pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/333-4-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear localization sequence binding GO:0008139 8 7 3,000 1,02E-10 3,721E-07 ! signal sequence binding GO:0005048 18 17 3,000 6,871E-09 1,253E-05 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 2,000 6,74E-07 8,195E-04 ! nuclear pore GO:0005643 79 62 3,000 1,544E-06 1,408E-03 ! protein import into nucleus GO:0006606 73 66 3,000 1,987E-06 1,45E-03 ! nuclear import GO:0051170 74 67 3,000 2,111E-06 1,284E-03 ! regulation of DNA recombination GO:0000018 38 19 2,000 2,271E-06 1,183E-03 ! protein localization in nucleus GO:0034504 78 71 3,000 2,666E-06 1,216E-03 ! pore complex GO:0046930 89 72 3,000 2,82E-06 1,143E-03 ! protein transporter activity GO:0008565 80 73 3,000 2,981E-06 1,087E-03 ! interphase of mitotic cell cycle GO:0051329 100 81 3,000 4,523E-06 1,5E-03 ! interphase GO:0051325 103 83 3,000 4,986E-06 1,516E-03 ! protein import GO:0017038 102 93 3,000 7,848E-06 2,202E-03 ! protein localization in organelle GO:0033365 104 95 3,000 8,541E-06 2,225E-03 ! mRNA stabilization GO:0048255 6 5 1,000 1,85E-05 4,5E-03 GO:0043489|RNA stabilization, ! insulin-like growth factor I binding GO:0031994 6 5 1,000 1,85E-05 4,218E-03 ! G2 phase GO:0051319 6 5 1,000 1,85E-05 3,97E-03 GO:0000085|G2 phase of mitotic cell cycle, ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 1,85E-05 3,75E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 2,773E-05 5,324E-03 ! nucleoside catabolic process GO:0009164 7 6 1,000 2,773E-05 5,058E-03 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 1,000 3,879E-05 6,738E-03 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 1,000 5,167E-05 8,568E-03 ! regulation of smooth muscle cell migration GO:0014910 11 8 1,000 5,167E-05 8,196E-03 ! NAD biosynthetic process GO:0009435 9 8 1,000 5,167E-05 7,854E-03 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 1,000 6,638E-05 9,686E-03 ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 1,000 6,638E-05 9,313E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 1,000 6,638E-05 8,968E-03 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 1,000 6,638E-05 8,648E-03 ! mRNA polyadenylation GO:0006378 10 9 1,000 6,638E-05 8,35E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 2,000 8,519E-05 0,01035903 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 2,000 9,812E-05 0,01154622 ! regulation of RNA stability GO:0043487 13 11 1,000 1,012E-04 0,0115412 GO:0043488|regulation of mRNA stability, ! mRNA 3'-end processing GO:0031124 12 11 1,000 1,012E-04 0,01119146 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 1,000 1,012E-04 0,0108623 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 2,000 1,074E-04 0,0111952 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 2,000 1,123E-04 0,01137608 ! RNA polyadenylation GO:0043631 13 12 1,000 1,214E-04 0,01196766 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 1,000 1,214E-04 0,01165272 ! midbody GO:0030496 14 12 1,000 1,214E-04 0,01135393 ! positive regulation of ligase activity GO:0051351 86 70 2,000 1,224E-04 0,01116256 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 2,000 1,503E-04 0,01337212 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 1,000 1,671E-04 0,01451165 ! nucleoside kinase activity GO:0019206 17 14 1,000 1,671E-04 0,01417417 ! regulation of alpha-beta T cell activation GO:0046634 15 14 1,000 1,671E-04 0,01385203 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 1,000 1,671E-04 0,01354421 ! regulation of ligase activity GO:0051340 95 78 2,000 1,689E-04 0,0133909 ! NAD metabolic process GO:0019674 17 15 1,000 1,926E-04 0,01495013 ! RNA 3'-end processing GO:0031123 16 15 1,000 1,926E-04 0,01463867 ! protein import into nucleus, docking GO:0000059 15 15 1,000 1,926E-04 0,01433992 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 2,000 2,03E-04 0,01481073 GO:0010498|proteasomal protein catabolic process, ! regulation of DNA metabolic process GO:0051052 139 84 2,000 2,103E-04 0,01504426 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 1,000 2,199E-04 0,0154298 ! spindle microtubule GO:0005876 27 18 1,000 2,799E-04 0,01926886 ! positive regulation of T cell differentiation GO:0045582 28 18 1,000 2,799E-04 0,01891203 ! transcription factor TFIID complex GO:0005669 19 18 1,000 2,799E-04 0,01856817 ! negative regulation of translation GO:0017148 31 18 1,000 2,799E-04 0,0182366 ! cellular response to unfolded protein GO:0034620 21 19 1,000 3,126E-04 0,0200074 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of lymphocyte differentiation GO:0045621 30 20 1,000 3,471E-04 0,02182851 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 1,000 3,833E-04 0,02369708 ! purine ribonucleoside metabolic process GO:0046128 24 22 1,000 4,212E-04 0,02561046 GO:0042278|purine nucleoside metabolic process, ! vitamin biosynthetic process GO:0009110 25 23 1,000 4,609E-04 0,02756617 ! insulin-like growth factor binding GO:0005520 27 23 1,000 4,609E-04 0,02712155 ! phosphate binding GO:0042301 25 23 1,000 4,609E-04 0,02669105 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 1,000 5,906E-04 0,03366484 ! response to endoplasmic reticulum stress GO:0034976 30 26 1,000 5,906E-04 0,03314692 ! fat cell differentiation GO:0045444 30 27 1,000 6,373E-04 0,03522618 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 6,373E-04 0,03470042 ! nicotinamide metabolic process GO:0006769 32 28 1,000 6,858E-04 0,03678871 GO:0046496|nicotinamide nucleotide metabolic process, ! alkaloid metabolic process GO:0009820 33 29 1,000 7,359E-04 0,03890791 ! ER-nuclear signaling pathway GO:0006984 32 29 1,000 7,359E-04 0,03835208 ! regulation of T cell differentiation GO:0045580 43 31 1,000 8,414E-04 0,04323288 ! pyridine nucleotide metabolic process GO:0019362 35 31 1,000 8,414E-04 0,04263242 ! response to calcium ion GO:0051592 34 31 1,000 8,414E-04 0,04204841 ! drug binding GO:0008144 34 31 1,000 8,414E-04 0,04148019 ! positive regulation of T cell proliferation GO:0042102 38 31 1,000 8,414E-04 0,04092712 ! positive regulation of mast cell proliferation GO:0070668 43 36 1,000 1,135E-03 0,05448706 GO:0050671|positive regulation of lymphocyte proliferation, ! positive regulation of leukocyte proliferation GO:0070665 47 37 1,000 1,199E-03 0,05680406 GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of lymphocyte differentiation GO:0045619 51 38 1,000 1,265E-03 0,05914065 ! ribonucleoside metabolic process GO:0009119 47 40 1,000 1,401E-03 0,06467731 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 1,000 1,401E-03 0,06386885 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 1,000 1,471E-03 0,06625869 ! cellular amide metabolic process GO:0043603 56 42 1,000 1,543E-03 0,0686646 ! positive regulation of cell cycle GO:0045787 56 43 1,000 1,617E-03 0,0710858 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 1,000 1,617E-03 0,07023954 ! negative regulation of cell migration GO:0030336 53 44 1,000 1,693E-03 0,0726566 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 1,000 1,77E-03 0,07508778 ! regulation of T cell proliferation GO:0042129 53 45 1,000 1,77E-03 0,0742247 ! response to UV GO:0009411 59 45 1,000 1,77E-03 0,07338124 ! mRNA binding GO:0003729 65 47 1,000 1,93E-03 0,0790911 ! negative regulation of cell motion GO:0051271 60 49 1,000 2,096E-03 0,08494078 ! regulation of mast cell proliferation GO:0070666 57 49 1,000 2,096E-03 0,08400736 ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 1,000 2,268E-03 0,08993597 ! regulation of lymphocyte proliferation GO:0050670 61 52 1,000 2,357E-03 0,09244884 ! basement membrane GO:0005604 55 53 1,000 2,447E-03 0,09497124 ! water-soluble vitamin metabolic process GO:0006767 59 53 1,000 2,447E-03 0,09397154 ! heterocycle catabolic process GO:0046700 56 53 1,000 2,447E-03 0,09299267 ! regulation of leukocyte proliferation GO:0070663 65 53 1,000 2,447E-03 0,09203399 GO:0032944|regulation of mononuclear cell proliferation, ! nucleoside metabolic process GO:0009116 62 54 1,000 2,539E-03 0,09451793 ! coenzyme biosynthetic process GO:0009108 68 55 1,000 2,633E-03 0,09701119 ! extracellular matrix organization GO:0030198 77 55 1,000 2,633E-03 0,09604108 ! positive regulation of T cell activation GO:0050870 74 56 1,000 2,728E-03 0,09852804 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 1,000 3,023E-03 0,10811858 ! copper ion binding GO:0005507 85 60 1,000 3,125E-03 0,11066661 ! response to metal ion GO:0010038 65 60 1,000 3,125E-03 0,1096025 ! secondary metabolic process GO:0019748 67 60 1,000 3,125E-03 0,10855867 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 1,000 3,228E-03 0,11108511 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 1,000 3,333E-03 0,11361835 ! response to unfolded protein GO:0006986 66 64 1,000 3,547E-03 0,11980302 ! positive regulation of lymphocyte activation GO:0051251 83 65 1,000 3,656E-03 0,12236804 ! response to inorganic substance GO:0010035 71 65 1,000 3,656E-03 0,1212556 ! protein kinase regulator activity GO:0019887 74 66 1,000 3,767E-03 0,12381284 ! positive regulation of phosphorylation GO:0042327 82 70 1,000 4,227E-03 0,13768339 ! response to protein stimulus GO:0051789 73 70 1,000 4,227E-03 0,13646495 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 1,000 4,466E-03 0,14292201 GO:0045937|positive regulation of phosphate metabolic process, ! response to drug GO:0042493 94 73 1,000 4,588E-03 0,14554625 ! positive regulation of leukocyte activation GO:0002696 92 73 1,000 4,588E-03 0,14429154 ! positive regulation of cell activation GO:0050867 94 75 1,000 4,837E-03 0,15080351 ! transcription initiation GO:0006352 84 75 1,000 4,837E-03 0,14952552 ! kinase regulator activity GO:0019207 93 76 1,000 4,963E-03 0,15214676 ! cofactor biosynthetic process GO:0051188 93 78 1,000 5,221E-03 0,15870839 ! positive regulation of protein modification process GO:0031401 100 78 1,000 5,221E-03 0,15739675 ! vitamin metabolic process GO:0006766 86 79 1,000 5,352E-03 0,16002513 ! ossification GO:0001503 111 82 1,000 5,754E-03 0,17065219 ! forebrain development GO:0030900 93 82 1,000 5,754E-03 0,16927596 ! heparin binding GO:0008201 108 82 1,000 5,754E-03 0,16792175 ! regulation of T cell activation GO:0050863 104 83 1,000 5,891E-03 0,17055723 ! bone development GO:0060348 112 83 1,000 5,891E-03 0,16921426 ! nitrogen compound catabolic process GO:0044270 91 84 1,000 6,03E-03 0,17184101 ! growth factor binding GO:0019838 102 88 1,000 6,599E-03 0,18660124 ! protein kinase binding GO:0019901 115 89 1,000 6,745E-03 0,18926157 ! anion binding GO:0043168 104 90 1,000 6,892E-03 0,19192218 ! extracellular matrix part GO:0044420 111 90 1,000 6,892E-03 0,19046822 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 6,926E-03 0,18996806 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 6,926E-03 0,18855039 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 6,926E-03 0,18715372 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 6,926E-03 0,18577759 ! response to superoxide GO:0000303 5 5 0,000 6,926E-03 0,18442155 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 6,926E-03 0,18308516 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 6,926E-03 0,181768 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 6,926E-03 0,18046966 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 6,926E-03 0,17918973 ! quinolinate metabolic process GO:0046874 5 5 0,000 6,926E-03 0,17792784 ! biotin binding GO:0009374 7 5 0,000 6,926E-03 0,17668358 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 6,926E-03 0,17545662 ! tongue development GO:0043586 6 5 0,000 6,926E-03 0,17424657 ! nose development GO:0043584 5 5 0,000 6,926E-03 0,1730531 ! cell proliferation in forebrain GO:0021846 5 5 0,000 6,926E-03 0,17187587 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 6,926E-03 0,17071454 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 6,926E-03 0,16956881 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 6,926E-03 0,16843835 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 6,926E-03 0,16732286 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 6,926E-03 0,16622206 ! glycolipid transport GO:0046836 6 5 0,000 6,926E-03 0,16513564 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 6,926E-03 0,16406333 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 6,926E-03 0,16300486 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 6,926E-03 0,16195995 ! neuron adhesion GO:0007158 5 5 0,000 6,926E-03 0,16092836 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 6,926E-03 0,15990983 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 6,926E-03 0,1589041 ! opioid peptide activity GO:0001515 6 5 0,000 6,926E-03 0,15791095 ! selenocysteine incorporation GO:0001514 5 5 0,000 6,926E-03 0,15693014 GO:0006451|translational readthrough, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 6,926E-03 0,15596144 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 6,926E-03 0,15500462 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 6,926E-03 0,15405947 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 6,926E-03 0,15312577 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,926E-03 0,15220333 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 6,926E-03 0,15129193 ! clathrin coat assembly GO:0048268 6 5 0,000 6,926E-03 0,15039138 ! cerebral cortex cell migration GO:0021795 5 5 0,000 6,926E-03 0,14950149 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 6,926E-03 0,14862207 ! membrane hyperpolarization GO:0060081 5 5 0,000 6,926E-03 0,14775294 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 6,926E-03 0,14689391 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 6,926E-03 0,14604481 ! translation repressor activity GO:0030371 8 5 0,000 6,926E-03 0,14520547 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 6,926E-03 0,14437573 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 6,926E-03 0,14355541 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 6,926E-03 0,14274437 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 6,926E-03 0,14194243 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 6,926E-03 0,14114946 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 6,926E-03 0,14036529 ! negative regulation of heart contraction GO:0045822 5 5 0,000 6,926E-03 0,13958979 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 6,926E-03 0,13882282 ! microfibril GO:0001527 5 5 0,000 6,926E-03 0,13806422 ! troponin I binding GO:0031013 5 5 0,000 6,926E-03 0,13731387 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 6,926E-03 0,13657164 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 6,926E-03 0,13583738 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 6,926E-03 0,13511098 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 6,926E-03 0,1343923 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 6,926E-03 0,13368123 ! protein lipoylation GO:0009249 14 5 0,000 6,926E-03 0,13297765 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,926E-03 0,13228143 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 6,926E-03 0,13159246 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 6,926E-03 0,13091064 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 6,926E-03 0,13023584 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 6,926E-03 0,12956796 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 6,926E-03 0,1289069 ! glutamate catabolic process GO:0006538 6 5 0,000 6,926E-03 0,12825255 ! microvillus organization GO:0032528 5 5 0,000 6,926E-03 0,12760481 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 6,926E-03 0,12696358 ! tyrosine catabolic process GO:0006572 5 5 0,000 6,926E-03 0,12632876 ! response to pH GO:0009268 5 5 0,000 6,926E-03 0,12570026 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 6,926E-03 0,12507798 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 6,926E-03 0,12446184 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 6,926E-03 0,12385173 ! polyol biosynthetic process GO:0046173 5 5 0,000 6,926E-03 0,12324757 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 6,926E-03 0,12264928 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,926E-03 0,12205678 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 6,926E-03 0,12146996 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 6,926E-03 0,12088877 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 6,926E-03 0,12031311 ! anaerobic glycolysis GO:0019642 5 5 0,000 6,926E-03 0,1197429 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 6,926E-03 0,11917808 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 6,926E-03 0,11861856 ! peroxisomal matrix GO:0005782 5 5 0,000 6,926E-03 0,11806426 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 6,926E-03 0,11751513 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 6,926E-03 0,11697108 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 6,926E-03 0,11643204 ! multivesicular body GO:0005771 5 5 0,000 6,926E-03 0,11589795 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 6,926E-03 0,11536873 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 6,926E-03 0,11484433 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 6,926E-03 0,11432467 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 6,926E-03 0,1138097 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 6,926E-03 0,11329934 ! epithelial cell maturation GO:0002070 14 5 0,000 6,926E-03 0,11279354 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 6,926E-03 0,11229223 ! muscle thin filament assembly GO:0030240 5 5 0,000 6,926E-03 0,11179537 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 6,926E-03 0,11130287 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 6,926E-03 0,1108147 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 0,000 6,926E-03 0,1103308 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 6,926E-03 0,1098511 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,926E-03 0,10937555 ! positive regulation of translational initiation GO:0045948 6 5 0,000 6,926E-03 0,10890411 ! nonhomologous end joining complex GO:0070419 6 5 0,000 6,926E-03 0,10843671 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 6,926E-03 0,1079733 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 6,926E-03 0,10751384 ! ATPase activator activity GO:0001671 5 5 0,000 6,926E-03 0,10705827 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 6,926E-03 0,10660655 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 0,000 6,926E-03 0,10615862 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 6,926E-03 0,10571445 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 6,926E-03 0,10527397 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 6,926E-03 0,10483715 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 6,926E-03 0,10440394 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 6,926E-03 0,10397429 ! cardiac myofibril assembly GO:0055003 5 5 0,000 6,926E-03 0,10354817 ! anterograde axon cargo transport GO:0008089 6 5 0,000 6,926E-03 0,10312552 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,926E-03 0,10270631 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 6,926E-03 0,1022905 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 6,926E-03 0,10187803 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 6,926E-03 0,10146889 ! protein localization to telomere GO:0070198 7 5 0,000 6,926E-03 0,10106301 ! response to exogenous dsRNA GO:0043330 5 5 0,000 6,926E-03 0,10066037 ! MutSalpha complex binding GO:0032407 7 5 0,000 6,926E-03 0,10026092 ! bile acid biosynthetic process GO:0006699 5 5 0,000 6,926E-03 0,09986463 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 6,926E-03 0,09947147 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 6,926E-03 0,09908138 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,926E-03 0,09869435 ! nerve growth factor binding GO:0048406 7 5 0,000 6,926E-03 0,09831032 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 6,926E-03 0,09792927 ! high-density lipoprotein binding GO:0008035 6 5 0,000 6,926E-03 0,09755117 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 6,926E-03 0,09717597 ! transcription initiation factor activity GO:0016986 5 5 0,000 6,926E-03 0,09680365 ! gas homeostasis GO:0033483 5 5 0,000 6,926E-03 0,09643417 ! Schwann cell development GO:0014044 5 5 0,000 6,926E-03 0,0960675 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 6,926E-03 0,09570361 ! cyclohydrolase activity GO:0019238 5 5 0,000 6,926E-03 0,09534246 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 6,926E-03 0,09498403 ! response to pheromone GO:0019236 5 5 0,000 6,926E-03 0,09462829 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 6,926E-03 0,0942752 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 6,926E-03 0,09392473 ! rhombomere development GO:0021546 6 5 0,000 6,926E-03 0,09357686 ! alanine transport GO:0032328 6 5 0,000 6,926E-03 0,09323156 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 6,926E-03 0,0928888 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 6,926E-03 0,09254854 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 6,926E-03 0,09221078 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 6,926E-03 0,09187546 ! regulation of meiosis GO:0040020 6 5 0,000 6,926E-03 0,09154258 GO:0051445|regulation of meiotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 6,926E-03 0,0912121 ! lymphocyte costimulation GO:0031294 5 5 0,000 6,926E-03 0,090884 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 6,926E-03 0,09055825 ! RS domain binding GO:0050733 6 5 0,000 6,926E-03 0,09023483 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 6,926E-03 0,08991371 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 6,926E-03 0,08959487 ! B cell homeostasis GO:0001782 6 5 0,000 6,926E-03 0,08927828 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 6,926E-03 0,08896392 ! anaphase GO:0051322 7 5 0,000 6,926E-03 0,08865176 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 6,926E-03 0,08834179 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 6,926E-03 0,08803398 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 6,926E-03 0,08772831 ! AP-2 adaptor complex GO:0030122 5 5 0,000 6,926E-03 0,08742475 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 6,926E-03 0,08712328 ! diuresis GO:0030146 5 5 0,000 6,926E-03 0,08682389 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 6,926E-03 0,08652655 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 6,926E-03 0,08623124 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 6,926E-03 0,08593793 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 6,926E-03 0,08564662 ! GTP-Rho binding GO:0017049 5 5 0,000 6,926E-03 0,08535727 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 6,926E-03 0,08506987 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,926E-03 0,0847844 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 6,926E-03 0,08450084 ! brown fat cell differentiation GO:0050873 5 5 0,000 6,926E-03 0,08421918 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,926E-03 0,08393938 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 6,926E-03 0,08366143 ! TAP complex GO:0042825 5 5 0,000 6,926E-03 0,08338532 ! platelet dense granule GO:0042827 6 5 0,000 6,926E-03 0,08311103 ! bHLH transcription factor binding GO:0043425 5 5 0,000 6,926E-03 0,08283853 ! secretory granule organization GO:0033363 5 5 0,000 6,926E-03 0,08256782 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 6,926E-03 0,08229887 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 6,926E-03 0,08203166 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 6,926E-03 0,08176619 ! lamin binding GO:0005521 8 5 0,000 6,926E-03 0,08150243 ! aldehyde-lyase activity GO:0016832 6 5 0,000 6,926E-03 0,08124036 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,926E-03 0,08097998 ! neural plate morphogenesis GO:0001839 6 5 0,000 6,926E-03 0,08072125 ! cyclosporin A binding GO:0016018 6 5 0,000 6,926E-03 0,08046418 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 6,926E-03 0,08020874 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 6,926E-03 0,07995491 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 6,926E-03 0,07970269 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 6,926E-03 0,07945205 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 6,926E-03 0,07920299 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 6,926E-03 0,07895548 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 6,926E-03 0,07870951 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 6,926E-03 0,07846507 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 6,926E-03 0,07822214 ! organ or tissue specific immune response GO:0002251 6 5 0,000 6,926E-03 0,07798072 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 6,926E-03 0,07774078 ! retina homeostasis GO:0001895 5 5 0,000 6,926E-03 0,07750231 ! prepulse inhibition GO:0060134 8 5 0,000 6,926E-03 0,0772653 ! maternal placenta development GO:0001893 5 5 0,000 6,926E-03 0,07702973 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 6,926E-03 0,0767956 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 6,926E-03 0,07656289 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 6,926E-03 0,07633158 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 6,926E-03 0,07610166 ! protein palmitoylation GO:0018345 5 5 0,000 6,926E-03 0,07587313 ! protein amino acid prenylation GO:0018346 6 5 0,000 6,926E-03 0,07564597 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 6,926E-03 0,07542016 ! stem cell division GO:0017145 6 5 0,000 6,926E-03 0,07519569 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 6,926E-03 0,07497256 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 6,926E-03 0,07475075 ! organ regeneration GO:0031100 6 5 0,000 6,926E-03 0,07453024 ! lymphocyte apoptosis GO:0070227 6 5 0,000 6,926E-03 0,07431104 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 6,926E-03 0,07409312 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 6,926E-03 0,07387647 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 6,926E-03 0,07366109 ! acyl carrier activity GO:0000036 5 5 0,000 6,926E-03 0,07344696 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 6,926E-03 0,07323407 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 6,926E-03 0,07302241 ! phagocytic vesicle GO:0045335 5 5 0,000 6,926E-03 0,07281197 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 6,926E-03 0,07260274 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 6,926E-03 0,07239471 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 6,926E-03 0,07218786 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 6,926E-03 0,0719822 ! polyol transport GO:0015791 8 5 0,000 6,926E-03 0,07177771 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 6,926E-03 0,07157437 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 6,926E-03 0,07137218 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 6,926E-03 0,07117113 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 6,926E-03 0,07097122 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 6,926E-03 0,07077242 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 6,926E-03 0,07057473 ! ethanol metabolic process GO:0006067 6 5 0,000 6,926E-03 0,07037814 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 6,926E-03 0,07018265 ! cobalt ion transport GO:0006824 5 5 0,000 6,926E-03 0,06998823 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 6,926E-03 0,0697949 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 6,926E-03 0,06960262 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 6,926E-03 0,06941141 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 6,926E-03 0,06922124 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 6,926E-03 0,06903211 ! sterol carrier activity GO:0005498 6 5 0,000 6,926E-03 0,06884401 ! adaptation of signaling pathway GO:0022401 6 5 0,000 6,926E-03 0,06865694 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 6,926E-03 0,06847087 ! response to acid GO:0001101 7 5 0,000 6,926E-03 0,06828582 ! fibril organization GO:0043206 5 5 0,000 6,926E-03 0,06810176 ! malate metabolic process GO:0006108 6 5 0,000 6,926E-03 0,06791869 ! regulation of dopamine uptake GO:0051584 7 5 0,000 6,926E-03 0,0677366 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 6,926E-03 0,06755549 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 6,926E-03 0,06737534 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 6,926E-03 0,06719615 ! protein maturation by protein folding GO:0022417 5 5 0,000 6,926E-03 0,06701791 ! activation of protein kinase B activity GO:0032148 15 5 0,000 6,926E-03 0,06684062 ! origin recognition complex GO:0000808 5 5 0,000 6,926E-03 0,06666425 ! neurexin binding GO:0042043 6 5 0,000 6,926E-03 0,06648882 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 6,926E-03 0,06631431 ! protein amino acid dealkylation GO:0008214 5 5 0,000 6,926E-03 0,06614071 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 6,926E-03 0,06596802 ! lipoic acid binding GO:0031405 5 5 0,000 6,926E-03 0,06579623 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 6,926E-03 0,06562533 ! lithium ion binding GO:0031403 6 5 0,000 6,926E-03 0,06545532 ! grooming behavior GO:0007625 7 5 0,000 6,926E-03 0,06528618 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 6,926E-03 0,06511792 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 6,926E-03 0,06495052 ! lymph vessel development GO:0001945 6 5 0,000 6,926E-03 0,06478398 ! bicarbonate transport GO:0015701 5 5 0,000 6,926E-03 0,06461829 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 0,000 6,926E-03 0,06445345 GO:0010811|positive regulation of cell-substrate adhesion, ! response to interferon-gamma GO:0034341 6 5 0,000 6,926E-03 0,06428945 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 6,926E-03 0,06412628 ! endothelial cell proliferation GO:0001935 8 5 0,000 6,926E-03 0,06396393 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 6,926E-03 0,06380241 ! dorsal spinal cord development GO:0021516 6 5 0,000 6,926E-03 0,06364169 ! activation of MAPKKK activity GO:0000185 5 5 0,000 6,926E-03 0,06348179 ! synaptic vesicle maturation GO:0016188 6 5 0,000 6,926E-03 0,06332269 ! sphingoid catabolic process GO:0046521 5 5 0,000 6,926E-03 0,06316438 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 6,926E-03 0,06300686 ! neutrophil mediated immunity GO:0002446 5 5 0,000 6,926E-03 0,06285013 ! intercellular canaliculus GO:0046581 5 5 0,000 6,926E-03 0,06269418 ! dopamine binding GO:0035240 7 5 0,000 6,926E-03 0,06253899 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 6,926E-03 0,06238457 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 6,926E-03 0,06223092 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 6,926E-03 0,06207802 ! amine oxidase activity GO:0008131 7 5 0,000 6,926E-03 0,06192586 ! monocyte activation GO:0042117 9 5 0,000 6,926E-03 0,06177446 ! negative regulation of protein binding GO:0032091 5 5 0,000 6,926E-03 0,06162379 ! regulation of response to food GO:0032095 5 5 0,000 6,926E-03 0,06147385 ! response to food GO:0032094 6 5 0,000 6,926E-03 0,06132464 ! positive regulation of protein binding GO:0032092 5 5 0,000 6,926E-03 0,06117616 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 6,926E-03 0,06102839 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 6,926E-03 0,06088133 ! hedgehog receptor activity GO:0008158 5 5 0,000 6,926E-03 0,06073498 ! lipoprotein catabolic process GO:0042159 5 5 0,000 6,926E-03 0,06058933 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 6,926E-03 0,06044438 ! purine salvage GO:0043101 7 5 0,000 6,926E-03 0,06030013 ! small-subunit processome GO:0032040 5 5 0,000 6,926E-03 0,06015655 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 6,926E-03 0,06001366 ! ciliary rootlet GO:0035253 5 5 0,000 6,926E-03 0,05987145 ! myosin heavy chain binding GO:0032036 5 5 0,000 6,926E-03 0,05972991 ! nucleobase transport GO:0015851 5 5 0,000 6,926E-03 0,05958904 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 6,926E-03 0,05944883 ! GPI anchor binding GO:0034235 6 5 0,000 6,926E-03 0,05930928 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,926E-03 0,05917038 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 6,926E-03 0,05903213 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 6,926E-03 0,05889453 ! basic amino acid transport GO:0015802 5 5 0,000 6,926E-03 0,05875756 ! dendritic shaft GO:0043198 5 5 0,000 6,926E-03 0,05862124 ! terminal button GO:0043195 7 5 0,000 6,926E-03 0,05848554 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 6,926E-03 0,05835047 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 6,926E-03 0,05821602 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 6,926E-03 0,05808219 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 6,926E-03 0,05794897 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 6,926E-03 0,05781637 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 6,926E-03 0,05768437 ! response to UV-C GO:0010225 15 5 0,000 6,926E-03 0,05755297 ! positive regulation of organ growth GO:0046622 5 5 0,000 6,926E-03 0,05742217 ! response to arsenic GO:0046685 6 5 0,000 6,926E-03 0,05729196 ! IgE binding GO:0019863 5 5 0,000 6,926E-03 0,05716234 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 6,926E-03 0,0570333 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 6,926E-03 0,05690485 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 6,926E-03 0,05677697 ! response to copper ion GO:0046688 5 5 0,000 6,926E-03 0,05664967 ! response to cadmium ion GO:0046686 5 5 0,000 6,926E-03 0,05652294 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 6,926E-03 0,05639677 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 6,926E-03 0,05627116 ! protein autoprocessing GO:0016540 6 5 0,000 6,926E-03 0,05614612 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 6,926E-03 0,05602162 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 6,926E-03 0,05589768 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 6,926E-03 0,05577429 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 6,926E-03 0,05565144 ! mitotic recombination GO:0006312 15 5 0,000 6,926E-03 0,05552913 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 6,926E-03 0,05540735 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 6,926E-03 0,05528611 ! membrane to membrane docking GO:0022614 5 5 0,000 6,926E-03 0,0551654 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 6,926E-03 0,05504521 ! translation activator activity GO:0008494 5 5 0,000 6,926E-03 0,05492555 ! somatostatin receptor activity GO:0004994 5 5 0,000 6,926E-03 0,0548064 ! melanocortin receptor activity GO:0004977 6 5 0,000 6,926E-03 0,05468778 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 6,926E-03 0,05456966 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 6,926E-03 0,05445205 ! salivary gland morphogenesis GO:0007435 5 5 0,000 6,926E-03 0,05433495 ! galactosidase activity GO:0015925 5 5 0,000 6,926E-03 0,05421835 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 6,926E-03 0,05410225 ! cellular response to nutrient GO:0031670 5 5 0,000 6,926E-03 0,05398665 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 6,926E-03 0,05387154 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 6,926E-03 0,05375692 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 6,926E-03 0,05364279 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 6,926E-03 0,05352914 ! A band GO:0031672 5 5 0,000 6,926E-03 0,05341597 ! heat generation GO:0031649 5 5 0,000 6,926E-03 0,05330328 ! flagellum organization GO:0043064 5 5 0,000 6,926E-03 0,05319106 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 6,926E-03 0,05307931 ! disaccharide metabolic process GO:0005984 6 5 0,000 6,926E-03 0,05296803 ! glycogen catabolic process GO:0005980 16 5 0,000 6,926E-03 0,05285722 ! dopamine biosynthetic process GO:0042416 6 5 0,000 6,926E-03 0,05274687 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 6,926E-03 0,05263698 ! chromocenter GO:0010369 5 5 0,000 6,926E-03 0,05252755 ! glial cell migration GO:0008347 5 5 0,000 6,926E-03 0,05241857 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 6,926E-03 0,05231005 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 6,926E-03 0,05220197 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 6,926E-03 0,05209434 ! growth hormone receptor binding GO:0005131 5 5 0,000 6,926E-03 0,05198715 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 6,926E-03 0,0518804 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 6,926E-03 0,05177408 ! aminomethyltransferase activity GO:0004047 5 5 0,000 6,926E-03 0,05166821 ! aminoacylase activity GO:0004046 5 5 0,000 6,926E-03 0,05156276 ! penetration of zona pellucida GO:0007341 6 5 0,000 6,926E-03 0,05145774 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 6,926E-03 0,05135316 ! nucleus localization GO:0051647 5 5 0,000 6,926E-03 0,05124899 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 6,926E-03 0,05114525 ! carnitine metabolic process GO:0009437 5 5 0,000 6,926E-03 0,05104192 GO:0006577|betaine metabolic process, ! spindle GO:0005819 126 92 1,000 7,191E-03 0,05288996 ! extracellular structure organization GO:0043062 119 92 1,000 7,191E-03 0,05278354 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 8,306E-03 0,06084071 ! regulation of helicase activity GO:0051095 6 6 0,000 8,306E-03 0,06071878 ! response to oxygen radical GO:0000305 6 6 0,000 8,306E-03 0,06059734 ! positive regulation of axon extension GO:0045773 7 6 0,000 8,306E-03 0,06047639 ! forebrain neuron differentiation GO:0021879 6 6 0,000 8,306E-03 0,06035592 ! forebrain regionalization GO:0021871 7 6 0,000 8,306E-03 0,06023593 ! meiotic prophase I GO:0007128 7 6 0,000 8,306E-03 0,06011641 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 8,306E-03 0,05999737 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 8,306E-03 0,0598788 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 8,306E-03 0,05976069 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 8,306E-03 0,05964306 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 8,306E-03 0,05952588 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 8,306E-03 0,05940916 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 8,306E-03 0,0592929 ! protein amino acid sulfation GO:0006477 9 6 0,000 8,306E-03 0,05917709 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 8,306E-03 0,05906174 ! establishment of tissue polarity GO:0007164 8 6 0,000 8,306E-03 0,05894683 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 8,306E-03 0,05883237 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 8,306E-03 0,05871836 ! embryonic camera-type eye development GO:0031076 9 6 0,000 8,306E-03 0,05860478 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 8,306E-03 0,05849165 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 8,306E-03 0,05837894 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 8,306E-03 0,05826668 ! Notch receptor processing GO:0007220 7 6 0,000 8,306E-03 0,05815484 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 8,306E-03 0,05804343 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 8,306E-03 0,05793245 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 8,306E-03 0,05782189 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 8,306E-03 0,05771176 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 8,306E-03 0,05760204 ! neurofilament GO:0005883 7 6 0,000 8,306E-03 0,05749274 ! glial cell fate commitment GO:0021781 7 6 0,000 8,306E-03 0,05738385 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 8,306E-03 0,05727537 ! dynactin complex GO:0005869 7 6 0,000 8,306E-03 0,05716731 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 8,306E-03 0,05705965 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 8,306E-03 0,05695239 ! oocyte maturation GO:0001556 6 6 0,000 8,306E-03 0,05684554 ! DNA replication origin binding GO:0003688 6 6 0,000 8,306E-03 0,05673909 ! reflex GO:0060004 10 6 0,000 8,306E-03 0,05663303 ! positive regulation of glycolysis GO:0045821 6 6 0,000 8,306E-03 0,05652737 ! parathyroid gland development GO:0060017 6 6 0,000 8,306E-03 0,05642211 ! anagen GO:0042640 7 6 0,000 8,306E-03 0,05631723 ! protein-cofactor linkage GO:0018065 15 6 0,000 8,306E-03 0,05621275 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 8,306E-03 0,05610865 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 8,306E-03 0,05600494 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 8,306E-03 0,05590161 ! skeletal myofibril assembly GO:0014866 6 6 0,000 8,306E-03 0,05579866 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 8,306E-03 0,05569609 ! cysteine metabolic process GO:0006534 7 6 0,000 8,306E-03 0,05559389 ! glycine catabolic process GO:0006546 6 6 0,000 8,306E-03 0,05549207 ! adenohypophysis development GO:0021984 6 6 0,000 8,306E-03 0,05539063 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 8,306E-03 0,05528955 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 8,306E-03 0,05518884 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 8,306E-03 0,05508849 ! microtubule nucleation GO:0007020 7 6 0,000 8,306E-03 0,05498852 ! proline biosynthetic process GO:0006561 8 6 0,000 8,306E-03 0,0548889 ! tryptophan metabolic process GO:0006568 6 6 0,000 8,306E-03 0,05478964 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 8,306E-03 0,05469074 ! thyroid hormone generation GO:0006590 6 6 0,000 8,306E-03 0,0545922 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 8,306E-03 0,05449401 ! retinoid X receptor binding GO:0046965 7 6 0,000 8,306E-03 0,05439618 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 8,306E-03 0,0542987 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 8,306E-03 0,05420156 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 8,306E-03 0,05410477 ! sister chromatid cohesion GO:0007062 6 6 0,000 8,306E-03 0,05400833 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 8,306E-03 0,05391223 ! positive regulation of transporter activity GO:0032411 8 6 0,000 8,306E-03 0,05381647 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 8,306E-03 0,05372105 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 8,306E-03 0,05362597 ! p53 binding GO:0002039 6 6 0,000 8,306E-03 0,05353122 ! demethylase activity GO:0032451 6 6 0,000 8,306E-03 0,05343681 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 8,306E-03 0,05334273 ! regulation of platelet activation GO:0010543 7 6 0,000 8,306E-03 0,05324898 ! lipid phosphatase activity GO:0042577 7 6 0,000 8,306E-03 0,05315557 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 8,306E-03 0,05306247 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 8,306E-03 0,05296971 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 8,306E-03 0,05287726 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 8,306E-03 0,05278514 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 8,306E-03 0,05269334 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 8,306E-03 0,05260186 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 8,306E-03 0,0525107 ! LIM domain binding GO:0030274 7 6 0,000 8,306E-03 0,05241985 ! negative regulation of translational initiation GO:0045947 6 6 0,000 8,306E-03 0,05232931 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 8,306E-03 0,05223909 ! 5S class rRNA transcription GO:0042791 6 6 0,000 8,306E-03 0,05214918 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 8,306E-03 0,05205957 ! axon guidance receptor activity GO:0008046 6 6 0,000 8,306E-03 0,05197028 ! zinc ion homeostasis GO:0055069 7 6 0,000 8,306E-03 0,05188129 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 8,306E-03 0,0517926 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 8,306E-03 0,05170422 ! protein targeting to lysosome GO:0006622 6 6 0,000 8,306E-03 0,05161614 ! hyaluronan metabolic process GO:0030212 8 6 0,000 8,306E-03 0,05152835 ! protein retention in ER lumen GO:0006621 6 6 0,000 8,306E-03 0,05144087 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 8,306E-03 0,05135368 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 8,306E-03 0,05126679 ! dynein binding GO:0045502 6 6 0,000 8,306E-03 0,05118019 ! regulation of dendrite development GO:0050773 6 6 0,000 8,306E-03 0,05109388 ! peptidyl-arginine modification GO:0018195 6 6 0,000 8,306E-03 0,05100787 ! eating behavior GO:0042755 7 6 0,000 8,306E-03 0,05092214 ! protein localization to chromosome GO:0034502 8 6 0,000 8,306E-03 0,0508367 ! Hsp90 protein binding GO:0051879 7 6 0,000 8,306E-03 0,05075154 ! glycolipid binding GO:0051861 7 6 0,000 8,306E-03 0,05066668 ! MutLalpha complex binding GO:0032405 8 6 0,000 8,306E-03 0,05058209 ! mast cell activation GO:0045576 6 6 0,000 8,306E-03 0,05049779 ! regulation of focal adhesion formation GO:0051893 6 6 0,000 8,306E-03 0,05041376 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 8,306E-03 0,05033002 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 8,306E-03 0,05024655 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 8,306E-03 0,05016336 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 8,306E-03 0,05008045 ! lipoxygenase activity GO:0016165 6 6 0,000 8,306E-03 0,04999781 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 8,306E-03 0,04991544 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 8,306E-03 0,04983334 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 8,306E-03 0,04975151 ! DNA replication factor C complex GO:0005663 7 6 0,000 8,306E-03 0,04966995 ! DNA replication factor A complex GO:0005662 7 6 0,000 8,306E-03 0,04958866 ! establishment of chromosome localization GO:0051303 15 6 0,000 8,306E-03 0,04950763 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 8,306E-03 0,04942687 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 8,306E-03 0,04934637 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 8,306E-03 0,04926613 ! chromatin assembly complex GO:0005678 16 6 0,000 8,306E-03 0,04918616 ! sex chromatin GO:0001739 6 6 0,000 8,306E-03 0,04910644 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 8,306E-03 0,04902698 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 8,306E-03 0,04894777 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 8,306E-03 0,04886883 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 8,306E-03 0,04879013 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 8,306E-03 0,04871169 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 8,306E-03 0,0486335 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 8,306E-03 0,04855556 ! phosphatidylserine binding GO:0001786 6 6 0,000 8,306E-03 0,04847788 ! alpha-mannosidase activity GO:0004559 8 6 0,000 8,306E-03 0,04840043 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 8,306E-03 0,04832324 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 8,306E-03 0,04824629 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 8,306E-03 0,04816959 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 8,306E-03 0,04809313 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 8,306E-03 0,04801691 ! leading edge membrane GO:0031256 8 6 0,000 8,306E-03 0,04794094 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 8,306E-03 0,0478652 ! CARD domain binding GO:0050700 6 6 0,000 8,306E-03 0,0477897 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 8,306E-03 0,04771444 ! COPII vesicle coat GO:0030127 7 6 0,000 8,306E-03 0,04763942 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 8,306E-03 0,04756463 ! glutathione biosynthetic process GO:0006750 7 6 0,000 8,306E-03 0,04749008 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 8,306E-03 0,04741576 ! positive regulation of epidermis development GO:0045684 8 6 0,000 8,306E-03 0,04734168 ! proteasome regulator activity GO:0010860 6 6 0,000 8,306E-03 0,04726782 ! ceramidase activity GO:0017040 6 6 0,000 8,306E-03 0,04719419 ! antibiotic transport GO:0042891 7 6 0,000 8,306E-03 0,0471208 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 8,306E-03 0,04704763 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 8,306E-03 0,04697469 ! sodium channel regulator activity GO:0017080 6 6 0,000 8,306E-03 0,04690197 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 8,306E-03 0,04682948 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 8,306E-03 0,04675721 ! response to fluid shear stress GO:0034405 6 6 0,000 8,306E-03 0,04668517 ! lymph node development GO:0048535 6 6 0,000 8,306E-03 0,04661334 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 8,306E-03 0,04654174 ! triglyceride catabolic process GO:0019433 15 6 0,000 8,306E-03 0,04647036 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 8,306E-03 0,04639919 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 8,306E-03 0,04632824 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 8,306E-03 0,04625751 ! negative regulation of lipase activity GO:0060192 6 6 0,000 8,306E-03 0,046187 ! activation of innate immune response GO:0002218 6 6 0,000 8,306E-03 0,0461167 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 8,306E-03 0,04604661 ! sarcoglycan complex GO:0016012 8 6 0,000 8,306E-03 0,04597674 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 8,306E-03 0,04590708 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 8,306E-03 0,04583763 ! neural plate development GO:0001840 7 6 0,000 8,306E-03 0,04576839 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 8,306E-03 0,04569935 ! catecholamine transport GO:0051937 6 6 0,000 8,306E-03 0,04563053 ! ether hydrolase activity GO:0016803 7 6 0,000 8,306E-03 0,04556191 ! FACIT collagen GO:0005593 6 6 0,000 8,306E-03 0,0454935 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 8,306E-03 0,0454253 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 8,306E-03 0,04535729 ! collagen type IV GO:0005587 6 6 0,000 8,306E-03 0,0452895 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 8,306E-03 0,0452219 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 8,306E-03 0,0451545 ! drug metabolic process GO:0017144 6 6 0,000 8,306E-03 0,04508731 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 8,306E-03 0,04502032 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 8,306E-03 0,04495352 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 8,306E-03 0,04488692 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 8,306E-03 0,04482052 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 8,306E-03 0,04475432 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 8,306E-03 0,04468831 ! cellular anion homeostasis GO:0030002 6 6 0,000 8,306E-03 0,04462249 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 8,306E-03 0,04455687 ! negative regulation of protein ubiquitination GO:0031397 7 6 0,000 8,306E-03 0,04449144 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 8,306E-03 0,04442621 ! behavioral response to cocaine GO:0048148 9 6 0,000 8,306E-03 0,04436116 ! translation initiation factor binding GO:0031369 6 6 0,000 8,306E-03 0,0442963 ! nucleotide-sugar transport GO:0015780 6 6 0,000 8,306E-03 0,04423164 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 8,306E-03 0,04416716 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 8,306E-03 0,04410287 ! quaternary ammonium group binding GO:0050997 7 6 0,000 8,306E-03 0,04403877 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 8,306E-03 0,04397485 ! reproductive behavior GO:0019098 8 6 0,000 8,306E-03 0,04391112 ! response to growth hormone stimulus GO:0060416 7 6 0,000 8,306E-03 0,04384757 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 8,306E-03 0,04378421 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 8,306E-03 0,04372103 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 8,306E-03 0,04365803 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 8,306E-03 0,04359521 ! induction of positive chemotaxis GO:0050930 7 6 0,000 8,306E-03 0,04353258 ! cohesin complex GO:0008278 6 6 0,000 8,306E-03 0,04347012 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 8,306E-03 0,04340784 ! citrate metabolic process GO:0006101 7 6 0,000 8,306E-03 0,04334574 ! myelin sheath GO:0043209 8 6 0,000 8,306E-03 0,04328382 ! phototransduction, visible light GO:0007603 6 6 0,000 8,306E-03 0,04322207 ! opsonization GO:0008228 7 6 0,000 8,306E-03 0,0431605 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 8,306E-03 0,04309911 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 8,306E-03 0,04303789 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 8,306E-03 0,04297684 ! regulation of potassium ion transport GO:0043266 8 6 0,000 8,306E-03 0,04291597 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 8,306E-03 0,04285526 ! chemoattractant activity GO:0042056 6 6 0,000 8,306E-03 0,04279473 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 8,306E-03 0,04273438 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 8,306E-03 0,04267419 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 8,306E-03 0,04261417 ! leukocyte degranulation GO:0043299 6 6 0,000 8,306E-03 0,04255431 ! bile acid and bile salt transport GO:0015721 7 6 0,000 8,306E-03 0,04249463 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 8,306E-03 0,04243512 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 8,306E-03 0,04237577 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 8,306E-03 0,04231658 ! DNA topoisomerase activity GO:0003916 6 6 0,000 8,306E-03 0,04225756 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 8,306E-03 0,04219871 ! ceramide biosynthetic process GO:0046513 6 6 0,000 8,306E-03 0,04214002 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 8,306E-03 0,04208149 ! activin receptor activity GO:0017002 7 6 0,000 8,306E-03 0,04202312 ! astrocyte differentiation GO:0048708 6 6 0,000 8,306E-03 0,04196492 ! syncytium formation GO:0006949 6 6 0,000 8,306E-03 0,04190688 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 8,306E-03 0,04184899 ! neutrophil activation GO:0042119 6 6 0,000 8,306E-03 0,04179127 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 8,306E-03 0,04173371 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 8,306E-03 0,0416763 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 8,306E-03 0,04161906 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 8,306E-03 0,04156196 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 8,306E-03 0,04150503 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 8,306E-03 0,04144825 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 8,306E-03 0,04139163 ! neuron apoptosis GO:0051402 7 6 0,000 8,306E-03 0,04133516 ! folic acid transport GO:0015884 8 6 0,000 8,306E-03 0,04127884 ! carnitine transport GO:0015879 6 6 0,000 8,306E-03 0,04122268 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 8,306E-03 0,04116667 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 8,306E-03 0,04111082 ! S-methyltransferase activity GO:0008172 6 6 0,000 8,306E-03 0,04105511 ! phospholipase D activity GO:0004630 6 6 0,000 8,306E-03 0,04099956 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 8,306E-03 0,04094415 ! intercalated disc GO:0014704 8 6 0,000 8,306E-03 0,0408889 ! G2/M transition checkpoint GO:0031576 24 6 0,000 8,306E-03 0,04083379 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 8,306E-03 0,04077883 ! IgG binding GO:0019864 6 6 0,000 8,306E-03 0,04072402 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 8,306E-03 0,04066936 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 8,306E-03 0,04061484 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 8,306E-03 0,04056047 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 8,306E-03 0,04050625 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 8,306E-03 0,04045217 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 8,306E-03 0,04039823 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 8,306E-03 0,04034444 ! dendrite morphogenesis GO:0048813 7 6 0,000 8,306E-03 0,04029079 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 8,306E-03 0,04023728 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 8,306E-03 0,04018392 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 8,306E-03 0,04013069 ! nucleosome disassembly GO:0006337 7 6 0,000 8,306E-03 0,04007761 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 8,306E-03 0,04002467 ! regulation of mast cell activation GO:0033003 6 6 0,000 8,306E-03 0,03997186 ! tetracycline transporter activity GO:0008493 7 6 0,000 8,306E-03 0,0399192 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 8,306E-03 0,03986667 ! receptor internalization GO:0031623 8 6 0,000 8,306E-03 0,03981429 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 8,306E-03 0,03976204 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 8,306E-03 0,03970992 ! histamine receptor activity GO:0004969 7 6 0,000 8,306E-03 0,03965795 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 8,306E-03 0,03960611 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 8,306E-03 0,0395544 ! protein deubiquitination GO:0016579 6 6 0,000 8,306E-03 0,03950283 ! axonal fasciculation GO:0007413 7 6 0,000 8,306E-03 0,0394514 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 8,306E-03 0,03940009 ! cytidine deaminase activity GO:0004126 6 6 0,000 8,306E-03 0,03934892 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 8,306E-03 0,03929789 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 8,306E-03 0,03924698 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 8,306E-03 0,03919621 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 8,306E-03 0,03914557 ! glycine binding GO:0016594 9 6 0,000 8,306E-03 0,03909506 ! apical protein localization GO:0045176 7 6 0,000 8,306E-03 0,03904468 ! ankyrin binding GO:0030506 6 6 0,000 8,306E-03 0,03899443 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 8,306E-03 0,03894431 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 8,306E-03 0,03889432 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 8,306E-03 0,03884445 ! progesterone metabolic process GO:0042448 6 6 0,000 8,306E-03 0,03879471 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 8,306E-03 0,03874511 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 8,306E-03 0,03869562 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 8,306E-03 0,03864627 ! ATP catabolic process GO:0006200 6 6 0,000 8,306E-03 0,03859703 ! CoA carboxylase activity GO:0016421 6 6 0,000 8,306E-03 0,03854793 ! determination of adult lifespan GO:0008340 6 6 0,000 8,306E-03 0,03849895 ! S-acyltransferase activity GO:0016417 6 6 0,000 8,306E-03 0,03845009 ! somatic stem cell maintenance GO:0035019 6 6 0,000 8,306E-03 0,03840136 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 8,306E-03 0,03835275 ! IkappaB kinase complex GO:0008385 7 6 0,000 8,306E-03 0,03830426 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 8,306E-03 0,0382559 ! store-operated calcium channel activity GO:0015279 6 6 0,000 8,306E-03 0,03820766 ! alkaline phosphatase activity GO:0004035 7 6 0,000 8,306E-03 0,03815954 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 8,306E-03 0,03811154 ! unconventional myosin complex GO:0016461 8 6 0,000 8,306E-03 0,03806366 ! regulation of lymphocyte activation GO:0051249 123 100 1,000 8,446E-03 0,03865899 ! response to light stimulus GO:0009416 131 100 1,000 8,446E-03 0,03861054 ! tRNA transcription GO:0009304 7 7 0,000 9,683E-03 0,04421135 ! respiratory burst GO:0045730 7 7 0,000 9,683E-03 0,04415609 ! telencephalon cell migration GO:0022029 8 7 0,000 9,683E-03 0,04410096 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 9,683E-03 0,04404597 ! cation:chloride symporter activity GO:0015377 8 7 0,000 9,683E-03 0,04399112 ! RNA cap binding GO:0000339 8 7 0,000 9,683E-03 0,0439364 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 9,683E-03 0,04388182 ! ephrin receptor binding GO:0046875 9 7 0,000 9,683E-03 0,04382738 ! male meiosis I GO:0007141 7 7 0,000 9,683E-03 0,04377307 ! synapsis GO:0007129 7 7 0,000 9,683E-03 0,0437189 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 9,683E-03 0,04366486 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 9,683E-03 0,04361095 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 9,683E-03 0,04355717 ! signal peptide processing GO:0006465 7 7 0,000 9,683E-03 0,04350353 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 9,683E-03 0,04345002 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 9,683E-03 0,04339664 ! macrophage chemotaxis GO:0048246 7 7 0,000 9,683E-03 0,0433434 ! Golgi cisterna membrane GO:0032580 7 7 0,000 9,683E-03 0,04329028 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 9,683E-03 0,04323729 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 9,683E-03 0,04318444 ! smoothened signaling pathway GO:0007224 8 7 0,000 9,683E-03 0,04313171 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 9,683E-03 0,04307911 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 9,683E-03 0,04302664 ! cytoplasmic microtubule GO:0005881 7 7 0,000 9,683E-03 0,04297429 ! Arp2/3 protein complex GO:0005885 8 7 0,000 9,683E-03 0,04292208 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 9,683E-03 0,04286999 ! ATPase binding GO:0051117 8 7 0,000 9,683E-03 0,04281802 ! positive regulation of isotype switching GO:0045830 7 7 0,000 9,683E-03 0,04276618 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 9,683E-03 0,04271447 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 9,683E-03 0,04266288 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 9,683E-03 0,04261142 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,683E-03 0,04256008 ! thymic T cell selection GO:0045061 16 7 0,000 9,683E-03 0,04250887 ! transepithelial chloride transport GO:0030321 7 7 0,000 9,683E-03 0,04245777 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 9,683E-03 0,0424068 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 9,683E-03 0,04235596 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 9,683E-03 0,04230523 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 9,683E-03 0,04225463 ! melanocyte differentiation GO:0030318 8 7 0,000 9,683E-03 0,04220414 ! malate dehydrogenase activity GO:0016615 8 7 0,000 9,683E-03 0,04215378 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 9,683E-03 0,04210354 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 9,683E-03 0,04205341 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 9,683E-03 0,04200341 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 9,683E-03 0,04195353 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 9,683E-03 0,04190376 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 9,683E-03 0,04185411 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 9,683E-03 0,04180458 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 9,683E-03 0,04175516 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 9,683E-03 0,04170587 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 9,683E-03 0,04165668 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 9,683E-03 0,04160762 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 9,683E-03 0,04155867 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 9,683E-03 0,04150983 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 9,683E-03 0,04146111 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 9,683E-03 0,04141251 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 9,683E-03 0,04136401 ! melanosome organization GO:0032438 7 7 0,000 9,683E-03 0,04131564 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 9,683E-03 0,04126737 ! mesodermal cell differentiation GO:0048333 9 7 0,000 9,683E-03 0,04121922 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 9,683E-03 0,04117118 ! Rac protein signal transduction GO:0016601 7 7 0,000 9,683E-03 0,04112325 ! chondrocyte differentiation GO:0002062 7 7 0,000 9,683E-03 0,04107543 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 9,683E-03 0,04102772 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 9,683E-03 0,04098013 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 9,683E-03 0,04093264 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 9,683E-03 0,04088526 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 9,683E-03 0,040838 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 9,683E-03 0,04079084 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 9,683E-03 0,04074379 ! Schwann cell differentiation GO:0014037 8 7 0,000 9,683E-03 0,04069685 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 9,683E-03 0,04065002 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 9,683E-03 0,0406033 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 9,683E-03 0,04055668 ! vinculin binding GO:0017166 9 7 0,000 9,683E-03 0,04051017 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 9,683E-03 0,04046377 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 9,683E-03 0,04041747 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 9,683E-03 0,04037128 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 9,683E-03 0,04032519 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 9,683E-03 0,04027921 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 9,683E-03 0,04023334 ! cardiac muscle cell development GO:0055013 8 7 0,000 9,683E-03 0,04018756 ! fibrinolysis GO:0042730 9 7 0,000 9,683E-03 0,0401419 ! response to tropane GO:0014073 10 7 0,000 9,683E-03 0,04009633 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 9,683E-03 0,04005087 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 9,683E-03 0,04000551 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 9,683E-03 0,03996026 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 9,683E-03 0,03991511 ! laminin-1 complex GO:0005606 7 7 0,000 9,683E-03 0,03987005 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 9,683E-03 0,03982511 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 9,683E-03 0,03978026 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 9,683E-03 0,03973551 ! regulation of cell division GO:0051302 7 7 0,000 9,683E-03 0,03969086 ! holo TFIIH complex GO:0005675 7 7 0,000 9,683E-03 0,03964632 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 9,683E-03 0,03960187 ! chitinase activity GO:0004568 7 7 0,000 9,683E-03 0,03955752 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 9,683E-03 0,03951328 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 9,683E-03 0,03946913 ! regulation of respiratory burst GO:0060263 8 7 0,000 9,683E-03 0,03942508 ! prophase GO:0051324 8 7 0,000 9,683E-03 0,03938112 ! peptidyl-histidine modification GO:0018202 8 7 0,000 9,683E-03 0,03933727 ! centriolar satellite GO:0034451 10 7 0,000 9,683E-03 0,03929351 ! BBSome GO:0034464 7 7 0,000 9,683E-03 0,03924985 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 9,683E-03 0,03920629 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,683E-03 0,03916283 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 9,683E-03 0,03911946 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 9,683E-03 0,03907618 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 9,683E-03 0,039033 ! regulation of synaptogenesis GO:0051963 7 7 0,000 9,683E-03 0,03898992 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 9,683E-03 0,03894693 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 9,683E-03 0,03890404 ! glycolipid catabolic process GO:0019377 7 7 0,000 9,683E-03 0,03886124 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 9,683E-03 0,03881854 ! circadian behavior GO:0048512 9 7 0,000 9,683E-03 0,03877593 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 9,683E-03 0,03873341 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 9,683E-03 0,03869098 ! striatum development GO:0021756 7 7 0,000 9,683E-03 0,03864865 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 9,683E-03 0,03860641 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 9,683E-03 0,03856427 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 9,683E-03 0,03852221 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 9,683E-03 0,03848025 ! dystroglycan complex GO:0016011 9 7 0,000 9,683E-03 0,03843838 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 9,683E-03 0,0383966 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 9,683E-03 0,03835491 ! peroxiredoxin activity GO:0051920 7 7 0,000 9,683E-03 0,03831331 ! muscle adaptation GO:0043500 7 7 0,000 9,683E-03 0,0382718 ! regulation of muscle adaptation GO:0043502 7 7 0,000 9,683E-03 0,03823038 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 9,683E-03 0,03818905 ! lysogeny GO:0030069 7 7 0,000 9,683E-03 0,03814781 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 9,683E-03 0,03810665 ! sequestering of metal ion GO:0051238 9 7 0,000 9,683E-03 0,03806559 ! membrane attack complex GO:0005579 7 7 0,000 9,683E-03 0,03802462 ! fibrinogen complex GO:0005577 7 7 0,000 9,683E-03 0,03798373 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 9,683E-03 0,03794293 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 9,683E-03 0,03790222 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 9,683E-03 0,0378616 ! GABA receptor binding GO:0050811 8 7 0,000 9,683E-03 0,03782106 ! sheet-forming collagen GO:0030935 7 7 0,000 9,683E-03 0,03778061 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 9,683E-03 0,03774024 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 9,683E-03 0,03769997 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 9,683E-03 0,03765977 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 9,683E-03 0,03761967 ! 7S RNA binding GO:0008312 8 7 0,000 9,683E-03 0,03757965 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 9,683E-03 0,03753971 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 9,683E-03 0,03749986 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 9,683E-03 0,03746009 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 9,683E-03 0,03742041 ! Golgi to endosome transport GO:0006895 8 7 0,000 9,683E-03 0,03738081 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 9,683E-03 0,0373413 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 9,683E-03 0,03730187 ! fibril GO:0043205 7 7 0,000 9,683E-03 0,03726252 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 9,683E-03 0,03722325 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 9,683E-03 0,03718407 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 9,683E-03 0,03714497 ! sensory perception of bitter taste GO:0050913 7 7 0,000 9,683E-03 0,03710595 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 9,683E-03 0,03706702 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 9,683E-03 0,03702816 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 9,683E-03 0,03698939 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 9,683E-03 0,0369507 ! equilibrioception GO:0050957 10 7 0,000 9,683E-03 0,03691209 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 9,683E-03 0,03687356 ! titin binding GO:0031432 7 7 0,000 9,683E-03 0,03683511 ! chemosensory behavior GO:0007635 9 7 0,000 9,683E-03 0,03679674 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 9,683E-03 0,03675845 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 9,683E-03 0,03672024 ! cobalamin binding GO:0031419 7 7 0,000 9,683E-03 0,03668211 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 9,683E-03 0,03664405 ! response to axon injury GO:0048678 9 7 0,000 9,683E-03 0,03660608 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 9,683E-03 0,03656819 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 9,683E-03 0,03653037 ! F-actin capping protein complex GO:0008290 8 7 0,000 9,683E-03 0,03649263 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 9,683E-03 0,03645497 ! cGMP-mediated signaling GO:0019934 8 7 0,000 9,683E-03 0,03641739 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 9,683E-03 0,03637989 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 9,683E-03 0,03634246 ! senescence GO:0010149 8 7 0,000 9,683E-03 0,03630511 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 9,683E-03 0,03626783 ! galactose metabolic process GO:0006012 8 7 0,000 9,683E-03 0,03623063 ! vesicle fusion GO:0006906 8 7 0,000 9,683E-03 0,03619351 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 9,683E-03 0,03615647 ! intracellular pH reduction GO:0051452 7 7 0,000 9,683E-03 0,0361195 ! glycerol ether catabolic process GO:0044269 16 7 0,000 9,683E-03 0,0360826 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 9,683E-03 0,03604578 ! ruffle organization GO:0031529 9 7 0,000 9,683E-03 0,03600904 ! nucleoside transport GO:0015858 8 7 0,000 9,683E-03 0,03597237 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 9,683E-03 0,03593578 ! inclusion body GO:0016234 7 7 0,000 9,683E-03 0,03589926 ! Cajal body GO:0015030 7 7 0,000 9,683E-03 0,03586281 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 9,683E-03 0,03582644 ! rRNA modification GO:0000154 7 7 0,000 9,683E-03 0,03579014 ! PcG protein complex GO:0031519 7 7 0,000 9,683E-03 0,03575392 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 9,683E-03 0,03571776 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 9,683E-03 0,03568169 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 9,683E-03 0,03564568 ! apolipoprotein binding GO:0034185 9 7 0,000 9,683E-03 0,03560975 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 9,683E-03 0,03557389 ! segment specification GO:0007379 9 7 0,000 9,683E-03 0,0355381 ! pronucleus GO:0045120 25 7 0,000 9,683E-03 0,03550238 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 9,683E-03 0,03546674 ! Rac GTPase activator activity GO:0030675 9 7 0,000 9,683E-03 0,03543116 ! regulation of DNA repair GO:0006282 19 7 0,000 9,683E-03 0,03539566 ! preribosome GO:0030684 7 7 0,000 9,683E-03 0,03536023 ! DNA topological change GO:0006265 7 7 0,000 9,683E-03 0,03532487 ! DNA ligation GO:0006266 8 7 0,000 9,683E-03 0,03528958 ! hair follicle maturation GO:0048820 8 7 0,000 9,683E-03 0,03525436 ! renal water homeostasis GO:0003091 7 7 0,000 9,683E-03 0,03521921 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 9,683E-03 0,03518413 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 9,683E-03 0,03514912 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 9,683E-03 0,03511418 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 9,683E-03 0,03507931 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 9,683E-03 0,03504451 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 9,683E-03 0,03500978 ! phosphofructokinase activity GO:0008443 7 7 0,000 9,683E-03 0,03497512 ! gap junction channel activity GO:0005243 8 7 0,000 9,683E-03 0,03494052 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 9,683E-03 0,034906 ! histone methylation GO:0016571 7 7 0,000 9,683E-03 0,03487154 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 9,683E-03 0,03483715 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 9,683E-03 0,03480283 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 9,683E-03 0,03476857 ! muscle cell proliferation GO:0033002 8 7 0,000 9,683E-03 0,03473438 ! transcription termination GO:0006353 9 7 0,000 9,683E-03 0,03470026 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 0,000 9,683E-03 0,03466621 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 9,683E-03 0,03463222 ! cytidylyltransferase activity GO:0070567 8 7 0,000 9,683E-03 0,0345983 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 9,683E-03 0,03456445 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 9,683E-03 0,03453066 ! salivary gland development GO:0007431 7 7 0,000 9,683E-03 0,03449694 ! glucosidase activity GO:0015926 8 7 0,000 9,683E-03 0,03446329 ! NuRD complex GO:0016581 8 7 0,000 9,683E-03 0,0344297 ! negative regulation of nuclear division GO:0051784 7 7 0,000 9,683E-03 0,03439617 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 9,683E-03 0,03436271 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 9,683E-03 0,03432932 ! response to redox state GO:0051775 8 7 0,000 9,683E-03 0,03429599 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 9,683E-03 0,03426272 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 9,683E-03 0,03422952 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 9,683E-03 0,03419639 ! actin monomer binding GO:0003785 7 7 0,000 9,683E-03 0,03416332 ! protein prenyltransferase activity GO:0008318 8 7 0,000 9,683E-03 0,03413031 ! endosome to lysosome transport GO:0008333 7 7 0,000 9,683E-03 0,03409736 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 9,683E-03 0,03406448 ! germ cell migration GO:0008354 7 7 0,000 9,683E-03 0,03403167 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 9,683E-03 0,03399891 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 9,683E-03 0,03396622 ! CoA-ligase activity GO:0016405 8 7 0,000 9,683E-03 0,03393359 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 9,683E-03 0,03390103 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 9,683E-03 0,03386852 ! embryonic heart tube development GO:0035050 8 7 0,000 9,683E-03 0,03383608 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 9,683E-03 0,0338037 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 9,683E-03 0,03377138 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 9,683E-03 0,03373913 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 9,683E-03 0,03370694 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 9,683E-03 0,0336748 ! adenylate kinase activity GO:0004017 8 7 0,000 9,683E-03 0,03364273 ! negative regulation of immune effector process GO:0002698 13 7 0,000 9,683E-03 0,03361072 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 9,683E-03 0,03357877 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 9,683E-03 0,03354688 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 0,01105931 0,03827737 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 0,01105931 0,03824109 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 0,01105931 0,03820488 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 0,01105931 0,03816873 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 0,000 0,01105931 0,03813266 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 0,01105931 0,03809665 ! proteasome regulatory particle GO:0005838 8 8 0,000 0,01105931 0,03806071 ! SMAD protein complex assembly GO:0007183 10 8 0,000 0,01105931 0,03802483 ! protein self-association GO:0043621 8 8 0,000 0,01105931 0,03798903 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 0,01105931 0,03795329 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 0,01105931 0,03791762 ! neurotransmitter uptake GO:0001504 8 8 0,000 0,01105931 0,03788202 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 0,01105931 0,03784648 ! guanylate cyclase activity GO:0004383 9 8 0,000 0,01105931 0,03781101 ! troponin complex GO:0005861 8 8 0,000 0,01105931 0,03777561 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 0,01105931 0,03774027 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 0,01105931 0,037705 ! keratinocyte proliferation GO:0043616 9 8 0,000 0,01105931 0,03766979 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 0,01105931 0,03763465 ! microtubule bundle formation GO:0001578 8 8 0,000 0,01105931 0,03759958 ! middle ear morphogenesis GO:0042474 10 8 0,000 0,01105931 0,03756457 ! ganglioside metabolic process GO:0001573 8 8 0,000 0,01105931 0,03752963 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 0,01105931 0,03749475 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 0,01105931 0,03745993 ! ciliary or flagellar motility GO:0001539 8 8 0,000 0,01105931 0,03742519 ! pathogenesis GO:0009405 8 8 0,000 0,01105931 0,0373905 ! pH reduction GO:0045851 9 8 0,000 0,01105931 0,03735588 ! small protein activating enzyme activity GO:0008641 10 8 0,000 0,01105931 0,03732132 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 0,01105931 0,03728683 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 0,01105931 0,0372524 ! hemoglobin metabolic process GO:0020027 8 8 0,000 0,01105931 0,03721803 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 0,01105931 0,03718373 ! arginine catabolic process GO:0006527 9 8 0,000 0,01105931 0,03714949 ! T-tubule GO:0030315 9 8 0,000 0,01105931 0,03711532 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 0,01105931 0,0370812 ! histidine catabolic process GO:0006548 8 8 0,000 0,01105931 0,03704715 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 0,01105931 0,03701316 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 0,01105931 0,03697924 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 0,01105931 0,03694538 ! proline metabolic process GO:0006560 10 8 0,000 0,01105931 0,03691157 ! L-serine metabolic process GO:0006563 9 8 0,000 0,01105931 0,03687783 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 0,01105931 0,03684415 ! melanosome membrane GO:0033162 9 8 0,000 0,01105931 0,03681054 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01105931 0,03677698 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 0,01105931 0,03674349 ! pericentriolar material GO:0000242 9 8 0,000 0,01105931 0,03671005 ! reverse cholesterol transport GO:0043691 8 8 0,000 0,01105931 0,03667668 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 0,01105931 0,03664337 ! melanin metabolic process GO:0006582 10 8 0,000 0,01105931 0,03661012 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 0,01105931 0,03657693 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 0,01105931 0,03654379 ! Golgi lumen GO:0005796 8 8 0,000 0,01105931 0,03651072 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 0,01105931 0,03647771 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 0,01105931 0,03644476 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 0,01105931 0,03641187 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 0,01105931 0,03637903 ! stereocilium bundle GO:0032421 11 8 0,000 0,01105931 0,03634626 ! forebrain cell migration GO:0021885 9 8 0,000 0,01105931 0,03631355 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 0,01105931 0,03628089 ! osteoblast development GO:0002076 11 8 0,000 0,01105931 0,03624829 ! retinoic acid metabolic process GO:0042573 8 8 0,000 0,01105931 0,03621575 ! retinol metabolic process GO:0042572 8 8 0,000 0,01105931 0,03618327 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 0,01105931 0,03615085 ! structural constituent of epidermis GO:0030280 9 8 0,000 0,01105931 0,03611849 ! clathrin binding GO:0030276 10 8 0,000 0,01105931 0,03608618 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 0,01105931 0,03605393 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 0,01105931 0,03602174 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 0,01105931 0,03598961 ! motor axon guidance GO:0008045 8 8 0,000 0,01105931 0,03595753 ! protein targeting to vacuole GO:0006623 8 8 0,000 0,01105931 0,03592551 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 0,01105931 0,03589355 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 0,01105931 0,03586164 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 0,01105931 0,0358298 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 0,01105931 0,035798 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01105931 0,03576627 ! protein-lipid complex assembly GO:0065005 8 8 0,000 0,01105931 0,03573459 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 0,01105931 0,03570296 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 0,01105931 0,0356714 ! regulation of dopamine secretion GO:0014059 9 8 0,000 0,01105931 0,03563988 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 0,01105931 0,03560843 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 0,01105931 0,03557703 ! subpallium development GO:0021544 8 8 0,000 0,01105931 0,03554568 ! positive regulation of Rho GTPase activity GO:0032321 11 8 0,000 0,01105931 0,03551439 ! icosanoid secretion GO:0032309 10 8 0,000 0,01105931 0,03548316 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 0,01105931 0,03545198 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 0,01105931 0,03542085 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 0,01105931 0,03538978 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 0,01105931 0,03535876 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 0,01105931 0,0353278 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 0,01105931 0,03529689 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 0,01105931 0,03526604 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 0,01105931 0,03523524 ! ubiquinone metabolic process GO:0006743 9 8 0,000 0,01105931 0,03520449 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 0,01105931 0,0351738 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 0,01105931 0,03514316 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 0,01105931 0,03511258 ! Wnt receptor activity GO:0042813 11 8 0,000 0,01105931 0,03508204 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 0,01105931 0,03505156 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 0,01105931 0,03502114 ! detection of calcium ion GO:0005513 9 8 0,000 0,01105931 0,03499076 ! negative regulation of glucose import GO:0046325 9 8 0,000 0,01105931 0,03496044 ! blastocyst growth GO:0001832 8 8 0,000 0,01105931 0,03493017 ! regulation of fibrinolysis GO:0051917 8 8 0,000 0,01105931 0,03489996 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 0,01105931 0,03486979 ! cerebellar cortex formation GO:0021697 9 8 0,000 0,01105931 0,03483968 ! complement binding GO:0001848 11 8 0,000 0,01105931 0,03480962 ! regulation of actin filament bundle formation GO:0032231 13 8 0,000 0,01105931 0,03477961 GO:0051492|regulation of stress fiber formation, ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 0,01105931 0,03474966 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 0,01105931 0,03471975 ! amino sugar catabolic process GO:0046348 8 8 0,000 0,01105931 0,0346899 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 0,01105931 0,03466009 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 0,01105931 0,03463034 ! positive regulation of amine transport GO:0051954 9 8 0,000 0,01105931 0,03460064 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 0,01105931 0,03457099 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 0,01105931 0,0345414 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01105931 0,03451185 ! Golgi transport complex GO:0017119 8 8 0,000 0,01105931 0,03448235 ! positive regulation of protein ubiquitination GO:0031398 17 8 0,000 0,01105931 0,0344529 ! GDP binding GO:0019003 9 8 0,000 0,01105931 0,03442351 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 0,01105931 0,03439416 ! prostate gland development GO:0030850 17 8 0,000 0,01105931 0,03436486 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 0,01105931 0,03433562 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 0,01105931 0,03430642 ! phosphate transport GO:0006817 9 8 0,000 0,01105931 0,03427727 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 0,01105931 0,03424817 ! oligopeptide transport GO:0006857 8 8 0,000 0,01105931 0,03421913 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 0,01105931 0,03419013 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 0,01105931 0,03416118 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 0,01105931 0,03413228 ! lipoprotein transport GO:0042953 9 8 0,000 0,01105931 0,03410342 ! estrogen metabolic process GO:0008210 8 8 0,000 0,01105931 0,03407462 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 0,01105931 0,03404586 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 0,01105931 0,03401716 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 0,01105931 0,0339885 ! T-helper 1 type immune response GO:0042088 8 8 0,000 0,01105931 0,03395989 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 0,01105931 0,03393133 ! response to amphetamine GO:0001975 11 8 0,000 0,01105931 0,03390281 ! mechanosensory behavior GO:0007638 8 8 0,000 0,01105931 0,03387435 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 0,01105931 0,03384593 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 0,01105931 0,03381756 ! C-X-C chemokine binding GO:0019958 8 8 0,000 0,01105931 0,03378924 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 0,01105931 0,03376096 ! glycerolipid catabolic process GO:0046503 17 8 0,000 0,01105931 0,03373273 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 0,01105931 0,03370455 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 0,01105931 0,03367642 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 0,01105931 0,03364833 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 0,01105931 0,03362029 ! pigment granule organization GO:0048753 9 8 0,000 0,01105931 0,0335923 ! GTP-dependent protein binding GO:0030742 11 8 0,000 0,01105931 0,03356435 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 0,01105931 0,03353645 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 0,01105931 0,0335086 ! regulation of pigmentation during development GO:0048070 11 8 0,000 0,01105931 0,03348079 ! macrophage activation GO:0042116 8 8 0,000 0,01105931 0,03345303 ! poly(A) RNA binding GO:0008143 8 8 0,000 0,01105931 0,03342531 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 0,01105931 0,03339764 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 0,01105931 0,03337002 ! asymmetric protein localization GO:0008105 9 8 0,000 0,01105931 0,03334244 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 0,01105931 0,0333149 ! neurotrophin binding GO:0043121 10 8 0,000 0,01105931 0,03328742 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 0,01105931 0,03325997 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 0,01105931 0,03323258 ! phagocytosis, engulfment GO:0006911 10 8 0,000 0,01105931 0,03320523 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 0,01105931 0,03317792 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 0,01105931 0,03315066 ! UV protection GO:0009650 9 8 0,000 0,01105931 0,03312344 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 0,01105931 0,03309627 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 0,01105931 0,03306914 ! glutathione peroxidase activity GO:0004602 17 8 0,000 0,01105931 0,03304206 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 0,01105931 0,03301502 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 0,01105931 0,03298802 ! ferric iron binding GO:0008199 9 8 0,000 0,01105931 0,03296107 ! response to UV-B GO:0010224 10 8 0,000 0,01105931 0,03293416 ! intermediate filament organization GO:0045109 8 8 0,000 0,01105931 0,0329073 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 0,01105931 0,03288048 ! cellular extravasation GO:0045123 9 8 0,000 0,01105931 0,0328537 ! skeletal muscle contraction GO:0003009 8 8 0,000 0,01105931 0,03282697 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 0,01105931 0,03280028 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 0,000 0,01105931 0,03277364 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01105931 0,03274704 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 0,01105931 0,03272048 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 0,01105931 0,03269396 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 0,01105931 0,03266749 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 0,01105931 0,03264106 ! erythrocyte development GO:0048821 9 8 0,000 0,01105931 0,03261467 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 0,01105931 0,03258833 ! ribosome assembly GO:0042255 8 8 0,000 0,01105931 0,03256203 ! postreplication repair GO:0006301 19 8 0,000 0,01105931 0,03253577 ! gamma-tubulin binding GO:0043015 8 8 0,000 0,01105931 0,03250955 ! NADPH oxidase complex GO:0043020 8 8 0,000 0,01105931 0,03248337 ! mRNA cleavage GO:0006379 9 8 0,000 0,01105931 0,03245724 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 0,01105931 0,03243115 ! opioid receptor activity GO:0004985 8 8 0,000 0,01105931 0,0324051 ! zymogen activation GO:0031638 9 8 0,000 0,01105931 0,03237909 ! coenzyme A metabolic process GO:0015936 8 8 0,000 0,01105931 0,03235313 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 0,01105931 0,0323272 ! costamere GO:0043034 8 8 0,000 0,01105931 0,03230132 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 0,01105931 0,03227548 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 0,01105931 0,03224968 ! sarcomere organization GO:0045214 9 8 0,000 0,01105931 0,03222392 ! wide pore channel activity GO:0022829 9 8 0,000 0,01105931 0,0321982 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 0,01105931 0,03217253 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 0,01105931 0,03214689 ! hormone catabolic process GO:0042447 9 8 0,000 0,01105931 0,0321213 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 0,01105931 0,03209574 ! cGMP biosynthetic process GO:0006182 9 8 0,000 0,01105931 0,03207023 ! lysozyme activity GO:0003796 10 8 0,000 0,01105931 0,03204476 ! death receptor binding GO:0005123 8 8 0,000 0,01105931 0,03201933 ! protein modification by small protein removal GO:0070646 9 8 0,000 0,01105931 0,03199393 ! adult feeding behavior GO:0008343 9 8 0,000 0,01105931 0,03196858 ! microtubule basal body GO:0005932 8 8 0,000 0,01105931 0,03194327 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 0,01105931 0,031918 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 0,01105931 0,03189277 ! calcium-release channel activity GO:0015278 8 8 0,000 0,01105931 0,03186757 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 0,01105931 0,03184242 ! behavioral response to nicotine GO:0035095 9 8 0,000 0,01105931 0,03181731 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 0,01105931 0,03179224 ! adenosine deaminase activity GO:0004000 8 8 0,000 0,01105931 0,0317672 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 0,01243342 0,03568617 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 0,01243342 0,03565812 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 0,01243342 0,03563011 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 0,01243342 0,03560214 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 0,01243342 0,03557422 ! myotube differentiation GO:0014902 9 9 0,000 0,01243342 0,03554634 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 0,01243342 0,0355185 ! N-glycan processing GO:0006491 10 9 0,000 0,01243342 0,03549071 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 0,01243342 0,03546296 ! actin-myosin filament sliding GO:0033275 11 9 0,000 0,01243342 0,03543525 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 0,01243342 0,03540759 ! RNA methylation GO:0001510 9 9 0,000 0,01243342 0,03537997 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 0,01243342 0,0353524 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 0,01243342 0,03532486 ! artery development GO:0060840 9 9 0,000 0,01243342 0,03529737 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 0,01243342 0,03526993 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 0,01243342 0,03524252 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 0,01243342 0,03521516 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 0,01243342 0,03518784 ! positive regulation of heart contraction GO:0045823 11 9 0,000 0,01243342 0,03516056 ! lipopolysaccharide binding GO:0001530 9 9 0,000 0,01243342 0,03513333 ! regulated secretory pathway GO:0045055 10 9 0,000 0,01243342 0,03510613 ! estrogen receptor binding GO:0030331 9 9 0,000 0,01243342 0,03507898 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 0,01243342 0,03505187 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 0,01243342 0,03502481 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 0,01243342 0,03499778 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 0,01243342 0,0349708 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 0,000 0,01243342 0,03494386 ! urea metabolic process GO:0019627 19 9 0,000 0,01243342 0,03491696 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 0,01243342 0,0348901 ! autophagic vacuole GO:0005776 11 9 0,000 0,01243342 0,03486328 ! Rac GTPase binding GO:0048365 10 9 0,000 0,01243342 0,0348365 ! response to dietary excess GO:0002021 9 9 0,000 0,01243342 0,03480977 ! regulation of sodium ion transport GO:0002028 10 9 0,000 0,01243342 0,03478307 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01243342 0,03475642 ! lens development in camera-type eye GO:0002088 9 9 0,000 0,01243342 0,0347298 ! male sex determination GO:0030238 9 9 0,000 0,01243342 0,03470323 ! positive regulation of vasodilation GO:0045909 19 9 0,000 0,01243342 0,0346767 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 0,01243342 0,03465021 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 0,01243342 0,03462376 ! male germ cell nucleus GO:0001673 11 9 0,000 0,01243342 0,03459735 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 0,01243342 0,03457098 ! copper ion homeostasis GO:0055070 9 9 0,000 0,01243342 0,03454465 ! protein heterooligomerization GO:0051291 10 9 0,000 0,01243342 0,03451836 ! spectrin GO:0008091 9 9 0,000 0,01243342 0,03449211 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 0,01243342 0,0344659 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 0,01243342 0,03443973 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 0,01243342 0,0344136 ! regulation of B cell differentiation GO:0045577 10 9 0,000 0,01243342 0,03438751 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 0,01243342 0,03436146 ! neural tube patterning GO:0021532 10 9 0,000 0,01243342 0,03433545 ! fucose catabolic process GO:0019317 10 9 0,000 0,01243342 0,03430947 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 0,01243342 0,03428354 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 0,01243342 0,03425765 ! sterol catabolic process GO:0016127 10 9 0,000 0,01243342 0,03423179 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 0,01243342 0,03420598 ! clathrin coat of coated pit GO:0030132 11 9 0,000 0,01243342 0,0341802 ! SNARE complex GO:0031201 11 9 0,000 0,01243342 0,03415446 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 0,01243342 0,03412876 ! negative regulation of glucose transport GO:0010829 10 9 0,000 0,01243342 0,0341031 ! methionine biosynthetic process GO:0009086 11 9 0,000 0,01243342 0,03407748 ! peptidoglycan binding GO:0042834 9 9 0,000 0,01243342 0,0340519 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 0,01243342 0,03402635 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 0,01243342 0,03400084 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 0,01243342 0,03397537 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 0,01243342 0,03394994 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 0,01243342 0,03392455 ! detection of bacterium GO:0016045 10 9 0,000 0,01243342 0,0338992 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 0,01243342 0,03387388 ! embryonic gut development GO:0048566 10 9 0,000 0,01243342 0,0338486 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 0,01243342 0,03382336 ! desmosome GO:0030057 10 9 0,000 0,01243342 0,03379816 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 0,01243342 0,03377299 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 0,01243342 0,03374786 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 0,01243342 0,03372277 ! actin filament polymerization GO:0030041 10 9 0,000 0,01243342 0,03369772 ! negative regulation of B cell activation GO:0050869 10 9 0,000 0,01243342 0,0336727 ! establishment of cell polarity GO:0030010 10 9 0,000 0,01243342 0,03364772 ! regulation of synapse organization GO:0050807 10 9 0,000 0,01243342 0,03362278 ! septin complex GO:0031105 10 9 0,000 0,01243342 0,03359787 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 0,01243342 0,033573 ! anchoring collagen GO:0030934 9 9 0,000 0,01243342 0,03354817 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 0,01243342 0,03352337 ! regulation of developmental growth GO:0048638 11 9 0,000 0,01243342 0,03349861 ! GMP binding GO:0019002 11 9 0,000 0,01243342 0,03347389 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 0,01243342 0,03344921 ! virus-host interaction GO:0019048 13 9 0,000 0,01243342 0,03342456 ! pentose-phosphate shunt GO:0006098 11 9 0,000 0,01243342 0,03339994 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 0,01243342 0,03337537 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 0,01243342 0,03335083 ! non-recombinational repair GO:0000726 10 9 0,000 0,01243342 0,03332632 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 0,01243342 0,03330185 ! nuclear telomere cap complex GO:0000783 10 9 0,000 0,01243342 0,03327742 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 0,01243342 0,03325302 ! social behavior GO:0035176 10 9 0,000 0,01243342 0,03322866 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 0,01243342 0,03320434 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 0,01243342 0,03318005 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 0,01243342 0,03315579 ! mating GO:0007618 11 9 0,000 0,01243342 0,03313157 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 0,01243342 0,03310739 ! rhythmic behavior GO:0007622 11 9 0,000 0,01243342 0,03308324 ! phospholipid efflux GO:0033700 10 9 0,000 0,01243342 0,03305913 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 0,01243342 0,03303505 ! poly-purine tract binding GO:0070717 9 9 0,000 0,01243342 0,03301101 ! T cell proliferation GO:0042098 10 9 0,000 0,01243342 0,032987 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 0,01243342 0,03296303 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 0,01243342 0,03293909 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 0,01243342 0,03291518 ! interleukin-1 binding GO:0019966 10 9 0,000 0,01243342 0,03289132 ! glucosyltransferase activity GO:0046527 9 9 0,000 0,01243342 0,03286748 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 0,01243342 0,03284368 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 0,01243342 0,03281992 ! ovulation GO:0030728 9 9 0,000 0,01243342 0,03279619 ! acid phosphatase activity GO:0003993 18 9 0,000 0,01243342 0,03277249 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 0,01243342 0,03274883 ! ER overload response GO:0006983 11 9 0,000 0,01243342 0,0327252 ! B cell proliferation GO:0042100 10 9 0,000 0,01243342 0,0327016 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 0,01243342 0,03267804 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 0,01243342 0,03265452 ! mannose metabolic process GO:0006013 13 9 0,000 0,01243342 0,03263102 ! lipid digestion GO:0044241 11 9 0,000 0,01243342 0,03260757 ! tumor necrosis factor binding GO:0043120 9 9 0,000 0,01243342 0,03258414 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 0,01243342 0,03256075 ! regulation of bone resorption GO:0045124 10 9 0,000 0,01243342 0,03253739 ! brain morphogenesis GO:0048854 9 9 0,000 0,01243342 0,03251407 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 0,01243342 0,03249078 ! synaptic vesicle membrane GO:0030672 9 9 0,000 0,01243342 0,03246752 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 0,01243342 0,0324443 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 0,01243342 0,0324211 ! kinesin binding GO:0019894 9 9 0,000 0,01243342 0,03239795 ! multicellular organismal aging GO:0010259 18 9 0,000 0,01243342 0,03237482 ! Ran GTPase binding GO:0008536 11 9 0,000 0,01243342 0,03235173 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 0,01243342 0,03232867 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 0,01243342 0,03230564 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 0,01243342 0,03228265 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 0,01243342 0,03225969 ! prostaglandin receptor activity GO:0004955 11 9 0,000 0,01243342 0,03223676 ! caspase inhibitor activity GO:0043027 9 9 0,000 0,01243342 0,03221387 ! adrenoceptor activity GO:0004935 12 9 0,000 0,01243342 0,032191 ! regulation of isotype switching GO:0045191 9 9 0,000 0,01243342 0,03216817 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 0,01243342 0,03214538 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 0,01243342 0,03212261 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 0,01243342 0,03209988 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 0,01243342 0,03207717 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 0,01243342 0,03205451 ! Notch binding GO:0005112 10 9 0,000 0,01243342 0,03203187 ! ATPase regulator activity GO:0060590 10 9 0,000 0,01243342 0,03200926 ! gamma-tubulin complex GO:0000930 19 9 0,000 0,01243342 0,03198669 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 0,01243342 0,03196415 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 0,01243342 0,03194164 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 0,01243342 0,03191916 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 0,01243342 0,03189671 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 0,000 0,0138057 0,03539227 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,0138057 0,03536742 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,0138057 0,0353426 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,0138057 0,03531781 ! sleep GO:0030431 11 10 0,000 0,0138057 0,03529306 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,0138057 0,03526835 ! lipid particle GO:0005811 10 10 0,000 0,0138057 0,03524367 ! filopodium assembly GO:0046847 14 10 0,000 0,0138057 0,03521902 ! UTP metabolic process GO:0046051 12 10 0,000 0,0138057 0,03519441 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,0138057 0,03516983 ! guanylate kinase activity GO:0004385 14 10 0,000 0,0138057 0,03514529 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,0138057 0,03512078 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,0138057 0,03509631 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,0138057 0,03507187 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,0138057 0,03504746 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,0138057 0,03502309 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,0138057 0,03499875 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,0138057 0,03497445 ! lung alveolus development GO:0048286 11 10 0,000 0,0138057 0,03495017 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,0138057 0,03492594 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0138057 0,03490173 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,0138057 0,03487756 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,0138057 0,03485343 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,0138057 0,03482932 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,0138057 0,03480525 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,0138057 0,03478122 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,0138057 0,03475721 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,0138057 0,03473324 ! histidine metabolic process GO:0006547 10 10 0,000 0,0138057 0,03470931 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,0138057 0,0346854 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,0138057 0,03466153 ! death receptor activity GO:0005035 11 10 0,000 0,0138057 0,03463769 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,0138057 0,03461388 ! entry into host cell GO:0030260 11 10 0,000 0,0138057 0,03459011 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,0138057 0,03456637 ! filamentous actin GO:0031941 11 10 0,000 0,0138057 0,03454266 ! behavioral fear response GO:0001662 12 10 0,000 0,0138057 0,03451899 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,0138057 0,03449534 ! negative regulation of ossification GO:0030279 12 10 0,000 0,0138057 0,03447173 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,0138057 0,03444815 ! macrophage differentiation GO:0030225 11 10 0,000 0,0138057 0,03442461 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,0138057 0,03440109 ! recycling endosome membrane GO:0055038 11 10 0,000 0,0138057 0,03437761 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,0138057 0,03435416 ! snRNA metabolic process GO:0016073 10 10 0,000 0,0138057 0,03433074 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,0138057 0,03430736 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 0,0138057 0,034284 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,0138057 0,03426068 ! positive regulation of Ras GTPase activity GO:0032320 14 10 0,000 0,0138057 0,03423739 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,0138057 0,03421413 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,0138057 0,0341909 ! induction of an organ GO:0001759 12 10 0,000 0,0138057 0,03416771 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,0138057 0,03414454 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,0138057 0,03412141 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,0138057 0,03409831 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,0138057 0,03407524 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,0138057 0,0340522 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,0138057 0,03402919 ! ribonuclease P activity GO:0004526 10 10 0,000 0,0138057 0,03400621 ! COPI vesicle coat GO:0030126 12 10 0,000 0,0138057 0,03398327 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,0138057 0,03396035 ! vitamin transporter activity GO:0051183 12 10 0,000 0,0138057 0,03393747 ! snRNA binding GO:0017069 11 10 0,000 0,0138057 0,03391461 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,0138057 0,03389179 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,0138057 0,033869 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,0138057 0,03384624 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,0138057 0,03382351 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,0138057 0,03380081 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,0138057 0,03377814 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,0138057 0,0337555 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,0138057 0,03373289 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,0138057 0,03371031 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,0138057 0,03368776 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 0,0138057 0,03366524 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 0,0138057 0,03364275 ! extracellular matrix binding GO:0050840 11 10 0,000 0,0138057 0,0336203 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,0138057 0,03359787 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,0138057 0,03357547 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,0138057 0,0335531 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,0138057 0,03353076 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 0,0138057 0,03350845 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,0138057 0,03348617 ! thyroid gland development GO:0030878 12 10 0,000 0,0138057 0,03346392 ! DNA bending activity GO:0008301 11 10 0,000 0,0138057 0,0334417 ! regulation of phosphatase activity GO:0010921 10 10 0,000 0,0138057 0,03341951 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,0138057 0,03339735 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,0138057 0,03337522 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,0138057 0,03335311 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,0138057 0,03333104 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,0138057 0,033309 ! regulation of glycolysis GO:0006110 11 10 0,000 0,0138057 0,03328698 ! nucleotidase activity GO:0008252 10 10 0,000 0,0138057 0,03326499 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,0138057 0,03324304 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,0138057 0,03322111 ! androgen metabolic process GO:0008209 11 10 0,000 0,0138057 0,03319921 ! lateral plasma membrane GO:0016328 13 10 0,000 0,0138057 0,03317734 ! MAP kinase kinase activity GO:0004708 12 10 0,000 0,0138057 0,0331555 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,0138057 0,03313369 ! startle response GO:0001964 13 10 0,000 0,0138057 0,0331119 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,0138057 0,03309015 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,0138057 0,03306842 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 0,0138057 0,03304672 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,0138057 0,03302505 ! spinal cord patterning GO:0021511 12 10 0,000 0,0138057 0,03300341 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,0138057 0,0329818 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,0138057 0,03296021 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,0138057 0,03293865 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 0,0138057 0,03291713 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,0138057 0,03289563 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,0138057 0,03287415 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,0138057 0,03285271 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,0138057 0,03283129 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,0138057 0,0328099 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,0138057 0,03278854 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,0138057 0,03276721 ! adult heart development GO:0007512 14 10 0,000 0,0138057 0,03274591 ! neuromuscular junction development GO:0007528 12 10 0,000 0,0138057 0,03272463 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,0138057 0,03270338 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,0138057 0,03268216 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,0138057 0,03266096 ! signalosome GO:0008180 10 10 0,000 0,0138057 0,03263979 ! lysophospholipase activity GO:0004622 19 10 0,000 0,0138057 0,03261865 ! prefoldin complex GO:0016272 10 10 0,000 0,0138057 0,03259754 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,0138057 0,03257646 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,0138057 0,0325554 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,0138057 0,03253437 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,0138057 0,03251336 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,0138057 0,03249239 ! gland morphogenesis GO:0022612 11 10 0,000 0,0138057 0,03247144 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,0138057 0,03245052 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,0138057 0,03242962 ! peptide transporter activity GO:0015197 10 10 0,000 0,0138057 0,03240875 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,0138057 0,03238791 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,0138057 0,0323671 ! muscle maintenance GO:0046716 10 10 0,000 0,0138057 0,03234631 ! acid secretion GO:0046717 12 10 0,000 0,0138057 0,03232555 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,0138057 0,03230481 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,0138057 0,0322841 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,0138057 0,03226342 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,0138057 0,03224277 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,0138057 0,03222214 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,0138057 0,03220154 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,0138057 0,03218096 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,0138057 0,03216041 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 0,0138057 0,03213989 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,0138057 0,03211939 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,0138057 0,03209892 ! water channel activity GO:0015250 15 10 0,000 0,0138057 0,03207847 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,0138057 0,03205805 ! regulation of embryonic development GO:0045995 12 10 0,000 0,0138057 0,03203766 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 0,000 0,0138057 0,03201729 ! acrosome reaction GO:0007340 12 10 0,000 0,0138057 0,03199695 ! mitochondrion localization GO:0051646 10 10 0,000 0,0138057 0,03197664 ! cilium part GO:0044441 10 10 0,000 0,0138057 0,03195635 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,01517615 0,03510627 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,01517615 0,03508402 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,01517615 0,03506181 ! centriole GO:0005814 11 11 0,000 0,01517615 0,03503961 ! cadmium ion binding GO:0046870 15 11 0,000 0,01517615 0,03501745 ! hemoglobin complex GO:0005833 13 11 0,000 0,01517615 0,03499532 ! CTP metabolic process GO:0046036 13 11 0,000 0,01517615 0,03497321 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,01517615 0,03495113 ! response to pain GO:0048265 12 11 0,000 0,01517615 0,03492908 ! regulation of viral genome replication GO:0045069 13 11 0,000 0,01517615 0,03490706 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,01517615 0,03488506 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,01517615 0,03486309 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,01517615 0,03484115 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,01517615 0,03481924 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01517615 0,03479735 ! peptide antigen binding GO:0042605 14 11 0,000 0,01517615 0,0347755 ! polyamine metabolic process GO:0006595 11 11 0,000 0,01517615 0,03475367 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,01517615 0,03473186 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,01517615 0,03471009 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,01517615 0,03468834 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,01517615 0,03466662 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,01517615 0,03464493 ! protein homotetramerization GO:0051289 13 11 0,000 0,01517615 0,03462326 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,01517615 0,03460162 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,01517615 0,03458001 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,01517615 0,03455842 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,01517615 0,03453686 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,01517615 0,03451533 ! response to dsRNA GO:0043331 21 11 0,000 0,01517615 0,03449383 ! response to amine stimulus GO:0014075 15 11 0,000 0,01517615 0,03447235 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,01517615 0,0344509 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,01517615 0,03442947 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,01517615 0,03440807 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,01517615 0,0343867 ! retinal binding GO:0016918 11 11 0,000 0,01517615 0,03436536 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,01517615 0,03434404 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,01517615 0,03432275 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,01517615 0,03430148 ! autonomic nervous system development GO:0048483 12 11 0,000 0,01517615 0,03428024 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,01517615 0,03425903 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,01517615 0,03423784 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,01517615 0,03421668 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,01517615 0,03419555 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,01517615 0,03417444 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,01517615 0,03415336 ! regulation of epidermis development GO:0045682 14 11 0,000 0,01517615 0,0341323 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,01517615 0,03411127 ! midbrain development GO:0030901 12 11 0,000 0,01517615 0,03409027 ! musculoskeletal movement GO:0050881 12 11 0,000 0,01517615 0,03406929 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 0,01517615 0,03404833 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,01517615 0,03402741 ! cell killing GO:0001906 13 11 0,000 0,01517615 0,03400651 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,01517615 0,03398563 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,01517615 0,03396478 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,01517615 0,03394395 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 0,01517615 0,03392316 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 0,01517615 0,03390238 ! folic acid binding GO:0005542 12 11 0,000 0,01517615 0,03388163 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,01517615 0,03386091 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,01517615 0,03384021 ! microspike assembly GO:0030035 15 11 0,000 0,01517615 0,03381954 ! lamellipodium assembly GO:0030032 22 11 0,000 0,01517615 0,0337989 ! fibrillar collagen GO:0005583 12 11 0,000 0,01517615 0,03377827 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,01517615 0,03375768 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,01517615 0,03373711 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,01517615 0,03371656 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,01517615 0,03369604 ! synaptonemal complex GO:0000795 11 11 0,000 0,01517615 0,03367554 ! reproductive cellular process GO:0048610 13 11 0,000 0,01517615 0,03365507 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,01517615 0,03363462 ! positive regulation of B cell proliferation GO:0030890 15 11 0,000 0,01517615 0,0336142 ! Golgi vesicle budding GO:0048194 12 11 0,000 0,01517615 0,0335938 ! response to cAMP GO:0051591 11 11 0,000 0,01517615 0,03357343 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,01517615 0,03355309 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,01517615 0,03353276 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01517615 0,03351246 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,01517615 0,03349219 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,01517615 0,03347194 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,01517615 0,03345172 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 0,01517615 0,03343152 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,01517615 0,03341134 ! drug transport GO:0015893 12 11 0,000 0,01517615 0,03339119 ! FMN binding GO:0010181 12 11 0,000 0,01517615 0,03337106 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,01517615 0,03335096 ! water transporter activity GO:0005372 17 11 0,000 0,01517615 0,03333088 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,01517615 0,03331082 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01517615 0,03329079 ! multicellular organism growth GO:0035264 12 11 0,000 0,01517615 0,03327079 ! integrator complex GO:0032039 11 11 0,000 0,01517615 0,03325081 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,01517615 0,03323085 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,01517615 0,03321091 ! brush border membrane GO:0031526 12 11 0,000 0,01517615 0,033191 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,01517615 0,03317111 ! negative regulation of caspase activity GO:0043154 12 11 0,000 0,01517615 0,03315125 ! macroautophagy GO:0016236 12 11 0,000 0,01517615 0,03313141 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,01517615 0,0331116 ! neuromuscular junction GO:0031594 12 11 0,000 0,01517615 0,03309181 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,01517615 0,03307204 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,01517615 0,03305229 ! response to antibiotic GO:0046677 13 11 0,000 0,01517615 0,03303257 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,01517615 0,03301287 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,01517615 0,0329932 ! proteasome accessory complex GO:0022624 11 11 0,000 0,01517615 0,03297355 ! neuroblast proliferation GO:0007405 13 11 0,000 0,01517615 0,03295392 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,01517615 0,03293432 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,01517615 0,03291474 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,01517615 0,03289518 ! protein kinase C binding GO:0005080 11 11 0,000 0,01517615 0,03287565 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,01517615 0,03285614 ! male genitalia development GO:0030539 15 11 0,000 0,01517615 0,03283665 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,01517615 0,03281718 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,01517615 0,03279774 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,01517615 0,03277832 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,01517615 0,03275893 ! arylsulfatase activity GO:0004065 12 11 0,000 0,01517615 0,03273956 ! sterol transporter activity GO:0015248 11 11 0,000 0,01517615 0,03272021 ! response to nicotine GO:0035094 13 11 0,000 0,01517615 0,03270088 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01517615 0,03268158 ! rRNA transcription GO:0009303 12 12 0,000 0,01654476 0,03560785 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,01654476 0,03558685 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,01654476 0,03556588 ! superoxide anion generation GO:0042554 12 12 0,000 0,01654476 0,03554493 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,01654476 0,03552401 ! regulation of S phase GO:0033261 16 12 0,000 0,01654476 0,03550312 ! regulation of chemokine production GO:0032642 13 12 0,000 0,01654476 0,03548224 ! male meiosis GO:0007140 12 12 0,000 0,01654476 0,0354614 ! signal complex assembly GO:0007172 15 12 0,000 0,01654476 0,03544057 ! positive regulation of GTPase activity GO:0043547 17 12 0,000 0,01654476 0,03541978 ! GTP metabolic process GO:0046039 14 12 0,000 0,01654476 0,035399 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,01654476 0,03537825 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,01654476 0,03535753 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,01654476 0,03533683 GO:0034706|sodium channel complex, ! cartilage condensation GO:0001502 14 12 0,000 0,01654476 0,03531615 ! polysome GO:0005844 14 12 0,000 0,01654476 0,0352955 ! hippocampus development GO:0021766 13 12 0,000 0,01654476 0,03527487 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,01654476 0,03525426 ! beta-amyloid binding GO:0001540 12 12 0,000 0,01654476 0,03523368 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,01654476 0,03521313 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,01654476 0,03519259 ! regulation of exit from mitosis GO:0007096 31 12 0,000 0,01654476 0,03517209 ! chylomicron GO:0042627 13 12 0,000 0,01654476 0,0351516 ! T cell selection GO:0045058 22 12 0,000 0,01654476 0,03513114 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,01654476 0,0351107 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,01654476 0,03509029 ! WW domain binding GO:0050699 12 12 0,000 0,01654476 0,0350699 ! methionine metabolic process GO:0006555 14 12 0,000 0,01654476 0,03504953 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,01654476 0,03502919 ! glycine metabolic process GO:0006544 14 12 0,000 0,01654476 0,03500887 ! plasma membrane organization GO:0007009 12 12 0,000 0,01654476 0,03498858 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01654476 0,03496831 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,01654476 0,03494806 ! Golgi organization GO:0007030 15 12 0,000 0,01654476 0,03492783 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01654476 0,03490763 ! mitotic spindle organization GO:0007052 13 12 0,000 0,01654476 0,03488746 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,01654476 0,0348673 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,01654476 0,03484717 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,01654476 0,03482706 ! temperature homeostasis GO:0001659 13 12 0,000 0,01654476 0,03480698 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,01654476 0,03478692 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01654476 0,03476688 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01654476 0,03474686 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,01654476 0,03472687 ! axon cargo transport GO:0008088 13 12 0,000 0,01654476 0,0347069 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,01654476 0,03468695 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,01654476 0,03466703 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,01654476 0,03464713 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,01654476 0,03462725 ! basal lamina GO:0005605 12 12 0,000 0,01654476 0,0346074 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,01654476 0,03458756 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,01654476 0,03456775 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,01654476 0,03454797 ! biomineral formation GO:0031214 14 12 0,000 0,01654476 0,0345282 ! water homeostasis GO:0030104 12 12 0,000 0,01654476 0,03450846 ! promoter binding GO:0010843 14 12 0,000 0,01654476 0,03448874 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,01654476 0,03446905 ! intestinal absorption GO:0050892 14 12 0,000 0,01654476 0,03444937 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,01654476 0,03442972 ! oocyte differentiation GO:0009994 13 12 0,000 0,01654476 0,03441009 ! oxygen transport GO:0015671 13 12 0,000 0,01654476 0,03439048 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,01654476 0,0343709 ! cholesterol efflux GO:0033344 13 12 0,000 0,01654476 0,03435134 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,01654476 0,0343318 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,01654476 0,03431228 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,01654476 0,03429278 ! tropomyosin binding GO:0005523 12 12 0,000 0,01654476 0,03427331 ! blastocyst formation GO:0001825 13 12 0,000 0,01654476 0,03425386 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,01654476 0,03423443 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,01654476 0,03421502 ! mannose binding GO:0005537 13 12 0,000 0,01654476 0,03419564 ! phosphoprotein binding GO:0051219 14 12 0,000 0,01654476 0,03417627 ! defense response to fungus GO:0050832 12 12 0,000 0,01654476 0,03415693 ! embryonic placenta development GO:0001892 16 12 0,000 0,01654476 0,03413761 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01654476 0,03411831 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,01654476 0,03409904 ! acyl-CoA binding GO:0000062 12 12 0,000 0,01654476 0,03407978 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,01654476 0,03406055 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,01654476 0,03404134 ! copper ion transport GO:0006825 12 12 0,000 0,01654476 0,03402215 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,01654476 0,03400299 ! inositol metabolic process GO:0006020 21 12 0,000 0,01654476 0,03398384 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,01654476 0,03396471 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,01654476 0,03394561 ! protein complex disassembly GO:0043241 15 12 0,000 0,01654476 0,03392653 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,01654476 0,03390747 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,01654476 0,03388843 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,01654476 0,03386942 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,01654476 0,03385042 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,01654476 0,03383145 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,01654476 0,03381249 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,01654476 0,03379356 ! endoderm development GO:0007492 13 12 0,000 0,01654476 0,03377465 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,01654476 0,03375576 ! focal adhesion formation GO:0048041 16 12 0,000 0,01654476 0,03373689 ! T cell receptor complex GO:0042101 31 12 0,000 0,01654476 0,03371804 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,01654476 0,03369922 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,01654476 0,03368041 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,01654476 0,03366163 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,01654476 0,03364286 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,01654476 0,03362412 ! retinol binding GO:0019841 12 12 0,000 0,01654476 0,0336054 ! regulation of organ growth GO:0046620 12 12 0,000 0,01654476 0,0335867 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,01654476 0,03356802 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,01654476 0,03354936 ! histone acetylation GO:0016573 13 12 0,000 0,01654476 0,03353072 ! ribosome binding GO:0043022 13 12 0,000 0,01654476 0,0335121 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,01654476 0,03349351 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,01654476 0,03347493 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,01654476 0,03345637 ! tissue regeneration GO:0042246 12 12 0,000 0,01654476 0,03343784 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,01654476 0,03341932 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,01654476 0,03340083 ! germ cell nucleus GO:0043073 14 12 0,000 0,01654476 0,03338236 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,01654476 0,0333639 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,01654476 0,03334547 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01654476 0,03332706 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01654476 0,03330866 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,01654476 0,03329029 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,01654476 0,03327194 ! dopamine metabolic process GO:0042417 15 12 0,000 0,01654476 0,03325361 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,01654476 0,0332353 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,01654476 0,03321701 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,01654476 0,03319873 ! bacterial binding GO:0008367 14 12 0,000 0,01654476 0,03318048 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01654476 0,03316225 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,01654476 0,03314404 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,01654476 0,03312585 ! localization within membrane GO:0051668 13 12 0,000 0,01654476 0,03310768 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,01654476 0,03308953 ! axoneme part GO:0044447 12 12 0,000 0,01654476 0,0330714 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01791155 0,03578386 ! neuron maturation GO:0042551 14 13 0,000 0,01791155 0,03576428 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01791155 0,03574471 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01791155 0,03572517 ! bone remodeling GO:0046849 14 13 0,000 0,01791155 0,03570565 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01791155 0,03568615 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01791155 0,03566667 ! striated muscle thin filament GO:0005865 14 13 0,000 0,01791155 0,03564721 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01791155 0,03562777 ! organelle fusion GO:0048284 16 13 0,000 0,01791155 0,03560836 ! palate development GO:0060021 15 13 0,000 0,01791155 0,03558896 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01791155 0,03556959 ! arginine metabolic process GO:0006525 14 13 0,000 0,01791155 0,03555024 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01791155 0,03553091 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01791155 0,03551159 ! response to retinoic acid GO:0032526 17 13 0,000 0,01791155 0,03549231 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01791155 0,03547304 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01791155 0,03545379 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01791155 0,03543456 ! fear response GO:0042596 15 13 0,000 0,01791155 0,03541536 ! epithelial cell development GO:0002064 22 13 0,000 0,01791155 0,03539617 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,01791155 0,03537701 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01791155 0,03535786 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01791155 0,03533874 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01791155 0,03531964 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01791155 0,03530056 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01791155 0,0352815 ! cranial nerve development GO:0021545 15 13 0,000 0,01791155 0,03526246 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,01791155 0,03524344 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01791155 0,03522444 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,01791155 0,03520546 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01791155 0,0351865 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01791155 0,03516756 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01791155 0,03514865 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01791155 0,03512975 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01791155 0,03511087 ! NADP metabolic process GO:0006739 15 13 0,000 0,01791155 0,03509202 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01791155 0,03507318 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01791155 0,03505436 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01791155 0,03503557 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01791155 0,03501679 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01791155 0,03499804 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01791155 0,0349793 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01791155 0,03496059 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01791155 0,03494189 ! ADP binding GO:0043531 15 13 0,000 0,01791155 0,03492321 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01791155 0,03490456 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01791155 0,03488592 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01791155 0,03486731 ! neuron fate specification GO:0048665 25 13 0,000 0,01791155 0,03484871 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01791155 0,03483014 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01791155 0,03481158 ! water transport GO:0006833 18 13 0,000 0,01791155 0,03479304 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01791155 0,03477453 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01791155 0,03475603 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01791155 0,03473755 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01791155 0,03471909 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01791155 0,03470066 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,01791155 0,03468224 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01791155 0,03466384 ! myoblast differentiation GO:0045445 15 13 0,000 0,01791155 0,03464546 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01791155 0,0346271 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01791155 0,03460876 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01791155 0,03459044 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01791155 0,03457213 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,01791155 0,03455385 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01791155 0,03453559 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01791155 0,03451735 ! exocrine system development GO:0035272 14 13 0,000 0,01791155 0,03449912 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01791155 0,03448092 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01791155 0,03446273 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01791155 0,03444456 ! L-glutamate transport GO:0015813 14 13 0,000 0,01791155 0,03442641 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01791155 0,03440829 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01791155 0,03439018 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01791155 0,03437209 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01791155 0,03435401 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01791155 0,03433596 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,01791155 0,03431793 ! genitalia development GO:0048806 18 13 0,000 0,01791155 0,03429991 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01791155 0,03428192 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01791155 0,03426394 ! MHC class I protein binding GO:0042288 23 13 0,000 0,01791155 0,03424598 ! histone deacetylation GO:0016575 14 13 0,000 0,01791155 0,03422804 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01791155 0,03421012 ! DNA methylation GO:0006306 15 13 0,000 0,01791155 0,03419222 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01791155 0,03417434 ! chromatin silencing GO:0006342 13 13 0,000 0,01791155 0,03415647 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01791155 0,03413863 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01791155 0,0341208 ! T cell homeostasis GO:0043029 14 13 0,000 0,01791155 0,03410299 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01791155 0,0340852 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01791155 0,03406743 ! response to gamma radiation GO:0010332 14 13 0,000 0,01791155 0,03404968 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01791155 0,03403195 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01791155 0,03401423 ! purine base metabolic process GO:0006144 15 13 0,000 0,01791155 0,03399653 ! cAMP binding GO:0030552 15 13 0,000 0,01791155 0,03397885 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01791155 0,03396119 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01791155 0,03394355 ! regulation of axon extension GO:0030516 16 13 0,000 0,01791155 0,03392593 ! drug transporter activity GO:0015238 14 13 0,000 0,01791155 0,03390832 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01791155 0,03389073 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01791155 0,03387316 ! response to cold GO:0009409 13 13 0,000 0,01791155 0,03385561 ! cadherin binding GO:0045296 16 13 0,000 0,01791155 0,03383808 ! nucleolar part GO:0044452 13 13 0,000 0,01791155 0,03382057 ! tRNA modification GO:0006400 14 14 0,000 0,01927651 0,03637905 ! cis-Golgi network GO:0005801 16 14 0,000 0,01927651 0,03636024 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,01927651 0,03634145 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,01927651 0,03632268 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,01927651 0,03630393 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,01927651 0,03628519 ! peroxisomal transport GO:0043574 14 14 0,000 0,01927651 0,03626648 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,01927651 0,03624779 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,01927651 0,03622911 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,01927651 0,03621046 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,01927651 0,03619182 ! negative regulation of peptidase activity GO:0010466 16 14 0,000 0,01927651 0,0361732 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,01927651 0,03615461 ! positive regulation of cell growth GO:0030307 15 14 0,000 0,01927651 0,03613603 ! caspase activator activity GO:0008656 16 14 0,000 0,01927651 0,03611747 ! MHC class II protein complex GO:0042613 19 14 0,000 0,01927651 0,03609893 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01927651 0,0360804 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,01927651 0,0360619 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,01927651 0,03604342 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,01927651 0,03602495 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01927651 0,03600651 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,01927651 0,03598808 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,01927651 0,03596967 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,01927651 0,03595128 ! response to vitamin A GO:0033189 18 14 0,000 0,01927651 0,03593291 ! actin filament bundle formation GO:0051017 16 14 0,000 0,01927651 0,03591456 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,01927651 0,03589623 ! plasma membrane fusion GO:0045026 15 14 0,000 0,01927651 0,03587791 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,01927651 0,03585962 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,01927651 0,03584134 ! protein export from nucleus GO:0006611 14 14 0,000 0,01927651 0,03582308 ! presynaptic membrane GO:0042734 14 14 0,000 0,01927651 0,03580484 ! negative regulation of immune response GO:0050777 21 14 0,000 0,01927651 0,03578662 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,01927651 0,03576842 ! neural crest cell migration GO:0001755 15 14 0,000 0,01927651 0,03575023 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,01927651 0,03573207 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,01927651 0,03571392 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,01927651 0,03569579 ! cofactor transport GO:0051181 16 14 0,000 0,01927651 0,03567768 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01927651 0,03565959 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,01927651 0,03564151 ! cobalt ion binding GO:0050897 14 14 0,000 0,01927651 0,03562346 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01927651 0,03560542 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,01927651 0,0355874 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,01927651 0,0355694 ! gas transport GO:0015669 15 14 0,000 0,01927651 0,03555142 ! heme biosynthetic process GO:0006783 14 14 0,000 0,01927651 0,03553345 ! release of cytochrome c from mitochondria GO:0001836 26 14 0,000 0,01927651 0,03551551 ! cerebellar cortex development GO:0021695 16 14 0,000 0,01927651 0,03549758 ! insulin secretion GO:0030073 17 14 0,000 0,01927651 0,03547967 ! tRNA binding GO:0000049 16 14 0,000 0,01927651 0,03546178 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,01927651 0,0354439 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,01927651 0,03542605 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,01927651 0,03540821 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,01927651 0,03539039 ! regulation of B cell proliferation GO:0030888 18 14 0,000 0,01927651 0,03537259 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,01927651 0,03535481 ! MAP kinase activity GO:0004707 16 14 0,000 0,01927651 0,03533704 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,01927651 0,03531929 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,01927651 0,03530156 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,01927651 0,03528385 ! C-C chemokine binding GO:0019957 15 14 0,000 0,01927651 0,03526615 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,01927651 0,03524847 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,01927651 0,03523082 ! response to osmotic stress GO:0006970 17 14 0,000 0,01927651 0,03521317 ! fructose metabolic process GO:0006000 15 14 0,000 0,01927651 0,03519555 ! telomeric DNA binding GO:0042162 17 14 0,000 0,01927651 0,03517794 ! monoamine transport GO:0015844 15 14 0,000 0,01927651 0,03516035 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,01927651 0,03514278 ! dendritic spine GO:0043197 15 14 0,000 0,01927651 0,03512523 ! stem cell development GO:0048864 14 14 0,000 0,01927651 0,03510769 GO:0019827|stem cell maintenance, ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,01927651 0,03509017 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,01927651 0,03507267 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,01927651 0,03505519 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01927651 0,03503772 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,01927651 0,03502027 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01927651 0,03500284 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,01927651 0,03498543 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,01927651 0,03496803 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,01927651 0,03495065 ! mannosidase activity GO:0015923 19 14 0,000 0,01927651 0,03493329 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,01927651 0,03491594 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,01927651 0,03489861 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,01927651 0,0348813 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,01927651 0,03486401 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,01927651 0,03484673 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01927651 0,03482947 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,01927651 0,03481223 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,01927651 0,03479501 ! sperm-egg recognition GO:0035036 17 14 0,000 0,01927651 0,0347778 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,01927651 0,03476061 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,01927651 0,03474343 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,01927651 0,03472628 ! positive regulation of translation GO:0045727 17 15 0,000 0,02063965 0,03716359 ! nuclear replication fork GO:0043596 26 15 0,000 0,02063965 0,03714525 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,02063965 0,03712694 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,02063965 0,03710864 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,02063965 0,03709036 ! endothelial cell migration GO:0043542 16 15 0,000 0,02063965 0,0370721 ! lipid phosphorylation GO:0046834 19 15 0,000 0,02063965 0,03705385 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,02063965 0,03703562 ! response to vitamin GO:0033273 19 15 0,000 0,02063965 0,03701742 ! gene silencing by RNA GO:0031047 17 15 0,000 0,02063965 0,03699923 ! striated muscle thick filament GO:0005863 16 15 0,000 0,02063965 0,03698105 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,02063965 0,0369629 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,02063965 0,03694476 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,02063965 0,03692664 ! glutamate metabolic process GO:0006536 17 15 0,000 0,02063965 0,03690854 ! pituitary gland development GO:0021983 16 15 0,000 0,02063965 0,03689046 ! cholesterol binding GO:0015485 15 15 0,000 0,02063965 0,03687239 ! protease binding GO:0002020 20 15 0,000 0,02063965 0,03685434 ! regulation of heart rate GO:0002027 20 15 0,000 0,02063965 0,03683631 ! actin filament bundle GO:0032432 18 15 0,000 0,02063965 0,0368183 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,02063965 0,03680031 ! regulation of exocytosis GO:0017157 16 15 0,000 0,02063965 0,03678233 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,02063965 0,03676437 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,02063965 0,03674643 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,02063965 0,0367285 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,02063965 0,03671059 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,02063965 0,0366927 ! neuron recognition GO:0008038 18 15 0,000 0,02063965 0,03667483 ! regulation of Rho GTPase activity GO:0032319 18 15 0,000 0,02063965 0,03665697 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,02063965 0,03663914 ! filopodium GO:0030175 17 15 0,000 0,02063965 0,03662132 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,02063965 0,03660351 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,02063965 0,03658573 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,02063965 0,03656796 ! peptide hormone binding GO:0017046 16 15 0,000 0,02063965 0,03655021 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,02063965 0,03653247 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,02063965 0,03651476 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,02063965 0,03649706 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,02063965 0,03647937 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,02063965 0,03646171 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,02063965 0,03644406 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,02063965 0,03642643 ! developmental induction GO:0031128 17 15 0,000 0,02063965 0,03640881 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,02063965 0,03639122 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,02063965 0,03637364 ! lactation GO:0007595 17 15 0,000 0,02063965 0,03635607 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,02063965 0,03633853 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02063965 0,036321 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02063965 0,03630348 ! double-strand break repair via homologous recombination GO:0000724 36 15 0,000 0,02063965 0,03628599 GO:0000725|recombinational repair, ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,02063965 0,03626851 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,02063965 0,03625105 ! sulfate transport GO:0008272 16 15 0,000 0,02063965 0,0362336 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,02063965 0,03621617 ! bile acid metabolic process GO:0008206 17 15 0,000 0,02063965 0,03619876 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,02063965 0,03618137 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,02063965 0,03616399 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,02063965 0,03614663 ! heart looping GO:0001947 18 15 0,000 0,02063965 0,03612928 ! protein kinase C activity GO:0004697 17 15 0,000 0,02063965 0,03611195 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,02063965 0,03609464 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,02063965 0,03607735 ! pigmentation during development GO:0048066 17 15 0,000 0,02063965 0,03606007 ! cytokine metabolic process GO:0042107 15 15 0,000 0,02063965 0,03604281 ! vesicle coating GO:0006901 17 15 0,000 0,02063965 0,03602556 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,02063965 0,03600833 ! neutral amino acid transport GO:0015804 18 15 0,000 0,02063965 0,03599112 ! L-amino acid transport GO:0015807 16 15 0,000 0,02063965 0,03597393 ! microfilament motor activity GO:0000146 15 15 0,000 0,02063965 0,03595675 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,02063965 0,03593958 ! regulation of vasodilation GO:0042312 25 15 0,000 0,02063965 0,03592244 ! DNA replication initiation GO:0006270 15 15 0,000 0,02063965 0,03590531 ! taste receptor activity GO:0008527 15 15 0,000 0,02063965 0,03588819 ! cellular pigmentation GO:0033059 16 15 0,000 0,02063965 0,03587109 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,02063965 0,03585401 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,02063965 0,03583695 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,02063965 0,0358199 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,02063965 0,03580287 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,02063965 0,03578585 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,02063965 0,03576885 ! ion gated channel activity GO:0022839 17 15 0,000 0,02063965 0,03575186 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,02063965 0,0357349 ! receptor activator activity GO:0030546 17 15 0,000 0,02063965 0,03571794 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,02063965 0,03570101 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,02063965 0,03568409 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,02063965 0,03566718 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,02063965 0,0356503 ! peptide hormone processing GO:0016486 19 15 0,000 0,02063965 0,03563342 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,02063965 0,03561657 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,02200096 0,03794775 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,02200096 0,03792982 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,02200096 0,0379119 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,02200096 0,037894 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,02200096 0,03787612 ! kinesin complex GO:0005871 16 16 0,000 0,02200096 0,03785825 ! photoreceptor cell development GO:0042461 22 16 0,000 0,02200096 0,0378404 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,02200096 0,03782257 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,02200096 0,03780476 ! centrosome cycle GO:0007098 26 16 0,000 0,02200096 0,03778696 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,02200096 0,03776917 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,02200096 0,03775141 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,02200096 0,03773366 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,02200096 0,03771593 ! lysosomal transport GO:0007041 16 16 0,000 0,02200096 0,03769821 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,02200096 0,03768051 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,02200096 0,03766283 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,02200096 0,03764517 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,02200096 0,03762752 ! myofibril assembly GO:0030239 17 16 0,000 0,02200096 0,03760989 GO:0055002|striated muscle cell development, ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 0,000 0,02200096 0,03759227 ! G1 phase GO:0051318 17 16 0,000 0,02200096 0,03757467 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,02200096 0,03755709 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,02200096 0,03753952 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,02200096 0,03752197 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,02200096 0,03750444 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,02200096 0,03748692 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,02200096 0,03746942 ! steroid catabolic process GO:0006706 18 16 0,000 0,02200096 0,03745194 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,02200096 0,03743447 ! cell-cell recognition GO:0009988 19 16 0,000 0,02200096 0,03741701 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,02200096 0,03739958 ! spleen development GO:0048536 19 16 0,000 0,02200096 0,03738216 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,02200096 0,03736476 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,02200096 0,03734737 ! neural tube closure GO:0001843 19 16 0,000 0,02200096 0,03733 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,02200096 0,03731264 ! regulation of protein ubiquitination GO:0031396 27 16 0,000 0,02200096 0,03729531 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,02200096 0,03727798 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,02200096 0,03726068 ! viral genome replication GO:0019079 16 16 0,000 0,02200096 0,03724339 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,02200096 0,03722611 ! memory GO:0007613 18 16 0,000 0,02200096 0,03720885 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,02200096 0,03719161 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02200096 0,03717438 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,02200096 0,03715717 ! glycoprotein binding GO:0001948 19 16 0,000 0,02200096 0,03713998 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,02200096 0,0371228 ! syntaxin binding GO:0019905 18 16 0,000 0,02200096 0,03710564 ! myosin binding GO:0017022 17 16 0,000 0,02200096 0,03708849 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,02200096 0,03707136 ! fucose metabolic process GO:0006004 18 16 0,000 0,02200096 0,03705425 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,02200096 0,03703715 ! membrane budding GO:0006900 18 16 0,000 0,02200096 0,03702006 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,02200096 0,037003 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,02200096 0,03698594 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,02200096 0,03696891 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,02200096 0,03695189 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,02200096 0,03693488 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,02200096 0,03691789 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,02200096 0,03690092 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,02200096 0,03688396 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,02200096 0,03686702 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,02200096 0,03685009 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,02200096 0,03683318 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,02200096 0,03681628 ! axoneme GO:0005930 16 16 0,000 0,02200096 0,0367994 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,02200096 0,03678254 ! anion exchanger activity GO:0015380 17 17 0,000 0,02336045 0,03903753 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,02336045 0,03901966 ! skin development GO:0043588 20 17 0,000 0,02336045 0,0390018 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,02336045 0,03898396 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,02336045 0,03896613 ! glial cell development GO:0021782 17 17 0,000 0,02336045 0,03894832 ! limbic system development GO:0021761 18 17 0,000 0,02336045 0,03893053 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,02336045 0,03891275 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,02336045 0,03889499 ! ephrin receptor activity GO:0005003 21 17 0,000 0,02336045 0,03887725 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,02336045 0,03885952 ! glutamine metabolic process GO:0006541 26 17 0,000 0,02336045 0,03884181 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,02336045 0,03882411 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,02336045 0,03880643 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,02336045 0,03878877 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,02336045 0,03877112 ! organelle subcompartment GO:0031984 19 17 0,000 0,02336045 0,03875349 ! regulation of dephosphorylation GO:0035303 20 17 0,000 0,02336045 0,03873588 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,02336045 0,03871828 ! membrane depolarization GO:0051899 19 17 0,000 0,02336045 0,0387007 ! oogenesis GO:0048477 20 17 0,000 0,02336045 0,03868313 ! nuclear outer membrane GO:0005640 21 17 0,000 0,02336045 0,03866558 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,02336045 0,03864804 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,02336045 0,03863052 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,02336045 0,03861302 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,02336045 0,03859553 ! organic cation transport GO:0015695 17 17 0,000 0,02336045 0,03857806 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,02336045 0,0385606 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,02336045 0,03854316 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,02336045 0,03852574 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,02336045 0,03850833 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,02336045 0,03849094 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,02336045 0,03847356 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,02336045 0,0384562 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,02336045 0,03843885 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02336045 0,03842152 ! lipid localization GO:0010876 19 17 0,000 0,02336045 0,0384042 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,02336045 0,03838691 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,02336045 0,03836962 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,02336045 0,03835235 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,02336045 0,0383351 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,02336045 0,03831786 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,02336045 0,03830064 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,02336045 0,03828344 ! response to hexose stimulus GO:0009746 20 17 0,000 0,02336045 0,03826625 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,02336045 0,03824907 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,02336045 0,03823191 ! AMP binding GO:0016208 19 17 0,000 0,02336045 0,03821477 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,02336045 0,03819764 ! receptor metabolic process GO:0043112 20 17 0,000 0,02336045 0,03818052 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,02336045 0,03816343 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,02336045 0,03814634 ! alcohol binding GO:0043178 20 17 0,000 0,02336045 0,03812928 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,02336045 0,03811222 ! visual learning GO:0008542 31 17 0,000 0,02336045 0,03809519 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,02336045 0,03807816 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,02336045 0,03806116 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,02336045 0,03804417 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,02336045 0,03802719 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,02336045 0,03801023 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,02336045 0,03799328 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,02336045 0,03797635 ! translation elongation factor activity GO:0003746 19 17 0,000 0,02336045 0,03795943 ! histone binding GO:0042393 26 17 0,000 0,02336045 0,03794253 ! cilium assembly GO:0042384 18 17 0,000 0,02336045 0,03792565 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,02336045 0,03790878 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,02336045 0,03789192 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,02336045 0,03787508 ! protein secretion GO:0009306 19 18 0,000 0,02471813 0,04005852 ! positive regulation of cell size GO:0045793 19 18 0,000 0,02471813 0,04004074 ! positive regulation of ossification GO:0045778 19 18 0,000 0,02471813 0,04002296 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,02471813 0,04000521 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,02471813 0,03998747 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,02471813 0,03996974 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,02471813 0,03995203 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,02471813 0,03993434 ! cAMP metabolic process GO:0046058 18 18 0,000 0,02471813 0,03991666 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,02471813 0,039899 ! cornified envelope GO:0001533 22 18 0,000 0,02471813 0,03988135 ! retinoid metabolic process GO:0001523 19 18 0,000 0,02471813 0,03986372 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,02471813 0,0398461 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,02471813 0,03982851 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,02471813 0,03981092 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,02471813 0,03979335 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,02471813 0,0397758 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,02471813 0,03975826 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,02471813 0,03974074 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,02471813 0,03972323 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,02471813 0,03970574 ! primary neural tube formation GO:0014020 21 18 0,000 0,02471813 0,03968826 ! recycling endosome GO:0055037 22 18 0,000 0,02471813 0,0396708 ! muscle cell development GO:0055001 20 18 0,000 0,02471813 0,03965336 ! kinase activator activity GO:0019209 22 18 0,000 0,02471813 0,03963593 ! cerebellum development GO:0021549 20 18 0,000 0,02471813 0,03961851 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,02471813 0,03960111 ! somitogenesis GO:0001756 20 18 0,000 0,02471813 0,03958373 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,02471813 0,03956636 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,02471813 0,03954901 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,02471813 0,03953167 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,02471813 0,03951435 ! basal plasma membrane GO:0009925 21 18 0,000 0,02471813 0,03949704 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,02471813 0,03947974 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,02471813 0,03946247 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,02471813 0,0394452 ! regulation of cell killing GO:0031341 24 18 0,000 0,02471813 0,03942796 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,02471813 0,03941072 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,02471813 0,03939351 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,02471813 0,0393763 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,02471813 0,03935912 ! protein complex scaffold GO:0032947 22 18 0,000 0,02471813 0,03934194 ! SNAP receptor activity GO:0005484 21 18 0,000 0,02471813 0,03932479 ! dendrite development GO:0016358 22 18 0,000 0,02471813 0,03930764 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,02471813 0,03929052 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,02471813 0,0392734 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,02471813 0,03925631 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,02471813 0,03923922 ! nuclear ubiquitin ligase complex GO:0000152 31 18 0,000 0,02471813 0,03922216 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,02471813 0,0392051 ! coreceptor activity GO:0015026 28 18 0,000 0,02471813 0,03918806 ! response to fungus GO:0009620 18 18 0,000 0,02471813 0,03917104 ! stem cell differentiation GO:0048863 18 18 0,000 0,02471813 0,03915403 ! intermediate filament-based process GO:0045103 18 18 0,000 0,02471813 0,03913704 ! heart process GO:0003015 19 18 0,000 0,02471813 0,03912006 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,02471813 0,03910309 ! vasodilation GO:0042311 20 18 0,000 0,02471813 0,03908614 ! transport vesicle membrane GO:0030658 23 18 0,000 0,02471813 0,03906921 ! MHC protein binding GO:0042287 30 18 0,000 0,02471813 0,03905229 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,02471813 0,03903538 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,02471813 0,03901849 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,02471813 0,03900162 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,02471813 0,03898475 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,02471813 0,03896791 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,02471813 0,03895107 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,02471813 0,03893426 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,02471813 0,03891745 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,02607399 0,04103448 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,02607399 0,04101678 ! proteasome core complex GO:0005839 20 19 0,000 0,02607399 0,0409991 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,02607399 0,04098144 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,02607399 0,04096379 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,02607399 0,04094616 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,02607399 0,04092854 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,02607399 0,04091093 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,02607399 0,04089334 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,02607399 0,04087577 ! lysosome organization GO:0007040 20 19 0,000 0,02607399 0,04085821 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,02607399 0,04084067 ! central nervous system neuron development GO:0021954 21 19 0,000 0,02607399 0,04082314 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,02607399 0,04080563 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,02607399 0,04078813 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,02607399 0,04077065 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,02607399 0,04075318 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,02607399 0,04073573 ! peptide cross-linking GO:0018149 23 19 0,000 0,02607399 0,04071829 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,02607399 0,04070086 ! beta-catenin binding GO:0008013 23 19 0,000 0,02607399 0,04068346 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,02607399 0,04066606 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,02607399 0,04064868 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02607399 0,04063132 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,02607399 0,04061397 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,02607399 0,04059664 ! vitamin transport GO:0051180 21 19 0,000 0,02607399 0,04057932 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,02607399 0,04056201 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,02607399 0,04054472 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,02607399 0,04052745 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,02607399 0,04051019 ! retinoid binding GO:0005501 19 19 0,000 0,02607399 0,04049294 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,02607399 0,04047571 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,02607399 0,04045849 ! histone deacetylase activity GO:0004407 20 19 0,000 0,02607399 0,04044129 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,02607399 0,04042411 ! positive regulation of fibroblast proliferation GO:0048146 25 19 0,000 0,02607399 0,04040693 ! gluconeogenesis GO:0006094 23 19 0,000 0,02607399 0,04038977 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,02607399 0,04037263 ! microtubule-based transport GO:0010970 20 19 0,000 0,02607399 0,0403555 ! superoxide metabolic process GO:0006801 21 19 0,000 0,02607399 0,04033839 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,02607399 0,04032129 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02607399 0,0403042 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,02607399 0,04028713 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,02607399 0,04027008 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,02607399 0,04025303 ! acetylcholine binding GO:0042166 20 19 0,000 0,02607399 0,04023601 ! heme metabolic process GO:0042168 20 19 0,000 0,02607399 0,04021899 ! SH2 domain binding GO:0042169 25 19 0,000 0,02607399 0,04020199 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,02607399 0,04018501 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,02607399 0,04016804 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,02607399 0,04015108 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,02607399 0,04013414 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,02607399 0,04011722 ! body fluid secretion GO:0007589 21 19 0,000 0,02607399 0,0401003 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,02607399 0,0400834 ! secretory granule membrane GO:0030667 21 19 0,000 0,02607399 0,04006652 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,02607399 0,04004965 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,02607399 0,04003279 ! peptidase activator activity GO:0016504 21 19 0,000 0,02607399 0,04001595 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02607399 0,03999913 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,02607399 0,03998231 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,02607399 0,03996551 ! sialyltransferase activity GO:0008373 31 19 0,000 0,02607399 0,03994873 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,02607399 0,03993196 ! chaperone binding GO:0051087 21 20 0,000 0,02742804 0,04198804 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,02742804 0,04197042 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,02742804 0,04195283 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,02742804 0,04193524 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,02742804 0,04191768 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,02742804 0,04190012 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,02742804 0,04188258 ! negative regulation of lipid metabolic process GO:0045833 34 20 0,000 0,02742804 0,04186506 ! ovarian follicle development GO:0001541 21 20 0,000 0,02742804 0,04184755 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 0,000 0,02742804 0,04183006 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,02742804 0,04181257 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,02742804 0,04179511 ! diencephalon development GO:0021536 22 20 0,000 0,02742804 0,04177766 ! nuclear inner membrane GO:0005637 21 20 0,000 0,02742804 0,04176022 ! regulation of lipid transport GO:0032368 22 20 0,000 0,02742804 0,0417428 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,02742804 0,04172539 ! glutathione metabolic process GO:0006749 21 20 0,000 0,02742804 0,041708 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,02742804 0,04169062 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,02742804 0,04167326 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,02742804 0,04165591 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,02742804 0,04163857 ! peptide hormone secretion GO:0030072 25 20 0,000 0,02742804 0,04162125 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,02742804 0,04160395 ! Rab GTPase binding GO:0017137 22 20 0,000 0,02742804 0,04158665 ! initiation of viral infection GO:0019059 22 20 0,000 0,02742804 0,04156938 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,02742804 0,04155211 ! heterochromatin GO:0000792 20 20 0,000 0,02742804 0,04153487 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,02742804 0,04151763 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,02742804 0,04150041 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,02742804 0,04148321 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,02742804 0,04146601 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,02742804 0,04144884 ! visual behavior GO:0007632 34 20 0,000 0,02742804 0,04143167 ! regulation of cell-matrix adhesion GO:0001952 26 20 0,000 0,02742804 0,04141452 GO:0010810|regulation of cell-substrate adhesion, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,02742804 0,04139739 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,02742804 0,04138027 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,02742804 0,04136316 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,02742804 0,04134607 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,02742804 0,04132899 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,02742804 0,04131193 ! rRNA binding GO:0019843 22 20 0,000 0,02742804 0,04129488 ! cytolysis GO:0019835 22 20 0,000 0,02742804 0,04127784 ! renal system process GO:0003014 22 20 0,000 0,02742804 0,04126082 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,02742804 0,04124381 ! fatty acid transport GO:0015908 23 20 0,000 0,02742804 0,04122682 ! transaminase activity GO:0008483 22 20 0,000 0,02742804 0,04120984 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,02742804 0,04119287 ! collagen catabolic process GO:0030574 21 20 0,000 0,02742804 0,04117592 ! microvillus GO:0005902 25 20 0,000 0,02742804 0,04115898 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,02742804 0,04114206 ! connexon complex GO:0005922 23 20 0,000 0,02742804 0,04112515 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,02878028 0,04313495 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,02878028 0,04311723 ! translational initiation GO:0006413 21 21 0,000 0,02878028 0,04309953 ! NF-kappaB binding GO:0051059 31 21 0,000 0,02878028 0,04308185 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,02878028 0,04306418 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,02878028 0,04304652 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,02878028 0,04302888 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,02878028 0,04301125 ! glutathione transferase activity GO:0004364 21 21 0,000 0,02878028 0,04299364 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,02878028 0,04297604 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,02878028 0,04295845 ! regeneration GO:0031099 24 21 0,000 0,02878028 0,04294088 ! apoptotic mitochondrial changes GO:0008637 33 21 0,000 0,02878028 0,04292333 ! MHC class I protein complex GO:0042612 31 21 0,000 0,02878028 0,04290579 ! cellular response to starvation GO:0009267 22 21 0,000 0,02878028 0,04288826 ! peroxisome organization GO:0007031 22 21 0,000 0,02878028 0,04287075 ! vacuole organization GO:0007033 23 21 0,000 0,02878028 0,04285325 ! apoptotic nuclear changes GO:0030262 24 21 0,000 0,02878028 0,04283576 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,02878028 0,0428183 ! neural crest cell development GO:0014032 24 21 0,000 0,02878028 0,04280084 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,02878028 0,0427834 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,02878028 0,04276597 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,02878028 0,04274856 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02878028 0,04273116 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,02878028 0,04271378 ! pallium development GO:0021543 22 21 0,000 0,02878028 0,0426964 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,02878028 0,04267905 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 0,000 0,02878028 0,04266171 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,02878028 0,04264438 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,02878028 0,04262706 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,02878028 0,04260976 ! cyclase activity GO:0009975 22 21 0,000 0,02878028 0,04259248 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,02878028 0,04257521 ! gut development GO:0048565 23 21 0,000 0,02878028 0,04255795 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,02878028 0,0425407 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,02878028 0,04252347 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02878028 0,04250626 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,02878028 0,04248906 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02878028 0,04247187 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,02878028 0,04245469 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,02878028 0,04243753 ! axis specification GO:0009798 25 21 0,000 0,02878028 0,04242039 ! response to alkaloid GO:0043279 27 21 0,000 0,02878028 0,04240326 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,02878028 0,04238614 ! response to ethanol GO:0045471 28 21 0,000 0,02878028 0,04236903 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,02878028 0,04235194 ! smooth muscle contraction GO:0006939 25 21 0,000 0,02878028 0,04233486 ! ubiquitin binding GO:0043130 25 21 0,000 0,02878028 0,0423178 ! vesicle targeting GO:0006903 22 21 0,000 0,02878028 0,04230075 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,02878028 0,04228371 ! SNARE binding GO:0000149 24 21 0,000 0,02878028 0,04226669 ! interaction with host GO:0051701 26 21 0,000 0,02878028 0,04224968 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,02878028 0,04223269 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,02878028 0,04221571 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,02878028 0,04219874 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,02878028 0,04218178 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,02878028 0,04216484 ! cell-cell junction organization GO:0045216 24 21 0,000 0,02878028 0,04214792 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,02878028 0,042131 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,02878028 0,0421141 ! caveola GO:0005901 25 21 0,000 0,02878028 0,04209722 ! insulin receptor binding GO:0005158 25 21 0,000 0,02878028 0,04208034 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02878028 0,04206349 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02878028 0,04204664 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,03013071 0,04400193 ! metencephalon development GO:0022037 25 22 0,000 0,03013071 0,04398433 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,03013071 0,04396673 ! hormone secretion GO:0046879 28 22 0,000 0,03013071 0,04394915 ! vesicle docking GO:0048278 24 22 0,000 0,03013071 0,04393159 ! muscle myosin complex GO:0005859 23 22 0,000 0,03013071 0,04391404 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,03013071 0,0438965 ! actomyosin structure organization GO:0031032 24 22 0,000 0,03013071 0,04387898 ! microtubule organizing center organization GO:0031023 33 22 0,000 0,03013071 0,04386147 GO:0051297|centrosome organization, ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,03013071 0,04384397 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 0,000 0,03013071 0,04382649 ! sperm motility GO:0030317 23 22 0,000 0,03013071 0,04380902 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,03013071 0,04379157 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,03013071 0,04377413 ! vacuolar transport GO:0007034 22 22 0,000 0,03013071 0,0437567 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,03013071 0,04373929 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,03013071 0,04372189 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,03013071 0,04370451 ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,03013071 0,04368714 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,03013071 0,04366978 ! PML body GO:0016605 25 22 0,000 0,03013071 0,04365244 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,03013071 0,04363511 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,03013071 0,04361779 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,03013071 0,04360049 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,03013071 0,0435832 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,03013071 0,04356593 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,03013071 0,04354867 ! deacetylase activity GO:0019213 23 22 0,000 0,03013071 0,04353142 ! pentose metabolic process GO:0019321 23 22 0,000 0,03013071 0,04351419 ! collagen fibril organization GO:0030199 32 22 0,000 0,03013071 0,04349697 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,03013071 0,04347976 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,03013071 0,04346257 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,03013071 0,04344539 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,03013071 0,04342822 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! positive regulation of B cell activation GO:0050871 26 22 0,000 0,03013071 0,04341107 ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,03013071 0,04339393 ! positive regulation of behavior GO:0048520 24 22 0,000 0,03013071 0,04337681 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,03013071 0,0433597 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,03013071 0,0433426 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,03013071 0,04332552 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,03013071 0,04330844 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,03013071 0,04329139 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,03013071 0,04327434 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,03013071 0,04325731 ! glycerol metabolic process GO:0006071 24 22 0,000 0,03013071 0,0432403 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,03013071 0,04322329 ! nuclear chromatin GO:0000790 23 22 0,000 0,03013071 0,0432063 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,03013071 0,04318933 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,03013071 0,04317236 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,03013071 0,04315541 ! sterol binding GO:0032934 24 22 0,000 0,03013071 0,04313847 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,03013071 0,04312155 ! digestive system process GO:0022600 25 22 0,000 0,03013071 0,04310464 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,03013071 0,04308774 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,03013071 0,04307086 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,03013071 0,04305399 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,03013071 0,04303713 ! base-excision repair GO:0006284 33 22 0,000 0,03013071 0,04302029 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,03013071 0,04300346 ! DNA modification GO:0006304 25 22 0,000 0,03013071 0,04298664 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,03013071 0,04296983 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,03013071 0,04295304 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,03013071 0,04293626 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,03013071 0,0429195 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,03013071 0,04290275 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,03013071 0,04288601 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,03013071 0,04286928 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,03013071 0,04285257 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,03147934 0,04475316 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,03147934 0,04473573 ! leukocyte adhesion GO:0007159 26 23 0,000 0,03147934 0,04471831 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,03147934 0,0447009 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,03147934 0,04468351 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,03147934 0,04466613 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,03147934 0,04464876 ! ureteric bud development GO:0001657 24 23 0,000 0,03147934 0,04463141 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,03147934 0,04461407 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,03147934 0,04459675 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,03147934 0,04457943 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,03147934 0,04456213 ! deaminase activity GO:0019239 24 23 0,000 0,03147934 0,04454485 ! sensory perception of pain GO:0019233 26 23 0,000 0,03147934 0,04452758 ! lipid kinase activity GO:0001727 26 23 0,000 0,03147934 0,04451032 ! platelet activation GO:0030168 27 23 0,000 0,03147934 0,04449307 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,03147934 0,04447584 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,03147934 0,04445862 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,03147934 0,04444142 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,03147934 0,04442422 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,03147934 0,04440705 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,03147934 0,04438988 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,03147934 0,04437273 ! cell surface binding GO:0043498 28 23 0,000 0,03147934 0,04435559 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,03147934 0,04433846 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,03147934 0,04432135 ! regulation of glucose import GO:0046324 28 23 0,000 0,03147934 0,04430425 ! alditol metabolic process GO:0019400 25 23 0,000 0,03147934 0,04428717 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,03147934 0,04427009 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,03147934 0,04425303 ! zinc ion transport GO:0006829 26 23 0,000 0,03147934 0,04423599 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,03147934 0,04421895 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,03147934 0,04420193 ! sex determination GO:0007530 25 23 0,000 0,03147934 0,04418492 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,03147934 0,04416793 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,03147934 0,04415095 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,03147934 0,04413398 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,03147934 0,04411703 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,03147934 0,04410008 ! positive regulation of nuclear division GO:0051785 35 23 0,000 0,03147934 0,04408316 GO:0045840|positive regulation of mitosis, ! synaptogenesis GO:0007416 25 23 0,000 0,03147934 0,04406624 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,03147934 0,04404934 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,03147934 0,04403245 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,03147934 0,04401557 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,03147934 0,0439987 ! leukocyte proliferation GO:0070661 26 23 0,000 0,03147934 0,04398185 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,03147934 0,04396501 ! growth cone GO:0030426 27 24 0,000 0,03282616 0,04582848 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,03282616 0,04581095 ! actin filament GO:0005884 26 24 0,000 0,03282616 0,04579343 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,03282616 0,04577593 ! pancreas development GO:0031016 27 24 0,000 0,03282616 0,04575844 ! androgen receptor binding GO:0050681 34 24 0,000 0,03282616 0,04574096 ! calcium channel complex GO:0034704 31 24 0,000 0,03282616 0,04572349 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,03282616 0,04570604 ! negative regulation of cell development GO:0010721 30 24 0,000 0,03282616 0,0456886 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,03282616 0,04567118 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,03282616 0,04565377 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,03282616 0,04563637 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,03282616 0,04561898 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,03282616 0,04560161 ! Rho GTPase binding GO:0017048 36 24 0,000 0,03282616 0,04558425 ! regulation of glucose transport GO:0010827 29 24 0,000 0,03282616 0,04556691 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,03282616 0,04554957 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,03282616 0,04553225 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,03282616 0,04551495 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,03282616 0,04549765 ! protein stabilization GO:0050821 24 24 0,000 0,03282616 0,04548037 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,03282616 0,04546311 ! embryonic pattern specification GO:0009880 29 24 0,000 0,03282616 0,04544585 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,03282616 0,04542861 ! RNA polymerase complex GO:0030880 25 24 0,000 0,03282616 0,04541139 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,03282616 0,04539417 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,03282616 0,04537697 ! small conjugating protein binding GO:0032182 29 24 0,000 0,03282616 0,04535978 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,03282616 0,04534261 ! chemokine binding GO:0019956 26 24 0,000 0,03282616 0,04532545 ! catechol metabolic process GO:0009712 29 24 0,000 0,03282616 0,0453083 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,03282616 0,04529116 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,03282616 0,04527404 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,03282616 0,04525693 ! cell aging GO:0007569 47 24 0,000 0,03282616 0,04523983 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,03282616 0,04522274 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,03282616 0,04520567 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,03282616 0,04518861 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,03282616 0,04517157 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,03282616 0,04515453 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,03282616 0,04513751 ! caspase regulator activity GO:0043028 26 24 0,000 0,03282616 0,04512051 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 0,000 0,03282616 0,04510351 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,03282616 0,04508653 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,03282616 0,04506956 ! selenium binding GO:0008430 24 24 0,000 0,03282616 0,04505261 ! spindle pole GO:0000922 35 24 0,000 0,03282616 0,04503566 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,03282616 0,04501873 ! site of polarized growth GO:0030427 28 25 0,000 0,03417118 0,04684572 ! phenol metabolic process GO:0018958 31 25 0,000 0,03417118 0,04682812 ! regulation of lipid biosynthetic process GO:0046890 35 25 0,000 0,03417118 0,04681054 ! protein amino acid acylation GO:0043543 28 25 0,000 0,03417118 0,04679297 ! aromatase activity GO:0070330 28 25 0,000 0,03417118 0,04677541 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,03417118 0,04675786 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,03417118 0,04674033 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,03417118 0,04672281 ! response to starvation GO:0042594 26 25 0,000 0,03417118 0,04670531 ! dynein complex GO:0030286 28 25 0,000 0,03417118 0,04668781 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,03417118 0,04667034 ! regulation of behavior GO:0050795 27 25 0,000 0,03417118 0,04665287 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,03417118 0,04663542 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,03417118 0,04661797 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,03417118 0,04660055 ! hormone transport GO:0009914 31 25 0,000 0,03417118 0,04658313 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,03417118 0,04656573 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,03417118 0,04654834 ! regulation of coagulation GO:0050818 28 25 0,000 0,03417118 0,04653097 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03417118 0,04651361 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,03417118 0,04649626 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,03417118 0,04647892 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,03417118 0,0464616 ! molting cycle process GO:0022404 28 25 0,000 0,03417118 0,04644429 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,03417118 0,04642699 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,03417118 0,0464097 ! phototransduction GO:0007602 27 25 0,000 0,03417118 0,04639243 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,03417118 0,04637517 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,03417118 0,04635793 ! protein phosphatase binding GO:0019903 27 25 0,000 0,03417118 0,04634069 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,03417118 0,04632347 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,03417118 0,04630626 ! autophagy GO:0006914 28 25 0,000 0,03417118 0,04628907 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,03417118 0,04627189 ! response to ionizing radiation GO:0010212 37 25 0,000 0,03417118 0,04625472 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,03417118 0,04623756 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,0355144 0,04803728 ! positive regulation of cell adhesion GO:0045785 34 26 0,000 0,0355144 0,04801947 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,0355144 0,04800168 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,0355144 0,0479839 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,0355144 0,04796614 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,0355144 0,04794839 ! hair cycle GO:0042633 29 26 0,000 0,0355144 0,04793065 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,0355144 0,04791292 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,0355144 0,04789521 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,0355144 0,04787751 ! early endosome membrane GO:0031901 31 26 0,000 0,0355144 0,04785982 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,0355144 0,04784215 ! iron ion homeostasis GO:0055072 29 26 0,000 0,0355144 0,04782449 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,0355144 0,04780684 ! GABA receptor activity GO:0016917 31 26 0,000 0,0355144 0,04778921 ! PDZ domain binding GO:0030165 28 26 0,000 0,0355144 0,04777159 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,0355144 0,04775398 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,0355144 0,04773638 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,0355144 0,0477188 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,0355144 0,04770123 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,0355144 0,04768367 ! fatty acid binding GO:0005504 28 26 0,000 0,0355144 0,04766613 ! blastocyst development GO:0001824 27 26 0,000 0,0355144 0,0476486 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,0355144 0,04763108 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,0355144 0,04761358 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,0355144 0,04759608 ! regulation of fibroblast proliferation GO:0048145 32 26 0,000 0,0355144 0,04757861 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,0355144 0,04756114 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,0355144 0,04754368 ! iron ion transport GO:0006826 33 26 0,000 0,0355144 0,04752624 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,0355144 0,04750882 ! glucose transport GO:0015758 27 26 0,000 0,0355144 0,0474914 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,0355144 0,047474 ! spinal cord development GO:0021510 30 26 0,000 0,0355144 0,04745661 ! histone deacetylase complex GO:0000118 29 26 0,000 0,0355144 0,04743923 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,0355144 0,04742187 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,0355144 0,04740452 ! RNA helicase activity GO:0003724 46 26 0,000 0,0355144 0,04738718 ! brush border GO:0005903 30 26 0,000 0,0355144 0,04736985 ! gap junction GO:0005921 29 26 0,000 0,0355144 0,04735254 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,0355144 0,04733524 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,03685583 0,04910521 ! RNA export from nucleus GO:0006405 31 27 0,000 0,03685583 0,04908728 ! mRNA catabolic process GO:0006402 31 27 0,000 0,03685583 0,04906937 ! myelination GO:0042552 31 27 0,000 0,03685583 0,04905146 ! trans-Golgi network GO:0005802 31 27 0,000 0,03685583 0,04903358 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,03685583 0,0490157 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,03685583 0,04899784 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,03685583 0,04897999 ! vasculogenesis GO:0001570 32 27 0,000 0,03685583 0,04896215 ! hexose transport GO:0008645 28 27 0,000 0,03685583 0,04894433 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,03685583 0,04892652 ! spindle organization GO:0007051 38 27 0,000 0,03685583 0,04890872 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,03685583 0,04889093 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,03685583 0,04887316 ! cell fate determination GO:0001709 29 27 0,000 0,03685583 0,0488554 ! lipid oxidation GO:0034440 29 27 0,000 0,03685583 0,04883766 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,03685583 0,04881992 ! collagen binding GO:0005518 29 27 0,000 0,03685583 0,0488022 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,03685583 0,04878449 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,03685583 0,0487668 ! liver development GO:0001889 33 27 0,000 0,03685583 0,04874912 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,03685583 0,04873145 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,03685583 0,04871379 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,03685583 0,04869615 ! membrane docking GO:0022406 29 27 0,000 0,03685583 0,04867852 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,03685583 0,0486609 GO:0050908|detection of light stimulus involved in visual perception, ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,03685583 0,04864329 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,03685583 0,0486257 ! phospholipid transport GO:0015914 29 27 0,000 0,03685583 0,04860812 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,03685583 0,04859055 ! aminopeptidase activity GO:0004177 33 27 0,000 0,03685583 0,048573 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,03685583 0,04855546 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,03685583 0,04853793 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,03685583 0,04852041 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,03685583 0,04850291 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,03685583 0,04848542 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,03819546 0,05022965 ! Golgi stack GO:0005795 30 28 0,000 0,03819546 0,05021155 ! male gonad development GO:0008584 32 28 0,000 0,03819546 0,05019346 ! regulation of fatty acid metabolic process GO:0019217 41 28 0,000 0,03819546 0,05017538 ! lipoprotein binding GO:0008034 31 28 0,000 0,03819546 0,05015732 ! mesoderm formation GO:0001707 34 28 0,000 0,03819546 0,05013927 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,03819546 0,05012124 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,03819546 0,05010322 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,03819546 0,05008521 ! cofactor catabolic process GO:0051187 31 28 0,000 0,03819546 0,05006721 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,03819546 0,05004923 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,03819546 0,05003125 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,03819546 0,0500133 ! tissue homeostasis GO:0001894 31 28 0,000 0,03819546 0,04999535 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,03819546 0,04997742 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,03819546 0,0499595 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,03819546 0,04994159 ! sister chromatid segregation GO:0000819 49 28 0,000 0,03819546 0,0499237 ! post-embryonic development GO:0009791 32 28 0,000 0,03819546 0,04990582 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,03819546 0,04988795 ! negative regulation of phosphorylation GO:0042326 30 28 0,000 0,03819546 0,04987009 ! detection of visible light GO:0009584 30 28 0,000 0,03819546 0,04985225 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,03819546 0,04983442 ! receptor regulator activity GO:0030545 31 28 0,000 0,03819546 0,0498166 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,03819546 0,0497988 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,03819546 0,04978101 ! response to heat GO:0009408 33 28 0,000 0,03819546 0,04976323 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,03819546 0,04974546 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,0395333 0,05146948 ! hormone binding GO:0042562 31 29 0,000 0,0395333 0,05145112 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,0395333 0,05143277 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,0395333 0,05141443 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,0395333 0,05139611 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,0395333 0,0513778 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,0395333 0,0513595 ! erythrocyte differentiation GO:0030218 35 29 0,000 0,0395333 0,05134122 ! ceramide metabolic process GO:0006672 29 29 0,000 0,0395333 0,05132295 ! replication fork GO:0005657 42 29 0,000 0,0395333 0,05130469 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,0395333 0,05128645 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,0395333 0,05126821 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,0395333 0,05125 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,0395333 0,05123179 ! regulation of pH GO:0006885 30 29 0,000 0,0395333 0,0512136 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,0395333 0,05119542 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,0395333 0,05117725 ! phospholipase C activity GO:0004629 43 29 0,000 0,0395333 0,05115909 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,0395333 0,05114095 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,0395333 0,05112282 ! sodium channel activity GO:0005272 33 29 0,000 0,0395333 0,05110471 ! sarcoplasm GO:0016528 31 29 0,000 0,0395333 0,05108661 ! detection of light stimulus GO:0009583 31 29 0,000 0,0395333 0,05106852 ! spermatid development GO:0007286 30 29 0,000 0,0395333 0,05105044 ! DNA polymerase activity GO:0034061 34 29 0,000 0,0395333 0,05103237 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,0395333 0,05101432 ! sarcolemma GO:0042383 30 29 0,000 0,0395333 0,05099628 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,0395333 0,05097826 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,0395333 0,05096024 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,0395333 0,05094224 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,04086935 0,05264527 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,04086935 0,05262669 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,04086935 0,05260812 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,04086935 0,05258956 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,04086935 0,05257102 ! scavenger receptor activity GO:0005044 39 30 0,000 0,04086935 0,05255249 ! spliceosome assembly GO:0000245 34 30 0,000 0,04086935 0,05253397 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,04086935 0,05251546 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,04086935 0,05249697 ! metanephros development GO:0001656 31 30 0,000 0,04086935 0,05247849 ! glutamate receptor activity GO:0008066 35 30 0,000 0,04086935 0,05246003 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,04086935 0,05244158 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,04086935 0,05242314 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,04086935 0,05240471 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,04086935 0,0523863 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,04086935 0,0523679 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,04086935 0,05234951 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,04086935 0,05233113 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,04086935 0,05231277 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,04086935 0,05229442 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,04086935 0,05227609 ! protein-lipid complex GO:0032994 41 30 0,000 0,04086935 0,05225776 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,04086935 0,05223945 ! negative regulation of protein modification process GO:0031400 34 30 0,000 0,04086935 0,05222116 ! phosphatase binding GO:0019902 34 30 0,000 0,04086935 0,05220287 ! acute-phase response GO:0006953 44 30 0,000 0,04086935 0,0521846 ! segmentation GO:0035282 37 30 0,000 0,04086935 0,05216634 ! response to toxin GO:0009636 33 30 0,000 0,04086935 0,05214809 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,04086935 0,05212986 ! antigen binding GO:0003823 33 30 0,000 0,04086935 0,05211164 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,04086935 0,05209343 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,04086935 0,05207524 ! ensheathment of neurons GO:0007272 35 30 0,000 0,04086935 0,05205705 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,04086935 0,05203888 ! regulation of microtubule-based process GO:0032886 41 30 0,000 0,04086935 0,05202073 ! vesicle localization GO:0051648 31 30 0,000 0,04086935 0,05200258 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,04220362 0,05368159 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,04220362 0,05366288 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 0,000 0,04220362 0,05364418 GO:0045936|negative regulation of phosphate metabolic process, ! acrosomal vesicle GO:0001669 34 31 0,000 0,04220362 0,0536255 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,04220362 0,05360682 ! protein targeting to membrane GO:0006612 35 31 0,000 0,04220362 0,05358816 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,04220362 0,05356952 ! formation of primary germ layer GO:0001704 37 31 0,000 0,04220362 0,05355089 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,04220362 0,05353227 ! endocytic vesicle GO:0030139 33 31 0,000 0,04220362 0,05351366 ! spermatid differentiation GO:0048515 32 31 0,000 0,04220362 0,05349507 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,04220362 0,05347648 ! neuron fate commitment GO:0048663 44 31 0,000 0,04220362 0,05345792 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,04220362 0,05343936 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,04220362 0,05342082 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,04220362 0,05340229 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,04220362 0,05338377 ! cell junction assembly GO:0034329 36 31 0,000 0,04220362 0,05336527 ! peptide transport GO:0015833 36 31 0,000 0,04220362 0,05334678 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,04220362 0,0533283 ! peripheral nervous system development GO:0007422 35 31 0,000 0,04220362 0,05330983 ! I band GO:0031674 34 31 0,000 0,04220362 0,05329138 ! BMP signaling pathway GO:0030509 33 31 0,000 0,04220362 0,05327294 ! adult locomotory behavior GO:0008344 37 31 0,000 0,04220362 0,05325451 ! gene silencing GO:0016458 33 31 0,000 0,04220362 0,0532361 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,0435361 0,05489792 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,0435361 0,05487895 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,0435361 0,05485999 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,0435361 0,05484105 ! meiosis I GO:0007127 53 32 0,000 0,0435361 0,05482212 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,0435361 0,0548032 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,0435361 0,0547843 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,0435361 0,05476541 ! vesicle coat GO:0030120 39 32 0,000 0,0435361 0,05474653 ! cytokine production GO:0001816 32 32 0,000 0,0435361 0,05472766 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,0435361 0,05470881 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,0435361 0,05468997 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,0435361 0,05467115 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,0435361 0,05465233 ! oxygen binding GO:0019825 33 32 0,000 0,0435361 0,05463353 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,0435361 0,05461475 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,0435361 0,05459597 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,0435361 0,05457721 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,0435361 0,05455846 ! microtubule organizing center part GO:0044450 46 32 0,000 0,0435361 0,05453973 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,04486679 0,05618746 ! DNA helicase activity GO:0003678 55 33 0,000 0,04486679 0,05616818 ! neural tube development GO:0021915 37 33 0,000 0,04486679 0,05614891 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,04486679 0,05612965 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,04486679 0,05611041 ! organelle envelope lumen GO:0031970 46 33 0,000 0,04486679 0,05609118 ! regulation of cellular ketone metabolic process GO:0010565 46 33 0,000 0,04486679 0,05607196 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,04486679 0,05605276 ! NAD or NADH binding GO:0051287 36 33 0,000 0,04486679 0,05603357 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,04486679 0,0560144 ! B cell differentiation GO:0030183 37 33 0,000 0,04486679 0,05599523 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 0,000 0,04486679 0,05597608 ! aerobic respiration GO:0009060 35 33 0,000 0,04486679 0,05595694 ! embryonic organ development GO:0048568 41 33 0,000 0,04486679 0,05593782 ! placenta development GO:0001890 39 33 0,000 0,04486679 0,05591871 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,04486679 0,05589961 ! tissue remodeling GO:0048771 37 33 0,000 0,04486679 0,05588053 ! flagellum GO:0019861 34 33 0,000 0,04486679 0,05586146 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,04486679 0,0558424 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,04486679 0,05582335 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,04486679 0,05580432 ! odontogenesis GO:0042476 39 34 0,000 0,04619571 0,05743761 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,04619571 0,05741804 ! lipid homeostasis GO:0055088 37 34 0,000 0,04619571 0,05739848 ! telencephalon development GO:0021537 36 34 0,000 0,04619571 0,05737894 ! negative regulation of hydrolase activity GO:0051346 36 34 0,000 0,04619571 0,05735941 ! clathrin coat GO:0030118 41 34 0,000 0,04619571 0,05733989 ! cell growth GO:0016049 36 34 0,000 0,04619571 0,05732039 ! regulation of B cell activation GO:0050864 40 34 0,000 0,04619571 0,0573009 ! protein polymerization GO:0051258 38 34 0,000 0,04619571 0,05728142 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,04619571 0,05726196 ! learning GO:0007612 51 34 0,000 0,04619571 0,05724251 ! keratinization GO:0031424 40 34 0,000 0,04619571 0,05722307 ! ovulation cycle process GO:0022602 35 34 0,000 0,04619571 0,05720365 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,04619571 0,05718424 ! steroid hormone receptor binding GO:0035258 44 34 0,000 0,04619571 0,05716484 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,04619571 0,05714546 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,04619571 0,05712609 ! amino acid binding GO:0016597 40 34 0,000 0,04619571 0,05710673 ! regulation of protein stability GO:0031647 35 34 0,000 0,04619571 0,05708738 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,04619571 0,05706805 ! glycogen metabolic process GO:0005977 48 34 0,000 0,04619571 0,05704873 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,04619571 0,05702943 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,04619571 0,05701013 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,04619571 0,05699085 ! protein kinase inhibitor activity GO:0004860 37 34 0,000 0,04619571 0,05697159 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,04752285 0,05858849 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 53 35 0,000 0,04752285 0,0585687 ! response to estrogen stimulus GO:0043627 48 35 0,000 0,04752285 0,05854892 ! inner ear morphogenesis GO:0042472 46 35 0,000 0,04752285 0,05852915 ! MHC protein complex GO:0042611 50 35 0,000 0,04752285 0,0585094 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,04752285 0,05848966 ! vesicle lumen GO:0031983 38 35 0,000 0,04752285 0,05846993 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,04752285 0,05845022 ! mesenchymal cell development GO:0014031 40 35 0,000 0,04752285 0,05843052 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,04752285 0,05841083 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,04752285 0,05839116 ! kinase inhibitor activity GO:0019210 47 35 0,000 0,04752285 0,0583715 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,04752285 0,05835185 ! regulation of proteolysis GO:0030162 37 35 0,000 0,04752285 0,05833222 ! ovulation cycle GO:0042698 37 35 0,000 0,04752285 0,0583126 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,04752285 0,05829299 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,04752285 0,0582734 ! collagen GO:0005581 54 35 0,000 0,04752285 0,05825381 ! glucan metabolic process GO:0044042 49 35 0,000 0,04752285 0,05823425 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,04752285 0,05821469 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,04752285 0,05819515 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,04752285 0,05817562 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,04752285 0,05815611 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,04752285 0,0581366 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,04752285 0,05811711 ! maintenance of protein location GO:0045185 45 35 0,000 0,04752285 0,05809764 ! polyol metabolic process GO:0019751 46 35 0,000 0,04752285 0,05807818 ! androgen receptor signaling pathway GO:0030521 47 35 0,000 0,04752285 0,05805873 ! cytokinesis GO:0000910 38 35 0,000 0,04752285 0,05803929 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,04752285 0,05801986 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,04884821 0,05961803 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,04884821 0,05959809 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,04884821 0,05957816 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,04884821 0,05955825 ! SMAD binding GO:0046332 39 36 0,000 0,04884821 0,05953835 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,04884821 0,05951846 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,04884821 0,05949859 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,04884821 0,05947873 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,04884821 0,05945888 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,04884821 0,05943905 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,04884821 0,05941923 ! nucleus organization GO:0006997 42 36 0,000 0,04884821 0,05939943 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 0,000 0,04884821 0,05937963 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,04884821 0,05935985 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,04884821 0,05934009 ! cellular response to extracellular stimulus GO:0031668 37 36 0,000 0,04884821 0,05932033 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,04884821 0,05930059 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,04884821 0,05928086 ! maintenance of location in cell GO:0051651 38 36 0,000 0,04884821 0,05926115 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,0501718 0,06084665 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,0501718 0,06082643 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,0501718 0,06080622 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,0501718 0,06078603 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,0501718 0,06076585 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,0501718 0,06074568 ! endoribonuclease activity GO:0004521 48 37 0,000 0,0501718 0,06072552 ! hindbrain development GO:0030902 43 37 0,000 0,0501718 0,06070538 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,0501718 0,06068526 ! pigmentation GO:0043473 51 37 0,000 0,0501718 0,06066514 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,0501718 0,06064504 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,0501718 0,06062495 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,0501718 0,06060488 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,0501718 0,06058482 ! sensory perception of taste GO:0050909 37 37 0,000 0,0501718 0,06056477 ! cell junction organization GO:0034330 44 37 0,000 0,0501718 0,06054473 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,0501718 0,06052471 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,0501718 0,0605047 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,0501718 0,06048471 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,0501718 0,06046473 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,0501718 0,06044476 ! coated pit GO:0005905 44 37 0,000 0,0501718 0,0604248 ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,05149362 0,06199628 ! regulation of translational initiation GO:0006446 50 38 0,000 0,05149362 0,06197582 ! negative regulation of binding GO:0051100 44 38 0,000 0,05149362 0,06195538 ! organic ether metabolic process GO:0018904 50 38 0,000 0,05149362 0,06193496 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,05149362 0,06191454 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,05149362 0,06189414 ! hydro-lyase activity GO:0016836 44 38 0,000 0,05149362 0,06187376 ! synapse organization GO:0050808 43 38 0,000 0,05149362 0,06185338 ! viral infectious cycle GO:0019058 40 38 0,000 0,05149362 0,06183302 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,05149362 0,06181268 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,05149362 0,06179234 ! organic anion transport GO:0015711 42 38 0,000 0,05149362 0,06177202 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,05149362 0,06175172 ! monosaccharide binding GO:0048029 41 38 0,000 0,05149362 0,06173142 ! muscle fiber development GO:0048747 42 38 0,000 0,05149362 0,06171114 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,05149362 0,06169088 ! phagocytosis GO:0006909 44 38 0,000 0,05149362 0,06167063 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,05149362 0,06165039 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,05149362 0,06163016 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,05149362 0,06160995 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,05149362 0,06158975 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,05149362 0,06156956 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,05149362 0,06154939 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,05149362 0,06152923 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,05281367 0,06308588 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,05281367 0,06306523 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,05281367 0,06304459 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,05281367 0,06302397 ! T cell differentiation GO:0030217 64 39 0,000 0,05281367 0,06300336 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,05281367 0,06298276 ! cell fate specification GO:0001708 55 39 0,000 0,05281367 0,06296218 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,05281367 0,06294161 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,05281367 0,06292105 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,05281367 0,06290051 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,05281367 0,06287998 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,05281367 0,06285947 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,05281367 0,06283896 ! amine receptor activity GO:0008227 48 39 0,000 0,05281367 0,06281848 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,05281367 0,062798 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,05281367 0,06277754 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,05281367 0,06275709 ! double-strand break repair GO:0006302 70 39 0,000 0,05281367 0,06273665 ! pigment metabolic process GO:0042440 43 39 0,000 0,05281367 0,06271623 ! RNA modification GO:0009451 39 39 0,000 0,05281367 0,06269582 ! damaged DNA binding GO:0003684 51 40 0,000 0,05413195 0,06423987 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,05413195 0,06421898 ! peroxisomal membrane GO:0005778 44 40 0,000 0,05413195 0,0641981 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,05413195 0,06417724 ! positive regulation of cell development GO:0010720 43 40 0,000 0,05413195 0,06415639 ! biopolymer methylation GO:0043414 45 40 0,000 0,05413195 0,06413555 ! neuron migration GO:0001764 43 40 0,000 0,05413195 0,06411473 ! regulation of protein secretion GO:0050708 45 40 0,000 0,05413195 0,06409392 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,05413195 0,06407312 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,05413195 0,06405234 ! positive regulation of defense response GO:0031349 41 40 0,000 0,05413195 0,06403157 ! mammary gland development GO:0030879 47 40 0,000 0,05413195 0,06401081 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,05413195 0,06399007 ! neuropeptide binding GO:0042923 42 40 0,000 0,05413195 0,06396934 ! regulation of tube size GO:0035150 44 40 0,000 0,05413195 0,06394863 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,05413195 0,06392793 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,05413195 0,06390724 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,05413195 0,06388656 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,05413195 0,0638659 ! chromatin remodeling GO:0006338 44 40 0,000 0,05413195 0,06384525 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,05413195 0,06382462 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,05544847 0,06535574 ! Notch signaling pathway GO:0007219 46 41 0,000 0,05544847 0,06533463 ! keratin filament GO:0045095 44 41 0,000 0,05544847 0,06531354 ! induction of apoptosis by intracellular signals GO:0008629 56 41 0,000 0,05544847 0,06529245 ! peptide metabolic process GO:0006518 42 41 0,000 0,05544847 0,06527139 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,05544847 0,06525033 ! late endosome membrane GO:0031902 45 41 0,000 0,05544847 0,06522929 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,05544847 0,06520826 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,05544847 0,06518725 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,05544847 0,06516624 ! lamellipodium GO:0030027 56 41 0,000 0,05544847 0,06514526 ! glycolysis GO:0006096 43 41 0,000 0,05544847 0,06512428 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,05544847 0,06510332 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,05544847 0,06508238 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,05676323 0,06660413 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,05676323 0,06658272 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,05676323 0,06656132 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,05676323 0,06653993 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,05676323 0,06651855 ! nuclear export GO:0051168 46 42 0,000 0,05676323 0,06649719 ! developmental growth GO:0048589 45 42 0,000 0,05676323 0,06647584 ! structural constituent of muscle GO:0008307 46 42 0,000 0,05676323 0,06645451 ! mitochondrial transport GO:0006839 45 42 0,000 0,05676323 0,06643319 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,05676323 0,06641188 ! metal cluster binding GO:0051540 47 42 0,000 0,05676323 0,06639059 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,05676323 0,06636931 ! protein serine/threonine phosphatase activity GO:0004722 45 42 0,000 0,05676323 0,06634805 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,05676323 0,0663268 ! RNA catabolic process GO:0006401 49 43 0,000 0,05807622 0,06783928 ! ear morphogenesis GO:0042471 56 43 0,000 0,05807622 0,06781756 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,05807622 0,06779586 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,05807622 0,06777417 ! positive regulation of growth GO:0045927 47 43 0,000 0,05807622 0,0677525 ! cell recognition GO:0008037 51 43 0,000 0,05807622 0,06773084 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,05807622 0,06770919 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,05807622 0,06768756 ! gliogenesis GO:0042063 46 43 0,000 0,05807622 0,06766594 ! endosome transport GO:0016197 48 43 0,000 0,05807622 0,06764434 ! striated muscle contraction GO:0006941 45 43 0,000 0,05807622 0,06762275 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,05807622 0,06760117 ! antioxidant activity GO:0016209 53 43 0,000 0,05807622 0,06757961 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,05807622 0,06755806 ! activation of caspase activity GO:0006919 60 43 0,000 0,05807622 0,06753652 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,05807622 0,067515 ! histone modification GO:0016570 45 43 0,000 0,05807622 0,06749349 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,05807622 0,067472 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,05938746 0,06897341 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,05938746 0,06895145 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,05938746 0,06892952 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,05938746 0,06890759 ! chemokine activity GO:0008009 48 44 0,000 0,05938746 0,06888568 ! ruffle GO:0001726 50 44 0,000 0,05938746 0,06886379 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,05938746 0,0688419 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,05938746 0,06882003 ! cartilage development GO:0051216 48 44 0,000 0,05938746 0,06879818 ! membrane fusion GO:0006944 52 44 0,000 0,05938746 0,06877634 ! channel regulator activity GO:0016247 54 44 0,000 0,05938746 0,06875451 ! excretion GO:0007588 53 44 0,000 0,05938746 0,0687327 ! male sex differentiation GO:0046661 52 44 0,000 0,05938746 0,0687109 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,05938746 0,06868911 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,05938746 0,06866734 ! amino acid activation GO:0043038 45 44 0,000 0,05938746 0,06864559 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,05938746 0,06862384 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,06069695 0,07011478 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,06069695 0,07009258 ! organellar ribosome GO:0000313 46 45 0,000 0,06069695 0,0700704 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,06069695 0,07004823 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,06069695 0,07002608 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,06069695 0,07000394 ! transport vesicle GO:0030133 53 45 0,000 0,06069695 0,06998182 ! regulation of endocytosis GO:0030100 52 45 0,000 0,06069695 0,06995971 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,06069695 0,06993761 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,06069695 0,06991552 ! nuclear matrix GO:0016363 56 45 0,000 0,06069695 0,06989346 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,06069695 0,0698714 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,06069695 0,06984936 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,06069695 0,06982733 ! coated vesicle membrane GO:0030662 52 45 0,000 0,06069695 0,06980532 ! covalent chromatin modification GO:0016569 47 45 0,000 0,06069695 0,06978332 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,06069695 0,06976133 ! synaptosome GO:0019717 50 45 0,000 0,06069695 0,06973936 ! chemokine receptor binding GO:0042379 50 45 0,000 0,06069695 0,0697174 ! regulation of action potential GO:0001508 56 46 0,000 0,06200468 0,07119706 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,06200468 0,07117466 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,06200468 0,07115227 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,06200468 0,0711299 ! eye morphogenesis GO:0048592 57 46 0,000 0,06200468 0,07110754 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,06200468 0,07108519 ! methylation GO:0032259 51 46 0,000 0,06200468 0,07106286 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,06200468 0,07104054 ! regulation of ion transport GO:0043269 54 46 0,000 0,06200468 0,07101823 ! leukocyte migration GO:0050900 49 46 0,000 0,06200468 0,07099594 ! neuromuscular process GO:0050905 56 46 0,000 0,06200468 0,07097366 ! sulfotransferase activity GO:0008146 54 46 0,000 0,06200468 0,0709514 ! JNK cascade GO:0007254 48 46 0,000 0,06200468 0,07092915 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,06200468 0,07090692 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,06331066 0,07237771 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,06331066 0,07235504 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,06331066 0,07233238 ! microtubule binding GO:0008017 61 47 0,000 0,06331066 0,07230973 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,06331066 0,0722871 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,06331066 0,07226448 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,06331066 0,07224188 ! viral reproductive process GO:0022415 53 47 0,000 0,06331066 0,07221929 ! RNA elongation GO:0006354 52 47 0,000 0,06331066 0,07219671 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,06331066 0,07217415 ! response to insulin stimulus GO:0032868 57 47 0,000 0,06331066 0,0721516 ! axon GO:0030424 53 48 0,000 0,06461489 0,07361497 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,06461489 0,07359198 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,06461489 0,07356902 ! proteasome complex GO:0000502 50 48 0,000 0,06461489 0,07354606 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,06461489 0,07352312 ! protein homooligomerization GO:0051260 63 48 0,000 0,06461489 0,07350019 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,06461489 0,07347728 ! kinetochore GO:0000776 69 48 0,000 0,06461489 0,07345439 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,06461489 0,0734315 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,06461489 0,07340863 ! growth factor receptor binding GO:0070851 58 48 0,000 0,06461489 0,07338578 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,06461489 0,07336294 ! inner ear development GO:0048839 60 48 0,000 0,06461489 0,07334011 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,06461489 0,0733173 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,06461489 0,0732945 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,06461489 0,07327172 ! B cell mediated immunity GO:0019724 53 48 0,000 0,06461489 0,07324895 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,06461489 0,0732262 ! regulation of cell shape GO:0008360 55 48 0,000 0,06461489 0,07320345 ! protein N-terminus binding GO:0047485 57 48 0,000 0,06461489 0,07318073 ! establishment of organelle localization GO:0051656 58 48 0,000 0,06461489 0,07315802 ! cell cortex part GO:0044448 54 48 0,000 0,06461489 0,07313532 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,06591738 0,07458641 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,06591738 0,07456328 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,06591738 0,07454017 ! response to temperature stimulus GO:0009266 57 49 0,000 0,06591738 0,07451707 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,06591738 0,07449399 ! lipid modification GO:0030258 55 49 0,000 0,06591738 0,07447092 ! synaptic vesicle GO:0008021 56 49 0,000 0,06591738 0,07444786 ! regulation of gene expression, epigenetic GO:0040029 64 49 0,000 0,06591738 0,07442482 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,06591738 0,07440179 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,06591738 0,07437878 ! maintenance of location GO:0051235 62 49 0,000 0,06591738 0,07435578 ! regulation of actin filament length GO:0030832 62 49 0,000 0,06591738 0,0743328 ! nuclear periphery GO:0034399 60 49 0,000 0,06591738 0,07430982 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,06591738 0,07428687 ! negative regulation of cytoskeleton organization GO:0051494 73 49 0,000 0,06591738 0,07426393 ! nucleotide-excision repair GO:0006289 53 49 0,000 0,06591738 0,074241 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,06721812 0,07568262 ! DNA damage response, signal transduction GO:0042770 84 50 0,000 0,06721812 0,07565927 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,06721812 0,07563593 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,06721812 0,07561261 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,06721812 0,0755893 ! glucose catabolic process GO:0006007 54 50 0,000 0,06721812 0,07556601 ! aging GO:0007568 92 50 0,000 0,06721812 0,07554273 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,06721812 0,07551946 ! heart morphogenesis GO:0003007 57 50 0,000 0,06721812 0,07549621 ! integrin binding GO:0005178 56 50 0,000 0,06721812 0,07547298 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,06721812 0,07544975 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,06851712 0,07688417 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,06851712 0,07686053 ! regulation of ossification GO:0030278 59 51 0,000 0,06851712 0,0768369 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,06851712 0,07681329 ! positive regulation of organelle organization GO:0010638 69 51 0,000 0,06851712 0,07678969 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,06851712 0,07676611 ! endocrine system development GO:0035270 55 51 0,000 0,06851712 0,07674254 ! germ cell development GO:0007281 56 51 0,000 0,06851712 0,07671898 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,06981438 0,07814755 ! regulation of cellular component size GO:0032535 66 52 0,000 0,06981438 0,07812358 ! carbohydrate transport GO:0008643 57 52 0,000 0,06981438 0,07809962 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,06981438 0,07807568 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,06981438 0,07805175 ! cell maturation GO:0048469 68 52 0,000 0,06981438 0,07802784 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,06981438 0,07800394 ! vesicle organization GO:0016050 59 52 0,000 0,06981438 0,07798005 ! kidney development GO:0001822 55 52 0,000 0,06981438 0,07795618 ! cellular component disassembly GO:0022411 69 52 0,000 0,06981438 0,07793233 ! cell redox homeostasis GO:0045454 57 52 0,000 0,06981438 0,07790849 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,06981438 0,07788467 ! lipid transporter activity GO:0005319 58 52 0,000 0,06981438 0,07786085 ! cytokine receptor activity GO:0004896 54 52 0,000 0,06981438 0,07783706 ! antiporter activity GO:0015297 53 52 0,000 0,06981438 0,07781328 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,0711099 0,07923303 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,0711099 0,07920883 ! keratinocyte differentiation GO:0030216 60 53 0,000 0,0711099 0,07918465 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,0711099 0,07916049 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,0711099 0,07913634 ! viral reproduction GO:0016032 59 53 0,000 0,0711099 0,07911221 ! chloride transport GO:0006821 60 53 0,000 0,0711099 0,07908809 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,0711099 0,07906398 ! regulation of protein catabolic process GO:0042176 56 53 0,000 0,0711099 0,07903989 ! regulation of DNA replication GO:0006275 75 53 0,000 0,0711099 0,07901582 ! DNA catabolic process GO:0006308 57 53 0,000 0,0711099 0,07899176 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,0711099 0,07896771 ! single fertilization GO:0007338 58 53 0,000 0,0711099 0,07894368 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,07240369 0,08035554 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,07240369 0,0803311 ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,07240369 0,08030668 ! coated membrane GO:0048475 65 54 0,000 0,07240369 0,08028227 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,07240369 0,08025787 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,07240369 0,08023349 ! cellular defense response GO:0006968 61 54 0,000 0,07240369 0,08020913 ! gastrulation GO:0007369 62 54 0,000 0,07240369 0,08018478 ! dendrite GO:0030425 60 55 0,000 0,07369575 0,08159092 ! regulation of mitosis GO:0007088 79 55 0,000 0,07369575 0,08156617 GO:0051783|regulation of nuclear division, ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,07369575 0,08154143 ! respiratory chain GO:0070469 57 55 0,000 0,07369575 0,0815167 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,07369575 0,08149199 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,07369575 0,0814673 ! translation initiation factor activity GO:0003743 66 55 0,000 0,07369575 0,08144262 ! steroid hormone receptor signaling pathway GO:0030518 70 55 0,000 0,07369575 0,08141795 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,07498607 0,0828184 ! heat shock protein binding GO:0031072 62 56 0,000 0,07498607 0,08279334 ! late endosome GO:0005770 60 56 0,000 0,07498607 0,08276829 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,07498607 0,08274325 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,07498607 0,08271823 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,07498607 0,08269322 ! ribonuclease activity GO:0004540 67 56 0,000 0,07498607 0,08266823 ! mesoderm development GO:0007498 67 56 0,000 0,07498607 0,08264326 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,07498607 0,0826183 ! antigen processing and presentation GO:0019882 73 56 0,000 0,07498607 0,08259335 ! proton transport GO:0015992 59 56 0,000 0,07498607 0,08256842 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,07627467 0,08396197 ! chromosome segregation GO:0007059 92 57 0,000 0,07627467 0,08393665 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,07627467 0,08391133 ! diacylglycerol binding GO:0019992 65 57 0,000 0,07627467 0,08388604 ! B cell activation GO:0042113 63 57 0,000 0,07627467 0,08386075 ! small ribosomal subunit GO:0015935 58 57 0,000 0,07627467 0,08383549 ! detection of external stimulus GO:0009581 64 57 0,000 0,07627467 0,08381024 ! occluding junction GO:0070160 75 58 0,000 0,07756154 0,08519858 GO:0005923|tight junction, ! epidermal cell differentiation GO:0009913 66 58 0,000 0,07756154 0,08517293 ! hydrogen transport GO:0006818 61 58 0,000 0,07756154 0,0851473 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,07756154 0,08512169 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,07756154 0,08509609 ! response to nutrient GO:0007584 68 58 0,000 0,07756154 0,0850705 ! large ribosomal subunit GO:0015934 64 58 0,000 0,07756154 0,08504493 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,07756154 0,08501938 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,07756154 0,08499384 ! myosin complex GO:0016459 64 58 0,000 0,07756154 0,08496831 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,07884668 0,08635026 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,07884668 0,08632434 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,07884668 0,08629844 ! actin filament organization GO:0007015 65 59 0,000 0,07884668 0,08627256 ! regulation of heart contraction GO:0008016 71 59 0,000 0,07884668 0,08624669 ! hexose catabolic process GO:0019320 64 59 0,000 0,07884668 0,08622083 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,07884668 0,086195 ! response to steroid hormone stimulus GO:0048545 74 59 0,000 0,07884668 0,08616917 ! cell projection assembly GO:0030031 79 59 0,000 0,07884668 0,08614337 ! regulation of cellular response to stress GO:0080135 79 59 0,000 0,07884668 0,08611758 ! appendage morphogenesis GO:0035107 68 59 0,000 0,07884668 0,0860918 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,07884668 0,08606604 ! fertilization GO:0009566 65 59 0,000 0,07884668 0,08604029 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,07884668 0,08601456 ! adult behavior GO:0030534 72 59 0,000 0,07884668 0,08598885 ! organelle localization GO:0051640 70 59 0,000 0,07884668 0,08596315 ! positive regulation of secretion GO:0051047 66 60 0,000 0,08013011 0,08733631 ! molecular adaptor activity GO:0060090 73 60 0,000 0,08013011 0,08731023 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,08013011 0,08728415 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,08013011 0,0872581 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,08013011 0,08723206 ! activation of immune response GO:0002253 72 60 0,000 0,08013011 0,08720604 ! cell cycle checkpoint GO:0000075 91 60 0,000 0,08013011 0,08718003 ! regulation of caspase activity GO:0043281 78 60 0,000 0,08013011 0,08715404 ! appendage development GO:0048736 69 60 0,000 0,08013011 0,08712806 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,08013011 0,0871021 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,08141181 0,08846896 ! ear development GO:0043583 76 61 0,000 0,08141181 0,08844261 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,08141181 0,08841628 ! learning or memory GO:0007611 79 61 0,000 0,08141181 0,08838997 ! Ras GTPase binding GO:0017016 78 61 0,000 0,08141181 0,08836367 ! camera-type eye development GO:0043010 69 61 0,000 0,08141181 0,08833739 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,0826918 0,08969958 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,0826918 0,08967292 ! lysosomal membrane GO:0005765 69 62 0,000 0,0826918 0,08964627 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,0826918 0,08961963 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,0826918 0,08959302 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,0826918 0,08956642 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,0826918 0,08953983 ! chloride channel activity GO:0005254 72 62 0,000 0,0826918 0,08951326 ! cell soma GO:0043025 68 62 0,000 0,0826918 0,08948671 ! microtubule motor activity GO:0003777 94 62 0,000 0,0826918 0,08946017 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 0,000 0,0826918 0,08943365 ! focal adhesion GO:0005925 72 62 0,000 0,0826918 0,08940714 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,0826918 0,08938065 ! negative regulation of cell growth GO:0030308 69 63 0,000 0,08397007 0,09073544 ! FAD binding GO:0050660 71 63 0,000 0,08397007 0,09070857 ! regulation of endopeptidase activity GO:0052548 81 63 0,000 0,08397007 0,09068171 ! urogenital system development GO:0001655 75 63 0,000 0,08397007 0,09065488 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,08397007 0,09062806 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,08397007 0,09060125 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,08397007 0,09057446 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,08397007 0,09054769 ! regulation of immune effector process GO:0002697 81 63 0,000 0,08397007 0,09052093 ! negative regulation of protein kinase activity GO:0006469 78 64 0,000 0,08524663 0,09186993 ! respiratory tube development GO:0030323 92 64 0,000 0,08524663 0,0918428 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,08524663 0,09181568 ! tRNA processing GO:0008033 73 64 0,000 0,08524663 0,09178858 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,08524663 0,0917615 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,08524663 0,09173443 ! adaptive immune response GO:0002250 70 64 0,000 0,08524663 0,09170738 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,08524663 0,09168034 ! neurotransmitter transport GO:0006836 72 64 0,000 0,08524663 0,09165332 ! regulation of actin cytoskeleton organization GO:0032956 93 64 0,000 0,08524663 0,09162632 ! nuclear hormone receptor binding GO:0035257 79 64 0,000 0,08524663 0,09159933 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,08524663 0,09157236 ! negative regulation of cell size GO:0045792 71 65 0,000 0,08652148 0,09291444 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,08652148 0,0928871 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,08652148 0,09285977 ! negative regulation of kinase activity GO:0033673 79 65 0,000 0,08652148 0,09283246 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,08652148 0,09280517 ! activation of MAPK activity GO:0000187 74 65 0,000 0,08652148 0,09277789 ! gonad development GO:0008406 71 65 0,000 0,08652148 0,09275062 ! acetyltransferase activity GO:0016407 73 65 0,000 0,08652148 0,09272338 ! developmental maturation GO:0021700 85 66 0,000 0,08779462 0,09406014 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,08779462 0,09403253 ! tubulin binding GO:0015631 92 66 0,000 0,08779462 0,09400493 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,08779462 0,09397734 ! tube morphogenesis GO:0035239 84 66 0,000 0,08779462 0,09394978 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,08779462 0,09392222 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,08779462 0,09389469 ! regulation of peptidase activity GO:0052547 86 67 0,000 0,08906606 0,09522655 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,08906606 0,09519865 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,08906606 0,09517076 ! response to peptide hormone stimulus GO:0043434 79 67 0,000 0,08906606 0,09514289 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,08906606 0,09511504 ! regulation of actin filament-based process GO:0032970 96 67 0,000 0,08906606 0,09508721 ! chloride ion binding GO:0031404 79 67 0,000 0,08906606 0,09505939 ! humoral immune response GO:0006959 75 67 0,000 0,08906606 0,09503158 ! amine binding GO:0043176 77 67 0,000 0,08906606 0,0950038 ! female pregnancy GO:0007565 78 67 0,000 0,08906606 0,09497602 ! extrinsic to membrane GO:0019898 75 67 0,000 0,08906606 0,09494827 ! anion channel activity GO:0005253 77 67 0,000 0,08906606 0,09492053 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,08906606 0,09489281 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,09033579 0,09621751 ! amine catabolic process GO:0009310 73 68 0,000 0,09033579 0,09618942 ! negative regulation of organelle organization GO:0010639 93 68 0,000 0,09033579 0,09616135 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,09033579 0,0961333 ! cell-substrate junction GO:0030055 78 68 0,000 0,09033579 0,09610527 ! respiratory system development GO:0060541 96 68 0,000 0,09033579 0,09607725 ! mRNA transport GO:0051028 88 69 0,000 0,09160382 0,09739747 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,09160382 0,09736909 ! small GTPase binding GO:0031267 86 69 0,000 0,09160382 0,09734073 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,09160382 0,09731238 ! sarcomere GO:0030017 74 69 0,000 0,09160382 0,09728405 ! exocytosis GO:0006887 76 69 0,000 0,09160382 0,09725574 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,09160382 0,09722744 GO:0060538|skeletal muscle organ development, ! nucleosome assembly GO:0006334 87 69 0,000 0,09160382 0,09719916 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,09160382 0,0971709 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,09160382 0,09714265 ! amine biosynthetic process GO:0009309 78 70 0,000 0,09287015 0,09845693 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,09287015 0,09842832 ! early endosome GO:0005769 104 70 0,000 0,09287015 0,09839974 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,09287015 0,09837117 ! negative regulation of transferase activity GO:0051348 85 70 0,000 0,09287015 0,09834261 ! regulation of lipase activity GO:0060191 78 70 0,000 0,09287015 0,09831407 ! amino acid transport GO:0006865 76 70 0,000 0,09287015 0,09828555 ! chromatin assembly GO:0031497 88 70 0,000 0,09287015 0,09825705 ! hormone receptor binding GO:0051427 85 70 0,000 0,09287015 0,09822856 ! calcium channel activity GO:0005262 86 70 0,000 0,09287015 0,09820009 ! axon guidance GO:0007411 87 70 0,000 0,09287015 0,09817163 ! cell cortex GO:0005938 77 70 0,000 0,09287015 0,09814319 ! nuclear chromosome part GO:0044454 94 70 0,000 0,09287015 0,09811477 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,09413478 0,09942202 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,09413478 0,09939325 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,09413478 0,09936449 ! response to hypoxia GO:0001666 84 72 0,000 0,09539771 0,10066846 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,09539771 0,10063935 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,09539771 0,10061025 ! regulation of lyase activity GO:0051339 85 72 0,000 0,09539771 0,10058117 ! acute inflammatory response GO:0002526 91 72 0,000 0,09539771 0,10055211 ! apical junction complex GO:0043296 90 72 0,000 0,09539771 0,10052307 ! phospholipase activity GO:0004620 99 72 0,000 0,09539771 0,10049404 ! membrane raft GO:0045121 81 72 0,000 0,09539771 0,10046503 ! regulation of neurological system process GO:0031644 91 72 0,000 0,09539771 0,10043603 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,09539771 0,10040706 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,09665896 0,10170518 GO:0051480|cytosolic calcium ion homeostasis, ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,09665896 0,10167586 ! exopeptidase activity GO:0008238 81 73 0,000 0,09665896 0,10164655 ! digestion GO:0007586 81 73 0,000 0,09665896 0,10161725 ! regulation of Rho protein signal transduction GO:0035023 88 73 0,000 0,09665896 0,10158798 ! cell-matrix adhesion GO:0007160 102 74 0,000 0,09791851 0,10288212 ! response to oxygen levels GO:0070482 86 74 0,000 0,09791851 0,1028525 ! potassium channel complex GO:0034705 84 74 0,000 0,09791851 0,10282289 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,09791851 0,1027933 ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,09791851 0,10276373 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,09791851 0,10273417 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,09791851 0,10270463 ! blood coagulation GO:0007596 90 74 0,000 0,09791851 0,10267511 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,09791851 0,10264561 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,09791851 0,10261612 ! phosphoinositide-mediated signaling GO:0048015 92 74 0,000 0,09791851 0,10258665 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,09791851 0,1025572 ! ubiquitin ligase complex GO:0000151 91 74 0,000 0,09791851 0,10252776 ! cell projection part GO:0044463 80 74 0,000 0,09791851 0,10249834 ! meiosis GO:0007126 108 75 0,000 0,09917637 0,10378526 GO:0051327|M phase of meiotic cell cycle, ! regulation of DNA binding GO:0051101 94 75 0,000 0,09917637 0,10375549 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,09917637 0,10372575 ! regulation of cell cycle process GO:0010564 113 75 0,000 0,09917637 0,10369602 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,09917637 0,10366631 ! regulation of blood pressure GO:0008217 82 75 0,000 0,09917637 0,10363661 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,09917637 0,10360693 ! neuropeptide signaling pathway GO:0007218 85 76 0,000 0,10043255 0,10488919 ! negative regulation of growth GO:0045926 85 76 0,000 0,10043255 0,10485917 ! defense response to bacterium GO:0042742 81 76 0,000 0,10043255 0,10482917 ! regulation of lipid metabolic process GO:0019216 98 76 0,000 0,10043255 0,10479918 ! cell leading edge GO:0031252 97 76 0,000 0,10043255 0,10476921 ! meiotic cell cycle GO:0051321 109 76 0,000 0,10043255 0,10473926 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,10043255 0,10470933 ! condensed chromosome GO:0000793 106 76 0,000 0,10043255 0,10467941 ! protein-DNA complex GO:0032993 93 76 0,000 0,10043255 0,10464951 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,10043255 0,10461963 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,10043255 0,10458976 ! cytosolic ribosome GO:0022626 82 76 0,000 0,10043255 0,10455991 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,10043255 0,10453008 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,10168704 0,10580557 ! nucleosome organization GO:0034728 96 77 0,000 0,10168704 0,1057754 ! alcohol catabolic process GO:0046164 84 77 0,000 0,10168704 0,10574525 ! vacuolar membrane GO:0005774 86 77 0,000 0,10168704 0,10571511 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,10168704 0,10568499 ! regulation of Ras GTPase activity GO:0032318 88 77 0,000 0,10168704 0,10565489 ! establishment of RNA localization GO:0051236 97 77 0,000 0,10168704 0,10562481 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! myofibril GO:0030016 82 77 0,000 0,10168704 0,10559474 ! protein oligomerization GO:0051259 93 77 0,000 0,10168704 0,10556469 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,10293985 0,10683487 ! endonuclease activity GO:0004519 111 78 0,000 0,10293985 0,10680449 ! inorganic anion transport GO:0015698 87 78 0,000 0,10293985 0,10677412 ! regulation of protein transport GO:0051223 85 78 0,000 0,10293985 0,10674377 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,10293985 0,10671343 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,10293985 0,10668312 ! carboxylesterase activity GO:0004091 93 78 0,000 0,10293985 0,10665282 ! protein ubiquitination GO:0016567 95 78 0,000 0,10293985 0,10662254 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,10293985 0,10659227 ! contractile fiber part GO:0044449 83 78 0,000 0,10293985 0,10656203 ! RNA localization GO:0006403 99 79 0,000 0,10419098 0,10782658 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,10419098 0,107796 ! T cell activation GO:0042110 120 79 0,000 0,10419098 0,10776544 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,10419098 0,10773489 ! phosphoinositide binding GO:0035091 99 79 0,000 0,10419098 0,10770436 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,10544043 0,10896507 ! eye development GO:0001654 93 80 0,000 0,10544043 0,10893421 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,10544043 0,10890337 ! rhythmic process GO:0048511 90 80 0,000 0,10544043 0,10887254 ! regulation of catabolic process GO:0009894 87 80 0,000 0,10544043 0,10884174 ! SH3 domain binding GO:0017124 95 80 0,000 0,10544043 0,10881095 ! hemostasis GO:0007599 96 80 0,000 0,10544043 0,10878018 ! chromosome, centromeric region GO:0000775 119 80 0,000 0,10544043 0,10874942 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,10544043 0,10871868 ! cell-substrate adhesion GO:0031589 109 80 0,000 0,10544043 0,10868796 ! rRNA processing GO:0006364 84 80 0,000 0,10544043 0,10865726 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,10668821 0,10991206 ! vacuolar part GO:0044437 91 81 0,000 0,10668821 0,10988102 ! mitochondrion organization GO:0007005 104 82 0,000 0,10793431 0,11113304 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,10793431 0,11110168 ! external side of plasma membrane GO:0009897 105 82 0,000 0,10793431 0,11107034 ! cellular respiration GO:0045333 85 82 0,000 0,10793431 0,11103902 ! microtubule-based movement GO:0007018 119 83 0,000 0,10917874 0,11228758 ! nuclear speck GO:0016607 99 83 0,000 0,10917874 0,11225593 ! rRNA metabolic process GO:0016072 88 83 0,000 0,10917874 0,1122243 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,10917874 0,11219269 GO:0070035|purine NTP-dependent helicase activity, ! regulation of cell adhesion GO:0030155 98 83 0,000 0,10917874 0,1121611 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,10917874 0,11212952 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,10917874 0,11209796 ! contractile fiber GO:0043292 88 83 0,000 0,10917874 0,11206642 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,10917874 0,1120349 ! regulation of membrane potential GO:0042391 98 83 0,000 0,10917874 0,11200339 ! cilium GO:0005929 88 83 0,000 0,10917874 0,1119719 ! regulation of defense response GO:0031347 98 84 0,000 0,1104215 0,11321463 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,1104215 0,11318282 ! DNA recombination GO:0006310 147 84 0,000 0,1104215 0,11315103 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,1116626 0,11439067 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,1116626 0,11435855 ! monooxygenase activity GO:0004497 92 85 0,000 0,1116626 0,11432646 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,1116626 0,11429438 ! protein binding, bridging GO:0030674 104 85 0,000 0,1116626 0,11426232 ! negative regulation of transport GO:0051051 98 86 0,000 0,11290203 0,11549821 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,11290203 0,11546583 ! Golgi vesicle transport GO:0048193 98 86 0,000 0,11290203 0,11543346 ! lipase activity GO:0016298 114 86 0,000 0,11290203 0,11540112 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,11290203 0,1153688 ! adherens junction GO:0005912 100 86 0,000 0,11290203 0,11533649 ! microtubule cytoskeleton organization GO:0000226 113 87 0,000 0,1141398 0,1165683 ! leukocyte differentiation GO:0002521 118 87 0,000 0,1141398 0,11653568 ! pigment granule GO:0048770 101 87 0,000 0,1141398 0,11650307 GO:0042470|melanosome, ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,1141398 0,11647048 ! organelle outer membrane GO:0031968 102 88 0,000 0,1153759 0,11769891 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,1153759 0,117666 ! protein processing GO:0016485 100 88 0,000 0,1153759 0,11763312 ! protein tyrosine phosphatase activity GO:0004725 109 89 0,000 0,11661035 0,1188585 ! gland development GO:0048732 108 89 0,000 0,11661035 0,11882529 ! ATP metabolic process GO:0046034 100 90 0,000 0,11784314 0,12004797 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,11784314 0,12001445 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,11784314 0,11998096 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,11784314 0,11994748 ! sterol metabolic process GO:0016125 102 90 0,000 0,11784314 0,11991402 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,11784314 0,11988058 ! amine transport GO:0015837 97 90 0,000 0,11784314 0,11984716 ! response to virus GO:0009615 109 90 0,000 0,11784314 0,11981376 ! outer membrane GO:0019867 104 90 0,000 0,11784314 0,11978038 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,11907428 0,12099804 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,11907428 0,12096435 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,11907428 0,12093067 ! sulfur metabolic process GO:0006790 98 91 0,000 0,11907428 0,12089701 ! sex differentiation GO:0007548 103 91 0,000 0,11907428 0,12086337 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 0,000 0,11907428 0,12082975 ! hormone metabolic process GO:0042445 107 91 0,000 0,11907428 0,12079615 ! regulation of protein localization GO:0032880 99 91 0,000 0,11907428 0,12076257 ! detection of stimulus GO:0051606 100 91 0,000 0,11907428 0,12072901 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,12030376 0,12194169 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,12030376 0,12190781 ! regulation of cellular component biogenesis GO:0044087 115 92 0,000 0,12030376 0,12187396 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,12030376 0,12184012 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,12030376 0,12180631 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,12030376 0,12177251 ! regulation of GTPase activity GO:0043087 105 92 0,000 0,12030376 0,12173873 ! cell cycle arrest GO:0007050 103 93 0,000 0,1215316 0,12294711 ! regulation of cytoskeleton organization GO:0051493 133 93 0,000 0,1215316 0,12291302 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,1215316 0,12287895 ! response to nutrient levels GO:0031667 105 93 0,000 0,1215316 0,12284491 ! Ras protein signal transduction GO:0007265 118 93 0,000 0,1215316 0,12281088 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,1215316 0,12277687 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,12275778 0,12398128 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,12275778 0,12394697 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,12275778 0,12391267 GO:0060429|epithelium development, ! anchoring junction GO:0070161 108 94 0,000 0,12275778 0,12387839 ! neurotransmitter binding GO:0042165 105 94 0,000 0,12275778 0,12384414 ! DNA packaging GO:0006323 113 94 0,000 0,12275778 0,1238099 ! homophilic cell adhesion GO:0007156 107 95 0,000 0,12398232 0,12501037 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,12398232 0,12497583 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,12398232 0,1249413 ! Wnt receptor signaling pathway GO:0016055 121 95 0,000 0,12398232 0,1249068 ! immune effector process GO:0002252 110 95 0,000 0,12398232 0,12487231 ! apical plasma membrane GO:0016324 105 95 0,000 0,12398232 0,12483785 ! translational elongation GO:0006414 104 96 0,000 0,12520522 0,1260344 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,12520522 0,12599963 ! in utero embryonic development GO:0001701 110 96 0,000 0,12520522 0,12596488 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,12520522 0,12593015 ! receptor complex GO:0043235 131 96 0,000 0,12520522 0,12589544 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,12520522 0,12586075 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,12520522 0,12582607 ! electron transport chain GO:0022900 104 97 0,000 0,12642648 0,12701839 ! microtubule associated complex GO:0005875 135 97 0,000 0,12642648 0,12698342 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,12642648 0,12694847 ! perinuclear region of cytoplasm GO:0048471 125 97 0,000 0,12642648 0,12691354 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,12642648 0,12687862 ! carboxylic acid binding GO:0031406 108 97 0,000 0,12642648 0,12684373 ! protein maturation GO:0051604 109 97 0,000 0,12642648 0,12680885 ! intermediate filament GO:0005882 102 98 0,000 0,12764609 0,12799696 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,12764609 0,12796179 ! cell fate commitment GO:0045165 118 98 0,000 0,12764609 0,12792663 ! negative regulation of cellular component organization GO:0051129 132 99 0,000 0,12886407 0,12911182 ! hormone activity GO:0005179 113 99 0,000 0,12886407 0,12907637 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,12886407 0,12904094 ! unfolded protein binding GO:0051082 118 100 0,000 0,13008042 0,1302232 ! nuclear chromosome GO:0000228 127 100 0,000 0,13008042 0,13018748 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,13008042 0,13015177 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 0,000 0,13008042 0,13011608 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,13008042 0,13008042