pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/3308-4-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 2,000 1,837E-07 3,386E-04 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 2,000 9,853E-07 9,079E-04 ! muscle cell migration GO:0014812 5 5 1,000 8,861E-06 5,444E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 1,329E-05 6,121E-03 ! positive regulation of cell growth GO:0030307 6 6 1,000 1,329E-05 4,897E-03 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 1,329E-05 4,081E-03 ! thymus development GO:0048538 6 6 1,000 1,329E-05 3,498E-03 ! keratinocyte proliferation GO:0043616 7 7 1,000 1,859E-05 4,283E-03 ! axis specification GO:0009798 7 7 1,000 1,859E-05 3,807E-03 ! induction of an organ GO:0001759 7 7 1,000 1,859E-05 3,426E-03 ! thyroid gland development GO:0030878 8 8 1,000 2,478E-05 4,151E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 2,478E-05 3,805E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 2,478E-05 3,512E-03 ! developmental induction GO:0031128 8 8 1,000 2,478E-05 3,262E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 2,478E-05 3,044E-03 ! positive regulation of cell size GO:0045793 9 9 1,000 3,184E-05 3,667E-03 ! negative regulation of caspase activity GO:0043154 9 9 1,000 3,184E-05 3,452E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 3,184E-05 3,26E-03 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 3,184E-05 3,088E-03 ! negative regulation of signal transduction GO:0009968 71 71 2,000 3,579E-05 3,298E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 3,978E-05 3,491E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 3,978E-05 3,332E-03 ! negative regulation of cell communication GO:0010648 76 76 2,000 4,393E-05 3,52E-03 ! skin development GO:0043588 11 11 1,000 4,86E-05 3,732E-03 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 5,829E-05 4,297E-03 ! ureteric bud development GO:0001657 13 13 1,000 6,885E-05 4,881E-03 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 6,885E-05 4,7E-03 ! activation of JUN kinase activity GO:0007257 13 13 1,000 6,885E-05 4,532E-03 ! pattern specification process GO:0007389 96 94 2,000 8,31E-05 5,281E-03 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 9,259E-05 5,688E-03 ! inner ear morphogenesis GO:0042472 16 16 1,000 1,058E-04 6,288E-03 ! cell fate specification GO:0001708 16 16 1,000 1,058E-04 6,092E-03 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 1,058E-04 5,907E-03 GO:0043507|positive regulation of JUN kinase activity, ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 1,198E-04 6,495E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 1,347E-04 7,094E-03 ! negative regulation of DNA binding GO:0043392 19 18 1,000 1,347E-04 6,897E-03 ! metanephros development GO:0001656 19 19 1,000 1,505E-04 7,497E-03 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 1,505E-04 7,299E-03 ! negative regulation of binding GO:0051100 21 20 1,000 1,671E-04 7,899E-03 ! ear morphogenesis GO:0042471 21 21 1,000 1,847E-04 8,508E-03 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 1,847E-04 8,3E-03 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 1,847E-04 8,103E-03 ! negative regulation of protein transport GO:0051224 21 21 1,000 1,847E-04 7,914E-03 ! embryonic skeletal system development GO:0048706 22 22 1,000 2,03E-04 8,504E-03 ! maintenance of protein location in cell GO:0032507 23 22 1,000 2,03E-04 8,315E-03 ! epithelial cell differentiation GO:0030855 23 23 1,000 2,222E-04 8,904E-03 ! endocrine system development GO:0035270 23 23 1,000 2,222E-04 8,715E-03 ! positive regulation of growth GO:0045927 23 23 1,000 2,222E-04 8,533E-03 ! regulation of JNK cascade GO:0046328 25 23 1,000 2,222E-04 8,359E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 2,423E-04 8,932E-03 ! maintenance of protein location GO:0045185 25 24 1,000 2,423E-04 8,757E-03 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 2,423E-04 8,589E-03 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 2,633E-04 9,155E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 2,851E-04 9,73E-03 ! maintenance of location in cell GO:0051651 27 26 1,000 2,851E-04 9,553E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 3,077E-04 0,01012777 ! inner ear development GO:0048839 27 27 1,000 3,077E-04 9,95E-03 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 3,312E-04 0,01052562 GO:0007254|JNK cascade, ! keratinocyte differentiation GO:0030216 28 28 1,000 3,312E-04 0,01034722 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 3,556E-04 0,01092315 ! skeletal system morphogenesis GO:0048705 31 30 1,000 3,808E-04 0,01150593 ! skeletal muscle fiber development GO:0048741 31 31 1,000 4,069E-04 0,01209519 ! regulation of intracellular transport GO:0032386 31 31 1,000 4,069E-04 0,0119032 ! epidermal cell differentiation GO:0009913 31 31 1,000 4,069E-04 0,01171722 ! muscle fiber development GO:0048747 32 32 1,000 4,338E-04 0,01230011 ! maintenance of location GO:0051235 33 32 1,000 4,338E-04 0,01211374 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 4,338E-04 0,01193294 ! kidney development GO:0001822 32 32 1,000 4,338E-04 0,01175746 ! regulation of cellular response to stress GO:0080135 35 33 1,000 4,616E-04 0,01232863 ! regulation of neuron differentiation GO:0045664 34 33 1,000 4,616E-04 0,0121525 ! ear development GO:0043583 34 34 1,000 4,902E-04 0,012724 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 5,196E-04 0,01330125 ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 5,811E-04 0,01467026 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 5,811E-04 0,01447201 ! urogenital system development GO:0001655 38 38 1,000 6,131E-04 0,01506502 ! negative regulation of kinase activity GO:0033673 38 38 1,000 6,131E-04 0,01486679 ! activation of MAPK activity GO:0000187 39 39 1,000 6,459E-04 0,01545938 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 6,459E-04 0,01526118 ! negative regulation of transferase activity GO:0051348 40 40 1,000 6,796E-04 0,01585336 ! regulation of caspase activity GO:0043281 41 41 1,000 7,141E-04 0,01645003 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 7,494E-04 0,01705101 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 7,494E-04 0,01684307 ! mitochondrion organization GO:0007005 44 43 1,000 7,856E-04 0,01744338 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 8,226E-04 0,0180477 ! regulation of DNA binding GO:0051101 47 45 1,000 8,604E-04 0,01865586 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 8,604E-04 0,01843893 ! tube morphogenesis GO:0035239 47 46 1,000 8,991E-04 0,01904624 ! regulation of peptidase activity GO:0052547 46 46 1,000 8,991E-04 0,0188298 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 8,991E-04 0,01861823 ! positive regulation of ligase activity GO:0051351 47 46 1,000 8,991E-04 0,01841136 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 9,789E-04 0,01982594 ! gland development GO:0048732 51 49 1,000 1,02E-03 0,020435 ! skeletal muscle tissue development GO:0007519 50 49 1,000 1,02E-03 0,02021527 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 1,02E-03 0,02000021 ! regulation of ligase activity GO:0051340 50 49 1,000 1,02E-03 0,01978969 ! negative regulation of transport GO:0051051 51 50 1,000 1,062E-03 0,02038961 ! regulation of neurogenesis GO:0050767 51 50 1,000 1,062E-03 0,02017941 ! cell fate commitment GO:0045165 52 52 1,000 1,149E-03 0,0215993 ! regulation of protein transport GO:0051223 53 53 1,000 1,193E-03 0,0222088 GO:0070201|regulation of establishment of protein localization, ! regulation of nervous system development GO:0051960 57 56 1,000 1,331E-03 0,02453571 ! regulation of binding GO:0051098 60 57 1,000 1,379E-03 0,02516392 ! regulation of protein localization GO:0032880 58 57 1,000 1,379E-03 0,02491722 ! regulation of cell development GO:0060284 60 59 1,000 1,477E-03 0,02642758 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 1,578E-03 0,02796664 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 1,578E-03 0,02770029 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 1,63E-03 0,02833981 GO:0060429|epithelium development, ! regulation of MAP kinase activity GO:0043405 67 66 1,000 1,845E-03 0,03178413 ! striated muscle tissue development GO:0014706 69 67 1,000 1,901E-03 0,03244297 ! Ras protein signal transduction GO:0007265 69 67 1,000 1,901E-03 0,03214533 ! regulation of cell size GO:0008361 68 68 1,000 1,958E-03 0,03280239 ! sensory perception of sound GO:0007605 71 69 1,000 2,015E-03 0,03346095 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 2,015E-03 0,03316219 ! muscle tissue development GO:0060537 72 70 1,000 2,074E-03 0,03381899 ! sensory organ development GO:0007423 72 72 1,000 2,192E-03 0,03544505 ! regulation of protein modification process GO:0031399 79 78 1,000 2,568E-03 0,04116134 ! MAPKKK cascade GO:0000165 82 81 1,000 2,767E-03 0,04396278 ! tube development GO:0035295 83 81 1,000 2,767E-03 0,04358703 ! regulation of cellular localization GO:0060341 86 85 1,000 3,043E-03 0,04752684 ! positive regulation of protein kinase activity GO:0045860 89 86 1,000 3,114E-03 0,04822606 ! positive regulation of transferase activity GO:0051347 91 88 1,000 3,258E-03 0,05003908 GO:0033674|positive regulation of kinase activity, ! DNA replication GO:0006260 91 91 1,000 3,48E-03 0,05300941 ! tissue morphogenesis GO:0048729 94 93 1,000 3,632E-03 0,05487095 ! regulation of response to stress GO:0080134 97 94 1,000 3,709E-03 0,05558093 ! epidermis development GO:0008544 94 94 1,000 3,709E-03 0,0551327 ! regulation of cell growth GO:0001558 97 96 1,000 3,866E-03 0,05700094 ! anti-apoptosis GO:0006916 100 99 1,000 4,107E-03 0,06006943 ! ectoderm development GO:0007398 99 99 1,000 4,107E-03 0,05959644 ! muscle organ development GO:0007517 102 100 1,000 4,189E-03 0,06030822 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 4,189E-03 0,05984071 ! rRNA transcription GO:0009303 5 5 0,000 5,078E-03 0,07199526 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 5,078E-03 0,07144567 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 5,078E-03 0,07090442 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 5,078E-03 0,0703713 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 5,078E-03 0,06984614 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 5,078E-03 0,06932876 ! reproductive cellular process GO:0048610 5 5 0,000 5,078E-03 0,06881899 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 5,078E-03 0,06831667 ! negative regulation of blood pressure GO:0045776 6 5 0,000 5,078E-03 0,06782162 ! prostate gland development GO:0030850 5 5 0,000 5,078E-03 0,06733369 ! metencephalon development GO:0022037 5 5 0,000 5,078E-03 0,06685274 ! water transport GO:0006833 5 5 0,000 5,078E-03 0,0663786 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 5,078E-03 0,06591115 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 5,078E-03 0,06545023 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 5,078E-03 0,06499572 ! glycerol metabolic process GO:0006071 5 5 0,000 5,078E-03 0,06454747 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 5,078E-03 0,06410536 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 5,078E-03 0,06366927 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 5,078E-03 0,06323908 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 5,078E-03 0,06281465 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 5,078E-03 0,06239589 ! filopodium assembly GO:0046847 7 5 0,000 5,078E-03 0,06198267 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 5,078E-03 0,06157489 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 5,078E-03 0,06117244 ! GTP metabolic process GO:0046039 5 5 0,000 5,078E-03 0,06077522 ! establishment of tissue polarity GO:0007164 5 5 0,000 5,078E-03 0,06038312 ! mRNA stabilization GO:0048255 5 5 0,000 5,078E-03 0,05999605 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 5,078E-03 0,05961391 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 5,078E-03 0,0592366 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 5,078E-03 0,05886405 ! social behavior GO:0035176 5 5 0,000 5,078E-03 0,05849615 ! macrophage chemotaxis GO:0048246 6 5 0,000 5,078E-03 0,05813282 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 5,078E-03 0,05777397 ! memory GO:0007613 5 5 0,000 5,078E-03 0,05741953 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 5,078E-03 0,05706941 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 5,078E-03 0,05672353 ! membrane hyperpolarization GO:0060081 5 5 0,000 5,078E-03 0,05638183 ! response to lipid GO:0033993 5 5 0,000 5,078E-03 0,05604421 ! erythrocyte maturation GO:0043249 5 5 0,000 5,078E-03 0,05571061 ! hippocampus development GO:0021766 6 5 0,000 5,078E-03 0,05538097 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 5,078E-03 0,0550552 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 5,078E-03 0,05473324 ! middle ear morphogenesis GO:0042474 5 5 0,000 5,078E-03 0,05441502 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 5,078E-03 0,05410048 ! mechanosensory behavior GO:0007638 5 5 0,000 5,078E-03 0,05378956 ! heart looping GO:0001947 5 5 0,000 5,078E-03 0,05348219 ! negative regulation of endocytosis GO:0045806 5 5 0,000 5,078E-03 0,05317831 ! response to interferon-gamma GO:0034341 5 5 0,000 5,078E-03 0,05287787 ! pseudouridine synthesis GO:0001522 5 5 0,000 5,078E-03 0,0525808 ! endocrine pancreas development GO:0031018 5 5 0,000 5,078E-03 0,05228706 ! pH reduction GO:0045851 5 5 0,000 5,078E-03 0,05199657 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 5,078E-03 0,0517093 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 5,078E-03 0,05142518 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 5,078E-03 0,05114417 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 5,078E-03 0,05086621 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 5,078E-03 0,05059126 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 5,078E-03 0,05031926 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 5,078E-03 0,05005018 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 5,078E-03 0,04978395 ! adrenal gland development GO:0030325 5 5 0,000 5,078E-03 0,04952055 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 5,078E-03 0,04925991 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 5,078E-03 0,04900201 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 5,078E-03 0,04874679 ! astrocyte differentiation GO:0048708 5 5 0,000 5,078E-03 0,04849421 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 5,078E-03 0,04824424 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 5,078E-03 0,04799684 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 5,078E-03 0,04775196 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 5,078E-03 0,04750956 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 5,078E-03 0,04726961 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 5,078E-03 0,04703208 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 5,078E-03 0,04679692 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 5,078E-03 0,0465641 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 5,078E-03 0,04633358 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 5,078E-03 0,04610534 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! phasic smooth muscle contraction GO:0014821 5 5 0,000 5,078E-03 0,04587933 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 5,078E-03 0,04565553 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 5,078E-03 0,0454339 ! response to ATP GO:0033198 5 5 0,000 5,078E-03 0,04521441 ! regulation of type I interferon production GO:0032479 5 5 0,000 5,078E-03 0,04499703 ! regulation of appetite GO:0032098 5 5 0,000 5,078E-03 0,04478174 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 5,078E-03 0,04456849 ! paraxial mesoderm development GO:0048339 5 5 0,000 5,078E-03 0,04435727 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 5,078E-03 0,04414803 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 5,078E-03 0,04394077 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 5,078E-03 0,04373544 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,078E-03 0,04353202 ! receptor clustering GO:0043113 5 5 0,000 5,078E-03 0,04333048 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 5,078E-03 0,0431308 ! fear response GO:0042596 5 5 0,000 5,078E-03 0,04293295 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 5,078E-03 0,04273691 ! lens development in camera-type eye GO:0002088 5 5 0,000 5,078E-03 0,04254265 ! retinol metabolic process GO:0042572 5 5 0,000 5,078E-03 0,04235015 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 5,078E-03 0,04215938 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 5,078E-03 0,04197033 ! positive regulation of exocytosis GO:0045921 6 5 0,000 5,078E-03 0,04178296 ! parturition GO:0007567 5 5 0,000 5,078E-03 0,04159726 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,078E-03 0,0414132 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 5,078E-03 0,04123076 ! Schwann cell differentiation GO:0014037 5 5 0,000 5,078E-03 0,04104993 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 5,078E-03 0,04087067 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 5,078E-03 0,04069297 ! protein heterooligomerization GO:0051291 5 5 0,000 5,078E-03 0,04051681 ! regulation of gliogenesis GO:0014013 5 5 0,000 5,078E-03 0,04034217 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 5,078E-03 0,04016903 ! response to UV-B GO:0010224 5 5 0,000 5,078E-03 0,03999736 ! oligodendrocyte development GO:0014003 5 5 0,000 5,078E-03 0,03982716 ! hyaluronan metabolic process GO:0030212 5 5 0,000 5,078E-03 0,0396584 ! activated T cell proliferation GO:0050798 5 5 0,000 5,078E-03 0,03949107 ! interaction with symbiont GO:0051702 5 5 0,000 5,078E-03 0,03932514 ! cellular extravasation GO:0045123 5 5 0,000 5,078E-03 0,0391606 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 5,078E-03 0,03899743 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 5,078E-03 0,03883562 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 5,078E-03 0,03867514 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 5,078E-03 0,03851598 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 5,078E-03 0,03835813 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 5,078E-03 0,03820156 ! response to amine stimulus GO:0014075 5 5 0,000 5,078E-03 0,03804627 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 5,078E-03 0,03789224 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 5,078E-03 0,03773945 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 5,078E-03 0,03758788 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 5,078E-03 0,03743753 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 5,078E-03 0,03728838 ! neuron recognition GO:0008038 5 5 0,000 5,078E-03 0,03714041 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 5,078E-03 0,03699361 ! decidualization GO:0046697 5 5 0,000 5,078E-03 0,03684797 ! hair follicle maturation GO:0048820 5 5 0,000 5,078E-03 0,03670346 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 5,078E-03 0,03656009 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 5,078E-03 0,03641783 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,078E-03 0,03627668 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 5,078E-03 0,03613661 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 5,078E-03 0,03599763 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 5,078E-03 0,03585971 ! postreplication repair GO:0006301 5 5 0,000 5,078E-03 0,03572284 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 5,078E-03 0,03558701 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 5,078E-03 0,03545221 ! histone methylation GO:0016571 5 5 0,000 5,078E-03 0,03531843 ! DNA methylation GO:0006306 5 5 0,000 5,078E-03 0,03518565 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 5,078E-03 0,03505387 ! T cell lineage commitment GO:0002360 5 5 0,000 5,078E-03 0,03492307 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 5,078E-03 0,03479325 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 5,078E-03 0,03466438 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 5,078E-03 0,03453647 ! intracellular cholesterol transport GO:0032367 5 5 0,000 5,078E-03 0,0344095 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 5,078E-03 0,03428346 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 5,078E-03 0,03415833 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 5,078E-03 0,03403412 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 5,078E-03 0,03391081 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 5,078E-03 0,03378839 ! sterol catabolic process GO:0016127 5 5 0,000 5,078E-03 0,03366685 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 5,078E-03 0,03354618 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 5,078E-03 0,03342637 ! detection of biotic stimulus GO:0009595 5 5 0,000 5,078E-03 0,03330741 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 5,078E-03 0,0331893 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 5,078E-03 0,03307203 ! zymogen activation GO:0031638 5 5 0,000 5,078E-03 0,03295557 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 5,078E-03 0,03283994 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 5,078E-03 0,03272512 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 5,078E-03 0,03261109 ! peptidyl-lysine modification GO:0018205 5 5 0,000 5,078E-03 0,03249786 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 5,078E-03 0,03238541 ! peptidyl-histidine modification GO:0018202 5 5 0,000 5,078E-03 0,03227374 ! nucleosome positioning GO:0016584 5 5 0,000 5,078E-03 0,03216283 ! regulation of isotype switching GO:0045191 5 5 0,000 5,078E-03 0,03205268 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 5,078E-03 0,03194329 ! negative regulation of neurological system process GO:0031645 5 5 0,000 5,078E-03 0,03183464 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 5,078E-03 0,03172672 ! glutathione biosynthetic process GO:0006750 5 5 0,000 5,078E-03 0,03161954 ! NADPH regeneration GO:0006740 5 5 0,000 5,078E-03 0,03151307 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 5,078E-03 0,03140733 ! positive regulation of epidermis development GO:0045684 5 5 0,000 5,078E-03 0,03130229 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 5,078E-03 0,03119794 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 5,078E-03 0,0310943 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 5,078E-03 0,03099134 ! sarcomere organization GO:0045214 5 5 0,000 5,078E-03 0,03088905 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 5,078E-03 0,03078744 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 5,078E-03 0,0306865 ! negative regulation of glucose transport GO:0010829 5 5 0,000 5,078E-03 0,03058622 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 5,078E-03 0,03048659 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 5,078E-03 0,03038761 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 5,078E-03 0,03028927 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 5,078E-03 0,03019156 ! spleen development GO:0048536 5 5 0,000 5,078E-03 0,03009448 ! male genitalia development GO:0030539 5 5 0,000 5,078E-03 0,02999802 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 5,078E-03 0,02990218 ! quaternary ammonium group transport GO:0015697 5 5 0,000 5,078E-03 0,02980695 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 5,078E-03 0,02971233 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 5,078E-03 0,0296183 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 5,078E-03 0,02952487 ! removal of superoxide radicals GO:0019430 6 5 0,000 5,078E-03 0,02943202 ! myeloid cell homeostasis GO:0002262 5 5 0,000 5,078E-03 0,02933976 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 5,078E-03 0,02924807 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 5,078E-03 0,02915696 ! ATP catabolic process GO:0006200 5 5 0,000 5,078E-03 0,02906641 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 5,078E-03 0,02897642 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 5,078E-03 0,02888699 ! blastocyst formation GO:0001825 5 5 0,000 5,078E-03 0,0287981 ! regulation of fibrinolysis GO:0051917 5 5 0,000 5,078E-03 0,02870976 ! embryonic gut development GO:0048566 5 5 0,000 5,078E-03 0,02862197 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 5,078E-03 0,02853471 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 5,078E-03 0,02844797 ! activation of innate immune response GO:0002218 5 5 0,000 5,078E-03 0,02836177 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 5,078E-03 0,02827608 ! catecholamine transport GO:0051937 5 5 0,000 5,078E-03 0,02819091 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 5,078E-03 0,02810626 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 5,078E-03 0,02802211 ! muscle adaptation GO:0043500 5 5 0,000 5,078E-03 0,02793846 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 5,078E-03 0,02785531 ! embryonic heart tube development GO:0035050 5 5 0,000 5,078E-03 0,02777265 ! cardiac cell differentiation GO:0035051 6 5 0,000 5,078E-03 0,02769048 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 5,078E-03 0,0276088 ! defense response to fungus GO:0050832 5 5 0,000 5,078E-03 0,0275276 ! lysogeny GO:0030069 5 5 0,000 5,078E-03 0,02744687 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 5,078E-03 0,02736662 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 5,078E-03 0,02728683 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 5,078E-03 0,02720751 ! response to nicotine GO:0035094 5 5 0,000 5,078E-03 0,02712865 ! establishment of cell polarity GO:0030010 5 5 0,000 5,078E-03 0,02705024 ! mitochondrion localization GO:0051646 5 5 0,000 5,078E-03 0,02697229 ! nucleus localization GO:0051647 5 5 0,000 5,078E-03 0,02689478 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 5,078E-03 0,02681772 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 6,091E-03 0,03207532 ! axon extension GO:0048675 7 6 0,000 6,091E-03 0,03198394 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 6,091E-03 0,03189308 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 6,091E-03 0,03180273 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 6,091E-03 0,03171289 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 6,091E-03 0,03162356 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 6,091E-03 0,03153473 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 6,091E-03 0,03144639 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 6,091E-03 0,03135856 ! virus-host interaction GO:0019048 6 6 0,000 6,091E-03 0,03127121 ! regulation of S phase GO:0033261 6 6 0,000 6,091E-03 0,03118434 ! myotube differentiation GO:0014902 6 6 0,000 6,091E-03 0,03109796 ! regulation of B cell proliferation GO:0030888 6 6 0,000 6,091E-03 0,03101205 ! bone remodeling GO:0046849 6 6 0,000 6,091E-03 0,03092662 ! N-glycan processing GO:0006491 6 6 0,000 6,091E-03 0,03084166 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,091E-03 0,03075716 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 6,091E-03 0,03067312 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 6,091E-03 0,03058954 ! retina development in camera-type eye GO:0060041 6 6 0,000 6,091E-03 0,03050642 ! RNA methylation GO:0001510 6 6 0,000 6,091E-03 0,03042375 ! cartilage condensation GO:0001502 7 6 0,000 6,091E-03 0,03034152 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 6,091E-03 0,03025974 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 6,091E-03 0,03017839 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 6,091E-03 0,03009749 ! artery development GO:0060840 6 6 0,000 6,091E-03 0,03001701 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 6,091E-03 0,02993697 ! bile acid metabolic process GO:0008206 6 6 0,000 6,091E-03 0,02985735 ! androgen metabolic process GO:0008209 6 6 0,000 6,091E-03 0,02977815 ! estrogen metabolic process GO:0008210 6 6 0,000 6,091E-03 0,02969937 ! limbic system development GO:0021761 7 6 0,000 6,091E-03 0,02962101 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 6,091E-03 0,02954306 ! positive regulation of heart contraction GO:0045823 6 6 0,000 6,091E-03 0,02946552 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 6,091E-03 0,02938838 ! pathogenesis GO:0009405 6 6 0,000 6,091E-03 0,02931165 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 6,091E-03 0,02923532 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 6,091E-03 0,02915938 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 6,091E-03 0,02908384 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 6,091E-03 0,02900869 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 6,091E-03 0,02893392 ! arginine metabolic process GO:0006525 6 6 0,000 6,091E-03 0,02885954 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 6,091E-03 0,02878555 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 6,091E-03 0,02871193 ! glutamate catabolic process GO:0006538 7 6 0,000 6,091E-03 0,02863868 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 6,091E-03 0,02856581 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 6,091E-03 0,02849331 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 6,091E-03 0,02842117 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 6,091E-03 0,0283494 ! ER overload response GO:0006983 6 6 0,000 6,091E-03 0,02827799 ! V(D)J recombination GO:0033151 6 6 0,000 6,091E-03 0,02820694 ! focal adhesion formation GO:0048041 7 6 0,000 6,091E-03 0,02813625 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,091E-03 0,02806591 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 6,091E-03 0,02799592 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 6,091E-03 0,02792628 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 6,091E-03 0,02785698 ! regulation of heart rate GO:0002027 6 6 0,000 6,091E-03 0,02778803 ! lipid digestion GO:0044241 6 6 0,000 6,091E-03 0,02771941 ! asymmetric protein localization GO:0008105 6 6 0,000 6,091E-03 0,02765114 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 6,091E-03 0,0275832 ! phagocytosis, engulfment GO:0006911 6 6 0,000 6,091E-03 0,0275156 ! Rac protein signal transduction GO:0016601 6 6 0,000 6,091E-03 0,02744832 ! regulation of vascular permeability GO:0043114 6 6 0,000 6,091E-03 0,02738137 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 6,091E-03 0,02731475 ! ruffle organization GO:0031529 6 6 0,000 6,091E-03 0,02724845 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 6,091E-03 0,02718248 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 6,091E-03 0,02711682 ! retinoic acid metabolic process GO:0042573 6 6 0,000 6,091E-03 0,02705148 ! neutral amino acid transport GO:0015804 6 6 0,000 6,091E-03 0,02698645 ! L-amino acid transport GO:0015807 6 6 0,000 6,091E-03 0,02692173 ! bone mineralization GO:0030282 6 6 0,000 6,091E-03 0,02685733 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 6,091E-03 0,02679323 ! negative regulation of ossification GO:0030279 6 6 0,000 6,091E-03 0,02672944 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 6,091E-03 0,02666594 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 6,091E-03 0,02660276 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 6,091E-03 0,02653986 ! purine base biosynthetic process GO:0009113 6 6 0,000 6,091E-03 0,02647727 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 6,091E-03 0,02641497 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 6,091E-03 0,02635296 ! regulation of phagocytosis GO:0050764 6 6 0,000 6,091E-03 0,02629125 ! regulation of organ growth GO:0046620 6 6 0,000 6,091E-03 0,02622982 ! regulation of circadian rhythm GO:0042752 6 6 0,000 6,091E-03 0,02616868 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 6,091E-03 0,02610782 ! response to dsRNA GO:0043331 6 6 0,000 6,091E-03 0,02604725 ! DNA unwinding during replication GO:0006268 6 6 0,000 6,091E-03 0,02598695 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 6,091E-03 0,02592693 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 6,091E-03 0,0258672 ! genitalia development GO:0048806 6 6 0,000 6,091E-03 0,02580773 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 6,091E-03 0,02574854 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 6,091E-03 0,02568962 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 6,091E-03 0,02563097 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 6,091E-03 0,02557258 ! multicellular organismal aging GO:0010259 6 6 0,000 6,091E-03 0,02551446 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 6,091E-03 0,0254566 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 6,091E-03 0,02539901 ! erythrocyte development GO:0048821 6 6 0,000 6,091E-03 0,02534168 ! renal water homeostasis GO:0003091 6 6 0,000 6,091E-03 0,0252846 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 6,091E-03 0,02522778 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 6,091E-03 0,02517122 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 6,091E-03 0,02511491 ! ribosome assembly GO:0042255 6 6 0,000 6,091E-03 0,02505885 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 6,091E-03 0,02500304 ! diencephalon development GO:0021536 6 6 0,000 6,091E-03 0,02494747 ! fucose catabolic process GO:0019317 6 6 0,000 6,091E-03 0,02489216 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 6,091E-03 0,02483709 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 6,091E-03 0,02478226 ! regulation of lipid transport GO:0032368 6 6 0,000 6,091E-03 0,02472767 ! regulation of cell division GO:0051302 6 6 0,000 6,091E-03 0,02467332 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 6,091E-03 0,02461922 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 6,091E-03 0,02456535 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 6,091E-03 0,02451171 ! salivary gland morphogenesis GO:0007435 6 6 0,000 6,091E-03 0,02445831 ! neuroblast proliferation GO:0007405 6 6 0,000 6,091E-03 0,02440514 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 6,091E-03 0,0243522 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 6,091E-03 0,02429949 ! regulation of glucose transport GO:0010827 6 6 0,000 6,091E-03 0,024247 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 6,091E-03 0,02419475 ! methionine biosynthetic process GO:0009086 6 6 0,000 6,091E-03 0,02414272 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 6,091E-03 0,02409091 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 6,091E-03 0,02403932 ! lymph node development GO:0048535 6 6 0,000 6,091E-03 0,02398795 ! organic cation transport GO:0015695 6 6 0,000 6,091E-03 0,02393681 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 6,091E-03 0,02388588 ! regulation of RNA splicing GO:0043484 6 6 0,000 6,091E-03 0,02383517 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 6,091E-03 0,02378467 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 6,091E-03 0,02373438 ! sperm-egg recognition GO:0035036 7 6 0,000 6,091E-03 0,02368431 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 6,091E-03 0,02363445 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 6,091E-03 0,0235848 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 6,091E-03 0,02353535 ! alditol metabolic process GO:0019400 6 6 0,000 6,091E-03 0,02348611 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 6,091E-03 0,02343708 ! regulation of amino acid transport GO:0051955 6 6 0,000 6,091E-03 0,02338826 ! maternal placenta development GO:0001893 6 6 0,000 6,091E-03 0,02333963 ! regulation of embryonic development GO:0045995 6 6 0,000 6,091E-03 0,02329121 ! negative regulation of immune effector process GO:0002698 6 6 0,000 6,091E-03 0,02324299 ! localization within membrane GO:0051668 6 6 0,000 6,091E-03 0,02319496 ! respiratory burst GO:0045730 7 7 0,000 7,103E-03 0,02699322 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 7,103E-03 0,02693768 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 7,103E-03 0,02688237 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 7,103E-03 0,02682728 ! positive regulation of blood pressure GO:0045777 7 7 0,000 7,103E-03 0,02677242 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 7,103E-03 0,02671778 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 7,103E-03 0,02666337 ! regulation of chemokine production GO:0032642 7 7 0,000 7,103E-03 0,02660917 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 7,103E-03 0,0265552 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 7,103E-03 0,02650144 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 7,103E-03 0,0264479 ! cellular protein complex disassembly GO:0043624 8 7 0,000 7,103E-03 0,02639458 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 7,103E-03 0,02634147 ! gene silencing by RNA GO:0031047 7 7 0,000 7,103E-03 0,02628858 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 7,103E-03 0,0262359 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 7,103E-03 0,02618343 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 7,103E-03 0,02613116 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 7,103E-03 0,02607911 ! visual behavior GO:0007632 7 7 0,000 7,103E-03 0,02602726 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 7,103E-03 0,02597562 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 7,103E-03 0,02592418 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 7,103E-03 0,02587295 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 7,103E-03 0,02582192 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 7,103E-03 0,02577109 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 7,103E-03 0,02572046 ! endothelial cell differentiation GO:0045446 7 7 0,000 7,103E-03 0,02567002 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 7,103E-03 0,02561979 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 7,103E-03 0,02556975 ! digestive system development GO:0055123 7 7 0,000 7,103E-03 0,02551991 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 7,103E-03 0,02547026 ! regulation of exit from mitosis GO:0007096 7 7 0,000 7,103E-03 0,0254208 ! protein targeting to ER GO:0045047 8 7 0,000 7,103E-03 0,02537154 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 7,103E-03 0,02532246 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 7,103E-03 0,02527358 ! endoderm development GO:0007492 7 7 0,000 7,103E-03 0,02522488 ! regulation of defense response to virus GO:0050688 7 7 0,000 7,103E-03 0,02517637 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 7,103E-03 0,02512805 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 7,103E-03 0,02507991 ! response to hexose stimulus GO:0009746 7 7 0,000 7,103E-03 0,02503196 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 7,103E-03 0,02498418 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 7,103E-03 0,0249366 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 7,103E-03 0,02488919 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 7,103E-03 0,02484196 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 7,103E-03 0,02479491 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 7,103E-03 0,02474804 ! complement activation, alternative pathway GO:0006957 7 7 0,000 7,103E-03 0,02470134 ! arachidonic acid secretion GO:0050482 7 7 0,000 7,103E-03 0,02465483 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 7,103E-03 0,02460848 ! response to X-ray GO:0010165 7 7 0,000 7,103E-03 0,02456231 ! regulation of intracellular pH GO:0051453 7 7 0,000 7,103E-03 0,02451632 ! UV protection GO:0009650 7 7 0,000 7,103E-03 0,02447049 ! DNA integration GO:0015074 7 7 0,000 7,103E-03 0,02442484 ! myofibril assembly GO:0030239 7 7 0,000 7,103E-03 0,02437935 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 7,103E-03 0,02433404 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 7,103E-03 0,02428889 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 7,103E-03 0,02424391 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 7,103E-03 0,0241991 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 7,103E-03 0,02415445 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 7,103E-03 0,02410997 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 7,103E-03 0,02406565 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 7,103E-03 0,02402149 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 7,103E-03 0,0239775 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 7,103E-03 0,02393366 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 7,103E-03 0,02388999 ! axon cargo transport GO:0008088 7 7 0,000 7,103E-03 0,02384647 ! eating behavior GO:0042755 7 7 0,000 7,103E-03 0,02380311 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 7,103E-03 0,02375991 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 7,103E-03 0,02371687 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 7,103E-03 0,02367398 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 7,103E-03 0,02363125 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 7,103E-03 0,02358867 ! cranial nerve development GO:0021545 7 7 0,000 7,103E-03 0,02354625 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 7,103E-03 0,02350397 ! leukocyte activation during immune response GO:0002366 7 7 0,000 7,103E-03 0,02346185 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 7,103E-03 0,02341988 ! autonomic nervous system development GO:0048483 7 7 0,000 7,103E-03 0,02337806 ! intracellular lipid transport GO:0032365 7 7 0,000 7,103E-03 0,02333639 ! detection of chemical stimulus GO:0009593 8 7 0,000 7,103E-03 0,02329486 ! platelet activation GO:0030168 8 7 0,000 7,103E-03 0,02325349 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 7,103E-03 0,02321226 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 7,103E-03 0,02317117 ! natural killer cell activation GO:0030101 7 7 0,000 7,103E-03 0,02313023 ! response to gamma radiation GO:0010332 8 7 0,000 7,103E-03 0,02308944 ! NADP metabolic process GO:0006739 7 7 0,000 7,103E-03 0,02304879 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 7,103E-03 0,02300828 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 7,103E-03 0,02296792 ! ubiquinone metabolic process GO:0006743 7 7 0,000 7,103E-03 0,02292769 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 7,103E-03 0,02288761 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 7,103E-03 0,02284767 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 7,103E-03 0,02280786 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 7,103E-03 0,0227682 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 7,103E-03 0,02272867 ! regulation of ATPase activity GO:0043462 7 7 0,000 7,103E-03 0,02268928 ! cell-cell recognition GO:0009988 8 7 0,000 7,103E-03 0,02265002 ! hormone catabolic process GO:0042447 7 7 0,000 7,103E-03 0,0226109 ! dopamine metabolic process GO:0042417 7 7 0,000 7,103E-03 0,02257192 ! cAMP biosynthetic process GO:0006171 7 7 0,000 7,103E-03 0,02253307 ! oxygen transport GO:0015671 7 7 0,000 7,103E-03 0,02249435 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 7,103E-03 0,02245577 ! regulation of mRNA stability GO:0043488 7 7 0,000 7,103E-03 0,02241732 ! biogenic amine catabolic process GO:0042402 7 7 0,000 7,103E-03 0,022379 ! regulation of axon extension GO:0030516 7 7 0,000 7,103E-03 0,02234081 ! cell killing GO:0001906 7 7 0,000 7,103E-03 0,02230275 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 7,103E-03 0,02226482 ! adult feeding behavior GO:0008343 7 7 0,000 7,103E-03 0,02222702 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 7,103E-03 0,02218934 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 7,103E-03 0,0221518 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 7,103E-03 0,02211438 ! negative regulation of T cell activation GO:0050868 7 7 0,000 7,103E-03 0,02207709 ! response to cold GO:0009409 7 7 0,000 7,103E-03 0,02203992 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 8,115E-03 0,02513518 ! negative regulation of muscle development GO:0048635 8 8 0,000 8,115E-03 0,02509301 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 8,115E-03 0,02505098 ! positive regulation of translation GO:0045727 8 8 0,000 8,115E-03 0,02500909 ! positive regulation of cell killing GO:0031343 8 8 0,000 8,115E-03 0,02496734 ! superoxide anion generation GO:0042554 8 8 0,000 8,115E-03 0,02492572 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 8,115E-03 0,02488425 ! cGMP metabolic process GO:0046068 8 8 0,000 8,115E-03 0,02484291 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 8 8 0,000 8,115E-03 0,02480172 ! dicarboxylic acid transport GO:0006835 8 8 0,000 8,115E-03 0,02476065 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 8,115E-03 0,02471973 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 8,115E-03 0,02467893 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 8,115E-03 0,02463828 ! zinc ion transport GO:0006829 8 8 0,000 8,115E-03 0,02459775 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 8,115E-03 0,02455736 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 8,115E-03 0,02451711 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 8,115E-03 0,02447698 ! cardiac muscle contraction GO:0060048 8 8 0,000 8,115E-03 0,02443698 ! lipid localization GO:0010876 8 8 0,000 8,115E-03 0,02439712 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 8,115E-03 0,02435738 ! response to cAMP GO:0051591 8 8 0,000 8,115E-03 0,02431778 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 8,115E-03 0,0242783 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 8,115E-03 0,02423895 ! negative regulation of ion transport GO:0043271 8 8 0,000 8,115E-03 0,02419973 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 8,115E-03 0,02416064 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 8,115E-03 0,02412167 ! sensory perception of taste GO:0050909 8 8 0,000 8,115E-03 0,02408282 ! organelle fusion GO:0048284 8 8 0,000 8,115E-03 0,02404411 ! pancreas development GO:0031016 8 8 0,000 8,115E-03 0,02400551 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 8,115E-03 0,02396704 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 8,115E-03 0,02392869 ! negative regulation of proteolysis GO:0045861 8 8 0,000 8,115E-03 0,02389047 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 8,115E-03 0,02385237 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 8,115E-03 0,02381439 ! sperm motility GO:0030317 8 8 0,000 8,115E-03 0,02377653 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 8,115E-03 0,02373878 ! DNA duplex unwinding GO:0032508 8 8 0,000 8,115E-03 0,02370116 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 8,115E-03 0,02366366 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 8,115E-03 0,02362628 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 8,115E-03 0,02358901 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 8,115E-03 0,02355186 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 8,115E-03 0,02351483 ! Golgi organization GO:0007030 8 8 0,000 8,115E-03 0,02347792 ! cell-cell junction assembly GO:0007043 8 8 0,000 8,115E-03 0,02344112 ! regulation of stress fiber formation GO:0051492 9 8 0,000 8,115E-03 0,02340444 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 8,115E-03 0,02336787 ! fructose metabolic process GO:0006000 8 8 0,000 8,115E-03 0,02333141 ! mannose metabolic process GO:0006013 9 8 0,000 8,115E-03 0,02329507 ! NAD metabolic process GO:0019674 8 8 0,000 8,115E-03 0,02325884 ! sex determination GO:0007530 8 8 0,000 8,115E-03 0,02322272 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 8,115E-03 0,02318672 ! plasma membrane fusion GO:0045026 8 8 0,000 8,115E-03 0,02315083 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 8,115E-03 0,02311505 ! response to fungus GO:0009620 8 8 0,000 8,115E-03 0,02307937 ! stem cell differentiation GO:0048863 8 8 0,000 8,115E-03 0,02304381 ! alpha-beta T cell activation GO:0046631 8 8 0,000 8,115E-03 0,02300836 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 8,115E-03 0,02297302 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 8,115E-03 0,02293778 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 8,115E-03 0,02290266 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 8,115E-03 0,02286764 ! regulation of vasodilation GO:0042312 8 8 0,000 8,115E-03 0,02283272 ! vasoconstriction GO:0042310 8 8 0,000 8,115E-03 0,02279792 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 8,115E-03 0,02276322 ! muscle cell development GO:0055001 8 8 0,000 8,115E-03 0,02272862 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 8,115E-03 0,02269413 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 8,115E-03 0,02265975 ! sensory perception of pain GO:0019233 8 8 0,000 8,115E-03 0,02262547 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 8,115E-03 0,02259129 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 8,115E-03 0,02255722 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 8,115E-03 0,02252324 ! chromatin silencing GO:0006342 8 8 0,000 8,115E-03 0,02248937 ! tissue regeneration GO:0042246 8 8 0,000 8,115E-03 0,02245561 ! salivary gland development GO:0007431 8 8 0,000 8,115E-03 0,02242194 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 8,115E-03 0,02238837 ! T cell homeostasis GO:0043029 8 8 0,000 8,115E-03 0,02235491 ! peptide biosynthetic process GO:0043043 9 8 0,000 8,115E-03 0,02232154 ! peptidyl-serine modification GO:0018209 8 8 0,000 8,115E-03 0,02228828 ! water homeostasis GO:0030104 8 8 0,000 8,115E-03 0,02225511 ! cofactor transport GO:0051181 8 8 0,000 8,115E-03 0,02222204 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 8,115E-03 0,02218907 ! acid secretion GO:0046717 8 8 0,000 8,115E-03 0,0221562 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 8,115E-03 0,02212342 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 8,115E-03 0,02209074 ! protein-chromophore linkage GO:0018298 9 8 0,000 8,115E-03 0,02205816 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 8,115E-03 0,02202568 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 8,115E-03 0,02199329 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 8,115E-03 0,02196099 ! regulation of RNA stability GO:0043487 8 8 0,000 8,115E-03 0,02192879 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 8,115E-03 0,02189668 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 8,115E-03 0,02186467 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 8,115E-03 0,02183275 ! regulation of organic acid transport GO:0032890 8 8 0,000 8,115E-03 0,02180092 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 8,115E-03 0,02176919 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 8,115E-03 0,02173755 ! regulation of multi-organism process GO:0043900 8 8 0,000 8,115E-03 0,021706 ! positive regulation of amine transport GO:0051954 8 8 0,000 8,115E-03 0,02167454 ! peptide hormone secretion GO:0030072 8 8 0,000 8,115E-03 0,02164318 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 8,115E-03 0,0216119 ! actin filament polymerization GO:0030041 9 8 0,000 8,115E-03 0,02158071 ! peptide hormone processing GO:0016486 8 8 0,000 8,115E-03 0,02154962 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 8,115E-03 0,02151861 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 8,115E-03 0,02148769 ! lactation GO:0007595 10 9 0,000 9,125E-03 0,02412845 ! embryonic pattern specification GO:0009880 10 9 0,000 9,125E-03 0,02409388 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 9,125E-03 0,02405941 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 9,125E-03 0,02402504 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 9,125E-03 0,02399077 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 9,125E-03 0,02395659 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 9,125E-03 0,02392252 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 9,125E-03 0,02388853 ! viral genome replication GO:0019079 9 9 0,000 9,125E-03 0,02385465 ! phospholipid catabolic process GO:0009395 9 9 0,000 9,125E-03 0,02382086 ! copper ion transport GO:0006825 9 9 0,000 9,125E-03 0,02378717 ! lipid phosphorylation GO:0046834 9 9 0,000 9,125E-03 0,02375357 ! aminoglycan catabolic process GO:0006026 9 9 0,000 9,125E-03 0,02372007 ! Golgi vesicle budding GO:0048194 9 9 0,000 9,125E-03 0,02368666 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 9,125E-03 0,02365335 ! RNA polyadenylation GO:0043631 9 9 0,000 9,125E-03 0,02362012 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 9,125E-03 0,023587 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 9,125E-03 0,02355396 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 9,125E-03 0,02352102 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 9,125E-03 0,02348817 ! phospholipid efflux GO:0033700 9 9 0,000 9,125E-03 0,02345541 ! response to alkaloid GO:0043279 10 9 0,000 9,125E-03 0,02342274 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 9,125E-03 0,02339016 ! cytokine biosynthetic process GO:0042089 9 9 0,000 9,125E-03 0,02335768 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 9,125E-03 0,02332528 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 9,125E-03 0,02329298 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 9,125E-03 0,02326076 ! response to ethanol GO:0045471 9 9 0,000 9,125E-03 0,02322863 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 9,125E-03 0,02319659 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 9,125E-03 0,02316464 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 9,125E-03 0,02313278 ! methionine metabolic process GO:0006555 9 9 0,000 9,125E-03 0,023101 ! glutamine metabolic process GO:0006541 9 9 0,000 9,125E-03 0,02306931 ! cerebral cortex development GO:0021987 9 9 0,000 9,125E-03 0,02303771 ! response to osmotic stress GO:0006970 9 9 0,000 9,125E-03 0,02300619 ! pigmentation during development GO:0048066 9 9 0,000 9,125E-03 0,02297477 ! reverse cholesterol transport GO:0043691 9 9 0,000 9,125E-03 0,02294342 ! central nervous system neuron development GO:0021954 10 9 0,000 9,125E-03 0,02291216 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 9,125E-03 0,02288099 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 9,125E-03 0,0228499 ! substrate-bound cell migration GO:0006929 9 9 0,000 9,125E-03 0,0228189 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 9,125E-03 0,02278798 ! L-glutamate transport GO:0015813 9 9 0,000 9,125E-03 0,02275714 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 9,125E-03 0,02272639 ! regulation of dephosphorylation GO:0035303 9 9 0,000 9,125E-03 0,02269572 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 9,125E-03 0,02266513 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 9,125E-03 0,02263463 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 9,125E-03 0,02260421 ! behavioral interaction between organisms GO:0051705 9 9 0,000 9,125E-03 0,02257386 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 9,125E-03 0,0225436 ! DNA replication initiation GO:0006270 9 9 0,000 9,125E-03 0,02251343 ! prostaglandin metabolic process GO:0006693 9 9 0,000 9,125E-03 0,02248333 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 9,125E-03 0,02245331 ! regulation of cellular pH GO:0030641 9 9 0,000 9,125E-03 0,02242337 ! histone acetylation GO:0016573 9 9 0,000 9,125E-03 0,02239351 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 9,125E-03 0,02236373 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 9,125E-03 0,02233404 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 9,125E-03 0,02230441 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 9,125E-03 0,02227487 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 9,125E-03 0,02224541 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 9,125E-03 0,02221602 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 9,125E-03 0,02218671 ! negative regulation of protein secretion GO:0050709 9 9 0,000 9,125E-03 0,02215748 ! regulation of leukocyte migration GO:0002685 9 9 0,000 9,125E-03 0,02212833 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 9,125E-03 0,02209925 ! collagen catabolic process GO:0030574 9 9 0,000 9,125E-03 0,02207025 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 9,125E-03 0,02204132 ! purine base metabolic process GO:0006144 9 9 0,000 9,125E-03 0,02201247 ! gas transport GO:0015669 9 9 0,000 9,125E-03 0,0219837 ! cholesterol efflux GO:0033344 9 9 0,000 9,125E-03 0,021955 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 9,125E-03 0,02192637 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 9,125E-03 0,02189782 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 9,125E-03 0,02186935 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 9,125E-03 0,02184095 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 9,125E-03 0,02181262 ! defense response to virus GO:0051607 9 9 0,000 9,125E-03 0,02178436 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 9,125E-03 0,02175618 ! actin filament-based movement GO:0030048 9 9 0,000 9,125E-03 0,02172807 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 9,125E-03 0,02170004 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01013456 0,02406958 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,01013456 0,02403861 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01013456 0,02400771 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01013456 0,02397689 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,01013456 0,02394615 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01013456 0,02391549 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01013456 0,02388491 ! neuron maturation GO:0042551 10 10 0,000 0,01013456 0,0238544 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01013456 0,02382398 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01013456 0,02379363 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01013456 0,02376335 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01013456 0,02373316 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01013456 0,02370304 ! hormone secretion GO:0046879 10 10 0,000 0,01013456 0,023673 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01013456 0,02364303 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01013456 0,02361314 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,01013456 0,02358333 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01013456 0,02355359 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01013456 0,02352393 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01013456 0,02349434 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01013456 0,02346482 ! glial cell development GO:0021782 10 10 0,000 0,01013456 0,02343538 ! phototransduction GO:0007602 11 10 0,000 0,01013456 0,02340601 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01013456 0,02337672 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01013456 0,0233475 ! fat cell differentiation GO:0045444 10 10 0,000 0,01013456 0,02331835 ! myoblast differentiation GO:0045445 10 10 0,000 0,01013456 0,02328927 ! centrosome cycle GO:0007098 10 10 0,000 0,01013456 0,02326027 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01013456 0,02323134 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01013456 0,02320248 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01013456 0,02317369 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01013456 0,02314498 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01013456 0,02311633 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,01013456 0,02308776 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01013456 0,02305926 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01013456 0,02303082 ! plasma membrane organization GO:0007009 10 10 0,000 0,01013456 0,02300246 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01013456 0,02297417 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01013456 0,02294594 ! lysosomal transport GO:0007041 10 10 0,000 0,01013456 0,02291779 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01013456 0,0228897 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01013456 0,02286169 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,01013456 0,02283374 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,01013456 0,02280586 ! exocrine system development GO:0035272 10 10 0,000 0,01013456 0,02277804 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01013456 0,0227503 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01013456 0,02272262 ! embryo implantation GO:0007566 11 10 0,000 0,01013456 0,02269501 ! regulation of protein binding GO:0043393 11 10 0,000 0,01013456 0,02266747 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01013456 0,02264 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01013456 0,02261259 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,01013456 0,02258524 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01013456 0,02255797 ! protein export from nucleus GO:0006611 10 10 0,000 0,01013456 0,02253076 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01013456 0,02250361 ! cytolysis GO:0019835 10 10 0,000 0,01013456 0,02247653 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01013456 0,02244952 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01013456 0,02242257 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01013456 0,02239568 ! histone deacetylation GO:0016575 10 10 0,000 0,01013456 0,02236886 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01013456 0,0223421 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01013456 0,02231541 ! gland morphogenesis GO:0022612 10 10 0,000 0,01013456 0,02228878 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01013456 0,02226221 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01013456 0,02223571 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01013456 0,02220927 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01013456 0,02218289 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,01013456 0,02215658 ! regulation of epidermis development GO:0045682 10 10 0,000 0,01013456 0,02213033 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01013456 0,02210414 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,01013456 0,02207801 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01013456 0,02205194 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01013456 0,02202594 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01013456 0,022 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01013456 0,02197411 ! nerve development GO:0021675 10 10 0,000 0,01013456 0,02194829 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,01013456 0,02192253 ! gut development GO:0048565 10 10 0,000 0,01013456 0,02189683 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01013456 0,02187119 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,01013456 0,02184561 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01013456 0,02182009 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01013456 0,02179463 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01013456 0,02176923 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01013456 0,02174388 ! protein stabilization GO:0050821 10 10 0,000 0,01013456 0,0217186 ! protein secretion GO:0009306 11 11 0,000 0,01114316 0,02385231 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01114316 0,02382464 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01114316 0,02379703 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01114316 0,02376949 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01114316 0,02374201 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01114316 0,0237146 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,01114316 0,02368724 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01114316 0,02365995 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01114316 0,02363273 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,01114316 0,02360556 ! signal complex assembly GO:0007172 11 11 0,000 0,01114316 0,02357846 ! microtubule-based transport GO:0010970 11 11 0,000 0,01114316 0,02355142 ! endothelial cell migration GO:0043542 11 11 0,000 0,01114316 0,02352444 ! peroxisomal transport GO:0043574 11 11 0,000 0,01114316 0,02349753 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01114316 0,02347067 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,01114316 0,02344388 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01114316 0,02341715 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01114316 0,02339048 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01114316 0,02336387 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01114316 0,02333732 ! T cell proliferation GO:0042098 11 11 0,000 0,01114316 0,02331083 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01114316 0,0232844 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01114316 0,02325803 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,01114316 0,02323172 ! spinal cord development GO:0021510 11 11 0,000 0,01114316 0,02320547 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01114316 0,02317928 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01114316 0,02315315 ! cellular response to starvation GO:0009267 11 11 0,000 0,01114316 0,02312707 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01114316 0,02310106 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,01114316 0,0230751 ! digestive system process GO:0022600 11 11 0,000 0,01114316 0,0230492 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01114316 0,02302336 ! fucose metabolic process GO:0006004 11 11 0,000 0,01114316 0,02299758 ! membrane budding GO:0006900 11 11 0,000 0,01114316 0,02297186 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,01114316 0,02294619 ! monoamine transport GO:0015844 11 11 0,000 0,01114316 0,02292058 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01114316 0,02289503 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01114316 0,02286953 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01114316 0,02284409 ! body fluid secretion GO:0007589 11 11 0,000 0,01114316 0,02281871 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01114316 0,02279339 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,01114316 0,02276812 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01114316 0,0227429 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01114316 0,02271774 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01114316 0,02269264 ! membrane depolarization GO:0051899 11 11 0,000 0,01114316 0,02266759 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01114316 0,0226426 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01114316 0,02261767 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,01114316 0,02259278 ! oogenesis GO:0048477 11 11 0,000 0,01114316 0,02256796 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01114316 0,02254318 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01114316 0,02251847 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,01114316 0,0224938 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,01114316 0,02246919 ! muscle maintenance GO:0046716 12 11 0,000 0,01114316 0,02244463 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01114316 0,02242013 ! hindbrain development GO:0030902 11 11 0,000 0,01114316 0,02239568 ! steroid catabolic process GO:0006706 11 11 0,000 0,01114316 0,02237129 ! endocrine process GO:0050886 11 11 0,000 0,01114316 0,02234694 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01114316 0,02232265 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01114316 0,02229841 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01114316 0,02227423 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,01114316 0,0222501 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01114316 0,02222602 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,01215087 0,02420979 ! translational initiation GO:0006413 12 12 0,000 0,01215087 0,02418365 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,01215087 0,02415756 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,01215087 0,02413153 ! initiation of viral infection GO:0019059 12 12 0,000 0,01215087 0,02410555 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,01215087 0,02407963 ! iron ion transport GO:0006826 13 12 0,000 0,01215087 0,02405377 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,01215087 0,02402796 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,01215087 0,02400221 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,01215087 0,02397651 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,01215087 0,02395087 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,01215087 0,02392528 ! collagen metabolic process GO:0032963 12 12 0,000 0,01215087 0,02389974 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,01215087 0,02387426 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,01215087 0,02384884 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,01215087 0,02382347 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,01215087 0,02379815 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,01215087 0,02377289 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,01215087 0,02374768 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,01215087 0,02372252 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,01215087 0,02369742 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,01215087 0,02367237 ! retinoid metabolic process GO:0001523 12 12 0,000 0,01215087 0,02364737 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,01215087 0,02362243 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,01215087 0,02359753 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,01215087 0,02357269 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,01215087 0,02354791 ! acute-phase response GO:0006953 12 12 0,000 0,01215087 0,02352317 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01215087 0,02349849 ! vacuolar transport GO:0007034 12 12 0,000 0,01215087 0,02347386 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,01215087 0,02344928 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,01215087 0,02342475 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,01215087 0,02340027 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,01215087 0,02337585 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,01215087 0,02335147 ! male gonad development GO:0008584 12 12 0,000 0,01215087 0,02332715 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,01215087 0,02330287 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,01215087 0,02327865 ! renal system process GO:0003014 12 12 0,000 0,01215087 0,02325448 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,01215087 0,02323035 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,01215087 0,02320628 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,01215087 0,02318226 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,01215087 0,02315828 ! pallium development GO:0021543 13 12 0,000 0,01215087 0,02313436 ! cell fate determination GO:0001709 12 12 0,000 0,01215087 0,02311048 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,01215087 0,02308666 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,01215087 0,02306288 ! somitogenesis GO:0001756 13 12 0,000 0,01215087 0,02303916 ! G1 phase GO:0051318 13 12 0,000 0,01215087 0,02301548 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,01215087 0,02299185 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,01215087 0,02296827 ! detection of light stimulus GO:0009583 13 12 0,000 0,01215087 0,02294473 ! synaptogenesis GO:0007416 12 12 0,000 0,01215087 0,02292125 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,01215087 0,02289781 ! hormone transport GO:0009914 12 12 0,000 0,01215087 0,02287442 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,01215087 0,02285108 ! heme biosynthetic process GO:0006783 12 12 0,000 0,01215087 0,02282779 ! spermatid differentiation GO:0048515 13 12 0,000 0,01215087 0,02280454 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,01215087 0,02278134 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,01215087 0,02275819 ! neural tube closure GO:0001843 13 12 0,000 0,01215087 0,02273509 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,01215087 0,02271203 ! negative regulation of translation GO:0017148 12 12 0,000 0,01215087 0,02268902 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,01215087 0,02266605 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,01215087 0,02264313 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,01315771 0,0244946 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,01315771 0,02446989 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,01315771 0,02444522 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,01315771 0,0244206 ! phenol metabolic process GO:0018958 13 13 0,000 0,01315771 0,02439603 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,01315771 0,02437151 ! gluconeogenesis GO:0006094 13 13 0,000 0,01315771 0,02434705 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,01315771 0,02432262 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,01315771 0,02429825 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,01315771 0,02427393 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,01315771 0,02424966 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,01315771 0,02422543 ! regeneration GO:0031099 13 13 0,000 0,01315771 0,02420125 ! keratinization GO:0031424 13 13 0,000 0,01315771 0,02417713 ! post-embryonic development GO:0009791 14 13 0,000 0,01315771 0,02415304 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,01315771 0,02412901 ! patterning of blood vessels GO:0001569 13 13 0,000 0,01315771 0,02410503 ! vasculogenesis GO:0001570 13 13 0,000 0,01315771 0,02408109 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,01315771 0,0240572 ! regulation of innate immune response GO:0045088 13 13 0,000 0,01315771 0,02403336 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,01315771 0,02400956 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,01315771 0,02398581 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,01315771 0,02396211 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,01315771 0,02393846 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,01315771 0,02391485 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,01315771 0,02389129 ! autophagy GO:0006914 13 13 0,000 0,01315771 0,02386777 ! receptor metabolic process GO:0043112 14 13 0,000 0,01315771 0,0238443 ! actin filament bundle formation GO:0051017 13 13 0,000 0,01315771 0,02382088 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,01315771 0,0237975 ! cell aging GO:0007569 13 13 0,000 0,01315771 0,02377417 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,01315771 0,02375089 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,01315771 0,02372765 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,01315771 0,02370445 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,01315771 0,02368131 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,01315771 0,0236582 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,01315771 0,02363514 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,01315771 0,02361213 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,01315771 0,02358916 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,01315771 0,02356624 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,01315771 0,02354336 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,01315771 0,02352052 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,01315771 0,02349773 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,01315771 0,02347498 ! vasodilation GO:0042311 14 13 0,000 0,01315771 0,02345228 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,01315771 0,02342962 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,01315771 0,023407 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,01315771 0,02338443 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,01315771 0,0233619 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,01315771 0,02333942 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,01315771 0,02331698 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,01315771 0,02329458 ! immunoglobulin production GO:0002377 13 13 0,000 0,01315771 0,02327222 GO:0002440|production of molecular mediator of immune response, ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,01315771 0,02324991 ! cell-cell junction organization GO:0045216 13 13 0,000 0,01315771 0,02322764 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,01315771 0,02320541 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,01315771 0,02318323 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,01315771 0,02316109 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,01315771 0,02313899 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,01315771 0,02311693 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,01315771 0,02309491 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,01315771 0,02307294 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,01315771 0,023051 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,01315771 0,02302911 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,01315771 0,02300726 ! blastocyst development GO:0001824 13 13 0,000 0,01315771 0,02298546 ! telomere organization GO:0032200 13 13 0,000 0,01315771 0,02296369 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,01315771 0,02294197 ! regulation of amine transport GO:0051952 13 13 0,000 0,01315771 0,02292028 ! tissue homeostasis GO:0001894 13 13 0,000 0,01315771 0,02289864 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,01315771 0,02287703 ! protein tetramerization GO:0051262 13 13 0,000 0,01315771 0,02285547 ! neuron fate commitment GO:0048663 14 14 0,000 0,01416366 0,02457969 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,01416366 0,02455657 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,01416366 0,02453349 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,01416366 0,02451045 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,01416366 0,02448746 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,01416366 0,02446451 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,01416366 0,0244416 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,01416366 0,02441874 ! protein amino acid acylation GO:0043543 14 14 0,000 0,01416366 0,02439592 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,01416366 0,02437314 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,01416366 0,0243504 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,01416366 0,02432771 ! vesicle docking GO:0048278 14 14 0,000 0,01416366 0,02430506 ! superoxide metabolic process GO:0006801 15 14 0,000 0,01416366 0,02428245 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,01416366 0,02425988 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,01416366 0,02423736 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,01416366 0,02421487 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,01416366 0,02419243 ! hair cycle GO:0042633 14 14 0,000 0,01416366 0,02417003 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,01416366 0,02414767 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,01416366 0,02412535 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,01416366 0,02410308 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,01416366 0,02408084 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,01416366 0,02405865 ! lysosome organization GO:0007040 14 14 0,000 0,01416366 0,02403649 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,01416366 0,02401438 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,01416366 0,02399231 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,01416366 0,02397028 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,01416366 0,02394829 ! primary neural tube formation GO:0014020 15 14 0,000 0,01416366 0,02392634 ! peptide cross-linking GO:0018149 14 14 0,000 0,01416366 0,02390443 ! regulation of behavior GO:0050795 14 14 0,000 0,01416366 0,02388256 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,01416366 0,02386072 ! base-excision repair GO:0006284 14 14 0,000 0,01416366 0,02383893 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,01416366 0,02381718 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,01416366 0,02379547 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,01416366 0,0237738 ! formation of primary germ layer GO:0001704 14 14 0,000 0,01416366 0,02375217 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,01416366 0,02373058 ! collagen fibril organization GO:0030199 14 14 0,000 0,01416366 0,02370902 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,01416366 0,02368751 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,01416366 0,02366603 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,01416366 0,0236446 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,01416366 0,0236232 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,01416366 0,02360184 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,01416366 0,02358052 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,01416366 0,02355924 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,01416366 0,02353799 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,01416366 0,02351679 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,01516874 0,02516291 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,01516874 0,02514028 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,01516874 0,02511769 ! positive regulation of ossification GO:0045778 15 15 0,000 0,01516874 0,02509514 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,01516874 0,02507264 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,01516874 0,02505017 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,01516874 0,02502774 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,01516874 0,02500536 ! response to vitamin GO:0033273 15 15 0,000 0,01516874 0,02498301 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,01516874 0,0249607 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,01516874 0,02493844 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,01516874 0,02491621 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,01516874 0,02489402 ! ovarian follicle development GO:0001541 15 15 0,000 0,01516874 0,02487188 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,01516874 0,02484977 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,01516874 0,0248277 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,01516874 0,02480567 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,01516874 0,02478368 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,01516874 0,02476173 ! heme metabolic process GO:0042168 15 15 0,000 0,01516874 0,02473981 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,01516874 0,02471794 ! chromosome condensation GO:0030261 15 15 0,000 0,01516874 0,0246961 ! response to starvation GO:0042594 15 15 0,000 0,01516874 0,02467431 ! response to ionizing radiation GO:0010212 16 15 0,000 0,01516874 0,02465255 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,01516874 0,02463083 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,01516874 0,02460914 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,01516874 0,0245875 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,01516874 0,0245659 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,01516874 0,02454433 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,01516874 0,0245228 ! phospholipid transport GO:0015914 15 15 0,000 0,01516874 0,0245013 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,01516874 0,02447985 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,01516874 0,02445843 ! glutathione metabolic process GO:0006749 16 15 0,000 0,01516874 0,02443705 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,01516874 0,02441571 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,01516874 0,02439441 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,01516874 0,02437314 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,01516874 0,02435191 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,01516874 0,02433071 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,01516874 0,02430956 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,01516874 0,02428843 ! protein homooligomerization GO:0051260 15 15 0,000 0,01516874 0,02426735 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,01516874 0,0242463 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,01617294 0,02582905 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,01617294 0,02580669 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,01617294 0,02578436 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,01617294 0,02576208 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,01617294 0,02573983 ! learning GO:0007612 16 16 0,000 0,01617294 0,02571762 ! circadian rhythm GO:0007623 16 16 0,000 0,01617294 0,02569545 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,01617294 0,02567332 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,01617294 0,02565123 ! vacuole organization GO:0007033 16 16 0,000 0,01617294 0,02562917 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,01617294 0,02560715 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,01617294 0,02558517 ! vesicle targeting GO:0006903 17 16 0,000 0,01617294 0,02556323 ! segmentation GO:0035282 17 16 0,000 0,01617294 0,02554132 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,01617294 0,02551946 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,01617294 0,02549763 ! iron ion homeostasis GO:0055072 16 16 0,000 0,01617294 0,02547583 ! positive regulation of cell development GO:0010720 16 16 0,000 0,01617294 0,02545408 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,01617294 0,02543236 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,01617294 0,02541068 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,01617294 0,02538903 ! pentose metabolic process GO:0019321 16 16 0,000 0,01617294 0,02536743 ! fatty acid transport GO:0015908 16 16 0,000 0,01617294 0,02534585 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,01617294 0,02532432 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,01617294 0,02530282 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,01617294 0,02528136 ! cofactor catabolic process GO:0051187 16 16 0,000 0,01617294 0,02525994 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,01617294 0,02523855 ! polyol metabolic process GO:0019751 16 16 0,000 0,01617294 0,0252172 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,01617294 0,02519588 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,01617294 0,0251746 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,01617294 0,02515335 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,01617294 0,02513215 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,01617294 0,02511097 ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,01617294 0,02508984 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,01617294 0,02506873 ! regulation of coagulation GO:0050818 17 16 0,000 0,01617294 0,02504767 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,01717626 0,02657921 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,01717626 0,02655692 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,01717626 0,02653466 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,01717626 0,02651243 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,01717626 0,02649025 ! myelination GO:0042552 17 17 0,000 0,01717626 0,0264681 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,01717626 0,02644599 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,01717626 0,02642391 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,01717626 0,02640187 ! leukocyte adhesion GO:0007159 17 17 0,000 0,01717626 0,02637987 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,01717626 0,02635791 ! sensory perception of smell GO:0007608 17 17 0,000 0,01717626 0,02633598 ! glucose transport GO:0015758 17 17 0,000 0,01717626 0,02631409 ! cell junction assembly GO:0034329 18 17 0,000 0,01717626 0,02629223 ! tissue remodeling GO:0048771 17 17 0,000 0,01717626 0,02627041 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,01717626 0,02624863 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,01717626 0,02622688 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,01717626 0,02620517 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,01717626 0,02618349 ! neural crest cell development GO:0014032 19 17 0,000 0,01717626 0,02616185 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,01717626 0,02614025 ! negative regulation of cell development GO:0010721 18 17 0,000 0,01717626 0,02611868 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,01717626 0,02609715 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,01717626 0,02607565 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,01717626 0,02605419 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,01717626 0,02603277 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,01717626 0,02601138 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,01717626 0,02599002 ! pigmentation GO:0043473 17 17 0,000 0,01717626 0,0259687 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,01717626 0,02594741 ! adult locomotory behavior GO:0008344 17 17 0,000 0,01717626 0,02592616 ! embryonic organ development GO:0048568 17 17 0,000 0,01717626 0,02590495 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,01717626 0,02588376 ! liver development GO:0001889 17 17 0,000 0,01717626 0,02586262 ! gene silencing GO:0016458 17 17 0,000 0,01717626 0,02584151 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,0181787 0,02732736 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,0181787 0,02730509 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,0181787 0,02728286 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,0181787 0,02726066 ! meiosis I GO:0007127 18 18 0,000 0,0181787 0,02723849 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,0181787 0,02721637 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,0181787 0,02719428 ! membrane docking GO:0022406 18 18 0,000 0,0181787 0,02717222 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,0181787 0,0271502 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,0181787 0,02712822 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,0181787 0,02710627 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,0181787 0,02708435 ! hexose transport GO:0008645 18 18 0,000 0,0181787 0,02706248 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,0181787 0,02704064 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,0181787 0,02701883 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,0181787 0,02699706 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,0181787 0,02697532 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,0181787 0,02695362 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,0181787 0,02693195 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,0181787 0,02691032 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,0181787 0,02688872 ! B cell differentiation GO:0030183 18 18 0,000 0,0181787 0,02686716 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,0181787 0,02684563 ! ensheathment of neurons GO:0007272 18 18 0,000 0,0181787 0,02682414 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,0181787 0,02680268 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,0181787 0,02678125 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,0181787 0,02675986 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,0181787 0,02673851 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,0181787 0,02671718 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,01918027 0,02816672 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,01918027 0,02814429 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,01918027 0,0281219 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,01918027 0,02809955 ! glial cell differentiation GO:0010001 19 19 0,000 0,01918027 0,02807723 ! regulation of pH GO:0006885 19 19 0,000 0,01918027 0,02805495 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,01918027 0,0280327 ! feeding behavior GO:0007631 19 19 0,000 0,01918027 0,02801049 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,01918027 0,02798831 ! peroxisome organization GO:0007031 19 19 0,000 0,01918027 0,02796617 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,01918027 0,02794406 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,01918027 0,02792199 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,01918027 0,02789995 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,01918027 0,02787794 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,01918027 0,02785598 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,01918027 0,02783404 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,01918027 0,02781214 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,01918027 0,02779028 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,01918027 0,02776845 ! peripheral nervous system development GO:0007422 19 19 0,000 0,01918027 0,02774665 ! regulation of protein stability GO:0031647 19 19 0,000 0,01918027 0,02772489 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,01918027 0,02770316 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,01918027 0,02768147 ! eye morphogenesis GO:0048592 19 19 0,000 0,01918027 0,02765981 ! regulation of cell shape GO:0008360 21 19 0,000 0,01918027 0,02763818 ! placenta development GO:0001890 19 19 0,000 0,01918027 0,02761659 ! response to heat GO:0009408 19 19 0,000 0,01918027 0,02759503 ! vesicle localization GO:0051648 20 19 0,000 0,01918027 0,02757351 ! regulation of muscle development GO:0048634 21 20 0,000 0,02018096 0,02898948 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,02018096 0,02896691 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,02018096 0,02894436 ! organic ether metabolic process GO:0018904 20 20 0,000 0,02018096 0,02892186 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,02018096 0,02889938 ! neural tube development GO:0021915 21 20 0,000 0,02018096 0,02887695 ! nucleus organization GO:0006997 20 20 0,000 0,02018096 0,02885454 ! phagocytosis GO:0006909 21 20 0,000 0,02018096 0,02883218 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,02018096 0,02880984 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,02018096 0,02878754 ! protein targeting to membrane GO:0006612 22 20 0,000 0,02018096 0,02876528 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,02018096 0,02874305 ! chromatin remodeling GO:0006338 20 20 0,000 0,02018096 0,02872085 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,02018096 0,02869869 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,02018096 0,02867657 ! lipid oxidation GO:0034440 20 20 0,000 0,02018096 0,02865447 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,02018096 0,02863241 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,02018096 0,02861039 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,02018096 0,0285884 ! RNA modification GO:0009451 20 20 0,000 0,02018096 0,02856644 ! single fertilization GO:0007338 21 20 0,000 0,02018096 0,02854452 ! regulation of B cell activation GO:0050864 20 20 0,000 0,02018096 0,02852263 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,02118077 0,02991277 ! mRNA catabolic process GO:0006402 21 21 0,000 0,02118077 0,02988987 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,02118077 0,029867 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,02118077 0,02984416 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,02118077 0,02982136 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,02118077 0,0297986 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,02118077 0,02977587 ! Notch signaling pathway GO:0007219 22 21 0,000 0,02118077 0,02975318 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,02118077 0,02973052 ! organic anion transport GO:0015711 21 21 0,000 0,02118077 0,02970789 ! cholesterol transport GO:0030301 21 21 0,000 0,02118077 0,0296853 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,02118077 0,02966274 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,02118077 0,02964022 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,02118077 0,02961773 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,02118077 0,02959527 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,02118077 0,02957285 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,02118077 0,02955047 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,02118077 0,02952811 ! regulation of proteolysis GO:0030162 21 21 0,000 0,02118077 0,02950579 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,02118077 0,02948351 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,02118077 0,02946126 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,02217971 0,03082746 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,02217971 0,03080423 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,02217971 0,03078103 ! sister chromatid segregation GO:0000819 22 22 0,000 0,02217971 0,03075787 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,02217971 0,03073475 ! regulation of ion transport GO:0043269 22 22 0,000 0,02217971 0,03071166 ! odontogenesis GO:0042476 22 22 0,000 0,02217971 0,0306886 ! cell junction organization GO:0034330 23 22 0,000 0,02217971 0,03066558 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,02217971 0,03064259 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,02217971 0,03061964 ! ovulation cycle process GO:0022602 22 22 0,000 0,02217971 0,03059672 ! spindle organization GO:0007051 22 22 0,000 0,02217971 0,03057383 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,02217971 0,03055098 ! cell chemotaxis GO:0060326 23 22 0,000 0,02217971 0,03052817 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,02217971 0,03050538 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,02217971 0,03048264 ! male sex differentiation GO:0046661 22 22 0,000 0,02217971 0,03045992 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,02217971 0,03043724 ! biopolymer methylation GO:0043414 22 22 0,000 0,02217971 0,03041459 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,02217971 0,03039198 ! detection of external stimulus GO:0009581 23 22 0,000 0,02217971 0,0303694 ! neuron migration GO:0001764 22 22 0,000 0,02217971 0,03034686 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,02217971 0,03032434 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,02217971 0,03030186 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,02217971 0,03027942 ! aerobic respiration GO:0009060 22 22 0,000 0,02217971 0,03025701 ! cytokine production GO:0001816 22 22 0,000 0,02217971 0,03023463 ! cytokinesis GO:0000910 23 22 0,000 0,02217971 0,03021228 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,02217971 0,03018997 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,02317778 0,0315252 ! viral infectious cycle GO:0019058 23 23 0,000 0,02317778 0,03150196 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,02317778 0,03147874 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,02317778 0,03145556 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,02317778 0,03143241 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,02317778 0,0314093 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,02317778 0,03138622 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,02317778 0,03136318 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,02317778 0,03134017 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,02317778 0,03131719 ! female gonad development GO:0008585 23 23 0,000 0,02317778 0,03129425 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,02317778 0,03127134 ! lipid homeostasis GO:0055088 23 23 0,000 0,02317778 0,03124846 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,02317778 0,03122562 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,02317778 0,03120281 ! cell projection assembly GO:0030031 25 23 0,000 0,02317778 0,03118004 ! mitochondrial transport GO:0006839 24 24 0,000 0,02417497 0,0324978 ! regulation of action potential GO:0001508 24 24 0,000 0,02417497 0,03247411 ! gliogenesis GO:0042063 24 24 0,000 0,02417497 0,03245046 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,02417497 0,03242684 ! glucose homeostasis GO:0042593 24 24 0,000 0,02417497 0,03240326 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,02417497 0,03237971 ! T cell differentiation GO:0030217 24 24 0,000 0,02417497 0,03235619 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,02417497 0,03233271 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,02417497 0,03230927 ! ovulation cycle GO:0042698 24 24 0,000 0,02417497 0,03228585 ! fertilization GO:0009566 25 24 0,000 0,02417497 0,03226248 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,02417497 0,03223913 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,02417497 0,03221582 ! glucan metabolic process GO:0044042 25 24 0,000 0,02417497 0,03219254 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,0251713 0,03349509 ! negative regulation of secretion GO:0051048 26 25 0,000 0,0251713 0,03347092 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,0251713 0,03344679 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,0251713 0,03342269 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,0251713 0,03339863 ! cellular component disassembly GO:0022411 26 25 0,000 0,0251713 0,0333746 ! endosome transport GO:0016197 25 25 0,000 0,0251713 0,03335061 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,0251713 0,03332665 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,0251713 0,03330273 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,0251713 0,03327884 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,0251713 0,03325498 ! excretion GO:0007588 25 25 0,000 0,0251713 0,03323116 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,0251713 0,03320737 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,0251713 0,03318362 ! gastrulation GO:0007369 25 25 0,000 0,0251713 0,0331599 ! heart morphogenesis GO:0003007 25 25 0,000 0,0251713 0,03313621 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,0251713 0,03311256 ! regulation of endocytosis GO:0030100 25 25 0,000 0,0251713 0,03308894 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,0251713 0,03306536 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,0251713 0,03304181 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,0251713 0,03301829 ! positive regulation of binding GO:0051099 27 26 0,000 0,02616674 0,03429965 ! positive regulation of defense response GO:0031349 26 26 0,000 0,02616674 0,03427527 ! glycolysis GO:0006096 26 26 0,000 0,02616674 0,03425093 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,02616674 0,03422662 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,02616674 0,03420235 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,02616674 0,03417811 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,02616674 0,0341539 ! cellular defense response GO:0006968 26 26 0,000 0,02616674 0,03412973 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,02616674 0,03410559 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,02616674 0,03408149 ! double-strand break repair GO:0006302 27 26 0,000 0,02616674 0,03405742 ! regulation of protein secretion GO:0050708 26 26 0,000 0,02616674 0,03403339 ! germ cell development GO:0007281 27 26 0,000 0,02616674 0,03400939 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,02616674 0,03398542 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,02616674 0,03396149 ! response to insulin stimulus GO:0032868 28 26 0,000 0,02616674 0,03393759 ! synapse organization GO:0050808 26 26 0,000 0,02616674 0,03391372 ! chloride transport GO:0006821 27 27 0,000 0,02716132 0,03517802 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,02716132 0,03515331 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,02716132 0,03512864 ! learning or memory GO:0007611 28 27 0,000 0,02716132 0,03510401 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,02716132 0,03507941 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,02716132 0,03505484 ! peptide metabolic process GO:0006518 29 27 0,000 0,02716132 0,03503031 ! activation of caspase activity GO:0006919 27 27 0,000 0,02716132 0,03500582 ! mesenchymal cell development GO:0014031 29 27 0,000 0,02716132 0,03498135 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! defense response to bacterium GO:0042742 27 27 0,000 0,02716132 0,03495692 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,02716132 0,03493253 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,02716132 0,03490817 ! cell growth GO:0016049 27 27 0,000 0,02716132 0,03488384 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,02815503 0,0361349 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,02815503 0,03610975 ! carbohydrate transport GO:0008643 28 28 0,000 0,02815503 0,03608464 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,02815503 0,03605957 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,02815503 0,03603453 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,02815503 0,03600952 ! histone modification GO:0016570 28 28 0,000 0,02815503 0,03598455 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,02815503 0,03595961 ! developmental growth GO:0048589 28 28 0,000 0,02815503 0,03593471 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,02815503 0,03590984 ! cartilage development GO:0051216 29 28 0,000 0,02815503 0,035885 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,02914786 0,03712475 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,02914786 0,03709911 ! viral reproductive process GO:0022415 29 29 0,000 0,02914786 0,03707351 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,02914786 0,03704794 ! leukocyte migration GO:0050900 30 29 0,000 0,02914786 0,03702241 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,02914786 0,03699691 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,02914786 0,03697145 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,02914786 0,03694602 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,02914786 0,03692063 ! tRNA processing GO:0008033 29 29 0,000 0,02914786 0,03689527 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,02914786 0,03686995 ! covalent chromatin modification GO:0016569 29 29 0,000 0,02914786 0,03684466 ! adult behavior GO:0030534 30 29 0,000 0,02914786 0,03681941 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,02914786 0,03679419 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,02914786 0,036769 ! response to UV GO:0009411 29 29 0,000 0,02914786 0,03674385 ! transition metal ion transport GO:0000041 31 30 0,000 0,03013983 0,03796836 ! RNA catabolic process GO:0006401 30 30 0,000 0,03013983 0,03794242 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,03013983 0,03791653 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,03013983 0,03789066 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,03013983 0,03786483 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,03013983 0,03783904 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,03013983 0,03781328 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,03013983 0,03778756 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,03013983 0,03776187 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,03013983 0,03773622 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,03013983 0,0377106 ! response to temperature stimulus GO:0009266 30 30 0,000 0,03013983 0,03768501 ! regulation of ossification GO:0030278 30 30 0,000 0,03013983 0,03765946 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,03013983 0,03763395 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,03013983 0,03760847 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,03013983 0,03758302 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,03013983 0,03755761 ! vesicle organization GO:0016050 30 30 0,000 0,03013983 0,03753224 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,03013983 0,03750689 ! establishment of organelle localization GO:0051656 31 30 0,000 0,03013983 0,03748159 ! regulation of translational initiation GO:0006446 31 31 0,000 0,03113093 0,038688 ! membrane fusion GO:0006944 31 31 0,000 0,03113093 0,03866193 ! B cell activation GO:0042113 31 31 0,000 0,03113093 0,03863589 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,03113093 0,03860989 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,03113093 0,03858393 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,03113093 0,038558 ! ion transmembrane transport GO:0034220 31 31 0,000 0,03113093 0,0385321 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,03113093 0,03850624 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,03113093 0,03848042 ! digestion GO:0007586 31 31 0,000 0,03113093 0,03845463 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,03113093 0,03842887 ! regulation of DNA replication GO:0006275 32 31 0,000 0,03113093 0,03840315 ! regulation of heart contraction GO:0008016 31 31 0,000 0,03113093 0,03837746 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,03113093 0,03835181 ! camera-type eye development GO:0043010 31 31 0,000 0,03113093 0,03832619 ! extracellular matrix organization GO:0030198 31 31 0,000 0,03113093 0,0383006 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,03113093 0,03827505 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,03113093 0,03824954 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,03113093 0,03822405 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,03212116 0,03941365 ! cell redox homeostasis GO:0045454 32 32 0,000 0,03212116 0,03938742 ! glucose catabolic process GO:0006007 32 32 0,000 0,03212116 0,03936123 ! lipid modification GO:0030258 32 32 0,000 0,03212116 0,03933508 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,03212116 0,03930896 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,03212116 0,03928288 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,03212116 0,03925683 ! cell maturation GO:0048469 32 32 0,000 0,03212116 0,03923081 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,03212116 0,03920483 ! nuclear export GO:0051168 32 32 0,000 0,03212116 0,03917889 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,03212116 0,03915297 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,03212116 0,0391271 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,03212116 0,03910125 ! negative regulation of cell size GO:0045792 33 33 0,000 0,03311052 0,040279 ! amino acid transport GO:0006865 33 33 0,000 0,03311052 0,04025243 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,03311052 0,0402259 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,03311052 0,0401994 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,03311052 0,04017294 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,03311052 0,04014651 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,03311052 0,04012011 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,03311052 0,04009375 ! regulation of actin filament length GO:0030832 34 34 0,000 0,03409902 0,04126362 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,03409902 0,04123654 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,03409902 0,0412095 ! response to metal ion GO:0010038 34 34 0,000 0,03409902 0,04118249 ! muscle cell differentiation GO:0042692 35 34 0,000 0,03409902 0,04115553 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,03409902 0,04112859 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,03409902 0,04110169 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,03409902 0,04107483 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,03409902 0,041048 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,03409902 0,04102121 ! secondary metabolic process GO:0019748 34 34 0,000 0,03409902 0,04099445 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,03409902 0,04096772 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,03409902 0,04094103 ! viral reproduction GO:0016032 34 34 0,000 0,03409902 0,04091438 ! detection of stimulus GO:0051606 36 34 0,000 0,03409902 0,04088776 ! acute inflammatory response GO:0002526 35 35 0,000 0,03508665 0,04204466 ! regulation of cellular component size GO:0032535 35 35 0,000 0,03508665 0,04201734 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,03508665 0,04199006 ! mesoderm development GO:0007498 35 35 0,000 0,03508665 0,04196281 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,03508665 0,04193559 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,03508665 0,04190842 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,03508665 0,04188127 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,03508665 0,04185417 ! inorganic anion transport GO:0015698 35 35 0,000 0,03508665 0,04182709 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,03508665 0,04180006 ! regulation of immune effector process GO:0002697 35 35 0,000 0,03508665 0,04177305 ! hydrogen transport GO:0006818 36 36 0,000 0,03607341 0,04292014 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,03607341 0,04289245 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,03607341 0,04286479 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,03607341 0,04283717 ! regulation of mitosis GO:0007088 37 36 0,000 0,03607341 0,04280959 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,03607341 0,04278204 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,03607341 0,04275453 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,03607341 0,04272705 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,03607341 0,04269961 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,03607341 0,0426722 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,03607341 0,04264483 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,03607341 0,04261749 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,03607341 0,04259019 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,03607341 0,04256293 ! gonad development GO:0008406 36 36 0,000 0,03607341 0,0425357 ! regulation of lipase activity GO:0060191 36 36 0,000 0,03607341 0,0425085 ! activation of immune response GO:0002253 36 36 0,000 0,03607341 0,04248134 ! coagulation GO:0050817 39 36 0,000 0,03607341 0,04245421 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,03705931 0,04358666 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,03705931 0,04355887 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,03705931 0,0435311 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 0,000 0,03705931 0,04350338 ! lung development GO:0030324 38 37 0,000 0,03705931 0,04347569 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,03705931 0,04344803 ! eye development GO:0001654 37 37 0,000 0,03705931 0,04342041 ! negative regulation of growth GO:0045926 37 37 0,000 0,03705931 0,04339282 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,03705931 0,04336527 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,03705931 0,04333775 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,03705931 0,04331027 ! adaptive immune response GO:0002250 37 37 0,000 0,03705931 0,04328283 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,03804434 0,04440514 ! neurotransmitter transport GO:0006836 40 38 0,000 0,03804434 0,04437704 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,03804434 0,04434897 ! exocytosis GO:0006887 40 38 0,000 0,03804434 0,04432093 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,03804434 0,04429294 ! chromosome segregation GO:0007059 38 38 0,000 0,03804434 0,04426497 ! hexose catabolic process GO:0019320 38 38 0,000 0,03804434 0,04423705 ! RNA elongation GO:0006354 38 38 0,000 0,03804434 0,04420915 ! meiotic cell cycle GO:0051321 38 38 0,000 0,03804434 0,0441813 ! axon guidance GO:0007411 39 38 0,000 0,03804434 0,04415348 ! regulation of neurological system process GO:0031644 38 38 0,000 0,03804434 0,04412569 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,03804434 0,04409794 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,03804434 0,04407022 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,03902851 0,04518187 ! hemostasis GO:0007599 42 39 0,000 0,03902851 0,04515351 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,03902851 0,04512518 ! respiratory tube development GO:0030323 40 39 0,000 0,03902851 0,04509689 ! response to unfolded protein GO:0006986 39 39 0,000 0,03902851 0,04506864 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,03902851 0,04504042 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,03902851 0,04501223 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,03902851 0,04498408 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,03902851 0,04495596 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,03902851 0,04492788 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,03902851 0,04489984 ! respiratory system development GO:0060541 40 39 0,000 0,03902851 0,04487183 ! developmental maturation GO:0021700 39 39 0,000 0,03902851 0,04484386 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,03902851 0,04481591 ! limb development GO:0060173 39 39 0,000 0,03902851 0,04478801 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,03902851 0,04476014 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,03902851 0,0447323 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,04001182 0,04583081 ! DNA catabolic process GO:0006308 41 40 0,000 0,04001182 0,04580235 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,04001182 0,04577392 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,04001182 0,04574552 ! organelle localization GO:0051640 41 40 0,000 0,04001182 0,04571716 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,04099426 0,04681067 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,04099426 0,04678169 ! amine catabolic process GO:0009310 42 41 0,000 0,04099426 0,04675274 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,04099426 0,04672382 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,04099426 0,04669495 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,04099426 0,0466661 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,04099426 0,0466373 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,04099426 0,04660853 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,04197584 0,04769512 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,04197584 0,04766573 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,04197584 0,04763638 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,04197584 0,04760706 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,04197584 0,04757778 ! protein ubiquitination GO:0016567 43 42 0,000 0,04197584 0,04754854 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,04197584 0,04751934 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,04197584 0,04749016 ! forebrain development GO:0030900 43 42 0,000 0,04197584 0,04746103 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,04197584 0,04743193 ! reproductive structure development GO:0048608 43 43 0,000 0,04295656 0,04851038 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,04295656 0,04848068 ! alcohol catabolic process GO:0046164 43 43 0,000 0,04295656 0,04845101 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,04295656 0,04842137 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,04295656 0,04839178 ! humoral immune response GO:0006959 44 44 0,000 0,04393642 0,04946538 ! mRNA transport GO:0051028 44 44 0,000 0,04393642 0,04943518 ! protein import into nucleus GO:0006606 44 44 0,000 0,04393642 0,04940502 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,04393642 0,0493749 ! vitamin metabolic process GO:0006766 44 44 0,000 0,04393642 0,04934481 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,04393642 0,04931476 ! amine biosynthetic process GO:0009309 46 45 0,000 0,04491542 0,05038291 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,04491542 0,05035227 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,04491542 0,05032166 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,04491542 0,05029109 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,04491542 0,05026055 ! nuclear import GO:0051170 45 45 0,000 0,04491542 0,05023005 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,04491542 0,05019959 ! protein processing GO:0016485 45 45 0,000 0,04491542 0,05016917 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,04589356 0,05123067 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,04589356 0,05119966 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,04589356 0,05116869 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,04589356 0,05113775 ! regulation of membrane potential GO:0042391 46 46 0,000 0,04589356 0,05110685 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,04687085 0,05216363 ! regulation of blood pressure GO:0008217 48 47 0,000 0,04687085 0,05213215 ! sex differentiation GO:0007548 47 47 0,000 0,04687085 0,05210071 ! amine transport GO:0015837 47 47 0,000 0,04687085 0,0520693 ! rhythmic process GO:0048511 47 47 0,000 0,04687085 0,05203793 ! regulation of catabolic process GO:0009894 48 47 0,000 0,04687085 0,0520066 ! calcium ion transport GO:0006816 48 48 0,000 0,04784727 0,05305807 ! actin filament organization GO:0007015 50 48 0,000 0,04784727 0,05302617 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,04784727 0,0529943 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,04784727 0,05296247 ! protein localization in nucleus GO:0034504 48 48 0,000 0,04784727 0,05293068 ! DNA recombination GO:0006310 48 48 0,000 0,04784727 0,05289893 ! leukocyte differentiation GO:0002521 50 49 0,000 0,04882284 0,05394514 ! ossification GO:0001503 50 49 0,000 0,04882284 0,05391281 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 0,000 0,04882284 0,05388053 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,04882284 0,05384829 ! divalent metal ion transport GO:0070838 49 49 0,000 0,04882284 0,05381608 ! response to nutrient GO:0007584 49 49 0,000 0,04882284 0,05378391 ! response to bacterium GO:0009617 50 49 0,000 0,04882284 0,05375178 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,04882284 0,05371969 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,04882284 0,05368764 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,04979755 0,05472682 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,04979755 0,05469421 ! chromatin assembly GO:0031497 50 50 0,000 0,04979755 0,05466163 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,04979755 0,05462909 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,04979755 0,0545966 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,04979755 0,05456414 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,04979755 0,05453172 ! transcription initiation GO:0006352 50 50 0,000 0,04979755 0,05449933 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,04979755 0,05446699 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,04979755 0,05443468 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,0507714 0,05546632 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,0507714 0,05543346 ! positive regulation of immune response GO:0050778 51 51 0,000 0,0507714 0,05540064 ! rRNA metabolic process GO:0016072 51 51 0,000 0,0507714 0,05536786 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,0507714 0,05533512 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,0507714 0,05530242 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,0507714 0,05526975 ! protein maturation GO:0051604 51 51 0,000 0,0507714 0,05523712 ! RNA localization GO:0006403 52 52 0,000 0,0517444 0,05626249 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,0517444 0,05622932 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,0517444 0,05619618 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,0517444 0,05616309 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,0517444 0,05613003 ! response to light stimulus GO:0009416 53 52 0,000 0,0517444 0,05609701 ! sodium ion transport GO:0006814 53 53 0,000 0,05271654 0,05711733 ! tRNA metabolic process GO:0006399 53 53 0,000 0,05271654 0,05708377 ! response to hypoxia GO:0001666 53 53 0,000 0,05271654 0,05705025 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,05271654 0,05701677 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,05271654 0,05698333 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,05271654 0,05694993 ! regulation of T cell activation GO:0050863 53 53 0,000 0,05271654 0,05691657 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,05368783 0,0579313 ! response to oxygen levels GO:0070482 55 54 0,000 0,05368783 0,05789741 ! response to virus GO:0009615 54 54 0,000 0,05368783 0,05786355 ! hormone metabolic process GO:0042445 55 54 0,000 0,05368783 0,05782973 ! sulfur metabolic process GO:0006790 55 54 0,000 0,05368783 0,05779595 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,05368783 0,05776221 ! nucleosome organization GO:0034728 55 55 0,000 0,05465826 0,05877198 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,05465826 0,05873771 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,05465826 0,05870348 ! in utero embryonic development GO:0001701 55 55 0,000 0,05465826 0,05866929 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,05465826 0,05863514 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,05465826 0,05860103 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,05562784 0,05960588 ! reproductive developmental process GO:0003006 56 56 0,000 0,05562784 0,05957125 ! extracellular structure organization GO:0043062 56 56 0,000 0,05562784 0,05953665 ! ATP metabolic process GO:0046034 57 57 0,000 0,05659657 0,06053829 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,05659657 0,06050318 ! innate immune response GO:0045087 58 58 0,000 0,05756445 0,06150219 ! dephosphorylation GO:0016311 60 59 0,000 0,05853147 0,06249914 ! carboxylic acid transport GO:0046942 59 59 0,000 0,05853147 0,06246295 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,05853147 0,0624268 ! sterol metabolic process GO:0016125 59 59 0,000 0,05853147 0,06239069 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,05853147 0,06235463 ! protein localization in organelle GO:0033365 59 59 0,000 0,05853147 0,06231861 ! immune effector process GO:0002252 59 59 0,000 0,05853147 0,06228263 ! potassium ion transport GO:0006813 60 60 0,000 0,05949765 0,06327419 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,05949765 0,0632377 ! protein polymerization GO:0051258 65 60 0,000 0,05949765 0,06320125 ! cellular respiration GO:0045333 62 61 0,000 0,06046297 0,06418967 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,06046297 0,06415271 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,06046297 0,0641158 ! lipid transport GO:0006869 62 62 0,000 0,06142745 0,06510109 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,06142745 0,06506367 ! axonogenesis GO:0007409 66 62 0,000 0,06142745 0,0650263 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,06142745 0,06498897 ! protein import GO:0017038 62 62 0,000 0,06142745 0,06495169 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,06142745 0,06491444 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,06142745 0,06487724 ! regulation of secretion GO:0051046 65 63 0,000 0,06239108 0,06585725 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,06239108 0,06581955 ! glucose metabolic process GO:0006006 63 63 0,000 0,06239108 0,0657819 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,06239108 0,06574429 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,06239108 0,06570672 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,06335386 0,06668256 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,06335386 0,0666445 ! angiogenesis GO:0001525 65 64 0,000 0,06335386 0,06660648 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,06335386 0,0665685 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,06335386 0,06653057 ! anion transport GO:0006820 65 65 0,000 0,06431579 0,06750228 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,06431579 0,06746386 ! regulation of hormone levels GO:0010817 66 65 0,000 0,06431579 0,06742548 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,06527687 0,06839413 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,06527687 0,06835527 ! DNA packaging GO:0006323 66 66 0,000 0,06527687 0,06831645 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,06527687 0,06827768 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,06527687 0,06823895 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,06623711 0,06920351 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,06623711 0,0691643 ! muscle contraction GO:0006936 67 67 0,000 0,06623711 0,06912514 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,06623711 0,06908602 ! response to radiation GO:0009314 70 68 0,000 0,0671965 0,07004703 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,0671965 0,07000743 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,0671965 0,06996788 ! regulation of translation GO:0006417 69 69 0,000 0,06815505 0,07092589 ! response to nutrient levels GO:0031667 69 69 0,000 0,06815505 0,07088587 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,06815505 0,07084589 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,06815505 0,07080595 ! positive regulation of transport GO:0051050 71 70 0,000 0,06911275 0,07176045 ! cell part morphogenesis GO:0032990 75 70 0,000 0,06911275 0,07172005 ! wound healing GO:0042060 74 70 0,000 0,06911275 0,07167969 ! growth GO:0040007 70 70 0,000 0,06911275 0,07163937 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,06911275 0,0715991 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,07006961 0,0725496 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,07006961 0,07250887 ! regulation of cell migration GO:0030334 71 71 0,000 0,07006961 0,07246818 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,07006961 0,07242753 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,07006961 0,07238694 ! regulation of cell activation GO:0050865 71 71 0,000 0,07006961 0,07234638 ! secretion by cell GO:0032940 75 72 0,000 0,07102563 0,0732924 ! muscle system process GO:0003012 72 72 0,000 0,07102563 0,07325139 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,07102563 0,07321042 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,07102563 0,0731695 ! regulation of cytokine production GO:0001817 72 72 0,000 0,07102563 0,07312862 ! electron transport chain GO:0022900 75 74 0,000 0,07293513 0,07505273 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,07293513 0,07501085 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,07388862 0,0759491 ! response to oxidative stress GO:0006979 76 75 0,000 0,07388862 0,07590676 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,07388862 0,07586447 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,07484127 0,07679981 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,07579308 0,07773325 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,07579308 0,07769002 ! microtubule-based movement GO:0007018 82 78 0,000 0,07674405 0,07862106 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,07674405 0,07857738 ! metal ion homeostasis GO:0055065 78 78 0,000 0,07674405 0,07853375 ! regulation of immune response GO:0050776 78 78 0,000 0,07674405 0,07849017 ! regulation of locomotion GO:0040012 79 79 0,000 0,07769418 0,07941785 ! nuclear transport GO:0051169 79 79 0,000 0,07769418 0,07937382 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 0,000 0,07769418 0,07932985 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,07864347 0,08025466 ! neuron projection development GO:0031175 85 80 0,000 0,07864347 0,08021025 ! lymphocyte activation GO:0046649 82 81 0,000 0,07959193 0,0811327 ! lipid catabolic process GO:0016042 82 81 0,000 0,07959193 0,08108785 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,08148633 0,08297199 ! ncRNA processing GO:0034470 83 83 0,000 0,08148633 0,08292618 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,08148633 0,08288041 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,08243228 0,0837963 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,08337739 0,08471032 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,08337739 0,08466365 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,08337739 0,08461703 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,08432166 0,08552825 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,08432166 0,0854812 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,08432166 0,08543421 ! heart development GO:0007507 90 87 0,000 0,08526511 0,08634263 ! male gamete generation GO:0048232 90 88 0,000 0,08620772 0,08724921 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,08620772 0,08720133 ! chemotaxis GO:0006935 90 89 0,000 0,08714949 0,0881056 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,08714949 0,0880573 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,08809044 0,08895927 ! brain development GO:0007420 91 90 0,000 0,08809044 0,08891056 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,08903055 0,08981024 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,08903055 0,08976111 ! visual perception GO:0007601 93 92 0,000 0,08996983 0,0906585 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,08996983 0,09060896 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,08996983 0,09055948 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,08996983 0,09051004 ! blood vessel development GO:0001568 95 94 0,000 0,09184591 0,09234697 ! cofactor metabolic process GO:0051186 95 94 0,000 0,09184591 0,09229662 ! vasculature development GO:0001944 97 96 0,000 0,09371866 0,09412725 ! endocytosis GO:0006897 99 98 0,000 0,09558811 0,09595255 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,09558811 0,09590032 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,09558811 0,09584814 ! blood circulation GO:0008015 99 98 0,000 0,09558811 0,09579602 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,09558811 0,09574396 ! response to hormone stimulus GO:0009725 102 100 0,000 0,09745425 0,09756012 ! response to other organism GO:0051707 101 100 0,000 0,09745425 0,09750716 ! hemopoiesis GO:0030097 104 100 0,000 0,09745425 0,09745425