pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/54386-6-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 2,000 8,553E-07 2,089E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 2,000 4,041E-06 4,936E-03 ! muscle cell migration GO:0014812 8 5 1,000 6,418E-06 5,226E-03 ! response to UV GO:0009411 120 55 2,000 1,245E-05 7,603E-03 ! negative regulation of telomere maintenance GO:0032205 13 7 1,000 1,346E-05 6,578E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,794E-05 7,305E-03 ! regulation of Rac protein signal transduction GO:0035020 18 8 1,000 1,794E-05 6,262E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 1,000 1,794E-05 5,479E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 1,000 2,306E-05 6,259E-03 ! regulation of telomere maintenance GO:0032204 17 9 1,000 2,306E-05 5,633E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 2,361E-05 5,244E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 2,467E-05 5,023E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 2,804E-05 5,269E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 2,804E-05 4,893E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 2,881E-05 4,692E-03 ! induction of an organ GO:0001759 17 10 1,000 2,881E-05 4,398E-03 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 3,169E-05 4,555E-03 ! positive regulation of ligase activity GO:0051351 130 77 2,000 3,43E-05 4,655E-03 ! thyroid gland development GO:0030878 26 11 1,000 3,519E-05 4,525E-03 ! telomere maintenance via telomerase GO:0007004 24 11 1,000 3,519E-05 4,298E-03 GO:0010833|telomere maintenance via telomere lengthening, ! UV protection GO:0009650 20 11 1,000 3,519E-05 4,094E-03 ! thymus development GO:0048538 29 11 1,000 3,519E-05 3,908E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 3,704E-05 3,934E-03 ! developmental induction GO:0031128 22 12 1,000 4,221E-05 4,296E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of ligase activity GO:0051340 147 84 2,000 4,45E-05 4,349E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 1,000 4,986E-05 4,684E-03 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 4,986E-05 4,511E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 1,000 5,813E-05 5,072E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 5,813E-05 4,897E-03 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 5,813E-05 4,734E-03 ! RNA-dependent DNA replication GO:0006278 28 14 1,000 5,813E-05 4,581E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 6,031E-05 4,604E-03 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 6,031E-05 4,465E-03 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 6,837E-05 4,913E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 7,049E-05 4,92E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 7,658E-05 5,197E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 1,000 7,658E-05 5,057E-03 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 8,675E-05 5,577E-03 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 1,09E-04 6,826E-03 ! visual learning GO:0008542 38 19 1,000 1,09E-04 6,655E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 1,21E-04 7,211E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of intracellular transport GO:0032387 44 21 1,000 1,337E-04 7,776E-03 ! ureteric bud development GO:0001657 50 22 1,000 1,47E-04 8,35E-03 ! cell aging GO:0007569 48 22 1,000 1,47E-04 8,161E-03 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 1,47E-04 7,979E-03 ! activation of JUN kinase activity GO:0007257 47 22 1,000 1,47E-04 7,806E-03 ! axis specification GO:0009798 43 23 1,000 1,609E-04 8,363E-03 ! visual behavior GO:0007632 46 23 1,000 1,609E-04 8,189E-03 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 1,754E-04 8,746E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,906E-04 9,312E-03 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 2,064E-04 9,885E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 2,064E-04 9,695E-03 ! telomere organization GO:0032200 46 26 1,000 2,064E-04 9,512E-03 GO:0000723|telomere maintenance, ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 2,064E-04 9,336E-03 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 2,228E-04 9,895E-03 ! regulation of chromosome organization GO:0033044 49 27 1,000 2,228E-04 9,718E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 2,398E-04 0,01027683 ! fat cell differentiation GO:0045444 57 28 1,000 2,398E-04 0,01009964 ! base-excision repair GO:0006284 41 28 1,000 2,398E-04 9,928E-03 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 2,398E-04 9,763E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 2,574E-04 0,01030905 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 2,574E-04 0,01014277 ! metanephros development GO:0001656 81 32 1,000 3,14E-04 0,01217599 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 3,14E-04 0,01198574 ! negative regulation of protein transport GO:0051224 74 33 1,000 3,341E-04 0,01255637 ! inner ear morphogenesis GO:0042472 51 34 1,000 3,548E-04 0,01313236 ! cell fate specification GO:0001708 56 34 1,000 3,548E-04 0,01293635 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 3,761E-04 0,01351176 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 3,761E-04 0,01331594 ! negative regulation of DNA binding GO:0043392 67 36 1,000 3,98E-04 0,01389079 ! maintenance of protein location in cell GO:0032507 89 37 1,000 4,205E-04 0,0144704 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 4,437E-04 0,01505455 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 4,437E-04 0,01484832 ! negative regulation of binding GO:0051100 71 39 1,000 4,674E-04 0,01543163 ! learning GO:0007612 82 40 1,000 4,918E-04 0,01601913 ! maintenance of protein location GO:0045185 95 41 1,000 5,167E-04 0,01661064 ! ear morphogenesis GO:0042471 64 42 1,000 5,423E-04 0,01720595 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 5,423E-04 0,01698537 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 5,423E-04 0,01677036 ! epithelial cell differentiation GO:0030855 83 43 1,000 5,685E-04 0,01735979 ! striated muscle cell differentiation GO:0051146 91 43 1,000 5,685E-04 0,01714547 ! double-strand break repair GO:0006302 85 44 1,000 5,952E-04 0,01773391 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 6,226E-04 0,01832587 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 6,226E-04 0,0181077 ! keratinocyte differentiation GO:0030216 81 45 1,000 6,226E-04 0,01789467 ! maintenance of location in cell GO:0051651 101 45 1,000 6,226E-04 0,0176866 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 6,506E-04 0,01826876 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 6,506E-04 0,01806116 ! regulation of JNK cascade GO:0046328 104 47 1,000 6,792E-04 0,01864249 ! response to insulin stimulus GO:0032868 98 47 1,000 6,792E-04 0,01843535 ! positive regulation of cell cycle GO:0045787 96 48 1,000 7,083E-04 0,01901588 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 7,083E-04 0,01880919 ! response to calcium ion GO:0051592 94 49 1,000 7,381E-04 0,01938892 ! JNK cascade GO:0007254 106 49 1,000 7,381E-04 0,01918265 ! endocrine system development GO:0035270 109 50 1,000 7,685E-04 0,0197616 ! epidermal cell differentiation GO:0009913 87 50 1,000 7,685E-04 0,01955575 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 7,994E-04 0,02013393 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 8,31E-04 0,02071514 ! inner ear development GO:0048839 89 53 1,000 8,631E-04 0,02129928 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 8,631E-04 0,02108629 ! embryonic skeletal system development GO:0048706 101 54 1,000 8,959E-04 0,02166954 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 8,959E-04 0,02145709 ! skeletal muscle fiber development GO:0048741 130 56 1,000 9,631E-04 0,0228442 ! regulation of DNA replication GO:0006275 105 56 1,000 9,631E-04 0,02262454 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 9,977E-04 0,02321221 ! muscle fiber development GO:0048747 131 57 1,000 9,977E-04 0,02299323 ! nucleotide-excision repair GO:0006289 91 57 1,000 9,977E-04 0,02277834 ! regulation of intracellular transport GO:0032386 108 57 1,000 9,977E-04 0,02256743 ! aging GO:0007568 112 58 1,000 1,033E-03 0,02314727 ! maintenance of location GO:0051235 124 58 1,000 1,033E-03 0,02293684 ! kidney development GO:0001822 133 60 1,000 1,105E-03 0,02431447 ! regulation of homeostatic process GO:0032844 148 62 1,000 1,179E-03 0,0257187 ! skeletal system morphogenesis GO:0048705 118 63 1,000 1,217E-03 0,02631358 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 1,256E-03 0,02691054 ! ear development GO:0043583 114 66 1,000 1,335E-03 0,02835485 ! activation of MAPK activity GO:0000187 124 67 1,000 1,375E-03 0,02896071 ! regulation of cellular response to stress GO:0080135 142 68 1,000 1,416E-03 0,02956834 ! urogenital system development GO:0001655 149 69 1,000 1,458E-03 0,03017767 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 1,586E-03 0,03255334 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 1,674E-03 0,03407896 ! learning or memory GO:0007611 161 76 1,000 1,765E-03 0,03562573 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 1,905E-03 0,03813979 ! regulation of synaptic transmission GO:0050804 159 79 1,000 1,905E-03 0,03782971 ! negative regulation of organelle organization GO:0010639 181 80 1,000 1,952E-03 0,03846737 ! muscle cell differentiation GO:0042692 178 81 1,000 2,001E-03 0,03910595 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 2,001E-03 0,03879559 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 2,099E-03 0,0403857 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 2,15E-03 0,04102679 ! negative regulation of transport GO:0051051 164 85 1,000 2,2E-03 0,04166865 ! regulation of neuron differentiation GO:0045664 187 85 1,000 2,2E-03 0,04134812 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 2,2E-03 0,04103248 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 2,2E-03 0,04072163 ! regulation of protein transport GO:0051223 165 87 1,000 2,303E-03 0,04230859 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 167 89 1,000 2,409E-03 0,04391288 ! tube morphogenesis GO:0035239 194 89 1,000 2,409E-03 0,0435876 ! regulation of neurological system process GO:0031644 175 89 1,000 2,409E-03 0,04326711 ! response to inorganic substance GO:0010035 173 90 1,000 2,462E-03 0,04390529 ! positive regulation of protein modification process GO:0031401 156 90 1,000 2,462E-03 0,04358713 ! response to unfolded protein GO:0006986 139 90 1,000 2,462E-03 0,04327356 ! gland development GO:0048732 220 91 1,000 2,516E-03 0,04390779 ! response to protein stimulus GO:0051789 158 96 1,000 2,795E-03 0,04842456 ! regulation of protein localization GO:0032880 188 97 1,000 2,852E-03 0,04907107 ! skeletal muscle tissue development GO:0007519 223 100 1,000 3,028E-03 0,05172646 GO:0060538|skeletal muscle organ development, ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 4,073E-03 0,06910006 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 4,073E-03 0,0686235 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 4,073E-03 0,06815348 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,073E-03 0,06768985 ! positive regulation of helicase activity GO:0051096 12 5 0,000 4,073E-03 0,06723249 ! neuron fate determination GO:0048664 7 5 0,000 4,073E-03 0,06678126 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,073E-03 0,06633605 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 4,073E-03 0,06589674 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 4,073E-03 0,06546321 ! polyol transport GO:0015791 12 5 0,000 4,073E-03 0,06503535 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,073E-03 0,06461304 ! response to superoxide GO:0000303 10 5 0,000 4,073E-03 0,06419618 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,073E-03 0,06378467 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 4,073E-03 0,0633784 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 4,073E-03 0,06297727 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,073E-03 0,06258118 ! female meiosis GO:0007143 10 5 0,000 4,073E-03 0,06219005 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 4,073E-03 0,06180378 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,073E-03 0,06142227 ! hypothalamus development GO:0021854 9 5 0,000 4,073E-03 0,06104545 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 4,073E-03 0,06067322 ! cobalt ion transport GO:0006824 11 5 0,000 4,073E-03 0,0603055 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 4,073E-03 0,05994222 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 4,073E-03 0,05958328 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,073E-03 0,05922862 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,073E-03 0,05887815 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 4,073E-03 0,05853181 ! embryonic camera-type eye development GO:0031076 12 5 0,000 4,073E-03 0,05818952 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,073E-03 0,05785121 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,073E-03 0,05751681 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 4,073E-03 0,05718625 ! transposition GO:0032196 9 5 0,000 4,073E-03 0,05685948 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 4,073E-03 0,05653641 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 4,073E-03 0,056217 ! negative chemotaxis GO:0050919 16 5 0,000 4,073E-03 0,05590117 ! positive regulation of histone modification GO:0031058 6 5 0,000 4,073E-03 0,05558887 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,073E-03 0,05528005 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 4,073E-03 0,05497463 ! behavioral response to pain GO:0048266 10 5 0,000 4,073E-03 0,05467257 ! clathrin coat assembly GO:0048268 15 5 0,000 4,073E-03 0,05437381 ! Notch receptor processing GO:0007220 11 5 0,000 4,073E-03 0,05407831 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,073E-03 0,05378599 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 4,073E-03 0,05349682 ! micturition GO:0060073 9 5 0,000 4,073E-03 0,05321074 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,073E-03 0,0529277 ! copulation GO:0007620 9 5 0,000 4,073E-03 0,05264766 ! glial cell fate commitment GO:0021781 14 5 0,000 4,073E-03 0,05237057 ! protein maturation by protein folding GO:0022417 14 5 0,000 4,073E-03 0,05209638 ! bioluminescence GO:0008218 9 5 0,000 4,073E-03 0,05182504 ! spermidine metabolic process GO:0008216 7 5 0,000 4,073E-03 0,05155652 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,073E-03 0,05129076 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,073E-03 0,05102773 ! apoptotic cell clearance GO:0043277 23 5 0,000 4,073E-03 0,05076739 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,073E-03 0,05050969 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 4,073E-03 0,05025459 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,073E-03 0,05000205 ! grooming behavior GO:0007625 6 5 0,000 4,073E-03 0,04975204 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 4,073E-03 0,04950452 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,073E-03 0,04925945 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 4,073E-03 0,04901679 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,073E-03 0,04877651 ! response to protozoan GO:0001562 13 5 0,000 4,073E-03 0,04853858 ! positive regulation of glycolysis GO:0045821 13 5 0,000 4,073E-03 0,04830295 ! lymph vessel development GO:0001945 10 5 0,000 4,073E-03 0,0480696 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 4,073E-03 0,0478385 ! endochondral ossification GO:0001958 17 5 0,000 4,073E-03 0,04760961 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,073E-03 0,0473829 ! single strand break repair GO:0000012 8 5 0,000 4,073E-03 0,04715833 ! parathyroid gland development GO:0060017 14 5 0,000 4,073E-03 0,04693589 ! anagen GO:0042640 7 5 0,000 4,073E-03 0,04671553 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,073E-03 0,04649723 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,073E-03 0,04628097 ! cytokine secretion GO:0050663 15 5 0,000 4,073E-03 0,0460667 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 4,073E-03 0,04585442 ! ceramide catabolic process GO:0046514 7 5 0,000 4,073E-03 0,04564407 ! skeletal myofibril assembly GO:0014866 12 5 0,000 4,073E-03 0,04543565 ! smooth muscle tissue development GO:0048745 32 5 0,000 4,073E-03 0,04522913 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,073E-03 0,04502447 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,073E-03 0,04482166 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,073E-03 0,04462066 ! cardiac muscle fiber development GO:0048739 12 5 0,000 4,073E-03 0,04442146 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,073E-03 0,04422404 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 4,073E-03 0,04402835 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,073E-03 0,0438344 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 4,073E-03 0,04364214 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,073E-03 0,04345156 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 4,073E-03 0,04326264 ! glycine biosynthetic process GO:0006545 7 5 0,000 4,073E-03 0,04307536 ! microvillus organization GO:0032528 8 5 0,000 4,073E-03 0,04288969 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 4,073E-03 0,04270561 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 4,073E-03 0,04252311 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 4,073E-03 0,04234216 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 4,073E-03 0,04216275 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 4,073E-03 0,04198484 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 4,073E-03 0,04180844 ! polyol catabolic process GO:0046174 9 5 0,000 4,073E-03 0,04163351 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 4,073E-03 0,04146003 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 4,073E-03 0,041288 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 4,073E-03 0,04111739 ! mitochondrial fission GO:0000266 8 5 0,000 4,073E-03 0,04094818 ! sister chromatid cohesion GO:0007062 15 5 0,000 4,073E-03 0,04078036 ! response to tumor necrosis factor GO:0034612 10 5 0,000 4,073E-03 0,04061391 ! mRNA transcription GO:0009299 10 5 0,000 4,073E-03 0,04044881 ! nerve growth factor processing GO:0032455 9 5 0,000 4,073E-03 0,04028505 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 4,073E-03 0,04012261 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 4,073E-03 0,03996148 ! anaerobic glycolysis GO:0019642 6 5 0,000 4,073E-03 0,03980163 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,073E-03 0,03964306 ! monocyte activation GO:0042117 10 5 0,000 4,073E-03 0,03948575 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,073E-03 0,03932968 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,073E-03 0,03917484 ! response to food GO:0032094 6 5 0,000 4,073E-03 0,03902121 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,073E-03 0,03886878 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,073E-03 0,03871754 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 4,073E-03 0,03856747 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,073E-03 0,03841856 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 4,073E-03 0,0382708 ! forebrain neuron development GO:0021884 13 5 0,000 4,073E-03 0,03812417 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,073E-03 0,03797866 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 4,073E-03 0,03783425 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 4,073E-03 0,03769094 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,073E-03 0,03754871 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,073E-03 0,03740755 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 4,073E-03 0,03726745 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,073E-03 0,03712839 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 4,073E-03 0,03699036 ! lipid glycosylation GO:0030259 7 5 0,000 4,073E-03 0,03685336 ! nucleobase transport GO:0015851 6 5 0,000 4,073E-03 0,03671737 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,073E-03 0,03658238 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 4,073E-03 0,03644838 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 4,073E-03 0,03631536 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 4,073E-03 0,0361833 ! basic amino acid transport GO:0015802 12 5 0,000 4,073E-03 0,0360522 ! cellular glucose homeostasis GO:0001678 6 5 0,000 4,073E-03 0,03592205 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 4,073E-03 0,03579284 ! actin nucleation GO:0045010 11 5 0,000 4,073E-03 0,03566455 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,073E-03 0,03553717 ! depurination GO:0045007 5 5 0,000 4,073E-03 0,03541071 ! depyrimidination GO:0045008 10 5 0,000 4,073E-03 0,03528514 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,073E-03 0,03516045 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,073E-03 0,03503665 ! G2/M transition checkpoint GO:0031576 8 5 0,000 4,073E-03 0,03491371 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,073E-03 0,03479164 ! zinc ion homeostasis GO:0055069 9 5 0,000 4,073E-03 0,03467041 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 4,073E-03 0,03455003 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 4,073E-03 0,03443048 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,073E-03 0,03431175 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,073E-03 0,03419384 ! activated T cell proliferation GO:0050798 16 5 0,000 4,073E-03 0,03407674 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,073E-03 0,03396044 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 4,073E-03 0,03384493 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,073E-03 0,0337302 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,073E-03 0,03361624 ! gamma-delta T cell activation GO:0046629 6 5 0,000 4,073E-03 0,03350306 ! response to arsenic GO:0046685 11 5 0,000 4,073E-03 0,03339063 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 4,073E-03 0,03327896 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,073E-03 0,03316803 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 4,073E-03 0,03305783 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 4,073E-03 0,03294837 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 4,073E-03 0,03283963 ! response to mercury ion GO:0046689 8 5 0,000 4,073E-03 0,03273161 ! response to cadmium ion GO:0046686 7 5 0,000 4,073E-03 0,03262429 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 4,073E-03 0,03251767 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 4,073E-03 0,03241175 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 4,073E-03 0,03230652 ! bile acid biosynthetic process GO:0006699 7 5 0,000 4,073E-03 0,03220197 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 4,073E-03 0,03209809 ! ganglioside catabolic process GO:0006689 12 5 0,000 4,073E-03 0,03199488 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,073E-03 0,03189233 ! decidualization GO:0046697 11 5 0,000 4,073E-03 0,03179044 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 4,073E-03 0,0316892 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 4,073E-03 0,0315886 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 4,073E-03 0,03148863 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 4,073E-03 0,0313893 ! embryonic cleavage GO:0040016 6 5 0,000 4,073E-03 0,03129059 ! peroxisome fission GO:0016559 5 5 0,000 4,073E-03 0,0311925 ! histone demethylation GO:0016577 13 5 0,000 4,073E-03 0,03109503 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 4,073E-03 0,03099816 ! mitotic recombination GO:0006312 9 5 0,000 4,073E-03 0,03090189 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 4,073E-03 0,03080622 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,073E-03 0,03071114 ! metaphase plate congression GO:0051310 7 5 0,000 4,073E-03 0,03061664 ! regulation of sterol transport GO:0032371 7 5 0,000 4,073E-03 0,03052272 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,073E-03 0,03042938 ! enteric nervous system development GO:0048484 8 5 0,000 4,073E-03 0,03033661 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 4,073E-03 0,0302444 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 4,073E-03 0,03015275 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 4,073E-03 0,03006166 ! muscle cell proliferation GO:0033002 12 5 0,000 4,073E-03 0,02997111 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,073E-03 0,02988111 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 4,073E-03 0,02979164 ! B cell homeostasis GO:0001782 13 5 0,000 4,073E-03 0,02970271 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 4,073E-03 0,02961431 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,073E-03 0,02952643 ! metaphase GO:0051323 11 5 0,000 4,073E-03 0,02943908 ! melatonin biosynthetic process GO:0030187 7 5 0,000 4,073E-03 0,02935224 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 4,073E-03 0,02926591 ! cellular response to nutrient GO:0031670 8 5 0,000 4,073E-03 0,02918008 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,073E-03 0,02909476 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 4,073E-03 0,02900994 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 4,073E-03 0,02892561 ! regulation of hair follicle development GO:0051797 10 5 0,000 4,073E-03 0,02884176 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 4,073E-03 0,02875841 ! response to redox state GO:0051775 6 5 0,000 4,073E-03 0,02867553 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 4,073E-03 0,02859313 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 4,073E-03 0,0285112 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,073E-03 0,02842974 ! brown fat cell differentiation GO:0050873 7 5 0,000 4,073E-03 0,02834874 ! regulation of telomerase activity GO:0051972 7 5 0,000 4,073E-03 0,0282682 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,073E-03 0,02818813 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 4,073E-03 0,0281085 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,073E-03 0,02802932 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 4,073E-03 0,02795058 ! striatum development GO:0021756 14 5 0,000 4,073E-03 0,02787229 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 4,073E-03 0,02779444 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,073E-03 0,02771701 ! glial cell migration GO:0008347 10 5 0,000 4,073E-03 0,02764002 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,073E-03 0,02756346 ! neural plate morphogenesis GO:0001839 7 5 0,000 4,073E-03 0,02748732 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 4,073E-03 0,02741159 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,073E-03 0,02733629 ! T cell activation during immune response GO:0002286 9 5 0,000 4,073E-03 0,02726139 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,073E-03 0,02718691 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,073E-03 0,02711283 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 4,073E-03 0,02703915 ! neuroprotection GO:0043526 8 5 0,000 4,073E-03 0,02696588 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,073E-03 0,02689299 ! regulation of sensory perception GO:0051931 8 5 0,000 4,073E-03 0,02682051 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,073E-03 0,02674841 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,073E-03 0,0266767 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 4,073E-03 0,02660537 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 4,073E-03 0,02653442 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,073E-03 0,02646385 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 4,073E-03 0,02639366 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,073E-03 0,02632383 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 4,073E-03 0,02625438 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 4,073E-03 0,02618528 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 4,073E-03 0,02611656 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,073E-03 0,02604819 ! spindle assembly GO:0051225 6 5 0,000 4,073E-03 0,02598018 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,073E-03 0,02591252 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,073E-03 0,02584522 ! protein palmitoylation GO:0018345 12 5 0,000 4,073E-03 0,02577826 ! drug metabolic process GO:0017144 7 5 0,000 4,073E-03 0,02571165 ! stem cell division GO:0017145 11 5 0,000 4,073E-03 0,02564538 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,073E-03 0,02557946 ! organ regeneration GO:0031100 7 5 0,000 4,073E-03 0,02551387 ! carnitine metabolic process GO:0009437 8 5 0,000 4,073E-03 0,02544861 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,073E-03 0,02538369 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 4,886E-03 0,03037096 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 4,886E-03 0,03029388 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 4,886E-03 0,03021719 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 4,886E-03 0,03014088 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 4,886E-03 0,03006496 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 4,886E-03 0,02998942 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 4,886E-03 0,02991426 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 4,886E-03 0,02983947 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 4,886E-03 0,02976506 ! response to oxygen radical GO:0000305 11 6 0,000 4,886E-03 0,02969102 ! positive regulation of axon extension GO:0045773 13 6 0,000 4,886E-03 0,02961734 ! myoblast cell fate commitment GO:0048625 18 6 0,000 4,886E-03 0,02954403 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 4,886E-03 0,02947108 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 4,886E-03 0,02939849 ! regulation of interferon-beta production GO:0032648 8 6 0,000 4,886E-03 0,02932626 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 4,886E-03 0,02925438 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 4,886E-03 0,02918286 ! forebrain regionalization GO:0021871 9 6 0,000 4,886E-03 0,02911168 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 4,886E-03 0,02904085 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 4,886E-03 0,02897036 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 4,886E-03 0,02890021 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 4,886E-03 0,02883041 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 4,886E-03 0,02876094 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 4,886E-03 0,0286918 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 4,886E-03 0,02862299 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 4,886E-03 0,02855452 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 4,886E-03 0,02848637 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 4,886E-03 0,02841854 ! malate metabolic process GO:0006108 13 6 0,000 4,886E-03 0,02835104 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 4,886E-03 0,02828386 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 4,886E-03 0,02821699 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 4,886E-03 0,02815044 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 4,886E-03 0,02808421 ! protein refolding GO:0042026 15 6 0,000 4,886E-03 0,02801828 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 4,886E-03 0,02795267 ! opsonization GO:0008228 8 6 0,000 4,886E-03 0,02788736 ! mating behavior GO:0007617 7 6 0,000 4,886E-03 0,02782235 ! erythrocyte maturation GO:0043249 8 6 0,000 4,886E-03 0,02775765 ! embryonic hemopoiesis GO:0035162 16 6 0,000 4,886E-03 0,02769325 ! protein amino acid dealkylation GO:0008214 15 6 0,000 4,886E-03 0,02762914 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 4,886E-03 0,02756533 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 4,886E-03 0,02750182 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 4,886E-03 0,02743859 ! response to interferon-gamma GO:0034341 16 6 0,000 4,886E-03 0,02737566 ! toxin metabolic process GO:0009404 11 6 0,000 4,886E-03 0,02731302 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 4,886E-03 0,02725066 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 4,886E-03 0,02718858 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 4,886E-03 0,02712679 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 4,886E-03 0,02706528 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 4,886E-03 0,02700405 ! cGMP-mediated signaling GO:0019934 14 6 0,000 4,886E-03 0,02694309 ! dorsal spinal cord development GO:0021516 10 6 0,000 4,886E-03 0,02688241 ! activation of MAPKKK activity GO:0000185 12 6 0,000 4,886E-03 0,026822 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 4,886E-03 0,02676186 ! thymic T cell selection GO:0045061 16 6 0,000 4,886E-03 0,02670199 ! sphingoid catabolic process GO:0046521 8 6 0,000 4,886E-03 0,02664239 ! protein lipoylation GO:0009249 10 6 0,000 4,886E-03 0,02658305 ! transepithelial chloride transport GO:0030321 12 6 0,000 4,886E-03 0,02652397 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 4,886E-03 0,02646516 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 4,886E-03 0,02640661 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 4,886E-03 0,02634832 ! glutamate catabolic process GO:0006538 12 6 0,000 4,886E-03 0,02629028 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 4,886E-03 0,0262325 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 4,886E-03 0,02617498 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 4,886E-03 0,0261177 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 4,886E-03 0,02606067 ! hyperosmotic response GO:0006972 10 6 0,000 4,886E-03 0,0260039 ! L-serine biosynthetic process GO:0006564 7 6 0,000 4,886E-03 0,02594737 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 4,886E-03 0,02589108 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 4,886E-03 0,02583504 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 4,886E-03 0,02577924 ! urea metabolic process GO:0019627 7 6 0,000 4,886E-03 0,02572368 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 4,886E-03 0,02566836 ! neutrophil activation GO:0042119 7 6 0,000 4,886E-03 0,02561328 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 4,886E-03 0,02555843 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 4,886E-03 0,02550382 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 4,886E-03 0,02544944 ! paraxial mesoderm development GO:0048339 16 6 0,000 4,886E-03 0,02539529 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 4,886E-03 0,02534138 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 4,886E-03 0,02528769 ! neuron apoptosis GO:0051402 15 6 0,000 4,886E-03 0,02523423 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 4,886E-03 0,02518099 ! T cell mediated immunity GO:0002456 17 6 0,000 4,886E-03 0,02512798 ! negative regulation of platelet activation GO:0010544 9 6 0,000 4,886E-03 0,02507519 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 4,886E-03 0,02502262 ! carnitine transport GO:0015879 10 6 0,000 4,886E-03 0,02497027 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,886E-03 0,02491814 ! positive regulation of exocytosis GO:0045921 11 6 0,000 4,886E-03 0,02486623 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 4,886E-03 0,02481453 ! early endosome to late endosome transport GO:0045022 16 6 0,000 4,886E-03 0,02476305 ! 5S class rRNA transcription GO:0042791 13 6 0,000 4,886E-03 0,02471178 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 4,886E-03 0,02466072 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 4,886E-03 0,02460987 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 4,886E-03 0,02455924 ! sodium ion homeostasis GO:0055078 12 6 0,000 4,886E-03 0,02450881 ! establishment of spindle localization GO:0051293 16 6 0,000 4,886E-03 0,02445858 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 4,886E-03 0,02440857 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 4,886E-03 0,02435875 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 4,886E-03 0,02430914 ! response to UV-C GO:0010225 14 6 0,000 4,886E-03 0,02425973 ! astrocyte development GO:0014002 16 6 0,000 4,886E-03 0,02421052 ! protein targeting to lysosome GO:0006622 12 6 0,000 4,886E-03 0,02416152 ! purine base biosynthetic process GO:0009113 17 6 0,000 4,886E-03 0,0241127 ! interaction with symbiont GO:0051702 14 6 0,000 4,886E-03 0,02406409 ! regulation of dendrite development GO:0050773 16 6 0,000 4,886E-03 0,02401567 ! peptidyl-arginine modification GO:0018195 13 6 0,000 4,886E-03 0,02396745 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 4,886E-03 0,02391942 ! response to copper ion GO:0046688 10 6 0,000 4,886E-03 0,02387158 ! response to exogenous dsRNA GO:0043330 13 6 0,000 4,886E-03 0,02382393 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 4,886E-03 0,02377647 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,886E-03 0,0237292 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 4,886E-03 0,02368212 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 4,886E-03 0,02363523 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 4,886E-03 0,02358852 ! regulation of dopamine secretion GO:0014059 14 6 0,000 4,886E-03 0,02354199 ! nucleoside catabolic process GO:0009164 10 6 0,000 4,886E-03 0,02349565 ! hair follicle maturation GO:0048820 8 6 0,000 4,886E-03 0,02344949 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 4,886E-03 0,02340351 ! Schwann cell development GO:0014044 15 6 0,000 4,886E-03 0,02335771 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 4,886E-03 0,02331209 ! response to pheromone GO:0019236 6 6 0,000 4,886E-03 0,02326664 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 4,886E-03 0,02322138 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 4,886E-03 0,02317629 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 4,886E-03 0,02313137 ! base conversion or substitution editing GO:0016553 6 6 0,000 4,886E-03 0,02308663 ! subpallium development GO:0021544 15 6 0,000 4,886E-03 0,02304206 ! neural tube patterning GO:0021532 8 6 0,000 4,886E-03 0,02299767 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 4,886E-03 0,02295344 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 4,886E-03 0,02290938 ! maintenance of organ identity GO:0048496 9 6 0,000 4,886E-03 0,0228655 ! G2 phase GO:0051319 16 6 0,000 4,886E-03 0,02282178 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 4,886E-03 0,02277822 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 4,886E-03 0,02273484 ! oxygen homeostasis GO:0032364 10 6 0,000 4,886E-03 0,02269161 ! establishment of planar polarity GO:0001736 7 6 0,000 4,886E-03 0,02264856 ! regulation of mast cell activation GO:0033003 13 6 0,000 4,886E-03 0,02260566 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 4,886E-03 0,02256293 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 4,886E-03 0,02252036 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 4,886E-03 0,02247794 ! receptor internalization GO:0031623 11 6 0,000 4,886E-03 0,02243569 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 4,886E-03 0,0223936 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 4,886E-03 0,02235166 ! neutrophil homeostasis GO:0001780 11 6 0,000 4,886E-03 0,02230989 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,886E-03 0,02226826 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 4,886E-03 0,02222679 ! protein deubiquitination GO:0016579 16 6 0,000 4,886E-03 0,02218548 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 4,886E-03 0,02214432 ! protein destabilization GO:0031648 9 6 0,000 4,886E-03 0,02210331 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 4,886E-03 0,02206246 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 4,886E-03 0,02202175 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 4,886E-03 0,02198119 ! regulation of viral transcription GO:0046782 11 6 0,000 4,886E-03 0,02194079 ! progesterone metabolic process GO:0042448 12 6 0,000 4,886E-03 0,02190053 ! negative regulation of axon extension GO:0030517 24 6 0,000 4,886E-03 0,02186042 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 4,886E-03 0,02182045 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 4,886E-03 0,02178064 ! triglyceride catabolic process GO:0019433 10 6 0,000 4,886E-03 0,02174096 ! determination of adult lifespan GO:0008340 17 6 0,000 4,886E-03 0,02170143 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 4,886E-03 0,02166205 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 4,886E-03 0,02162281 ! neural plate development GO:0001840 9 6 0,000 4,886E-03 0,0215837 ! catecholamine transport GO:0051937 9 6 0,000 4,886E-03 0,02154474 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 4,886E-03 0,02150593 ! sensory cilium assembly GO:0035058 10 6 0,000 4,886E-03 0,02146725 ! organ or tissue specific immune response GO:0002251 8 6 0,000 4,886E-03 0,0214287 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 4,886E-03 0,0213903 ! maternal placenta development GO:0001893 12 6 0,000 4,886E-03 0,02135204 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 4,886E-03 0,02131391 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 4,886E-03 0,02127592 ! negative regulation of B cell activation GO:0050869 14 6 0,000 4,886E-03 0,02123806 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 4,886E-03 0,02120034 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 4,886E-03 0,02116275 ! positive regulation of coagulation GO:0050820 13 6 0,000 4,886E-03 0,02112529 ! cellular anion homeostasis GO:0030002 11 6 0,000 4,886E-03 0,02108797 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 5,698E-03 0,02454957 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 5,698E-03 0,02450635 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 5,698E-03 0,02446328 ! behavioral response to cocaine GO:0048148 14 7 0,000 5,698E-03 0,02442036 ! regulation of helicase activity GO:0051095 16 7 0,000 5,698E-03 0,02437759 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 5,698E-03 0,02433497 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 5,698E-03 0,0242925 ! sleep GO:0030431 16 7 0,000 5,698E-03 0,02425018 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 5,698E-03 0,02420801 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 5,698E-03 0,02416598 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 5,698E-03 0,0241241 ! prostate gland development GO:0030850 14 7 0,000 5,698E-03 0,02408236 ! nucleotide-sugar transport GO:0015780 11 7 0,000 5,698E-03 0,02404077 ! synaptonemal complex assembly GO:0007130 10 7 0,000 5,698E-03 0,02399932 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 5,698E-03 0,02395801 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 5,698E-03 0,02391685 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 5,698E-03 0,02387582 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 5,698E-03 0,02383494 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 5,698E-03 0,0237942 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 5,698E-03 0,02375359 ! SMAD protein complex assembly GO:0007183 13 7 0,000 5,698E-03 0,02371313 ! glycolipid transport GO:0046836 11 7 0,000 5,698E-03 0,0236728 ! protein amino acid sulfation GO:0006477 10 7 0,000 5,698E-03 0,02363261 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 5,698E-03 0,02359255 ! neuron adhesion GO:0007158 14 7 0,000 5,698E-03 0,02355263 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 5,698E-03 0,02351285 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 5,698E-03 0,0234732 ! establishment of tissue polarity GO:0007164 8 7 0,000 5,698E-03 0,02343368 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 5,698E-03 0,02339429 ! mRNA stabilization GO:0048255 18 7 0,000 5,698E-03 0,02335504 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 5,698E-03 0,02331592 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 5,698E-03 0,02327693 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 5,698E-03 0,02323807 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 5,698E-03 0,02319934 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 5,698E-03 0,02316074 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 5,698E-03 0,02312227 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 5,698E-03 0,02308392 ! lipoprotein transport GO:0042953 14 7 0,000 5,698E-03 0,0230457 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 5,698E-03 0,02300761 ! rhythmic behavior GO:0007622 17 7 0,000 5,698E-03 0,02296965 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 5,698E-03 0,0229318 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 5,698E-03 0,02289409 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 5,698E-03 0,02285649 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 5,698E-03 0,02281902 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 5,698E-03 0,02278168 ! regulation of odontogenesis GO:0042481 14 7 0,000 5,698E-03 0,02274445 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 5,698E-03 0,02270735 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 5,698E-03 0,02267037 ! mechanosensory behavior GO:0007638 16 7 0,000 5,698E-03 0,0226335 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 5,698E-03 0,02259676 ! positive regulation of isotype switching GO:0045830 17 7 0,000 5,698E-03 0,02256014 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 5,698E-03 0,02252363 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 5,698E-03 0,02248725 ! protein-cofactor linkage GO:0018065 13 7 0,000 5,698E-03 0,02245098 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 5,698E-03 0,02241482 ! spinal cord patterning GO:0021511 14 7 0,000 5,698E-03 0,02237879 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 5,698E-03 0,02234287 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 5,698E-03 0,02230706 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 5,698E-03 0,02227137 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 5,698E-03 0,02223579 ! adrenal gland development GO:0030325 17 7 0,000 5,698E-03 0,02220033 ! cysteine metabolic process GO:0006534 13 7 0,000 5,698E-03 0,02216498 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 5,698E-03 0,02212974 ! ovulation GO:0030728 10 7 0,000 5,698E-03 0,02209461 ! adenohypophysis development GO:0021984 11 7 0,000 5,698E-03 0,0220596 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 5,698E-03 0,02202469 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 5,698E-03 0,0219899 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 5,698E-03 0,02195521 ! microtubule nucleation GO:0007020 21 7 0,000 5,698E-03 0,02192064 ! proline biosynthetic process GO:0006561 10 7 0,000 5,698E-03 0,02188617 ! tryptophan metabolic process GO:0006568 11 7 0,000 5,698E-03 0,02185181 ! thyroid hormone generation GO:0006590 13 7 0,000 5,698E-03 0,02181756 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 5,698E-03 0,02178342 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 5,698E-03 0,02174938 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 5,698E-03 0,02171545 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 5,698E-03 0,02168163 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 5,698E-03 0,02164791 ! galactose metabolic process GO:0006012 13 7 0,000 5,698E-03 0,02161429 ! vesicle fusion GO:0006906 20 7 0,000 5,698E-03 0,02158078 ! response to dietary excess GO:0002021 8 7 0,000 5,698E-03 0,02154738 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 5,698E-03 0,02151407 ! intracellular pH reduction GO:0051452 13 7 0,000 5,698E-03 0,02148087 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 5,698E-03 0,02144777 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 5,698E-03 0,02141478 ! organ growth GO:0035265 15 7 0,000 5,698E-03 0,02138188 ! nucleoside transport GO:0015858 11 7 0,000 5,698E-03 0,02134909 ! nucleoside salvage GO:0043174 11 7 0,000 5,698E-03 0,02131639 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 5,698E-03 0,0212838 ! male sex determination GO:0030238 15 7 0,000 5,698E-03 0,02125131 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 5,698E-03 0,02121891 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 5,698E-03 0,02118661 ! parturition GO:0007567 16 7 0,000 5,698E-03 0,02115441 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 5,698E-03 0,02112231 ! rRNA modification GO:0000154 14 7 0,000 5,698E-03 0,02109031 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 5,698E-03 0,0210584 ! spindle checkpoint GO:0031577 16 7 0,000 5,698E-03 0,02102659 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 5,698E-03 0,02099488 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 5,698E-03 0,02096326 ! monocyte differentiation GO:0030224 16 7 0,000 5,698E-03 0,02093174 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 5,698E-03 0,02090031 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 5,698E-03 0,02086897 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 5,698E-03 0,02083773 ! hyaluronan metabolic process GO:0030212 9 7 0,000 5,698E-03 0,02080658 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 5,698E-03 0,02077553 ! anterograde axon cargo transport GO:0008089 18 7 0,000 5,698E-03 0,02074457 ! fibrinolysis GO:0042730 11 7 0,000 5,698E-03 0,0207137 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 5,698E-03 0,02068292 ! skeletal muscle contraction GO:0003009 8 7 0,000 5,698E-03 0,02065223 ! eating behavior GO:0042755 8 7 0,000 5,698E-03 0,02062164 ! B cell lineage commitment GO:0002326 21 7 0,000 5,698E-03 0,02059113 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 5,698E-03 0,02056072 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 5,698E-03 0,02053039 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 5,698E-03 0,02050015 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 5,698E-03 0,02047001 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 5,698E-03 0,02043995 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 5,698E-03 0,02040998 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 5,698E-03 0,0203801 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 5,698E-03 0,0203503 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 5,698E-03 0,02032059 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 5,698E-03 0,02029097 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 5,698E-03 0,02026143 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 5,698E-03 0,02023198 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 5,698E-03 0,02020262 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 5,698E-03 0,02017334 ! histone ubiquitination GO:0016574 9 7 0,000 5,698E-03 0,02014415 ! regulation of meiosis GO:0040020 12 7 0,000 5,698E-03 0,02011504 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 5,698E-03 0,02008601 ! T cell lineage commitment GO:0002360 16 7 0,000 5,698E-03 0,02005707 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 5,698E-03 0,02002821 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 5,698E-03 0,01999943 ! membrane to membrane docking GO:0022614 14 7 0,000 5,698E-03 0,01997074 ! transcription termination GO:0006353 14 7 0,000 5,698E-03 0,01994213 ! coenzyme A metabolic process GO:0015936 12 7 0,000 5,698E-03 0,0199136 ! anaphase GO:0051322 18 7 0,000 5,698E-03 0,01988515 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 5,698E-03 0,01985678 ! axonal fasciculation GO:0007413 19 7 0,000 5,698E-03 0,0198285 ! negative regulation of nuclear division GO:0051784 15 7 0,000 5,698E-03 0,01980029 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 5,698E-03 0,01977217 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 5,698E-03 0,01974412 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 5,698E-03 0,01971615 ! diuresis GO:0030146 12 7 0,000 5,698E-03 0,01968827 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 5,698E-03 0,01966046 ! thiamin metabolic process GO:0006772 7 7 0,000 5,698E-03 0,01963273 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 5,698E-03 0,01960508 ! antibiotic transport GO:0042891 9 7 0,000 5,698E-03 0,0195775 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 5,698E-03 0,01955001 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 5,698E-03 0,01952259 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 5,698E-03 0,01949524 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 5,698E-03 0,01946798 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 5,698E-03 0,01944079 ! melanin biosynthetic process GO:0042438 10 7 0,000 5,698E-03 0,01941367 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 5,698E-03 0,01938664 ! dopamine biosynthetic process GO:0042416 18 7 0,000 5,698E-03 0,01935967 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 5,698E-03 0,01933278 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 5,698E-03 0,01930597 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 5,698E-03 0,01927923 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 5,698E-03 0,01925257 ! endosome to lysosome transport GO:0008333 12 7 0,000 5,698E-03 0,01922597 ! protein modification by small protein removal GO:0070646 19 7 0,000 5,698E-03 0,01919946 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 5,698E-03 0,01917301 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 5,698E-03 0,01914664 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 5,698E-03 0,01912034 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 5,698E-03 0,01909411 ! muscle adaptation GO:0043500 13 7 0,000 5,698E-03 0,01906795 ! embryonic heart tube development GO:0035050 14 7 0,000 5,698E-03 0,01904187 ! retina homeostasis GO:0001895 12 7 0,000 5,698E-03 0,01901585 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 5,698E-03 0,01898991 ! protein amino acid prenylation GO:0018346 19 7 0,000 5,698E-03 0,01896404 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 5,698E-03 0,01893824 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 5,698E-03 0,01891251 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 6,509E-03 0,02157647 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 6,509E-03 0,02154723 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 6,509E-03 0,02151808 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 6,509E-03 0,021489 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 6,509E-03 0,02146 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 6,509E-03 0,02143108 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 6,509E-03 0,02140223 ! male meiosis GO:0007140 9 8 0,000 6,509E-03 0,02137347 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 6,509E-03 0,02134478 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 6,509E-03 0,02131616 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 6,509E-03 0,02128763 ! meiotic prophase I GO:0007128 14 8 0,000 6,509E-03 0,02125917 ! response to zinc ion GO:0010043 12 8 0,000 6,509E-03 0,02123079 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 6,509E-03 0,02120248 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 6,509E-03 0,02117425 ! oligopeptide transport GO:0006857 16 8 0,000 6,509E-03 0,02114609 ! actin-myosin filament sliding GO:0033275 13 8 0,000 6,509E-03 0,02111801 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 6,509E-03 0,02109 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 6,509E-03 0,02106206 ! signal peptide processing GO:0006465 12 8 0,000 6,509E-03 0,0210342 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 6,509E-03 0,02100642 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 6,509E-03 0,0209787 ! macrophage chemotaxis GO:0048246 12 8 0,000 6,509E-03 0,02095106 ! succinate metabolic process GO:0006105 17 8 0,000 6,509E-03 0,0209235 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 6,509E-03 0,020896 ! membrane hyperpolarization GO:0060081 11 8 0,000 6,509E-03 0,02086858 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 6,509E-03 0,02084123 ! estrogen metabolic process GO:0008210 17 8 0,000 6,509E-03 0,02081395 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 6,509E-03 0,02078674 ! T-helper 1 type immune response GO:0042088 12 8 0,000 6,509E-03 0,02075961 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 6,509E-03 0,02073254 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 6,509E-03 0,02070554 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,509E-03 0,02067862 ! reflex GO:0060004 17 8 0,000 6,509E-03 0,02065176 ! endothelial cell differentiation GO:0045446 17 8 0,000 6,509E-03 0,02062498 ! glycerolipid catabolic process GO:0046503 14 8 0,000 6,509E-03 0,02059826 ! hemoglobin metabolic process GO:0020027 14 8 0,000 6,509E-03 0,02057161 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 6,509E-03 0,02054504 ! pigment granule organization GO:0048753 17 8 0,000 6,509E-03 0,02051853 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 6,509E-03 0,02049209 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 6,509E-03 0,02046571 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 6,509E-03 0,02043941 ! astrocyte differentiation GO:0048708 19 8 0,000 6,509E-03 0,02041317 ! histidine catabolic process GO:0006548 10 8 0,000 6,509E-03 0,020387 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 6,509E-03 0,02036089 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 6,509E-03 0,02033486 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 6,509E-03 0,02030889 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 6,509E-03 0,02028298 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 6,509E-03 0,02025714 ! regulation of pigmentation during development GO:0048070 25 8 0,000 6,509E-03 0,02023137 ! melanin metabolic process GO:0006582 17 8 0,000 6,509E-03 0,02020566 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 6,509E-03 0,02018002 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 6,509E-03 0,02015445 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 6,509E-03 0,02012893 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 6,509E-03 0,02010349 ! macrophage activation GO:0042116 13 8 0,000 6,509E-03 0,0200781 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 6,509E-03 0,02005278 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 6,509E-03 0,02002753 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 6,509E-03 0,02000234 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 6,509E-03 0,01997721 ! purine salvage GO:0043101 12 8 0,000 6,509E-03 0,01995214 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 6,509E-03 0,01992714 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,509E-03 0,0199022 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 6,509E-03 0,01987732 ! osteoblast development GO:0002076 17 8 0,000 6,509E-03 0,01985251 ! positive regulation of vasodilation GO:0045909 14 8 0,000 6,509E-03 0,01982775 ! negative regulation of translational initiation GO:0045947 12 8 0,000 6,509E-03 0,01980306 ! Schwann cell differentiation GO:0014037 21 8 0,000 6,509E-03 0,01977843 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 6,509E-03 0,01975386 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 6,509E-03 0,01972935 ! response to UV-B GO:0010224 17 8 0,000 6,509E-03 0,0197049 ! protein targeting to vacuole GO:0006623 14 8 0,000 6,509E-03 0,01968052 ! protein retention in ER lumen GO:0006621 14 8 0,000 6,509E-03 0,01965619 ! intermediate filament organization GO:0045109 12 8 0,000 6,509E-03 0,01963192 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 6,509E-03 0,01960772 ! cellular extravasation GO:0045123 13 8 0,000 6,509E-03 0,01958357 ! cardiac muscle cell development GO:0055013 14 8 0,000 6,509E-03 0,01955948 ! response to antibiotic GO:0046677 11 8 0,000 6,509E-03 0,01953545 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 6,509E-03 0,01951148 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 6,509E-03 0,01948757 ! DNA topological change GO:0006265 12 8 0,000 6,509E-03 0,01946372 ! response to tropane GO:0014073 15 8 0,000 6,509E-03 0,01943992 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 6,509E-03 0,01941619 ! melanosome transport GO:0032402 13 8 0,000 6,509E-03 0,01939251 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 6,509E-03 0,01936889 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 6,509E-03 0,01934533 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 6,509E-03 0,01932182 ! mast cell activation GO:0045576 14 8 0,000 6,509E-03 0,01929837 ! multicellular organismal aging GO:0010259 20 8 0,000 6,509E-03 0,01927498 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 6,509E-03 0,01925164 ! gas homeostasis GO:0033483 14 8 0,000 6,509E-03 0,01922837 ! dendrite morphogenesis GO:0048813 14 8 0,000 6,509E-03 0,01920514 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 6,509E-03 0,01918198 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 6,509E-03 0,01915887 ! nucleosome disassembly GO:0006337 14 8 0,000 6,509E-03 0,01913581 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 6,509E-03 0,01911281 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 6,509E-03 0,01908987 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 6,509E-03 0,01906698 ! establishment of chromosome localization GO:0051303 14 8 0,000 6,509E-03 0,01904414 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 6,509E-03 0,01902136 ! intracellular lipid transport GO:0032365 16 8 0,000 6,509E-03 0,01899864 ! response to tumor cell GO:0002347 16 8 0,000 6,509E-03 0,01897596 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 6,509E-03 0,01895335 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 6,509E-03 0,01893078 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 6,509E-03 0,01890827 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 6,509E-03 0,01888582 ! positive regulation of epidermis development GO:0045684 13 8 0,000 6,509E-03 0,01886341 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 6,509E-03 0,01884106 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 6,509E-03 0,01881877 ! hormone catabolic process GO:0042447 17 8 0,000 6,509E-03 0,01879652 ! glycolipid catabolic process GO:0019377 16 8 0,000 6,509E-03 0,01877433 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 6,509E-03 0,01875219 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 6,509E-03 0,0187301 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 6,509E-03 0,01870807 ! positive regulation of glucose import GO:0046326 8 8 0,000 6,509E-03 0,01868608 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 6,509E-03 0,01866415 ! adult feeding behavior GO:0008343 10 8 0,000 6,509E-03 0,01864227 ! ATP catabolic process GO:0006200 11 8 0,000 6,509E-03 0,01862044 ! blastocyst growth GO:0001832 19 8 0,000 6,509E-03 0,01859866 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 6,509E-03 0,01857694 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 6,509E-03 0,01855526 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 6,509E-03 0,01853363 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 6,509E-03 0,01851206 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 6,509E-03 0,01849053 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 6,509E-03 0,01846906 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 6,509E-03 0,01844763 ! amino sugar catabolic process GO:0046348 11 8 0,000 6,509E-03 0,01842626 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 6,509E-03 0,01840493 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 6,509E-03 0,01838365 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 6,509E-03 0,01836242 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 6,509E-03 0,01834124 ! behavioral response to nicotine GO:0035095 12 8 0,000 6,509E-03 0,01832011 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 6,509E-03 0,01829903 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 6,509E-03 0,018278 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 6,509E-03 0,01825701 ! NAD biosynthetic process GO:0009435 17 8 0,000 6,509E-03 0,01823608 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 6,509E-03 0,01821519 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 6,509E-03 0,01819435 ! axon extension GO:0048675 16 9 0,000 7,32E-03 0,0204372 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 7,32E-03 0,02041387 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 7,32E-03 0,02039059 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 7,32E-03 0,02036737 ! pentose-phosphate shunt GO:0006098 16 9 0,000 7,32E-03 0,0203442 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 7,32E-03 0,02032108 ! cell proliferation in forebrain GO:0021846 18 9 0,000 7,32E-03 0,02029801 ! neutral lipid catabolic process GO:0046461 14 9 0,000 7,32E-03 0,020275 ! reproductive behavior GO:0019098 22 9 0,000 7,32E-03 0,02025204 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 7,32E-03 0,02022913 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 7,32E-03 0,02020627 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 7,32E-03 0,02018346 ! UTP metabolic process GO:0046051 10 9 0,000 7,32E-03 0,02016071 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 7,32E-03 0,02013801 ! induction of positive chemotaxis GO:0050930 17 9 0,000 7,32E-03 0,02011535 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 7,32E-03 0,02009275 ! artery development GO:0060840 25 9 0,000 7,32E-03 0,0200702 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 7,32E-03 0,0200477 ! regulation of glycolysis GO:0006110 20 9 0,000 7,32E-03 0,02002525 ! cerebral cortex cell migration GO:0021795 18 9 0,000 7,32E-03 0,02000285 ! equilibrioception GO:0050957 20 9 0,000 7,32E-03 0,0199805 ! chemosensory behavior GO:0007635 21 9 0,000 7,32E-03 0,0199582 ! microtubule bundle formation GO:0001578 22 9 0,000 7,32E-03 0,01993595 ! middle ear morphogenesis GO:0042474 14 9 0,000 7,32E-03 0,01991375 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 7,32E-03 0,0198916 ! leukocyte degranulation GO:0043299 16 9 0,000 7,32E-03 0,0198695 ! ganglioside metabolic process GO:0001573 22 9 0,000 7,32E-03 0,01984745 ! negative regulation of endocytosis GO:0045806 12 9 0,000 7,32E-03 0,01982544 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 7,32E-03 0,01980349 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 7,32E-03 0,01978158 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 7,32E-03 0,01975972 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 7,32E-03 0,01973791 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 7,32E-03 0,01971615 ! protein targeting to ER GO:0045047 25 9 0,000 7,32E-03 0,01969444 ! ceramide biosynthetic process GO:0046513 20 9 0,000 7,32E-03 0,01967277 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 7,32E-03 0,01965115 ! T cell selection GO:0045058 27 9 0,000 7,32E-03 0,01962958 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 7,32E-03 0,01960806 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 7,32E-03 0,01958658 ! glycine catabolic process GO:0006546 15 9 0,000 7,32E-03 0,01956515 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 7,32E-03 0,01954377 ! endosome organization GO:0007032 20 9 0,000 7,32E-03 0,01952243 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 7,32E-03 0,01950114 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 7,32E-03 0,0194799 ! regulation of type I interferon production GO:0032479 12 9 0,000 7,32E-03 0,0194587 ! mannose metabolic process GO:0006013 13 9 0,000 7,32E-03 0,01943755 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 7,32E-03 0,01941645 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 7,32E-03 0,01939539 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 7,32E-03 0,01937438 ! Rac protein signal transduction GO:0016601 20 9 0,000 7,32E-03 0,01935341 ! receptor clustering GO:0043113 20 9 0,000 7,32E-03 0,01933249 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 7,32E-03 0,01931161 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 7,32E-03 0,01929078 ! retinol metabolic process GO:0042572 20 9 0,000 7,32E-03 0,01926999 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 7,32E-03 0,01924925 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 7,32E-03 0,01922855 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 7,32E-03 0,01920789 ! macrophage differentiation GO:0030225 15 9 0,000 7,32E-03 0,01918728 ! oligodendrocyte development GO:0014003 11 9 0,000 7,32E-03 0,01916672 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 7,32E-03 0,0191462 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 7,32E-03 0,01912572 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 7,32E-03 0,01910529 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 7,32E-03 0,0190849 ! response to amine stimulus GO:0014075 13 9 0,000 7,32E-03 0,01906455 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 7,32E-03 0,01904425 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 7,32E-03 0,01902399 ! erythrocyte development GO:0048821 17 9 0,000 7,32E-03 0,01900377 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 7,32E-03 0,0189836 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 7,32E-03 0,01896347 ! renal water homeostasis GO:0003091 15 9 0,000 7,32E-03 0,01894338 ! postreplication repair GO:0006301 25 9 0,000 7,32E-03 0,01892333 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 7,32E-03 0,01890333 ! icosanoid secretion GO:0032309 15 9 0,000 7,32E-03 0,01888337 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 7,32E-03 0,01886345 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 7,32E-03 0,01884357 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 7,32E-03 0,01882374 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 7,32E-03 0,01880394 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 7,32E-03 0,01878419 ! sterol catabolic process GO:0016127 14 9 0,000 7,32E-03 0,01876448 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 7,32E-03 0,01874481 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 7,32E-03 0,01872518 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 7,32E-03 0,0187056 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 7,32E-03 0,01868605 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 7,32E-03 0,01866654 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 7,32E-03 0,01864708 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 7,32E-03 0,01862766 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 7,32E-03 0,01860827 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 7,32E-03 0,01858893 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 7,32E-03 0,01856963 ! regulation of synaptogenesis GO:0051963 15 9 0,000 7,32E-03 0,01855036 ! purine base metabolic process GO:0006144 25 9 0,000 7,32E-03 0,01853114 ! pigment granule transport GO:0051904 17 9 0,000 7,32E-03 0,01851196 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 7,32E-03 0,01849281 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 7,32E-03 0,01847371 ! regulation of muscle adaptation GO:0043502 14 9 0,000 7,32E-03 0,01845464 ! regulation of amino acid transport GO:0051955 12 9 0,000 7,32E-03 0,01843562 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 7,32E-03 0,01841663 ! mitochondrion localization GO:0051646 18 9 0,000 7,32E-03 0,01839768 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 8,13E-03 0,02041283 ! regulation of developmental growth GO:0048638 16 10 0,000 8,13E-03 0,02039187 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 8,13E-03 0,02037095 ! autophagic vacuole formation GO:0000045 17 10 0,000 8,13E-03 0,02035008 ! negative regulation of blood pressure GO:0045776 26 10 0,000 8,13E-03 0,02032925 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 8,13E-03 0,02030847 ! associative learning GO:0008306 21 10 0,000 8,13E-03 0,02028772 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 8,13E-03 0,02026702 ! regulation of phosphatase activity GO:0010921 28 10 0,000 8,13E-03 0,02024636 ! phosphate transport GO:0006817 24 10 0,000 8,13E-03 0,02022574 ! cell volume homeostasis GO:0006884 17 10 0,000 8,13E-03 0,02020517 ! CTP metabolic process GO:0046036 11 10 0,000 8,13E-03 0,02018463 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 8,13E-03 0,02016414 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 8,13E-03 0,02014369 ! GTP metabolic process GO:0046039 11 10 0,000 8,13E-03 0,02012328 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 8,13E-03 0,02010291 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 8,13E-03 0,02008259 ! social behavior GO:0035176 29 10 0,000 8,13E-03 0,0200623 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 8,13E-03 0,02004206 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 8,13E-03 0,02002185 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 8,13E-03 0,02000169 ! androgen metabolic process GO:0008209 17 10 0,000 8,13E-03 0,01998157 ! phospholipid efflux GO:0033700 19 10 0,000 8,13E-03 0,01996149 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 8,13E-03 0,01994145 ! bile acid and bile salt transport GO:0015721 15 10 0,000 8,13E-03 0,01992144 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 8,13E-03 0,01990148 ! positive regulation of heart contraction GO:0045823 17 10 0,000 8,13E-03 0,01988156 ! lung alveolus development GO:0048286 26 10 0,000 8,13E-03 0,01986168 ! pathogenesis GO:0009405 17 10 0,000 8,13E-03 0,01984184 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 8,13E-03 0,01982204 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 8,13E-03 0,01980227 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 8,13E-03 0,01978255 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 8,13E-03 0,01976287 ! endoderm development GO:0007492 18 10 0,000 8,13E-03 0,01974322 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 8,13E-03 0,01972361 ! arginine catabolic process GO:0006527 17 10 0,000 8,13E-03 0,01970405 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 8,13E-03 0,01968452 ! proline metabolic process GO:0006560 13 10 0,000 8,13E-03 0,01966503 ! glucan biosynthetic process GO:0009250 14 10 0,000 8,13E-03 0,01964558 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 8,13E-03 0,01962617 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 8,13E-03 0,01960679 ! V(D)J recombination GO:0033151 34 10 0,000 8,13E-03 0,01958746 ! reverse cholesterol transport GO:0043691 19 10 0,000 8,13E-03 0,01956816 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 8,13E-03 0,0195489 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 8,13E-03 0,01952968 ! B cell proliferation GO:0042100 19 10 0,000 8,13E-03 0,01951049 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 8,13E-03 0,01949134 ! regulation of sodium ion transport GO:0002028 26 10 0,000 8,13E-03 0,01947224 ! multicellular organism growth GO:0035264 19 10 0,000 8,13E-03 0,01945316 ! phagocytosis, engulfment GO:0006911 33 10 0,000 8,13E-03 0,01943413 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 8,13E-03 0,01941513 ! ruffle organization GO:0031529 17 10 0,000 8,13E-03 0,01939617 ! epithelial cell development GO:0002064 21 10 0,000 8,13E-03 0,01937725 ! lens development in camera-type eye GO:0002088 17 10 0,000 8,13E-03 0,01935836 ! retinoic acid metabolic process GO:0042573 14 10 0,000 8,13E-03 0,01933951 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 8,13E-03 0,0193207 ! positive regulation of translational initiation GO:0045948 12 10 0,000 8,13E-03 0,01930192 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 8,13E-03 0,01928318 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 8,13E-03 0,01926448 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 8,13E-03 0,01924581 ! motor axon guidance GO:0008045 22 10 0,000 8,13E-03 0,01922718 ! copper ion homeostasis GO:0055070 13 10 0,000 8,13E-03 0,01920859 ! regulation of bone resorption GO:0045124 25 10 0,000 8,13E-03 0,01919003 ! protein heterooligomerization GO:0051291 17 10 0,000 8,13E-03 0,01917151 ! regulation of gliogenesis GO:0014013 23 10 0,000 8,13E-03 0,01915302 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 8,13E-03 0,01913457 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 8,13E-03 0,01911615 ! segment specification GO:0007379 15 10 0,000 8,13E-03 0,01909777 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 8,13E-03 0,01907942 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 8,13E-03 0,01906111 ! blastoderm segmentation GO:0007350 19 10 0,000 8,13E-03 0,01904284 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 8,13E-03 0,0190246 ! response to dsRNA GO:0043331 23 10 0,000 8,13E-03 0,01900639 ! DNA ligation GO:0006266 18 10 0,000 8,13E-03 0,01898822 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 8,13E-03 0,01897009 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 8,13E-03 0,01895198 ! melanosome localization GO:0032400 16 10 0,000 8,13E-03 0,01893392 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 8,13E-03 0,01891589 ! regulation of B cell differentiation GO:0045577 24 10 0,000 8,13E-03 0,01889789 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 8,13E-03 0,01887992 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 8,13E-03 0,01886199 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 8,13E-03 0,0188441 ! leukocyte activation during immune response GO:0002366 15 10 0,000 8,13E-03 0,01882624 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 8,13E-03 0,01880841 ! protein sumoylation GO:0016925 17 10 0,000 8,13E-03 0,01879061 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 8,13E-03 0,01877285 ! hindbrain morphogenesis GO:0021575 19 10 0,000 8,13E-03 0,01875513 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 8,13E-03 0,01873743 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 8,13E-03 0,01871977 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 8,13E-03 0,01870215 ! salivary gland development GO:0007431 28 10 0,000 8,13E-03 0,01868455 ! ubiquinone metabolic process GO:0006743 17 10 0,000 8,13E-03 0,01866699 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 8,13E-03 0,01864946 ! midbrain development GO:0030901 14 10 0,000 8,13E-03 0,01863197 ! musculoskeletal movement GO:0050881 16 10 0,000 8,13E-03 0,01861451 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 8,13E-03 0,01859708 ! methionine biosynthetic process GO:0009086 21 10 0,000 8,13E-03 0,01857968 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 8,13E-03 0,01856232 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 8,13E-03 0,01854499 ! quaternary ammonium group transport GO:0015697 22 10 0,000 8,13E-03 0,01852769 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 8,13E-03 0,01851042 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 8,13E-03 0,01849318 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 8,13E-03 0,01847598 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 8,13E-03 0,01845881 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 8,13E-03 0,01844167 ! establishment of pigment granule localization GO:0051905 18 10 0,000 8,13E-03 0,01842456 ! blastocyst formation GO:0001825 18 10 0,000 8,13E-03 0,01840749 ! regulation of fibrinolysis GO:0051917 20 10 0,000 8,13E-03 0,01839044 ! cerebellar cortex development GO:0021695 16 10 0,000 8,13E-03 0,01837343 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 8,13E-03 0,01835645 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 8,13E-03 0,0183395 ! response to nicotine GO:0035094 20 10 0,000 8,13E-03 0,01832258 ! negative regulation of immune effector process GO:0002698 23 10 0,000 8,13E-03 0,0183057 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 8,13E-03 0,01828884 ! negative regulation of muscle development GO:0048635 27 11 0,000 8,94E-03 0,02009131 ! respiratory burst GO:0045730 17 11 0,000 8,94E-03 0,02007284 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 8,94E-03 0,02005441 ! neuron fate specification GO:0048665 18 11 0,000 8,94E-03 0,02003601 ! telencephalon cell migration GO:0022029 23 11 0,000 8,94E-03 0,02001765 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 8,94E-03 0,01999931 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 8,94E-03 0,01998102 ! synapsis GO:0007129 14 11 0,000 8,94E-03 0,01996275 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 8,94E-03 0,01994452 ! Golgi vesicle budding GO:0048194 26 11 0,000 8,94E-03 0,01992632 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 8,94E-03 0,01990816 ! response to pain GO:0048265 27 11 0,000 8,94E-03 0,01989003 ! detection of mechanical stimulus GO:0050982 22 11 0,000 8,94E-03 0,01987193 ! keratinocyte proliferation GO:0043616 19 11 0,000 8,94E-03 0,01985386 ! blood vessel remodeling GO:0001974 30 11 0,000 8,94E-03 0,01983583 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 8,94E-03 0,01981783 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 8,94E-03 0,01979986 ! bone resorption GO:0045453 16 11 0,000 8,94E-03 0,01978193 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 8,94E-03 0,01976403 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 8,94E-03 0,01974616 ! negative regulation of proteolysis GO:0045861 25 11 0,000 8,94E-03 0,01972832 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 8,94E-03 0,01971052 ! melanocyte differentiation GO:0030318 20 11 0,000 8,94E-03 0,01969274 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 8,94E-03 0,019675 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 8,94E-03 0,01965729 ! L-serine metabolic process GO:0006563 21 11 0,000 8,94E-03 0,01963961 ! regulation of intracellular pH GO:0051453 21 11 0,000 8,94E-03 0,01962197 ! substrate-bound cell migration GO:0006929 14 11 0,000 8,94E-03 0,01960435 ! adult heart development GO:0007512 16 11 0,000 8,94E-03 0,01958677 ! chondrocyte differentiation GO:0002062 27 11 0,000 8,94E-03 0,01956922 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 8,94E-03 0,0195517 ! macroautophagy GO:0016236 19 11 0,000 8,94E-03 0,01953421 ! temperature homeostasis GO:0001659 18 11 0,000 8,94E-03 0,01951676 ! behavioral fear response GO:0001662 27 11 0,000 8,94E-03 0,01949933 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 8,94E-03 0,01948194 ! negative regulation of ossification GO:0030279 27 11 0,000 8,94E-03 0,01946457 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 8,94E-03 0,01944724 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 8,94E-03 0,01942994 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 8,94E-03 0,01941267 ! alpha-beta T cell activation GO:0046631 26 11 0,000 8,94E-03 0,01939543 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 8,94E-03 0,01937822 ! regulation of organ growth GO:0046620 14 11 0,000 8,94E-03 0,01936104 ! pigment granule localization GO:0051875 20 11 0,000 8,94E-03 0,01934389 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 8,94E-03 0,01932677 ! vasoconstriction GO:0042310 20 11 0,000 8,94E-03 0,01930968 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 8,94E-03 0,01929262 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 8,94E-03 0,0192756 ! embryonic axis specification GO:0000578 19 11 0,000 8,94E-03 0,0192586 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 8,94E-03 0,01924163 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 8,94E-03 0,01922469 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 8,94E-03 0,01920778 ! nitric oxide metabolic process GO:0046209 17 11 0,000 8,94E-03 0,01919091 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 8,94E-03 0,01917406 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 8,94E-03 0,01915724 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 8,94E-03 0,01914045 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 8,94E-03 0,01912369 ! prophase GO:0051324 17 11 0,000 8,94E-03 0,01910696 ! neuroblast proliferation GO:0007405 25 11 0,000 8,94E-03 0,01909025 ! nucleosome positioning GO:0016584 15 11 0,000 8,94E-03 0,01907358 ! regulation of isotype switching GO:0045191 24 11 0,000 8,94E-03 0,01905694 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 8,94E-03 0,01904032 ! negative regulation of neurological system process GO:0031645 21 11 0,000 8,94E-03 0,01902374 ! apical protein localization GO:0045176 18 11 0,000 8,94E-03 0,01900718 ! acid secretion GO:0046717 20 11 0,000 8,94E-03 0,01899065 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 8,94E-03 0,01897415 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 8,94E-03 0,01895768 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 8,94E-03 0,01894124 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 8,94E-03 0,01892483 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 8,94E-03 0,01890844 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 8,94E-03 0,01889209 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 8,94E-03 0,01887576 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 8,94E-03 0,01885946 ! oocyte development GO:0048599 20 11 0,000 8,94E-03 0,01884318 ! negative regulation of glucose import GO:0046325 18 11 0,000 8,94E-03 0,01882694 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 8,94E-03 0,01881072 ! embryonic gut development GO:0048566 19 11 0,000 8,94E-03 0,01879454 ! regulation of organic acid transport GO:0032890 19 11 0,000 8,94E-03 0,01877838 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 8,94E-03 0,01876224 ! activation of innate immune response GO:0002218 16 11 0,000 8,94E-03 0,01874614 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 8,94E-03 0,01873006 ! cardiac cell differentiation GO:0035051 36 11 0,000 8,94E-03 0,01871401 ! lysogeny GO:0030069 22 11 0,000 8,94E-03 0,01869799 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 8,94E-03 0,01868199 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 8,94E-03 0,01866603 ! sequestering of metal ion GO:0051238 15 11 0,000 8,94E-03 0,01865009 ! regulation of embryonic development GO:0045995 35 11 0,000 8,94E-03 0,01863417 ! nucleus localization GO:0051647 22 11 0,000 8,94E-03 0,01861829 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 9,748E-03 0,02028557 ! positive regulation of blood pressure GO:0045777 18 12 0,000 9,748E-03 0,02026831 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 9,748E-03 0,02025107 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 9,748E-03 0,02023387 ! virus-host interaction GO:0019048 30 12 0,000 9,748E-03 0,02021669 ! regulation of B cell proliferation GO:0030888 22 12 0,000 9,748E-03 0,02019955 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 9,748E-03 0,02018243 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 9,748E-03 0,02016534 ! protein complex disassembly GO:0043241 28 12 0,000 9,748E-03 0,02014828 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 9,748E-03 0,02013125 ! regulation of cell projection assembly GO:0060491 33 12 0,000 9,748E-03 0,02011424 ! hippocampus development GO:0021766 29 12 0,000 9,748E-03 0,02009727 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 9,748E-03 0,02008032 ! cytokine biosynthetic process GO:0042089 23 12 0,000 9,748E-03 0,02006341 ! T cell proliferation GO:0042098 32 12 0,000 9,748E-03 0,02004652 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 9,748E-03 0,02002966 ! regulation of exit from mitosis GO:0007096 19 12 0,000 9,748E-03 0,02001283 ! ventral spinal cord development GO:0021517 25 12 0,000 9,748E-03 0,01999602 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 9,748E-03 0,01997925 ! drug transport GO:0015893 16 12 0,000 9,748E-03 0,0199625 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 9,748E-03 0,01994578 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 9,748E-03 0,01992909 ! tyrosine metabolic process GO:0006570 19 12 0,000 9,748E-03 0,01991243 ! polyamine metabolic process GO:0006595 18 12 0,000 9,748E-03 0,01989579 ! focal adhesion formation GO:0048041 37 12 0,000 9,748E-03 0,01987919 ! mitotic spindle organization GO:0007052 23 12 0,000 9,748E-03 0,01986261 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 9,748E-03 0,01984605 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 9,748E-03 0,01982953 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 9,748E-03 0,01981303 ! lipid digestion GO:0044241 21 12 0,000 9,748E-03 0,01979656 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 9,748E-03 0,01978012 ! entry into host cell GO:0030260 34 12 0,000 9,748E-03 0,0197637 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 9,748E-03 0,01974732 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 9,748E-03 0,01973096 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 9,748E-03 0,01971462 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 9,748E-03 0,01969832 ! protein targeting to peroxisome GO:0006625 27 12 0,000 9,748E-03 0,01968204 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 9,748E-03 0,01966578 ! regulation of phagocytosis GO:0050764 17 12 0,000 9,748E-03 0,01964956 ! snRNA metabolic process GO:0016073 30 12 0,000 9,748E-03 0,01963336 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 9,748E-03 0,01961719 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 9,748E-03 0,01960104 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 9,748E-03 0,01958492 ! cranial nerve development GO:0021545 23 12 0,000 9,748E-03 0,01956883 ! fucose catabolic process GO:0019317 25 12 0,000 9,748E-03 0,01955276 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 9,748E-03 0,01953672 ! histone acetylation GO:0016573 27 12 0,000 9,748E-03 0,01952071 ! mRNA polyadenylation GO:0006378 24 12 0,000 9,748E-03 0,01950472 ! autonomic nervous system development GO:0048483 24 12 0,000 9,748E-03 0,01948876 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 9,748E-03 0,01947282 ! zymogen activation GO:0031638 18 12 0,000 9,748E-03 0,01945691 ! peptidyl-lysine modification GO:0018205 21 12 0,000 9,748E-03 0,01944103 ! T cell homeostasis GO:0043029 28 12 0,000 9,748E-03 0,01942517 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 9,748E-03 0,01940934 ! glutathione biosynthetic process GO:0006750 15 12 0,000 9,748E-03 0,01939354 ! regulation of leukocyte migration GO:0002685 29 12 0,000 9,748E-03 0,01937776 ! oocyte differentiation GO:0009994 21 12 0,000 9,748E-03 0,019362 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 9,748E-03 0,01934627 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 9,748E-03 0,01933057 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 9,748E-03 0,01931489 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 9,748E-03 0,01929924 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 9,748E-03 0,01928361 ! defense response to fungus GO:0050832 15 12 0,000 9,748E-03 0,01926801 ! embryonic placenta development GO:0001892 21 12 0,000 9,748E-03 0,01925244 ! lamellipodium assembly GO:0030032 24 12 0,000 9,748E-03 0,01923689 ! response to cold GO:0009409 17 12 0,000 9,748E-03 0,01922136 ! establishment of cell polarity GO:0030010 21 12 0,000 9,748E-03 0,01920586 ! regulation of synapse organization GO:0050807 18 12 0,000 9,748E-03 0,01919038 ! localization within membrane GO:0051668 26 12 0,000 9,748E-03 0,01917493 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01055658 0,02074796 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01055658 0,02073129 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01055658 0,02071463 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01055658 0,02069801 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01055658 0,02068141 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01055658 0,02066484 ! peroxisomal transport GO:0043574 28 13 0,000 0,01055658 0,02064829 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01055658 0,02063178 ! cartilage condensation GO:0001502 22 13 0,000 0,01055658 0,02061528 ! organelle fusion GO:0048284 36 13 0,000 0,01055658 0,02059882 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01055658 0,02058238 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01055658 0,02056596 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01055658 0,02054958 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01055658 0,02053322 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01055658 0,02051688 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01055658 0,02050057 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01055658 0,02048429 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01055658 0,02046803 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01055658 0,0204518 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01055658 0,02043559 ! methionine metabolic process GO:0006555 31 13 0,000 0,01055658 0,02041941 ! plasma membrane organization GO:0007009 27 13 0,000 0,01055658 0,02040326 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01055658 0,02038713 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01055658 0,02037103 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01055658 0,02035495 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01055658 0,0203389 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01055658 0,02032287 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01055658 0,02030687 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,01055658 0,02029089 ! exocrine system development GO:0035272 34 13 0,000 0,01055658 0,02027494 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01055658 0,02025901 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01055658 0,02024311 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01055658 0,02022723 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01055658 0,02021138 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01055658 0,02019555 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01055658 0,02017975 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01055658 0,02016397 ! protein homotetramerization GO:0051289 24 13 0,000 0,01055658 0,02014822 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01055658 0,02013249 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01055658 0,02011679 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01055658 0,02010111 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01055658 0,02008545 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01055658 0,02006982 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01055658 0,02005421 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01055658 0,02003863 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01055658 0,02002307 ! histone methylation GO:0016571 29 13 0,000 0,01055658 0,02000754 ! chromatin silencing GO:0006342 29 13 0,000 0,01055658 0,01999203 ! gland morphogenesis GO:0022612 31 13 0,000 0,01055658 0,01997654 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01055658 0,01996108 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01055658 0,01994565 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01055658 0,01993023 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01055658 0,01991484 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01055658 0,01989947 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01055658 0,01988413 ! spleen development GO:0048536 24 13 0,000 0,01055658 0,01986881 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01055658 0,01985352 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01055658 0,01983825 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01055658 0,019823 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01055658 0,01980777 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01055658 0,01979257 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01055658 0,01977739 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01055658 0,01976224 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01055658 0,01974711 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01055658 0,019732 ! insulin secretion GO:0030073 24 13 0,000 0,01055658 0,01971691 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01055658 0,01970185 ! acrosome reaction GO:0007340 19 13 0,000 0,01055658 0,01968681 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01055658 0,01967179 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01055658 0,0196568 ! rRNA transcription GO:0009303 28 14 0,000 0,01136415 0,02114442 ! regulation of S phase GO:0033261 26 14 0,000 0,01136415 0,02112833 ! water transport GO:0006833 21 14 0,000 0,01136415 0,02111226 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01136415 0,02109622 ! non-recombinational repair GO:0000726 29 14 0,000 0,01136415 0,0210802 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01136415 0,0210642 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01136415 0,02104823 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01136415 0,02103229 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01136415 0,02101637 ! lipid localization GO:0010876 32 14 0,000 0,01136415 0,02100047 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01136415 0,02098459 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01136415 0,02096875 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01136415 0,02095292 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01136415 0,02093712 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01136415 0,02092134 ! arginine metabolic process GO:0006525 21 14 0,000 0,01136415 0,02090559 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01136415 0,02088986 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01136415 0,02087415 ! regulation of heart rate GO:0002027 25 14 0,000 0,01136415 0,02085847 ! fear response GO:0042596 34 14 0,000 0,01136415 0,02084281 ! organic alcohol transport GO:0015850 29 14 0,000 0,01136415 0,02082717 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01136415 0,02081156 ! embryo implantation GO:0007566 30 14 0,000 0,01136415 0,02079597 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01136415 0,0207804 ! bone mineralization GO:0030282 18 14 0,000 0,01136415 0,02076486 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01136415 0,02074934 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01136415 0,02073385 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01136415 0,02071837 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01136415 0,02070292 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01136415 0,0206875 ! ribosome assembly GO:0042255 18 14 0,000 0,01136415 0,02067209 ! cerebellum development GO:0021549 23 14 0,000 0,01136415 0,02065671 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01136415 0,02064135 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01136415 0,02062602 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01136415 0,0206107 ! response to gamma radiation GO:0010332 30 14 0,000 0,01136415 0,02059541 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01136415 0,02058015 ! NADP metabolic process GO:0006739 24 14 0,000 0,01136415 0,0205649 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01136415 0,02054968 ! oxygen transport GO:0015671 22 14 0,000 0,01136415 0,02053448 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01136415 0,0205193 ! male genitalia development GO:0030539 26 14 0,000 0,01136415 0,02050415 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01136415 0,02048902 ! regulation of axon extension GO:0030516 43 14 0,000 0,01136415 0,02047391 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01136415 0,02045882 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01136415 0,02044375 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01136415 0,02042871 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01217109 0,02186321 ! lactation GO:0007595 30 15 0,000 0,01217109 0,02184714 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01217109 0,0218311 ! reproductive cellular process GO:0048610 22 15 0,000 0,01217109 0,02181509 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01217109 0,02179909 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01217109 0,02178312 ! superoxide anion generation GO:0042554 22 15 0,000 0,01217109 0,02176718 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01217109 0,02175125 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01217109 0,02173535 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01217109 0,02171948 ! copper ion transport GO:0006825 22 15 0,000 0,01217109 0,02170362 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01217109 0,02168779 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01217109 0,02167199 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01217109 0,0216562 ! sulfate transport GO:0008272 27 15 0,000 0,01217109 0,02164044 ! response to cAMP GO:0051591 25 15 0,000 0,01217109 0,0216247 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01217109 0,02160899 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01217109 0,02159329 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01217109 0,02157762 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01217109 0,02156198 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01217109 0,02154635 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01217109 0,02153075 ! vesicle coating GO:0006901 38 15 0,000 0,01217109 0,02151517 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01217109 0,02149961 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01217109 0,02148408 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01217109 0,02146857 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01217109 0,02145308 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01217109 0,02143761 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01217109 0,02142216 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01217109 0,02140674 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01217109 0,02139134 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01217109 0,02137596 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01217109 0,02136061 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01217109 0,02134527 ! histone deacetylation GO:0016575 24 15 0,000 0,01217109 0,02132996 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01217109 0,02131467 ! water homeostasis GO:0030104 28 15 0,000 0,01217109 0,0212994 ! cofactor transport GO:0051181 30 15 0,000 0,01217109 0,02128415 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01217109 0,02126893 ! muscle maintenance GO:0046716 26 15 0,000 0,01217109 0,02125373 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01217109 0,02123855 ! intestinal absorption GO:0050892 31 15 0,000 0,01217109 0,02122339 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01217109 0,02120825 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01217109 0,02119313 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01217109 0,02117804 ! cell killing GO:0001906 32 15 0,000 0,01217109 0,02116296 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01217109 0,02114791 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01217109 0,02113288 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01217109 0,02111787 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01217109 0,02110288 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01217109 0,02108792 ! actin filament polymerization GO:0030041 27 15 0,000 0,01217109 0,02107297 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01217109 0,02105805 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,01297739 0,02243719 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01297739 0,02242133 ! positive regulation of cell size GO:0045793 29 16 0,000 0,01297739 0,02240548 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01297739 0,02238966 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01297739 0,02237386 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01297739 0,02235808 ! bone remodeling GO:0046849 28 16 0,000 0,01297739 0,02234232 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01297739 0,02232659 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01297739 0,02231088 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01297739 0,02229519 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01297739 0,02227952 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01297739 0,02226387 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01297739 0,02224825 ! startle response GO:0001964 28 16 0,000 0,01297739 0,02223265 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01297739 0,02221707 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01297739 0,02220151 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01297739 0,02218597 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01297739 0,02217046 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01297739 0,02215497 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01297739 0,02213949 ! pituitary gland development GO:0021983 30 16 0,000 0,01297739 0,02212404 ! response to osmotic stress GO:0006970 27 16 0,000 0,01297739 0,02210862 ! lysosomal transport GO:0007041 31 16 0,000 0,01297739 0,02209321 ! fructose metabolic process GO:0006000 25 16 0,000 0,01297739 0,02207782 ! L-amino acid transport GO:0015807 33 16 0,000 0,01297739 0,02206246 ! stem cell development GO:0048864 46 16 0,000 0,01297739 0,02204712 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01297739 0,0220318 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01297739 0,0220165 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01297739 0,02200122 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01297739 0,02198596 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01297739 0,02197072 ! axon cargo transport GO:0008088 46 16 0,000 0,01297739 0,02195551 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01297739 0,02194032 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01297739 0,02192514 ! DNA replication initiation GO:0006270 28 16 0,000 0,01297739 0,02190999 ! neuron recognition GO:0008038 40 16 0,000 0,01297739 0,02189486 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01297739 0,02187975 ! tissue regeneration GO:0042246 27 16 0,000 0,01297739 0,02186466 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01297739 0,02184959 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01297739 0,02183454 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01297739 0,02181952 ! biomineral formation GO:0031214 22 16 0,000 0,01297739 0,02180451 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01297739 0,02178952 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01297739 0,02177456 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01297739 0,02175961 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01297739 0,02174469 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01297739 0,02172978 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01297739 0,0217149 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01297739 0,02170004 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01297739 0,0216852 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01297739 0,02167037 ! peptide hormone processing GO:0016486 27 16 0,000 0,01297739 0,02165557 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,01378305 0,0229843 ! metencephalon development GO:0022037 32 17 0,000 0,01378305 0,02296862 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,01378305 0,02295296 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,01378305 0,02293733 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,01378305 0,02292171 ! signal complex assembly GO:0007172 47 17 0,000 0,01378305 0,02290612 ! filopodium assembly GO:0046847 42 17 0,000 0,01378305 0,02289055 ! endothelial cell migration GO:0043542 31 17 0,000 0,01378305 0,022875 ! gene silencing by RNA GO:0031047 38 17 0,000 0,01378305 0,02285947 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,01378305 0,02284396 ! glial cell development GO:0021782 28 17 0,000 0,01378305 0,02282847 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,01378305 0,022813 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,01378305 0,02279756 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,01378305 0,02278213 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,01378305 0,02276673 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,01378305 0,02275135 ! myoblast differentiation GO:0045445 50 17 0,000 0,01378305 0,02273599 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,01378305 0,02272064 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,01378305 0,02270532 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,01378305 0,02269002 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,01378305 0,02267474 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,01378305 0,02265948 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,01378305 0,02264425 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,01378305 0,02262903 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,01378305 0,02261383 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,01378305 0,02259865 ! membrane budding GO:0006900 42 17 0,000 0,01378305 0,0225835 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,01378305 0,02256836 ! regulation of protein binding GO:0043393 33 17 0,000 0,01378305 0,02255324 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,01378305 0,02253815 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,01378305 0,02252307 ! genitalia development GO:0048806 32 17 0,000 0,01378305 0,02250802 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,01378305 0,02249298 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,01378305 0,02247797 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,01378305 0,02246297 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,01378305 0,022448 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,01378305 0,02243304 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,01378305 0,02241811 ! steroid catabolic process GO:0006706 34 17 0,000 0,01378305 0,02240319 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,01378305 0,02238829 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,01378305 0,02237342 ! gas transport GO:0015669 26 17 0,000 0,01378305 0,02235856 ! organic cation transport GO:0015695 32 17 0,000 0,01378305 0,02234373 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,01378305 0,02232891 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,01378305 0,02231411 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,01458808 0,02360178 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,01458808 0,02358616 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,01458808 0,02357056 ! limbic system development GO:0021761 40 18 0,000 0,01458808 0,02355498 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01458808 0,02353942 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,01458808 0,02352388 ! adult walking behavior GO:0007628 36 18 0,000 0,01458808 0,02350837 ! patterning of blood vessels GO:0001569 43 18 0,000 0,01458808 0,02349287 ! heart looping GO:0001947 34 18 0,000 0,01458808 0,02347739 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,01458808 0,02346194 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,01458808 0,0234465 ! centrosome cycle GO:0007098 26 18 0,000 0,01458808 0,02343109 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,01458808 0,02341569 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,01458808 0,02340032 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,01458808 0,02338496 ! glycine metabolic process GO:0006544 30 18 0,000 0,01458808 0,02336963 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01458808 0,02335431 ! response to retinoic acid GO:0032526 31 18 0,000 0,01458808 0,02333902 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,01458808 0,02332374 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,01458808 0,02330849 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,01458808 0,02329326 ! DNA integration GO:0015074 32 18 0,000 0,01458808 0,02327804 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,01458808 0,02326285 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,01458808 0,02324767 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,01458808 0,02323252 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,01458808 0,02321738 ! neural crest cell migration GO:0001755 41 18 0,000 0,01458808 0,02320227 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,01458808 0,02318717 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,01458808 0,02317209 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,01458808 0,02315704 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,01458808 0,023142 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,01458808 0,02312698 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,01458808 0,02311199 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,01458808 0,02309701 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,01458808 0,02308205 ! detection of bacterium GO:0016045 22 18 0,000 0,01458808 0,02306711 ! nerve development GO:0021675 34 18 0,000 0,01458808 0,02305219 ! defense response to virus GO:0051607 43 18 0,000 0,01458808 0,02303729 ! microspike assembly GO:0030035 46 18 0,000 0,01458808 0,0230224 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,01458808 0,02300754 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,01458808 0,0229927 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,01539248 0,02424489 ! positive regulation of translation GO:0045727 31 19 0,000 0,01539248 0,02422927 ! negative regulation of defense response GO:0031348 27 19 0,000 0,01539248 0,02421366 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,01539248 0,02419808 ! neuron maturation GO:0042551 46 19 0,000 0,01539248 0,02418252 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,01539248 0,02416698 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,01539248 0,02415146 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,01539248 0,02413596 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,01539248 0,02412047 ! inositol metabolic process GO:0006020 33 19 0,000 0,01539248 0,02410501 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01539248 0,02408957 ! memory GO:0007613 34 19 0,000 0,01539248 0,02407415 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,01539248 0,02405875 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,01539248 0,02404336 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,01539248 0,024028 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,01539248 0,02401266 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,01539248 0,02399733 ! cerebral cortex development GO:0021987 40 19 0,000 0,01539248 0,02398203 ! pigmentation during development GO:0048066 42 19 0,000 0,01539248 0,02396674 ! response to vitamin A GO:0033189 32 19 0,000 0,01539248 0,02395148 ! heme metabolic process GO:0042168 40 19 0,000 0,01539248 0,02393623 ! neuromuscular junction development GO:0007528 43 19 0,000 0,01539248 0,023921 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,01539248 0,0239058 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,01539248 0,02389061 ! response to fungus GO:0009620 26 19 0,000 0,01539248 0,02387544 ! peptide cross-linking GO:0018149 39 19 0,000 0,01539248 0,02386029 ! protein export from nucleus GO:0006611 40 19 0,000 0,01539248 0,02384516 ! heart process GO:0003015 32 19 0,000 0,01539248 0,02383005 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,01539248 0,02381496 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,01539248 0,02379989 ! cellular pigmentation GO:0033059 37 19 0,000 0,01539248 0,02378483 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,01539248 0,0237698 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,01539248 0,02375478 ! vitamin transport GO:0051180 31 19 0,000 0,01539248 0,02373979 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,01539248 0,02372481 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,01539248 0,02370985 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,01539248 0,02369491 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,01539248 0,02367999 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,01539248 0,02366508 ! cilium assembly GO:0042384 38 19 0,000 0,01539248 0,0236502 ! peptide hormone secretion GO:0030072 32 19 0,000 0,01539248 0,02363534 ! protein secretion GO:0009306 45 20 0,000 0,01619624 0,0248539 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,01619624 0,0248383 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,01619624 0,02482272 ! positive regulation of ossification GO:0045778 50 20 0,000 0,01619624 0,02480715 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,01619624 0,02479161 ! skin development GO:0043588 42 20 0,000 0,01619624 0,02477609 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,01619624 0,02476058 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,01619624 0,0247451 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,01619624 0,02472963 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,01619624 0,02471418 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,01619624 0,02469876 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,01619624 0,02468335 ! response to vitamin GO:0033273 36 20 0,000 0,01619624 0,02466796 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,01619624 0,02465259 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,01619624 0,02463724 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,01619624 0,02462191 ! bile acid metabolic process GO:0008206 34 20 0,000 0,01619624 0,0246066 ! response to alkaloid GO:0043279 38 20 0,000 0,01619624 0,0245913 ! retinoid metabolic process GO:0001523 34 20 0,000 0,01619624 0,02457603 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,01619624 0,02456077 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,01619624 0,02454554 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,01619624 0,02453032 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,01619624 0,02451512 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,01619624 0,02449994 ! actin filament bundle formation GO:0051017 47 20 0,000 0,01619624 0,02448478 ! body fluid secretion GO:0007589 33 20 0,000 0,01619624 0,02446964 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,01619624 0,02445452 ! peptide secretion GO:0002790 38 20 0,000 0,01619624 0,02443941 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,01619624 0,02442433 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,01619624 0,02440926 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,01619624 0,02439421 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,01619624 0,02437918 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,01619624 0,02436417 ! cell-cell junction organization GO:0045216 43 20 0,000 0,01619624 0,02434917 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,01619624 0,0243342 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,01619624 0,02431924 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,01619624 0,0243043 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,01619624 0,02428939 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,01619624 0,02427448 ! regulation of glucose import GO:0046324 30 20 0,000 0,01619624 0,0242596 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,01619624 0,02424474 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,01619624 0,02422989 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,01619624 0,02421506 ! negative regulation of translation GO:0017148 32 20 0,000 0,01619624 0,02420025 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,01619624 0,02418546 ! regulation of cell killing GO:0031341 46 21 0,000 0,01699937 0,02536924 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,01699937 0,02535375 ! hormone secretion GO:0046879 39 21 0,000 0,01699937 0,02533829 ! lipid phosphorylation GO:0046834 43 21 0,000 0,01699937 0,02532283 ! cAMP metabolic process GO:0046058 41 21 0,000 0,01699937 0,0253074 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,01699937 0,02529199 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,01699937 0,0252766 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,01699937 0,02526122 ! ovarian follicle development GO:0001541 39 21 0,000 0,01699937 0,02524587 ! smooth muscle contraction GO:0006939 48 21 0,000 0,01699937 0,02523053 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,01699937 0,02521521 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,01699937 0,02519991 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,01699937 0,02518463 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,01699937 0,02516936 ! plasma membrane fusion GO:0045026 33 21 0,000 0,01699937 0,02515412 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,01699937 0,02513889 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,01699937 0,02512368 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,01699937 0,02510849 ! sensory perception of pain GO:0019233 33 21 0,000 0,01699937 0,02509332 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,01699937 0,02507817 ! diencephalon development GO:0021536 36 21 0,000 0,01699937 0,02506304 ! collagen fibril organization GO:0030199 62 21 0,000 0,01699937 0,02504792 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,01699937 0,02503282 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,01699937 0,02501774 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,01699937 0,02500268 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,01699937 0,02498763 ! collagen catabolic process GO:0030574 29 21 0,000 0,01699937 0,02497261 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,01699937 0,0249576 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,01699937 0,02494261 ! sperm-egg recognition GO:0035036 23 21 0,000 0,01699937 0,02492764 ! actin filament-based movement GO:0030048 47 21 0,000 0,01699937 0,02491269 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,01699937 0,02489775 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,01780186 0,02605749 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,01780186 0,02604188 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,01780186 0,0260263 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,01780186 0,02601073 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,01780186 0,02599518 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,01780186 0,02597966 ! microtubule-based transport GO:0010970 59 22 0,000 0,01780186 0,02596415 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,01780186 0,02594865 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,01780186 0,02593318 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,01780186 0,02591773 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,01780186 0,02590229 ! cellular response to starvation GO:0009267 37 22 0,000 0,01780186 0,02588687 ! vacuolar transport GO:0007034 41 22 0,000 0,01780186 0,02587147 ! central nervous system neuron development GO:0021954 47 22 0,000 0,01780186 0,02585609 ! fucose metabolic process GO:0006004 44 22 0,000 0,01780186 0,02584073 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,01780186 0,02582538 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,01780186 0,02581006 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,01780186 0,02579475 ! stem cell differentiation GO:0048863 57 22 0,000 0,01780186 0,02577946 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,01780186 0,02576418 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,01780186 0,02574893 ! cytolysis GO:0019835 27 22 0,000 0,01780186 0,02573369 ! renal system process GO:0003014 42 22 0,000 0,01780186 0,02571848 ! vasodilation GO:0042311 40 22 0,000 0,01780186 0,02570328 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,01780186 0,02568809 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,01780186 0,02567293 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,01780186 0,02565778 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,01780186 0,02564266 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,01780186 0,02562754 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,01780186 0,02561245 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,01780186 0,02559738 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,01780186 0,02558232 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,01780186 0,02556728 ! sarcomere organization GO:0045214 32 22 0,000 0,01780186 0,02555226 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,01780186 0,02553725 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,01780186 0,02552227 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,01780186 0,0255073 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,01780186 0,02549235 ! gut development GO:0048565 44 22 0,000 0,01780186 0,02547741 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,01780186 0,0254625 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,01780186 0,0254476 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,01780186 0,02543272 ! protein stabilization GO:0050821 41 22 0,000 0,01780186 0,02541785 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,01860372 0,02654725 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,01860372 0,02653175 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,01860372 0,02651627 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,01860372 0,02650081 ! gluconeogenesis GO:0006094 38 23 0,000 0,01860372 0,02648537 ! glycerol metabolic process GO:0006071 40 23 0,000 0,01860372 0,02646994 ! viral genome replication GO:0019079 44 23 0,000 0,01860372 0,02645454 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,01860372 0,02643915 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,01860372 0,02642377 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,01860372 0,02640842 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,01860372 0,02639309 ! regeneration GO:0031099 42 23 0,000 0,01860372 0,02637777 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,01860372 0,02636247 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,01860372 0,02634718 ! response to ethanol GO:0045471 47 23 0,000 0,01860372 0,02633192 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,01860372 0,02631667 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,01860372 0,02630144 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,01860372 0,02628623 ! peroxisome organization GO:0007031 43 23 0,000 0,01860372 0,02627104 ! lysosome organization GO:0007040 47 23 0,000 0,01860372 0,02625586 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,01860372 0,0262407 ! vesicle targeting GO:0006903 49 23 0,000 0,01860372 0,02622556 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,01860372 0,02621043 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,01860372 0,02619533 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,01860372 0,02618024 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,01860372 0,02616517 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,01860372 0,02615011 ! DNA modification GO:0006304 36 23 0,000 0,01860372 0,02613507 ! fatty acid transport GO:0015908 47 23 0,000 0,01860372 0,02612005 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,01860372 0,02610505 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,01860372 0,02609006 ! hormone transport GO:0009914 41 23 0,000 0,01860372 0,0260751 ! cell-cell recognition GO:0009988 28 23 0,000 0,01860372 0,02606014 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,01860372 0,02604521 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,01860372 0,02603029 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,01860372 0,02601539 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,01940495 0,02712031 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,01940495 0,0271048 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,01940495 0,02708931 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,01940495 0,02707384 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,01940495 0,02705839 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,01940495 0,02704295 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,01940495 0,02702754 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,01940495 0,02701214 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,01940495 0,02699675 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,01940495 0,02698139 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,01940495 0,02696604 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,01940495 0,02695071 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,01940495 0,0269354 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,01940495 0,0269201 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,01940495 0,02690482 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,01940495 0,02688956 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,01940495 0,02687432 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,01940495 0,02685909 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,01940495 0,02684388 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,01940495 0,02682869 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,01940495 0,02681352 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,01940495 0,02679836 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,01940495 0,02678322 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,01940495 0,0267681 ! membrane depolarization GO:0051899 45 24 0,000 0,01940495 0,02675299 ! pallium development GO:0021543 56 24 0,000 0,01940495 0,0267379 ! oogenesis GO:0048477 44 24 0,000 0,01940495 0,02672283 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,01940495 0,02670777 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,01940495 0,02669274 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,01940495 0,02667771 ! platelet activation GO:0030168 41 24 0,000 0,01940495 0,02666271 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,01940495 0,02664772 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,01940495 0,02663275 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,01940495 0,0266178 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,01940495 0,02660286 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,01940495 0,02658794 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,01940495 0,02657304 ! regulation of amine transport GO:0051952 41 24 0,000 0,01940495 0,02655815 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,01940495 0,02654328 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02020555 0,02762292 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,02020555 0,02760747 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02020555 0,02759204 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02020555 0,02757663 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02020555 0,02756123 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02020555 0,02754585 ! phototransduction GO:0007602 37 25 0,000 0,02020555 0,02753049 ! keratinization GO:0031424 37 25 0,000 0,02020555 0,02751514 ! vasculogenesis GO:0001570 49 25 0,000 0,02020555 0,02749981 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,02020555 0,0274845 ! vacuole organization GO:0007033 49 25 0,000 0,02020555 0,0274692 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02020555 0,02745393 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02020555 0,02743867 ! receptor metabolic process GO:0043112 53 25 0,000 0,02020555 0,02742342 ! chromosome condensation GO:0030261 48 25 0,000 0,02020555 0,0274082 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02020555 0,02739299 ! regulation of behavior GO:0050795 48 25 0,000 0,02020555 0,02737779 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02020555 0,02736262 ! interaction with host GO:0051701 66 25 0,000 0,02020555 0,02734746 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02020555 0,02733231 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02020555 0,02731719 ! immunoglobulin production GO:0002377 62 25 0,000 0,02020555 0,02730208 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02020555 0,02728699 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,02020555 0,02727191 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02020555 0,02725685 ! liver development GO:0001889 55 25 0,000 0,02020555 0,02724181 ! protein tetramerization GO:0051262 57 25 0,000 0,02020555 0,02722678 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,02100552 0,02828913 ! myelination GO:0042552 50 26 0,000 0,02100552 0,02827354 ! initiation of viral infection GO:0019059 60 26 0,000 0,02100552 0,02825797 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,02100552 0,02824242 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,02100552 0,02822689 ! molting cycle process GO:0022404 52 26 0,000 0,02100552 0,02821137 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,02100552 0,02819587 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,02100552 0,02818038 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,02100552 0,02816492 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,02100552 0,02814947 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,02100552 0,02813404 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,02100552 0,02811862 ! digestive system process GO:0022600 49 26 0,000 0,02100552 0,02810322 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,02100552 0,02808784 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,02100552 0,02807247 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,02100552 0,02805712 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,02100552 0,02804179 ! osteoblast differentiation GO:0001649 63 26 0,000 0,02100552 0,02802648 ! neural crest cell development GO:0014032 59 26 0,000 0,02100552 0,02801118 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,02100552 0,0279959 ! negative regulation of cell development GO:0010721 83 26 0,000 0,02100552 0,02798063 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,02100552 0,02796538 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,02100552 0,02795015 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,02100552 0,02793494 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,02100552 0,02791974 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,02100552 0,02790456 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,02100552 0,02788939 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,02100552 0,02787424 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,02100552 0,02785911 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,02100552 0,02784399 ! blastocyst development GO:0001824 50 26 0,000 0,02100552 0,02782889 ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,02100552 0,02781381 ! neural tube closure GO:0001843 58 26 0,000 0,02100552 0,02779874 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,02100552 0,02778369 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,02100552 0,02776866 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02180485 0,02880977 ! embryonic pattern specification GO:0009880 49 27 0,000 0,02180485 0,02879419 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,02180485 0,02877864 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,02180485 0,0287631 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,02180485 0,02874758 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,02180485 0,02873207 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,02180485 0,02871658 ! iron ion transport GO:0006826 65 27 0,000 0,02180485 0,02870111 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,02180485 0,02868565 ! superoxide metabolic process GO:0006801 41 27 0,000 0,02180485 0,02867021 ! tube lumen formation GO:0035148 59 27 0,000 0,02180485 0,02865479 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,02180485 0,02863939 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,02180485 0,028624 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,02180485 0,02860862 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,02180485 0,02859327 ! response to starvation GO:0042594 47 27 0,000 0,02180485 0,02857793 ! response to toxin GO:0009636 49 27 0,000 0,02180485 0,02856261 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,02180485 0,0285473 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,02180485 0,02853201 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,02180485 0,02851673 ! leukocyte proliferation GO:0070661 59 27 0,000 0,02180485 0,02850148 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,02180485 0,02848624 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,02260356 0,0295139 ! neuron fate commitment GO:0048663 52 28 0,000 0,02260356 0,02949813 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,02260356 0,02948238 ! protein amino acid acylation GO:0043543 59 28 0,000 0,02260356 0,02946665 ! vesicle docking GO:0048278 55 28 0,000 0,02260356 0,02945093 ! circadian rhythm GO:0007623 56 28 0,000 0,02260356 0,02943523 ! dendrite development GO:0016358 67 28 0,000 0,02260356 0,02941955 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,02260356 0,02940389 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,02260356 0,02938824 ! sperm motility GO:0030317 37 28 0,000 0,02260356 0,02937261 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,02260356 0,02935699 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,02260356 0,02934139 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,02260356 0,02932581 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,02260356 0,02931024 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,02260356 0,02929469 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,02260356 0,02927916 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,02260356 0,02926365 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,02260356 0,02924815 ! glutathione metabolic process GO:0006749 42 28 0,000 0,02260356 0,02923266 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,02260356 0,0292172 ! lipid oxidation GO:0034440 48 28 0,000 0,02260356 0,02920174 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,02260356 0,02918631 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,02340164 0,03020085 ! translational initiation GO:0006413 66 29 0,000 0,02340164 0,0301849 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,02340164 0,03016897 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,02340164 0,03015306 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,02340164 0,03013716 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,02340164 0,03012129 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,02340164 0,03010542 ! primary neural tube formation GO:0014020 61 29 0,000 0,02340164 0,03008958 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,02340164 0,03007375 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,02340164 0,03005794 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,02340164 0,03004214 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,02340164 0,03002637 ! somitogenesis GO:0001756 52 29 0,000 0,02340164 0,0300106 ! synaptogenesis GO:0007416 46 29 0,000 0,02340164 0,02999486 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,02340164 0,02997913 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,02340164 0,02996342 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,02340164 0,02994772 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,02419909 0,03095202 ! phenol metabolic process GO:0018958 56 30 0,000 0,02419909 0,03093583 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,02419909 0,03091965 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,02419909 0,03090348 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,02419909 0,03088734 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,02419909 0,03087121 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,02419909 0,0308551 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,02419909 0,030839 ! acute-phase response GO:0006953 50 30 0,000 0,02419909 0,03082292 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,02419909 0,03080686 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,02419909 0,03079082 ! myofibril assembly GO:0030239 50 30 0,000 0,02419909 0,03077479 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,02419909 0,03075878 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,02419909 0,03074278 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,02419909 0,0307268 ! cell fate determination GO:0001709 64 30 0,000 0,02419909 0,03071084 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,02419909 0,03069489 ! phospholipid transport GO:0015914 65 30 0,000 0,02419909 0,03067897 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,02419909 0,03066305 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,02419909 0,03064716 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,02419909 0,03063128 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,02419909 0,03061541 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,02419909 0,03059957 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,02419909 0,03058374 ! regulation of coagulation GO:0050818 52 30 0,000 0,02419909 0,03056792 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,0249959 0,03155814 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,0249959 0,03154184 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,0249959 0,03152555 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,0249959 0,03150928 ! cell junction assembly GO:0034329 85 31 0,000 0,0249959 0,03149303 ! regulation of innate immune response GO:0045088 57 31 0,000 0,0249959 0,0314768 ! ovulation cycle process GO:0022602 55 31 0,000 0,0249959 0,03146058 ! peptide transport GO:0015833 60 31 0,000 0,0249959 0,03144438 ! male gonad development GO:0008584 56 31 0,000 0,0249959 0,0314282 ! iron ion homeostasis GO:0055072 60 31 0,000 0,0249959 0,03141203 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,0249959 0,03139588 ! detection of light stimulus GO:0009583 44 31 0,000 0,0249959 0,03137975 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,0249959 0,03136363 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,0249959 0,03134753 ! natural killer cell activation GO:0030101 50 31 0,000 0,0249959 0,03133145 ! ensheathment of neurons GO:0007272 64 31 0,000 0,0249959 0,03131538 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,0249959 0,03129933 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,0249959 0,0312833 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,0249959 0,03126728 ! eye morphogenesis GO:0048592 65 31 0,000 0,0249959 0,03125128 ! response to heat GO:0009408 54 31 0,000 0,0249959 0,03123529 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,0249959 0,03121932 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,02579209 0,03219729 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,02579209 0,03218084 ! collagen metabolic process GO:0032963 49 32 0,000 0,02579209 0,03216441 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,02579209 0,032148 ! spindle organization GO:0007051 50 32 0,000 0,02579209 0,03213161 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,02579209 0,03211523 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,02579209 0,03209887 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,02579209 0,03208253 ! muscle cell development GO:0055001 52 32 0,000 0,02579209 0,0320662 ! mesoderm formation GO:0001707 73 32 0,000 0,02579209 0,03204989 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,02579209 0,0320336 ! ovulation cycle GO:0042698 57 32 0,000 0,02579209 0,03201732 ! peripheral nervous system development GO:0007422 68 32 0,000 0,02579209 0,03200106 ! BMP signaling pathway GO:0030509 71 32 0,000 0,02579209 0,03198482 ! hindbrain development GO:0030902 65 32 0,000 0,02579209 0,03196859 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,02579209 0,03195238 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,02579209 0,03193618 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,02579209 0,03192 ! gene silencing GO:0016458 71 32 0,000 0,02579209 0,03190384 ! regulation of pH GO:0006885 56 33 0,000 0,02658766 0,03287128 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,02658766 0,03285465 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,02658766 0,03283804 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,02658766 0,03282145 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,02658766 0,03280487 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,02658766 0,03278831 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,02658766 0,03277177 ! response to ionizing radiation GO:0010212 74 33 0,000 0,02658766 0,03275524 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,02658766 0,03273873 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,02658766 0,03272224 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,02658766 0,03270576 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,02658766 0,0326893 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,02658766 0,03267286 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,02658766 0,03265643 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,02738259 0,03361592 ! glial cell differentiation GO:0010001 67 34 0,000 0,02738259 0,03359903 ! post-embryonic development GO:0009791 76 34 0,000 0,02738259 0,03358217 ! cholesterol transport GO:0030301 62 34 0,000 0,02738259 0,03356532 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,02738259 0,03354848 ! spliceosome assembly GO:0000245 75 34 0,000 0,02738259 0,03353167 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,02738259 0,03351487 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,02738259 0,03349809 ! formation of primary germ layer GO:0001704 76 34 0,000 0,02738259 0,03348132 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,02738259 0,03346457 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,02738259 0,03344784 ! adult locomotory behavior GO:0008344 62 34 0,000 0,02738259 0,03343112 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,02738259 0,03341442 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,0281769 0,03436654 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,0281769 0,03434939 ! negative regulation of secretion GO:0051048 68 35 0,000 0,0281769 0,03433226 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,0281769 0,03431514 ! membrane docking GO:0022406 69 35 0,000 0,0281769 0,03429804 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,0281769 0,03428096 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,0281769 0,0342639 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,0281769 0,03424685 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,0281769 0,03422982 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,0281769 0,03421281 ! ceramide metabolic process GO:0006672 72 35 0,000 0,0281769 0,03419581 ! telencephalon development GO:0021537 81 35 0,000 0,0281769 0,03417883 ! sterol transport GO:0015918 63 35 0,000 0,0281769 0,03416187 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,0281769 0,03414493 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,0281769 0,034128 ! placenta development GO:0001890 53 35 0,000 0,0281769 0,03411109 ! vesicle localization GO:0051648 70 35 0,000 0,0281769 0,03409419 ! regulation of muscle development GO:0048634 82 36 0,000 0,02897058 0,0350372 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,02897058 0,03501986 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,02897058 0,03500254 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,02897058 0,03498524 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,02897058 0,03496795 ! positive regulation of cell development GO:0010720 85 36 0,000 0,02897058 0,03495069 ! protein targeting to membrane GO:0006612 75 36 0,000 0,02897058 0,03493343 ! regulation of proteolysis GO:0030162 77 36 0,000 0,02897058 0,0349162 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,02897058 0,03489898 ! aerobic respiration GO:0009060 56 36 0,000 0,02897058 0,03488178 ! cytokine production GO:0001816 68 36 0,000 0,02897058 0,0348646 ! embryonic organ development GO:0048568 67 36 0,000 0,02897058 0,03484743 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,02897058 0,03483028 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,02897058 0,03481315 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,02976364 0,03574856 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,02976364 0,035731 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,02976364 0,03571345 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,02976364 0,03569591 ! sister chromatid segregation GO:0000819 65 37 0,000 0,02976364 0,0356784 ! odontogenesis GO:0042476 74 37 0,000 0,02976364 0,0356609 ! actomyosin structure organization GO:0031032 68 37 0,000 0,02976364 0,03564342 ! cell junction organization GO:0034330 96 37 0,000 0,02976364 0,03562596 ! tissue remodeling GO:0048771 78 37 0,000 0,02976364 0,03560851 ! female gonad development GO:0008585 71 37 0,000 0,02976364 0,03559108 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,02976364 0,03557367 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,02976364 0,03555627 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,02976364 0,03553889 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,02976364 0,03552153 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,03055607 0,03644946 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,03055607 0,03643167 ! meiosis I GO:0007127 74 38 0,000 0,03055607 0,0364139 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,03055607 0,03639614 ! organic anion transport GO:0015711 82 38 0,000 0,03055607 0,0363784 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,03055607 0,03636068 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,03055607 0,03634298 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,03055607 0,0363253 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,03055607 0,03630763 ! regulation of protein stability GO:0031647 77 38 0,000 0,03055607 0,03628998 ! spermatid development GO:0007286 69 38 0,000 0,03055607 0,03627234 ! glycogen metabolic process GO:0005977 63 38 0,000 0,03055607 0,03625473 ! pigment metabolic process GO:0042440 87 38 0,000 0,03055607 0,03623713 ! neural tube formation GO:0001841 79 38 0,000 0,03055607 0,03621955 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,03134788 0,03714009 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,03134788 0,03712209 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,03134788 0,0371041 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,03134788 0,03708613 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,03134788 0,03706818 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,03134788 0,03705025 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,03134788 0,03703233 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,03134788 0,03701444 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,03134788 0,03699655 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,03134788 0,03697869 ! glucan metabolic process GO:0044042 64 39 0,000 0,03134788 0,03696084 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,03213906 0,03787541 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,03213906 0,03785715 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,03213906 0,0378389 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,03213906 0,03782068 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,03213906 0,03780247 ! lipid homeostasis GO:0055088 75 40 0,000 0,03213906 0,03778428 ! mismatch repair GO:0006298 58 40 0,000 0,03213906 0,0377661 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,03213906 0,03774794 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,03213906 0,03772981 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,03213906 0,03771168 ! RNA export from nucleus GO:0006405 61 41 0,000 0,03292962 0,03862077 ! mRNA catabolic process GO:0006402 79 41 0,000 0,03292962 0,03860224 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,03292962 0,03858372 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,03292962 0,03856522 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,03292962 0,03854675 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,03292962 0,03852828 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,03292962 0,03850984 ! gliogenesis GO:0042063 91 41 0,000 0,03292962 0,03849142 ! feeding behavior GO:0007631 69 41 0,000 0,03292962 0,03847301 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,03292962 0,03845462 ! mesenchymal cell development GO:0014031 94 41 0,000 0,03292962 0,03843624 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,03292962 0,03841789 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,03292962 0,03839955 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,03292962 0,03838123 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,03292962 0,03836293 ! RNA modification GO:0009451 64 41 0,000 0,03292962 0,03834464 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,03371955 0,03924577 ! organic ether metabolic process GO:0018904 59 42 0,000 0,03371955 0,03922708 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,03371955 0,03920841 ! T cell differentiation GO:0030217 93 42 0,000 0,03371955 0,03918976 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,03371955 0,03917112 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,03371955 0,0391525 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,03371955 0,0391339 ! regulation of protein secretion GO:0050708 77 42 0,000 0,03371955 0,03911532 ! cytokinesis GO:0000910 84 42 0,000 0,03371955 0,03909676 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,03371955 0,03907821 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,03450886 0,03997399 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,03450886 0,03995505 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,03450886 0,03993612 ! regulation of tube size GO:0035150 76 43 0,000 0,03450886 0,03991721 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,03450886 0,03989832 ! glucose transport GO:0015758 66 43 0,000 0,03450886 0,03987945 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,03450886 0,03986059 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,03450886 0,03984176 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,03450886 0,03982294 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,03450886 0,03980413 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,03450886 0,03978535 ! segmentation GO:0035282 78 43 0,000 0,03450886 0,03976658 ! ion transmembrane transport GO:0034220 79 43 0,000 0,03450886 0,03974783 ! neuron migration GO:0001764 85 43 0,000 0,03450886 0,0397291 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,03450886 0,03971039 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,03529755 0,04059883 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,03529755 0,04057973 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,03529755 0,04056064 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,03529755 0,04054157 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,03529755 0,04052252 ! hexose transport GO:0008645 68 44 0,000 0,03529755 0,04050349 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,03529755 0,04048447 ! striated muscle contraction GO:0006941 85 44 0,000 0,03529755 0,04046547 ! phagocytosis GO:0006909 105 44 0,000 0,03529755 0,04044649 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,03529755 0,04042753 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,03608562 0,04131076 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,03608562 0,04129141 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,03608562 0,04127208 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,03608562 0,04125277 ! B cell differentiation GO:0030183 124 45 0,000 0,03608562 0,04123347 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,03608562 0,0412142 ! female gamete generation GO:0007292 71 45 0,000 0,03608562 0,04119494 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,03608562 0,0411757 ! polyol metabolic process GO:0019751 77 45 0,000 0,03608562 0,04115648 ! developmental growth GO:0048589 88 45 0,000 0,03608562 0,04113727 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,03687307 0,04201534 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,03687307 0,04199576 ! glycolysis GO:0006096 71 46 0,000 0,03687307 0,04197619 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,03687307 0,04195664 ! leukocyte migration GO:0050900 75 46 0,000 0,03687307 0,0419371 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,03687307 0,04191759 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,03687307 0,04189809 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,03687307 0,04187861 ! pigmentation GO:0043473 103 46 0,000 0,03687307 0,04185915 ! cell growth GO:0016049 90 46 0,000 0,03687307 0,04183971 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,03687307 0,04182029 ! neural tube development GO:0021915 91 47 0,000 0,03765989 0,04269286 ! positive regulation of defense response GO:0031349 88 48 0,000 0,03844609 0,04356392 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,03844609 0,04354372 ! mitochondrial transport GO:0006839 94 48 0,000 0,03844609 0,04352354 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,03844609 0,04350338 ! cellular component disassembly GO:0022411 89 48 0,000 0,03844609 0,04348324 ! endosome transport GO:0016197 127 48 0,000 0,03844609 0,04346312 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,03844609 0,04344302 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,03844609 0,04342293 ! male sex differentiation GO:0046661 93 48 0,000 0,03844609 0,04340287 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,03844609 0,04338282 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,03844609 0,04336279 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,03844609 0,04334278 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,03844609 0,04332279 ! methylation GO:0032259 97 48 0,000 0,03844609 0,04330281 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,03923168 0,04416727 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,03923168 0,04414693 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,03923168 0,0441266 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,03923168 0,0441063 ! protein homooligomerization GO:0051260 84 49 0,000 0,03923168 0,04408601 ! regulation of action potential GO:0001508 102 50 0,000 0,04001664 0,04494743 ! regulation of ion transport GO:0043269 86 50 0,000 0,04001664 0,04492677 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,04001664 0,04490613 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,04001664 0,04488551 ! activation of caspase activity GO:0006919 95 50 0,000 0,04001664 0,04486492 ! regulation of ossification GO:0030278 123 50 0,000 0,04001664 0,04484433 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,04001664 0,04482377 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,04001664 0,04480323 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,04001664 0,04478271 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,04001664 0,0447622 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,04080098 0,04561867 ! viral infectious cycle GO:0019058 104 51 0,000 0,04080098 0,04559781 ! peptide metabolic process GO:0006518 80 51 0,000 0,04080098 0,04557696 ! response to temperature stimulus GO:0009266 84 51 0,000 0,04080098 0,04555613 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,04080098 0,04553531 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,04080098 0,04551452 ! positive regulation of binding GO:0051099 88 52 0,000 0,04158471 0,04636762 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,04158471 0,04634646 ! Notch signaling pathway GO:0007219 111 52 0,000 0,04158471 0,04632533 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,04158471 0,04630421 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,04158471 0,04628312 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,04158471 0,04626204 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,04158471 0,04624099 ! excretion GO:0007588 87 52 0,000 0,04158471 0,04621995 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,04158471 0,04619893 ! histone modification GO:0016570 104 52 0,000 0,04158471 0,04617793 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,04158471 0,04615695 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,04158471 0,04613599 ! amino acid activation GO:0043038 98 52 0,000 0,04158471 0,04611505 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,04236782 0,04696215 ! positive regulation of growth GO:0045927 96 53 0,000 0,04236782 0,04694085 ! chromatin remodeling GO:0006338 122 53 0,000 0,04236782 0,04691957 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,04236782 0,04689831 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,04236782 0,04687707 ! vesicle organization GO:0016050 127 53 0,000 0,04236782 0,04685585 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,04236782 0,04683465 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 0,000 0,04236782 0,04681347 ! synapse organization GO:0050808 102 53 0,000 0,04236782 0,0467923 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,04315031 0,04763497 ! regulation of translational initiation GO:0006446 87 54 0,000 0,04315031 0,04761346 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,04315031 0,04759196 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,04315031 0,04757049 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,04315031 0,04754903 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,04315031 0,04752759 ! membrane fusion GO:0006944 122 54 0,000 0,04315031 0,04750617 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,04315031 0,04748477 ! covalent chromatin modification GO:0016569 115 54 0,000 0,04315031 0,04746339 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,04315031 0,04744203 ! regulation of cell shape GO:0008360 142 54 0,000 0,04315031 0,04742069 ! RNA catabolic process GO:0006401 103 55 0,000 0,04393218 0,04825823 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,04393218 0,04823654 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,04393218 0,04821487 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,04393218 0,04819322 ! cell recognition GO:0008037 98 55 0,000 0,04393218 0,04817159 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,04393218 0,04814998 ! cell maturation GO:0048469 107 55 0,000 0,04393218 0,04812839 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,04393218 0,04810682 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,04393218 0,04808526 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,04471343 0,04891846 ! glucose catabolic process GO:0006007 88 56 0,000 0,04471343 0,04889656 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,04471343 0,04887468 ! RNA elongation GO:0006354 90 56 0,000 0,04471343 0,04885283 ! chloride transport GO:0006821 102 57 0,000 0,04549407 0,04968351 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,04549407 0,04966131 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,04549407 0,04963913 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,04549407 0,04961697 ! heart morphogenesis GO:0003007 105 57 0,000 0,04549407 0,04959483 ! regulation of actin filament length GO:0030832 118 58 0,000 0,0462741 0,05042266 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,0462741 0,05040018 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,0462741 0,05037772 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,0462741 0,05035528 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,0462741 0,05033286 ! gastrulation GO:0007369 122 58 0,000 0,0462741 0,05031046 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,0462741 0,05028808 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,0462741 0,05026572 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,0462741 0,05024338 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,0462741 0,05022106 ! nuclear export GO:0051168 110 59 0,000 0,0470535 0,05104427 ! establishment of organelle localization GO:0051656 122 59 0,000 0,0470535 0,05102162 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,04783229 0,05184308 ! lipid modification GO:0030258 112 60 0,000 0,04783229 0,05182009 ! DNA catabolic process GO:0006308 94 60 0,000 0,04783229 0,05179712 ! regulation of endocytosis GO:0030100 104 60 0,000 0,04783229 0,05177417 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,04783229 0,05175124 ! adult behavior GO:0030534 104 60 0,000 0,04783229 0,05172833 ! positive regulation of secretion GO:0051047 110 61 0,000 0,04861047 0,05254663 ! regulation of cellular component size GO:0032535 125 61 0,000 0,04861047 0,05252339 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,04861047 0,05250017 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,04861047 0,05247697 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,04861047 0,05245379 ! regulation of heart contraction GO:0008016 123 61 0,000 0,04861047 0,05243063 ! camera-type eye development GO:0043010 126 61 0,000 0,04861047 0,0524075 ! proton transport GO:0015992 117 61 0,000 0,04861047 0,05238438 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,04861047 0,05236128 ! viral reproductive process GO:0022415 132 62 0,000 0,04938804 0,0531754 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,04938804 0,05315197 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,04938804 0,05312857 ! tRNA processing GO:0008033 102 62 0,000 0,04938804 0,05310518 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,05016499 0,05391688 ! regulation of mitosis GO:0007088 112 63 0,000 0,05016499 0,05389317 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,05016499 0,05386948 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,05016499 0,05384581 ! hydrogen transport GO:0006818 121 64 0,000 0,05094132 0,0546551 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,05094132 0,0546311 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,05094132 0,05460713 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,05094132 0,05458318 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,05171705 0,05539007 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,05171705 0,0553658 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,05171705 0,05534155 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,05171705 0,05531732 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,05171705 0,05529311 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,05171705 0,05526892 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,05249216 0,05607274 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,05249216 0,05604823 ! gonad development GO:0008406 115 66 0,000 0,05249216 0,05602374 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,05249216 0,05599928 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,05326666 0,05680072 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,05326666 0,05677594 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,05326666 0,05675118 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,05326666 0,05672644 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,05326666 0,05670172 ! secondary metabolic process GO:0019748 125 67 0,000 0,05326666 0,05667703 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,05326666 0,05665235 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,05404055 0,05745042 ! hexose catabolic process GO:0019320 113 68 0,000 0,05404055 0,05742543 ! extracellular matrix organization GO:0030198 146 68 0,000 0,05404055 0,05740046 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,05404055 0,05737552 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,05404055 0,05735059 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,05404055 0,05732569 ! viral reproduction GO:0016032 142 68 0,000 0,05404055 0,05730081 ! regulation of lipase activity GO:0060191 137 68 0,000 0,05404055 0,05727595 ! adaptive immune response GO:0002250 126 68 0,000 0,05404055 0,05725111 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,05404055 0,0572263 ! negative regulation of cell size GO:0045792 144 69 0,000 0,05481383 0,05802001 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,05481383 0,05799488 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,05481383 0,05796978 ! lung development GO:0030324 165 69 0,000 0,05481383 0,05794469 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,05481383 0,05791963 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,05481383 0,05789459 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,05481383 0,05786957 ! developmental maturation GO:0021700 128 69 0,000 0,05481383 0,05784457 ! single fertilization GO:0007338 83 69 0,000 0,05481383 0,0578196 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,0555865 0,05860933 ! cell redox homeostasis GO:0045454 114 70 0,000 0,0555865 0,05858404 ! germ cell development GO:0007281 133 70 0,000 0,0555865 0,05855878 ! activation of immune response GO:0002253 120 70 0,000 0,0555865 0,05853354 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,0555865 0,05850832 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,05635855 0,05929541 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,05635855 0,05926989 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,05635855 0,05924438 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,05635855 0,0592189 ! appendage morphogenesis GO:0035107 150 72 0,000 0,05713 0,0600037 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,05713 0,05997791 ! respiratory tube development GO:0030323 171 72 0,000 0,05713 0,05995215 ! actin filament organization GO:0007015 167 72 0,000 0,05713 0,05992641 ! B cell activation GO:0042113 179 72 0,000 0,05713 0,05990069 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,05713 0,05987499 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,05713 0,05984931 ! appendage development GO:0048736 151 73 0,000 0,05790084 0,06063084 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,05790084 0,06060487 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,05790084 0,06057891 ! regulation of immune effector process GO:0002697 156 73 0,000 0,05790084 0,06055298 ! acute inflammatory response GO:0002526 118 74 0,000 0,05867107 0,06133224 ! amino acid transport GO:0006865 148 74 0,000 0,05867107 0,061306 ! regulation of caspase activity GO:0043281 136 74 0,000 0,05867107 0,06127979 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,05867107 0,0612536 ! respiratory system development GO:0060541 175 74 0,000 0,05867107 0,06122744 ! organelle localization GO:0051640 155 74 0,000 0,05867107 0,0612013 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,0594407 0,06197765 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,0594407 0,06195121 ! reproductive structure development GO:0048608 131 75 0,000 0,0594407 0,06192479 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,0594407 0,06189839 ! eye development GO:0001654 155 75 0,000 0,0594407 0,06187202 ! axon guidance GO:0007411 162 75 0,000 0,0594407 0,06184567 ! rhythmic process GO:0048511 142 75 0,000 0,0594407 0,06181934 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,06020971 0,06259248 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,06020971 0,06256586 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,06020971 0,06253926 ! regulation of blood pressure GO:0008217 134 76 0,000 0,06020971 0,06251268 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,06020971 0,06248612 ! amine catabolic process GO:0009310 136 77 0,000 0,06097812 0,06325671 ! neurotransmitter transport GO:0006836 142 77 0,000 0,06097812 0,06322986 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,06097812 0,06320303 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,06097812 0,06317623 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,06097812 0,06314945 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,06097812 0,06312269 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,06097812 0,06309596 ! regulation of catabolic process GO:0009894 173 77 0,000 0,06097812 0,06306924 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,06174592 0,06383635 ! antigen processing and presentation GO:0019882 117 78 0,000 0,06174592 0,06380935 ! fertilization GO:0009566 99 78 0,000 0,06174592 0,06378236 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,06174592 0,06375541 ! blood coagulation GO:0007596 151 79 0,000 0,06251312 0,0645203 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,06251312 0,06449305 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,06251312 0,06446583 ! protein oligomerization GO:0051259 149 79 0,000 0,06251312 0,06443863 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,06327971 0,06520132 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,06327971 0,06517383 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,06327971 0,06514637 ! meiosis GO:0007126 143 81 0,000 0,0640457 0,06590718 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 0,000 0,0640457 0,06587942 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,0640457 0,0658517 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,06481108 0,06661063 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,06481108 0,06658261 ! protein import into nucleus GO:0006606 174 82 0,000 0,06481108 0,06655463 ! meiotic cell cycle GO:0051321 144 82 0,000 0,06481108 0,06652666 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,06557585 0,06728341 ! exocytosis GO:0006887 153 83 0,000 0,06557585 0,06725517 ! response to drug GO:0042493 149 83 0,000 0,06557585 0,06722694 ! response to oxygen levels GO:0070482 183 83 0,000 0,06557585 0,06719874 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,06557585 0,06717057 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,06557585 0,06714242 ! nuclear import GO:0051170 177 83 0,000 0,06557585 0,06711429 ! inorganic anion transport GO:0015698 156 83 0,000 0,06557585 0,06708618 ! T cell activation GO:0042110 189 84 0,000 0,06634002 0,06783955 ! response to nutrient GO:0007584 135 84 0,000 0,06634002 0,06781116 ! digestion GO:0007586 130 84 0,000 0,06634002 0,0677828 ! hemostasis GO:0007599 165 85 0,000 0,06710359 0,06853431 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,06710359 0,06850567 ! negative regulation of growth GO:0045926 168 85 0,000 0,06710359 0,06847706 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,06710359 0,06844847 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,06786656 0,06919783 ! regulation of lyase activity GO:0051339 169 86 0,000 0,06786656 0,06916896 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,06786656 0,06914012 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,06862892 0,06988764 ! mitochondrion organization GO:0007005 159 87 0,000 0,06862892 0,06985852 ! alcohol catabolic process GO:0046164 142 87 0,000 0,06862892 0,06982943 ! nucleosome assembly GO:0006334 126 87 0,000 0,06862892 0,06980035 ! cellular respiration GO:0045333 143 88 0,000 0,06939068 0,07054575 ! amine biosynthetic process GO:0009309 146 88 0,000 0,06939068 0,0705164 ! sensory perception of smell GO:0007608 117 88 0,000 0,06939068 0,07048708 ! chromatin assembly GO:0031497 128 88 0,000 0,06939068 0,07045779 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,06939068 0,07042851 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,07015184 0,07117149 ! cellular defense response GO:0006968 123 89 0,000 0,07015184 0,07114195 ! protein localization in nucleus GO:0034504 192 89 0,000 0,07015184 0,07111243 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,0709124 0,07185358 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,0709124 0,07182379 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,07167236 0,07256343 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,07167236 0,07253338 ! defense response to bacterium GO:0042742 112 91 0,000 0,07167236 0,07250334 ! bone development GO:0060348 206 92 0,000 0,07243171 0,07324117 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,07243171 0,07321087 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,07243171 0,07318059 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,07319047 0,07391663 ! amine transport GO:0015837 181 93 0,000 0,07319047 0,07388608 ! vitamin metabolic process GO:0006766 153 93 0,000 0,07319047 0,07385557 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,07394863 0,0745898 ! female pregnancy GO:0007565 166 94 0,000 0,07394863 0,07455902 ! sterol metabolic process GO:0016125 166 94 0,000 0,07394863 0,07452826 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,07394863 0,07449753 ! regulation of membrane potential GO:0042391 179 94 0,000 0,07394863 0,07446682 ! regulation of defense response GO:0031347 171 95 0,000 0,07470619 0,07519869 ! nucleosome organization GO:0034728 143 95 0,000 0,07470619 0,07516772 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,07470619 0,07513677 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,07470619 0,07510585 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,07470619 0,07507496 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,07470619 0,07504409 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,07470619 0,07501324 ! sex differentiation GO:0007548 171 96 0,000 0,07546315 0,07574219 ! regulation of T cell activation GO:0050863 175 96 0,000 0,07546315 0,07571108 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,07621951 0,07643854 ! transcription initiation GO:0006352 171 97 0,000 0,07621951 0,07640717 ! leukocyte differentiation GO:0002521 232 98 0,000 0,07697528 0,07713315 ! forebrain development GO:0030900 210 98 0,000 0,07697528 0,07710152 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,07697528 0,07706992 ! mRNA transport GO:0051028 185 100 0,000 0,07848502 0,07854933 ! positive regulation of immune response GO:0050778 175 100 0,000 0,07848502 0,07851716 ! hormone metabolic process GO:0042445 171 100 0,000 0,07848502 0,07848502