pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/3741-4-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! hair follicle maturation GO:0048820 5 5 1,000 1,897E-05 0,0349658 ! regulation of myoblast differentiation GO:0045661 5 5 1,000 1,897E-05 0,0174829 ! positive regulation of epidermis development GO:0045684 5 5 1,000 1,897E-05 0,01165527 ! regulation of epidermal cell differentiation GO:0045604 5 5 1,000 1,897E-05 8,741E-03 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 1,897E-05 6,993E-03 GO:0007439|ectodermal gut development, ! positive regulation of cell growth GO:0030307 6 6 1,000 2,844E-05 8,735E-03 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 2,844E-05 7,487E-03 ! regulation of Rho GTPase activity GO:0032319 6 6 1,000 2,844E-05 6,551E-03 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 2,844E-05 5,823E-03 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 3,978E-05 7,331E-03 ! hair follicle morphogenesis GO:0031069 7 7 1,000 3,978E-05 6,665E-03 ! keratinocyte proliferation GO:0043616 7 7 1,000 3,978E-05 6,11E-03 ! negative regulation of muscle cell differentiation GO:0051148 7 7 1,000 3,978E-05 5,64E-03 ! digestive system development GO:0055123 7 7 1,000 3,978E-05 5,237E-03 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! endoderm development GO:0007492 7 7 1,000 3,978E-05 4,888E-03 ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 3,978E-05 4,582E-03 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 5,3E-05 5,746E-03 ! embryonic hindlimb morphogenesis GO:0035116 8 8 1,000 5,3E-05 5,426E-03 ! regulation of stress fiber formation GO:0051492 9 8 1,000 5,3E-05 5,141E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 5,3E-05 4,884E-03 ! positive regulation of cell size GO:0045793 9 9 1,000 6,809E-05 5,976E-03 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 6,809E-05 5,704E-03 ! negative regulation of caspase activity GO:0043154 9 9 1,000 6,809E-05 5,456E-03 ! regulation of dephosphorylation GO:0035303 9 9 1,000 6,809E-05 5,229E-03 ! regulation of actin filament bundle formation GO:0032231 10 9 1,000 6,809E-05 5,019E-03 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 8,504E-05 6,028E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 8,504E-05 5,805E-03 ! epidermis morphogenesis GO:0048730 10 10 1,000 8,504E-05 5,598E-03 ! histone deacetylation GO:0016575 10 10 1,000 8,504E-05 5,405E-03 ! regulation of epidermis development GO:0045682 10 10 1,000 8,504E-05 5,225E-03 ! negative regulation of neuron differentiation GO:0045665 10 10 1,000 8,504E-05 5,056E-03 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 8,504E-05 4,898E-03 ! gut development GO:0048565 10 10 1,000 8,504E-05 4,75E-03 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 9,214E-05 4,994E-03 ! determination of bilateral symmetry GO:0009855 11 11 1,000 1,039E-04 5,469E-03 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! skin development GO:0043588 11 11 1,000 1,039E-04 5,317E-03 ! hindlimb morphogenesis GO:0035137 12 12 1,000 1,245E-04 6,203E-03 ! regulation of muscle cell differentiation GO:0051147 13 12 1,000 1,245E-04 6,04E-03 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 1,245E-04 5,885E-03 ! regulation of chromosome organization GO:0033044 12 12 1,000 1,245E-04 5,738E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 1,245E-04 5,598E-03 ! negative regulation of translation GO:0017148 12 12 1,000 1,245E-04 5,465E-03 ! negative regulation of protein modification process GO:0031400 13 13 1,000 1,471E-04 6,303E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 1,471E-04 6,16E-03 GO:0001952|regulation of cell-matrix adhesion, ! neuron fate commitment GO:0048663 14 14 1,000 1,714E-04 7,022E-03 ! protein amino acid deacetylation GO:0006476 14 14 1,000 1,714E-04 6,869E-03 ! hair cycle GO:0042633 14 14 1,000 1,714E-04 6,723E-03 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! positive regulation of mitosis GO:0045840 16 16 1,000 2,257E-04 8,667E-03 GO:0051785|positive regulation of nuclear division, ! cell fate specification GO:0001708 16 16 1,000 2,257E-04 8,49E-03 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 2,556E-04 9,423E-03 ! epidermis development GO:0008544 94 94 2,000 2,765E-04 9,993E-03 ! meiosis I GO:0007127 18 18 1,000 2,874E-04 0,01018478 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 2,874E-04 9,993E-03 ! glial cell differentiation GO:0010001 19 19 1,000 3,209E-04 0,01095289 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 3,209E-04 0,01075375 ! ectoderm development GO:0007398 99 99 2,000 3,223E-04 0,01060807 ! regulation of muscle development GO:0048634 21 20 1,000 3,563E-04 0,01152042 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 3,935E-04 0,01250385 ! Notch signaling pathway GO:0007219 22 21 1,000 3,935E-04 0,01229192 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 3,935E-04 0,01208706 ! RNA export from nucleus GO:0006405 22 22 1,000 4,325E-04 0,01306766 ! sister chromatid segregation GO:0000819 22 22 1,000 4,325E-04 0,01285689 ! spindle organization GO:0007051 22 22 1,000 4,325E-04 0,01265281 ! cytokinesis GO:0000910 23 22 1,000 4,325E-04 0,01245511 ! positive regulation of growth GO:0045927 23 23 1,000 4,733E-04 0,01342103 ! gliogenesis GO:0042063 24 24 1,000 5,16E-04 0,0144081 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 6,066E-04 0,01668692 ! response to insulin stimulus GO:0032868 28 26 1,000 6,066E-04 0,01644152 ! mesenchymal cell development GO:0014031 29 27 1,000 6,547E-04 0,01748593 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! keratinocyte differentiation GO:0030216 28 28 1,000 7,045E-04 0,01854759 ! histone modification GO:0016570 28 28 1,000 7,045E-04 0,01828635 ! developmental growth GO:0048589 28 28 1,000 7,045E-04 0,01803238 ! positive regulation of cell cycle GO:0045787 29 29 1,000 7,561E-04 0,01908797 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 7,561E-04 0,01883003 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 7,561E-04 0,01857896 ! covalent chromatin modification GO:0016569 29 29 1,000 7,561E-04 0,0183345 ! establishment of organelle localization GO:0051656 31 30 1,000 8,094E-04 0,01937395 ! aging GO:0007568 32 31 1,000 8,646E-04 0,02042871 ! epidermal cell differentiation GO:0009913 31 31 1,000 8,646E-04 0,02017012 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 9,215E-04 0,02122938 ! nuclear export GO:0051168 32 32 1,000 9,215E-04 0,02096729 ! regulation of neuron differentiation GO:0045664 34 33 1,000 9,802E-04 0,02203072 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 1,041E-03 0,02310768 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 1,103E-03 0,0241976 ! regulation of mitosis GO:0007088 37 36 1,000 1,167E-03 0,02529993 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 1,000 1,167E-03 0,02500574 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of organelle organization GO:0010638 36 36 1,000 1,167E-03 0,02471832 ! meiosis GO:0007126 37 37 1,000 1,233E-03 0,02581381 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 1,233E-03 0,02552377 ! lung development GO:0030324 38 37 1,000 1,233E-03 0,02524017 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 1,233E-03 0,02496281 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 1,233E-03 0,02469147 ! negative regulation of kinase activity GO:0033673 38 38 1,000 1,3E-03 0,02576297 ! chromosome segregation GO:0007059 38 38 1,000 1,3E-03 0,0254889 ! meiotic cell cycle GO:0051321 38 38 1,000 1,3E-03 0,02522059 ! respiratory tube development GO:0030323 40 39 1,000 1,369E-03 0,02628655 ! respiratory system development GO:0060541 40 39 1,000 1,369E-03 0,02601555 ! developmental maturation GO:0021700 39 39 1,000 1,369E-03 0,02575009 ! limb development GO:0060173 39 39 1,000 1,369E-03 0,02548998 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! negative regulation of transferase activity GO:0051348 40 40 1,000 1,44E-03 0,02654264 ! organelle localization GO:0051640 41 40 1,000 1,44E-03 0,02627984 ! regulation of caspase activity GO:0043281 41 41 1,000 1,513E-03 0,02733545 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 1,513E-03 0,02707005 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 1,587E-03 0,02812841 ! forebrain development GO:0030900 43 42 1,000 1,587E-03 0,02786052 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 1,587E-03 0,02759769 ! mitochondrion organization GO:0007005 44 43 1,000 1,663E-03 0,02865117 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 1,741E-03 0,02971452 ! negative regulation of organelle organization GO:0010639 45 44 1,000 1,741E-03 0,02944191 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 1,821E-03 0,03050751 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 1,821E-03 0,03023267 ! regulation of actin filament-based process GO:0032970 47 46 1,000 1,902E-03 0,03130038 ! tube morphogenesis GO:0035239 47 46 1,000 1,902E-03 0,03102338 ! regulation of peptidase activity GO:0052547 46 46 1,000 1,902E-03 0,03075125 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 1,902E-03 0,03048385 ! positive regulation of ligase activity GO:0051351 47 46 1,000 1,902E-03 0,03022105 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 2,07E-03 0,03260441 ! regulation of cell cycle process GO:0010564 50 48 1,000 2,07E-03 0,0323281 ! regulation of ligase activity GO:0051340 50 49 1,000 2,156E-03 0,03339461 ! RNA transport GO:0050658 50 50 1,000 2,244E-03 0,03446941 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! regulation of neurogenesis GO:0050767 51 50 1,000 2,244E-03 0,03418454 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 2,244E-03 0,03390434 ! RNA localization GO:0006403 52 52 1,000 2,426E-03 0,03634488 ! cell fate commitment GO:0045165 52 52 1,000 2,426E-03 0,03605178 ! regulation of GTPase activity GO:0043087 53 52 1,000 2,426E-03 0,03576336 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 2,519E-03 0,03684228 ! response to virus GO:0009615 54 54 1,000 2,614E-03 0,03792858 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 2,614E-03 0,03763227 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 2,71E-03 0,03871956 ! regulation of cell adhesion GO:0030155 56 55 1,000 2,71E-03 0,03842171 ! regulation of nervous system development GO:0051960 57 56 1,000 2,808E-03 0,0395099 ! regulation of cell development GO:0060284 60 59 1,000 3,113E-03 0,04346316 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 3,218E-03 0,04458921 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 3,324E-03 0,04572117 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! axonogenesis GO:0007409 66 62 1,000 3,432E-03 0,04685886 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 3,432E-03 0,04651431 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 3,542E-03 0,04765171 ! angiogenesis GO:0001525 65 64 1,000 3,654E-03 0,04879453 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 3,654E-03 0,04844349 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 3,881E-03 0,05109575 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 3,998E-03 0,05225381 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! negative regulation of cell differentiation GO:0045596 68 67 1,000 3,998E-03 0,05188583 ! regulation of cell size GO:0008361 68 68 1,000 4,116E-03 0,0530431 ! regulation of translation GO:0006417 69 69 1,000 4,235E-03 0,05420503 ! regionalization GO:0003002 70 69 1,000 4,235E-03 0,05383121 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 4,235E-03 0,0534625 ! cell part morphogenesis GO:0032990 75 70 1,000 4,356E-03 0,05461812 ! growth GO:0040007 70 70 1,000 4,356E-03 0,05424908 ! ribosome biogenesis GO:0042254 71 71 1,000 4,479E-03 0,05540385 ! negative regulation of signal transduction GO:0009968 71 71 1,000 4,479E-03 0,05503449 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 4,604E-03 0,05618839 ! negative regulation of cell communication GO:0010648 76 76 1,000 5,117E-03 0,06204623 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 5,25E-03 0,06323534 ! regulation of protein modification process GO:0031399 79 78 1,000 5,384E-03 0,06442797 ! nuclear transport GO:0051169 79 79 1,000 5,519E-03 0,06562399 GO:0006913|nucleocytoplasmic transport, ! neuron projection development GO:0031175 85 80 1,000 5,656E-03 0,06682331 ! tube development GO:0035295 83 81 1,000 5,795E-03 0,0680258 ! blood vessel morphogenesis GO:0048514 84 83 1,000 6,077E-03 0,07088574 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 6,365E-03 0,07378205 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 6,512E-03 0,07500839 ! heart development GO:0007507 90 87 1,000 6,66E-03 0,07623723 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 7,113E-03 0,08092472 ! brain development GO:0007420 91 90 1,000 7,113E-03 0,08042825 ! rRNA transcription GO:0009303 5 5 0,000 7,248E-03 0,08145664 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 7,248E-03 0,08096296 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 7,248E-03 0,08047523 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 7,248E-03 0,07999335 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 7,248E-03 0,0795172 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 7,248E-03 0,07904668 ! reproductive cellular process GO:0048610 5 5 0,000 7,248E-03 0,0785817 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 7,248E-03 0,07812216 ! negative regulation of blood pressure GO:0045776 6 5 0,000 7,248E-03 0,07766796 ! prostate gland development GO:0030850 5 5 0,000 7,248E-03 0,07721901 ! metencephalon development GO:0022037 5 5 0,000 7,248E-03 0,07677522 ! water transport GO:0006833 5 5 0,000 7,248E-03 0,07633651 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 7,248E-03 0,07590278 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 7,248E-03 0,07547395 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 7,248E-03 0,07504994 ! glycerol metabolic process GO:0006071 5 5 0,000 7,248E-03 0,07463066 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 7,248E-03 0,07421605 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 7,248E-03 0,07380602 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 7,248E-03 0,07340049 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 7,248E-03 0,07299939 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 7,248E-03 0,07260266 ! filopodium assembly GO:0046847 7 5 0,000 7,248E-03 0,07221021 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 7,248E-03 0,07182198 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 7,248E-03 0,07143791 ! GTP metabolic process GO:0046039 5 5 0,000 7,248E-03 0,07105792 ! establishment of tissue polarity GO:0007164 5 5 0,000 7,248E-03 0,07068195 ! mRNA stabilization GO:0048255 5 5 0,000 7,248E-03 0,07030994 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 7,248E-03 0,06994183 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 7,248E-03 0,06957755 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 7,248E-03 0,06921704 ! social behavior GO:0035176 5 5 0,000 7,248E-03 0,06886025 ! macrophage chemotaxis GO:0048246 6 5 0,000 7,248E-03 0,06850712 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 7,248E-03 0,0681576 ! memory GO:0007613 5 5 0,000 7,248E-03 0,06781162 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 7,248E-03 0,06746914 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 7,248E-03 0,06713009 ! membrane hyperpolarization GO:0060081 5 5 0,000 7,248E-03 0,06679444 ! response to lipid GO:0033993 5 5 0,000 7,248E-03 0,06646213 ! erythrocyte maturation GO:0043249 5 5 0,000 7,248E-03 0,06613311 ! hippocampus development GO:0021766 6 5 0,000 7,248E-03 0,06580733 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 7,248E-03 0,06548475 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 7,248E-03 0,06516531 ! middle ear morphogenesis GO:0042474 5 5 0,000 7,248E-03 0,06484897 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 7,248E-03 0,06453569 ! mechanosensory behavior GO:0007638 5 5 0,000 7,248E-03 0,06422543 ! heart looping GO:0001947 5 5 0,000 7,248E-03 0,06391813 ! negative regulation of endocytosis GO:0045806 5 5 0,000 7,248E-03 0,06361376 ! response to interferon-gamma GO:0034341 5 5 0,000 7,248E-03 0,06331227 ! pseudouridine synthesis GO:0001522 5 5 0,000 7,248E-03 0,06301363 ! endocrine pancreas development GO:0031018 5 5 0,000 7,248E-03 0,06271779 ! pH reduction GO:0045851 5 5 0,000 7,248E-03 0,06242471 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 7,248E-03 0,06213437 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 7,248E-03 0,06184671 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 7,248E-03 0,0615617 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 7,248E-03 0,06127931 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 7,248E-03 0,06099949 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 7,248E-03 0,06072222 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 7,248E-03 0,06044746 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 7,248E-03 0,06017517 ! adrenal gland development GO:0030325 5 5 0,000 7,248E-03 0,05990533 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 7,248E-03 0,0596379 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 7,248E-03 0,05937284 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 7,248E-03 0,05911013 ! astrocyte differentiation GO:0048708 5 5 0,000 7,248E-03 0,05884973 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 7,248E-03 0,05859162 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 7,248E-03 0,05833576 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 7,248E-03 0,05808213 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 7,248E-03 0,05783069 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 7,248E-03 0,05758142 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 7,248E-03 0,05733429 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 7,248E-03 0,05708927 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 7,248E-03 0,05684634 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 7,248E-03 0,05660546 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 7,248E-03 0,05636662 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 7,248E-03 0,05612979 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 7,248E-03 0,05589493 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 7,248E-03 0,05566204 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 7,248E-03 0,05543107 ! response to ATP GO:0033198 5 5 0,000 7,248E-03 0,05520202 ! regulation of type I interferon production GO:0032479 5 5 0,000 7,248E-03 0,05497485 ! regulation of appetite GO:0032098 5 5 0,000 7,248E-03 0,05474954 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 7,248E-03 0,05452608 ! paraxial mesoderm development GO:0048339 5 5 0,000 7,248E-03 0,05430443 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 7,248E-03 0,05408457 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 7,248E-03 0,05386649 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 7,248E-03 0,05365016 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 7,248E-03 0,05343556 ! receptor clustering GO:0043113 5 5 0,000 7,248E-03 0,05322266 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 7,248E-03 0,05301146 ! fear response GO:0042596 5 5 0,000 7,248E-03 0,05280193 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 7,248E-03 0,05259405 ! lens development in camera-type eye GO:0002088 5 5 0,000 7,248E-03 0,0523878 ! retinol metabolic process GO:0042572 5 5 0,000 7,248E-03 0,05218316 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 7,248E-03 0,05198011 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 7,248E-03 0,05177864 ! positive regulation of exocytosis GO:0045921 6 5 0,000 7,248E-03 0,05157872 ! parturition GO:0007567 5 5 0,000 7,248E-03 0,05138034 ! cellular glucose homeostasis GO:0001678 5 5 0,000 7,248E-03 0,05118348 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 7,248E-03 0,05098813 ! Schwann cell differentiation GO:0014037 5 5 0,000 7,248E-03 0,05079425 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 7,248E-03 0,05060185 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 7,248E-03 0,0504109 ! protein heterooligomerization GO:0051291 5 5 0,000 7,248E-03 0,05022139 ! regulation of gliogenesis GO:0014013 5 5 0,000 7,248E-03 0,05003329 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 7,248E-03 0,0498466 ! response to UV-B GO:0010224 5 5 0,000 7,248E-03 0,0496613 ! oligodendrocyte development GO:0014003 5 5 0,000 7,248E-03 0,04947737 ! hyaluronan metabolic process GO:0030212 5 5 0,000 7,248E-03 0,04929479 ! activated T cell proliferation GO:0050798 5 5 0,000 7,248E-03 0,04911356 ! interaction with symbiont GO:0051702 5 5 0,000 7,248E-03 0,04893366 ! cellular extravasation GO:0045123 5 5 0,000 7,248E-03 0,04875507 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 7,248E-03 0,04857778 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 7,248E-03 0,04840177 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 7,248E-03 0,04822704 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 7,248E-03 0,04805356 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 7,248E-03 0,04788132 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 7,248E-03 0,04771032 ! response to amine stimulus GO:0014075 5 5 0,000 7,248E-03 0,04754053 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 7,248E-03 0,04737195 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 7,248E-03 0,04720455 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 7,248E-03 0,04703834 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 7,248E-03 0,04687329 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 7,248E-03 0,0467094 ! neuron recognition GO:0008038 5 5 0,000 7,248E-03 0,04654665 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 7,248E-03 0,04638503 ! decidualization GO:0046697 5 5 0,000 7,248E-03 0,04622453 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 7,248E-03 0,04606513 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 7,248E-03 0,04590683 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 7,248E-03 0,04574962 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 7,248E-03 0,04559348 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 7,248E-03 0,0454384 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 7,248E-03 0,04528437 ! postreplication repair GO:0006301 5 5 0,000 7,248E-03 0,04513138 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 7,248E-03 0,04497942 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 7,248E-03 0,04482849 ! histone methylation GO:0016571 5 5 0,000 7,248E-03 0,04467856 ! DNA methylation GO:0006306 5 5 0,000 7,248E-03 0,04452963 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 7,248E-03 0,04438169 ! T cell lineage commitment GO:0002360 5 5 0,000 7,248E-03 0,04423473 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 7,248E-03 0,04408874 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 7,248E-03 0,04394371 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 7,248E-03 0,04379964 ! intracellular cholesterol transport GO:0032367 5 5 0,000 7,248E-03 0,0436565 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 7,248E-03 0,0435143 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 7,248E-03 0,04337302 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 7,248E-03 0,04323265 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 7,248E-03 0,04309319 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 7,248E-03 0,04295463 ! sterol catabolic process GO:0016127 5 5 0,000 7,248E-03 0,04281695 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 7,248E-03 0,04268016 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 7,248E-03 0,04254423 ! detection of biotic stimulus GO:0009595 5 5 0,000 7,248E-03 0,04240917 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 7,248E-03 0,04227496 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 7,248E-03 0,04214161 ! zymogen activation GO:0031638 5 5 0,000 7,248E-03 0,04200908 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 7,248E-03 0,04187739 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 7,248E-03 0,04174653 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 7,248E-03 0,04161648 ! peptidyl-lysine modification GO:0018205 5 5 0,000 7,248E-03 0,04148723 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 7,248E-03 0,04135879 ! peptidyl-histidine modification GO:0018202 5 5 0,000 7,248E-03 0,04123114 ! nucleosome positioning GO:0016584 5 5 0,000 7,248E-03 0,04110427 ! regulation of isotype switching GO:0045191 5 5 0,000 7,248E-03 0,04097819 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 7,248E-03 0,04085287 ! negative regulation of neurological system process GO:0031645 5 5 0,000 7,248E-03 0,04072832 ! glutathione biosynthetic process GO:0006750 5 5 0,000 7,248E-03 0,04060453 ! NADPH regeneration GO:0006740 5 5 0,000 7,248E-03 0,04048148 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 7,248E-03 0,04035918 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 7,248E-03 0,04023762 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 7,248E-03 0,04011678 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 7,248E-03 0,03999667 ! sarcomere organization GO:0045214 5 5 0,000 7,248E-03 0,03987728 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 7,248E-03 0,0397586 ! negative regulation of glucose transport GO:0010829 5 5 0,000 7,248E-03 0,03964062 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 7,248E-03 0,03952334 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 7,248E-03 0,03940675 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 7,248E-03 0,03929085 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 7,248E-03 0,03917563 ! spleen development GO:0048536 5 5 0,000 7,248E-03 0,03906108 ! male genitalia development GO:0030539 5 5 0,000 7,248E-03 0,0389472 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 7,248E-03 0,03883398 ! quaternary ammonium group transport GO:0015697 5 5 0,000 7,248E-03 0,03872142 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 7,248E-03 0,03860951 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 7,248E-03 0,03849824 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 7,248E-03 0,03838761 ! removal of superoxide radicals GO:0019430 6 5 0,000 7,248E-03 0,03827762 ! myeloid cell homeostasis GO:0002262 5 5 0,000 7,248E-03 0,03816825 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 7,248E-03 0,03805951 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 7,248E-03 0,03795139 ! ATP catabolic process GO:0006200 5 5 0,000 7,248E-03 0,03784388 ! lymphocyte activation during immune response GO:0002285 5 5 0,000 7,248E-03 0,03773697 ! blastocyst formation GO:0001825 5 5 0,000 7,248E-03 0,03763067 ! regulation of fibrinolysis GO:0051917 5 5 0,000 7,248E-03 0,03752497 ! embryonic gut development GO:0048566 5 5 0,000 7,248E-03 0,03741986 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 7,248E-03 0,03731533 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 7,248E-03 0,03721139 ! activation of innate immune response GO:0002218 5 5 0,000 7,248E-03 0,03710802 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 7,248E-03 0,03700523 ! catecholamine transport GO:0051937 5 5 0,000 7,248E-03 0,03690301 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 7,248E-03 0,03680135 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 7,248E-03 0,03670024 ! muscle adaptation GO:0043500 5 5 0,000 7,248E-03 0,0365997 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 7,248E-03 0,0364997 ! embryonic heart tube development GO:0035050 5 5 0,000 7,248E-03 0,03640024 ! cardiac cell differentiation GO:0035051 6 5 0,000 7,248E-03 0,03630133 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 7,248E-03 0,03620295 ! defense response to fungus GO:0050832 5 5 0,000 7,248E-03 0,0361051 ! lysogeny GO:0030069 5 5 0,000 7,248E-03 0,03600779 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 7,248E-03 0,03591099 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 7,248E-03 0,03581472 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 7,248E-03 0,03571895 ! response to nicotine GO:0035094 5 5 0,000 7,248E-03 0,0356237 ! establishment of cell polarity GO:0030010 5 5 0,000 7,248E-03 0,03552896 ! mitochondrion localization GO:0051646 5 5 0,000 7,248E-03 0,03543472 ! nucleus localization GO:0051647 5 5 0,000 7,248E-03 0,03534098 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 7,248E-03 0,03524773 ! negative regulation of cell cycle GO:0045786 92 91 1,000 7,268E-03 0,03524738 ! tissue morphogenesis GO:0048729 94 93 1,000 7,58E-03 0,0366689 ! blood vessel development GO:0001568 95 94 1,000 7,739E-03 0,03733897 ! pattern specification process GO:0007389 96 94 1,000 7,739E-03 0,03724148 ! regulation of cell growth GO:0001558 97 96 1,000 8,061E-03 0,03869048 ! vasculature development GO:0001944 97 96 1,000 8,061E-03 0,03858999 ! endocytosis GO:0006897 99 98 1,000 8,39E-03 0,04005683 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 8,39E-03 0,03995333 ! anti-apoptosis GO:0006916 100 99 1,000 8,556E-03 0,04064044 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 8,692E-03 0,04118299 ! axon extension GO:0048675 7 6 0,000 8,692E-03 0,0410774 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 8,692E-03 0,04097234 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 8,692E-03 0,04086782 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 8,692E-03 0,04076383 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 8,692E-03 0,04066037 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 8,692E-03 0,04055743 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 8,692E-03 0,04045501 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 8,692E-03 0,04035311 ! virus-host interaction GO:0019048 6 6 0,000 8,692E-03 0,04025172 ! regulation of S phase GO:0033261 6 6 0,000 8,692E-03 0,04015084 ! myotube differentiation GO:0014902 6 6 0,000 8,692E-03 0,04005046 ! regulation of B cell proliferation GO:0030888 6 6 0,000 8,692E-03 0,03995059 ! bone remodeling GO:0046849 6 6 0,000 8,692E-03 0,03985121 ! N-glycan processing GO:0006491 6 6 0,000 8,692E-03 0,03975232 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 8,692E-03 0,03965392 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 8,692E-03 0,03955601 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 8,692E-03 0,03945858 ! retina development in camera-type eye GO:0060041 6 6 0,000 8,692E-03 0,03936163 ! RNA methylation GO:0001510 6 6 0,000 8,692E-03 0,03926516 ! cartilage condensation GO:0001502 7 6 0,000 8,692E-03 0,03916916 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 8,692E-03 0,03907362 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 8,692E-03 0,03897855 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 8,692E-03 0,03888394 ! artery development GO:0060840 6 6 0,000 8,692E-03 0,03878979 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 8,692E-03 0,0386961 ! bile acid metabolic process GO:0008206 6 6 0,000 8,692E-03 0,03860286 ! androgen metabolic process GO:0008209 6 6 0,000 8,692E-03 0,03851006 ! estrogen metabolic process GO:0008210 6 6 0,000 8,692E-03 0,03841771 ! limbic system development GO:0021761 7 6 0,000 8,692E-03 0,0383258 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 8,692E-03 0,03823433 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 8,692E-03 0,0381433 ! positive regulation of heart contraction GO:0045823 6 6 0,000 8,692E-03 0,0380527 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 8,692E-03 0,03796252 ! pathogenesis GO:0009405 6 6 0,000 8,692E-03 0,03787278 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 8,692E-03 0,03778346 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 8,692E-03 0,03769455 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 8,692E-03 0,03760607 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 8,692E-03 0,037518 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 8,692E-03 0,03743034 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 8,692E-03 0,03734309 ! arginine metabolic process GO:0006525 6 6 0,000 8,692E-03 0,03725624 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 8,692E-03 0,0371698 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 8,692E-03 0,03708376 ! glutamate catabolic process GO:0006538 7 6 0,000 8,692E-03 0,03699812 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 8,692E-03 0,03691287 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 8,692E-03 0,03682801 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 8,692E-03 0,03674354 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 8,692E-03 0,03665946 ! ER overload response GO:0006983 6 6 0,000 8,692E-03 0,03657576 ! V(D)J recombination GO:0033151 6 6 0,000 8,692E-03 0,03649245 ! focal adhesion formation GO:0048041 7 6 0,000 8,692E-03 0,03640951 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 8,692E-03 0,03632695 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 8,692E-03 0,03624476 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 8,692E-03 0,03616295 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 8,692E-03 0,0360815 ! regulation of heart rate GO:0002027 6 6 0,000 8,692E-03 0,03600042 ! lipid digestion GO:0044241 6 6 0,000 8,692E-03 0,0359197 ! asymmetric protein localization GO:0008105 6 6 0,000 8,692E-03 0,03583934 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 8,692E-03 0,03575934 ! phagocytosis, engulfment GO:0006911 6 6 0,000 8,692E-03 0,0356797 ! Rac protein signal transduction GO:0016601 6 6 0,000 8,692E-03 0,03560041 ! regulation of vascular permeability GO:0043114 6 6 0,000 8,692E-03 0,03552147 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 8,692E-03 0,03544289 ! ruffle organization GO:0031529 6 6 0,000 8,692E-03 0,03536465 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 8,692E-03 0,03528675 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 8,692E-03 0,0352092 ! retinoic acid metabolic process GO:0042573 6 6 0,000 8,692E-03 0,03513198 ! neutral amino acid transport GO:0015804 6 6 0,000 8,692E-03 0,03505511 ! L-amino acid transport GO:0015807 6 6 0,000 8,692E-03 0,03497857 ! bone mineralization GO:0030282 6 6 0,000 8,692E-03 0,03490236 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 8,692E-03 0,03482649 ! negative regulation of ossification GO:0030279 6 6 0,000 8,692E-03 0,03475094 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 8,692E-03 0,03467573 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 8,692E-03 0,03460083 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 8,692E-03 0,03452626 ! purine base biosynthetic process GO:0009113 6 6 0,000 8,692E-03 0,03445201 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 8,692E-03 0,03437808 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 8,692E-03 0,03430446 ! regulation of phagocytosis GO:0050764 6 6 0,000 8,692E-03 0,03423116 ! regulation of organ growth GO:0046620 6 6 0,000 8,692E-03 0,03415818 ! regulation of circadian rhythm GO:0042752 6 6 0,000 8,692E-03 0,0340855 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 8,692E-03 0,03401313 ! response to dsRNA GO:0043331 6 6 0,000 8,692E-03 0,03394107 ! DNA unwinding during replication GO:0006268 6 6 0,000 8,692E-03 0,03386931 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 8,692E-03 0,03379786 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 8,692E-03 0,03372671 ! genitalia development GO:0048806 6 6 0,000 8,692E-03 0,03365585 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 8,692E-03 0,03358529 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 8,692E-03 0,03351503 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 8,692E-03 0,03344506 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 8,692E-03 0,03337539 ! multicellular organismal aging GO:0010259 6 6 0,000 8,692E-03 0,033306 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 8,692E-03 0,0332369 ! erythrocyte development GO:0048821 6 6 0,000 8,692E-03 0,03316808 ! renal water homeostasis GO:0003091 6 6 0,000 8,692E-03 0,03309956 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 8,692E-03 0,03303131 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 8,692E-03 0,03296334 ! ribosome assembly GO:0042255 6 6 0,000 8,692E-03 0,03289566 ! diencephalon development GO:0021536 6 6 0,000 8,692E-03 0,03282825 ! fucose catabolic process GO:0019317 6 6 0,000 8,692E-03 0,03276111 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 8,692E-03 0,03269426 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 8,692E-03 0,03262767 ! regulation of lipid transport GO:0032368 6 6 0,000 8,692E-03 0,03256135 ! regulation of cell division GO:0051302 6 6 0,000 8,692E-03 0,0324953 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 8,692E-03 0,03242952 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 8,692E-03 0,03236401 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 8,692E-03 0,03229876 ! salivary gland morphogenesis GO:0007435 6 6 0,000 8,692E-03 0,03223377 ! neuroblast proliferation GO:0007405 6 6 0,000 8,692E-03 0,03216905 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 8,692E-03 0,03210458 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 8,692E-03 0,03204037 ! regulation of glucose transport GO:0010827 6 6 0,000 8,692E-03 0,03197642 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 8,692E-03 0,03191272 ! methionine biosynthetic process GO:0009086 6 6 0,000 8,692E-03 0,03184927 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 8,692E-03 0,03178608 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 8,692E-03 0,03172314 ! thymus development GO:0048538 6 6 0,000 8,692E-03 0,03166044 ! lymph node development GO:0048535 6 6 0,000 8,692E-03 0,031598 ! organic cation transport GO:0015695 6 6 0,000 8,692E-03 0,0315358 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 8,692E-03 0,03147384 ! regulation of RNA splicing GO:0043484 6 6 0,000 8,692E-03 0,03141213 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 8,692E-03 0,03135066 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 8,692E-03 0,03128942 ! sperm-egg recognition GO:0035036 7 6 0,000 8,692E-03 0,03122843 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 8,692E-03 0,03116768 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 8,692E-03 0,03110716 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 8,692E-03 0,03104687 ! alditol metabolic process GO:0019400 6 6 0,000 8,692E-03 0,03098682 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 8,692E-03 0,030927 ! regulation of amino acid transport GO:0051955 6 6 0,000 8,692E-03 0,03086741 ! maternal placenta development GO:0001893 6 6 0,000 8,692E-03 0,03080805 ! regulation of embryonic development GO:0045995 6 6 0,000 8,692E-03 0,03074892 ! negative regulation of immune effector process GO:0002698 6 6 0,000 8,692E-03 0,03069001 ! localization within membrane GO:0051668 6 6 0,000 8,692E-03 0,03063133 ! response to hormone stimulus GO:0009725 102 100 1,000 8,724E-03 0,03068284 ! response to other organism GO:0051707 101 100 1,000 8,724E-03 0,0306244 ! respiratory burst GO:0045730 7 7 0,000 0,01013456 0,0355095 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,01013456 0,03544212 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,01013456 0,03537499 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,01013456 0,03530812 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,01013456 0,0352415 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,01013456 0,03517514 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,01013456 0,03510902 ! regulation of chemokine production GO:0032642 7 7 0,000 0,01013456 0,03504315 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,01013456 0,03497752 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,01013456 0,03491214 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,01013456 0,03484701 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,01013456 0,03478212 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,01013456 0,03471747 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,01013456 0,03465306 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,01013456 0,03458888 ! axis specification GO:0009798 7 7 0,000 0,01013456 0,03452495 ! visual behavior GO:0007632 7 7 0,000 0,01013456 0,03446125 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,01013456 0,03439778 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,01013456 0,03433455 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,01013456 0,03427155 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,01013456 0,03420879 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,01013456 0,03414625 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,01013456 0,03408394 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,01013456 0,03402185 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,01013456 0,03395999 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,01013456 0,03389836 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,01013456 0,03383695 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,01013456 0,03377576 ! protein targeting to ER GO:0045047 8 7 0,000 0,01013456 0,0337148 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,01013456 0,03365405 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,01013456 0,03359352 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,01013456 0,03353321 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,01013456 0,03347311 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,01013456 0,03341323 ! response to hexose stimulus GO:0009746 7 7 0,000 0,01013456 0,03335357 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,01013456 0,03329411 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,01013456 0,03323487 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,01013456 0,03317584 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,01013456 0,03311702 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,01013456 0,0330584 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,01013456 0,03299999 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,01013456 0,03294179 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,01013456 0,0328838 ! response to X-ray GO:0010165 7 7 0,000 0,01013456 0,032826 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,01013456 0,03276842 ! UV protection GO:0009650 7 7 0,000 0,01013456 0,03271103 ! DNA integration GO:0015074 7 7 0,000 0,01013456 0,03265384 ! myofibril assembly GO:0030239 7 7 0,000 0,01013456 0,03259685 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,01013456 0,03254006 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,01013456 0,03248347 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,01013456 0,03242708 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,01013456 0,03237088 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,01013456 0,03231487 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,01013456 0,03225906 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,01013456 0,03220344 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,01013456 0,03214802 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,01013456 0,03209278 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,01013456 0,03203773 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,01013456 0,03198287 ! axon cargo transport GO:0008088 7 7 0,000 0,01013456 0,0319282 ! eating behavior GO:0042755 7 7 0,000 0,01013456 0,03187371 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,01013456 0,03181942 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,01013456 0,0317653 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,01013456 0,03171137 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,01013456 0,03165762 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,01013456 0,03160406 ! cranial nerve development GO:0021545 7 7 0,000 0,01013456 0,03155067 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,01013456 0,03149747 ! induction of an organ GO:0001759 7 7 0,000 0,01013456 0,03144444 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,01013456 0,03139159 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,01013456 0,03133892 ! autonomic nervous system development GO:0048483 7 7 0,000 0,01013456 0,03128643 ! intracellular lipid transport GO:0032365 7 7 0,000 0,01013456 0,03123411 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,01013456 0,03118196 ! platelet activation GO:0030168 8 7 0,000 0,01013456 0,03112999 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,01013456 0,0310782 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,01013456 0,03102657 ! natural killer cell activation GO:0030101 7 7 0,000 0,01013456 0,03097512 ! response to gamma radiation GO:0010332 8 7 0,000 0,01013456 0,03092384 ! NADP metabolic process GO:0006739 7 7 0,000 0,01013456 0,03087272 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,01013456 0,03082178 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,01013456 0,030771 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,01013456 0,03072039 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,01013456 0,03066995 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,01013456 0,03061967 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,01013456 0,03056955 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,01013456 0,0305196 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,01013456 0,03046982 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,01013456 0,03042019 ! cell-cell recognition GO:0009988 8 7 0,000 0,01013456 0,03037073 ! hormone catabolic process GO:0042447 7 7 0,000 0,01013456 0,03032142 ! dopamine metabolic process GO:0042417 7 7 0,000 0,01013456 0,03027228 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,01013456 0,0302233 ! oxygen transport GO:0015671 7 7 0,000 0,01013456 0,03017447 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,01013456 0,0301258 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,01013456 0,03007729 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,01013456 0,03002893 ! regulation of axon extension GO:0030516 7 7 0,000 0,01013456 0,02998073 ! cell killing GO:0001906 7 7 0,000 0,01013456 0,02993269 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,01013456 0,02988479 ! adult feeding behavior GO:0008343 7 7 0,000 0,01013456 0,02983706 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,01013456 0,02978947 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,01013456 0,02974203 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,01013456 0,02969475 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,01013456 0,02964761 ! response to cold GO:0009409 7 7 0,000 0,01013456 0,02960063 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,01157478 0,03375368 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,01157478 0,03370036 ! positive regulation of translation GO:0045727 8 8 0,000 0,01157478 0,03364721 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,01157478 0,03359422 ! superoxide anion generation GO:0042554 8 8 0,000 0,01157478 0,0335414 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,01157478 0,03348874 ! cGMP metabolic process GO:0046068 8 8 0,000 0,01157478 0,03343625 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,01157478 0,03338393 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,01157478 0,03333176 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,01157478 0,03327976 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,01157478 0,03322793 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,01157478 0,03317625 ! zinc ion transport GO:0006829 8 8 0,000 0,01157478 0,03312473 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,01157478 0,03307338 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,01157478 0,03302218 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,01157478 0,03297114 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,01157478 0,03292026 ! lipid localization GO:0010876 8 8 0,000 0,01157478 0,03286953 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,01157478 0,03281897 ! response to cAMP GO:0051591 8 8 0,000 0,01157478 0,03276855 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,01157478 0,03271829 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,01157478 0,03266819 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,01157478 0,03261824 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,01157478 0,03256844 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,01157478 0,03251879 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,01157478 0,0324693 ! sensory perception of taste GO:0050909 8 8 0,000 0,01157478 0,03241995 ! organelle fusion GO:0048284 8 8 0,000 0,01157478 0,03237076 ! pancreas development GO:0031016 8 8 0,000 0,01157478 0,03232171 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,01157478 0,03227281 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,01157478 0,03222406 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,01157478 0,03217546 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,01157478 0,032127 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,01157478 0,03207869 ! sperm motility GO:0030317 8 8 0,000 0,01157478 0,03203052 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,01157478 0,0319825 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,01157478 0,03193462 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,01157478 0,03188689 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,01157478 0,0318393 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,01157478 0,03179185 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01157478 0,03174454 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,01157478 0,03169737 ! Golgi organization GO:0007030 8 8 0,000 0,01157478 0,03165034 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,01157478 0,03160345 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,01157478 0,0315567 ! fructose metabolic process GO:0006000 8 8 0,000 0,01157478 0,03151009 ! mannose metabolic process GO:0006013 9 8 0,000 0,01157478 0,03146361 ! NAD metabolic process GO:0019674 8 8 0,000 0,01157478 0,03141727 ! sex determination GO:0007530 8 8 0,000 0,01157478 0,03137107 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,01157478 0,031325 ! plasma membrane fusion GO:0045026 8 8 0,000 0,01157478 0,03127907 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,01157478 0,03123328 ! response to fungus GO:0009620 8 8 0,000 0,01157478 0,03118761 ! stem cell differentiation GO:0048863 8 8 0,000 0,01157478 0,03114208 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,01157478 0,03109669 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,01157478 0,03105142 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,01157478 0,03100629 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,01157478 0,03096129 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01157478 0,03091642 ! regulation of vasodilation GO:0042312 8 8 0,000 0,01157478 0,03087168 ! vasoconstriction GO:0042310 8 8 0,000 0,01157478 0,03082706 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,01157478 0,03078258 ! muscle cell development GO:0055001 8 8 0,000 0,01157478 0,03073823 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,01157478 0,030694 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,01157478 0,0306499 ! sensory perception of pain GO:0019233 8 8 0,000 0,01157478 0,03060592 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,01157478 0,03056207 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,01157478 0,03051835 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,01157478 0,03047475 ! chromatin silencing GO:0006342 8 8 0,000 0,01157478 0,03043128 ! tissue regeneration GO:0042246 8 8 0,000 0,01157478 0,03038793 ! salivary gland development GO:0007431 8 8 0,000 0,01157478 0,03034471 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,01157478 0,0303016 ! T cell homeostasis GO:0043029 8 8 0,000 0,01157478 0,03025862 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,01157478 0,03021576 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,01157478 0,03017302 ! water homeostasis GO:0030104 8 8 0,000 0,01157478 0,03013041 ! cofactor transport GO:0051181 8 8 0,000 0,01157478 0,03008791 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,01157478 0,03004553 ! acid secretion GO:0046717 8 8 0,000 0,01157478 0,03000327 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,01157478 0,02996114 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,01157478 0,02991911 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,01157478 0,02987721 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,01157478 0,02983542 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,01157478 0,02979375 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,01157478 0,0297522 ! regulation of RNA stability GO:0043487 8 8 0,000 0,01157478 0,02971076 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,01157478 0,02966944 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,01157478 0,02962823 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,01157478 0,02958714 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,01157478 0,02954616 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,01157478 0,02950529 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,01157478 0,02946454 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,01157478 0,0294239 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,01157478 0,02938337 ! developmental induction GO:0031128 8 8 0,000 0,01157478 0,02934295 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,01157478 0,02930265 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,01157478 0,02926245 ! actin filament polymerization GO:0030041 9 8 0,000 0,01157478 0,02922237 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,01157478 0,02918239 ! peptide hormone processing GO:0016486 8 8 0,000 0,01157478 0,02914252 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,01157478 0,02910277 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,01157478 0,02906312 ! lactation GO:0007595 10 9 0,000 0,01301312 0,03263018 ! embryonic pattern specification GO:0009880 10 9 0,000 0,01301312 0,03258585 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,01301312 0,03254163 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,01301312 0,03249754 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,01301312 0,03245356 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,01301312 0,03240971 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,01301312 0,03236597 ! viral genome replication GO:0019079 9 9 0,000 0,01301312 0,03232235 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,01301312 0,03227885 ! copper ion transport GO:0006825 9 9 0,000 0,01301312 0,03223546 ! lipid phosphorylation GO:0046834 9 9 0,000 0,01301312 0,03219219 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,01301312 0,03214904 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,01301312 0,032106 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,01301312 0,03206308 ! RNA polyadenylation GO:0043631 9 9 0,000 0,01301312 0,03202027 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,01301312 0,03197758 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,01301312 0,031935 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,01301312 0,03189253 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,01301312 0,03185018 ! phospholipid efflux GO:0033700 9 9 0,000 0,01301312 0,03180794 ! response to alkaloid GO:0043279 10 9 0,000 0,01301312 0,03176581 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,01301312 0,03172379 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,01301312 0,03168188 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,01301312 0,03164008 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,01301312 0,0315984 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,01301312 0,03155682 ! response to ethanol GO:0045471 9 9 0,000 0,01301312 0,03151535 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,01301312 0,03147399 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,01301312 0,03143274 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,01301312 0,0313916 ! methionine metabolic process GO:0006555 9 9 0,000 0,01301312 0,03135057 ! glutamine metabolic process GO:0006541 9 9 0,000 0,01301312 0,03130964 ! cerebral cortex development GO:0021987 9 9 0,000 0,01301312 0,03126882 ! response to osmotic stress GO:0006970 9 9 0,000 0,01301312 0,0312281 ! pigmentation during development GO:0048066 9 9 0,000 0,01301312 0,03118749 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,01301312 0,03114699 ! central nervous system neuron development GO:0021954 10 9 0,000 0,01301312 0,03110659 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,01301312 0,0310663 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,01301312 0,03102611 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,01301312 0,03098603 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,01301312 0,03094604 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,01301312 0,03090616 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,01301312 0,03086639 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,01301312 0,03082671 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,01301312 0,03078714 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,01301312 0,03074767 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,01301312 0,0307083 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,01301312 0,03066903 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,01301312 0,03062986 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,01301312 0,0305908 ! DNA replication initiation GO:0006270 9 9 0,000 0,01301312 0,03055183 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,01301312 0,03051296 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,01301312 0,03047418 ! regulation of cellular pH GO:0030641 9 9 0,000 0,01301312 0,03043551 ! histone acetylation GO:0016573 9 9 0,000 0,01301312 0,03039694 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,01301312 0,03035846 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,01301312 0,03032008 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,01301312 0,0302818 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,01301312 0,03024361 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,01301312 0,03020552 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,01301312 0,03016753 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,01301312 0,03012963 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,01301312 0,03009182 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,01301312 0,03005411 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,01301312 0,0300165 ! collagen catabolic process GO:0030574 9 9 0,000 0,01301312 0,02997898 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,01301312 0,02994155 ! purine base metabolic process GO:0006144 9 9 0,000 0,01301312 0,02990422 ! gas transport GO:0015669 9 9 0,000 0,01301312 0,02986698 ! cholesterol efflux GO:0033344 9 9 0,000 0,01301312 0,02982983 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,01301312 0,02979277 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,01301312 0,02975581 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,01301312 0,02971894 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,01301312 0,02968216 ! defense response to virus GO:0051607 9 9 0,000 0,01301312 0,02964547 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,01301312 0,02960887 ! actin filament-based movement GO:0030048 9 9 0,000 0,01301312 0,02957236 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,01301312 0,02953594 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01444957 0,03275592 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01444957 0,03271568 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01444957 0,03267554 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,01444957 0,0326355 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01444957 0,03259555 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01444957 0,0325557 ! neuron maturation GO:0042551 10 10 0,000 0,01444957 0,03251595 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01444957 0,0324763 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01444957 0,03243674 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01444957 0,03239728 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01444957 0,03235792 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01444957 0,03231865 ! hormone secretion GO:0046879 10 10 0,000 0,01444957 0,03227947 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01444957 0,0322404 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01444957 0,03220141 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,01444957 0,03216252 ! inositol metabolic process GO:0006020 10 10 0,000 0,01444957 0,03212372 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01444957 0,03208502 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01444957 0,03204641 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01444957 0,03200789 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01444957 0,03196947 ! glial cell development GO:0021782 10 10 0,000 0,01444957 0,03193113 ! phototransduction GO:0007602 11 10 0,000 0,01444957 0,03189289 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01444957 0,03185474 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01444957 0,03181669 ! fat cell differentiation GO:0045444 10 10 0,000 0,01444957 0,03177872 ! myoblast differentiation GO:0045445 10 10 0,000 0,01444957 0,03174084 ! centrosome cycle GO:0007098 10 10 0,000 0,01444957 0,03170306 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01444957 0,03166536 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01444957 0,03162775 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01444957 0,03159023 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01444957 0,0315528 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01444957 0,03151546 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01444957 0,03147821 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01444957 0,03144105 ! plasma membrane organization GO:0007009 10 10 0,000 0,01444957 0,03140397 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01444957 0,03136698 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01444957 0,03133008 ! lysosomal transport GO:0007041 10 10 0,000 0,01444957 0,03129326 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01444957 0,03125653 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01444957 0,03121989 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,01444957 0,03118333 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,01444957 0,03114686 ! exocrine system development GO:0035272 10 10 0,000 0,01444957 0,03111047 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01444957 0,03107417 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01444957 0,03103796 ! embryo implantation GO:0007566 11 10 0,000 0,01444957 0,03100182 ! regulation of protein binding GO:0043393 11 10 0,000 0,01444957 0,03096577 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01444957 0,03092981 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01444957 0,03089393 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,01444957 0,03085813 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01444957 0,03082241 ! protein export from nucleus GO:0006611 10 10 0,000 0,01444957 0,03078678 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01444957 0,03075123 ! cytolysis GO:0019835 10 10 0,000 0,01444957 0,03071576 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01444957 0,03068038 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01444957 0,03064507 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01444957 0,03060985 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01444957 0,0305747 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01444957 0,03053964 ! gland morphogenesis GO:0022612 10 10 0,000 0,01444957 0,03050466 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01444957 0,03046976 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01444957 0,03043493 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01444957 0,03040019 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01444957 0,03036553 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,01444957 0,03033094 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01444957 0,03029643 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01444957 0,03026201 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01444957 0,03022766 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01444957 0,03019339 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01444957 0,03015919 ! nerve development GO:0021675 10 10 0,000 0,01444957 0,03012508 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01444957 0,03009104 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,01444957 0,03005707 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01444957 0,03002319 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01444957 0,02998938 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01444957 0,02995564 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01444957 0,02992198 ! protein stabilization GO:0050821 10 10 0,000 0,01444957 0,0298884 ! protein secretion GO:0009306 11 11 0,000 0,01588415 0,03281892 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01588415 0,03278217 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01588415 0,0327455 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01588415 0,03270892 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01588415 0,03267241 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01588415 0,03263599 ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01588415 0,03259964 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01588415 0,03256338 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,01588415 0,0325272 ! signal complex assembly GO:0007172 11 11 0,000 0,01588415 0,0324911 ! microtubule-based transport GO:0010970 11 11 0,000 0,01588415 0,03245508 ! endothelial cell migration GO:0043542 11 11 0,000 0,01588415 0,03241914 ! peroxisomal transport GO:0043574 11 11 0,000 0,01588415 0,03238328 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01588415 0,03234749 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,01588415 0,03231179 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01588415 0,03227616 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01588415 0,03224062 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01588415 0,03220515 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01588415 0,03216976 ! T cell proliferation GO:0042098 11 11 0,000 0,01588415 0,03213445 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01588415 0,03209921 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01588415 0,03206405 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,01588415 0,03202897 ! spinal cord development GO:0021510 11 11 0,000 0,01588415 0,03199397 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01588415 0,03195904 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01588415 0,03192419 ! cellular response to starvation GO:0009267 11 11 0,000 0,01588415 0,03188941 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01588415 0,03185471 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,01588415 0,03182009 ! digestive system process GO:0022600 11 11 0,000 0,01588415 0,03178554 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01588415 0,03175106 ! fucose metabolic process GO:0006004 11 11 0,000 0,01588415 0,03171666 ! membrane budding GO:0006900 11 11 0,000 0,01588415 0,03168234 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,01588415 0,03164809 ! monoamine transport GO:0015844 11 11 0,000 0,01588415 0,03161391 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01588415 0,03157981 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01588415 0,03154578 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01588415 0,03151182 ! body fluid secretion GO:0007589 11 11 0,000 0,01588415 0,03147794 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01588415 0,03144413 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,01588415 0,03141039 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01588415 0,03137672 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01588415 0,03134313 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01588415 0,03130961 ! membrane depolarization GO:0051899 11 11 0,000 0,01588415 0,03127615 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01588415 0,03124278 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01588415 0,03120947 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,01588415 0,03117623 ! oogenesis GO:0048477 11 11 0,000 0,01588415 0,03114306 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01588415 0,03110997 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01588415 0,03107694 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,01588415 0,03104399 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,01588415 0,0310111 ! muscle maintenance GO:0046716 12 11 0,000 0,01588415 0,03097829 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01588415 0,03094554 ! hindbrain development GO:0030902 11 11 0,000 0,01588415 0,03091286 ! steroid catabolic process GO:0006706 11 11 0,000 0,01588415 0,03088025 ! endocrine process GO:0050886 11 11 0,000 0,01588415 0,03084771 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01588415 0,03081524 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01588415 0,03078284 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01588415 0,03075051 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,01588415 0,03071824 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01588415 0,03068604 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,01731684 0,03341878 ! translational initiation GO:0006413 12 12 0,000 0,01731684 0,03338382 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,01731684 0,03334894 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,01731684 0,03331412 ! initiation of viral infection GO:0019059 12 12 0,000 0,01731684 0,03327939 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,01731684 0,03324472 ! iron ion transport GO:0006826 13 12 0,000 0,01731684 0,03321013 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,01731684 0,0331756 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,01731684 0,03314115 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,01731684 0,03310678 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,01731684 0,03307247 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,01731684 0,03303823 ! collagen metabolic process GO:0032963 12 12 0,000 0,01731684 0,03300407 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,01731684 0,03296997 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,01731684 0,03293595 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,01731684 0,03290199 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,01731684 0,03286811 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,01731684 0,03283429 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,01731684 0,03280055 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,01731684 0,03276687 ! retinoid metabolic process GO:0001523 12 12 0,000 0,01731684 0,03273326 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,01731684 0,03269973 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,01731684 0,03266626 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,01731684 0,03263285 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,01731684 0,03259952 ! acute-phase response GO:0006953 12 12 0,000 0,01731684 0,03256626 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01731684 0,03253306 ! vacuolar transport GO:0007034 12 12 0,000 0,01731684 0,03249993 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,01731684 0,03246687 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,01731684 0,03243387 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,01731684 0,03240095 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,01731684 0,03236808 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,01731684 0,03233529 ! male gonad development GO:0008584 12 12 0,000 0,01731684 0,03230256 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,01731684 0,0322699 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,01731684 0,0322373 ! renal system process GO:0003014 12 12 0,000 0,01731684 0,03220477 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,01731684 0,03217231 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,01731684 0,03213991 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,01731684 0,03210758 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,01731684 0,03207531 ! pallium development GO:0021543 13 12 0,000 0,01731684 0,0320431 ! cell fate determination GO:0001709 12 12 0,000 0,01731684 0,03201096 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,01731684 0,03197889 ! somitogenesis GO:0001756 13 12 0,000 0,01731684 0,03194688 ! G1 phase GO:0051318 13 12 0,000 0,01731684 0,03191493 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,01731684 0,03188305 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,01731684 0,03185123 ! detection of light stimulus GO:0009583 13 12 0,000 0,01731684 0,03181947 ! synaptogenesis GO:0007416 12 12 0,000 0,01731684 0,03178778 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,01731684 0,03175615 ! hormone transport GO:0009914 12 12 0,000 0,01731684 0,03172458 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,01731684 0,03169308 ! heme biosynthetic process GO:0006783 12 12 0,000 0,01731684 0,03166164 ! spermatid differentiation GO:0048515 13 12 0,000 0,01731684 0,03163026 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,01731684 0,03159894 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,01731684 0,03156769 ! neural tube closure GO:0001843 13 12 0,000 0,01731684 0,03153649 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,01731684 0,03150536 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,01731684 0,03147429 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,01874765 0,0340413 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,01874765 0,0340078 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,01874765 0,03397436 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,01874765 0,03394098 ! phenol metabolic process GO:0018958 13 13 0,000 0,01874765 0,03390768 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,01874765 0,03387443 ! gluconeogenesis GO:0006094 13 13 0,000 0,01874765 0,03384126 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,01874765 0,03380814 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,01874765 0,03377509 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,01874765 0,03374211 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,01874765 0,03370919 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,01874765 0,03367634 ! regeneration GO:0031099 13 13 0,000 0,01874765 0,03364355 ! keratinization GO:0031424 13 13 0,000 0,01874765 0,03361082 ! post-embryonic development GO:0009791 14 13 0,000 0,01874765 0,03357816 ! patterning of blood vessels GO:0001569 13 13 0,000 0,01874765 0,03354556 ! vasculogenesis GO:0001570 13 13 0,000 0,01874765 0,03351302 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,01874765 0,03348054 ! regulation of innate immune response GO:0045088 13 13 0,000 0,01874765 0,03344813 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,01874765 0,03341579 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,01874765 0,0333835 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,01874765 0,03335128 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,01874765 0,03331911 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,01874765 0,03328702 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,01874765 0,03325498 ! autophagy GO:0006914 13 13 0,000 0,01874765 0,033223 ! receptor metabolic process GO:0043112 14 13 0,000 0,01874765 0,03319109 ! actin filament bundle formation GO:0051017 13 13 0,000 0,01874765 0,03315923 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,01874765 0,03312744 ! ureteric bud development GO:0001657 13 13 0,000 0,01874765 0,03309571 ! cell aging GO:0007569 13 13 0,000 0,01874765 0,03306404 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,01874765 0,03303243 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,01874765 0,03300088 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,01874765 0,03296939 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,01874765 0,03293796 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,01874765 0,03290659 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,01874765 0,03287528 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,01874765 0,03284403 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,01874765 0,03281284 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,01874765 0,03278171 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,01874765 0,03275064 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,01874765 0,03271962 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,01874765 0,03268867 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,01874765 0,03265777 ! vasodilation GO:0042311 14 13 0,000 0,01874765 0,03262693 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,01874765 0,03259615 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,01874765 0,03256543 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,01874765 0,03253477 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,01874765 0,03250416 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,01874765 0,03247361 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,01874765 0,03244312 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,01874765 0,03241268 ! immunoglobulin production GO:0002377 13 13 0,000 0,01874765 0,03238231 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,01874765 0,03235199 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,01874765 0,03232172 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,01874765 0,03229152 ! cell-cell junction organization GO:0045216 13 13 0,000 0,01874765 0,03226137 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,01874765 0,03223127 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,01874765 0,03220123 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,01874765 0,03217125 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,01874765 0,03214132 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,01874765 0,03211145 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,01874765 0,03208164 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,01874765 0,03205188 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,01874765 0,03202217 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,01874765 0,03199252 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,01874765 0,03196293 ! blastocyst development GO:0001824 13 13 0,000 0,01874765 0,03193338 ! telomere organization GO:0032200 13 13 0,000 0,01874765 0,0319039 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,01874765 0,03187447 ! regulation of amine transport GO:0051952 13 13 0,000 0,01874765 0,03184509 ! tissue homeostasis GO:0001894 13 13 0,000 0,01874765 0,03181577 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,01874765 0,0317865 ! protein tetramerization GO:0051262 13 13 0,000 0,01874765 0,03175728 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,02017659 0,03414642 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,02017659 0,0341151 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,02017659 0,03408383 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,02017659 0,03405262 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,02017659 0,03402146 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,02017659 0,03399036 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,02017659 0,03395932 ! protein amino acid acylation GO:0043543 14 14 0,000 0,02017659 0,03392834 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,02017659 0,03389741 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,02017659 0,03386654 ! vesicle docking GO:0048278 14 14 0,000 0,02017659 0,03383572 ! superoxide metabolic process GO:0006801 15 14 0,000 0,02017659 0,03380496 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,02017659 0,03377426 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,02017659 0,03374361 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,02017659 0,03371302 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,02017659 0,03368248 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,02017659 0,033652 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,02017659 0,03362157 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,02017659 0,0335912 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,02017659 0,03356088 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,02017659 0,03353062 ! lysosome organization GO:0007040 14 14 0,000 0,02017659 0,03350041 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,02017659 0,03347026 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,02017659 0,03344016 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,02017659 0,03341011 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,02017659 0,03338012 ! primary neural tube formation GO:0014020 15 14 0,000 0,02017659 0,03335019 ! peptide cross-linking GO:0018149 14 14 0,000 0,02017659 0,0333203 ! regulation of behavior GO:0050795 14 14 0,000 0,02017659 0,03329047 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,02017659 0,03326069 ! base-excision repair GO:0006284 14 14 0,000 0,02017659 0,03323097 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,02017659 0,0332013 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,02017659 0,03317168 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,02017659 0,03314212 ! formation of primary germ layer GO:0001704 14 14 0,000 0,02017659 0,03311261 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,02017659 0,03308315 ! collagen fibril organization GO:0030199 14 14 0,000 0,02017659 0,03305374 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,02017659 0,03302438 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,02017659 0,03299508 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,02017659 0,03296583 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,02017659 0,03293663 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,02017659 0,03290748 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,02017659 0,03287839 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,02017659 0,03284934 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,02017659 0,03282035 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,02017659 0,03279141 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,02160366 0,03507977 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,02160366 0,03504889 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,02160366 0,03501806 ! positive regulation of ossification GO:0045778 15 15 0,000 0,02160366 0,03498729 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,02160366 0,03495657 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,02160366 0,03492591 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,02160366 0,0348953 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,02160366 0,03486475 ! response to vitamin GO:0033273 15 15 0,000 0,02160366 0,03483424 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,02160366 0,03480379 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,02160366 0,0347734 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,02160366 0,03474305 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,02160366 0,03471276 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,02160366 0,03468253 ! ovarian follicle development GO:0001541 15 15 0,000 0,02160366 0,03465234 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,02160366 0,03462221 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,02160366 0,03459213 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,02160366 0,0345621 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,02160366 0,03453212 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,02160366 0,0345022 ! heme metabolic process GO:0042168 15 15 0,000 0,02160366 0,03447233 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,02160366 0,03444251 ! chromosome condensation GO:0030261 15 15 0,000 0,02160366 0,03441274 ! response to starvation GO:0042594 15 15 0,000 0,02160366 0,03438302 ! response to ionizing radiation GO:0010212 16 15 0,000 0,02160366 0,03435336 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,02160366 0,03432374 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,02160366 0,03429418 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,02160366 0,03426466 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,02160366 0,0342352 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,02160366 0,03420579 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,02160366 0,03417643 ! phospholipid transport GO:0015914 15 15 0,000 0,02160366 0,03414712 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,02160366 0,03411786 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,02160366 0,03408865 ! glutathione metabolic process GO:0006749 16 15 0,000 0,02160366 0,03405949 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,02160366 0,03403038 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,02160366 0,03400131 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,02160366 0,0339723 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,02160366 0,03394334 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,02160366 0,03391443 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,02160366 0,03388557 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,02160366 0,03385675 ! protein homooligomerization GO:0051260 15 15 0,000 0,02160366 0,03382799 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,02160366 0,03379927 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,02302885 0,03599845 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,02302885 0,03596794 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,02302885 0,03593749 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,02302885 0,03590708 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,02302885 0,03587673 ! learning GO:0007612 16 16 0,000 0,02302885 0,03584643 ! circadian rhythm GO:0007623 16 16 0,000 0,02302885 0,03581618 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,02302885 0,03578598 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,02302885 0,03575583 ! vacuole organization GO:0007033 16 16 0,000 0,02302885 0,03572574 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,02302885 0,03569569 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,02302885 0,03566569 ! vesicle targeting GO:0006903 17 16 0,000 0,02302885 0,03563575 ! segmentation GO:0035282 17 16 0,000 0,02302885 0,03560585 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,02302885 0,035576 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,02302885 0,03554621 ! iron ion homeostasis GO:0055072 16 16 0,000 0,02302885 0,03551646 ! positive regulation of cell development GO:0010720 16 16 0,000 0,02302885 0,03548677 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,02302885 0,03545712 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,02302885 0,03542752 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,02302885 0,03539798 ! pentose metabolic process GO:0019321 16 16 0,000 0,02302885 0,03536848 ! fatty acid transport GO:0015908 16 16 0,000 0,02302885 0,03533903 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,02302885 0,03530963 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,02302885 0,03528028 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,02302885 0,03525097 ! cofactor catabolic process GO:0051187 16 16 0,000 0,02302885 0,03522172 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,02302885 0,03519252 ! polyol metabolic process GO:0019751 16 16 0,000 0,02302885 0,03516336 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,02302885 0,03513425 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,02302885 0,03510519 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,02302885 0,03507618 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,02302885 0,03504721 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,02302885 0,03501829 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,02302885 0,03498943 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,02302885 0,0349606 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,02302885 0,03493183 ! regulation of coagulation GO:0050818 17 16 0,000 0,02302885 0,0349031 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,02445218 0,03702988 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,02445218 0,03699948 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,02445218 0,03696913 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,02445218 0,03693882 ! myelination GO:0042552 17 17 0,000 0,02445218 0,03690857 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,02445218 0,03687837 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,02445218 0,03684821 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,02445218 0,03681811 ! leukocyte adhesion GO:0007159 17 17 0,000 0,02445218 0,03678805 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,02445218 0,03675805 ! sensory perception of smell GO:0007608 17 17 0,000 0,02445218 0,03672809 ! glucose transport GO:0015758 17 17 0,000 0,02445218 0,03669818 ! cell junction assembly GO:0034329 18 17 0,000 0,02445218 0,03666832 ! tissue remodeling GO:0048771 17 17 0,000 0,02445218 0,03663851 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,02445218 0,03660874 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,02445218 0,03657903 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,02445218 0,03654936 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,02445218 0,03651974 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,02445218 0,03649017 ! neural crest cell development GO:0014032 19 17 0,000 0,02445218 0,03646065 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,02445218 0,03643118 ! negative regulation of cell development GO:0010721 18 17 0,000 0,02445218 0,03640175 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,02445218 0,03637237 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,02445218 0,03634304 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,02445218 0,03631375 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,02445218 0,03628451 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,02445218 0,03625532 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,02445218 0,03622618 ! pigmentation GO:0043473 17 17 0,000 0,02445218 0,03619708 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,02445218 0,03616803 ! adult locomotory behavior GO:0008344 17 17 0,000 0,02445218 0,03613902 ! embryonic organ development GO:0048568 17 17 0,000 0,02445218 0,03611007 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,02445218 0,03608116 ! liver development GO:0001889 17 17 0,000 0,02445218 0,03605229 ! gene silencing GO:0016458 17 17 0,000 0,02445218 0,03602347 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,02587364 0,03808715 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,02587364 0,03805675 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,02587364 0,03802641 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,02587364 0,03799611 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,02587364 0,03796585 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,02587364 0,03793565 ! membrane docking GO:0022406 18 18 0,000 0,02587364 0,0379055 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,02587364 0,03787539 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,02587364 0,03784533 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,02587364 0,03781532 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,02587364 0,03778535 ! hexose transport GO:0008645 18 18 0,000 0,02587364 0,03775543 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,02587364 0,03772556 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,02587364 0,03769574 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,02587364 0,03766597 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,02587364 0,03763624 ! ceramide metabolic process GO:0006672 18 18 0,000 0,02587364 0,03760656 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,02587364 0,03757692 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,02587364 0,03754733 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,02587364 0,03751779 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,02587364 0,0374883 ! B cell differentiation GO:0030183 18 18 0,000 0,02587364 0,03745885 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,02587364 0,03742945 ! ensheathment of neurons GO:0007272 18 18 0,000 0,02587364 0,03740009 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,02587364 0,03737078 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,02587364 0,03734151 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,02587364 0,0373123 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,02587364 0,03728312 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,02587364 0,037254 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,02729323 0,03926731 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,02729323 0,03923668 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,02729323 0,0392061 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,02729323 0,03917557 ! regulation of pH GO:0006885 19 19 0,000 0,02729323 0,03914508 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,02729323 0,03911464 ! feeding behavior GO:0007631 19 19 0,000 0,02729323 0,03908425 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,02729323 0,0390539 ! peroxisome organization GO:0007031 19 19 0,000 0,02729323 0,03902361 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,02729323 0,03899336 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,02729323 0,03896315 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,02729323 0,03893299 ! metanephros development GO:0001656 19 19 0,000 0,02729323 0,03890288 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,02729323 0,03887282 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,02729323 0,0388428 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,02729323 0,03881283 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,02729323 0,03878291 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,02729323 0,03875303 ! peripheral nervous system development GO:0007422 19 19 0,000 0,02729323 0,03872319 ! regulation of protein stability GO:0031647 19 19 0,000 0,02729323 0,03869341 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,02729323 0,03866367 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,02729323 0,03863397 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,02729323 0,03860432 ! eye morphogenesis GO:0048592 19 19 0,000 0,02729323 0,03857471 ! regulation of cell shape GO:0008360 21 19 0,000 0,02729323 0,03854516 ! placenta development GO:0001890 19 19 0,000 0,02729323 0,03851564 ! response to heat GO:0009408 19 19 0,000 0,02729323 0,03848617 ! vesicle localization GO:0051648 20 19 0,000 0,02729323 0,03845675 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,02871097 0,04042346 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,02871097 0,0403926 ! negative regulation of binding GO:0051100 21 20 0,000 0,02871097 0,04036179 ! organic ether metabolic process GO:0018904 20 20 0,000 0,02871097 0,04033103 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,02871097 0,04030031 ! neural tube development GO:0021915 21 20 0,000 0,02871097 0,04026964 ! nucleus organization GO:0006997 20 20 0,000 0,02871097 0,04023902 ! phagocytosis GO:0006909 21 20 0,000 0,02871097 0,04020844 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,02871097 0,04017791 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,02871097 0,04014743 ! protein targeting to membrane GO:0006612 22 20 0,000 0,02871097 0,04011699 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,02871097 0,0400866 ! chromatin remodeling GO:0006338 20 20 0,000 0,02871097 0,04005625 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,02871097 0,04002595 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,02871097 0,0399957 ! lipid oxidation GO:0034440 20 20 0,000 0,02871097 0,03996549 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,02871097 0,03993533 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,02871097 0,03990521 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,02871097 0,03987514 ! RNA modification GO:0009451 20 20 0,000 0,02871097 0,03984511 ! single fertilization GO:0007338 21 20 0,000 0,02871097 0,03981513 ! regulation of B cell activation GO:0050864 20 20 0,000 0,02871097 0,0397852 ! mRNA catabolic process GO:0006402 21 21 0,000 0,03012684 0,04171583 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,03012684 0,04168451 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,03012684 0,04165324 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,03012684 0,04162201 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,03012684 0,04159084 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,03012684 0,0415597 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,03012684 0,04152862 ! ear morphogenesis GO:0042471 21 21 0,000 0,03012684 0,04149758 ! organic anion transport GO:0015711 21 21 0,000 0,03012684 0,04146659 ! cholesterol transport GO:0030301 21 21 0,000 0,03012684 0,04143565 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,03012684 0,04140475 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,03012684 0,04137389 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,03012684 0,04134309 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,03012684 0,04131233 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,03012684 0,04128161 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,03012684 0,04125094 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,03012684 0,04122032 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,03012684 0,04118974 ! regulation of proteolysis GO:0030162 21 21 0,000 0,03012684 0,0411592 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,03012684 0,04112871 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,03012684 0,04109827 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,03012684 0,04106787 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,03154085 0,04296363 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,03154085 0,0429319 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,03154085 0,04290022 ! regulation of ion transport GO:0043269 22 22 0,000 0,03154085 0,04286858 ! odontogenesis GO:0042476 22 22 0,000 0,03154085 0,04283699 ! cell junction organization GO:0034330 23 22 0,000 0,03154085 0,04280545 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,03154085 0,04277395 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,03154085 0,0427425 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,03154085 0,04271109 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,03154085 0,04267973 ! ovulation cycle process GO:0022602 22 22 0,000 0,03154085 0,04264842 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,03154085 0,04261715 ! cell chemotaxis GO:0060326 23 22 0,000 0,03154085 0,04258593 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,03154085 0,04255475 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,03154085 0,04252362 ! male sex differentiation GO:0046661 22 22 0,000 0,03154085 0,04249254 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,03154085 0,0424615 ! biopolymer methylation GO:0043414 22 22 0,000 0,03154085 0,04243051 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,03154085 0,04239956 ! detection of external stimulus GO:0009581 23 22 0,000 0,03154085 0,04236866 ! neuron migration GO:0001764 22 22 0,000 0,03154085 0,0423378 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,03154085 0,04230698 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,03154085 0,04227621 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,03154085 0,04224549 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,03154085 0,04221481 ! aerobic respiration GO:0009060 22 22 0,000 0,03154085 0,04218418 ! cytokine production GO:0001816 22 22 0,000 0,03154085 0,04215359 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,03154085 0,04212304 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,03295301 0,04397712 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,03295301 0,0439453 ! viral infectious cycle GO:0019058 23 23 0,000 0,03295301 0,04391353 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,03295301 0,0438818 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,03295301 0,04385011 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,03295301 0,04381847 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,03295301 0,04378688 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,03295301 0,04375534 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,03295301 0,04372383 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,03295301 0,04369238 ! endocrine system development GO:0035270 23 23 0,000 0,03295301 0,04366097 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,03295301 0,0436296 ! female gonad development GO:0008585 23 23 0,000 0,03295301 0,04359828 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,03295301 0,04356701 ! lipid homeostasis GO:0055088 23 23 0,000 0,03295301 0,04353577 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,03295301 0,04350459 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,03295301 0,04347345 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,03295301 0,04344235 ! cell projection assembly GO:0030031 25 23 0,000 0,03295301 0,0434113 ! mitochondrial transport GO:0006839 24 24 0,000 0,03436332 0,04523686 ! regulation of action potential GO:0001508 24 24 0,000 0,03436332 0,04520457 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,03436332 0,04517233 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,03436332 0,04514013 ! glucose homeostasis GO:0042593 24 24 0,000 0,03436332 0,04510798 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,03436332 0,04507587 ! T cell differentiation GO:0030217 24 24 0,000 0,03436332 0,04504381 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,03436332 0,0450118 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,03436332 0,04497983 ! ovulation cycle GO:0042698 24 24 0,000 0,03436332 0,04494791 ! fertilization GO:0009566 25 24 0,000 0,03436332 0,04491603 ! maintenance of protein location GO:0045185 25 24 0,000 0,03436332 0,0448842 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,03436332 0,04485241 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,03436332 0,04482067 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,03436332 0,04478897 ! glucan metabolic process GO:0044042 25 24 0,000 0,03436332 0,04475731 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,03577178 0,04655889 ! negative regulation of secretion GO:0051048 26 25 0,000 0,03577178 0,04652603 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,03577178 0,04649322 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,03577178 0,04646045 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,03577178 0,04642773 ! cellular component disassembly GO:0022411 26 25 0,000 0,03577178 0,04639506 ! endosome transport GO:0016197 25 25 0,000 0,03577178 0,04636243 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,03577178 0,04632985 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,03577178 0,04629732 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,03577178 0,04626483 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,03577178 0,04623239 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,03577178 0,04619999 ! excretion GO:0007588 25 25 0,000 0,03577178 0,04616763 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,03577178 0,04613533 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,03577178 0,04610306 ! gastrulation GO:0007369 25 25 0,000 0,03577178 0,04607085 ! heart morphogenesis GO:0003007 25 25 0,000 0,03577178 0,04603867 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,03577178 0,04600655 ! regulation of endocytosis GO:0030100 25 25 0,000 0,03577178 0,04597446 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,03577178 0,04594243 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,03577178 0,04591043 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,03577178 0,04587848 ! positive regulation of binding GO:0051099 27 26 0,000 0,03717838 0,04764934 ! positive regulation of defense response GO:0031349 26 26 0,000 0,03717838 0,04761623 ! glycolysis GO:0006096 26 26 0,000 0,03717838 0,04758316 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,03717838 0,04755014 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,03717838 0,04751717 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,03717838 0,04748424 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,03717838 0,04745136 ! cellular defense response GO:0006968 26 26 0,000 0,03717838 0,04741852 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,03717838 0,04738572 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,03717838 0,04735298 ! double-strand break repair GO:0006302 27 26 0,000 0,03717838 0,04732027 ! regulation of protein secretion GO:0050708 26 26 0,000 0,03717838 0,04728762 ! germ cell development GO:0007281 27 26 0,000 0,03717838 0,047255 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,03717838 0,04722244 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,03717838 0,04718992 ! maintenance of location in cell GO:0051651 27 26 0,000 0,03717838 0,04715744 ! synapse organization GO:0050808 26 26 0,000 0,03717838 0,047125 ! chloride transport GO:0006821 27 27 0,000 0,03858314 0,04887198 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,03858314 0,04883841 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,03858314 0,04880489 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,03858314 0,04877142 ! learning or memory GO:0007611 28 27 0,000 0,03858314 0,04873799 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,03858314 0,04870461 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,03858314 0,04867127 ! peptide metabolic process GO:0006518 29 27 0,000 0,03858314 0,04863798 ! activation of caspase activity GO:0006919 27 27 0,000 0,03858314 0,04860473 ! inner ear development GO:0048839 27 27 0,000 0,03858314 0,04857153 ! defense response to bacterium GO:0042742 27 27 0,000 0,03858314 0,04853838 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,03858314 0,04850527 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,03858314 0,04847221 ! cell growth GO:0016049 27 27 0,000 0,03858314 0,04843919 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,03998605 0,0501663 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,03998605 0,05013218 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,03998605 0,05009809 ! carbohydrate transport GO:0008643 28 28 0,000 0,03998605 0,05006406 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,03998605 0,05003007 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,03998605 0,04999613 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,03998605 0,04996224 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,03998605 0,04992839 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,03998605 0,04989458 ! cartilage development GO:0051216 29 28 0,000 0,03998605 0,04986082 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,04138713 0,051573 ! viral reproductive process GO:0022415 29 29 0,000 0,04138713 0,05153816 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,04138713 0,05150336 ! leukocyte migration GO:0050900 30 29 0,000 0,04138713 0,0514686 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,04138713 0,0514339 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,04138713 0,05139924 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,04138713 0,05136463 ! tRNA processing GO:0008033 29 29 0,000 0,04138713 0,05133006 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,04138713 0,05129554 ! adult behavior GO:0030534 30 29 0,000 0,04138713 0,05126107 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,04138713 0,05122664 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,04138713 0,05119226 ! response to UV GO:0009411 29 29 0,000 0,04138713 0,05115793 ! transition metal ion transport GO:0000041 31 30 0,000 0,04278636 0,05285205 ! RNA catabolic process GO:0006401 30 30 0,000 0,04278636 0,05281665 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,04278636 0,05278129 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,04278636 0,05274599 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,04278636 0,05271073 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,04278636 0,05267552 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,04278636 0,05264036 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,04278636 0,05260524 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,04278636 0,05257017 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,04278636 0,05253515 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,04278636 0,05250017 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,04278636 0,05246524 ! response to temperature stimulus GO:0009266 30 30 0,000 0,04278636 0,05243035 ! regulation of ossification GO:0030278 30 30 0,000 0,04278636 0,05239552 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,04278636 0,05236073 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,04278636 0,05232598 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,04278636 0,05229128 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,04278636 0,05225663 ! vesicle organization GO:0016050 30 30 0,000 0,04278636 0,05222202 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,04278636 0,05218746 ! regulation of translational initiation GO:0006446 31 31 0,000 0,04418375 0,05385625 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,04418375 0,05382065 ! membrane fusion GO:0006944 31 31 0,000 0,04418375 0,0537851 ! B cell activation GO:0042113 31 31 0,000 0,04418375 0,0537496 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,04418375 0,05371415 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,04418375 0,05367874 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,04418375 0,05364338 ! ion transmembrane transport GO:0034220 31 31 0,000 0,04418375 0,05360806 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,04418375 0,05357279 ! digestion GO:0007586 31 31 0,000 0,04418375 0,05353757 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,04418375 0,0535024 ! regulation of DNA replication GO:0006275 32 31 0,000 0,04418375 0,05346727 ! regulation of heart contraction GO:0008016 31 31 0,000 0,04418375 0,05343218 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,04418375 0,05339715 ! camera-type eye development GO:0043010 31 31 0,000 0,04418375 0,05336215 ! extracellular matrix organization GO:0030198 31 31 0,000 0,04418375 0,05332721 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,04418375 0,05329231 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,04418375 0,05325745 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,04418375 0,05322265 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,04418375 0,05318788 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,0455793 0,05483202 ! cell redox homeostasis GO:0045454 32 32 0,000 0,0455793 0,05479625 ! muscle fiber development GO:0048747 32 32 0,000 0,0455793 0,05476053 ! glucose catabolic process GO:0006007 32 32 0,000 0,0455793 0,05472486 ! lipid modification GO:0030258 32 32 0,000 0,0455793 0,05468923 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,0455793 0,05465365 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,0455793 0,05461811 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,0455793 0,05458262 ! cell maturation GO:0048469 32 32 0,000 0,0455793 0,05454718 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,0455793 0,05451178 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,0455793 0,05447643 ! kidney development GO:0001822 32 32 0,000 0,0455793 0,05444113 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,0455793 0,05440587 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,0455793 0,05437065 ! maintenance of location GO:0051235 33 32 0,000 0,0455793 0,05433548 ! negative regulation of cell size GO:0045792 33 33 0,000 0,04697303 0,05596075 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,04697303 0,0559246 ! amino acid transport GO:0006865 33 33 0,000 0,04697303 0,0558885 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,04697303 0,05585244 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,04697303 0,05581643 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,04697303 0,05578047 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,04697303 0,05574455 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,04697303 0,05570868 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,04697303 0,05567285 ! regulation of actin filament length GO:0030832 34 34 0,000 0,04836492 0,05728569 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,04836492 0,0572489 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,04836492 0,05721216 ! response to metal ion GO:0010038 34 34 0,000 0,04836492 0,05717546 ! ear development GO:0043583 34 34 0,000 0,04836492 0,05713881 ! muscle cell differentiation GO:0042692 35 34 0,000 0,04836492 0,0571022 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,04836492 0,05706565 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,04836492 0,05702914 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,04836492 0,05699267 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,04836492 0,05695625 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,04836492 0,05691988 ! secondary metabolic process GO:0019748 34 34 0,000 0,04836492 0,05688356 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,04836492 0,05684728 ! viral reproduction GO:0016032 34 34 0,000 0,04836492 0,05681105 ! detection of stimulus GO:0051606 36 34 0,000 0,04836492 0,05677487 ! acute inflammatory response GO:0002526 35 35 0,000 0,04975498 0,05836946 ! regulation of cellular component size GO:0032535 35 35 0,000 0,04975498 0,05833233 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,04975498 0,05829524 ! mesoderm development GO:0007498 35 35 0,000 0,04975498 0,05825821 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,04975498 0,05822122 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,04975498 0,05818428 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,04975498 0,05814738 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,04975498 0,05811053 ! inorganic anion transport GO:0015698 35 35 0,000 0,04975498 0,05807373 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,04975498 0,05803697 ! regulation of immune effector process GO:0002697 35 35 0,000 0,04975498 0,05800027 ! hydrogen transport GO:0006818 36 36 0,000 0,05114321 0,05958087 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,05114321 0,05954323 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,05114321 0,05950564 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,05114321 0,0594681 ! positive regulation of cell migration GO:0030335 36 36 0,000 0,05114321 0,0594306 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,05114321 0,05939315 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,05114321 0,05935575 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,05114321 0,0593184 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,05114321 0,05928109 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,05114321 0,05924383 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,05114321 0,05920662 ! gonad development GO:0008406 36 36 0,000 0,05114321 0,05916945 ! regulation of lipase activity GO:0060191 36 36 0,000 0,05114321 0,05913233 ! activation of immune response GO:0002253 36 36 0,000 0,05114321 0,05909526 ! coagulation GO:0050817 39 36 0,000 0,05114321 0,05905823 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,05252961 0,06062121 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,05252961 0,06058328 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 0,000 0,05252961 0,06054539 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,05252961 0,06050755 ! eye development GO:0001654 37 37 0,000 0,05252961 0,06046976 ! negative regulation of growth GO:0045926 37 37 0,000 0,05252961 0,06043201 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,05252961 0,06039431 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,05252961 0,06035666 ! adaptive immune response GO:0002250 37 37 0,000 0,05252961 0,06031905 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,0539142 0,0618704 ! neurotransmitter transport GO:0006836 40 38 0,000 0,0539142 0,0618319 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,0539142 0,06179345 ! exocytosis GO:0006887 40 38 0,000 0,0539142 0,06175504 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,0539142 0,06171669 ! urogenital system development GO:0001655 38 38 0,000 0,0539142 0,06167838 ! hexose catabolic process GO:0019320 38 38 0,000 0,0539142 0,06164012 ! RNA elongation GO:0006354 38 38 0,000 0,0539142 0,0616019 ! axon guidance GO:0007411 39 38 0,000 0,0539142 0,06156373 ! regulation of neurological system process GO:0031644 38 38 0,000 0,0539142 0,06152561 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,0539142 0,06148754 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,0539142 0,06144952 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,05529696 0,06298659 ! hemostasis GO:0007599 42 39 0,000 0,05529696 0,06294768 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,05529696 0,06290883 ! activation of MAPK activity GO:0000187 39 39 0,000 0,05529696 0,06287002 ! response to unfolded protein GO:0006986 39 39 0,000 0,05529696 0,06283126 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,05529696 0,06279254 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,05529696 0,06275388 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,05529696 0,06271526 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,05529696 0,06267669 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,05529696 0,06263817 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,05529696 0,06259969 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,05529696 0,06256126 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,05529696 0,06252288 ! protein oligomerization GO:0051259 39 39 0,000 0,05529696 0,06248455 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,05529696 0,06244626 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,0566779 0,06396655 ! DNA catabolic process GO:0006308 41 40 0,000 0,0566779 0,0639274 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,0566779 0,0638883 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,0566779 0,06384925 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,05805703 0,06536292 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,05805703 0,06532302 ! amine catabolic process GO:0009310 42 41 0,000 0,05805703 0,06528316 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,05805703 0,06524336 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,05805703 0,0652036 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,05805703 0,06516389 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,05805703 0,06512423 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,05943434 0,06662864 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,05943434 0,06658814 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,05943434 0,06654768 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,05943434 0,06650728 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,05943434 0,06646692 ! protein ubiquitination GO:0016567 43 42 0,000 0,05943434 0,06642661 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,05943434 0,06638636 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,05943434 0,06634615 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,05943434 0,06630599 ! reproductive structure development GO:0048608 43 43 0,000 0,06080984 0,06779947 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,06080984 0,06775848 ! alcohol catabolic process GO:0046164 43 43 0,000 0,06080984 0,06771754 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,06080984 0,06767665 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,06080984 0,06763581 ! humoral immune response GO:0006959 44 44 0,000 0,06218353 0,06912198 ! mRNA transport GO:0051028 44 44 0,000 0,06218353 0,06908031 ! protein import into nucleus GO:0006606 44 44 0,000 0,06218353 0,0690387 ! vitamin metabolic process GO:0006766 44 44 0,000 0,06218353 0,06899713 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,06218353 0,06895562 ! amine biosynthetic process GO:0009309 46 45 0,000 0,0635554 0,07043452 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,0635554 0,07039219 ! regulation of DNA binding GO:0051101 47 45 0,000 0,0635554 0,07034992 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,0635554 0,07030769 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,0635554 0,07026551 ! nuclear import GO:0051170 45 45 0,000 0,0635554 0,07022339 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,0635554 0,07018131 ! protein processing GO:0016485 45 45 0,000 0,0635554 0,07013929 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,06492548 0,07160841 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,06492548 0,07156558 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,06492548 0,07152281 ! regulation of membrane potential GO:0042391 46 46 0,000 0,06492548 0,07148008 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,06629375 0,07294291 ! regulation of blood pressure GO:0008217 48 47 0,000 0,06629375 0,07289939 ! sex differentiation GO:0007548 47 47 0,000 0,06629375 0,07285592 ! amine transport GO:0015837 47 47 0,000 0,06629375 0,0728125 ! rhythmic process GO:0048511 47 47 0,000 0,06629375 0,07276913 ! regulation of catabolic process GO:0009894 48 47 0,000 0,06629375 0,07272582 ! calcium ion transport GO:0006816 48 48 0,000 0,06766021 0,07418071 ! actin filament organization GO:0007015 50 48 0,000 0,06766021 0,0741366 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,06766021 0,07409255 ! protein localization in nucleus GO:0034504 48 48 0,000 0,06766021 0,07404856 ! DNA recombination GO:0006310 48 48 0,000 0,06766021 0,07400461 ! leukocyte differentiation GO:0002521 50 49 0,000 0,06902488 0,07545246 ! ossification GO:0001503 50 49 0,000 0,06902488 0,07540773 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,06902488 0,07536306 ! cell cycle arrest GO:0007050 49 49 0,000 0,06902488 0,07531844 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,06902488 0,07527387 ! divalent metal ion transport GO:0070838 49 49 0,000 0,06902488 0,07522936 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,06902488 0,0751849 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,06902488 0,07514049 ! response to bacterium GO:0009617 50 49 0,000 0,06902488 0,07509613 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,06902488 0,07505183 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,06902488 0,07500758 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,06902488 0,07496338 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,07038775 0,07639848 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,07038775 0,07635351 ! negative regulation of transport GO:0051051 51 50 0,000 0,07038775 0,0763086 ! chromatin assembly GO:0031497 50 50 0,000 0,07038775 0,07626374 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 0,000 0,07038775 0,07621893 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,07038775 0,07617417 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,07038775 0,07612947 ! transcription initiation GO:0006352 50 50 0,000 0,07038775 0,07608482 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,07038775 0,07604022 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,07174882 0,07746518 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,07174882 0,07741983 ! positive regulation of immune response GO:0050778 51 51 0,000 0,07174882 0,07737453 ! rRNA metabolic process GO:0016072 51 51 0,000 0,07174882 0,07732928 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,07174882 0,07728409 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,07174882 0,07723894 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,07174882 0,07719385 ! protein maturation GO:0051604 51 51 0,000 0,07174882 0,07714882 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,0731081 0,07856456 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,0731081 0,07851878 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,0731081 0,07847305 ! response to light stimulus GO:0009416 53 52 0,000 0,0731081 0,07842737 ! sodium ion transport GO:0006814 53 53 0,000 0,07446558 0,07983715 ! tRNA metabolic process GO:0006399 53 53 0,000 0,07446558 0,07979074 ! response to hypoxia GO:0001666 53 53 0,000 0,07446558 0,07974437 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,07446558 0,07969807 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,07446558 0,07965181 ! regulation of T cell activation GO:0050863 53 53 0,000 0,07446558 0,07960561 ! regulation of protein transport GO:0051223 53 53 0,000 0,07446558 0,07955946 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,07582128 0,08096096 ! response to oxygen levels GO:0070482 55 54 0,000 0,07582128 0,08091408 ! hormone metabolic process GO:0042445 55 54 0,000 0,07582128 0,08086726 ! sulfur metabolic process GO:0006790 55 54 0,000 0,07582128 0,08082048 ! nucleosome organization GO:0034728 55 55 0,000 0,07717519 0,08221611 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,07717519 0,08216862 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,07717519 0,08212117 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,07717519 0,08207379 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,07852731 0,08346357 ! reproductive developmental process GO:0003006 56 56 0,000 0,07852731 0,08341547 ! extracellular structure organization GO:0043062 56 56 0,000 0,07852731 0,08336742 ! regulation of binding GO:0051098 60 57 0,000 0,07987765 0,08475217 ! ATP metabolic process GO:0046034 57 57 0,000 0,07987765 0,0847034 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,07987765 0,0846547 ! regulation of protein localization GO:0032880 58 57 0,000 0,07987765 0,08460604 ! innate immune response GO:0045087 58 58 0,000 0,08122621 0,08598502 ! dephosphorylation GO:0016311 60 59 0,000 0,08257299 0,08736052 ! carboxylic acid transport GO:0046942 59 59 0,000 0,08257299 0,0873104 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,08257299 0,08726034 ! sterol metabolic process GO:0016125 59 59 0,000 0,08257299 0,08721033 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,08257299 0,08716038 ! protein localization in organelle GO:0033365 59 59 0,000 0,08257299 0,08711049 ! immune effector process GO:0002252 59 59 0,000 0,08257299 0,08706066 ! potassium ion transport GO:0006813 60 60 0,000 0,083918 0,08842817 ! protein polymerization GO:0051258 65 60 0,000 0,083918 0,08837764 ! cellular respiration GO:0045333 62 61 0,000 0,08526123 0,08974097 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,08526123 0,08968975 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,08526123 0,08963859 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,08526123 0,08958748 ! lipid transport GO:0006869 62 62 0,000 0,08660268 0,09094515 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,08660268 0,09089336 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,08660268 0,09084163 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 0,000 0,08660268 0,09078996 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,08660268 0,09073834 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,08660268 0,09068679 ! regulation of secretion GO:0051046 65 63 0,000 0,08794237 0,09203736 ! glucose metabolic process GO:0006006 63 63 0,000 0,08794237 0,09198512 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,08794237 0,09193295 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,08794237 0,09188083 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,08928028 0,09322582 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,08928028 0,09317303 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,08928028 0,0931203 ! anion transport GO:0006820 65 65 0,000 0,09061643 0,09446046 ! regulation of hormone levels GO:0010817 66 65 0,000 0,09061643 0,09440706 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,09195082 0,09574314 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,09195082 0,09568908 ! DNA packaging GO:0006323 66 66 0,000 0,09195082 0,09563508 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,09195082 0,09558114 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,09195082 0,09552726 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,09328344 0,09685712 ! muscle contraction GO:0006936 67 67 0,000 0,09328344 0,09680258 ! striated muscle tissue development GO:0014706 69 67 0,000 0,09328344 0,09674811 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,09328344 0,09669369 ! response to radiation GO:0009314 70 68 0,000 0,0946143 0,09801808 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,0946143 0,09796301 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,0946143 0,09790801 ! sensory perception of sound GO:0007605 71 69 0,000 0,09594341 0,09922767 GO:0050954|sensory perception of mechanical stimulus, ! response to nutrient levels GO:0031667 69 69 0,000 0,09594341 0,09917202 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,09594341 0,09911643 ! positive regulation of transport GO:0051050 71 70 0,000 0,09727076 0,10043138 ! wound healing GO:0042060 74 70 0,000 0,09727076 0,10037514 ! muscle tissue development GO:0060537 72 70 0,000 0,09727076 0,10031897 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,09727076 0,10026287 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,09859635 0,10157243 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,09859635 0,10151568 ! regulation of cell migration GO:0030334 71 71 0,000 0,09859635 0,101459 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,09859635 0,10140238 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 0,000 0,09859635 0,10134583 ! secretion by cell GO:0032940 75 72 0,000 0,09992019 0,10264934 ! muscle system process GO:0003012 72 72 0,000 0,09992019 0,10259215 ! sensory organ development GO:0007423 72 72 0,000 0,09992019 0,10253503 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,09992019 0,10247797 ! regulation of cytokine production GO:0001817 72 72 0,000 0,09992019 0,10242098 ! electron transport chain GO:0022900 75 74 0,000 0,10256263 0,10507111 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,10256263 0,10501273 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,10388122 0,10630377 ! response to oxidative stress GO:0006979 76 75 0,000 0,10388122 0,10624478 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,10388122 0,10618585 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,10519808 0,10747232 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,10651319 0,10875557 ! microtubule-based movement GO:0007018 82 78 0,000 0,10782656 0,11003563 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,10782656 0,10997474 ! metal ion homeostasis GO:0055065 78 78 0,000 0,10782656 0,10991391 ! regulation of immune response GO:0050776 78 78 0,000 0,10782656 0,10985315 ! regulation of locomotion GO:0040012 79 79 0,000 0,10913819 0,11112801 ! regulation of cell motion GO:0051270 79 79 0,000 0,10913819 0,11106664 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,11044809 0,11233766 ! MAPKKK cascade GO:0000165 82 81 0,000 0,11175626 0,11360551 ! lymphocyte activation GO:0046649 82 81 0,000 0,11175626 0,11354288 ! lipid catabolic process GO:0016042 82 81 0,000 0,11175626 0,11348032 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,11436739 0,11606779 ! ncRNA processing GO:0034470 83 83 0,000 0,11436739 0,11600391 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,11567037 0,117261 ! regulation of cellular localization GO:0060341 86 85 0,000 0,11697162 0,11851495 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,11697162 0,11844983 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,11697162 0,11838479 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,11827115 0,11963432 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,11827115 0,11956869 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,11827115 0,11950314 ! male gamete generation GO:0048232 90 88 0,000 0,12086504 0,12205713 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,12086504 0,12199029 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,12086504 0,12192352 ! chemotaxis GO:0006935 90 89 0,000 0,12215941 0,12316181 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,12215941 0,12309447 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,124743 0,12562915 ! DNA replication GO:0006260 91 91 0,000 0,124743 0,12556054 ! visual perception GO:0007601 93 92 0,000 0,12603223 0,12678897 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,12603223 0,1267198 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,12603223 0,12665071 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,12603223 0,12658169 ! regulation of response to stress GO:0080134 97 94 0,000 0,12860556 0,12909588 ! cofactor metabolic process GO:0051186 95 94 0,000 0,12860556 0,12902561 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,13373177 0,13409557 ! blood circulation GO:0008015 99 98 0,000 0,13373177 0,13402265 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,13373177 0,13394981 ! muscle organ development GO:0007517 102 100 0,000 0,13628468 0,13643274 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,13628468 0,13635867 ! hemopoiesis GO:0030097 104 100 0,000 0,13628468 0,13628468