pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/333-4-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! NLS-bearing substrate import into nucleus GO:0006607 40 18 2,000 2,754E-06 6,536E-03 ! regulation of DNA recombination GO:0000018 43 22 2,000 5,176E-06 6,141E-03 ! protein import into nucleus GO:0006606 145 85 3,000 8,953E-06 7,082E-03 ! interphase of mitotic cell cycle GO:0051329 166 87 3,000 9,821E-06 5,826E-03 ! interphase GO:0051325 169 89 3,000 1,075E-05 5,101E-03 ! nuclear import GO:0051170 153 90 3,000 1,124E-05 4,444E-03 ! protein localization in nucleus GO:0034504 161 92 3,000 1,226E-05 4,156E-03 ! deoxyribonucleoside metabolic process GO:0009120 8 6 1,000 3,513E-05 0,01042154 ! nucleoside catabolic process GO:0009164 7 6 1,000 3,513E-05 9,264E-03 ! G2 phase GO:0051319 15 6 1,000 3,513E-05 8,337E-03 GO:0000085|G2 phase of mitotic cell cycle, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 4,914E-05 0,01060071 ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 1,000 4,914E-05 9,717E-03 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 1,000 4,914E-05 8,97E-03 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! mRNA stabilization GO:0048255 16 8 1,000 6,546E-05 0,01109472 GO:0043489|RNA stabilization, ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 1,000 8,408E-05 0,01330072 ! regulation of smooth muscle cell migration GO:0014910 22 9 1,000 8,408E-05 0,01246943 ! nucleoside metabolic process GO:0009116 74 56 2,000 8,988E-05 0,01254624 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 1,000 1,282E-04 0,0169009 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 2,000 1,468E-04 0,01833669 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 1,000 1,537E-04 0,01823524 ! mRNA polyadenylation GO:0006378 19 12 1,000 1,537E-04 0,0173669 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 2,000 1,749E-04 0,01886422 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 1,000 1,815E-04 0,01872157 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 2,000 1,981E-04 0,01958547 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 2,000 1,981E-04 0,01880206 ! regulation of mRNA stability GO:0043488 30 14 1,000 2,115E-04 0,01930285 ! mRNA 3'-end processing GO:0031124 21 14 1,000 2,115E-04 0,01858793 ! RNA polyadenylation GO:0043631 21 14 1,000 2,115E-04 0,01792408 ! positive regulation of ligase activity GO:0051351 114 76 2,000 2,232E-04 0,01826277 ! regulation of RNA stability GO:0043487 31 15 1,000 2,438E-04 0,01928411 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 2,000 2,503E-04 0,01915734 ! RNA 3'-end processing GO:0031123 23 16 1,000 2,784E-04 0,02064148 ! regulation of ligase activity GO:0051340 129 82 2,000 2,794E-04 0,02009029 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 2,000 3,106E-04 0,02167881 GO:0010498|proteasomal protein catabolic process, ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 1,000 3,542E-04 0,02401536 GO:0019692|deoxyribose phosphate metabolic process, ! cellular response to unfolded protein GO:0034620 24 18 1,000 3,542E-04 0,02334827 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of DNA metabolic process GO:0051052 152 90 2,000 3,675E-04 0,02357019 ! D-ribose metabolic process GO:0006014 27 20 1,000 4,39E-04 0,02741524 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 1,000 4,39E-04 0,02671228 ! negative regulation of translation GO:0017148 28 20 1,000 4,39E-04 0,02604448 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 1,000 4,848E-04 0,02805664 ! purine ribonucleoside metabolic process GO:0046128 30 21 1,000 4,848E-04 0,02738862 GO:0042278|purine nucleoside metabolic process, ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 1,000 4,848E-04 0,02675168 ! deoxyribonucleotide metabolic process GO:0009262 29 22 1,000 5,327E-04 0,02873014 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 1,000 5,327E-04 0,02809169 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 1,000 5,829E-04 0,03006903 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 1,000 5,829E-04 0,02942926 ! DNA modification GO:0006304 33 23 1,000 5,829E-04 0,02881615 ! pentose metabolic process GO:0019321 33 24 1,000 6,353E-04 0,03076437 ! protein import into nucleus, docking GO:0000059 45 24 1,000 6,353E-04 0,03014909 ! response to endoplasmic reticulum stress GO:0034976 32 24 1,000 6,353E-04 0,02955793 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 1,000 6,353E-04 0,02898951 ! ER-nuclear signaling pathway GO:0006984 33 26 1,000 7,466E-04 0,03342715 ! spermatid development GO:0007286 40 26 1,000 7,466E-04 0,03280812 ! fat cell differentiation GO:0045444 41 27 1,000 8,055E-04 0,03475479 ! regulation of alpha-beta T cell activation GO:0046634 46 27 1,000 8,055E-04 0,03413417 ! spermatid differentiation GO:0048515 45 29 1,000 9,299E-04 0,03871492 ! positive regulation of T cell differentiation GO:0045582 45 31 1,000 1,063E-03 0,04349199 ! positive regulation of T cell proliferation GO:0042102 56 32 1,000 1,133E-03 0,04556093 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 1,000 1,205E-03 0,04764576 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 1,000 1,355E-03 0,05270916 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 1,000 1,355E-03 0,05185901 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 1,000 1,514E-03 0,05701514 ! ribonucleoside metabolic process GO:0009119 51 38 1,000 1,596E-03 0,05918486 ! positive regulation of leukocyte proliferation GO:0070665 64 39 1,000 1,681E-03 0,06136476 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to calcium ion GO:0051592 65 43 1,000 2,04E-03 0,07336244 ! regulation of T cell proliferation GO:0042129 72 43 1,000 2,04E-03 0,07226748 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 1,000 2,136E-03 0,07452315 ! positive regulation of cell cycle GO:0045787 83 45 1,000 2,233E-03 0,07678461 ! regulation of T cell differentiation GO:0045580 68 45 1,000 2,233E-03 0,07568769 ! response to UV GO:0009411 79 47 1,000 2,433E-03 0,08132305 ! negative regulation of cell migration GO:0030336 105 50 1,000 2,749E-03 0,09061239 ! heterocycle catabolic process GO:0046700 74 50 1,000 2,749E-03 0,08937112 ! regulation of mast cell proliferation GO:0070666 80 50 1,000 2,749E-03 0,08816341 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 1,000 3,084E-03 0,09756857 ! regulation of lymphocyte differentiation GO:0045619 84 53 1,000 3,084E-03 0,09628477 ! regulation of leukocyte proliferation GO:0070663 88 53 1,000 3,084E-03 0,09503432 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! germ cell development GO:0007281 82 54 1,000 3,199E-03 0,09732993 ! negative regulation of cell motion GO:0051271 118 58 1,000 3,681E-03 0,11057708 ! extracellular matrix organization GO:0030198 117 67 1,000 4,881E-03 0,14478904 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 5,024E-03 0,14719245 ! positive regulation of T cell activation GO:0050870 117 72 1,000 5,616E-03 0,16251141 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 1,000 5,923E-03 0,16933377 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 6,079E-03 0,17173585 ! response to metal ion GO:0010038 114 76 1,000 6,237E-03 0,17413393 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 6,398E-03 0,17652799 GO:0045937|positive regulation of phosphate metabolic process, ! response to unfolded protein GO:0006986 113 80 1,000 6,889E-03 0,18790853 ! response to inorganic substance GO:0010035 127 81 1,000 7,057E-03 0,19029238 ! nitrogen compound catabolic process GO:0044270 125 81 1,000 7,057E-03 0,18815426 ! positive regulation of protein modification process GO:0031401 126 83 1,000 7,397E-03 0,19504705 ! positive regulation of lymphocyte activation GO:0051251 134 83 1,000 7,397E-03 0,19290368 ! response to protein stimulus GO:0051789 127 85 1,000 7,746E-03 0,19978431 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 7,77E-03 0,19826453 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 7,77E-03 0,19615533 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 7,77E-03 0,19409054 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 7,77E-03 0,19206876 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 7,77E-03 0,19008867 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 7,77E-03 0,18814899 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,77E-03 0,1862485 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 7,77E-03 0,18438601 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 7,77E-03 0,18256041 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 7,77E-03 0,1807706 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 7,77E-03 0,17901555 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 7,77E-03 0,17729424 ! response to oxygen radical GO:0000305 11 5 0,000 7,77E-03 0,17560573 ! negative regulation of bone resorption GO:0045779 11 5 0,000 7,77E-03 0,17394907 ! myoblast cell fate commitment GO:0048625 8 5 0,000 7,77E-03 0,17232338 ! nucleotide-sugar transport GO:0015780 8 5 0,000 7,77E-03 0,17072779 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 7,77E-03 0,16916148 ! regulation of interferon-beta production GO:0032648 5 5 0,000 7,77E-03 0,16762365 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 7,77E-03 0,16611353 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 7,77E-03 0,16463037 ! female meiosis GO:0007143 8 5 0,000 7,77E-03 0,16317346 ! nose development GO:0043584 10 5 0,000 7,77E-03 0,16174212 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 7,77E-03 0,16033566 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 7,77E-03 0,15895346 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 7,77E-03 0,15759488 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 7,77E-03 0,15625933 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 7,77E-03 0,15494623 ! cobalt ion transport GO:0006824 9 5 0,000 7,77E-03 0,15365501 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 7,77E-03 0,15238513 ! SMAD protein complex assembly GO:0007183 10 5 0,000 7,77E-03 0,15113608 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 7,77E-03 0,14990733 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 7,77E-03 0,1486984 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 7,77E-03 0,14750881 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 7,77E-03 0,14633811 ! adaptation of signaling pathway GO:0022401 9 5 0,000 7,77E-03 0,14518584 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 7,77E-03 0,14405157 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,77E-03 0,14293489 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 7,77E-03 0,14183539 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,77E-03 0,14075268 ! negative regulation of histone modification GO:0031057 7 5 0,000 7,77E-03 0,13968637 ! malate metabolic process GO:0006108 8 5 0,000 7,77E-03 0,1386361 ! positive regulation of histone modification GO:0031058 6 5 0,000 7,77E-03 0,1376015 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 7,77E-03 0,13658223 ! clathrin coat assembly GO:0048268 11 5 0,000 7,77E-03 0,13557795 ! Notch receptor processing GO:0007220 8 5 0,000 7,77E-03 0,13458833 ! phototransduction, visible light GO:0007603 7 5 0,000 7,77E-03 0,13361305 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,77E-03 0,13265181 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 7,77E-03 0,13170429 ! mating behavior GO:0007617 6 5 0,000 7,77E-03 0,13077022 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 7,77E-03 0,1298493 ! copulation GO:0007620 8 5 0,000 7,77E-03 0,12894127 ! protein maturation by protein folding GO:0022417 13 5 0,000 7,77E-03 0,12804584 ! embryonic hemopoiesis GO:0035162 13 5 0,000 7,77E-03 0,12716277 ! regulation of potassium ion transport GO:0043266 9 5 0,000 7,77E-03 0,12629179 ! apoptotic cell clearance GO:0043277 14 5 0,000 7,77E-03 0,12543266 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 7,77E-03 0,12458514 ! lipoprotein particle clearance GO:0034381 9 5 0,000 7,77E-03 0,123749 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 7,77E-03 0,12292401 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 7,77E-03 0,12210994 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 7,77E-03 0,12130659 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 7,77E-03 0,12051373 ! response to axon injury GO:0048678 8 5 0,000 7,77E-03 0,11973118 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,77E-03 0,11895872 ! response to protozoan GO:0001562 10 5 0,000 7,77E-03 0,11819616 ! negative regulation of heart contraction GO:0045822 12 5 0,000 7,77E-03 0,11744332 ! lymph vessel development GO:0001945 8 5 0,000 7,77E-03 0,11670001 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 7,77E-03 0,11596605 ! endochondral ossification GO:0001958 13 5 0,000 7,77E-03 0,11524126 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 7,77E-03 0,11452547 ! single strand break repair GO:0000012 5 5 0,000 7,77E-03 0,11381853 ! parathyroid gland development GO:0060017 8 5 0,000 7,77E-03 0,11312025 ! anagen GO:0042640 7 5 0,000 7,77E-03 0,1124305 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 7,77E-03 0,1117491 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 7,77E-03 0,11107591 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 7,77E-03 0,11041079 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 7,77E-03 0,10975358 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 7,77E-03 0,10910415 ! smooth muscle tissue development GO:0048745 14 5 0,000 7,77E-03 0,10846236 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,77E-03 0,10782808 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 7,77E-03 0,10720117 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 7,77E-03 0,10658151 ! cardiac muscle fiber development GO:0048739 8 5 0,000 7,77E-03 0,10596897 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,77E-03 0,10536344 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 7,77E-03 0,10476478 ! neutrophil mediated immunity GO:0002446 6 5 0,000 7,77E-03 0,10417289 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 7,77E-03 0,10358765 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 7,77E-03 0,10300895 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 7,77E-03 0,10243667 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 7,77E-03 0,10187073 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 7,77E-03 0,101311 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 7,77E-03 0,10075738 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 7,77E-03 0,10020979 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 7,77E-03 0,09966812 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 7,77E-03 0,09913226 ! tyrosine catabolic process GO:0006572 7 5 0,000 7,77E-03 0,09860215 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 7,77E-03 0,09807767 ! proline biosynthetic process GO:0006561 6 5 0,000 7,77E-03 0,09755874 ! L-serine biosynthetic process GO:0006564 6 5 0,000 7,77E-03 0,09704527 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,77E-03 0,09653718 ! polyol catabolic process GO:0046174 7 5 0,000 7,77E-03 0,09603438 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 7,77E-03 0,09553679 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,77E-03 0,09504434 ! sister chromatid cohesion GO:0007062 10 5 0,000 7,77E-03 0,09455693 ! response to ATP GO:0033198 6 5 0,000 7,77E-03 0,0940745 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 7,77E-03 0,09359696 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 7,77E-03 0,09312425 ! neutrophil activation GO:0042119 6 5 0,000 7,77E-03 0,09265629 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 7,77E-03 0,09219301 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 7,77E-03 0,09173433 ! response to food GO:0032094 5 5 0,000 7,77E-03 0,0912802 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 7,77E-03 0,09083055 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 7,77E-03 0,0903853 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 7,77E-03 0,0899444 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,77E-03 0,08950777 ! paraxial mesoderm development GO:0048339 9 5 0,000 7,77E-03 0,08907537 ! forebrain neuron development GO:0021884 7 5 0,000 7,77E-03 0,08864712 ! melanosome organization GO:0032438 7 5 0,000 7,77E-03 0,08822297 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 7,77E-03 0,08780286 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 7,77E-03 0,08738674 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 7,77E-03 0,08697453 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 7,77E-03 0,0865662 ! mesodermal cell fate determination GO:0007500 7 5 0,000 7,77E-03 0,08616169 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,77E-03 0,08576094 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 7,77E-03 0,08536389 ! nucleoside salvage GO:0043174 7 5 0,000 7,77E-03 0,08497051 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 7,77E-03 0,08458074 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 7,77E-03 0,08419453 ! negative regulation of platelet activation GO:0010544 8 5 0,000 7,77E-03 0,08381182 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 7,77E-03 0,08343258 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,77E-03 0,08305676 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 7,77E-03 0,08268431 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 7,77E-03 0,08231518 ! early endosome to late endosome transport GO:0045022 11 5 0,000 7,77E-03 0,08194934 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 7,77E-03 0,08158673 ! depyrimidination GO:0045008 8 5 0,000 7,77E-03 0,08122732 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,77E-03 0,08087106 ! 5S class rRNA transcription GO:0042791 8 5 0,000 7,77E-03 0,08051791 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 7,77E-03 0,08016783 ! neuronal ion channel clustering GO:0045161 8 5 0,000 7,77E-03 0,07982078 ! sodium ion homeostasis GO:0055078 6 5 0,000 7,77E-03 0,07947673 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 7,77E-03 0,07913563 ! monocyte differentiation GO:0030224 7 5 0,000 7,77E-03 0,07879744 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 7,77E-03 0,07846213 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 7,77E-03 0,07812967 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 7,77E-03 0,07780001 ! response to UV-C GO:0010225 7 5 0,000 7,77E-03 0,07747311 ! protein targeting to vacuole GO:0006623 6 5 0,000 7,77E-03 0,07714896 ! activated T cell proliferation GO:0050798 7 5 0,000 7,77E-03 0,07682751 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 7,77E-03 0,07650872 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 7,77E-03 0,07619257 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 7,77E-03 0,07587902 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 7,77E-03 0,07556804 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 7,77E-03 0,0752596 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 7,77E-03 0,07495366 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 7,77E-03 0,07465021 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 7,77E-03 0,0743492 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 7,77E-03 0,07405061 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 7,77E-03 0,07375441 ! response to cadmium ion GO:0046686 8 5 0,000 7,77E-03 0,07346056 ! melanosome transport GO:0032402 8 5 0,000 7,77E-03 0,07316905 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 7,77E-03 0,07287985 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 7,77E-03 0,07259292 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 7,77E-03 0,07230824 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 7,77E-03 0,07202579 ! positive T cell selection GO:0043368 10 5 0,000 7,77E-03 0,07174553 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 7,77E-03 0,07146745 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 7,77E-03 0,07119151 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 7,77E-03 0,0709177 ! ribosomal subunit assembly GO:0042257 5 5 0,000 7,77E-03 0,07064598 ! base conversion or substitution editing GO:0016553 6 5 0,000 7,77E-03 0,07037634 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 7,77E-03 0,07010875 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 7,77E-03 0,06984319 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 7,77E-03 0,06957963 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 7,77E-03 0,06931805 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 7,77E-03 0,06905843 ! histone demethylation GO:0016577 10 5 0,000 7,77E-03 0,06880075 ! mitotic recombination GO:0006312 10 5 0,000 7,77E-03 0,06854499 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 7,77E-03 0,06829112 ! regulation of sterol transport GO:0032371 7 5 0,000 7,77E-03 0,06803912 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 7,77E-03 0,06778898 ! sympathetic nervous system development GO:0048485 13 5 0,000 7,77E-03 0,06754066 ! enteric nervous system development GO:0048484 9 5 0,000 7,77E-03 0,06729417 ! oxygen homeostasis GO:0032364 8 5 0,000 7,77E-03 0,06704946 ! establishment of planar polarity GO:0001736 7 5 0,000 7,77E-03 0,06680653 ! lymphocyte costimulation GO:0031294 12 5 0,000 7,77E-03 0,06656535 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 7,77E-03 0,0663259 ! transcription termination GO:0006353 8 5 0,000 7,77E-03 0,06608818 ! plasminogen activation GO:0031639 5 5 0,000 7,77E-03 0,06585215 ! B cell homeostasis GO:0001782 12 5 0,000 7,77E-03 0,0656178 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 7,77E-03 0,06538511 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 7,77E-03 0,06515407 ! regulation of hair follicle development GO:0051797 9 5 0,000 7,77E-03 0,06492465 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 7,77E-03 0,06469685 ! apical protein localization GO:0045176 8 5 0,000 7,77E-03 0,06447063 ! definitive hemopoiesis GO:0060216 5 5 0,000 7,77E-03 0,064246 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 7,77E-03 0,06402292 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 7,77E-03 0,06380139 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 7,77E-03 0,06358138 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 7,77E-03 0,06336289 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 7,77E-03 0,06314589 ! regulation of centrosome duplication GO:0010824 6 5 0,000 7,77E-03 0,06293038 ! disaccharide metabolic process GO:0005984 9 5 0,000 7,77E-03 0,06271633 ! galactolipid metabolic process GO:0019374 8 5 0,000 7,77E-03 0,06250373 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 7,77E-03 0,06229257 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 7,77E-03 0,06208283 ! determination of adult lifespan GO:0008340 8 5 0,000 7,77E-03 0,0618745 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 7,77E-03 0,06166756 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 7,77E-03 0,061462 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 7,77E-03 0,06125781 ! T cell activation during immune response GO:0002286 9 5 0,000 7,77E-03 0,06105497 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 7,77E-03 0,06085347 ! negative regulation of lipase activity GO:0060192 7 5 0,000 7,77E-03 0,06065329 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 7,77E-03 0,06045443 ! neural plate development GO:0001840 7 5 0,000 7,77E-03 0,06025687 ! regulation of sensory perception GO:0051931 6 5 0,000 7,77E-03 0,06006059 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 7,77E-03 0,05986559 ! regulation of histone acetylation GO:0035065 7 5 0,000 7,77E-03 0,05967185 ! sensory cilium assembly GO:0035058 6 5 0,000 7,77E-03 0,05947936 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 7,77E-03 0,05928811 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 7,77E-03 0,05909808 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,77E-03 0,05890927 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 7,77E-03 0,05872166 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 7,77E-03 0,05853524 ! receptor biosynthetic process GO:0032800 6 5 0,000 7,77E-03 0,05835 ! penetration of zona pellucida GO:0007341 9 5 0,000 7,77E-03 0,05816593 ! drug metabolic process GO:0017144 5 5 0,000 7,77E-03 0,05798302 ! protein amino acid prenylation GO:0018346 9 5 0,000 7,77E-03 0,05780126 ! organ regeneration GO:0031100 7 5 0,000 7,77E-03 0,05762063 ! carnitine metabolic process GO:0009437 5 5 0,000 7,77E-03 0,05744113 GO:0006577|betaine metabolic process, ! forebrain development GO:0030900 151 87 1,000 8,101E-03 0,05969996 ! ossification GO:0001503 150 89 1,000 8,463E-03 0,06217899 GO:0060348|bone development, ! transcription initiation GO:0006352 128 90 1,000 8,647E-03 0,06333471 ! positive regulation of cell activation GO:0050867 146 90 1,000 8,647E-03 0,06313983 GO:0002696|positive regulation of leukocyte activation, ! tRNA transcription GO:0009304 11 6 0,000 9,317E-03 0,067821 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 9,317E-03 0,0676136 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,317E-03 0,06740746 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 9,317E-03 0,06720257 ! regulation of helicase activity GO:0051095 11 6 0,000 9,317E-03 0,06699893 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 9,317E-03 0,06679652 ! sleep GO:0030431 13 6 0,000 9,317E-03 0,06659532 ! positive regulation of axon extension GO:0045773 10 6 0,000 9,317E-03 0,06639534 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 9,317E-03 0,06619655 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 9,317E-03 0,06599895 ! forebrain regionalization GO:0021871 7 6 0,000 9,317E-03 0,06580252 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 9,317E-03 0,06560726 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 9,317E-03 0,06541316 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 9,317E-03 0,0652202 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 9,317E-03 0,06502837 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 9,317E-03 0,06483767 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 9,317E-03 0,06464809 ! neuron adhesion GO:0007158 9 6 0,000 9,317E-03 0,06445961 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 9,317E-03 0,06427223 ! signal peptide processing GO:0006465 8 6 0,000 9,317E-03 0,06408593 ! embryonic camera-type eye development GO:0031076 11 6 0,000 9,317E-03 0,06390071 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 9,317E-03 0,06371656 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 9,317E-03 0,06353347 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 9,317E-03 0,06335142 ! fibril organization GO:0043206 13 6 0,000 9,317E-03 0,06317042 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 9,317E-03 0,06299045 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 9,317E-03 0,0628115 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 9,317E-03 0,06263356 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 9,317E-03 0,06245663 ! protein refolding GO:0042026 13 6 0,000 9,317E-03 0,0622807 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 9,317E-03 0,06210575 ! rhythmic behavior GO:0007622 14 6 0,000 9,317E-03 0,06193178 ! glial cell fate commitment GO:0021781 17 6 0,000 9,317E-03 0,06175879 ! erythrocyte maturation GO:0043249 7 6 0,000 9,317E-03 0,06158676 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 9,317E-03 0,06141569 ! protein amino acid dealkylation GO:0008214 12 6 0,000 9,317E-03 0,06124556 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 9,317E-03 0,06107637 ! regulation of odontogenesis GO:0042481 8 6 0,000 9,317E-03 0,06090812 ! mechanosensory behavior GO:0007638 8 6 0,000 9,317E-03 0,06074079 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 9,317E-03 0,06057438 ! negative regulation of endocytosis GO:0045806 8 6 0,000 9,317E-03 0,06040887 ! response to interferon-gamma GO:0034341 12 6 0,000 9,317E-03 0,06024427 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 9,317E-03 0,06008056 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 9,317E-03 0,05991774 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 9,317E-03 0,0597558 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 9,317E-03 0,05959474 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 9,317E-03 0,05943454 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 9,317E-03 0,05927519 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 9,317E-03 0,0591167 ! cGMP-mediated signaling GO:0019934 11 6 0,000 9,317E-03 0,05895906 ! activation of MAPKKK activity GO:0000185 11 6 0,000 9,317E-03 0,05880225 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 9,317E-03 0,05864628 ! protein lipoylation GO:0009249 10 6 0,000 9,317E-03 0,05849113 ! pigment granule organization GO:0048753 11 6 0,000 9,317E-03 0,0583368 ! drug transport GO:0015893 6 6 0,000 9,317E-03 0,05818328 ! transepithelial chloride transport GO:0030321 10 6 0,000 9,317E-03 0,05803057 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 9,317E-03 0,05787866 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 9,317E-03 0,05772754 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 9,317E-03 0,05757721 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 9,317E-03 0,05742765 ! glutamate catabolic process GO:0006538 11 6 0,000 9,317E-03 0,05727888 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 9,317E-03 0,05713087 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 9,317E-03 0,05698363 ! adenohypophysis development GO:0021984 10 6 0,000 9,317E-03 0,05683714 ! response to pH GO:0009268 10 6 0,000 9,317E-03 0,0566914 ! hyperosmotic response GO:0006972 9 6 0,000 9,317E-03 0,05654641 ! microtubule nucleation GO:0007020 10 6 0,000 9,317E-03 0,05640216 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 9,317E-03 0,05625864 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 9,317E-03 0,05611586 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 9,317E-03 0,05597379 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 9,317E-03 0,05583244 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 9,317E-03 0,05569181 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 9,317E-03 0,05555188 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 9,317E-03 0,05541265 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 9,317E-03 0,05527412 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 9,317E-03 0,05513628 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 9,317E-03 0,05499912 ! purine salvage GO:0043101 9 6 0,000 9,317E-03 0,05486265 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,317E-03 0,05472685 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 9,317E-03 0,05459172 ! nucleoside transport GO:0015858 7 6 0,000 9,317E-03 0,05445726 ! organic alcohol transport GO:0015850 9 6 0,000 9,317E-03 0,05432346 ! T cell mediated immunity GO:0002456 12 6 0,000 9,317E-03 0,05419031 ! folic acid transport GO:0015884 11 6 0,000 9,317E-03 0,05405782 ! male sex determination GO:0030238 11 6 0,000 9,317E-03 0,05392597 ! carnitine transport GO:0015879 8 6 0,000 9,317E-03 0,05379476 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 9,317E-03 0,05366419 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,317E-03 0,05353425 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 9,317E-03 0,05340494 ! positive regulation of exocytosis GO:0045921 9 6 0,000 9,317E-03 0,05327626 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 9,317E-03 0,05314819 ! parturition GO:0007567 13 6 0,000 9,317E-03 0,05302074 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 9,317E-03 0,05289389 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 9,317E-03 0,05276765 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 9,317E-03 0,05264202 ! regulation of centrosome cycle GO:0046605 8 6 0,000 9,317E-03 0,05251698 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 9,317E-03 0,05239253 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 9,317E-03 0,05226867 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 9,317E-03 0,05214539 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 9,317E-03 0,0520227 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 9,317E-03 0,05190058 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 9,317E-03 0,05177903 ! neural nucleus development GO:0048857 12 6 0,000 9,317E-03 0,05165805 ! forebrain morphogenesis GO:0048853 14 6 0,000 9,317E-03 0,05153764 ! hyaluronan metabolic process GO:0030212 7 6 0,000 9,317E-03 0,05141778 ! purine base biosynthetic process GO:0009113 14 6 0,000 9,317E-03 0,05129849 ! interaction with symbiont GO:0051702 9 6 0,000 9,317E-03 0,05117974 ! regulation of dendrite development GO:0050773 13 6 0,000 9,317E-03 0,05106154 ! anterograde axon cargo transport GO:0008089 9 6 0,000 9,317E-03 0,05094389 ! positive regulation of organ growth GO:0046622 7 6 0,000 9,317E-03 0,05082677 ! eating behavior GO:0042755 6 6 0,000 9,317E-03 0,0507102 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 9,317E-03 0,05059416 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 9,317E-03 0,05047865 ! response to copper ion GO:0046688 9 6 0,000 9,317E-03 0,05036366 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 9,317E-03 0,0502492 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 9,317E-03 0,05013525 ! establishment of melanosome localization GO:0032401 9 6 0,000 9,317E-03 0,05002183 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,317E-03 0,04990891 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 9,317E-03 0,0497965 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 9,317E-03 0,0496846 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,317E-03 0,0495732 ! hair follicle maturation GO:0048820 8 6 0,000 9,317E-03 0,0494623 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 9,317E-03 0,04935189 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 9,317E-03 0,04924198 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 9,317E-03 0,04913255 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 9,317E-03 0,04902361 ! rhombomere development GO:0021546 6 6 0,000 9,317E-03 0,04891515 ! positive regulation of Rho GTPase activity GO:0032321 12 6 0,000 9,317E-03 0,04880717 ! establishment of chromosome localization GO:0051303 10 6 0,000 9,317E-03 0,04869966 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 9,317E-03 0,04859263 ! muscle cell proliferation GO:0033002 9 6 0,000 9,317E-03 0,04848607 ! membrane to membrane docking GO:0022614 12 6 0,000 9,317E-03 0,04837997 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 9,317E-03 0,04827434 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 9,317E-03 0,04816917 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 9,317E-03 0,04806445 ! receptor internalization GO:0031623 9 6 0,000 9,317E-03 0,04796019 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 9,317E-03 0,04785638 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 9,317E-03 0,04775302 ! coenzyme A metabolic process GO:0015936 9 6 0,000 9,317E-03 0,0476501 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 9,317E-03 0,04754763 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 9,317E-03 0,04744559 ! peptidyl-histidine modification GO:0018202 10 6 0,000 9,317E-03 0,047344 ! axonal fasciculation GO:0007413 10 6 0,000 9,317E-03 0,04724284 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 9,317E-03 0,0471421 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 9,317E-03 0,0470418 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 9,317E-03 0,04694193 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 9,317E-03 0,04684247 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,317E-03 0,04674344 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 9,317E-03 0,04664483 ! progesterone metabolic process GO:0042448 8 6 0,000 9,317E-03 0,04654663 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 9,317E-03 0,04644884 ! glycolipid catabolic process GO:0019377 14 6 0,000 9,317E-03 0,04635146 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 9,317E-03 0,04625449 ! negative regulation of axon extension GO:0030517 13 6 0,000 9,317E-03 0,04615793 ! removal of superoxide radicals GO:0019430 10 6 0,000 9,317E-03 0,04606176 ! triglyceride catabolic process GO:0019433 8 6 0,000 9,317E-03 0,045966 ! protein modification by small protein removal GO:0070646 10 6 0,000 9,317E-03 0,04587064 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 9,317E-03 0,04577567 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 9,317E-03 0,04568109 ! glial cell migration GO:0008347 11 6 0,000 9,317E-03 0,0455869 ! blastocyst growth GO:0001832 17 6 0,000 9,317E-03 0,0454931 ! pigment granule transport GO:0051904 12 6 0,000 9,317E-03 0,04539969 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 9,317E-03 0,04530665 ! cerebellar cortex formation GO:0021697 9 6 0,000 9,317E-03 0,045214 ! catecholamine transport GO:0051937 7 6 0,000 9,317E-03 0,04512173 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 9,317E-03 0,04502983 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 9,317E-03 0,04493831 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,317E-03 0,04484715 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 9,317E-03 0,04475637 ! spindle assembly GO:0051225 6 6 0,000 9,317E-03 0,04466595 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 9,317E-03 0,0445759 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 9,317E-03 0,04448621 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 9,317E-03 0,04439688 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 9,317E-03 0,04430791 ! NAD biosynthetic process GO:0009435 9 6 0,000 9,317E-03 0,04421929 ! positive regulation of coagulation GO:0050820 11 6 0,000 9,317E-03 0,04413103 ! cellular anion homeostasis GO:0030002 9 6 0,000 9,317E-03 0,04404312 GO:0055081|anion homeostasis, ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 1,000 9,594E-03 0,04526285 ! regulation of T cell activation GO:0050863 155 98 1,000 0,0101836 0,0479478 ! behavioral response to cocaine GO:0048148 13 7 0,000 0,01086184 0,05103991 ! autophagic vacuole formation GO:0000045 12 7 0,000 0,01086184 0,05093904 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01086184 0,05083857 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 0,01086184 0,05073849 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 0,01086184 0,05063881 ! prostate gland development GO:0030850 11 7 0,000 0,01086184 0,05053952 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01086184 0,05044061 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 0,01086184 0,0503421 ! synaptonemal complex assembly GO:0007130 11 7 0,000 0,01086184 0,05024396 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 0,01086184 0,05014621 ! male meiosis GO:0007140 10 7 0,000 0,01086184 0,05004884 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01086184 0,04995185 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 0,01086184 0,04985523 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01086184 0,04975898 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01086184 0,04966311 ! oligopeptide transport GO:0006857 11 7 0,000 0,01086184 0,0495676 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01086184 0,04947246 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 0,01086184 0,04937769 ! establishment of tissue polarity GO:0007164 10 7 0,000 0,01086184 0,04928328 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 0,01086184 0,04918922 ! RNA methylation GO:0001510 11 7 0,000 0,01086184 0,04909553 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 0,01086184 0,04900219 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 0,01086184 0,04890921 ! pericardium development GO:0060039 9 7 0,000 0,01086184 0,04881658 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01086184 0,0487243 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01086184 0,04863237 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01086184 0,04854078 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01086184 0,04844954 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01086184 0,04835864 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01086184 0,04826808 ! opsonization GO:0008228 9 7 0,000 0,01086184 0,04817786 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 0,01086184 0,04808797 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01086184 0,04799842 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 0,01086184 0,04790921 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 0,01086184 0,04782032 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01086184 0,04773177 ! chemosensory behavior GO:0007635 9 7 0,000 0,01086184 0,04764354 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01086184 0,04755563 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01086184 0,04746805 ! leukocyte degranulation GO:0043299 11 7 0,000 0,01086184 0,0473808 ! positive regulation of glycolysis GO:0045821 13 7 0,000 0,01086184 0,04729386 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 0,01086184 0,04720724 ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01086184 0,04712094 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01086184 0,04703495 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 0,01086184 0,04694928 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01086184 0,04686392 ! spinal cord patterning GO:0021511 9 7 0,000 0,01086184 0,04677886 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01086184 0,04669412 ! thymic T cell selection GO:0045061 15 7 0,000 0,01086184 0,04660968 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 0,01086184 0,04652555 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01086184 0,04644172 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01086184 0,04635819 ! ovulation GO:0030728 8 7 0,000 0,01086184 0,04627496 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 0,01086184 0,04619203 ! histidine metabolic process GO:0006547 7 7 0,000 0,01086184 0,0461094 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 0,01086184 0,04602706 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01086184 0,04594502 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! ER overload response GO:0006983 8 7 0,000 0,01086184 0,04586326 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01086184 0,0457818 ! endosome organization GO:0007032 10 7 0,000 0,01086184 0,04570063 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01086184 0,04561974 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 0,01086184 0,04553914 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 0,01086184 0,04545882 ! urea metabolic process GO:0019627 9 7 0,000 0,01086184 0,04537879 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 0,01086184 0,04529904 ! vesicle fusion GO:0006906 15 7 0,000 0,01086184 0,04521957 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 0,01086184 0,04514037 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 0,01086184 0,04506146 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01086184 0,04498282 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 0,01086184 0,04490445 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 0,01086184 0,04482635 ! organ growth GO:0035265 13 7 0,000 0,01086184 0,04474853 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 0,01086184 0,04467098 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01086184 0,04459369 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 0,01086184 0,04451667 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 0,01086184 0,04443992 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 0,01086184 0,04436343 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 0,01086184 0,04428721 ! rRNA modification GO:0000154 12 7 0,000 0,01086184 0,04421124 ! negative regulation of translational initiation GO:0045947 9 7 0,000 0,01086184 0,04413554 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 0,01086184 0,04406009 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 0,01086184 0,0439849 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01086184 0,04390997 ! response to UV-B GO:0010224 11 7 0,000 0,01086184 0,0438353 ! astrocyte development GO:0014002 15 7 0,000 0,01086184 0,04376087 ! intermediate filament organization GO:0045109 12 7 0,000 0,01086184 0,0436867 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01086184 0,04361278 ! fibrinolysis GO:0042730 9 7 0,000 0,01086184 0,04353911 ! peptidyl-arginine modification GO:0018195 9 7 0,000 0,01086184 0,04346569 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 0,01086184 0,04339251 ! blastoderm segmentation GO:0007350 11 7 0,000 0,01086184 0,04331959 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01086184 0,0432469 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01086184 0,04317446 ! DNA topological change GO:0006265 10 7 0,000 0,01086184 0,04310226 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 0,01086184 0,04303031 ! melanosome localization GO:0032400 10 7 0,000 0,01086184 0,04295859 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 0,01086184 0,04288711 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 0,01086184 0,04281587 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 0,01086184 0,04274487 ! mast cell activation GO:0045576 10 7 0,000 0,01086184 0,0426741 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01086184 0,04260356 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 0,01086184 0,04253326 ! gas homeostasis GO:0033483 12 7 0,000 0,01086184 0,04246319 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 0,01086184 0,04239334 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 0,01086184 0,04232373 ! Schwann cell development GO:0014044 16 7 0,000 0,01086184 0,04225435 ! dendrite morphogenesis GO:0048813 12 7 0,000 0,01086184 0,04218519 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 0,01086184 0,04211626 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 0,01086184 0,04204756 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 0,01086184 0,04197908 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 0,01086184 0,04191082 ! neural tube patterning GO:0021532 8 7 0,000 0,01086184 0,04184278 ! histone ubiquitination GO:0016574 10 7 0,000 0,01086184 0,04177497 ! regulation of meiosis GO:0040020 12 7 0,000 0,01086184 0,04170737 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 0,01086184 0,04163999 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 0,01086184 0,04157283 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01086184 0,04150588 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 0,01086184 0,04143915 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01086184 0,04137264 ! regulation of cell division GO:0051302 9 7 0,000 0,01086184 0,04130634 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 0,01086184 0,04124025 ! neutrophil homeostasis GO:0001780 8 7 0,000 0,01086184 0,04117437 ! regulation of macrophage activation GO:0043030 12 7 0,000 0,01086184 0,0411087 ! negative regulation of nuclear division GO:0051784 18 7 0,000 0,01086184 0,04104324 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01086184 0,04097799 ! diuresis GO:0030146 11 7 0,000 0,01086184 0,04091294 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 0,01086184 0,0408481 ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01086184 0,04078347 ! thiamin metabolic process GO:0006772 8 7 0,000 0,01086184 0,04071904 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 0,01086184 0,04065482 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 0,01086184 0,04059079 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 0,01086184 0,04052697 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01086184 0,04046335 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01086184 0,04039993 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01086184 0,0403367 ! lymph node development GO:0048535 9 7 0,000 0,01086184 0,04027368 ! anterior/posterior axis specification GO:0009948 11 7 0,000 0,01086184 0,04021085 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 0,01086184 0,04014821 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 0,01086184 0,04008578 ! positive regulation of glucose import GO:0046326 7 7 0,000 0,01086184 0,04002353 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01086184 0,03996148 ! ATP catabolic process GO:0006200 10 7 0,000 0,01086184 0,03989962 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01086184 0,03983795 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 0,01086184 0,03977647 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01086184 0,03971518 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 0,01086184 0,03965408 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01086184 0,03959317 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 0,01086184 0,03953244 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01086184 0,0394719 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01086184 0,03941155 ! muscle adaptation GO:0043500 12 7 0,000 0,01086184 0,03935138 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01086184 0,03929139 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 0,01086184 0,03923159 ! retina homeostasis GO:0001895 9 7 0,000 0,01086184 0,03917197 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01086184 0,03911252 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 0,01086184 0,03905326 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 0,01086184 0,03899418 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 0,01086184 0,03893528 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01086184 0,03887655 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 0,01240418 0,04433001 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 0,01240418 0,04426335 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01240418 0,04419689 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01240418 0,04413063 ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 0,01240418 0,04406456 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 0,01240418 0,0439987 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 0,01240418 0,04393303 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 0,01240418 0,04386755 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 0,01240418 0,04380228 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01240418 0,04373719 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01240418 0,0436723 ! neutral lipid catabolic process GO:0046461 11 8 0,000 0,01240418 0,0436076 ! N-glycan processing GO:0006491 12 8 0,000 0,01240418 0,04354309 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01240418 0,04347877 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 0,01240418 0,04341464 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 0,01240418 0,04335071 ! induction of positive chemotaxis GO:0050930 16 8 0,000 0,01240418 0,04328695 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01240418 0,04322339 ! lipoprotein transport GO:0042953 14 8 0,000 0,01240418 0,04316001 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01240418 0,04309682 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01240418 0,04303381 ! keratinocyte proliferation GO:0043616 15 8 0,000 0,01240418 0,04297099 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01240418 0,04290835 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01240418 0,04284589 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 0,01240418 0,04278362 ! bile acid and bile salt transport GO:0015721 12 8 0,000 0,01240418 0,04272152 ! ganglioside metabolic process GO:0001573 16 8 0,000 0,01240418 0,04265961 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 0,01240418 0,04259787 ! reflex GO:0060004 16 8 0,000 0,01240418 0,04253631 ! positive regulation of isotype switching GO:0045830 16 8 0,000 0,01240418 0,04247493 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01240418 0,04241373 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 0,01240418 0,0423527 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01240418 0,04229185 ! glycerolipid catabolic process GO:0046503 11 8 0,000 0,01240418 0,04223117 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 0,01240418 0,04217067 ! hemoglobin metabolic process GO:0020027 12 8 0,000 0,01240418 0,04211034 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01240418 0,04205018 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 0,01240418 0,0419902 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 0,01240418 0,04193038 ! adrenal gland development GO:0030325 18 8 0,000 0,01240418 0,04187074 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 0,01240418 0,04181126 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01240418 0,04175196 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01240418 0,04169282 ! proline metabolic process GO:0006560 9 8 0,000 0,01240418 0,04163385 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01240418 0,04157504 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 0,01240418 0,0415164 ! regulation of pigmentation during development GO:0048070 18 8 0,000 0,01240418 0,04145793 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 0,01240418 0,04139962 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 0,01240418 0,04134147 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01240418 0,04128349 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01240418 0,04122567 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 0,01240418 0,04116801 ! galactose metabolic process GO:0006012 14 8 0,000 0,01240418 0,04111052 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01240418 0,04105318 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01240418 0,040996 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01240418 0,04093898 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 0,01240418 0,04088212 ! ruffle organization GO:0031529 12 8 0,000 0,01240418 0,04082542 ! osteoblast development GO:0002076 14 8 0,000 0,01240418 0,04076888 ! macroautophagy GO:0016236 14 8 0,000 0,01240418 0,04071249 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01240418 0,04065626 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01240418 0,04060018 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 0,01240418 0,04054425 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01240418 0,04048849 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 0,01240418 0,04043287 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 0,01240418 0,04037741 ! protein retention in ER lumen GO:0006621 16 8 0,000 0,01240418 0,04032209 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 0,01240418 0,04026693 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 0,01240418 0,04021192 ! regulation of circadian rhythm GO:0042752 13 8 0,000 0,01240418 0,04015707 ! pigment granule localization GO:0051875 14 8 0,000 0,01240418 0,04010236 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 0,01240418 0,04004779 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 0,01240418 0,03999338 ! response to tropane GO:0014073 14 8 0,000 0,01240418 0,03993912 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 0,01240418 0,039885 ! embryonic axis specification GO:0000578 12 8 0,000 0,01240418 0,03983103 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 0,01240418 0,0397772 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 0,01240418 0,03972352 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 0,01240418 0,03966999 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01240418 0,03961659 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01240418 0,03956335 ! regulation of focal adhesion formation GO:0051893 17 8 0,000 0,01240418 0,03951024 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01240418 0,03945728 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 0,01240418 0,03940446 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 0,01240418 0,03935178 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 0,01240418 0,03929924 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 0,01240418 0,03924684 ! establishment of nucleus localization GO:0040023 14 8 0,000 0,01240418 0,03919458 ! icosanoid secretion GO:0032309 12 8 0,000 0,01240418 0,03914246 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 0,01240418 0,03909048 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 0,01240418 0,03903863 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 0,01240418 0,03898693 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 0,01240418 0,03893536 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 0,01240418 0,03888392 ! S phase GO:0051320 8 8 0,000 0,01240418 0,03883262 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 0,01240418 0,03878146 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 0,01240418 0,03873043 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 0,01240418 0,03867954 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01240418 0,03862878 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 0,01240418 0,03857815 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01240418 0,03852766 ! melanin biosynthetic process GO:0042438 11 8 0,000 0,01240418 0,03847729 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01240418 0,03842706 ! regulation of synaptogenesis GO:0051963 12 8 0,000 0,01240418 0,03837696 ! hormone catabolic process GO:0042447 13 8 0,000 0,01240418 0,03832699 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 0,01240418 0,03827715 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01240418 0,03822744 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 0,01240418 0,03817786 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 0,01240418 0,03812841 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01240418 0,03807908 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01240418 0,03802988 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01240418 0,03798081 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 0,01240418 0,03793187 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01240418 0,03788305 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01240418 0,03783436 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 0,01240418 0,03778579 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 0,01240418 0,03773734 ! negative regulation of B cell activation GO:0050869 17 8 0,000 0,01240418 0,03768903 ! behavioral response to nicotine GO:0035095 13 8 0,000 0,01240418 0,03764083 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01240418 0,03759276 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 0,01240418 0,03754481 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 0,01240418 0,03749698 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 0,01240418 0,03744927 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 0,01240418 0,03740169 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,0139442 0,04199185 ! regulation of developmental growth GO:0048638 14 9 0,000 0,0139442 0,04193863 ! telencephalon cell migration GO:0022029 16 9 0,000 0,0139442 0,04188555 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 0,0139442 0,04183259 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 0,0139442 0,04177977 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 0,0139442 0,04172709 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 0,0139442 0,04167454 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 0,0139442 0,04162211 ! cell volume homeostasis GO:0006884 14 9 0,000 0,0139442 0,04156983 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 0,0139442 0,04151767 GO:0010469|regulation of receptor activity, ! UTP metabolic process GO:0046051 10 9 0,000 0,0139442 0,04146564 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 0,0139442 0,04141374 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 0,0139442 0,04136198 ! smoothened signaling pathway GO:0007224 10 9 0,000 0,0139442 0,04131034 ! protein complex disassembly GO:0043241 17 9 0,000 0,0139442 0,04125883 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,0139442 0,04120745 ! estrogen metabolic process GO:0008210 16 9 0,000 0,0139442 0,0411562 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,0139442 0,04110507 ! photoreceptor cell development GO:0042461 17 9 0,000 0,0139442 0,04105407 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 0,0139442 0,0410032 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 0,0139442 0,04095245 ! microtubule bundle formation GO:0001578 14 9 0,000 0,0139442 0,04090183 ! T-helper 1 type immune response GO:0042088 13 9 0,000 0,0139442 0,04085133 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 0,0139442 0,04080096 ! lung alveolus development GO:0048286 18 9 0,000 0,0139442 0,04075072 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,0139442 0,04070059 ! pseudouridine synthesis GO:0001522 10 9 0,000 0,0139442 0,04065059 ! endothelial cell differentiation GO:0045446 17 9 0,000 0,0139442 0,04060071 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,0139442 0,04055096 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,0139442 0,04050132 ! endoderm development GO:0007492 12 9 0,000 0,0139442 0,04045181 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,0139442 0,04040242 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,0139442 0,04035315 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 0,0139442 0,040304 ! astrocyte differentiation GO:0048708 17 9 0,000 0,0139442 0,04025497 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 0,0139442 0,04020605 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 0,0139442 0,04015726 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0139442 0,04010858 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 0,0139442 0,04006003 ! reverse cholesterol transport GO:0043691 17 9 0,000 0,0139442 0,04001159 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 0,0139442 0,03996326 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 0,0139442 0,03991506 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 0,0139442 0,03986697 ! macrophage activation GO:0042116 14 9 0,000 0,0139442 0,03981899 ! multicellular organism growth GO:0035264 16 9 0,000 0,0139442 0,03977113 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 0,0139442 0,03972339 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,0139442 0,03967576 ! neuron apoptosis GO:0051402 12 9 0,000 0,0139442 0,03962824 ! lens development in camera-type eye GO:0002088 11 9 0,000 0,0139442 0,03958084 ! positive regulation of vasodilation GO:0045909 14 9 0,000 0,0139442 0,03953355 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,0139442 0,03948637 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 0,0139442 0,03943931 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,0139442 0,03939236 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 0,0139442 0,03934552 ! Schwann cell differentiation GO:0014037 20 9 0,000 0,0139442 0,03929879 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 0,0139442 0,03925217 ! regulation of gliogenesis GO:0014013 21 9 0,000 0,0139442 0,03920566 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 0,0139442 0,03915927 ! oligodendrocyte development GO:0014003 13 9 0,000 0,0139442 0,03911298 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 0,0139442 0,0390668 ! segment specification GO:0007379 11 9 0,000 0,0139442 0,03902073 ! cellular extravasation GO:0045123 12 9 0,000 0,0139442 0,03897477 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0139442 0,03892892 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 0,0139442 0,03888317 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,0139442 0,03883754 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0139442 0,03879201 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 0,0139442 0,03874658 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 0,0139442 0,03870126 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 0,0139442 0,03865605 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 0,0139442 0,03861095 ! response to amine stimulus GO:0014075 13 9 0,000 0,0139442 0,03856595 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 0,0139442 0,03852105 ! erythrocyte development GO:0048821 13 9 0,000 0,0139442 0,03847626 ! renal water homeostasis GO:0003091 13 9 0,000 0,0139442 0,03843157 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 0,0139442 0,03838699 ! nucleosome disassembly GO:0006337 13 9 0,000 0,0139442 0,0383425 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 0,0139442 0,03829813 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 0,0139442 0,03825385 ! induction of an organ GO:0001759 13 9 0,000 0,0139442 0,03820968 ! leukocyte activation during immune response GO:0002366 15 9 0,000 0,0139442 0,03816561 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 0,0139442 0,03812164 ! cerebellum morphogenesis GO:0021587 13 9 0,000 0,0139442 0,03807777 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 0,0139442 0,038034 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0139442 0,03799033 ! sterol catabolic process GO:0016127 11 9 0,000 0,0139442 0,03794677 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 0,0139442 0,0379033 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,0139442 0,03785993 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 0,0139442 0,03781666 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 0,0139442 0,03777349 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 0,0139442 0,03773042 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 0,0139442 0,03768745 ! prophase GO:0051324 12 9 0,000 0,0139442 0,03764457 ! neuroblast proliferation GO:0007405 19 9 0,000 0,0139442 0,0376018 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 0,0139442 0,03755912 ! peptidyl-threonine modification GO:0018210 22 9 0,000 0,0139442 0,03751653 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 0,0139442 0,03747404 ! ubiquinone metabolic process GO:0006743 11 9 0,000 0,0139442 0,03743165 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 0,0139442 0,03738936 ! acid secretion GO:0046717 14 9 0,000 0,0139442 0,03734716 ! purine base metabolic process GO:0006144 18 9 0,000 0,0139442 0,03730505 ! detection of calcium ion GO:0005513 13 9 0,000 0,0139442 0,03726304 ! myeloid cell homeostasis GO:0002262 10 9 0,000 0,0139442 0,03722113 ! regulation of fibrinolysis GO:0051917 14 9 0,000 0,0139442 0,0371793 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,0139442 0,03713758 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 0,0139442 0,03709594 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 0,0139442 0,0370544 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,0139442 0,03701295 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0139442 0,0369716 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 0,0139442 0,03693034 ! prepulse inhibition GO:0060134 14 9 0,000 0,0139442 0,03688917 ! sequestering of metal ion GO:0051238 12 9 0,000 0,0139442 0,03684809 ! lamellipodium assembly GO:0030032 12 9 0,000 0,0139442 0,0368071 ! regulation of embryonic development GO:0045995 17 9 0,000 0,0139442 0,0367662 ! mitochondrion localization GO:0051646 15 9 0,000 0,0139442 0,0367254 ! localization within membrane GO:0051668 15 9 0,000 0,0139442 0,03668468 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01548189 0,04068496 ! axon extension GO:0048675 13 10 0,000 0,01548189 0,04063995 ! neuron fate specification GO:0048665 12 10 0,000 0,01548189 0,04059505 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,01548189 0,04055024 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,01548189 0,04050553 ! associative learning GO:0008306 19 10 0,000 0,01548189 0,04046092 ! positive regulation of B cell proliferation GO:0030890 14 10 0,000 0,01548189 0,04041641 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,01548189 0,040372 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01548189 0,04032768 ! CTP metabolic process GO:0046036 11 10 0,000 0,01548189 0,04028346 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,01548189 0,04023934 ! GTP metabolic process GO:0046039 11 10 0,000 0,01548189 0,04019532 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01548189 0,04015139 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,01548189 0,04010755 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01548189 0,04006382 ! social behavior GO:0035176 15 10 0,000 0,01548189 0,04002017 ! sulfate transport GO:0008272 12 10 0,000 0,01548189 0,03997663 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,01548189 0,03993317 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,01548189 0,03988981 ! artery development GO:0060840 20 10 0,000 0,01548189 0,03984655 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,01548189 0,03980338 ! response to pain GO:0048265 20 10 0,000 0,01548189 0,0397603 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,01548189 0,03971732 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,01548189 0,03967443 ! phospholipid efflux GO:0033700 17 10 0,000 0,01548189 0,03963163 ! hippocampus development GO:0021766 19 10 0,000 0,01548189 0,03958892 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,01548189 0,03954631 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,01548189 0,03950378 ! blood vessel remodeling GO:0001974 23 10 0,000 0,01548189 0,03946135 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01548189 0,03941901 ! pathogenesis GO:0009405 13 10 0,000 0,01548189 0,03937676 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01548189 0,0393346 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,01548189 0,03929253 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,01548189 0,03925055 ! protein targeting to ER GO:0045047 21 10 0,000 0,01548189 0,03920866 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,01548189 0,03916686 ! arginine catabolic process GO:0006527 12 10 0,000 0,01548189 0,03912515 ! melanocyte differentiation GO:0030318 16 10 0,000 0,01548189 0,03908353 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,01548189 0,039042 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01548189 0,03900055 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 0,000 0,01548189 0,03895919 ! regulation of stress fiber formation GO:0051492 24 10 0,000 0,01548189 0,03891792 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,01548189 0,03887674 ! B cell proliferation GO:0042100 16 10 0,000 0,01548189 0,03883564 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,01548189 0,03879463 ! mannose metabolic process GO:0006013 11 10 0,000 0,01548189 0,03875371 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01548189 0,03871288 ! forebrain cell migration GO:0021885 17 10 0,000 0,01548189 0,03867212 ! lipid digestion GO:0044241 15 10 0,000 0,01548189 0,03863146 ! substrate-bound cell migration GO:0006929 11 10 0,000 0,01548189 0,03859088 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01548189 0,03855039 ! receptor clustering GO:0043113 18 10 0,000 0,01548189 0,03850998 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01548189 0,03846965 ! UV protection GO:0009650 14 10 0,000 0,01548189 0,03842941 ! entry into host cell GO:0030260 21 10 0,000 0,01548189 0,03838926 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,01548189 0,03834918 ! behavioral fear response GO:0001662 19 10 0,000 0,01548189 0,0383092 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01548189 0,03826929 ! negative regulation of ossification GO:0030279 21 10 0,000 0,01548189 0,03822947 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,01548189 0,03818973 ! protein homotetramerization GO:0051289 20 10 0,000 0,01548189 0,03815007 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,01548189 0,0381105 ! response to dsRNA GO:0043331 19 10 0,000 0,01548189 0,038071 ! DNA ligation GO:0006266 16 10 0,000 0,01548189 0,03803159 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,01548189 0,03799226 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,01548189 0,03795301 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01548189 0,03791385 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01548189 0,03787476 ! positive regulation of Ras GTPase activity GO:0032320 24 10 0,000 0,01548189 0,03783576 ! postreplication repair GO:0006301 16 10 0,000 0,01548189 0,03779683 ! fucose catabolic process GO:0019317 17 10 0,000 0,01548189 0,03775798 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,01548189 0,03771922 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01548189 0,03768053 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,01548189 0,03764192 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,01548189 0,0376034 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,01548189 0,03756495 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01548189 0,03752658 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,01548189 0,03748828 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,01548189 0,03745007 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,01548189 0,03741193 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,01548189 0,03737387 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,01548189 0,03733589 ! oocyte differentiation GO:0009994 14 10 0,000 0,01548189 0,03729799 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,01548189 0,03726016 ! spleen development GO:0048536 17 10 0,000 0,01548189 0,03722241 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,01548189 0,03718474 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,01548189 0,03714714 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 0,01548189 0,03710961 ! blastocyst formation GO:0001825 14 10 0,000 0,01548189 0,03707217 ! embryonic gut development GO:0048566 13 10 0,000 0,01548189 0,0370348 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,01548189 0,0369975 ! cerebellar cortex development GO:0021695 14 10 0,000 0,01548189 0,03696028 ! activation of innate immune response GO:0002218 10 10 0,000 0,01548189 0,03692313 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01548189 0,03688606 ! insulin secretion GO:0030073 18 10 0,000 0,01548189 0,03684907 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 0,01548189 0,03681214 ! response to nicotine GO:0035094 18 10 0,000 0,01548189 0,03677529 ! establishment of cell polarity GO:0030010 12 10 0,000 0,01548189 0,03673852 ! nucleus localization GO:0051647 16 10 0,000 0,01548189 0,03670182 ! regulation of synapse organization GO:0050807 14 10 0,000 0,01548189 0,03666519 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,01701726 0,04026117 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,01701726 0,04022106 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,01701726 0,04018104 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,01701726 0,0401411 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,01701726 0,04010124 ! virus-host interaction GO:0019048 20 11 0,000 0,01701726 0,04006146 ! thyroid gland development GO:0030878 20 11 0,000 0,01701726 0,04002175 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,01701726 0,03998213 GO:0006740|NADPH regeneration, ! regulation of phosphatase activity GO:0010921 23 11 0,000 0,01701726 0,03994258 ! non-recombinational repair GO:0000726 19 11 0,000 0,01701726 0,03990311 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,01701726 0,03986372 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,01701726 0,03982441 ! Golgi vesicle budding GO:0048194 18 11 0,000 0,01701726 0,03978517 ! elastic fiber assembly GO:0048251 17 11 0,000 0,01701726 0,03974601 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,01701726 0,03970693 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,01701726 0,03966793 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,01701726 0,039629 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,01701726 0,03959015 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,01701726 0,03955137 ! bone resorption GO:0045453 16 11 0,000 0,01701726 0,03951267 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,01701726 0,03947405 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,01701726 0,0394355 ! ventral spinal cord development GO:0021517 15 11 0,000 0,01701726 0,03939702 ! regulated secretory pathway GO:0045055 15 11 0,000 0,01701726 0,03935862 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 0,01701726 0,0393203 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,01701726 0,03928205 ! syncytium formation GO:0006949 15 11 0,000 0,01701726 0,03924388 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01701726 0,03920578 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,01701726 0,03916775 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,01701726 0,0391298 ! Golgi organization GO:0007030 19 11 0,000 0,01701726 0,03909192 ! response to X-ray GO:0010165 19 11 0,000 0,01701726 0,03905411 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,01701726 0,03901638 ! adult heart development GO:0007512 12 11 0,000 0,01701726 0,03897871 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01701726 0,03894113 ! epithelial cell development GO:0002064 16 11 0,000 0,01701726 0,03890361 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,01701726 0,03886617 ! temperature homeostasis GO:0001659 16 11 0,000 0,01701726 0,0388288 ! L-glutamate transport GO:0015813 15 11 0,000 0,01701726 0,0387915 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,01701726 0,03875427 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01701726 0,03871711 ! motor axon guidance GO:0008045 17 11 0,000 0,01701726 0,03868003 ! copper ion homeostasis GO:0055070 15 11 0,000 0,01701726 0,03864301 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,01701726 0,03860607 ! regulation of bone resorption GO:0045124 27 11 0,000 0,01701726 0,0385692 ! stem cell development GO:0048864 30 11 0,000 0,01701726 0,03853239 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,01701726 0,03849566 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,01701726 0,038459 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,01701726 0,03842241 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,01701726 0,03838588 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,01701726 0,03834943 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01701726 0,03831304 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,01701726 0,03827673 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,01701726 0,03824048 ! cranial nerve development GO:0021545 14 11 0,000 0,01701726 0,0382043 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01701726 0,03816819 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01701726 0,03813215 ! salivary gland development GO:0007431 24 11 0,000 0,01701726 0,03809618 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,01701726 0,03806027 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,01701726 0,03802443 ! musculoskeletal movement GO:0050881 16 11 0,000 0,01701726 0,03798866 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,01701726 0,03795296 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01701726 0,03791732 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01701726 0,03788175 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 19 11 0,000 0,01701726 0,03784625 ! cholesterol efflux GO:0033344 20 11 0,000 0,01701726 0,03781081 ! digestive tract morphogenesis GO:0048546 16 11 0,000 0,01701726 0,03777544 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,01701726 0,03774014 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,01701726 0,0377049 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 0,01701726 0,03766973 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01701726 0,03763462 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,01701726 0,03759958 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01701726 0,0375646 ! regulation of actin filament bundle formation GO:0032231 25 11 0,000 0,01701726 0,03752969 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,01701726 0,03749485 ! defense response to fungus GO:0050832 13 11 0,000 0,01701726 0,03746006 ! lysogeny GO:0030069 20 11 0,000 0,01701726 0,03742535 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,01701726 0,03739069 ! acrosome reaction GO:0007340 14 11 0,000 0,01701726 0,0373561 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,01701726 0,03732158 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,01701726 0,03728712 ! rRNA transcription GO:0009303 19 12 0,000 0,01855031 0,04060875 ! reproductive cellular process GO:0048610 15 12 0,000 0,01855031 0,04057132 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01855031 0,04053396 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01855031 0,04049667 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01855031 0,04045945 ! phosphate transport GO:0006817 15 12 0,000 0,01855031 0,0404223 ! positive regulation of GTPase activity GO:0043547 29 12 0,000 0,01855031 0,04038521 ! peroxisomal transport GO:0043574 22 12 0,000 0,01855031 0,04034819 ! mating GO:0007618 16 12 0,000 0,01855031 0,04031125 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01855031 0,04027436 ! heart looping GO:0001947 15 12 0,000 0,01855031 0,04023755 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01855031 0,0402008 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01855031 0,04016412 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01855031 0,04012751 ! T cell selection GO:0045058 25 12 0,000 0,01855031 0,04009097 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01855031 0,04005449 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01855031 0,04001807 ! plasma membrane organization GO:0007009 19 12 0,000 0,01855031 0,03998173 ! focal adhesion formation GO:0048041 28 12 0,000 0,01855031 0,03994544 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01855031 0,03990923 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01855031 0,03987308 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01855031 0,039837 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01855031 0,03980098 ! monoamine transport GO:0015844 14 12 0,000 0,01855031 0,03976502 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01855031 0,03972913 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01855031 0,03969331 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01855031 0,03965755 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01855031 0,03962185 ! regulation of organ growth GO:0046620 14 12 0,000 0,01855031 0,03958622 ! vasoconstriction GO:0042310 18 12 0,000 0,01855031 0,03955066 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01855031 0,03951515 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01855031 0,03947971 ! regulation of Rho GTPase activity GO:0032319 22 12 0,000 0,01855031 0,03944434 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01855031 0,03940902 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01855031 0,03937377 ! histone deacetylation GO:0016575 14 12 0,000 0,01855031 0,03933859 ! histone acetylation GO:0016573 27 12 0,000 0,01855031 0,03930346 ! DNA methylation GO:0006306 19 12 0,000 0,01855031 0,0392684 GO:0006305|DNA alkylation, ! protein sumoylation GO:0016925 14 12 0,000 0,01855031 0,0392334 ! chromatin silencing GO:0006342 23 12 0,000 0,01855031 0,03919847 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01855031 0,03916359 ! gland morphogenesis GO:0022612 24 12 0,000 0,01855031 0,03912878 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01855031 0,03909403 ! zymogen activation GO:0031638 16 12 0,000 0,01855031 0,03905934 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01855031 0,03902472 ! nucleosome positioning GO:0016584 13 12 0,000 0,01855031 0,03899015 ! T cell homeostasis GO:0043029 22 12 0,000 0,01855031 0,03895565 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01855031 0,0389212 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01855031 0,03888682 ! response to gamma radiation GO:0010332 21 12 0,000 0,01855031 0,0388525 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01855031 0,03881824 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01855031 0,03878404 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01855031 0,03874989 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01855031 0,03871581 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01855031 0,03868179 ! male genitalia development GO:0030539 15 12 0,000 0,01855031 0,03864783 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01855031 0,03861393 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01855031 0,03858009 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01855031 0,0385463 ! developmental induction GO:0031128 16 12 0,000 0,01855031 0,03851258 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,01855031 0,03847892 ! response to cold GO:0009409 15 12 0,000 0,01855031 0,03844531 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01855031 0,03841176 ! respiratory burst GO:0045730 22 13 0,000 0,02008105 0,04154518 ! lactation GO:0007595 22 13 0,000 0,02008105 0,04150899 ! tRNA modification GO:0006400 15 13 0,000 0,02008105 0,04147286 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,02008105 0,0414368 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,02008105 0,0414008 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02008105 0,04136486 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,02008105 0,04132899 ! water transport GO:0006833 21 13 0,000 0,02008105 0,04129317 GO:0042044|fluid transport, ! regulation of B cell proliferation GO:0030888 24 13 0,000 0,02008105 0,04125742 ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,02008105 0,04122173 ! copper ion transport GO:0006825 15 13 0,000 0,02008105 0,0411861 ! filopodium assembly GO:0046847 21 13 0,000 0,02008105 0,04115054 ! lipid localization GO:0010876 25 13 0,000 0,02008105 0,04111503 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,02008105 0,04107959 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,02008105 0,0410442 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,02008105 0,04100888 ! T cell proliferation GO:0042098 24 13 0,000 0,02008105 0,04097362 ! organelle fusion GO:0048284 29 13 0,000 0,02008105 0,04093842 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02008105 0,04090328 ! endocrine pancreas development GO:0031018 19 13 0,000 0,02008105 0,0408682 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,02008105 0,04083318 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,02008105 0,04079822 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,02008105 0,04076332 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,02008105 0,04072848 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,02008105 0,0406937 ! methionine metabolic process GO:0006555 16 13 0,000 0,02008105 0,04065898 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,02008105 0,04062431 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02008105 0,04058971 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,02008105 0,04055517 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,02008105 0,04052068 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,02008105 0,04048625 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,02008105 0,04045188 ! neutral amino acid transport GO:0015804 20 13 0,000 0,02008105 0,04041757 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,02008105 0,04038332 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,02008105 0,04034913 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,02008105 0,04031499 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,02008105 0,04028091 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02008105 0,04024689 ! cellular pigmentation GO:0033059 24 13 0,000 0,02008105 0,04021293 ! histone methylation GO:0016571 16 13 0,000 0,02008105 0,04017902 ! regulation of epidermis development GO:0045682 21 13 0,000 0,02008105 0,04014517 ! oxygen transport GO:0015671 20 13 0,000 0,02008105 0,04011138 ! regulation of axon extension GO:0030516 26 13 0,000 0,02008105 0,04007765 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,02008105 0,04004397 ! detection of bacterium GO:0016045 13 13 0,000 0,02008105 0,04001034 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,02008105 0,03997678 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,02008105 0,03994327 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,02008105 0,03990982 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,02008105 0,03987642 ! actin filament polymerization GO:0030041 18 13 0,000 0,02008105 0,03984308 ! regulation of protein ubiquitination GO:0031396 20 14 0,000 0,02160947 0,04283983 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,02160947 0,04280407 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,02160947 0,04276837 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,02160947 0,04273273 ! neuron maturation GO:0042551 24 14 0,000 0,02160947 0,04269715 ! regulation of S phase GO:0033261 25 14 0,000 0,02160947 0,04266163 ! regulation of chemokine production GO:0032642 18 14 0,000 0,02160947 0,04262617 ! myotube differentiation GO:0014902 21 14 0,000 0,02160947 0,04259076 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,02160947 0,04255542 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,02160947 0,04252013 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,02160947 0,0424849 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,02160947 0,04244973 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,02160947 0,04241462 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,02160947 0,04237957 ! cartilage condensation GO:0001502 22 14 0,000 0,02160947 0,04234457 ! gene silencing by RNA GO:0031047 22 14 0,000 0,02160947 0,04230964 ! response to cAMP GO:0051591 20 14 0,000 0,02160947 0,04227475 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,02160947 0,04223993 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,02160947 0,04220517 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,02160947 0,04217046 ! limbic system development GO:0021761 25 14 0,000 0,02160947 0,04213581 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,02160947 0,04210121 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,02160947 0,04206668 ! palate development GO:0060021 19 14 0,000 0,02160947 0,04203219 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,02160947 0,04199777 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,02160947 0,0419634 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,02160947 0,04192909 ! response to hexose stimulus GO:0009746 22 14 0,000 0,02160947 0,04189483 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,02160947 0,04186063 ! arginine metabolic process GO:0006525 17 14 0,000 0,02160947 0,04182649 ! glutamate metabolic process GO:0006536 21 14 0,000 0,02160947 0,0417924 ! glycine metabolic process GO:0006544 22 14 0,000 0,02160947 0,04175837 ! pituitary gland development GO:0021983 24 14 0,000 0,02160947 0,04172439 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,02160947 0,04169047 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,02160947 0,0416566 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,02160947 0,04162279 ! cytokine metabolic process GO:0042107 18 14 0,000 0,02160947 0,04158903 ! NAD metabolic process GO:0019674 25 14 0,000 0,02160947 0,04155533 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,02160947 0,04152168 ! regulation of heart rate GO:0002027 26 14 0,000 0,02160947 0,04148809 ! exocrine system development GO:0035272 29 14 0,000 0,02160947 0,04145455 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02160947 0,04142106 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,02160947 0,04138763 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,02160947 0,04135426 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,02160947 0,04132093 ! axon cargo transport GO:0008088 29 14 0,000 0,02160947 0,04128766 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,02160947 0,04125445 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,02160947 0,04122128 ! genitalia development GO:0048806 18 14 0,000 0,02160947 0,04118817 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,02160947 0,04115512 ! autonomic nervous system development GO:0048483 26 14 0,000 0,02160947 0,04112212 ! tissue regeneration GO:0042246 24 14 0,000 0,02160947 0,04108916 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,02160947 0,04105627 ! water homeostasis GO:0030104 23 14 0,000 0,02160947 0,04102342 ! cofactor transport GO:0051181 22 14 0,000 0,02160947 0,04099063 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,02160947 0,04095789 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,02160947 0,0409252 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,02160947 0,04089257 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02160947 0,04085998 ! cell killing GO:0001906 22 14 0,000 0,02160947 0,04082745 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,02160947 0,04079497 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,02160947 0,04076254 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,02160947 0,04073016 GO:0042130|negative regulation of T cell proliferation, ! microspike assembly GO:0030035 25 14 0,000 0,02160947 0,04069784 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,02160947 0,04066557 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,02313559 0,04350298 ! superoxide anion generation GO:0042554 19 15 0,000 0,02313559 0,04346854 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,02313559 0,04343415 ! skin development GO:0043588 28 15 0,000 0,02313559 0,04339981 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,02313559 0,04336553 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,02313559 0,0433313 ! inositol metabolic process GO:0006020 21 15 0,000 0,02313559 0,04329713 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,02313559 0,04326301 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,02313559 0,04322894 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,02313559 0,04319493 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,02313559 0,04316097 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02313559 0,04312707 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,02313559 0,04309322 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,02313559 0,04305942 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,02313559 0,04302567 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02313559 0,04299198 ! response to osmotic stress GO:0006970 23 15 0,000 0,02313559 0,04295834 ! vesicle coating GO:0006901 26 15 0,000 0,02313559 0,04292475 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,02313559 0,04289122 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,02313559 0,04285774 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,02313559 0,04282431 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,02313559 0,04279093 ! bone mineralization GO:0030282 17 15 0,000 0,02313559 0,0427576 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,02313559 0,04272433 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,02313559 0,0426911 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,02313559 0,04265793 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,02313559 0,04262481 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,02313559 0,04259175 ! regulation of cellular pH GO:0030641 23 15 0,000 0,02313559 0,04255873 ! ribosome assembly GO:0042255 17 15 0,000 0,02313559 0,04252576 ! cerebellum development GO:0021549 19 15 0,000 0,02313559 0,04249285 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,02313559 0,04245998 ! mRNA splice site selection GO:0006376 33 15 0,000 0,02313559 0,04242717 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,02313559 0,04239441 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,02313559 0,0423617 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,02313559 0,04232904 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,02313559 0,04229643 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,02313559 0,04226386 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,02313559 0,04223135 ! muscle maintenance GO:0046716 21 15 0,000 0,02313559 0,04219889 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,02313559 0,04216648 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,02313559 0,04213412 ! intestinal absorption GO:0050892 22 15 0,000 0,02313559 0,04210181 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,02313559 0,04206955 ! dopamine metabolic process GO:0042417 32 15 0,000 0,02313559 0,04203734 ! gas transport GO:0015669 23 15 0,000 0,02313559 0,04200517 ! organic cation transport GO:0015695 19 15 0,000 0,02313559 0,04197306 ! heme biosynthetic process GO:0006783 22 15 0,000 0,02313559 0,04194099 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,02313559 0,04190898 ! lymphocyte homeostasis GO:0002260 29 15 0,000 0,02313559 0,04187701 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,02313559 0,04184509 ! release of cytochrome c from mitochondria GO:0001836 29 15 0,000 0,02313559 0,04181322 ! cilium assembly GO:0042384 22 15 0,000 0,02313559 0,0417814 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,02313559 0,04174963 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,02313559 0,0417179 ! peptide hormone processing GO:0016486 23 15 0,000 0,02313559 0,04168623 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,02313559 0,0416546 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,02465941 0,0443645 ! bone remodeling GO:0046849 24 16 0,000 0,02465941 0,04433089 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,02465941 0,04429733 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,02465941 0,04426382 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,02465941 0,04423037 ! bile acid metabolic process GO:0008206 23 16 0,000 0,02465941 0,04419696 ! axis specification GO:0009798 26 16 0,000 0,02465941 0,0441636 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,02465941 0,0441303 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,02465941 0,04409704 ! positive regulation of cell growth GO:0030307 22 16 0,000 0,02465941 0,04406384 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02465941 0,04403068 ! centrosome cycle GO:0007098 18 16 0,000 0,02465941 0,04399758 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,02465941 0,04396452 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,02465941 0,04393151 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,02465941 0,04389856 ! cellular response to starvation GO:0009267 26 16 0,000 0,02465941 0,04386565 ! DNA integration GO:0015074 25 16 0,000 0,02465941 0,04383279 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,02465941 0,04379998 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,02465941 0,04376722 ! regulation of exocytosis GO:0017157 28 16 0,000 0,02465941 0,04373451 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,02465941 0,04370185 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,02465941 0,04366924 ! regulation of vasodilation GO:0042312 26 16 0,000 0,02465941 0,04363667 ! DNA replication initiation GO:0006270 26 16 0,000 0,02465941 0,04360415 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,02465941 0,04357169 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,02465941 0,04353927 ! neuron recognition GO:0008038 27 16 0,000 0,02465941 0,0435069 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,02465941 0,04347457 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,02465941 0,0434423 ! G1 phase GO:0051318 28 16 0,000 0,02465941 0,04341007 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,02465941 0,04337789 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02465941 0,04334576 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,02465941 0,04331368 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,02465941 0,04328164 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,02465941 0,04324965 ! NADP metabolic process GO:0006739 22 16 0,000 0,02465941 0,04321771 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,02465941 0,04318581 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,02465941 0,04315396 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,02465941 0,04312216 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,02465941 0,04309041 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02465941 0,0430587 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,02465941 0,04302704 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,02465941 0,04299543 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,02465941 0,04296386 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,02465941 0,04293234 ! defense response to virus GO:0051607 28 16 0,000 0,02465941 0,04290086 ! peptide hormone secretion GO:0030072 26 16 0,000 0,02465941 0,04286943 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,02618092 0,04548121 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,02618092 0,04544794 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,02618092 0,04541472 ! zinc ion transport GO:0006829 22 17 0,000 0,02618092 0,04538154 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02618092 0,04534842 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,02618092 0,04531534 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,02618092 0,04528231 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,02618092 0,04524933 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,02618092 0,0452164 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,02618092 0,04518351 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,02618092 0,04515068 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,02618092 0,04511789 ! adult walking behavior GO:0007628 30 17 0,000 0,02618092 0,04508515 ! patterning of blood vessels GO:0001569 27 17 0,000 0,02618092 0,04505245 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,02618092 0,04501981 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,02618092 0,04498721 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 25 17 0,000 0,02618092 0,04495465 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02618092 0,04492215 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,02618092 0,04488969 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,02618092 0,04485728 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,02618092 0,04482491 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02618092 0,0447926 ! protein polyubiquitination GO:0000209 31 17 0,000 0,02618092 0,04476033 ! cerebral cortex development GO:0021987 34 17 0,000 0,02618092 0,0447281 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,02618092 0,04469592 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02618092 0,04466379 ! fructose metabolic process GO:0006000 24 17 0,000 0,02618092 0,0446317 ! membrane budding GO:0006900 30 17 0,000 0,02618092 0,04459966 ! neuromuscular junction development GO:0007528 25 17 0,000 0,02618092 0,04456767 ! L-amino acid transport GO:0015807 27 17 0,000 0,02618092 0,04453572 ! regulation of protein binding GO:0043393 29 17 0,000 0,02618092 0,04450382 ! peptide secretion GO:0002790 30 17 0,000 0,02618092 0,04447196 ! stem cell differentiation GO:0048863 40 17 0,000 0,02618092 0,04444015 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02618092 0,04440839 ! intermediate filament-based process GO:0045103 29 17 0,000 0,02618092 0,04437667 ! protein export from nucleus GO:0006611 26 17 0,000 0,02618092 0,04434499 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,02618092 0,04431336 ! diencephalon development GO:0021536 27 17 0,000 0,02618092 0,04428178 ! oogenesis GO:0048477 25 17 0,000 0,02618092 0,04425024 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,02618092 0,04421874 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,02618092 0,04418729 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02618092 0,04415589 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,02618092 0,04412453 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,02618092 0,04409321 ! steroid catabolic process GO:0006706 24 17 0,000 0,02618092 0,04406194 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,02618092 0,04403071 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,02618092 0,04399953 ! nerve development GO:0021675 20 17 0,000 0,02618092 0,04396839 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,02618092 0,04393729 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,02618092 0,04390624 ! protein secretion GO:0009306 32 18 0,000 0,02770014 0,04642121 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,02770014 0,04638845 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,02770014 0,04635574 ! negative regulation of defense response GO:0031348 21 18 0,000 0,02770014 0,04632307 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,02770014 0,04629045 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,02770014 0,04625787 ! metencephalon development GO:0022037 25 18 0,000 0,02770014 0,04622534 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,02770014 0,04619286 ! hormone secretion GO:0046879 28 18 0,000 0,02770014 0,04616042 ! signal complex assembly GO:0007172 32 18 0,000 0,02770014 0,04612803 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,02770014 0,04609568 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02770014 0,04606338 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,02770014 0,04603112 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,02770014 0,04599891 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02770014 0,04596674 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,02770014 0,04593462 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,02770014 0,04590254 ! glial cell development GO:0021782 31 18 0,000 0,02770014 0,04587051 ! keratinization GO:0031424 19 18 0,000 0,02770014 0,04583852 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,02770014 0,04580658 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,02770014 0,04577468 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,02770014 0,04574282 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,02770014 0,04571101 ! vacuolar transport GO:0007034 26 18 0,000 0,02770014 0,04567925 ! pigmentation during development GO:0048066 35 18 0,000 0,02770014 0,04564753 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,02770014 0,04561585 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,02770014 0,04558421 ! fucose metabolic process GO:0006004 27 18 0,000 0,02770014 0,04555262 ! actin filament bundle formation GO:0051017 30 18 0,000 0,02770014 0,04552108 ! body fluid secretion GO:0007589 27 18 0,000 0,02770014 0,04548958 ! regulation of dephosphorylation GO:0035303 38 18 0,000 0,02770014 0,04545812 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,02770014 0,0454267 ! negative regulation of immune response GO:0050777 33 18 0,000 0,02770014 0,04539533 ! heart process GO:0003015 32 18 0,000 0,02770014 0,045364 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,02770014 0,04533272 ! sensory perception of pain GO:0019233 26 18 0,000 0,02770014 0,04530147 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,02770014 0,04527027 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,02770014 0,04523912 ! somitogenesis GO:0001756 25 18 0,000 0,02770014 0,045208 ! neural crest cell migration GO:0001755 28 18 0,000 0,02770014 0,04517693 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,02770014 0,04514591 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,02770014 0,04511492 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,02770014 0,04508398 ! synaptogenesis GO:0007416 28 18 0,000 0,02770014 0,04505308 ! cell-cell junction organization GO:0045216 28 18 0,000 0,02770014 0,04502222 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02770014 0,0449914 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,02770014 0,04496063 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,02770014 0,0449299 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,02770014 0,04489921 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,02770014 0,04486856 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,02770014 0,04483795 ! gut development GO:0048565 29 18 0,000 0,02770014 0,04480739 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,02770014 0,04477686 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,02770014 0,04474638 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,02770014 0,04471594 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,02921707 0,04713263 ! positive regulation of translation GO:0045727 29 19 0,000 0,02921707 0,04710061 ! positive regulation of cell size GO:0045793 26 19 0,000 0,02921707 0,04706864 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,02921707 0,0470367 ! glycerol metabolic process GO:0006071 22 19 0,000 0,02921707 0,04700481 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,02921707 0,04697297 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,02921707 0,04694116 ! endothelial cell migration GO:0043542 24 19 0,000 0,02921707 0,0469094 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,02921707 0,04687769 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,02921707 0,04684601 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,02921707 0,04681438 ! memory GO:0007613 28 19 0,000 0,02921707 0,04678279 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,02921707 0,04675125 ! pancreas development GO:0031016 27 19 0,000 0,02921707 0,04671974 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,02921707 0,04668828 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,02921707 0,04665686 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,02921707 0,04662549 ! central nervous system neuron development GO:0021954 33 19 0,000 0,02921707 0,04659415 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,02921707 0,04656286 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,02921707 0,04653161 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,02921707 0,0465004 ! heme metabolic process GO:0042168 29 19 0,000 0,02921707 0,04646924 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,02921707 0,04643811 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,02921707 0,04640703 ! response to fungus GO:0009620 21 19 0,000 0,02921707 0,04637599 ! peptide cross-linking GO:0018149 35 19 0,000 0,02921707 0,04634499 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,02921707 0,04631403 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,02921707 0,04628311 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,02921707 0,04625224 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,02921707 0,0462214 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,02921707 0,04619061 ! vitamin transport GO:0051180 26 19 0,000 0,02921707 0,04615985 ! sarcomere organization GO:0045214 26 19 0,000 0,02921707 0,04612914 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,02921707 0,04609847 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,02921707 0,04606784 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,02921707 0,04603725 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,02921707 0,0460067 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,02921707 0,04597619 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,02921707 0,04594573 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,0307317 0,04829558 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,0307317 0,04826362 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,0307317 0,0482317 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,0307317 0,04819982 ! lipid phosphorylation GO:0046834 28 20 0,000 0,0307317 0,04816798 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,0307317 0,04813619 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,0307317 0,04810444 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,0307317 0,04807273 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,0307317 0,04804106 ! response to alkaloid GO:0043279 34 20 0,000 0,0307317 0,04800943 ! sensory perception of taste GO:0050909 26 20 0,000 0,0307317 0,04797785 ! response to retinoic acid GO:0032526 27 20 0,000 0,0307317 0,0479463 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,0307317 0,0479148 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,0307317 0,04788334 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,0307317 0,04785192 ! chromosome condensation GO:0030261 32 20 0,000 0,0307317 0,04782054 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,0307317 0,04778921 ! sex determination GO:0007530 32 20 0,000 0,0307317 0,04775791 ! plasma membrane fusion GO:0045026 24 20 0,000 0,0307317 0,04772665 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,0307317 0,04769544 ! cytolysis GO:0019835 21 20 0,000 0,0307317 0,04766427 ! renal system process GO:0003014 35 20 0,000 0,0307317 0,04763313 ! vasodilation GO:0042311 36 20 0,000 0,0307317 0,04760204 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,0307317 0,04757099 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,0307317 0,04753998 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,0307317 0,04750901 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,0307317 0,04747808 ! hormone transport GO:0009914 30 20 0,000 0,0307317 0,04744719 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,0307317 0,04741634 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,0307317 0,04738553 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,0307317 0,04735476 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,0307317 0,04732403 ! sperm-egg recognition GO:0035036 24 20 0,000 0,0307317 0,04729334 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,0307317 0,04726269 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,0307317 0,04723208 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,03224405 0,04952435 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,03224405 0,04949232 ! positive regulation of fibroblast proliferation GO:0048146 30 21 0,000 0,03224405 0,04946033 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03224405 0,04942838 ! positive regulation of ossification GO:0045778 34 21 0,000 0,03224405 0,04939647 ! iron ion transport GO:0006826 49 21 0,000 0,03224405 0,0493646 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,03224405 0,04933277 ! microtubule-based transport GO:0010970 41 21 0,000 0,03224405 0,04930098 ! vesicle docking GO:0048278 28 21 0,000 0,03224405 0,04926924 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,03224405 0,04923753 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,03224405 0,04920587 ! apoptotic mitochondrial changes GO:0008637 42 21 0,000 0,03224405 0,04917425 ! response to ethanol GO:0045471 38 21 0,000 0,03224405 0,04914266 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,03224405 0,04911112 ! smooth muscle contraction GO:0006939 39 21 0,000 0,03224405 0,04907962 ! glutamine metabolic process GO:0006541 29 21 0,000 0,03224405 0,04904816 ! response to vitamin A GO:0033189 28 21 0,000 0,03224405 0,04901674 ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,03224405 0,04898536 ! apoptotic nuclear changes GO:0030262 31 21 0,000 0,03224405 0,04895402 ! response to starvation GO:0042594 35 21 0,000 0,03224405 0,04892272 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,03224405 0,04889146 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,03224405 0,04886023 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,03224405 0,04882905 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,03224405 0,04879791 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,03224405 0,04876681 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,03224405 0,04873575 ! visual learning GO:0008542 38 21 0,000 0,03224405 0,04870473 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 0,000 0,03224405 0,04867375 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,03224405 0,0486428 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,03224405 0,0486119 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03224405 0,04858103 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,03224405 0,04855021 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,03224405 0,04851942 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03224405 0,04848867 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,03224405 0,04845797 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,03224405 0,0484273 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,03224405 0,04839667 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,03224405 0,04836607 ! embryonic pattern specification GO:0009880 34 22 0,000 0,03375411 0,05059918 ! regulation of cell killing GO:0031341 37 22 0,000 0,03375411 0,05056724 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,03375411 0,05053534 ! gluconeogenesis GO:0006094 26 22 0,000 0,03375411 0,05050347 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,03375411 0,05047165 ! viral genome replication GO:0019079 31 22 0,000 0,03375411 0,05043987 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,03375411 0,05040812 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,03375411 0,05037642 ! protein amino acid acylation GO:0043543 42 22 0,000 0,03375411 0,05034476 ! response to vitamin GO:0033273 31 22 0,000 0,03375411 0,05031313 ! molting cycle process GO:0022404 43 22 0,000 0,03375411 0,05028155 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,03375411 0,05025001 ! regeneration GO:0031099 37 22 0,000 0,03375411 0,0502185 ! phototransduction GO:0007602 29 22 0,000 0,03375411 0,05018704 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,03375411 0,05015561 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,03375411 0,05012422 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,03375411 0,05009288 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,03375411 0,05006157 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,03375411 0,0500303 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,03375411 0,04999907 ! pallium development GO:0021543 43 22 0,000 0,03375411 0,04996788 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,03375411 0,04993673 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,03375411 0,04990561 ! platelet activation GO:0030168 33 22 0,000 0,03375411 0,04987454 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,03375411 0,0498435 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,03375411 0,04981251 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,03375411 0,04978155 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,03375411 0,04975063 ! cell-cell recognition GO:0009988 28 22 0,000 0,03375411 0,04971974 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,03375411 0,0496889 ! neural tube closure GO:0001843 35 22 0,000 0,03375411 0,0496581 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,03375411 0,04962733 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,03375411 0,0495966 ! protein tetramerization GO:0051262 43 22 0,000 0,03375411 0,04956591 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,0352619 0,05174798 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,0352619 0,05171599 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,0352619 0,05168405 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,0352619 0,05165215 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,0352619 0,05162028 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,0352619 0,05158846 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,0352619 0,05155667 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,0352619 0,05152493 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,0352619 0,05149322 ! tube lumen formation GO:0035148 37 23 0,000 0,0352619 0,05146155 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,0352619 0,05142992 ! dendrite development GO:0016358 41 23 0,000 0,0352619 0,05139833 ! vasculogenesis GO:0001570 38 23 0,000 0,0352619 0,05136678 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,0352619 0,05133526 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,0352619 0,05130379 ! lysosome organization GO:0007040 41 23 0,000 0,0352619 0,05127235 ! digestive system process GO:0022600 35 23 0,000 0,0352619 0,05124095 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,0352619 0,0512096 ! vesicle targeting GO:0006903 35 23 0,000 0,0352619 0,05117827 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,0352619 0,05114699 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,0352619 0,05111575 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,0352619 0,05108454 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,0352619 0,05105337 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,0352619 0,05102224 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,0352619 0,05099115 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,0352619 0,0509601 ! membrane depolarization GO:0051899 40 23 0,000 0,0352619 0,05092908 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,0352619 0,0508981 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,0352619 0,05086716 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,0352619 0,05083626 ! collagen fibril organization GO:0030199 50 23 0,000 0,0352619 0,05080539 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,0352619 0,05077456 ! cellular response to extracellular stimulus GO:0031668 37 23 0,000 0,0352619 0,05074377 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,0352619 0,05071302 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,0352619 0,0506823 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,0352619 0,05065162 ! positive regulation of B cell activation GO:0050871 36 23 0,000 0,0352619 0,05062098 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,0352619 0,05059037 ! collagen catabolic process GO:0030574 29 23 0,000 0,0352619 0,05055981 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,0352619 0,05052927 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,0352619 0,05049878 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,0352619 0,05046832 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,0352619 0,0504379 ! blastocyst development GO:0001824 41 23 0,000 0,0352619 0,05040752 ! actin filament-based movement GO:0030048 37 23 0,000 0,0352619 0,05037717 ! protein stabilization GO:0050821 34 23 0,000 0,0352619 0,05034686 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,0367674 0,05246485 ! myelination GO:0042552 39 24 0,000 0,0367674 0,05243332 ! initiation of viral infection GO:0019059 47 24 0,000 0,0367674 0,05240183 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,0367674 0,05237038 ! leukocyte adhesion GO:0007159 49 24 0,000 0,0367674 0,05233896 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,0367674 0,05230758 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,0367674 0,05227624 ! visual behavior GO:0007632 42 24 0,000 0,0367674 0,05224494 ! spinal cord development GO:0021510 41 24 0,000 0,0367674 0,05221367 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,0367674 0,05218244 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 0,000 0,0367674 0,05215125 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,0367674 0,0521201 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,0367674 0,05208898 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,0367674 0,0520579 ! cell aging GO:0007569 38 24 0,000 0,0367674 0,05202686 ! osteoblast differentiation GO:0001649 43 24 0,000 0,0367674 0,05199586 ! response to toxin GO:0009636 38 24 0,000 0,0367674 0,05196489 ! primary neural tube formation GO:0014020 37 24 0,000 0,0367674 0,05193396 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,0367674 0,05190306 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,0367674 0,0518722 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,0367674 0,05184138 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,0367674 0,0518106 ! immunoglobulin production GO:0002377 37 24 0,000 0,0367674 0,05177985 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,0367674 0,05174914 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,0367674 0,05171846 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,0367674 0,05168782 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,0367674 0,05165722 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,0367674 0,05162665 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,0367674 0,05159612 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,0367674 0,05156563 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,0367674 0,05153517 ! regulation of fibroblast proliferation GO:0048145 39 25 0,000 0,03827063 0,05361052 ! neuron fate commitment GO:0048663 38 25 0,000 0,03827063 0,05357889 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,03827063 0,0535473 ! superoxide metabolic process GO:0006801 33 25 0,000 0,03827063 0,05351574 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,03827063 0,05348423 GO:0050908|detection of light stimulus involved in visual perception, ! regulation of cell-matrix adhesion GO:0001952 57 25 0,000 0,03827063 0,05345275 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,03827063 0,0534213 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,03827063 0,0533899 ! vacuole organization GO:0007033 43 25 0,000 0,03827063 0,05335853 ! receptor metabolic process GO:0043112 40 25 0,000 0,03827063 0,0533272 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,03827063 0,0532959 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,03827063 0,05326464 ! regulation of behavior GO:0050795 45 25 0,000 0,03827063 0,05323342 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,03827063 0,05320224 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,03827063 0,05317109 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,03827063 0,05313997 ! negative regulation of phosphorylation GO:0042326 46 25 0,000 0,03827063 0,0531089 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03827063 0,05307786 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,03827063 0,05304685 ! leukocyte homeostasis GO:0001776 40 25 0,000 0,03827063 0,05301589 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,03827063 0,05298496 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,03827063 0,05295406 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,03827063 0,0529232 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,03827063 0,05289238 ! regulation of amine transport GO:0051952 44 25 0,000 0,03827063 0,05286159 ! liver development GO:0001889 44 25 0,000 0,03827063 0,05283084 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,0397716 0,05487093 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,0397716 0,05483905 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,0397716 0,0548072 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,0397716 0,05477539 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,0397716 0,05474362 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,0397716 0,05471188 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,0397716 0,05468018 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,0397716 0,05464852 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,0397716 0,0546169 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,0397716 0,05458531 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,0397716 0,05455376 ! sperm motility GO:0030317 31 26 0,000 0,0397716 0,05452224 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,0397716 0,05449076 ! male gonad development GO:0008584 39 26 0,000 0,0397716 0,05445932 ! neural crest cell development GO:0014032 44 26 0,000 0,0397716 0,05442791 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,0397716 0,05439654 ! cell fate determination GO:0001709 54 26 0,000 0,0397716 0,05436521 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,0397716 0,05433391 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,0397716 0,05430265 ! detection of visible light GO:0009584 33 26 0,000 0,0397716 0,05427142 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,0397716 0,05424023 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,0397716 0,05420907 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,0397716 0,05417796 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,0397716 0,05414687 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,04127029 0,05615505 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,04127029 0,05612287 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,04127029 0,05609072 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,04127029 0,05605862 ! membrane docking GO:0022406 40 27 0,000 0,04127029 0,05602655 ! circadian rhythm GO:0007623 44 27 0,000 0,04127029 0,05599451 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,04127029 0,05596252 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,04127029 0,05593056 ! autophagy GO:0006914 36 27 0,000 0,04127029 0,05589863 ! myofibril assembly GO:0030239 40 27 0,000 0,04127029 0,05586674 GO:0055002|striated muscle cell development, ! negative regulation of phosphorus metabolic process GO:0010563 51 27 0,000 0,04127029 0,05583489 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,04127029 0,05580308 ! peptide transport GO:0015833 46 27 0,000 0,04127029 0,0557713 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,04127029 0,05573956 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,04127029 0,05570785 ! negative regulation of cell development GO:0010721 67 27 0,000 0,04127029 0,05567618 GO:0050768|negative regulation of neurogenesis, ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,04127029 0,05564455 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,04127029 0,05561295 ! detection of light stimulus GO:0009583 35 27 0,000 0,04127029 0,05558139 ! glutathione metabolic process GO:0006749 35 27 0,000 0,04127029 0,05554986 ! lipid oxidation GO:0034440 39 27 0,000 0,04127029 0,05551837 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,04127029 0,05548691 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,04127029 0,05545549 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,04127029 0,05542411 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,04276672 0,05740126 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,04276672 0,05736881 ! translational initiation GO:0006413 48 28 0,000 0,04276672 0,0573364 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,04276672 0,05730403 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,04276672 0,05727169 ! regulation of pH GO:0006885 40 28 0,000 0,04276672 0,05723939 ! negative regulation of protein modification process GO:0031400 56 28 0,000 0,04276672 0,05720712 ! catechol metabolic process GO:0009712 46 28 0,000 0,04276672 0,05717489 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,04276672 0,0571427 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,04276672 0,05711054 ! iron ion homeostasis GO:0055072 49 28 0,000 0,04276672 0,05707842 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,04276672 0,05704634 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,04276672 0,05701429 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,04276672 0,05698228 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,04276672 0,0569503 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,04276672 0,05691836 ! gene silencing GO:0016458 47 28 0,000 0,04276672 0,05688645 ! regulation of coagulation GO:0050818 42 28 0,000 0,04276672 0,05685458 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,04426089 0,05880801 ! phenol metabolic process GO:0018958 47 29 0,000 0,04426089 0,0587751 ! positive regulation of cell adhesion GO:0045785 54 29 0,000 0,04426089 0,05874223 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,04426089 0,05870939 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,04426089 0,05867659 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,04426089 0,05864383 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,04426089 0,05861111 ! cholesterol transport GO:0030301 48 29 0,000 0,04426089 0,05857842 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,04426089 0,05854576 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,04426089 0,05851315 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,04426089 0,05848057 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,04426089 0,05844802 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,04426089 0,05841552 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,04426089 0,05838305 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,04426089 0,05835061 ! response to ionizing radiation GO:0010212 55 29 0,000 0,04426089 0,05831821 ! muscle cell development GO:0055001 42 29 0,000 0,04426089 0,05828585 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,04426089 0,05825352 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,04426089 0,05822123 ! mesoderm formation GO:0001707 52 29 0,000 0,04426089 0,05818898 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,04426089 0,05815676 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,04426089 0,05812457 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,04426089 0,05809242 ! ensheathment of neurons GO:0007272 48 29 0,000 0,04426089 0,05806031 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,04426089 0,05802823 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,04426089 0,05799619 ! neural tube formation GO:0001841 46 29 0,000 0,04426089 0,05796418 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,04575281 0,05988495 ! organic anion transport GO:0015711 50 30 0,000 0,04575281 0,05985194 ! cell junction assembly GO:0034329 65 30 0,000 0,04575281 0,05981896 ! acute-phase response GO:0006953 49 30 0,000 0,04575281 0,05978602 ! segmentation GO:0035282 43 30 0,000 0,04575281 0,05975312 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,04575281 0,05972025 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,04575281 0,05968742 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,04575281 0,05965462 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,04575281 0,05962186 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,04575281 0,05958914 ! ceramide metabolic process GO:0006672 47 30 0,000 0,04575281 0,05955645 ! formation of primary germ layer GO:0001704 54 30 0,000 0,04575281 0,0595238 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,04575281 0,05949118 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,04575281 0,0594586 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,04575281 0,05942606 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,04575281 0,05939355 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,04575281 0,05936108 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,04575281 0,05932864 ! response to heat GO:0009408 43 30 0,000 0,04575281 0,05929624 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,04575281 0,05926387 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,04724247 0,06116005 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,04724247 0,0611267 ! post-embryonic development GO:0009791 50 31 0,000 0,04724247 0,06109339 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,04724247 0,06106012 ! regulation of innate immune response GO:0045088 42 31 0,000 0,04724247 0,06102688 ! ovulation cycle process GO:0022602 46 31 0,000 0,04724247 0,06099367 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,04724247 0,06096051 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,04724247 0,06092738 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,04724247 0,06089428 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,04724247 0,06086122 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,04724247 0,0608282 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,04724247 0,06079521 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,04724247 0,06076226 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,04724247 0,06072935 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,04724247 0,06069647 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,04724247 0,06066362 ! tissue homeostasis GO:0001894 45 31 0,000 0,04724247 0,06063081 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,04872988 0,06250594 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,04872988 0,06247218 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,04872988 0,06243844 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,04872988 0,06240475 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,04872988 0,06237109 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,04872988 0,06233746 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,04872988 0,06230388 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,04872988 0,06227033 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,04872988 0,06223681 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,04872988 0,06220333 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,04872988 0,06216989 ! telencephalon development GO:0021537 59 32 0,000 0,04872988 0,06213648 ! ovulation cycle GO:0042698 48 32 0,000 0,04872988 0,06210311 ! cofactor catabolic process GO:0051187 52 32 0,000 0,04872988 0,06206978 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,04872988 0,06203648 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,04872988 0,06200322 ! placenta development GO:0001890 45 32 0,000 0,04872988 0,06196999 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,04872988 0,06193679 ! vesicle localization GO:0051648 50 32 0,000 0,04872988 0,06190364 ! regulation of muscle development GO:0048634 52 33 0,000 0,05021504 0,06375617 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,05021504 0,06372208 ! negative regulation of secretion GO:0051048 53 33 0,000 0,05021504 0,06368802 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,05021504 0,063654 ! glial cell differentiation GO:0010001 65 33 0,000 0,05021504 0,06362001 ! sister chromatid segregation GO:0000819 48 33 0,000 0,05021504 0,06358606 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,05021504 0,06355215 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,05021504 0,06351828 ! spindle organization GO:0007051 39 33 0,000 0,05021504 0,06348444 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,05021504 0,06345063 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,05021504 0,06341686 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,05021504 0,06338313 ! protein targeting to membrane GO:0006612 63 33 0,000 0,05021504 0,06334943 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,05021504 0,06331577 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,05021504 0,06328215 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,05021504 0,06324856 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,05021504 0,06321501 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,05021504 0,06318149 ! cytokine production GO:0001816 49 33 0,000 0,05021504 0,063148 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,05021504 0,06311456 ! RNA modification GO:0009451 43 33 0,000 0,05021504 0,06308115 ! regulation of B cell activation GO:0050864 55 33 0,000 0,05021504 0,06304777 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,05021504 0,06301443 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,05169796 0,06484104 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,05169796 0,06480679 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,05169796 0,06477257 ! actomyosin structure organization GO:0031032 48 34 0,000 0,05169796 0,06473839 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,05169796 0,06470425 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,05169796 0,06467014 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,05169796 0,06463606 ! positive regulation of cell development GO:0010720 58 34 0,000 0,05169796 0,06460203 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,05169796 0,06456803 ! cell fate specification GO:0001708 49 34 0,000 0,05169796 0,06453406 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 0,000 0,05169796 0,06450013 ! peripheral nervous system development GO:0007422 58 34 0,000 0,05169796 0,06446624 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,05169796 0,06443238 ! adult locomotory behavior GO:0008344 54 34 0,000 0,05169796 0,06439856 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,05169796 0,06436477 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,05317863 0,06617352 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,05317863 0,06613883 ! collagen metabolic process GO:0032963 47 35 0,000 0,05317863 0,06610419 ! cell junction organization GO:0034330 72 35 0,000 0,05317863 0,06606958 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,05317863 0,06603501 ! metanephros development GO:0001656 61 35 0,000 0,05317863 0,06600047 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,05317863 0,06596597 ! female gonad development GO:0008585 55 35 0,000 0,05317863 0,0659315 ! lipid homeostasis GO:0055088 63 35 0,000 0,05317863 0,06589707 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,05317863 0,06586268 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05317863 0,06582832 ! negative regulation of hydrolase activity GO:0051346 56 35 0,000 0,05317863 0,065794 ! hindbrain development GO:0030902 56 35 0,000 0,05317863 0,06575972 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,05317863 0,06572547 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,05317863 0,06569125 ! cytokinesis GO:0000910 57 35 0,000 0,05317863 0,06565707 ! embryonic organ development GO:0048568 53 35 0,000 0,05317863 0,06562293 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,05317863 0,06558882 ! protein homooligomerization GO:0051260 59 35 0,000 0,05317863 0,06555475 ! meiosis I GO:0007127 61 36 0,000 0,05465707 0,06734228 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,05465707 0,06730733 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,05465707 0,06727242 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,05465707 0,06723755 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,05465707 0,06720271 ! spliceosome assembly GO:0000245 65 36 0,000 0,05465707 0,06716791 ! mismatch repair GO:0006298 42 36 0,000 0,05465707 0,06713314 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,05465707 0,06709841 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,05465707 0,06706372 ! regulation of proteolysis GO:0030162 53 36 0,000 0,05465707 0,06702906 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,05465707 0,06699444 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,05465707 0,06695985 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,05465707 0,0669253 ! eye morphogenesis GO:0048592 64 36 0,000 0,05465707 0,06689079 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,05465707 0,06685631 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,05613328 0,06862662 ! mammary gland development GO:0030879 73 37 0,000 0,05613328 0,06859128 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,05613328 0,06855598 ! ear morphogenesis GO:0042471 50 37 0,000 0,05613328 0,06852071 ! odontogenesis GO:0042476 60 37 0,000 0,05613328 0,06848549 ! negative regulation of binding GO:0051100 59 37 0,000 0,05613328 0,06845029 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,05613328 0,06841514 ! tissue remodeling GO:0048771 65 37 0,000 0,05613328 0,06838001 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,05613328 0,06834493 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 58 37 0,000 0,05613328 0,06830988 ! keratinocyte differentiation GO:0030216 55 37 0,000 0,05613328 0,06827487 ! natural killer cell activation GO:0030101 45 37 0,000 0,05613328 0,06823989 ! polyol metabolic process GO:0019751 47 37 0,000 0,05613328 0,06820495 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,05613328 0,06817005 ! glucan metabolic process GO:0044042 54 37 0,000 0,05613328 0,06813518 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,05760725 0,06988855 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,05760725 0,06985284 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,05760725 0,06981717 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,05760725 0,06978153 ! feeding behavior GO:0007631 50 38 0,000 0,05760725 0,06974592 ! organic ether metabolic process GO:0018904 51 38 0,000 0,05760725 0,06971036 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,05760725 0,06967483 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,05760725 0,06963933 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,05760725 0,06960387 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,05760725 0,06956845 ! ion transmembrane transport GO:0034220 58 38 0,000 0,05760725 0,06953307 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,05760725 0,06949772 ! neuron migration GO:0001764 59 38 0,000 0,05760725 0,0694624 ! maintenance of protein location GO:0045185 72 38 0,000 0,05760725 0,06942713 ! pigment metabolic process GO:0042440 66 38 0,000 0,05760725 0,06939188 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,05760725 0,06935668 ! mRNA catabolic process GO:0006402 58 39 0,000 0,059079 0,07109253 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,059079 0,0710565 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,059079 0,0710205 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,059079 0,07098454 ! neural tube development GO:0021915 58 39 0,000 0,059079 0,07094862 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,059079 0,07091273 ! regulation of protein stability GO:0031647 58 39 0,000 0,059079 0,07087688 ! female gamete generation GO:0007292 50 39 0,000 0,059079 0,07084106 ! aerobic respiration GO:0009060 56 39 0,000 0,059079 0,07080529 ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,059079 0,07076954 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,06054852 0,07249326 ! Notch signaling pathway GO:0007219 64 40 0,000 0,06054852 0,0724567 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,06054852 0,07242018 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,06054852 0,0723837 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,06054852 0,07234725 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,06054852 0,07231084 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,06054852 0,07227447 ! phagocytosis GO:0006909 65 40 0,000 0,06054852 0,07223813 ! mesenchymal cell development GO:0014031 70 40 0,000 0,06054852 0,07220183 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,06054852 0,07216557 ! B cell differentiation GO:0030183 70 40 0,000 0,06054852 0,07212934 ! pigmentation GO:0043473 81 40 0,000 0,06054852 0,07209315 ! developmental growth GO:0048589 70 40 0,000 0,06054852 0,07205699 ! synapse organization GO:0050808 61 40 0,000 0,06054852 0,07202087 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,06201582 0,07372923 ! RNA export from nucleus GO:0006405 57 41 0,000 0,06201582 0,07369231 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,06201582 0,07365543 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,06201582 0,07361858 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,06201582 0,07358177 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,06201582 0,073545 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,06201582 0,07350827 ! cell growth GO:0016049 71 41 0,000 0,06201582 0,07347157 ! maintenance of location in cell GO:0051651 77 41 0,000 0,06201582 0,0734349 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,06348091 0,07513226 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,06348091 0,07509481 ! learning GO:0007612 75 42 0,000 0,06348091 0,07505739 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,06348091 0,07502002 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,06348091 0,07498267 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,06348091 0,07494537 ! gliogenesis GO:0042063 85 42 0,000 0,06348091 0,0749081 ! endosome transport GO:0016197 74 42 0,000 0,06348091 0,07487087 ! induction of apoptosis by intracellular signals GO:0008629 78 42 0,000 0,06348091 0,07483368 ! male sex differentiation GO:0046661 62 42 0,000 0,06348091 0,07479652 ! double-strand break repair GO:0006302 75 42 0,000 0,06348091 0,0747594 ! epidermal cell differentiation GO:0009913 61 42 0,000 0,06348091 0,07472232 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,06348091 0,07468527 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,06348091 0,07464826 ! mitochondrial transport GO:0006839 66 43 0,000 0,06494378 0,07633065 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,06494378 0,07629286 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,06494378 0,07625511 ! regulation of tube size GO:0035150 69 43 0,000 0,06494378 0,0762174 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,06494378 0,07617972 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,06494378 0,07614208 ! T cell differentiation GO:0030217 78 43 0,000 0,06494378 0,07610448 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,06494378 0,07606692 ! amino acid activation GO:0043038 61 43 0,000 0,06494378 0,07602939 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,06494378 0,0759919 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,06640443 0,07766275 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,06640443 0,07762449 ! cellular component disassembly GO:0022411 66 44 0,000 0,06640443 0,07758627 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,06640443 0,07754809 ! peptide metabolic process GO:0006518 64 44 0,000 0,06640443 0,07750995 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,06640443 0,07747184 ! inner ear development GO:0048839 66 44 0,000 0,06640443 0,07743377 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,06640443 0,07739574 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,06640443 0,07735774 ! chromatin remodeling GO:0006338 73 44 0,000 0,06640443 0,07731978 ! biopolymer methylation GO:0043414 67 44 0,000 0,06640443 0,07728186 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,06640443 0,07724398 ! JNK cascade GO:0007254 66 44 0,000 0,06640443 0,07720613 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,06640443 0,07716832 ! regulation of cell shape GO:0008360 83 44 0,000 0,06640443 0,07713055 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,06786288 0,07878602 ! positive regulation of binding GO:0051099 67 45 0,000 0,06786288 0,07874749 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,06786288 0,078709 ! regulation of ion transport GO:0043269 60 45 0,000 0,06786288 0,07867055 ! glucose transport GO:0015758 60 45 0,000 0,06786288 0,07863214 ! neuromuscular process GO:0050905 89 45 0,000 0,06786288 0,07859376 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,06786288 0,07855542 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,06786288 0,07851712 ! response to insulin stimulus GO:0032868 71 45 0,000 0,06786288 0,07847886 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,06931913 0,08012386 ! regulation of translational initiation GO:0006446 70 46 0,000 0,06931913 0,08008485 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,06931913 0,08004588 ! regulation of action potential GO:0001508 80 46 0,000 0,06931913 0,08000695 ! hexose transport GO:0008645 62 46 0,000 0,06931913 0,07996805 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,06931913 0,0799292 ! excretion GO:0007588 72 46 0,000 0,06931913 0,07989038 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,06931913 0,07985159 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,06931913 0,07981285 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,06931913 0,07977414 ! positive regulation of defense response GO:0031349 70 47 0,000 0,07077317 0,08140801 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,07077317 0,08136857 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,07077317 0,08132917 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,07077317 0,0812898 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,07077317 0,08125047 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,07077317 0,08121118 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,07222501 0,0828371 ! viral infectious cycle GO:0019058 80 48 0,000 0,07222501 0,08279708 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,07222501 0,0827571 ! leukocyte migration GO:0050900 76 48 0,000 0,07222501 0,08271716 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,07222501 0,08267726 ! striated muscle contraction GO:0006941 78 48 0,000 0,07222501 0,08263739 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,07222501 0,08259757 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,07222501 0,08255778 ! tRNA processing GO:0008033 56 48 0,000 0,07222501 0,08251803 ! cell maturation GO:0048469 69 48 0,000 0,07222501 0,08247832 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,07222501 0,08243865 ! vesicle organization GO:0016050 87 48 0,000 0,07222501 0,08239902 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,07222501 0,08235942 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,07367466 0,08397213 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,07367466 0,08393181 ! glycolysis GO:0006096 63 49 0,000 0,07367466 0,08389154 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,07367466 0,0838513 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,07367466 0,08381111 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,07367466 0,08377095 ! response to temperature stimulus GO:0009266 66 49 0,000 0,07367466 0,08373083 ! endocrine system development GO:0035270 86 49 0,000 0,07367466 0,08369075 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,07367466 0,0836507 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,07367466 0,0836107 ! gastrulation GO:0007369 80 49 0,000 0,07367466 0,08357073 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,07367466 0,0835308 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,07367466 0,08349091 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,07367466 0,08345106 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,07367466 0,08341124 ! methylation GO:0032259 74 49 0,000 0,07367466 0,08337147 ! cell redox homeostasis GO:0045454 72 50 0,000 0,07512212 0,08496891 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,07512212 0,08492843 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,07512212 0,08488799 ! histone modification GO:0016570 81 50 0,000 0,07512212 0,08484759 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,07512212 0,08480722 ! RNA catabolic process GO:0006401 77 51 0,000 0,07656738 0,08639772 ! chloride transport GO:0006821 78 51 0,000 0,07656738 0,08635665 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,07656738 0,08631563 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,07656738 0,08627464 ! regulation of ossification GO:0030278 82 51 0,000 0,07656738 0,0862337 ! heart morphogenesis GO:0003007 71 51 0,000 0,07656738 0,08619279 ! RNA elongation GO:0006354 67 51 0,000 0,07656738 0,08615192 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,07656738 0,08611109 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,07801047 0,08769248 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,07801047 0,08765096 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,07801047 0,08760948 ! regulation of DNA replication GO:0006275 88 52 0,000 0,07801047 0,08756804 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,07801047 0,08752664 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,07801047 0,08748527 ! covalent chromatin modification GO:0016569 90 52 0,000 0,07801047 0,08744395 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,07801047 0,08740266 ! proton transport GO:0015992 78 52 0,000 0,07801047 0,08736141 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,07801047 0,0873202 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,07801047 0,08727904 ! transition metal ion transport GO:0000041 88 53 0,000 0,07945136 0,08884924 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,07945136 0,08880739 ! muscle fiber development GO:0048747 80 53 0,000 0,07945136 0,08876558 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,07945136 0,08872381 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,07945136 0,08868207 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,07945136 0,08864038 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,07945136 0,08859873 ! regulation of endocytosis GO:0030100 71 53 0,000 0,07945136 0,08855711 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,07945136 0,08851553 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,07945136 0,088474 ! maintenance of location GO:0051235 94 53 0,000 0,07945136 0,0884325 ! hydrogen transport GO:0006818 81 54 0,000 0,08089008 0,08999164 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,08089008 0,08994947 ! regulation of mitosis GO:0007088 91 54 0,000 0,08089008 0,08990734 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,08089008 0,08986525 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,08089008 0,0898232 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,08089008 0,08978118 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,08089008 0,08973921 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,08089008 0,08969728 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,08089008 0,08965538 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,08089008 0,08961352 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,08089008 0,08957171 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,08089008 0,08952993 ! establishment of organelle localization GO:0051656 91 54 0,000 0,08089008 0,08948819 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,08232663 0,09103499 ! ear development GO:0043583 83 55 0,000 0,08232663 0,09099259 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,08232663 0,09095023 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,08232663 0,09090791 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,08232663 0,09086562 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,08232663 0,09082338 ! regulation of actin filament length GO:0030832 88 56 0,000 0,083761 0,09236285 ! positive regulation of secretion GO:0051047 83 56 0,000 0,083761 0,09231995 ! DNA catabolic process GO:0006308 71 56 0,000 0,083761 0,09227709 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,083761 0,09223427 ! adult behavior GO:0030534 90 56 0,000 0,083761 0,09219149 ! cartilage development GO:0051216 84 56 0,000 0,083761 0,09214875 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,0851932 0,09368094 ! mesoderm development GO:0007498 84 57 0,000 0,0851932 0,09363755 ! aging GO:0007568 91 57 0,000 0,0851932 0,0935942 ! nuclear export GO:0051168 85 57 0,000 0,0851932 0,09355089 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,0851932 0,09350761 ! single fertilization GO:0007338 67 57 0,000 0,0851932 0,09346438 ! regulation of cellular component size GO:0032535 90 58 0,000 0,08662323 0,09498934 ! lipid modification GO:0030258 82 58 0,000 0,08662323 0,09494547 ! positive regulation of growth GO:0045927 78 58 0,000 0,08662323 0,09490163 ! DNA damage response, signal transduction GO:0042770 105 58 0,000 0,08662323 0,09485784 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,08662323 0,09481408 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,0880511 0,09633254 ! viral reproductive process GO:0022415 99 59 0,000 0,0880511 0,09628814 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,0880511 0,09624379 ! chromosome segregation GO:0007059 93 59 0,000 0,0880511 0,09619948 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,0880511 0,09615521 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,0880511 0,09611098 ! cell projection assembly GO:0030031 90 59 0,000 0,0880511 0,09606679 ! glucose catabolic process GO:0006007 78 60 0,000 0,08947682 0,09757743 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,08947682 0,09753261 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,08947682 0,09748783 ! response to peptide hormone stimulus GO:0043434 97 60 0,000 0,08947682 0,09744309 ! kidney development GO:0001822 101 60 0,000 0,08947682 0,09739839 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,08947682 0,09735373 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,09090037 0,09885728 ! carbohydrate transport GO:0008643 83 61 0,000 0,09090037 0,09881199 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,09090037 0,09876675 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,09232177 0,10026524 ! amino acid transport GO:0006865 97 62 0,000 0,09232177 0,10021938 ! negative regulation of protein kinase activity GO:0006469 110 62 0,000 0,09232177 0,10017355 ! activation of MAPK activity GO:0000187 95 62 0,000 0,09232177 0,10012777 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,09232177 0,10008203 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,09232177 0,10003633 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,09232177 0,09999067 ! detection of external stimulus GO:0009581 78 62 0,000 0,09232177 0,09994505 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,09232177 0,09989948 ! secondary metabolic process GO:0019748 95 62 0,000 0,09232177 0,09985395 ! gonad development GO:0008406 91 62 0,000 0,09232177 0,09980845 ! exocytosis GO:0006887 91 63 0,000 0,09374102 0,10129665 ! negative regulation of kinase activity GO:0033673 112 63 0,000 0,09374102 0,10125054 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,09374102 0,10120447 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,09374102 0,10115845 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,09374102 0,10111247 ! regulation of heart contraction GO:0008016 104 63 0,000 0,09374102 0,10106653 ! developmental maturation GO:0021700 90 63 0,000 0,09374102 0,10102063 ! actin filament organization GO:0007015 107 64 0,000 0,09515812 0,10250123 ! fertilization GO:0009566 79 64 0,000 0,09515812 0,10245473 ! viral reproduction GO:0016032 104 64 0,000 0,09515812 0,10240826 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,09515812 0,10236184 ! amine catabolic process GO:0009310 100 65 0,000 0,09657307 0,10383684 ! negative regulation of cell growth GO:0030308 123 65 0,000 0,09657307 0,10378981 ! camera-type eye development GO:0043010 103 65 0,000 0,09657307 0,10374283 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,09657307 0,10369589 ! regulation of lipase activity GO:0060191 117 65 0,000 0,09657307 0,10364899 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,09657307 0,10360213 ! organelle localization GO:0051640 105 65 0,000 0,09657307 0,10355531 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,09798589 0,10502282 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,09798589 0,1049754 ! sensory perception of smell GO:0007608 81 66 0,000 0,09798589 0,10492803 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,09798589 0,1048807 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,09798589 0,10483342 ! lung development GO:0030324 112 66 0,000 0,09798589 0,10478617 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,09798589 0,10473897 ! B cell activation GO:0042113 119 66 0,000 0,09798589 0,10469181 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,09798589 0,1046447 ! negative regulation of transferase activity GO:0051348 117 66 0,000 0,09798589 0,10459762 ! protein oligomerization GO:0051259 109 66 0,000 0,09798589 0,10455059 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,09939657 0,10600811 ! negative regulation of cell size GO:0045792 125 67 0,000 0,09939657 0,10596049 ! neurotransmitter transport GO:0006836 92 67 0,000 0,09939657 0,10591291 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,09939657 0,10586537 ! appendage morphogenesis GO:0035107 103 67 0,000 0,09939657 0,10581788 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,09939657 0,10577043 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,09939657 0,10572302 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! meiosis GO:0007126 110 68 0,000 0,10080511 0,10717317 GO:0051327|M phase of meiotic cell cycle, ! regulation of caspase activity GO:0043281 104 68 0,000 0,10080511 0,10712518 ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,10080511 0,10707723 ! defense response to bacterium GO:0042742 79 68 0,000 0,10080511 0,10702932 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,10080511 0,10698145 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,10080511 0,10693363 ! activation of immune response GO:0002253 93 68 0,000 0,10080511 0,10688585 ! appendage development GO:0048736 108 69 0,000 0,10221152 0,10832869 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,10221152 0,10828033 ! urogenital system development GO:0001655 114 69 0,000 0,10221152 0,10823201 ! meiotic cell cycle GO:0051321 111 69 0,000 0,10221152 0,10818373 ! regulation of endopeptidase activity GO:0052548 106 70 0,000 0,1036158 0,10962117 ! hexose catabolic process GO:0019320 95 70 0,000 0,1036158 0,10957232 ! adaptive immune response GO:0002250 102 70 0,000 0,1036158 0,10952352 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,10501795 0,11095619 ! cell-matrix adhesion GO:0007160 133 71 0,000 0,10501795 0,11090681 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,10501795 0,11085748 ! axon guidance GO:0007411 116 71 0,000 0,10501795 0,11080818 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,10501795 0,11075894 ! regulation of actin cytoskeleton organization GO:0032956 120 72 0,000 0,10641799 0,11218564 ! response to drug GO:0042493 115 72 0,000 0,10641799 0,11213583 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,10641799 0,11208606 ! homeostasis of number of cells GO:0048872 109 72 0,000 0,10641799 0,11203633 ! respiratory system development GO:0060541 123 72 0,000 0,10641799 0,11198664 ! rhythmic process GO:0048511 113 72 0,000 0,10641799 0,111937 ! regulation of immune effector process GO:0002697 121 72 0,000 0,10641799 0,11188741 ! learning or memory GO:0007611 132 73 0,000 0,1078159 0,11330697 ! humoral immune response GO:0006959 93 73 0,000 0,1078159 0,11325681 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,1078159 0,11320669 ! acute inflammatory response GO:0002526 107 74 0,000 0,1092117 0,11462156 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,1092117 0,11457089 ! regulation of actin filament-based process GO:0032970 122 74 0,000 0,1092117 0,11452026 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,1092117 0,11446968 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,1092117 0,11441914 ! regulation of Rho protein signal transduction GO:0035023 126 74 0,000 0,1092117 0,11436865 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,1092117 0,1143182 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,11060538 0,115726 ! regulation of peptidase activity GO:0052547 113 75 0,000 0,11060538 0,115675 ! inorganic anion transport GO:0015698 109 75 0,000 0,11060538 0,11562404 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,11060538 0,11557312 ! regulation of catabolic process GO:0009894 114 75 0,000 0,11060538 0,11552226 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,11199695 0,11692423 ! phosphoinositide-mediated signaling GO:0048015 122 76 0,000 0,11199695 0,11687281 ! cell-substrate adhesion GO:0031589 141 76 0,000 0,11199695 0,11682144 ! regulation of Ras GTPase activity GO:0032318 125 76 0,000 0,11199695 0,11677011 ! negative regulation of transport GO:0051051 122 77 0,000 0,11338642 0,11816687 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,11338642 0,118115 ! response to nutrient GO:0007584 114 77 0,000 0,11338642 0,11806317 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,11338642 0,11801139 ! regulation of blood pressure GO:0008217 119 78 0,000 0,11477378 0,11940297 ! muscle cell differentiation GO:0042692 117 78 0,000 0,11477378 0,11935065 ! mitochondrion organization GO:0007005 127 78 0,000 0,11477378 0,11929837 ! negative regulation of growth GO:0045926 140 78 0,000 0,11477378 0,11924614 ! amine transport GO:0015837 115 78 0,000 0,11477378 0,11919395 ! antigen processing and presentation GO:0019882 114 78 0,000 0,11477378 0,11914181 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,11615904 0,12052707 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,1175422 0,12190894 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,1175422 0,12185568 ! regulation of DNA binding GO:0051101 130 80 0,000 0,1175422 0,12180247 ! tube morphogenesis GO:0035239 140 80 0,000 0,1175422 0,1217493 ! eye development GO:0001654 130 80 0,000 0,1175422 0,12169618 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,1175422 0,12164311 ! protein ubiquitination GO:0016567 135 80 0,000 0,1175422 0,12159008 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,1175422 0,1215371 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,1175422 0,12148417 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,1175422 0,12143128 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,1175422 0,12137844 ! blood coagulation GO:0007596 129 81 0,000 0,11892327 0,12275116 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,11892327 0,12269779 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,11892327 0,12264447 ! response to hypoxia GO:0001666 155 81 0,000 0,11892327 0,12259119 ! regulation of protein transport GO:0051223 123 81 0,000 0,11892327 0,12253796 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,12030225 0,12390505 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,12030225 0,12385129 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,12030225 0,12379759 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,12030225 0,12374392 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,12167913 0,12510597 ! response to oxygen levels GO:0070482 160 83 0,000 0,12167913 0,12505179 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,12167913 0,12499766 ! regulation of lyase activity GO:0051339 147 83 0,000 0,12167913 0,12494357 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,12167913 0,12488953 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,12305394 0,126246 ! digestion GO:0007586 111 84 0,000 0,12305394 0,12619144 ! regulation of neurological system process GO:0031644 133 84 0,000 0,12305394 0,12613693 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,12305394 0,12608247 ! cellular respiration GO:0045333 119 85 0,000 0,12442665 0,12743395 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,12442665 0,12737897 ! T cell activation GO:0042110 154 85 0,000 0,12442665 0,12732404 ! sex differentiation GO:0007548 126 85 0,000 0,12442665 0,12726916 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,12442665 0,12721433 ! alcohol catabolic process GO:0046164 119 86 0,000 0,12579729 0,12856028 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,12579729 0,12850494 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,12716586 0,12984707 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,12716586 0,12979122 ! regulation of defense response GO:0031347 135 87 0,000 0,12716586 0,12973542 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,12716586 0,12967966 ! tRNA metabolic process GO:0006399 110 87 0,000 0,12716586 0,12962396 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,12716586 0,1295683 ! gland development GO:0048732 170 87 0,000 0,12716586 0,1295127 ! vitamin metabolic process GO:0006766 117 87 0,000 0,12716586 0,12945713 ! regulation of membrane potential GO:0042391 144 88 0,000 0,12853235 0,13079214 ! nucleosome assembly GO:0006334 113 89 0,000 0,12989677 0,13212389 GO:0031497|chromatin assembly, ! microtubule cytoskeleton organization GO:0000226 133 90 0,000 0,13125912 0,13345239 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,13125912 0,13339524 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,13125912 0,13333814 GO:0060538|skeletal muscle organ development, ! regulation of GTPase activity GO:0043087 149 90 0,000 0,13125912 0,13328108 ! regulation of protein localization GO:0032880 141 90 0,000 0,13125912 0,13322407 ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,1326194 0,13454718 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,1326194 0,13448968 ! sterol metabolic process GO:0016125 136 92 0,000 0,13397763 0,13580902 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,1353338 0,13712515 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cell cycle arrest GO:0007050 171 93 0,000 0,1353338 0,13706663 ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,1353338 0,13700815 ! rRNA processing GO:0006364 124 93 0,000 0,1353338 0,13694972 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,1353338 0,13689135 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,1353338 0,13683302 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,1353338 0,13677475 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,1353338 0,13671652 ! leukocyte differentiation GO:0002521 165 94 0,000 0,13668791 0,13802571 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,13668791 0,137967 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,13668791 0,13790834 ! rRNA metabolic process GO:0016072 125 94 0,000 0,13668791 0,13784973 ! regulation of cell adhesion GO:0030155 187 94 0,000 0,13668791 0,13779117 ! hormone metabolic process GO:0042445 135 94 0,000 0,13668791 0,13773266 ! protein processing GO:0016485 127 94 0,000 0,13668791 0,1376742 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,13803997 0,13897703 ! ATP metabolic process GO:0046034 150 96 0,000 0,13938998 0,14027669 ! nucleosome organization GO:0034728 126 96 0,000 0,13938998 0,14021722 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,13938998 0,14015781 ! female pregnancy GO:0007565 148 96 0,000 0,13938998 0,14009844 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,14073795 0,14139337 ! reproductive developmental process GO:0003006 149 97 0,000 0,14073795 0,14133354 ! response to virus GO:0009615 141 98 0,000 0,14208387 0,1426248 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,14208387 0,14256449 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,14208387 0,14250423 ! regulation of binding GO:0051098 164 99 0,000 0,14342775 0,14379132 ! electron transport chain GO:0022900 135 99 0,000 0,14342775 0,14373059 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,14342775 0,14366992 ! cell fate commitment GO:0045165 165 99 0,000 0,14342775 0,1436093 ! positive regulation of immune response GO:0050778 143 99 0,000 0,14342775 0,14354873 ! sulfur metabolic process GO:0006790 136 99 0,000 0,14342775 0,14348821 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,14476959 0,14476959