818 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,11413881 0,11636492 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,11413881 0,11631336 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,11413881 0,11626185 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,11413881 0,11621038 ! reproductive developmental process GO:0003006 127 89 0,000 0,11536111 0,1174029 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,11536111 0,11735097 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,11536111 0,11729909 ! regulation of T cell activation GO:0050863 128 89 0,000 0,11536111 0,11724726 ! leukocyte differentiation GO:0002521 143 90 0,000 0,11658179 0,11843556 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,11658179 0,11838327 ! hormone metabolic process GO:0042445 121 90 0,000 0,11658179 0,11833103 ! RNA localization GO:0006403 135 91 0,000 0,11780086 0,11951565 ! ATP metabolic process GO:0046034 137 91 0,000 0,11780086 0,11946295 ! response to virus GO:0009615 122 91 0,000 0,11780086 0,1194103 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,11901831 0,12059124 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,11901831 0,12053814 ! positive regulation of immune response GO:0050778 121 92 0,000 0,11901831 0,12048509 ! DNA recombination GO:0006310 146 92 0,000 0,11901831 0,12043208 ! sulfur metabolic process GO:0006790 118 92 0,000 0,11901831 0,12037912 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,12023416 0,12155541 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,12023416 0,12150201 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,12023416 0,12144865 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,12023416 0,12139533 ! electron transport chain GO:0022900 123 94 0,000 0,1214484 0,12256749 ! angiogenesis GO:0001525 149 95 0,000 0,12266103 0,123737 ! carboxylic acid transport GO:0046942 147 95 0,000 0,12266103 0,12368276 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,12387206 0,12484914 ! in utero embryonic development GO:0001701 147 96 0,000 0,12387206 0,12479445 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,12387206 0,12473981 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,12387206 0,12468522 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,12387206 0,12463068 ! protein maturation GO:0051604 129 96 0,000 0,12387206 0,12457618 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,12508148 0,1257375 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,12508148 0,12568257 ! calcium ion transport GO:0006816 167 99 0,000 0,12749554 0,12805228 ! extracellular structure organization GO:0043062 156 99 0,000 0,12749554 0,12799639 ! protein import GO:0017038 156 99 0,000 0,12749554 0,12794055 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,12749554 0,12788475 ! regulation of translation GO:0006417 151 100 0,000 0,12870017 0,12903678 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,12870017 0,12898056 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,12870017 0,12892438 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,12870017 0,12886826 ! divalent metal ion transport GO:0070838 171 100 0,000 0,12870017 0,12881218 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,12870017 0,12875615 ! protein localization in organelle GO:0033365 161 100 0,000 0,12870017 0,12870017