pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/51022-5-real-Loi_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cell redox homeostasis GO:0045454 102 64 4,000 1,207E-09 2,904E-06 ! response to hydrogen peroxide GO:0042542 50 32 3,000 9,16E-09 1,102E-05 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 2,000 1,359E-08 1,09E-05 ! response to reactive oxygen species GO:0000302 67 42 3,000 2,837E-08 1,706E-05 ! nucleoside diphosphate metabolic process GO:0009132 13 9 2,000 3,258E-08 1,568E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 9,936E-08 3,984E-05 ! cellular response to hydrogen peroxide GO:0070301 23 18 2,000 3,151E-07 1,083E-04 GO:0042744|hydrogen peroxide catabolic process, ! protein oligomerization GO:0051259 139 78 3,000 3,55E-07 1,068E-04 ! deoxyribonucleotide metabolic process GO:0009262 32 22 2,000 5,935E-07 1,587E-04 ! cellular response to reactive oxygen species GO:0034614 31 22 2,000 5,935E-07 1,428E-04 ! hydrogen peroxide metabolic process GO:0042743 33 25 2,000 8,85E-07 1,936E-04 ! cellular response to oxidative stress GO:0034599 39 26 2,000 9,999E-07 2,005E-04 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,403E-06 2,597E-04 ! mesoderm formation GO:0001707 69 31 2,000 1,724E-06 2,964E-04 ! formation of primary germ layer GO:0001704 72 33 2,000 2,091E-06 3,354E-04 ! mesoderm morphogenesis GO:0048332 76 34 2,000 2,292E-06 3,447E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 5,406E-06 7,651E-04 ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 5,571E-06 7,447E-04 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 5,571E-06 7,055E-04 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 5,571E-06 6,702E-04 ! response to redox state GO:0051775 5 5 1,000 5,571E-06 6,383E-04 GO:0006980|redox signal response, ! activation of Ras GTPase activity GO:0032856 10 5 1,000 5,571E-06 6,093E-04 GO:0032862|activation of Rho GTPase activity, ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 5,78E-06 6,047E-04 ! response to UV GO:0009411 104 53 2,000 8,889E-06 8,911E-04 ! gastrulation GO:0007369 112 55 2,000 9,945E-06 9,571E-04 ! protein thiol-disulfide exchange GO:0006467 9 7 1,000 1,169E-05 1,082E-03 ! mesoderm development GO:0007498 119 61 2,000 1,36E-05 1,212E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,558E-05 1,339E-03 ! DNA topological change GO:0006265 12 8 1,000 1,558E-05 1,292E-03 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 1,558E-05 1,249E-03 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 2,000 1,572E-05 1,22E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 1,805E-05 1,357E-03 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,888E-05 1,376E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 2,002E-05 1,417E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 2,002E-05 1,376E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 2,002E-05 1,338E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 2,242E-05 1,458E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,501E-05 1,584E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,501E-05 1,543E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 2,501E-05 1,504E-03 ! regulation of stress fiber formation GO:0051492 30 10 1,000 2,501E-05 1,468E-03 ! DNA ligation GO:0006266 19 10 1,000 2,501E-05 1,433E-03 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 2,501E-05 1,399E-03 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 2,501E-05 1,368E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 3,056E-05 1,634E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 3,665E-05 1,917E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 3,665E-05 1,876E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 4,329E-05 2,17E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 5,048E-05 2,479E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 5,048E-05 2,429E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 5,048E-05 2,382E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 5,144E-05 2,38E-03 ! interphase GO:0051325 213 98 2,000 5,643E-05 2,562E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 5,822E-05 2,594E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 6,651E-05 2,91E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 6,651E-05 2,858E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 7,534E-05 3,18E-03 ! regulation of viral genome replication GO:0045069 28 17 1,000 7,534E-05 3,126E-03 ! skin development GO:0043588 36 19 1,000 9,465E-05 3,86E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 9,465E-05 3,795E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,051E-04 4,146E-03 ! negative regulation of translation GO:0017148 29 20 1,000 1,051E-04 4,079E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 1,161E-04 4,435E-03 ! apoptotic nuclear changes GO:0030262 32 22 1,000 1,277E-04 4,8E-03 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,277E-04 4,726E-03 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,398E-04 5,095E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 1,398E-04 5,019E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of viral reproduction GO:0050792 38 23 1,000 1,398E-04 4,945E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,524E-04 5,314E-03 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,524E-04 5,239E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,656E-04 5,611E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 1,656E-04 5,533E-03 ! chromosome condensation GO:0030261 45 25 1,000 1,656E-04 5,457E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,656E-04 5,384E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 1,793E-04 5,752E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 1,936E-04 6,128E-03 ! fat cell differentiation GO:0045444 50 27 1,000 1,936E-04 6,048E-03 ! glutathione metabolic process GO:0006749 39 27 1,000 1,936E-04 5,97E-03 ! negative regulation of protein modification process GO:0031400 60 28 1,000 2,083E-04 6,345E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,083E-04 6,266E-03 ! regulation of B cell activation GO:0050864 50 30 1,000 2,395E-04 7,115E-03 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 3,269E-04 9,591E-03 ! RNA export from nucleus GO:0006405 56 37 1,000 3,656E-04 0,01059667 ! nucleus organization GO:0006997 67 38 1,000 3,857E-04 0,01104708 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 3,857E-04 0,01091711 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! keratinocyte differentiation GO:0030216 62 41 1,000 4,492E-04 0,01256845 ! epidermal cell differentiation GO:0009913 68 46 1,000 5,657E-04 0,01564513 ! response to insulin stimulus GO:0032868 95 46 1,000 5,657E-04 0,01546734 ! response to calcium ion GO:0051592 81 47 1,000 5,906E-04 0,01596585 ! positive regulation of cell cycle GO:0045787 89 48 1,000 6,16E-04 0,01646726 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 6,16E-04 0,0162863 ! peptide metabolic process GO:0006518 76 49 1,000 6,419E-04 0,01678698 ! response to temperature stimulus GO:0009266 76 49 1,000 6,419E-04 0,01660647 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 6,953E-04 0,0177964 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 1,000 7,228E-04 0,01830493 ! nuclear export GO:0051168 97 55 1,000 8,083E-04 0,0202581 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 9,612E-04 0,02384169 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 9,933E-04 0,02438704 ! negative regulation of cell growth GO:0030308 132 67 1,000 1,197E-03 0,02908563 ! chromosome segregation GO:0007059 113 67 1,000 1,197E-03 0,02879477 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 1,232E-03 0,02935998 ! negative regulation of cell size GO:0045792 134 69 1,000 1,269E-03 0,02992607 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 1,269E-03 0,02963553 ! regulation of caspase activity GO:0043281 122 72 1,000 1,38E-03 0,03193338 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,38E-03 0,03162926 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 1,38E-03 0,03133087 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 1,38E-03 0,03103805 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 1,457E-03 0,03246499 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 1,457E-03 0,03216715 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 1,497E-03 0,03273281 ! regulation of actin filament-based process GO:0032970 152 77 1,000 1,576E-03 0,0341713 ! positive regulation of ligase activity GO:0051351 124 77 1,000 1,576E-03 0,0338662 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 1,576E-03 0,0335665 ! regulation of peptidase activity GO:0052547 134 79 1,000 1,658E-03 0,0350021 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 1,658E-03 0,03469774 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 1,658E-03 0,03439862 ! response to metal ion GO:0010038 140 80 1,000 1,7E-03 0,03496287 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 1,742E-03 0,03552773 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of growth GO:0045926 155 84 1,000 1,872E-03 0,03785129 ! regulation of ligase activity GO:0051340 142 84 1,000 1,872E-03 0,03753586 ! response to unfolded protein GO:0006986 131 85 1,000 1,916E-03 0,03810498 ! positive regulation of cell activation GO:0050867 145 85 1,000 1,916E-03 0,03779264 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 1,961E-03 0,0383601 ! mitochondrion organization GO:0007005 148 86 1,000 1,961E-03 0,03805075 ! positive regulation of protein modification process GO:0031401 136 88 1,000 2,052E-03 0,03949632 ! regulation of cell adhesion GO:0030155 212 89 1,000 2,098E-03 0,04006503 ! response to protein stimulus GO:0051789 149 91 1,000 2,192E-03 0,04152799 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 2,288E-03 0,04300499 GO:0010498|proteasomal protein catabolic process, ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 2,386E-03 0,04449561 ! cell cycle arrest GO:0007050 213 100 1,000 2,639E-03 0,04883607 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 3,813E-03 0,07002868 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 3,813E-03 0,06949816 ! positive regulation of helicase activity GO:0051096 11 5 0,000 3,813E-03 0,06897561 ! neuron fate determination GO:0048664 7 5 0,000 3,813E-03 0,06846087 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,813E-03 0,06795375 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 3,813E-03 0,06745409 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 3,813E-03 0,06696173 ! polyol transport GO:0015791 12 5 0,000 3,813E-03 0,0664765 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 3,813E-03 0,06599825 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 3,813E-03 0,06552683 ! response to superoxide GO:0000303 10 5 0,000 3,813E-03 0,0650621 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,813E-03 0,06460392 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 3,813E-03 0,06415215 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 3,813E-03 0,06370664 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 3,813E-03 0,06326729 ! female meiosis GO:0007143 7 5 0,000 3,813E-03 0,06283395 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,813E-03 0,06240651 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 3,813E-03 0,06198484 ! cobalt ion transport GO:0006824 11 5 0,000 3,813E-03 0,06156884 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 3,813E-03 0,06115838 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 3,813E-03 0,06075336 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 3,813E-03 0,06035366 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 3,813E-03 0,05995919 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 3,813E-03 0,05956985 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 3,813E-03 0,05918553 ! embryonic camera-type eye development GO:0031076 10 5 0,000 3,813E-03 0,05880613 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 3,813E-03 0,05843157 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 3,813E-03 0,05806175 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 3,813E-03 0,05769658 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,813E-03 0,05733598 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,813E-03 0,05697986 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,813E-03 0,05662813 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 3,813E-03 0,05628072 ! negative chemotaxis GO:0050919 14 5 0,000 3,813E-03 0,05593754 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,813E-03 0,05559853 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 3,813E-03 0,0552636 ! sensory perception of bitter taste GO:0050913 7 5 0,000 3,813E-03 0,05493268 ! behavioral response to pain GO:0048266 9 5 0,000 3,813E-03 0,0546057 ! clathrin coat assembly GO:0048268 14 5 0,000 3,813E-03 0,05428258 ! Notch receptor processing GO:0007220 8 5 0,000 3,813E-03 0,05396328 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,813E-03 0,0536477 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,813E-03 0,0533358 ! micturition GO:0060073 9 5 0,000 3,813E-03 0,0530275 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 3,813E-03 0,05272274 ! copulation GO:0007620 9 5 0,000 3,813E-03 0,05242147 ! glial cell fate commitment GO:0021781 13 5 0,000 3,813E-03 0,05212362 ! protein maturation by protein folding GO:0022417 13 5 0,000 3,813E-03 0,05182913 ! spermidine metabolic process GO:0008216 7 5 0,000 3,813E-03 0,05153796 ! regulation of potassium ion transport GO:0043266 10 5 0,000 3,813E-03 0,05125004 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 3,813E-03 0,05096532 ! apoptotic cell clearance GO:0043277 20 5 0,000 3,813E-03 0,05068374 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 3,813E-03 0,05040526 ! lipoprotein particle clearance GO:0034381 10 5 0,000 3,813E-03 0,05012982 ! grooming behavior GO:0007625 6 5 0,000 3,813E-03 0,04985737 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 3,813E-03 0,04958787 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 3,813E-03 0,04932127 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,813E-03 0,04905752 ! response to protozoan GO:0001562 10 5 0,000 3,813E-03 0,04879658 ! positive regulation of glycolysis GO:0045821 14 5 0,000 3,813E-03 0,0485384 ! lymph vessel development GO:0001945 10 5 0,000 3,813E-03 0,04828293 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 3,813E-03 0,04803014 ! endochondral ossification GO:0001958 16 5 0,000 3,813E-03 0,04777998 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 3,813E-03 0,04753242 ! parathyroid gland development GO:0060017 13 5 0,000 3,813E-03 0,04728741 ! anagen GO:0042640 6 5 0,000 3,813E-03 0,04704491 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 3,813E-03 0,04680488 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 3,813E-03 0,04656729 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 3,813E-03 0,0463321 ! dorsal spinal cord development GO:0021516 7 5 0,000 3,813E-03 0,04609928 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 3,813E-03 0,04586878 ! sphingoid catabolic process GO:0046521 6 5 0,000 3,813E-03 0,04564058 ! skeletal myofibril assembly GO:0014866 10 5 0,000 3,813E-03 0,04541464 ! smooth muscle tissue development GO:0048745 28 5 0,000 3,813E-03 0,04519092 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 3,813E-03 0,0449694 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 3,813E-03 0,04475003 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 3,813E-03 0,0445328 ! cardiac muscle fiber development GO:0048739 10 5 0,000 3,813E-03 0,04431767 ! transepithelial chloride transport GO:0030321 9 5 0,000 3,813E-03 0,0441046 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 3,813E-03 0,04389357 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 3,813E-03 0,04368456 ! neutrophil mediated immunity GO:0002446 7 5 0,000 3,813E-03 0,04347752 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 3,813E-03 0,04327244 ! histidine catabolic process GO:0006548 6 5 0,000 3,813E-03 0,04306928 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 3,813E-03 0,04286802 ! microvillus organization GO:0032528 7 5 0,000 3,813E-03 0,04266864 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 3,813E-03 0,0424711 ! L-serine biosynthetic process GO:0006564 6 5 0,000 3,813E-03 0,04227538 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,813E-03 0,04208145 ! tryptophan metabolic process GO:0006568 9 5 0,000 3,813E-03 0,0418893 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 3,813E-03 0,04169889 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,813E-03 0,04151021 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 3,813E-03 0,04132323 ! polyol catabolic process GO:0046174 7 5 0,000 3,813E-03 0,04113792 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 3,813E-03 0,04095427 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,813E-03 0,04077225 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,813E-03 0,04059184 ! muscle cell migration GO:0014812 8 5 0,000 3,813E-03 0,04041303 ! mitochondrial fission GO:0000266 8 5 0,000 3,813E-03 0,04023578 ! sister chromatid cohesion GO:0007062 12 5 0,000 3,813E-03 0,04006007 ! mRNA transcription GO:0009299 9 5 0,000 3,813E-03 0,0398859 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 3,813E-03 0,03971323 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 3,813E-03 0,03954206 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 3,813E-03 0,03937235 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,813E-03 0,03920409 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 3,813E-03 0,03903726 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 3,813E-03 0,03887185 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 3,813E-03 0,03870783 ! response to food GO:0032094 6 5 0,000 3,813E-03 0,0385452 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 3,813E-03 0,03838392 ! positive regulation of transporter activity GO:0032411 8 5 0,000 3,813E-03 0,03822399 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 3,813E-03 0,03806538 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,813E-03 0,03790809 ! paraxial mesoderm development GO:0048339 14 5 0,000 3,813E-03 0,03775209 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 3,813E-03 0,03759736 ! forebrain neuron development GO:0021884 13 5 0,000 3,813E-03 0,03744391 ! lipoprotein catabolic process GO:0042159 11 5 0,000 3,813E-03 0,03729169 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 3,813E-03 0,03714072 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 3,813E-03 0,03699095 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,813E-03 0,0368424 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 3,813E-03 0,03669503 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 3,813E-03 0,03654883 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,813E-03 0,0364038 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 3,813E-03 0,03625991 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 3,813E-03 0,03611715 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,813E-03 0,03597552 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 3,813E-03 0,03583499 ! basic amino acid transport GO:0015802 11 5 0,000 3,813E-03 0,03569555 ! cellular glucose homeostasis GO:0001678 5 5 0,000 3,813E-03 0,0355572 ! early endosome to late endosome transport GO:0045022 12 5 0,000 3,813E-03 0,03541991 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,813E-03 0,03528368 ! depyrimidination GO:0045008 10 5 0,000 3,813E-03 0,03514849 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 3,813E-03 0,03501434 ! regulation of centrosome cycle GO:0046605 7 5 0,000 3,813E-03 0,0348812 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 3,813E-03 0,03474908 ! zinc ion homeostasis GO:0055069 8 5 0,000 3,813E-03 0,03461795 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 3,813E-03 0,03448781 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 3,813E-03 0,03435864 ! forebrain morphogenesis GO:0048853 13 5 0,000 3,813E-03 0,03423044 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 3,813E-03 0,03410319 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 3,813E-03 0,03397688 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 3,813E-03 0,0338515 ! peptidyl-arginine modification GO:0018195 9 5 0,000 3,813E-03 0,03372705 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 3,813E-03 0,0336035 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,813E-03 0,03348086 ! response to arsenic GO:0046685 10 5 0,000 3,813E-03 0,03335912 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 3,813E-03 0,03323825 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 3,813E-03 0,03311826 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 3,813E-03 0,03299913 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 3,813E-03 0,03288085 ! response to cadmium ion GO:0046686 7 5 0,000 3,813E-03 0,03276342 ! bile acid biosynthetic process GO:0006699 6 5 0,000 3,813E-03 0,03264682 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 3,813E-03 0,03253105 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 3,813E-03 0,0324161 ! decidualization GO:0046697 11 5 0,000 3,813E-03 0,03230196 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 3,813E-03 0,03218862 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 3,813E-03 0,03207607 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,813E-03 0,03196431 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,813E-03 0,03185332 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 3,813E-03 0,0317431 ! base conversion or substitution editing GO:0016553 5 5 0,000 3,813E-03 0,03163364 ! neural tube patterning GO:0021532 7 5 0,000 3,813E-03 0,03152494 ! embryonic cleavage GO:0040016 6 5 0,000 3,813E-03 0,03141698 ! peroxisome fission GO:0016559 5 5 0,000 3,813E-03 0,03130975 ! histone demethylation GO:0016577 10 5 0,000 3,813E-03 0,03120325 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 3,813E-03 0,03109748 ! mitotic recombination GO:0006312 9 5 0,000 3,813E-03 0,03099242 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 3,813E-03 0,03088807 ! metaphase plate congression GO:0051310 7 5 0,000 3,813E-03 0,03078442 ! regulation of sterol transport GO:0032371 7 5 0,000 3,813E-03 0,03068146 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 3,813E-03 0,03057919 ! enteric nervous system development GO:0048484 8 5 0,000 3,813E-03 0,0304776 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 3,813E-03 0,03037668 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 3,813E-03 0,03027643 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 3,813E-03 0,03017683 ! muscle cell proliferation GO:0033002 11 5 0,000 3,813E-03 0,03007789 ! skeletal muscle regeneration GO:0043403 8 5 0,000 3,813E-03 0,0299796 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 3,813E-03 0,02988194 ! plasminogen activation GO:0031639 5 5 0,000 3,813E-03 0,02978492 ! B cell homeostasis GO:0001782 13 5 0,000 3,813E-03 0,02968853 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 3,813E-03 0,02959276 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 3,813E-03 0,02949761 ! metaphase GO:0051323 8 5 0,000 3,813E-03 0,02940307 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 3,813E-03 0,02930913 ! cellular response to nutrient GO:0031670 8 5 0,000 3,813E-03 0,02921579 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 3,813E-03 0,02912304 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,813E-03 0,02903088 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,813E-03 0,0289393 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 3,813E-03 0,02884829 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 3,813E-03 0,02875786 ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 3,813E-03 0,02866799 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 3,813E-03 0,02857868 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 3,813E-03 0,02848993 ! regulation of telomerase activity GO:0051972 6 5 0,000 3,813E-03 0,02840172 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,813E-03 0,02831406 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 3,813E-03 0,02822694 ! porphyrin catabolic process GO:0006787 12 5 0,000 3,813E-03 0,02814036 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 3,813E-03 0,0280543 ! striatum development GO:0021756 9 5 0,000 3,813E-03 0,02796877 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 3,813E-03 0,02788376 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 3,813E-03 0,02779926 ! glial cell migration GO:0008347 11 5 0,000 3,813E-03 0,02771528 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 3,813E-03 0,0276318 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 3,813E-03 0,02754882 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,813E-03 0,02746634 ! somatic stem cell maintenance GO:0035019 15 5 0,000 3,813E-03 0,02738435 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 3,813E-03 0,02730285 ! negative regulation of lipase activity GO:0060192 8 5 0,000 3,813E-03 0,02722183 ! neuroprotection GO:0043526 6 5 0,000 3,813E-03 0,02714129 ! neural plate development GO:0001840 8 5 0,000 3,813E-03 0,02706123 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 3,813E-03 0,02698164 ! regulation of sensory perception GO:0051931 7 5 0,000 3,813E-03 0,02690251 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 3,813E-03 0,02682385 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 3,813E-03 0,02674565 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 3,813E-03 0,0266679 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 3,813E-03 0,0265906 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 3,813E-03 0,02651375 ! sequestering of calcium ion GO:0051208 7 5 0,000 3,813E-03 0,02643734 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,813E-03 0,02636137 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 3,813E-03 0,02628584 ! spindle assembly GO:0051225 6 5 0,000 3,813E-03 0,02621073 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 3,813E-03 0,02613606 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 3,813E-03 0,02606181 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 3,813E-03 0,02598798 ! drug metabolic process GO:0017144 6 5 0,000 3,813E-03 0,02591457 ! stem cell division GO:0017145 11 5 0,000 3,813E-03 0,02584157 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 3,813E-03 0,02576898 ! organ regeneration GO:0031100 7 5 0,000 3,813E-03 0,0256968 ! carnitine metabolic process GO:0009437 7 5 0,000 3,813E-03 0,02562502 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 3,813E-03 0,02555364 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 3,813E-03 0,02548266 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 4,574E-03 0,03048335 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 4,574E-03 0,03039914 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 4,574E-03 0,0303154 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 4,574E-03 0,03023211 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 4,574E-03 0,03014928 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 4,574E-03 0,03006691 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 4,574E-03 0,02998498 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 4,574E-03 0,0299035 ! sleep GO:0030431 13 6 0,000 4,574E-03 0,02982246 ! response to oxygen radical GO:0000305 11 6 0,000 4,574E-03 0,02974186 ! positive regulation of axon extension GO:0045773 11 6 0,000 4,574E-03 0,02966169 ! myoblast cell fate commitment GO:0048625 16 6 0,000 4,574E-03 0,02958196 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 4,574E-03 0,02950265 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 4,574E-03 0,02942377 ! regulation of interferon-beta production GO:0032648 8 6 0,000 4,574E-03 0,0293453 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 4,574E-03 0,02926726 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 4,574E-03 0,02918963 ! forebrain regionalization GO:0021871 8 6 0,000 4,574E-03 0,0291124 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 4,574E-03 0,02903559 ! male meiosis GO:0007140 7 6 0,000 4,574E-03 0,02895918 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 4,574E-03 0,02888317 ! response to zinc ion GO:0010043 9 6 0,000 4,574E-03 0,02880756 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 4,574E-03 0,02873235 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 4,574E-03 0,02865752 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 4,574E-03 0,02858309 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 4,574E-03 0,02850904 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 4,574E-03 0,02843537 ! malate metabolic process GO:0006108 11 6 0,000 4,574E-03 0,02836208 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 4,574E-03 0,02828917 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 4,574E-03 0,02821664 ! protein refolding GO:0042026 15 6 0,000 4,574E-03 0,02814447 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 4,574E-03 0,02807268 ! opsonization GO:0008228 8 6 0,000 4,574E-03 0,02800124 ! mating behavior GO:0007617 7 6 0,000 4,574E-03 0,02793017 ! neuron remodeling GO:0016322 15 6 0,000 4,574E-03 0,02785947 ! erythrocyte maturation GO:0043249 7 6 0,000 4,574E-03 0,02778911 ! embryonic hemopoiesis GO:0035162 14 6 0,000 4,574E-03 0,02771912 ! equilibrioception GO:0050957 14 6 0,000 4,574E-03 0,02764947 ! protein amino acid dealkylation GO:0008214 12 6 0,000 4,574E-03 0,02758017 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 4,574E-03 0,02751122 ! photoreceptor cell development GO:0042461 10 6 0,000 4,574E-03 0,02744262 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 4,574E-03 0,02737435 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 4,574E-03 0,02730642 ! response to interferon-gamma GO:0034341 15 6 0,000 4,574E-03 0,02723883 ! toxin metabolic process GO:0009404 11 6 0,000 4,574E-03 0,02717158 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 4,574E-03 0,02710465 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 4,574E-03 0,02703806 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 4,574E-03 0,02697179 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 4,574E-03 0,02690584 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 4,574E-03 0,02684022 ! cGMP-mediated signaling GO:0019934 13 6 0,000 4,574E-03 0,02677491 ! activation of MAPKKK activity GO:0000185 12 6 0,000 4,574E-03 0,02670992 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 4,574E-03 0,02664525 ! thymic T cell selection GO:0045061 12 6 0,000 4,574E-03 0,02658089 ! protein lipoylation GO:0009249 10 6 0,000 4,574E-03 0,02651684 ! cysteine metabolic process GO:0006534 10 6 0,000 4,574E-03 0,0264531 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 4,574E-03 0,02638966 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 4,574E-03 0,02632653 ! glutamate catabolic process GO:0006538 10 6 0,000 4,574E-03 0,0262637 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 4,574E-03 0,02620116 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 4,574E-03 0,02613893 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 4,574E-03 0,02607699 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 4,574E-03 0,02601534 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 4,574E-03 0,02595398 ! hyperosmotic response GO:0006972 9 6 0,000 4,574E-03 0,02589291 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 4,574E-03 0,02583213 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 4,574E-03 0,02577164 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 4,574E-03 0,02571142 ! urea metabolic process GO:0019627 7 6 0,000 4,574E-03 0,02565149 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 4,574E-03 0,02559183 ! neutrophil activation GO:0042119 8 6 0,000 4,574E-03 0,02553246 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 4,574E-03 0,02547335 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 4,574E-03 0,02541452 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 4,574E-03 0,02535597 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 4,574E-03 0,02529768 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 4,574E-03 0,02523965 ! neuron apoptosis GO:0051402 9 6 0,000 4,574E-03 0,0251819 ! nucleoside salvage GO:0043174 9 6 0,000 4,574E-03 0,0251244 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 4,574E-03 0,02506717 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 4,574E-03 0,0250102 ! T cell mediated immunity GO:0002456 16 6 0,000 4,574E-03 0,02495349 ! negative regulation of platelet activation GO:0010544 9 6 0,000 4,574E-03 0,02489703 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 4,574E-03 0,02484083 ! carnitine transport GO:0015879 10 6 0,000 4,574E-03 0,02478488 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 4,574E-03 0,02472919 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,574E-03 0,02467374 ! positive regulation of exocytosis GO:0045921 8 6 0,000 4,574E-03 0,02461854 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 4,574E-03 0,02456359 ! 5S class rRNA transcription GO:0042791 11 6 0,000 4,574E-03 0,02450888 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 4,574E-03 0,02445442 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 4,574E-03 0,0244002 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 4,574E-03 0,02434621 ! sodium ion homeostasis GO:0055078 11 6 0,000 4,574E-03 0,02429247 ! establishment of spindle localization GO:0051293 12 6 0,000 4,574E-03 0,02423896 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 4,574E-03 0,02418569 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 4,574E-03 0,02413265 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 4,574E-03 0,02407984 ! neural nucleus development GO:0048857 14 6 0,000 4,574E-03 0,02402727 ! response to UV-C GO:0010225 11 6 0,000 4,574E-03 0,02397492 ! astrocyte development GO:0014002 15 6 0,000 4,574E-03 0,0239228 ! protein targeting to lysosome GO:0006622 10 6 0,000 4,574E-03 0,02387091 ! purine base biosynthetic process GO:0009113 17 6 0,000 4,574E-03 0,02381924 ! interaction with symbiont GO:0051702 13 6 0,000 4,574E-03 0,02376779 ! regulation of dendrite development GO:0050773 16 6 0,000 4,574E-03 0,02371657 ! skeletal muscle contraction GO:0003009 6 6 0,000 4,574E-03 0,02366557 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 4,574E-03 0,02361478 ! response to copper ion GO:0046688 10 6 0,000 4,574E-03 0,02356422 ! response to exogenous dsRNA GO:0043330 10 6 0,000 4,574E-03 0,02351387 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 4,574E-03 0,02346373 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,574E-03 0,02341381 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 4,574E-03 0,0233641 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 4,574E-03 0,02331459 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 4,574E-03 0,0232653 ! regulation of dopamine secretion GO:0014059 14 6 0,000 4,574E-03 0,02321622 ! nucleoside catabolic process GO:0009164 7 6 0,000 4,574E-03 0,02316734 ! hair follicle maturation GO:0048820 7 6 0,000 4,574E-03 0,02311867 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 4,574E-03 0,02307021 ! Schwann cell development GO:0014044 15 6 0,000 4,574E-03 0,02302194 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 4,574E-03 0,02297388 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 4,574E-03 0,02292602 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 4,574E-03 0,02287836 ! subpallium development GO:0021544 10 6 0,000 4,574E-03 0,02283089 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 4,574E-03 0,02278362 ! histone ubiquitination GO:0016574 8 6 0,000 4,574E-03 0,02273655 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 4,574E-03 0,02268967 ! maintenance of organ identity GO:0048496 9 6 0,000 4,574E-03 0,02264298 ! G2 phase GO:0051319 16 6 0,000 4,574E-03 0,02259649 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 4,574E-03 0,02255018 ! establishment of planar polarity GO:0001736 7 6 0,000 4,574E-03 0,02250407 ! regulation of mast cell activation GO:0033003 12 6 0,000 4,574E-03 0,02245814 ! membrane to membrane docking GO:0022614 14 6 0,000 4,574E-03 0,0224124 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 4,574E-03 0,02236685 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 4,574E-03 0,02232148 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 4,574E-03 0,02227629 ! receptor internalization GO:0031623 10 6 0,000 4,574E-03 0,02223129 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 4,574E-03 0,02218647 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 4,574E-03 0,02214183 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,574E-03 0,02209737 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 4,574E-03 0,02205308 ! protein deubiquitination GO:0016579 14 6 0,000 4,574E-03 0,02200898 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 4,574E-03 0,02196505 ! protein destabilization GO:0031648 9 6 0,000 4,574E-03 0,02192129 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 4,574E-03 0,02187771 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 4,574E-03 0,0218343 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 4,574E-03 0,02179107 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 4,574E-03 0,021748 ! progesterone metabolic process GO:0042448 10 6 0,000 4,574E-03 0,02170511 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 4,574E-03 0,02166238 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 4,574E-03 0,02161982 ! negative regulation of axon extension GO:0030517 21 6 0,000 4,574E-03 0,02157743 ! removal of superoxide radicals GO:0019430 11 6 0,000 4,574E-03 0,0215352 ! triglyceride catabolic process GO:0019433 10 6 0,000 4,574E-03 0,02149314 ! determination of adult lifespan GO:0008340 15 6 0,000 4,574E-03 0,02145125 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 4,574E-03 0,02140951 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 4,574E-03 0,02136794 ! cerebellar cortex formation GO:0021697 8 6 0,000 4,574E-03 0,02132653 ! catecholamine transport GO:0051937 9 6 0,000 4,574E-03 0,02128528 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 4,574E-03 0,02124419 ! sensory cilium assembly GO:0035058 10 6 0,000 4,574E-03 0,02120325 ! organ or tissue specific immune response GO:0002251 7 6 0,000 4,574E-03 0,02116248 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 4,574E-03 0,02112186 ! maternal placenta development GO:0001893 12 6 0,000 4,574E-03 0,0210814 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 4,574E-03 0,02104109 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 4,574E-03 0,02100093 ! negative regulation of B cell activation GO:0050869 13 6 0,000 4,574E-03 0,02096093 ! protein amino acid prenylation GO:0018346 16 6 0,000 4,574E-03 0,02092108 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 4,574E-03 0,02088138 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 4,574E-03 0,02084183 ! positive regulation of coagulation GO:0050820 12 6 0,000 4,574E-03 0,02080244 ! tRNA transcription GO:0009304 14 7 0,000 5,334E-03 0,02421487 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 5,334E-03 0,02416927 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 5,334E-03 0,02412384 ! behavioral response to cocaine GO:0048148 14 7 0,000 5,334E-03 0,02407858 ! regulation of helicase activity GO:0051095 15 7 0,000 5,334E-03 0,02403349 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 5,334E-03 0,02398857 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 5,334E-03 0,02394381 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 5,334E-03 0,02389922 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 5,334E-03 0,0238548 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 5,334E-03 0,02381054 ! prostate gland development GO:0030850 13 7 0,000 5,334E-03 0,02376645 ! nucleotide-sugar transport GO:0015780 12 7 0,000 5,334E-03 0,02372252 ! synaptonemal complex assembly GO:0007130 10 7 0,000 5,334E-03 0,02367875 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 5,334E-03 0,02363514 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 5,334E-03 0,0235917 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 5,334E-03 0,02354841 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 5,334E-03 0,02350528 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 5,334E-03 0,02346231 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 5,334E-03 0,0234195 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 5,334E-03 0,02337684 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 5,334E-03 0,02333433 ! SMAD protein complex assembly GO:0007183 12 7 0,000 5,334E-03 0,02329198 ! glycolipid transport GO:0046836 10 7 0,000 5,334E-03 0,02324979 ! protein amino acid sulfation GO:0006477 10 7 0,000 5,334E-03 0,02320775 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 5,334E-03 0,02316585 ! neuron adhesion GO:0007158 12 7 0,000 5,334E-03 0,02312411 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 5,334E-03 0,02308252 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 5,334E-03 0,02304108 ! actin-myosin filament sliding GO:0033275 11 7 0,000 5,334E-03 0,02299979 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 5,334E-03 0,02295865 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 5,334E-03 0,02291765 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 5,334E-03 0,0228768 ! mRNA stabilization GO:0048255 18 7 0,000 5,334E-03 0,02283609 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 5,334E-03 0,02279553 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 5,334E-03 0,02275511 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 5,334E-03 0,02271484 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 5,334E-03 0,02267471 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 5,334E-03 0,02263471 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 5,334E-03 0,02259486 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 5,334E-03 0,02255516 ! lipoprotein transport GO:0042953 14 7 0,000 5,334E-03 0,02251558 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 5,334E-03 0,02247615 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 5,334E-03 0,02243686 ! rhythmic behavior GO:0007622 15 7 0,000 5,334E-03 0,0223977 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 5,334E-03 0,02235868 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 5,334E-03 0,0223198 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 5,334E-03 0,02228105 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 5,334E-03 0,02224243 ! regulation of odontogenesis GO:0042481 13 7 0,000 5,334E-03 0,02220395 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 5,334E-03 0,0221656 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 5,334E-03 0,02212738 ! mechanosensory behavior GO:0007638 14 7 0,000 5,334E-03 0,0220893 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 5,334E-03 0,02205135 ! positive regulation of isotype switching GO:0045830 15 7 0,000 5,334E-03 0,02201352 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 5,334E-03 0,02197583 ! protein-cofactor linkage GO:0018065 13 7 0,000 5,334E-03 0,02193826 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 5,334E-03 0,02190082 ! spinal cord patterning GO:0021511 13 7 0,000 5,334E-03 0,02186351 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 5,334E-03 0,02182633 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 5,334E-03 0,02178928 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 5,334E-03 0,02175234 ! adrenal gland development GO:0030325 17 7 0,000 5,334E-03 0,02171554 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 5,334E-03 0,02167886 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 5,334E-03 0,0216423 ! ovulation GO:0030728 9 7 0,000 5,334E-03 0,02160586 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 5,334E-03 0,02156955 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 5,334E-03 0,02153336 ! microtubule nucleation GO:0007020 20 7 0,000 5,334E-03 0,02149729 ! proline biosynthetic process GO:0006561 10 7 0,000 5,334E-03 0,02146134 ! thyroid hormone generation GO:0006590 13 7 0,000 5,334E-03 0,02142551 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 5,334E-03 0,02138981 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 5,334E-03 0,02135422 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 5,334E-03 0,02131874 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 5,334E-03 0,02128339 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 5,334E-03 0,02124815 ! galactose metabolic process GO:0006012 13 7 0,000 5,334E-03 0,02121303 ! vesicle fusion GO:0006906 17 7 0,000 5,334E-03 0,02117803 ! response to dietary excess GO:0002021 8 7 0,000 5,334E-03 0,02114314 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 5,334E-03 0,02110836 ! intracellular pH reduction GO:0051452 11 7 0,000 5,334E-03 0,0210737 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 5,334E-03 0,02103915 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 5,334E-03 0,02100472 ! organ growth GO:0035265 15 7 0,000 5,334E-03 0,0209704 ! purine salvage GO:0043101 10 7 0,000 5,334E-03 0,02093619 ! nucleoside transport GO:0015858 8 7 0,000 5,334E-03 0,02090209 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 5,334E-03 0,0208681 ! parturition GO:0007567 14 7 0,000 5,334E-03 0,02083423 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 5,334E-03 0,02080046 ! rRNA modification GO:0000154 14 7 0,000 5,334E-03 0,0207668 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 5,334E-03 0,02073325 ! spindle checkpoint GO:0031577 15 7 0,000 5,334E-03 0,02069981 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 5,334E-03 0,02066648 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 5,334E-03 0,02063325 ! macrophage differentiation GO:0030225 11 7 0,000 5,334E-03 0,02060013 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 5,334E-03 0,02056712 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 5,334E-03 0,02053421 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 5,334E-03 0,02050141 ! hyaluronan metabolic process GO:0030212 8 7 0,000 5,334E-03 0,02046871 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 5,334E-03 0,02043612 ! anterograde axon cargo transport GO:0008089 18 7 0,000 5,334E-03 0,02040363 ! fibrinolysis GO:0042730 10 7 0,000 5,334E-03 0,02037124 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 5,334E-03 0,02033896 ! eating behavior GO:0042755 7 7 0,000 5,334E-03 0,02030678 ! B cell lineage commitment GO:0002326 21 7 0,000 5,334E-03 0,0202747 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 5,334E-03 0,02024272 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 5,334E-03 0,02021084 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 5,334E-03 0,02017906 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 5,334E-03 0,02014738 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 5,334E-03 0,0201158 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 5,334E-03 0,02008432 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 5,334E-03 0,02005294 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 5,334E-03 0,02002166 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 5,334E-03 0,01999047 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 5,334E-03 0,01995938 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 5,334E-03 0,01992839 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 5,334E-03 0,01989749 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 5,334E-03 0,01986669 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 5,334E-03 0,01983599 ! regulation of meiosis GO:0040020 12 7 0,000 5,334E-03 0,01980538 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 5,334E-03 0,01977486 ! T cell lineage commitment GO:0002360 16 7 0,000 5,334E-03 0,01974444 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 5,334E-03 0,01971411 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 5,334E-03 0,01968387 ! oxygen homeostasis GO:0032364 12 7 0,000 5,334E-03 0,01965373 ! transcription termination GO:0006353 13 7 0,000 5,334E-03 0,01962367 ! response to tumor cell GO:0002347 13 7 0,000 5,334E-03 0,01959371 ! regulation of respiratory burst GO:0060263 11 7 0,000 5,334E-03 0,01956385 ! coenzyme A metabolic process GO:0015936 12 7 0,000 5,334E-03 0,01953407 ! anaphase GO:0051322 17 7 0,000 5,334E-03 0,01950438 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 5,334E-03 0,01947478 ! axonal fasciculation GO:0007413 18 7 0,000 5,334E-03 0,01944528 ! negative regulation of nuclear division GO:0051784 14 7 0,000 5,334E-03 0,01941586 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 5,334E-03 0,01938653 ! peptidyl-threonine modification GO:0018210 25 7 0,000 5,334E-03 0,01935729 ! diuresis GO:0030146 12 7 0,000 5,334E-03 0,01932814 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 5,334E-03 0,01929907 ! thiamin metabolic process GO:0006772 7 7 0,000 5,334E-03 0,0192701 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 5,334E-03 0,0192412 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 5,334E-03 0,0192124 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 5,334E-03 0,01918368 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 5,334E-03 0,01915505 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 5,334E-03 0,0191265 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 5,334E-03 0,01909804 ! melanin biosynthetic process GO:0042438 8 7 0,000 5,334E-03 0,01906966 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 5,334E-03 0,01904137 ! dopamine biosynthetic process GO:0042416 18 7 0,000 5,334E-03 0,01901316 ! glycolipid catabolic process GO:0019377 15 7 0,000 5,334E-03 0,01898503 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 5,334E-03 0,01895699 ! lymph node development GO:0048535 10 7 0,000 5,334E-03 0,01892903 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 5,334E-03 0,01890115 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 5,334E-03 0,01887336 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 5,334E-03 0,01884564 ! endosome to lysosome transport GO:0008333 11 7 0,000 5,334E-03 0,01881801 ! protein modification by small protein removal GO:0070646 16 7 0,000 5,334E-03 0,01879046 ! adult feeding behavior GO:0008343 9 7 0,000 5,334E-03 0,01876299 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 5,334E-03 0,0187356 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 5,334E-03 0,01870828 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 5,334E-03 0,01868105 ! muscle adaptation GO:0043500 14 7 0,000 5,334E-03 0,0186539 ! embryonic heart tube development GO:0035050 10 7 0,000 5,334E-03 0,01862683 ! retina homeostasis GO:0001895 12 7 0,000 5,334E-03 0,01859983 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 5,334E-03 0,01857291 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 5,334E-03 0,01854607 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 5,334E-03 0,01851931 ! protein prenylation GO:0018342 18 7 0,000 5,334E-03 0,01849263 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 5,334E-03 0,01846602 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 5,334E-03 0,01843949 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 5,334E-03 0,01841303 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 6,094E-03 0,02100565 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 6,094E-03 0,0209756 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 6,094E-03 0,02094563 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 6,094E-03 0,02091575 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 6,094E-03 0,02088596 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 6,094E-03 0,02085625 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 6,094E-03 0,02082662 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 6,094E-03 0,02079708 ! neutral lipid catabolic process GO:0046461 13 8 0,000 6,094E-03 0,02076762 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 6,094E-03 0,02073825 ! meiotic prophase I GO:0007128 13 8 0,000 6,094E-03 0,02070896 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 6,094E-03 0,02067975 ! oligopeptide transport GO:0006857 15 8 0,000 6,094E-03 0,02065062 ! UTP metabolic process GO:0046051 8 8 0,000 6,094E-03 0,02062158 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 6,094E-03 0,02059261 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 6,094E-03 0,02056373 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 6,094E-03 0,02053493 ! macrophage chemotaxis GO:0048246 12 8 0,000 6,094E-03 0,02050621 ! succinate metabolic process GO:0006105 14 8 0,000 6,094E-03 0,02047757 ! membrane hyperpolarization GO:0060081 10 8 0,000 6,094E-03 0,02044901 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 6,094E-03 0,02042053 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 6,094E-03 0,02039213 ! T-helper 1 type immune response GO:0042088 12 8 0,000 6,094E-03 0,02036381 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 6,094E-03 0,02033556 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 6,094E-03 0,0203074 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,094E-03 0,02027931 ! ganglioside metabolic process GO:0001573 19 8 0,000 6,094E-03 0,0202513 ! reflex GO:0060004 16 8 0,000 6,094E-03 0,02022337 ! negative regulation of endocytosis GO:0045806 11 8 0,000 6,094E-03 0,02019551 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 6,094E-03 0,02016773 ! endothelial cell differentiation GO:0045446 17 8 0,000 6,094E-03 0,02014003 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 6,094E-03 0,0201124 ! glycerolipid catabolic process GO:0046503 13 8 0,000 6,094E-03 0,02008485 ! hemoglobin metabolic process GO:0020027 13 8 0,000 6,094E-03 0,02005737 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 6,094E-03 0,02002997 ! pigment granule organization GO:0048753 16 8 0,000 6,094E-03 0,02000265 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 6,094E-03 0,0199754 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 6,094E-03 0,01994822 ! astrocyte differentiation GO:0048708 18 8 0,000 6,094E-03 0,01992112 ! histidine metabolic process GO:0006547 16 8 0,000 6,094E-03 0,01989409 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 6,094E-03 0,01986713 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 6,094E-03 0,01984025 ! glycine catabolic process GO:0006546 13 8 0,000 6,094E-03 0,01981343 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 6,094E-03 0,0197867 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 6,094E-03 0,01976003 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 6,094E-03 0,01973343 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 6,094E-03 0,01970691 ! regulation of pigmentation during development GO:0048070 24 8 0,000 6,094E-03 0,01968046 ! melanin metabolic process GO:0006582 15 8 0,000 6,094E-03 0,01965408 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 6,094E-03 0,01962777 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 6,094E-03 0,01960153 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 6,094E-03 0,01957536 ! macrophage activation GO:0042116 12 8 0,000 6,094E-03 0,01954925 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 6,094E-03 0,01952322 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 6,094E-03 0,01949726 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 6,094E-03 0,01947137 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 6,094E-03 0,01944555 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 6,094E-03 0,01941979 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 6,094E-03 0,0193941 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,094E-03 0,01936848 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 6,094E-03 0,01934293 ! osteoblast development GO:0002076 16 8 0,000 6,094E-03 0,01931745 ! positive regulation of vasodilation GO:0045909 13 8 0,000 6,094E-03 0,01929203 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 6,094E-03 0,01926668 ! negative regulation of translational initiation GO:0045947 10 8 0,000 6,094E-03 0,01924139 ! Schwann cell differentiation GO:0014037 19 8 0,000 6,094E-03 0,01921617 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 6,094E-03 0,01919102 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 6,094E-03 0,01916594 ! response to UV-B GO:0010224 16 8 0,000 6,094E-03 0,01914092 ! protein targeting to vacuole GO:0006623 12 8 0,000 6,094E-03 0,01911596 ! protein retention in ER lumen GO:0006621 14 8 0,000 6,094E-03 0,01909107 ! intermediate filament organization GO:0045109 12 8 0,000 6,094E-03 0,01906624 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 6,094E-03 0,01904148 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 6,094E-03 0,01901678 ! cellular extravasation GO:0045123 12 8 0,000 6,094E-03 0,01899215 ! cardiac muscle cell development GO:0055013 13 8 0,000 6,094E-03 0,01896758 ! regulation of circadian rhythm GO:0042752 16 8 0,000 6,094E-03 0,01894308 ! response to antibiotic GO:0046677 11 8 0,000 6,094E-03 0,01891863 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 6,094E-03 0,01889425 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 6,094E-03 0,01886994 ! response to tropane GO:0014073 15 8 0,000 6,094E-03 0,01884568 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 6,094E-03 0,01882149 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 6,094E-03 0,01879736 ! melanosome transport GO:0032402 13 8 0,000 6,094E-03 0,01877329 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 6,094E-03 0,01874929 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 6,094E-03 0,01872534 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 6,094E-03 0,01870146 ! mast cell activation GO:0045576 14 8 0,000 6,094E-03 0,01867763 ! multicellular organismal aging GO:0010259 18 8 0,000 6,094E-03 0,01865387 ! dendrite morphogenesis GO:0048813 13 8 0,000 6,094E-03 0,01863017 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 6,094E-03 0,01860652 ! nucleosome disassembly GO:0006337 14 8 0,000 6,094E-03 0,01858294 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 6,094E-03 0,01855942 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 6,094E-03 0,01853596 ! leukocyte activation during immune response GO:0002366 13 8 0,000 6,094E-03 0,01851255 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 6,094E-03 0,01848921 ! establishment of chromosome localization GO:0051303 12 8 0,000 6,094E-03 0,01846592 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 6,094E-03 0,01844269 ! intracellular lipid transport GO:0032365 13 8 0,000 6,094E-03 0,01841952 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 6,094E-03 0,01839641 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 6,094E-03 0,01837336 ! regulation of macrophage activation GO:0043030 15 8 0,000 6,094E-03 0,01835036 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 6,094E-03 0,01832743 ! positive regulation of epidermis development GO:0045684 13 8 0,000 6,094E-03 0,01830455 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 6,094E-03 0,01828172 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 6,094E-03 0,01825896 ! hormone catabolic process GO:0042447 17 8 0,000 6,094E-03 0,01823625 ! positive regulation of glucose import GO:0046326 8 8 0,000 6,094E-03 0,01821359 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 6,094E-03 0,01819099 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 6,094E-03 0,01816845 ! ATP catabolic process GO:0006200 11 8 0,000 6,094E-03 0,01814597 ! blastocyst growth GO:0001832 19 8 0,000 6,094E-03 0,01812354 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 6,094E-03 0,01810116 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 6,094E-03 0,01807884 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 6,094E-03 0,01805658 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 6,094E-03 0,01803437 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 6,094E-03 0,01801221 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 6,094E-03 0,01799011 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 6,094E-03 0,01796807 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 6,094E-03 0,01794607 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 6,094E-03 0,01792413 ! amino sugar catabolic process GO:0046348 10 8 0,000 6,094E-03 0,01790225 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 6,094E-03 0,01788042 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 6,094E-03 0,01785864 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 6,094E-03 0,01783691 ! behavioral response to nicotine GO:0035095 12 8 0,000 6,094E-03 0,01781524 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 6,094E-03 0,01779362 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 6,094E-03 0,01777205 ! NAD biosynthetic process GO:0009435 13 8 0,000 6,094E-03 0,01775053 ! regulation of developmental growth GO:0048638 15 9 0,000 6,853E-03 0,01993792 ! axon extension GO:0048675 15 9 0,000 6,853E-03 0,01991384 ! autophagic vacuole formation GO:0000045 15 9 0,000 6,853E-03 0,01988982 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 6,853E-03 0,01986586 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 6,853E-03 0,01984195 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 6,853E-03 0,0198181 ! pentose-phosphate shunt GO:0006098 16 9 0,000 6,853E-03 0,01979431 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 6,853E-03 0,01977058 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 6,853E-03 0,0197469 ! cell proliferation in forebrain GO:0021846 15 9 0,000 6,853E-03 0,01972328 ! phosphate transport GO:0006817 19 9 0,000 6,853E-03 0,01969972 ! reproductive behavior GO:0019098 19 9 0,000 6,853E-03 0,01967621 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 6,853E-03 0,01965276 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 6,853E-03 0,01962936 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 6,853E-03 0,01960602 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 6,853E-03 0,01958274 ! GTP metabolic process GO:0046039 9 9 0,000 6,853E-03 0,01955951 ! RNA methylation GO:0001510 15 9 0,000 6,853E-03 0,01953633 ! elastic fiber assembly GO:0048251 15 9 0,000 6,853E-03 0,01951321 ! induction of positive chemotaxis GO:0050930 15 9 0,000 6,853E-03 0,01949015 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 6,853E-03 0,01946713 ! artery development GO:0060840 24 9 0,000 6,853E-03 0,01944418 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 6,853E-03 0,01942128 ! regulation of glycolysis GO:0006110 21 9 0,000 6,853E-03 0,01939843 ! cerebral cortex cell migration GO:0021795 15 9 0,000 6,853E-03 0,01937563 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 6,853E-03 0,01935289 ! chemosensory behavior GO:0007635 20 9 0,000 6,853E-03 0,0193302 ! microtubule bundle formation GO:0001578 21 9 0,000 6,853E-03 0,01930757 ! middle ear morphogenesis GO:0042474 14 9 0,000 6,853E-03 0,01928499 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 6,853E-03 0,01926246 ! leukocyte degranulation GO:0043299 16 9 0,000 6,853E-03 0,01923998 ! bile acid and bile salt transport GO:0015721 13 9 0,000 6,853E-03 0,01921756 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 6,853E-03 0,01919518 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 6,853E-03 0,01917286 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 6,853E-03 0,0191506 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 6,853E-03 0,01912838 ! protein targeting to ER GO:0045047 22 9 0,000 6,853E-03 0,01910621 ! ceramide biosynthetic process GO:0046513 19 9 0,000 6,853E-03 0,0190841 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 6,853E-03 0,01906204 ! T cell selection GO:0045058 23 9 0,000 6,853E-03 0,01904003 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 6,853E-03 0,01901807 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 6,853E-03 0,01899616 ! phosphagen metabolic process GO:0006599 12 9 0,000 6,853E-03 0,0189743 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 6,853E-03 0,01895249 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 6,853E-03 0,01893073 ! regulation of type I interferon production GO:0032479 12 9 0,000 6,853E-03 0,01890902 ! mannose metabolic process GO:0006013 13 9 0,000 6,853E-03 0,01888736 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 6,853E-03 0,01886575 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 6,853E-03 0,01884419 ! Rac protein signal transduction GO:0016601 17 9 0,000 6,853E-03 0,01882267 ! receptor clustering GO:0043113 18 9 0,000 6,853E-03 0,01880121 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 6,853E-03 0,0187798 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 6,853E-03 0,01875843 ! ruffle organization GO:0031529 15 9 0,000 6,853E-03 0,01873712 ! retinol metabolic process GO:0042572 18 9 0,000 6,853E-03 0,01871585 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 6,853E-03 0,01869463 ! behavioral fear response GO:0001662 22 9 0,000 6,853E-03 0,01867346 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 6,853E-03 0,01865233 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 6,853E-03 0,01863126 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 6,853E-03 0,01861023 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 6,853E-03 0,01858925 ! oligodendrocyte development GO:0014003 10 9 0,000 6,853E-03 0,01856831 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 6,853E-03 0,01854743 ! segment specification GO:0007379 13 9 0,000 6,853E-03 0,01852659 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 6,853E-03 0,01850579 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 6,853E-03 0,01848505 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 6,853E-03 0,01846435 ! response to amine stimulus GO:0014075 13 9 0,000 6,853E-03 0,01844369 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 6,853E-03 0,01842309 ! erythrocyte development GO:0048821 15 9 0,000 6,853E-03 0,01840253 ! gas homeostasis GO:0033483 16 9 0,000 6,853E-03 0,01838201 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 6,853E-03 0,01836154 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 6,853E-03 0,01834112 ! renal water homeostasis GO:0003091 14 9 0,000 6,853E-03 0,01832074 ! postreplication repair GO:0006301 22 9 0,000 6,853E-03 0,0183004 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 6,853E-03 0,01828011 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 6,853E-03 0,01825987 ! icosanoid secretion GO:0032309 15 9 0,000 6,853E-03 0,01823967 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 6,853E-03 0,01821952 ! cerebellum morphogenesis GO:0021587 14 9 0,000 6,853E-03 0,01819941 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 6,853E-03 0,01817934 ! regulation of cell division GO:0051302 15 9 0,000 6,853E-03 0,01815932 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 6,853E-03 0,01813934 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 6,853E-03 0,01811941 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 6,853E-03 0,01809952 ! sterol catabolic process GO:0016127 11 9 0,000 6,853E-03 0,01807967 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 6,853E-03 0,01805987 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 6,853E-03 0,01804011 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 6,853E-03 0,0180204 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 6,853E-03 0,01800072 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 6,853E-03 0,01798109 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 6,853E-03 0,01796151 ! musculoskeletal movement GO:0050881 14 9 0,000 6,853E-03 0,01794196 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 6,853E-03 0,01792246 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 6,853E-03 0,017903 ! regulation of synaptogenesis GO:0051963 15 9 0,000 6,853E-03 0,01788358 ! purine base metabolic process GO:0006144 21 9 0,000 6,853E-03 0,01786421 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 6,853E-03 0,01784487 ! pigment granule transport GO:0051904 17 9 0,000 6,853E-03 0,01782558 ! regulation of fibrinolysis GO:0051917 16 9 0,000 6,853E-03 0,01780633 ! regulation of telomere maintenance GO:0032204 14 9 0,000 6,853E-03 0,01778712 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 6,853E-03 0,01776796 ! regulation of muscle adaptation GO:0043502 14 9 0,000 6,853E-03 0,01774883 ! regulation of amino acid transport GO:0051955 11 9 0,000 6,853E-03 0,01772975 ! mitochondrion localization GO:0051646 15 9 0,000 6,853E-03 0,0177107 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 7,612E-03 0,01965027 ! negative regulation of blood pressure GO:0045776 26 10 0,000 7,612E-03 0,01962921 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 7,612E-03 0,01960819 ! synapsis GO:0007129 13 10 0,000 7,612E-03 0,01958722 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 7,612E-03 0,01956629 ! N-glycan processing GO:0006491 20 10 0,000 7,612E-03 0,01954541 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 7,612E-03 0,01952457 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 7,612E-03 0,01950378 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 7,612E-03 0,01948303 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 7,612E-03 0,01946233 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 7,612E-03 0,01944167 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 7,612E-03 0,01942105 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 7,612E-03 0,01940048 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 7,612E-03 0,01937995 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 7,612E-03 0,01935946 ! androgen metabolic process GO:0008209 17 10 0,000 7,612E-03 0,01933902 ! phospholipid efflux GO:0033700 16 10 0,000 7,612E-03 0,01931862 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 7,612E-03 0,01929826 ! positive regulation of heart contraction GO:0045823 16 10 0,000 7,612E-03 0,01927795 ! lung alveolus development GO:0048286 26 10 0,000 7,612E-03 0,01925768 ! pathogenesis GO:0009405 13 10 0,000 7,612E-03 0,01923745 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 7,612E-03 0,01921726 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 7,612E-03 0,01919712 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 7,612E-03 0,01917702 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 7,612E-03 0,01915696 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 7,612E-03 0,01913694 ! endoderm development GO:0007492 16 10 0,000 7,612E-03 0,01911696 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 7,612E-03 0,01909703 ! arginine catabolic process GO:0006527 13 10 0,000 7,612E-03 0,01907714 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 7,612E-03 0,01905728 ! proline metabolic process GO:0006560 13 10 0,000 7,612E-03 0,01903747 ! glucan biosynthetic process GO:0009250 14 10 0,000 7,612E-03 0,01901771 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 7,612E-03 0,01899798 ! polyamine biosynthetic process GO:0006596 12 10 0,000 7,612E-03 0,01897829 ! V(D)J recombination GO:0033151 28 10 0,000 7,612E-03 0,01895864 ! reverse cholesterol transport GO:0043691 16 10 0,000 7,612E-03 0,01893904 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 7,612E-03 0,01891947 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 7,612E-03 0,01889995 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 7,612E-03 0,01888046 ! regulation of sodium ion transport GO:0002028 21 10 0,000 7,612E-03 0,01886102 ! multicellular organism growth GO:0035264 18 10 0,000 7,612E-03 0,01884162 ! phagocytosis, engulfment GO:0006911 28 10 0,000 7,612E-03 0,01882225 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 7,612E-03 0,01880293 ! epithelial cell development GO:0002064 20 10 0,000 7,612E-03 0,01878364 ! lens development in camera-type eye GO:0002088 16 10 0,000 7,612E-03 0,0187644 ! retinoic acid metabolic process GO:0042573 14 10 0,000 7,612E-03 0,01874519 ! macroautophagy GO:0016236 17 10 0,000 7,612E-03 0,01872602 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 7,612E-03 0,0187069 ! positive regulation of translational initiation GO:0045948 11 10 0,000 7,612E-03 0,01868781 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 7,612E-03 0,01866876 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 7,612E-03 0,01864975 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 7,612E-03 0,01863077 ! copper ion homeostasis GO:0055070 13 10 0,000 7,612E-03 0,01861184 ! regulation of bone resorption GO:0045124 25 10 0,000 7,612E-03 0,01859294 ! regulation of gliogenesis GO:0014013 23 10 0,000 7,612E-03 0,01857409 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 7,612E-03 0,01855527 ! alpha-beta T cell activation GO:0046631 23 10 0,000 7,612E-03 0,01853649 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 7,612E-03 0,01851775 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 7,612E-03 0,01849904 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 7,612E-03 0,01848037 ! blastoderm segmentation GO:0007350 18 10 0,000 7,612E-03 0,01846174 ! response to dsRNA GO:0043331 20 10 0,000 7,612E-03 0,01844315 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 7,612E-03 0,0184246 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 7,612E-03 0,01840608 ! melanosome localization GO:0032400 16 10 0,000 7,612E-03 0,0183876 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 7,612E-03 0,01836916 ! regulation of B cell differentiation GO:0045577 19 10 0,000 7,612E-03 0,01835075 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 7,612E-03 0,01833238 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 7,612E-03 0,01831405 ! mRNA cleavage GO:0006379 17 10 0,000 7,612E-03 0,01829575 ! protein sumoylation GO:0016925 15 10 0,000 7,612E-03 0,0182775 ! hindbrain morphogenesis GO:0021575 19 10 0,000 7,612E-03 0,01825927 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 7,612E-03 0,01824109 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 7,612E-03 0,01822294 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 7,612E-03 0,01820482 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 7,612E-03 0,01818674 ! salivary gland development GO:0007431 27 10 0,000 7,612E-03 0,0181687 ! prophase GO:0051324 15 10 0,000 7,612E-03 0,01815069 ! negative regulation of neurological system process GO:0031645 19 10 0,000 7,612E-03 0,01813272 ! apical protein localization GO:0045176 15 10 0,000 7,612E-03 0,01811479 ! ubiquinone metabolic process GO:0006743 15 10 0,000 7,612E-03 0,01809689 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 7,612E-03 0,01807902 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 7,612E-03 0,01806119 ! midbrain development GO:0030901 13 10 0,000 7,612E-03 0,0180434 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 7,612E-03 0,01802564 ! methionine biosynthetic process GO:0009086 19 10 0,000 7,612E-03 0,01800792 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 7,612E-03 0,01799023 ! quaternary ammonium group transport GO:0015697 21 10 0,000 7,612E-03 0,01797257 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 7,612E-03 0,01795495 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 7,612E-03 0,01793737 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 7,612E-03 0,01791981 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 7,612E-03 0,0179023 ! oocyte development GO:0048599 17 10 0,000 7,612E-03 0,01788481 ! establishment of pigment granule localization GO:0051905 18 10 0,000 7,612E-03 0,01786737 ! blastocyst formation GO:0001825 17 10 0,000 7,612E-03 0,01784995 ! cerebellar cortex development GO:0021695 15 10 0,000 7,612E-03 0,01783257 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 7,612E-03 0,01781522 ! activation of innate immune response GO:0002218 12 10 0,000 7,612E-03 0,01779791 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 7,612E-03 0,01778063 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 7,612E-03 0,01776339 ! response to nicotine GO:0035094 20 10 0,000 7,612E-03 0,01774617 ! establishment of cell polarity GO:0030010 16 10 0,000 7,612E-03 0,01772899 ! negative regulation of immune effector process GO:0002698 20 10 0,000 7,612E-03 0,01771185 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 7,612E-03 0,01769473 ! localization within membrane GO:0051668 20 10 0,000 7,612E-03 0,01767765 ! negative regulation of muscle development GO:0048635 20 11 0,000 8,37E-03 0,01941958 ! respiratory burst GO:0045730 17 11 0,000 8,37E-03 0,01940087 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 8,37E-03 0,0193822 ! neuron fate specification GO:0048665 17 11 0,000 8,37E-03 0,01936356 ! telencephalon cell migration GO:0022029 20 11 0,000 8,37E-03 0,01934496 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 8,37E-03 0,0193264 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 8,37E-03 0,01930787 ! thyroid gland development GO:0030878 26 11 0,000 8,37E-03 0,01928937 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 8,37E-03 0,01927091 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 8,37E-03 0,01925249 ! Golgi vesicle budding GO:0048194 22 11 0,000 8,37E-03 0,0192341 ! response to pain GO:0048265 24 11 0,000 8,37E-03 0,01921575 ! detection of mechanical stimulus GO:0050982 22 11 0,000 8,37E-03 0,01919743 ! T cell proliferation GO:0042098 26 11 0,000 8,37E-03 0,01917915 ! blood vessel remodeling GO:0001974 29 11 0,000 8,37E-03 0,0191609 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 8,37E-03 0,01914268 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 8,37E-03 0,01912451 ! bone resorption GO:0045453 16 11 0,000 8,37E-03 0,01910636 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 8,37E-03 0,01908825 ! ventral spinal cord development GO:0021517 21 11 0,000 8,37E-03 0,01907017 ! negative regulation of proteolysis GO:0045861 25 11 0,000 8,37E-03 0,01905213 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 8,37E-03 0,01903412 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 8,37E-03 0,01901615 ! melanocyte differentiation GO:0030318 21 11 0,000 8,37E-03 0,01899821 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 8,37E-03 0,01898031 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 8,37E-03 0,01896243 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 8,37E-03 0,01894459 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 8,37E-03 0,01892679 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 8,37E-03 0,01890902 ! lipid digestion GO:0044241 18 11 0,000 8,37E-03 0,01889128 ! substrate-bound cell migration GO:0006929 13 11 0,000 8,37E-03 0,01887357 ! UV protection GO:0009650 19 11 0,000 8,37E-03 0,0188559 ! adult heart development GO:0007512 14 11 0,000 8,37E-03 0,01883826 ! chondrocyte differentiation GO:0002062 24 11 0,000 8,37E-03 0,01882066 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 8,37E-03 0,01880308 ! temperature homeostasis GO:0001659 17 11 0,000 8,37E-03 0,01878554 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 8,37E-03 0,01876804 ! negative regulation of ossification GO:0030279 26 11 0,000 8,37E-03 0,01875056 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 8,37E-03 0,01873312 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 8,37E-03 0,01871571 ! regulation of organ growth GO:0046620 13 11 0,000 8,37E-03 0,01869833 ! pigment granule localization GO:0051875 20 11 0,000 8,37E-03 0,01868099 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 8,37E-03 0,01866367 ! vasoconstriction GO:0042310 18 11 0,000 8,37E-03 0,01864639 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 8,37E-03 0,01862914 ! embryonic axis specification GO:0000578 18 11 0,000 8,37E-03 0,01861193 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 8,37E-03 0,01859474 ! snRNA metabolic process GO:0016073 24 11 0,000 8,37E-03 0,01857759 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 8,37E-03 0,01856046 ! nitric oxide metabolic process GO:0046209 15 11 0,000 8,37E-03 0,01854337 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 8,37E-03 0,01852631 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 8,37E-03 0,01850929 ! zymogen activation GO:0031638 15 11 0,000 8,37E-03 0,01849229 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 8,37E-03 0,01847532 ! neuroblast proliferation GO:0007405 24 11 0,000 8,37E-03 0,01845839 ! nucleosome positioning GO:0016584 15 11 0,000 8,37E-03 0,01844149 ! regulation of isotype switching GO:0045191 22 11 0,000 8,37E-03 0,01842461 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 8,37E-03 0,01840777 ! glutathione biosynthetic process GO:0006750 13 11 0,000 8,37E-03 0,01839096 ! regulation of leukocyte migration GO:0002685 26 11 0,000 8,37E-03 0,01837418 ! acid secretion GO:0046717 18 11 0,000 8,37E-03 0,01835743 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 8,37E-03 0,01834071 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 8,37E-03 0,01832403 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 8,37E-03 0,01830737 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 8,37E-03 0,01829074 ! oocyte differentiation GO:0009994 18 11 0,000 8,37E-03 0,01827414 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 8,37E-03 0,01825757 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 8,37E-03 0,01824104 ! cholesterol efflux GO:0033344 19 11 0,000 8,37E-03 0,01822453 ! anterior/posterior axis specification GO:0009948 18 11 0,000 8,37E-03 0,01820805 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 8,37E-03 0,0181916 ! negative regulation of glucose import GO:0046325 17 11 0,000 8,37E-03 0,01817518 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 8,37E-03 0,0181588 ! embryonic gut development GO:0048566 15 11 0,000 8,37E-03 0,01814244 ! regulation of organic acid transport GO:0032890 18 11 0,000 8,37E-03 0,01812611 ! cardiac cell differentiation GO:0035051 31 11 0,000 8,37E-03 0,01810981 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 8,37E-03 0,01809353 ! defense response to fungus GO:0050832 13 11 0,000 8,37E-03 0,01807729 ! developmental induction GO:0031128 19 11 0,000 8,37E-03 0,01806108 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 8,37E-03 0,0180449 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 8,37E-03 0,01802874 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 8,37E-03 0,01801262 ! sequestering of metal ion GO:0051238 14 11 0,000 8,37E-03 0,01799652 ! lamellipodium assembly GO:0030032 20 11 0,000 8,37E-03 0,01798045 ! regulation of embryonic development GO:0045995 27 11 0,000 8,37E-03 0,01796441 ! nucleus localization GO:0051647 19 11 0,000 8,37E-03 0,0179484 ! regulation of synapse organization GO:0050807 17 11 0,000 8,37E-03 0,01793242 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 9,128E-03 0,0195381 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 9,128E-03 0,01952073 ! positive regulation of blood pressure GO:0045777 17 12 0,000 9,128E-03 0,0195034 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 9,128E-03 0,01948609 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 9,128E-03 0,01946882 ! virus-host interaction GO:0019048 29 12 0,000 9,128E-03 0,01945157 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 9,128E-03 0,01943436 ! cartilage condensation GO:0001502 20 12 0,000 9,128E-03 0,01941717 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 9,128E-03 0,01940002 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 9,128E-03 0,0193829 ! protein complex disassembly GO:0043241 27 12 0,000 9,128E-03 0,01936581 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 9,128E-03 0,01934874 ! regulation of cell projection assembly GO:0060491 30 12 0,000 9,128E-03 0,01933171 ! hippocampus development GO:0021766 26 12 0,000 9,128E-03 0,01931471 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 9,128E-03 0,01929774 ! cytokine biosynthetic process GO:0042089 21 12 0,000 9,128E-03 0,01928079 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 9,128E-03 0,01926388 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 9,128E-03 0,019247 ! regulation of exit from mitosis GO:0007096 17 12 0,000 9,128E-03 0,01923014 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 9,128E-03 0,01921332 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 9,128E-03 0,01919652 ! drug transport GO:0015893 16 12 0,000 9,128E-03 0,01917976 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 9,128E-03 0,01916302 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 9,128E-03 0,01914632 ! tyrosine metabolic process GO:0006570 16 12 0,000 9,128E-03 0,01912964 ! polyamine metabolic process GO:0006595 17 12 0,000 9,128E-03 0,01911299 ! focal adhesion formation GO:0048041 35 12 0,000 9,128E-03 0,01909637 ! mitotic spindle organization GO:0007052 21 12 0,000 9,128E-03 0,01907978 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 9,128E-03 0,01906322 ! forebrain cell migration GO:0021885 21 12 0,000 9,128E-03 0,01904668 ! asymmetric protein localization GO:0008105 20 12 0,000 9,128E-03 0,01903018 ! membrane protein proteolysis GO:0033619 25 12 0,000 9,128E-03 0,0190137 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 9,128E-03 0,01899725 ! entry into host cell GO:0030260 32 12 0,000 9,128E-03 0,01898083 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 9,128E-03 0,01896444 ! monoamine transport GO:0015844 18 12 0,000 9,128E-03 0,01894808 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 9,128E-03 0,01893175 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 9,128E-03 0,01891544 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 9,128E-03 0,01889916 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 9,128E-03 0,01888291 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 9,128E-03 0,01886669 ! protein targeting to peroxisome GO:0006625 23 12 0,000 9,128E-03 0,01885049 ! protein homotetramerization GO:0051289 21 12 0,000 9,128E-03 0,01883433 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 9,128E-03 0,01881819 ! regulation of phagocytosis GO:0050764 16 12 0,000 9,128E-03 0,01880208 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 9,128E-03 0,01878599 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 9,128E-03 0,01876994 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 9,128E-03 0,01875391 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 9,128E-03 0,0187379 ! cranial nerve development GO:0021545 20 12 0,000 9,128E-03 0,01872193 ! fucose catabolic process GO:0019317 22 12 0,000 9,128E-03 0,01870598 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 9,128E-03 0,01869006 ! histone acetylation GO:0016573 26 12 0,000 9,128E-03 0,01867417 ! histone methylation GO:0016571 26 12 0,000 9,128E-03 0,0186583 ! mRNA polyadenylation GO:0006378 23 12 0,000 9,128E-03 0,01864247 ! autonomic nervous system development GO:0048483 24 12 0,000 9,128E-03 0,01862665 ! gland morphogenesis GO:0022612 29 12 0,000 9,128E-03 0,01861087 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 9,128E-03 0,01859511 ! peptidyl-lysine modification GO:0018205 21 12 0,000 9,128E-03 0,01857938 ! T cell homeostasis GO:0043029 25 12 0,000 9,128E-03 0,01856367 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 9,128E-03 0,01854799 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 9,128E-03 0,01853234 ! spleen development GO:0048536 22 12 0,000 9,128E-03 0,01851672 ! digestive tract morphogenesis GO:0048546 26 12 0,000 9,128E-03 0,01850112 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 9,128E-03 0,01848554 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 9,128E-03 0,01847 ! regulation of RNA splicing GO:0043484 20 12 0,000 9,128E-03 0,01845447 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 9,128E-03 0,01843898 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 9,128E-03 0,01842351 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 9,128E-03 0,01840807 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 9,128E-03 0,01839265 ! response to cold GO:0009409 17 12 0,000 9,128E-03 0,01837726 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 9,128E-03 0,01836189 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 9,128E-03 0,01834655 ! cGMP metabolic process GO:0046068 18 13 0,000 9,885E-03 0,0198516 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 9,885E-03 0,01983504 ! regulation of chemokine production GO:0032642 18 13 0,000 9,885E-03 0,01981851 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 9,885E-03 0,01980201 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 9,885E-03 0,01978553 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 9,885E-03 0,01976909 ! lipid localization GO:0010876 28 13 0,000 9,885E-03 0,01975267 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 9,885E-03 0,01973628 ! organelle fusion GO:0048284 32 13 0,000 9,885E-03 0,01971991 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 9,885E-03 0,01970357 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 9,885E-03 0,01968726 ! pseudouridine synthesis GO:0001522 17 13 0,000 9,885E-03 0,01967098 ! endocrine pancreas development GO:0031018 22 13 0,000 9,885E-03 0,01965472 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 9,885E-03 0,01963849 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 9,885E-03 0,01962229 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 9,885E-03 0,01960611 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 9,885E-03 0,01958996 ! methionine metabolic process GO:0006555 27 13 0,000 9,885E-03 0,01957384 ! plasma membrane organization GO:0007009 24 13 0,000 9,885E-03 0,01955774 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 9,885E-03 0,01954167 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 9,885E-03 0,01952563 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 9,885E-03 0,01950961 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 9,885E-03 0,01949362 ! cell-cell junction assembly GO:0007043 27 13 0,000 9,885E-03 0,01947765 ! response to X-ray GO:0010165 25 13 0,000 9,885E-03 0,01946171 ! cytokine metabolic process GO:0042107 22 13 0,000 9,885E-03 0,0194458 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 9,885E-03 0,01942991 ! exocrine system development GO:0035272 32 13 0,000 9,885E-03 0,01941405 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 9,885E-03 0,01939822 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 9,885E-03 0,01938241 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 9,885E-03 0,01936662 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 9,885E-03 0,01935086 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 9,885E-03 0,01933513 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 9,885E-03 0,01931943 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 9,885E-03 0,01930374 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 9,885E-03 0,01928809 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 9,885E-03 0,01927246 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 9,885E-03 0,01925685 ! regulation of cellular pH GO:0030641 22 13 0,000 9,885E-03 0,01924127 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 9,885E-03 0,01922572 ! ribosome assembly GO:0042255 17 13 0,000 9,885E-03 0,01921019 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 9,885E-03 0,01919468 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 9,885E-03 0,0191792 ! chromatin silencing GO:0006342 26 13 0,000 9,885E-03 0,01916375 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 9,885E-03 0,01914832 ! regulation of epidermis development GO:0045682 19 13 0,000 9,885E-03 0,01913291 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 9,885E-03 0,01911753 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 9,885E-03 0,01910218 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 9,885E-03 0,01908685 ! regulation of mRNA stability GO:0043488 31 13 0,000 9,885E-03 0,01907154 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 9,885E-03 0,01905626 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 9,885E-03 0,019041 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 9,885E-03 0,01902577 ! mRNA 3'-end processing GO:0031124 24 13 0,000 9,885E-03 0,01901056 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 9,885E-03 0,01899538 ! embryonic placenta development GO:0001892 23 13 0,000 9,885E-03 0,01898022 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 9,885E-03 0,01896508 ! insulin secretion GO:0030073 23 13 0,000 9,885E-03 0,01894997 ! actin filament polymerization GO:0030041 24 13 0,000 9,885E-03 0,01893488 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 9,885E-03 0,01891982 ! acrosome reaction GO:0007340 18 13 0,000 9,885E-03 0,01890478 ! rRNA transcription GO:0009303 25 14 0,000 0,01064101 0,0203354 ! lactation GO:0007595 26 14 0,000 0,01064101 0,02031926 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01064101 0,02030315 ! reproductive cellular process GO:0048610 20 14 0,000 0,01064101 0,02028706 ! tRNA modification GO:0006400 20 14 0,000 0,01064101 0,020271 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01064101 0,02025496 ! regulation of S phase GO:0033261 23 14 0,000 0,01064101 0,02023895 ! water transport GO:0006833 21 14 0,000 0,01064101 0,02022296 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01064101 0,020207 ! non-recombinational repair GO:0000726 25 14 0,000 0,01064101 0,02019106 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01064101 0,02017515 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01064101 0,02015927 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01064101 0,02014341 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01064101 0,02012757 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01064101 0,02011176 ! palate development GO:0060021 31 14 0,000 0,01064101 0,02009597 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01064101 0,02008021 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01064101 0,02006448 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01064101 0,02004876 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01064101 0,02003308 ! arginine metabolic process GO:0006525 17 14 0,000 0,01064101 0,02001741 ! regulation of heart rate GO:0002027 24 14 0,000 0,01064101 0,02000177 ! organic alcohol transport GO:0015850 29 14 0,000 0,01064101 0,01998616 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01064101 0,01997057 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01064101 0,019955 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01064101 0,01993946 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01064101 0,01992395 ! L-amino acid transport GO:0015807 30 14 0,000 0,01064101 0,01990845 ! bone mineralization GO:0030282 17 14 0,000 0,01064101 0,01989298 ! stem cell development GO:0048864 43 14 0,000 0,01064101 0,01987754 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01064101 0,01986212 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01064101 0,01984672 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01064101 0,01983135 ! cerebellum development GO:0021549 21 14 0,000 0,01064101 0,019816 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01064101 0,01980067 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01064101 0,01978537 ! response to gamma radiation GO:0010332 28 14 0,000 0,01064101 0,01977009 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01064101 0,01975484 ! cofactor transport GO:0051181 26 14 0,000 0,01064101 0,01973961 ! NADP metabolic process GO:0006739 24 14 0,000 0,01064101 0,0197244 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01064101 0,01970922 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01064101 0,01969405 ! intestinal absorption GO:0050892 25 14 0,000 0,01064101 0,01967892 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01064101 0,0196638 ! oxygen transport GO:0015671 21 14 0,000 0,01064101 0,01964871 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01064101 0,01963364 ! male genitalia development GO:0030539 24 14 0,000 0,01064101 0,0196186 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01064101 0,01960358 ! regulation of axon extension GO:0030516 37 14 0,000 0,01064101 0,01958858 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01064101 0,0195736 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01139692 0,02094805 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01139692 0,02093206 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,01139692 0,02091609 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01139692 0,02090015 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01139692 0,02088423 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01139692 0,02086834 ! copper ion transport GO:0006825 20 15 0,000 0,01139692 0,02085247 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01139692 0,02083662 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01139692 0,0208208 ! sulfate transport GO:0008272 23 15 0,000 0,01139692 0,02080501 ! response to cAMP GO:0051591 22 15 0,000 0,01139692 0,02078923 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01139692 0,02077348 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01139692 0,02075776 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01139692 0,02074206 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01139692 0,02072638 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01139692 0,02071072 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01139692 0,02069509 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01139692 0,02067949 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01139692 0,0206639 ! pituitary gland development GO:0021983 29 15 0,000 0,01139692 0,02064834 ! vesicle coating GO:0006901 33 15 0,000 0,01139692 0,0206328 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01139692 0,02061729 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01139692 0,0206018 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01139692 0,02058633 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01139692 0,02057089 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01139692 0,02055547 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01139692 0,02054007 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01139692 0,0205247 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01139692 0,02050935 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01139692 0,02049402 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01139692 0,02047871 ! histone deacetylation GO:0016575 20 15 0,000 0,01139692 0,02046343 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01139692 0,02044817 ! tissue regeneration GO:0042246 26 15 0,000 0,01139692 0,02043293 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01139692 0,02041772 ! water homeostasis GO:0030104 27 15 0,000 0,01139692 0,02040253 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01139692 0,02038736 ! muscle maintenance GO:0046716 26 15 0,000 0,01139692 0,02037221 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01139692 0,02035709 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01139692 0,02034199 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01139692 0,02032691 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01139692 0,02031185 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01139692 0,02029682 ! cell killing GO:0001906 29 15 0,000 0,01139692 0,0202818 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01139692 0,02026681 ! detection of bacterium GO:0016045 18 15 0,000 0,01139692 0,02025184 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01139692 0,0202369 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01139692 0,02022197 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01139692 0,02020707 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01139692 0,02019219 ! peptide hormone processing GO:0016486 23 15 0,000 0,01139692 0,02017733 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01215228 0,02149882 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01215228 0,02148302 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01215228 0,02146725 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01215228 0,0214515 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01215228 0,02143577 ! bone remodeling GO:0046849 27 16 0,000 0,01215228 0,02142007 ! filopodium assembly GO:0046847 32 16 0,000 0,01215228 0,02140439 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01215228 0,02138873 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01215228 0,0213731 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01215228 0,02135748 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01215228 0,02134189 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01215228 0,02132633 ! startle response GO:0001964 28 16 0,000 0,01215228 0,02131078 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01215228 0,02129526 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01215228 0,02127976 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01215228 0,02126429 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01215228 0,02124883 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01215228 0,0212334 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01215228 0,02121799 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01215228 0,02120261 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01215228 0,02118724 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01215228 0,0211719 ! response to osmotic stress GO:0006970 25 16 0,000 0,01215228 0,02115658 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01215228 0,02114128 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01215228 0,02112601 ! fructose metabolic process GO:0006000 25 16 0,000 0,01215228 0,02111076 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01215228 0,02109552 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,01215228 0,02108031 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01215228 0,02106513 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01215228 0,02104996 ! axon cargo transport GO:0008088 43 16 0,000 0,01215228 0,02103482 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01215228 0,0210197 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01215228 0,02100459 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01215228 0,02098952 ! DNA replication initiation GO:0006270 27 16 0,000 0,01215228 0,02097446 ! neuron recognition GO:0008038 35 16 0,000 0,01215228 0,02095942 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01215228 0,02094441 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01215228 0,02092942 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01215228 0,02091445 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01215228 0,0208995 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01215228 0,02088457 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01215228 0,02086966 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01215228 0,02085478 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01215228 0,02083991 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01215228 0,02082507 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01215228 0,02081025 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01215228 0,02079545 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01215228 0,02078067 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01215228 0,02076591 ! defense response to virus GO:0051607 37 16 0,000 0,01215228 0,02075117 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01290709 0,02202444 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01290709 0,02200883 ! metencephalon development GO:0022037 30 17 0,000 0,01290709 0,02199325 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01290709 0,02197768 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01290709 0,02196214 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01290709 0,02194662 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01290709 0,02193112 ! signal complex assembly GO:0007172 41 17 0,000 0,01290709 0,02191564 ! endothelial cell migration GO:0043542 28 17 0,000 0,01290709 0,02190019 ! inositol metabolic process GO:0006020 28 17 0,000 0,01290709 0,02188475 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01290709 0,02186934 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01290709 0,02185395 ! glial cell development GO:0021782 27 17 0,000 0,01290709 0,02183858 ! limbic system development GO:0021761 36 17 0,000 0,01290709 0,02182324 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01290709 0,02180791 ! adult walking behavior GO:0007628 33 17 0,000 0,01290709 0,02179261 ! heart looping GO:0001947 30 17 0,000 0,01290709 0,02177733 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01290709 0,02176206 ! myoblast differentiation GO:0045445 45 17 0,000 0,01290709 0,02174682 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01290709 0,02173161 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01290709 0,02171641 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01290709 0,02170123 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01290709 0,02168608 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01290709 0,02167095 ! glycine metabolic process GO:0006544 28 17 0,000 0,01290709 0,02165583 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01290709 0,02164074 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01290709 0,02162567 ! NAD metabolic process GO:0019674 29 17 0,000 0,01290709 0,02161062 ! membrane budding GO:0006900 37 17 0,000 0,01290709 0,02159559 ! DNA integration GO:0015074 29 17 0,000 0,01290709 0,02158059 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01290709 0,0215656 ! regulation of protein binding GO:0043393 33 17 0,000 0,01290709 0,02155064 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01290709 0,02153569 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01290709 0,02152077 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01290709 0,02150586 ! genitalia development GO:0048806 30 17 0,000 0,01290709 0,02149098 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01290709 0,02147612 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01290709 0,02146128 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01290709 0,02144645 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01290709 0,02143165 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01290709 0,02141687 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01290709 0,02140211 ! steroid catabolic process GO:0006706 31 17 0,000 0,01290709 0,02138737 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01290709 0,02137265 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01290709 0,02135795 ! gas transport GO:0015669 25 17 0,000 0,01290709 0,02134328 ! organic cation transport GO:0015695 31 17 0,000 0,01290709 0,02132862 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01290709 0,02131398 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01290709 0,02129936 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01290709 0,02128476 ! microspike assembly GO:0030035 36 17 0,000 0,01290709 0,02127018 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01290709 0,02125562 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01290709 0,02124108 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01366135 0,02246699 ! neuron maturation GO:0042551 42 18 0,000 0,01366135 0,02245164 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01366135 0,02243632 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01366135 0,02242102 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01366135 0,02240573 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01366135 0,02239047 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01366135 0,02237523 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01366135 0,02236001 ! memory GO:0007613 31 18 0,000 0,01366135 0,0223448 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01366135 0,02232962 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01366135 0,02231447 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01366135 0,02229933 ! centrosome cycle GO:0007098 25 18 0,000 0,01366135 0,02228421 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01366135 0,02226911 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01366135 0,02225403 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01366135 0,02223898 ! response to retinoic acid GO:0032526 26 18 0,000 0,01366135 0,02222394 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01366135 0,02220892 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01366135 0,02219393 ! response to fungus GO:0009620 21 18 0,000 0,01366135 0,02217895 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01366135 0,022164 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01366135 0,02214906 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01366135 0,02213415 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01366135 0,02211925 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01366135 0,02210438 ! vitamin transport GO:0051180 27 18 0,000 0,01366135 0,02208952 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01366135 0,02207469 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01366135 0,02205987 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01366135 0,02204508 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01366135 0,0220303 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01366135 0,02201554 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01366135 0,02200081 ! nerve development GO:0021675 28 18 0,000 0,01366135 0,02198609 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01366135 0,0219714 ! protein secretion GO:0009306 39 19 0,000 0,01441506 0,02316809 ! positive regulation of translation GO:0045727 30 19 0,000 0,01441506 0,02315262 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01441506 0,02313717 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01441506 0,02312175 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01441506 0,02310635 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,01441506 0,02309096 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01441506 0,0230756 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01441506 0,02306026 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01441506 0,02304493 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01441506 0,02302963 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01441506 0,02301435 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01441506 0,02299909 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01441506 0,02298385 ! cerebral cortex development GO:0021987 36 19 0,000 0,01441506 0,02296863 ! pigmentation during development GO:0048066 41 19 0,000 0,01441506 0,02295342 ! response to vitamin A GO:0033189 27 19 0,000 0,01441506 0,02293824 ! heme metabolic process GO:0042168 36 19 0,000 0,01441506 0,02292308 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01441506 0,02290794 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01441506 0,02289282 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01441506 0,02287772 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01441506 0,02286264 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,01441506 0,02284758 ! peptide cross-linking GO:0018149 37 19 0,000 0,01441506 0,02283254 ! protein export from nucleus GO:0006611 36 19 0,000 0,01441506 0,02281752 ! heart process GO:0003015 30 19 0,000 0,01441506 0,02280251 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01441506 0,02278753 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01441506 0,02277257 ! visual learning GO:0008542 36 19 0,000 0,01441506 0,02275763 ! cellular pigmentation GO:0033059 36 19 0,000 0,01441506 0,0227427 ! G1 phase GO:0051318 40 19 0,000 0,01441506 0,0227278 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01441506 0,02271292 ! cell-cell junction organization GO:0045216 35 19 0,000 0,01441506 0,02269805 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01441506 0,02268321 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01441506 0,02266838 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01441506 0,02265358 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01441506 0,02263879 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01441506 0,02262402 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01441506 0,02260927 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01441506 0,02259454 ! cilium assembly GO:0042384 37 19 0,000 0,01441506 0,02257983 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01441506 0,02256514 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01516821 0,02372868 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01516821 0,02371326 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01516821 0,02369787 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01516821 0,02368249 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01516821 0,02366713 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01516821 0,02365179 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01516821 0,02363647 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01516821 0,02362117 ! response to vitamin GO:0033273 31 20 0,000 0,01516821 0,0236059 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01516821 0,02359064 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01516821 0,0235754 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01516821 0,02356018 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01516821 0,02354498 ! response to alkaloid GO:0043279 38 20 0,000 0,01516821 0,0235298 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01516821 0,02351464 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01516821 0,02349949 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01516821 0,02348437 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01516821 0,02346927 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01516821 0,02345419 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01516821 0,02343912 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01516821 0,02342408 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01516821 0,02340905 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01516821 0,02339405 ! body fluid secretion GO:0007589 31 20 0,000 0,01516821 0,02337906 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01516821 0,02336409 ! peptide secretion GO:0002790 35 20 0,000 0,01516821 0,02334915 ! stem cell differentiation GO:0048863 53 20 0,000 0,01516821 0,02333422 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01516821 0,02331931 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01516821 0,02330442 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01516821 0,02328954 ! sensory perception of pain GO:0019233 30 20 0,000 0,01516821 0,02327469 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01516821 0,02325986 ! diencephalon development GO:0021536 34 20 0,000 0,01516821 0,02324504 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01516821 0,02323024 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01516821 0,02321547 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01516821 0,02320071 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01516821 0,02318597 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01516821 0,02317125 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01516821 0,02315654 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01516821 0,02314186 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01516821 0,0231272 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01516821 0,02311255 ! regulation of glucose import GO:0046324 29 20 0,000 0,01516821 0,02309792 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01516821 0,02308331 ! actin filament-based movement GO:0030048 43 20 0,000 0,01516821 0,02306872 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01516821 0,02305415 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01516821 0,02303959 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01516821 0,02302506 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01516821 0,02301054 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01516821 0,02299604 ! regulation of cell killing GO:0031341 42 21 0,000 0,01592081 0,02412184 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01592081 0,02410666 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01592081 0,0240915 ! hormone secretion GO:0046879 38 21 0,000 0,01592081 0,02407635 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01592081 0,02406123 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01592081 0,02404613 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01592081 0,02403104 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01592081 0,02401598 ! axis specification GO:0009798 38 21 0,000 0,01592081 0,02400093 ! ovarian follicle development GO:0001541 35 21 0,000 0,01592081 0,0239859 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01592081 0,02397089 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01592081 0,0239559 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01592081 0,02394093 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01592081 0,02392597 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01592081 0,02391104 ! cell aging GO:0007569 44 21 0,000 0,01592081 0,02389612 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01592081 0,02388122 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01592081 0,02386634 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01592081 0,02385148 ! cytolysis GO:0019835 24 21 0,000 0,01592081 0,02383664 ! vasodilation GO:0042311 39 21 0,000 0,01592081 0,02382182 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01592081 0,02380701 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01592081 0,02379222 ! oogenesis GO:0048477 36 21 0,000 0,01592081 0,02377746 ! DNA modification GO:0006304 34 21 0,000 0,01592081 0,0237627 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01592081 0,02374797 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01592081 0,02373326 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01592081 0,02371856 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01592081 0,02370389 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01592081 0,02368923 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01592081 0,02367459 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01592081 0,02365996 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01592081 0,02364536 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01592081 0,02363077 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01592081 0,0236162 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01592081 0,02360165 ! collagen catabolic process GO:0030574 28 21 0,000 0,01592081 0,02358712 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01592081 0,0235726 ! gut development GO:0048565 39 21 0,000 0,01592081 0,02355811 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01667287 0,02465576 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01667287 0,02464062 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01667287 0,02462549 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01667287 0,02461038 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01667287 0,02459529 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01667287 0,02458022 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01667287 0,02456517 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01667287 0,02455014 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01667287 0,02453512 ! regeneration GO:0031099 41 22 0,000 0,01667287 0,02452012 ! keratinization GO:0031424 28 22 0,000 0,01667287 0,02450515 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01667287 0,02449018 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01667287 0,02447524 ! sensory perception of taste GO:0050909 28 22 0,000 0,01667287 0,02446032 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01667287 0,02444541 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01667287 0,02443053 ! vacuolar transport GO:0007034 36 22 0,000 0,01667287 0,02441566 ! lysosome organization GO:0007040 41 22 0,000 0,01667287 0,0244008 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01667287 0,02438597 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01667287 0,02437116 ! fucose metabolic process GO:0006004 39 22 0,000 0,01667287 0,02435636 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01667287 0,02434158 ! ureteric bud development GO:0001657 43 22 0,000 0,01667287 0,02432682 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01667287 0,02431207 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01667287 0,02429735 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01667287 0,02428264 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01667287 0,02426795 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01667287 0,02425328 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01667287 0,02423862 ! sarcomere organization GO:0045214 30 22 0,000 0,01667287 0,02422399 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01667287 0,02420937 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01667287 0,02419477 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01667287 0,02418018 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01667287 0,02416562 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01667287 0,02415107 ! protein stabilization GO:0050821 39 22 0,000 0,01667287 0,02413654 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01742437 0,02520929 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01742437 0,02519414 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01742437 0,025179 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01742437 0,02516389 ! gluconeogenesis GO:0006094 33 23 0,000 0,01742437 0,0251488 ! viral genome replication GO:0019079 41 23 0,000 0,01742437 0,02513372 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01742437 0,02511866 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01742437 0,02510362 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01742437 0,02508859 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01742437 0,02507359 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01742437 0,0250586 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01742437 0,02504363 ! visual behavior GO:0007632 42 23 0,000 0,01742437 0,02502868 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01742437 0,02501375 ! response to ethanol GO:0045471 46 23 0,000 0,01742437 0,02499883 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01742437 0,02498393 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01742437 0,02496905 ! peroxisome organization GO:0007031 37 23 0,000 0,01742437 0,02495419 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01742437 0,02493935 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01742437 0,02492452 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01742437 0,02490971 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01742437 0,02489492 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01742437 0,02488014 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01742437 0,02486539 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01742437 0,02485065 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01742437 0,02483593 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01742437 0,02482122 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01742437 0,02480653 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01742437 0,02479186 ! fatty acid transport GO:0015908 44 23 0,000 0,01742437 0,02477721 ! platelet activation GO:0030168 37 23 0,000 0,01742437 0,02476258 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01742437 0,02474796 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01742437 0,02473336 ! hormone transport GO:0009914 40 23 0,000 0,01742437 0,02471877 ! cell-cell recognition GO:0009988 25 23 0,000 0,01742437 0,02470421 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01742437 0,02468966 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01742437 0,02467513 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01742437 0,02466061 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01742437 0,02464612 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01742437 0,02463163 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01817533 0,02567812 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01817533 0,02566305 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01817533 0,025648 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,01817533 0,02563297 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01817533 0,02561795 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01817533 0,02560295 ! vesicle docking GO:0048278 47 24 0,000 0,01817533 0,02558797 ! spinal cord development GO:0021510 47 24 0,000 0,01817533 0,02557301 ! vacuole organization GO:0007033 43 24 0,000 0,01817533 0,02555806 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01817533 0,02554313 ! digestive system process GO:0022600 39 24 0,000 0,01817533 0,02552822 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01817533 0,02551333 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01817533 0,02549845 ! regulation of behavior GO:0050795 43 24 0,000 0,01817533 0,02548359 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01817533 0,02546875 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01817533 0,02545392 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01817533 0,02543912 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01817533 0,02542433 ! membrane depolarization GO:0051899 39 24 0,000 0,01817533 0,02540955 ! pallium development GO:0021543 49 24 0,000 0,01817533 0,0253948 ! pentose metabolic process GO:0019321 35 24 0,000 0,01817533 0,02538006 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01817533 0,02536534 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01817533 0,02535063 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01817533 0,02533594 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01817533 0,02532127 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01817533 0,02530662 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01817533 0,02529198 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01817533 0,02527736 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01817533 0,02526276 ! regulation of amine transport GO:0051952 40 24 0,000 0,01817533 0,02524818 ! protein tetramerization GO:0051262 52 24 0,000 0,01817533 0,02523361 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,01892573 0,02626027 ! myelination GO:0042552 45 25 0,000 0,01892573 0,02624514 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,01892573 0,02623002 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,01892573 0,02621492 ! phototransduction GO:0007602 33 25 0,000 0,01892573 0,02619984 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,01892573 0,02618477 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,01892573 0,02616972 ! sperm motility GO:0030317 31 25 0,000 0,01892573 0,02615469 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,01892573 0,02613968 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,01892573 0,02612468 ! receptor metabolic process GO:0043112 46 25 0,000 0,01892573 0,0261097 ! response to starvation GO:0042594 42 25 0,000 0,01892573 0,02609474 ! osteoblast differentiation GO:0001649 60 25 0,000 0,01892573 0,02607979 ! neural crest cell development GO:0014032 54 25 0,000 0,01892573 0,02606486 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,01892573 0,02604995 ! negative regulation of cell development GO:0010721 73 25 0,000 0,01892573 0,02603506 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,01892573 0,02602018 ! interaction with host GO:0051701 62 25 0,000 0,01892573 0,02600532 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,01892573 0,02599048 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,01892573 0,02597565 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,01892573 0,02596084 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,01892573 0,02594605 ! immunoglobulin production GO:0002377 55 25 0,000 0,01892573 0,02593127 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,01892573 0,02591651 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,01892573 0,02590177 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,01892573 0,02588705 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,01892573 0,02587234 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,01892573 0,02585765 ! telomere organization GO:0032200 43 25 0,000 0,01892573 0,02584297 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,01892573 0,02582831 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,01892573 0,02581367 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,01967559 0,02682123 ! embryonic pattern specification GO:0009880 44 26 0,000 0,01967559 0,02680604 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,01967559 0,02679087 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,01967559 0,02677572 ! initiation of viral infection GO:0019059 57 26 0,000 0,01967559 0,02676058 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,01967559 0,02674547 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,01967559 0,02673036 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,01967559 0,02671528 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,01967559 0,02670021 ! molting cycle process GO:0022404 50 26 0,000 0,01967559 0,02668516 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,01967559 0,02667013 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,01967559 0,02665511 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,01967559 0,02664011 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,01967559 0,02662513 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,01967559 0,02661016 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,01967559 0,02659521 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,01967559 0,02658028 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,01967559 0,02656536 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,01967559 0,02655046 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,01967559 0,02653558 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,01967559 0,02652071 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,01967559 0,02650586 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,01967559 0,02649103 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,01967559 0,02647622 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,01967559 0,02646142 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,01967559 0,02644663 ! blastocyst development GO:0001824 49 26 0,000 0,01967559 0,02643187 ! leukocyte proliferation GO:0070661 52 26 0,000 0,01967559 0,02641712 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,01967559 0,02640238 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,01967559 0,02638767 ! neuron fate commitment GO:0048663 48 27 0,000 0,0204249 0,02737733 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,0204249 0,02736209 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0204249 0,02734686 ! iron ion transport GO:0006826 59 27 0,000 0,0204249 0,02733165 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,0204249 0,02731646 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0204249 0,02730128 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0204249 0,02728613 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0204249 0,02727098 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0204249 0,02725586 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0204249 0,02724075 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0204249 0,02722566 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0204249 0,02721058 ! autophagy GO:0006914 41 27 0,000 0,0204249 0,02719552 ! male gonad development GO:0008584 44 27 0,000 0,0204249 0,02718048 ! response to toxin GO:0009636 47 27 0,000 0,0204249 0,02716546 ! primary neural tube formation GO:0014020 51 27 0,000 0,0204249 0,02715045 ! base-excision repair GO:0006284 41 27 0,000 0,0204249 0,02713546 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0204249 0,02712048 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0204249 0,02710552 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0204249 0,02709058 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0204249 0,02707565 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0204249 0,02706074 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0204249 0,02704585 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,0204249 0,02703097 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02117366 0,0280065 ! circadian rhythm GO:0007623 50 28 0,000 0,02117366 0,02799112 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02117366 0,02797574 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02117366 0,02796039 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02117366 0,02794505 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02117366 0,02792973 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02117366 0,02791443 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02117366 0,02789914 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02117366 0,02788387 ! synaptogenesis GO:0007416 42 28 0,000 0,02117366 0,02786862 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02117366 0,02785338 ! lipid oxidation GO:0034440 43 28 0,000 0,02117366 0,02783816 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02117366 0,02782296 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,02117366 0,02780777 ! translational initiation GO:0006413 65 29 0,000 0,02192188 0,0287747 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,02192188 0,02875901 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02192188 0,02874334 ! regulation of pH GO:0006885 43 29 0,000 0,02192188 0,02872769 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02192188 0,02871205 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02192188 0,02869643 ! catechol metabolic process GO:0009712 54 29 0,000 0,02192188 0,02868082 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02192188 0,02866524 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02192188 0,02864967 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02192188 0,02863411 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02192188 0,02861857 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02192188 0,02860306 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02192188 0,02858755 ! cell fate determination GO:0001709 60 29 0,000 0,02192188 0,02857207 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02192188 0,0285566 ! detection of light stimulus GO:0009583 38 29 0,000 0,02192188 0,02854114 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,02192188 0,02852571 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,02192188 0,02851029 ! tissue homeostasis GO:0001894 48 29 0,000 0,02192188 0,02849489 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,02192188 0,0284795 ! phenol metabolic process GO:0018958 55 30 0,000 0,02266954 0,02943493 ! zinc ion transport GO:0006829 45 30 0,000 0,02266954 0,02941905 ! membrane docking GO:0022406 61 30 0,000 0,02266954 0,02940319 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02266954 0,02938735 ! cell junction assembly GO:0034329 78 30 0,000 0,02266954 0,02937152 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02266954 0,02935572 ! acute-phase response GO:0006953 49 30 0,000 0,02266954 0,02933992 ! myofibril assembly GO:0030239 47 30 0,000 0,02266954 0,02932415 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02266954 0,02930839 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02266954 0,02929265 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02266954 0,02927693 ! phospholipid transport GO:0015914 51 30 0,000 0,02266954 0,02926122 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02266954 0,02924553 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02266954 0,02922986 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02266954 0,0292142 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02266954 0,02919857 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02266954 0,02918294 ! eye morphogenesis GO:0048592 60 30 0,000 0,02266954 0,02916734 ! response to heat GO:0009408 50 30 0,000 0,02266954 0,02915175 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02341666 0,03009642 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02341666 0,03008035 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02341666 0,0300643 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02341666 0,03004826 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02341666 0,03003224 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,02341666 0,03001624 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02341666 0,03000026 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02341666 0,0299843 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02341666 0,02996835 ! ovulation cycle process GO:0022602 49 31 0,000 0,02341666 0,02995241 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02341666 0,0299365 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02341666 0,0299206 ! peptide transport GO:0015833 55 31 0,000 0,02341666 0,02990472 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02341666 0,02988885 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02341666 0,02987301 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02341666 0,02985718 ! natural killer cell activation GO:0030101 45 31 0,000 0,02341666 0,02984136 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02341666 0,02982556 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02341666 0,02980978 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02341666 0,02979402 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02341666 0,02977827 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02341666 0,02976254 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02416324 0,03069522 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02416324 0,03067902 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02416324 0,03066284 ! cholesterol transport GO:0030301 56 32 0,000 0,02416324 0,03064668 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02416324 0,03063053 ! spliceosome assembly GO:0000245 67 32 0,000 0,02416324 0,0306144 ! spindle organization GO:0007051 46 32 0,000 0,02416324 0,03059829 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02416324 0,03058219 ! metanephros development GO:0001656 74 32 0,000 0,02416324 0,03056611 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02416324 0,03055005 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02416324 0,03053401 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02416324 0,03051798 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02416324 0,03050197 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,02416324 0,03048597 ! muscle cell development GO:0055001 49 32 0,000 0,02416324 0,03046999 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02416324 0,03045403 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02416324 0,03043809 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02416324 0,03042216 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02416324 0,03040625 ! ovulation cycle GO:0042698 51 32 0,000 0,02416324 0,03039035 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02416324 0,03037448 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02416324 0,03035861 ! hindbrain development GO:0030902 61 32 0,000 0,02416324 0,03034277 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02416324 0,03032694 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02416324 0,03031113 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02416324 0,03029533 ! gene silencing GO:0016458 65 32 0,000 0,02416324 0,03027956 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,02490926 0,03119817 ! post-embryonic development GO:0009791 69 33 0,000 0,02490926 0,03118194 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,02490926 0,03116573 ! protein targeting to membrane GO:0006612 68 33 0,000 0,02490926 0,03114953 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,02490926 0,03113335 ! ceramide metabolic process GO:0006672 64 33 0,000 0,02490926 0,03111718 ! cell fate specification GO:0001708 52 33 0,000 0,02490926 0,03110103 ! sterol transport GO:0015918 57 33 0,000 0,02490926 0,0310849 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,02490926 0,03106879 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,02490926 0,03105269 ! adult locomotory behavior GO:0008344 59 33 0,000 0,02490926 0,03103661 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,02490926 0,03102054 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,02490926 0,0310045 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,02565475 0,03191588 ! glial cell differentiation GO:0010001 63 34 0,000 0,02565475 0,03189939 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,02565475 0,03188291 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,02565475 0,03186645 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,02565475 0,03185001 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,02565475 0,03183358 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,02565475 0,03181718 ! mismatch repair GO:0006298 46 34 0,000 0,02565475 0,03180078 ! spermatid development GO:0007286 63 34 0,000 0,02565475 0,03178441 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,02565475 0,03176805 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,02565475 0,03175171 ! placenta development GO:0001890 53 34 0,000 0,02565475 0,03173538 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,02565475 0,03171907 ! regulation of muscle development GO:0048634 70 35 0,000 0,02639968 0,03262334 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,02639968 0,03260659 ! negative regulation of secretion GO:0051048 63 35 0,000 0,02639968 0,03258986 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,02639968 0,03257315 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,02639968 0,03255645 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,02639968 0,03253977 ! odontogenesis GO:0042476 66 35 0,000 0,02639968 0,03252311 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,02639968 0,03250647 ! female gonad development GO:0008585 58 35 0,000 0,02639968 0,03248984 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,02639968 0,03247323 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,02639968 0,03245664 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,02639968 0,03244006 ! cytokine production GO:0001816 59 35 0,000 0,02639968 0,0324235 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,02639968 0,03240696 ! neural tube formation GO:0001841 67 35 0,000 0,02639968 0,03239043 ! vesicle localization GO:0051648 64 35 0,000 0,02639968 0,03237392 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,02714408 0,03326981 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,02714408 0,03325287 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,02714408 0,03323595 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,02714408 0,03321905 ! cell junction organization GO:0034330 86 36 0,000 0,02714408 0,03320216 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,02714408 0,03318529 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,02714408 0,03316843 ! positive regulation of cell development GO:0010720 80 36 0,000 0,02714408 0,0331516 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,02714408 0,03313478 ! regulation of proteolysis GO:0030162 72 36 0,000 0,02714408 0,03311797 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,02714408 0,03310119 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,02714408 0,03308442 ! aerobic respiration GO:0009060 55 36 0,000 0,02714408 0,03306767 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,02714408 0,03305093 ! embryonic organ development GO:0048568 57 36 0,000 0,02714408 0,03303422 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,02714408 0,03301752 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,02714408 0,03300083 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,02788792 0,03388805 ! meiosis I GO:0007127 65 37 0,000 0,02788792 0,03387095 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,02788792 0,03385386 ! sister chromatid segregation GO:0000819 58 37 0,000 0,02788792 0,03383678 ! actomyosin structure organization GO:0031032 62 37 0,000 0,02788792 0,03381973 ! organic anion transport GO:0015711 68 37 0,000 0,02788792 0,03380269 ! tissue remodeling GO:0048771 76 37 0,000 0,02788792 0,03378567 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,02788792 0,03376867 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,02788792 0,03375168 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,02788792 0,03373471 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,02788792 0,03371776 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,02788792 0,03370083 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,02788792 0,03368391 ! glycogen metabolic process GO:0005977 61 37 0,000 0,02788792 0,03366701 ! pigment metabolic process GO:0042440 80 37 0,000 0,02788792 0,03365012 ! spermatid differentiation GO:0048515 66 37 0,000 0,02788792 0,03363326 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,02788792 0,0336164 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,02863123 0,03449511 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,02863123 0,03447784 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,02863123 0,0344606 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,02863123 0,03444337 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,02863123 0,03442615 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,02863123 0,03440896 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,02863123 0,03439178 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,02863123 0,03437462 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,02863123 0,03435747 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,02863123 0,03434035 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,02863123 0,03432324 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,02863123 0,03430614 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,02863123 0,03428907 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,02863123 0,03427201 ! glucan metabolic process GO:0044042 62 38 0,000 0,02863123 0,03425496 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,02937399 0,03512615 ! mammary gland development GO:0030879 86 39 0,000 0,02937399 0,0351087 ! learning GO:0007612 77 39 0,000 0,02937399 0,03509127 ! ear morphogenesis GO:0042471 60 39 0,000 0,02937399 0,03507385 ! organic ether metabolic process GO:0018904 55 39 0,000 0,02937399 0,03505646 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,02937399 0,03503907 ! segmentation GO:0035282 67 39 0,000 0,02937399 0,03502171 ! ion transmembrane transport GO:0034220 66 39 0,000 0,02937399 0,03500437 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,02937399 0,03498704 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,02937399 0,03496972 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,02937399 0,03495243 ! RNA modification GO:0009451 57 39 0,000 0,02937399 0,03493515 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,02937399 0,03491789 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,0301162 0,03578251 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,0301162 0,03576485 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,0301162 0,03574721 ! feeding behavior GO:0007631 59 40 0,000 0,0301162 0,03572958 ! negative regulation of binding GO:0051100 72 40 0,000 0,0301162 0,03571197 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,0301162 0,03569438 ! mesenchymal cell development GO:0014031 87 40 0,000 0,0301162 0,0356768 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,0301162 0,03565925 ! maintenance of protein location GO:0045185 91 40 0,000 0,0301162 0,03564171 ! cytokinesis GO:0000910 72 40 0,000 0,0301162 0,03562418 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03085788 0,03648357 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03085788 0,03646565 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03085788 0,03644774 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03085788 0,03642986 ! gliogenesis GO:0042063 88 41 0,000 0,03085788 0,03641199 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03085788 0,03639414 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03085788 0,03637631 ! T cell differentiation GO:0030217 81 41 0,000 0,03085788 0,0363585 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03085788 0,0363407 ! female gamete generation GO:0007292 61 41 0,000 0,03085788 0,03632292 ! polyol metabolic process GO:0019751 66 41 0,000 0,03085788 0,03630516 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,03085788 0,03628742 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,03159901 0,0371408 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,03159901 0,03712266 ! regulation of tube size GO:0035150 71 42 0,000 0,03159901 0,03710455 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,03159901 0,03708645 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,03159901 0,03706837 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,03159901 0,0370503 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,03159901 0,03703225 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,03159901 0,03701422 ! neuron migration GO:0001764 79 42 0,000 0,03159901 0,03699621 ! regulation of protein secretion GO:0050708 71 42 0,000 0,03159901 0,03697822 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,03159901 0,03696024 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,0323396 0,0378081 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,0323396 0,03778974 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,0323396 0,0377714 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,0323396 0,03775307 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,0323396 0,03773476 ! glucose transport GO:0015758 65 43 0,000 0,0323396 0,03771647 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,0323396 0,0376982 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,0323396 0,03767994 ! neural tube development GO:0021915 77 43 0,000 0,0323396 0,0376617 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,0323396 0,03764348 ! striated muscle contraction GO:0006941 77 43 0,000 0,0323396 0,03762528 ! phagocytosis GO:0006909 90 43 0,000 0,0323396 0,03760709 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,0323396 0,03758893 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,03307965 0,03843053 ! hexose transport GO:0008645 67 44 0,000 0,03307965 0,03841198 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,03307965 0,03839345 ! male sex differentiation GO:0046661 76 44 0,000 0,03307965 0,03837494 ! double-strand break repair GO:0006302 81 44 0,000 0,03307965 0,03835645 ! biopolymer methylation GO:0043414 84 44 0,000 0,03307965 0,03833797 ! B cell differentiation GO:0030183 107 44 0,000 0,03307965 0,03831951 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,03307965 0,03830107 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,03307965 0,03828265 ! developmental growth GO:0048589 82 44 0,000 0,03307965 0,03826424 ! maintenance of location in cell GO:0051651 97 44 0,000 0,03307965 0,03824586 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,03381915 0,03908208 ! glycolysis GO:0006096 65 45 0,000 0,03381915 0,03906331 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,03381915 0,03904457 ! leukocyte migration GO:0050900 68 45 0,000 0,03381915 0,03902584 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,03381915 0,03900713 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,03381915 0,03898844 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,03381915 0,03896977 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,03381915 0,03895112 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,03381915 0,03893248 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,03381915 0,03891386 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,03381915 0,03889526 ! cell growth GO:0016049 84 45 0,000 0,03381915 0,03887668 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,03455812 0,03970718 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,03455812 0,03968822 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,03455812 0,03966929 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,03455812 0,03965037 ! pigmentation GO:0043473 100 46 0,000 0,03455812 0,03963147 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,03455812 0,03961259 ! positive regulation of defense response GO:0031349 76 47 0,000 0,03529654 0,04043975 ! endosome transport GO:0016197 108 47 0,000 0,03529654 0,0404205 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,03529654 0,04040128 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,03529654 0,04038206 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,03529654 0,04036287 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,03529654 0,0403437 ! JNK cascade GO:0007254 91 47 0,000 0,03529654 0,04032454 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,03529654 0,0403054 ! methylation GO:0032259 90 47 0,000 0,03529654 0,04028628 ! protein homooligomerization GO:0051260 76 47 0,000 0,03529654 0,04026718 ! mitochondrial transport GO:0006839 82 48 0,000 0,03603443 0,04108949 ! Notch signaling pathway GO:0007219 96 48 0,000 0,03603443 0,04107003 ! cellular component disassembly GO:0022411 86 48 0,000 0,03603443 0,04105058 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,03603443 0,04103115 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,03603443 0,04101175 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,03603443 0,04099235 ! activation of caspase activity GO:0006919 84 48 0,000 0,03603443 0,04097298 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,03603443 0,04095363 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,03603443 0,04093429 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,03603443 0,04091497 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,03677177 0,04173249 ! regulation of action potential GO:0001508 95 49 0,000 0,03677177 0,04171281 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,03677177 0,04169316 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,03677177 0,04167352 ! regulation of ion transport GO:0043269 77 49 0,000 0,03677177 0,0416539 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,03677177 0,0416343 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,03677177 0,04161471 ! endocrine system development GO:0035270 104 49 0,000 0,03677177 0,04159515 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,03677177 0,0415756 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,03677177 0,04155607 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,03677177 0,04153656 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,03677177 0,04151707 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,03750858 0,0423291 ! neuromuscular process GO:0050905 99 50 0,000 0,03750858 0,04230925 ! regulation of ossification GO:0030278 117 50 0,000 0,03750858 0,04228943 ! inner ear development GO:0048839 79 50 0,000 0,03750858 0,04226962 ! histone modification GO:0016570 91 50 0,000 0,03750858 0,04224983 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,03750858 0,04223006 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,03750858 0,04221031 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,03750858 0,04219057 ! positive regulation of binding GO:0051099 78 51 0,000 0,03824484 0,04299864 ! viral infectious cycle GO:0019058 99 51 0,000 0,03824484 0,04297856 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,03824484 0,04295849 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,03824484 0,04293845 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,03824484 0,04291842 ! excretion GO:0007588 83 51 0,000 0,03824484 0,04289841 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,03824484 0,04287842 ! chromatin remodeling GO:0006338 109 51 0,000 0,03824484 0,04285845 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,03824484 0,0428385 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,03824484 0,04281856 ! vesicle organization GO:0016050 107 51 0,000 0,03824484 0,04279865 ! regulation of cell shape GO:0008360 125 51 0,000 0,03824484 0,04277875 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,03824484 0,04275887 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,03898057 0,04356119 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,03898057 0,04354097 ! membrane fusion GO:0006944 110 52 0,000 0,03898057 0,04352076 ! covalent chromatin modification GO:0016569 101 52 0,000 0,03898057 0,04350058 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,03898057 0,04348041 ! amino acid activation GO:0043038 92 52 0,000 0,03898057 0,04346026 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,03898057 0,04344013 ! synapse organization GO:0050808 85 52 0,000 0,03898057 0,04342002 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,03971576 0,04421847 ! RNA catabolic process GO:0006401 93 53 0,000 0,03971576 0,04419802 ! regulation of translational initiation GO:0006446 82 53 0,000 0,03971576 0,04417758 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,03971576 0,04415717 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,03971576 0,04413677 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,03971576 0,0441164 ! cell maturation GO:0048469 100 53 0,000 0,03971576 0,04409604 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,03971576 0,0440757 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,03971576 0,04405538 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,04045041 0,04484962 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,04045041 0,04482896 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,04045041 0,04480832 ! cell recognition GO:0008037 85 54 0,000 0,04045041 0,0447877 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,04045041 0,0447671 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,04045041 0,04474652 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,04045041 0,04472596 ! chloride transport GO:0006821 90 55 0,000 0,04118452 0,04551675 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,04118452 0,04549585 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,04118452 0,04547497 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,04118452 0,04545411 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,04118452 0,04543327 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,04118452 0,04541245 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,04118452 0,04539164 ! aging GO:0007568 103 55 0,000 0,04118452 0,04537086 ! heart morphogenesis GO:0003007 97 55 0,000 0,04118452 0,04535009 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,04118452 0,04532935 ! RNA elongation GO:0006354 79 55 0,000 0,04118452 0,04530862 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,04118452 0,04528791 ! regulation of actin filament length GO:0030832 105 56 0,000 0,0419181 0,04607352 ! sensory perception of smell GO:0007608 80 56 0,000 0,0419181 0,04605248 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,0419181 0,04603147 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,0419181 0,04601047 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,0419181 0,04598949 ! regulation of DNA replication GO:0006275 101 56 0,000 0,0419181 0,04596852 ! proton transport GO:0015992 94 56 0,000 0,0419181 0,04594758 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,0419181 0,04592666 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,04265114 0,04670853 ! muscle fiber development GO:0048747 112 57 0,000 0,04265114 0,04668728 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,04265114 0,04666604 ! lipid modification GO:0030258 97 57 0,000 0,04265114 0,04664483 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,04265114 0,04662364 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,04265114 0,04660247 ! maintenance of location GO:0051235 118 57 0,000 0,04265114 0,04658131 ! hydrogen transport GO:0006818 97 58 0,000 0,04338364 0,04735982 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,04338364 0,04733834 ! regulation of endocytosis GO:0030100 91 58 0,000 0,04338364 0,04731688 ! adult behavior GO:0030534 99 58 0,000 0,04338364 0,04729544 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,04338364 0,04727402 ! positive regulation of secretion GO:0051047 95 59 0,000 0,0441156 0,04804986 ! regulation of cellular component size GO:0032535 109 59 0,000 0,0441156 0,04802812 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,0441156 0,0480064 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,0441156 0,04798469 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,0441156 0,04796301 ! DNA catabolic process GO:0006308 86 59 0,000 0,0441156 0,04794135 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,0441156 0,0479197 ! establishment of organelle localization GO:0051656 109 59 0,000 0,0441156 0,04789808 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,04484704 0,04867026 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,04484704 0,04864832 ! regulation of heart contraction GO:0008016 110 60 0,000 0,04484704 0,04862639 ! camera-type eye development GO:0043010 116 60 0,000 0,04484704 0,04860449 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,04484704 0,04858261 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,04484704 0,04856074 ! kidney development GO:0001822 122 60 0,000 0,04484704 0,0485389 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,04557793 0,04930778 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,04557793 0,04928562 ! tRNA processing GO:0008033 89 61 0,000 0,04557793 0,04926348 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,04557793 0,04924136 ! ear development GO:0043583 103 62 0,000 0,04630829 0,05000797 ! viral reproductive process GO:0022415 126 62 0,000 0,04630829 0,04998553 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,04630829 0,04996312 ! gonad development GO:0008406 98 62 0,000 0,04630829 0,04994072 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,04630829 0,04991835 ! regulation of mitosis GO:0007088 105 63 0,000 0,04703812 0,05068236 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,04703812 0,05065967 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,04703812 0,05063701 ! detection of external stimulus GO:0009581 91 63 0,000 0,04703812 0,05061436 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,04703812 0,05059173 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,04703812 0,05056913 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,04776741 0,05133023 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,04776741 0,05130731 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,04776741 0,05128442 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,04776741 0,05126154 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,04849617 0,05202041 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,04849617 0,05199723 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,04849617 0,05197406 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,04849617 0,05195092 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,04849617 0,0519278 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,04922439 0,05268411 ! actin filament organization GO:0007015 148 66 0,000 0,04922439 0,05266068 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,04922439 0,05263728 ! extracellular matrix organization GO:0030198 133 66 0,000 0,04922439 0,0526139 ! secondary metabolic process GO:0019748 116 66 0,000 0,04922439 0,05259053 ! developmental maturation GO:0021700 116 66 0,000 0,04922439 0,05256719 ! cell projection assembly GO:0030031 120 66 0,000 0,04922439 0,05254387 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,04995208 0,05329699 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,04995208 0,05327336 ! activation of MAPK activity GO:0000187 115 67 0,000 0,04995208 0,05324976 ! lung development GO:0030324 144 67 0,000 0,04995208 0,05322618 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,04995208 0,05320261 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,04995208 0,05317907 ! hexose catabolic process GO:0019320 104 67 0,000 0,04995208 0,05315555 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,04995208 0,05313205 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,04995208 0,05310857 ! adaptive immune response GO:0002250 119 67 0,000 0,04995208 0,05308512 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,04995208 0,05306168 ! amino acid transport GO:0006865 125 68 0,000 0,05067924 0,05381035 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,05067924 0,05378661 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,05067924 0,0537629 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,05067924 0,0537392 ! viral reproduction GO:0016032 134 68 0,000 0,05067924 0,05371553 ! regulation of lipase activity GO:0060191 130 68 0,000 0,05067924 0,05369187 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,05067924 0,05366824 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,05140586 0,05441377 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,05140586 0,05438985 ! urogenital system development GO:0001655 137 69 0,000 0,05140586 0,05436594 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,05140586 0,05434205 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,05140586 0,05431819 ! antigen processing and presentation GO:0019882 104 69 0,000 0,05140586 0,05429434 ! appendage morphogenesis GO:0035107 135 70 0,000 0,05213196 0,05503707 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,05213196 0,05501293 ! amine catabolic process GO:0009310 117 71 0,000 0,05285752 0,05575414 ! reproductive structure development GO:0048608 113 71 0,000 0,05285752 0,05572971 ! appendage development GO:0048736 136 71 0,000 0,05285752 0,0557053 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,05285752 0,05568091 ! B cell activation GO:0042113 160 71 0,000 0,05285752 0,05565654 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,05285752 0,05563219 ! regulation of immune effector process GO:0002697 137 71 0,000 0,05285752 0,05560787 ! acute inflammatory response GO:0002526 113 72 0,000 0,05358255 0,05634599 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,05358255 0,05632137 ! carbohydrate transport GO:0008643 110 72 0,000 0,05358255 0,05629678 ! respiratory system development GO:0060541 153 72 0,000 0,05358255 0,0562722 ! learning or memory GO:0007611 147 73 0,000 0,05430705 0,05700819 ! regulation of blood pressure GO:0008217 125 73 0,000 0,05430705 0,05698332 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,05430705 0,05695848 ! axon guidance GO:0007411 139 73 0,000 0,05430705 0,05693367 ! fertilization GO:0009566 90 73 0,000 0,05430705 0,05690887 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,05503102 0,05764242 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,05503102 0,05761733 ! neurotransmitter transport GO:0006836 123 74 0,000 0,05503102 0,05759227 ! meiosis GO:0007126 121 74 0,000 0,05503102 0,05756723 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,05503102 0,05754221 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,05503102 0,05751722 ! eye development GO:0001654 143 74 0,000 0,05503102 0,05749224 ! organelle localization GO:0051640 136 74 0,000 0,05503102 0,05746729 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,05575446 0,0581975 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,05575446 0,05817226 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,05575446 0,05814704 ! meiotic cell cycle GO:0051321 122 75 0,000 0,05575446 0,05812185 ! rhythmic process GO:0048511 128 75 0,000 0,05575446 0,05809668 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,05575446 0,05807153 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,05647737 0,05879903 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,05647737 0,05877359 ! defense response to bacterium GO:0042742 89 76 0,000 0,05647737 0,05874818 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,05647737 0,0587228 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,05647737 0,05869743 ! regulation of catabolic process GO:0009894 161 76 0,000 0,05647737 0,05867209 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,05719975 0,05939689 ! blood coagulation GO:0007596 146 78 0,000 0,0579216 0,06012052 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,0579216 0,0600946 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,0579216 0,06006869 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,0579216 0,06004281 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,05864292 0,06076437 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,05864292 0,06073821 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,05864292 0,06071208 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,05864292 0,06068597 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,05936372 0,06140546 ! muscle cell differentiation GO:0042692 159 80 0,000 0,05936372 0,06137907 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,05936372 0,06135271 ! protein import into nucleus GO:0006606 158 80 0,000 0,05936372 0,06132636 ! inorganic anion transport GO:0015698 138 80 0,000 0,05936372 0,06130004 ! T cell activation GO:0042110 168 81 0,000 0,06008398 0,06201719 ! response to hypoxia GO:0001666 171 81 0,000 0,06008398 0,06199059 ! digestion GO:0007586 112 81 0,000 0,06008398 0,06196402 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,06008398 0,06193747 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,06008398 0,06191095 ! nuclear import GO:0051170 161 81 0,000 0,06008398 0,06188444 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,06008398 0,06185796 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,06080372 0,06257218 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,06080372 0,06254543 ! response to drug GO:0042493 143 82 0,000 0,06080372 0,0625187 ! response to nutrient GO:0007584 125 82 0,000 0,06080372 0,06249199 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,06080372 0,06246531 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,06080372 0,06243865 ! response to oxygen levels GO:0070482 176 83 0,000 0,06152293 0,06315025 ! regulation of lyase activity GO:0051339 160 83 0,000 0,06152293 0,06312332 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,06224162 0,06383347 ! hemostasis GO:0007599 158 84 0,000 0,06224162 0,06380628 ! negative regulation of transport GO:0051051 153 84 0,000 0,06224162 0,0637791 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,06224162 0,06375195 ! nucleosome assembly GO:0006334 122 85 0,000 0,06295978 0,06446009 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,06295978 0,06443268 ! amine biosynthetic process GO:0009309 138 86 0,000 0,06367741 0,06513939 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,06367741 0,06511171 ! chromatin assembly GO:0031497 124 86 0,000 0,06367741 0,06508405 ! tube morphogenesis GO:0035239 176 86 0,000 0,06367741 0,06505641 ! alcohol catabolic process GO:0046164 130 86 0,000 0,06367741 0,0650288 ! amine transport GO:0015837 155 86 0,000 0,06367741 0,06500121 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,06439451 0,06570534 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,06439451 0,06567749 ! protein localization in nucleus GO:0034504 176 87 0,000 0,06439451 0,06564966 ! regulation of protein transport GO:0051223 154 87 0,000 0,06439451 0,06562186 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,06511109 0,066324 ! regulation of DNA binding GO:0051101 155 88 0,000 0,06511109 0,06629593 ! gland development GO:0048732 206 88 0,000 0,06511109 0,06626789 ! regulation of neurological system process GO:0031644 148 88 0,000 0,06511109 0,06623987 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,06511109 0,06621187 ! cellular defense response GO:0006968 114 89 0,000 0,06582715 0,06691176 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,06582715 0,0668835 ! ossification GO:0001503 188 90 0,000 0,06654268 0,06758197 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,06654268 0,06755346 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,06654268 0,06752497 ! sex differentiation GO:0007548 145 90 0,000 0,06654268 0,0674965 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,06654268 0,06746805 ! bone development GO:0060348 189 91 0,000 0,06725769 0,06816428 ! sterol metabolic process GO:0016125 152 91 0,000 0,06725769 0,06813558 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,06725769 0,0681069 ! regulation of defense response GO:0031347 149 92 0,000 0,06797217 0,06880145 ! nucleosome organization GO:0034728 138 92 0,000 0,06797217 0,06877252 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,06797217 0,06874361 ! vitamin metabolic process GO:0006766 139 92 0,000 0,06797217 0,06871473 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,06868613 0,06940732 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,06868613 0,06937818 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,06868613 0,06934907 ! regulation of membrane potential GO:0042391 164 93 0,000 0,06868613 0,06931998 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,06868613 0,06929092 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,06939957 0,06998129 ! female pregnancy GO:0007565 164 94 0,000 0,06939957 0,06995197 ! transcription initiation GO:0006352 153 94 0,000 0,06939957 0,06992268 ! regulation of T cell activation GO:0050863 158 94 0,000 0,06939957 0,06989341 ! forebrain development GO:0030900 188 95 0,000 0,07011248 0,07058185 ! leukocyte differentiation GO:0002521 202 96 0,000 0,07082487 0,0712692 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,07082487 0,0712394 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,07082487 0,07120963 ! positive regulation of immune response GO:0050778 156 96 0,000 0,07082487 0,07117989 ! detection of stimulus GO:0051606 151 96 0,000 0,07082487 0,07115017 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,07153674 0,07183531 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,07153674 0,07180534 ! protein ubiquitination GO:0016567 217 97 0,000 0,07153674 0,0717754 ! hormone metabolic process GO:0042445 157 97 0,000 0,07153674 0,07174548 ! regulation of protein localization GO:0032880 176 97 0,000 0,07153674 0,07171558 ! response to virus GO:0009615 160 98 0,000 0,07224809 0,07239854 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,07224809 0,0723684 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,07224809 0,07233829 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,07295892 0,07301961 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,07295892 0,07298925 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,07295892 0,07295892 GO:0060538|skeletal muscle organ development,