pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/333-4-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! NLS-bearing substrate import into nucleus GO:0006607 7 7 2,000 1,061E-07 1,955E-04 ! regulation of DNA recombination GO:0000018 13 13 2,000 8,623E-07 7,946E-04 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 1,183E-05 7,27E-03 ! nucleoside metabolic process GO:0009116 31 31 2,000 1,334E-05 6,147E-03 ! mRNA stabilization GO:0048255 5 5 1,000 2,318E-05 8,545E-03 GO:0043489|RNA stabilization, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 1,000 2,318E-05 7,121E-03 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 1,000 3,474E-05 9,147E-03 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! protein import into nucleus GO:0006606 44 44 2,000 3,886E-05 8,953E-03 ! nuclear import GO:0051170 45 45 2,000 4,16E-05 8,519E-03 ! regulation of mRNA stability GO:0043488 7 7 1,000 4,86E-05 8,956E-03 ! protein localization in nucleus GO:0034504 48 48 2,000 5,057E-05 8,473E-03 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 5,721E-05 8,787E-03 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 1,000 6,474E-05 9,178E-03 ! regulation of RNA stability GO:0043487 8 8 1,000 6,474E-05 8,522E-03 ! RNA polyadenylation GO:0043631 9 9 1,000 8,316E-05 0,01021792 GO:0006378|mRNA polyadenylation, ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 1,000 8,316E-05 9,579E-03 ! protein localization in organelle GO:0033365 59 59 2,000 9,415E-05 0,01020651 ! purine ribonucleoside metabolic process GO:0046128 10 10 1,000 1,039E-04 0,01063438 GO:0042278|purine nucleoside metabolic process, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 1,000 1,039E-04 0,01007467 ! mRNA 3'-end processing GO:0031124 10 10 1,000 1,039E-04 9,571E-03 ! protein import GO:0017038 62 62 2,000 1,092E-04 9,587E-03 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 1,000 1,268E-04 0,0106251 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 1,000 1,268E-04 0,01016314 ! RNA 3'-end processing GO:0031123 11 11 1,000 1,268E-04 9,74E-03 ! regulation of translation GO:0006417 69 69 2,000 1,504E-04 0,01108818 ! regulation of alpha-beta T cell activation GO:0046634 12 12 1,000 1,521E-04 0,01077915 ! spermatid differentiation GO:0048515 13 12 1,000 1,521E-04 0,01037993 GO:0007286|spermatid development, ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 1,000 1,521E-04 0,01000921 ! negative regulation of translation GO:0017148 12 12 1,000 1,521E-04 9,664E-03 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 1,000 1,796E-04 0,01103084 GO:0019692|deoxyribose phosphate metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 13 13 1,000 1,796E-04 0,010675 ! D-ribose metabolic process GO:0006014 14 14 1,000 2,093E-04 0,01205445 ! DNA modification GO:0006304 14 14 1,000 2,093E-04 0,01168916 ! nuclear transport GO:0051169 79 79 2,000 2,25E-04 0,01219817 GO:0006913|nucleocytoplasmic transport, ! deoxyribonucleotide metabolic process GO:0009262 15 15 1,000 2,413E-04 0,01270569 ! pentose metabolic process GO:0019321 16 16 1,000 2,755E-04 0,01410512 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 3,12E-04 0,01554018 ! positive regulation of T cell proliferation GO:0042102 19 19 1,000 3,916E-04 0,01899212 ! ribonucleoside metabolic process GO:0009119 19 19 1,000 3,916E-04 0,01850514 ! positive regulation of T cell differentiation GO:0045582 19 19 1,000 3,916E-04 0,01804251 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 1,000 5,276E-04 0,02371658 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! positive regulation of lymphocyte differentiation GO:0045621 22 22 1,000 5,276E-04 0,0231519 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 1,000 5,276E-04 0,02261348 ! regulation of T cell proliferation GO:0042129 25 25 1,000 6,834E-04 0,02862565 ! negative regulation of cell migration GO:0030336 26 26 1,000 7,397E-04 0,03029554 ! regulation of T cell differentiation GO:0045580 26 26 1,000 7,397E-04 0,02963694 ! germ cell development GO:0007281 27 26 1,000 7,397E-04 0,02900637 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 8,588E-04 0,03297618 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 9,217E-04 0,03466576 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! extracellular matrix organization GO:0030198 31 31 1,000 1,054E-03 0,03884147 ! negative regulation of cell motion GO:0051271 31 31 1,000 1,054E-03 0,03807988 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 1,123E-03 0,03980266 ! heterocycle catabolic process GO:0046700 36 36 1,000 1,421E-03 0,04942906 ! positive regulation of T cell activation GO:0050870 39 39 1,000 1,668E-03 0,05691217 ! forebrain development GO:0030900 43 42 1,000 1,933E-03 0,06475661 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 1,933E-03 0,06360025 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 2,12E-03 0,06853335 ! positive regulation of lymphocyte activation GO:0051251 44 44 1,000 2,12E-03 0,06735174 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 2,216E-03 0,06922929 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 2,315E-03 0,07110772 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 2,315E-03 0,06994202 ! positive regulation of ligase activity GO:0051351 47 46 1,000 2,315E-03 0,06881392 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 2,519E-03 0,07367807 ! ossification GO:0001503 50 49 1,000 2,623E-03 0,07554714 GO:0060348|bone development, ! regulation of ligase activity GO:0051340 50 49 1,000 2,623E-03 0,07438487 ! positive regulation of cell activation GO:0050867 49 49 1,000 2,623E-03 0,07325783 GO:0002696|positive regulation of leukocyte activation, ! nitrogen compound catabolic process GO:0044270 51 50 1,000 2,73E-03 0,07510571 ! transcription initiation GO:0006352 50 50 1,000 2,73E-03 0,07400121 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 2,839E-03 0,0758392 GO:0051325|interphase, ! regulation of T cell activation GO:0050863 53 53 1,000 3,063E-03 0,08065399 ! extracellular structure organization GO:0043062 56 56 1,000 3,415E-03 0,08863394 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 1,000 3,536E-03 0,09050219 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 3,911E-03 0,09873523 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 4,04E-03 0,10061486 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of lymphocyte activation GO:0051249 62 62 1,000 4,171E-03 0,10249296 ! nucleoside triphosphate metabolic process GO:0009141 66 66 1,000 4,715E-03 0,11433036 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 4,715E-03 0,11284555 ! regulation of leukocyte activation GO:0002694 69 69 1,000 5,143E-03 0,12151904 ! regulation of cell migration GO:0030334 71 71 1,000 5,438E-03 0,12686805 ! negative regulation of signal transduction GO:0009968 71 71 1,000 5,438E-03 0,1252822 ! regulation of cell activation GO:0050865 71 71 1,000 5,438E-03 0,12373551 ! negative regulation of cell communication GO:0010648 76 76 1,000 6,21E-03 0,13956906 ! regulation of locomotion GO:0040012 79 79 1,000 6,696E-03 0,14867394 ! regulation of cell motion GO:0051270 79 79 1,000 6,696E-03 0,14690401 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 7,718E-03 0,16733886 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 7,718E-03 0,16539306 ! rRNA transcription GO:0009303 5 5 0,000 7,971E-03 0,16885638 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 7,971E-03 0,16693756 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 7,971E-03 0,16506186 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 7,971E-03 0,16322784 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 7,971E-03 0,16143412 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 7,971E-03 0,15967941 ! reproductive cellular process GO:0048610 5 5 0,000 7,971E-03 0,15796242 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 7,971E-03 0,15628197 ! negative regulation of blood pressure GO:0045776 6 5 0,000 7,971E-03 0,1546369 ! prostate gland development GO:0030850 5 5 0,000 7,971E-03 0,1530261 ! metencephalon development GO:0022037 5 5 0,000 7,971E-03 0,15144851 ! water transport GO:0006833 5 5 0,000 7,971E-03 0,14990312 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 7,971E-03 0,14838894 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 7,971E-03 0,14690505 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 7,971E-03 0,14545055 ! glycerol metabolic process GO:0006071 5 5 0,000 7,971E-03 0,14402456 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 7,971E-03 0,14262627 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 7,971E-03 0,14125486 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 7,971E-03 0,13990957 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 7,971E-03 0,13858967 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 7,971E-03 0,13729444 ! filopodium assembly GO:0046847 7 5 0,000 7,971E-03 0,1360232 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 7,971E-03 0,13477528 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 7,971E-03 0,13355005 ! GTP metabolic process GO:0046039 5 5 0,000 7,971E-03 0,1323469 ! establishment of tissue polarity GO:0007164 5 5 0,000 7,971E-03 0,13116523 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 7,971E-03 0,13000447 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 7,971E-03 0,12886408 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 7,971E-03 0,12774352 ! social behavior GO:0035176 5 5 0,000 7,971E-03 0,12664229 ! macrophage chemotaxis GO:0048246 6 5 0,000 7,971E-03 0,12555987 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 7,971E-03 0,12449581 ! memory GO:0007613 5 5 0,000 7,971E-03 0,12344962 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 7,971E-03 0,12242088 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 7,971E-03 0,12140914 ! membrane hyperpolarization GO:0060081 5 5 0,000 7,971E-03 0,12041398 ! response to lipid GO:0033993 5 5 0,000 7,971E-03 0,119435 ! erythrocyte maturation GO:0043249 5 5 0,000 7,971E-03 0,11847182 ! hippocampus development GO:0021766 6 5 0,000 7,971E-03 0,11752404 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 7,971E-03 0,11659131 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 7,971E-03 0,11567327 ! middle ear morphogenesis GO:0042474 5 5 0,000 7,971E-03 0,11476957 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 7,971E-03 0,11387989 ! mechanosensory behavior GO:0007638 5 5 0,000 7,971E-03 0,11300389 ! heart looping GO:0001947 5 5 0,000 7,971E-03 0,11214126 ! negative regulation of endocytosis GO:0045806 5 5 0,000 7,971E-03 0,11129171 ! response to interferon-gamma GO:0034341 5 5 0,000 7,971E-03 0,11045493 ! pseudouridine synthesis GO:0001522 5 5 0,000 7,971E-03 0,10963064 ! endocrine pancreas development GO:0031018 5 5 0,000 7,971E-03 0,10881856 ! pH reduction GO:0045851 5 5 0,000 7,971E-03 0,10801842 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 7,971E-03 0,10722997 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 7,971E-03 0,10645294 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 7,971E-03 0,10568709 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 7,971E-03 0,10493218 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 7,971E-03 0,10418798 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 7,971E-03 0,10345426 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 7,971E-03 0,10273081 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 7,971E-03 0,1020174 ! adrenal gland development GO:0030325 5 5 0,000 7,971E-03 0,10131383 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 7,971E-03 0,1006199 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 7,971E-03 0,09993541 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 7,971E-03 0,09926017 ! astrocyte differentiation GO:0048708 5 5 0,000 7,971E-03 0,098594 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 7,971E-03 0,0979367 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 7,971E-03 0,09728811 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 7,971E-03 0,09664806 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 7,971E-03 0,09601637 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 7,971E-03 0,09539289 ! microtubule nucleation GO:0007020 5 5 0,000 7,971E-03 0,09477745 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 7,971E-03 0,09416991 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 7,971E-03 0,0935701 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 7,971E-03 0,09297788 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 7,971E-03 0,09239312 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 7,971E-03 0,09181566 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 7,971E-03 0,09124537 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 7,971E-03 0,09068213 ! response to ATP GO:0033198 5 5 0,000 7,971E-03 0,0901258 ! regulation of type I interferon production GO:0032479 5 5 0,000 7,971E-03 0,08957625 ! regulation of appetite GO:0032098 5 5 0,000 7,971E-03 0,08903337 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 7,971E-03 0,08849702 ! paraxial mesoderm development GO:0048339 5 5 0,000 7,971E-03 0,0879671 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 7,971E-03 0,08744348 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 7,971E-03 0,08692607 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 7,971E-03 0,08641474 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 7,971E-03 0,08590939 ! receptor clustering GO:0043113 5 5 0,000 7,971E-03 0,08540991 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 7,971E-03 0,08491622 ! fear response GO:0042596 5 5 0,000 7,971E-03 0,08442819 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 7,971E-03 0,08394574 ! lens development in camera-type eye GO:0002088 5 5 0,000 7,971E-03 0,08346878 ! retinol metabolic process GO:0042572 5 5 0,000 7,971E-03 0,08299721 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 7,971E-03 0,08253093 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 7,971E-03 0,08206986 ! positive regulation of exocytosis GO:0045921 6 5 0,000 7,971E-03 0,08161392 ! parturition GO:0007567 5 5 0,000 7,971E-03 0,08116301 ! cellular glucose homeostasis GO:0001678 5 5 0,000 7,971E-03 0,08071706 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 7,971E-03 0,08027599 ! Schwann cell differentiation GO:0014037 5 5 0,000 7,971E-03 0,0798397 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 7,971E-03 0,07940814 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 7,971E-03 0,07898121 ! protein heterooligomerization GO:0051291 5 5 0,000 7,971E-03 0,07855885 ! regulation of gliogenesis GO:0014013 5 5 0,000 7,971E-03 0,07814099 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 7,971E-03 0,07772754 ! response to UV-B GO:0010224 5 5 0,000 7,971E-03 0,07731845 ! oligodendrocyte development GO:0014003 5 5 0,000 7,971E-03 0,07691364 ! hyaluronan metabolic process GO:0030212 5 5 0,000 7,971E-03 0,07651305 ! activated T cell proliferation GO:0050798 5 5 0,000 7,971E-03 0,07611661 ! interaction with symbiont GO:0051702 5 5 0,000 7,971E-03 0,07572425 ! cellular extravasation GO:0045123 5 5 0,000 7,971E-03 0,07533592 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 7,971E-03 0,07495156 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 7,971E-03 0,07457109 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 7,971E-03 0,07419447 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 7,971E-03 0,07382163 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 7,971E-03 0,07345253 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 7,971E-03 0,07308709 ! response to amine stimulus GO:0014075 5 5 0,000 7,971E-03 0,07272527 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 7,971E-03 0,07236702 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 7,971E-03 0,07201228 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 7,971E-03 0,071661 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 7,971E-03 0,07131313 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 7,971E-03 0,07096862 ! neuron recognition GO:0008038 5 5 0,000 7,971E-03 0,07062743 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 7,971E-03 0,0702895 ! decidualization GO:0046697 5 5 0,000 7,971E-03 0,06995479 ! hair follicle maturation GO:0048820 5 5 0,000 7,971E-03 0,06962325 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 7,971E-03 0,06929484 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 7,971E-03 0,06896951 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 7,971E-03 0,06864722 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 7,971E-03 0,06832793 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 7,971E-03 0,0680116 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 7,971E-03 0,06769818 ! postreplication repair GO:0006301 5 5 0,000 7,971E-03 0,06738764 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 7,971E-03 0,06707993 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 7,971E-03 0,06677502 ! histone methylation GO:0016571 5 5 0,000 7,971E-03 0,06647287 ! DNA methylation GO:0006306 5 5 0,000 7,971E-03 0,06617345 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 7,971E-03 0,06587671 ! T cell lineage commitment GO:0002360 5 5 0,000 7,971E-03 0,06558261 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 7,971E-03 0,06529113 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 7,971E-03 0,06500224 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 7,971E-03 0,06471588 ! intracellular cholesterol transport GO:0032367 5 5 0,000 7,971E-03 0,06443204 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 7,971E-03 0,06415068 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 7,971E-03 0,06387176 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 7,971E-03 0,06359526 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 7,971E-03 0,06332114 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 7,971E-03 0,06304938 ! sterol catabolic process GO:0016127 5 5 0,000 7,971E-03 0,06277994 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 7,971E-03 0,06251279 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 7,971E-03 0,0622479 ! detection of biotic stimulus GO:0009595 5 5 0,000 7,971E-03 0,06198525 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 7,971E-03 0,06172481 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 7,971E-03 0,06146655 ! zymogen activation GO:0031638 5 5 0,000 7,971E-03 0,06121044 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 7,971E-03 0,06095645 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 7,971E-03 0,06070457 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 7,971E-03 0,06045475 ! peptidyl-lysine modification GO:0018205 5 5 0,000 7,971E-03 0,06020699 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 7,971E-03 0,05996125 ! peptidyl-histidine modification GO:0018202 5 5 0,000 7,971E-03 0,0597175 ! nucleosome positioning GO:0016584 5 5 0,000 7,971E-03 0,05947573 ! regulation of isotype switching GO:0045191 5 5 0,000 7,971E-03 0,05923591 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 7,971E-03 0,05899801 ! negative regulation of neurological system process GO:0031645 5 5 0,000 7,971E-03 0,05876202 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 7,971E-03 0,05852791 ! glutathione biosynthetic process GO:0006750 5 5 0,000 7,971E-03 0,05829566 ! NADPH regeneration GO:0006740 5 5 0,000 7,971E-03 0,05806524 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 7,971E-03 0,05783664 ! positive regulation of epidermis development GO:0045684 5 5 0,000 7,971E-03 0,05760982 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 7,971E-03 0,05738479 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 7,971E-03 0,0571615 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 7,971E-03 0,05693994 ! sarcomere organization GO:0045214 5 5 0,000 7,971E-03 0,0567201 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 7,971E-03 0,05650194 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 7,971E-03 0,05628546 ! negative regulation of glucose transport GO:0010829 5 5 0,000 7,971E-03 0,05607063 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 7,971E-03 0,05585743 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 7,971E-03 0,05564585 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 7,971E-03 0,05543587 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 7,971E-03 0,05522746 ! spleen development GO:0048536 5 5 0,000 7,971E-03 0,05502062 ! male genitalia development GO:0030539 5 5 0,000 7,971E-03 0,05481532 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 7,971E-03 0,05461154 ! quaternary ammonium group transport GO:0015697 5 5 0,000 7,971E-03 0,05440928 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 7,971E-03 0,05420851 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 7,971E-03 0,05400921 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 7,971E-03 0,05381137 ! removal of superoxide radicals GO:0019430 6 5 0,000 7,971E-03 0,05361498 ! myeloid cell homeostasis GO:0002262 5 5 0,000 7,971E-03 0,05342002 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 7,971E-03 0,05322647 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 7,971E-03 0,05303432 ! ATP catabolic process GO:0006200 5 5 0,000 7,971E-03 0,05284354 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 7,971E-03 0,05265414 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 7,971E-03 0,05246609 ! blastocyst formation GO:0001825 5 5 0,000 7,971E-03 0,05227938 ! regulation of fibrinolysis GO:0051917 5 5 0,000 7,971E-03 0,05209399 ! embryonic gut development GO:0048566 5 5 0,000 7,971E-03 0,05190991 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 7,971E-03 0,05172713 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 7,971E-03 0,05154563 ! activation of innate immune response GO:0002218 5 5 0,000 7,971E-03 0,0513654 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 7,971E-03 0,05118643 ! catecholamine transport GO:0051937 5 5 0,000 7,971E-03 0,0510087 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 7,971E-03 0,0508322 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 7,971E-03 0,05065692 ! muscle adaptation GO:0043500 5 5 0,000 7,971E-03 0,05048284 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 7,971E-03 0,05030995 ! embryonic heart tube development GO:0035050 5 5 0,000 7,971E-03 0,05013824 ! cardiac cell differentiation GO:0035051 6 5 0,000 7,971E-03 0,04996771 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 7,971E-03 0,04979832 ! defense response to fungus GO:0050832 5 5 0,000 7,971E-03 0,04963009 ! lysogeny GO:0030069 5 5 0,000 7,971E-03 0,04946298 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 7,971E-03 0,049297 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 7,971E-03 0,04913212 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 7,971E-03 0,04896835 ! response to nicotine GO:0035094 5 5 0,000 7,971E-03 0,04880567 ! establishment of cell polarity GO:0030010 5 5 0,000 7,971E-03 0,04864406 ! mitochondrion localization GO:0051646 5 5 0,000 7,971E-03 0,04848352 ! nucleus localization GO:0051647 5 5 0,000 7,971E-03 0,04832403 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 7,971E-03 0,04816559 ! male gamete generation GO:0048232 90 88 1,000 8,254E-03 0,04971199 GO:0007283|spermatogenesis, ! brain development GO:0007420 91 90 1,000 8,62E-03 0,05175078 ! DNA replication GO:0006260 91 91 1,000 8,806E-03 0,05269592 ! positive regulation of immune system process GO:0002684 92 92 1,000 8,994E-03 0,05364579 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 9,558E-03 0,05682516 ! axon extension GO:0048675 7 6 0,000 9,558E-03 0,05664245 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 9,558E-03 0,0564609 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 9,558E-03 0,05628051 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 9,558E-03 0,05610128 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 9,558E-03 0,05592318 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 9,558E-03 0,0557462 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 9,558E-03 0,05557035 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 9,558E-03 0,0553956 ! virus-host interaction GO:0019048 6 6 0,000 9,558E-03 0,05522195 ! regulation of S phase GO:0033261 6 6 0,000 9,558E-03 0,05504938 ! myotube differentiation GO:0014902 6 6 0,000 9,558E-03 0,05487788 ! regulation of B cell proliferation GO:0030888 6 6 0,000 9,558E-03 0,05470746 ! bone remodeling GO:0046849 6 6 0,000 9,558E-03 0,05453808 ! N-glycan processing GO:0006491 6 6 0,000 9,558E-03 0,05436975 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 9,558E-03 0,05420246 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 9,558E-03 0,0540362 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 9,558E-03 0,05387095 ! retina development in camera-type eye GO:0060041 6 6 0,000 9,558E-03 0,05370671 ! RNA methylation GO:0001510 6 6 0,000 9,558E-03 0,05354347 ! cartilage condensation GO:0001502 7 6 0,000 9,558E-03 0,05338121 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 9,558E-03 0,05321994 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 9,558E-03 0,05305964 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 9,558E-03 0,0529003 ! artery development GO:0060840 6 6 0,000 9,558E-03 0,05274192 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 9,558E-03 0,05258448 ! bile acid metabolic process GO:0008206 6 6 0,000 9,558E-03 0,05242798 ! androgen metabolic process GO:0008209 6 6 0,000 9,558E-03 0,05227241 ! estrogen metabolic process GO:0008210 6 6 0,000 9,558E-03 0,05211775 ! limbic system development GO:0021761 7 6 0,000 9,558E-03 0,05196401 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 9,558E-03 0,05181118 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 9,558E-03 0,05165924 ! positive regulation of heart contraction GO:0045823 6 6 0,000 9,558E-03 0,05150819 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 9,558E-03 0,05135802 ! pathogenesis GO:0009405 6 6 0,000 9,558E-03 0,05120872 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 9,558E-03 0,05106029 ! positive regulation of cell growth GO:0030307 6 6 0,000 9,558E-03 0,05091272 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 9,558E-03 0,050766 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 9,558E-03 0,05062012 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 9,558E-03 0,05047507 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 9,558E-03 0,05033086 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 9,558E-03 0,05018747 ! arginine metabolic process GO:0006525 6 6 0,000 9,558E-03 0,05004489 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 9,558E-03 0,04990312 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 9,558E-03 0,04976215 ! glutamate catabolic process GO:0006538 7 6 0,000 9,558E-03 0,04962197 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 9,558E-03 0,04948259 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 9,558E-03 0,04934398 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 9,558E-03 0,04920615 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 9,558E-03 0,04906908 ! ER overload response GO:0006983 6 6 0,000 9,558E-03 0,04893278 ! V(D)J recombination GO:0033151 6 6 0,000 9,558E-03 0,04879723 ! focal adhesion formation GO:0048041 7 6 0,000 9,558E-03 0,04866243 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 9,558E-03 0,04852838 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 9,558E-03 0,04839506 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 9,558E-03 0,04826247 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 9,558E-03 0,0481306 ! regulation of heart rate GO:0002027 6 6 0,000 9,558E-03 0,04799946 ! lipid digestion GO:0044241 6 6 0,000 9,558E-03 0,04786902 ! asymmetric protein localization GO:0008105 6 6 0,000 9,558E-03 0,0477393 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 9,558E-03 0,04761027 ! phagocytosis, engulfment GO:0006911 6 6 0,000 9,558E-03 0,04748194 ! Rac protein signal transduction GO:0016601 6 6 0,000 9,558E-03 0,0473543 ! regulation of vascular permeability GO:0043114 6 6 0,000 9,558E-03 0,04722735 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 9,558E-03 0,04710107 ! ruffle organization GO:0031529 6 6 0,000 9,558E-03 0,04697547 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 9,558E-03 0,04685053 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 9,558E-03 0,04672626 ! retinoic acid metabolic process GO:0042573 6 6 0,000 9,558E-03 0,04660265 ! neutral amino acid transport GO:0015804 6 6 0,000 9,558E-03 0,04647968 ! L-amino acid transport GO:0015807 6 6 0,000 9,558E-03 0,04635737 ! bone mineralization GO:0030282 6 6 0,000 9,558E-03 0,0462357 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 9,558E-03 0,04611466 ! negative regulation of ossification GO:0030279 6 6 0,000 9,558E-03 0,04599426 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 9,558E-03 0,04587448 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 9,558E-03 0,04575533 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 9,558E-03 0,04563679 ! purine base biosynthetic process GO:0009113 6 6 0,000 9,558E-03 0,04551886 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 9,558E-03 0,04540155 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 9,558E-03 0,04528483 ! regulation of phagocytosis GO:0050764 6 6 0,000 9,558E-03 0,04516872 ! regulation of organ growth GO:0046620 6 6 0,000 9,558E-03 0,0450532 ! regulation of circadian rhythm GO:0042752 6 6 0,000 9,558E-03 0,04493827 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 9,558E-03 0,04482392 ! response to dsRNA GO:0043331 6 6 0,000 9,558E-03 0,04471015 ! DNA unwinding during replication GO:0006268 6 6 0,000 9,558E-03 0,04459696 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 9,558E-03 0,04448434 ! genitalia development GO:0048806 6 6 0,000 9,558E-03 0,04437229 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 9,558E-03 0,04426081 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 9,558E-03 0,04414988 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 9,558E-03 0,0440395 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 9,558E-03 0,04392968 ! multicellular organismal aging GO:0010259 6 6 0,000 9,558E-03 0,0438204 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 9,558E-03 0,04371166 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 9,558E-03 0,04360347 ! erythrocyte development GO:0048821 6 6 0,000 9,558E-03 0,0434958 ! renal water homeostasis GO:0003091 6 6 0,000 9,558E-03 0,04338867 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 9,558E-03 0,04328207 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 9,558E-03 0,04317598 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 9,558E-03 0,04307042 ! ribosome assembly GO:0042255 6 6 0,000 9,558E-03 0,04296537 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 9,558E-03 0,04286083 ! diencephalon development GO:0021536 6 6 0,000 9,558E-03 0,0427568 ! fucose catabolic process GO:0019317 6 6 0,000 9,558E-03 0,04265327 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 9,558E-03 0,04255024 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 9,558E-03 0,04244771 ! regulation of lipid transport GO:0032368 6 6 0,000 9,558E-03 0,04234567 ! regulation of cell division GO:0051302 6 6 0,000 9,558E-03 0,04224413 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 9,558E-03 0,04214306 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 9,558E-03 0,04204248 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 9,558E-03 0,04194238 ! salivary gland morphogenesis GO:0007435 6 6 0,000 9,558E-03 0,04184276 ! neuroblast proliferation GO:0007405 6 6 0,000 9,558E-03 0,0417436 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 9,558E-03 0,04164492 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 9,558E-03 0,0415467 ! regulation of glucose transport GO:0010827 6 6 0,000 9,558E-03 0,04144894 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 9,558E-03 0,04135164 ! methionine biosynthetic process GO:0009086 6 6 0,000 9,558E-03 0,0412548 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 9,558E-03 0,04115841 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 9,558E-03 0,04106247 ! thymus development GO:0048538 6 6 0,000 9,558E-03 0,04096698 ! lymph node development GO:0048535 6 6 0,000 9,558E-03 0,04087193 ! organic cation transport GO:0015695 6 6 0,000 9,558E-03 0,04077732 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 9,558E-03 0,04068314 ! regulation of RNA splicing GO:0043484 6 6 0,000 9,558E-03 0,0405894 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 9,558E-03 0,04049609 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 9,558E-03 0,04040321 ! sperm-egg recognition GO:0035036 7 6 0,000 9,558E-03 0,04031076 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 9,558E-03 0,04021872 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 9,558E-03 0,04012711 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 9,558E-03 0,04003591 ! alditol metabolic process GO:0019400 6 6 0,000 9,558E-03 0,03994513 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 9,558E-03 0,03985475 ! regulation of amino acid transport GO:0051955 6 6 0,000 9,558E-03 0,03976479 ! maternal placenta development GO:0001893 6 6 0,000 9,558E-03 0,03967523 ! regulation of embryonic development GO:0045995 6 6 0,000 9,558E-03 0,03958607 ! negative regulation of immune effector process GO:0002698 6 6 0,000 9,558E-03 0,03949731 ! localization within membrane GO:0051668 6 6 0,000 9,558E-03 0,03940895 ! regulation of cell growth GO:0001558 97 96 1,000 9,764E-03 0,04016668 ! endocytosis GO:0006897 99 98 1,000 0,0101593 0,04170065 GO:0010324|membrane invagination, ! anti-apoptosis GO:0006916 100 99 1,000 0,01035973 0,04242884 ! respiratory burst GO:0045730 7 7 0,000 0,01114316 0,04553623 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,01114316 0,04543549 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,01114316 0,04533519 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,01114316 0,04523533 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,01114316 0,04513591 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,01114316 0,04503693 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,01114316 0,04493838 ! regulation of chemokine production GO:0032642 7 7 0,000 0,01114316 0,04484026 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,01114316 0,04474257 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,01114316 0,0446453 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,01114316 0,04454846 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,01114316 0,04445203 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,01114316 0,04435603 ! gene silencing by RNA GO:0031047 7 7 0,000 0,01114316 0,04426043 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,01114316 0,04416525 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,01114316 0,04407047 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,01114316 0,0439761 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,01114316 0,04388214 ! axis specification GO:0009798 7 7 0,000 0,01114316 0,04378857 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,01114316 0,0436954 ! visual behavior GO:0007632 7 7 0,000 0,01114316 0,04360263 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,01114316 0,04351025 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,01114316 0,04341827 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,01114316 0,04332667 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,01114316 0,04323545 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,01114316 0,04314462 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,01114316 0,04305417 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,01114316 0,0429641 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,01114316 0,04287441 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,01114316 0,04278508 ! digestive system development GO:0055123 7 7 0,000 0,01114316 0,04269613 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,01114316 0,04260755 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,01114316 0,04251934 ! protein targeting to ER GO:0045047 8 7 0,000 0,01114316 0,04243149 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,01114316 0,042344 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,01114316 0,04225687 ! endoderm development GO:0007492 7 7 0,000 0,01114316 0,0421701 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,01114316 0,04208369 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,01114316 0,04199763 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,01114316 0,04191192 ! response to hexose stimulus GO:0009746 7 7 0,000 0,01114316 0,04182656 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,01114316 0,04174155 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,01114316 0,04165688 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,01114316 0,04157255 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,01114316 0,04148857 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,01114316 0,04140492 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,01114316 0,04132161 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,01114316 0,04123863 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,01114316 0,04115599 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,01114316 0,04107368 ! response to X-ray GO:0010165 7 7 0,000 0,01114316 0,0409917 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,01114316 0,04091004 ! UV protection GO:0009650 7 7 0,000 0,01114316 0,04082871 ! DNA integration GO:0015074 7 7 0,000 0,01114316 0,0407477 ! myofibril assembly GO:0030239 7 7 0,000 0,01114316 0,04066701 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,01114316 0,04058664 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,01114316 0,04050659 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,01114316 0,04042685 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,01114316 0,04034743 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,01114316 0,04026831 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,01114316 0,04018951 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,01114316 0,04011102 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,01114316 0,04003283 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,01114316 0,03995494 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,01114316 0,03987736 ! axon cargo transport GO:0008088 7 7 0,000 0,01114316 0,03980008 ! eating behavior GO:0042755 7 7 0,000 0,01114316 0,0397231 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,01114316 0,03964641 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,01114316 0,03957002 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,01114316 0,03949392 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,01114316 0,03941812 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,01114316 0,03934261 ! cranial nerve development GO:0021545 7 7 0,000 0,01114316 0,03926738 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,01114316 0,03919244 ! induction of an organ GO:0001759 7 7 0,000 0,01114316 0,03911779 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,01114316 0,03904342 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,01114316 0,03896934 ! autonomic nervous system development GO:0048483 7 7 0,000 0,01114316 0,03889553 ! intracellular lipid transport GO:0032365 7 7 0,000 0,01114316 0,038822 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,01114316 0,03874875 ! platelet activation GO:0030168 8 7 0,000 0,01114316 0,03867578 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,01114316 0,03860308 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,01114316 0,03853066 ! natural killer cell activation GO:0030101 7 7 0,000 0,01114316 0,0384585 ! response to gamma radiation GO:0010332 8 7 0,000 0,01114316 0,03838662 ! NADP metabolic process GO:0006739 7 7 0,000 0,01114316 0,038315 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,01114316 0,03824365 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,01114316 0,03817257 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,01114316 0,03810174 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,01114316 0,03803119 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,01114316 0,03796089 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,01114316 0,03789085 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,01114316 0,03782107 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,01114316 0,03775154 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,01114316 0,03768228 ! cell-cell recognition GO:0009988 8 7 0,000 0,01114316 0,03761326 ! hormone catabolic process GO:0042447 7 7 0,000 0,01114316 0,0375445 ! dopamine metabolic process GO:0042417 7 7 0,000 0,01114316 0,03747599 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,01114316 0,03740772 ! oxygen transport GO:0015671 7 7 0,000 0,01114316 0,03733971 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,01114316 0,03727194 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,01114316 0,03720442 ! regulation of axon extension GO:0030516 7 7 0,000 0,01114316 0,03713714 ! cell killing GO:0001906 7 7 0,000 0,01114316 0,03707011 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,01114316 0,03700332 ! adult feeding behavior GO:0008343 7 7 0,000 0,01114316 0,03693676 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,01114316 0,03687045 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,01114316 0,03680437 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,01114316 0,03673853 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,01114316 0,03667293 ! response to cold GO:0009409 7 7 0,000 0,01114316 0,03660756 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,01272579 0,04173244 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,01272579 0,04165831 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,01272579 0,04158445 ! positive regulation of translation GO:0045727 8 8 0,000 0,01272579 0,04151085 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,01272579 0,04143751 ! superoxide anion generation GO:0042554 8 8 0,000 0,01272579 0,04136443 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,01272579 0,0412916 ! cGMP metabolic process GO:0046068 8 8 0,000 0,01272579 0,04121903 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,01272579 0,04114672 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,01272579 0,04107466 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,01272579 0,04100285 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,01272579 0,04093129 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,01272579 0,04085998 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,01272579 0,04078892 ! zinc ion transport GO:0006829 8 8 0,000 0,01272579 0,04071811 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,01272579 0,04064754 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,01272579 0,04057721 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,01272579 0,04050713 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,01272579 0,04043729 ! lipid localization GO:0010876 8 8 0,000 0,01272579 0,04036769 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,01272579 0,04029833 ! response to cAMP GO:0051591 8 8 0,000 0,01272579 0,04022921 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,01272579 0,04016032 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,01272579 0,04009167 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,01272579 0,04002326 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,01272579 0,03995508 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,01272579 0,03988713 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,01272579 0,03981941 ! sensory perception of taste GO:0050909 8 8 0,000 0,01272579 0,03975191 ! organelle fusion GO:0048284 8 8 0,000 0,01272579 0,03968465 ! pancreas development GO:0031016 8 8 0,000 0,01272579 0,03961762 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,01272579 0,03955081 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,01272579 0,03948423 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,01272579 0,03941787 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,01272579 0,03935173 ! sperm motility GO:0030317 8 8 0,000 0,01272579 0,03928581 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,01272579 0,03922012 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,01272579 0,03915464 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,01272579 0,03908938 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,01272579 0,03902434 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,01272579 0,03895952 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01272579 0,03889491 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,01272579 0,03883051 ! Golgi organization GO:0007030 8 8 0,000 0,01272579 0,03876633 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,01272579 0,03870236 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,01272579 0,0386386 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,01272579 0,03857505 ! fructose metabolic process GO:0006000 8 8 0,000 0,01272579 0,03851171 ! mannose metabolic process GO:0006013 9 8 0,000 0,01272579 0,03844857 ! NAD metabolic process GO:0019674 8 8 0,000 0,01272579 0,03838565 ! sex determination GO:0007530 8 8 0,000 0,01272579 0,03832292 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,01272579 0,03826041 ! plasma membrane fusion GO:0045026 8 8 0,000 0,01272579 0,03819809 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,01272579 0,03813598 ! response to fungus GO:0009620 8 8 0,000 0,01272579 0,03807407 ! stem cell differentiation GO:0048863 8 8 0,000 0,01272579 0,03801237 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,01272579 0,03795086 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,01272579 0,03788955 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,01272579 0,03782844 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,01272579 0,03776752 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01272579 0,0377068 ! regulation of vasodilation GO:0042312 8 8 0,000 0,01272579 0,03764628 ! vasoconstriction GO:0042310 8 8 0,000 0,01272579 0,03758595 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,01272579 0,03752581 ! muscle cell development GO:0055001 8 8 0,000 0,01272579 0,03746586 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,01272579 0,03740611 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,01272579 0,03734654 ! sensory perception of pain GO:0019233 8 8 0,000 0,01272579 0,03728717 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,01272579 0,03722798 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,01272579 0,03716899 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,01272579 0,03711017 ! chromatin silencing GO:0006342 8 8 0,000 0,01272579 0,03705155 ! tissue regeneration GO:0042246 8 8 0,000 0,01272579 0,03699311 ! salivary gland development GO:0007431 8 8 0,000 0,01272579 0,03693485 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,01272579 0,03687678 ! T cell homeostasis GO:0043029 8 8 0,000 0,01272579 0,03681888 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,01272579 0,03676118 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,01272579 0,03670365 ! water homeostasis GO:0030104 8 8 0,000 0,01272579 0,0366463 ! cofactor transport GO:0051181 8 8 0,000 0,01272579 0,03658913 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,01272579 0,03653213 ! acid secretion GO:0046717 8 8 0,000 0,01272579 0,03647532 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,01272579 0,03641868 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,01272579 0,03636222 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,01272579 0,03630593 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,01272579 0,03624981 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,01272579 0,03619387 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,01272579 0,0361381 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,01272579 0,03608251 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,01272579 0,03602708 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,01272579 0,03597182 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,01272579 0,03591674 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,01272579 0,03586182 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,01272579 0,03580707 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,01272579 0,03575248 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,01272579 0,03569807 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,01272579 0,03564381 ! developmental induction GO:0031128 8 8 0,000 0,01272579 0,03558973 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,01272579 0,0355358 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,01272579 0,03548204 ! actin filament polymerization GO:0030041 9 8 0,000 0,01272579 0,03542844 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,01272579 0,03537501 ! peptide hormone processing GO:0016486 8 8 0,000 0,01272579 0,03532173 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,01272579 0,03526862 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,01272579 0,03521566 ! lactation GO:0007595 10 9 0,000 0,01430612 0,0395295 ! embryonic pattern specification GO:0009880 10 9 0,000 0,01430612 0,03947032 ! positive regulation of cell size GO:0045793 9 9 0,000 0,01430612 0,03941132 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,01430612 0,0393525 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,01430612 0,03929385 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,01430612 0,03923538 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,01430612 0,03917708 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,01430612 0,03911895 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,01430612 0,039061 ! viral genome replication GO:0019079 9 9 0,000 0,01430612 0,03900322 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,01430612 0,03894561 ! copper ion transport GO:0006825 9 9 0,000 0,01430612 0,03888816 ! lipid phosphorylation GO:0046834 9 9 0,000 0,01430612 0,03883089 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,01430612 0,03877379 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,01430612 0,03871685 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,01430612 0,03866008 ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,01430612 0,03860348 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,01430612 0,03854704 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,01430612 0,03849077 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,01430612 0,03843466 ! phospholipid efflux GO:0033700 9 9 0,000 0,01430612 0,03837871 ! response to alkaloid GO:0043279 10 9 0,000 0,01430612 0,03832293 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,01430612 0,03826731 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,01430612 0,03821185 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,01430612 0,03815655 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,01430612 0,03810141 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,01430612 0,03804643 ! response to ethanol GO:0045471 9 9 0,000 0,01430612 0,03799161 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,01430612 0,03793694 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,01430612 0,03788244 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,01430612 0,03782808 ! methionine metabolic process GO:0006555 9 9 0,000 0,01430612 0,03777389 ! glutamine metabolic process GO:0006541 9 9 0,000 0,01430612 0,03771985 ! cerebral cortex development GO:0021987 9 9 0,000 0,01430612 0,03766596 ! response to osmotic stress GO:0006970 9 9 0,000 0,01430612 0,03761223 ! pigmentation during development GO:0048066 9 9 0,000 0,01430612 0,03755865 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,01430612 0,03750523 ! central nervous system neuron development GO:0021954 10 9 0,000 0,01430612 0,03745195 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,01430612 0,03739883 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,01430612 0,03734586 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,01430612 0,03729303 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,01430612 0,03724036 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,01430612 0,03718783 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,01430612 0,03713546 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,01430612 0,03708323 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,01430612 0,03703114 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,01430612 0,03697921 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,01430612 0,03692742 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,01430612 0,03687577 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,01430612 0,03682427 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,01430612 0,03677291 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,01430612 0,03672169 ! DNA replication initiation GO:0006270 9 9 0,000 0,01430612 0,03667062 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,01430612 0,03661969 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,01430612 0,0365689 ! regulation of cellular pH GO:0030641 9 9 0,000 0,01430612 0,03651825 ! histone acetylation GO:0016573 9 9 0,000 0,01430612 0,03646774 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,01430612 0,03641737 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,01430612 0,03636714 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,01430612 0,03631705 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,01430612 0,03626709 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,01430612 0,03621727 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,01430612 0,03616759 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,01430612 0,03611805 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,01430612 0,03606864 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,01430612 0,03601936 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,01430612 0,03597022 ! collagen catabolic process GO:0030574 9 9 0,000 0,01430612 0,03592122 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,01430612 0,03587235 ! purine base metabolic process GO:0006144 9 9 0,000 0,01430612 0,03582361 ! gas transport GO:0015669 9 9 0,000 0,01430612 0,035775 ! cholesterol efflux GO:0033344 9 9 0,000 0,01430612 0,03572652 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,01430612 0,03567818 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,01430612 0,03562997 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,01430612 0,03558188 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,01430612 0,03553393 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,01430612 0,0354861 ! defense response to virus GO:0051607 9 9 0,000 0,01430612 0,03543841 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,01430612 0,03539084 ! actin filament-based movement GO:0030048 9 9 0,000 0,01430612 0,0353434 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,01430612 0,03529608 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01588415 0,03913701 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,01588415 0,03908475 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01588415 0,03903264 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01588415 0,03898067 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,01588415 0,03892883 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01588415 0,03887713 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01588415 0,03882557 ! neuron maturation GO:0042551 10 10 0,000 0,01588415 0,03877415 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01588415 0,03872286 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01588415 0,03867171 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01588415 0,03862069 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01588415 0,0385698 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01588415 0,03851905 ! hormone secretion GO:0046879 10 10 0,000 0,01588415 0,03846844 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01588415 0,03841795 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01588415 0,0383676 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,01588415 0,03831738 ! inositol metabolic process GO:0006020 10 10 0,000 0,01588415 0,0382673 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01588415 0,03821734 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01588415 0,03816751 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01588415 0,03811781 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01588415 0,03806825 ! glial cell development GO:0021782 10 10 0,000 0,01588415 0,03801881 ! phototransduction GO:0007602 11 10 0,000 0,01588415 0,0379695 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01588415 0,03792031 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01588415 0,03787126 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,01588415 0,03782233 ! fat cell differentiation GO:0045444 10 10 0,000 0,01588415 0,03777352 ! myoblast differentiation GO:0045445 10 10 0,000 0,01588415 0,03772485 ! centrosome cycle GO:0007098 10 10 0,000 0,01588415 0,03767629 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01588415 0,03762787 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01588415 0,03757956 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01588415 0,03753139 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01588415 0,03748333 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01588415 0,0374354 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,01588415 0,03738759 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01588415 0,0373399 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01588415 0,03729233 ! plasma membrane organization GO:0007009 10 10 0,000 0,01588415 0,03724489 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01588415 0,03719756 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01588415 0,03715036 ! lysosomal transport GO:0007041 10 10 0,000 0,01588415 0,03710327 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01588415 0,03705631 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01588415 0,03700946 ! vesicle coating GO:0006901 10 10 0,000 0,01588415 0,03696273 ! exocrine system development GO:0035272 10 10 0,000 0,01588415 0,03691612 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01588415 0,03686962 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01588415 0,03682325 ! embryo implantation GO:0007566 11 10 0,000 0,01588415 0,03677699 ! regulation of protein binding GO:0043393 11 10 0,000 0,01588415 0,03673084 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01588415 0,03668481 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01588415 0,0366389 GO:0070585|protein localization in mitochondrion, ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01588415 0,0365931 ! protein export from nucleus GO:0006611 10 10 0,000 0,01588415 0,03654742 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01588415 0,03650185 ! cytolysis GO:0019835 10 10 0,000 0,01588415 0,03645639 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01588415 0,03641105 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01588415 0,03636581 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01588415 0,0363207 ! histone deacetylation GO:0016575 10 10 0,000 0,01588415 0,03627569 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01588415 0,03623079 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01588415 0,03618601 ! gland morphogenesis GO:0022612 10 10 0,000 0,01588415 0,03614133 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01588415 0,03609677 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01588415 0,03605232 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01588415 0,03600797 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01588415 0,03596374 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,01588415 0,03591961 ! regulation of epidermis development GO:0045682 10 10 0,000 0,01588415 0,03587559 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01588415 0,03583168 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,01588415 0,03578787 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01588415 0,03574418 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01588415 0,03570059 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01588415 0,0356571 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01588415 0,03561372 ! nerve development GO:0021675 10 10 0,000 0,01588415 0,03557045 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,01588415 0,03552728 ! gut development GO:0048565 10 10 0,000 0,01588415 0,03548422 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01588415 0,03544126 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,01588415 0,03539841 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01588415 0,03535565 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01588415 0,035313 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01588415 0,03527046 ! protein stabilization GO:0050821 10 10 0,000 0,01588415 0,03522802 ! protein secretion GO:0009306 11 11 0,000 0,01745988 0,03867615 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01745988 0,03862972 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01745988 0,0385834 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01745988 0,03853719 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01745988 0,03849109 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01745988 0,03844511 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,01745988 0,03839923 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01745988 0,03835346 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01745988 0,0383078 ! skin development GO:0043588 11 11 0,000 0,01745988 0,03826225 ! signal complex assembly GO:0007172 11 11 0,000 0,01745988 0,03821681 ! microtubule-based transport GO:0010970 11 11 0,000 0,01745988 0,03817148 ! endothelial cell migration GO:0043542 11 11 0,000 0,01745988 0,03812625 ! peroxisomal transport GO:0043574 11 11 0,000 0,01745988 0,03808113 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01745988 0,03803612 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,01745988 0,03799121 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01745988 0,03794641 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01745988 0,03790171 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01745988 0,03785712 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01745988 0,03781264 ! T cell proliferation GO:0042098 11 11 0,000 0,01745988 0,03776826 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01745988 0,03772398 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01745988 0,03767981 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,01745988 0,03763574 ! spinal cord development GO:0021510 11 11 0,000 0,01745988 0,03759177 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01745988 0,0375479 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01745988 0,03750414 ! cellular response to starvation GO:0009267 11 11 0,000 0,01745988 0,03746048 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01745988 0,03741692 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,01745988 0,03737347 ! digestive system process GO:0022600 11 11 0,000 0,01745988 0,03733011 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01745988 0,03728685 ! fucose metabolic process GO:0006004 11 11 0,000 0,01745988 0,0372437 ! membrane budding GO:0006900 11 11 0,000 0,01745988 0,03720064 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,01745988 0,03715768 ! monoamine transport GO:0015844 11 11 0,000 0,01745988 0,03711483 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01745988 0,03707207 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01745988 0,03702941 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01745988 0,03698684 ! body fluid secretion GO:0007589 11 11 0,000 0,01745988 0,03694438 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01745988 0,03690201 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01745988 0,03685974 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01745988 0,03681757 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01745988 0,03677549 ! membrane depolarization GO:0051899 11 11 0,000 0,01745988 0,03673351 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01745988 0,03669162 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01745988 0,03664983 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,01745988 0,03660814 ! oogenesis GO:0048477 11 11 0,000 0,01745988 0,03656654 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01745988 0,03652503 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01745988 0,03648362 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,01745988 0,0364423 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,01745988 0,03640108 ! muscle maintenance GO:0046716 12 11 0,000 0,01745988 0,03635995 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01745988 0,03631891 ! hindbrain development GO:0030902 11 11 0,000 0,01745988 0,03627796 ! steroid catabolic process GO:0006706 11 11 0,000 0,01745988 0,03623711 ! endocrine process GO:0050886 11 11 0,000 0,01745988 0,03619635 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01745988 0,03615568 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01745988 0,0361151 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01745988 0,03607461 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01745988 0,03603421 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,01903331 0,03923758 ! translational initiation GO:0006413 12 12 0,000 0,01903331 0,03919374 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,01903331 0,03915 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,01903331 0,03910635 ! initiation of viral infection GO:0019059 12 12 0,000 0,01903331 0,03906281 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,01903331 0,03901935 ! iron ion transport GO:0006826 13 12 0,000 0,01903331 0,038976 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,01903331 0,03893274 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,01903331 0,03888958 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,01903331 0,03884651 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,01903331 0,03880354 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,01903331 0,03876066 ! collagen metabolic process GO:0032963 12 12 0,000 0,01903331 0,03871788 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,01903331 0,03867519 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,01903331 0,0386326 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,01903331 0,0385901 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,01903331 0,03854769 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,01903331 0,03850538 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,01903331 0,03846316 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,01903331 0,03842103 ! actomyosin structure organization GO:0031032 12 12 0,000 0,01903331 0,03837899 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,01903331 0,03833705 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,01903331 0,0382952 ! retinoid metabolic process GO:0001523 12 12 0,000 0,01903331 0,03825343 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,01903331 0,03821176 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,01903331 0,03817018 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,01903331 0,03812869 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,01903331 0,0380873 ! acute-phase response GO:0006953 12 12 0,000 0,01903331 0,03804599 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01903331 0,03800477 ! vacuolar transport GO:0007034 12 12 0,000 0,01903331 0,03796364 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,01903331 0,03792259 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,01903331 0,03788164 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,01903331 0,03784078 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,01903331 0,0378 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,01903331 0,03775931 ! male gonad development GO:0008584 12 12 0,000 0,01903331 0,03771871 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,01903331 0,03767819 ! renal system process GO:0003014 12 12 0,000 0,01903331 0,03763777 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,01903331 0,03759743 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,01903331 0,03755717 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,01903331 0,037517 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,01903331 0,03747692 ! pallium development GO:0021543 13 12 0,000 0,01903331 0,03743693 ! cell fate determination GO:0001709 12 12 0,000 0,01903331 0,03739701 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,01903331 0,03735719 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,01903331 0,03731745 ! somitogenesis GO:0001756 13 12 0,000 0,01903331 0,03727779 ! G1 phase GO:0051318 13 12 0,000 0,01903331 0,03723822 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,01903331 0,03719873 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,01903331 0,03715932 ! detection of light stimulus GO:0009583 13 12 0,000 0,01903331 0,03712 ! synaptogenesis GO:0007416 12 12 0,000 0,01903331 0,03708076 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,01903331 0,0370416 ! hormone transport GO:0009914 12 12 0,000 0,01903331 0,03700253 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,01903331 0,03696354 ! heme biosynthetic process GO:0006783 12 12 0,000 0,01903331 0,03692463 ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,01903331 0,0368858 ! neural tube closure GO:0001843 13 12 0,000 0,01903331 0,03684706 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,01903331 0,03680839 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,01903331 0,03676981 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,01903331 0,03673131 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,02060446 0,03972178 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,02060446 0,03968027 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,02060446 0,03963885 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,02060446 0,03959752 ! phenol metabolic process GO:0018958 13 13 0,000 0,02060446 0,03955627 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,02060446 0,03951511 ! gluconeogenesis GO:0006094 13 13 0,000 0,02060446 0,03947404 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,02060446 0,03943304 ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,02060446 0,03939214 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,02060446 0,03935132 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,02060446 0,03931058 ! regeneration GO:0031099 13 13 0,000 0,02060446 0,03926993 ! keratinization GO:0031424 13 13 0,000 0,02060446 0,03922936 ! post-embryonic development GO:0009791 14 13 0,000 0,02060446 0,03918888 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,02060446 0,03914848 ! patterning of blood vessels GO:0001569 13 13 0,000 0,02060446 0,03910816 ! vasculogenesis GO:0001570 13 13 0,000 0,02060446 0,03906792 ! regulation of innate immune response GO:0045088 13 13 0,000 0,02060446 0,03902777 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,02060446 0,0389877 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,02060446 0,03894771 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,02060446 0,03890781 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,02060446 0,03886799 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,02060446 0,03882824 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,02060446 0,03878858 ! autophagy GO:0006914 13 13 0,000 0,02060446 0,038749 ! receptor metabolic process GO:0043112 14 13 0,000 0,02060446 0,0387095 ! actin filament bundle formation GO:0051017 13 13 0,000 0,02060446 0,03867008 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,02060446 0,03863074 ! ureteric bud development GO:0001657 13 13 0,000 0,02060446 0,03859149 ! cell aging GO:0007569 13 13 0,000 0,02060446 0,03855231 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,02060446 0,03851321 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,02060446 0,03847419 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,02060446 0,03843524 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,02060446 0,03839638 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,02060446 0,0383576 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,02060446 0,03831889 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,02060446 0,03828026 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,02060446 0,03824171 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,02060446 0,03820324 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,02060446 0,03816485 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,02060446 0,03812653 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,02060446 0,03808829 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,02060446 0,03805012 ! vasodilation GO:0042311 14 13 0,000 0,02060446 0,03801203 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,02060446 0,03797402 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,02060446 0,03793609 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,02060446 0,03789823 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,02060446 0,03786044 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,02060446 0,03782273 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,02060446 0,0377851 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,02060446 0,03774754 ! immunoglobulin production GO:0002377 13 13 0,000 0,02060446 0,03771005 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,02060446 0,03767264 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,02060446 0,0376353 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,02060446 0,03759804 ! cell-cell junction organization GO:0045216 13 13 0,000 0,02060446 0,03756085 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,02060446 0,03752374 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,02060446 0,03748669 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,02060446 0,03744973 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,02060446 0,03741283 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,02060446 0,03737601 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,02060446 0,03733925 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,02060446 0,03730258 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,02060446 0,03726597 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,02060446 0,03722943 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,02060446 0,03719297 ! blastocyst development GO:0001824 13 13 0,000 0,02060446 0,03715658 ! telomere organization GO:0032200 13 13 0,000 0,02060446 0,03712026 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,02060446 0,03708401 ! regulation of amine transport GO:0051952 13 13 0,000 0,02060446 0,03704783 ! tissue homeostasis GO:0001894 13 13 0,000 0,02060446 0,03701172 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,02060446 0,03697568 ! protein tetramerization GO:0051262 13 13 0,000 0,02060446 0,03693971 ! neuron fate commitment GO:0048663 14 14 0,000 0,02217332 0,03971373 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,02217332 0,03967517 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,02217332 0,03963669 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,02217332 0,03959828 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,02217332 0,03955995 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,02217332 0,03952169 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,02217332 0,03948351 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,02217332 0,03944539 ! protein amino acid acylation GO:0043543 14 14 0,000 0,02217332 0,03940736 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,02217332 0,03936939 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,02217332 0,0393315 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,02217332 0,03929368 ! vesicle docking GO:0048278 14 14 0,000 0,02217332 0,03925593 ! superoxide metabolic process GO:0006801 15 14 0,000 0,02217332 0,03921826 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,02217332 0,03918066 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,02217332 0,03914313 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,02217332 0,03910567 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,02217332 0,03906829 ! hair cycle GO:0042633 14 14 0,000 0,02217332 0,03903097 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,02217332 0,03899373 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,02217332 0,03895656 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,02217332 0,03891946 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,02217332 0,03888242 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,02217332 0,03884546 ! lysosome organization GO:0007040 14 14 0,000 0,02217332 0,03880857 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,02217332 0,03877175 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,02217332 0,038735 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,02217332 0,03869832 ! primary neural tube formation GO:0014020 15 14 0,000 0,02217332 0,03866171 ! peptide cross-linking GO:0018149 14 14 0,000 0,02217332 0,03862517 ! regulation of behavior GO:0050795 14 14 0,000 0,02217332 0,03858869 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,02217332 0,03855229 ! base-excision repair GO:0006284 14 14 0,000 0,02217332 0,03851595 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,02217332 0,03847969 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,02217332 0,03844349 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,02217332 0,03840736 ! formation of primary germ layer GO:0001704 14 14 0,000 0,02217332 0,03837129 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,02217332 0,0383353 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,02217332 0,03829937 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,02217332 0,03826351 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,02217332 0,03822772 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,02217332 0,03819199 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,02217332 0,03815633 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,02217332 0,03812074 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,02217332 0,03808521 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,02217332 0,03804975 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,02217332 0,03801435 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,02373989 0,04066229 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,02373989 0,04062453 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,02373989 0,04058685 ! positive regulation of ossification GO:0045778 15 15 0,000 0,02373989 0,04054923 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,02373989 0,04051169 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,02373989 0,04047421 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,02373989 0,0404368 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,02373989 0,04039947 ! response to vitamin GO:0033273 15 15 0,000 0,02373989 0,0403622 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,02373989 0,040325 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,02373989 0,04028787 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,02373989 0,0402508 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,02373989 0,04021381 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,02373989 0,04017688 ! ovarian follicle development GO:0001541 15 15 0,000 0,02373989 0,04014002 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,02373989 0,04010323 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,02373989 0,0400665 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,02373989 0,04002985 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,02373989 0,03999326 ! heme metabolic process GO:0042168 15 15 0,000 0,02373989 0,03995673 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,02373989 0,03992028 ! chromosome condensation GO:0030261 15 15 0,000 0,02373989 0,03988389 ! response to starvation GO:0042594 15 15 0,000 0,02373989 0,03984756 ! response to ionizing radiation GO:0010212 16 15 0,000 0,02373989 0,0398113 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,02373989 0,03977511 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,02373989 0,03973899 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,02373989 0,03970292 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,02373989 0,03966693 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,02373989 0,039631 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,02373989 0,03959513 ! phospholipid transport GO:0015914 15 15 0,000 0,02373989 0,03955933 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,02373989 0,0395236 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,02373989 0,03948793 ! glutathione metabolic process GO:0006749 16 15 0,000 0,02373989 0,03945232 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,02373989 0,03941678 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,02373989 0,0393813 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,02373989 0,03934588 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,02373989 0,03931053 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,02373989 0,03927524 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,02373989 0,03924002 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,02373989 0,03920486 ! protein homooligomerization GO:0051260 15 15 0,000 0,02373989 0,03916976 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,02373989 0,03913473 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,02530418 0,04167615 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,02530418 0,04163894 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,02530418 0,04160179 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,02530418 0,04156472 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,02530418 0,0415277 ! learning GO:0007612 16 16 0,000 0,02530418 0,04149076 ! circadian rhythm GO:0007623 16 16 0,000 0,02530418 0,04145388 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,02530418 0,04141706 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,02530418 0,04138031 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,02530418 0,04134363 ! vacuole organization GO:0007033 16 16 0,000 0,02530418 0,04130701 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,02530418 0,04127045 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,02530418 0,04123396 ! vesicle targeting GO:0006903 17 16 0,000 0,02530418 0,04119754 ! segmentation GO:0035282 17 16 0,000 0,02530418 0,04116118 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,02530418 0,04112488 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,02530418 0,04108865 ! iron ion homeostasis GO:0055072 16 16 0,000 0,02530418 0,04105248 ! positive regulation of cell development GO:0010720 16 16 0,000 0,02530418 0,04101637 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,02530418 0,04098033 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,02530418 0,04094435 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,02530418 0,04090843 ! cell fate specification GO:0001708 16 16 0,000 0,02530418 0,04087258 ! fatty acid transport GO:0015908 16 16 0,000 0,02530418 0,04083679 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,02530418 0,04080106 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,02530418 0,0407654 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,02530418 0,04072979 ! cofactor catabolic process GO:0051187 16 16 0,000 0,02530418 0,04069425 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,02530418 0,04065877 ! polyol metabolic process GO:0019751 16 16 0,000 0,02530418 0,04062336 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,02530418 0,040588 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,02530418 0,04055271 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,02530418 0,04051747 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,02530418 0,0404823 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,02530418 0,04044719 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,02530418 0,04041214 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,02530418 0,04037715 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,02530418 0,04034223 ! regulation of coagulation GO:0050818 17 16 0,000 0,02530418 0,04030736 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,0268662 0,04275855 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,0268662 0,04272166 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,0268662 0,04268483 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,0268662 0,04264806 ! myelination GO:0042552 17 17 0,000 0,0268662 0,04261136 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,0268662 0,04257472 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,0268662 0,04253815 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,0268662 0,04250163 ! leukocyte adhesion GO:0007159 17 17 0,000 0,0268662 0,04246518 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,0268662 0,04242879 ! sensory perception of smell GO:0007608 17 17 0,000 0,0268662 0,04239247 ! glucose transport GO:0015758 17 17 0,000 0,0268662 0,0423562 ! cell junction assembly GO:0034329 18 17 0,000 0,0268662 0,04232 ! tissue remodeling GO:0048771 17 17 0,000 0,0268662 0,04228386 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,0268662 0,04224778 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,0268662 0,04221177 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,0268662 0,04217581 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,0268662 0,04213992 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,0268662 0,04210408 ! neural crest cell development GO:0014032 19 17 0,000 0,0268662 0,04206831 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,0268662 0,0420326 ! negative regulation of cell development GO:0010721 18 17 0,000 0,0268662 0,04199695 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,0268662 0,04196136 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,0268662 0,04192583 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,0268662 0,04189036 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,0268662 0,04185495 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,0268662 0,0418196 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,0268662 0,0417843 ! pigmentation GO:0043473 17 17 0,000 0,0268662 0,04174907 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,0268662 0,0417139 ! adult locomotory behavior GO:0008344 17 17 0,000 0,0268662 0,04167879 ! embryonic organ development GO:0048568 17 17 0,000 0,0268662 0,04164374 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,0268662 0,04160874 ! liver development GO:0001889 17 17 0,000 0,0268662 0,0415738 ! gene silencing GO:0016458 17 17 0,000 0,0268662 0,04153893 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,02842593 0,04391366 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,02842593 0,04387688 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,02842593 0,04384016 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,02842593 0,04380351 ! meiosis I GO:0007127 18 18 0,000 0,02842593 0,04376691 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,02842593 0,04373038 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,02842593 0,04369391 ! membrane docking GO:0022406 18 18 0,000 0,02842593 0,0436575 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,02842593 0,04362115 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,02842593 0,04358485 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,02842593 0,04354862 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,02842593 0,04351245 ! hexose transport GO:0008645 18 18 0,000 0,02842593 0,04347634 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,02842593 0,04344029 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,02842593 0,0434043 ! striated muscle contraction GO:0006941 18 18 0,000 0,02842593 0,04336837 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,02842593 0,0433325 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,02842593 0,04329669 ! ceramide metabolic process GO:0006672 18 18 0,000 0,02842593 0,04326094 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,02842593 0,04322524 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,02842593 0,04318961 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,02842593 0,04315403 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,02842593 0,04311851 ! B cell differentiation GO:0030183 18 18 0,000 0,02842593 0,04308306 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,02842593 0,04304765 ! ensheathment of neurons GO:0007272 18 18 0,000 0,02842593 0,04301231 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,02842593 0,04297703 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,02842593 0,0429418 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,02842593 0,04290663 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,02842593 0,04287152 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,02842593 0,04283646 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,0299834 0,04514657 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,0299834 0,04510972 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,0299834 0,04507292 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,0299834 0,04503619 ! glial cell differentiation GO:0010001 19 19 0,000 0,0299834 0,04499951 ! regulation of pH GO:0006885 19 19 0,000 0,0299834 0,0449629 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,0299834 0,04492634 ! feeding behavior GO:0007631 19 19 0,000 0,0299834 0,04488985 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,0299834 0,04485341 ! peroxisome organization GO:0007031 19 19 0,000 0,0299834 0,04481703 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,0299834 0,04478071 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,0299834 0,04474445 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,0299834 0,04470825 ! metanephros development GO:0001656 19 19 0,000 0,0299834 0,04467211 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,0299834 0,04463603 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,0299834 0,0446 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,0299834 0,04456403 ! peripheral nervous system development GO:0007422 19 19 0,000 0,0299834 0,04452812 ! regulation of protein stability GO:0031647 19 19 0,000 0,0299834 0,04449227 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,0299834 0,04445648 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,0299834 0,04442074 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,0299834 0,04438506 ! eye morphogenesis GO:0048592 19 19 0,000 0,0299834 0,04434944 ! regulation of cell shape GO:0008360 21 19 0,000 0,0299834 0,04431387 ! placenta development GO:0001890 19 19 0,000 0,0299834 0,04427837 ! response to heat GO:0009408 19 19 0,000 0,0299834 0,04424292 ! vesicle localization GO:0051648 20 19 0,000 0,0299834 0,04420752 ! regulation of muscle development GO:0048634 21 20 0,000 0,03153859 0,04646333 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,03153859 0,04642622 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,03153859 0,04638916 ! negative regulation of binding GO:0051100 21 20 0,000 0,03153859 0,04635217 ! organic ether metabolic process GO:0018904 20 20 0,000 0,03153859 0,04631524 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,03153859 0,04627836 ! neural tube development GO:0021915 21 20 0,000 0,03153859 0,04624155 ! nucleus organization GO:0006997 20 20 0,000 0,03153859 0,04620479 ! phagocytosis GO:0006909 21 20 0,000 0,03153859 0,04616809 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,03153859 0,04613145 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,03153859 0,04609486 ! protein targeting to membrane GO:0006612 22 20 0,000 0,03153859 0,04605834 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,03153859 0,04602187 ! chromatin remodeling GO:0006338 20 20 0,000 0,03153859 0,04598546 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,03153859 0,04594911 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,03153859 0,04591281 ! lipid oxidation GO:0034440 20 20 0,000 0,03153859 0,04587658 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,03153859 0,0458404 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,03153859 0,04580427 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,03153859 0,04576821 ! RNA modification GO:0009451 20 20 0,000 0,03153859 0,0457322 ! single fertilization GO:0007338 21 20 0,000 0,03153859 0,04569624 ! regulation of B cell activation GO:0050864 20 20 0,000 0,03153859 0,04566035 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,03309152 0,04787101 ! mRNA catabolic process GO:0006402 21 21 0,000 0,03309152 0,04783346 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,03309152 0,04779598 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,03309152 0,04775855 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,03309152 0,04772118 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,03309152 0,04768387 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,03309152 0,04764661 ! Notch signaling pathway GO:0007219 22 21 0,000 0,03309152 0,04760942 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,03309152 0,04757228 ! ear morphogenesis GO:0042471 21 21 0,000 0,03309152 0,0475352 ! organic anion transport GO:0015711 21 21 0,000 0,03309152 0,04749818 ! cholesterol transport GO:0030301 21 21 0,000 0,03309152 0,04746122 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,03309152 0,04742431 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,03309152 0,04738746 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,03309152 0,04735067 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,03309152 0,04731394 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,03309152 0,04727726 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,03309152 0,04724064 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,03309152 0,04720408 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,03309152 0,04716757 ! regulation of proteolysis GO:0030162 21 21 0,000 0,03309152 0,04713112 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,03309152 0,04709472 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,03309152 0,04705838 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,03309152 0,0470221 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,03309152 0,04698588 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,03464218 0,04914976 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,03464218 0,04911195 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,03464218 0,0490742 ! sister chromatid segregation GO:0000819 22 22 0,000 0,03464218 0,04903651 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,03464218 0,04899888 ! regulation of ion transport GO:0043269 22 22 0,000 0,03464218 0,0489613 ! odontogenesis GO:0042476 22 22 0,000 0,03464218 0,04892378 ! cell junction organization GO:0034330 23 22 0,000 0,03464218 0,04888632 ! hormone-mediated signaling GO:0009755 22 22 0,000 0,03464218 0,04884892 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,03464218 0,04881157 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,03464218 0,04877428 ! ovulation cycle process GO:0022602 22 22 0,000 0,03464218 0,04873705 ! spindle organization GO:0007051 22 22 0,000 0,03464218 0,04869988 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,03464218 0,04866276 ! cell chemotaxis GO:0060326 23 22 0,000 0,03464218 0,04862569 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,03464218 0,04858869 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,03464218 0,04855174 ! male sex differentiation GO:0046661 22 22 0,000 0,03464218 0,04851485 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,03464218 0,04847801 ! biopolymer methylation GO:0043414 22 22 0,000 0,03464218 0,04844123 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,03464218 0,0484045 ! detection of external stimulus GO:0009581 23 22 0,000 0,03464218 0,04836783 ! neuron migration GO:0001764 22 22 0,000 0,03464218 0,04833122 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,03464218 0,04829466 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,03464218 0,04825815 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,03464218 0,0482217 ! aerobic respiration GO:0009060 22 22 0,000 0,03464218 0,04818531 ! cytokine production GO:0001816 22 22 0,000 0,03464218 0,04814897 ! cytokinesis GO:0000910 23 22 0,000 0,03464218 0,04811269 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,03619058 0,05022533 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,03619058 0,05018754 ! viral infectious cycle GO:0019058 23 23 0,000 0,03619058 0,0501498 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,03619058 0,05011213 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,03619058 0,0500745 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,03619058 0,05003694 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,03619058 0,04999943 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,03619058 0,04996198 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,03619058 0,04992458 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,03619058 0,04988724 ! endocrine system development GO:0035270 23 23 0,000 0,03619058 0,04984996 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,03619058 0,04981273 ! positive regulation of growth GO:0045927 23 23 0,000 0,03619058 0,04977555 ! female gonad development GO:0008585 23 23 0,000 0,03619058 0,04973843 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,03619058 0,04970137 ! lipid homeostasis GO:0055088 23 23 0,000 0,03619058 0,04966436 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,03619058 0,04962741 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,03619058 0,04959051 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,03619058 0,04955367 ! cell projection assembly GO:0030031 25 23 0,000 0,03619058 0,04951688 ! mitochondrial transport GO:0006839 24 24 0,000 0,03773672 0,05159405 ! regulation of action potential GO:0001508 24 24 0,000 0,03773672 0,05155581 ! gliogenesis GO:0042063 24 24 0,000 0,03773672 0,05151762 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,03773672 0,05147948 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,03773672 0,05144141 ! glucose homeostasis GO:0042593 24 24 0,000 0,03773672 0,05140339 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,03773672 0,05136542 ! T cell differentiation GO:0030217 24 24 0,000 0,03773672 0,05132751 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,03773672 0,05128966 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,03773672 0,05125187 ! ovulation cycle GO:0042698 24 24 0,000 0,03773672 0,05121413 ! fertilization GO:0009566 25 24 0,000 0,03773672 0,05117644 ! maintenance of protein location GO:0045185 25 24 0,000 0,03773672 0,05113881 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,03773672 0,05110124 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,03773672 0,05106372 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,03773672 0,05102625 ! glucan metabolic process GO:0044042 25 24 0,000 0,03773672 0,05098884 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,03928061 0,05303602 ! negative regulation of secretion GO:0051048 26 25 0,000 0,03928061 0,05299719 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,03928061 0,05295843 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,03928061 0,05291971 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,03928061 0,05288106 ! cellular component disassembly GO:0022411 26 25 0,000 0,03928061 0,05284246 ! endosome transport GO:0016197 25 25 0,000 0,03928061 0,05280392 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,03928061 0,05276543 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,03928061 0,052727 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,03928061 0,05268862 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,03928061 0,0526503 ! excretion GO:0007588 25 25 0,000 0,03928061 0,05261204 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,03928061 0,05257383 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,03928061 0,05253568 ! gastrulation GO:0007369 25 25 0,000 0,03928061 0,05249758 ! heart morphogenesis GO:0003007 25 25 0,000 0,03928061 0,05245954 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,03928061 0,05242156 ! regulation of endocytosis GO:0030100 25 25 0,000 0,03928061 0,05238362 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,03928061 0,05234575 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,03928061 0,05230792 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,03928061 0,05227016 ! positive regulation of binding GO:0051099 27 26 0,000 0,04082225 0,0542824 ! positive regulation of defense response GO:0031349 26 26 0,000 0,04082225 0,05424326 ! glycolysis GO:0006096 26 26 0,000 0,04082225 0,05420418 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,04082225 0,05416516 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,04082225 0,05412619 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,04082225 0,05408728 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,04082225 0,05404842 ! cellular defense response GO:0006968 26 26 0,000 0,04082225 0,05400962 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,04082225 0,05397088 ! double-strand break repair GO:0006302 27 26 0,000 0,04082225 0,05393219 ! regulation of protein secretion GO:0050708 26 26 0,000 0,04082225 0,05389355 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,04082225 0,05385498 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,04082225 0,05381645 ! response to insulin stimulus GO:0032868 28 26 0,000 0,04082225 0,05377799 ! maintenance of location in cell GO:0051651 27 26 0,000 0,04082225 0,05373957 ! synapse organization GO:0050808 26 26 0,000 0,04082225 0,05370122 ! chloride transport GO:0006821 27 27 0,000 0,04236163 0,05568651 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,04236163 0,05564682 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,04236163 0,05560719 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,04236163 0,05556761 ! learning or memory GO:0007611 28 27 0,000 0,04236163 0,05552809 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,04236163 0,05548862 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,04236163 0,05544921 ! peptide metabolic process GO:0006518 29 27 0,000 0,04236163 0,05540986 ! activation of caspase activity GO:0006919 27 27 0,000 0,04236163 0,05537056 ! mesenchymal cell development GO:0014031 29 27 0,000 0,04236163 0,05533132 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,04236163 0,05529213 ! defense response to bacterium GO:0042742 27 27 0,000 0,04236163 0,055253 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,04236163 0,05521393 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,04236163 0,05517491 ! cell growth GO:0016049 27 27 0,000 0,04236163 0,05513594 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,04389877 0,05709629 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,04389877 0,05705602 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,04389877 0,05701581 ! carbohydrate transport GO:0008643 28 28 0,000 0,04389877 0,05697566 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,04389877 0,05693557 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,04389877 0,05689553 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,04389877 0,05685555 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,04389877 0,05681562 ! histone modification GO:0016570 28 28 0,000 0,04389877 0,05677575 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,04389877 0,05673593 ! developmental growth GO:0048589 28 28 0,000 0,04389877 0,05669617 ! cartilage development GO:0051216 29 28 0,000 0,04389877 0,05665647 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,04543367 0,0585964 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,04543367 0,05855542 ! viral reproductive process GO:0022415 29 29 0,000 0,04543367 0,0585145 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,04543367 0,05847364 ! leukocyte migration GO:0050900 30 29 0,000 0,04543367 0,05843284 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,04543367 0,05839209 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,04543367 0,0583514 ! antigen processing and presentation GO:0019882 29 29 0,000 0,04543367 0,05831076 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,04543367 0,05827019 ! tRNA processing GO:0008033 29 29 0,000 0,04543367 0,05822966 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,04543367 0,0581892 ! covalent chromatin modification GO:0016569 29 29 0,000 0,04543367 0,05814879 ! adult behavior GO:0030534 30 29 0,000 0,04543367 0,05810844 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,04543367 0,05806814 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,04543367 0,0580279 ! response to UV GO:0009411 29 29 0,000 0,04543367 0,05798771 ! transition metal ion transport GO:0000041 31 30 0,000 0,04696633 0,05990238 ! RNA catabolic process GO:0006401 30 30 0,000 0,04696633 0,05986096 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,04696633 0,05981959 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,04696633 0,05977828 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,04696633 0,05973702 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,04696633 0,05969582 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,04696633 0,05965468 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,04696633 0,0596136 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,04696633 0,05957257 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,04696633 0,0595316 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,04696633 0,05949068 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,04696633 0,05944982 ! response to temperature stimulus GO:0009266 30 30 0,000 0,04696633 0,05940902 ! regulation of ossification GO:0030278 30 30 0,000 0,04696633 0,05936827 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,04696633 0,05932758 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,04696633 0,05928695 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,04696633 0,05924637 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,04696633 0,05920584 ! vesicle organization GO:0016050 30 30 0,000 0,04696633 0,05916537 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,04696633 0,05912496 ! establishment of organelle localization GO:0051656 31 30 0,000 0,04696633 0,0590846 ! regulation of translational initiation GO:0006446 31 31 0,000 0,04849675 0,06096828 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,04849675 0,06092672 ! membrane fusion GO:0006944 31 31 0,000 0,04849675 0,06088522 ! B cell activation GO:0042113 31 31 0,000 0,04849675 0,06084377 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,04849675 0,06080238 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,04849675 0,06076105 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,04849675 0,06071977 ! ion transmembrane transport GO:0034220 31 31 0,000 0,04849675 0,06067855 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,04849675 0,06063738 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,04849675 0,06059627 ! digestion GO:0007586 31 31 0,000 0,04849675 0,06055522 ! regulation of DNA replication GO:0006275 32 31 0,000 0,04849675 0,06051422 ! regulation of heart contraction GO:0008016 31 31 0,000 0,04849675 0,06047328 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,04849675 0,06043239 ! camera-type eye development GO:0043010 31 31 0,000 0,04849675 0,06039156 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,04849675 0,06035078 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,04849675 0,06031006 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,04849675 0,06026939 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,04849675 0,06022878 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,05002493 0,06208481 ! cell redox homeostasis GO:0045454 32 32 0,000 0,05002493 0,06204303 ! muscle fiber development GO:0048747 32 32 0,000 0,05002493 0,06200131 ! glucose catabolic process GO:0006007 32 32 0,000 0,05002493 0,06195964 ! lipid modification GO:0030258 32 32 0,000 0,05002493 0,06191803 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,05002493 0,06187648 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,05002493 0,06183498 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,05002493 0,06179353 ! cell maturation GO:0048469 32 32 0,000 0,05002493 0,06175214 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,05002493 0,06171081 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,05002493 0,06166953 ! nuclear export GO:0051168 32 32 0,000 0,05002493 0,06162831 ! kidney development GO:0001822 32 32 0,000 0,05002493 0,06158714 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,05002493 0,06154603 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,05002493 0,06150497 ! maintenance of location GO:0051235 33 32 0,000 0,05002493 0,06146397 ! negative regulation of cell size GO:0045792 33 33 0,000 0,05155088 0,06329666 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,05155088 0,06325451 ! amino acid transport GO:0006865 33 33 0,000 0,05155088 0,06321243 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,05155088 0,0631704 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,05155088 0,06312843 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,05155088 0,06308651 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,05155088 0,06304464 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,05155088 0,06300284 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,05155088 0,06296109 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,05155088 0,06291939 ! regulation of actin filament length GO:0030832 34 34 0,000 0,05307461 0,06473627 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,05307461 0,06469345 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,05307461 0,0646507 ! response to metal ion GO:0010038 34 34 0,000 0,05307461 0,06460799 ! ear development GO:0043583 34 34 0,000 0,05307461 0,06456535 ! muscle cell differentiation GO:0042692 35 34 0,000 0,05307461 0,06452276 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,05307461 0,06448023 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,05307461 0,06443775 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,05307461 0,06439533 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,05307461 0,06435296 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,05307461 0,06431065 ! secondary metabolic process GO:0019748 34 34 0,000 0,05307461 0,0642684 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,05307461 0,0642262 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,05307461 0,06418406 ! viral reproduction GO:0016032 34 34 0,000 0,05307461 0,06414197 ! detection of stimulus GO:0051606 36 34 0,000 0,05307461 0,06409994 ! acute inflammatory response GO:0002526 35 35 0,000 0,05459611 0,06589432 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,05459611 0,06585119 ! regulation of cellular component size GO:0032535 35 35 0,000 0,05459611 0,06580813 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,05459611 0,06576511 ! mesoderm development GO:0007498 35 35 0,000 0,05459611 0,06572216 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,05459611 0,06567926 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,05459611 0,06563642 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,05459611 0,06559363 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,05459611 0,0655509 ! inorganic anion transport GO:0015698 35 35 0,000 0,05459611 0,06550822 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,05459611 0,0654656 ! regulation of immune effector process GO:0002697 35 35 0,000 0,05459611 0,06542303 ! hydrogen transport GO:0006818 36 36 0,000 0,05611538 0,0671999 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,05611538 0,06715627 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,05611538 0,06711269 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,05611538 0,06706916 ! regulation of mitosis GO:0007088 37 36 0,000 0,05611538 0,0670257 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,05611538 0,06698229 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,05611538 0,06693893 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,05611538 0,06689563 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,05611538 0,06685239 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,05611538 0,06680921 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,05611538 0,06676608 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,05611538 0,066723 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,05611538 0,06667998 ! gonad development GO:0008406 36 36 0,000 0,05611538 0,06663702 ! regulation of lipase activity GO:0060191 36 36 0,000 0,05611538 0,06659411 ! activation of immune response GO:0002253 36 36 0,000 0,05611538 0,06655126 ! coagulation GO:0050817 39 36 0,000 0,05611538 0,06650846 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,05763244 0,06826259 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,05763244 0,06821874 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,05763244 0,06817496 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,05763244 0,06813123 ! response to drug GO:0042493 37 37 0,000 0,05763244 0,06808755 ! lung development GO:0030324 38 37 0,000 0,05763244 0,06804394 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,05763244 0,06800037 ! eye development GO:0001654 37 37 0,000 0,05763244 0,06795687 ! negative regulation of growth GO:0045926 37 37 0,000 0,05763244 0,06791342 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,05763244 0,06787002 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,05763244 0,06782668 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,05763244 0,0677834 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,05763244 0,06774017 ! adaptive immune response GO:0002250 37 37 0,000 0,05763244 0,06769699 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,05914728 0,06943212 ! neurotransmitter transport GO:0006836 40 38 0,000 0,05914728 0,06938793 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,05914728 0,06934379 ! exocytosis GO:0006887 40 38 0,000 0,05914728 0,0692997 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,05914728 0,06925568 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,05914728 0,0692117 ! chromosome segregation GO:0007059 38 38 0,000 0,05914728 0,06916779 ! urogenital system development GO:0001655 38 38 0,000 0,05914728 0,06912393 ! hexose catabolic process GO:0019320 38 38 0,000 0,05914728 0,06908012 ! RNA elongation GO:0006354 38 38 0,000 0,05914728 0,06903637 ! meiotic cell cycle GO:0051321 38 38 0,000 0,05914728 0,06899268 ! axon guidance GO:0007411 39 38 0,000 0,05914728 0,06894904 ! regulation of neurological system process GO:0031644 38 38 0,000 0,05914728 0,06890546 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,05914728 0,06886193 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,05914728 0,06881846 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,0606599 0,07053388 ! hemostasis GO:0007599 42 39 0,000 0,0606599 0,07048941 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,0606599 0,07044499 ! activation of MAPK activity GO:0000187 39 39 0,000 0,0606599 0,07040063 ! respiratory tube development GO:0030323 40 39 0,000 0,0606599 0,07035633 ! response to unfolded protein GO:0006986 39 39 0,000 0,0606599 0,07031208 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,0606599 0,07026788 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,0606599 0,07022374 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,0606599 0,07017966 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,0606599 0,07013563 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,0606599 0,07009166 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,0606599 0,07004775 ! respiratory system development GO:0060541 40 39 0,000 0,0606599 0,07000388 ! developmental maturation GO:0021700 39 39 0,000 0,0606599 0,06996008 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,0606599 0,06991632 ! limb development GO:0060173 39 39 0,000 0,0606599 0,06987263 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,0606599 0,06982898 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,0606599 0,06978539 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,06217032 0,07147841 ! DNA catabolic process GO:0006308 41 40 0,000 0,06217032 0,07143385 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,06217032 0,07138934 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,06217032 0,07134489 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,06217032 0,07130049 ! organelle localization GO:0051640 41 40 0,000 0,06217032 0,07125615 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,06367852 0,07293941 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,06367852 0,07289411 ! amine catabolic process GO:0009310 42 41 0,000 0,06367852 0,07284886 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,06367852 0,07280367 ! regulation of caspase activity GO:0043281 41 41 0,000 0,06367852 0,07275853 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,06367852 0,07271346 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,06367852 0,07266843 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,06367852 0,07262346 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,06367852 0,07257855 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,06518452 0,07424912 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,06518452 0,07420326 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,06518452 0,07415745 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,06518452 0,07411171 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,06518452 0,07406601 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,06518452 0,07402038 ! protein ubiquitination GO:0016567 43 42 0,000 0,06518452 0,0739748 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,06518452 0,07392928 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,06518452 0,07388381 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,06518452 0,0738384 ! reproductive structure development GO:0048608 43 43 0,000 0,06668832 0,07549544 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,06668832 0,07544909 ! mitochondrion organization GO:0007005 44 43 0,000 0,06668832 0,07540281 ! alcohol catabolic process GO:0046164 43 43 0,000 0,06668832 0,07535658 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,06668832 0,0753104 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,06668832 0,07526428 ! humoral immune response GO:0006959 44 44 0,000 0,06818992 0,07691189 ! mRNA transport GO:0051028 44 44 0,000 0,06818992 0,07686484 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,06818992 0,07681786 ! vitamin metabolic process GO:0006766 44 44 0,000 0,06818992 0,07677094 ! amine biosynthetic process GO:0009309 46 45 0,000 0,06968932 0,07841112 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,06968932 0,07836328 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,06968932 0,0783155 ! regulation of DNA binding GO:0051101 47 45 0,000 0,06968932 0,07826777 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,06968932 0,07822011 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,06968932 0,0781725 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,06968932 0,07812495 ! protein processing GO:0016485 45 45 0,000 0,06968932 0,07807746 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,07118653 0,07970642 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,07118653 0,07965803 ! tube morphogenesis GO:0035239 47 46 0,000 0,07118653 0,07960969 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,07118653 0,07956141 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,07118653 0,0795132 ! regulation of membrane potential GO:0042391 46 46 0,000 0,07118653 0,07946504 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,07268155 0,0810848 ! regulation of blood pressure GO:0008217 48 47 0,000 0,07268155 0,08103575 ! sex differentiation GO:0007548 47 47 0,000 0,07268155 0,08098675 ! amine transport GO:0015837 47 47 0,000 0,07268155 0,08093782 ! rhythmic process GO:0048511 47 47 0,000 0,07268155 0,08088894 ! regulation of catabolic process GO:0009894 48 47 0,000 0,07268155 0,08084013 ! calcium ion transport GO:0006816 48 48 0,000 0,07417438 0,08245077 ! actin filament organization GO:0007015 50 48 0,000 0,07417438 0,08240107 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,07417438 0,08235143 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,07417438 0,08230185 ! DNA recombination GO:0006310 48 48 0,000 0,07417438 0,08225233 ! leukocyte differentiation GO:0002521 50 49 0,000 0,07566502 0,08385486 ! gland development GO:0048732 51 49 0,000 0,07566502 0,08380447 ! cell cycle arrest GO:0007050 49 49 0,000 0,07566502 0,08375413 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,07566502 0,08370386 ! divalent metal ion transport GO:0070838 49 49 0,000 0,07566502 0,08365365 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,07566502 0,0836035 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,07566502 0,0835534 ! response to bacterium GO:0009617 50 49 0,000 0,07566502 0,08350337 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,07566502 0,0834534 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,07566502 0,08340349 ! regulation of defense response GO:0031347 50 50 0,000 0,07715348 0,08499335 ! negative regulation of transport GO:0051051 51 50 0,000 0,07715348 0,08494257 ! chromatin assembly GO:0031497 50 50 0,000 0,07715348 0,08489186 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,07715348 0,08484121 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,07715348 0,08479062 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,07715348 0,08474009 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,07715348 0,08468962 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,07715348 0,08463921 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,07715348 0,08458886 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,07863976 0,08616711 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,07863976 0,08611592 ! positive regulation of immune response GO:0050778 51 51 0,000 0,07863976 0,08606478 ! rRNA metabolic process GO:0016072 51 51 0,000 0,07863976 0,0860137 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,07863976 0,08596268 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,07863976 0,08591173 ! protein maturation GO:0051604 51 51 0,000 0,07863976 0,08586083 ! RNA localization GO:0006403 52 52 0,000 0,08012387 0,08742942 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,08012387 0,08737769 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,08012387 0,08732602 ! cell fate commitment GO:0045165 52 52 0,000 0,08012387 0,08727441 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,08012387 0,08722286 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,08012387 0,08717137 ! response to light stimulus GO:0009416 53 52 0,000 0,08012387 0,08711994 ! sodium ion transport GO:0006814 53 53 0,000 0,0816058 0,08867895 ! tRNA metabolic process GO:0006399 53 53 0,000 0,0816058 0,08862669 ! response to hypoxia GO:0001666 53 53 0,000 0,0816058 0,0885745 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,0816058 0,08852236 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,0816058 0,08847029 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,0816058 0,08841828 ! regulation of protein transport GO:0051223 53 53 0,000 0,0816058 0,08836633 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,08308557 0,08991585 ! response to oxygen levels GO:0070482 55 54 0,000 0,08308557 0,08986309 ! response to virus GO:0009615 54 54 0,000 0,08308557 0,08981038 ! hormone metabolic process GO:0042445 55 54 0,000 0,08308557 0,08975774 ! sulfur metabolic process GO:0006790 55 54 0,000 0,08308557 0,08970515 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,08308557 0,08965263 ! nucleosome organization GO:0034728 55 55 0,000 0,08456316 0,09119362 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,08456316 0,0911403 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,08456316 0,09108703 ! in utero embryonic development GO:0001701 55 55 0,000 0,08456316 0,09103382 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,08456316 0,09098068 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,08456316 0,0909276 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,08603859 0,09246013 ! reproductive developmental process GO:0003006 56 56 0,000 0,08603859 0,09240625 ! regulation of nervous system development GO:0051960 57 56 0,000 0,08603859 0,09235243 ! regulation of binding GO:0051098 60 57 0,000 0,08751186 0,09387913 ! ATP metabolic process GO:0046034 57 57 0,000 0,08751186 0,09382452 ! regulation of protein localization GO:0032880 58 57 0,000 0,08751186 0,09376997 ! innate immune response GO:0045087 58 58 0,000 0,08898297 0,09529088 ! dephosphorylation GO:0016311 60 59 0,000 0,09045192 0,09680771 ! carboxylic acid transport GO:0046942 59 59 0,000 0,09045192 0,09675153 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,09045192 0,09669541 ! regulation of cell development GO:0060284 60 59 0,000 0,09045192 0,09663935 ! sterol metabolic process GO:0016125 59 59 0,000 0,09045192 0,09658336 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,09045192 0,09652744 ! immune effector process GO:0002252 59 59 0,000 0,09045192 0,09647158 ! potassium ion transport GO:0006813 60 60 0,000 0,09191871 0,09797929 ! protein polymerization GO:0051258 65 60 0,000 0,09191871 0,09792265 ! cellular respiration GO:0045333 62 61 0,000 0,09338336 0,0994255 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,09338336 0,09936809 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,09338336 0,09931075 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,09338336 0,09925348 ! lipid transport GO:0006869 62 62 0,000 0,09484586 0,10074981 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,09484586 0,10069178 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,09484586 0,10063381 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,09484586 0,1005759 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,09484586 0,10051807 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,09484586 0,1004603 ! regulation of secretion GO:0051046 65 63 0,000 0,09630622 0,10194851 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,09630622 0,10188999 ! glucose metabolic process GO:0006006 63 63 0,000 0,09630622 0,10183153 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,09630622 0,10177314 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,09630622 0,10171482 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,09776443 0,10319578 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,09776443 0,10313671 ! angiogenesis GO:0001525 65 64 0,000 0,09776443 0,10307771 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,09776443 0,10301878 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,09776443 0,10295991 ! anion transport GO:0006820 65 65 0,000 0,0992205 0,10443368 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,0992205 0,10437408 ! regulation of hormone levels GO:0010817 66 65 0,000 0,0992205 0,10431454 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,10067444 0,10578277 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! DNA packaging GO:0006323 66 66 0,000 0,10067444 0,1057225 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,10067444 0,10566229 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,10067444 0,10560215 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,10212624 0,10706408 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,10212624 0,10700322 ! muscle contraction GO:0006936 67 67 0,000 0,10212624 0,10694242 ! striated muscle tissue development GO:0014706 69 67 0,000 0,10212624 0,10688169 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,10212624 0,10682103 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,10212624 0,10676044 ! response to radiation GO:0009314 70 68 0,000 0,10357591 0,10821451 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,10357591 0,1081532 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,10357591 0,10809196 ! regulation of cell size GO:0008361 68 68 0,000 0,10357591 0,10803079 ! sensory perception of sound GO:0007605 71 69 0,000 0,10502345 0,10947863 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,10502345 0,10941675 ! response to nutrient levels GO:0031667 69 69 0,000 0,10502345 0,10935493 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,10502345 0,10929318 ! positive regulation of transport GO:0051050 71 70 0,000 0,10646887 0,11073484 ! cell part morphogenesis GO:0032990 75 70 0,000 0,10646887 0,11067238 ! wound healing GO:0042060 74 70 0,000 0,10646887 0,11060999 ! growth GO:0040007 70 70 0,000 0,10646887 0,11054768 ! muscle tissue development GO:0060537 72 70 0,000 0,10646887 0,11048543 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,10646887 0,11042326 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,10791217 0,11185721 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,10791217 0,11179434 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,10791217 0,11173153 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,10791217 0,11166879 ! secretion by cell GO:0032940 75 72 0,000 0,10935334 0,11309664 ! muscle system process GO:0003012 72 72 0,000 0,10935334 0,11303321 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,10935334 0,11296985 ! sensory organ development GO:0007423 72 72 0,000 0,10935334 0,11290656 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,10935334 0,11284334 ! regulation of cytokine production GO:0001817 72 72 0,000 0,10935334 0,1127802 ! electron transport chain GO:0022900 75 74 0,000 0,11222935 0,11568159 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,11222935 0,11561693 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,11366418 0,11702966 ! response to oxidative stress GO:0006979 76 75 0,000 0,11366418 0,11696431 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,11366418 0,11689904 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,11509691 0,11830652 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,11652752 0,11971027 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,11652752 0,11964358 ! regulation of protein modification process GO:0031399 79 78 0,000 0,11795604 0,12104286 ! microtubule-based movement GO:0007018 82 78 0,000 0,11795604 0,12097551 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,11795604 0,12090822 ! metal ion homeostasis GO:0055065 78 78 0,000 0,11795604 0,12084101 ! regulation of immune response GO:0050776 78 78 0,000 0,11795604 0,12077388 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,12080678 0,12362404 ! neuron projection development GO:0031175 85 80 0,000 0,12080678 0,12355543 ! MAPKKK cascade GO:0000165 82 81 0,000 0,122229 0,12494068 ! tube development GO:0035295 83 81 0,000 0,122229 0,12487142 ! lymphocyte activation GO:0046649 82 81 0,000 0,122229 0,12480224 ! lipid catabolic process GO:0016042 82 81 0,000 0,122229 0,12473314 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,12506718 0,12755883 ! ncRNA processing GO:0034470 83 83 0,000 0,12506718 0,12748828 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,12506718 0,1274178 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,12648313 0,12878918 ! regulation of cellular localization GO:0060341 86 85 0,000 0,12789701 0,13015692 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,12789701 0,13008509 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,1293088 0,13144849 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,1293088 0,13137603 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,1293088 0,13130365 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,1293088 0,13123134 ! heart development GO:0007507 90 87 0,000 0,13071852 0,13258901 ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,13212615 0,13394307 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,13212615 0,13386944 ! chemotaxis GO:0006935 90 89 0,000 0,13353172 0,13521921 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,13353172 0,13514496 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,13493522 0,13649046 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,13633665 0,13783239 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,13633665 0,13775682 ! visual perception GO:0007601 93 92 0,000 0,13773602 0,13909451 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,13773602 0,13901833 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,13773602 0,13894224 ! tissue morphogenesis GO:0048729 94 93 0,000 0,13913332 0,14027501 ! regulation of response to stress GO:0080134 97 94 0,000 0,14052857 0,14160424 ! blood vessel development GO:0001568 95 94 0,000 0,14052857 0,14152686 ! pattern specification process GO:0007389 96 94 0,000 0,14052857 0,14144956 ! epidermis development GO:0008544 94 94 0,000 0,14052857 0,14137235 ! cofactor metabolic process GO:0051186 95 94 0,000 0,14052857 0,14129523 ! vasculature development GO:0001944 97 96 0,000 0,14331289 0,14401617 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,14608902 0,14672592 ! blood circulation GO:0008015 99 98 0,000 0,14608902 0,146646 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,14608902 0,14656617 ! ectoderm development GO:0007398 99 99 0,000 0,14747401 0,14787519 ! response to hormone stimulus GO:0009725 102 100 0,000 0,14885696 0,14918074 ! muscle organ development GO:0007517 102 100 0,000 0,14885696 0,14909966 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,14885696 0,14901867 ! response to other organism GO:0051707 101 100 0,000 0,14885696 0,14893777 ! hemopoiesis GO:0030097 104 100 0,000 0,14885696 0,14885696