pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/3308-4-real-Loi_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 7,834E-12 1,885E-08 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 1,752E-08 2,108E-05 ! interphase GO:0051325 213 98 4,000 2,05E-08 1,644E-05 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 6,946E-08 4,178E-05 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 2,000 7,518E-07 3,618E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 1,297E-06 5,202E-04 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 2,000 4,001E-06 1,375E-03 ! muscle cell migration GO:0014812 8 5 1,000 7,155E-06 2,152E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 7,912E-06 2,115E-03 ! response to UV GO:0009411 104 53 2,000 1,3E-05 3,128E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2E-05 4,375E-03 ! chaperone-mediated protein complex assembly GO:0051131 13 8 1,000 2E-05 4,01E-03 ! outer mitochondrial membrane organization GO:0007008 16 8 1,000 2E-05 3,702E-03 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! keratinocyte proliferation GO:0043616 14 9 1,000 2,57E-05 4,417E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 2,57E-05 4,123E-03 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 2,57E-05 3,865E-03 ! induction of an organ GO:0001759 14 9 1,000 2,57E-05 3,638E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 2,638E-05 3,525E-03 ! negative regulation of kinase activity GO:0033673 131 68 2,000 2,758E-05 3,492E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 2,758E-05 3,317E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 2,881E-05 3,301E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 3,211E-05 3,512E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 3,211E-05 3,359E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 3,274E-05 3,282E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 3,274E-05 3,151E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 3,274E-05 3,03E-03 ! thyroid gland development GO:0030878 26 11 1,000 3,923E-05 3,496E-03 ! thymus development GO:0048538 27 11 1,000 3,923E-05 3,371E-03 ! developmental induction GO:0031128 19 11 1,000 3,923E-05 3,255E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! positive regulation of ligase activity GO:0051351 124 77 2,000 4,004E-05 3,212E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 4,324E-05 3,356E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 4,705E-05 3,537E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 4,705E-05 3,43E-03 ! regulation of ligase activity GO:0051340 142 84 2,000 5,195E-05 3,676E-03 ! response to unfolded protein GO:0006986 131 85 2,000 5,382E-05 3,7E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 5,557E-05 3,714E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 5,557E-05 3,614E-03 ! mitochondrion organization GO:0007005 148 86 2,000 5,574E-05 3,529E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 6,48E-05 3,998E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 6,48E-05 3,898E-03 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 6,48E-05 3,803E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 6,48E-05 3,712E-03 ! response to protein stimulus GO:0051789 149 91 2,000 6,597E-05 3,691E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 7,039E-05 3,849E-03 GO:0010498|proteasomal protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 1,000 7,473E-05 3,996E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 8,536E-05 4,465E-03 ! cell cycle arrest GO:0007050 213 100 2,000 8,736E-05 4,472E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 9,669E-05 4,847E-03 ! skin development GO:0043588 36 19 1,000 1,214E-04 5,963E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,214E-04 5,844E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,349E-04 6,363E-03 ! axis specification GO:0009798 38 21 1,000 1,49E-04 6,893E-03 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 1,49E-04 6,763E-03 ! ureteric bud development GO:0001657 43 22 1,000 1,638E-04 7,298E-03 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,638E-04 7,165E-03 ! activation of JUN kinase activity GO:0007257 42 22 1,000 1,638E-04 7,037E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,955E-04 8,252E-03 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,955E-04 8,11E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,124E-04 8,661E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,124E-04 8,517E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 2,3E-04 9,07E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,3E-04 8,924E-03 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 2,3E-04 8,782E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 2,482E-04 9,332E-03 ! fat cell differentiation GO:0045444 50 27 1,000 2,482E-04 9,188E-03 ! mitochondrial membrane organization GO:0007006 57 27 1,000 2,482E-04 9,049E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,672E-04 9,594E-03 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 2,672E-04 9,453E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 2,868E-04 0,01000112 ! regulation of B cell activation GO:0050864 50 30 1,000 3,071E-04 0,0105568 ! inner ear morphogenesis GO:0042472 47 31 1,000 3,281E-04 0,01112001 ! metanephros development GO:0001656 74 32 1,000 3,498E-04 0,0116904 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 3,498E-04 0,01153026 ! cell fate specification GO:0001708 52 33 1,000 3,722E-04 0,01210185 ! negative regulation of protein transport GO:0051224 69 33 1,000 3,722E-04 0,01194049 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 4,19E-04 0,01326453 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 4,19E-04 0,01309227 ! maintenance of protein location in cell GO:0032507 86 36 1,000 4,434E-04 0,01367742 ! negative regulation of DNA binding GO:0043392 68 37 1,000 4,685E-04 0,01426839 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 4,943E-04 0,01486492 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! ear morphogenesis GO:0042471 60 39 1,000 5,207E-04 0,01546678 ! negative regulation of binding GO:0051100 72 40 1,000 5,478E-04 0,01607375 ! maintenance of protein location GO:0045185 91 40 1,000 5,478E-04 0,01588009 ! keratinocyte differentiation GO:0030216 62 41 1,000 5,756E-04 0,01648696 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 5,756E-04 0,01629299 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 6,041E-04 0,01689975 ! epithelial cell differentiation GO:0030855 79 43 1,000 6,332E-04 0,01751111 ! maintenance of location in cell GO:0051651 97 44 1,000 6,63E-04 0,01812688 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 6,935E-04 0,0187469 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 7,246E-04 0,01937099 ! epidermal cell differentiation GO:0009913 68 46 1,000 7,246E-04 0,01915812 ! response to calcium ion GO:0051592 81 47 1,000 7,564E-04 0,0197816 ! JNK cascade GO:0007254 91 47 1,000 7,564E-04 0,01956889 ! regulation of JNK cascade GO:0046328 94 47 1,000 7,564E-04 0,01936071 ! positive regulation of cell cycle GO:0045787 89 48 1,000 7,889E-04 0,01997922 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 7,889E-04 0,01977111 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 7,889E-04 0,01956728 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 8,22E-04 0,02018106 ! endocrine system development GO:0035270 104 49 1,000 8,22E-04 0,01997721 ! inner ear development GO:0048839 79 50 1,000 8,558E-04 0,02059058 ! embryonic skeletal system development GO:0048706 85 51 1,000 8,903E-04 0,02120757 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 8,903E-04 0,02099965 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 1,000 8,903E-04 0,02079577 ! positive regulation of growth GO:0045927 90 52 1,000 9,254E-04 0,02140829 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 9,254E-04 0,0212044 ! skeletal muscle fiber development GO:0048741 111 56 1,000 1,072E-03 0,02434251 ! muscle fiber development GO:0048747 112 57 1,000 1,111E-03 0,02497867 ! regulation of intracellular transport GO:0032386 101 57 1,000 1,111E-03 0,02474739 ! maintenance of location GO:0051235 118 57 1,000 1,111E-03 0,02452035 ! skeletal system morphogenesis GO:0048705 105 59 1,000 1,19E-03 0,02602059 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 1,23E-03 0,02666121 ! kidney development GO:0001822 122 60 1,000 1,23E-03 0,02642316 ! ear development GO:0043583 103 62 1,000 1,313E-03 0,02795002 ! regulation of cellular response to stress GO:0080135 128 67 1,000 1,531E-03 0,03230739 ! negative regulation of cell growth GO:0030308 132 67 1,000 1,531E-03 0,03202646 ! activation of MAPK activity GO:0000187 115 67 1,000 1,531E-03 0,03175037 ! negative regulation of cell size GO:0045792 134 69 1,000 1,623E-03 0,03336567 ! urogenital system development GO:0001655 137 69 1,000 1,623E-03 0,03308291 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 1,717E-03 0,03471178 ! regulation of caspase activity GO:0043281 122 72 1,000 1,765E-03 0,03538726 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,765E-03 0,0350948 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 1,863E-03 0,03674276 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 2,015E-03 0,03941722 ! regulation of peptidase activity GO:0052547 134 79 1,000 2,12E-03 0,04112696 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 2,12E-03 0,04079795 ! response to metal ion GO:0010038 140 80 1,000 2,173E-03 0,04148997 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 2,227E-03 0,04218304 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of neuron differentiation GO:0045664 167 81 1,000 2,227E-03 0,04185348 ! negative regulation of transport GO:0051051 153 84 1,000 2,392E-03 0,04461122 ! negative regulation of growth GO:0045926 155 84 1,000 2,392E-03 0,04426806 ! positive regulation of cell activation GO:0050867 145 85 1,000 2,448E-03 0,04496487 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 2,505E-03 0,04566253 ! tube morphogenesis GO:0035239 176 86 1,000 2,505E-03 0,0453192 ! regulation of protein transport GO:0051223 154 87 1,000 2,563E-03 0,046015 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 1,000 2,621E-03 0,04671159 ! regulation of DNA binding GO:0051101 155 88 1,000 2,621E-03 0,04636813 ! gland development GO:0048732 206 88 1,000 2,621E-03 0,04602967 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 2,921E-03 0,05093291 ! regulation of protein localization GO:0032880 176 97 1,000 3,173E-03 0,05491808 ! skeletal muscle tissue development GO:0007519 186 99 1,000 3,302E-03 0,05674932 GO:0060538|skeletal muscle organ development, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 4,309E-03 0,07353381 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 4,309E-03 0,07301597 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,309E-03 0,07250537 ! positive regulation of helicase activity GO:0051096 11 5 0,000 4,309E-03 0,07200186 ! neuron fate determination GO:0048664 7 5 0,000 4,309E-03 0,0715053 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,309E-03 0,07101553 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 4,309E-03 0,07053243 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 4,309E-03 0,07005586 ! polyol transport GO:0015791 12 5 0,000 4,309E-03 0,06958569 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 4,309E-03 0,06912179 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,309E-03 0,06866403 ! response to superoxide GO:0000303 10 5 0,000 4,309E-03 0,06821229 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,309E-03 0,06776646 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 4,309E-03 0,06732641 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 4,309E-03 0,06689205 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,309E-03 0,06646326 ! female meiosis GO:0007143 7 5 0,000 4,309E-03 0,06603992 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 4,309E-03 0,06562195 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,309E-03 0,06520923 ! cobalt ion transport GO:0006824 11 5 0,000 4,309E-03 0,06480167 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 4,309E-03 0,06439918 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 4,309E-03 0,06400165 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 4,309E-03 0,063609 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,309E-03 0,06322115 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,309E-03 0,06283799 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 4,309E-03 0,06245944 ! embryonic camera-type eye development GO:0031076 10 5 0,000 4,309E-03 0,06208544 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,309E-03 0,06171588 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 4,309E-03 0,0613507 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 4,309E-03 0,06098981 ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,309E-03 0,06063315 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,309E-03 0,06028063 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,309E-03 0,05993218 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 4,309E-03 0,05958775 ! negative chemotaxis GO:0050919 14 5 0,000 4,309E-03 0,05924724 ! positive regulation of histone modification GO:0031058 5 5 0,000 4,309E-03 0,05891061 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,309E-03 0,05857778 ! sensory perception of bitter taste GO:0050913 7 5 0,000 4,309E-03 0,0582487 ! behavioral response to pain GO:0048266 9 5 0,000 4,309E-03 0,05792328 ! clathrin coat assembly GO:0048268 14 5 0,000 4,309E-03 0,05760149 ! Notch receptor processing GO:0007220 8 5 0,000 4,309E-03 0,05728325 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,309E-03 0,0569685 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 4,309E-03 0,0566572 ! micturition GO:0060073 9 5 0,000 4,309E-03 0,05634928 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,309E-03 0,05604469 ! copulation GO:0007620 9 5 0,000 4,309E-03 0,05574338 ! glial cell fate commitment GO:0021781 13 5 0,000 4,309E-03 0,05544528 ! protein maturation by protein folding GO:0022417 13 5 0,000 4,309E-03 0,05515036 ! spermidine metabolic process GO:0008216 7 5 0,000 4,309E-03 0,05485856 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,309E-03 0,05456983 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,309E-03 0,05428412 ! apoptotic cell clearance GO:0043277 20 5 0,000 4,309E-03 0,05400139 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,309E-03 0,05372159 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,309E-03 0,05344468 ! grooming behavior GO:0007625 6 5 0,000 4,309E-03 0,0531706 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,309E-03 0,05289933 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 4,309E-03 0,0526308 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,309E-03 0,05236499 ! response to protozoan GO:0001562 10 5 0,000 4,309E-03 0,05210185 ! positive regulation of glycolysis GO:0045821 14 5 0,000 4,309E-03 0,05184134 ! lymph vessel development GO:0001945 10 5 0,000 4,309E-03 0,05158342 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 4,309E-03 0,05132806 ! endochondral ossification GO:0001958 16 5 0,000 4,309E-03 0,05107521 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,309E-03 0,05082484 ! parathyroid gland development GO:0060017 13 5 0,000 4,309E-03 0,05057692 ! anagen GO:0042640 6 5 0,000 4,309E-03 0,0503314 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,309E-03 0,05008825 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,309E-03 0,04984744 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 4,309E-03 0,04960894 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 4,309E-03 0,0493727 ! dorsal spinal cord development GO:0021516 7 5 0,000 4,309E-03 0,04913871 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 4,309E-03 0,04890692 ! sphingoid catabolic process GO:0046521 6 5 0,000 4,309E-03 0,04867731 ! skeletal myofibril assembly GO:0014866 10 5 0,000 4,309E-03 0,04844985 ! smooth muscle tissue development GO:0048745 28 5 0,000 4,309E-03 0,0482245 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,309E-03 0,04800124 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,309E-03 0,04778004 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,309E-03 0,04756086 ! cardiac muscle fiber development GO:0048739 10 5 0,000 4,309E-03 0,04734369 ! transepithelial chloride transport GO:0030321 9 5 0,000 4,309E-03 0,04712849 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,309E-03 0,04691524 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 4,309E-03 0,04670391 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 4,309E-03 0,04649447 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,309E-03 0,04628691 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,309E-03 0,04608119 ! histidine catabolic process GO:0006548 6 5 0,000 4,309E-03 0,04587729 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 4,309E-03 0,04567519 ! microvillus organization GO:0032528 7 5 0,000 4,309E-03 0,04547486 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 4,309E-03 0,04527628 ! L-serine biosynthetic process GO:0006564 6 5 0,000 4,309E-03 0,04507943 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,309E-03 0,04488428 ! tryptophan metabolic process GO:0006568 9 5 0,000 4,309E-03 0,04469081 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 4,309E-03 0,044499 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 4,309E-03 0,04430884 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 4,309E-03 0,04412029 ! polyol catabolic process GO:0046174 7 5 0,000 4,309E-03 0,04393334 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 4,309E-03 0,04374797 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 4,309E-03 0,04356415 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,309E-03 0,04338187 ! mitochondrial fission GO:0000266 8 5 0,000 4,309E-03 0,04320112 ! sister chromatid cohesion GO:0007062 12 5 0,000 4,309E-03 0,04302186 ! mRNA transcription GO:0009299 9 5 0,000 4,309E-03 0,04284408 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 4,309E-03 0,04266777 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 4,309E-03 0,0424929 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 4,309E-03 0,04231946 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 4,309E-03 0,04214743 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,309E-03 0,04197679 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,309E-03 0,04180753 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,309E-03 0,04163963 ! response to food GO:0032094 6 5 0,000 4,309E-03 0,04147307 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,309E-03 0,04130784 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,309E-03 0,04114392 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 4,309E-03 0,0409813 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,309E-03 0,04081995 ! paraxial mesoderm development GO:0048339 14 5 0,000 4,309E-03 0,04065987 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 4,309E-03 0,04050105 ! forebrain neuron development GO:0021884 13 5 0,000 4,309E-03 0,04034345 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,309E-03 0,04018708 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 4,309E-03 0,04003192 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,309E-03 0,03987795 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,309E-03 0,03972516 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,309E-03 0,03957354 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 4,309E-03 0,03942307 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,309E-03 0,03927374 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 4,309E-03 0,03912554 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 4,309E-03 0,03897845 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,309E-03 0,03883246 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 4,309E-03 0,03868757 ! basic amino acid transport GO:0015802 11 5 0,000 4,309E-03 0,03854375 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,309E-03 0,03840099 ! early endosome to late endosome transport GO:0045022 12 5 0,000 4,309E-03 0,03825929 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,309E-03 0,03811863 ! depyrimidination GO:0045008 10 5 0,000 4,309E-03 0,037979 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,309E-03 0,03784039 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,309E-03 0,03770279 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,309E-03 0,03756619 ! zinc ion homeostasis GO:0055069 8 5 0,000 4,309E-03 0,03743057 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 4,309E-03 0,03729593 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 4,309E-03 0,03716225 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,309E-03 0,03702953 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,309E-03 0,03689775 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,309E-03 0,03676691 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 4,309E-03 0,03663699 ! peptidyl-arginine modification GO:0018195 9 5 0,000 4,309E-03 0,03650799 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,309E-03 0,03637989 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,309E-03 0,03625268 ! response to arsenic GO:0046685 10 5 0,000 4,309E-03 0,03612637 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 4,309E-03 0,03600093 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,309E-03 0,03587636 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 4,309E-03 0,03575265 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 4,309E-03 0,03562979 ! response to cadmium ion GO:0046686 7 5 0,000 4,309E-03 0,03550777 ! bile acid biosynthetic process GO:0006699 6 5 0,000 4,309E-03 0,03538658 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 4,309E-03 0,03526622 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,309E-03 0,03514667 ! decidualization GO:0046697 11 5 0,000 4,309E-03 0,03502793 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 4,309E-03 0,03490999 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 4,309E-03 0,03479284 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 4,309E-03 0,03467648 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 4,309E-03 0,03456089 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 4,309E-03 0,03444607 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,309E-03 0,03433201 ! neural tube patterning GO:0021532 7 5 0,000 4,309E-03 0,03421871 ! embryonic cleavage GO:0040016 6 5 0,000 4,309E-03 0,03410614 ! peroxisome fission GO:0016559 5 5 0,000 4,309E-03 0,03399432 ! histone demethylation GO:0016577 10 5 0,000 4,309E-03 0,03388323 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 4,309E-03 0,03377286 ! mitotic recombination GO:0006312 9 5 0,000 4,309E-03 0,03366321 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,309E-03 0,03355426 ! metaphase plate congression GO:0051310 7 5 0,000 4,309E-03 0,03344603 ! regulation of sterol transport GO:0032371 7 5 0,000 4,309E-03 0,03333848 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,309E-03 0,03323163 ! enteric nervous system development GO:0048484 8 5 0,000 4,309E-03 0,03312546 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 4,309E-03 0,03301996 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 4,309E-03 0,03291514 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 4,309E-03 0,03281097 ! muscle cell proliferation GO:0033002 11 5 0,000 4,309E-03 0,03270747 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,309E-03 0,03260462 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 4,309E-03 0,03250241 ! plasminogen activation GO:0031639 5 5 0,000 4,309E-03 0,03240084 ! B cell homeostasis GO:0001782 13 5 0,000 4,309E-03 0,0322999 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 4,309E-03 0,03219959 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,309E-03 0,0320999 ! metaphase GO:0051323 8 5 0,000 4,309E-03 0,03200083 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 4,309E-03 0,03190236 ! cellular response to nutrient GO:0031670 8 5 0,000 4,309E-03 0,0318045 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,309E-03 0,03170724 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 4,309E-03 0,03161057 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 4,309E-03 0,03151449 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 4,309E-03 0,03141899 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 4,309E-03 0,03132407 ! response to redox state GO:0051775 5 5 0,000 4,309E-03 0,03122972 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 4,309E-03 0,03113594 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 4,309E-03 0,03104272 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,309E-03 0,03095005 ! regulation of telomerase activity GO:0051972 6 5 0,000 4,309E-03 0,03085794 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,309E-03 0,03076637 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 4,309E-03 0,03067535 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,309E-03 0,03058486 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 4,309E-03 0,03049491 ! striatum development GO:0021756 9 5 0,000 4,309E-03 0,03040548 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 4,309E-03 0,03031657 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 4,309E-03 0,03022819 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,309E-03 0,03014031 ! glial cell migration GO:0008347 11 5 0,000 4,309E-03 0,03005295 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,309E-03 0,02996609 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 4,309E-03 0,02987973 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 4,309E-03 0,02979387 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,309E-03 0,0297085 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,309E-03 0,02962362 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,309E-03 0,02953922 ! neuroprotection GO:0043526 6 5 0,000 4,309E-03 0,02945531 ! neural plate development GO:0001840 8 5 0,000 4,309E-03 0,02937186 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,309E-03 0,02928889 ! regulation of sensory perception GO:0051931 7 5 0,000 4,309E-03 0,02920639 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,309E-03 0,02912435 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,309E-03 0,02904277 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 4,309E-03 0,02896164 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 4,309E-03 0,02888097 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,309E-03 0,02880074 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,309E-03 0,02872096 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,309E-03 0,02864162 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,309E-03 0,02856272 ! spindle assembly GO:0051225 6 5 0,000 4,309E-03 0,02848425 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,309E-03 0,02840621 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,309E-03 0,0283286 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,309E-03 0,02825141 ! drug metabolic process GO:0017144 6 5 0,000 4,309E-03 0,02817464 ! stem cell division GO:0017145 11 5 0,000 4,309E-03 0,02809829 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,309E-03 0,02802235 ! organ regeneration GO:0031100 7 5 0,000 4,309E-03 0,02794681 ! carnitine metabolic process GO:0009437 7 5 0,000 4,309E-03 0,02787169 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 4,309E-03 0,02779696 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,309E-03 0,02772264 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 5,169E-03 0,03316469 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,169E-03 0,03307649 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 5,169E-03 0,03298875 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 5,169E-03 0,03290148 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 5,169E-03 0,03281467 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 5,169E-03 0,03272831 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 5,169E-03 0,03264241 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 5,169E-03 0,03255696 ! sleep GO:0030431 13 6 0,000 5,169E-03 0,03247196 ! response to oxygen radical GO:0000305 11 6 0,000 5,169E-03 0,03238739 ! positive regulation of axon extension GO:0045773 11 6 0,000 5,169E-03 0,03230327 ! myoblast cell fate commitment GO:0048625 16 6 0,000 5,169E-03 0,03221958 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 5,169E-03 0,03213633 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 5,169E-03 0,0320535 ! regulation of interferon-beta production GO:0032648 8 6 0,000 5,169E-03 0,0319711 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 5,169E-03 0,03188913 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 5,169E-03 0,03180757 ! forebrain regionalization GO:0021871 8 6 0,000 5,169E-03 0,03172643 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 5,169E-03 0,0316457 ! male meiosis GO:0007140 7 6 0,000 5,169E-03 0,03156538 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 5,169E-03 0,03148547 ! response to zinc ion GO:0010043 9 6 0,000 5,169E-03 0,03140596 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 5,169E-03 0,03132685 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 5,169E-03 0,03124814 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 5,169E-03 0,03116982 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 5,169E-03 0,0310919 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 5,169E-03 0,03101436 ! malate metabolic process GO:0006108 11 6 0,000 5,169E-03 0,03093721 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 5,169E-03 0,03086045 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 5,169E-03 0,03078406 ! protein refolding GO:0042026 15 6 0,000 5,169E-03 0,03070805 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 5,169E-03 0,03063241 ! opsonization GO:0008228 8 6 0,000 5,169E-03 0,03055715 ! mating behavior GO:0007617 7 6 0,000 5,169E-03 0,03048225 ! neuron remodeling GO:0016322 15 6 0,000 5,169E-03 0,03040773 ! erythrocyte maturation GO:0043249 7 6 0,000 5,169E-03 0,03033356 ! embryonic hemopoiesis GO:0035162 14 6 0,000 5,169E-03 0,03025976 ! equilibrioception GO:0050957 14 6 0,000 5,169E-03 0,03018631 ! protein amino acid dealkylation GO:0008214 12 6 0,000 5,169E-03 0,03011322 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 5,169E-03 0,03004048 ! photoreceptor cell development GO:0042461 10 6 0,000 5,169E-03 0,0299681 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 5,169E-03 0,02989606 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 5,169E-03 0,02982436 ! response to interferon-gamma GO:0034341 15 6 0,000 5,169E-03 0,02975301 ! toxin metabolic process GO:0009404 11 6 0,000 5,169E-03 0,029682 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 5,169E-03 0,02961133 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 5,169E-03 0,029541 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 5,169E-03 0,02947099 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 5,169E-03 0,02940132 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 5,169E-03 0,02933198 ! cGMP-mediated signaling GO:0019934 13 6 0,000 5,169E-03 0,02926296 ! activation of MAPKKK activity GO:0000185 12 6 0,000 5,169E-03 0,02919427 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 5,169E-03 0,0291259 ! thymic T cell selection GO:0045061 12 6 0,000 5,169E-03 0,02905785 ! protein lipoylation GO:0009249 10 6 0,000 5,169E-03 0,02899012 ! cysteine metabolic process GO:0006534 10 6 0,000 5,169E-03 0,0289227 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 5,169E-03 0,02885559 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 5,169E-03 0,0287888 ! glutamate catabolic process GO:0006538 10 6 0,000 5,169E-03 0,02872231 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 5,169E-03 0,02865613 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 5,169E-03 0,02859025 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 5,169E-03 0,02852468 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 5,169E-03 0,0284594 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 5,169E-03 0,02839443 ! hyperosmotic response GO:0006972 9 6 0,000 5,169E-03 0,02832975 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 5,169E-03 0,02826536 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 5,169E-03 0,02820127 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 5,169E-03 0,02813747 ! urea metabolic process GO:0019627 7 6 0,000 5,169E-03 0,02807395 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 5,169E-03 0,02801072 ! neutrophil activation GO:0042119 8 6 0,000 5,169E-03 0,02794777 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 5,169E-03 0,02788511 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 5,169E-03 0,02782273 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 5,169E-03 0,02776062 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 5,169E-03 0,0276988 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 5,169E-03 0,02763724 ! neuron apoptosis GO:0051402 9 6 0,000 5,169E-03 0,02757596 ! nucleoside salvage GO:0043174 9 6 0,000 5,169E-03 0,02751495 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 5,169E-03 0,02745422 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 5,169E-03 0,02739374 ! T cell mediated immunity GO:0002456 16 6 0,000 5,169E-03 0,02733354 ! negative regulation of platelet activation GO:0010544 9 6 0,000 5,169E-03 0,0272736 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 5,169E-03 0,02721392 ! carnitine transport GO:0015879 10 6 0,000 5,169E-03 0,0271545 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 5,169E-03 0,02709534 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,169E-03 0,02703643 ! positive regulation of exocytosis GO:0045921 8 6 0,000 5,169E-03 0,02697779 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 5,169E-03 0,02691939 ! 5S class rRNA transcription GO:0042791 11 6 0,000 5,169E-03 0,02686125 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 5,169E-03 0,02680336 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 5,169E-03 0,02674572 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 5,169E-03 0,02668833 ! sodium ion homeostasis GO:0055078 11 6 0,000 5,169E-03 0,02663118 ! establishment of spindle localization GO:0051293 12 6 0,000 5,169E-03 0,02657427 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 5,169E-03 0,02651761 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 5,169E-03 0,02646119 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 5,169E-03 0,02640501 ! neural nucleus development GO:0048857 14 6 0,000 5,169E-03 0,02634907 ! response to UV-C GO:0010225 11 6 0,000 5,169E-03 0,02629336 ! astrocyte development GO:0014002 15 6 0,000 5,169E-03 0,02623789 ! protein targeting to lysosome GO:0006622 10 6 0,000 5,169E-03 0,02618265 ! purine base biosynthetic process GO:0009113 17 6 0,000 5,169E-03 0,02612765 ! interaction with symbiont GO:0051702 13 6 0,000 5,169E-03 0,02607287 ! regulation of dendrite development GO:0050773 16 6 0,000 5,169E-03 0,02601833 ! skeletal muscle contraction GO:0003009 6 6 0,000 5,169E-03 0,02596401 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 5,169E-03 0,02590992 ! response to copper ion GO:0046688 10 6 0,000 5,169E-03 0,02585605 ! response to exogenous dsRNA GO:0043330 10 6 0,000 5,169E-03 0,02580241 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 5,169E-03 0,02574898 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,169E-03 0,02569578 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 5,169E-03 0,0256428 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 5,169E-03 0,02559004 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 5,169E-03 0,02553749 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,169E-03 0,02548516 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,169E-03 0,02543305 ! hair follicle maturation GO:0048820 7 6 0,000 5,169E-03 0,02538114 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 5,169E-03 0,02532945 ! Schwann cell development GO:0014044 15 6 0,000 5,169E-03 0,02527797 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 5,169E-03 0,02522669 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 5,169E-03 0,02517563 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 5,169E-03 0,02512477 ! subpallium development GO:0021544 10 6 0,000 5,169E-03 0,02507411 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 5,169E-03 0,02502366 ! histone ubiquitination GO:0016574 8 6 0,000 5,169E-03 0,02497341 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 5,169E-03 0,02492337 ! maintenance of organ identity GO:0048496 9 6 0,000 5,169E-03 0,02487352 ! G2 phase GO:0051319 16 6 0,000 5,169E-03 0,02482387 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 5,169E-03 0,02477442 ! establishment of planar polarity GO:0001736 7 6 0,000 5,169E-03 0,02472517 ! regulation of mast cell activation GO:0033003 12 6 0,000 5,169E-03 0,02467611 ! membrane to membrane docking GO:0022614 14 6 0,000 5,169E-03 0,02462725 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 5,169E-03 0,02457858 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 5,169E-03 0,0245301 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 5,169E-03 0,02448181 ! receptor internalization GO:0031623 10 6 0,000 5,169E-03 0,02443371 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 5,169E-03 0,0243858 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 5,169E-03 0,02433808 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,169E-03 0,02429055 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 5,169E-03 0,0242432 ! protein deubiquitination GO:0016579 14 6 0,000 5,169E-03 0,02419603 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 5,169E-03 0,02414905 ! protein destabilization GO:0031648 9 6 0,000 5,169E-03 0,02410225 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 5,169E-03 0,02405563 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 5,169E-03 0,02400919 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 5,169E-03 0,02396293 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 5,169E-03 0,02391685 ! progesterone metabolic process GO:0042448 10 6 0,000 5,169E-03 0,02387094 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 5,169E-03 0,02382521 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 5,169E-03 0,02377966 ! negative regulation of axon extension GO:0030517 21 6 0,000 5,169E-03 0,02373427 ! removal of superoxide radicals GO:0019430 11 6 0,000 5,169E-03 0,02368907 ! triglyceride catabolic process GO:0019433 10 6 0,000 5,169E-03 0,02364403 ! determination of adult lifespan GO:0008340 15 6 0,000 5,169E-03 0,02359916 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 5,169E-03 0,02355447 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 5,169E-03 0,02350994 ! cerebellar cortex formation GO:0021697 8 6 0,000 5,169E-03 0,02346558 ! catecholamine transport GO:0051937 9 6 0,000 5,169E-03 0,02342139 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 5,169E-03 0,02337737 ! sensory cilium assembly GO:0035058 10 6 0,000 5,169E-03 0,02333351 ! organ or tissue specific immune response GO:0002251 7 6 0,000 5,169E-03 0,02328981 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 5,169E-03 0,02324628 ! maternal placenta development GO:0001893 12 6 0,000 5,169E-03 0,02320291 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 5,169E-03 0,0231597 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 5,169E-03 0,02311665 ! negative regulation of B cell activation GO:0050869 13 6 0,000 5,169E-03 0,02307377 ! protein amino acid prenylation GO:0018346 16 6 0,000 5,169E-03 0,02303104 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 5,169E-03 0,02298847 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 5,169E-03 0,02294605 ! positive regulation of coagulation GO:0050820 12 6 0,000 5,169E-03 0,02290379 ! tRNA transcription GO:0009304 14 7 0,000 6,028E-03 0,02666091 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 6,028E-03 0,02661199 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 6,028E-03 0,02656325 ! behavioral response to cocaine GO:0048148 14 7 0,000 6,028E-03 0,02651469 ! regulation of helicase activity GO:0051095 15 7 0,000 6,028E-03 0,0264663 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 6,028E-03 0,02641809 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 6,028E-03 0,02637006 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 6,028E-03 0,0263222 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 6,028E-03 0,02627452 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 6,028E-03 0,02622701 ! prostate gland development GO:0030850 13 7 0,000 6,028E-03 0,02617966 ! nucleotide-sugar transport GO:0015780 12 7 0,000 6,028E-03 0,02613249 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,028E-03 0,02608549 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 6,028E-03 0,02603866 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 6,028E-03 0,025992 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,028E-03 0,0259455 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 6,028E-03 0,02589917 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 6,028E-03 0,025853 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 6,028E-03 0,025807 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 6,028E-03 0,02576116 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 6,028E-03 0,02571549 ! SMAD protein complex assembly GO:0007183 12 7 0,000 6,028E-03 0,02566997 ! glycolipid transport GO:0046836 10 7 0,000 6,028E-03 0,02562462 ! protein amino acid sulfation GO:0006477 10 7 0,000 6,028E-03 0,02557943 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 6,028E-03 0,02553439 ! neuron adhesion GO:0007158 12 7 0,000 6,028E-03 0,02548951 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 6,028E-03 0,0254448 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 6,028E-03 0,02540023 ! actin-myosin filament sliding GO:0033275 11 7 0,000 6,028E-03 0,02535583 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 6,028E-03 0,02531158 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 6,028E-03 0,02526748 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 6,028E-03 0,02522354 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 6,028E-03 0,02517975 ! mRNA stabilization GO:0048255 18 7 0,000 6,028E-03 0,02513611 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 6,028E-03 0,02509262 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 6,028E-03 0,02504928 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 6,028E-03 0,02500609 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 6,028E-03 0,02496305 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 6,028E-03 0,02492016 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 6,028E-03 0,02487742 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 6,028E-03 0,02483482 ! lipoprotein transport GO:0042953 14 7 0,000 6,028E-03 0,02479237 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 6,028E-03 0,02475006 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 6,028E-03 0,02470789 ! rhythmic behavior GO:0007622 15 7 0,000 6,028E-03 0,02466587 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 6,028E-03 0,024624 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 6,028E-03 0,02458226 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 6,028E-03 0,02454067 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 6,028E-03 0,02449921 ! regulation of odontogenesis GO:0042481 13 7 0,000 6,028E-03 0,0244579 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 6,028E-03 0,02441672 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 6,028E-03 0,02437569 ! mechanosensory behavior GO:0007638 14 7 0,000 6,028E-03 0,02433479 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 6,028E-03 0,02429403 ! positive regulation of isotype switching GO:0045830 15 7 0,000 6,028E-03 0,0242534 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 6,028E-03 0,02421291 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,028E-03 0,02417256 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,028E-03 0,02413234 ! spinal cord patterning GO:0021511 13 7 0,000 6,028E-03 0,02409225 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 6,028E-03 0,0240523 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 6,028E-03 0,02401247 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 6,028E-03 0,02397278 ! adrenal gland development GO:0030325 17 7 0,000 6,028E-03 0,02393322 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 6,028E-03 0,0238938 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 6,028E-03 0,0238545 ! ovulation GO:0030728 9 7 0,000 6,028E-03 0,02381533 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 6,028E-03 0,02377629 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 6,028E-03 0,02373737 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 6,028E-03 0,02369858 ! microtubule nucleation GO:0007020 20 7 0,000 6,028E-03 0,02365992 ! proline biosynthetic process GO:0006561 10 7 0,000 6,028E-03 0,02362139 ! thyroid hormone generation GO:0006590 13 7 0,000 6,028E-03 0,02358298 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 6,028E-03 0,0235447 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 6,028E-03 0,02350654 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 6,028E-03 0,0234685 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,028E-03 0,02343059 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 6,028E-03 0,0233928 ! galactose metabolic process GO:0006012 13 7 0,000 6,028E-03 0,02335513 ! vesicle fusion GO:0006906 17 7 0,000 6,028E-03 0,02331758 ! response to dietary excess GO:0002021 8 7 0,000 6,028E-03 0,02328015 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 6,028E-03 0,02324284 ! intracellular pH reduction GO:0051452 11 7 0,000 6,028E-03 0,02320565 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 6,028E-03 0,02316858 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 6,028E-03 0,02313163 ! organ growth GO:0035265 15 7 0,000 6,028E-03 0,0230948 ! purine salvage GO:0043101 10 7 0,000 6,028E-03 0,02305808 ! nucleoside transport GO:0015858 8 7 0,000 6,028E-03 0,02302148 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 6,028E-03 0,022985 ! parturition GO:0007567 14 7 0,000 6,028E-03 0,02294863 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 6,028E-03 0,02291238 ! rRNA modification GO:0000154 14 7 0,000 6,028E-03 0,02287624 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 6,028E-03 0,02284021 ! spindle checkpoint GO:0031577 15 7 0,000 6,028E-03 0,0228043 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 6,028E-03 0,0227685 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 6,028E-03 0,02273281 ! macrophage differentiation GO:0030225 11 7 0,000 6,028E-03 0,02269724 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 6,028E-03 0,02266177 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 6,028E-03 0,02262642 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 6,028E-03 0,02259117 ! hyaluronan metabolic process GO:0030212 8 7 0,000 6,028E-03 0,02255604 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 6,028E-03 0,02252102 ! anterograde axon cargo transport GO:0008089 18 7 0,000 6,028E-03 0,0224861 ! fibrinolysis GO:0042730 10 7 0,000 6,028E-03 0,02245129 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 6,028E-03 0,02241659 ! eating behavior GO:0042755 7 7 0,000 6,028E-03 0,022382 ! B cell lineage commitment GO:0002326 21 7 0,000 6,028E-03 0,02234751 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 6,028E-03 0,02231313 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 6,028E-03 0,02227885 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 6,028E-03 0,02224468 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 6,028E-03 0,02221062 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 6,028E-03 0,02217666 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 6,028E-03 0,0221428 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 6,028E-03 0,02210905 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 6,028E-03 0,02207539 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 6,028E-03 0,02204185 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 6,028E-03 0,0220084 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 6,028E-03 0,02197505 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 6,028E-03 0,02194181 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 6,028E-03 0,02190866 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 6,028E-03 0,02187562 ! regulation of meiosis GO:0040020 12 7 0,000 6,028E-03 0,02184267 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 6,028E-03 0,02180983 ! T cell lineage commitment GO:0002360 16 7 0,000 6,028E-03 0,02177708 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 6,028E-03 0,02174443 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 6,028E-03 0,02171188 ! oxygen homeostasis GO:0032364 12 7 0,000 6,028E-03 0,02167942 ! transcription termination GO:0006353 13 7 0,000 6,028E-03 0,02164707 ! response to tumor cell GO:0002347 13 7 0,000 6,028E-03 0,0216148 ! regulation of respiratory burst GO:0060263 11 7 0,000 6,028E-03 0,02158264 ! coenzyme A metabolic process GO:0015936 12 7 0,000 6,028E-03 0,02155057 ! anaphase GO:0051322 17 7 0,000 6,028E-03 0,0215186 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 6,028E-03 0,02148672 ! axonal fasciculation GO:0007413 18 7 0,000 6,028E-03 0,02145493 ! negative regulation of nuclear division GO:0051784 14 7 0,000 6,028E-03 0,02142324 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 6,028E-03 0,02139164 ! peptidyl-threonine modification GO:0018210 25 7 0,000 6,028E-03 0,02136014 ! diuresis GO:0030146 12 7 0,000 6,028E-03 0,02132873 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 6,028E-03 0,02129741 ! thiamin metabolic process GO:0006772 7 7 0,000 6,028E-03 0,02126618 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,028E-03 0,02123504 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 6,028E-03 0,021204 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 6,028E-03 0,02117304 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,028E-03 0,02114218 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 6,028E-03 0,0211114 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 6,028E-03 0,02108072 ! melanin biosynthetic process GO:0042438 8 7 0,000 6,028E-03 0,02105012 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 6,028E-03 0,02101961 ! dopamine biosynthetic process GO:0042416 18 7 0,000 6,028E-03 0,0209892 ! glycolipid catabolic process GO:0019377 15 7 0,000 6,028E-03 0,02095886 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 6,028E-03 0,02092862 ! lymph node development GO:0048535 10 7 0,000 6,028E-03 0,02089846 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 6,028E-03 0,02086839 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 6,028E-03 0,02083841 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 6,028E-03 0,02080851 ! endosome to lysosome transport GO:0008333 11 7 0,000 6,028E-03 0,0207787 ! protein modification by small protein removal GO:0070646 16 7 0,000 6,028E-03 0,02074898 ! adult feeding behavior GO:0008343 9 7 0,000 6,028E-03 0,02071933 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 6,028E-03 0,02068978 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 6,028E-03 0,0206603 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,028E-03 0,02063092 ! muscle adaptation GO:0043500 14 7 0,000 6,028E-03 0,02060161 ! embryonic heart tube development GO:0035050 10 7 0,000 6,028E-03 0,02057239 ! retina homeostasis GO:0001895 12 7 0,000 6,028E-03 0,02054325 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 6,028E-03 0,02051419 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 6,028E-03 0,02048522 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 6,028E-03 0,02045632 ! protein prenylation GO:0018342 18 7 0,000 6,028E-03 0,02042751 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 6,028E-03 0,02039878 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 6,028E-03 0,02037013 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 6,028E-03 0,02034156 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 6,886E-03 0,02320531 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 6,886E-03 0,02317286 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 6,886E-03 0,02314049 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 6,886E-03 0,02310822 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 6,886E-03 0,02307603 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 6,886E-03 0,02304394 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 6,886E-03 0,02301193 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 6,886E-03 0,02298002 ! neutral lipid catabolic process GO:0046461 13 8 0,000 6,886E-03 0,02294819 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 6,886E-03 0,02291645 ! meiotic prophase I GO:0007128 13 8 0,000 6,886E-03 0,0228848 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 6,886E-03 0,02285323 ! oligopeptide transport GO:0006857 15 8 0,000 6,886E-03 0,02282175 ! UTP metabolic process GO:0046051 8 8 0,000 6,886E-03 0,02279036 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 6,886E-03 0,02275906 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 6,886E-03 0,02272784 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 6,886E-03 0,0226967 ! macrophage chemotaxis GO:0048246 12 8 0,000 6,886E-03 0,02266565 ! succinate metabolic process GO:0006105 14 8 0,000 6,886E-03 0,02263469 ! membrane hyperpolarization GO:0060081 10 8 0,000 6,886E-03 0,02260381 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 6,886E-03 0,02257301 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 6,886E-03 0,0225423 ! T-helper 1 type immune response GO:0042088 12 8 0,000 6,886E-03 0,02251167 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 6,886E-03 0,02248113 GO:0032107|regulation of response to nutrient levels, ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,886E-03 0,02245067 ! ganglioside metabolic process GO:0001573 19 8 0,000 6,886E-03 0,02242029 ! reflex GO:0060004 16 8 0,000 6,886E-03 0,02238999 ! negative regulation of endocytosis GO:0045806 11 8 0,000 6,886E-03 0,02235977 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 6,886E-03 0,02232964 ! endothelial cell differentiation GO:0045446 17 8 0,000 6,886E-03 0,02229959 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 6,886E-03 0,02226961 ! glycerolipid catabolic process GO:0046503 13 8 0,000 6,886E-03 0,02223972 ! hemoglobin metabolic process GO:0020027 13 8 0,000 6,886E-03 0,02220991 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 6,886E-03 0,02218018 ! pigment granule organization GO:0048753 16 8 0,000 6,886E-03 0,02215052 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 6,886E-03 0,02212095 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 6,886E-03 0,02209146 ! astrocyte differentiation GO:0048708 18 8 0,000 6,886E-03 0,02206204 ! histidine metabolic process GO:0006547 16 8 0,000 6,886E-03 0,0220327 GO:0009075|histidine family amino acid metabolic process, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 6,886E-03 0,02200344 ! glycine catabolic process GO:0006546 13 8 0,000 6,886E-03 0,02197426 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 6,886E-03 0,02194516 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 6,886E-03 0,02191613 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 6,886E-03 0,02188718 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 6,886E-03 0,0218583 ! regulation of pigmentation during development GO:0048070 24 8 0,000 6,886E-03 0,0218295 ! melanin metabolic process GO:0006582 15 8 0,000 6,886E-03 0,02180078 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 6,886E-03 0,02177213 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 6,886E-03 0,02174356 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 6,886E-03 0,02171506 ! macrophage activation GO:0042116 12 8 0,000 6,886E-03 0,02168664 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 6,886E-03 0,02165829 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 6,886E-03 0,02163002 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 6,886E-03 0,02160182 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 6,886E-03 0,02157369 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 6,886E-03 0,02154563 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 6,886E-03 0,02151765 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,886E-03 0,02148974 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 6,886E-03 0,02146191 ! osteoblast development GO:0002076 16 8 0,000 6,886E-03 0,02143414 ! positive regulation of vasodilation GO:0045909 13 8 0,000 6,886E-03 0,02140645 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 6,886E-03 0,02137883 ! negative regulation of translational initiation GO:0045947 10 8 0,000 6,886E-03 0,02135128 ! Schwann cell differentiation GO:0014037 19 8 0,000 6,886E-03 0,0213238 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 6,886E-03 0,02129639 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 6,886E-03 0,02126905 ! response to UV-B GO:0010224 16 8 0,000 6,886E-03 0,02124179 ! protein targeting to vacuole GO:0006623 12 8 0,000 6,886E-03 0,02121459 ! protein retention in ER lumen GO:0006621 14 8 0,000 6,886E-03 0,02118746 ! intermediate filament organization GO:0045109 12 8 0,000 6,886E-03 0,0211604 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 6,886E-03 0,02113341 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 6,886E-03 0,02110649 ! cellular extravasation GO:0045123 12 8 0,000 6,886E-03 0,02107963 ! cardiac muscle cell development GO:0055013 13 8 0,000 6,886E-03 0,02105285 ! regulation of circadian rhythm GO:0042752 16 8 0,000 6,886E-03 0,02102613 ! response to antibiotic GO:0046677 11 8 0,000 6,886E-03 0,02099948 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 6,886E-03 0,0209729 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 6,886E-03 0,02094639 ! DNA topological change GO:0006265 12 8 0,000 6,886E-03 0,02091994 ! response to tropane GO:0014073 15 8 0,000 6,886E-03 0,02089356 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 6,886E-03 0,02086724 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 6,886E-03 0,020841 ! melanosome transport GO:0032402 13 8 0,000 6,886E-03 0,02081481 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 6,886E-03 0,0207887 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 6,886E-03 0,02076265 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 6,886E-03 0,02073666 ! mast cell activation GO:0045576 14 8 0,000 6,886E-03 0,02071074 ! multicellular organismal aging GO:0010259 18 8 0,000 6,886E-03 0,02068488 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 6,886E-03 0,02065909 ! dendrite morphogenesis GO:0048813 13 8 0,000 6,886E-03 0,02063337 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 6,886E-03 0,0206077 ! nucleosome disassembly GO:0006337 14 8 0,000 6,886E-03 0,0205821 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 6,886E-03 0,02055657 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 6,886E-03 0,02053109 ! leukocyte activation during immune response GO:0002366 13 8 0,000 6,886E-03 0,02050568 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 6,886E-03 0,02048034 ! establishment of chromosome localization GO:0051303 12 8 0,000 6,886E-03 0,02045505 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 6,886E-03 0,02042983 ! intracellular lipid transport GO:0032365 13 8 0,000 6,886E-03 0,02040467 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 6,886E-03 0,02037957 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 6,886E-03 0,02035454 ! regulation of macrophage activation GO:0043030 15 8 0,000 6,886E-03 0,02032956 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 6,886E-03 0,02030465 ! positive regulation of epidermis development GO:0045684 13 8 0,000 6,886E-03 0,02027979 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 6,886E-03 0,020255 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 6,886E-03 0,02023027 ! hormone catabolic process GO:0042447 17 8 0,000 6,886E-03 0,0202056 ! positive regulation of glucose import GO:0046326 8 8 0,000 6,886E-03 0,02018099 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 6,886E-03 0,02015644 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 6,886E-03 0,02013195 ! ATP catabolic process GO:0006200 11 8 0,000 6,886E-03 0,02010752 ! blastocyst growth GO:0001832 19 8 0,000 6,886E-03 0,02008314 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 6,886E-03 0,02005883 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 6,886E-03 0,02003457 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 6,886E-03 0,02001038 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 6,886E-03 0,01998624 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 6,886E-03 0,01996216 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 6,886E-03 0,01993814 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 6,886E-03 0,01991417 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 6,886E-03 0,01989027 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 6,886E-03 0,01986642 ! amino sugar catabolic process GO:0046348 10 8 0,000 6,886E-03 0,01984263 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 6,886E-03 0,01981889 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 6,886E-03 0,01979521 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 6,886E-03 0,01977159 ! behavioral response to nicotine GO:0035095 12 8 0,000 6,886E-03 0,01974802 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 6,886E-03 0,01972451 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 6,886E-03 0,01970106 ! NAD biosynthetic process GO:0009435 13 8 0,000 6,886E-03 0,01967766 ! regulation of developmental growth GO:0048638 15 9 0,000 7,744E-03 0,02210194 ! axon extension GO:0048675 15 9 0,000 7,744E-03 0,02207575 ! autophagic vacuole formation GO:0000045 15 9 0,000 7,744E-03 0,02204963 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 7,744E-03 0,02202357 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 7,744E-03 0,02199756 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 7,744E-03 0,02197162 ! pentose-phosphate shunt GO:0006098 16 9 0,000 7,744E-03 0,02194574 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 7,744E-03 0,02191992 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 7,744E-03 0,02189417 ! cell proliferation in forebrain GO:0021846 15 9 0,000 7,744E-03 0,02186847 ! phosphate transport GO:0006817 19 9 0,000 7,744E-03 0,02184283 ! reproductive behavior GO:0019098 19 9 0,000 7,744E-03 0,02181726 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 7,744E-03 0,02179174 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 7,744E-03 0,02176628 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 7,744E-03 0,02174088 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 7,744E-03 0,02171554 ! GTP metabolic process GO:0046039 9 9 0,000 7,744E-03 0,02169026 ! RNA methylation GO:0001510 15 9 0,000 7,744E-03 0,02166504 ! elastic fiber assembly GO:0048251 15 9 0,000 7,744E-03 0,02163988 ! induction of positive chemotaxis GO:0050930 15 9 0,000 7,744E-03 0,02161478 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 7,744E-03 0,02158973 ! artery development GO:0060840 24 9 0,000 7,744E-03 0,02156474 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 7,744E-03 0,02153981 ! regulation of glycolysis GO:0006110 21 9 0,000 7,744E-03 0,02151494 ! cerebral cortex cell migration GO:0021795 15 9 0,000 7,744E-03 0,02149012 ! chemosensory behavior GO:0007635 20 9 0,000 7,744E-03 0,02146536 ! microtubule bundle formation GO:0001578 21 9 0,000 7,744E-03 0,02144066 ! middle ear morphogenesis GO:0042474 14 9 0,000 7,744E-03 0,02141602 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 7,744E-03 0,02139143 ! leukocyte degranulation GO:0043299 16 9 0,000 7,744E-03 0,0213669 ! bile acid and bile salt transport GO:0015721 13 9 0,000 7,744E-03 0,02134242 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 7,744E-03 0,021318 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 7,744E-03 0,02129364 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 7,744E-03 0,02126933 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 7,744E-03 0,02124508 ! protein targeting to ER GO:0045047 22 9 0,000 7,744E-03 0,02122088 ! ceramide biosynthetic process GO:0046513 19 9 0,000 7,744E-03 0,02119674 ! T cell selection GO:0045058 23 9 0,000 7,744E-03 0,02117265 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 7,744E-03 0,02114862 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 7,744E-03 0,02112464 ! phosphagen metabolic process GO:0006599 12 9 0,000 7,744E-03 0,02110072 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 7,744E-03 0,02107685 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 7,744E-03 0,02105304 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 7,744E-03 0,02102927 ! regulation of type I interferon production GO:0032479 12 9 0,000 7,744E-03 0,02100556 ! mannose metabolic process GO:0006013 13 9 0,000 7,744E-03 0,02098191 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 7,744E-03 0,02095831 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 7,744E-03 0,02093476 ! Rac protein signal transduction GO:0016601 17 9 0,000 7,744E-03 0,02091126 ! receptor clustering GO:0043113 18 9 0,000 7,744E-03 0,02088782 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 7,744E-03 0,02086443 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 7,744E-03 0,02084109 ! ruffle organization GO:0031529 15 9 0,000 7,744E-03 0,02081781 ! retinol metabolic process GO:0042572 18 9 0,000 7,744E-03 0,02079457 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 7,744E-03 0,02077139 ! behavioral fear response GO:0001662 22 9 0,000 7,744E-03 0,02074826 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 7,744E-03 0,02072518 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 7,744E-03 0,02070215 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 7,744E-03 0,02067917 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 7,744E-03 0,02065625 ! protein heterooligomerization GO:0051291 16 9 0,000 7,744E-03 0,02063337 ! oligodendrocyte development GO:0014003 10 9 0,000 7,744E-03 0,02061055 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 7,744E-03 0,02058777 ! segment specification GO:0007379 13 9 0,000 7,744E-03 0,02056505 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 7,744E-03 0,02054238 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 7,744E-03 0,02051975 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 7,744E-03 0,02049718 ! response to amine stimulus GO:0014075 13 9 0,000 7,744E-03 0,02047466 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 7,744E-03 0,02045218 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 7,744E-03 0,02042975 ! erythrocyte development GO:0048821 15 9 0,000 7,744E-03 0,02040738 ! gas homeostasis GO:0033483 16 9 0,000 7,744E-03 0,02038505 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 7,744E-03 0,02036277 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 7,744E-03 0,02034054 ! renal water homeostasis GO:0003091 14 9 0,000 7,744E-03 0,02031836 ! postreplication repair GO:0006301 22 9 0,000 7,744E-03 0,02029623 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 7,744E-03 0,02027414 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 7,744E-03 0,0202521 ! icosanoid secretion GO:0032309 15 9 0,000 7,744E-03 0,02023012 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 7,744E-03 0,02020817 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 7,744E-03 0,02018628 ! regulation of cell division GO:0051302 15 9 0,000 7,744E-03 0,02016443 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 7,744E-03 0,02014263 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 7,744E-03 0,02012088 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 7,744E-03 0,02009918 ! sterol catabolic process GO:0016127 11 9 0,000 7,744E-03 0,02007752 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 7,744E-03 0,02005591 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 7,744E-03 0,02003434 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 7,744E-03 0,02001282 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 7,744E-03 0,01999135 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 7,744E-03 0,01996992 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 7,744E-03 0,01994854 ! musculoskeletal movement GO:0050881 14 9 0,000 7,744E-03 0,0199272 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 7,744E-03 0,01990591 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 7,744E-03 0,01988467 ! regulation of synaptogenesis GO:0051963 15 9 0,000 7,744E-03 0,01986347 ! purine base metabolic process GO:0006144 21 9 0,000 7,744E-03 0,01984232 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 7,744E-03 0,01982121 ! pigment granule transport GO:0051904 17 9 0,000 7,744E-03 0,01980014 ! regulation of fibrinolysis GO:0051917 16 9 0,000 7,744E-03 0,01977913 ! regulation of telomere maintenance GO:0032204 14 9 0,000 7,744E-03 0,01975815 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 7,744E-03 0,01973722 ! regulation of muscle adaptation GO:0043502 14 9 0,000 7,744E-03 0,01971633 ! regulation of amino acid transport GO:0051955 11 9 0,000 7,744E-03 0,01969549 ! mitochondrion localization GO:0051646 15 9 0,000 7,744E-03 0,01967469 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 8,601E-03 0,02182866 ! negative regulation of blood pressure GO:0045776 26 10 0,000 8,601E-03 0,02180566 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 8,601E-03 0,0217827 ! regulation of phosphatase activity GO:0010921 28 10 0,000 8,601E-03 0,0217598 ! synapsis GO:0007129 13 10 0,000 8,601E-03 0,02173694 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 8,601E-03 0,02171413 ! N-glycan processing GO:0006491 20 10 0,000 8,601E-03 0,02169137 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 8,601E-03 0,02166866 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 8,601E-03 0,02164599 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 8,601E-03 0,02162337 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 8,601E-03 0,0216008 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 8,601E-03 0,02157828 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 8,601E-03 0,0215558 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 8,601E-03 0,02153337 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 8,601E-03 0,02151098 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 8,601E-03 0,02148865 ! androgen metabolic process GO:0008209 17 10 0,000 8,601E-03 0,02146636 ! phospholipid efflux GO:0033700 16 10 0,000 8,601E-03 0,02144411 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 8,601E-03 0,02142191 ! positive regulation of heart contraction GO:0045823 16 10 0,000 8,601E-03 0,02139976 ! lung alveolus development GO:0048286 26 10 0,000 8,601E-03 0,02137765 ! pathogenesis GO:0009405 13 10 0,000 8,601E-03 0,02135559 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 8,601E-03 0,02133357 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 8,601E-03 0,0213116 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 8,601E-03 0,02128968 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 8,601E-03 0,0212678 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 8,601E-03 0,02124596 ! endoderm development GO:0007492 16 10 0,000 8,601E-03 0,02122417 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 8,601E-03 0,02120242 ! arginine catabolic process GO:0006527 13 10 0,000 8,601E-03 0,02118072 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 8,601E-03 0,02115907 ! proline metabolic process GO:0006560 13 10 0,000 8,601E-03 0,02113745 ! glucan biosynthetic process GO:0009250 14 10 0,000 8,601E-03 0,02111588 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 8,601E-03 0,02109436 ! polyamine biosynthetic process GO:0006596 12 10 0,000 8,601E-03 0,02107288 ! V(D)J recombination GO:0033151 28 10 0,000 8,601E-03 0,02105144 ! reverse cholesterol transport GO:0043691 16 10 0,000 8,601E-03 0,02103005 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 8,601E-03 0,0210087 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 8,601E-03 0,02098739 ! B cell proliferation GO:0042100 18 10 0,000 8,601E-03 0,02096613 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 8,601E-03 0,02094491 ! regulation of sodium ion transport GO:0002028 21 10 0,000 8,601E-03 0,02092373 ! multicellular organism growth GO:0035264 18 10 0,000 8,601E-03 0,02090259 ! phagocytosis, engulfment GO:0006911 28 10 0,000 8,601E-03 0,0208815 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 8,601E-03 0,02086045 ! epithelial cell development GO:0002064 20 10 0,000 8,601E-03 0,02083944 ! lens development in camera-type eye GO:0002088 16 10 0,000 8,601E-03 0,02081848 ! retinoic acid metabolic process GO:0042573 14 10 0,000 8,601E-03 0,02079755 ! macroautophagy GO:0016236 17 10 0,000 8,601E-03 0,02077667 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 8,601E-03 0,02075583 ! positive regulation of translational initiation GO:0045948 11 10 0,000 8,601E-03 0,02073504 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 8,601E-03 0,02071428 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 8,601E-03 0,02069357 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 8,601E-03 0,02067289 ! copper ion homeostasis GO:0055070 13 10 0,000 8,601E-03 0,02065226 ! regulation of bone resorption GO:0045124 25 10 0,000 8,601E-03 0,02063167 ! regulation of gliogenesis GO:0014013 23 10 0,000 8,601E-03 0,02061112 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 8,601E-03 0,02059061 ! alpha-beta T cell activation GO:0046631 23 10 0,000 8,601E-03 0,02057015 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 8,601E-03 0,02054972 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 8,601E-03 0,02052933 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 8,601E-03 0,02050899 ! blastoderm segmentation GO:0007350 18 10 0,000 8,601E-03 0,02048868 ! response to dsRNA GO:0043331 20 10 0,000 8,601E-03 0,02046841 ! DNA ligation GO:0006266 19 10 0,000 8,601E-03 0,02044819 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 8,601E-03 0,020428 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 8,601E-03 0,02040786 ! melanosome localization GO:0032400 16 10 0,000 8,601E-03 0,02038775 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 8,601E-03 0,02036768 ! regulation of B cell differentiation GO:0045577 19 10 0,000 8,601E-03 0,02034766 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 8,601E-03 0,02032767 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 8,601E-03 0,02030772 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 8,601E-03 0,02028781 ! mRNA cleavage GO:0006379 17 10 0,000 8,601E-03 0,02026794 ! protein sumoylation GO:0016925 15 10 0,000 8,601E-03 0,02024811 ! hindbrain morphogenesis GO:0021575 19 10 0,000 8,601E-03 0,02022832 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 8,601E-03 0,02020856 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 8,601E-03 0,02018885 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 8,601E-03 0,02016917 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 8,601E-03 0,02014953 ! salivary gland development GO:0007431 27 10 0,000 8,601E-03 0,02012993 ! prophase GO:0051324 15 10 0,000 8,601E-03 0,02011037 ! negative regulation of neurological system process GO:0031645 19 10 0,000 8,601E-03 0,02009084 ! apical protein localization GO:0045176 15 10 0,000 8,601E-03 0,02007135 ! ubiquinone metabolic process GO:0006743 15 10 0,000 8,601E-03 0,02005191 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 8,601E-03 0,02003249 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 8,601E-03 0,02001312 ! midbrain development GO:0030901 13 10 0,000 8,601E-03 0,01999378 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 8,601E-03 0,01997449 ! methionine biosynthetic process GO:0009086 19 10 0,000 8,601E-03 0,01995522 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 8,601E-03 0,019936 ! quaternary ammonium group transport GO:0015697 21 10 0,000 8,601E-03 0,01991681 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 8,601E-03 0,01989766 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 8,601E-03 0,01987855 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 8,601E-03 0,01985947 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 8,601E-03 0,01984043 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 8,601E-03 0,01982142 ! oocyte development GO:0048599 17 10 0,000 8,601E-03 0,01980246 ! establishment of pigment granule localization GO:0051905 18 10 0,000 8,601E-03 0,01978352 ! blastocyst formation GO:0001825 17 10 0,000 8,601E-03 0,01976463 ! cerebellar cortex development GO:0021695 15 10 0,000 8,601E-03 0,01974577 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 8,601E-03 0,01972695 ! activation of innate immune response GO:0002218 12 10 0,000 8,601E-03 0,01970816 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 8,601E-03 0,01968941 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 8,601E-03 0,01967069 ! response to nicotine GO:0035094 20 10 0,000 8,601E-03 0,01965201 ! establishment of cell polarity GO:0030010 16 10 0,000 8,601E-03 0,01963336 ! negative regulation of immune effector process GO:0002698 20 10 0,000 8,601E-03 0,01961476 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 8,601E-03 0,01959618 ! localization within membrane GO:0051668 20 10 0,000 8,601E-03 0,01957764 ! negative regulation of muscle development GO:0048635 20 11 0,000 9,457E-03 0,02150613 ! respiratory burst GO:0045730 17 11 0,000 9,457E-03 0,02148582 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 9,457E-03 0,02146555 ! neuron fate specification GO:0048665 17 11 0,000 9,457E-03 0,02144532 ! telencephalon cell migration GO:0022029 20 11 0,000 9,457E-03 0,02142513 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 9,457E-03 0,02140497 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 9,457E-03 0,02138485 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 9,457E-03 0,02136477 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 9,457E-03 0,02134473 ! Golgi vesicle budding GO:0048194 22 11 0,000 9,457E-03 0,02132473 ! response to pain GO:0048265 24 11 0,000 9,457E-03 0,02130476 ! detection of mechanical stimulus GO:0050982 22 11 0,000 9,457E-03 0,02128483 ! T cell proliferation GO:0042098 26 11 0,000 9,457E-03 0,02126494 ! blood vessel remodeling GO:0001974 29 11 0,000 9,457E-03 0,02124508 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 9,457E-03 0,02122527 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 9,457E-03 0,02120548 ! bone resorption GO:0045453 16 11 0,000 9,457E-03 0,02118574 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 9,457E-03 0,02116603 ! ventral spinal cord development GO:0021517 21 11 0,000 9,457E-03 0,02114636 ! negative regulation of proteolysis GO:0045861 25 11 0,000 9,457E-03 0,02112673 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 9,457E-03 0,02110713 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 9,457E-03 0,02108757 ! melanocyte differentiation GO:0030318 21 11 0,000 9,457E-03 0,02106804 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 9,457E-03 0,02104855 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 9,457E-03 0,0210291 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 9,457E-03 0,02100968 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 9,457E-03 0,0209903 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 9,457E-03 0,02097095 ! lipid digestion GO:0044241 18 11 0,000 9,457E-03 0,02095164 ! substrate-bound cell migration GO:0006929 13 11 0,000 9,457E-03 0,02093237 ! UV protection GO:0009650 19 11 0,000 9,457E-03 0,02091313 ! adult heart development GO:0007512 14 11 0,000 9,457E-03 0,02089393 ! chondrocyte differentiation GO:0002062 24 11 0,000 9,457E-03 0,02087476 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 9,457E-03 0,02085562 ! temperature homeostasis GO:0001659 17 11 0,000 9,457E-03 0,02083652 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 9,457E-03 0,02081746 ! negative regulation of ossification GO:0030279 26 11 0,000 9,457E-03 0,02079843 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 9,457E-03 0,02077944 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 9,457E-03 0,02076048 ! regulation of organ growth GO:0046620 13 11 0,000 9,457E-03 0,02074155 ! pigment granule localization GO:0051875 20 11 0,000 9,457E-03 0,02072266 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 9,457E-03 0,02070381 ! vasoconstriction GO:0042310 18 11 0,000 9,457E-03 0,02068499 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 9,457E-03 0,0206662 ! embryonic axis specification GO:0000578 18 11 0,000 9,457E-03 0,02064745 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 9,457E-03 0,02062873 ! snRNA metabolic process GO:0016073 24 11 0,000 9,457E-03 0,02061004 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 9,457E-03 0,02059139 ! nitric oxide metabolic process GO:0046209 15 11 0,000 9,457E-03 0,02057277 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 9,457E-03 0,02055419 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 9,457E-03 0,02053564 ! zymogen activation GO:0031638 15 11 0,000 9,457E-03 0,02051712 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 9,457E-03 0,02049864 ! neuroblast proliferation GO:0007405 24 11 0,000 9,457E-03 0,02048018 ! nucleosome positioning GO:0016584 15 11 0,000 9,457E-03 0,02046177 ! regulation of isotype switching GO:0045191 22 11 0,000 9,457E-03 0,02044338 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 9,457E-03 0,02042503 ! glutathione biosynthetic process GO:0006750 13 11 0,000 9,457E-03 0,02040671 ! regulation of leukocyte migration GO:0002685 26 11 0,000 9,457E-03 0,02038843 ! acid secretion GO:0046717 18 11 0,000 9,457E-03 0,02037017 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 9,457E-03 0,02035195 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 9,457E-03 0,02033377 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 9,457E-03 0,02031561 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 9,457E-03 0,02029749 ! oocyte differentiation GO:0009994 18 11 0,000 9,457E-03 0,0202794 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 9,457E-03 0,02026134 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 9,457E-03 0,02024331 ! anterior/posterior axis specification GO:0009948 18 11 0,000 9,457E-03 0,02022532 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 9,457E-03 0,02020736 ! negative regulation of glucose import GO:0046325 17 11 0,000 9,457E-03 0,02018943 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 9,457E-03 0,02017153 ! embryonic gut development GO:0048566 15 11 0,000 9,457E-03 0,02015366 ! regulation of organic acid transport GO:0032890 18 11 0,000 9,457E-03 0,02013583 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 9,457E-03 0,02011802 ! cardiac cell differentiation GO:0035051 31 11 0,000 9,457E-03 0,02010025 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 9,457E-03 0,02008251 ! defense response to fungus GO:0050832 13 11 0,000 9,457E-03 0,0200648 ! lysogeny GO:0030069 21 11 0,000 9,457E-03 0,02004712 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 9,457E-03 0,02002948 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 9,457E-03 0,02001186 ! sequestering of metal ion GO:0051238 14 11 0,000 9,457E-03 0,01999428 ! lamellipodium assembly GO:0030032 20 11 0,000 9,457E-03 0,01997672 ! regulation of embryonic development GO:0045995 27 11 0,000 9,457E-03 0,0199592 ! nucleus localization GO:0051647 19 11 0,000 9,457E-03 0,0199417 ! regulation of synapse organization GO:0050807 17 11 0,000 9,457E-03 0,01992424 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01031242 0,02170752 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01031242 0,02168854 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01031242 0,0216696 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01031242 0,02165069 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01031242 0,02163182 ! virus-host interaction GO:0019048 29 12 0,000 0,01031242 0,02161297 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01031242 0,02159416 ! cartilage condensation GO:0001502 20 12 0,000 0,01031242 0,02157539 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01031242 0,02155664 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01031242 0,02153793 ! protein complex disassembly GO:0043241 27 12 0,000 0,01031242 0,02151925 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01031242 0,0215006 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01031242 0,02148199 ! hippocampus development GO:0021766 26 12 0,000 0,01031242 0,0214634 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01031242 0,02144485 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01031242 0,02142633 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01031242 0,02140785 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01031242 0,02138939 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01031242 0,02137097 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01031242 0,02135258 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01031242 0,02133422 ! drug transport GO:0015893 16 12 0,000 0,01031242 0,02131589 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01031242 0,02129759 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01031242 0,02127933 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01031242 0,02126109 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01031242 0,02124289 ! focal adhesion formation GO:0048041 35 12 0,000 0,01031242 0,02122472 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01031242 0,02120658 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01031242 0,02118847 ! forebrain cell migration GO:0021885 21 12 0,000 0,01031242 0,02117039 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01031242 0,02115234 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01031242 0,02113432 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01031242 0,02111633 ! entry into host cell GO:0030260 32 12 0,000 0,01031242 0,02109838 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01031242 0,02108045 ! monoamine transport GO:0015844 18 12 0,000 0,01031242 0,02106256 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01031242 0,02104469 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01031242 0,02102686 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01031242 0,02100905 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01031242 0,02099128 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01031242 0,02097354 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01031242 0,02095582 ! protein homotetramerization GO:0051289 21 12 0,000 0,01031242 0,02093814 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01031242 0,02092048 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01031242 0,02090286 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01031242 0,02088526 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01031242 0,0208677 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01031242 0,02085016 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01031242 0,02083266 ! cranial nerve development GO:0021545 20 12 0,000 0,01031242 0,02081518 ! fucose catabolic process GO:0019317 22 12 0,000 0,01031242 0,02079773 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01031242 0,02078031 ! histone acetylation GO:0016573 26 12 0,000 0,01031242 0,02076292 ! histone methylation GO:0016571 26 12 0,000 0,01031242 0,02074556 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01031242 0,02072823 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01031242 0,02071093 ! gland morphogenesis GO:0022612 29 12 0,000 0,01031242 0,02069366 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01031242 0,02067641 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01031242 0,02065919 ! T cell homeostasis GO:0043029 25 12 0,000 0,01031242 0,02064201 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01031242 0,02062485 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01031242 0,02060772 ! spleen development GO:0048536 22 12 0,000 0,01031242 0,02059062 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01031242 0,02057354 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01031242 0,0205565 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01031242 0,02053948 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01031242 0,02052249 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01031242 0,02050553 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01031242 0,0204886 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01031242 0,02047169 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01031242 0,02045482 ! response to cold GO:0009409 17 12 0,000 0,01031242 0,02043797 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01031242 0,02042115 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01031242 0,02040435 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01116716 0,0220774 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01116716 0,02205927 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01116716 0,02204117 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01116716 0,02202311 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01116716 0,02200507 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01116716 0,02198706 ! lipid localization GO:0010876 28 13 0,000 0,01116716 0,02196909 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,01116716 0,02195114 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01116716 0,02193322 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01116716 0,02191533 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01116716 0,02189747 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01116716 0,02187964 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01116716 0,02186183 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01116716 0,02184406 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01116716 0,02182631 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01116716 0,0218086 ! methionine metabolic process GO:0006555 27 13 0,000 0,01116716 0,02179091 ! plasma membrane organization GO:0007009 24 13 0,000 0,01116716 0,02177325 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01116716 0,02175562 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01116716 0,02173802 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01116716 0,02172045 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01116716 0,0217029 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01116716 0,02168538 ! response to X-ray GO:0010165 25 13 0,000 0,01116716 0,0216679 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01116716 0,02165044 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01116716 0,021633 ! exocrine system development GO:0035272 32 13 0,000 0,01116716 0,0216156 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01116716 0,02159822 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01116716 0,02158088 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01116716 0,02156356 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01116716 0,02154626 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01116716 0,021529 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01116716 0,02151176 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01116716 0,02149455 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01116716 0,02147737 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01116716 0,02146022 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01116716 0,02144309 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01116716 0,02142599 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01116716 0,02140892 ! ribosome assembly GO:0042255 17 13 0,000 0,01116716 0,02139187 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01116716 0,02137485 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01116716 0,02135786 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01116716 0,0213409 ! chromatin silencing GO:0006342 26 13 0,000 0,01116716 0,02132396 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01116716 0,02130705 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01116716 0,02129017 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01116716 0,02127331 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01116716 0,02125648 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01116716 0,02123968 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01116716 0,0212229 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01116716 0,02120615 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01116716 0,02118943 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01116716 0,02117273 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01116716 0,02115606 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01116716 0,02113941 ! embryonic placenta development GO:0001892 23 13 0,000 0,01116716 0,02112279 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01116716 0,0211062 ! insulin secretion GO:0030073 23 13 0,000 0,01116716 0,02108963 ! actin filament polymerization GO:0030041 24 13 0,000 0,01116716 0,02107309 ! acrosome reaction GO:0007340 18 13 0,000 0,01116716 0,02105658 ! rRNA transcription GO:0009303 25 14 0,000 0,01202119 0,02264916 ! lactation GO:0007595 26 14 0,000 0,01202119 0,02263144 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01202119 0,02261375 ! reproductive cellular process GO:0048610 20 14 0,000 0,01202119 0,02259608 ! tRNA modification GO:0006400 20 14 0,000 0,01202119 0,02257844 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01202119 0,02256083 ! regulation of S phase GO:0033261 23 14 0,000 0,01202119 0,02254324 ! water transport GO:0006833 21 14 0,000 0,01202119 0,02252569 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01202119 0,02250816 ! non-recombinational repair GO:0000726 25 14 0,000 0,01202119 0,02249066 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01202119 0,02247318 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01202119 0,02245573 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01202119 0,02243831 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01202119 0,02242092 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01202119 0,02240355 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01202119 0,02238621 ! palate development GO:0060021 31 14 0,000 0,01202119 0,0223689 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01202119 0,02235161 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01202119 0,02233435 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01202119 0,02231712 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01202119 0,02229991 ! arginine metabolic process GO:0006525 17 14 0,000 0,01202119 0,02228273 ! regulation of heart rate GO:0002027 24 14 0,000 0,01202119 0,02226558 ! organic alcohol transport GO:0015850 29 14 0,000 0,01202119 0,02224845 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01202119 0,02223135 ! embryo implantation GO:0007566 30 14 0,000 0,01202119 0,02221427 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01202119 0,02219722 ! L-amino acid transport GO:0015807 30 14 0,000 0,01202119 0,0221802 ! bone mineralization GO:0030282 17 14 0,000 0,01202119 0,02216321 ! stem cell development GO:0048864 43 14 0,000 0,01202119 0,02214623 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01202119 0,02212929 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01202119 0,02211237 ! cerebellum development GO:0021549 21 14 0,000 0,01202119 0,02209548 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01202119 0,02207861 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01202119 0,02206177 ! response to gamma radiation GO:0010332 28 14 0,000 0,01202119 0,02204496 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01202119 0,02202817 ! cofactor transport GO:0051181 26 14 0,000 0,01202119 0,0220114 ! NADP metabolic process GO:0006739 24 14 0,000 0,01202119 0,02199466 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01202119 0,02197795 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01202119 0,02196126 ! intestinal absorption GO:0050892 25 14 0,000 0,01202119 0,0219446 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01202119 0,02192796 ! oxygen transport GO:0015671 21 14 0,000 0,01202119 0,02191135 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01202119 0,02189476 ! male genitalia development GO:0030539 24 14 0,000 0,01202119 0,0218782 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01202119 0,02186167 ! regulation of axon extension GO:0030516 37 14 0,000 0,01202119 0,02184515 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01202119 0,02182867 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01287451 0,02336053 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01287451 0,02334293 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,01287451 0,02332535 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01287451 0,0233078 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01287451 0,02329028 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01287451 0,02327278 ! copper ion transport GO:0006825 20 15 0,000 0,01287451 0,02325531 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01287451 0,02323786 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01287451 0,02322044 ! sulfate transport GO:0008272 23 15 0,000 0,01287451 0,02320305 ! response to cAMP GO:0051591 22 15 0,000 0,01287451 0,02318568 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01287451 0,02316834 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01287451 0,02315102 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01287451 0,02313373 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01287451 0,02311647 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01287451 0,02309923 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01287451 0,02308202 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01287451 0,02306483 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01287451 0,02304767 ! pituitary gland development GO:0021983 29 15 0,000 0,01287451 0,02303053 ! vesicle coating GO:0006901 33 15 0,000 0,01287451 0,02301342 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01287451 0,02299634 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01287451 0,02297928 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01287451 0,02296224 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01287451 0,02294524 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01287451 0,02292825 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01287451 0,02291129 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01287451 0,02289436 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01287451 0,02287745 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01287451 0,02286057 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01287451 0,02284371 ! histone deacetylation GO:0016575 20 15 0,000 0,01287451 0,02282687 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01287451 0,02281006 ! tissue regeneration GO:0042246 26 15 0,000 0,01287451 0,02279328 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01287451 0,02277652 ! water homeostasis GO:0030104 27 15 0,000 0,01287451 0,02275978 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01287451 0,02274307 ! muscle maintenance GO:0046716 26 15 0,000 0,01287451 0,02272639 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01287451 0,02270973 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01287451 0,02269309 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01287451 0,02267648 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01287451 0,02265989 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01287451 0,02264332 ! cell killing GO:0001906 29 15 0,000 0,01287451 0,02262678 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01287451 0,02261027 ! detection of bacterium GO:0016045 18 15 0,000 0,01287451 0,02259378 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01287451 0,02257731 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01287451 0,02256086 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01287451 0,02254444 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01287451 0,02252805 ! peptide hormone processing GO:0016486 23 15 0,000 0,01287451 0,02251168 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,01372712 0,02398507 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01372712 0,02396767 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01372712 0,02395029 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01372712 0,02393293 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01372712 0,0239156 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01372712 0,0238983 ! bone remodeling GO:0046849 27 16 0,000 0,01372712 0,02388102 ! filopodium assembly GO:0046847 32 16 0,000 0,01372712 0,02386376 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01372712 0,02384653 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01372712 0,02382933 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01372712 0,02381215 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01372712 0,02379499 ! startle response GO:0001964 28 16 0,000 0,01372712 0,02377786 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01372712 0,02376075 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01372712 0,02374367 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01372712 0,02372661 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01372712 0,02370958 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01372712 0,02369257 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01372712 0,02367559 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01372712 0,02365863 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01372712 0,02364169 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01372712 0,02362478 ! response to osmotic stress GO:0006970 25 16 0,000 0,01372712 0,0236079 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01372712 0,02359103 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01372712 0,02357419 ! fructose metabolic process GO:0006000 25 16 0,000 0,01372712 0,02355738 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01372712 0,02354059 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01372712 0,02352382 ! intermediate filament-based process GO:0045103 32 16 0,000 0,01372712 0,02350708 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01372712 0,02349036 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01372712 0,02347367 ! axon cargo transport GO:0008088 43 16 0,000 0,01372712 0,02345699 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01372712 0,02344035 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01372712 0,02342372 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01372712 0,02340712 ! DNA replication initiation GO:0006270 27 16 0,000 0,01372712 0,02339054 ! neuron recognition GO:0008038 35 16 0,000 0,01372712 0,02337399 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01372712 0,02335746 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01372712 0,02334095 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01372712 0,02332447 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01372712 0,02330801 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01372712 0,02329157 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01372712 0,02327516 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01372712 0,02325877 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01372712 0,0232424 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01372712 0,02322605 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01372712 0,02320973 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01372712 0,02319343 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01372712 0,02317716 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01372712 0,0231609 ! defense response to virus GO:0051607 37 16 0,000 0,01372712 0,02314467 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01457902 0,02456381 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01457902 0,02454662 ! metencephalon development GO:0022037 30 17 0,000 0,01457902 0,02452946 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01457902 0,02451231 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01457902 0,0244952 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01457902 0,0244781 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01457902 0,02446103 ! signal complex assembly GO:0007172 41 17 0,000 0,01457902 0,02444399 ! endothelial cell migration GO:0043542 28 17 0,000 0,01457902 0,02442697 ! inositol metabolic process GO:0006020 28 17 0,000 0,01457902 0,02440997 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01457902 0,02439299 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01457902 0,02437604 ! glial cell development GO:0021782 27 17 0,000 0,01457902 0,02435911 ! limbic system development GO:0021761 36 17 0,000 0,01457902 0,02434221 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01457902 0,02432533 ! adult walking behavior GO:0007628 33 17 0,000 0,01457902 0,02430847 ! heart looping GO:0001947 30 17 0,000 0,01457902 0,02429164 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01457902 0,02427483 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01457902 0,02425804 ! myoblast differentiation GO:0045445 45 17 0,000 0,01457902 0,02424127 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01457902 0,02422453 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01457902 0,02420781 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01457902 0,02419112 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01457902 0,02417445 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01457902 0,0241578 ! glycine metabolic process GO:0006544 28 17 0,000 0,01457902 0,02414117 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01457902 0,02412457 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01457902 0,02410799 ! NAD metabolic process GO:0019674 29 17 0,000 0,01457902 0,02409143 ! membrane budding GO:0006900 37 17 0,000 0,01457902 0,0240749 ! DNA integration GO:0015074 29 17 0,000 0,01457902 0,02405838 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01457902 0,02404189 ! regulation of protein binding GO:0043393 33 17 0,000 0,01457902 0,02402543 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01457902 0,02400898 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01457902 0,02399256 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01457902 0,02397616 ! genitalia development GO:0048806 30 17 0,000 0,01457902 0,02395978 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01457902 0,02394343 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01457902 0,0239271 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01457902 0,02391079 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01457902 0,0238945 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01457902 0,02387823 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01457902 0,02386199 ! steroid catabolic process GO:0006706 31 17 0,000 0,01457902 0,02384577 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01457902 0,02382957 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01457902 0,02381339 ! gas transport GO:0015669 25 17 0,000 0,01457902 0,02379723 ! organic cation transport GO:0015695 31 17 0,000 0,01457902 0,0237811 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01457902 0,02376499 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01457902 0,0237489 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01457902 0,02373283 ! microspike assembly GO:0030035 36 17 0,000 0,01457902 0,02371678 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01457902 0,02370076 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01457902 0,02368476 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01543021 0,02505067 ! neuron maturation GO:0042551 42 18 0,000 0,01543021 0,02503378 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01543021 0,02501691 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01543021 0,02500006 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01543021 0,02498324 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01543021 0,02496644 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01543021 0,02494966 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01543021 0,02493291 ! memory GO:0007613 31 18 0,000 0,01543021 0,02491617 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01543021 0,02489946 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01543021 0,02488277 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01543021 0,02486611 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01543021 0,02484946 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01543021 0,02483284 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01543021 0,02481624 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01543021 0,02479966 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01543021 0,02478311 ! response to retinoic acid GO:0032526 26 18 0,000 0,01543021 0,02476657 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01543021 0,02475006 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01543021 0,02473357 ! response to fungus GO:0009620 21 18 0,000 0,01543021 0,02471711 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01543021 0,02470066 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01543021 0,02468424 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01543021 0,02466784 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01543021 0,02465146 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01543021 0,0246351 ! vitamin transport GO:0051180 27 18 0,000 0,01543021 0,02461876 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01543021 0,02460245 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01543021 0,02458616 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01543021 0,02456988 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01543021 0,02455363 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01543021 0,02453741 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01543021 0,0245212 ! nerve development GO:0021675 28 18 0,000 0,01543021 0,02450501 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01543021 0,02448885 ! protein secretion GO:0009306 39 19 0,000 0,0162807 0,0258216 ! positive regulation of translation GO:0045727 30 19 0,000 0,0162807 0,02580459 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0162807 0,0257876 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0162807 0,02577064 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0162807 0,02575369 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0162807 0,02573677 ! lipid phosphorylation GO:0046834 35 19 0,000 0,0162807 0,02571987 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0162807 0,025703 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0162807 0,02568614 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0162807 0,02566931 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0162807 0,0256525 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0162807 0,02563571 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0162807 0,02561895 ! cerebral cortex development GO:0021987 36 19 0,000 0,0162807 0,0256022 ! pigmentation during development GO:0048066 41 19 0,000 0,0162807 0,02558548 ! response to vitamin A GO:0033189 27 19 0,000 0,0162807 0,02556878 ! heme metabolic process GO:0042168 36 19 0,000 0,0162807 0,0255521 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0162807 0,02553544 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0162807 0,02551881 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0162807 0,02550219 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0162807 0,0254856 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0162807 0,02546903 ! peptide cross-linking GO:0018149 37 19 0,000 0,0162807 0,02545248 ! protein export from nucleus GO:0006611 36 19 0,000 0,0162807 0,02543595 ! heart process GO:0003015 30 19 0,000 0,0162807 0,02541945 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0162807 0,02540296 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0162807 0,0253865 ! visual learning GO:0008542 36 19 0,000 0,0162807 0,02537006 ! cellular pigmentation GO:0033059 36 19 0,000 0,0162807 0,02535364 ! G1 phase GO:0051318 40 19 0,000 0,0162807 0,02533724 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0162807 0,02532086 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0162807 0,0253045 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,0162807 0,02528817 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0162807 0,02527185 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0162807 0,02525556 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0162807 0,02523928 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0162807 0,02522303 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0162807 0,0252068 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0162807 0,02519059 ! cilium assembly GO:0042384 37 19 0,000 0,0162807 0,0251744 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0162807 0,02515823 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01713048 0,02645439 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01713048 0,02643742 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01713048 0,02642047 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01713048 0,02640355 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01713048 0,02638665 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01713048 0,02636976 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01713048 0,0263529 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01713048 0,02633606 ! response to vitamin GO:0033273 31 20 0,000 0,01713048 0,02631925 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01713048 0,02630245 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01713048 0,02628568 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01713048 0,02626892 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01713048 0,02625219 ! response to alkaloid GO:0043279 38 20 0,000 0,01713048 0,02623548 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01713048 0,02621879 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01713048 0,02620212 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01713048 0,02618548 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01713048 0,02616885 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01713048 0,02615225 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01713048 0,02613566 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01713048 0,0261191 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01713048 0,02610256 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01713048 0,02608604 ! body fluid secretion GO:0007589 31 20 0,000 0,01713048 0,02606954 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01713048 0,02605306 ! peptide secretion GO:0002790 35 20 0,000 0,01713048 0,0260366 ! stem cell differentiation GO:0048863 53 20 0,000 0,01713048 0,02602016 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01713048 0,02600375 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01713048 0,02598735 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01713048 0,02597098 ! sensory perception of pain GO:0019233 30 20 0,000 0,01713048 0,02595462 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01713048 0,02593829 ! diencephalon development GO:0021536 34 20 0,000 0,01713048 0,02592198 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01713048 0,02590568 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01713048 0,02588941 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01713048 0,02587316 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01713048 0,02585693 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01713048 0,02584071 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01713048 0,02582452 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01713048 0,02580835 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01713048 0,0257922 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01713048 0,02577607 ! regulation of glucose import GO:0046324 29 20 0,000 0,01713048 0,02575996 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01713048 0,02574387 ! actin filament-based movement GO:0030048 43 20 0,000 0,01713048 0,0257278 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01713048 0,02571175 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01713048 0,02569572 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01713048 0,02567971 ! negative regulation of translation GO:0017148 29 20 0,000 0,01713048 0,02566372 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01713048 0,02564775 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01713048 0,0256318 ! regulation of cell killing GO:0031341 42 21 0,000 0,01797956 0,02688553 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01797956 0,02686883 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01797956 0,02685215 ! hormone secretion GO:0046879 38 21 0,000 0,01797956 0,02683549 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01797956 0,02681886 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01797956 0,02680224 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01797956 0,02678564 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01797956 0,02676907 ! ovarian follicle development GO:0001541 35 21 0,000 0,01797956 0,02675251 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01797956 0,02673598 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01797956 0,02671947 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01797956 0,02670297 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01797956 0,0266865 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01797956 0,02667005 ! cell aging GO:0007569 44 21 0,000 0,01797956 0,02665361 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01797956 0,0266372 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01797956 0,02662081 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01797956 0,02660444 ! cytolysis GO:0019835 24 21 0,000 0,01797956 0,02658809 ! vasodilation GO:0042311 39 21 0,000 0,01797956 0,02657175 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01797956 0,02655544 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01797956 0,02653915 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,01797956 0,02652288 ! oogenesis GO:0048477 36 21 0,000 0,01797956 0,02650663 ! DNA modification GO:0006304 34 21 0,000 0,01797956 0,02649039 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01797956 0,02647418 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01797956 0,02645799 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01797956 0,02644182 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01797956 0,02642567 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01797956 0,02640953 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01797956 0,02639342 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01797956 0,02637733 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01797956 0,02636125 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01797956 0,0263452 ! collagen catabolic process GO:0030574 28 21 0,000 0,01797956 0,02632916 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01797956 0,02631315 ! gut development GO:0048565 39 21 0,000 0,01797956 0,02629715 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01882793 0,02752126 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01882793 0,02750455 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01882793 0,02748786 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01882793 0,02747119 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01882793 0,02745454 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01882793 0,02743791 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01882793 0,0274213 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01882793 0,02740471 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01882793 0,02738815 ! regeneration GO:0031099 41 22 0,000 0,01882793 0,0273716 ! keratinization GO:0031424 28 22 0,000 0,01882793 0,02735507 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01882793 0,02733856 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01882793 0,02732207 ! sensory perception of taste GO:0050909 28 22 0,000 0,01882793 0,0273056 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01882793 0,02728915 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01882793 0,02727272 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01882793 0,02725631 ! vacuolar transport GO:0007034 36 22 0,000 0,01882793 0,02723992 ! lysosome organization GO:0007040 41 22 0,000 0,01882793 0,02722355 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01882793 0,0272072 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01882793 0,02719087 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01882793 0,02717456 ! fucose metabolic process GO:0006004 39 22 0,000 0,01882793 0,02715827 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01882793 0,027142 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01882793 0,02712574 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01882793 0,02710951 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01882793 0,0270933 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01882793 0,0270771 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01882793 0,02706093 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01882793 0,02704477 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01882793 0,02702863 ! sarcomere organization GO:0045214 30 22 0,000 0,01882793 0,02701252 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01882793 0,02699642 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01882793 0,02698034 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01882793 0,02696428 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01882793 0,02694824 ! protein stabilization GO:0050821 39 22 0,000 0,01882793 0,02693222 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01967559 0,02812803 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01967559 0,02811133 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,01967559 0,02809464 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01967559 0,02807798 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01967559 0,02806134 ! gluconeogenesis GO:0006094 33 23 0,000 0,01967559 0,02804471 ! viral genome replication GO:0019079 41 23 0,000 0,01967559 0,02802811 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01967559 0,02801152 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01967559 0,02799496 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01967559 0,02797841 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01967559 0,02796189 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01967559 0,02794538 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01967559 0,02792889 ! visual behavior GO:0007632 42 23 0,000 0,01967559 0,02791243 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,01967559 0,02789598 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01967559 0,02787955 ! response to ethanol GO:0045471 46 23 0,000 0,01967559 0,02786314 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01967559 0,02784675 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01967559 0,02783038 ! peroxisome organization GO:0007031 37 23 0,000 0,01967559 0,02781403 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01967559 0,02779769 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01967559 0,02778138 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01967559 0,02776509 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01967559 0,02774881 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01967559 0,02773256 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01967559 0,02771632 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01967559 0,0277001 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01967559 0,0276839 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01967559 0,02766772 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01967559 0,02765156 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01967559 0,02763542 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01967559 0,0276193 ! fatty acid transport GO:0015908 44 23 0,000 0,01967559 0,02760319 ! platelet activation GO:0030168 37 23 0,000 0,01967559 0,02758711 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01967559 0,02757104 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01967559 0,02755499 ! hormone transport GO:0009914 40 23 0,000 0,01967559 0,02753896 ! cell-cell recognition GO:0009988 25 23 0,000 0,01967559 0,02752295 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01967559 0,02750696 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01967559 0,02749098 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01967559 0,02747503 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01967559 0,02745909 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01967559 0,02744317 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,02052255 0,02860791 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02052255 0,02859135 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,02052255 0,0285748 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,02052255 0,02855828 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02052255 0,02854177 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,02052255 0,02852528 ! vesicle docking GO:0048278 47 24 0,000 0,02052255 0,02850881 ! spinal cord development GO:0021510 47 24 0,000 0,02052255 0,02849236 ! vacuole organization GO:0007033 43 24 0,000 0,02052255 0,02847593 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02052255 0,02845952 ! digestive system process GO:0022600 39 24 0,000 0,02052255 0,02844312 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02052255 0,02842675 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02052255 0,02841039 ! regulation of behavior GO:0050795 43 24 0,000 0,02052255 0,02839405 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02052255 0,02837774 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02052255 0,02836144 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02052255 0,02834516 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02052255 0,02832889 ! membrane depolarization GO:0051899 39 24 0,000 0,02052255 0,02831265 ! pallium development GO:0021543 49 24 0,000 0,02052255 0,02829642 ! pentose metabolic process GO:0019321 35 24 0,000 0,02052255 0,02828022 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,02052255 0,02826403 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,02052255 0,02824786 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02052255 0,02823171 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02052255 0,02821558 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02052255 0,02819946 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02052255 0,02818337 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,02052255 0,02816729 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02052255 0,02815123 ! regulation of amine transport GO:0051952 40 24 0,000 0,02052255 0,02813519 ! protein tetramerization GO:0051262 52 24 0,000 0,02052255 0,02811917 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02136881 0,02926201 ! myelination GO:0042552 45 25 0,000 0,02136881 0,02924537 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02136881 0,02922874 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02136881 0,02921213 ! phototransduction GO:0007602 33 25 0,000 0,02136881 0,02919555 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02136881 0,02917898 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02136881 0,02916243 ! sperm motility GO:0030317 31 25 0,000 0,02136881 0,02914589 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02136881 0,02912938 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02136881 0,02911289 ! receptor metabolic process GO:0043112 46 25 0,000 0,02136881 0,02909641 ! chromosome condensation GO:0030261 45 25 0,000 0,02136881 0,02907995 ! response to starvation GO:0042594 42 25 0,000 0,02136881 0,02906351 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02136881 0,02904709 ! neural crest cell development GO:0014032 54 25 0,000 0,02136881 0,02903069 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02136881 0,02901431 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02136881 0,02899794 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02136881 0,0289816 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02136881 0,02896527 ! interaction with host GO:0051701 62 25 0,000 0,02136881 0,02894896 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02136881 0,02893267 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02136881 0,0289164 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02136881 0,02890014 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02136881 0,02888391 ! immunoglobulin production GO:0002377 55 25 0,000 0,02136881 0,02886769 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02136881 0,02885149 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02136881 0,02883531 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02136881 0,02881915 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02136881 0,028803 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02136881 0,02878687 ! telomere organization GO:0032200 43 25 0,000 0,02136881 0,02877076 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02136881 0,02875467 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,02136881 0,0287386 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02221436 0,02985908 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02221436 0,02984241 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02221436 0,02982576 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02221436 0,02980912 ! initiation of viral infection GO:0019059 57 26 0,000 0,02221436 0,02979251 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02221436 0,02977591 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02221436 0,02975933 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02221436 0,02974277 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02221436 0,02972623 ! molting cycle process GO:0022404 50 26 0,000 0,02221436 0,0297097 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,02221436 0,0296932 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,02221436 0,02967671 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,02221436 0,02966024 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,02221436 0,02964379 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,02221436 0,02962736 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,02221436 0,02961095 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,02221436 0,02959455 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,02221436 0,02957817 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02221436 0,02956181 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02221436 0,02954547 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02221436 0,02952915 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02221436 0,02951284 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,02221436 0,02949656 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02221436 0,02948029 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02221436 0,02946403 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02221436 0,0294478 ! blastocyst development GO:0001824 49 26 0,000 0,02221436 0,02943158 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02221436 0,02941539 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02221436 0,02939921 ! neuron fate commitment GO:0048663 48 27 0,000 0,02305921 0,03050053 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,02305921 0,03048378 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,02305921 0,03046704 ! iron ion transport GO:0006826 59 27 0,000 0,02305921 0,03045031 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,02305921 0,03043361 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,02305921 0,03041692 ! protein amino acid acylation GO:0043543 55 27 0,000 0,02305921 0,03040026 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,02305921 0,03038361 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,02305921 0,03036698 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,02305921 0,03035037 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,02305921 0,03033377 ! autophagy GO:0006914 41 27 0,000 0,02305921 0,0303172 ! male gonad development GO:0008584 44 27 0,000 0,02305921 0,03030064 ! response to toxin GO:0009636 47 27 0,000 0,02305921 0,0302841 ! primary neural tube formation GO:0014020 51 27 0,000 0,02305921 0,03026758 ! base-excision repair GO:0006284 41 27 0,000 0,02305921 0,03025107 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,02305921 0,03023459 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,02305921 0,03021812 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,02305921 0,03020167 ! glutathione metabolic process GO:0006749 39 27 0,000 0,02305921 0,03018524 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,02305921 0,03016883 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,02305921 0,03015243 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,02305921 0,03013605 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,02305921 0,03011969 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02390336 0,03120537 ! circadian rhythm GO:0007623 50 28 0,000 0,02390336 0,03118845 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02390336 0,03117154 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02390336 0,03115466 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,02390336 0,03113779 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02390336 0,03112094 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02390336 0,03110411 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02390336 0,03108729 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02390336 0,0310705 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02390336 0,03105372 ! synaptogenesis GO:0007416 42 28 0,000 0,02390336 0,03103696 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02390336 0,03102022 ! lipid oxidation GO:0034440 43 28 0,000 0,02390336 0,0310035 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02390336 0,0309868 ! translational initiation GO:0006413 65 29 0,000 0,02474681 0,03206291 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,02474681 0,03204566 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02474681 0,03202842 ! regulation of pH GO:0006885 43 29 0,000 0,02474681 0,0320112 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02474681 0,031994 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02474681 0,03197682 ! catechol metabolic process GO:0009712 54 29 0,000 0,02474681 0,03195965 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02474681 0,03194251 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02474681 0,03192538 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02474681 0,03190827 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02474681 0,03189118 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02474681 0,03187411 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02474681 0,03185705 ! cell fate determination GO:0001709 60 29 0,000 0,02474681 0,03184002 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02474681 0,031823 ! detection of light stimulus GO:0009583 38 29 0,000 0,02474681 0,031806 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,02474681 0,03178902 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,02474681 0,03177206 ! tissue homeostasis GO:0001894 48 29 0,000 0,02474681 0,03175511 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,02474681 0,03173818 ! phenol metabolic process GO:0018958 55 30 0,000 0,02558956 0,03280154 ! zinc ion transport GO:0006829 45 30 0,000 0,02558956 0,03278407 ! membrane docking GO:0022406 61 30 0,000 0,02558956 0,03276662 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02558956 0,03274919 ! cell junction assembly GO:0034329 78 30 0,000 0,02558956 0,03273178 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02558956 0,03271439 ! acute-phase response GO:0006953 49 30 0,000 0,02558956 0,03269702 ! myofibril assembly GO:0030239 47 30 0,000 0,02558956 0,03267966 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02558956 0,03266232 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02558956 0,03264501 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02558956 0,03262771 ! phospholipid transport GO:0015914 51 30 0,000 0,02558956 0,03261042 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02558956 0,03259316 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02558956 0,03257592 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02558956 0,03255869 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02558956 0,03254148 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02558956 0,03252429 ! eye morphogenesis GO:0048592 60 30 0,000 0,02558956 0,03250712 ! response to heat GO:0009408 50 30 0,000 0,02558956 0,03248996 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02643161 0,03354137 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02643161 0,03352369 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02643161 0,03350603 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02643161 0,03348839 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02643161 0,03347076 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02643161 0,03345315 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02643161 0,03343557 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02643161 0,033418 ! ovulation cycle process GO:0022602 49 31 0,000 0,02643161 0,03340044 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02643161 0,03338291 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02643161 0,0333654 ! peptide transport GO:0015833 55 31 0,000 0,02643161 0,0333479 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02643161 0,03333042 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02643161 0,03331296 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02643161 0,03329552 ! mesoderm formation GO:0001707 69 31 0,000 0,02643161 0,0332781 ! natural killer cell activation GO:0030101 45 31 0,000 0,02643161 0,03326069 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02643161 0,03324331 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02643161 0,03322594 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02643161 0,03320859 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02643161 0,03319126 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02643161 0,03317394 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02727295 0,03421206 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,02727295 0,03419423 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02727295 0,03417642 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02727295 0,03415863 ! cholesterol transport GO:0030301 56 32 0,000 0,02727295 0,03414086 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02727295 0,0341231 ! spliceosome assembly GO:0000245 67 32 0,000 0,02727295 0,03410537 ! spindle organization GO:0007051 46 32 0,000 0,02727295 0,03408765 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02727295 0,03406995 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02727295 0,03405227 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02727295 0,03403461 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02727295 0,03401697 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02727295 0,03399934 ! muscle cell development GO:0055001 49 32 0,000 0,02727295 0,03398173 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02727295 0,03396415 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02727295 0,03394657 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02727295 0,03392902 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02727295 0,03391149 ! ovulation cycle GO:0042698 51 32 0,000 0,02727295 0,03389397 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02727295 0,03387647 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02727295 0,03385899 ! hindbrain development GO:0030902 61 32 0,000 0,02727295 0,03384153 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02727295 0,03382409 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02727295 0,03380666 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02727295 0,03378925 ! gene silencing GO:0016458 65 32 0,000 0,02727295 0,03377186 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,0281136 0,03479492 ! post-embryonic development GO:0009791 69 33 0,000 0,0281136 0,03477703 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,0281136 0,03475916 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0281136 0,03474131 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0281136 0,03472347 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0281136 0,03470566 ! formation of primary germ layer GO:0001704 72 33 0,000 0,0281136 0,03468786 ! sterol transport GO:0015918 57 33 0,000 0,0281136 0,03467008 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0281136 0,03465232 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0281136 0,03463458 ! adult locomotory behavior GO:0008344 59 33 0,000 0,0281136 0,03461685 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0281136 0,03459914 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,02895355 0,03561465 ! glial cell differentiation GO:0010001 63 34 0,000 0,02895355 0,03559645 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,02895355 0,03557827 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,02895355 0,03556011 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,02895355 0,03554196 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,02895355 0,03552384 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,02895355 0,03550573 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,02895355 0,03548765 ! mismatch repair GO:0006298 46 34 0,000 0,02895355 0,03546958 ! spermatid development GO:0007286 63 34 0,000 0,02895355 0,03545153 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,02895355 0,03543349 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,02895355 0,03541548 ! placenta development GO:0001890 53 34 0,000 0,02895355 0,03539748 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,02895355 0,03537951 ! regulation of muscle development GO:0048634 70 35 0,000 0,0297928 0,03638654 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,0297928 0,03636808 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0297928 0,03634964 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,0297928 0,03633121 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0297928 0,03631281 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0297928 0,03629442 ! odontogenesis GO:0042476 66 35 0,000 0,0297928 0,03627606 ! female gonad development GO:0008585 58 35 0,000 0,0297928 0,03625771 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,0297928 0,03623938 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,0297928 0,03622106 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,0297928 0,03620277 ! cytokine production GO:0001816 59 35 0,000 0,0297928 0,0361845 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,0297928 0,03616624 ! neural tube formation GO:0001841 67 35 0,000 0,0297928 0,036148 ! vesicle localization GO:0051648 64 35 0,000 0,0297928 0,03612978 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,03063136 0,03712798 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,03063136 0,03710929 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03063136 0,03709061 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03063136 0,03707196 ! cell junction organization GO:0034330 86 36 0,000 0,03063136 0,03705332 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03063136 0,0370347 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03063136 0,0370161 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03063136 0,03699751 ! regulation of proteolysis GO:0030162 72 36 0,000 0,03063136 0,03697895 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03063136 0,03696041 ! aerobic respiration GO:0009060 55 36 0,000 0,03063136 0,03694188 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,03063136 0,03692337 ! embryonic organ development GO:0048568 57 36 0,000 0,03063136 0,03690488 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,03063136 0,03688641 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03063136 0,03686796 ! RNA export from nucleus GO:0006405 56 37 0,000 0,03146922 0,03785747 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,03146922 0,03783855 ! meiosis I GO:0007127 65 37 0,000 0,03146922 0,03781965 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,03146922 0,03780077 ! sister chromatid segregation GO:0000819 58 37 0,000 0,03146922 0,0377819 ! actomyosin structure organization GO:0031032 62 37 0,000 0,03146922 0,03776306 ! organic anion transport GO:0015711 68 37 0,000 0,03146922 0,03774423 ! tissue remodeling GO:0048771 76 37 0,000 0,03146922 0,03772543 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03146922 0,03770664 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03146922 0,03768787 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03146922 0,03766912 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03146922 0,03765039 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03146922 0,03763168 ! glycogen metabolic process GO:0005977 61 37 0,000 0,03146922 0,03761298 ! pigment metabolic process GO:0042440 80 37 0,000 0,03146922 0,03759431 ! spermatid differentiation GO:0048515 66 37 0,000 0,03146922 0,03757565 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,03146922 0,03755701 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,03230638 0,03853701 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,03230638 0,03851791 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,03230638 0,03849883 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,03230638 0,03847977 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,03230638 0,03846073 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,03230638 0,03844171 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,03230638 0,03842271 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,03230638 0,03840373 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,03230638 0,03838476 ! lipid homeostasis GO:0055088 67 38 0,000 0,03230638 0,03836582 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,03230638 0,03834689 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,03230638 0,03832798 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,03230638 0,03830909 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,03230638 0,03829022 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,03230638 0,03827136 ! glucan metabolic process GO:0044042 62 38 0,000 0,03230638 0,03825253 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,03314284 0,03922365 ! mammary gland development GO:0030879 86 39 0,000 0,03314284 0,03920436 ! learning GO:0007612 77 39 0,000 0,03314284 0,0391851 ! organic ether metabolic process GO:0018904 55 39 0,000 0,03314284 0,03916585 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,03314284 0,03914663 ! segmentation GO:0035282 67 39 0,000 0,03314284 0,03912742 ! ion transmembrane transport GO:0034220 66 39 0,000 0,03314284 0,03910823 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,03314284 0,03908906 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,03314284 0,03906991 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,03314284 0,03905077 ! RNA modification GO:0009451 57 39 0,000 0,03314284 0,03903166 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,03314284 0,03901256 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,03397861 0,03997679 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,03397861 0,03995725 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,03397861 0,03993773 ! feeding behavior GO:0007631 59 40 0,000 0,03397861 0,03991823 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,03397861 0,03989875 ! mesenchymal cell development GO:0014031 87 40 0,000 0,03397861 0,03987929 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,03397861 0,03985984 ! cytokinesis GO:0000910 72 40 0,000 0,03397861 0,03984042 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03481369 0,04079967 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03481369 0,04077981 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03481369 0,04075997 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03481369 0,04074014 ! gliogenesis GO:0042063 88 41 0,000 0,03481369 0,04072034 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03481369 0,04070055 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03481369 0,04068078 ! T cell differentiation GO:0030217 81 41 0,000 0,03481369 0,04066103 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03481369 0,04064131 ! female gamete generation GO:0007292 61 41 0,000 0,03481369 0,0406216 ! polyol metabolic process GO:0019751 66 41 0,000 0,03481369 0,04060191 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,03564807 0,04155487 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,03564807 0,04153475 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,03564807 0,04151464 ! regulation of tube size GO:0035150 71 42 0,000 0,03564807 0,04149456 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,03564807 0,04147449 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,03564807 0,04145445 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,03564807 0,04143442 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,03564807 0,04141441 ! neuron migration GO:0001764 79 42 0,000 0,03564807 0,04139443 ! regulation of protein secretion GO:0050708 71 42 0,000 0,03564807 0,04137446 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,03564807 0,04135451 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,03648176 0,04230125 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,03648176 0,04228088 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,03648176 0,04226052 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,03648176 0,04224018 ! glucose transport GO:0015758 65 43 0,000 0,03648176 0,04221987 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,03648176 0,04219957 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,03648176 0,04217929 ! neural tube development GO:0021915 77 43 0,000 0,03648176 0,04215903 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,03648176 0,04213879 ! striated muscle contraction GO:0006941 77 43 0,000 0,03648176 0,04211857 ! phagocytosis GO:0006909 90 43 0,000 0,03648176 0,04209837 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,03648176 0,04207819 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,03731475 0,04301835 ! hexose transport GO:0008645 67 44 0,000 0,03731475 0,04299774 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,03731475 0,04297716 ! male sex differentiation GO:0046661 76 44 0,000 0,03731475 0,0429566 ! double-strand break repair GO:0006302 81 44 0,000 0,03731475 0,04293605 ! biopolymer methylation GO:0043414 84 44 0,000 0,03731475 0,04291553 ! B cell differentiation GO:0030183 107 44 0,000 0,03731475 0,04289503 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,03731475 0,04287454 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,03731475 0,04285408 ! developmental growth GO:0048589 82 44 0,000 0,03731475 0,04283363 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,03814705 0,04376815 ! glycolysis GO:0006096 65 45 0,000 0,03814705 0,04374729 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,03814705 0,04372644 ! leukocyte migration GO:0050900 68 45 0,000 0,03814705 0,04370562 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,03814705 0,04368482 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,03814705 0,04366404 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,03814705 0,04364327 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,03814705 0,04362253 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,03814705 0,04360181 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,03814705 0,0435811 ! cell growth GO:0016049 84 45 0,000 0,03814705 0,04356042 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,03897866 0,04448893 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,03897866 0,04446783 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,03897866 0,04444676 ! pigmentation GO:0043473 100 46 0,000 0,03897866 0,0444257 ! response to insulin stimulus GO:0032868 95 46 0,000 0,03897866 0,04440467 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,03897866 0,04438365 ! positive regulation of defense response GO:0031349 76 47 0,000 0,03980958 0,04530835 ! endosome transport GO:0016197 108 47 0,000 0,03980958 0,04528693 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,03980958 0,04526552 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,03980958 0,04524414 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,03980958 0,04522278 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,03980958 0,04520144 ! methylation GO:0032259 90 47 0,000 0,03980958 0,04518012 ! protein homooligomerization GO:0051260 76 47 0,000 0,03980958 0,04515882 ! mitochondrial transport GO:0006839 82 48 0,000 0,04063981 0,04607888 ! Notch signaling pathway GO:0007219 96 48 0,000 0,04063981 0,04605717 ! cellular component disassembly GO:0022411 86 48 0,000 0,04063981 0,04603549 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,04063981 0,04601383 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,04063981 0,04599218 ! activation of caspase activity GO:0006919 84 48 0,000 0,04063981 0,04597056 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,04063981 0,04594896 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,04063981 0,04592737 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,04063981 0,04590581 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,04146935 0,04682086 ! regulation of action potential GO:0001508 95 49 0,000 0,04146935 0,0467989 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,04146935 0,04677696 ! regulation of ion transport GO:0043269 77 49 0,000 0,04146935 0,04675504 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,04146935 0,04673314 ! peptide metabolic process GO:0006518 76 49 0,000 0,04146935 0,04671126 ! response to temperature stimulus GO:0009266 76 49 0,000 0,04146935 0,0466894 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,04146935 0,04666756 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,04146935 0,04664574 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,04146935 0,04662395 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,04146935 0,04660217 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,04146935 0,04658041 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,04229819 0,04748925 ! neuromuscular process GO:0050905 99 50 0,000 0,04229819 0,0474671 ! regulation of ossification GO:0030278 117 50 0,000 0,04229819 0,04744497 ! histone modification GO:0016570 91 50 0,000 0,04229819 0,04742286 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,04229819 0,04740077 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,04229819 0,0473787 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,04229819 0,04735666 ! positive regulation of binding GO:0051099 78 51 0,000 0,04312635 0,0482614 ! viral infectious cycle GO:0019058 99 51 0,000 0,04312635 0,04823896 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,04312635 0,04821654 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,04312635 0,04819415 ! excretion GO:0007588 83 51 0,000 0,04312635 0,04817177 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,04312635 0,04814942 ! chromatin remodeling GO:0006338 109 51 0,000 0,04312635 0,04812709 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,04312635 0,04810478 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,04312635 0,04808249 ! vesicle organization GO:0016050 107 51 0,000 0,04312635 0,04806021 ! regulation of cell shape GO:0008360 125 51 0,000 0,04312635 0,04803796 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,04395382 0,04893702 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,04395382 0,04891438 ! membrane fusion GO:0006944 110 52 0,000 0,04395382 0,04889177 ! covalent chromatin modification GO:0016569 101 52 0,000 0,04395382 0,04886918 ! amino acid activation GO:0043038 92 52 0,000 0,04395382 0,0488466 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,04395382 0,04882405 ! synapse organization GO:0050808 85 52 0,000 0,04395382 0,04880152 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,0447806 0,04969656 ! RNA catabolic process GO:0006401 93 53 0,000 0,0447806 0,04967364 ! regulation of translational initiation GO:0006446 82 53 0,000 0,0447806 0,04965075 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,0447806 0,04962788 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,0447806 0,04960503 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,0447806 0,04958221 ! cell maturation GO:0048469 100 53 0,000 0,0447806 0,0495594 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,0447806 0,04953661 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,0447806 0,04951385 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,0456067 0,0504041 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,0456067 0,05038095 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,0456067 0,05035783 ! cell recognition GO:0008037 85 54 0,000 0,0456067 0,05033473 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,0456067 0,05031165 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,0456067 0,0502886 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,0456067 0,05026556 ! chloride transport GO:0006821 90 55 0,000 0,04643211 0,05115185 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,04643211 0,05112844 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,04643211 0,05110505 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,04643211 0,05108169 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,04643211 0,05105834 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,04643211 0,05103501 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,04643211 0,05101171 ! aging GO:0007568 103 55 0,000 0,04643211 0,05098843 ! gastrulation GO:0007369 112 55 0,000 0,04643211 0,05096517 ! heart morphogenesis GO:0003007 97 55 0,000 0,04643211 0,05094193 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,04643211 0,05091871 ! RNA elongation GO:0006354 79 55 0,000 0,04643211 0,05089551 ! nuclear export GO:0051168 97 55 0,000 0,04643211 0,05087233 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,04643211 0,05084918 ! regulation of actin filament length GO:0030832 105 56 0,000 0,04725683 0,05172881 ! sensory perception of smell GO:0007608 80 56 0,000 0,04725683 0,05170529 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,04725683 0,05168178 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,04725683 0,0516583 ! regulation of DNA replication GO:0006275 101 56 0,000 0,04725683 0,05163484 ! proton transport GO:0015992 94 56 0,000 0,04725683 0,05161141 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,04725683 0,05158799 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,04808086 0,05246374 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,04808086 0,05243996 ! lipid modification GO:0030258 97 57 0,000 0,04808086 0,0524162 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,04808086 0,05239246 ! hydrogen transport GO:0006818 97 58 0,000 0,04890421 0,05326552 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,04890421 0,05324142 ! regulation of endocytosis GO:0030100 91 58 0,000 0,04890421 0,05321734 ! adult behavior GO:0030534 99 58 0,000 0,04890421 0,05319328 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,04890421 0,05316924 ! positive regulation of secretion GO:0051047 95 59 0,000 0,04972688 0,05403924 ! regulation of cellular component size GO:0032535 109 59 0,000 0,04972688 0,05401484 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,04972688 0,05399046 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,04972688 0,05396611 ! DNA catabolic process GO:0006308 86 59 0,000 0,04972688 0,05394178 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,04972688 0,05391747 ! establishment of organelle localization GO:0051656 109 59 0,000 0,04972688 0,05389318 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,05054886 0,05475937 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,05054886 0,05473472 ! regulation of heart contraction GO:0008016 110 60 0,000 0,05054886 0,0547101 ! camera-type eye development GO:0043010 116 60 0,000 0,05054886 0,0546855 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,05054886 0,05466092 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,05054886 0,05463637 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,05137016 0,05549914 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,05137016 0,05547423 ! mesoderm development GO:0007498 119 61 0,000 0,05137016 0,05544935 ! tRNA processing GO:0008033 89 61 0,000 0,05137016 0,05542448 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,05137016 0,05539964 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,05137016 0,05537482 ! viral reproductive process GO:0022415 126 62 0,000 0,05219077 0,05623421 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,05219077 0,05620904 ! gonad development GO:0008406 98 62 0,000 0,05219077 0,05618389 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,05219077 0,05615876 ! regulation of mitosis GO:0007088 105 63 0,000 0,0530107 0,05701553 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,0530107 0,05699006 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,0530107 0,0569646 ! detection of external stimulus GO:0009581 91 63 0,000 0,0530107 0,05693917 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,0530107 0,05691376 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,0530107 0,05688838 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,05382995 0,0577418 ! cell redox homeostasis GO:0045454 102 64 0,000 0,05382995 0,05771607 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,05382995 0,05769036 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,05382995 0,05766468 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,05382995 0,05763901 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,05382995 0,05761337 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,05464852 0,05846347 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,05464852 0,05843748 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,05464852 0,05841152 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,05464852 0,05838558 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,05464852 0,05835967 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,05546641 0,05920682 ! actin filament organization GO:0007015 148 66 0,000 0,05546641 0,05918056 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,05546641 0,05915433 ! extracellular matrix organization GO:0030198 133 66 0,000 0,05546641 0,05912812 ! secondary metabolic process GO:0019748 116 66 0,000 0,05546641 0,05910194 ! developmental maturation GO:0021700 116 66 0,000 0,05546641 0,05907577 ! cell projection assembly GO:0030031 120 66 0,000 0,05546641 0,05904963 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,05628361 0,05989313 ! lung development GO:0030324 144 67 0,000 0,05628361 0,05986665 ! chromosome segregation GO:0007059 113 67 0,000 0,05628361 0,0598402 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,05628361 0,05981377 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,05628361 0,05978736 ! hexose catabolic process GO:0019320 104 67 0,000 0,05628361 0,05976098 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,05628361 0,05973461 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,05628361 0,05970828 ! adaptive immune response GO:0002250 119 67 0,000 0,05628361 0,05968196 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,05628361 0,05965567 ! amino acid transport GO:0006865 125 68 0,000 0,05710014 0,06049447 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,05710014 0,06046784 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,05710014 0,06044124 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,05710014 0,06041466 ! viral reproduction GO:0016032 134 68 0,000 0,05710014 0,0603881 ! regulation of lipase activity GO:0060191 130 68 0,000 0,05710014 0,06036157 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,05710014 0,06033506 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,05791599 0,06117026 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,05791599 0,06114342 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,05791599 0,06111661 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,05791599 0,06108981 ! antigen processing and presentation GO:0019882 104 69 0,000 0,05791599 0,06106304 ! appendage morphogenesis GO:0035107 135 70 0,000 0,05873115 0,06189538 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,05873115 0,06186828 ! amine catabolic process GO:0009310 117 71 0,000 0,05954564 0,06269883 ! reproductive structure development GO:0048608 113 71 0,000 0,05954564 0,0626714 ! appendage development GO:0048736 136 71 0,000 0,05954564 0,062644 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,05954564 0,06261662 ! B cell activation GO:0042113 160 71 0,000 0,05954564 0,06258926 ! regulation of immune effector process GO:0002697 137 71 0,000 0,05954564 0,06256193 ! acute inflammatory response GO:0002526 113 72 0,000 0,06035946 0,06338929 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,06035946 0,06336163 ! carbohydrate transport GO:0008643 110 72 0,000 0,06035946 0,063334 ! respiratory system development GO:0060541 153 72 0,000 0,06035946 0,06330639 ! learning or memory GO:0007611 147 73 0,000 0,06117259 0,06413127 ! regulation of blood pressure GO:0008217 125 73 0,000 0,06117259 0,06410334 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,06117259 0,06407543 ! axon guidance GO:0007411 139 73 0,000 0,06117259 0,06404754 ! fertilization GO:0009566 90 73 0,000 0,06117259 0,06401969 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,06198505 0,06484175 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,06198505 0,06481357 ! neurotransmitter transport GO:0006836 123 74 0,000 0,06198505 0,06478542 ! meiosis GO:0007126 121 74 0,000 0,06198505 0,06475729 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,06198505 0,06472918 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,06198505 0,0647011 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,06198505 0,06467304 ! eye development GO:0001654 143 74 0,000 0,06198505 0,06464501 ! organelle localization GO:0051640 136 74 0,000 0,06198505 0,064617 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,06279683 0,0654349 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,06279683 0,06540657 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,06279683 0,06537827 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,06279683 0,06534999 ! meiotic cell cycle GO:0051321 122 75 0,000 0,06279683 0,06532174 ! rhythmic process GO:0048511 128 75 0,000 0,06279683 0,06529351 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,06279683 0,06526531 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,06360794 0,06607975 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,06360794 0,06605123 ! defense response to bacterium GO:0042742 89 76 0,000 0,06360794 0,06602274 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,06360794 0,06599427 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,06360794 0,06596582 ! regulation of catabolic process GO:0009894 161 76 0,000 0,06360794 0,0659374 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,06441837 0,06674875 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,06441837 0,06672002 ! blood coagulation GO:0007596 146 78 0,000 0,06522813 0,06752964 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,06522813 0,0675006 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,06522813 0,06747158 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,06522813 0,06744258 ! protein oligomerization GO:0051259 139 78 0,000 0,06522813 0,06741361 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,06603722 0,0682205 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,06603722 0,06819122 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,06603722 0,06816196 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,06603722 0,06813274 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,06684563 0,06893724 ! muscle cell differentiation GO:0042692 159 80 0,000 0,06684563 0,0689077 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,06684563 0,06887819 ! protein import into nucleus GO:0006606 158 80 0,000 0,06684563 0,06884871 ! inorganic anion transport GO:0015698 138 80 0,000 0,06684563 0,06881924 ! T cell activation GO:0042110 168 81 0,000 0,06765336 0,06962104 ! response to hypoxia GO:0001666 171 81 0,000 0,06765336 0,06959127 ! digestion GO:0007586 112 81 0,000 0,06765336 0,06956153 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,06765336 0,06953182 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,06765336 0,06950213 ! nuclear import GO:0051170 161 81 0,000 0,06765336 0,06947247 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,06846043 0,07027124 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,06846043 0,07024128 ! response to drug GO:0042493 143 82 0,000 0,06846043 0,07021133 ! response to nutrient GO:0007584 125 82 0,000 0,06846043 0,07018142 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,06846043 0,07015153 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,06846043 0,07012166 ! response to oxygen levels GO:0070482 176 83 0,000 0,06926682 0,07091744 ! regulation of lyase activity GO:0051339 160 83 0,000 0,06926682 0,07088727 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,07007254 0,07168135 ! hemostasis GO:0007599 158 84 0,000 0,07007254 0,07165089 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,07007254 0,07162045 ! nucleosome assembly GO:0006334 122 85 0,000 0,0708776 0,07241252 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,0708776 0,07238179 ! amine biosynthetic process GO:0009309 138 86 0,000 0,07168198 0,07317218 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,07168198 0,07314115 ! chromatin assembly GO:0031497 124 86 0,000 0,07168198 0,07311015 ! alcohol catabolic process GO:0046164 130 86 0,000 0,07168198 0,07307917 ! amine transport GO:0015837 155 86 0,000 0,07168198 0,07304822 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,07248569 0,07383597 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,07248569 0,07380473 ! protein localization in nucleus GO:0034504 176 87 0,000 0,07248569 0,07377351 ! cellular respiration GO:0045333 135 88 0,000 0,07328873 0,07455928 ! regulation of neurological system process GO:0031644 148 88 0,000 0,07328873 0,07452776 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,07328873 0,07449628 ! cellular defense response GO:0006968 114 89 0,000 0,07409111 0,07528007 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,07409111 0,07524829 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,07409111 0,07521654 ! ossification GO:0001503 188 90 0,000 0,07489281 0,07599836 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,07489281 0,07596632 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,07489281 0,0759343 ! sex differentiation GO:0007548 145 90 0,000 0,07489281 0,07590232 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,07489281 0,07587036 ! bone development GO:0060348 189 91 0,000 0,07569385 0,07664958 ! sterol metabolic process GO:0016125 152 91 0,000 0,07569385 0,07661733 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,07569385 0,07658512 ! regulation of defense response GO:0031347 149 92 0,000 0,07649422 0,07736238 ! nucleosome organization GO:0034728 138 92 0,000 0,07649422 0,07732987 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,07649422 0,0772974 ! vitamin metabolic process GO:0006766 139 92 0,000 0,07649422 0,07726494 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,07729393 0,07803995 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,07729393 0,07800721 ! regulation of membrane potential GO:0042391 164 93 0,000 0,07729393 0,0779745 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,07729393 0,07794182 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,07809297 0,07871457 ! female pregnancy GO:0007565 164 94 0,000 0,07809297 0,07868161 ! transcription initiation GO:0006352 153 94 0,000 0,07809297 0,07864867 ! regulation of T cell activation GO:0050863 158 94 0,000 0,07809297 0,07861576 ! forebrain development GO:0030900 188 95 0,000 0,07889134 0,07938627 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,07889134 0,07935308 ! leukocyte differentiation GO:0002521 202 96 0,000 0,07968905 0,08012196 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,07968905 0,08008849 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,07968905 0,08005505 ! positive regulation of immune response GO:0050778 156 96 0,000 0,07968905 0,08002164 ! detection of stimulus GO:0051606 151 96 0,000 0,07968905 0,07998826 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,08048609 0,08075461 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,08048609 0,08072094 ! protein ubiquitination GO:0016567 217 97 0,000 0,08048609 0,08068731 ! hormone metabolic process GO:0042445 157 97 0,000 0,08048609 0,0806537 ! response to virus GO:0009615 160 98 0,000 0,08128248 0,08141783 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,08128248 0,08138395 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,08128248 0,0813501 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,08207819 0,08211232 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,08207819 0,08207819