pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/3741-4-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! anagen GO:0042640 7 5 1,000 2,193E-05 0,05205149 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 2,193E-05 0,02602574 ! regulation of potassium ion transport GO:0043266 9 5 1,000 2,193E-05 0,0173505 ! definitive hemopoiesis GO:0060216 5 5 1,000 2,193E-05 0,01301287 ! negative regulation of myoblast differentiation GO:0045662 5 5 1,000 2,193E-05 0,0104103 ! regulation of keratinocyte differentiation GO:0045616 7 5 1,000 2,193E-05 8,675E-03 ! ectodermal gut morphogenesis GO:0048567 6 5 1,000 2,193E-05 7,436E-03 GO:0007439|ectodermal gut development, ! embryonic camera-type eye development GO:0031076 11 6 1,000 3,287E-05 9,75E-03 GO:0048596|embryonic camera-type eye morphogenesis, ! hair follicle maturation GO:0048820 8 6 1,000 3,287E-05 8,667E-03 ! positive regulation of Rho GTPase activity GO:0032321 12 6 1,000 3,287E-05 7,8E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 4,598E-05 9,918E-03 ! enucleate erythrocyte differentiation GO:0043353 10 7 1,000 4,598E-05 9,092E-03 ! regulation of myoblast differentiation GO:0045661 9 7 1,000 4,598E-05 8,393E-03 ! positive regulation of epidermis development GO:0045684 11 7 1,000 4,598E-05 7,793E-03 ! regulation of epidermal cell differentiation GO:0045604 10 7 1,000 4,598E-05 7,274E-03 ! keratinocyte proliferation GO:0043616 15 8 1,000 6,124E-05 9,083E-03 ! regulation of focal adhesion formation GO:0051893 17 8 1,000 6,124E-05 8,549E-03 ! trophectodermal cell differentiation GO:0001829 10 8 1,000 6,124E-05 8,074E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 2,000 6,895E-05 8,612E-03 ! negative regulation of muscle cell differentiation GO:0051148 10 9 1,000 7,867E-05 9,334E-03 ! endoderm development GO:0007492 12 9 1,000 7,867E-05 8,89E-03 ! embryonic eye morphogenesis GO:0048048 15 9 1,000 7,867E-05 8,486E-03 ! hair follicle morphogenesis GO:0031069 17 10 1,000 9,824E-05 0,0101363 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 1,000 9,824E-05 9,714E-03 ! regulation of stress fiber formation GO:0051492 24 10 1,000 9,824E-05 9,325E-03 ! protein homotetramerization GO:0051289 20 10 1,000 9,824E-05 8,967E-03 ! positive regulation of Ras GTPase activity GO:0032320 24 10 1,000 9,824E-05 8,635E-03 ! blastocyst formation GO:0001825 14 10 1,000 9,824E-05 8,326E-03 ! regulation of phosphatase activity GO:0010921 23 11 1,000 1,2E-04 9,816E-03 ! digestive tract morphogenesis GO:0048546 16 11 1,000 1,2E-04 9,489E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of actin filament bundle formation GO:0032231 25 11 1,000 1,2E-04 9,183E-03 ! lung development GO:0030324 112 66 2,000 1,329E-04 9,857E-03 ! positive regulation of GTPase activity GO:0043547 29 12 1,000 1,438E-04 0,01034212 ! focal adhesion formation GO:0048041 28 12 1,000 1,438E-04 0,01003794 ! regulation of Rho GTPase activity GO:0032319 22 12 1,000 1,438E-04 9,751E-03 ! histone deacetylation GO:0016575 14 12 1,000 1,438E-04 9,48E-03 ! embryonic placenta development GO:0001892 15 12 1,000 1,438E-04 9,224E-03 ! respiratory tube development GO:0030323 117 69 2,000 1,517E-04 9,475E-03 ! regulation of skeletal muscle fiber development GO:0048742 22 13 1,000 1,698E-04 0,01033242 ! regulation of epidermis development GO:0045682 21 13 1,000 1,698E-04 0,01007411 ! respiratory system development GO:0060541 123 72 2,000 1,722E-04 9,966E-03 ! regulation of protein ubiquitination GO:0031396 20 14 1,000 1,979E-04 0,01118296 ! epidermis morphogenesis GO:0048730 31 14 1,000 1,979E-04 0,01092289 ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,979E-04 0,01067464 ! epithelial to mesenchymal transition GO:0001837 24 14 1,000 1,979E-04 0,01043742 ! microspike assembly GO:0030035 25 14 1,000 1,979E-04 0,01021052 ! regulation of skeletal muscle tissue development GO:0048641 24 15 1,000 2,282E-04 0,01151989 ! skin development GO:0043588 28 15 1,000 2,282E-04 0,0112799 ! embryonic hindlimb morphogenesis GO:0035116 28 15 1,000 2,282E-04 0,01104969 ! release of cytochrome c from mitochondria GO:0001836 29 15 1,000 2,282E-04 0,0108287 ! positive regulation of cell growth GO:0030307 22 16 1,000 2,605E-04 0,01212162 ! protein amino acid deacetylation GO:0006476 23 17 1,000 2,95E-04 0,01346101 ! negative regulation of ion transport GO:0043271 19 17 1,000 2,95E-04 0,01320703 ! regulation of muscle cell differentiation GO:0051147 26 17 1,000 2,95E-04 0,01296246 ! negative regulation of peptidase activity GO:0010466 25 17 1,000 2,95E-04 0,01272678 ! cell-substrate junction assembly GO:0007044 45 18 1,000 3,315E-04 0,01404877 ! cellular response to unfolded protein GO:0034620 24 18 1,000 3,315E-04 0,0138023 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 38 18 1,000 3,315E-04 0,01356433 ! gut development GO:0048565 29 18 1,000 3,315E-04 0,01333442 ! positive regulation of cell size GO:0045793 26 19 1,000 3,702E-04 0,01464105 ! determination of left/right symmetry GO:0007368 24 19 1,000 3,702E-04 0,01440104 ! determination of bilateral symmetry GO:0009855 26 20 1,000 4,109E-04 0,01572831 GO:0009799|determination of symmetry, ! hindlimb morphogenesis GO:0035137 35 20 1,000 4,109E-04 0,01547866 ! negative regulation of neuron differentiation GO:0045665 33 20 1,000 4,109E-04 0,0152368 ! embryonic organ morphogenesis GO:0048562 26 20 1,000 4,109E-04 0,01500239 ! negative regulation of translation GO:0017148 28 20 1,000 4,109E-04 0,01477508 ! apoptotic mitochondrial changes GO:0008637 42 21 1,000 4,538E-04 0,01607154 ! molting cycle process GO:0022404 43 22 1,000 4,987E-04 0,01740238 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein tetramerization GO:0051262 43 22 1,000 4,987E-04 0,01715018 ! blastocyst development GO:0001824 41 23 1,000 5,457E-04 0,01849784 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 1,000 5,947E-04 0,0198766 ! response to endoplasmic reticulum stress GO:0034976 32 24 1,000 5,947E-04 0,01960053 ! neuron fate commitment GO:0048663 38 25 1,000 6,458E-04 0,02099339 ! regulation of cell-matrix adhesion GO:0001952 57 25 1,000 6,458E-04 0,02070969 GO:0010810|regulation of cell-substrate adhesion, ! camera-type eye morphogenesis GO:0048593 43 25 1,000 6,458E-04 0,02043357 ! liver development GO:0001889 44 25 1,000 6,458E-04 0,0201647 ! ER-nuclear signaling pathway GO:0006984 33 26 1,000 6,99E-04 0,02154119 ! fat cell differentiation GO:0045444 41 27 1,000 7,542E-04 0,02294471 ! negative regulation of protein modification process GO:0031400 56 28 1,000 8,114E-04 0,02437405 ! positive regulation of cell adhesion GO:0045785 54 29 1,000 8,707E-04 0,02582807 ! cell junction assembly GO:0034329 65 30 1,000 9,321E-04 0,02730569 ! regulation of striated muscle tissue development GO:0016202 51 32 1,000 1,061E-03 0,0306975 ! placenta development GO:0001890 45 32 1,000 1,061E-03 0,03032765 ! regulation of muscle development GO:0048634 52 33 1,000 1,128E-03 0,03187006 ! glial cell differentiation GO:0010001 65 33 1,000 1,128E-03 0,03149512 ! erythrocyte differentiation GO:0030218 50 33 1,000 1,128E-03 0,0311289 ! cell fate specification GO:0001708 49 34 1,000 1,198E-03 0,03266367 ! cell junction organization GO:0034330 72 35 1,000 1,269E-03 0,03421755 ! negative regulation of hydrolase activity GO:0051346 56 35 1,000 1,269E-03 0,03383308 ! embryonic organ development GO:0048568 53 35 1,000 1,269E-03 0,03345716 ! protein homooligomerization GO:0051260 59 35 1,000 1,269E-03 0,0330895 ! regulation of metal ion transport GO:0010959 50 36 1,000 1,342E-03 0,03462267 ! eye morphogenesis GO:0048592 64 36 1,000 1,342E-03 0,03425038 ! keratinocyte differentiation GO:0030216 55 37 1,000 1,418E-03 0,03578883 ! Notch signaling pathway GO:0007219 64 40 1,000 1,656E-03 0,04135729 ! mesenchymal cell development GO:0014031 70 40 1,000 1,656E-03 0,04092648 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 1,000 1,656E-03 0,04050456 ! developmental growth GO:0048589 70 40 1,000 1,656E-03 0,04009125 ! RNA export from nucleus GO:0006405 57 41 1,000 1,739E-03 0,04168244 ! regulation of epithelial cell proliferation GO:0050678 80 41 1,000 1,739E-03 0,04126561 ! gliogenesis GO:0042063 85 42 1,000 1,824E-03 0,04285975 ! induction of apoptosis by intracellular signals GO:0008629 78 42 1,000 1,824E-03 0,04243956 ! epidermal cell differentiation GO:0009913 61 42 1,000 1,824E-03 0,04202752 ! response to calcium ion GO:0051592 65 43 1,000 1,911E-03 0,04361298 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 1,000 2,001E-03 0,04521231 ! positive regulation of cell cycle GO:0045787 83 45 1,000 2,092E-03 0,04682499 ! regulation of ion transport GO:0043269 60 45 1,000 2,092E-03 0,04638737 ! response to insulin stimulus GO:0032868 71 45 1,000 2,092E-03 0,04595786 ! branching morphogenesis of a tube GO:0048754 85 47 1,000 2,28E-03 0,04962891 ! embryonic skeletal system development GO:0048706 65 47 1,000 2,28E-03 0,04917773 ! response to UV GO:0009411 79 47 1,000 2,28E-03 0,04873469 ! histone modification GO:0016570 81 50 1,000 2,576E-03 0,05458013 ! covalent chromatin modification GO:0016569 90 52 1,000 2,783E-03 0,05844792 ! morphogenesis of a branching structure GO:0001763 99 54 1,000 2,998E-03 0,062406 ! aging GO:0007568 91 57 1,000 3,334E-03 0,06880314 ! nuclear export GO:0051168 85 57 1,000 3,334E-03 0,06821001 ! positive regulation of growth GO:0045927 78 58 1,000 3,45E-03 0,06997682 ! DNA damage response, signal transduction GO:0042770 105 58 1,000 3,45E-03 0,06938379 ! cell projection assembly GO:0030031 90 59 1,000 3,568E-03 0,07114825 ! response to peptide hormone stimulus GO:0043434 97 60 1,000 3,687E-03 0,0729201 ! negative regulation of protein kinase activity GO:0006469 110 62 1,000 3,932E-03 0,07711689 ! multicellular organism reproduction GO:0032504 98 62 1,000 3,932E-03 0,07648479 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of kinase activity GO:0033673 112 63 1,000 4,057E-03 0,07827708 ! embryonic limb morphogenesis GO:0030326 96 63 1,000 4,057E-03 0,07764581 GO:0035113|embryonic appendage morphogenesis, ! developmental maturation GO:0021700 90 63 1,000 4,057E-03 0,07702465 ! myeloid cell differentiation GO:0030099 101 64 1,000 4,184E-03 0,07880461 ! camera-type eye development GO:0043010 103 65 1,000 4,313E-03 0,0805908 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 1,000 4,444E-03 0,08238296 ! protein oligomerization GO:0051259 109 66 1,000 4,444E-03 0,08174433 ! negative regulation of transferase activity GO:0051348 117 66 1,000 4,444E-03 0,08111553 ! appendage morphogenesis GO:0035107 103 67 1,000 4,576E-03 0,08289566 GO:0035108|limb morphogenesis, ! regulation of caspase activity GO:0043281 104 68 1,000 4,71E-03 0,08468147 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 4,71E-03 0,08404477 ! appendage development GO:0048736 108 69 1,000 4,847E-03 0,08582744 GO:0060173|limb development, ! regulation of endopeptidase activity GO:0052548 106 70 1,000 4,984E-03 0,08761544 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 1,000 4,984E-03 0,08697121 ! cell-matrix adhesion GO:0007160 133 71 1,000 5,124E-03 0,08875596 ! regulation of actin cytoskeleton organization GO:0032956 120 72 1,000 5,266E-03 0,09054571 ! homeostasis of number of cells GO:0048872 109 72 1,000 5,266E-03 0,0898943 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 1,000 5,409E-03 0,0916807 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 1,000 5,409E-03 0,09103048 ! regulation of actin filament-based process GO:0032970 122 74 1,000 5,554E-03 0,09281354 ! regulation of neuron differentiation GO:0045664 130 74 1,000 5,554E-03 0,09216449 ! regulation of Rho protein signal transduction GO:0035023 126 74 1,000 5,554E-03 0,09152446 ! regulation of peptidase activity GO:0052547 113 75 1,000 5,701E-03 0,09329634 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 5,701E-03 0,09265732 ! response to metal ion GO:0010038 114 76 1,000 5,849E-03 0,09442602 ! cell-substrate adhesion GO:0031589 141 76 1,000 5,849E-03 0,09378801 ! regulation of Ras GTPase activity GO:0032318 125 76 1,000 5,849E-03 0,09315856 ! positive regulation of ligase activity GO:0051351 114 76 1,000 5,849E-03 0,0925375 ! negative regulation of transport GO:0051051 122 77 1,000 6E-03 0,09428794 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 6E-03 0,09366762 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 127 78 1,000 6,152E-03 0,09541514 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 1,000 6,306E-03 0,09716705 ! tube morphogenesis GO:0035239 140 80 1,000 6,461E-03 0,0989232 ! response to unfolded protein GO:0006986 113 80 1,000 6,461E-03 0,09828907 ! eye development GO:0001654 130 80 1,000 6,461E-03 0,09766303 ! response to inorganic substance GO:0010035 127 81 1,000 6,619E-03 0,09940893 ! regulation of ligase activity GO:0051340 129 82 1,000 6,778E-03 0,10115888 ! positive regulation of protein modification process GO:0031401 126 83 1,000 6,939E-03 0,10291271 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 1,000 7,266E-03 0,10709251 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 127 85 1,000 7,266E-03 0,10643144 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 7,52E-03 0,10948222 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 7,52E-03 0,10881465 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 7,52E-03 0,10815517 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 7,52E-03 0,10750363 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 7,52E-03 0,10685989 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,52E-03 0,10622382 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 7,52E-03 0,10559528 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 7,52E-03 0,10497413 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 7,52E-03 0,10436025 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 7,52E-03 0,1037535 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 7,52E-03 0,10315377 ! response to oxygen radical GO:0000305 11 5 0,000 7,52E-03 0,10256093 ! negative regulation of bone resorption GO:0045779 11 5 0,000 7,52E-03 0,10197487 ! myoblast cell fate commitment GO:0048625 8 5 0,000 7,52E-03 0,10139547 ! nucleotide-sugar transport GO:0015780 8 5 0,000 7,52E-03 0,10082261 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 7,52E-03 0,10025619 ! regulation of interferon-beta production GO:0032648 5 5 0,000 7,52E-03 0,0996961 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 7,52E-03 0,09914224 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 7,52E-03 0,09859449 ! female meiosis GO:0007143 8 5 0,000 7,52E-03 0,09805276 ! nose development GO:0043584 10 5 0,000 7,52E-03 0,09751695 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 7,52E-03 0,09698697 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 7,52E-03 0,09646272 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 7,52E-03 0,0959441 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 7,52E-03 0,09543103 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 7,52E-03 0,09492342 ! cobalt ion transport GO:0006824 9 5 0,000 7,52E-03 0,09442118 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 7,52E-03 0,09392422 ! SMAD protein complex assembly GO:0007183 10 5 0,000 7,52E-03 0,09343247 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 7,52E-03 0,09294585 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 7,52E-03 0,09246426 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 7,52E-03 0,09198764 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 7,52E-03 0,09151591 ! adaptation of signaling pathway GO:0022401 9 5 0,000 7,52E-03 0,09104899 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 7,52E-03 0,09058681 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,52E-03 0,0901293 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 7,52E-03 0,08967639 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,52E-03 0,08922801 ! negative regulation of histone modification GO:0031057 7 5 0,000 7,52E-03 0,08878409 ! malate metabolic process GO:0006108 8 5 0,000 7,52E-03 0,08834457 ! positive regulation of histone modification GO:0031058 6 5 0,000 7,52E-03 0,08790937 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 7,52E-03 0,08747844 ! clathrin coat assembly GO:0048268 11 5 0,000 7,52E-03 0,08705172 ! Notch receptor processing GO:0007220 8 5 0,000 7,52E-03 0,08662914 ! phototransduction, visible light GO:0007603 7 5 0,000 7,52E-03 0,08621064 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,52E-03 0,08579617 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 7,52E-03 0,08538566 ! mating behavior GO:0007617 6 5 0,000 7,52E-03 0,08497906 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 7,52E-03 0,08457631 ! copulation GO:0007620 8 5 0,000 7,52E-03 0,08417737 ! protein maturation by protein folding GO:0022417 13 5 0,000 7,52E-03 0,08378217 ! embryonic hemopoiesis GO:0035162 13 5 0,000 7,52E-03 0,08339067 ! apoptotic cell clearance GO:0043277 14 5 0,000 7,52E-03 0,0830028 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 7,52E-03 0,08261853 ! lipoprotein particle clearance GO:0034381 9 5 0,000 7,52E-03 0,0822378 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 7,52E-03 0,08186056 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 7,52E-03 0,08148677 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 7,52E-03 0,08111637 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 7,52E-03 0,08074933 ! response to axon injury GO:0048678 8 5 0,000 7,52E-03 0,0803856 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,52E-03 0,08002512 ! response to protozoan GO:0001562 10 5 0,000 7,52E-03 0,07966787 ! negative regulation of heart contraction GO:0045822 12 5 0,000 7,52E-03 0,07931379 ! lymph vessel development GO:0001945 8 5 0,000 7,52E-03 0,07896284 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 7,52E-03 0,07861499 ! endochondral ossification GO:0001958 13 5 0,000 7,52E-03 0,07827019 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 7,52E-03 0,07792839 ! single strand break repair GO:0000012 5 5 0,000 7,52E-03 0,07758958 ! parathyroid gland development GO:0060017 8 5 0,000 7,52E-03 0,07725369 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 7,52E-03 0,0769207 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 7,52E-03 0,07659057 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 7,52E-03 0,07626326 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 7,52E-03 0,07593873 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 7,52E-03 0,07561696 ! smooth muscle tissue development GO:0048745 14 5 0,000 7,52E-03 0,0752979 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,52E-03 0,07498152 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 7,52E-03 0,07466779 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 7,52E-03 0,07435668 ! cardiac muscle fiber development GO:0048739 8 5 0,000 7,52E-03 0,07404814 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,52E-03 0,07374216 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 7,52E-03 0,07343869 ! neutrophil mediated immunity GO:0002446 6 5 0,000 7,52E-03 0,07313771 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 7,52E-03 0,07283919 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 7,52E-03 0,0725431 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 7,52E-03 0,0722494 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 7,52E-03 0,07195807 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 7,52E-03 0,07166909 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 7,52E-03 0,07138241 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 7,52E-03 0,07109802 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 7,52E-03 0,07081588 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 7,52E-03 0,07053598 ! tyrosine catabolic process GO:0006572 7 5 0,000 7,52E-03 0,07025828 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 7,52E-03 0,06998275 ! proline biosynthetic process GO:0006561 6 5 0,000 7,52E-03 0,06970938 ! L-serine biosynthetic process GO:0006564 6 5 0,000 7,52E-03 0,06943814 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,52E-03 0,069169 ! polyol catabolic process GO:0046174 7 5 0,000 7,52E-03 0,06890194 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 7,52E-03 0,06863693 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,52E-03 0,06837396 ! sister chromatid cohesion GO:0007062 10 5 0,000 7,52E-03 0,06811299 ! response to ATP GO:0033198 6 5 0,000 7,52E-03 0,067854 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 7,52E-03 0,06759698 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 7,52E-03 0,0673419 ! neutrophil activation GO:0042119 6 5 0,000 7,52E-03 0,06708873 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 7,52E-03 0,06683746 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 7,52E-03 0,06658807 ! response to food GO:0032094 5 5 0,000 7,52E-03 0,06634053 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 7,52E-03 0,06609482 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 7,52E-03 0,06585093 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 7,52E-03 0,06560883 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,52E-03 0,06536851 ! paraxial mesoderm development GO:0048339 9 5 0,000 7,52E-03 0,06512994 ! forebrain neuron development GO:0021884 7 5 0,000 7,52E-03 0,0648931 ! melanosome organization GO:0032438 7 5 0,000 7,52E-03 0,06465798 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 7,52E-03 0,06442456 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 7,52E-03 0,06419281 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 7,52E-03 0,06396273 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 7,52E-03 0,06373429 ! mesodermal cell fate determination GO:0007500 7 5 0,000 7,52E-03 0,06350748 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,52E-03 0,06328228 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 7,52E-03 0,06305867 ! nucleoside salvage GO:0043174 7 5 0,000 7,52E-03 0,06283663 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 7,52E-03 0,06261615 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 7,52E-03 0,06239721 ! negative regulation of platelet activation GO:0010544 8 5 0,000 7,52E-03 0,0621798 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 7,52E-03 0,0619639 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,52E-03 0,06174949 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 7,52E-03 0,06153656 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 7,52E-03 0,06132509 ! early endosome to late endosome transport GO:0045022 11 5 0,000 7,52E-03 0,06111508 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 7,52E-03 0,06090649 ! depyrimidination GO:0045008 8 5 0,000 7,52E-03 0,06069933 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,52E-03 0,06049357 ! 5S class rRNA transcription GO:0042791 8 5 0,000 7,52E-03 0,0602892 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 7,52E-03 0,0600862 ! neuronal ion channel clustering GO:0045161 8 5 0,000 7,52E-03 0,05988457 ! sodium ion homeostasis GO:0055078 6 5 0,000 7,52E-03 0,05968429 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 7,52E-03 0,05948534 ! monocyte differentiation GO:0030224 7 5 0,000 7,52E-03 0,05928772 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 7,52E-03 0,0590914 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 7,52E-03 0,05889638 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 7,52E-03 0,05870264 ! response to UV-C GO:0010225 7 5 0,000 7,52E-03 0,05851017 ! protein targeting to vacuole GO:0006623 6 5 0,000 7,52E-03 0,05831896 ! activated T cell proliferation GO:0050798 7 5 0,000 7,52E-03 0,058129 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 7,52E-03 0,05794027 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 7,52E-03 0,05775276 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 7,52E-03 0,05756646 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 7,52E-03 0,05738136 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 7,52E-03 0,05719744 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 7,52E-03 0,0570147 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 7,52E-03 0,05683313 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 7,52E-03 0,05665271 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 7,52E-03 0,05647343 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 7,52E-03 0,05629528 ! response to cadmium ion GO:0046686 8 5 0,000 7,52E-03 0,05611825 ! melanosome transport GO:0032402 8 5 0,000 7,52E-03 0,05594233 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 7,52E-03 0,05576751 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 7,52E-03 0,05559378 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 7,52E-03 0,05542113 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 7,52E-03 0,05524954 ! positive T cell selection GO:0043368 10 5 0,000 7,52E-03 0,05507902 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 7,52E-03 0,05490955 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 7,52E-03 0,05474111 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 7,52E-03 0,05457371 ! ribosomal subunit assembly GO:0042257 5 5 0,000 7,52E-03 0,05440732 ! base conversion or substitution editing GO:0016553 6 5 0,000 7,52E-03 0,05424195 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 7,52E-03 0,05407758 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 7,52E-03 0,05391421 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 7,52E-03 0,05375181 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 7,52E-03 0,0535904 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 7,52E-03 0,05342995 ! histone demethylation GO:0016577 10 5 0,000 7,52E-03 0,05327045 ! mitotic recombination GO:0006312 10 5 0,000 7,52E-03 0,05311191 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 7,52E-03 0,05295431 ! regulation of sterol transport GO:0032371 7 5 0,000 7,52E-03 0,05279764 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 7,52E-03 0,05264189 ! sympathetic nervous system development GO:0048485 13 5 0,000 7,52E-03 0,05248707 ! enteric nervous system development GO:0048484 9 5 0,000 7,52E-03 0,05233314 ! oxygen homeostasis GO:0032364 8 5 0,000 7,52E-03 0,05218012 ! establishment of planar polarity GO:0001736 7 5 0,000 7,52E-03 0,052028 ! lymphocyte costimulation GO:0031294 12 5 0,000 7,52E-03 0,05187675 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 7,52E-03 0,05172638 ! transcription termination GO:0006353 8 5 0,000 7,52E-03 0,05157689 ! plasminogen activation GO:0031639 5 5 0,000 7,52E-03 0,05142825 ! B cell homeostasis GO:0001782 12 5 0,000 7,52E-03 0,05128047 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 7,52E-03 0,05113353 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 7,52E-03 0,05098744 ! regulation of hair follicle development GO:0051797 9 5 0,000 7,52E-03 0,05084217 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 7,52E-03 0,05069773 ! apical protein localization GO:0045176 8 5 0,000 7,52E-03 0,05055411 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 7,52E-03 0,05041131 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 7,52E-03 0,0502693 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 7,52E-03 0,0501281 ! regulation of centrosome duplication GO:0010824 6 5 0,000 7,52E-03 0,04998768 ! disaccharide metabolic process GO:0005984 9 5 0,000 7,52E-03 0,04984805 ! galactolipid metabolic process GO:0019374 8 5 0,000 7,52E-03 0,0497092 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 7,52E-03 0,04957112 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 7,52E-03 0,0494338 ! determination of adult lifespan GO:0008340 8 5 0,000 7,52E-03 0,04929724 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 7,52E-03 0,04916144 ! somatic stem cell maintenance GO:0035019 14 5 0,000 7,52E-03 0,04902638 ! T cell activation during immune response GO:0002286 9 5 0,000 7,52E-03 0,04889206 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 7,52E-03 0,04875848 ! negative regulation of lipase activity GO:0060192 7 5 0,000 7,52E-03 0,04862562 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 7,52E-03 0,04849348 ! neural plate development GO:0001840 7 5 0,000 7,52E-03 0,04836207 ! regulation of sensory perception GO:0051931 6 5 0,000 7,52E-03 0,04823136 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 7,52E-03 0,04810135 ! regulation of histone acetylation GO:0035065 7 5 0,000 7,52E-03 0,04797205 ! sensory cilium assembly GO:0035058 6 5 0,000 7,52E-03 0,04784344 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 7,52E-03 0,04771551 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 7,52E-03 0,04758827 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,52E-03 0,04746171 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 7,52E-03 0,04733582 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 7,52E-03 0,04721059 ! receptor biosynthetic process GO:0032800 6 5 0,000 7,52E-03 0,04708602 ! penetration of zona pellucida GO:0007341 9 5 0,000 7,52E-03 0,04696211 ! drug metabolic process GO:0017144 5 5 0,000 7,52E-03 0,04683885 ! protein amino acid prenylation GO:0018346 9 5 0,000 7,52E-03 0,04671624 ! organ regeneration GO:0031100 7 5 0,000 7,52E-03 0,04659426 ! carnitine metabolic process GO:0009437 5 5 0,000 7,52E-03 0,04647292 GO:0006577|betaine metabolic process, ! interphase of mitotic cell cycle GO:0051329 166 87 1,000 7,6E-03 0,0468418 ! forebrain development GO:0030900 151 87 1,000 7,6E-03 0,04672045 ! regulation of membrane potential GO:0042391 144 88 1,000 7,769E-03 0,04763899 ! ossification GO:0001503 150 89 1,000 7,94E-03 0,04856322 GO:0060348|bone development, ! interphase GO:0051325 169 89 1,000 7,94E-03 0,04843838 ! regulation of GTPase activity GO:0043087 149 90 1,000 8,113E-03 0,04936618 ! anterior/posterior pattern formation GO:0009952 141 93 1,000 8,642E-03 0,05244945 ! negative regulation of multicellular organismal process GO:0051241 150 93 1,000 8,642E-03 0,05231565 ! regulation of cell adhesion GO:0030155 187 94 1,000 8,822E-03 0,05326726 ! tRNA transcription GO:0009304 11 6 0,000 9,018E-03 0,05431249 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 9,018E-03 0,05417499 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,018E-03 0,05403819 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 9,018E-03 0,05390207 ! regulation of helicase activity GO:0051095 11 6 0,000 9,018E-03 0,05376664 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 9,018E-03 0,05363188 ! sleep GO:0030431 13 6 0,000 9,018E-03 0,05349781 ! positive regulation of axon extension GO:0045773 10 6 0,000 9,018E-03 0,05336439 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 9,018E-03 0,05323165 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 9,018E-03 0,05309956 ! forebrain regionalization GO:0021871 7 6 0,000 9,018E-03 0,05296812 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 9,018E-03 0,05283734 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 9,018E-03 0,0527072 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 9,018E-03 0,0525777 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 9,018E-03 0,05244883 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 9,018E-03 0,05232059 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 9,018E-03 0,05219298 ! neuron adhesion GO:0007158 9 6 0,000 9,018E-03 0,05206599 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 9,018E-03 0,05193962 ! signal peptide processing GO:0006465 8 6 0,000 9,018E-03 0,05181385 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 9,018E-03 0,0516887 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 9,018E-03 0,05156415 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 9,018E-03 0,0514402 ! fibril organization GO:0043206 13 6 0,000 9,018E-03 0,05131684 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 9,018E-03 0,05119407 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 9,018E-03 0,05107189 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 9,018E-03 0,05095029 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 9,018E-03 0,05082927 ! protein refolding GO:0042026 13 6 0,000 9,018E-03 0,05070882 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 9,018E-03 0,05058894 ! rhythmic behavior GO:0007622 14 6 0,000 9,018E-03 0,05046963 ! glial cell fate commitment GO:0021781 17 6 0,000 9,018E-03 0,05035088 ! erythrocyte maturation GO:0043249 7 6 0,000 9,018E-03 0,05023268 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 9,018E-03 0,05011504 ! protein amino acid dealkylation GO:0008214 12 6 0,000 9,018E-03 0,04999795 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 9,018E-03 0,0498814 ! regulation of odontogenesis GO:0042481 8 6 0,000 9,018E-03 0,0497654 ! mechanosensory behavior GO:0007638 8 6 0,000 9,018E-03 0,04964994 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 9,018E-03 0,049535 ! negative regulation of endocytosis GO:0045806 8 6 0,000 9,018E-03 0,04942061 ! response to interferon-gamma GO:0034341 12 6 0,000 9,018E-03 0,04930673 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 9,018E-03 0,04919338 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 9,018E-03 0,04908056 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 9,018E-03 0,04896824 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 9,018E-03 0,04885644 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 9,018E-03 0,04874515 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 9,018E-03 0,04863437 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 9,018E-03 0,04852409 ! cGMP-mediated signaling GO:0019934 11 6 0,000 9,018E-03 0,0484143 ! activation of MAPKKK activity GO:0000185 11 6 0,000 9,018E-03 0,04830502 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 9,018E-03 0,04819622 ! protein lipoylation GO:0009249 10 6 0,000 9,018E-03 0,04808791 ! pigment granule organization GO:0048753 11 6 0,000 9,018E-03 0,04798009 ! drug transport GO:0015893 6 6 0,000 9,018E-03 0,04787276 ! transepithelial chloride transport GO:0030321 10 6 0,000 9,018E-03 0,0477659 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 9,018E-03 0,04765951 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 9,018E-03 0,0475536 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 9,018E-03 0,04744816 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 9,018E-03 0,04734319 ! glutamate catabolic process GO:0006538 11 6 0,000 9,018E-03 0,04723868 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 9,018E-03 0,04713463 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 9,018E-03 0,04703104 ! adenohypophysis development GO:0021984 10 6 0,000 9,018E-03 0,0469279 ! response to pH GO:0009268 10 6 0,000 9,018E-03 0,04682521 ! hyperosmotic response GO:0006972 9 6 0,000 9,018E-03 0,04672297 ! microtubule nucleation GO:0007020 10 6 0,000 9,018E-03 0,04662118 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 9,018E-03 0,04651983 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 9,018E-03 0,04641892 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 9,018E-03 0,04631845 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 9,018E-03 0,04621841 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 9,018E-03 0,0461188 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 9,018E-03 0,04601962 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 9,018E-03 0,04592086 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 9,018E-03 0,04582253 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 9,018E-03 0,04572462 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 9,018E-03 0,04562713 ! purine salvage GO:0043101 9 6 0,000 9,018E-03 0,04553005 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,018E-03 0,04543338 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 9,018E-03 0,04533712 ! nucleoside transport GO:0015858 7 6 0,000 9,018E-03 0,04524127 ! organic alcohol transport GO:0015850 9 6 0,000 9,018E-03 0,04514583 ! T cell mediated immunity GO:0002456 12 6 0,000 9,018E-03 0,04505078 ! folic acid transport GO:0015884 11 6 0,000 9,018E-03 0,04495614 ! male sex determination GO:0030238 11 6 0,000 9,018E-03 0,04486189 ! carnitine transport GO:0015879 8 6 0,000 9,018E-03 0,04476804 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 9,018E-03 0,04467458 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,018E-03 0,0445815 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 9,018E-03 0,04448882 ! positive regulation of exocytosis GO:0045921 9 6 0,000 9,018E-03 0,04439652 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 9,018E-03 0,0443046 ! parturition GO:0007567 13 6 0,000 9,018E-03 0,04421306 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 9,018E-03 0,0441219 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 9,018E-03 0,04403112 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 9,018E-03 0,0439407 ! regulation of centrosome cycle GO:0046605 8 6 0,000 9,018E-03 0,04385066 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 9,018E-03 0,04376099 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 9,018E-03 0,04367168 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 9,018E-03 0,04358273 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 9,018E-03 0,04349415 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 9,018E-03 0,04340593 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 9,018E-03 0,04331806 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 9,018E-03 0,04323055 ! neural nucleus development GO:0048857 12 6 0,000 9,018E-03 0,04314339 ! forebrain morphogenesis GO:0048853 14 6 0,000 9,018E-03 0,04305658 ! hyaluronan metabolic process GO:0030212 7 6 0,000 9,018E-03 0,04297012 ! purine base biosynthetic process GO:0009113 14 6 0,000 9,018E-03 0,04288401 ! interaction with symbiont GO:0051702 9 6 0,000 9,018E-03 0,04279824 ! regulation of dendrite development GO:0050773 13 6 0,000 9,018E-03 0,04271282 ! anterograde axon cargo transport GO:0008089 9 6 0,000 9,018E-03 0,04262773 ! positive regulation of organ growth GO:0046622 7 6 0,000 9,018E-03 0,04254299 ! eating behavior GO:0042755 6 6 0,000 9,018E-03 0,04245858 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 9,018E-03 0,0423745 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 9,018E-03 0,04229076 ! response to copper ion GO:0046688 9 6 0,000 9,018E-03 0,04220734 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 9,018E-03 0,04212426 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 9,018E-03 0,0420415 ! establishment of melanosome localization GO:0032401 9 6 0,000 9,018E-03 0,04195906 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,018E-03 0,04187695 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 9,018E-03 0,04179516 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 9,018E-03 0,04171369 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,018E-03 0,04163253 ! nucleoside catabolic process GO:0009164 7 6 0,000 9,018E-03 0,04155169 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 9,018E-03 0,04147117 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 9,018E-03 0,04139095 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 9,018E-03 0,04131105 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 9,018E-03 0,04123145 ! rhombomere development GO:0021546 6 6 0,000 9,018E-03 0,04115216 ! G2 phase GO:0051319 15 6 0,000 9,018E-03 0,04107317 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 9,018E-03 0,04099449 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 9,018E-03 0,0409161 ! muscle cell proliferation GO:0033002 9 6 0,000 9,018E-03 0,04083802 ! membrane to membrane docking GO:0022614 12 6 0,000 9,018E-03 0,04076023 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 9,018E-03 0,04068274 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 9,018E-03 0,04060554 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 9,018E-03 0,04052864 ! receptor internalization GO:0031623 9 6 0,000 9,018E-03 0,04045203 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 9,018E-03 0,0403757 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 9,018E-03 0,04029966 ! coenzyme A metabolic process GO:0015936 9 6 0,000 9,018E-03 0,04022391 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 9,018E-03 0,04014845 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 9,018E-03 0,04007326 ! peptidyl-histidine modification GO:0018202 10 6 0,000 9,018E-03 0,03999836 ! axonal fasciculation GO:0007413 10 6 0,000 9,018E-03 0,03992374 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 9,018E-03 0,03984939 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 9,018E-03 0,03977532 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 9,018E-03 0,03970153 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 9,018E-03 0,039628 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,018E-03 0,03955475 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 9,018E-03 0,03948178 ! progesterone metabolic process GO:0042448 8 6 0,000 9,018E-03 0,03940906 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 9,018E-03 0,03933662 ! glycolipid catabolic process GO:0019377 14 6 0,000 9,018E-03 0,03926444 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 9,018E-03 0,03919253 ! negative regulation of axon extension GO:0030517 13 6 0,000 9,018E-03 0,03912088 ! removal of superoxide radicals GO:0019430 10 6 0,000 9,018E-03 0,03904949 ! triglyceride catabolic process GO:0019433 8 6 0,000 9,018E-03 0,03897836 ! protein modification by small protein removal GO:0070646 10 6 0,000 9,018E-03 0,03890749 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 9,018E-03 0,03883688 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 9,018E-03 0,03876653 ! glial cell migration GO:0008347 11 6 0,000 9,018E-03 0,03869642 ! blastocyst growth GO:0001832 17 6 0,000 9,018E-03 0,03862657 ! pigment granule transport GO:0051904 12 6 0,000 9,018E-03 0,03855698 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 9,018E-03 0,03848763 ! cerebellar cortex formation GO:0021697 9 6 0,000 9,018E-03 0,03841853 ! catecholamine transport GO:0051937 7 6 0,000 9,018E-03 0,03834968 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 9,018E-03 0,03828108 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 9,018E-03 0,03821272 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,018E-03 0,0381446 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 9,018E-03 0,03807673 ! spindle assembly GO:0051225 6 6 0,000 9,018E-03 0,0380091 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 9,018E-03 0,03794171 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 9,018E-03 0,03787455 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 9,018E-03 0,03780764 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 9,018E-03 0,03774096 ! NAD biosynthetic process GO:0009435 9 6 0,000 9,018E-03 0,03767451 ! positive regulation of coagulation GO:0050820 11 6 0,000 9,018E-03 0,0376083 ! cellular anion homeostasis GO:0030002 9 6 0,000 9,018E-03 0,03754232 GO:0055081|anion homeostasis, ! female pregnancy GO:0007565 148 96 1,000 9,186E-03 0,03817607 ! regulation of neurogenesis GO:0050767 179 97 1,000 9,371E-03 0,03887539 ! response to virus GO:0009615 141 98 1,000 9,557E-03 0,03957913 ! cell fate commitment GO:0045165 165 99 1,000 9,745E-03 0,04028727 ! behavioral response to cocaine GO:0048148 13 7 0,000 0,01051305 0,04338688 ! autophagic vacuole formation GO:0000045 12 7 0,000 0,01051305 0,04331156 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01051305 0,0432365 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 0,01051305 0,04316169 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 0,01051305 0,04308715 ! prostate gland development GO:0030850 11 7 0,000 0,01051305 0,04301286 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01051305 0,04293883 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 0,01051305 0,04286505 ! synaptonemal complex assembly GO:0007130 11 7 0,000 0,01051305 0,04279152 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 0,01051305 0,04271825 ! male meiosis GO:0007140 10 7 0,000 0,01051305 0,04264523 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01051305 0,04257245 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 0,01051305 0,04249993 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01051305 0,04242765 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01051305 0,04235562 ! oligopeptide transport GO:0006857 11 7 0,000 0,01051305 0,04228383 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01051305 0,04221228 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 0,01051305 0,04214098 ! establishment of tissue polarity GO:0007164 10 7 0,000 0,01051305 0,04206991 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 0,01051305 0,04199909 ! RNA methylation GO:0001510 11 7 0,000 0,01051305 0,0419285 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 0,01051305 0,04185815 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 0,01051305 0,04178804 ! pericardium development GO:0060039 9 7 0,000 0,01051305 0,04171816 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01051305 0,04164851 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01051305 0,0415791 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01051305 0,04150991 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01051305 0,04144096 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01051305 0,04137224 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01051305 0,04130374 ! opsonization GO:0008228 9 7 0,000 0,01051305 0,04123547 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 0,01051305 0,04116742 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01051305 0,0410996 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 0,01051305 0,041032 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 0,01051305 0,04096463 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01051305 0,04089747 ! chemosensory behavior GO:0007635 9 7 0,000 0,01051305 0,04083054 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01051305 0,04076382 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01051305 0,04069732 ! leukocyte degranulation GO:0043299 11 7 0,000 0,01051305 0,04063104 ! positive regulation of glycolysis GO:0045821 13 7 0,000 0,01051305 0,04056497 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 0,01051305 0,04049912 ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01051305 0,04043348 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01051305 0,04036806 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 0,01051305 0,04030284 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01051305 0,04023784 ! spinal cord patterning GO:0021511 9 7 0,000 0,01051305 0,04017304 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01051305 0,04010845 ! thymic T cell selection GO:0045061 15 7 0,000 0,01051305 0,04004407 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 0,01051305 0,0399799 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01051305 0,03991593 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01051305 0,03985217 ! ovulation GO:0030728 8 7 0,000 0,01051305 0,03978861 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 0,01051305 0,03972525 ! histidine metabolic process GO:0006547 7 7 0,000 0,01051305 0,0396621 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 0,01051305 0,03959914 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01051305 0,03953638 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 0,01051305 0,03947383 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 0,01051305 0,03941147 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 0,01051305 0,0393493 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01051305 0,03928734 ! endosome organization GO:0007032 10 7 0,000 0,01051305 0,03922556 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01051305 0,03916399 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 0,01051305 0,0391026 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 0,01051305 0,03904141 ! urea metabolic process GO:0019627 9 7 0,000 0,01051305 0,0389804 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 0,01051305 0,03891959 ! vesicle fusion GO:0006906 15 7 0,000 0,01051305 0,03885897 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 0,01051305 0,03879854 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 0,01051305 0,03873829 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01051305 0,03867823 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 0,01051305 0,03861836 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 0,01051305 0,03855867 ! organ growth GO:0035265 13 7 0,000 0,01051305 0,03849916 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 0,01051305 0,03843984 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01051305 0,03838071 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 0,01051305 0,03832175 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 0,01051305 0,03826297 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 0,01051305 0,03820438 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 0,01051305 0,03814596 ! rRNA modification GO:0000154 12 7 0,000 0,01051305 0,03808772 ! negative regulation of translational initiation GO:0045947 9 7 0,000 0,01051305 0,03802966 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 0,01051305 0,03797178 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 0,01051305 0,03791407 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01051305 0,03785654 ! response to UV-B GO:0010224 11 7 0,000 0,01051305 0,03779918 ! astrocyte development GO:0014002 15 7 0,000 0,01051305 0,03774199 ! intermediate filament organization GO:0045109 12 7 0,000 0,01051305 0,03768498 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01051305 0,03762814 ! fibrinolysis GO:0042730 9 7 0,000 0,01051305 0,03757147 ! peptidyl-arginine modification GO:0018195 9 7 0,000 0,01051305 0,03751498 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 0,01051305 0,03745865 ! blastoderm segmentation GO:0007350 11 7 0,000 0,01051305 0,03740249 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01051305 0,03734649 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01051305 0,03729067 ! DNA topological change GO:0006265 10 7 0,000 0,01051305 0,03723501 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 0,01051305 0,03717952 ! melanosome localization GO:0032400 10 7 0,000 0,01051305 0,03712419 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 0,01051305 0,03706903 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 0,01051305 0,03701403 ! mast cell activation GO:0045576 10 7 0,000 0,01051305 0,0369592 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01051305 0,03690452 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 0,01051305 0,03685001 ! gas homeostasis GO:0033483 12 7 0,000 0,01051305 0,03679566 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 0,01051305 0,03674147 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 0,01051305 0,03668744 ! Schwann cell development GO:0014044 16 7 0,000 0,01051305 0,03663357 ! dendrite morphogenesis GO:0048813 12 7 0,000 0,01051305 0,03657985 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 0,01051305 0,03652629 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 0,01051305 0,03647289 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 0,01051305 0,03641965 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 0,01051305 0,03636656 ! neural tube patterning GO:0021532 8 7 0,000 0,01051305 0,03631362 ! histone ubiquitination GO:0016574 10 7 0,000 0,01051305 0,03626084 ! regulation of meiosis GO:0040020 12 7 0,000 0,01051305 0,03620821 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 0,01051305 0,03615574 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 0,01051305 0,03610341 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01051305 0,03605124 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 0,01051305 0,03599922 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01051305 0,03594735 ! regulation of cell division GO:0051302 9 7 0,000 0,01051305 0,03589562 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 0,01051305 0,03584405 ! neutrophil homeostasis GO:0001780 8 7 0,000 0,01051305 0,03579262 ! regulation of macrophage activation GO:0043030 12 7 0,000 0,01051305 0,03574134 ! negative regulation of nuclear division GO:0051784 18 7 0,000 0,01051305 0,03569021 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01051305 0,03563923 ! diuresis GO:0030146 11 7 0,000 0,01051305 0,03558839 GO:0030147|natriuresis, ! thiamin metabolic process GO:0006772 8 7 0,000 0,01051305 0,03553769 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 0,01051305 0,03548714 GO:0002688|regulation of leukocyte chemotaxis, ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 0,01051305 0,03543673 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01051305 0,03538647 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01051305 0,03533634 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01051305 0,03528636 ! lymph node development GO:0048535 9 7 0,000 0,01051305 0,03523652 ! anterior/posterior axis specification GO:0009948 11 7 0,000 0,01051305 0,03518682 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 0,01051305 0,03513727 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 0,01051305 0,03508785 ! positive regulation of glucose import GO:0046326 7 7 0,000 0,01051305 0,03503857 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01051305 0,03498942 ! ATP catabolic process GO:0006200 10 7 0,000 0,01051305 0,03494042 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01051305 0,03489155 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 0,01051305 0,03484282 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01051305 0,03479422 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 0,01051305 0,03474576 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01051305 0,03469744 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 0,01051305 0,03464925 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01051305 0,03460119 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01051305 0,03455327 ! muscle adaptation GO:0043500 12 7 0,000 0,01051305 0,03450548 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01051305 0,03445782 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 0,01051305 0,03441029 ! retina homeostasis GO:0001895 9 7 0,000 0,01051305 0,03436289 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01051305 0,03431562 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 0,01051305 0,03426849 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 0,01051305 0,03422148 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 0,01051305 0,0341746 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01051305 0,03412785 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 0,01200616 0,03892161 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 0,01200616 0,03886851 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01200616 0,03881556 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01200616 0,03876275 ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 0,01200616 0,03871008 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 0,01200616 0,03865756 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 0,01200616 0,03860518 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 0,01200616 0,03855294 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 0,01200616 0,03850084 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01200616 0,03844888 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01200616 0,03839706 ! neutral lipid catabolic process GO:0046461 11 8 0,000 0,01200616 0,03834538 ! N-glycan processing GO:0006491 12 8 0,000 0,01200616 0,03829384 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01200616 0,03824244 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 0,01200616 0,03819118 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 0,01200616 0,03814005 ! mRNA stabilization GO:0048255 16 8 0,000 0,01200616 0,03808906 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 0,01200616 0,03803821 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01200616 0,03798749 ! lipoprotein transport GO:0042953 14 8 0,000 0,01200616 0,03793691 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01200616 0,03788646 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01200616 0,03783615 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01200616 0,03778597 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01200616 0,03773592 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 0,01200616 0,037686 ! bile acid and bile salt transport GO:0015721 12 8 0,000 0,01200616 0,03763622 ! ganglioside metabolic process GO:0001573 16 8 0,000 0,01200616 0,03758657 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 0,01200616 0,03753705 ! reflex GO:0060004 16 8 0,000 0,01200616 0,03748766 ! positive regulation of isotype switching GO:0045830 16 8 0,000 0,01200616 0,0374384 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01200616 0,03738926 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 0,01200616 0,03734026 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01200616 0,03729139 ! glycerolipid catabolic process GO:0046503 11 8 0,000 0,01200616 0,03724264 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 0,01200616 0,03719402 ! hemoglobin metabolic process GO:0020027 12 8 0,000 0,01200616 0,03714553 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01200616 0,03709716 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 0,01200616 0,03704892 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 0,01200616 0,0370008 ! adrenal gland development GO:0030325 18 8 0,000 0,01200616 0,03695281 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 0,01200616 0,03690495 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01200616 0,0368572 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01200616 0,03680959 ! proline metabolic process GO:0006560 9 8 0,000 0,01200616 0,03676209 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01200616 0,03671472 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 0,01200616 0,03666746 ! regulation of pigmentation during development GO:0048070 18 8 0,000 0,01200616 0,03662033 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 0,01200616 0,03657332 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 0,01200616 0,03652643 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01200616 0,03647967 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01200616 0,03643302 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 0,01200616 0,03638649 ! galactose metabolic process GO:0006012 14 8 0,000 0,01200616 0,03634008 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01200616 0,03629378 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01200616 0,03624761 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01200616 0,03620155 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 0,01200616 0,03615561 ! ruffle organization GO:0031529 12 8 0,000 0,01200616 0,03610978 ! osteoblast development GO:0002076 14 8 0,000 0,01200616 0,03606407 ! macroautophagy GO:0016236 14 8 0,000 0,01200616 0,03601848 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01200616 0,035973 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01200616 0,03592764 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 0,01200616 0,03588239 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01200616 0,03583726 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 0,01200616 0,03579224 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 0,01200616 0,03574733 ! protein retention in ER lumen GO:0006621 16 8 0,000 0,01200616 0,03570253 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 0,01200616 0,03565785 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 0,01200616 0,03561327 ! regulation of circadian rhythm GO:0042752 13 8 0,000 0,01200616 0,03556881 ! pigment granule localization GO:0051875 14 8 0,000 0,01200616 0,03552446 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 0,01200616 0,03548022 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 0,01200616 0,03543609 ! response to tropane GO:0014073 14 8 0,000 0,01200616 0,03539207 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 0,01200616 0,03534816 ! embryonic axis specification GO:0000578 12 8 0,000 0,01200616 0,03530436 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 0,01200616 0,03526067 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 0,01200616 0,03521708 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 0,01200616 0,0351736 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01200616 0,03513023 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01200616 0,03508697 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01200616 0,03504381 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 0,01200616 0,03500076 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 0,01200616 0,03495781 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 0,01200616 0,03491497 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 0,01200616 0,03487224 ! establishment of nucleus localization GO:0040023 14 8 0,000 0,01200616 0,03482961 ! icosanoid secretion GO:0032309 12 8 0,000 0,01200616 0,03478708 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 0,01200616 0,03474466 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 0,01200616 0,03470234 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 0,01200616 0,03466012 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 0,01200616 0,03461801 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 0,01200616 0,03457599 ! S phase GO:0051320 8 8 0,000 0,01200616 0,03453408 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 0,01200616 0,03449228 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 0,01200616 0,03445057 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 0,01200616 0,03440896 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01200616 0,03436745 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 0,01200616 0,03432605 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01200616 0,03428474 ! melanin biosynthetic process GO:0042438 11 8 0,000 0,01200616 0,03424353 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01200616 0,03420242 ! regulation of synaptogenesis GO:0051963 12 8 0,000 0,01200616 0,03416141 ! hormone catabolic process GO:0042447 13 8 0,000 0,01200616 0,0341205 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 0,01200616 0,03407969 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01200616 0,03403897 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 0,01200616 0,03399835 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01200616 0,03395783 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01200616 0,0339174 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01200616 0,03387707 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 0,01200616 0,03383684 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01200616 0,0337967 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01200616 0,03375666 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 0,01200616 0,03371671 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 0,01200616 0,03367685 ! negative regulation of B cell activation GO:0050869 17 8 0,000 0,01200616 0,03363709 ! behavioral response to nicotine GO:0035095 13 8 0,000 0,01200616 0,03359743 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01200616 0,03355786 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 0,01200616 0,03351838 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 0,01200616 0,03347899 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 0,01200616 0,03343969 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 0,01200616 0,03340049 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,0134971 0,03750423 ! regulation of developmental growth GO:0048638 14 9 0,000 0,0134971 0,03746036 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 0,0134971 0,0374166 ! telencephalon cell migration GO:0022029 16 9 0,000 0,0134971 0,03737294 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 0,0134971 0,03732938 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 0,0134971 0,03728593 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 0,0134971 0,03724257 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 0,0134971 0,03719932 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 0,0134971 0,03715616 ! cell volume homeostasis GO:0006884 14 9 0,000 0,0134971 0,03711311 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 0,0134971 0,03707015 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 0,0134971 0,0370273 ! UTP metabolic process GO:0046051 10 9 0,000 0,0134971 0,03698454 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 0,0134971 0,03694188 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 0,0134971 0,03689932 ! smoothened signaling pathway GO:0007224 10 9 0,000 0,0134971 0,03685686 ! protein complex disassembly GO:0043241 17 9 0,000 0,0134971 0,0368145 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,0134971 0,03677223 ! estrogen metabolic process GO:0008210 16 9 0,000 0,0134971 0,03673006 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,0134971 0,03668799 ! photoreceptor cell development GO:0042461 17 9 0,000 0,0134971 0,03664601 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 0,0134971 0,03660413 ! microtubule bundle formation GO:0001578 14 9 0,000 0,0134971 0,03656234 ! T-helper 1 type immune response GO:0042088 13 9 0,000 0,0134971 0,03652065 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 0,0134971 0,03647906 ! lung alveolus development GO:0048286 18 9 0,000 0,0134971 0,03643756 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,0134971 0,03639615 ! pseudouridine synthesis GO:0001522 10 9 0,000 0,0134971 0,03635484 ! endothelial cell differentiation GO:0045446 17 9 0,000 0,0134971 0,03631362 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,0134971 0,03627249 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,0134971 0,03623146 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,0134971 0,03619052 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,0134971 0,03614967 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 0,0134971 0,03610892 ! astrocyte differentiation GO:0048708 17 9 0,000 0,0134971 0,03606826 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 0,0134971 0,03602768 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 0,0134971 0,0359872 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0134971 0,03594681 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 0,0134971 0,03590651 ! reverse cholesterol transport GO:0043691 17 9 0,000 0,0134971 0,03586631 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 0,0134971 0,03582619 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 0,0134971 0,03578616 ! macrophage activation GO:0042116 14 9 0,000 0,0134971 0,03574622 ! multicellular organism growth GO:0035264 16 9 0,000 0,0134971 0,03570637 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 0,0134971 0,0356666 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,0134971 0,03562693 ! neuron apoptosis GO:0051402 12 9 0,000 0,0134971 0,03558735 ! lens development in camera-type eye GO:0002088 11 9 0,000 0,0134971 0,03554785 ! positive regulation of vasodilation GO:0045909 14 9 0,000 0,0134971 0,03550844 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,0134971 0,03546912 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 0,0134971 0,03542988 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,0134971 0,03539073 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 0,0134971 0,03535167 ! Schwann cell differentiation GO:0014037 20 9 0,000 0,0134971 0,03531269 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 0,0134971 0,0352738 ! regulation of gliogenesis GO:0014013 21 9 0,000 0,0134971 0,035235 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 0,0134971 0,03519628 ! oligodendrocyte development GO:0014003 13 9 0,000 0,0134971 0,03515764 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 0,0134971 0,03511909 ! segment specification GO:0007379 11 9 0,000 0,0134971 0,03508063 ! cellular extravasation GO:0045123 12 9 0,000 0,0134971 0,03504224 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0134971 0,03500395 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 0,0134971 0,03496573 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,0134971 0,0349276 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0134971 0,03488955 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 0,0134971 0,03485159 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 0,0134971 0,03481371 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 0,0134971 0,03477591 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 0,0134971 0,03473819 ! response to amine stimulus GO:0014075 13 9 0,000 0,0134971 0,03470055 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 0,0134971 0,034663 ! erythrocyte development GO:0048821 13 9 0,000 0,0134971 0,03462553 ! renal water homeostasis GO:0003091 13 9 0,000 0,0134971 0,03458813 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 0,0134971 0,03455082 ! nucleosome disassembly GO:0006337 13 9 0,000 0,0134971 0,03451359 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 0,0134971 0,03447644 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 0,0134971 0,03443937 ! induction of an organ GO:0001759 13 9 0,000 0,0134971 0,03440238 ! leukocyte activation during immune response GO:0002366 15 9 0,000 0,0134971 0,03436546 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 0,0134971 0,03432863 ! cerebellum morphogenesis GO:0021587 13 9 0,000 0,0134971 0,03429187 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 0,0134971 0,0342552 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0134971 0,0342186 ! sterol catabolic process GO:0016127 11 9 0,000 0,0134971 0,03418208 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 0,0134971 0,03414564 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,0134971 0,03410928 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 0,0134971 0,03407299 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 0,0134971 0,03403678 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 0,0134971 0,03400065 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 0,0134971 0,03396459 ! prophase GO:0051324 12 9 0,000 0,0134971 0,03392861 ! neuroblast proliferation GO:0007405 19 9 0,000 0,0134971 0,03389271 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 0,0134971 0,03385688 ! peptidyl-threonine modification GO:0018210 22 9 0,000 0,0134971 0,03382113 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 0,0134971 0,03378545 ! ubiquinone metabolic process GO:0006743 11 9 0,000 0,0134971 0,03374985 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 0,0134971 0,03371433 ! acid secretion GO:0046717 14 9 0,000 0,0134971 0,03367888 ! purine base metabolic process GO:0006144 18 9 0,000 0,0134971 0,0336435 ! detection of calcium ion GO:0005513 13 9 0,000 0,0134971 0,0336082 ! myeloid cell homeostasis GO:0002262 10 9 0,000 0,0134971 0,03357297 ! regulation of fibrinolysis GO:0051917 14 9 0,000 0,0134971 0,03353781 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,0134971 0,03350273 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 0,0134971 0,03346772 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 0,0134971 0,03343279 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,0134971 0,03339793 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0134971 0,03336314 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 0,0134971 0,03332842 ! prepulse inhibition GO:0060134 14 9 0,000 0,0134971 0,03329377 ! sequestering of metal ion GO:0051238 12 9 0,000 0,0134971 0,0332592 ! lamellipodium assembly GO:0030032 12 9 0,000 0,0134971 0,0332247 ! regulation of embryonic development GO:0045995 17 9 0,000 0,0134971 0,03319027 ! mitochondrion localization GO:0051646 15 9 0,000 0,0134971 0,03315591 ! localization within membrane GO:0051668 15 9 0,000 0,0134971 0,03312162 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01498586 0,03673703 ! axon extension GO:0048675 13 10 0,000 0,01498586 0,03669911 ! neuron fate specification GO:0048665 12 10 0,000 0,01498586 0,03666128 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,01498586 0,03662352 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,01498586 0,03658585 ! associative learning GO:0008306 19 10 0,000 0,01498586 0,03654824 ! positive regulation of B cell proliferation GO:0030890 14 10 0,000 0,01498586 0,03651072 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,01498586 0,03647327 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01498586 0,0364359 ! CTP metabolic process GO:0046036 11 10 0,000 0,01498586 0,03639861 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,01498586 0,03636139 ! GTP metabolic process GO:0046039 11 10 0,000 0,01498586 0,03632425 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01498586 0,03628719 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,01498586 0,0362502 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! social behavior GO:0035176 15 10 0,000 0,01498586 0,03621328 ! sulfate transport GO:0008272 12 10 0,000 0,01498586 0,03617644 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,01498586 0,03613968 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,01498586 0,03610299 ! artery development GO:0060840 20 10 0,000 0,01498586 0,03606637 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,01498586 0,03602983 ! response to pain GO:0048265 20 10 0,000 0,01498586 0,03599336 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,01498586 0,03595697 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,01498586 0,03592065 ! phospholipid efflux GO:0033700 17 10 0,000 0,01498586 0,0358844 ! hippocampus development GO:0021766 19 10 0,000 0,01498586 0,03584823 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,01498586 0,03581213 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,01498586 0,0357761 ! blood vessel remodeling GO:0001974 23 10 0,000 0,01498586 0,03574014 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01498586 0,03570426 ! pathogenesis GO:0009405 13 10 0,000 0,01498586 0,03566845 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01498586 0,03563271 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,01498586 0,03559704 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,01498586 0,03556144 ! protein targeting to ER GO:0045047 21 10 0,000 0,01498586 0,03552592 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,01498586 0,03549046 ! arginine catabolic process GO:0006527 12 10 0,000 0,01498586 0,03545508 ! melanocyte differentiation GO:0030318 16 10 0,000 0,01498586 0,03541976 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,01498586 0,03538452 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01498586 0,03534935 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,01498586 0,03531424 ! B cell proliferation GO:0042100 16 10 0,000 0,01498586 0,03527921 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,01498586 0,03524424 ! mannose metabolic process GO:0006013 11 10 0,000 0,01498586 0,03520935 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01498586 0,03517452 ! forebrain cell migration GO:0021885 17 10 0,000 0,01498586 0,03513976 ! lipid digestion GO:0044241 15 10 0,000 0,01498586 0,03510508 ! substrate-bound cell migration GO:0006929 11 10 0,000 0,01498586 0,03507046 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01498586 0,0350359 ! receptor clustering GO:0043113 18 10 0,000 0,01498586 0,03500142 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01498586 0,034967 ! UV protection GO:0009650 14 10 0,000 0,01498586 0,03493265 ! entry into host cell GO:0030260 21 10 0,000 0,01498586 0,03489837 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,01498586 0,03486416 ! behavioral fear response GO:0001662 19 10 0,000 0,01498586 0,03483001 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01498586 0,03479593 ! negative regulation of ossification GO:0030279 21 10 0,000 0,01498586 0,03476192 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,01498586 0,03472797 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,01498586 0,03469409 ! response to dsRNA GO:0043331 19 10 0,000 0,01498586 0,03466027 ! DNA ligation GO:0006266 16 10 0,000 0,01498586 0,03462653 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,01498586 0,03459284 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,01498586 0,03455922 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01498586 0,03452567 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01498586 0,03449218 ! postreplication repair GO:0006301 16 10 0,000 0,01498586 0,03445876 ! fucose catabolic process GO:0019317 17 10 0,000 0,01498586 0,0344254 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,01498586 0,03439211 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01498586 0,03435888 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,01498586 0,03432572 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,01498586 0,03429262 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,01498586 0,03425958 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01498586 0,0342266 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,01498586 0,03419369 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,01498586 0,03416085 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,01498586 0,03412806 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,01498586 0,03409534 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,01498586 0,03406268 ! oocyte differentiation GO:0009994 14 10 0,000 0,01498586 0,03403009 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,01498586 0,03399755 ! spleen development GO:0048536 17 10 0,000 0,01498586 0,03396508 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,01498586 0,03393267 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,01498586 0,03390033 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 0,01498586 0,03386804 ! embryonic gut development GO:0048566 13 10 0,000 0,01498586 0,03383582 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,01498586 0,03380365 ! cerebellar cortex development GO:0021695 14 10 0,000 0,01498586 0,03377155 ! activation of innate immune response GO:0002218 10 10 0,000 0,01498586 0,03373951 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01498586 0,03370753 ! insulin secretion GO:0030073 18 10 0,000 0,01498586 0,03367561 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 0,01498586 0,03364375 ! response to nicotine GO:0035094 18 10 0,000 0,01498586 0,03361195 ! establishment of cell polarity GO:0030010 12 10 0,000 0,01498586 0,03358021 ! nucleus localization GO:0051647 16 10 0,000 0,01498586 0,03354853 ! regulation of synapse organization GO:0050807 14 10 0,000 0,01498586 0,03351691 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,01647245 0,03680708 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,01647245 0,03677245 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,01647245 0,03673789 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,01647245 0,0367034 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,01647245 0,03666897 ! virus-host interaction GO:0019048 20 11 0,000 0,01647245 0,0366346 ! thyroid gland development GO:0030878 20 11 0,000 0,01647245 0,0366003 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,01647245 0,03656606 GO:0006740|NADPH regeneration, ! non-recombinational repair GO:0000726 19 11 0,000 0,01647245 0,03653189 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,01647245 0,03649778 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,01647245 0,03646373 ! Golgi vesicle budding GO:0048194 18 11 0,000 0,01647245 0,03642975 ! elastic fiber assembly GO:0048251 17 11 0,000 0,01647245 0,03639583 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,01647245 0,03636197 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,01647245 0,03632818 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,01647245 0,03629445 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,01647245 0,03626078 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,01647245 0,03622717 ! bone resorption GO:0045453 16 11 0,000 0,01647245 0,03619363 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,01647245 0,03616015 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,01647245 0,03612673 ! ventral spinal cord development GO:0021517 15 11 0,000 0,01647245 0,03609337 ! regulated secretory pathway GO:0045055 15 11 0,000 0,01647245 0,03606007 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 0,01647245 0,03602684 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,01647245 0,03599366 ! syncytium formation GO:0006949 15 11 0,000 0,01647245 0,03596055 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01647245 0,0359275 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,01647245 0,03589451 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,01647245 0,03586158 ! Golgi organization GO:0007030 19 11 0,000 0,01647245 0,03582871 ! response to X-ray GO:0010165 19 11 0,000 0,01647245 0,0357959 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,01647245 0,03576315 ! adult heart development GO:0007512 12 11 0,000 0,01647245 0,03573046 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01647245 0,03569783 ! epithelial cell development GO:0002064 16 11 0,000 0,01647245 0,03566525 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,01647245 0,03563274 ! temperature homeostasis GO:0001659 16 11 0,000 0,01647245 0,03560029 ! L-glutamate transport GO:0015813 15 11 0,000 0,01647245 0,0355679 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,01647245 0,03553556 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01647245 0,03550329 ! motor axon guidance GO:0008045 17 11 0,000 0,01647245 0,03547107 ! copper ion homeostasis GO:0055070 15 11 0,000 0,01647245 0,03543891 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,01647245 0,03540681 ! regulation of bone resorption GO:0045124 27 11 0,000 0,01647245 0,03537477 ! stem cell development GO:0048864 30 11 0,000 0,01647245 0,03534278 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,01647245 0,03531086 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,01647245 0,03527899 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,01647245 0,03524718 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,01647245 0,03521542 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01647245 0,03518373 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,01647245 0,03515209 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01647245 0,0351205 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,01647245 0,03508898 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,01647245 0,03505751 ! cranial nerve development GO:0021545 14 11 0,000 0,01647245 0,03502609 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01647245 0,03499473 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01647245 0,03496343 ! salivary gland development GO:0007431 24 11 0,000 0,01647245 0,03493219 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,01647245 0,034901 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,01647245 0,03486986 ! musculoskeletal movement GO:0050881 16 11 0,000 0,01647245 0,03483879 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,01647245 0,03480776 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01647245 0,0347768 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01647245 0,03474588 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 19 11 0,000 0,01647245 0,03471503 ! cholesterol efflux GO:0033344 20 11 0,000 0,01647245 0,03468422 ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,01647245 0,03465347 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,01647245 0,03462278 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 0,01647245 0,03459214 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01647245 0,03456155 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,01647245 0,03453102 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01647245 0,03450055 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,01647245 0,03447012 ! defense response to fungus GO:0050832 13 11 0,000 0,01647245 0,03443975 ! lysogeny GO:0030069 20 11 0,000 0,01647245 0,03440944 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,01647245 0,03437917 ! acrosome reaction GO:0007340 14 11 0,000 0,01647245 0,03434896 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,01647245 0,0343188 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,01647245 0,0342887 ! rRNA transcription GO:0009303 19 12 0,000 0,01795687 0,03734588 ! reproductive cellular process GO:0048610 15 12 0,000 0,01795687 0,03731318 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01795687 0,03728053 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01795687 0,03724794 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01795687 0,03721541 ! phosphate transport GO:0006817 15 12 0,000 0,01795687 0,03718294 ! peroxisomal transport GO:0043574 22 12 0,000 0,01795687 0,03715052 ! mating GO:0007618 16 12 0,000 0,01795687 0,03711816 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01795687 0,03708586 ! heart looping GO:0001947 15 12 0,000 0,01795687 0,03705361 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01795687 0,03702141 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01795687 0,03698928 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01795687 0,0369572 ! T cell selection GO:0045058 25 12 0,000 0,01795687 0,03692517 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01795687 0,0368932 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,01795687 0,03686129 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01795687 0,03682943 ! plasma membrane organization GO:0007009 19 12 0,000 0,01795687 0,03679762 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01795687 0,03676587 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01795687 0,03673418 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01795687 0,03670254 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01795687 0,03667095 ! monoamine transport GO:0015844 14 12 0,000 0,01795687 0,03663942 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01795687 0,03660795 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01795687 0,03657652 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01795687 0,03654515 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01795687 0,03651384 ! regulation of organ growth GO:0046620 14 12 0,000 0,01795687 0,03648258 ! vasoconstriction GO:0042310 18 12 0,000 0,01795687 0,03645137 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01795687 0,03642021 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01795687 0,03638911 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01795687 0,03635806 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01795687 0,03632707 ! histone acetylation GO:0016573 27 12 0,000 0,01795687 0,03629612 ! DNA methylation GO:0006306 19 12 0,000 0,01795687 0,03626523 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,01795687 0,03623439 ! protein sumoylation GO:0016925 14 12 0,000 0,01795687 0,03620361 ! chromatin silencing GO:0006342 23 12 0,000 0,01795687 0,03617288 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01795687 0,0361422 ! gland morphogenesis GO:0022612 24 12 0,000 0,01795687 0,03611157 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01795687 0,03608099 ! zymogen activation GO:0031638 16 12 0,000 0,01795687 0,03605046 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01795687 0,03601999 ! nucleosome positioning GO:0016584 13 12 0,000 0,01795687 0,03598957 ! T cell homeostasis GO:0043029 22 12 0,000 0,01795687 0,0359592 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01795687 0,03592888 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01795687 0,03589861 ! response to gamma radiation GO:0010332 21 12 0,000 0,01795687 0,03586839 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01795687 0,03583822 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01795687 0,03580811 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01795687 0,03577804 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01795687 0,03574803 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01795687 0,03571806 ! male genitalia development GO:0030539 15 12 0,000 0,01795687 0,03568815 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01795687 0,03565828 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01795687 0,03562847 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01795687 0,0355987 ! developmental induction GO:0031128 16 12 0,000 0,01795687 0,03556899 GO:0045168|cell-cell signaling involved in cell fate specification, ! response to cold GO:0009409 15 12 0,000 0,01795687 0,03553932 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01795687 0,03550971 ! respiratory burst GO:0045730 22 13 0,000 0,01943912 0,03840886 ! lactation GO:0007595 22 13 0,000 0,01943912 0,0383769 ! tRNA modification GO:0006400 15 13 0,000 0,01943912 0,038345 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,01943912 0,03831316 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,01943912 0,03828136 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01943912 0,03824962 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,01943912 0,03821793 ! water transport GO:0006833 21 13 0,000 0,01943912 0,03818629 GO:0042044|fluid transport, ! regulation of B cell proliferation GO:0030888 24 13 0,000 0,01943912 0,03815471 ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,01943912 0,03812317 ! copper ion transport GO:0006825 15 13 0,000 0,01943912 0,03809169 ! filopodium assembly GO:0046847 21 13 0,000 0,01943912 0,03806026 ! lipid localization GO:0010876 25 13 0,000 0,01943912 0,03802889 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,01943912 0,03799756 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,01943912 0,03796629 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,01943912 0,03793506 ! T cell proliferation GO:0042098 24 13 0,000 0,01943912 0,03790389 ! organelle fusion GO:0048284 29 13 0,000 0,01943912 0,03787277 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01943912 0,03784171 ! endocrine pancreas development GO:0031018 19 13 0,000 0,01943912 0,03781069 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,01943912 0,03777972 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,01943912 0,0377488 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,01943912 0,03771794 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,01943912 0,03768712 ! methionine metabolic process GO:0006555 16 13 0,000 0,01943912 0,03765636 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,01943912 0,03762564 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01943912 0,03759498 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,01943912 0,03756436 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,01943912 0,0375338 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,01943912 0,03750328 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,01943912 0,03747282 ! neutral amino acid transport GO:0015804 20 13 0,000 0,01943912 0,0374424 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,01943912 0,03741203 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,01943912 0,03738172 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,01943912 0,03735145 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,01943912 0,03732123 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01943912 0,03729106 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01943912 0,03726094 ! cellular pigmentation GO:0033059 24 13 0,000 0,01943912 0,03723086 ! histone methylation GO:0016571 16 13 0,000 0,01943912 0,03720084 ! oxygen transport GO:0015671 20 13 0,000 0,01943912 0,03717086 ! regulation of axon extension GO:0030516 26 13 0,000 0,01943912 0,03714093 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,01943912 0,03711105 ! detection of bacterium GO:0016045 13 13 0,000 0,01943912 0,03708122 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,01943912 0,03705144 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,01943912 0,0370217 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,01943912 0,03699201 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,01943912 0,03696237 ! actin filament polymerization GO:0030041 18 13 0,000 0,01943912 0,03693278 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,02091921 0,03971304 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,02091921 0,03968129 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,02091921 0,0396496 ! neuron maturation GO:0042551 24 14 0,000 0,02091921 0,03961795 ! regulation of S phase GO:0033261 25 14 0,000 0,02091921 0,03958636 ! regulation of chemokine production GO:0032642 18 14 0,000 0,02091921 0,03955482 ! myotube differentiation GO:0014902 21 14 0,000 0,02091921 0,03952333 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,02091921 0,03949188 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,02091921 0,03946049 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,02091921 0,03942915 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,02091921 0,03939785 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,02091921 0,03936661 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,02091921 0,03933542 ! RNA polyadenylation GO:0043631 21 14 0,000 0,02091921 0,03930427 ! cartilage condensation GO:0001502 22 14 0,000 0,02091921 0,03927318 ! gene silencing by RNA GO:0031047 22 14 0,000 0,02091921 0,03924213 ! response to cAMP GO:0051591 20 14 0,000 0,02091921 0,03921113 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,02091921 0,03918019 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,02091921 0,03914929 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,02091921 0,03911844 ! limbic system development GO:0021761 25 14 0,000 0,02091921 0,03908764 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,02091921 0,03905688 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,02091921 0,03902618 ! palate development GO:0060021 19 14 0,000 0,02091921 0,03899552 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,02091921 0,03896491 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,02091921 0,03893435 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,02091921 0,03890384 ! response to hexose stimulus GO:0009746 22 14 0,000 0,02091921 0,03887337 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! arginine metabolic process GO:0006525 17 14 0,000 0,02091921 0,03884296 ! glutamate metabolic process GO:0006536 21 14 0,000 0,02091921 0,03881259 ! glycine metabolic process GO:0006544 22 14 0,000 0,02091921 0,03878226 ! pituitary gland development GO:0021983 24 14 0,000 0,02091921 0,03875199 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,02091921 0,03872176 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,02091921 0,03869158 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,02091921 0,03866145 ! cytokine metabolic process GO:0042107 18 14 0,000 0,02091921 0,03863136 ! NAD metabolic process GO:0019674 25 14 0,000 0,02091921 0,03860132 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,02091921 0,03857133 ! regulation of heart rate GO:0002027 26 14 0,000 0,02091921 0,03854138 ! exocrine system development GO:0035272 29 14 0,000 0,02091921 0,03851148 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,02091921 0,03848163 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,02091921 0,03845182 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,02091921 0,03842206 ! axon cargo transport GO:0008088 29 14 0,000 0,02091921 0,03839234 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,02091921 0,03836267 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,02091921 0,03833305 ! genitalia development GO:0048806 18 14 0,000 0,02091921 0,03830347 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,02091921 0,03827394 ! autonomic nervous system development GO:0048483 26 14 0,000 0,02091921 0,03824445 ! tissue regeneration GO:0042246 24 14 0,000 0,02091921 0,03821501 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,02091921 0,03818561 ! water homeostasis GO:0030104 23 14 0,000 0,02091921 0,03815626 ! cofactor transport GO:0051181 22 14 0,000 0,02091921 0,03812696 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,02091921 0,0380977 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,02091921 0,03806848 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,02091921 0,03803931 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02091921 0,03801018 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,02091921 0,0379811 ! cell killing GO:0001906 22 14 0,000 0,02091921 0,03795206 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,02091921 0,03792307 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,02091921 0,03789412 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,02091921 0,03786522 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,02091921 0,03783635 ! superoxide anion generation GO:0042554 19 15 0,000 0,02239715 0,04047862 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,02239715 0,04044782 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,02239715 0,04041706 ! inositol metabolic process GO:0006020 21 15 0,000 0,02239715 0,04038634 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,02239715 0,04035568 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,02239715 0,04032506 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,02239715 0,04029449 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,02239715 0,04026396 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02239715 0,04023348 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,02239715 0,04020305 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,02239715 0,04017266 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,02239715 0,04014232 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02239715 0,04011202 ! response to osmotic stress GO:0006970 23 15 0,000 0,02239715 0,04008177 ! vesicle coating GO:0006901 26 15 0,000 0,02239715 0,04005157 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,02239715 0,04002141 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,02239715 0,03999129 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,02239715 0,03996123 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,02239715 0,0399312 ! bone mineralization GO:0030282 17 15 0,000 0,02239715 0,03990122 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,02239715 0,03987129 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,02239715 0,0398414 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,02239715 0,03981156 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,02239715 0,03978176 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,02239715 0,039752 ! regulation of cellular pH GO:0030641 23 15 0,000 0,02239715 0,03972229 ! ribosome assembly GO:0042255 17 15 0,000 0,02239715 0,03969263 ! cerebellum development GO:0021549 19 15 0,000 0,02239715 0,03966301 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,02239715 0,03963343 ! mRNA splice site selection GO:0006376 33 15 0,000 0,02239715 0,0396039 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,02239715 0,03957441 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,02239715 0,03954496 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,02239715 0,03951556 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,02239715 0,0394862 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,02239715 0,03945689 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,02239715 0,03942762 ! muscle maintenance GO:0046716 21 15 0,000 0,02239715 0,03939839 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,02239715 0,03936921 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,02239715 0,03934007 ! intestinal absorption GO:0050892 22 15 0,000 0,02239715 0,03931097 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,02239715 0,03928191 ! dopamine metabolic process GO:0042417 32 15 0,000 0,02239715 0,0392529 ! gas transport GO:0015669 23 15 0,000 0,02239715 0,03922393 ! regulation of RNA stability GO:0043487 31 15 0,000 0,02239715 0,03919501 ! organic cation transport GO:0015695 19 15 0,000 0,02239715 0,03916612 ! heme biosynthetic process GO:0006783 22 15 0,000 0,02239715 0,03913728 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,02239715 0,03910848 ! lymphocyte homeostasis GO:0002260 29 15 0,000 0,02239715 0,03907973 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,02239715 0,03905101 ! cilium assembly GO:0042384 22 15 0,000 0,02239715 0,03902234 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,02239715 0,03899371 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,02239715 0,03896512 ! peptide hormone processing GO:0016486 23 15 0,000 0,02239715 0,03893658 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,02239715 0,03890807 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,02387292 0,04144144 ! bone remodeling GO:0046849 24 16 0,000 0,02387292 0,04141114 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,02387292 0,04138089 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,02387292 0,04135069 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,02387292 0,04132053 ! bile acid metabolic process GO:0008206 23 16 0,000 0,02387292 0,04129041 ! axis specification GO:0009798 26 16 0,000 0,02387292 0,04126034 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,02387292 0,04123031 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,02387292 0,04120032 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02387292 0,04117038 ! centrosome cycle GO:0007098 18 16 0,000 0,02387292 0,04114048 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,02387292 0,04111063 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,02387292 0,04108082 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,02387292 0,04105105 ! cellular response to starvation GO:0009267 26 16 0,000 0,02387292 0,04102132 ! DNA integration GO:0015074 25 16 0,000 0,02387292 0,04099164 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,02387292 0,040962 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,02387292 0,0409324 ! regulation of exocytosis GO:0017157 28 16 0,000 0,02387292 0,04090285 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,02387292 0,04087334 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,02387292 0,04084387 ! regulation of vasodilation GO:0042312 26 16 0,000 0,02387292 0,04081444 ! DNA replication initiation GO:0006270 26 16 0,000 0,02387292 0,04078506 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,02387292 0,04075572 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,02387292 0,04072642 ! neuron recognition GO:0008038 27 16 0,000 0,02387292 0,04069716 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,02387292 0,04066794 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,02387292 0,04063877 ! G1 phase GO:0051318 28 16 0,000 0,02387292 0,04060964 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,02387292 0,04058055 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02387292 0,0405515 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,02387292 0,04052249 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,02387292 0,04049353 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,02387292 0,0404646 ! NADP metabolic process GO:0006739 22 16 0,000 0,02387292 0,04043572 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,02387292 0,04040688 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,02387292 0,04037808 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,02387292 0,04034932 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,02387292 0,0403206 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02387292 0,04029192 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,02387292 0,04026329 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,02387292 0,04023469 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,02387292 0,04020614 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,02387292 0,04017762 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,02387292 0,04014915 ! defense response to virus GO:0051607 28 16 0,000 0,02387292 0,04012071 ! peptide hormone secretion GO:0030072 26 16 0,000 0,02387292 0,04009232 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,02534654 0,04253702 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,02534654 0,04250696 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,02534654 0,04247694 ! zinc ion transport GO:0006829 22 17 0,000 0,02534654 0,04244697 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02534654 0,04241703 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,02534654 0,04238714 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,02534654 0,04235729 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,02534654 0,04232748 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,02534654 0,04229771 ! adult walking behavior GO:0007628 30 17 0,000 0,02534654 0,04226799 ! patterning of blood vessels GO:0001569 27 17 0,000 0,02534654 0,04223831 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,02534654 0,04220867 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,02534654 0,04217907 GO:0042744|hydrogen peroxide catabolic process, ! retinoid metabolic process GO:0001523 22 17 0,000 0,02534654 0,04214951 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,02534654 0,04211999 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,02534654 0,04209052 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,02534654 0,04206108 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02534654 0,04203169 ! protein polyubiquitination GO:0000209 31 17 0,000 0,02534654 0,04200234 ! cerebral cortex development GO:0021987 34 17 0,000 0,02534654 0,04197303 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,02534654 0,04194376 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02534654 0,04191453 ! fructose metabolic process GO:0006000 24 17 0,000 0,02534654 0,04188534 ! membrane budding GO:0006900 30 17 0,000 0,02534654 0,04185619 ! neuromuscular junction development GO:0007528 25 17 0,000 0,02534654 0,04182709 ! L-amino acid transport GO:0015807 27 17 0,000 0,02534654 0,04179802 ! regulation of protein binding GO:0043393 29 17 0,000 0,02534654 0,04176899 ! peptide secretion GO:0002790 30 17 0,000 0,02534654 0,04174001 ! stem cell differentiation GO:0048863 40 17 0,000 0,02534654 0,04171106 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02534654 0,04168215 ! intermediate filament-based process GO:0045103 29 17 0,000 0,02534654 0,04165329 ! protein export from nucleus GO:0006611 26 17 0,000 0,02534654 0,04162446 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,02534654 0,04159568 ! diencephalon development GO:0021536 27 17 0,000 0,02534654 0,04156693 ! oogenesis GO:0048477 25 17 0,000 0,02534654 0,04153822 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,02534654 0,04150956 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,02534654 0,04148093 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02534654 0,04145234 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,02534654 0,04142379 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,02534654 0,04139529 ! steroid catabolic process GO:0006706 24 17 0,000 0,02534654 0,04136682 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,02534654 0,04133838 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,02534654 0,04130999 ! nerve development GO:0021675 20 17 0,000 0,02534654 0,04128164 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,02534654 0,04125333 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,02534654 0,04122505 ! protein secretion GO:0009306 32 18 0,000 0,02681802 0,04358846 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,02681802 0,04355862 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,02681802 0,04352883 ! negative regulation of defense response GO:0031348 21 18 0,000 0,02681802 0,04349908 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,02681802 0,04346937 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,02681802 0,04343969 ! metencephalon development GO:0022037 25 18 0,000 0,02681802 0,04341006 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,02681802 0,04338047 ! hormone secretion GO:0046879 28 18 0,000 0,02681802 0,04335092 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,02681802 0,04332141 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,02681802 0,04329194 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,02681802 0,04326251 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02681802 0,04323312 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,02681802 0,04320377 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,02681802 0,04317446 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02681802 0,04314519 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,02681802 0,04311596 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,02681802 0,04308676 ! glial cell development GO:0021782 31 18 0,000 0,02681802 0,04305761 ! keratinization GO:0031424 19 18 0,000 0,02681802 0,0430285 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,02681802 0,04299943 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,02681802 0,04297039 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,02681802 0,0429414 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,02681802 0,04291244 ! vacuolar transport GO:0007034 26 18 0,000 0,02681802 0,04288352 ! pigmentation during development GO:0048066 35 18 0,000 0,02681802 0,04285465 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,02681802 0,04282581 ! fucose metabolic process GO:0006004 27 18 0,000 0,02681802 0,04279701 ! actin filament bundle formation GO:0051017 30 18 0,000 0,02681802 0,04276825 ! body fluid secretion GO:0007589 27 18 0,000 0,02681802 0,04273952 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,02681802 0,04271084 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,02681802 0,04268219 ! negative regulation of immune response GO:0050777 33 18 0,000 0,02681802 0,04265359 ! heart process GO:0003015 32 18 0,000 0,02681802 0,04262502 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,02681802 0,04259649 ! sensory perception of pain GO:0019233 26 18 0,000 0,02681802 0,04256799 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,02681802 0,04253954 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,02681802 0,04251112 ! somitogenesis GO:0001756 25 18 0,000 0,02681802 0,04248274 ! neural crest cell migration GO:0001755 28 18 0,000 0,02681802 0,0424544 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,02681802 0,0424261 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,02681802 0,04239784 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,02681802 0,04236961 ! synaptogenesis GO:0007416 28 18 0,000 0,02681802 0,04234142 ! cell-cell junction organization GO:0045216 28 18 0,000 0,02681802 0,04231327 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02681802 0,04228515 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,02681802 0,04225707 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,02681802 0,04222903 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,02681802 0,04220103 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,02681802 0,04217306 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,02681802 0,04214513 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,02681802 0,04211724 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,02681802 0,04208939 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,02681802 0,04206157 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,02828734 0,04433676 ! positive regulation of translation GO:0045727 29 19 0,000 0,02828734 0,0443075 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,02828734 0,04427827 ! glycerol metabolic process GO:0006071 22 19 0,000 0,02828734 0,04424908 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,02828734 0,04421993 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,02828734 0,04419082 ! endothelial cell migration GO:0043542 24 19 0,000 0,02828734 0,04416175 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,02828734 0,04413271 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,02828734 0,04410372 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,02828734 0,04407476 ! memory GO:0007613 28 19 0,000 0,02828734 0,04404584 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,02828734 0,04401695 ! pancreas development GO:0031016 27 19 0,000 0,02828734 0,04398811 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,02828734 0,0439593 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,02828734 0,04393053 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,02828734 0,0439018 ! central nervous system neuron development GO:0021954 33 19 0,000 0,02828734 0,04387311 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,02828734 0,04384445 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,02828734 0,04381583 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,02828734 0,04378725 ! heme metabolic process GO:0042168 29 19 0,000 0,02828734 0,04375871 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,02828734 0,0437302 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,02828734 0,04370173 ! response to fungus GO:0009620 21 19 0,000 0,02828734 0,0436733 ! peptide cross-linking GO:0018149 35 19 0,000 0,02828734 0,0436449 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,02828734 0,04361654 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,02828734 0,04358822 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,02828734 0,04355993 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,02828734 0,04353168 ! vitamin transport GO:0051180 26 19 0,000 0,02828734 0,04350347 ! sarcomere organization GO:0045214 26 19 0,000 0,02828734 0,0434753 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,02828734 0,04344716 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,02828734 0,04341905 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,02828734 0,04339099 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,02828734 0,04336296 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,02828734 0,04333496 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,02828734 0,043307 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,02975452 0,04552384 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,02975452 0,0454945 ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,02975452 0,04546521 ! lipid phosphorylation GO:0046834 28 20 0,000 0,02975452 0,04543595 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,02975452 0,04540673 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,02975452 0,04537755 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,02975452 0,04534841 ! response to alkaloid GO:0043279 34 20 0,000 0,02975452 0,0453193 ! sensory perception of taste GO:0050909 26 20 0,000 0,02975452 0,04529023 ! response to retinoic acid GO:0032526 27 20 0,000 0,02975452 0,0452612 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,02975452 0,0452322 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,02975452 0,04520325 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,02975452 0,04517433 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,02975452 0,04514544 ! chromosome condensation GO:0030261 32 20 0,000 0,02975452 0,0451166 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,02975452 0,04508778 ! sex determination GO:0007530 32 20 0,000 0,02975452 0,04505901 ! plasma membrane fusion GO:0045026 24 20 0,000 0,02975452 0,04503028 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,02975452 0,04500158 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,02975452 0,04497291 ! cytolysis GO:0019835 21 20 0,000 0,02975452 0,04494428 ! renal system process GO:0003014 35 20 0,000 0,02975452 0,04491569 ! vasodilation GO:0042311 36 20 0,000 0,02975452 0,04488714 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,02975452 0,04485862 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,02975452 0,04483014 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,02975452 0,04480169 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,02975452 0,04477329 ! hormone transport GO:0009914 30 20 0,000 0,02975452 0,04474491 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,02975452 0,04471657 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,02975452 0,04468827 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,02975452 0,04466001 ! sperm-egg recognition GO:0035036 24 20 0,000 0,02975452 0,04463178 GO:0007339|binding of sperm to zona pellucida, ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,02975452 0,04460358 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,03121956 0,04677021 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,03121956 0,0467407 ! positive regulation of fibroblast proliferation GO:0048146 30 21 0,000 0,03121956 0,04671123 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03121956 0,04668179 ! positive regulation of ossification GO:0045778 34 21 0,000 0,03121956 0,0466524 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 0,000 0,03121956 0,04662304 ! iron ion transport GO:0006826 49 21 0,000 0,03121956 0,04659371 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,03121956 0,04656443 ! microtubule-based transport GO:0010970 41 21 0,000 0,03121956 0,04653518 ! vesicle docking GO:0048278 28 21 0,000 0,03121956 0,04650597 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,03121956 0,04647679 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,03121956 0,04644765 ! response to ethanol GO:0045471 38 21 0,000 0,03121956 0,04641855 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,03121956 0,04638948 ! smooth muscle contraction GO:0006939 39 21 0,000 0,03121956 0,04636045 ! glutamine metabolic process GO:0006541 29 21 0,000 0,03121956 0,04633146 ! response to vitamin A GO:0033189 28 21 0,000 0,03121956 0,0463025 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,03121956 0,04627358 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,03121956 0,0462447 ! apoptotic nuclear changes GO:0030262 31 21 0,000 0,03121956 0,04621585 ! response to starvation GO:0042594 35 21 0,000 0,03121956 0,04618704 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,03121956 0,04615826 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,03121956 0,04612952 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,03121956 0,04610081 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,03121956 0,04607214 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,03121956 0,04604351 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,03121956 0,04601491 ! visual learning GO:0008542 38 21 0,000 0,03121956 0,04598635 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 0,000 0,03121956 0,04595782 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,03121956 0,04592933 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,03121956 0,04590087 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03121956 0,04587245 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,03121956 0,04584406 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,03121956 0,04581571 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03121956 0,0457874 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,03121956 0,04575911 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,03121956 0,04573087 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,03121956 0,04570266 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,03121956 0,04567448 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,03121956 0,04564634 ! embryonic pattern specification GO:0009880 34 22 0,000 0,03268245 0,04775583 ! regulation of cell killing GO:0031341 37 22 0,000 0,03268245 0,04772644 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,03268245 0,04769709 ! gluconeogenesis GO:0006094 26 22 0,000 0,03268245 0,04766777 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,03268245 0,04763849 ! viral genome replication GO:0019079 31 22 0,000 0,03268245 0,04760925 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,03268245 0,04758004 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,03268245 0,04755087 ! protein amino acid acylation GO:0043543 42 22 0,000 0,03268245 0,04752173 ! response to vitamin GO:0033273 31 22 0,000 0,03268245 0,04749263 ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,03268245 0,04746356 ! regeneration GO:0031099 37 22 0,000 0,03268245 0,04743453 ! phototransduction GO:0007602 29 22 0,000 0,03268245 0,04740554 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,03268245 0,04737658 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,03268245 0,04734766 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,03268245 0,04731877 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,03268245 0,04728992 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,03268245 0,0472611 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,03268245 0,04723232 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,03268245 0,04720357 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,03268245 0,04717486 ! pallium development GO:0021543 43 22 0,000 0,03268245 0,04714618 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,03268245 0,04711754 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,03268245 0,04708893 ! platelet activation GO:0030168 33 22 0,000 0,03268245 0,04706035 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,03268245 0,04703182 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,03268245 0,04700331 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,03268245 0,04697484 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,03268245 0,04694641 ! cell-cell recognition GO:0009988 28 22 0,000 0,03268245 0,04691801 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,03268245 0,04688964 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,03268245 0,04686131 ! neural tube closure GO:0001843 35 22 0,000 0,03268245 0,04683301 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,03268245 0,04680475 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,03268245 0,04677652 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,03414322 0,04883777 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,03414322 0,04880835 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,03414322 0,04877896 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,03414322 0,04874961 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,03414322 0,0487203 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,03414322 0,04869102 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,03414322 0,04866178 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,03414322 0,04863257 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,03414322 0,04860339 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,03414322 0,04857425 ! tube lumen formation GO:0035148 37 23 0,000 0,03414322 0,04854515 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,03414322 0,04851608 ! dendrite development GO:0016358 41 23 0,000 0,03414322 0,04848705 ! vasculogenesis GO:0001570 38 23 0,000 0,03414322 0,04845805 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,03414322 0,04842908 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,03414322 0,04840015 ! lysosome organization GO:0007040 41 23 0,000 0,03414322 0,04837126 ! digestive system process GO:0022600 35 23 0,000 0,03414322 0,0483424 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,03414322 0,04831357 ! vesicle targeting GO:0006903 35 23 0,000 0,03414322 0,04828478 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,03414322 0,04825602 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,03414322 0,0482273 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,03414322 0,04819861 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,03414322 0,04816995 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,03414322 0,04814133 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,03414322 0,04811274 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,03414322 0,04808419 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,03414322 0,04805567 ! membrane depolarization GO:0051899 40 23 0,000 0,03414322 0,04802718 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03414322 0,04799873 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,03414322 0,04797031 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,03414322 0,04794193 ! DNA modification GO:0006304 33 23 0,000 0,03414322 0,04791358 ! collagen fibril organization GO:0030199 50 23 0,000 0,03414322 0,04788526 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,03414322 0,04785697 ! cellular response to extracellular stimulus GO:0031668 37 23 0,000 0,03414322 0,04782872 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,03414322 0,04780051 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,03414322 0,04777232 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,03414322 0,04774417 ! positive regulation of B cell activation GO:0050871 36 23 0,000 0,03414322 0,04771605 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03414322 0,04768797 ! collagen catabolic process GO:0030574 29 23 0,000 0,03414322 0,04765992 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,03414322 0,0476319 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,03414322 0,04760391 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,03414322 0,04757596 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,03414322 0,04754804 ! actin filament-based movement GO:0030048 37 23 0,000 0,03414322 0,04752015 ! protein stabilization GO:0050821 34 23 0,000 0,03414322 0,0474923 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,03560185 0,0494922 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,03560185 0,04946322 ! myelination GO:0042552 39 24 0,000 0,03560185 0,04943428 ! initiation of viral infection GO:0019059 47 24 0,000 0,03560185 0,04940537 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,03560185 0,0493765 ! leukocyte adhesion GO:0007159 49 24 0,000 0,03560185 0,04934766 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,03560185 0,04931885 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,03560185 0,04929007 ! visual behavior GO:0007632 42 24 0,000 0,03560185 0,04926133 ! spinal cord development GO:0021510 41 24 0,000 0,03560185 0,04923263 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,03560185 0,04920395 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,03560185 0,04917531 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,03560185 0,04914671 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,03560185 0,04911813 ! cell aging GO:0007569 38 24 0,000 0,03560185 0,04908959 ! osteoblast differentiation GO:0001649 43 24 0,000 0,03560185 0,04906108 ! response to toxin GO:0009636 38 24 0,000 0,03560185 0,04903261 ! primary neural tube formation GO:0014020 37 24 0,000 0,03560185 0,04900417 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,03560185 0,04897576 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,03560185 0,04894739 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,03560185 0,04891904 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,03560185 0,04889073 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,03560185 0,04886246 ! pentose metabolic process GO:0019321 33 24 0,000 0,03560185 0,04883421 ! immunoglobulin production GO:0002377 37 24 0,000 0,03560185 0,048806 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,03560185 0,04877782 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,03560185 0,04874968 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,03560185 0,04872156 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,03560185 0,04869348 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,03560185 0,04866543 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,03560185 0,04863741 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,03560185 0,04860943 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,03560185 0,04858148 ! regulation of fibroblast proliferation GO:0048145 39 25 0,000 0,03705835 0,05053992 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,03705835 0,05051089 ! superoxide metabolic process GO:0006801 33 25 0,000 0,03705835 0,0504819 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,03705835 0,05045293 GO:0050908|detection of light stimulus involved in visual perception, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,03705835 0,05042401 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,03705835 0,05039511 ! vacuole organization GO:0007033 43 25 0,000 0,03705835 0,05036625 ! receptor metabolic process GO:0043112 40 25 0,000 0,03705835 0,05033742 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,03705835 0,05030862 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,03705835 0,05027985 ! regulation of behavior GO:0050795 45 25 0,000 0,03705835 0,05025112 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,03705835 0,05022242 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,03705835 0,05019376 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,03705835 0,05016513 ! negative regulation of phosphorylation GO:0042326 46 25 0,000 0,03705835 0,05013653 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03705835 0,05010796 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,03705835 0,05007942 ! leukocyte homeostasis GO:0001776 40 25 0,000 0,03705835 0,05005092 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,03705835 0,05002245 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,03705835 0,04999401 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,03705835 0,04996561 ! regulation of amine transport GO:0051952 44 25 0,000 0,03705835 0,04993723 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,03851273 0,05186759 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,03851273 0,05183817 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,03851273 0,05180879 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,03851273 0,05177943 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,03851273 0,05175011 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,03851273 0,05172082 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,03851273 0,05169157 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,03851273 0,05166235 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,03851273 0,05163316 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,03851273 0,05160401 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,03851273 0,05157489 ! sperm motility GO:0030317 31 26 0,000 0,03851273 0,0515458 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,03851273 0,05151674 ! male gonad development GO:0008584 39 26 0,000 0,03851273 0,05148772 ! neural crest cell development GO:0014032 44 26 0,000 0,03851273 0,05145873 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,03851273 0,05142977 ! cell fate determination GO:0001709 54 26 0,000 0,03851273 0,05140084 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,03851273 0,05137195 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,03851273 0,05134309 ! detection of visible light GO:0009584 33 26 0,000 0,03851273 0,05131426 ! spermatid development GO:0007286 40 26 0,000 0,03851273 0,05128546 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,03851273 0,0512567 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,03851273 0,05122797 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,03851273 0,05119927 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,03851273 0,0511706 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03996498 0,05307045 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,03996498 0,05304077 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,03996498 0,05301112 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,03996498 0,0529815 ! membrane docking GO:0022406 40 27 0,000 0,03996498 0,05295192 ! circadian rhythm GO:0007623 44 27 0,000 0,03996498 0,05292237 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,03996498 0,05289286 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,03996498 0,05286337 ! autophagy GO:0006914 36 27 0,000 0,03996498 0,05283392 ! myofibril assembly GO:0030239 40 27 0,000 0,03996498 0,0528045 GO:0055002|striated muscle cell development, ! negative regulation of phosphorus metabolic process GO:0010563 51 27 0,000 0,03996498 0,05277512 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,03996498 0,05274577 ! peptide transport GO:0015833 46 27 0,000 0,03996498 0,05271645 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,03996498 0,05268716 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,03996498 0,05265791 ! negative regulation of cell development GO:0010721 67 27 0,000 0,03996498 0,05262868 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,03996498 0,0525995 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,03996498 0,05257034 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,03996498 0,05254121 ! detection of light stimulus GO:0009583 35 27 0,000 0,03996498 0,05251212 ! glutathione metabolic process GO:0006749 35 27 0,000 0,03996498 0,05248306 ! lipid oxidation GO:0034440 39 27 0,000 0,03996498 0,05245403 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,03996498 0,05242504 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,03996498 0,05239607 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,03996498 0,05236714 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,04141511 0,05423733 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,04141511 0,05420742 ! translational initiation GO:0006413 48 28 0,000 0,04141511 0,05417754 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,04141511 0,05414769 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,04141511 0,05411787 ! regulation of pH GO:0006885 40 28 0,000 0,04141511 0,05408808 ! catechol metabolic process GO:0009712 46 28 0,000 0,04141511 0,05405833 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,04141511 0,05402861 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,04141511 0,05399893 ! iron ion homeostasis GO:0055072 49 28 0,000 0,04141511 0,05396928 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,04141511 0,05393965 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,04141511 0,05391007 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,04141511 0,05388051 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,04141511 0,05385099 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,04141511 0,0538215 ! gene silencing GO:0016458 47 28 0,000 0,04141511 0,05379204 ! regulation of coagulation GO:0050818 42 28 0,000 0,04141511 0,05376261 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,04286312 0,05561191 ! phenol metabolic process GO:0018958 47 29 0,000 0,04286312 0,05558152 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,04286312 0,05555117 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,04286312 0,05552084 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,04286312 0,05549055 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,04286312 0,0554603 ! cholesterol transport GO:0030301 48 29 0,000 0,04286312 0,05543007 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,04286312 0,05539988 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,04286312 0,05536973 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,04286312 0,0553396 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,04286312 0,05530951 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,04286312 0,05527945 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,04286312 0,05524942 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,04286312 0,05521943 ! response to ionizing radiation GO:0010212 55 29 0,000 0,04286312 0,05518947 ! muscle cell development GO:0055001 42 29 0,000 0,04286312 0,05515954 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,04286312 0,05512964 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,04286312 0,05509978 ! mesoderm formation GO:0001707 52 29 0,000 0,04286312 0,05506994 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,04286312 0,05504014 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,04286312 0,05501038 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,04286312 0,05498064 ! ensheathment of neurons GO:0007272 48 29 0,000 0,04286312 0,05495094 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,04286312 0,05492127 ! spermatid differentiation GO:0048515 45 29 0,000 0,04286312 0,05489163 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,04286312 0,05486202 ! neural tube formation GO:0001841 46 29 0,000 0,04286312 0,05483245 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,04430902 0,05665156 ! organic anion transport GO:0015711 50 30 0,000 0,04430902 0,05662106 ! acute-phase response GO:0006953 49 30 0,000 0,04430902 0,05659058 ! segmentation GO:0035282 43 30 0,000 0,04430902 0,05656014 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,04430902 0,05652973 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,04430902 0,05649936 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,04430902 0,05646901 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,04430902 0,0564387 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,04430902 0,05640843 ! ceramide metabolic process GO:0006672 47 30 0,000 0,04430902 0,05637818 ! formation of primary germ layer GO:0001704 54 30 0,000 0,04430902 0,05634797 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,04430902 0,05631778 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,04430902 0,05628764 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,04430902 0,05625752 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,04430902 0,05622744 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,04430902 0,05619738 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,04430902 0,05616736 ! response to heat GO:0009408 43 30 0,000 0,04430902 0,05613738 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,04430902 0,05610742 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,04575281 0,05790475 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,04575281 0,05787389 ! post-embryonic development GO:0009791 50 31 0,000 0,04575281 0,05784305 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,04575281 0,05781225 ! regulation of innate immune response GO:0045088 42 31 0,000 0,04575281 0,05778149 ! ovulation cycle process GO:0022602 46 31 0,000 0,04575281 0,05775075 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,04575281 0,05772005 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,04575281 0,05768938 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,04575281 0,05765874 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,04575281 0,05762814 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,04575281 0,05759757 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,04575281 0,05756703 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,04575281 0,05753652 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,04575281 0,05750604 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,04575281 0,0574756 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,04575281 0,05744519 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,04575281 0,05741481 ! tissue homeostasis GO:0001894 45 31 0,000 0,04575281 0,05738447 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,04719449 0,05916139 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,04719449 0,05913016 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,04719449 0,05909895 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,04719449 0,05906778 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,04719449 0,05903664 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,04719449 0,05900554 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,04719449 0,05897447 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,04719449 0,05894343 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,04719449 0,05891242 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,04719449 0,05888145 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,04719449 0,05885051 ! telencephalon development GO:0021537 59 32 0,000 0,04719449 0,0588196 ! ovulation cycle GO:0042698 48 32 0,000 0,04719449 0,05878872 ! cofactor catabolic process GO:0051187 52 32 0,000 0,04719449 0,05875788 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,04719449 0,05872707 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,04719449 0,05869629 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,04719449 0,05866554 ! vesicle localization GO:0051648 50 32 0,000 0,04719449 0,05863482 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,04863406 0,06039174 ! negative regulation of secretion GO:0051048 53 33 0,000 0,04863406 0,06036016 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,04863406 0,06032861 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,04863406 0,06029709 ! sister chromatid segregation GO:0000819 48 33 0,000 0,04863406 0,0602656 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,04863406 0,06023415 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,04863406 0,06020272 ! spindle organization GO:0007051 39 33 0,000 0,04863406 0,06017134 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,04863406 0,06013998 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,04863406 0,06010866 GO:0006639|acylglycerol metabolic process, ! protein targeting to membrane GO:0006612 63 33 0,000 0,04863406 0,06007737 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,04863406 0,06004611 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,04863406 0,06001488 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,04863406 0,05998369 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,04863406 0,05995253 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,04863406 0,0599214 ! cytokine production GO:0001816 49 33 0,000 0,04863406 0,05989031 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,04863406 0,05985924 ! RNA modification GO:0009451 43 33 0,000 0,04863406 0,05982821 ! regulation of B cell activation GO:0050864 55 33 0,000 0,04863406 0,05979721 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,04863406 0,05976625 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,05007153 0,0615009 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,05007153 0,06146908 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,05007153 0,0614373 ! actomyosin structure organization GO:0031032 48 34 0,000 0,05007153 0,06140555 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,05007153 0,06137383 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,05007153 0,06134215 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,05007153 0,0613105 ! positive regulation of cell development GO:0010720 58 34 0,000 0,05007153 0,06127888 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,05007153 0,06124729 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 0,000 0,05007153 0,06121573 ! peripheral nervous system development GO:0007422 58 34 0,000 0,05007153 0,06118421 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,05007153 0,06115272 ! adult locomotory behavior GO:0008344 54 34 0,000 0,05007153 0,06112127 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,05007153 0,06108984 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,0515069 0,06280877 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,0515069 0,06277652 ! collagen metabolic process GO:0032963 47 35 0,000 0,0515069 0,06274429 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,0515069 0,0627121 ! metanephros development GO:0001656 61 35 0,000 0,0515069 0,06267994 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,0515069 0,06264781 ! female gonad development GO:0008585 55 35 0,000 0,0515069 0,06261571 ! lipid homeostasis GO:0055088 63 35 0,000 0,0515069 0,06258365 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,0515069 0,06255163 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,0515069 0,06251963 ! hindbrain development GO:0030902 56 35 0,000 0,0515069 0,06248767 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,0515069 0,06245574 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,0515069 0,06242384 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,0515069 0,06239197 ! cytokinesis GO:0000910 57 35 0,000 0,0515069 0,06236014 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,0515069 0,06232834 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,0515069 0,06229657 ! meiosis I GO:0007127 61 36 0,000 0,05294017 0,06399747 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,05294017 0,06396489 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,05294017 0,06393233 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,05294017 0,06389981 ! spliceosome assembly GO:0000245 65 36 0,000 0,05294017 0,06386733 ! mismatch repair GO:0006298 42 36 0,000 0,05294017 0,06383488 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,05294017 0,06380246 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,05294017 0,06377007 ! regulation of proteolysis GO:0030162 53 36 0,000 0,05294017 0,06373771 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,05294017 0,06370539 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,05294017 0,0636731 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,05294017 0,06364085 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,05294017 0,06360863 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,05437136 0,06529516 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,05437136 0,06526213 ! mammary gland development GO:0030879 73 37 0,000 0,05437136 0,06522913 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,05437136 0,06519617 ! ear morphogenesis GO:0042471 50 37 0,000 0,05437136 0,06516325 ! odontogenesis GO:0042476 60 37 0,000 0,05437136 0,06513035 ! negative regulation of binding GO:0051100 59 37 0,000 0,05437136 0,06509749 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,05437136 0,06506466 ! tissue remodeling GO:0048771 65 37 0,000 0,05437136 0,06503187 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,05437136 0,06499911 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 58 37 0,000 0,05437136 0,06496638 ! natural killer cell activation GO:0030101 45 37 0,000 0,05437136 0,06493368 ! polyol metabolic process GO:0019751 47 37 0,000 0,05437136 0,06490102 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,05437136 0,06486839 ! glucan metabolic process GO:0044042 54 37 0,000 0,05437136 0,06483579 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,05580045 0,06650651 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,05580045 0,06647312 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,05580045 0,06643977 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,05580045 0,06640645 ! feeding behavior GO:0007631 50 38 0,000 0,05580045 0,06637316 ! organic ether metabolic process GO:0018904 51 38 0,000 0,05580045 0,06633991 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,05580045 0,06630669 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,05580045 0,0662735 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,05580045 0,06624035 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,05580045 0,06620723 ! ion transmembrane transport GO:0034220 58 38 0,000 0,05580045 0,06617414 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,05580045 0,06614109 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,05580045 0,06610807 ! neuron migration GO:0001764 59 38 0,000 0,05580045 0,06607508 ! maintenance of protein location GO:0045185 72 38 0,000 0,05580045 0,06604212 ! pigment metabolic process GO:0042440 66 38 0,000 0,05580045 0,0660092 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,05580045 0,06597631 ! mRNA catabolic process GO:0006402 58 39 0,000 0,05722745 0,06762985 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,05722745 0,06759618 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,05722745 0,06756255 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,05722745 0,06752896 ! neural tube development GO:0021915 58 39 0,000 0,05722745 0,06749539 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,05722745 0,06746186 ! regulation of protein stability GO:0031647 58 39 0,000 0,05722745 0,06742837 ! female gamete generation GO:0007292 50 39 0,000 0,05722745 0,0673949 ! aerobic respiration GO:0009060 56 39 0,000 0,05722745 0,06736147 ! positive regulation of leukocyte proliferation GO:0070665 64 39 0,000 0,05722745 0,06732808 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,05722745 0,06729471 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,05865236 0,06893614 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,05865236 0,06890201 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,05865236 0,06886792 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,05865236 0,06883386 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,05865236 0,06879983 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,05865236 0,06876584 ! phagocytosis GO:0006909 65 40 0,000 0,05865236 0,06873188 ! B cell differentiation GO:0030183 70 40 0,000 0,05865236 0,06869796 ! pigmentation GO:0043473 81 40 0,000 0,05865236 0,06866406 ! synapse organization GO:0050808 61 40 0,000 0,05865236 0,06863021 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,0600752 0,07026045 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,0600752 0,07022584 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,0600752 0,07019126 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,0600752 0,07015672 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,0600752 0,07012221 ! cell growth GO:0016049 71 41 0,000 0,0600752 0,07008773 ! maintenance of location in cell GO:0051651 77 41 0,000 0,0600752 0,07005329 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,06149595 0,0716748 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,06149595 0,07163962 ! learning GO:0007612 75 42 0,000 0,06149595 0,07160447 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,06149595 0,07156935 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,06149595 0,07153427 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,06149595 0,07149922 ! endosome transport GO:0016197 74 42 0,000 0,06149595 0,0714642 ! male sex differentiation GO:0046661 62 42 0,000 0,06149595 0,07142922 ! double-strand break repair GO:0006302 75 42 0,000 0,06149595 0,07139428 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,06149595 0,07135936 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,06149595 0,07132449 ! mitochondrial transport GO:0006839 66 43 0,000 0,06291463 0,07293426 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,06291463 0,07289865 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,06291463 0,07286307 ! regulation of tube size GO:0035150 69 43 0,000 0,06291463 0,07282753 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,06291463 0,07279202 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,06291463 0,07275654 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,06291463 0,0727211 ! T cell differentiation GO:0030217 78 43 0,000 0,06291463 0,0726857 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,06291463 0,07265033 ! amino acid activation GO:0043038 61 43 0,000 0,06291463 0,07261499 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,06291463 0,07257969 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,06433124 0,07417786 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,06433124 0,07414183 ! cellular component disassembly GO:0022411 66 44 0,000 0,06433124 0,07410584 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,06433124 0,07406989 ! peptide metabolic process GO:0006518 64 44 0,000 0,06433124 0,07403397 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,06433124 0,07399808 ! inner ear development GO:0048839 66 44 0,000 0,06433124 0,07396223 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,06433124 0,07392641 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,06433124 0,07389063 ! chromatin remodeling GO:0006338 73 44 0,000 0,06433124 0,07385488 ! biopolymer methylation GO:0043414 67 44 0,000 0,06433124 0,07381917 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,06433124 0,07378349 ! JNK cascade GO:0007254 66 44 0,000 0,06433124 0,07374784 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,06433124 0,07371223 ! regulation of cell shape GO:0008360 83 44 0,000 0,06433124 0,07367666 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,06574578 0,07526036 ! positive regulation of binding GO:0051099 67 45 0,000 0,06574578 0,07522407 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,06574578 0,07518782 ! glucose transport GO:0015758 60 45 0,000 0,06574578 0,0751516 ! neuromuscular process GO:0050905 89 45 0,000 0,06574578 0,07511542 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,06574578 0,07507927 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,06574578 0,07504316 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,06574578 0,07500708 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,06715825 0,0765817 ! regulation of translational initiation GO:0006446 70 46 0,000 0,06715825 0,07654492 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,06715825 0,07650817 ! regulation of action potential GO:0001508 80 46 0,000 0,06715825 0,07647146 ! hexose transport GO:0008645 62 46 0,000 0,06715825 0,07643478 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,06715825 0,07639814 ! excretion GO:0007588 72 46 0,000 0,06715825 0,07636153 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,06715825 0,07632496 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,06715825 0,07628843 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,06715825 0,07625192 ! positive regulation of defense response GO:0031349 70 47 0,000 0,06856865 0,07781607 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,06856865 0,07777888 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,06856865 0,07774172 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,06856865 0,07770459 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,069977 0,07926273 ! viral infectious cycle GO:0019058 80 48 0,000 0,069977 0,07922491 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,069977 0,07918713 ! leukocyte migration GO:0050900 76 48 0,000 0,069977 0,07914939 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,069977 0,07911168 ! striated muscle contraction GO:0006941 78 48 0,000 0,069977 0,079074 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,069977 0,07903637 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,069977 0,07899877 ! tRNA processing GO:0008033 56 48 0,000 0,069977 0,0789612 ! cell maturation GO:0048469 69 48 0,000 0,069977 0,07892367 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,069977 0,07888618 ! vesicle organization GO:0016050 87 48 0,000 0,069977 0,07884872 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,069977 0,0788113 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,07138328 0,08035698 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,07138328 0,08031888 ! glycolysis GO:0006096 63 49 0,000 0,07138328 0,08028082 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,07138328 0,08024279 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,07138328 0,08020479 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,07138328 0,08016684 ! response to temperature stimulus GO:0009266 66 49 0,000 0,07138328 0,08012891 ! endocrine system development GO:0035270 86 49 0,000 0,07138328 0,08009103 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,07138328 0,08005318 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,07138328 0,08001536 ! gastrulation GO:0007369 80 49 0,000 0,07138328 0,07997758 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,07138328 0,07993984 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,07138328 0,07990213 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,07138328 0,07986446 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,07138328 0,07982683 ! methylation GO:0032259 74 49 0,000 0,07138328 0,07978922 ! cell redox homeostasis GO:0045454 72 50 0,000 0,07278751 0,08132051 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,07278751 0,08128224 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,07278751 0,08124401 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,07278751 0,08120581 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,07278751 0,08116765 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,07278751 0,08112953 ! regulation of mast cell proliferation GO:0070666 80 50 0,000 0,07278751 0,08109144 ! RNA catabolic process GO:0006401 77 51 0,000 0,07418969 0,08261479 ! chloride transport GO:0006821 78 51 0,000 0,07418969 0,08257604 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,07418969 0,08253733 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,07418969 0,08249865 ! regulation of ossification GO:0030278 82 51 0,000 0,07418969 0,08246001 ! heart morphogenesis GO:0003007 71 51 0,000 0,07418969 0,08242141 ! RNA elongation GO:0006354 67 51 0,000 0,07418969 0,08238284 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,07418969 0,08234431 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,07558981 0,0838591 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,07558981 0,08381992 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,07558981 0,08378077 ! regulation of DNA replication GO:0006275 88 52 0,000 0,07558981 0,08374165 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,07558981 0,08370258 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,07558981 0,08366354 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,07558981 0,08362453 ! proton transport GO:0015992 78 52 0,000 0,07558981 0,08358557 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,07558981 0,08354663 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,07558981 0,08350774 ! transition metal ion transport GO:0000041 88 53 0,000 0,07698789 0,08501269 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,07698789 0,08497315 ! muscle fiber development GO:0048747 80 53 0,000 0,07698789 0,08493364 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,07698789 0,08489418 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,07698789 0,08485475 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,07698789 0,08481535 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,07698789 0,08477599 ! regulation of endocytosis GO:0030100 71 53 0,000 0,07698789 0,08473667 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,07698789 0,08469739 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,07698789 0,08465814 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,07698789 0,08461893 ! regulation of leukocyte proliferation GO:0070663 88 53 0,000 0,07698789 0,08457975 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! maintenance of location GO:0051235 94 53 0,000 0,07698789 0,08454061 ! hydrogen transport GO:0006818 81 54 0,000 0,07838393 0,08603379 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,07838393 0,08599402 ! regulation of mitosis GO:0007088 91 54 0,000 0,07838393 0,08595428 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,07838393 0,08591458 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,07838393 0,08587491 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,07838393 0,08583528 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,07838393 0,08579569 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,07838393 0,08575614 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,07838393 0,08571662 ! germ cell development GO:0007281 82 54 0,000 0,07838393 0,08567713 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,07838393 0,08563769 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,07838393 0,08559828 ! establishment of organelle localization GO:0051656 91 54 0,000 0,07838393 0,0855589 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,07977792 0,08704046 ! ear development GO:0043583 83 55 0,000 0,07977792 0,08700046 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,07977792 0,0869605 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,07977792 0,08692057 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,07977792 0,08688068 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,07977792 0,08684083 ! regulation of actin filament length GO:0030832 88 56 0,000 0,08116988 0,08831551 ! positive regulation of secretion GO:0051047 83 56 0,000 0,08116988 0,08827503 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,08116988 0,08823459 ! DNA catabolic process GO:0006308 71 56 0,000 0,08116988 0,08819419 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,08116988 0,08815383 ! adult behavior GO:0030534 90 56 0,000 0,08116988 0,0881135 ! cartilage development GO:0051216 84 56 0,000 0,08116988 0,08807321 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,0825598 0,0895404 ! mesoderm development GO:0007498 84 57 0,000 0,0825598 0,0894995 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,0825598 0,08945863 ! single fertilization GO:0007338 67 57 0,000 0,0825598 0,0894178 ! regulation of cellular component size GO:0032535 90 58 0,000 0,08394769 0,0908795 ! lipid modification GO:0030258 82 58 0,000 0,08394769 0,09083806 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,08394769 0,09079665 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,08394769 0,09075529 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,08533354 0,09221152 ! viral reproductive process GO:0022415 99 59 0,000 0,08533354 0,09216955 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,08533354 0,09212762 ! chromosome segregation GO:0007059 93 59 0,000 0,08533354 0,09208572 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,08533354 0,09204386 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,08533354 0,09200204 ! glucose catabolic process GO:0006007 78 60 0,000 0,08671738 0,09345156 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,08671738 0,09340914 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,08671738 0,09336676 ! kidney development GO:0001822 101 60 0,000 0,08671738 0,09332441 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,08671738 0,09328211 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,08809918 0,09472558 ! carbohydrate transport GO:0008643 83 61 0,000 0,08809918 0,09468268 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,08809918 0,09463982 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,08947897 0,09607855 ! amino acid transport GO:0006865 97 62 0,000 0,08947897 0,09603509 ! activation of MAPK activity GO:0000187 95 62 0,000 0,08947897 0,09599168 ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,08947897 0,0959483 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,08947897 0,09590497 ! detection of external stimulus GO:0009581 78 62 0,000 0,08947897 0,09586167 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,08947897 0,09581841 ! secondary metabolic process GO:0019748 95 62 0,000 0,08947897 0,09577519 ! gonad development GO:0008406 91 62 0,000 0,08947897 0,09573201 ! exocytosis GO:0006887 91 63 0,000 0,09085674 0,09716225 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,09085674 0,09711849 ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,09085674 0,09707476 ! regulation of heart contraction GO:0008016 104 63 0,000 0,09085674 0,09703107 ! actin filament organization GO:0007015 107 64 0,000 0,09223249 0,09845601 ! fertilization GO:0009566 79 64 0,000 0,09223249 0,09841174 ! viral reproduction GO:0016032 104 64 0,000 0,09223249 0,09836751 ! amine catabolic process GO:0009310 100 65 0,000 0,09360623 0,09978777 ! negative regulation of cell growth GO:0030308 123 65 0,000 0,09360623 0,09974297 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,09360623 0,0996982 ! regulation of lipase activity GO:0060191 117 65 0,000 0,09360623 0,09965347 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,09360623 0,09960878 ! organelle localization GO:0051640 105 65 0,000 0,09360623 0,09956413 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,09497796 0,10097791 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,09497796 0,10093269 ! sensory perception of smell GO:0007608 81 66 0,000 0,09497796 0,10088751 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,09497796 0,10084237 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,09497796 0,10079727 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,09497796 0,10075221 ! B cell activation GO:0042113 119 66 0,000 0,09497796 0,10070719 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,09497796 0,10066222 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,09634768 0,10206833 ! negative regulation of cell size GO:0045792 125 67 0,000 0,09634768 0,10202278 ! neurotransmitter transport GO:0006836 92 67 0,000 0,09634768 0,10197728 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,09634768 0,10193181 ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,09634768 0,10188639 ! extracellular matrix organization GO:0030198 117 67 0,000 0,09634768 0,101841 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,09634768 0,10179566 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! meiosis GO:0007126 110 68 0,000 0,0977154 0,10319477 GO:0051327|M phase of meiotic cell cycle, ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,0977154 0,10314887 ! defense response to bacterium GO:0042742 79 68 0,000 0,0977154 0,103103 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,0977154 0,10305718 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,0977154 0,1030114 ! activation of immune response GO:0002253 93 68 0,000 0,0977154 0,10296565 ! urogenital system development GO:0001655 114 69 0,000 0,09908112 0,10435841 ! meiotic cell cycle GO:0051321 111 69 0,000 0,09908112 0,10431211 ! hexose catabolic process GO:0019320 95 70 0,000 0,10044484 0,10570094 ! adaptive immune response GO:0002250 102 70 0,000 0,10044484 0,10565408 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,10180657 0,10703898 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,10180657 0,10699158 ! axon guidance GO:0007411 116 71 0,000 0,10180657 0,10694422 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,10180657 0,1068969 ! response to drug GO:0042493 115 72 0,000 0,1031663 0,1082767 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,1031663 0,10822884 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,1031663 0,10818101 ! rhythmic process GO:0048511 113 72 0,000 0,1031663 0,10813323 ! regulation of immune effector process GO:0002697 121 72 0,000 0,1031663 0,10808549 ! learning or memory GO:0007611 132 73 0,000 0,10452404 0,10945964 ! humoral immune response GO:0006959 93 73 0,000 0,10452404 0,10941136 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,10452404 0,10936312 ! acute inflammatory response GO:0002526 107 74 0,000 0,1058798 0,11073281 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,1058798 0,11068403 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,1058798 0,11063529 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,1058798 0,1105866 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,1058798 0,11053795 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,10723357 0,11190205 ! inorganic anion transport GO:0015698 109 75 0,000 0,10723357 0,11185286 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,10723357 0,11180371 ! regulation of catabolic process GO:0009894 114 75 0,000 0,10723357 0,11175461 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,10858535 0,11311372 ! phosphoinositide-mediated signaling GO:0048015 122 76 0,000 0,10858535 0,11306408 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,10993516 0,11441936 ! response to nutrient GO:0007584 114 77 0,000 0,10993516 0,1143692 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,10993516 0,11431908 ! regulation of blood pressure GO:0008217 119 78 0,000 0,111283 0,11566998 ! muscle cell differentiation GO:0042692 117 78 0,000 0,111283 0,11561933 ! negative regulation of growth GO:0045926 140 78 0,000 0,111283 0,11556873 ! amine transport GO:0015837 115 78 0,000 0,111283 0,11551818 ! antigen processing and presentation GO:0019882 114 78 0,000 0,111283 0,11546767 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,11262886 0,11681306 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,11397275 0,11815524 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,11397275 0,11810364 ! regulation of DNA binding GO:0051101 130 80 0,000 0,11397275 0,11805209 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,11397275 0,11800058 ! protein ubiquitination GO:0016567 135 80 0,000 0,11397275 0,11794912 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,11397275 0,11789771 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,11397275 0,11784633 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,11397275 0,11779501 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,11397275 0,11774373 ! blood coagulation GO:0007596 129 81 0,000 0,11531467 0,11907821 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,11531467 0,11902641 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,11531467 0,11897466 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,11531467 0,11892296 ! response to hypoxia GO:0001666 155 81 0,000 0,11531467 0,1188713 ! regulation of protein transport GO:0051223 123 81 0,000 0,11531467 0,11881968 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,11665463 0,1201482 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,11665463 0,12009607 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,11665463 0,12004399 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,11665463 0,11999196 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,11799263 0,12131565 ! response to oxygen levels GO:0070482 160 83 0,000 0,11799263 0,12126311 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,11799263 0,12121061 ! regulation of lyase activity GO:0051339 147 83 0,000 0,11799263 0,12115816 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,11799263 0,12110576 ! positive regulation of lymphocyte activation GO:0051251 134 83 0,000 0,11799263 0,1210534 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,11932867 0,12237119 ! digestion GO:0007586 111 84 0,000 0,11932867 0,12231833 ! regulation of neurological system process GO:0031644 133 84 0,000 0,11932867 0,12226551 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,11932867 0,12221274 ! cellular respiration GO:0045333 119 85 0,000 0,12066275 0,12352576 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,12066275 0,12347249 ! T cell activation GO:0042110 154 85 0,000 0,12066275 0,12341927 ! sex differentiation GO:0007548 126 85 0,000 0,12066275 0,12336609 ! protein import into nucleus GO:0006606 145 85 0,000 0,12066275 0,12331296 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,12066275 0,12325988 ! alcohol catabolic process GO:0046164 119 86 0,000 0,12199488 0,12456706 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,12199488 0,12451348 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,12332505 0,125817 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,12332505 0,12576293 ! regulation of defense response GO:0031347 135 87 0,000 0,12332505 0,12570891 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,12332505 0,12565494 ! tRNA metabolic process GO:0006399 110 87 0,000 0,12332505 0,12560101 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,12332505 0,12554712 ! gland development GO:0048732 170 87 0,000 0,12332505 0,12549329 ! vitamin metabolic process GO:0006766 117 87 0,000 0,12332505 0,1254395 ! nucleosome assembly GO:0006334 113 89 0,000 0,12597956 0,12808462 GO:0031497|chromatin assembly, ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,1273039 0,12937566 ! microtubule cytoskeleton organization GO:0000226 133 90 0,000 0,1273039 0,12932027 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,1273039 0,12926494 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,1273039 0,12920965 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,1273039 0,12915441 ! nuclear import GO:0051170 153 90 0,000 0,1273039 0,12909921 ! regulation of protein localization GO:0032880 141 90 0,000 0,1273039 0,12904407 ! positive regulation of cell activation GO:0050867 146 90 0,000 0,1273039 0,12898897 GO:0002696|positive regulation of leukocyte activation, ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,1286263 0,13027325 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,1286263 0,13021767 ! protein localization in nucleus GO:0034504 161 92 0,000 0,12994677 0,13149837 ! sterol metabolic process GO:0016125 136 92 0,000 0,12994677 0,13144232 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,1312653 0,13271945 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cell cycle arrest GO:0007050 171 93 0,000 0,1312653 0,13266292 ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,1312653 0,13260645 ! rRNA processing GO:0006364 124 93 0,000 0,1312653 0,13255002 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,1312653 0,13249364 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,1312653 0,13243731 ! leukocyte differentiation GO:0002521 165 94 0,000 0,13258189 0,13370881 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,13258189 0,13365201 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,13258189 0,13359526 ! rRNA metabolic process GO:0016072 125 94 0,000 0,13258189 0,13353855 ! hormone metabolic process GO:0042445 135 94 0,000 0,13258189 0,1334819 ! protein processing GO:0016485 127 94 0,000 0,13258189 0,13342529 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,13389656 0,1346912 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,13389656 0,13463413 ! ATP metabolic process GO:0046034 150 96 0,000 0,1352093 0,13589652 ! nucleosome organization GO:0034728 126 96 0,000 0,1352093 0,13583898 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,1352093 0,1357815 ! reproductive developmental process GO:0003006 149 97 0,000 0,13652012 0,13703987 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,13782902 0,13829525 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,13782902 0,1382368 ! regulation of T cell activation GO:0050863 155 98 0,000 0,13782902 0,1381784 ! regulation of binding GO:0051098 164 99 0,000 0,139136 0,13942978 ! electron transport chain GO:0022900 135 99 0,000 0,139136 0,13937093 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,139136 0,13931212 ! positive regulation of immune response GO:0050778 143 99 0,000 0,139136 0,13925336 ! sulfur metabolic process GO:0006790 136 99 0,000 0,139136 0,13919466 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,14044106 0,14044106