pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/3925-4-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of focal adhesion formation GO:0051893 7 6 1,000 9,493E-06 0,01749647 ! regulation of Rho GTPase activity GO:0032319 6 6 1,000 9,493E-06 8,748E-03 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 9,493E-06 5,832E-03 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 1,329E-05 6,121E-03 ! cellular protein complex disassembly GO:0043624 8 7 1,000 1,329E-05 4,897E-03 GO:0043241|protein complex disassembly, ! regulation of stress fiber formation GO:0051492 9 8 1,000 1,771E-05 5,439E-03 ! negative regulation of signal transduction GO:0009968 71 71 2,000 2,06E-05 5,425E-03 ! regulation of dephosphorylation GO:0035303 9 9 1,000 2,276E-05 5,243E-03 ! regulation of actin filament bundle formation GO:0032231 10 9 1,000 2,276E-05 4,66E-03 ! negative regulation of cell communication GO:0010648 76 76 2,000 2,53E-05 4,663E-03 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 2,844E-05 4,764E-03 ! cellular macromolecular complex disassembly GO:0034623 12 11 1,000 3,474E-05 5,336E-03 ! mitotic spindle organization GO:0007052 11 11 1,000 3,474E-05 4,925E-03 ! negative regulation of translation GO:0017148 12 12 1,000 4,167E-05 5,486E-03 ! negative regulation of protein modification process GO:0031400 13 13 1,000 4,923E-05 6,049E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 4,923E-05 5,671E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 4,923E-05 5,337E-03 GO:0001952|regulation of cell-matrix adhesion, ! macromolecular complex disassembly GO:0032984 15 14 1,000 5,742E-05 5,879E-03 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 8,571E-05 8,314E-03 ! RNA export from nucleus GO:0006405 22 22 1,000 1,453E-04 0,01338889 ! spindle organization GO:0007051 22 22 1,000 1,453E-04 0,01275133 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 1,453E-04 0,01217172 ! cellular component disassembly GO:0022411 26 25 1,000 1,885E-04 0,01510255 ! response to insulin stimulus GO:0032868 28 26 1,000 2,041E-04 0,01567329 ! nuclear export GO:0051168 32 32 1,000 3,108E-04 0,02290961 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 3,512E-04 0,02489591 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 4,165E-04 0,02842777 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 5,12E-04 0,03369869 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 5,374E-04 0,03415022 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 5,9E-04 0,03624271 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 6,172E-04 0,03669065 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 6,172E-04 0,03554407 ! regulation of actin filament-based process GO:0032970 47 46 1,000 6,45E-04 0,03601965 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 6,45E-04 0,03496025 ! positive regulation of ligase activity GO:0051351 47 46 1,000 6,45E-04 0,03396138 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 7,024E-04 0,03595687 ! regulation of ligase activity GO:0051340 50 49 1,000 7,32E-04 0,03645961 ! RNA transport GO:0050658 50 50 1,000 7,622E-04 0,03696494 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! RNA localization GO:0006403 52 52 1,000 8,244E-04 0,03895638 ! regulation of GTPase activity GO:0043087 53 52 1,000 8,244E-04 0,03798247 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 8,564E-04 0,03849428 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 9,221E-04 0,04046412 ! regulation of cell adhesion GO:0030155 56 55 1,000 9,221E-04 0,03952309 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 1,097E-03 0,04594822 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 1,134E-03 0,04643203 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 1,171E-03 0,04691846 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 1,247E-03 0,04891755 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 1,287E-03 0,04939978 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 1,326E-03 0,04988444 ! regulation of translation GO:0006417 69 69 1,000 1,449E-03 0,05340534 ! ribosome biogenesis GO:0042254 71 71 1,000 1,534E-03 0,05541721 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 1,577E-03 0,05588263 ! regulation of protein modification process GO:0031399 79 78 1,000 1,848E-03 0,06426639 ! nuclear transport GO:0051169 79 79 1,000 1,895E-03 0,06468941 GO:0006913|nucleocytoplasmic transport, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 2,453E-03 0,08220787 ! negative regulation of cell cycle GO:0045786 92 91 1,000 2,507E-03 0,08252207 ! DNA replication GO:0006260 91 91 1,000 2,507E-03 0,08107431 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 2,902E-03 0,09222711 ! anti-apoptosis GO:0006916 100 99 1,000 2,961E-03 0,09249722 ! response to hormone stimulus GO:0009725 102 100 1,000 3,02E-03 0,09277564 ! rRNA transcription GO:0009303 5 5 0,000 4,354E-03 0,13155183 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 4,354E-03 0,12943003 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 4,354E-03 0,12737558 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 4,354E-03 0,12538534 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 4,354E-03 0,12345633 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 4,354E-03 0,12158578 ! reproductive cellular process GO:0048610 5 5 0,000 4,354E-03 0,11977107 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 4,354E-03 0,11800973 ! negative regulation of blood pressure GO:0045776 6 5 0,000 4,354E-03 0,11629944 ! prostate gland development GO:0030850 5 5 0,000 4,354E-03 0,11463802 ! metencephalon development GO:0022037 5 5 0,000 4,354E-03 0,1130234 ! water transport GO:0006833 5 5 0,000 4,354E-03 0,11145363 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 4,354E-03 0,10992687 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 4,354E-03 0,10844137 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 4,354E-03 0,10699549 ! glycerol metabolic process GO:0006071 5 5 0,000 4,354E-03 0,10558765 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 4,354E-03 0,10421638 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 4,354E-03 0,10288028 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 4,354E-03 0,10157799 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 4,354E-03 0,10030827 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 4,354E-03 0,0990699 ! filopodium assembly GO:0046847 7 5 0,000 4,354E-03 0,09786173 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 4,354E-03 0,09668267 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 4,354E-03 0,09553169 ! GTP metabolic process GO:0046039 5 5 0,000 4,354E-03 0,09440778 ! establishment of tissue polarity GO:0007164 5 5 0,000 4,354E-03 0,09331002 ! mRNA stabilization GO:0048255 5 5 0,000 4,354E-03 0,09223749 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 4,354E-03 0,09118934 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 4,354E-03 0,09016474 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 4,354E-03 0,08916291 ! social behavior GO:0035176 5 5 0,000 4,354E-03 0,08818309 ! macrophage chemotaxis GO:0048246 6 5 0,000 4,354E-03 0,08722458 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 4,354E-03 0,08628668 ! memory GO:0007613 5 5 0,000 4,354E-03 0,08536874 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 4,354E-03 0,08447012 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 4,354E-03 0,08359022 ! membrane hyperpolarization GO:0060081 5 5 0,000 4,354E-03 0,08272847 ! response to lipid GO:0033993 5 5 0,000 4,354E-03 0,0818843 ! erythrocyte maturation GO:0043249 5 5 0,000 4,354E-03 0,08105719 ! hippocampus development GO:0021766 6 5 0,000 4,354E-03 0,08024662 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 4,354E-03 0,07945209 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 4,354E-03 0,07867315 ! middle ear morphogenesis GO:0042474 5 5 0,000 4,354E-03 0,07790934 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 4,354E-03 0,07716021 ! mechanosensory behavior GO:0007638 5 5 0,000 4,354E-03 0,07642535 ! heart looping GO:0001947 5 5 0,000 4,354E-03 0,07570435 ! negative regulation of endocytosis GO:0045806 5 5 0,000 4,354E-03 0,07499684 ! response to interferon-gamma GO:0034341 5 5 0,000 4,354E-03 0,07430242 ! pseudouridine synthesis GO:0001522 5 5 0,000 4,354E-03 0,07362075 ! endocrine pancreas development GO:0031018 5 5 0,000 4,354E-03 0,07295147 ! pH reduction GO:0045851 5 5 0,000 4,354E-03 0,07229425 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 4,354E-03 0,07164876 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 4,354E-03 0,0710147 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 4,354E-03 0,07039177 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 4,354E-03 0,06977967 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 4,354E-03 0,06917812 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 4,354E-03 0,06858685 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 4,354E-03 0,06800561 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 4,354E-03 0,06743413 ! adrenal gland development GO:0030325 5 5 0,000 4,354E-03 0,06687218 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 4,354E-03 0,06631952 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 4,354E-03 0,06577591 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 4,354E-03 0,06524115 ! astrocyte differentiation GO:0048708 5 5 0,000 4,354E-03 0,06471501 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 4,354E-03 0,06419729 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 4,354E-03 0,06368779 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 4,354E-03 0,06318631 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 4,354E-03 0,06269267 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 4,354E-03 0,06220668 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 4,354E-03 0,06172817 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 4,354E-03 0,06125696 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 4,354E-03 0,06079289 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 4,354E-03 0,0603358 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 4,354E-03 0,05988553 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 4,354E-03 0,05944194 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 4,354E-03 0,05900486 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 4,354E-03 0,05857417 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 4,354E-03 0,05814972 ! response to ATP GO:0033198 5 5 0,000 4,354E-03 0,05773138 ! regulation of type I interferon production GO:0032479 5 5 0,000 4,354E-03 0,05731901 ! regulation of appetite GO:0032098 5 5 0,000 4,354E-03 0,05691249 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 4,354E-03 0,0565117 ! paraxial mesoderm development GO:0048339 5 5 0,000 4,354E-03 0,05611651 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 4,354E-03 0,05572682 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 4,354E-03 0,05534249 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 4,354E-03 0,05496344 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 4,354E-03 0,05458953 ! receptor clustering GO:0043113 5 5 0,000 4,354E-03 0,05422069 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 4,354E-03 0,05385679 ! fear response GO:0042596 5 5 0,000 4,354E-03 0,05349774 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 4,354E-03 0,05314345 ! lens development in camera-type eye GO:0002088 5 5 0,000 4,354E-03 0,05279383 ! retinol metabolic process GO:0042572 5 5 0,000 4,354E-03 0,05244877 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 4,354E-03 0,05210819 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 4,354E-03 0,05177201 ! positive regulation of exocytosis GO:0045921 6 5 0,000 4,354E-03 0,05144014 ! parturition GO:0007567 5 5 0,000 4,354E-03 0,05111249 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,354E-03 0,050789 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 4,354E-03 0,05046957 ! Schwann cell differentiation GO:0014037 5 5 0,000 4,354E-03 0,05015413 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 4,354E-03 0,04984262 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 4,354E-03 0,04953495 ! protein heterooligomerization GO:0051291 5 5 0,000 4,354E-03 0,04923105 ! regulation of gliogenesis GO:0014013 5 5 0,000 4,354E-03 0,04893086 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 4,354E-03 0,04863431 ! response to UV-B GO:0010224 5 5 0,000 4,354E-03 0,04834133 ! oligodendrocyte development GO:0014003 5 5 0,000 4,354E-03 0,04805187 ! hyaluronan metabolic process GO:0030212 5 5 0,000 4,354E-03 0,04776584 ! activated T cell proliferation GO:0050798 5 5 0,000 4,354E-03 0,0474832 ! interaction with symbiont GO:0051702 5 5 0,000 4,354E-03 0,04720389 ! cellular extravasation GO:0045123 5 5 0,000 4,354E-03 0,04692785 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 4,354E-03 0,04665501 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 4,354E-03 0,04638533 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 4,354E-03 0,04611874 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 4,354E-03 0,04585521 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 4,354E-03 0,04559467 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 4,354E-03 0,04533707 ! response to amine stimulus GO:0014075 5 5 0,000 4,354E-03 0,04508237 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 4,354E-03 0,04483051 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 4,354E-03 0,04458145 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 4,354E-03 0,04433515 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 4,354E-03 0,04409155 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 4,354E-03 0,04385061 ! neuron recognition GO:0008038 5 5 0,000 4,354E-03 0,04361229 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 4,354E-03 0,04337655 ! decidualization GO:0046697 5 5 0,000 4,354E-03 0,04314334 ! hair follicle maturation GO:0048820 5 5 0,000 4,354E-03 0,04291263 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 4,354E-03 0,04268437 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 4,354E-03 0,04245853 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 4,354E-03 0,04223506 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 4,354E-03 0,04201393 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 4,354E-03 0,04179511 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 4,354E-03 0,04157856 ! postreplication repair GO:0006301 5 5 0,000 4,354E-03 0,04136423 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 4,354E-03 0,04115211 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 4,354E-03 0,04094215 ! histone methylation GO:0016571 5 5 0,000 4,354E-03 0,04073432 ! DNA methylation GO:0006306 5 5 0,000 4,354E-03 0,04052859 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 4,354E-03 0,04032493 ! T cell lineage commitment GO:0002360 5 5 0,000 4,354E-03 0,04012331 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 4,354E-03 0,03992369 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 4,354E-03 0,03972605 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 4,354E-03 0,03953035 ! intracellular cholesterol transport GO:0032367 5 5 0,000 4,354E-03 0,03933658 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 4,354E-03 0,03914469 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 4,354E-03 0,03895467 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 4,354E-03 0,03876648 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 4,354E-03 0,0385801 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 4,354E-03 0,03839551 ! sterol catabolic process GO:0016127 5 5 0,000 4,354E-03 0,03821267 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 4,354E-03 0,03803157 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 4,354E-03 0,03785218 ! detection of biotic stimulus GO:0009595 5 5 0,000 4,354E-03 0,03767447 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 4,354E-03 0,03749842 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 4,354E-03 0,03732401 ! zymogen activation GO:0031638 5 5 0,000 4,354E-03 0,03715121 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 4,354E-03 0,03698001 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 4,354E-03 0,03681037 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 4,354E-03 0,03664229 ! peptidyl-lysine modification GO:0018205 5 5 0,000 4,354E-03 0,03647573 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 4,354E-03 0,03631069 ! peptidyl-histidine modification GO:0018202 5 5 0,000 4,354E-03 0,03614712 ! nucleosome positioning GO:0016584 5 5 0,000 4,354E-03 0,03598503 ! regulation of isotype switching GO:0045191 5 5 0,000 4,354E-03 0,03582438 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 4,354E-03 0,03566516 ! negative regulation of neurological system process GO:0031645 5 5 0,000 4,354E-03 0,03550735 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 4,354E-03 0,03535093 ! glutathione biosynthetic process GO:0006750 5 5 0,000 4,354E-03 0,03519588 ! NADPH regeneration GO:0006740 5 5 0,000 4,354E-03 0,03504219 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 4,354E-03 0,03488983 ! positive regulation of epidermis development GO:0045684 5 5 0,000 4,354E-03 0,03473879 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 4,354E-03 0,03458906 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 4,354E-03 0,03444061 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 4,354E-03 0,03429343 ! sarcomere organization GO:0045214 5 5 0,000 4,354E-03 0,0341475 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 4,354E-03 0,0340028 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 4,354E-03 0,03385933 ! negative regulation of glucose transport GO:0010829 5 5 0,000 4,354E-03 0,03371707 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 4,354E-03 0,03357599 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 4,354E-03 0,03343609 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 4,354E-03 0,03329735 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 4,354E-03 0,03315976 ! spleen development GO:0048536 5 5 0,000 4,354E-03 0,0330233 ! male genitalia development GO:0030539 5 5 0,000 4,354E-03 0,03288796 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 4,354E-03 0,03275372 ! quaternary ammonium group transport GO:0015697 5 5 0,000 4,354E-03 0,03262058 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 4,354E-03 0,03248851 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 4,354E-03 0,03235751 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 4,354E-03 0,03222756 ! removal of superoxide radicals GO:0019430 6 5 0,000 4,354E-03 0,03209865 ! myeloid cell homeostasis GO:0002262 5 5 0,000 4,354E-03 0,03197076 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 4,354E-03 0,0318439 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 4,354E-03 0,03171803 ! ATP catabolic process GO:0006200 5 5 0,000 4,354E-03 0,03159316 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 4,354E-03 0,03146926 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 4,354E-03 0,03134633 ! blastocyst formation GO:0001825 5 5 0,000 4,354E-03 0,03122436 ! regulation of fibrinolysis GO:0051917 5 5 0,000 4,354E-03 0,03110334 ! embryonic gut development GO:0048566 5 5 0,000 4,354E-03 0,03098325 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 4,354E-03 0,03086408 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 4,354E-03 0,03074583 ! activation of innate immune response GO:0002218 5 5 0,000 4,354E-03 0,03062848 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 4,354E-03 0,03051202 ! catecholamine transport GO:0051937 5 5 0,000 4,354E-03 0,03039645 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 4,354E-03 0,03028174 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 4,354E-03 0,0301679 ! muscle adaptation GO:0043500 5 5 0,000 4,354E-03 0,03005491 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 4,354E-03 0,02994277 ! embryonic heart tube development GO:0035050 5 5 0,000 4,354E-03 0,02983146 ! cardiac cell differentiation GO:0035051 6 5 0,000 4,354E-03 0,02972097 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 4,354E-03 0,0296113 ! defense response to fungus GO:0050832 5 5 0,000 4,354E-03 0,02950243 ! lysogeny GO:0030069 5 5 0,000 4,354E-03 0,02939436 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 4,354E-03 0,02928709 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 4,354E-03 0,02918059 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 4,354E-03 0,02907486 ! response to nicotine GO:0035094 5 5 0,000 4,354E-03 0,0289699 ! establishment of cell polarity GO:0030010 5 5 0,000 4,354E-03 0,02886569 ! mitochondrion localization GO:0051646 5 5 0,000 4,354E-03 0,02876223 ! nucleus localization GO:0051647 5 5 0,000 4,354E-03 0,02865951 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 4,354E-03 0,02855751 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 5,223E-03 0,03413509 ! axon extension GO:0048675 7 6 0,000 5,223E-03 0,03401447 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 5,223E-03 0,0338947 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 5,223E-03 0,03377577 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 5,223E-03 0,03365767 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 5,223E-03 0,0335404 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 5,223E-03 0,03342394 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 5,223E-03 0,03330829 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 5,223E-03 0,03319343 ! virus-host interaction GO:0019048 6 6 0,000 5,223E-03 0,03307936 ! regulation of S phase GO:0033261 6 6 0,000 5,223E-03 0,03296608 ! myotube differentiation GO:0014902 6 6 0,000 5,223E-03 0,03285357 ! regulation of B cell proliferation GO:0030888 6 6 0,000 5,223E-03 0,03274182 ! bone remodeling GO:0046849 6 6 0,000 5,223E-03 0,03263083 ! N-glycan processing GO:0006491 6 6 0,000 5,223E-03 0,03252059 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 5,223E-03 0,03241109 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 5,223E-03 0,03230233 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 5,223E-03 0,0321943 ! retina development in camera-type eye GO:0060041 6 6 0,000 5,223E-03 0,03208698 ! RNA methylation GO:0001510 6 6 0,000 5,223E-03 0,03198038 ! cartilage condensation GO:0001502 7 6 0,000 5,223E-03 0,03187449 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 5,223E-03 0,03176929 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 5,223E-03 0,03166478 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 5,223E-03 0,03156097 ! artery development GO:0060840 6 6 0,000 5,223E-03 0,03145783 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 5,223E-03 0,03135536 ! bile acid metabolic process GO:0008206 6 6 0,000 5,223E-03 0,03125355 ! androgen metabolic process GO:0008209 6 6 0,000 5,223E-03 0,03115241 ! estrogen metabolic process GO:0008210 6 6 0,000 5,223E-03 0,03105192 ! limbic system development GO:0021761 7 6 0,000 5,223E-03 0,03095207 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 5,223E-03 0,03085287 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 5,223E-03 0,0307543 ! positive regulation of heart contraction GO:0045823 6 6 0,000 5,223E-03 0,03065635 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 5,223E-03 0,03055903 ! pathogenesis GO:0009405 6 6 0,000 5,223E-03 0,03046232 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 5,223E-03 0,03036623 ! positive regulation of cell growth GO:0030307 6 6 0,000 5,223E-03 0,03027074 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 5,223E-03 0,03017585 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 5,223E-03 0,03008155 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 5,223E-03 0,02998783 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 5,223E-03 0,0298947 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 5,223E-03 0,02980215 ! arginine metabolic process GO:0006525 6 6 0,000 5,223E-03 0,02971017 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 5,223E-03 0,02961875 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 5,223E-03 0,0295279 ! glutamate catabolic process GO:0006538 7 6 0,000 5,223E-03 0,0294376 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 5,223E-03 0,02934785 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 5,223E-03 0,02925865 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 5,223E-03 0,02916998 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 5,223E-03 0,02908186 ! ER overload response GO:0006983 6 6 0,000 5,223E-03 0,02899426 ! V(D)J recombination GO:0033151 6 6 0,000 5,223E-03 0,02890719 ! focal adhesion formation GO:0048041 7 6 0,000 5,223E-03 0,02882064 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 5,223E-03 0,02873461 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 5,223E-03 0,02864909 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 5,223E-03 0,02856408 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 5,223E-03 0,02847957 ! regulation of heart rate GO:0002027 6 6 0,000 5,223E-03 0,02839556 ! lipid digestion GO:0044241 6 6 0,000 5,223E-03 0,02831204 ! asymmetric protein localization GO:0008105 6 6 0,000 5,223E-03 0,02822902 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 5,223E-03 0,02814648 ! phagocytosis, engulfment GO:0006911 6 6 0,000 5,223E-03 0,02806442 ! Rac protein signal transduction GO:0016601 6 6 0,000 5,223E-03 0,02798283 ! regulation of vascular permeability GO:0043114 6 6 0,000 5,223E-03 0,02790172 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 5,223E-03 0,02782108 ! ruffle organization GO:0031529 6 6 0,000 5,223E-03 0,02774091 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 5,223E-03 0,02766119 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 5,223E-03 0,02758193 ! retinoic acid metabolic process GO:0042573 6 6 0,000 5,223E-03 0,02750313 ! neutral amino acid transport GO:0015804 6 6 0,000 5,223E-03 0,02742477 ! L-amino acid transport GO:0015807 6 6 0,000 5,223E-03 0,02734686 ! bone mineralization GO:0030282 6 6 0,000 5,223E-03 0,02726939 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 5,223E-03 0,02719236 ! negative regulation of ossification GO:0030279 6 6 0,000 5,223E-03 0,02711576 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 5,223E-03 0,02703959 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 5,223E-03 0,02696385 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 5,223E-03 0,02688853 ! purine base biosynthetic process GO:0009113 6 6 0,000 5,223E-03 0,02681363 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 5,223E-03 0,02673915 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 5,223E-03 0,02666508 ! regulation of phagocytosis GO:0050764 6 6 0,000 5,223E-03 0,02659142 ! regulation of organ growth GO:0046620 6 6 0,000 5,223E-03 0,02651817 ! regulation of circadian rhythm GO:0042752 6 6 0,000 5,223E-03 0,02644531 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 5,223E-03 0,02637286 ! response to dsRNA GO:0043331 6 6 0,000 5,223E-03 0,0263008 ! DNA unwinding during replication GO:0006268 6 6 0,000 5,223E-03 0,02622914 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 5,223E-03 0,02615787 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 5,223E-03 0,02608698 ! genitalia development GO:0048806 6 6 0,000 5,223E-03 0,02601647 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 5,223E-03 0,02594635 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 5,223E-03 0,0258766 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 5,223E-03 0,02580722 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 5,223E-03 0,02573822 ! multicellular organismal aging GO:0010259 6 6 0,000 5,223E-03 0,02566959 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 5,223E-03 0,02560132 ! erythrocyte development GO:0048821 6 6 0,000 5,223E-03 0,02553341 ! renal water homeostasis GO:0003091 6 6 0,000 5,223E-03 0,02546586 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 5,223E-03 0,02539867 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 5,223E-03 0,02533183 ! ribosome assembly GO:0042255 6 6 0,000 5,223E-03 0,02526534 ! diencephalon development GO:0021536 6 6 0,000 5,223E-03 0,0251992 ! fucose catabolic process GO:0019317 6 6 0,000 5,223E-03 0,02513341 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 5,223E-03 0,02506795 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 5,223E-03 0,02500284 ! regulation of lipid transport GO:0032368 6 6 0,000 5,223E-03 0,02493807 ! regulation of cell division GO:0051302 6 6 0,000 5,223E-03 0,02487363 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 5,223E-03 0,02480952 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 5,223E-03 0,02474574 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 5,223E-03 0,02468229 ! salivary gland morphogenesis GO:0007435 6 6 0,000 5,223E-03 0,02461917 ! neuroblast proliferation GO:0007405 6 6 0,000 5,223E-03 0,02455636 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 5,223E-03 0,02449388 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 5,223E-03 0,02443171 ! regulation of glucose transport GO:0010827 6 6 0,000 5,223E-03 0,02436986 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 5,223E-03 0,02430832 ! methionine biosynthetic process GO:0009086 6 6 0,000 5,223E-03 0,02424709 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 5,223E-03 0,02418617 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 5,223E-03 0,02412555 ! thymus development GO:0048538 6 6 0,000 5,223E-03 0,02406524 ! lymph node development GO:0048535 6 6 0,000 5,223E-03 0,02400522 ! organic cation transport GO:0015695 6 6 0,000 5,223E-03 0,02394551 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 5,223E-03 0,02388609 ! regulation of RNA splicing GO:0043484 6 6 0,000 5,223E-03 0,02382697 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 5,223E-03 0,02376813 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 5,223E-03 0,02370959 ! sperm-egg recognition GO:0035036 7 6 0,000 5,223E-03 0,02365134 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 5,223E-03 0,02359337 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 5,223E-03 0,02353568 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 5,223E-03 0,02347828 ! alditol metabolic process GO:0019400 6 6 0,000 5,223E-03 0,02342115 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 5,223E-03 0,02336431 ! regulation of amino acid transport GO:0051955 6 6 0,000 5,223E-03 0,02330774 ! maternal placenta development GO:0001893 6 6 0,000 5,223E-03 0,02325144 ! regulation of embryonic development GO:0045995 6 6 0,000 5,223E-03 0,02319541 ! negative regulation of immune effector process GO:0002698 6 6 0,000 5,223E-03 0,02313965 ! localization within membrane GO:0051668 6 6 0,000 5,223E-03 0,02308416 ! respiratory burst GO:0045730 7 7 0,000 6,091E-03 0,02685733 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 6,091E-03 0,02679323 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 6,091E-03 0,02672944 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 6,091E-03 0,02666594 ! positive regulation of blood pressure GO:0045777 7 7 0,000 6,091E-03 0,02660276 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 6,091E-03 0,02653986 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 6,091E-03 0,02647727 ! regulation of chemokine production GO:0032642 7 7 0,000 6,091E-03 0,02641497 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 6,091E-03 0,02635296 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 6,091E-03 0,02629125 ! hair follicle morphogenesis GO:0031069 7 7 0,000 6,091E-03 0,02622982 ! gene silencing by RNA GO:0031047 7 7 0,000 6,091E-03 0,02616868 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 6,091E-03 0,02610782 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 6,091E-03 0,02604725 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 6,091E-03 0,02598695 ! keratinocyte proliferation GO:0043616 7 7 0,000 6,091E-03 0,02592693 ! axis specification GO:0009798 7 7 0,000 6,091E-03 0,0258672 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 6,091E-03 0,02580773 ! visual behavior GO:0007632 7 7 0,000 6,091E-03 0,02574854 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 6,091E-03 0,02568962 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 6,091E-03 0,02563097 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 6,091E-03 0,02557258 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 6,091E-03 0,02551446 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 6,091E-03 0,0254566 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 6,091E-03 0,02539901 ! endothelial cell differentiation GO:0045446 7 7 0,000 6,091E-03 0,02534168 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 6,091E-03 0,0252846 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 6,091E-03 0,02522778 ! digestive system development GO:0055123 7 7 0,000 6,091E-03 0,02517122 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 6,091E-03 0,02511491 ! regulation of exit from mitosis GO:0007096 7 7 0,000 6,091E-03 0,02505885 ! protein targeting to ER GO:0045047 8 7 0,000 6,091E-03 0,02500304 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 6,091E-03 0,02494747 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 6,091E-03 0,02489216 ! endoderm development GO:0007492 7 7 0,000 6,091E-03 0,02483709 ! regulation of defense response to virus GO:0050688 7 7 0,000 6,091E-03 0,02478226 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 6,091E-03 0,02472767 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 6,091E-03 0,02467332 ! response to hexose stimulus GO:0009746 7 7 0,000 6,091E-03 0,02461922 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 6,091E-03 0,02456535 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 6,091E-03 0,02451171 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 6,091E-03 0,02445831 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 6,091E-03 0,02440514 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 6,091E-03 0,0243522 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 6,091E-03 0,02429949 ! complement activation, alternative pathway GO:0006957 7 7 0,000 6,091E-03 0,024247 ! arachidonic acid secretion GO:0050482 7 7 0,000 6,091E-03 0,02419475 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 6,091E-03 0,02414272 ! response to X-ray GO:0010165 7 7 0,000 6,091E-03 0,02409091 ! regulation of intracellular pH GO:0051453 7 7 0,000 6,091E-03 0,02403932 ! UV protection GO:0009650 7 7 0,000 6,091E-03 0,02398795 ! DNA integration GO:0015074 7 7 0,000 6,091E-03 0,02393681 ! myofibril assembly GO:0030239 7 7 0,000 6,091E-03 0,02388588 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 6,091E-03 0,02383517 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 6,091E-03 0,02378467 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 6,091E-03 0,02373438 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 6,091E-03 0,02368431 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 6,091E-03 0,02363445 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 6,091E-03 0,0235848 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 6,091E-03 0,02353535 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 6,091E-03 0,02348611 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 6,091E-03 0,02343708 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 6,091E-03 0,02338826 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 6,091E-03 0,02333963 ! axon cargo transport GO:0008088 7 7 0,000 6,091E-03 0,02329121 ! eating behavior GO:0042755 7 7 0,000 6,091E-03 0,02324299 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 6,091E-03 0,02319496 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 6,091E-03 0,02314714 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 6,091E-03 0,02309951 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 6,091E-03 0,02305208 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 6,091E-03 0,02300484 ! cranial nerve development GO:0021545 7 7 0,000 6,091E-03 0,0229578 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 6,091E-03 0,02291094 ! induction of an organ GO:0001759 7 7 0,000 6,091E-03 0,02286428 ! leukocyte activation during immune response GO:0002366 7 7 0,000 6,091E-03 0,02281781 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 6,091E-03 0,02277153 ! autonomic nervous system development GO:0048483 7 7 0,000 6,091E-03 0,02272543 ! intracellular lipid transport GO:0032365 7 7 0,000 6,091E-03 0,02267952 ! detection of chemical stimulus GO:0009593 8 7 0,000 6,091E-03 0,0226338 ! platelet activation GO:0030168 8 7 0,000 6,091E-03 0,02258826 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 6,091E-03 0,0225429 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 6,091E-03 0,02249772 ! natural killer cell activation GO:0030101 7 7 0,000 6,091E-03 0,02245273 ! response to gamma radiation GO:0010332 8 7 0,000 6,091E-03 0,02240791 ! NADP metabolic process GO:0006739 7 7 0,000 6,091E-03 0,02236327 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 6,091E-03 0,02231881 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 6,091E-03 0,02227453 ! ubiquinone metabolic process GO:0006743 7 7 0,000 6,091E-03 0,02223042 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 6,091E-03 0,02218649 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 6,091E-03 0,02214273 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 6,091E-03 0,02209914 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 6,091E-03 0,02205572 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 6,091E-03 0,02201248 ! regulation of ATPase activity GO:0043462 7 7 0,000 6,091E-03 0,0219694 ! cell-cell recognition GO:0009988 8 7 0,000 6,091E-03 0,02192649 ! hormone catabolic process GO:0042447 7 7 0,000 6,091E-03 0,02188375 ! dopamine metabolic process GO:0042417 7 7 0,000 6,091E-03 0,02184117 ! cAMP biosynthetic process GO:0006171 7 7 0,000 6,091E-03 0,02179876 ! oxygen transport GO:0015671 7 7 0,000 6,091E-03 0,02175652 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 6,091E-03 0,02171443 ! regulation of mRNA stability GO:0043488 7 7 0,000 6,091E-03 0,02167252 ! biogenic amine catabolic process GO:0042402 7 7 0,000 6,091E-03 0,02163076 ! regulation of axon extension GO:0030516 7 7 0,000 6,091E-03 0,02158916 ! cell killing GO:0001906 7 7 0,000 6,091E-03 0,02154772 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 6,091E-03 0,02150644 ! adult feeding behavior GO:0008343 7 7 0,000 6,091E-03 0,02146532 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 6,091E-03 0,02142436 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 6,091E-03 0,02138355 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 6,091E-03 0,0213429 ! negative regulation of T cell activation GO:0050868 7 7 0,000 6,091E-03 0,0213024 ! response to cold GO:0009409 7 7 0,000 6,091E-03 0,02126205 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 6,959E-03 0,02424474 ! negative regulation of muscle development GO:0048635 8 8 0,000 6,959E-03 0,02419899 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 6,959E-03 0,02415342 ! positive regulation of translation GO:0045727 8 8 0,000 6,959E-03 0,02410802 ! positive regulation of cell killing GO:0031343 8 8 0,000 6,959E-03 0,02406279 ! superoxide anion generation GO:0042554 8 8 0,000 6,959E-03 0,02401773 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 6,959E-03 0,02397284 ! cGMP metabolic process GO:0046068 8 8 0,000 6,959E-03 0,02392811 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 6,959E-03 0,02388355 ! 'de novo' protein folding GO:0006458 8 8 0,000 6,959E-03 0,02383916 ! dicarboxylic acid transport GO:0006835 8 8 0,000 6,959E-03 0,02379493 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 6,959E-03 0,02375086 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 6,959E-03 0,02370696 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 6,959E-03 0,02366322 ! zinc ion transport GO:0006829 8 8 0,000 6,959E-03 0,02361964 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 6,959E-03 0,02357623 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 6,959E-03 0,02353297 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 6,959E-03 0,02348987 ! cardiac muscle contraction GO:0060048 8 8 0,000 6,959E-03 0,02344692 ! lipid localization GO:0010876 8 8 0,000 6,959E-03 0,02340414 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 6,959E-03 0,02336151 ! response to cAMP GO:0051591 8 8 0,000 6,959E-03 0,02331903 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 6,959E-03 0,02327671 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 6,959E-03 0,02323454 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 6,959E-03 0,02319253 ! negative regulation of ion transport GO:0043271 8 8 0,000 6,959E-03 0,02315066 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 6,959E-03 0,02310895 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 6,959E-03 0,02306739 ! sensory perception of taste GO:0050909 8 8 0,000 6,959E-03 0,02302597 ! organelle fusion GO:0048284 8 8 0,000 6,959E-03 0,02298471 ! pancreas development GO:0031016 8 8 0,000 6,959E-03 0,02294359 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 6,959E-03 0,02290262 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 6,959E-03 0,02286179 ! negative regulation of proteolysis GO:0045861 8 8 0,000 6,959E-03 0,02282112 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 6,959E-03 0,02278058 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 6,959E-03 0,02274019 ! sperm motility GO:0030317 8 8 0,000 6,959E-03 0,02269994 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 6,959E-03 0,02265984 ! DNA duplex unwinding GO:0032508 8 8 0,000 6,959E-03 0,02261987 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 6,959E-03 0,02258005 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 6,959E-03 0,02254036 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 6,959E-03 0,02250082 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 6,959E-03 0,02246141 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 6,959E-03 0,02242214 ! Golgi organization GO:0007030 8 8 0,000 6,959E-03 0,02238301 ! cell-cell junction assembly GO:0007043 8 8 0,000 6,959E-03 0,02234402 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 6,959E-03 0,02230516 ! fructose metabolic process GO:0006000 8 8 0,000 6,959E-03 0,02226644 ! mannose metabolic process GO:0006013 9 8 0,000 6,959E-03 0,02222785 ! NAD metabolic process GO:0019674 8 8 0,000 6,959E-03 0,02218939 ! sex determination GO:0007530 8 8 0,000 6,959E-03 0,02215107 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 6,959E-03 0,02211287 ! plasma membrane fusion GO:0045026 8 8 0,000 6,959E-03 0,02207481 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 6,959E-03 0,02203688 ! response to fungus GO:0009620 8 8 0,000 6,959E-03 0,02199909 ! stem cell differentiation GO:0048863 8 8 0,000 6,959E-03 0,02196142 ! alpha-beta T cell activation GO:0046631 8 8 0,000 6,959E-03 0,02192387 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 6,959E-03 0,02188646 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 6,959E-03 0,02184918 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 6,959E-03 0,02181202 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 6,959E-03 0,02177499 ! regulation of vasodilation GO:0042312 8 8 0,000 6,959E-03 0,02173808 ! vasoconstriction GO:0042310 8 8 0,000 6,959E-03 0,0217013 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 6,959E-03 0,02166464 ! muscle cell development GO:0055001 8 8 0,000 6,959E-03 0,02162811 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 6,959E-03 0,02159169 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 6,959E-03 0,02155541 ! sensory perception of pain GO:0019233 8 8 0,000 6,959E-03 0,02151924 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 6,959E-03 0,02148319 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 6,959E-03 0,02144727 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 6,959E-03 0,02141146 ! chromatin silencing GO:0006342 8 8 0,000 6,959E-03 0,02137578 ! tissue regeneration GO:0042246 8 8 0,000 6,959E-03 0,02134021 ! salivary gland development GO:0007431 8 8 0,000 6,959E-03 0,02130476 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 6,959E-03 0,02126943 ! T cell homeostasis GO:0043029 8 8 0,000 6,959E-03 0,02123422 ! peptide biosynthetic process GO:0043043 9 8 0,000 6,959E-03 0,02119912 ! peptidyl-serine modification GO:0018209 8 8 0,000 6,959E-03 0,02116414 ! water homeostasis GO:0030104 8 8 0,000 6,959E-03 0,02112927 ! cofactor transport GO:0051181 8 8 0,000 6,959E-03 0,02109452 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 6,959E-03 0,02105988 ! acid secretion GO:0046717 8 8 0,000 6,959E-03 0,02102536 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 6,959E-03 0,02099094 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 6,959E-03 0,02095665 ! protein-chromophore linkage GO:0018298 9 8 0,000 6,959E-03 0,02092246 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 6,959E-03 0,02088838 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 6,959E-03 0,02085442 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 6,959E-03 0,02082056 ! regulation of RNA stability GO:0043487 8 8 0,000 6,959E-03 0,02078682 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 6,959E-03 0,02075318 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 6,959E-03 0,02071966 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 6,959E-03 0,02068624 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 6,959E-03 0,02065293 ! regulation of organic acid transport GO:0032890 8 8 0,000 6,959E-03 0,02061972 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 6,959E-03 0,02058662 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 6,959E-03 0,02055363 ! regulation of multi-organism process GO:0043900 8 8 0,000 6,959E-03 0,02052075 ! positive regulation of amine transport GO:0051954 8 8 0,000 6,959E-03 0,02048797 ! developmental induction GO:0031128 8 8 0,000 6,959E-03 0,02045529 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 6,959E-03 0,02042272 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 6,959E-03 0,02039025 ! actin filament polymerization GO:0030041 9 8 0,000 6,959E-03 0,02035788 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 6,959E-03 0,02032562 ! peptide hormone processing GO:0016486 8 8 0,000 6,959E-03 0,02029346 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 6,959E-03 0,0202614 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 6,959E-03 0,02022944 ! lactation GO:0007595 10 9 0,000 7,826E-03 0,02271403 ! embryonic pattern specification GO:0009880 10 9 0,000 7,826E-03 0,02267831 ! positive regulation of cell size GO:0045793 9 9 0,000 7,826E-03 0,02264271 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 7,826E-03 0,02260722 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 7,826E-03 0,02257184 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 7,826E-03 0,02253657 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 7,826E-03 0,02250142 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 7,826E-03 0,02246637 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 7,826E-03 0,02243143 ! viral genome replication GO:0019079 9 9 0,000 7,826E-03 0,0223966 ! phospholipid catabolic process GO:0009395 9 9 0,000 7,826E-03 0,02236187 ! copper ion transport GO:0006825 9 9 0,000 7,826E-03 0,02232726 ! lipid phosphorylation GO:0046834 9 9 0,000 7,826E-03 0,02229275 ! aminoglycan catabolic process GO:0006026 9 9 0,000 7,826E-03 0,02225834 ! Golgi vesicle budding GO:0048194 9 9 0,000 7,826E-03 0,02222405 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 7,826E-03 0,02218986 ! RNA polyadenylation GO:0043631 9 9 0,000 7,826E-03 0,02215577 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 7,826E-03 0,02212179 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 7,826E-03 0,02208791 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 7,826E-03 0,02205414 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 7,826E-03 0,02202047 ! phospholipid efflux GO:0033700 9 9 0,000 7,826E-03 0,0219869 ! response to alkaloid GO:0043279 10 9 0,000 7,826E-03 0,02195344 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 7,826E-03 0,02192007 ! cytokine biosynthetic process GO:0042089 9 9 0,000 7,826E-03 0,02188681 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 7,826E-03 0,02185365 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 7,826E-03 0,02182059 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 7,826E-03 0,02178762 ! response to ethanol GO:0045471 9 9 0,000 7,826E-03 0,02175476 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 7,826E-03 0,021722 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 7,826E-03 0,02168933 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 7,826E-03 0,02165677 ! methionine metabolic process GO:0006555 9 9 0,000 7,826E-03 0,0216243 ! glutamine metabolic process GO:0006541 9 9 0,000 7,826E-03 0,02159193 ! cerebral cortex development GO:0021987 9 9 0,000 7,826E-03 0,02155965 ! response to osmotic stress GO:0006970 9 9 0,000 7,826E-03 0,02152747 ! pigmentation during development GO:0048066 9 9 0,000 7,826E-03 0,02149539 ! reverse cholesterol transport GO:0043691 9 9 0,000 7,826E-03 0,0214634 ! central nervous system neuron development GO:0021954 10 9 0,000 7,826E-03 0,02143151 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 7,826E-03 0,02139971 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 7,826E-03 0,02136801 ! substrate-bound cell migration GO:0006929 9 9 0,000 7,826E-03 0,0213364 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 7,826E-03 0,02130489 ! negative regulation of caspase activity GO:0043154 9 9 0,000 7,826E-03 0,02127346 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 7,826E-03 0,02124213 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 7,826E-03 0,02121089 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 7,826E-03 0,02117975 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 7,826E-03 0,02114869 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 7,826E-03 0,02111773 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 7,826E-03 0,02108685 ! behavioral interaction between organisms GO:0051705 9 9 0,000 7,826E-03 0,02105607 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 7,826E-03 0,02102538 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 7,826E-03 0,02099477 ! DNA replication initiation GO:0006270 9 9 0,000 7,826E-03 0,02096425 ! prostaglandin metabolic process GO:0006693 9 9 0,000 7,826E-03 0,02093383 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 7,826E-03 0,02090349 ! regulation of cellular pH GO:0030641 9 9 0,000 7,826E-03 0,02087324 ! histone acetylation GO:0016573 9 9 0,000 7,826E-03 0,02084307 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 7,826E-03 0,020813 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 7,826E-03 0,02078301 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 7,826E-03 0,0207531 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 7,826E-03 0,02072329 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 7,826E-03 0,02069355 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 7,826E-03 0,02066391 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 7,826E-03 0,02063435 ! negative regulation of protein secretion GO:0050709 9 9 0,000 7,826E-03 0,02060487 ! regulation of leukocyte migration GO:0002685 9 9 0,000 7,826E-03 0,02057547 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 7,826E-03 0,02054616 ! collagen catabolic process GO:0030574 9 9 0,000 7,826E-03 0,02051694 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 7,826E-03 0,02048779 ! purine base metabolic process GO:0006144 9 9 0,000 7,826E-03 0,02045873 ! gas transport GO:0015669 9 9 0,000 7,826E-03 0,02042976 ! cholesterol efflux GO:0033344 9 9 0,000 7,826E-03 0,02040086 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 7,826E-03 0,02037204 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 7,826E-03 0,02034331 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 7,826E-03 0,02031466 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 7,826E-03 0,02028609 ! defense response to virus GO:0051607 9 9 0,000 7,826E-03 0,02025759 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 7,826E-03 0,02022918 ! actin filament-based movement GO:0030048 9 9 0,000 7,826E-03 0,02020085 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 7,826E-03 0,0201726 ! protein import into nucleus, docking GO:0000059 10 10 0,000 8,692E-03 0,02237456 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 8,692E-03 0,02234335 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 8,692E-03 0,02231224 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 8,692E-03 0,0222812 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 8,692E-03 0,02225026 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 8,692E-03 0,0222194 ! neuron maturation GO:0042551 10 10 0,000 8,692E-03 0,02218862 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 8,692E-03 0,02215793 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 8,692E-03 0,02212733 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 8,692E-03 0,02209681 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 8,692E-03 0,02206637 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 8,692E-03 0,02203602 ! hormone secretion GO:0046879 10 10 0,000 8,692E-03 0,02200575 ! glucosamine metabolic process GO:0006041 10 10 0,000 8,692E-03 0,02197556 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 8,692E-03 0,02194546 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 8,692E-03 0,02191544 ! inositol metabolic process GO:0006020 10 10 0,000 8,692E-03 0,0218855 ! cAMP metabolic process GO:0046058 10 10 0,000 8,692E-03 0,02185564 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 8,692E-03 0,02182587 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 8,692E-03 0,02179617 ! forelimb morphogenesis GO:0035136 10 10 0,000 8,692E-03 0,02176656 ! glial cell development GO:0021782 10 10 0,000 8,692E-03 0,02173702 ! phototransduction GO:0007602 11 10 0,000 8,692E-03 0,02170757 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 8,692E-03 0,02167819 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 8,692E-03 0,0216489 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 8,692E-03 0,02161968 ! fat cell differentiation GO:0045444 10 10 0,000 8,692E-03 0,02159055 ! myoblast differentiation GO:0045445 10 10 0,000 8,692E-03 0,02156149 ! centrosome cycle GO:0007098 10 10 0,000 8,692E-03 0,02153251 ! inactivation of MAPK activity GO:0000188 10 10 0,000 8,692E-03 0,0215036 ! positive regulation of proteolysis GO:0045862 10 10 0,000 8,692E-03 0,02147478 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 8,692E-03 0,02144603 ! regulation of survival gene product expression GO:0045884 10 10 0,000 8,692E-03 0,02141736 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 8,692E-03 0,02138877 ! epidermis morphogenesis GO:0048730 10 10 0,000 8,692E-03 0,02136025 ! protein polyubiquitination GO:0000209 10 10 0,000 8,692E-03 0,0213318 ! glutamate metabolic process GO:0006536 11 10 0,000 8,692E-03 0,02130344 ! plasma membrane organization GO:0007009 10 10 0,000 8,692E-03 0,02127515 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 8,692E-03 0,02124693 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 8,692E-03 0,02121879 ! lysosomal transport GO:0007041 10 10 0,000 8,692E-03 0,02119072 ! cellular response to unfolded protein GO:0034620 10 10 0,000 8,692E-03 0,02116273 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 8,692E-03 0,02113481 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 8,692E-03 0,02110696 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 8,692E-03 0,02107919 ! exocrine system development GO:0035272 10 10 0,000 8,692E-03 0,02105149 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 8,692E-03 0,02102386 ! neuromuscular junction development GO:0007528 10 10 0,000 8,692E-03 0,02099631 ! embryo implantation GO:0007566 11 10 0,000 8,692E-03 0,02096883 ! regulation of protein binding GO:0043393 11 10 0,000 8,692E-03 0,02094142 ! protein targeting to peroxisome GO:0006625 10 10 0,000 8,692E-03 0,02091408 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 8,692E-03 0,02088681 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 8,692E-03 0,02085962 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 8,692E-03 0,02083249 ! protein export from nucleus GO:0006611 10 10 0,000 8,692E-03 0,02080544 ! negative regulation of immune response GO:0050777 10 10 0,000 8,692E-03 0,02077845 ! cytolysis GO:0019835 10 10 0,000 8,692E-03 0,02075153 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 8,692E-03 0,02072469 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 8,692E-03 0,02069791 ! regulation of B cell differentiation GO:0045577 10 10 0,000 8,692E-03 0,02067121 ! histone deacetylation GO:0016575 10 10 0,000 8,692E-03 0,02064457 ! mRNA splice site selection GO:0006376 11 10 0,000 8,692E-03 0,020618 ! synaptic vesicle transport GO:0048489 11 10 0,000 8,692E-03 0,0205915 ! gland morphogenesis GO:0022612 10 10 0,000 8,692E-03 0,02056506 ! positive regulation of neurological system process GO:0031646 10 10 0,000 8,692E-03 0,0205387 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 8,692E-03 0,0205124 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 8,692E-03 0,02048617 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 8,692E-03 0,02046001 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 8,692E-03 0,02043391 ! regulation of epidermis development GO:0045682 10 10 0,000 8,692E-03 0,02040788 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 8,692E-03 0,02038191 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 8,692E-03 0,02035602 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 8,692E-03 0,02033018 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 8,692E-03 0,02030442 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 8,692E-03 0,02027872 ! lymphocyte homeostasis GO:0002260 10 10 0,000 8,692E-03 0,02025308 ! nerve development GO:0021675 10 10 0,000 8,692E-03 0,02022751 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 8,692E-03 0,020202 ! gut development GO:0048565 10 10 0,000 8,692E-03 0,02017656 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 8,692E-03 0,02015118 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 8,692E-03 0,02012586 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 8,692E-03 0,02010061 ! mRNA 3'-end processing GO:0031124 10 10 0,000 8,692E-03 0,02007542 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 8,692E-03 0,02005029 ! negative regulation of coagulation GO:0050819 11 10 0,000 8,692E-03 0,02002523 ! protein stabilization GO:0050821 10 10 0,000 8,692E-03 0,02000023 ! protein secretion GO:0009306 11 11 0,000 9,558E-03 0,02196484 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 9,558E-03 0,02193749 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 9,558E-03 0,0219102 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 9,558E-03 0,02188298 ! negative regulation of defense response GO:0031348 11 11 0,000 9,558E-03 0,02185583 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 9,558E-03 0,02182875 ! determination of bilateral symmetry GO:0009855 11 11 0,000 9,558E-03 0,02180173 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 9,558E-03 0,02177478 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 9,558E-03 0,0217479 ! skin development GO:0043588 11 11 0,000 9,558E-03 0,02172109 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 9,558E-03 0,02169434 ! signal complex assembly GO:0007172 11 11 0,000 9,558E-03 0,02166765 ! microtubule-based transport GO:0010970 11 11 0,000 9,558E-03 0,02164103 ! endothelial cell migration GO:0043542 11 11 0,000 9,558E-03 0,02161448 ! peroxisomal transport GO:0043574 11 11 0,000 9,558E-03 0,02158799 ! protein amino acid methylation GO:0006479 11 11 0,000 9,558E-03 0,02156157 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 9,558E-03 0,02153521 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 9,558E-03 0,02150891 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 9,558E-03 0,02148268 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 9,558E-03 0,02145652 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 9,558E-03 0,02143041 ! T cell proliferation GO:0042098 11 11 0,000 9,558E-03 0,02140437 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 9,558E-03 0,0213784 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 9,558E-03 0,02135249 ! regulation of viral genome replication GO:0045069 11 11 0,000 9,558E-03 0,02132664 ! spinal cord development GO:0021510 11 11 0,000 9,558E-03 0,02130085 ! activation of MAPKK activity GO:0000186 12 11 0,000 9,558E-03 0,02127512 ! smooth muscle contraction GO:0006939 11 11 0,000 9,558E-03 0,02124946 ! cellular response to starvation GO:0009267 11 11 0,000 9,558E-03 0,02122386 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 9,558E-03 0,02119832 ! digestive system process GO:0022600 11 11 0,000 9,558E-03 0,02117284 ! fucose metabolic process GO:0006004 11 11 0,000 9,558E-03 0,02114742 ! membrane budding GO:0006900 11 11 0,000 9,558E-03 0,02112206 ! apoptotic nuclear changes GO:0030262 11 11 0,000 9,558E-03 0,02109677 ! monoamine transport GO:0015844 11 11 0,000 9,558E-03 0,02107153 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 9,558E-03 0,02104636 ! response to lipopolysaccharide GO:0032496 11 11 0,000 9,558E-03 0,02102124 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 9,558E-03 0,02099619 ! body fluid secretion GO:0007589 11 11 0,000 9,558E-03 0,02097119 ! G1/S transition checkpoint GO:0031575 12 11 0,000 9,558E-03 0,02094626 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 9,558E-03 0,02092138 ! intermediate filament-based process GO:0045103 11 11 0,000 9,558E-03 0,02089656 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 9,558E-03 0,0208718 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 9,558E-03 0,0208471 ! membrane depolarization GO:0051899 11 11 0,000 9,558E-03 0,02082246 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 9,558E-03 0,02079788 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 9,558E-03 0,02077335 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 9,558E-03 0,02074888 ! oogenesis GO:0048477 11 11 0,000 9,558E-03 0,02072447 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 9,558E-03 0,02070012 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 9,558E-03 0,02067582 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 9,558E-03 0,02065158 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 9,558E-03 0,0206274 ! muscle maintenance GO:0046716 12 11 0,000 9,558E-03 0,02060328 ! vitamin A metabolic process GO:0006776 11 11 0,000 9,558E-03 0,02057921 ! hindbrain development GO:0030902 11 11 0,000 9,558E-03 0,02055519 ! steroid catabolic process GO:0006706 11 11 0,000 9,558E-03 0,02053124 ! endocrine process GO:0050886 11 11 0,000 9,558E-03 0,02050733 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 9,558E-03 0,02048349 ! proximal/distal pattern formation GO:0009954 11 11 0,000 9,558E-03 0,0204597 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 9,558E-03 0,02043596 ! RNA 3'-end processing GO:0031123 11 11 0,000 9,558E-03 0,02041228 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 9,558E-03 0,02038866 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,01042336 0,02220839 ! translational initiation GO:0006413 12 12 0,000 0,01042336 0,02218274 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,01042336 0,02215716 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,01042336 0,02213163 ! initiation of viral infection GO:0019059 12 12 0,000 0,01042336 0,02210616 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,01042336 0,02208075 ! iron ion transport GO:0006826 13 12 0,000 0,01042336 0,0220554 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,01042336 0,02203011 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,01042336 0,02200487 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,01042336 0,0219797 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,01042336 0,02195458 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,01042336 0,02192951 ! collagen metabolic process GO:0032963 12 12 0,000 0,01042336 0,02190451 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,01042336 0,02187956 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,01042336 0,02185467 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,01042336 0,02182983 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,01042336 0,02180506 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,01042336 0,02178033 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,01042336 0,02175567 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,01042336 0,02173106 ! actomyosin structure organization GO:0031032 12 12 0,000 0,01042336 0,0217065 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,01042336 0,021682 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,01042336 0,02165756 ! retinoid metabolic process GO:0001523 12 12 0,000 0,01042336 0,02163317 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,01042336 0,02160884 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,01042336 0,02158456 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,01042336 0,02156033 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,01042336 0,02153616 ! acute-phase response GO:0006953 12 12 0,000 0,01042336 0,02151204 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01042336 0,02148798 ! vacuolar transport GO:0007034 12 12 0,000 0,01042336 0,02146397 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,01042336 0,02144002 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,01042336 0,02141611 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,01042336 0,02139227 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,01042336 0,02136847 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,01042336 0,02134473 ! male gonad development GO:0008584 12 12 0,000 0,01042336 0,02132104 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,01042336 0,0212974 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,01042336 0,02127381 ! renal system process GO:0003014 12 12 0,000 0,01042336 0,02125028 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,01042336 0,0212268 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,01042336 0,02120337 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,01042336 0,02117999 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,01042336 0,02115667 ! pallium development GO:0021543 13 12 0,000 0,01042336 0,02113339 ! cell fate determination GO:0001709 12 12 0,000 0,01042336 0,02111017 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,01042336 0,021087 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,01042336 0,02106388 ! somitogenesis GO:0001756 13 12 0,000 0,01042336 0,0210408 ! G1 phase GO:0051318 13 12 0,000 0,01042336 0,02101778 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,01042336 0,02099481 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,01042336 0,02097189 ! detection of light stimulus GO:0009583 13 12 0,000 0,01042336 0,02094902 ! synaptogenesis GO:0007416 12 12 0,000 0,01042336 0,0209262 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,01042336 0,02090343 ! hormone transport GO:0009914 12 12 0,000 0,01042336 0,02088071 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,01042336 0,02085804 ! heme biosynthetic process GO:0006783 12 12 0,000 0,01042336 0,02083542 ! spermatid differentiation GO:0048515 13 12 0,000 0,01042336 0,02081284 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,01042336 0,02079032 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,01042336 0,02076784 ! neural tube closure GO:0001843 13 12 0,000 0,01042336 0,02074542 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,01042336 0,02072304 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,01042336 0,02070071 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,01042336 0,02067842 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,01128787 0,02236941 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,01128787 0,02234538 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,01128787 0,0223214 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,01128787 0,02229748 ! phenol metabolic process GO:0018958 13 13 0,000 0,01128787 0,02227361 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,01128787 0,02224978 ! gluconeogenesis GO:0006094 13 13 0,000 0,01128787 0,02222601 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,01128787 0,02220229 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,01128787 0,02217862 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,01128787 0,022155 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,01128787 0,02213143 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,01128787 0,02210791 ! regeneration GO:0031099 13 13 0,000 0,01128787 0,02208445 ! keratinization GO:0031424 13 13 0,000 0,01128787 0,02206103 ! post-embryonic development GO:0009791 14 13 0,000 0,01128787 0,02203766 ! patterning of blood vessels GO:0001569 13 13 0,000 0,01128787 0,02201434 ! vasculogenesis GO:0001570 13 13 0,000 0,01128787 0,02199107 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,01128787 0,02196784 ! regulation of innate immune response GO:0045088 13 13 0,000 0,01128787 0,02194467 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,01128787 0,02192155 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,01128787 0,02189847 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,01128787 0,02187544 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,01128787 0,02185247 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,01128787 0,02182954 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,01128787 0,02180665 ! autophagy GO:0006914 13 13 0,000 0,01128787 0,02178382 ! receptor metabolic process GO:0043112 14 13 0,000 0,01128787 0,02176103 ! actin filament bundle formation GO:0051017 13 13 0,000 0,01128787 0,02173829 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,01128787 0,0217156 ! ureteric bud development GO:0001657 13 13 0,000 0,01128787 0,02169296 ! cell aging GO:0007569 13 13 0,000 0,01128787 0,02167036 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,01128787 0,02164781 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,01128787 0,02162531 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,01128787 0,02160285 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,01128787 0,02158044 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,01128787 0,02155808 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,01128787 0,02153576 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,01128787 0,02151349 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,01128787 0,02149127 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,01128787 0,02146909 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,01128787 0,02144696 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,01128787 0,02142487 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,01128787 0,02140283 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,01128787 0,02138083 ! vasodilation GO:0042311 14 13 0,000 0,01128787 0,02135888 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,01128787 0,02133697 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,01128787 0,02131511 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,01128787 0,02129329 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,01128787 0,02127152 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,01128787 0,02124979 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,01128787 0,02122811 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,01128787 0,02120647 ! immunoglobulin production GO:0002377 13 13 0,000 0,01128787 0,02118488 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,01128787 0,02116332 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,01128787 0,02114182 ! cell-cell junction organization GO:0045216 13 13 0,000 0,01128787 0,02112035 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,01128787 0,02109893 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,01128787 0,02107756 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,01128787 0,02105622 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,01128787 0,02103493 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,01128787 0,02101368 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,01128787 0,02099248 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,01128787 0,02097132 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,01128787 0,0209502 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,01128787 0,02092912 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,01128787 0,02090809 ! blastocyst development GO:0001824 13 13 0,000 0,01128787 0,0208871 ! telomere organization GO:0032200 13 13 0,000 0,01128787 0,02086615 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,01128787 0,02084524 ! regulation of amine transport GO:0051952 13 13 0,000 0,01128787 0,02082437 ! tissue homeostasis GO:0001894 13 13 0,000 0,01128787 0,02080355 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,01128787 0,02078277 ! protein tetramerization GO:0051262 13 13 0,000 0,01128787 0,02076202 ! neuron fate commitment GO:0048663 14 14 0,000 0,01215175 0,0223287 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,01215175 0,02230646 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,01215175 0,02228426 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,01215175 0,02226211 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,01215175 0,02224 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,01215175 0,02221794 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,01215175 0,02219592 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,01215175 0,02217394 ! protein amino acid acylation GO:0043543 14 14 0,000 0,01215175 0,02215201 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,01215175 0,02213012 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,01215175 0,02210827 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,01215175 0,02208647 ! vesicle docking GO:0048278 14 14 0,000 0,01215175 0,02206471 ! superoxide metabolic process GO:0006801 15 14 0,000 0,01215175 0,02204299 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,01215175 0,02202132 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,01215175 0,02199969 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,01215175 0,0219781 ! hair cycle GO:0042633 14 14 0,000 0,01215175 0,02195655 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,01215175 0,02193505 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,01215175 0,02191358 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,01215175 0,02189216 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,01215175 0,02187078 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,01215175 0,02184945 ! lysosome organization GO:0007040 14 14 0,000 0,01215175 0,02182815 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,01215175 0,0218069 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,01215175 0,02178568 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,01215175 0,02176451 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,01215175 0,02174338 ! primary neural tube formation GO:0014020 15 14 0,000 0,01215175 0,02172229 ! peptide cross-linking GO:0018149 14 14 0,000 0,01215175 0,02170124 ! regulation of behavior GO:0050795 14 14 0,000 0,01215175 0,02168023 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,01215175 0,02165927 ! base-excision repair GO:0006284 14 14 0,000 0,01215175 0,02163834 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,01215175 0,02161745 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,01215175 0,02159661 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,01215175 0,0215758 ! formation of primary germ layer GO:0001704 14 14 0,000 0,01215175 0,02155503 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,01215175 0,02153431 ! collagen fibril organization GO:0030199 14 14 0,000 0,01215175 0,02151362 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,01215175 0,02149298 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,01215175 0,02147237 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,01215175 0,0214518 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,01215175 0,02143127 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,01215175 0,02141079 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,01215175 0,02139034 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,01215175 0,02136992 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,01215175 0,02134955 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,01215175 0,02132922 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,01301501 0,0228227 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,01301501 0,022801 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,01301501 0,02277935 ! positive regulation of ossification GO:0045778 15 15 0,000 0,01301501 0,02275774 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,01301501 0,02273617 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,01301501 0,02271464 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,01301501 0,02269315 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,01301501 0,0226717 ! response to vitamin GO:0033273 15 15 0,000 0,01301501 0,02265029 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,01301501 0,02262892 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,01301501 0,02260759 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,01301501 0,0225863 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,01301501 0,02256506 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,01301501 0,02254385 ! ovarian follicle development GO:0001541 15 15 0,000 0,01301501 0,02252268 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,01301501 0,02250155 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,01301501 0,02248046 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,01301501 0,02245941 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,01301501 0,0224384 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,01301501 0,02241743 ! heme metabolic process GO:0042168 15 15 0,000 0,01301501 0,0223965 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,01301501 0,02237561 ! chromosome condensation GO:0030261 15 15 0,000 0,01301501 0,02235476 ! response to starvation GO:0042594 15 15 0,000 0,01301501 0,02233394 ! response to ionizing radiation GO:0010212 16 15 0,000 0,01301501 0,02231317 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,01301501 0,02229243 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,01301501 0,02227173 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,01301501 0,02225107 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,01301501 0,02223045 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,01301501 0,02220987 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,01301501 0,02218932 ! phospholipid transport GO:0015914 15 15 0,000 0,01301501 0,02216881 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,01301501 0,02214834 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,01301501 0,02212791 ! glutathione metabolic process GO:0006749 16 15 0,000 0,01301501 0,02210752 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,01301501 0,02208716 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,01301501 0,02206684 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,01301501 0,02204656 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,01301501 0,02202631 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,01301501 0,02200611 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,01301501 0,02198593 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,01301501 0,0219658 ! protein homooligomerization GO:0051260 15 15 0,000 0,01301501 0,0219457 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,01301501 0,02192564 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,01387763 0,02335751 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,01387763 0,0233362 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,01387763 0,02331492 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,01387763 0,02329369 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,01387763 0,02327249 ! learning GO:0007612 16 16 0,000 0,01387763 0,02325134 ! circadian rhythm GO:0007623 16 16 0,000 0,01387763 0,02323022 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,01387763 0,02320914 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,01387763 0,0231881 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,01387763 0,02316709 ! vacuole organization GO:0007033 16 16 0,000 0,01387763 0,02314613 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,01387763 0,0231252 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,01387763 0,02310431 ! vesicle targeting GO:0006903 17 16 0,000 0,01387763 0,02308346 ! segmentation GO:0035282 17 16 0,000 0,01387763 0,02306264 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,01387763 0,02304186 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,01387763 0,02302113 ! iron ion homeostasis GO:0055072 16 16 0,000 0,01387763 0,02300042 ! positive regulation of cell development GO:0010720 16 16 0,000 0,01387763 0,02297976 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,01387763 0,02295913 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,01387763 0,02293854 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,01387763 0,02291798 ! cell fate specification GO:0001708 16 16 0,000 0,01387763 0,02289747 ! pentose metabolic process GO:0019321 16 16 0,000 0,01387763 0,02287699 ! fatty acid transport GO:0015908 16 16 0,000 0,01387763 0,02285654 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,01387763 0,02283613 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,01387763 0,02281576 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,01387763 0,02279543 ! cofactor catabolic process GO:0051187 16 16 0,000 0,01387763 0,02277513 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,01387763 0,02275487 ! polyol metabolic process GO:0019751 16 16 0,000 0,01387763 0,02273464 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,01387763 0,02271445 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,01387763 0,02269429 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,01387763 0,02267418 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,01387763 0,02265409 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,01387763 0,02263404 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,01387763 0,02261403 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,01387763 0,02259405 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,01387763 0,02257411 ! regulation of coagulation GO:0050818 17 16 0,000 0,01387763 0,02255421 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,01473962 0,02393403 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,01473962 0,02391296 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,01473962 0,02389193 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,01473962 0,02387094 ! myelination GO:0042552 17 17 0,000 0,01473962 0,02384998 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,01473962 0,02382906 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,01473962 0,02380817 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,01473962 0,02378733 ! leukocyte adhesion GO:0007159 17 17 0,000 0,01473962 0,02376652 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,01473962 0,02374574 ! sensory perception of smell GO:0007608 17 17 0,000 0,01473962 0,023725 ! glucose transport GO:0015758 17 17 0,000 0,01473962 0,0237043 ! cell junction assembly GO:0034329 18 17 0,000 0,01473962 0,02368363 ! tissue remodeling GO:0048771 17 17 0,000 0,01473962 0,023663 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,01473962 0,02364241 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,01473962 0,02362185 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,01473962 0,02360133 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,01473962 0,02358084 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,01473962 0,02356039 ! neural crest cell development GO:0014032 19 17 0,000 0,01473962 0,02353997 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,01473962 0,02351959 ! negative regulation of cell development GO:0010721 18 17 0,000 0,01473962 0,02349924 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,01473962 0,02347893 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,01473962 0,02345866 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,01473962 0,02343842 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,01473962 0,02341821 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,01473962 0,02339804 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,01473962 0,02337791 ! pigmentation GO:0043473 17 17 0,000 0,01473962 0,0233578 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,01473962 0,02333774 ! adult locomotory behavior GO:0008344 17 17 0,000 0,01473962 0,02331771 ! embryonic organ development GO:0048568 17 17 0,000 0,01473962 0,02329771 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,01473962 0,02327774 ! liver development GO:0001889 17 17 0,000 0,01473962 0,02325781 ! gene silencing GO:0016458 17 17 0,000 0,01473962 0,02323792 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,01560099 0,02457489 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,01560099 0,02455391 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,01560099 0,02453296 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,01560099 0,02451204 ! meiosis I GO:0007127 18 18 0,000 0,01560099 0,02449116 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,01560099 0,02447032 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,01560099 0,02444951 ! membrane docking GO:0022406 18 18 0,000 0,01560099 0,02442874 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,01560099 0,024408 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,01560099 0,0243873 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,01560099 0,02436663 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,01560099 0,024346 ! hexose transport GO:0008645 18 18 0,000 0,01560099 0,0243254 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,01560099 0,02430484 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,01560099 0,02428431 ! striated muscle contraction GO:0006941 18 18 0,000 0,01560099 0,02426382 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,01560099 0,02424336 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,01560099 0,02422294 ! ceramide metabolic process GO:0006672 18 18 0,000 0,01560099 0,02420255 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,01560099 0,02418219 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,01560099 0,02416187 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,01560099 0,02414158 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,01560099 0,02412133 ! B cell differentiation GO:0030183 18 18 0,000 0,01560099 0,02410111 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,01560099 0,02408093 ! ensheathment of neurons GO:0007272 18 18 0,000 0,01560099 0,02406078 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,01560099 0,02404066 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,01560099 0,02402057 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,01560099 0,02400052 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,01560099 0,02398051 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,01560099 0,02396052 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,01646173 0,02526142 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,01646173 0,02524041 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,01646173 0,02521943 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,01646173 0,02519848 ! glial cell differentiation GO:0010001 19 19 0,000 0,01646173 0,02517757 ! regulation of pH GO:0006885 19 19 0,000 0,01646173 0,02515669 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,01646173 0,02513585 ! feeding behavior GO:0007631 19 19 0,000 0,01646173 0,02511504 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,01646173 0,02509427 ! peroxisome organization GO:0007031 19 19 0,000 0,01646173 0,02507353 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,01646173 0,02505282 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,01646173 0,02503215 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,01646173 0,02501152 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,01646173 0,02499091 ! metanephros development GO:0001656 19 19 0,000 0,01646173 0,02497035 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,01646173 0,02494981 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,01646173 0,02492931 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,01646173 0,02490884 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,01646173 0,02488841 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,01646173 0,02486801 ! peripheral nervous system development GO:0007422 19 19 0,000 0,01646173 0,02484764 ! regulation of protein stability GO:0031647 19 19 0,000 0,01646173 0,02482731 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,01646173 0,02480701 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,01646173 0,02478674 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,01646173 0,02476651 ! eye morphogenesis GO:0048592 19 19 0,000 0,01646173 0,0247463 ! regulation of cell shape GO:0008360 21 19 0,000 0,01646173 0,02472614 ! placenta development GO:0001890 19 19 0,000 0,01646173 0,024706 ! response to heat GO:0009408 19 19 0,000 0,01646173 0,0246859 ! vesicle localization GO:0051648 20 19 0,000 0,01646173 0,02466583 ! regulation of muscle development GO:0048634 21 20 0,000 0,01732184 0,02593351 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,01732184 0,02591246 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,01732184 0,02589145 ! negative regulation of binding GO:0051100 21 20 0,000 0,01732184 0,02587047 ! organic ether metabolic process GO:0018904 20 20 0,000 0,01732184 0,02584952 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,01732184 0,02582861 ! neural tube development GO:0021915 21 20 0,000 0,01732184 0,02580773 ! nucleus organization GO:0006997 20 20 0,000 0,01732184 0,02578688 ! phagocytosis GO:0006909 21 20 0,000 0,01732184 0,02576607 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,01732184 0,02574529 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,01732184 0,02572454 ! protein targeting to membrane GO:0006612 22 20 0,000 0,01732184 0,02570383 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,01732184 0,02568315 ! chromatin remodeling GO:0006338 20 20 0,000 0,01732184 0,0256625 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,01732184 0,02564189 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,01732184 0,02562131 ! lipid oxidation GO:0034440 20 20 0,000 0,01732184 0,02560077 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,01732184 0,02558025 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,01732184 0,02555977 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,01732184 0,02553932 ! RNA modification GO:0009451 20 20 0,000 0,01732184 0,02551891 ! single fertilization GO:0007338 21 20 0,000 0,01732184 0,02549853 ! regulation of B cell activation GO:0050864 20 20 0,000 0,01732184 0,02547818 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,01818133 0,02672104 ! mRNA catabolic process GO:0006402 21 21 0,000 0,01818133 0,02669975 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,01818133 0,02667849 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,01818133 0,02665727 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,01818133 0,02663608 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,01818133 0,02661492 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,01818133 0,0265938 ! Notch signaling pathway GO:0007219 22 21 0,000 0,01818133 0,02657271 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,01818133 0,02655165 ! ear morphogenesis GO:0042471 21 21 0,000 0,01818133 0,02653063 ! organic anion transport GO:0015711 21 21 0,000 0,01818133 0,02650964 ! cholesterol transport GO:0030301 21 21 0,000 0,01818133 0,02648869 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,01818133 0,02646776 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,01818133 0,02644687 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,01818133 0,02642602 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,01818133 0,02640519 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,01818133 0,0263844 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,01818133 0,02636364 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,01818133 0,02634291 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,01818133 0,02632222 ! regulation of proteolysis GO:0030162 21 21 0,000 0,01818133 0,02630156 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,01818133 0,02628093 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,01818133 0,02626033 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,01818133 0,02623977 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,01818133 0,02621924 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,01904019 0,02743633 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,01904019 0,02741489 ! sister chromatid segregation GO:0000819 22 22 0,000 0,01904019 0,02739349 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,01904019 0,02737212 ! regulation of ion transport GO:0043269 22 22 0,000 0,01904019 0,02735079 ! odontogenesis GO:0042476 22 22 0,000 0,01904019 0,02732949 ! cell junction organization GO:0034330 23 22 0,000 0,01904019 0,02730822 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,01904019 0,02728699 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,01904019 0,02726578 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,01904019 0,02724461 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,01904019 0,02722348 ! ovulation cycle process GO:0022602 22 22 0,000 0,01904019 0,02720238 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,01904019 0,0271813 ! cell chemotaxis GO:0060326 23 22 0,000 0,01904019 0,02716027 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,01904019 0,02713926 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,01904019 0,02711829 ! male sex differentiation GO:0046661 22 22 0,000 0,01904019 0,02709735 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,01904019 0,02707644 ! biopolymer methylation GO:0043414 22 22 0,000 0,01904019 0,02705556 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,01904019 0,02703472 ! detection of external stimulus GO:0009581 23 22 0,000 0,01904019 0,02701391 ! neuron migration GO:0001764 22 22 0,000 0,01904019 0,02699313 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,01904019 0,02697238 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,01904019 0,02695166 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,01904019 0,02693098 ! aerobic respiration GO:0009060 22 22 0,000 0,01904019 0,02691033 ! cytokine production GO:0001816 22 22 0,000 0,01904019 0,0268897 ! cytokinesis GO:0000910 23 22 0,000 0,01904019 0,02686911 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,01904019 0,02684856 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,01989842 0,0280373 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,01989842 0,02801588 ! viral infectious cycle GO:0019058 23 23 0,000 0,01989842 0,02799449 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,01989842 0,02797314 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,01989842 0,02795182 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,01989842 0,02793053 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,01989842 0,02790927 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,01989842 0,02788805 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,01989842 0,02786686 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,01989842 0,0278457 ! endocrine system development GO:0035270 23 23 0,000 0,01989842 0,02782457 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,01989842 0,02780348 ! positive regulation of growth GO:0045927 23 23 0,000 0,01989842 0,02778241 ! female gonad development GO:0008585 23 23 0,000 0,01989842 0,02776138 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,01989842 0,02774038 ! lipid homeostasis GO:0055088 23 23 0,000 0,01989842 0,02771942 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,01989842 0,02769848 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,01989842 0,02767757 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,01989842 0,0276567 ! cell projection assembly GO:0030031 25 23 0,000 0,01989842 0,02763586 ! mitochondrial transport GO:0006839 24 24 0,000 0,02075603 0,02880524 ! regulation of action potential GO:0001508 24 24 0,000 0,02075603 0,02878356 ! gliogenesis GO:0042063 24 24 0,000 0,02075603 0,02876192 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,02075603 0,02874031 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,02075603 0,02871874 ! glucose homeostasis GO:0042593 24 24 0,000 0,02075603 0,02869719 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,02075603 0,02867568 ! T cell differentiation GO:0030217 24 24 0,000 0,02075603 0,0286542 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,02075603 0,02863275 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,02075603 0,02861134 ! ovulation cycle GO:0042698 24 24 0,000 0,02075603 0,02858995 ! fertilization GO:0009566 25 24 0,000 0,02075603 0,0285686 ! maintenance of protein location GO:0045185 25 24 0,000 0,02075603 0,02854728 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,02075603 0,02852599 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,02075603 0,02850474 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,02075603 0,02848351 ! glucan metabolic process GO:0044042 25 24 0,000 0,02075603 0,02846232 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,02161301 0,02961544 ! negative regulation of secretion GO:0051048 26 25 0,000 0,02161301 0,02959344 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,02161301 0,02957147 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,02161301 0,02954953 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,02161301 0,02952763 ! endosome transport GO:0016197 25 25 0,000 0,02161301 0,02950576 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,02161301 0,02948392 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,02161301 0,02946211 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,02161301 0,02944033 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,02161301 0,02941859 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,02161301 0,02939688 ! excretion GO:0007588 25 25 0,000 0,02161301 0,0293752 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,02161301 0,02935355 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,02161301 0,02933194 ! gastrulation GO:0007369 25 25 0,000 0,02161301 0,02931035 ! heart morphogenesis GO:0003007 25 25 0,000 0,02161301 0,0292888 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,02161301 0,02926728 ! regulation of endocytosis GO:0030100 25 25 0,000 0,02161301 0,02924579 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,02161301 0,02922434 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,02161301 0,02920291 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,02161301 0,02918152 ! positive regulation of binding GO:0051099 27 26 0,000 0,02246936 0,03031555 ! positive regulation of defense response GO:0031349 26 26 0,000 0,02246936 0,03029337 ! glycolysis GO:0006096 26 26 0,000 0,02246936 0,03027123 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,02246936 0,03024911 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,02246936 0,03022703 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,02246936 0,03020499 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,02246936 0,03018297 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,02246936 0,03016099 ! cellular defense response GO:0006968 26 26 0,000 0,02246936 0,03013904 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,02246936 0,03011712 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,02246936 0,03009523 ! double-strand break repair GO:0006302 27 26 0,000 0,02246936 0,03007337 ! regulation of protein secretion GO:0050708 26 26 0,000 0,02246936 0,03005155 ! germ cell development GO:0007281 27 26 0,000 0,02246936 0,03002976 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,02246936 0,030008 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,02246936 0,02998627 ! maintenance of location in cell GO:0051651 27 26 0,000 0,02246936 0,02996457 ! synapse organization GO:0050808 26 26 0,000 0,02246936 0,0299429 ! chloride transport GO:0006821 27 27 0,000 0,02332509 0,0310608 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,02332509 0,03103838 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,02332509 0,03101598 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,02332509 0,03099362 ! learning or memory GO:0007611 28 27 0,000 0,02332509 0,03097129 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,02332509 0,03094899 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,02332509 0,03092673 ! peptide metabolic process GO:0006518 29 27 0,000 0,02332509 0,03090449 ! activation of caspase activity GO:0006919 27 27 0,000 0,02332509 0,03088229 ! mesenchymal cell development GO:0014031 29 27 0,000 0,02332509 0,03086012 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,02332509 0,03083798 ! defense response to bacterium GO:0042742 27 27 0,000 0,02332509 0,03081588 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,02332509 0,0307938 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,02332509 0,03077176 ! cell growth GO:0016049 27 27 0,000 0,02332509 0,03074975 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,0241802 0,03185426 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,0241802 0,03183151 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,0241802 0,03180879 ! carbohydrate transport GO:0008643 28 28 0,000 0,0241802 0,0317861 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,0241802 0,03176344 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,0241802 0,03174082 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,0241802 0,03171823 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,0241802 0,03169567 ! histone modification GO:0016570 28 28 0,000 0,0241802 0,03167314 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,0241802 0,03165065 ! developmental growth GO:0048589 28 28 0,000 0,0241802 0,03162818 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,0241802 0,03160575 ! cartilage development GO:0051216 29 28 0,000 0,0241802 0,03158335 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,02503469 0,03267629 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,02503469 0,03265317 ! viral reproductive process GO:0022415 29 29 0,000 0,02503469 0,03263007 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,02503469 0,03260701 ! leukocyte migration GO:0050900 30 29 0,000 0,02503469 0,03258399 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,02503469 0,03256099 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,02503469 0,03253803 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,02503469 0,0325151 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,02503469 0,0324922 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,02503469 0,03246934 ! tRNA processing GO:0008033 29 29 0,000 0,02503469 0,0324465 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,02503469 0,0324237 ! covalent chromatin modification GO:0016569 29 29 0,000 0,02503469 0,03240093 ! adult behavior GO:0030534 30 29 0,000 0,02503469 0,03237819 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,02503469 0,03235549 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,02503469 0,03233281 ! response to UV GO:0009411 29 29 0,000 0,02503469 0,03231017 ! transition metal ion transport GO:0000041 31 30 0,000 0,02588854 0,0333888 ! RNA catabolic process GO:0006401 30 30 0,000 0,02588854 0,03336545 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,02588854 0,03334213 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,02588854 0,03331885 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,02588854 0,0332956 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,02588854 0,03327238 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,02588854 0,03324919 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,02588854 0,03322604 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,02588854 0,03320291 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,02588854 0,03317982 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,02588854 0,03315677 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,02588854 0,03313374 ! response to temperature stimulus GO:0009266 30 30 0,000 0,02588854 0,03311075 ! regulation of ossification GO:0030278 30 30 0,000 0,02588854 0,03308779 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,02588854 0,03306486 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,02588854 0,03304196 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,02588854 0,03301909 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,02588854 0,03299626 ! vesicle organization GO:0016050 30 30 0,000 0,02588854 0,03297345 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,02588854 0,03295068 ! establishment of organelle localization GO:0051656 31 30 0,000 0,02588854 0,03292794 ! regulation of translational initiation GO:0006446 31 31 0,000 0,02674178 0,03398973 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,02674178 0,0339663 ! membrane fusion GO:0006944 31 31 0,000 0,02674178 0,03394291 ! B cell activation GO:0042113 31 31 0,000 0,02674178 0,03391955 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,02674178 0,03389622 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,02674178 0,03387292 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,02674178 0,03384966 ! ion transmembrane transport GO:0034220 31 31 0,000 0,02674178 0,03382643 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,02674178 0,03380323 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,02674178 0,03378006 ! digestion GO:0007586 31 31 0,000 0,02674178 0,03375692 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,02674178 0,03373381 ! regulation of DNA replication GO:0006275 32 31 0,000 0,02674178 0,03371074 ! regulation of heart contraction GO:0008016 31 31 0,000 0,02674178 0,0336877 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,02674178 0,03366469 ! camera-type eye development GO:0043010 31 31 0,000 0,02674178 0,03364171 ! extracellular matrix organization GO:0030198 31 31 0,000 0,02674178 0,03361876 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,02674178 0,03359584 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,02674178 0,03357296 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,02674178 0,0335501 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,02674178 0,03352728 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,02674178 0,03350449 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,02759439 0,03454923 ! cell redox homeostasis GO:0045454 32 32 0,000 0,02759439 0,03452578 ! muscle fiber development GO:0048747 32 32 0,000 0,02759439 0,03450235 ! glucose catabolic process GO:0006007 32 32 0,000 0,02759439 0,03447896 ! lipid modification GO:0030258 32 32 0,000 0,02759439 0,0344556 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,02759439 0,03443227 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,02759439 0,03440898 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,02759439 0,03438571 ! cell maturation GO:0048469 32 32 0,000 0,02759439 0,03436248 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,02759439 0,03433928 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,02759439 0,03431611 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,02759439 0,03429297 ! kidney development GO:0001822 32 32 0,000 0,02759439 0,03426986 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,02759439 0,03424678 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,02759439 0,03422373 ! maintenance of location GO:0051235 33 32 0,000 0,02759439 0,03420072 ! negative regulation of cell size GO:0045792 33 33 0,000 0,02844639 0,03523299 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,02844639 0,03520933 ! amino acid transport GO:0006865 33 33 0,000 0,02844639 0,0351857 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,02844639 0,0351621 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,02844639 0,03513853 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,02844639 0,035115 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,02844639 0,03509149 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,02844639 0,03506802 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,02844639 0,03504458 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,02844639 0,03502117 ! regulation of actin filament length GO:0030832 34 34 0,000 0,02929775 0,03604523 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,02929775 0,03602119 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,02929775 0,03599717 ! response to metal ion GO:0010038 34 34 0,000 0,02929775 0,03597319 ! ear development GO:0043583 34 34 0,000 0,02929775 0,03594924 ! muscle cell differentiation GO:0042692 35 34 0,000 0,02929775 0,03592532 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,02929775 0,03590144 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,02929775 0,03587758 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,02929775 0,03585376 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,02929775 0,03582997 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,02929775 0,03580621 ! secondary metabolic process GO:0019748 34 34 0,000 0,02929775 0,03578248 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,02929775 0,03575878 ! viral reproduction GO:0016032 34 34 0,000 0,02929775 0,03573512 ! detection of stimulus GO:0051606 36 34 0,000 0,02929775 0,03571148 ! acute inflammatory response GO:0002526 35 35 0,000 0,0301485 0,03672418 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,0301485 0,03669993 ! regulation of cellular component size GO:0032535 35 35 0,000 0,0301485 0,0366757 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,0301485 0,03665151 ! mesoderm development GO:0007498 35 35 0,000 0,0301485 0,03662735 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,0301485 0,03660322 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,0301485 0,03657912 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,0301485 0,03655506 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,0301485 0,03653102 ! inorganic anion transport GO:0015698 35 35 0,000 0,0301485 0,03650702 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,0301485 0,03648305 ! regulation of immune effector process GO:0002697 35 35 0,000 0,0301485 0,03645911 ! hydrogen transport GO:0006818 36 36 0,000 0,03099863 0,0374626 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,03099863 0,03743805 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,03099863 0,03741354 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,03099863 0,03738905 ! regulation of mitosis GO:0007088 37 36 0,000 0,03099863 0,0373646 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,03099863 0,03734018 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,03099863 0,03731579 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,03099863 0,03729143 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,03099863 0,0372671 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,03099863 0,03724281 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,03099863 0,03721855 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,03099863 0,03719432 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,03099863 0,03717012 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,03099863 0,03714595 ! gonad development GO:0008406 36 36 0,000 0,03099863 0,03712181 ! regulation of lipase activity GO:0060191 36 36 0,000 0,03099863 0,03709771 ! activation of immune response GO:0002253 36 36 0,000 0,03099863 0,03707363 ! coagulation GO:0050817 39 36 0,000 0,03099863 0,03704959 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,03184813 0,03804025 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,03184813 0,03801561 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,03184813 0,03799101 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,03184813 0,03796643 ! response to drug GO:0042493 37 37 0,000 0,03184813 0,03794189 ! lung development GO:0030324 38 37 0,000 0,03184813 0,03791738 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,03184813 0,0378929 ! eye development GO:0001654 37 37 0,000 0,03184813 0,03786846 ! negative regulation of growth GO:0045926 37 37 0,000 0,03184813 0,03784404 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,03184813 0,03781966 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,03184813 0,0377953 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,03184813 0,03777098 ! adaptive immune response GO:0002250 37 37 0,000 0,03184813 0,03774669 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,03269701 0,03872789 ! neurotransmitter transport GO:0006836 40 38 0,000 0,03269701 0,03870302 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,03269701 0,03867818 ! exocytosis GO:0006887 40 38 0,000 0,03269701 0,03865337 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,03269701 0,03862859 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,03269701 0,03860384 ! chromosome segregation GO:0007059 38 38 0,000 0,03269701 0,03857913 ! urogenital system development GO:0001655 38 38 0,000 0,03269701 0,03855445 ! hexose catabolic process GO:0019320 38 38 0,000 0,03269701 0,03852979 ! RNA elongation GO:0006354 38 38 0,000 0,03269701 0,03850517 ! meiotic cell cycle GO:0051321 38 38 0,000 0,03269701 0,03848059 ! axon guidance GO:0007411 39 38 0,000 0,03269701 0,03845603 ! regulation of neurological system process GO:0031644 38 38 0,000 0,03269701 0,0384315 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,03269701 0,03840701 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,03269701 0,03838255 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,03354528 0,03935324 ! hemostasis GO:0007599 42 39 0,000 0,03354528 0,03932821 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,03354528 0,03930321 ! activation of MAPK activity GO:0000187 39 39 0,000 0,03354528 0,03927824 ! respiratory tube development GO:0030323 40 39 0,000 0,03354528 0,0392533 ! response to unfolded protein GO:0006986 39 39 0,000 0,03354528 0,03922839 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,03354528 0,03920352 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,03354528 0,03917867 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,03354528 0,03915386 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,03354528 0,03912908 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,03354528 0,03910433 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,03354528 0,03907961 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,03354528 0,03905493 ! respiratory system development GO:0060541 40 39 0,000 0,03354528 0,03903027 ! developmental maturation GO:0021700 39 39 0,000 0,03354528 0,03900565 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,03354528 0,03898105 ! limb development GO:0060173 39 39 0,000 0,03354528 0,03895649 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,03354528 0,03893196 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,03354528 0,03890746 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,03439292 0,03986551 ! DNA catabolic process GO:0006308 41 40 0,000 0,03439292 0,03984045 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,03439292 0,03981542 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,03439292 0,03979043 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,03439292 0,03976547 ! organelle localization GO:0051640 41 40 0,000 0,03439292 0,03974054 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,03523995 0,04069375 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,03523995 0,04066826 ! amine catabolic process GO:0009310 42 41 0,000 0,03523995 0,04064282 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,03523995 0,0406174 ! regulation of caspase activity GO:0043281 41 41 0,000 0,03523995 0,04059201 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,03523995 0,04056666 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,03523995 0,04054134 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,03523995 0,04051604 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,03608635 0,04146331 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,03608635 0,04143747 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,03608635 0,04141167 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,03608635 0,0413859 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,03608635 0,04136016 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,03608635 0,04133446 ! protein ubiquitination GO:0016567 43 42 0,000 0,03608635 0,04130878 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,03608635 0,04128314 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,03608635 0,04125753 ! forebrain development GO:0030900 43 42 0,000 0,03608635 0,04123195 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,03608635 0,04120641 ! reproductive structure development GO:0048608 43 43 0,000 0,03693214 0,04214608 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,03693214 0,04212 ! mitochondrion organization GO:0007005 44 43 0,000 0,03693214 0,04209396 ! alcohol catabolic process GO:0046164 43 43 0,000 0,03693214 0,04206794 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,03693214 0,04204196 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,03693214 0,042016 ! humoral immune response GO:0006959 44 44 0,000 0,0377773 0,042951 ! mRNA transport GO:0051028 44 44 0,000 0,0377773 0,04292452 ! protein import into nucleus GO:0006606 44 44 0,000 0,0377773 0,04289807 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,0377773 0,04287166 ! vitamin metabolic process GO:0006766 44 44 0,000 0,0377773 0,04284527 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,0377773 0,04281892 ! amine biosynthetic process GO:0009309 46 45 0,000 0,03862185 0,04374928 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,03862185 0,0437224 ! regulation of DNA binding GO:0051101 47 45 0,000 0,03862185 0,04369556 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,03862185 0,04366876 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,03862185 0,04364198 ! nuclear import GO:0051170 45 45 0,000 0,03862185 0,04361524 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,03862185 0,04358853 ! protein processing GO:0016485 45 45 0,000 0,03862185 0,04356186 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,03946578 0,04448651 ! tube morphogenesis GO:0035239 47 46 0,000 0,03946578 0,04445931 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,03946578 0,04443215 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,03946578 0,04440503 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,03946578 0,04437794 ! regulation of membrane potential GO:0042391 46 46 0,000 0,03946578 0,04435088 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,0403091 0,04527097 ! regulation of blood pressure GO:0008217 48 47 0,000 0,0403091 0,0452434 ! sex differentiation GO:0007548 47 47 0,000 0,0403091 0,04521586 ! amine transport GO:0015837 47 47 0,000 0,0403091 0,04518836 ! rhythmic process GO:0048511 47 47 0,000 0,0403091 0,04516089 ! regulation of catabolic process GO:0009894 48 47 0,000 0,0403091 0,04513345 ! calcium ion transport GO:0006816 48 48 0,000 0,04115179 0,04604903 ! actin filament organization GO:0007015 50 48 0,000 0,04115179 0,04602109 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,04115179 0,04599318 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,04115179 0,04596531 ! protein localization in nucleus GO:0034504 48 48 0,000 0,04115179 0,04593746 ! DNA recombination GO:0006310 48 48 0,000 0,04115179 0,04590966 ! leukocyte differentiation GO:0002521 50 49 0,000 0,04199387 0,04682075 ! ossification GO:0001503 50 49 0,000 0,04199387 0,04679245 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,04199387 0,04676417 ! cell cycle arrest GO:0007050 49 49 0,000 0,04199387 0,04673593 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,04199387 0,04670773 ! divalent metal ion transport GO:0070838 49 49 0,000 0,04199387 0,04667956 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,04199387 0,04665142 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,04199387 0,04662332 ! response to bacterium GO:0009617 50 49 0,000 0,04199387 0,04659525 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,04199387 0,04656721 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,04199387 0,04653921 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,04199387 0,04651124 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,04283534 0,04741473 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,04283534 0,04738627 ! negative regulation of transport GO:0051051 51 50 0,000 0,04283534 0,04735784 ! chromatin assembly GO:0031497 50 50 0,000 0,04283534 0,04732945 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 0,000 0,04283534 0,04730109 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,04283534 0,04727277 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,04283534 0,04724448 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,04283534 0,04721622 ! transcription initiation GO:0006352 50 50 0,000 0,04283534 0,047188 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,04283534 0,04715981 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,04283534 0,04713166 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,04367618 0,04802817 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,04367618 0,04799953 ! positive regulation of immune response GO:0050778 51 51 0,000 0,04367618 0,04797092 ! rRNA metabolic process GO:0016072 51 51 0,000 0,04367618 0,04794235 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,04367618 0,04791381 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,04367618 0,04788531 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,04367618 0,04785684 ! protein maturation GO:0051604 51 51 0,000 0,04367618 0,04782841 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,04451642 0,04871957 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,04451642 0,04869065 ! cell fate commitment GO:0045165 52 52 0,000 0,04451642 0,04866178 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,04451642 0,04863293 ! response to light stimulus GO:0009416 53 52 0,000 0,04451642 0,04860412 ! sodium ion transport GO:0006814 53 53 0,000 0,04535603 0,04949151 ! tRNA metabolic process GO:0006399 53 53 0,000 0,04535603 0,04946223 ! response to hypoxia GO:0001666 53 53 0,000 0,04535603 0,04943298 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,04535603 0,04940376 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,04535603 0,04937458 ! regulation of T cell activation GO:0050863 53 53 0,000 0,04535603 0,04934543 ! regulation of protein transport GO:0051223 53 53 0,000 0,04535603 0,04931632 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,04619503 0,05019897 ! response to oxygen levels GO:0070482 55 54 0,000 0,04619503 0,05016938 ! response to virus GO:0009615 54 54 0,000 0,04619503 0,05013984 ! hormone metabolic process GO:0042445 55 54 0,000 0,04619503 0,05011033 ! sulfur metabolic process GO:0006790 55 54 0,000 0,04619503 0,05008085 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,04619503 0,05005141 ! nucleosome organization GO:0034728 55 55 0,000 0,04703342 0,05092984 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,04703342 0,05089994 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,04703342 0,05087007 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,04703342 0,05084023 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,04787119 0,05171548 ! reproductive developmental process GO:0003006 56 56 0,000 0,04787119 0,05168518 ! extracellular structure organization GO:0043062 56 56 0,000 0,04787119 0,05165492 ! regulation of nervous system development GO:0051960 57 56 0,000 0,04787119 0,0516247 ! regulation of binding GO:0051098 60 57 0,000 0,04870835 0,05249678 ! ATP metabolic process GO:0046034 57 57 0,000 0,04870835 0,0524661 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,04870835 0,05243545 ! regulation of protein localization GO:0032880 58 57 0,000 0,04870835 0,05240484 ! innate immune response GO:0045087 58 58 0,000 0,0495449 0,05327377 ! dephosphorylation GO:0016311 60 59 0,000 0,05038083 0,05414103 ! carboxylic acid transport GO:0046942 59 59 0,000 0,05038083 0,05410948 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,05038083 0,05407797 ! regulation of cell development GO:0060284 60 59 0,000 0,05038083 0,05404649 ! sterol metabolic process GO:0016125 59 59 0,000 0,05038083 0,05401505 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,05038083 0,05398364 ! protein localization in organelle GO:0033365 59 59 0,000 0,05038083 0,05395228 ! immune effector process GO:0002252 59 59 0,000 0,05038083 0,05392095 ! potassium ion transport GO:0006813 60 60 0,000 0,05121615 0,05478315 ! protein polymerization GO:0051258 65 60 0,000 0,05121615 0,05475137 ! cellular respiration GO:0045333 62 61 0,000 0,05205086 0,05561144 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,05205086 0,05557922 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,05205086 0,05554703 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,05205086 0,05551489 ! lipid transport GO:0006869 62 62 0,000 0,05288495 0,05637187 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,05288495 0,05633929 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,05288495 0,05630674 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,05288495 0,05627423 ! protein import GO:0017038 62 62 0,000 0,05288495 0,05624176 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,05288495 0,05620932 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,05288495 0,05617693 ! regulation of secretion GO:0051046 65 63 0,000 0,05371844 0,05702942 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,05371844 0,05699659 ! glucose metabolic process GO:0006006 63 63 0,000 0,05371844 0,0569638 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,05371844 0,05693104 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,05371844 0,05689832 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,05455131 0,05774731 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,05455131 0,05771416 ! angiogenesis GO:0001525 65 64 0,000 0,05455131 0,05768104 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,05455131 0,05764797 ! anion transport GO:0006820 65 65 0,000 0,05538357 0,05849394 ! regulation of hormone levels GO:0010817 66 65 0,000 0,05538357 0,05846043 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,05621522 0,05930432 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,05621522 0,05927039 ! DNA packaging GO:0006323 66 66 0,000 0,05621522 0,05923651 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,05621522 0,05920266 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,05621522 0,05916885 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,05704626 0,06000928 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,05704626 0,05997505 ! muscle contraction GO:0006936 67 67 0,000 0,05704626 0,05994085 ! striated muscle tissue development GO:0014706 69 67 0,000 0,05704626 0,0599067 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,05704626 0,05987258 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,05704626 0,05983851 ! response to radiation GO:0009314 70 68 0,000 0,05787669 0,06067505 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,05787669 0,06064056 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,05787669 0,0606061 ! regulation of cell size GO:0008361 68 68 0,000 0,05787669 0,06057169 ! sensory perception of sound GO:0007605 71 69 0,000 0,05870651 0,06140528 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,05870651 0,06137045 ! response to nutrient levels GO:0031667 69 69 0,000 0,05870651 0,06133566 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,05870651 0,06130091 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,05870651 0,06126619 ! positive regulation of transport GO:0051050 71 70 0,000 0,05953572 0,0620964 ! cell part morphogenesis GO:0032990 75 70 0,000 0,05953572 0,06206128 ! wound healing GO:0042060 74 70 0,000 0,05953572 0,06202619 ! growth GO:0040007 70 70 0,000 0,05953572 0,06199115 ! muscle tissue development GO:0060537 72 70 0,000 0,05953572 0,06195615 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,05953572 0,06192118 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,06036433 0,06274758 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,06036433 0,0627122 ! regulation of cell migration GO:0030334 71 71 0,000 0,06036433 0,06267687 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,06036433 0,06264158 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 0,000 0,06036433 0,06260633 ! secretion by cell GO:0032940 75 72 0,000 0,06119232 0,06342938 ! muscle system process GO:0003012 72 72 0,000 0,06119232 0,06339373 ! sensory organ development GO:0007423 72 72 0,000 0,06119232 0,06335812 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,06119232 0,06332254 ! regulation of cytokine production GO:0001817 72 72 0,000 0,06119232 0,06328701 ! electron transport chain GO:0022900 75 74 0,000 0,06284648 0,06496134 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,06284648 0,06492493 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,06367266 0,06574157 ! response to oxidative stress GO:0006979 76 75 0,000 0,06367266 0,06570476 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,06367266 0,06566799 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,06449822 0,06648223 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,06532318 0,06729492 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,06532318 0,06725733 ! microtubule-based movement GO:0007018 82 78 0,000 0,06614753 0,06806806 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,06614753 0,06803008 ! metal ion homeostasis GO:0055065 78 78 0,000 0,06614753 0,06799213 ! regulation of immune response GO:0050776 78 78 0,000 0,06614753 0,06795423 ! regulation of locomotion GO:0040012 79 79 0,000 0,06697127 0,06876215 ! regulation of cell motion GO:0051270 79 79 0,000 0,06697127 0,06872386 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,06779441 0,06952983 ! neuron projection development GO:0031175 85 80 0,000 0,06779441 0,06949116 ! MAPKKK cascade GO:0000165 82 81 0,000 0,06861695 0,07029518 ! tube development GO:0035295 83 81 0,000 0,06861695 0,07025613 ! lymphocyte activation GO:0046649 82 81 0,000 0,06861695 0,07021712 ! lipid catabolic process GO:0016042 82 81 0,000 0,06861695 0,07017815 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,0702602 0,07181894 ! ncRNA processing GO:0034470 83 83 0,000 0,0702602 0,07177913 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,0702602 0,07173936 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,07108092 0,07253718 ! regulation of cellular localization GO:0060341 86 85 0,000 0,07190104 0,07333349 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,07190104 0,07329293 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,07190104 0,07325241 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,07190104 0,07321194 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,07272055 0,07400551 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,07272055 0,07396467 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,07272055 0,07392387 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,07272055 0,07388312 ! heart development GO:0007507 90 87 0,000 0,07353946 0,07467396 ! male gamete generation GO:0048232 90 88 0,000 0,07435777 0,07546331 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,07435777 0,07542178 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,07435777 0,07538029 ! chemotaxis GO:0006935 90 89 0,000 0,07517548 0,07616735 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,07517548 0,0761255 ! brain development GO:0007420 91 90 0,000 0,07599258 0,07691067 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,07680908 0,07769437 ! visual perception GO:0007601 93 92 0,000 0,07762498 0,0784766 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,07762498 0,07843357 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,07762498 0,0783906 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,07762498 0,07834767 ! tissue morphogenesis GO:0048729 94 93 0,000 0,07844028 0,07912722 ! regulation of response to stress GO:0080134 97 94 0,000 0,07925498 0,07990532 ! blood vessel development GO:0001568 95 94 0,000 0,07925498 0,07986163 ! pattern specification process GO:0007389 96 94 0,000 0,07925498 0,07981799 ! epidermis development GO:0008544 94 94 0,000 0,07925498 0,0797744 ! cofactor metabolic process GO:0051186 95 94 0,000 0,07925498 0,07973085 ! regulation of cell growth GO:0001558 97 96 0,000 0,08088257 0,08132383 ! vasculature development GO:0001944 97 96 0,000 0,08088257 0,08127949 ! endocytosis GO:0006897 99 98 0,000 0,08250777 0,08286748 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,08250777 0,08282234 ! blood circulation GO:0008015 99 98 0,000 0,08250777 0,08277726 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,08250777 0,08273222 ! ectoderm development GO:0007398 99 99 0,000 0,08331947 0,0835007 ! muscle organ development GO:0007517 102 100 0,000 0,08413058 0,08426774 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,08413058 0,08422197 ! response to other organism GO:0051707 101 100 0,000 0,08413058 0,08417625 ! hemopoiesis GO:0030097 104 100 0,000 0,08413058 0,08413058