pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/3678-4-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein refolding GO:0042026 13 6 2,000 1,036E-08 2,458E-05 ! outer mitochondrial membrane organization GO:0007008 12 7 2,000 1,812E-08 2,15E-05 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! chaperone-mediated protein complex assembly GO:0051131 12 8 2,000 2,897E-08 2,292E-05 ! response to unfolded protein GO:0006986 113 80 3,000 5,551E-07 3,293E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 2,000 5,861E-07 2,782E-04 ! response to protein stimulus GO:0051789 127 85 3,000 7,088E-07 2,803E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 2,000 1,038E-06 3,52E-04 ! mitochondrial membrane organization GO:0007006 42 25 2,000 1,179E-06 3,498E-04 ! mitochondrial transport GO:0006839 66 43 2,000 6,268E-06 1,653E-03 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 6,867E-06 1,629E-03 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 6,867E-06 1,481E-03 ! short-chain fatty acid metabolic process GO:0046459 8 5 1,000 6,867E-06 1,358E-03 ! galactolipid metabolic process GO:0019374 8 5 1,000 6,867E-06 1,253E-03 GO:0006681|galactosylceramide metabolic process, ! positive regulation of cell cycle GO:0045787 83 45 2,000 7,199E-06 1,22E-03 ! wound healing, spreading of epidermal cells GO:0035313 10 6 1,000 1,029E-05 1,629E-03 ! positive regulation of Rho GTPase activity GO:0032321 12 6 1,000 1,029E-05 1,527E-03 ! establishment of chromosome localization GO:0051303 10 6 1,000 1,029E-05 1,437E-03 GO:0050000|chromosome localization, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,441E-05 1,899E-03 ! positive regulation of mitotic cell cycle GO:0045931 13 7 1,000 1,441E-05 1,799E-03 ! spindle checkpoint GO:0031577 20 7 1,000 1,441E-05 1,709E-03 ! glycosylceramide metabolic process GO:0006677 10 7 1,000 1,441E-05 1,628E-03 ! neurotransmitter catabolic process GO:0042135 16 8 1,000 1,92E-05 2,071E-03 ! regulation of focal adhesion formation GO:0051893 17 8 1,000 1,92E-05 1,981E-03 ! succinate metabolic process GO:0006105 16 9 1,000 2,467E-05 2,439E-03 ! regulation of exit from mitosis GO:0007096 12 9 1,000 2,467E-05 2,342E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 1,000 3,082E-05 2,813E-03 ! regulation of stress fiber formation GO:0051492 24 10 1,000 3,082E-05 2,709E-03 ! protein homotetramerization GO:0051289 20 10 1,000 3,082E-05 2,612E-03 ! positive regulation of Ras GTPase activity GO:0032320 24 10 1,000 3,082E-05 2,522E-03 ! regulation of phosphatase activity GO:0010921 23 11 1,000 3,765E-05 2,978E-03 ! thymus development GO:0048538 19 11 1,000 3,765E-05 2,882E-03 ! regulation of actin filament bundle formation GO:0032231 25 11 1,000 3,765E-05 2,792E-03 ! mitochondrion organization GO:0007005 127 78 2,000 3,793E-05 2,728E-03 ! positive regulation of GTPase activity GO:0043547 29 12 1,000 4,516E-05 3,152E-03 ! regulation of Rho GTPase activity GO:0032319 22 12 1,000 4,516E-05 3,062E-03 ! T cell homeostasis GO:0043029 22 12 1,000 4,516E-05 2,977E-03 ! interphase of mitotic cell cycle GO:0051329 166 87 2,000 5,26E-05 3,373E-03 ! interphase GO:0051325 169 89 2,000 5,629E-05 3,515E-03 ! regulation of protein ubiquitination GO:0031396 20 14 1,000 6,221E-05 3,785E-03 ! glutamate metabolic process GO:0006536 21 14 1,000 6,221E-05 3,69E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 6,221E-05 3,6E-03 ! lymphocyte homeostasis GO:0002260 29 15 1,000 7,174E-05 4,053E-03 ! cellular amino acid derivative catabolic process GO:0042219 31 16 1,000 8,195E-05 4,522E-03 ! heterophilic cell adhesion GO:0007157 38 17 1,000 9,283E-05 5,006E-03 ! negative regulation of peptidase activity GO:0010466 25 17 1,000 9,283E-05 4,895E-03 ! cell-substrate junction assembly GO:0007044 45 18 1,000 1,044E-04 5,384E-03 ! cellular response to unfolded protein GO:0034620 24 18 1,000 1,044E-04 5,27E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 38 18 1,000 1,044E-04 5,16E-03 ! aromatic compound catabolic process GO:0019439 26 18 1,000 1,044E-04 5,055E-03 ! memory GO:0007613 28 19 1,000 1,166E-04 5,534E-03 ! negative regulation of translation GO:0017148 28 20 1,000 1,295E-04 6,025E-03 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 1,000 1,43E-04 6,528E-03 ! glutamine metabolic process GO:0006541 29 21 1,000 1,43E-04 6,405E-03 ! neurotransmitter metabolic process GO:0042133 36 21 1,000 1,43E-04 6,286E-03 ! glycosphingolipid metabolic process GO:0006687 35 21 1,000 1,43E-04 6,172E-03 ! neural tube closure GO:0001843 35 22 1,000 1,573E-04 6,664E-03 GO:0060606|tube closure, ! protein tetramerization GO:0051262 43 22 1,000 1,573E-04 6,547E-03 ! dicarboxylic acid metabolic process GO:0043648 36 23 1,000 1,722E-04 7,044E-03 ! tube lumen formation GO:0035148 37 23 1,000 1,722E-04 6,925E-03 ! glycolipid metabolic process GO:0006664 39 23 1,000 1,722E-04 6,809E-03 ! leukocyte adhesion GO:0007159 49 24 1,000 1,877E-04 7,303E-03 ! response to endoplasmic reticulum stress GO:0034976 32 24 1,000 1,877E-04 7,185E-03 ! primary neural tube formation GO:0014020 37 24 1,000 1,877E-04 7,071E-03 ! regulation of cell-matrix adhesion GO:0001952 57 25 1,000 2,039E-04 7,562E-03 GO:0010810|regulation of cell-substrate adhesion, ! leukocyte homeostasis GO:0001776 40 25 1,000 2,039E-04 7,445E-03 ! positive regulation of nuclear division GO:0051785 41 25 1,000 2,039E-04 7,333E-03 GO:0045840|positive regulation of mitosis, ! ER-nuclear signaling pathway GO:0006984 33 26 1,000 2,208E-04 7,821E-03 ! fat cell differentiation GO:0045444 41 27 1,000 2,384E-04 8,318E-03 ! glutathione metabolic process GO:0006749 35 27 1,000 2,384E-04 8,198E-03 ! negative regulation of protein modification process GO:0031400 56 28 1,000 2,566E-04 8,698E-03 ! positive regulation of cell adhesion GO:0045785 54 29 1,000 2,754E-04 9,206E-03 ! neural tube formation GO:0001841 46 29 1,000 2,754E-04 9,078E-03 ! cell junction assembly GO:0034329 65 30 1,000 2,95E-04 9,589E-03 ! ceramide metabolic process GO:0006672 47 30 1,000 2,95E-04 9,459E-03 ! fatty acid catabolic process GO:0009062 45 30 1,000 2,95E-04 9,333E-03 ! post-embryonic development GO:0009791 50 31 1,000 3,152E-04 9,84E-03 ! embryonic epithelial tube formation GO:0001838 50 31 1,000 3,152E-04 9,713E-03 ! sphingoid metabolic process GO:0046519 51 33 1,000 3,575E-04 0,01087618 ! cell junction organization GO:0034330 72 35 1,000 4,025E-04 0,012089 ! negative regulation of hydrolase activity GO:0051346 56 35 1,000 4,025E-04 0,01193789 ! cytokinesis GO:0000910 57 35 1,000 4,025E-04 0,0117905 ! protein homooligomerization GO:0051260 59 35 1,000 4,025E-04 0,01164672 ! neural tube development GO:0021915 58 39 1,000 5,002E-04 0,01430104 ! RNA export from nucleus GO:0006405 57 41 1,000 5,53E-04 0,0156216 ! morphogenesis of embryonic epithelium GO:0016331 69 42 1,000 5,803E-04 0,01620156 ! response to calcium ion GO:0051592 65 43 1,000 6,083E-04 0,01678587 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 1,000 6,37E-04 0,01737433 ! peptide metabolic process GO:0006518 64 44 1,000 6,37E-04 0,0171769 ! response to insulin stimulus GO:0032868 71 45 1,000 6,663E-04 0,01776492 ! epithelial tube morphogenesis GO:0060562 73 46 1,000 6,962E-04 0,01835683 ! response to UV GO:0009411 79 47 1,000 7,268E-04 0,01895248 ! respiratory electron transport chain GO:0022904 63 49 1,000 7,899E-04 0,02037346 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 1,000 9,237E-04 0,02356887 ! glutamine family amino acid metabolic process GO:0009064 71 53 1,000 9,237E-04 0,02331814 ! establishment of organelle localization GO:0051656 91 54 1,000 9,587E-04 0,02394806 ! regulation of mitosis GO:0007088 91 54 1,000 9,587E-04 0,0236986 GO:0051783|regulation of nuclear division, ! sphingolipid metabolic process GO:0006665 80 54 1,000 9,587E-04 0,02345429 ! integrin-mediated signaling pathway GO:0007229 93 55 1,000 9,944E-04 0,0240789 ! positive regulation of organelle organization GO:0010638 95 56 1,000 1,031E-03 0,02470607 ! regulation of neurotransmitter levels GO:0001505 85 57 1,000 1,068E-03 0,02533569 ! nuclear export GO:0051168 85 57 1,000 1,068E-03 0,02508485 ! membrane lipid metabolic process GO:0006643 88 58 1,000 1,105E-03 0,0257131 ! response to peptide hormone stimulus GO:0043434 97 60 1,000 1,182E-03 0,0272384 ! organelle localization GO:0051640 105 65 1,000 1,386E-03 0,03162168 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 1,000 1,428E-03 0,03228307 ! protein oligomerization GO:0051259 109 66 1,000 1,428E-03 0,03197852 ! cell cycle checkpoint GO:0000075 123 67 1,000 1,472E-03 0,03263802 ! regulation of caspase activity GO:0043281 104 68 1,000 1,516E-03 0,03329896 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 1,516E-03 0,03299346 ! regulation of endopeptidase activity GO:0052548 106 70 1,000 1,605E-03 0,03462494 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 1,000 1,605E-03 0,034313 ! regulation of actin cytoskeleton organization GO:0032956 120 72 1,000 1,697E-03 0,03595599 ! homeostasis of number of cells GO:0048872 109 72 1,000 1,697E-03 0,0356378 ! learning or memory GO:0007611 132 73 1,000 1,744E-03 0,03630203 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 1,000 1,744E-03 0,03598636 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 1,000 1,744E-03 0,03567613 ! regulation of actin filament-based process GO:0032970 122 74 1,000 1,792E-03 0,03633549 ! regulation of Rho protein signal transduction GO:0035023 126 74 1,000 1,792E-03 0,03602756 ! regulation of peptidase activity GO:0052547 113 75 1,000 1,84E-03 0,03668515 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 1,84E-03 0,03637944 ! response to metal ion GO:0010038 114 76 1,000 1,888E-03 0,03703529 ! regulation of Ras GTPase activity GO:0032318 125 76 1,000 1,888E-03 0,03673172 ! positive regulation of ligase activity GO:0051351 114 76 1,000 1,888E-03 0,03643309 ! cellular lipid catabolic process GO:0044242 117 77 1,000 1,938E-03 0,03708437 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 1,938E-03 0,03678769 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 1,000 2,038E-03 0,03839046 ! tube morphogenesis GO:0035239 140 80 1,000 2,09E-03 0,03904519 ! protein ubiquitination GO:0016567 135 80 1,000 2,09E-03 0,03874015 ! response to inorganic substance GO:0010035 127 81 1,000 2,141E-03 0,03939322 ! regulation of ligase activity GO:0051340 129 82 1,000 2,194E-03 0,04004734 ! positive regulation of protein modification process GO:0031401 126 83 1,000 2,247E-03 0,04070247 ! regulation of cell cycle process GO:0010564 139 83 1,000 2,247E-03 0,04039412 ! cellular respiration GO:0045333 119 85 1,000 2,355E-03 0,04201562 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 1,000 2,355E-03 0,04170207 GO:0010498|proteasomal protein catabolic process, ! ossification GO:0001503 150 89 1,000 2,578E-03 0,04531388 GO:0060348|bone development, ! regulation of GTPase activity GO:0043087 149 90 1,000 2,635E-03 0,04597989 ! carboxylic acid catabolic process GO:0046395 132 91 1,000 2,693E-03 0,04664657 GO:0016054|organic acid catabolic process, ! regulation of cell adhesion GO:0030155 187 94 1,000 2,87E-03 0,04935536 ! protein modification by small protein conjugation GO:0032446 153 96 1,000 2,991E-03 0,05106775 ! Wnt receptor signaling pathway GO:0016055 161 98 1,000 3,115E-03 0,05279596 ! electron transport chain GO:0022900 135 99 1,000 3,177E-03 0,05347554 ! glycerophospholipid metabolic process GO:0006650 143 99 1,000 3,177E-03 0,05309895 ! sulfur metabolic process GO:0006790 136 99 1,000 3,177E-03 0,05272763 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 4,267E-03 0,07031763 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 4,267E-03 0,06983268 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 4,267E-03 0,06935437 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 4,267E-03 0,06888257 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 4,267E-03 0,06841715 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,267E-03 0,06795798 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 4,267E-03 0,06750492 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 4,267E-03 0,06705787 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 4,267E-03 0,0666167 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 4,267E-03 0,0661813 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 4,267E-03 0,06575155 ! response to oxygen radical GO:0000305 11 5 0,000 4,267E-03 0,06532734 ! negative regulation of bone resorption GO:0045779 11 5 0,000 4,267E-03 0,06490858 ! myoblast cell fate commitment GO:0048625 8 5 0,000 4,267E-03 0,06449515 ! nucleotide-sugar transport GO:0015780 8 5 0,000 4,267E-03 0,06408695 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 4,267E-03 0,06368389 ! regulation of interferon-beta production GO:0032648 5 5 0,000 4,267E-03 0,06328586 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 4,267E-03 0,06289278 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 4,267E-03 0,06250456 ! female meiosis GO:0007143 8 5 0,000 4,267E-03 0,06212109 ! nose development GO:0043584 10 5 0,000 4,267E-03 0,06174231 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 4,267E-03 0,06136811 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 4,267E-03 0,06099842 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 4,267E-03 0,06063316 ! cobalt ion transport GO:0006824 9 5 0,000 4,267E-03 0,06027225 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 4,267E-03 0,05991561 ! SMAD protein complex assembly GO:0007183 10 5 0,000 4,267E-03 0,05956317 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 4,267E-03 0,05921484 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 4,267E-03 0,05887057 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 4,267E-03 0,05853028 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 4,267E-03 0,0581939 ! adaptation of signaling pathway GO:0022401 9 5 0,000 4,267E-03 0,05786136 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 4,267E-03 0,0575326 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,267E-03 0,05720756 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 4,267E-03 0,05688617 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,267E-03 0,05656837 ! negative regulation of histone modification GO:0031057 7 5 0,000 4,267E-03 0,0562541 ! malate metabolic process GO:0006108 8 5 0,000 4,267E-03 0,05594331 ! positive regulation of histone modification GO:0031058 6 5 0,000 4,267E-03 0,05563592 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 4,267E-03 0,0553319 ! clathrin coat assembly GO:0048268 11 5 0,000 4,267E-03 0,05503119 ! Notch receptor processing GO:0007220 8 5 0,000 4,267E-03 0,05473372 ! phototransduction, visible light GO:0007603 7 5 0,000 4,267E-03 0,05443945 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,267E-03 0,05414833 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 4,267E-03 0,05386031 ! mating behavior GO:0007617 6 5 0,000 4,267E-03 0,05357533 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 4,267E-03 0,05329336 ! copulation GO:0007620 8 5 0,000 4,267E-03 0,05301434 ! protein maturation by protein folding GO:0022417 13 5 0,000 4,267E-03 0,05273822 ! embryonic hemopoiesis GO:0035162 13 5 0,000 4,267E-03 0,05246497 ! regulation of potassium ion transport GO:0043266 9 5 0,000 4,267E-03 0,05219453 ! apoptotic cell clearance GO:0043277 14 5 0,000 4,267E-03 0,05192686 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 4,267E-03 0,05166193 ! lipoprotein particle clearance GO:0034381 9 5 0,000 4,267E-03 0,05139969 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 4,267E-03 0,05114009 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 4,267E-03 0,05088311 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 4,267E-03 0,05062869 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 4,267E-03 0,05037681 ! response to axon injury GO:0048678 8 5 0,000 4,267E-03 0,05012742 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,267E-03 0,04988048 ! response to protozoan GO:0001562 10 5 0,000 4,267E-03 0,04963597 ! negative regulation of heart contraction GO:0045822 12 5 0,000 4,267E-03 0,04939385 ! lymph vessel development GO:0001945 8 5 0,000 4,267E-03 0,04915407 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 4,267E-03 0,04891661 ! endochondral ossification GO:0001958 13 5 0,000 4,267E-03 0,04868143 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 4,267E-03 0,04844851 ! single strand break repair GO:0000012 5 5 0,000 4,267E-03 0,0482178 ! parathyroid gland development GO:0060017 8 5 0,000 4,267E-03 0,04798928 ! anagen GO:0042640 7 5 0,000 4,267E-03 0,04776292 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 4,267E-03 0,04753868 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 4,267E-03 0,04731653 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 4,267E-03 0,04709646 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 4,267E-03 0,04687842 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 4,267E-03 0,04666239 ! smooth muscle tissue development GO:0048745 14 5 0,000 4,267E-03 0,04644834 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,267E-03 0,04623625 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 4,267E-03 0,04602608 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 4,267E-03 0,04581782 ! cardiac muscle fiber development GO:0048739 8 5 0,000 4,267E-03 0,04561143 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,267E-03 0,0454069 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 4,267E-03 0,04520419 ! neutrophil mediated immunity GO:0002446 6 5 0,000 4,267E-03 0,04500328 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 4,267E-03 0,04480415 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 4,267E-03 0,04460678 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 4,267E-03 0,04441113 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 4,267E-03 0,0442172 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 4,267E-03 0,04402495 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 4,267E-03 0,04383436 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 4,267E-03 0,04364542 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 4,267E-03 0,0434581 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 4,267E-03 0,04327239 ! tyrosine catabolic process GO:0006572 7 5 0,000 4,267E-03 0,04308825 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 4,267E-03 0,04290567 ! proline biosynthetic process GO:0006561 6 5 0,000 4,267E-03 0,04272463 ! L-serine biosynthetic process GO:0006564 6 5 0,000 4,267E-03 0,04254512 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,267E-03 0,04236711 ! polyol catabolic process GO:0046174 7 5 0,000 4,267E-03 0,04219058 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 4,267E-03 0,04201551 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,267E-03 0,04184189 ! sister chromatid cohesion GO:0007062 10 5 0,000 4,267E-03 0,0416697 ! response to ATP GO:0033198 6 5 0,000 4,267E-03 0,04149893 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 4,267E-03 0,04132954 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 4,267E-03 0,04116154 ! neutrophil activation GO:0042119 6 5 0,000 4,267E-03 0,04099489 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 4,267E-03 0,04082959 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 4,267E-03 0,04066562 ! response to food GO:0032094 5 5 0,000 4,267E-03 0,04050295 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 4,267E-03 0,04034159 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 4,267E-03 0,0401815 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 4,267E-03 0,04002268 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,267E-03 0,03986511 ! paraxial mesoderm development GO:0048339 9 5 0,000 4,267E-03 0,03970878 ! forebrain neuron development GO:0021884 7 5 0,000 4,267E-03 0,03955367 ! melanosome organization GO:0032438 7 5 0,000 4,267E-03 0,03939976 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 4,267E-03 0,03924705 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 4,267E-03 0,03909551 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 4,267E-03 0,03894515 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 4,267E-03 0,03879593 ! mesodermal cell fate determination GO:0007500 7 5 0,000 4,267E-03 0,03864786 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,267E-03 0,03850091 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 4,267E-03 0,03835507 ! nucleoside salvage GO:0043174 7 5 0,000 4,267E-03 0,03821033 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 4,267E-03 0,03806669 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 4,267E-03 0,03792411 ! negative regulation of platelet activation GO:0010544 8 5 0,000 4,267E-03 0,03778261 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 4,267E-03 0,03764215 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,267E-03 0,03750273 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 4,267E-03 0,03736435 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 4,267E-03 0,03722698 ! early endosome to late endosome transport GO:0045022 11 5 0,000 4,267E-03 0,03709062 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 4,267E-03 0,03695525 ! depyrimidination GO:0045008 8 5 0,000 4,267E-03 0,03682087 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,267E-03 0,03668746 ! 5S class rRNA transcription GO:0042791 8 5 0,000 4,267E-03 0,03655501 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 4,267E-03 0,03642352 ! neuronal ion channel clustering GO:0045161 8 5 0,000 4,267E-03 0,03629297 ! sodium ion homeostasis GO:0055078 6 5 0,000 4,267E-03 0,03616335 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 4,267E-03 0,03603466 ! monocyte differentiation GO:0030224 7 5 0,000 4,267E-03 0,03590687 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 4,267E-03 0,03577999 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 4,267E-03 0,03565401 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 4,267E-03 0,03552891 ! response to UV-C GO:0010225 7 5 0,000 4,267E-03 0,03540468 ! protein targeting to vacuole GO:0006623 6 5 0,000 4,267E-03 0,03528132 ! activated T cell proliferation GO:0050798 7 5 0,000 4,267E-03 0,03515881 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 4,267E-03 0,03503716 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 4,267E-03 0,03491634 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 4,267E-03 0,03479635 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 4,267E-03 0,03467719 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 4,267E-03 0,03455883 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 4,267E-03 0,03444129 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 4,267E-03 0,03432454 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 4,267E-03 0,03420858 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 4,267E-03 0,03409339 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 4,267E-03 0,03397899 ! response to cadmium ion GO:0046686 8 5 0,000 4,267E-03 0,03386535 ! melanosome transport GO:0032402 8 5 0,000 4,267E-03 0,03375246 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 4,267E-03 0,03364033 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 4,267E-03 0,03352893 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 4,267E-03 0,03341828 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 4,267E-03 0,03330835 ! positive T cell selection GO:0043368 10 5 0,000 4,267E-03 0,03319914 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 4,267E-03 0,03309065 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 4,267E-03 0,03298286 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 4,267E-03 0,03287577 ! ribosomal subunit assembly GO:0042257 5 5 0,000 4,267E-03 0,03276938 ! base conversion or substitution editing GO:0016553 6 5 0,000 4,267E-03 0,03266367 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 4,267E-03 0,03255864 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 4,267E-03 0,03245429 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 4,267E-03 0,0323506 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 4,267E-03 0,03224757 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 4,267E-03 0,0321452 ! histone demethylation GO:0016577 10 5 0,000 4,267E-03 0,03204348 ! mitotic recombination GO:0006312 10 5 0,000 4,267E-03 0,03194239 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 4,267E-03 0,03184194 ! regulation of sterol transport GO:0032371 7 5 0,000 4,267E-03 0,03174213 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 4,267E-03 0,03164293 ! sympathetic nervous system development GO:0048485 13 5 0,000 4,267E-03 0,03154436 ! enteric nervous system development GO:0048484 9 5 0,000 4,267E-03 0,03144639 ! oxygen homeostasis GO:0032364 8 5 0,000 4,267E-03 0,03134903 ! establishment of planar polarity GO:0001736 7 5 0,000 4,267E-03 0,03125228 ! lymphocyte costimulation GO:0031294 12 5 0,000 4,267E-03 0,03115612 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 4,267E-03 0,03106055 ! transcription termination GO:0006353 8 5 0,000 4,267E-03 0,03096556 ! plasminogen activation GO:0031639 5 5 0,000 4,267E-03 0,03087115 ! B cell homeostasis GO:0001782 12 5 0,000 4,267E-03 0,03077732 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 4,267E-03 0,03068406 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 4,267E-03 0,03059135 ! regulation of hair follicle development GO:0051797 9 5 0,000 4,267E-03 0,03049921 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 4,267E-03 0,03040762 ! apical protein localization GO:0045176 8 5 0,000 4,267E-03 0,03031658 ! definitive hemopoiesis GO:0060216 5 5 0,000 4,267E-03 0,03022608 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 4,267E-03 0,03013613 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 4,267E-03 0,0300467 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 4,267E-03 0,02995781 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 4,267E-03 0,02986943 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 4,267E-03 0,02978158 ! regulation of centrosome duplication GO:0010824 6 5 0,000 4,267E-03 0,02969425 ! disaccharide metabolic process GO:0005984 9 5 0,000 4,267E-03 0,02960742 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,267E-03 0,0295211 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 4,267E-03 0,02943529 ! determination of adult lifespan GO:0008340 8 5 0,000 4,267E-03 0,02934997 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 4,267E-03 0,02926514 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 4,267E-03 0,0291808 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 4,267E-03 0,02909695 ! T cell activation during immune response GO:0002286 9 5 0,000 4,267E-03 0,02901358 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 4,267E-03 0,02893068 ! negative regulation of lipase activity GO:0060192 7 5 0,000 4,267E-03 0,02884826 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 4,267E-03 0,0287663 ! neural plate development GO:0001840 7 5 0,000 4,267E-03 0,02868481 ! regulation of sensory perception GO:0051931 6 5 0,000 4,267E-03 0,02860378 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 4,267E-03 0,02852321 ! regulation of histone acetylation GO:0035065 7 5 0,000 4,267E-03 0,02844309 ! sensory cilium assembly GO:0035058 6 5 0,000 4,267E-03 0,02836341 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 4,267E-03 0,02828419 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 4,267E-03 0,0282054 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,267E-03 0,02812705 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 4,267E-03 0,02804914 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 4,267E-03 0,02797165 ! receptor biosynthetic process GO:0032800 6 5 0,000 4,267E-03 0,0278946 ! penetration of zona pellucida GO:0007341 9 5 0,000 4,267E-03 0,02781796 ! drug metabolic process GO:0017144 5 5 0,000 4,267E-03 0,02774175 ! protein amino acid prenylation GO:0018346 9 5 0,000 4,267E-03 0,02766595 ! organ regeneration GO:0031100 7 5 0,000 4,267E-03 0,02759057 ! carnitine metabolic process GO:0009437 5 5 0,000 4,267E-03 0,02751559 GO:0006577|betaine metabolic process, ! tRNA transcription GO:0009304 11 6 0,000 5,118E-03 0,03291599 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 5,118E-03 0,03282703 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 5,118E-03 0,03273854 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 5,118E-03 0,03265054 ! regulation of helicase activity GO:0051095 11 6 0,000 5,118E-03 0,032563 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 5,118E-03 0,03247594 ! sleep GO:0030431 13 6 0,000 5,118E-03 0,03238933 ! positive regulation of axon extension GO:0045773 10 6 0,000 5,118E-03 0,03230319 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 5,118E-03 0,03221751 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 5,118E-03 0,03213227 ! forebrain regionalization GO:0021871 7 6 0,000 5,118E-03 0,03204749 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 5,118E-03 0,03196316 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 5,118E-03 0,03187926 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 5,118E-03 0,03179581 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 5,118E-03 0,03171279 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 5,118E-03 0,03163021 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 5,118E-03 0,03154805 ! neuron adhesion GO:0007158 9 6 0,000 5,118E-03 0,03146632 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 5,118E-03 0,03138501 ! signal peptide processing GO:0006465 8 6 0,000 5,118E-03 0,03130412 ! embryonic camera-type eye development GO:0031076 11 6 0,000 5,118E-03 0,03122365 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 5,118E-03 0,03114359 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 5,118E-03 0,03106394 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 5,118E-03 0,03098469 ! fibril organization GO:0043206 13 6 0,000 5,118E-03 0,03090585 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 5,118E-03 0,03082741 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 5,118E-03 0,03074937 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 5,118E-03 0,03067172 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 5,118E-03 0,03059446 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 5,118E-03 0,03051759 ! rhythmic behavior GO:0007622 14 6 0,000 5,118E-03 0,0304411 ! glial cell fate commitment GO:0021781 17 6 0,000 5,118E-03 0,030365 ! erythrocyte maturation GO:0043249 7 6 0,000 5,118E-03 0,03028928 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 5,118E-03 0,03021393 ! protein amino acid dealkylation GO:0008214 12 6 0,000 5,118E-03 0,03013896 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 5,118E-03 0,03006436 ! regulation of odontogenesis GO:0042481 8 6 0,000 5,118E-03 0,02999012 ! mechanosensory behavior GO:0007638 8 6 0,000 5,118E-03 0,02991626 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 5,118E-03 0,02984275 ! negative regulation of endocytosis GO:0045806 8 6 0,000 5,118E-03 0,02976961 ! response to interferon-gamma GO:0034341 12 6 0,000 5,118E-03 0,02969682 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 5,118E-03 0,02962439 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 5,118E-03 0,02955231 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 5,118E-03 0,02948058 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 5,118E-03 0,0294092 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 5,118E-03 0,02933816 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 5,118E-03 0,02926747 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 5,118E-03 0,02919712 ! cGMP-mediated signaling GO:0019934 11 6 0,000 5,118E-03 0,0291271 ! activation of MAPKKK activity GO:0000185 11 6 0,000 5,118E-03 0,02905742 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 5,118E-03 0,02898807 ! protein lipoylation GO:0009249 10 6 0,000 5,118E-03 0,02891905 ! pigment granule organization GO:0048753 11 6 0,000 5,118E-03 0,02885036 ! drug transport GO:0015893 6 6 0,000 5,118E-03 0,02878199 ! transepithelial chloride transport GO:0030321 10 6 0,000 5,118E-03 0,02871395 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 5,118E-03 0,02864623 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 5,118E-03 0,02857882 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 5,118E-03 0,02851174 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 5,118E-03 0,02844496 ! glutamate catabolic process GO:0006538 11 6 0,000 5,118E-03 0,0283785 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 5,118E-03 0,02831235 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 5,118E-03 0,02824651 ! adenohypophysis development GO:0021984 10 6 0,000 5,118E-03 0,02818097 ! response to pH GO:0009268 10 6 0,000 5,118E-03 0,02811574 ! hyperosmotic response GO:0006972 9 6 0,000 5,118E-03 0,02805081 ! microtubule nucleation GO:0007020 10 6 0,000 5,118E-03 0,02798617 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 5,118E-03 0,02792184 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 5,118E-03 0,0278578 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 5,118E-03 0,02779405 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 5,118E-03 0,02773059 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 5,118E-03 0,02766743 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 5,118E-03 0,02760455 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 5,118E-03 0,02754195 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 5,118E-03 0,02747964 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 5,118E-03 0,02741761 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 5,118E-03 0,02735586 ! purine salvage GO:0043101 9 6 0,000 5,118E-03 0,02729438 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 5,118E-03 0,02723318 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 5,118E-03 0,02717226 ! nucleoside transport GO:0015858 7 6 0,000 5,118E-03 0,02711161 ! organic alcohol transport GO:0015850 9 6 0,000 5,118E-03 0,02705122 ! T cell mediated immunity GO:0002456 12 6 0,000 5,118E-03 0,02699111 ! folic acid transport GO:0015884 11 6 0,000 5,118E-03 0,02693126 ! male sex determination GO:0030238 11 6 0,000 5,118E-03 0,02687168 ! carnitine transport GO:0015879 8 6 0,000 5,118E-03 0,02681236 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 5,118E-03 0,0267533 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,118E-03 0,02669451 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 5,118E-03 0,02663596 ! positive regulation of exocytosis GO:0045921 9 6 0,000 5,118E-03 0,02657768 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 5,118E-03 0,02651965 ! parturition GO:0007567 13 6 0,000 5,118E-03 0,02646187 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 5,118E-03 0,02640435 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 5,118E-03 0,02634707 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 5,118E-03 0,02629004 ! regulation of centrosome cycle GO:0046605 8 6 0,000 5,118E-03 0,02623326 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 5,118E-03 0,02617672 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 5,118E-03 0,02612043 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 5,118E-03 0,02606438 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 5,118E-03 0,02600857 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 5,118E-03 0,02595299 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 5,118E-03 0,02589765 ! neural nucleus development GO:0048857 12 6 0,000 5,118E-03 0,02584255 ! forebrain morphogenesis GO:0048853 14 6 0,000 5,118E-03 0,02578769 ! hyaluronan metabolic process GO:0030212 7 6 0,000 5,118E-03 0,02573305 ! purine base biosynthetic process GO:0009113 14 6 0,000 5,118E-03 0,02567865 ! interaction with symbiont GO:0051702 9 6 0,000 5,118E-03 0,02562447 ! regulation of dendrite development GO:0050773 13 6 0,000 5,118E-03 0,02557053 ! anterograde axon cargo transport GO:0008089 9 6 0,000 5,118E-03 0,02551681 ! positive regulation of organ growth GO:0046622 7 6 0,000 5,118E-03 0,02546331 ! eating behavior GO:0042755 6 6 0,000 5,118E-03 0,02541004 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 5,118E-03 0,02535699 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 5,118E-03 0,02530417 ! response to copper ion GO:0046688 9 6 0,000 5,118E-03 0,02525156 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 5,118E-03 0,02519917 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 5,118E-03 0,025147 ! establishment of melanosome localization GO:0032401 9 6 0,000 5,118E-03 0,02509504 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,118E-03 0,0250433 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 5,118E-03 0,02499177 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 5,118E-03 0,02494045 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,118E-03 0,02488934 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,118E-03 0,02483845 ! hair follicle maturation GO:0048820 8 6 0,000 5,118E-03 0,02478775 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 5,118E-03 0,02473727 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 5,118E-03 0,02468699 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 5,118E-03 0,02463692 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 5,118E-03 0,02458704 ! rhombomere development GO:0021546 6 6 0,000 5,118E-03 0,02453737 ! G2 phase GO:0051319 15 6 0,000 5,118E-03 0,0244879 GO:0000085|G2 phase of mitotic cell cycle, ! regulation of mast cell activation GO:0033003 7 6 0,000 5,118E-03 0,02443863 ! muscle cell proliferation GO:0033002 9 6 0,000 5,118E-03 0,02438956 ! membrane to membrane docking GO:0022614 12 6 0,000 5,118E-03 0,02434068 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 5,118E-03 0,024292 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 5,118E-03 0,02424351 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 5,118E-03 0,02419522 ! receptor internalization GO:0031623 9 6 0,000 5,118E-03 0,02414712 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 5,118E-03 0,02409921 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 5,118E-03 0,02405149 ! coenzyme A metabolic process GO:0015936 9 6 0,000 5,118E-03 0,02400395 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 5,118E-03 0,02395661 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 5,118E-03 0,02390945 ! peptidyl-histidine modification GO:0018202 10 6 0,000 5,118E-03 0,02386248 ! axonal fasciculation GO:0007413 10 6 0,000 5,118E-03 0,02381569 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 5,118E-03 0,02376908 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 5,118E-03 0,02372266 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 5,118E-03 0,02367641 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 5,118E-03 0,02363035 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 5,118E-03 0,02358447 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 5,118E-03 0,02353876 ! progesterone metabolic process GO:0042448 8 6 0,000 5,118E-03 0,02349323 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 5,118E-03 0,02344788 ! glycolipid catabolic process GO:0019377 14 6 0,000 5,118E-03 0,0234027 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 5,118E-03 0,02335769 ! negative regulation of axon extension GO:0030517 13 6 0,000 5,118E-03 0,02331286 ! removal of superoxide radicals GO:0019430 10 6 0,000 5,118E-03 0,0232682 ! triglyceride catabolic process GO:0019433 8 6 0,000 5,118E-03 0,02322371 ! protein modification by small protein removal GO:0070646 10 6 0,000 5,118E-03 0,02317939 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 5,118E-03 0,02313524 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 5,118E-03 0,02309125 ! glial cell migration GO:0008347 11 6 0,000 5,118E-03 0,02304744 ! blastocyst growth GO:0001832 17 6 0,000 5,118E-03 0,02300379 ! pigment granule transport GO:0051904 12 6 0,000 5,118E-03 0,0229603 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 5,118E-03 0,02291698 ! cerebellar cortex formation GO:0021697 9 6 0,000 5,118E-03 0,02287382 ! catecholamine transport GO:0051937 7 6 0,000 5,118E-03 0,02283083 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 5,118E-03 0,02278799 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 5,118E-03 0,02274532 ! organ or tissue specific immune response GO:0002251 7 6 0,000 5,118E-03 0,0227028 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 5,118E-03 0,02266045 ! spindle assembly GO:0051225 6 6 0,000 5,118E-03 0,02261825 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 5,118E-03 0,02257621 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 5,118E-03 0,02253432 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 5,118E-03 0,02249259 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 5,118E-03 0,02245102 ! NAD biosynthetic process GO:0009435 9 6 0,000 5,118E-03 0,02240959 ! positive regulation of coagulation GO:0050820 11 6 0,000 5,118E-03 0,02236832 ! cellular anion homeostasis GO:0030002 9 6 0,000 5,118E-03 0,02232721 GO:0055081|anion homeostasis, ! behavioral response to cocaine GO:0048148 13 7 0,000 5,969E-03 0,02599016 ! autophagic vacuole formation GO:0000045 12 7 0,000 5,969E-03 0,02594256 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 5,969E-03 0,02589513 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 5,969E-03 0,02584788 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 5,969E-03 0,02580079 ! prostate gland development GO:0030850 11 7 0,000 5,969E-03 0,02575388 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 5,969E-03 0,02570714 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 5,969E-03 0,02566057 ! synaptonemal complex assembly GO:0007130 11 7 0,000 5,969E-03 0,02561417 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 5,969E-03 0,02556793 ! male meiosis GO:0007140 10 7 0,000 5,969E-03 0,02552187 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 5,969E-03 0,02547596 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 5,969E-03 0,02543023 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 5,969E-03 0,02538465 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 5,969E-03 0,02533924 ! oligopeptide transport GO:0006857 11 7 0,000 5,969E-03 0,02529399 ! protein amino acid sulfation GO:0006477 9 7 0,000 5,969E-03 0,02524891 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 5,969E-03 0,02520398 ! establishment of tissue polarity GO:0007164 10 7 0,000 5,969E-03 0,02515921 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 5,969E-03 0,0251146 ! RNA methylation GO:0001510 11 7 0,000 5,969E-03 0,02507015 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 5,969E-03 0,02502586 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 5,969E-03 0,02498172 ! pericardium development GO:0060039 9 7 0,000 5,969E-03 0,02493774 ! macrophage chemotaxis GO:0048246 10 7 0,000 5,969E-03 0,02489391 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 5,969E-03 0,02485024 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 5,969E-03 0,02480672 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 5,969E-03 0,02476335 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 5,969E-03 0,02472013 ! cerebral cortex cell migration GO:0021795 11 7 0,000 5,969E-03 0,02467707 ! opsonization GO:0008228 9 7 0,000 5,969E-03 0,02463415 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 5,969E-03 0,02459138 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 5,969E-03 0,02454876 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 5,969E-03 0,02450629 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 5,969E-03 0,02446397 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 5,969E-03 0,02442179 ! chemosensory behavior GO:0007635 9 7 0,000 5,969E-03 0,02437975 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 5,969E-03 0,02433786 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 5,969E-03 0,02429612 ! leukocyte degranulation GO:0043299 11 7 0,000 5,969E-03 0,02425451 ! positive regulation of glycolysis GO:0045821 13 7 0,000 5,969E-03 0,02421305 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 5,969E-03 0,02417173 ! positive regulation of heart rate GO:0010460 11 7 0,000 5,969E-03 0,02413056 ! protein-cofactor linkage GO:0018065 13 7 0,000 5,969E-03 0,02408952 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 5,969E-03 0,02404862 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 5,969E-03 0,02400786 ! spinal cord patterning GO:0021511 9 7 0,000 5,969E-03 0,02396723 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 5,969E-03 0,02392675 ! thymic T cell selection GO:0045061 15 7 0,000 5,969E-03 0,0238864 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 5,969E-03 0,02384619 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 5,969E-03 0,02380611 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 5,969E-03 0,02376617 ! ovulation GO:0030728 8 7 0,000 5,969E-03 0,02372636 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 5,969E-03 0,02368668 ! histidine metabolic process GO:0006547 7 7 0,000 5,969E-03 0,02364714 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 5,969E-03 0,02360773 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 5,969E-03 0,02356845 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 5,969E-03 0,0235293 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 5,969E-03 0,02349027 ! thyroid hormone generation GO:0006590 11 7 0,000 5,969E-03 0,02345138 ! endosome organization GO:0007032 10 7 0,000 5,969E-03 0,02341262 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 5,969E-03 0,02337399 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 5,969E-03 0,02333548 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 5,969E-03 0,0232971 ! urea metabolic process GO:0019627 9 7 0,000 5,969E-03 0,02325884 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 5,969E-03 0,02322071 ! vesicle fusion GO:0006906 15 7 0,000 5,969E-03 0,02318271 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 5,969E-03 0,02314483 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 5,969E-03 0,02310707 ! intracellular pH reduction GO:0051452 11 7 0,000 5,969E-03 0,02306944 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 5,969E-03 0,02303193 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 5,969E-03 0,02299454 ! organ growth GO:0035265 13 7 0,000 5,969E-03 0,02295727 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 5,969E-03 0,02292012 ! Rac protein signal transduction GO:0016601 7 7 0,000 5,969E-03 0,02288309 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 5,969E-03 0,02284619 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 5,969E-03 0,0228094 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 5,969E-03 0,02277273 ! rRNA modification GO:0000154 12 7 0,000 5,969E-03 0,02273617 ! negative regulation of translational initiation GO:0045947 9 7 0,000 5,969E-03 0,02269974 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 5,969E-03 0,02266342 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! protein heterooligomerization GO:0051291 10 7 0,000 5,969E-03 0,02262721 ! response to UV-B GO:0010224 11 7 0,000 5,969E-03 0,02259113 ! astrocyte development GO:0014002 15 7 0,000 5,969E-03 0,02255515 ! intermediate filament organization GO:0045109 12 7 0,000 5,969E-03 0,02251929 ! cardiac muscle cell development GO:0055013 9 7 0,000 5,969E-03 0,02248355 ! fibrinolysis GO:0042730 9 7 0,000 5,969E-03 0,02244792 ! peptidyl-arginine modification GO:0018195 9 7 0,000 5,969E-03 0,0224124 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 5,969E-03 0,02237699 ! blastoderm segmentation GO:0007350 11 7 0,000 5,969E-03 0,0223417 ! skeletal muscle contraction GO:0003009 8 7 0,000 5,969E-03 0,02230651 ! B cell lineage commitment GO:0002326 17 7 0,000 5,969E-03 0,02227144 ! DNA topological change GO:0006265 10 7 0,000 5,969E-03 0,02223648 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 5,969E-03 0,02220162 ! melanosome localization GO:0032400 10 7 0,000 5,969E-03 0,02216688 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 5,969E-03 0,02213224 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 5,969E-03 0,02209772 ! mast cell activation GO:0045576 10 7 0,000 5,969E-03 0,0220633 ! multicellular organismal aging GO:0010259 11 7 0,000 5,969E-03 0,02202898 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 5,969E-03 0,02199478 ! gas homeostasis GO:0033483 12 7 0,000 5,969E-03 0,02196068 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 5,969E-03 0,02192668 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 5,969E-03 0,02189279 ! Schwann cell development GO:0014044 16 7 0,000 5,969E-03 0,02185901 ! dendrite morphogenesis GO:0048813 12 7 0,000 5,969E-03 0,02182532 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 5,969E-03 0,02179175 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 5,969E-03 0,02175827 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 5,969E-03 0,0217249 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 5,969E-03 0,02169163 ! neural tube patterning GO:0021532 8 7 0,000 5,969E-03 0,02165846 ! histone ubiquitination GO:0016574 10 7 0,000 5,969E-03 0,0216254 ! regulation of meiosis GO:0040020 12 7 0,000 5,969E-03 0,02159243 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 5,969E-03 0,02155957 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 5,969E-03 0,0215268 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 5,969E-03 0,02149414 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 5,969E-03 0,02146157 ! regulation of lipid transport GO:0032368 13 7 0,000 5,969E-03 0,0214291 ! regulation of cell division GO:0051302 9 7 0,000 5,969E-03 0,02139673 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 5,969E-03 0,02136446 ! neutrophil homeostasis GO:0001780 8 7 0,000 5,969E-03 0,02133228 ! regulation of macrophage activation GO:0043030 12 7 0,000 5,969E-03 0,0213002 ! negative regulation of nuclear division GO:0051784 18 7 0,000 5,969E-03 0,02126822 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 5,969E-03 0,02123634 ! diuresis GO:0030146 11 7 0,000 5,969E-03 0,02120454 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 5,969E-03 0,02117285 ! positive regulation of epidermis development GO:0045684 11 7 0,000 5,969E-03 0,02114125 ! thiamin metabolic process GO:0006772 8 7 0,000 5,969E-03 0,02110974 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 5,969E-03 0,02107833 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 5,969E-03 0,02104701 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 5,969E-03 0,02101578 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 5,969E-03 0,02098465 ! dopamine biosynthetic process GO:0042416 15 7 0,000 5,969E-03 0,0209536 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 5,969E-03 0,02092265 ! lymph node development GO:0048535 9 7 0,000 5,969E-03 0,02089179 ! anterior/posterior axis specification GO:0009948 11 7 0,000 5,969E-03 0,02086102 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 5,969E-03 0,02083035 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 5,969E-03 0,02079976 ! positive regulation of glucose import GO:0046326 7 7 0,000 5,969E-03 0,02076926 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 5,969E-03 0,02073885 ! ATP catabolic process GO:0006200 10 7 0,000 5,969E-03 0,02070853 ! establishment of pigment granule localization GO:0051905 13 7 0,000 5,969E-03 0,0206783 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 5,969E-03 0,02064816 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 5,969E-03 0,0206181 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 5,969E-03 0,02058813 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 5,969E-03 0,02055825 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 5,969E-03 0,02052846 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 5,969E-03 0,02049875 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 5,969E-03 0,02046913 ! muscle adaptation GO:0043500 12 7 0,000 5,969E-03 0,02043959 ! amino sugar catabolic process GO:0046348 9 7 0,000 5,969E-03 0,02041014 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 5,969E-03 0,02038077 ! retina homeostasis GO:0001895 9 7 0,000 5,969E-03 0,02035149 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 5,969E-03 0,02032229 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 5,969E-03 0,02029317 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 5,969E-03 0,02026414 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 5,969E-03 0,02023519 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 5,969E-03 0,02020633 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 6,819E-03 0,02305078 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 6,819E-03 0,02301799 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 6,819E-03 0,02298529 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 6,819E-03 0,02295269 ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 6,819E-03 0,02292018 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 6,819E-03 0,02288776 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 6,819E-03 0,02285543 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 6,819E-03 0,0228232 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 6,819E-03 0,02279105 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 6,819E-03 0,022759 ! cell proliferation in forebrain GO:0021846 10 8 0,000 6,819E-03 0,02272703 ! neutral lipid catabolic process GO:0046461 11 8 0,000 6,819E-03 0,02269516 ! N-glycan processing GO:0006491 12 8 0,000 6,819E-03 0,02266337 ! Golgi to endosome transport GO:0006895 16 8 0,000 6,819E-03 0,02263167 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 6,819E-03 0,02260007 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 6,819E-03 0,02256855 ! mRNA stabilization GO:0048255 16 8 0,000 6,819E-03 0,02253711 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 6,819E-03 0,02250577 ! neurotransmitter uptake GO:0001504 10 8 0,000 6,819E-03 0,02247451 ! lipoprotein transport GO:0042953 14 8 0,000 6,819E-03 0,02244334 ! membrane hyperpolarization GO:0060081 11 8 0,000 6,819E-03 0,02241225 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 6,819E-03 0,02238125 ! keratinocyte proliferation GO:0043616 15 8 0,000 6,819E-03 0,02235034 ! middle ear morphogenesis GO:0042474 9 8 0,000 6,819E-03 0,02231951 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 6,819E-03 0,02228877 ! bile acid and bile salt transport GO:0015721 12 8 0,000 6,819E-03 0,02225811 ! ganglioside metabolic process GO:0001573 16 8 0,000 6,819E-03 0,02222754 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 6,819E-03 0,02219705 ! reflex GO:0060004 16 8 0,000 6,819E-03 0,02216664 ! positive regulation of isotype switching GO:0045830 16 8 0,000 6,819E-03 0,02213632 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 6,819E-03 0,02210608 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 6,819E-03 0,02207592 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 6,819E-03 0,02204584 ! glycerolipid catabolic process GO:0046503 11 8 0,000 6,819E-03 0,02201585 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 6,819E-03 0,02198593 ! hemoglobin metabolic process GO:0020027 12 8 0,000 6,819E-03 0,0219561 ! ceramide biosynthetic process GO:0046513 9 8 0,000 6,819E-03 0,02192635 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 6,819E-03 0,02189668 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 6,819E-03 0,02186709 ! adrenal gland development GO:0030325 18 8 0,000 6,819E-03 0,02183758 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 6,819E-03 0,02180815 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 6,819E-03 0,0217788 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 6,819E-03 0,02174953 ! proline metabolic process GO:0006560 9 8 0,000 6,819E-03 0,02172033 ! polyamine biosynthetic process GO:0006596 9 8 0,000 6,819E-03 0,02169122 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 6,819E-03 0,02166218 ! regulation of pigmentation during development GO:0048070 18 8 0,000 6,819E-03 0,02163322 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 6,819E-03 0,02160434 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 6,819E-03 0,02157553 ! regulation of type I interferon production GO:0032479 8 8 0,000 6,819E-03 0,0215468 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 6,819E-03 0,02151815 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 6,819E-03 0,02148957 ! galactose metabolic process GO:0006012 14 8 0,000 6,819E-03 0,02146107 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 6,819E-03 0,02143265 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,819E-03 0,0214043 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 6,819E-03 0,02137602 ! ruffle organization GO:0031529 12 8 0,000 6,819E-03 0,02134782 ! osteoblast development GO:0002076 14 8 0,000 6,819E-03 0,02131969 ! macroautophagy GO:0016236 14 8 0,000 6,819E-03 0,02129164 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 6,819E-03 0,02126366 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 6,819E-03 0,02123576 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 6,819E-03 0,02120793 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 6,819E-03 0,02118017 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 6,819E-03 0,02115248 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 6,819E-03 0,02112487 ! protein retention in ER lumen GO:0006621 16 8 0,000 6,819E-03 0,02109732 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 6,819E-03 0,02106985 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 6,819E-03 0,02104245 ! regulation of circadian rhythm GO:0042752 13 8 0,000 6,819E-03 0,02101513 ! pigment granule localization GO:0051875 14 8 0,000 6,819E-03 0,02098787 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 6,819E-03 0,02096068 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 6,819E-03 0,02093357 ! response to tropane GO:0014073 14 8 0,000 6,819E-03 0,02090652 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 6,819E-03 0,02087954 ! embryonic axis specification GO:0000578 12 8 0,000 6,819E-03 0,02085264 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 6,819E-03 0,0208258 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 6,819E-03 0,02079903 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 6,819E-03 0,02077233 ! snRNA metabolic process GO:0016073 10 8 0,000 6,819E-03 0,0207457 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 6,819E-03 0,02071914 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 6,819E-03 0,02069264 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 6,819E-03 0,02066622 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 6,819E-03 0,02063986 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 6,819E-03 0,02061356 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 6,819E-03 0,02058734 ! establishment of nucleus localization GO:0040023 14 8 0,000 6,819E-03 0,02056118 ! icosanoid secretion GO:0032309 12 8 0,000 6,819E-03 0,02053509 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 6,819E-03 0,02050906 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 6,819E-03 0,0204831 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 6,819E-03 0,0204572 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 6,819E-03 0,02043137 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 6,819E-03 0,02040561 ! S phase GO:0051320 8 8 0,000 6,819E-03 0,02037991 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 6,819E-03 0,02035427 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 6,819E-03 0,0203287 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 6,819E-03 0,0203032 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 6,819E-03 0,02027775 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 6,819E-03 0,02025237 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 6,819E-03 0,02022706 ! melanin biosynthetic process GO:0042438 11 8 0,000 6,819E-03 0,02020181 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 6,819E-03 0,02017662 ! regulation of synaptogenesis GO:0051963 12 8 0,000 6,819E-03 0,02015149 ! hormone catabolic process GO:0042447 13 8 0,000 6,819E-03 0,02012643 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 6,819E-03 0,02010142 ! quaternary ammonium group transport GO:0015697 10 8 0,000 6,819E-03 0,02007649 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 6,819E-03 0,02005161 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 6,819E-03 0,02002679 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 6,819E-03 0,02000204 ! regulation of telomere maintenance GO:0032204 10 8 0,000 6,819E-03 0,01997734 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 6,819E-03 0,01995271 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 6,819E-03 0,01992814 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 6,819E-03 0,01990362 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 6,819E-03 0,01987917 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 6,819E-03 0,01985478 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 6,819E-03 0,01983045 ! negative regulation of B cell activation GO:0050869 17 8 0,000 6,819E-03 0,01980618 ! behavioral response to nicotine GO:0035095 13 8 0,000 6,819E-03 0,01978196 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 6,819E-03 0,01975781 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 6,819E-03 0,01973372 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 6,819E-03 0,01970968 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 6,819E-03 0,0196857 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 6,819E-03 0,01966178 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 7,668E-03 0,02208378 ! regulation of developmental growth GO:0048638 14 9 0,000 7,668E-03 0,02205701 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 7,668E-03 0,02203031 ! telencephalon cell migration GO:0022029 16 9 0,000 7,668E-03 0,02200367 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 7,668E-03 0,0219771 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 7,668E-03 0,02195059 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 7,668E-03 0,02192414 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 7,668E-03 0,02189776 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 7,668E-03 0,02187144 ! cell volume homeostasis GO:0006884 14 9 0,000 7,668E-03 0,02184518 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 7,668E-03 0,02181899 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 7,668E-03 0,02179286 ! UTP metabolic process GO:0046051 10 9 0,000 7,668E-03 0,02176679 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 7,668E-03 0,02174078 GO:0046457|prostanoid biosynthetic process, ! smoothened signaling pathway GO:0007224 10 9 0,000 7,668E-03 0,02171484 ! protein complex disassembly GO:0043241 17 9 0,000 7,668E-03 0,02168896 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 7,668E-03 0,02166314 ! estrogen metabolic process GO:0008210 16 9 0,000 7,668E-03 0,02163738 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 7,668E-03 0,02161168 ! photoreceptor cell development GO:0042461 17 9 0,000 7,668E-03 0,02158604 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 7,668E-03 0,02156047 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 7,668E-03 0,02153495 ! microtubule bundle formation GO:0001578 14 9 0,000 7,668E-03 0,0215095 ! T-helper 1 type immune response GO:0042088 13 9 0,000 7,668E-03 0,0214841 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 7,668E-03 0,02145877 ! lung alveolus development GO:0048286 18 9 0,000 7,668E-03 0,02143349 ! ciliary or flagellar motility GO:0001539 10 9 0,000 7,668E-03 0,02140828 ! pseudouridine synthesis GO:0001522 10 9 0,000 7,668E-03 0,02138312 ! endothelial cell differentiation GO:0045446 17 9 0,000 7,668E-03 0,02135802 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 7,668E-03 0,02133298 ! endoderm development GO:0007492 12 9 0,000 7,668E-03 0,021308 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 7,668E-03 0,02128308 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 7,668E-03 0,02125822 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 7,668E-03 0,02123341 ! astrocyte differentiation GO:0048708 17 9 0,000 7,668E-03 0,02120867 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 7,668E-03 0,02118398 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 7,668E-03 0,02115934 ! phosphagen metabolic process GO:0006599 12 9 0,000 7,668E-03 0,02113477 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 7,668E-03 0,02111025 ! reverse cholesterol transport GO:0043691 17 9 0,000 7,668E-03 0,02108579 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 7,668E-03 0,02106138 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 7,668E-03 0,02103703 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 7,668E-03 0,02101274 ! macrophage activation GO:0042116 14 9 0,000 7,668E-03 0,02098851 ! multicellular organism growth GO:0035264 16 9 0,000 7,668E-03 0,02096433 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 7,668E-03 0,0209402 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 7,668E-03 0,02091613 ! neuron apoptosis GO:0051402 12 9 0,000 7,668E-03 0,02089212 ! lens development in camera-type eye GO:0002088 11 9 0,000 7,668E-03 0,02086816 ! positive regulation of vasodilation GO:0045909 14 9 0,000 7,668E-03 0,02084426 ! retinoic acid metabolic process GO:0042573 11 9 0,000 7,668E-03 0,02082041 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 7,668E-03 0,02079661 ! positive regulation of translational initiation GO:0045948 10 9 0,000 7,668E-03 0,02077287 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 7,668E-03 0,02074918 ! Schwann cell differentiation GO:0014037 20 9 0,000 7,668E-03 0,02072555 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 7,668E-03 0,02070197 ! regulation of gliogenesis GO:0014013 21 9 0,000 7,668E-03 0,02067845 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 7,668E-03 0,02065498 ! oligodendrocyte development GO:0014003 13 9 0,000 7,668E-03 0,02063156 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 7,668E-03 0,02060819 ! segment specification GO:0007379 11 9 0,000 7,668E-03 0,02058488 ! cellular extravasation GO:0045123 12 9 0,000 7,668E-03 0,02056162 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 7,668E-03 0,02053841 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 7,668E-03 0,02051526 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 7,668E-03 0,02049216 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 7,668E-03 0,02046911 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 7,668E-03 0,02044611 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 7,668E-03 0,02042316 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 7,668E-03 0,02040026 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 7,668E-03 0,02037742 ! response to amine stimulus GO:0014075 13 9 0,000 7,668E-03 0,02035463 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 7,668E-03 0,02033188 ! erythrocyte development GO:0048821 13 9 0,000 7,668E-03 0,02030919 ! renal water homeostasis GO:0003091 13 9 0,000 7,668E-03 0,02028655 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 7,668E-03 0,02026396 ! nucleosome disassembly GO:0006337 13 9 0,000 7,668E-03 0,02024142 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 7,668E-03 0,02021893 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 7,668E-03 0,02019649 ! induction of an organ GO:0001759 13 9 0,000 7,668E-03 0,0201741 ! leukocyte activation during immune response GO:0002366 15 9 0,000 7,668E-03 0,02015176 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 7,668E-03 0,02012946 ! cerebellum morphogenesis GO:0021587 13 9 0,000 7,668E-03 0,02010722 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 7,668E-03 0,02008503 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 7,668E-03 0,02006288 ! sterol catabolic process GO:0016127 11 9 0,000 7,668E-03 0,02004079 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 7,668E-03 0,02001874 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 7,668E-03 0,01999674 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 7,668E-03 0,01997479 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 7,668E-03 0,01995289 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 7,668E-03 0,01993104 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 7,668E-03 0,01990923 ! prophase GO:0051324 12 9 0,000 7,668E-03 0,01988747 ! neuroblast proliferation GO:0007405 19 9 0,000 7,668E-03 0,01986576 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 7,668E-03 0,01984409 ! peptidyl-threonine modification GO:0018210 22 9 0,000 7,668E-03 0,01982248 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 7,668E-03 0,01980091 ! ubiquinone metabolic process GO:0006743 11 9 0,000 7,668E-03 0,01977939 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 7,668E-03 0,01975791 ! acid secretion GO:0046717 14 9 0,000 7,668E-03 0,01973648 ! purine base metabolic process GO:0006144 18 9 0,000 7,668E-03 0,0197151 ! detection of calcium ion GO:0005513 13 9 0,000 7,668E-03 0,01969376 ! myeloid cell homeostasis GO:0002262 10 9 0,000 7,668E-03 0,01967247 ! regulation of fibrinolysis GO:0051917 14 9 0,000 7,668E-03 0,01965123 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 7,668E-03 0,01963003 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 7,668E-03 0,01960887 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 7,668E-03 0,01958777 ! regulation of muscle adaptation GO:0043502 12 9 0,000 7,668E-03 0,0195667 ! regulation of amino acid transport GO:0051955 11 9 0,000 7,668E-03 0,01954569 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 7,668E-03 0,01952472 ! prepulse inhibition GO:0060134 14 9 0,000 7,668E-03 0,01950379 ! sequestering of metal ion GO:0051238 12 9 0,000 7,668E-03 0,01948291 ! lamellipodium assembly GO:0030032 12 9 0,000 7,668E-03 0,01946207 ! regulation of embryonic development GO:0045995 17 9 0,000 7,668E-03 0,01944128 ! mitochondrion localization GO:0051646 15 9 0,000 7,668E-03 0,01942053 ! localization within membrane GO:0051668 15 9 0,000 7,668E-03 0,01939982 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 8,517E-03 0,02152375 ! axon extension GO:0048675 13 10 0,000 8,517E-03 0,02150085 ! neuron fate specification GO:0048665 12 10 0,000 8,517E-03 0,021478 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 8,517E-03 0,0214552 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 8,517E-03 0,02143245 ! associative learning GO:0008306 19 10 0,000 8,517E-03 0,02140975 ! positive regulation of B cell proliferation GO:0030890 14 10 0,000 8,517E-03 0,02138709 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 8,517E-03 0,02136448 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 8,517E-03 0,02134192 ! CTP metabolic process GO:0046036 11 10 0,000 8,517E-03 0,02131941 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 8,517E-03 0,02129694 ! GTP metabolic process GO:0046039 11 10 0,000 8,517E-03 0,02127453 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 8,517E-03 0,02125216 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 8,517E-03 0,02122983 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 8,517E-03 0,02120756 ! social behavior GO:0035176 15 10 0,000 8,517E-03 0,02118533 ! sulfate transport GO:0008272 12 10 0,000 8,517E-03 0,02116314 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 8,517E-03 0,02114101 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 8,517E-03 0,02111891 ! artery development GO:0060840 20 10 0,000 8,517E-03 0,02109687 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 8,517E-03 0,02107487 ! response to pain GO:0048265 20 10 0,000 8,517E-03 0,02105292 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 8,517E-03 0,02103101 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 8,517E-03 0,02100915 ! phospholipid efflux GO:0033700 17 10 0,000 8,517E-03 0,02098733 ! hippocampus development GO:0021766 19 10 0,000 8,517E-03 0,02096556 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 8,517E-03 0,02094384 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 8,517E-03 0,02092215 ! blood vessel remodeling GO:0001974 23 10 0,000 8,517E-03 0,02090052 ! positive regulation of heart contraction GO:0045823 16 10 0,000 8,517E-03 0,02087893 ! pathogenesis GO:0009405 13 10 0,000 8,517E-03 0,02085738 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 8,517E-03 0,02083588 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 8,517E-03 0,02081442 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 8,517E-03 0,020793 ! protein targeting to ER GO:0045047 21 10 0,000 8,517E-03 0,02077163 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 8,517E-03 0,02075031 ! arginine catabolic process GO:0006527 12 10 0,000 8,517E-03 0,02072903 ! melanocyte differentiation GO:0030318 16 10 0,000 8,517E-03 0,02070779 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 8,517E-03 0,02068659 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 8,517E-03 0,02066544 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 8,517E-03 0,02064433 ! B cell proliferation GO:0042100 16 10 0,000 8,517E-03 0,02062327 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 8,517E-03 0,02060224 ! mannose metabolic process GO:0006013 11 10 0,000 8,517E-03 0,02058126 ! regulation of sodium ion transport GO:0002028 15 10 0,000 8,517E-03 0,02056033 ! forebrain cell migration GO:0021885 17 10 0,000 8,517E-03 0,02053943 ! lipid digestion GO:0044241 15 10 0,000 8,517E-03 0,02051858 ! substrate-bound cell migration GO:0006929 11 10 0,000 8,517E-03 0,02049777 ! phagocytosis, engulfment GO:0006911 20 10 0,000 8,517E-03 0,020477 ! receptor clustering GO:0043113 18 10 0,000 8,517E-03 0,02045628 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 8,517E-03 0,02043559 ! UV protection GO:0009650 14 10 0,000 8,517E-03 0,02041495 ! entry into host cell GO:0030260 21 10 0,000 8,517E-03 0,02039435 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 8,517E-03 0,02037379 ! behavioral fear response GO:0001662 19 10 0,000 8,517E-03 0,02035327 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 8,517E-03 0,0203328 ! negative regulation of ossification GO:0030279 21 10 0,000 8,517E-03 0,02031236 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 8,517E-03 0,02029197 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 8,517E-03 0,02027162 ! response to dsRNA GO:0043331 19 10 0,000 8,517E-03 0,0202513 ! DNA ligation GO:0006266 16 10 0,000 8,517E-03 0,02023103 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 8,517E-03 0,0202108 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 8,517E-03 0,02019061 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 8,517E-03 0,02017046 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 8,517E-03 0,02015035 ! postreplication repair GO:0006301 16 10 0,000 8,517E-03 0,02013028 ! fucose catabolic process GO:0019317 17 10 0,000 8,517E-03 0,02011025 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 8,517E-03 0,02009026 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 8,517E-03 0,02007031 ! hindbrain morphogenesis GO:0021575 16 10 0,000 8,517E-03 0,0200504 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 8,517E-03 0,02003053 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 8,517E-03 0,02001069 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 8,517E-03 0,0199909 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 8,517E-03 0,01997115 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 8,517E-03 0,01995143 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 8,517E-03 0,01993176 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 8,517E-03 0,01991212 ! methionine biosynthetic process GO:0009086 13 10 0,000 8,517E-03 0,01989252 ! oocyte differentiation GO:0009994 14 10 0,000 8,517E-03 0,01987296 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 8,517E-03 0,01985344 ! spleen development GO:0048536 17 10 0,000 8,517E-03 0,01983396 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 8,517E-03 0,01981451 ! regulation of RNA splicing GO:0043484 15 10 0,000 8,517E-03 0,0197951 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 8,517E-03 0,01977573 ! blastocyst formation GO:0001825 14 10 0,000 8,517E-03 0,0197564 ! embryonic gut development GO:0048566 13 10 0,000 8,517E-03 0,01973711 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 8,517E-03 0,01971785 ! cerebellar cortex development GO:0021695 14 10 0,000 8,517E-03 0,01969864 ! activation of innate immune response GO:0002218 10 10 0,000 8,517E-03 0,01967946 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 8,517E-03 0,01966031 ! insulin secretion GO:0030073 18 10 0,000 8,517E-03 0,01964121 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 8,517E-03 0,01962214 ! response to nicotine GO:0035094 18 10 0,000 8,517E-03 0,0196031 ! establishment of cell polarity GO:0030010 12 10 0,000 8,517E-03 0,01958411 ! nucleus localization GO:0051647 16 10 0,000 8,517E-03 0,01956515 ! regulation of synapse organization GO:0050807 14 10 0,000 8,517E-03 0,01954623 ! negative regulation of muscle development GO:0048635 14 11 0,000 9,365E-03 0,02147145 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 9,365E-03 0,02145072 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 9,365E-03 0,02143003 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 9,365E-03 0,02140939 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 9,365E-03 0,02138878 ! virus-host interaction GO:0019048 20 11 0,000 9,365E-03 0,02136822 ! thyroid gland development GO:0030878 20 11 0,000 9,365E-03 0,02134769 ! pentose-phosphate shunt GO:0006098 14 11 0,000 9,365E-03 0,0213272 GO:0006740|NADPH regeneration, ! non-recombinational repair GO:0000726 19 11 0,000 9,365E-03 0,02130676 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 9,365E-03 0,02128635 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 9,365E-03 0,02126598 ! Golgi vesicle budding GO:0048194 18 11 0,000 9,365E-03 0,02124565 ! elastic fiber assembly GO:0048251 17 11 0,000 9,365E-03 0,02122535 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 9,365E-03 0,0212051 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 9,365E-03 0,02118489 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 9,365E-03 0,02116471 ! regulation of cell projection assembly GO:0060491 22 11 0,000 9,365E-03 0,02114457 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 9,365E-03 0,02112447 ! bone resorption GO:0045453 16 11 0,000 9,365E-03 0,02110441 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 9,365E-03 0,02108439 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 9,365E-03 0,0210644 ! ventral spinal cord development GO:0021517 15 11 0,000 9,365E-03 0,02104446 ! regulated secretory pathway GO:0045055 15 11 0,000 9,365E-03 0,02102455 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 9,365E-03 0,02100467 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 9,365E-03 0,02098484 ! syncytium formation GO:0006949 15 11 0,000 9,365E-03 0,02096504 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 9,365E-03 0,02094528 ! glucan biosynthetic process GO:0009250 14 11 0,000 9,365E-03 0,02092556 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 9,365E-03 0,02090588 ! Golgi organization GO:0007030 19 11 0,000 9,365E-03 0,02088623 ! response to X-ray GO:0010165 19 11 0,000 9,365E-03 0,02086662 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 9,365E-03 0,02084704 ! adult heart development GO:0007512 12 11 0,000 9,365E-03 0,0208275 ! chondrocyte differentiation GO:0002062 17 11 0,000 9,365E-03 0,020808 ! epithelial cell development GO:0002064 16 11 0,000 9,365E-03 0,02078854 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 9,365E-03 0,02076911 ! temperature homeostasis GO:0001659 16 11 0,000 9,365E-03 0,02074972 ! L-glutamate transport GO:0015813 15 11 0,000 9,365E-03 0,02073036 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 9,365E-03 0,02071104 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 9,365E-03 0,02069176 ! motor axon guidance GO:0008045 17 11 0,000 9,365E-03 0,02067251 ! copper ion homeostasis GO:0055070 15 11 0,000 9,365E-03 0,0206533 ! protein targeting to peroxisome GO:0006625 21 11 0,000 9,365E-03 0,02063412 ! regulation of bone resorption GO:0045124 27 11 0,000 9,365E-03 0,02061498 ! stem cell development GO:0048864 30 11 0,000 9,365E-03 0,02059587 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 9,365E-03 0,0205768 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 9,365E-03 0,02055777 ! regulation of phagocytosis GO:0050764 16 11 0,000 9,365E-03 0,02053877 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 9,365E-03 0,0205198 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 9,365E-03 0,02050087 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 9,365E-03 0,02048198 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 9,365E-03 0,02046312 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 9,365E-03 0,02044429 ! regulation of B cell differentiation GO:0045577 23 11 0,000 9,365E-03 0,0204255 ! cranial nerve development GO:0021545 14 11 0,000 9,365E-03 0,02040675 ! nitric oxide metabolic process GO:0046209 15 11 0,000 9,365E-03 0,02038802 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 9,365E-03 0,02036934 ! salivary gland development GO:0007431 24 11 0,000 9,365E-03 0,02035068 ! negative regulation of neurological system process GO:0031645 20 11 0,000 9,365E-03 0,02033206 ! regulation of leukocyte migration GO:0002685 25 11 0,000 9,365E-03 0,02031348 ! musculoskeletal movement GO:0050881 16 11 0,000 9,365E-03 0,02029493 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 9,365E-03 0,02027641 ! protein-chromophore linkage GO:0018298 13 11 0,000 9,365E-03 0,02025793 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 9,365E-03 0,02023948 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 20 11 0,000 9,365E-03 0,02022106 ! digestive tract morphogenesis GO:0048546 16 11 0,000 9,365E-03 0,02020268 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 9,365E-03 0,02018433 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 9,365E-03 0,02016601 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 9,365E-03 0,02014773 ! negative regulation of glucose import GO:0046325 14 11 0,000 9,365E-03 0,02012948 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 9,365E-03 0,02011126 ! regulation of organic acid transport GO:0032890 17 11 0,000 9,365E-03 0,02009308 ! cardiac cell differentiation GO:0035051 18 11 0,000 9,365E-03 0,02007493 ! defense response to fungus GO:0050832 13 11 0,000 9,365E-03 0,02005681 ! lysogeny GO:0030069 20 11 0,000 9,365E-03 0,02003872 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 9,365E-03 0,02002067 ! acrosome reaction GO:0007340 14 11 0,000 9,365E-03 0,02000265 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 9,365E-03 0,01998466 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 9,365E-03 0,01996671 ! rRNA transcription GO:0009303 19 12 0,000 0,01021217 0,02175356 ! reproductive cellular process GO:0048610 15 12 0,000 0,01021217 0,02173405 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01021217 0,02171458 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01021217 0,02169514 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01021217 0,02167573 ! phosphate transport GO:0006817 15 12 0,000 0,01021217 0,02165636 ! peroxisomal transport GO:0043574 22 12 0,000 0,01021217 0,02163703 ! mating GO:0007618 16 12 0,000 0,01021217 0,02161773 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01021217 0,02159846 ! heart looping GO:0001947 15 12 0,000 0,01021217 0,02157923 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01021217 0,02156003 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01021217 0,02154086 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01021217 0,02152173 ! T cell selection GO:0045058 25 12 0,000 0,01021217 0,02150264 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01021217 0,02148357 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,01021217 0,02146454 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01021217 0,02144555 ! plasma membrane organization GO:0007009 19 12 0,000 0,01021217 0,02142659 ! focal adhesion formation GO:0048041 28 12 0,000 0,01021217 0,02140766 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01021217 0,02138877 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01021217 0,0213699 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01021217 0,02135108 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01021217 0,02133228 ! monoamine transport GO:0015844 14 12 0,000 0,01021217 0,02131352 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01021217 0,02129479 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01021217 0,02127609 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01021217 0,02125743 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01021217 0,0212388 ! regulation of organ growth GO:0046620 14 12 0,000 0,01021217 0,0212202 ! vasoconstriction GO:0042310 18 12 0,000 0,01021217 0,02120164 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01021217 0,0211831 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01021217 0,0211646 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01021217 0,02114614 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01021217 0,0211277 ! histone deacetylation GO:0016575 14 12 0,000 0,01021217 0,0211093 ! histone acetylation GO:0016573 27 12 0,000 0,01021217 0,02109092 ! DNA methylation GO:0006306 19 12 0,000 0,01021217 0,02107258 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,01021217 0,02105428 ! protein sumoylation GO:0016925 14 12 0,000 0,01021217 0,021036 ! chromatin silencing GO:0006342 23 12 0,000 0,01021217 0,02101775 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01021217 0,02099954 ! gland morphogenesis GO:0022612 24 12 0,000 0,01021217 0,02098136 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01021217 0,02096321 ! zymogen activation GO:0031638 16 12 0,000 0,01021217 0,02094509 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01021217 0,020927 ! nucleosome positioning GO:0016584 13 12 0,000 0,01021217 0,02090895 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01021217 0,02089092 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01021217 0,02087293 ! response to gamma radiation GO:0010332 21 12 0,000 0,01021217 0,02085497 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01021217 0,02083703 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01021217 0,02081913 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01021217 0,02080126 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01021217 0,02078342 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01021217 0,02076561 ! male genitalia development GO:0030539 15 12 0,000 0,01021217 0,02074783 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01021217 0,02073009 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01021217 0,02071237 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01021217 0,02069468 ! developmental induction GO:0031128 16 12 0,000 0,01021217 0,02067702 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,01021217 0,0206594 ! response to cold GO:0009409 15 12 0,000 0,01021217 0,0206418 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01021217 0,02062423 ! respiratory burst GO:0045730 22 13 0,000 0,01105873 0,02231495 ! lactation GO:0007595 22 13 0,000 0,01105873 0,02229599 ! tRNA modification GO:0006400 15 13 0,000 0,01105873 0,02227706 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,01105873 0,02225817 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,01105873 0,0222393 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01105873 0,02222047 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,01105873 0,02220167 ! water transport GO:0006833 21 13 0,000 0,01105873 0,02218291 GO:0042044|fluid transport, ! regulation of B cell proliferation GO:0030888 24 13 0,000 0,01105873 0,02216417 ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,01105873 0,02214547 ! copper ion transport GO:0006825 15 13 0,000 0,01105873 0,02212679 ! filopodium assembly GO:0046847 21 13 0,000 0,01105873 0,02210815 ! lipid localization GO:0010876 25 13 0,000 0,01105873 0,02208954 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,01105873 0,02207097 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,01105873 0,02205242 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,01105873 0,0220339 ! T cell proliferation GO:0042098 24 13 0,000 0,01105873 0,02201542 ! organelle fusion GO:0048284 29 13 0,000 0,01105873 0,02199696 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01105873 0,02197854 ! endocrine pancreas development GO:0031018 19 13 0,000 0,01105873 0,02196015 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,01105873 0,02194179 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,01105873 0,02192346 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,01105873 0,02190516 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,01105873 0,02188689 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,01105873 0,02186865 ! methionine metabolic process GO:0006555 16 13 0,000 0,01105873 0,02185044 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,01105873 0,02183226 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01105873 0,02181411 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,01105873 0,02179599 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,01105873 0,02177791 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,01105873 0,02175985 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,01105873 0,02174182 ! neutral amino acid transport GO:0015804 20 13 0,000 0,01105873 0,02172382 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,01105873 0,02170585 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,01105873 0,02168792 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,01105873 0,02167001 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,01105873 0,02165213 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01105873 0,02163428 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01105873 0,02161646 ! cellular pigmentation GO:0033059 24 13 0,000 0,01105873 0,02159866 ! histone methylation GO:0016571 16 13 0,000 0,01105873 0,0215809 ! regulation of epidermis development GO:0045682 21 13 0,000 0,01105873 0,02156317 ! oxygen transport GO:0015671 20 13 0,000 0,01105873 0,02154547 ! regulation of axon extension GO:0030516 26 13 0,000 0,01105873 0,02152779 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,01105873 0,02151015 ! detection of bacterium GO:0016045 13 13 0,000 0,01105873 0,02149253 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,01105873 0,02147494 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,01105873 0,02145738 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,01105873 0,02143985 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,01105873 0,02142235 ! actin filament polymerization GO:0030041 18 13 0,000 0,01105873 0,02140488 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,01190462 0,02302336 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,01190462 0,02300462 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,01190462 0,0229859 ! neuron maturation GO:0042551 24 14 0,000 0,01190462 0,02296721 ! regulation of S phase GO:0033261 25 14 0,000 0,01190462 0,02294855 ! regulation of chemokine production GO:0032642 18 14 0,000 0,01190462 0,02292992 ! myotube differentiation GO:0014902 21 14 0,000 0,01190462 0,02291133 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,01190462 0,02289276 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,01190462 0,02287422 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,01190462 0,02285572 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,01190462 0,02283724 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,01190462 0,02281879 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,01190462 0,02280038 ! RNA polyadenylation GO:0043631 21 14 0,000 0,01190462 0,02278199 ! cartilage condensation GO:0001502 22 14 0,000 0,01190462 0,02276363 ! gene silencing by RNA GO:0031047 22 14 0,000 0,01190462 0,0227453 ! response to cAMP GO:0051591 20 14 0,000 0,01190462 0,02272701 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,01190462 0,02270874 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,01190462 0,0226905 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,01190462 0,02267229 ! limbic system development GO:0021761 25 14 0,000 0,01190462 0,0226541 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,01190462 0,02263595 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,01190462 0,02261783 ! palate development GO:0060021 19 14 0,000 0,01190462 0,02259973 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,01190462 0,02258167 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,01190462 0,02256363 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,01190462 0,02254562 ! response to hexose stimulus GO:0009746 22 14 0,000 0,01190462 0,02252765 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,01190462 0,0225097 ! arginine metabolic process GO:0006525 17 14 0,000 0,01190462 0,02249177 ! glycine metabolic process GO:0006544 22 14 0,000 0,01190462 0,02247388 ! pituitary gland development GO:0021983 24 14 0,000 0,01190462 0,02245602 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,01190462 0,02243818 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,01190462 0,02242037 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,01190462 0,02240259 ! cytokine metabolic process GO:0042107 18 14 0,000 0,01190462 0,02238484 ! NAD metabolic process GO:0019674 25 14 0,000 0,01190462 0,02236712 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,01190462 0,02234942 ! regulation of heart rate GO:0002027 26 14 0,000 0,01190462 0,02233175 ! exocrine system development GO:0035272 29 14 0,000 0,01190462 0,02231411 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,01190462 0,0222965 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,01190462 0,02227892 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,01190462 0,02226136 ! axon cargo transport GO:0008088 29 14 0,000 0,01190462 0,02224383 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,01190462 0,02222633 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,01190462 0,02220886 ! genitalia development GO:0048806 18 14 0,000 0,01190462 0,02219141 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,01190462 0,02217399 ! autonomic nervous system development GO:0048483 26 14 0,000 0,01190462 0,0221566 ! tissue regeneration GO:0042246 24 14 0,000 0,01190462 0,02213924 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,01190462 0,0221219 ! water homeostasis GO:0030104 23 14 0,000 0,01190462 0,02210459 ! cofactor transport GO:0051181 22 14 0,000 0,01190462 0,02208731 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,01190462 0,02207005 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,01190462 0,02205282 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01190462 0,02203562 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01190462 0,02201845 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,01190462 0,0220013 ! cell killing GO:0001906 22 14 0,000 0,01190462 0,02198418 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,01190462 0,02196708 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,01190462 0,02195001 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,01190462 0,02193297 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,01190462 0,02191596 ! microspike assembly GO:0030035 25 14 0,000 0,01190462 0,02189897 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,01190462 0,021882 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,01274983 0,02341745 ! superoxide anion generation GO:0042554 19 15 0,000 0,01274983 0,02339934 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,01274983 0,02338125 ! skin development GO:0043588 28 15 0,000 0,01274983 0,0233632 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,01274983 0,02334517 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,01274983 0,02332717 ! inositol metabolic process GO:0006020 21 15 0,000 0,01274983 0,0233092 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,01274983 0,02329126 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,01274983 0,02327334 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,01274983 0,02325545 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,01274983 0,02323759 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01274983 0,02321975 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,01274983 0,02320195 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,01274983 0,02318417 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,01274983 0,02316642 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01274983 0,02314869 ! response to osmotic stress GO:0006970 23 15 0,000 0,01274983 0,02313099 ! vesicle coating GO:0006901 26 15 0,000 0,01274983 0,02311332 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,01274983 0,02309568 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,01274983 0,02307806 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,01274983 0,02306047 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,01274983 0,02304291 ! bone mineralization GO:0030282 17 15 0,000 0,01274983 0,02302537 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,01274983 0,02300786 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,01274983 0,02299038 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,01274983 0,02297292 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,01274983 0,02295549 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,01274983 0,02293809 ! regulation of cellular pH GO:0030641 23 15 0,000 0,01274983 0,02292071 ! ribosome assembly GO:0042255 17 15 0,000 0,01274983 0,02290336 ! cerebellum development GO:0021549 19 15 0,000 0,01274983 0,02288604 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,01274983 0,02286874 ! mRNA splice site selection GO:0006376 33 15 0,000 0,01274983 0,02285147 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,01274983 0,02283422 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,01274983 0,022817 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,01274983 0,0227998 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,01274983 0,02278264 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,01274983 0,02276549 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,01274983 0,02274838 ! muscle maintenance GO:0046716 21 15 0,000 0,01274983 0,02273129 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,01274983 0,02271422 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,01274983 0,02269718 ! intestinal absorption GO:0050892 22 15 0,000 0,01274983 0,02268017 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,01274983 0,02266318 ! dopamine metabolic process GO:0042417 32 15 0,000 0,01274983 0,02264621 ! gas transport GO:0015669 23 15 0,000 0,01274983 0,02262928 ! regulation of RNA stability GO:0043487 31 15 0,000 0,01274983 0,02261236 ! organic cation transport GO:0015695 19 15 0,000 0,01274983 0,02259547 ! heme biosynthetic process GO:0006783 22 15 0,000 0,01274983 0,02257861 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,01274983 0,02256178 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,01274983 0,02254496 ! release of cytochrome c from mitochondria GO:0001836 29 15 0,000 0,01274983 0,02252818 ! cilium assembly GO:0042384 22 15 0,000 0,01274983 0,02251141 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,01274983 0,02249468 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,01274983 0,02247796 ! peptide hormone processing GO:0016486 23 15 0,000 0,01274983 0,02246128 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,01274983 0,02244461 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,01359435 0,02391357 ! bone remodeling GO:0046849 24 16 0,000 0,01359435 0,02389585 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,01359435 0,02387816 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,01359435 0,0238605 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,01359435 0,02384287 ! bile acid metabolic process GO:0008206 23 16 0,000 0,01359435 0,02382526 ! axis specification GO:0009798 26 16 0,000 0,01359435 0,02380767 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,01359435 0,02379012 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,01359435 0,02377259 ! positive regulation of cell growth GO:0030307 22 16 0,000 0,01359435 0,02375508 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01359435 0,0237376 ! centrosome cycle GO:0007098 18 16 0,000 0,01359435 0,02372015 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,01359435 0,02370272 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,01359435 0,02368532 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,01359435 0,02366794 ! cellular response to starvation GO:0009267 26 16 0,000 0,01359435 0,02365059 ! DNA integration GO:0015074 25 16 0,000 0,01359435 0,02363326 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,01359435 0,02361596 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,01359435 0,02359868 ! regulation of exocytosis GO:0017157 28 16 0,000 0,01359435 0,02358143 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,01359435 0,02356421 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,01359435 0,02354701 ! regulation of vasodilation GO:0042312 26 16 0,000 0,01359435 0,02352983 ! DNA replication initiation GO:0006270 26 16 0,000 0,01359435 0,02351268 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,01359435 0,02349556 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,01359435 0,02347846 ! neuron recognition GO:0008038 27 16 0,000 0,01359435 0,02346138 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,01359435 0,02344433 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,01359435 0,02342731 ! G1 phase GO:0051318 28 16 0,000 0,01359435 0,0234103 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01359435 0,02339333 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,01359435 0,02337638 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,01359435 0,02335945 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,01359435 0,02334255 ! NADP metabolic process GO:0006739 22 16 0,000 0,01359435 0,02332567 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,01359435 0,02330881 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,01359435 0,02329199 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,01359435 0,02327518 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,01359435 0,0232584 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01359435 0,02324164 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,01359435 0,02322491 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,01359435 0,0232082 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,01359435 0,02319152 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,01359435 0,02317486 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,01359435 0,02315822 ! defense response to virus GO:0051607 28 16 0,000 0,01359435 0,02314161 ! peptide hormone secretion GO:0030072 26 16 0,000 0,01359435 0,02312502 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,0144382 0,02454287 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,0144382 0,0245253 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,0144382 0,02450776 ! zinc ion transport GO:0006829 22 17 0,000 0,0144382 0,02449024 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,0144382 0,02447275 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,0144382 0,02445528 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,0144382 0,02443783 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,0144382 0,02442042 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,0144382 0,02440302 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,0144382 0,02438565 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,0144382 0,02436831 ! adult walking behavior GO:0007628 30 17 0,000 0,0144382 0,02435099 ! patterning of blood vessels GO:0001569 27 17 0,000 0,0144382 0,0243337 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,0144382 0,02431643 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,0144382 0,02429918 GO:0042744|hydrogen peroxide catabolic process, ! retinoid metabolic process GO:0001523 22 17 0,000 0,0144382 0,02428196 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,0144382 0,02426476 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,0144382 0,02424759 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,0144382 0,02423044 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0144382 0,02421332 ! protein polyubiquitination GO:0000209 31 17 0,000 0,0144382 0,02419622 ! cerebral cortex development GO:0021987 34 17 0,000 0,0144382 0,02417914 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,0144382 0,02416209 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0144382 0,02414506 ! fructose metabolic process GO:0006000 24 17 0,000 0,0144382 0,02412806 ! membrane budding GO:0006900 30 17 0,000 0,0144382 0,02411108 ! neuromuscular junction development GO:0007528 25 17 0,000 0,0144382 0,02409412 ! L-amino acid transport GO:0015807 27 17 0,000 0,0144382 0,02407719 ! regulation of protein binding GO:0043393 29 17 0,000 0,0144382 0,02406028 ! peptide secretion GO:0002790 30 17 0,000 0,0144382 0,0240434 ! stem cell differentiation GO:0048863 40 17 0,000 0,0144382 0,02402654 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,0144382 0,0240097 ! intermediate filament-based process GO:0045103 29 17 0,000 0,0144382 0,02399289 ! protein export from nucleus GO:0006611 26 17 0,000 0,0144382 0,0239761 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,0144382 0,02395933 ! diencephalon development GO:0021536 27 17 0,000 0,0144382 0,02394259 ! oogenesis GO:0048477 25 17 0,000 0,0144382 0,02392587 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,0144382 0,02390917 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,0144382 0,0238925 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,0144382 0,02387585 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,0144382 0,02385922 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,0144382 0,02384262 ! steroid catabolic process GO:0006706 24 17 0,000 0,0144382 0,02382604 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,0144382 0,02380948 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,0144382 0,02379295 ! nerve development GO:0021675 20 17 0,000 0,0144382 0,02377644 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,0144382 0,02375995 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,0144382 0,02374348 ! protein secretion GO:0009306 32 18 0,000 0,01528136 0,02511266 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,01528136 0,02509528 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,01528136 0,02507792 ! negative regulation of defense response GO:0031348 21 18 0,000 0,01528136 0,02506059 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,01528136 0,02504329 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,01528136 0,025026 ! metencephalon development GO:0022037 25 18 0,000 0,01528136 0,02500874 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,01528136 0,02499151 ! hormone secretion GO:0046879 28 18 0,000 0,01528136 0,0249743 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,01528136 0,02495711 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,01528136 0,02493994 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,01528136 0,0249228 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01528136 0,02490569 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,01528136 0,02488859 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,01528136 0,02487152 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01528136 0,02485447 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,01528136 0,02483745 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,01528136 0,02482045 ! glial cell development GO:0021782 31 18 0,000 0,01528136 0,02480347 ! keratinization GO:0031424 19 18 0,000 0,01528136 0,02478652 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,01528136 0,02476959 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,01528136 0,02475268 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,01528136 0,0247358 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,01528136 0,02471893 ! vacuolar transport GO:0007034 26 18 0,000 0,01528136 0,0247021 ! pigmentation during development GO:0048066 35 18 0,000 0,01528136 0,02468528 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,01528136 0,02466849 ! fucose metabolic process GO:0006004 27 18 0,000 0,01528136 0,02465172 ! actin filament bundle formation GO:0051017 30 18 0,000 0,01528136 0,02463497 ! body fluid secretion GO:0007589 27 18 0,000 0,01528136 0,02461825 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,01528136 0,02460155 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,01528136 0,02458487 ! negative regulation of immune response GO:0050777 33 18 0,000 0,01528136 0,02456821 ! heart process GO:0003015 32 18 0,000 0,01528136 0,02455158 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,01528136 0,02453496 ! sensory perception of pain GO:0019233 26 18 0,000 0,01528136 0,02451838 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,01528136 0,02450181 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,01528136 0,02448526 ! somitogenesis GO:0001756 25 18 0,000 0,01528136 0,02446874 ! neural crest cell migration GO:0001755 28 18 0,000 0,01528136 0,02445224 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,01528136 0,02443577 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,01528136 0,02441931 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,01528136 0,02440288 ! synaptogenesis GO:0007416 28 18 0,000 0,01528136 0,02438647 ! cell-cell junction organization GO:0045216 28 18 0,000 0,01528136 0,02437008 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01528136 0,02435371 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,01528136 0,02433737 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,01528136 0,02432104 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,01528136 0,02430474 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,01528136 0,02428846 ! gut development GO:0048565 29 18 0,000 0,01528136 0,02427221 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,01528136 0,02425597 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,01528136 0,02423976 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,01528136 0,02422357 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,01612385 0,02554199 ! positive regulation of translation GO:0045727 29 19 0,000 0,01612385 0,02552495 ! positive regulation of cell size GO:0045793 26 19 0,000 0,01612385 0,02550793 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,01612385 0,02549094 ! glycerol metabolic process GO:0006071 22 19 0,000 0,01612385 0,02547397 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,01612385 0,02545702 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,01612385 0,02544009 ! endothelial cell migration GO:0043542 24 19 0,000 0,01612385 0,02542319 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,01612385 0,02540631 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,01612385 0,02538945 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,01612385 0,02537261 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,01612385 0,0253558 ! pancreas development GO:0031016 27 19 0,000 0,01612385 0,02533901 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,01612385 0,02532224 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,01612385 0,02530549 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,01612385 0,02528876 ! central nervous system neuron development GO:0021954 33 19 0,000 0,01612385 0,02527206 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,01612385 0,02525538 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,01612385 0,02523872 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,01612385 0,02522208 ! heme metabolic process GO:0042168 29 19 0,000 0,01612385 0,02520547 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,01612385 0,02518887 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,01612385 0,0251723 ! response to fungus GO:0009620 21 19 0,000 0,01612385 0,02515575 ! peptide cross-linking GO:0018149 35 19 0,000 0,01612385 0,02513922 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,01612385 0,02512272 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,01612385 0,02510623 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,01612385 0,02508977 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,01612385 0,02507333 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,01612385 0,02505691 ! vitamin transport GO:0051180 26 19 0,000 0,01612385 0,02504051 ! sarcomere organization GO:0045214 26 19 0,000 0,01612385 0,02502413 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,01612385 0,02500778 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,01612385 0,02499144 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,01612385 0,02497513 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,01612385 0,02495884 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,01612385 0,02494257 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,01612385 0,02492632 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,01696566 0,02621062 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,01696566 0,02619357 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,01696566 0,02617654 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,01696566 0,02615953 ! lipid phosphorylation GO:0046834 28 20 0,000 0,01696566 0,02614254 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,01696566 0,02612557 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,01696566 0,02610863 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,01696566 0,02609171 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,01696566 0,02607481 ! response to alkaloid GO:0043279 34 20 0,000 0,01696566 0,02605794 ! sensory perception of taste GO:0050909 26 20 0,000 0,01696566 0,02604108 ! response to retinoic acid GO:0032526 27 20 0,000 0,01696566 0,02602425 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,01696566 0,02600744 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,01696566 0,02599065 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,01696566 0,02597388 ! chromosome condensation GO:0030261 32 20 0,000 0,01696566 0,02595713 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,01696566 0,02594041 ! sex determination GO:0007530 32 20 0,000 0,01696566 0,0259237 ! plasma membrane fusion GO:0045026 24 20 0,000 0,01696566 0,02590702 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,01696566 0,02589036 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,01696566 0,02587372 ! cytolysis GO:0019835 21 20 0,000 0,01696566 0,0258571 ! renal system process GO:0003014 35 20 0,000 0,01696566 0,02584051 ! vasodilation GO:0042311 36 20 0,000 0,01696566 0,02582393 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,01696566 0,02580738 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,01696566 0,02579085 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,01696566 0,02577433 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,01696566 0,02575784 ! hormone transport GO:0009914 30 20 0,000 0,01696566 0,02574138 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,01696566 0,02572493 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,01696566 0,0257085 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,01696566 0,02569209 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,01696566 0,02567571 ! sperm-egg recognition GO:0035036 24 20 0,000 0,01696566 0,02565934 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,01696566 0,025643 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,01696566 0,02562668 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,01780679 0,0268801 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,01780679 0,02686301 ! positive regulation of fibroblast proliferation GO:0048146 30 21 0,000 0,01780679 0,02684594 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,01780679 0,0268289 ! positive regulation of ossification GO:0045778 34 21 0,000 0,01780679 0,02681187 ! iron ion transport GO:0006826 49 21 0,000 0,01780679 0,02679487 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,01780679 0,02677789 ! microtubule-based transport GO:0010970 41 21 0,000 0,01780679 0,02676093 ! vesicle docking GO:0048278 28 21 0,000 0,01780679 0,026744 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,01780679 0,02672708 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,01780679 0,02671019 ! apoptotic mitochondrial changes GO:0008637 42 21 0,000 0,01780679 0,02669331 ! response to ethanol GO:0045471 38 21 0,000 0,01780679 0,02667646 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,01780679 0,02665963 ! smooth muscle contraction GO:0006939 39 21 0,000 0,01780679 0,02664282 ! response to vitamin A GO:0033189 28 21 0,000 0,01780679 0,02662603 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,01780679 0,02660927 GO:0042278|purine nucleoside metabolic process, ! apoptotic nuclear changes GO:0030262 31 21 0,000 0,01780679 0,02659252 ! response to starvation GO:0042594 35 21 0,000 0,01780679 0,02657579 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,01780679 0,02655909 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,01780679 0,02654241 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,01780679 0,02652575 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,01780679 0,02650911 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,01780679 0,02649249 ! visual learning GO:0008542 38 21 0,000 0,01780679 0,02647589 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 0,000 0,01780679 0,02645931 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,01780679 0,02644275 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,01780679 0,02642621 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,01780679 0,0264097 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,01780679 0,0263932 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,01780679 0,02637673 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,01780679 0,02636027 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,01780679 0,02634384 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,01780679 0,02632742 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,01780679 0,02631103 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,01780679 0,02629466 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,01780679 0,0262783 ! embryonic pattern specification GO:0009880 34 22 0,000 0,01864724 0,0275015 ! regulation of cell killing GO:0031341 37 22 0,000 0,01864724 0,02748442 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,01864724 0,02746736 ! gluconeogenesis GO:0006094 26 22 0,000 0,01864724 0,02745032 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,01864724 0,0274333 ! viral genome replication GO:0019079 31 22 0,000 0,01864724 0,0274163 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,01864724 0,02739932 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,01864724 0,02738237 ! protein amino acid acylation GO:0043543 42 22 0,000 0,01864724 0,02736544 ! response to vitamin GO:0033273 31 22 0,000 0,01864724 0,02734852 ! molting cycle process GO:0022404 43 22 0,000 0,01864724 0,02733163 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,01864724 0,02731476 ! regeneration GO:0031099 37 22 0,000 0,01864724 0,02729791 ! phototransduction GO:0007602 29 22 0,000 0,01864724 0,02728108 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,01864724 0,02726427 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,01864724 0,02724748 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,01864724 0,02723071 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,01864724 0,02721397 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,01864724 0,02719724 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,01864724 0,02718053 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,01864724 0,02716385 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,01864724 0,02714718 ! pallium development GO:0021543 43 22 0,000 0,01864724 0,02713054 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,01864724 0,02711392 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,01864724 0,02709731 ! platelet activation GO:0030168 33 22 0,000 0,01864724 0,02708073 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,01864724 0,02706416 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,01864724 0,02704762 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,01864724 0,0270311 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,01864724 0,0270146 ! cell-cell recognition GO:0009988 28 22 0,000 0,01864724 0,02699811 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,01864724 0,02698165 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,01864724 0,02696521 ! alditol metabolic process GO:0019400 26 22 0,000 0,01864724 0,02694879 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,01864724 0,02693239 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,01948702 0,02812816 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,01948702 0,02811106 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,01948702 0,02809398 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,01948702 0,02807693 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,01948702 0,02805989 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,01948702 0,02804287 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,01948702 0,02802588 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,01948702 0,0280089 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,01948702 0,02799195 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,01948702 0,02797501 ! dendrite development GO:0016358 41 23 0,000 0,01948702 0,0279581 ! vasculogenesis GO:0001570 38 23 0,000 0,01948702 0,02794121 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,01948702 0,02792433 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,01948702 0,02790748 ! lysosome organization GO:0007040 41 23 0,000 0,01948702 0,02789065 ! digestive system process GO:0022600 35 23 0,000 0,01948702 0,02787384 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,01948702 0,02785705 ! vesicle targeting GO:0006903 35 23 0,000 0,01948702 0,02784028 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,01948702 0,02782353 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,01948702 0,02780679 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,01948702 0,02779008 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,01948702 0,02777339 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,01948702 0,02775672 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,01948702 0,02774007 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,01948702 0,02772344 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,01948702 0,02770683 ! membrane depolarization GO:0051899 40 23 0,000 0,01948702 0,02769024 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,01948702 0,02767367 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,01948702 0,02765712 ! DNA modification GO:0006304 33 23 0,000 0,01948702 0,02764059 ! collagen fibril organization GO:0030199 50 23 0,000 0,01948702 0,02762407 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,01948702 0,02760758 ! cellular response to extracellular stimulus GO:0031668 37 23 0,000 0,01948702 0,02759111 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,01948702 0,02757466 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,01948702 0,02755822 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,01948702 0,02754181 ! positive regulation of B cell activation GO:0050871 36 23 0,000 0,01948702 0,02752542 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,01948702 0,02750904 ! collagen catabolic process GO:0030574 29 23 0,000 0,01948702 0,02749269 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,01948702 0,02747635 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,01948702 0,02746003 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,01948702 0,02744374 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,01948702 0,02742746 ! blastocyst development GO:0001824 41 23 0,000 0,01948702 0,0274112 ! actin filament-based movement GO:0030048 37 23 0,000 0,01948702 0,02739496 ! protein stabilization GO:0050821 34 23 0,000 0,01948702 0,02737874 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,02032612 0,02854076 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,02032612 0,02852388 ! myelination GO:0042552 39 24 0,000 0,02032612 0,02850702 ! initiation of viral infection GO:0019059 47 24 0,000 0,02032612 0,02849018 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,02032612 0,02847337 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,02032612 0,02845657 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,02032612 0,02843979 ! visual behavior GO:0007632 42 24 0,000 0,02032612 0,02842303 ! spinal cord development GO:0021510 41 24 0,000 0,02032612 0,02840629 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,02032612 0,02838957 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 0,000 0,02032612 0,02837287 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,02032612 0,02835619 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,02032612 0,02833953 ! cell aging GO:0007569 38 24 0,000 0,02032612 0,02832289 ! osteoblast differentiation GO:0001649 43 24 0,000 0,02032612 0,02830627 ! response to toxin GO:0009636 38 24 0,000 0,02032612 0,02828967 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,02032612 0,02827308 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,02032612 0,02825652 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,02032612 0,02823998 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,02032612 0,02822345 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,02032612 0,02820695 ! pentose metabolic process GO:0019321 33 24 0,000 0,02032612 0,02819046 ! immunoglobulin production GO:0002377 37 24 0,000 0,02032612 0,028174 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,02032612 0,02815755 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,02032612 0,02814112 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,02032612 0,02812471 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,02032612 0,02810832 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,02032612 0,02809195 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,02032612 0,0280756 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,02032612 0,02805927 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,02032612 0,02804296 ! regulation of fibroblast proliferation GO:0048145 39 25 0,000 0,02116454 0,02918272 ! neuron fate commitment GO:0048663 38 25 0,000 0,02116454 0,02916577 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,02116454 0,02914885 ! superoxide metabolic process GO:0006801 33 25 0,000 0,02116454 0,02913194 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,02116454 0,02911505 GO:0050908|detection of light stimulus involved in visual perception, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,02116454 0,02909818 ! vacuole organization GO:0007033 43 25 0,000 0,02116454 0,02908133 ! receptor metabolic process GO:0043112 40 25 0,000 0,02116454 0,0290645 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,02116454 0,02904769 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,02116454 0,0290309 ! regulation of behavior GO:0050795 45 25 0,000 0,02116454 0,02901413 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,02116454 0,02899738 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,02116454 0,02898065 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,02116454 0,02896393 ! negative regulation of phosphorylation GO:0042326 46 25 0,000 0,02116454 0,02894724 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,02116454 0,02893057 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,02116454 0,02891391 ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,02116454 0,02889727 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,02116454 0,02888066 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,02116454 0,02886406 ! regulation of amine transport GO:0051952 44 25 0,000 0,02116454 0,02884748 ! liver development GO:0001889 44 25 0,000 0,02116454 0,02883092 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,02200229 0,02995493 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,02200229 0,02993775 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,02200229 0,0299206 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,02200229 0,02990346 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,02200229 0,02988634 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,02200229 0,02986925 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,02200229 0,02985217 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,02200229 0,02983511 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,02200229 0,02981807 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,02200229 0,02980105 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,02200229 0,02978405 ! sperm motility GO:0030317 31 26 0,000 0,02200229 0,02976707 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,02200229 0,02975011 ! male gonad development GO:0008584 39 26 0,000 0,02200229 0,02973317 ! neural crest cell development GO:0014032 44 26 0,000 0,02200229 0,02971624 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,02200229 0,02969934 ! cell fate determination GO:0001709 54 26 0,000 0,02200229 0,02968246 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,02200229 0,02966559 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,02200229 0,02964875 ! detection of visible light GO:0009584 33 26 0,000 0,02200229 0,02963192 ! spermatid development GO:0007286 40 26 0,000 0,02200229 0,02961511 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,02200229 0,02959832 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,02200229 0,02958155 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,02200229 0,0295648 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,02200229 0,02954807 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02283937 0,03065487 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,02283937 0,03063755 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,02283937 0,03062024 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,02283937 0,03060295 ! membrane docking GO:0022406 40 27 0,000 0,02283937 0,03058568 ! circadian rhythm GO:0007623 44 27 0,000 0,02283937 0,03056842 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,02283937 0,03055119 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,02283937 0,03053398 ! autophagy GO:0006914 36 27 0,000 0,02283937 0,03051679 ! myofibril assembly GO:0030239 40 27 0,000 0,02283937 0,03049962 GO:0055002|striated muscle cell development, ! negative regulation of phosphorus metabolic process GO:0010563 51 27 0,000 0,02283937 0,03048246 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,02283937 0,03046533 ! peptide transport GO:0015833 46 27 0,000 0,02283937 0,03044821 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,02283937 0,03043112 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,02283937 0,03041404 ! negative regulation of cell development GO:0010721 67 27 0,000 0,02283937 0,03039698 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,02283937 0,03037994 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,02283937 0,03036292 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,02283937 0,03034592 ! detection of light stimulus GO:0009583 35 27 0,000 0,02283937 0,03032894 ! lipid oxidation GO:0034440 39 27 0,000 0,02283937 0,03031198 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,02283937 0,03029503 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,02283937 0,03027811 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,02283937 0,0302612 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,02367577 0,03135189 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,02367577 0,03133441 ! translational initiation GO:0006413 48 28 0,000 0,02367577 0,03131694 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,02367577 0,03129949 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,02367577 0,03128207 ! regulation of pH GO:0006885 40 28 0,000 0,02367577 0,03126466 ! catechol metabolic process GO:0009712 46 28 0,000 0,02367577 0,03124727 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,02367577 0,0312299 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,02367577 0,03121255 ! iron ion homeostasis GO:0055072 49 28 0,000 0,02367577 0,03119522 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,02367577 0,03117791 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,02367577 0,03116062 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,02367577 0,03114334 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,02367577 0,03112609 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,02367577 0,03110886 ! gene silencing GO:0016458 47 28 0,000 0,02367577 0,03109164 ! regulation of coagulation GO:0050818 42 28 0,000 0,02367577 0,03107444 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,02451149 0,03215355 ! phenol metabolic process GO:0018958 47 29 0,000 0,02451149 0,03213578 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,02451149 0,03211804 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,02451149 0,03210031 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,02451149 0,03208261 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,02451149 0,03206492 ! cholesterol transport GO:0030301 48 29 0,000 0,02451149 0,03204726 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,02451149 0,03202961 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,02451149 0,03201198 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,02451149 0,03199437 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,02451149 0,03197678 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,02451149 0,03195921 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,02451149 0,03194166 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,02451149 0,03192413 ! response to ionizing radiation GO:0010212 55 29 0,000 0,02451149 0,03190662 ! muscle cell development GO:0055001 42 29 0,000 0,02451149 0,03188913 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,02451149 0,03187165 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,02451149 0,0318542 ! mesoderm formation GO:0001707 52 29 0,000 0,02451149 0,03183677 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,02451149 0,03181935 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,02451149 0,03180195 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,02451149 0,03178457 ! ensheathment of neurons GO:0007272 48 29 0,000 0,02451149 0,03176721 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,02451149 0,03174987 ! spermatid differentiation GO:0048515 45 29 0,000 0,02451149 0,03173255 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,02451149 0,03171525 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,02534654 0,03277785 ! organic anion transport GO:0015711 50 30 0,000 0,02534654 0,03275999 ! acute-phase response GO:0006953 49 30 0,000 0,02534654 0,03274216 ! segmentation GO:0035282 43 30 0,000 0,02534654 0,03272435 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,02534654 0,03270655 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,02534654 0,03268878 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,02534654 0,03267102 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,02534654 0,03265328 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,02534654 0,03263557 ! formation of primary germ layer GO:0001704 54 30 0,000 0,02534654 0,03261787 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,02534654 0,03260019 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,02534654 0,03258253 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,02534654 0,03256489 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,02534654 0,03254727 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,02534654 0,03252966 ! response to heat GO:0009408 43 30 0,000 0,02534654 0,03251208 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,02534654 0,03249452 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,02618092 0,03354608 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,02618092 0,03352797 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,02618092 0,03350989 ! regulation of innate immune response GO:0045088 42 31 0,000 0,02618092 0,03349182 ! ovulation cycle process GO:0022602 46 31 0,000 0,02618092 0,03347378 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,02618092 0,03345575 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,02618092 0,03343775 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,02618092 0,03341976 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,02618092 0,03340179 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,02618092 0,03338384 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,02618092 0,03336591 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,02618092 0,033348 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,02618092 0,03333011 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,02618092 0,03331224 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,02618092 0,03329439 ! tissue homeostasis GO:0001894 45 31 0,000 0,02618092 0,03327656 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,02701463 0,03431784 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,02701463 0,03429948 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,02701463 0,03428113 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,02701463 0,03426281 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,02701463 0,03424451 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,02701463 0,03422622 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,02701463 0,03420796 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,02701463 0,03418972 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,02701463 0,03417149 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,02701463 0,03415329 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,02701463 0,0341351 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,02701463 0,03411693 ! telencephalon development GO:0021537 59 32 0,000 0,02701463 0,03409879 ! ovulation cycle GO:0042698 48 32 0,000 0,02701463 0,03408066 ! cofactor catabolic process GO:0051187 52 32 0,000 0,02701463 0,03406255 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,02701463 0,03404446 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,02701463 0,03402639 ! placenta development GO:0001890 45 32 0,000 0,02701463 0,03400834 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,02701463 0,03399031 ! vesicle localization GO:0051648 50 32 0,000 0,02701463 0,03397229 ! regulation of muscle development GO:0048634 52 33 0,000 0,02784767 0,03500133 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,02784767 0,0349828 ! negative regulation of secretion GO:0051048 53 33 0,000 0,02784767 0,03496429 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,02784767 0,0349458 ! glial cell differentiation GO:0010001 65 33 0,000 0,02784767 0,03492733 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,02784767 0,03490888 ! sister chromatid segregation GO:0000819 48 33 0,000 0,02784767 0,03489045 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,02784767 0,03487204 ! spindle organization GO:0007051 39 33 0,000 0,02784767 0,03485365 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,02784767 0,03483527 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,02784767 0,03481692 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,02784767 0,03479858 ! protein targeting to membrane GO:0006612 63 33 0,000 0,02784767 0,03478027 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,02784767 0,03476197 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,02784767 0,0347437 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,02784767 0,03472544 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,02784767 0,0347072 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,02784767 0,03468898 ! cytokine production GO:0001816 49 33 0,000 0,02784767 0,03467078 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,02784767 0,0346526 ! RNA modification GO:0009451 43 33 0,000 0,02784767 0,03463444 ! regulation of B cell activation GO:0050864 55 33 0,000 0,02784767 0,0346163 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,02784767 0,03459817 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,02868003 0,03561366 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,02868003 0,03559504 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,02868003 0,03557643 ! actomyosin structure organization GO:0031032 48 34 0,000 0,02868003 0,03555784 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,02868003 0,03553928 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,02868003 0,03552073 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,02868003 0,0355022 ! positive regulation of cell development GO:0010720 58 34 0,000 0,02868003 0,03548369 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,02868003 0,0354652 ! cell fate specification GO:0001708 49 34 0,000 0,02868003 0,03544673 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 0,000 0,02868003 0,03542827 ! peripheral nervous system development GO:0007422 58 34 0,000 0,02868003 0,03540984 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,02868003 0,03539143 ! adult locomotory behavior GO:0008344 54 34 0,000 0,02868003 0,03537303 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,02868003 0,03535466 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,02951172 0,03636102 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,02951172 0,03634215 ! collagen metabolic process GO:0032963 47 35 0,000 0,02951172 0,0363233 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,02951172 0,03630447 ! metanephros development GO:0001656 61 35 0,000 0,02951172 0,03628566 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,02951172 0,03626687 ! female gonad development GO:0008585 55 35 0,000 0,02951172 0,0362481 ! lipid homeostasis GO:0055088 63 35 0,000 0,02951172 0,03622934 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,02951172 0,03621061 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,02951172 0,0361919 ! hindbrain development GO:0030902 56 35 0,000 0,02951172 0,0361732 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,02951172 0,03615453 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,02951172 0,03613587 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,02951172 0,03611724 ! embryonic organ development GO:0048568 53 35 0,000 0,02951172 0,03609862 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,02951172 0,03608002 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,02951172 0,03606144 ! meiosis I GO:0007127 61 36 0,000 0,03034275 0,03705782 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,03034275 0,03703875 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,03034275 0,03701971 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,03034275 0,03700069 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,03034275 0,03698168 ! spliceosome assembly GO:0000245 65 36 0,000 0,03034275 0,0369627 ! mismatch repair GO:0006298 42 36 0,000 0,03034275 0,03694373 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,03034275 0,03692479 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,03034275 0,03690586 ! regulation of proteolysis GO:0030162 53 36 0,000 0,03034275 0,03688696 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,03034275 0,03686807 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,03034275 0,0368492 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,03034275 0,03683035 ! eye morphogenesis GO:0048592 64 36 0,000 0,03034275 0,03681152 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,03034275 0,03679271 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,0311731 0,03778027 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,0311731 0,03776098 ! mammary gland development GO:0030879 73 37 0,000 0,0311731 0,03774172 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,0311731 0,03772247 ! ear morphogenesis GO:0042471 50 37 0,000 0,0311731 0,03770325 ! odontogenesis GO:0042476 60 37 0,000 0,0311731 0,03768404 ! negative regulation of binding GO:0051100 59 37 0,000 0,0311731 0,03766485 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,0311731 0,03764568 ! tissue remodeling GO:0048771 65 37 0,000 0,0311731 0,03762653 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,0311731 0,03760741 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 58 37 0,000 0,0311731 0,0375883 ! keratinocyte differentiation GO:0030216 55 37 0,000 0,0311731 0,03756921 ! natural killer cell activation GO:0030101 45 37 0,000 0,0311731 0,03755014 ! polyol metabolic process GO:0019751 47 37 0,000 0,0311731 0,03753108 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,0311731 0,03751205 ! glucan metabolic process GO:0044042 54 37 0,000 0,0311731 0,03749304 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,03200278 0,03847143 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,03200278 0,03845195 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,03200278 0,03843249 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,03200278 0,03841305 ! feeding behavior GO:0007631 50 38 0,000 0,03200278 0,03839363 ! organic ether metabolic process GO:0018904 51 38 0,000 0,03200278 0,03837423 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,03200278 0,03835485 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,03200278 0,03833549 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,03200278 0,03831615 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,03200278 0,03829683 ! ion transmembrane transport GO:0034220 58 38 0,000 0,03200278 0,03827752 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,03200278 0,03825824 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,03200278 0,03823898 ! neuron migration GO:0001764 59 38 0,000 0,03200278 0,03821973 ! maintenance of protein location GO:0045185 72 38 0,000 0,03200278 0,03820051 ! pigment metabolic process GO:0042440 66 38 0,000 0,03200278 0,0381813 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,03200278 0,03816211 ! mRNA catabolic process GO:0006402 58 39 0,000 0,0328318 0,03913102 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,0328318 0,03911138 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,0328318 0,03909175 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,0328318 0,03907215 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,0328318 0,03905256 ! regulation of protein stability GO:0031647 58 39 0,000 0,0328318 0,039033 ! female gamete generation GO:0007292 50 39 0,000 0,0328318 0,03901345 ! aerobic respiration GO:0009060 56 39 0,000 0,0328318 0,03899392 ! positive regulation of leukocyte proliferation GO:0070665 64 39 0,000 0,0328318 0,03897442 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,0328318 0,03895493 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,03366015 0,0399178 ! Notch signaling pathway GO:0007219 64 40 0,000 0,03366015 0,03989787 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,03366015 0,03987795 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,03366015 0,03985805 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,03366015 0,03983817 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,03366015 0,03981831 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,03366015 0,03979847 ! phagocytosis GO:0006909 65 40 0,000 0,03366015 0,03977865 ! mesenchymal cell development GO:0014031 70 40 0,000 0,03366015 0,03975885 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,03366015 0,03973907 ! B cell differentiation GO:0030183 70 40 0,000 0,03366015 0,03971931 ! pigmentation GO:0043473 81 40 0,000 0,03366015 0,03969957 ! developmental growth GO:0048589 70 40 0,000 0,03366015 0,03967984 ! synapse organization GO:0050808 61 40 0,000 0,03366015 0,03966014 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,03448783 0,04061519 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,03448783 0,04059504 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,03448783 0,04057492 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,03448783 0,04055481 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,03448783 0,04053473 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,03448783 0,04051466 ! cell growth GO:0016049 71 41 0,000 0,03448783 0,04049461 ! maintenance of location in cell GO:0051651 77 41 0,000 0,03448783 0,04047458 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,03531484 0,04142467 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,03531484 0,0414042 ! learning GO:0007612 75 42 0,000 0,03531484 0,04138376 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,03531484 0,04136333 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,03531484 0,04134293 ! gliogenesis GO:0042063 85 42 0,000 0,03531484 0,04132254 ! endosome transport GO:0016197 74 42 0,000 0,03531484 0,04130217 ! induction of apoptosis by intracellular signals GO:0008629 78 42 0,000 0,03531484 0,04128183 ! male sex differentiation GO:0046661 62 42 0,000 0,03531484 0,0412615 ! double-strand break repair GO:0006302 75 42 0,000 0,03531484 0,0412412 ! epidermal cell differentiation GO:0009913 61 42 0,000 0,03531484 0,04122091 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,03531484 0,04120064 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,03531484 0,0411804 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,03614118 0,04212329 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,03614118 0,04210262 ! regulation of tube size GO:0035150 69 43 0,000 0,03614118 0,04208196 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,03614118 0,04206132 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,03614118 0,0420407 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,03614118 0,0420201 ! T cell differentiation GO:0030217 78 43 0,000 0,03614118 0,04199952 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,03614118 0,04197897 ! amino acid activation GO:0043038 61 43 0,000 0,03614118 0,04195843 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,03614118 0,04193791 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,03696686 0,04287506 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,03696686 0,04285411 ! cellular component disassembly GO:0022411 66 44 0,000 0,03696686 0,04283319 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,03696686 0,04281228 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,03696686 0,0427914 ! inner ear development GO:0048839 66 44 0,000 0,03696686 0,04277053 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,03696686 0,04274969 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,03696686 0,04272887 ! chromatin remodeling GO:0006338 73 44 0,000 0,03696686 0,04270806 ! biopolymer methylation GO:0043414 67 44 0,000 0,03696686 0,04268728 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,03696686 0,04266652 ! JNK cascade GO:0007254 66 44 0,000 0,03696686 0,04264578 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,03696686 0,04262506 ! regulation of cell shape GO:0008360 83 44 0,000 0,03696686 0,04260435 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,03779188 0,04353404 ! positive regulation of binding GO:0051099 67 45 0,000 0,03779188 0,04351292 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,03779188 0,04349181 ! regulation of ion transport GO:0043269 60 45 0,000 0,03779188 0,04347073 ! glucose transport GO:0015758 60 45 0,000 0,03779188 0,04344967 ! neuromuscular process GO:0050905 89 45 0,000 0,03779188 0,04342863 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,03779188 0,04340761 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,03779188 0,04338661 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,03779188 0,04336563 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,03861622 0,04429014 ! regulation of translational initiation GO:0006446 70 46 0,000 0,03861622 0,04426874 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,03861622 0,04424737 ! regulation of action potential GO:0001508 80 46 0,000 0,03861622 0,04422601 ! hexose transport GO:0008645 62 46 0,000 0,03861622 0,04420468 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,03861622 0,04418336 ! excretion GO:0007588 72 46 0,000 0,03861622 0,04416207 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,03861622 0,0441408 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,03861622 0,04411955 ! positive regulation of defense response GO:0031349 70 47 0,000 0,03943991 0,04503893 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,03943991 0,04501727 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,03943991 0,04499562 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,03943991 0,044974 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,03943991 0,0449524 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,03943991 0,04493082 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,04026293 0,04584641 ! viral infectious cycle GO:0019058 80 48 0,000 0,04026293 0,04582442 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,04026293 0,04580246 ! leukocyte migration GO:0050900 76 48 0,000 0,04026293 0,04578051 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,04026293 0,04575858 ! striated muscle contraction GO:0006941 78 48 0,000 0,04026293 0,04573668 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,04026293 0,0457148 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,04026293 0,04569293 ! tRNA processing GO:0008033 56 48 0,000 0,04026293 0,04567109 ! cell maturation GO:0048469 69 48 0,000 0,04026293 0,04564927 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,04026293 0,04562747 ! vesicle organization GO:0016050 87 48 0,000 0,04026293 0,04560569 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,04026293 0,04558393 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,04108528 0,04649279 ! glycolysis GO:0006096 63 49 0,000 0,04108528 0,04647063 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,04108528 0,04644849 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,04108528 0,04642637 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,04108528 0,04640427 ! response to temperature stimulus GO:0009266 66 49 0,000 0,04108528 0,04638219 ! endocrine system development GO:0035270 86 49 0,000 0,04108528 0,04636014 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,04108528 0,0463381 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,04108528 0,04631609 ! gastrulation GO:0007369 80 49 0,000 0,04108528 0,0462941 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,04108528 0,04627213 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,04108528 0,04625018 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,04108528 0,04622825 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,04108528 0,04620634 ! methylation GO:0032259 74 49 0,000 0,04108528 0,04618445 ! cell redox homeostasis GO:0045454 72 50 0,000 0,04190697 0,04708582 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,04190697 0,04706353 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,04190697 0,04704127 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,04190697 0,04701903 ! histone modification GO:0016570 81 50 0,000 0,04190697 0,04699681 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,04190697 0,04697461 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,04190697 0,04695243 ! regulation of mast cell proliferation GO:0070666 80 50 0,000 0,04190697 0,04693027 ! RNA catabolic process GO:0006401 77 51 0,000 0,042728 0,04782715 ! chloride transport GO:0006821 78 51 0,000 0,042728 0,0478046 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,042728 0,04778207 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,042728 0,04775956 ! regulation of ossification GO:0030278 82 51 0,000 0,042728 0,04773708 ! heart morphogenesis GO:0003007 71 51 0,000 0,042728 0,04771461 ! RNA elongation GO:0006354 67 51 0,000 0,042728 0,04769217 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,042728 0,04766975 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,04354837 0,04856216 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,04354837 0,04853935 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,04354837 0,04851656 ! regulation of DNA replication GO:0006275 88 52 0,000 0,04354837 0,0484938 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,04354837 0,04847105 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,04354837 0,04844833 ! covalent chromatin modification GO:0016569 90 52 0,000 0,04354837 0,04842562 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,04354837 0,04840294 ! proton transport GO:0015992 78 52 0,000 0,04354837 0,04838028 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,04354837 0,04835764 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,04354837 0,04833502 ! transition metal ion transport GO:0000041 88 53 0,000 0,04436808 0,04922181 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,04436808 0,0491988 ! muscle fiber development GO:0048747 80 53 0,000 0,04436808 0,04917583 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,04436808 0,04915287 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,04436808 0,04912993 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,04436808 0,04910702 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,04436808 0,04908412 ! regulation of endocytosis GO:0030100 71 53 0,000 0,04436808 0,04906125 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,04436808 0,0490384 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,04436808 0,04901557 ! regulation of leukocyte proliferation GO:0070663 88 53 0,000 0,04436808 0,04899276 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! maintenance of location GO:0051235 94 53 0,000 0,04436808 0,04896997 ! hydrogen transport GO:0006818 81 54 0,000 0,04518712 0,04985078 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,04518712 0,04982762 ! positive regulation of cell migration GO:0030335 100 54 0,000 0,04518712 0,04980447 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,04518712 0,04978135 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,04518712 0,04975825 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,04518712 0,04973517 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,04518712 0,04971212 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,04518712 0,04968908 ! germ cell development GO:0007281 82 54 0,000 0,04518712 0,04966607 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,04518712 0,04964307 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,04518712 0,0496201 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,0460055 0,0504954 ! ear development GO:0043583 83 55 0,000 0,0460055 0,05047206 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,0460055 0,05044873 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,0460055 0,05042543 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,0460055 0,05040215 ! regulation of actin filament length GO:0030832 88 56 0,000 0,04682323 0,05127435 ! positive regulation of secretion GO:0051047 83 56 0,000 0,04682323 0,0512507 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,04682323 0,05122707 ! DNA catabolic process GO:0006308 71 56 0,000 0,04682323 0,05120346 ! adult behavior GO:0030534 90 56 0,000 0,04682323 0,05117988 ! cartilage development GO:0051216 84 56 0,000 0,04682323 0,05115631 ! mesoderm development GO:0007498 84 57 0,000 0,04764029 0,05202504 ! aging GO:0007568 91 57 0,000 0,04764029 0,05200111 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,04764029 0,0519772 ! single fertilization GO:0007338 67 57 0,000 0,04764029 0,05195331 ! regulation of cellular component size GO:0032535 90 58 0,000 0,04845669 0,05281935 ! lipid modification GO:0030258 82 58 0,000 0,04845669 0,0527951 ! positive regulation of growth GO:0045927 78 58 0,000 0,04845669 0,05277087 ! DNA damage response, signal transduction GO:0042770 105 58 0,000 0,04845669 0,05274667 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,04845669 0,05272248 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,04927244 0,05358547 ! viral reproductive process GO:0022415 99 59 0,000 0,04927244 0,05356093 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,04927244 0,0535364 ! chromosome segregation GO:0007059 93 59 0,000 0,04927244 0,0535119 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,04927244 0,05348742 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,04927244 0,05346296 ! cell projection assembly GO:0030031 90 59 0,000 0,04927244 0,05343853 ! glucose catabolic process GO:0006007 78 60 0,000 0,05008753 0,05429772 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,05008753 0,05427292 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,05008753 0,05424815 ! kidney development GO:0001822 101 60 0,000 0,05008753 0,0542234 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,05008753 0,05419868 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,05090196 0,05505485 ! carbohydrate transport GO:0008643 83 61 0,000 0,05090196 0,05502977 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,05090196 0,05500471 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,05171573 0,05585864 ! amino acid transport GO:0006865 97 62 0,000 0,05171573 0,05583322 ! negative regulation of protein kinase activity GO:0006469 110 62 0,000 0,05171573 0,05580783 ! activation of MAPK activity GO:0000187 95 62 0,000 0,05171573 0,05578247 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,05171573 0,05575712 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,05171573 0,0557318 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,05171573 0,0557065 ! detection of external stimulus GO:0009581 78 62 0,000 0,05171573 0,05568123 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,05171573 0,05565598 ! secondary metabolic process GO:0019748 95 62 0,000 0,05171573 0,05563075 ! gonad development GO:0008406 91 62 0,000 0,05171573 0,05560554 ! exocytosis GO:0006887 91 63 0,000 0,05252885 0,05645423 ! negative regulation of kinase activity GO:0033673 112 63 0,000 0,05252885 0,05642868 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,05252885 0,05640314 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,05252885 0,05637763 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,05252885 0,05635215 ! regulation of heart contraction GO:0008016 104 63 0,000 0,05252885 0,05632668 ! developmental maturation GO:0021700 90 63 0,000 0,05252885 0,05630124 ! actin filament organization GO:0007015 107 64 0,000 0,0533413 0,05714624 ! fertilization GO:0009566 79 64 0,000 0,0533413 0,05712045 ! viral reproduction GO:0016032 104 64 0,000 0,0533413 0,05709468 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,0533413 0,05706894 ! amine catabolic process GO:0009310 100 65 0,000 0,05415311 0,05791137 ! negative regulation of cell growth GO:0030308 123 65 0,000 0,05415311 0,05788528 ! camera-type eye development GO:0043010 103 65 0,000 0,05415311 0,05785922 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,05415311 0,05783318 ! regulation of lipase activity GO:0060191 117 65 0,000 0,05415311 0,05780716 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,05415311 0,05778117 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,05496426 0,05862031 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,05496426 0,05859397 ! sensory perception of smell GO:0007608 81 66 0,000 0,05496426 0,05856766 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,05496426 0,05854137 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,05496426 0,05851511 ! lung development GO:0030324 112 66 0,000 0,05496426 0,05848887 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,05496426 0,05846265 ! B cell activation GO:0042113 119 66 0,000 0,05496426 0,05843646 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,05496426 0,05841029 ! negative regulation of transferase activity GO:0051348 117 66 0,000 0,05496426 0,05838415 ! negative regulation of cell size GO:0045792 125 67 0,000 0,05577475 0,05921856 ! neurotransmitter transport GO:0006836 92 67 0,000 0,05577475 0,05919208 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,05577475 0,05916562 ! appendage morphogenesis GO:0035107 103 67 0,000 0,05577475 0,05913918 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,05577475 0,05911277 ! extracellular matrix organization GO:0030198 117 67 0,000 0,05577475 0,05908638 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,05577475 0,05906001 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! meiosis GO:0007126 110 68 0,000 0,05658459 0,05989083 GO:0051327|M phase of meiotic cell cycle, ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,05658459 0,05986413 ! defense response to bacterium GO:0042742 79 68 0,000 0,05658459 0,05983745 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,05658459 0,05981079 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,05658459 0,05978416 ! activation of immune response GO:0002253 93 68 0,000 0,05658459 0,05975756 ! appendage development GO:0048736 108 69 0,000 0,05739378 0,06058516 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,05739378 0,06055822 ! urogenital system development GO:0001655 114 69 0,000 0,05739378 0,0605313 ! meiotic cell cycle GO:0051321 111 69 0,000 0,05739378 0,06050441 ! hexose catabolic process GO:0019320 95 70 0,000 0,05820231 0,06132952 ! adaptive immune response GO:0002250 102 70 0,000 0,05820231 0,0613023 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,05901019 0,06212563 ! cell-matrix adhesion GO:0007160 133 71 0,000 0,05901019 0,06209808 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,05901019 0,06207056 ! axon guidance GO:0007411 116 71 0,000 0,05901019 0,06204306 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,05901019 0,06201558 ! response to drug GO:0042493 115 72 0,000 0,05981742 0,06283609 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,05981742 0,06280829 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,05981742 0,06278051 ! respiratory system development GO:0060541 123 72 0,000 0,05981742 0,06275275 ! rhythmic process GO:0048511 113 72 0,000 0,05981742 0,06272502 ! regulation of immune effector process GO:0002697 121 72 0,000 0,05981742 0,06269732 ! humoral immune response GO:0006959 93 73 0,000 0,06062399 0,06351467 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,06062399 0,06348664 ! acute inflammatory response GO:0002526 107 74 0,000 0,06142992 0,06430225 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,06142992 0,06427389 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,06142992 0,06424557 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,06142992 0,06421726 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,06142992 0,06418899 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,06142992 0,06416074 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,06223519 0,06497321 ! inorganic anion transport GO:0015698 109 75 0,000 0,06223519 0,06494464 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,06223519 0,06491609 ! regulation of catabolic process GO:0009894 114 75 0,000 0,06223519 0,06488757 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,06303981 0,06569762 ! phosphoinositide-mediated signaling GO:0048015 122 76 0,000 0,06303981 0,06566878 ! cell-substrate adhesion GO:0031589 141 76 0,000 0,06303981 0,06563996 ! negative regulation of transport GO:0051051 122 77 0,000 0,06384379 0,06644794 ! response to nutrient GO:0007584 114 77 0,000 0,06384379 0,06641881 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,06384379 0,0663897 ! regulation of blood pressure GO:0008217 119 78 0,000 0,06464711 0,06719562 ! muscle cell differentiation GO:0042692 117 78 0,000 0,06464711 0,0671662 ! negative regulation of growth GO:0045926 140 78 0,000 0,06464711 0,0671368 ! amine transport GO:0015837 115 78 0,000 0,06464711 0,06710743 ! antigen processing and presentation GO:0019882 114 78 0,000 0,06464711 0,06707809 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,06544979 0,06788127 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,06625181 0,06868307 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,06625181 0,06865308 ! regulation of DNA binding GO:0051101 130 80 0,000 0,06625181 0,06862311 ! eye development GO:0001654 130 80 0,000 0,06625181 0,06859317 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,06625181 0,06856326 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,06625181 0,06853337 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,06625181 0,06850351 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,06625181 0,06847367 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,06625181 0,06844386 ! blood coagulation GO:0007596 129 81 0,000 0,06705319 0,06924161 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,06705319 0,06921149 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,06705319 0,0691814 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,06705319 0,06915134 ! response to hypoxia GO:0001666 155 81 0,000 0,06705319 0,0691213 ! regulation of protein transport GO:0051223 123 81 0,000 0,06705319 0,06909128 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,06785392 0,06988601 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,06785392 0,06985569 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,06785392 0,0698254 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,06785392 0,06979513 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,06865401 0,07058751 ! response to oxygen levels GO:0070482 160 83 0,000 0,06865401 0,07055694 ! regulation of lyase activity GO:0051339 147 83 0,000 0,06865401 0,07052639 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,06865401 0,07049587 ! positive regulation of lymphocyte activation GO:0051251 134 83 0,000 0,06865401 0,07046538 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,06945345 0,07125509 ! digestion GO:0007586 111 84 0,000 0,06945345 0,0712243 ! regulation of neurological system process GO:0031644 133 84 0,000 0,06945345 0,07119353 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,06945345 0,07116279 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,07025224 0,07195018 ! T cell activation GO:0042110 154 85 0,000 0,07025224 0,07191914 ! sex differentiation GO:0007548 126 85 0,000 0,07025224 0,07188813 ! protein import into nucleus GO:0006606 145 85 0,000 0,07025224 0,07185714 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,07025224 0,07182618 ! alcohol catabolic process GO:0046164 119 86 0,000 0,07105039 0,07261093 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,07105039 0,07257967 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,07184789 0,07336276 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,07184789 0,0733312 ! regulation of defense response GO:0031347 135 87 0,000 0,07184789 0,07329967 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,07184789 0,07326818 ! tRNA metabolic process GO:0006399 110 87 0,000 0,07184789 0,0732367 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,07184789 0,07320526 ! gland development GO:0048732 170 87 0,000 0,07184789 0,07317384 ! vitamin metabolic process GO:0006766 117 87 0,000 0,07184789 0,07314245 ! forebrain development GO:0030900 151 87 0,000 0,07184789 0,07311108 ! regulation of membrane potential GO:0042391 144 88 0,000 0,07264475 0,07389026 ! nucleosome assembly GO:0006334 113 89 0,000 0,07344096 0,07466812 GO:0031497|chromatin assembly, ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,07423653 0,07544466 ! microtubule cytoskeleton organization GO:0000226 133 90 0,000 0,07423653 0,07541237 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,07423653 0,0753801 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,07423653 0,07534786 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,07423653 0,07531564 ! nuclear import GO:0051170 153 90 0,000 0,07423653 0,07528346 ! regulation of protein localization GO:0032880 141 90 0,000 0,07423653 0,0752513 ! positive regulation of cell activation GO:0050867 146 90 0,000 0,07423653 0,07521917 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 123 91 0,000 0,07503146 0,07599217 ! protein localization in nucleus GO:0034504 161 92 0,000 0,07582575 0,07676386 ! sterol metabolic process GO:0016125 136 92 0,000 0,07582575 0,07673113 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,07661939 0,0775012 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cell cycle arrest GO:0007050 171 93 0,000 0,07661939 0,07746818 ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,07661939 0,07743518 ! rRNA processing GO:0006364 124 93 0,000 0,07661939 0,07740222 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,07661939 0,07736928 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,07661939 0,07733637 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,07661939 0,07730349 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,07661939 0,07727064 ! leukocyte differentiation GO:0002521 165 94 0,000 0,07741239 0,07803721 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,07741239 0,07800408 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,07741239 0,07797097 ! rRNA metabolic process GO:0016072 125 94 0,000 0,07741239 0,07793789 ! hormone metabolic process GO:0042445 135 94 0,000 0,07741239 0,07790484 ! protein processing GO:0016485 127 94 0,000 0,07741239 0,07787181 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,07820475 0,07863554 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,07820475 0,07860223 ! ATP metabolic process GO:0046034 150 96 0,000 0,07899647 0,07936436 ! nucleosome organization GO:0034728 126 96 0,000 0,07899647 0,07933078 ! female pregnancy GO:0007565 148 96 0,000 0,07899647 0,07929722 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,07978755 0,08005745 ! reproductive developmental process GO:0003006 149 97 0,000 0,07978755 0,08002361 ! response to virus GO:0009615 141 98 0,000 0,08057799 0,08078225 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,08057799 0,08074813 ! regulation of T cell activation GO:0050863 155 98 0,000 0,08057799 0,08071405 ! regulation of binding GO:0051098 164 99 0,000 0,08136779 0,08147079 ! cell fate commitment GO:0045165 165 99 0,000 0,08136779 0,08143643 ! positive regulation of immune response GO:0050778 143 99 0,000 0,08136779 0,0814021 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,08215696 0,08215696