pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/2932-3-real-Zhang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 6,293E-08 1,447E-04 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 5,392E-07 6,2E-04 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 7,173E-07 5,499E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 4,951E-06 2,847E-03 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 5,947E-06 2,736E-03 ! anagen GO:0042640 6 5 1,000 5,947E-06 2,28E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 5 1,000 5,947E-06 1,954E-03 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 5,947E-06 1,71E-03 GO:0007439|ectodermal gut development, ! response to UV GO:0009411 75 46 2,000 6,081E-06 1,554E-03 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 8,917E-06 2,051E-03 ! ER overload response GO:0006983 7 6 1,000 8,917E-06 1,864E-03 ! hair follicle maturation GO:0048820 7 6 1,000 8,917E-06 1,709E-03 ! regulation of myoblast differentiation GO:0045661 8 6 1,000 8,917E-06 1,578E-03 ! regulation of epidermal cell differentiation GO:0045604 7 6 1,000 8,917E-06 1,465E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,248E-05 1,913E-03 ! negative regulation of muscle cell differentiation GO:0051148 9 7 1,000 1,248E-05 1,794E-03 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 1,248E-05 1,688E-03 ! positive regulation of epidermis development GO:0045684 11 7 1,000 1,248E-05 1,594E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 1,663E-05 2,013E-03 ! keratinocyte proliferation GO:0043616 12 8 1,000 1,663E-05 1,912E-03 ! positive regulation of Ras GTPase activity GO:0032320 20 8 1,000 1,663E-05 1,821E-03 ! positive regulation of GTPase activity GO:0043547 21 9 1,000 2,137E-05 2,234E-03 ! endoderm development GO:0007492 12 9 1,000 2,137E-05 2,137E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 2,137E-05 2,048E-03 ! regulation of stress fiber formation GO:0051492 20 9 1,000 2,137E-05 1,966E-03 ! phosphoinositide-mediated signaling GO:0048015 109 71 2,000 2,263E-05 2,002E-03 ! regulation of phosphatase activity GO:0010921 21 10 1,000 2,67E-05 2,275E-03 ! hair follicle morphogenesis GO:0031069 17 10 1,000 2,67E-05 2,193E-03 ! UV protection GO:0009650 14 10 1,000 2,67E-05 2,118E-03 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 2,67E-05 2,047E-03 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 3,262E-05 2,42E-03 ! digestive tract morphogenesis GO:0048546 15 11 1,000 3,262E-05 2,345E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! positive regulation of cell growth GO:0030307 16 12 1,000 3,913E-05 2,727E-03 ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 3,913E-05 2,647E-03 ! regulation of epidermis development GO:0045682 17 12 1,000 3,913E-05 2,571E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 4,023E-05 2,57E-03 ! interphase GO:0051325 159 88 2,000 4,31E-05 2,679E-03 ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 5,39E-05 3,262E-03 ! epidermis morphogenesis GO:0048730 29 14 1,000 5,39E-05 3,179E-03 ! negative regulation of caspase activity GO:0043154 20 14 1,000 5,39E-05 3,099E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 5,39E-05 3,024E-03 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 5,39E-05 2,952E-03 ! response to light stimulus GO:0009416 153 96 2,000 5,59E-05 2,99E-03 ! regulation of protein ubiquitination GO:0031396 19 15 1,000 6,216E-05 3,249E-03 ! positive regulation of cell size GO:0045793 20 15 1,000 6,216E-05 3,177E-03 ! skin development GO:0043588 25 15 1,000 6,216E-05 3,108E-03 ! embryonic hindlimb morphogenesis GO:0035116 25 15 1,000 6,216E-05 3,042E-03 ! regulation of muscle cell differentiation GO:0051147 24 15 1,000 6,216E-05 2,979E-03 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 6,216E-05 2,918E-03 ! cellular response to unfolded protein GO:0034620 19 16 1,000 7,101E-05 3,266E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 33 16 1,000 7,101E-05 3,202E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 1,000 7,101E-05 3,141E-03 ! negative regulation of translation GO:0017148 22 16 1,000 7,101E-05 3,082E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 8,044E-05 3,426E-03 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 8,044E-05 3,364E-03 ! peptidyl-serine modification GO:0018209 27 17 1,000 8,044E-05 3,304E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 9,045E-05 3,65E-03 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 9,045E-05 3,587E-03 ! gut development GO:0048565 26 18 1,000 9,045E-05 3,526E-03 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 1,01E-04 3,874E-03 ! hindlimb morphogenesis GO:0035137 32 20 1,000 1,122E-04 4,231E-03 ! determination of left/right symmetry GO:0007368 23 20 1,000 1,122E-04 4,163E-03 ! determination of bilateral symmetry GO:0009855 25 21 1,000 1,24E-04 4,526E-03 GO:0009799|determination of symmetry, ! molting cycle process GO:0022404 40 22 1,000 1,363E-04 4,899E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 1,363E-04 4,824E-03 GO:0010810|regulation of cell-substrate adhesion, ! neuron fate commitment GO:0048663 32 23 1,000 1,492E-04 5,2E-03 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 1,492E-04 5,123E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 1,492E-04 5,048E-03 ! fat cell differentiation GO:0045444 37 24 1,000 1,627E-04 5,424E-03 ! base-excision repair GO:0006284 31 24 1,000 1,627E-04 5,347E-03 ! negative regulation of protein modification process GO:0031400 50 26 1,000 1,914E-04 6,201E-03 ! glial cell differentiation GO:0010001 55 31 1,000 2,733E-04 8,73E-03 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 2,733E-04 8,61E-03 ! cell fate specification GO:0001708 37 31 1,000 2,733E-04 8,494E-03 ! regulation of muscle development GO:0048634 48 32 1,000 2,914E-04 8,935E-03 ! RNA export from nucleus GO:0006405 44 33 1,000 3,1E-04 9,382E-03 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 3,1E-04 9,26E-03 ! Notch signaling pathway GO:0007219 56 35 1,000 3,49E-04 0,01029213 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 3,49E-04 0,01016185 ! keratinocyte differentiation GO:0030216 47 35 1,000 3,49E-04 0,01003482 ! glycogen metabolic process GO:0005977 48 35 1,000 3,49E-04 9,911E-03 ! glucan metabolic process GO:0044042 49 36 1,000 3,694E-04 0,01036122 GO:0006073|cellular glucan metabolic process, ! gliogenesis GO:0042063 71 38 1,000 4,118E-04 0,01141205 ! mesenchymal cell development GO:0014031 64 38 1,000 4,118E-04 0,0112762 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 4,339E-04 0,01174052 ! developmental growth GO:0048589 62 39 1,000 4,339E-04 0,011604 ! response to calcium ion GO:0051592 58 40 1,000 4,565E-04 0,01206881 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 4,565E-04 0,01193167 ! double-strand break repair GO:0006302 67 40 1,000 4,565E-04 0,0117976 ! epidermal cell differentiation GO:0009913 53 40 1,000 4,565E-04 0,01166652 ! positive regulation of protein transport GO:0051222 55 40 1,000 4,565E-04 0,01153832 ! energy reserve metabolic process GO:0006112 59 41 1,000 4,797E-04 0,01199269 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 5,035E-04 0,01245122 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 5,035E-04 0,01231876 ! response to insulin stimulus GO:0032868 63 43 1,000 5,278E-04 0,01277783 ! positive regulation of cell cycle GO:0045787 77 45 1,000 5,781E-04 0,01385032 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 6,578E-04 0,01559686 ! regulation of DNA replication GO:0006275 75 48 1,000 6,578E-04 0,0154377 ! nuclear export GO:0051168 69 48 1,000 6,578E-04 0,01528177 ! regulation of intracellular transport GO:0032386 78 49 1,000 6,855E-04 0,01576552 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 6,855E-04 0,01560943 ! positive regulation of growth GO:0045927 67 50 1,000 7,137E-04 0,01609305 ! nucleotide-excision repair GO:0006289 64 52 1,000 7,718E-04 0,017235 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 8,948E-04 0,01978781 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 9,269E-04 0,02030277 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 9,269E-04 0,02011124 ! developmental maturation GO:0021700 75 57 1,000 9,269E-04 0,01992328 ! negative regulation of kinase activity GO:0033673 100 58 1,000 9,595E-04 0,02043441 ! lung development GO:0030324 94 59 1,000 9,927E-04 0,02094778 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 1,027E-03 0,02146329 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of transferase activity GO:0051348 105 61 1,000 1,061E-03 0,02198089 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 1,061E-03 0,02178463 ! respiratory tube development GO:0030323 99 62 1,000 1,096E-03 0,02230137 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 1,096E-03 0,02210575 ! appendage morphogenesis GO:0035107 93 64 1,000 1,167E-03 0,0233407 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 1,167E-03 0,02313949 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 1,167E-03 0,02294172 ! respiratory system development GO:0060541 100 64 1,000 1,167E-03 0,0227473 ! regulation of caspase activity GO:0043281 97 65 1,000 1,204E-03 0,02326157 ! appendage development GO:0048736 94 65 1,000 1,204E-03 0,02306772 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 1,204E-03 0,02287708 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 1,204E-03 0,02268956 ! regulation of actin filament-based process GO:0032970 99 66 1,000 1,241E-03 0,02319777 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 1,241E-03 0,02301069 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 1,278E-03 0,0235182 ! regulation of neuron differentiation GO:0045664 107 67 1,000 1,278E-03 0,02333155 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 1,316E-03 0,02383838 ! positive regulation of ligase activity GO:0051351 99 69 1,000 1,355E-03 0,02434704 ! response to metal ion GO:0010038 103 70 1,000 1,394E-03 0,02485747 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 1,394E-03 0,02466626 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 1,434E-03 0,02517596 ! regulation of peptidase activity GO:0052547 106 72 1,000 1,474E-03 0,02568735 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 1,474E-03 0,02549421 GO:0045937|positive regulation of phosphate metabolic process, ! tube morphogenesis GO:0035239 118 73 1,000 1,515E-03 0,02600485 ! mitochondrion organization GO:0007005 104 73 1,000 1,515E-03 0,02581222 ! response to inorganic substance GO:0010035 115 75 1,000 1,598E-03 0,02703091 ! regulation of ligase activity GO:0051340 114 75 1,000 1,598E-03 0,0268336 ! response to unfolded protein GO:0006986 99 76 1,000 1,641E-03 0,02734663 ! regulation of protein transport GO:0051223 114 76 1,000 1,641E-03 0,02714989 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 107 78 1,000 1,727E-03 0,02837711 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 1,816E-03 0,02962181 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 1,000 1,816E-03 0,02941321 ! forebrain development GO:0030900 131 80 1,000 1,816E-03 0,02920752 ! response to protein stimulus GO:0051789 111 81 1,000 1,861E-03 0,02972539 ! regulation of cell adhesion GO:0030155 159 83 1,000 1,953E-03 0,03097718 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 2,047E-03 0,03224528 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 2,047E-03 0,03202592 ! regulation of protein localization GO:0032880 132 85 1,000 2,047E-03 0,03180953 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 2,047E-03 0,03159604 ! cell cycle arrest GO:0007050 150 86 1,000 2,095E-03 0,03211799 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 2,143E-03 0,03264107 ! establishment of RNA localization GO:0051236 128 88 1,000 2,192E-03 0,03316526 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of neurogenesis GO:0050767 153 89 1,000 2,241E-03 0,03369053 ! RNA localization GO:0006403 135 91 1,000 2,341E-03 0,03496976 ! cell fate commitment GO:0045165 141 92 1,000 2,392E-03 0,03550001 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 2,444E-03 0,03603119 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 2,444E-03 0,03580169 ! polysaccharide metabolic process GO:0005976 129 93 1,000 2,444E-03 0,03557509 ! angiogenesis GO:0001525 149 95 1,000 2,548E-03 0,03686291 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 2,601E-03 0,03739484 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 2,601E-03 0,03716257 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 2,764E-03 0,03923625 ! regulation of translation GO:0006417 151 100 1,000 2,819E-03 0,03977318 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 3,998E-03 0,05607186 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 3,998E-03 0,05573203 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 3,998E-03 0,05539629 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 3,998E-03 0,05506458 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,998E-03 0,05473681 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 3,998E-03 0,05441293 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 3,998E-03 0,05409285 ! sleep GO:0030431 11 5 0,000 3,998E-03 0,05377652 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,998E-03 0,05346386 ! nucleotide-sugar transport GO:0015780 8 5 0,000 3,998E-03 0,05315482 ! regulation of interferon-beta production GO:0032648 5 5 0,000 3,998E-03 0,05284934 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 3,998E-03 0,05254734 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 3,998E-03 0,05224878 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 3,998E-03 0,05195358 ! tongue development GO:0043586 6 5 0,000 3,998E-03 0,05166171 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 3,998E-03 0,0513731 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,998E-03 0,05108769 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 3,998E-03 0,05080544 ! cobalt ion transport GO:0006824 9 5 0,000 3,998E-03 0,05052629 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 3,998E-03 0,05025019 ! SMAD protein complex assembly GO:0007183 9 5 0,000 3,998E-03 0,04997709 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 3,998E-03 0,04970694 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 3,998E-03 0,0494397 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 3,998E-03 0,04917532 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 3,998E-03 0,04891375 ! embryonic camera-type eye development GO:0031076 8 5 0,000 3,998E-03 0,04865494 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 3,998E-03 0,04839887 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 3,998E-03 0,04814547 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,998E-03 0,04789471 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,998E-03 0,04764655 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,998E-03 0,04740095 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 3,998E-03 0,04715787 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 3,998E-03 0,04691727 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,998E-03 0,04667911 ! malate metabolic process GO:0006108 7 5 0,000 3,998E-03 0,04644336 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 3,998E-03 0,04620997 ! behavioral response to pain GO:0048266 7 5 0,000 3,998E-03 0,04597892 ! clathrin coat assembly GO:0048268 11 5 0,000 3,998E-03 0,04575017 ! phototransduction, visible light GO:0007603 6 5 0,000 3,998E-03 0,04552369 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,998E-03 0,04529943 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 3,998E-03 0,04507737 ! mating behavior GO:0007617 6 5 0,000 3,998E-03 0,04485749 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,998E-03 0,04463973 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 3,998E-03 0,04442408 ! rhythmic behavior GO:0007622 12 5 0,000 3,998E-03 0,0442105 ! copulation GO:0007620 7 5 0,000 3,998E-03 0,04399897 ! glial cell fate commitment GO:0021781 12 5 0,000 3,998E-03 0,04378945 ! protein maturation by protein folding GO:0022417 12 5 0,000 3,998E-03 0,04358192 ! embryonic hemopoiesis GO:0035162 10 5 0,000 3,998E-03 0,04337634 ! regulation of potassium ion transport GO:0043266 9 5 0,000 3,998E-03 0,0431727 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 3,998E-03 0,04297096 ! apoptotic cell clearance GO:0043277 13 5 0,000 3,998E-03 0,04277109 ! lipoprotein particle clearance GO:0034381 9 5 0,000 3,998E-03 0,04257308 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 3,998E-03 0,04237689 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,998E-03 0,0421825 ! response to protozoan GO:0001562 9 5 0,000 3,998E-03 0,04198988 ! positive regulation of glycolysis GO:0045821 11 5 0,000 3,998E-03 0,04179902 ! lymph vessel development GO:0001945 7 5 0,000 3,998E-03 0,04160988 ! endochondral ossification GO:0001958 12 5 0,000 3,998E-03 0,04142245 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 3,998E-03 0,0412367 ! parathyroid gland development GO:0060017 8 5 0,000 3,998E-03 0,04105261 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 3,998E-03 0,04087015 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 3,998E-03 0,04068931 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 3,998E-03 0,04051006 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 3,998E-03 0,04033239 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 3,998E-03 0,04015626 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 3,998E-03 0,03998167 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 3,998E-03 0,03980859 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 3,998E-03 0,039637 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 3,998E-03 0,03946689 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 3,998E-03 0,03929822 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 3,998E-03 0,039131 ! cardiac muscle fiber development GO:0048739 7 5 0,000 3,998E-03 0,03896519 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 3,998E-03 0,03880078 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 3,998E-03 0,03863775 ! neutrophil mediated immunity GO:0002446 6 5 0,000 3,998E-03 0,03847609 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 3,998E-03 0,03831577 ! ovulation GO:0030728 6 5 0,000 3,998E-03 0,03815678 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 3,998E-03 0,03799911 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 3,998E-03 0,03784273 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 3,998E-03 0,03768764 ! response to pH GO:0009268 9 5 0,000 3,998E-03 0,03753381 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 3,998E-03 0,03738124 ! proline biosynthetic process GO:0006561 6 5 0,000 3,998E-03 0,0372299 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,998E-03 0,03707978 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 3,998E-03 0,03693086 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,998E-03 0,03678314 ! polyol catabolic process GO:0046174 7 5 0,000 3,998E-03 0,03663659 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 3,998E-03 0,03649121 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,998E-03 0,03634697 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,998E-03 0,03620388 ! sister chromatid cohesion GO:0007062 9 5 0,000 3,998E-03 0,0360619 ! nerve growth factor processing GO:0032455 7 5 0,000 3,998E-03 0,03592103 ! urea metabolic process GO:0019627 6 5 0,000 3,998E-03 0,03578126 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 3,998E-03 0,03564258 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,998E-03 0,03550496 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 3,998E-03 0,0353684 ! neutrophil activation GO:0042119 5 5 0,000 3,998E-03 0,03523289 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 3,998E-03 0,03509841 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 3,998E-03 0,03496496 ! response to food GO:0032094 5 5 0,000 3,998E-03 0,03483252 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 3,998E-03 0,03470107 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,998E-03 0,03457062 ! paraxial mesoderm development GO:0048339 9 5 0,000 3,998E-03 0,03444114 ! forebrain neuron development GO:0021884 7 5 0,000 3,998E-03 0,03431263 ! melanosome organization GO:0032438 7 5 0,000 3,998E-03 0,03418507 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 3,998E-03 0,03405846 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 3,998E-03 0,03393278 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 3,998E-03 0,03380803 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,998E-03 0,03368419 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 3,998E-03 0,03356126 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 3,998E-03 0,03343922 ! nucleoside transport GO:0015858 6 5 0,000 3,998E-03 0,03331806 ! nucleoside salvage GO:0043174 7 5 0,000 3,998E-03 0,03319778 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 3,998E-03 0,03307836 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,998E-03 0,0329598 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 3,998E-03 0,03284209 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 3,998E-03 0,03272521 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,998E-03 0,03260916 ! early endosome to late endosome transport GO:0045022 11 5 0,000 3,998E-03 0,03249394 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,998E-03 0,03237952 ! depyrimidination GO:0045008 8 5 0,000 3,998E-03 0,03226591 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 3,998E-03 0,03215309 ! 5S class rRNA transcription GO:0042791 8 5 0,000 3,998E-03 0,03204106 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 3,998E-03 0,03192981 ! regulation of centrosome cycle GO:0046605 7 5 0,000 3,998E-03 0,03181932 ! neuronal ion channel clustering GO:0045161 7 5 0,000 3,998E-03 0,0317096 ! sodium ion homeostasis GO:0055078 6 5 0,000 3,998E-03 0,03160063 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 3,998E-03 0,03149241 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 3,998E-03 0,03138493 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 3,998E-03 0,03127818 ! monocyte differentiation GO:0030224 8 5 0,000 3,998E-03 0,03117215 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 3,998E-03 0,03106684 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 3,998E-03 0,03096224 ! centrosome duplication GO:0051298 5 5 0,000 3,998E-03 0,03085834 ! response to UV-C GO:0010225 6 5 0,000 3,998E-03 0,03075513 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 3,998E-03 0,03065261 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 3,998E-03 0,03055078 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 3,998E-03 0,03044962 ! regulation of dendrite development GO:0050773 12 5 0,000 3,998E-03 0,03034912 ! peptidyl-arginine modification GO:0018195 7 5 0,000 3,998E-03 0,03024929 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,998E-03 0,03015011 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 3,998E-03 0,03005158 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 3,998E-03 0,0299537 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 3,998E-03 0,02985644 ! regulation of dopamine secretion GO:0014059 12 5 0,000 3,998E-03 0,02975982 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 3,998E-03 0,02966382 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 3,998E-03 0,02956844 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 3,998E-03 0,02947367 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,998E-03 0,0293795 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 3,998E-03 0,02928594 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,998E-03 0,02919297 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 3,998E-03 0,02910058 ! neural tube patterning GO:0021532 6 5 0,000 3,998E-03 0,02900878 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 3,998E-03 0,02891756 ! histone demethylation GO:0016577 9 5 0,000 3,998E-03 0,02882691 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 3,998E-03 0,02873683 ! regulation of sterol transport GO:0032371 7 5 0,000 3,998E-03 0,0286473 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 3,998E-03 0,02855834 ! enteric nervous system development GO:0048484 8 5 0,000 3,998E-03 0,02846992 ! establishment of planar polarity GO:0001736 6 5 0,000 3,998E-03 0,02838205 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 3,998E-03 0,02829472 ! muscle cell proliferation GO:0033002 8 5 0,000 3,998E-03 0,02820793 ! transcription termination GO:0006353 8 5 0,000 3,998E-03 0,02812167 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 3,998E-03 0,02803593 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 3,998E-03 0,02795071 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 3,998E-03 0,02786601 ! regulation of respiratory burst GO:0060263 8 5 0,000 3,998E-03 0,02778183 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 3,998E-03 0,02769815 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,998E-03 0,02761497 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,998E-03 0,02753229 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 3,998E-03 0,0274501 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 3,998E-03 0,02736841 ! apical protein localization GO:0045176 6 5 0,000 3,998E-03 0,02728719 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 3,998E-03 0,02720646 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 3,998E-03 0,02712621 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,998E-03 0,02704642 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 3,998E-03 0,02696711 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 3,998E-03 0,02688826 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 3,998E-03 0,02680987 ! triglyceride catabolic process GO:0019433 6 5 0,000 3,998E-03 0,02673193 ! glial cell migration GO:0008347 10 5 0,000 3,998E-03 0,02665445 ! determination of adult lifespan GO:0008340 8 5 0,000 3,998E-03 0,02657741 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 3,998E-03 0,02650082 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,998E-03 0,02642467 ! somatic stem cell maintenance GO:0035019 13 5 0,000 3,998E-03 0,02634895 ! cerebellar cortex formation GO:0021697 6 5 0,000 3,998E-03 0,02627367 ! neural plate development GO:0001840 6 5 0,000 3,998E-03 0,02619882 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 3,998E-03 0,02612439 ! regulation of sensory perception GO:0051931 6 5 0,000 3,998E-03 0,02605038 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 3,998E-03 0,02597679 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 3,998E-03 0,02590362 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 3,998E-03 0,02583086 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 3,998E-03 0,0257585 ! sensory cilium assembly GO:0035058 6 5 0,000 3,998E-03 0,02568655 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 3,998E-03 0,025615 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,998E-03 0,02554385 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 3,998E-03 0,02547309 ! spindle assembly GO:0051225 5 5 0,000 3,998E-03 0,02540272 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 3,998E-03 0,02533274 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 3,998E-03 0,02526314 ! protein amino acid prenylation GO:0018346 9 5 0,000 3,998E-03 0,02519393 ! organ regeneration GO:0031100 7 5 0,000 3,998E-03 0,02512509 ! NAD biosynthetic process GO:0009435 7 5 0,000 3,998E-03 0,02505663 ! carnitine metabolic process GO:0009437 5 5 0,000 3,998E-03 0,02498854 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 3,998E-03 0,02492083 ! cellular anion homeostasis GO:0030002 6 5 0,000 3,998E-03 0,02485347 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 11 6 0,000 4,796E-03 0,02973272 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 4,796E-03 0,02965279 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 4,796E-03 0,0295733 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 4,796E-03 0,02949422 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 4,796E-03 0,02941557 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 4,796E-03 0,02933734 ! regulation of helicase activity GO:0051095 11 6 0,000 4,796E-03 0,02925952 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 4,796E-03 0,02918212 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 4,796E-03 0,02910512 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 4,796E-03 0,02902853 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 4,796E-03 0,02895234 ! positive regulation of axon extension GO:0045773 8 6 0,000 4,796E-03 0,02887654 ! prostate gland development GO:0030850 9 6 0,000 4,796E-03 0,02880115 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 4,796E-03 0,02872614 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 4,796E-03 0,02865153 ! forebrain neuron differentiation GO:0021879 9 6 0,000 4,796E-03 0,0285773 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 4,796E-03 0,02850346 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 4,796E-03 0,02843 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 4,796E-03 0,02835691 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 4,796E-03 0,0282842 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 4,796E-03 0,02821187 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 4,796E-03 0,0281399 ! neuron adhesion GO:0007158 9 6 0,000 4,796E-03 0,02806829 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 4,796E-03 0,02799705 ! establishment of tissue polarity GO:0007164 7 6 0,000 4,796E-03 0,02792618 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 4,796E-03 0,02785566 ! signal peptide processing GO:0006465 8 6 0,000 4,796E-03 0,02778549 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 4,796E-03 0,02771568 ! mRNA stabilization GO:0048255 15 6 0,000 4,796E-03 0,02764621 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 4,796E-03 0,0275771 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 4,796E-03 0,02750833 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 4,796E-03 0,0274399 ! opsonization GO:0008228 8 6 0,000 4,796E-03 0,02737181 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 4,796E-03 0,02730406 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 4,796E-03 0,02723664 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 4,796E-03 0,02716956 ! protein amino acid dealkylation GO:0008214 11 6 0,000 4,796E-03 0,0271028 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 4,796E-03 0,02703637 ! photoreceptor cell development GO:0042461 10 6 0,000 4,796E-03 0,02697027 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 4,796E-03 0,02690449 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 4,796E-03 0,02683903 ! mechanosensory behavior GO:0007638 8 6 0,000 4,796E-03 0,02677388 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 4,796E-03 0,02670905 ! negative regulation of endocytosis GO:0045806 8 6 0,000 4,796E-03 0,02664454 ! response to interferon-gamma GO:0034341 12 6 0,000 4,796E-03 0,02658034 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 4,796E-03 0,02651644 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 4,796E-03 0,02645285 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 4,796E-03 0,02638957 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 4,796E-03 0,02632659 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 4,796E-03 0,0262639 ! cGMP-mediated signaling GO:0019934 10 6 0,000 4,796E-03 0,02620152 ! activation of MAPKKK activity GO:0000185 10 6 0,000 4,796E-03 0,02613943 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 4,796E-03 0,02607764 ! thymic T cell selection GO:0045061 12 6 0,000 4,796E-03 0,02601613 ! protein lipoylation GO:0009249 10 6 0,000 4,796E-03 0,02595492 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 4,796E-03 0,02589399 ! pigment granule organization GO:0048753 11 6 0,000 4,796E-03 0,02583335 ! drug transport GO:0015893 6 6 0,000 4,796E-03 0,02577299 ! cysteine metabolic process GO:0006534 7 6 0,000 4,796E-03 0,02571291 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 4,796E-03 0,02565312 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 4,796E-03 0,0255936 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 4,796E-03 0,02553435 ! histidine metabolic process GO:0006547 6 6 0,000 4,796E-03 0,02547538 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 4,796E-03 0,02541668 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 4,796E-03 0,02535825 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 4,796E-03 0,02530009 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 4,796E-03 0,0252422 ! adenohypophysis development GO:0021984 10 6 0,000 4,796E-03 0,02518457 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 4,796E-03 0,0251272 ! hyperosmotic response GO:0006972 8 6 0,000 4,796E-03 0,02507009 ! microtubule nucleation GO:0007020 10 6 0,000 4,796E-03 0,02501324 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 4,796E-03 0,02495665 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 4,796E-03 0,02490032 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 4,796E-03 0,02484423 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 4,796E-03 0,0247884 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 4,796E-03 0,02473282 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 4,796E-03 0,02467749 ! response to dietary excess GO:0002021 7 6 0,000 4,796E-03 0,02462241 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 4,796E-03 0,02456757 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 4,796E-03 0,02451298 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 4,796E-03 0,02445862 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 4,796E-03 0,02440451 ! glycerol ether catabolic process GO:0044269 8 6 0,000 4,796E-03 0,02435064 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 4,796E-03 0,024297 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 4,796E-03 0,0242436 ! neuron apoptosis GO:0051402 8 6 0,000 4,796E-03 0,02419044 ! organic alcohol transport GO:0015850 9 6 0,000 4,796E-03 0,0241375 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 4,796E-03 0,0240848 ! T cell mediated immunity GO:0002456 12 6 0,000 4,796E-03 0,02403233 ! male sex determination GO:0030238 9 6 0,000 4,796E-03 0,02398009 ! carnitine transport GO:0015879 8 6 0,000 4,796E-03 0,02392807 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 4,796E-03 0,02387628 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 4,796E-03 0,02382471 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,796E-03 0,02377336 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 4,796E-03 0,02372224 ! positive regulation of exocytosis GO:0045921 6 6 0,000 4,796E-03 0,02367133 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 4,796E-03 0,02362064 ! parturition GO:0007567 12 6 0,000 4,796E-03 0,02357017 ! negative regulation of translational initiation GO:0045947 7 6 0,000 4,796E-03 0,02351991 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 4,796E-03 0,02346987 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 4,796E-03 0,02342004 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 4,796E-03 0,02337042 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 4,796E-03 0,02332101 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 4,796E-03 0,02327181 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 4,796E-03 0,02322282 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 4,796E-03 0,02317403 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 4,796E-03 0,02312545 ! macrophage differentiation GO:0030225 10 6 0,000 4,796E-03 0,02307707 ! astrocyte development GO:0014002 14 6 0,000 4,796E-03 0,02302889 ! hyaluronan metabolic process GO:0030212 6 6 0,000 4,796E-03 0,02298092 ! purine base biosynthetic process GO:0009113 14 6 0,000 4,796E-03 0,02293314 ! interaction with symbiont GO:0051702 8 6 0,000 4,796E-03 0,02288556 ! anterograde axon cargo transport GO:0008089 8 6 0,000 4,796E-03 0,02283818 ! skeletal muscle contraction GO:0003009 6 6 0,000 4,796E-03 0,02279099 ! eating behavior GO:0042755 6 6 0,000 4,796E-03 0,022744 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 4,796E-03 0,0226972 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 4,796E-03 0,02265059 ! response to copper ion GO:0046688 9 6 0,000 4,796E-03 0,02260418 ! DNA topological change GO:0006265 8 6 0,000 4,796E-03 0,02255795 ! response to exogenous dsRNA GO:0043330 8 6 0,000 4,796E-03 0,02251192 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 4,796E-03 0,02246607 ! establishment of melanosome localization GO:0032401 9 6 0,000 4,796E-03 0,02242041 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,796E-03 0,02237493 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 4,796E-03 0,02232963 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 4,796E-03 0,02228452 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 4,796E-03 0,0222396 ! nucleoside catabolic process GO:0009164 6 6 0,000 4,796E-03 0,02219485 ! gas homeostasis GO:0033483 11 6 0,000 4,796E-03 0,02215028 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 4,796E-03 0,02210589 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 4,796E-03 0,02206168 ! Schwann cell development GO:0014044 14 6 0,000 4,796E-03 0,02201764 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 4,796E-03 0,02197378 ! dendrite morphogenesis GO:0048813 9 6 0,000 4,796E-03 0,0219301 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 4,796E-03 0,02188659 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 4,796E-03 0,02184325 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 4,796E-03 0,02180008 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 4,796E-03 0,02175708 ! histone ubiquitination GO:0016574 7 6 0,000 4,796E-03 0,02171425 ! regulation of meiosis GO:0040020 10 6 0,000 4,796E-03 0,02167159 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 4,796E-03 0,0216291 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 4,796E-03 0,02158677 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 4,796E-03 0,02154461 ! regulation of mast cell activation GO:0033003 6 6 0,000 4,796E-03 0,02150261 ! membrane to membrane docking GO:0022614 12 6 0,000 4,796E-03 0,02146078 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 4,796E-03 0,02141911 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 4,796E-03 0,0213776 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 4,796E-03 0,02133625 ! receptor internalization GO:0031623 9 6 0,000 4,796E-03 0,02129506 ! neutrophil homeostasis GO:0001780 6 6 0,000 4,796E-03 0,02125403 ! coenzyme A metabolic process GO:0015936 9 6 0,000 4,796E-03 0,02121315 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,796E-03 0,02117244 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 4,796E-03 0,02113188 ! protein deubiquitination GO:0016579 8 6 0,000 4,796E-03 0,02109147 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 4,796E-03 0,02105122 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 4,796E-03 0,02101112 ! peptidyl-histidine modification GO:0018202 9 6 0,000 4,796E-03 0,02097118 ! axonal fasciculation GO:0007413 9 6 0,000 4,796E-03 0,02093138 ! thiamin metabolic process GO:0006772 6 6 0,000 4,796E-03 0,02089174 ! midbrain development GO:0030901 6 6 0,000 4,796E-03 0,02085225 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 4,796E-03 0,0208129 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 4,796E-03 0,02077371 ! progesterone metabolic process GO:0042448 8 6 0,000 4,796E-03 0,02073466 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 4,796E-03 0,02069576 ! glycolipid catabolic process GO:0019377 13 6 0,000 4,796E-03 0,020657 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 4,796E-03 0,02061839 ! positive regulation of glucose import GO:0046326 6 6 0,000 4,796E-03 0,02057992 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 4,796E-03 0,0205416 ! adult feeding behavior GO:0008343 6 6 0,000 4,796E-03 0,02050342 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 4,796E-03 0,02046538 ! blastocyst growth GO:0001832 15 6 0,000 4,796E-03 0,02042748 ! pigment granule transport GO:0051904 12 6 0,000 4,796E-03 0,02038972 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 4,796E-03 0,0203521 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 4,796E-03 0,02031462 ! catecholamine transport GO:0051937 7 6 0,000 4,796E-03 0,02027728 ! organ or tissue specific immune response GO:0002251 7 6 0,000 4,796E-03 0,02024007 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 4,796E-03 0,020203 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 4,796E-03 0,02016607 ! negative regulation of B cell activation GO:0050869 9 6 0,000 4,796E-03 0,02012927 ! protein prenylation GO:0018342 10 6 0,000 4,796E-03 0,0200926 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 4,796E-03 0,02005607 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 4,796E-03 0,02001967 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 4,796E-03 0,01998341 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 4,796E-03 0,01994727 ! positive regulation of coagulation GO:0050820 11 6 0,000 4,796E-03 0,01991126 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 5,593E-03 0,02317933 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 5,593E-03 0,02313764 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 5,593E-03 0,0230961 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 5,593E-03 0,02305471 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 5,593E-03 0,02301347 ! synaptonemal complex assembly GO:0007130 10 7 0,000 5,593E-03 0,02297237 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 5,593E-03 0,02293143 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 5,593E-03 0,02289062 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 5,593E-03 0,02284996 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 5,593E-03 0,02280945 ! reproductive behavior GO:0019098 12 7 0,000 5,593E-03 0,02276908 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 5,593E-03 0,02272885 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 5,593E-03 0,02268876 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 5,593E-03 0,02264882 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 5,593E-03 0,02260902 ! oligopeptide transport GO:0006857 11 7 0,000 5,593E-03 0,02256935 ! protein amino acid sulfation GO:0006477 9 7 0,000 5,593E-03 0,02252982 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 5,593E-03 0,02249044 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 5,593E-03 0,02245119 ! RNA methylation GO:0001510 11 7 0,000 5,593E-03 0,02241207 ! pericardium development GO:0060039 8 7 0,000 5,593E-03 0,0223731 ! macrophage chemotaxis GO:0048246 10 7 0,000 5,593E-03 0,02233425 ! fibril organization GO:0043206 13 7 0,000 5,593E-03 0,02229555 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 5,593E-03 0,02225697 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 5,593E-03 0,02221853 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 5,593E-03 0,02218022 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 5,593E-03 0,02214205 ! lipoprotein transport GO:0042953 9 7 0,000 5,593E-03 0,022104 ! cerebral cortex cell migration GO:0021795 11 7 0,000 5,593E-03 0,02206609 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 5,593E-03 0,0220283 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 5,593E-03 0,02199065 ! estrogen metabolic process GO:0008210 14 7 0,000 5,593E-03 0,02195312 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 5,593E-03 0,02191572 ! chemosensory behavior GO:0007635 9 7 0,000 5,593E-03 0,02187845 ! microtubule bundle formation GO:0001578 8 7 0,000 5,593E-03 0,02184131 ! T-helper 1 type immune response GO:0042088 11 7 0,000 5,593E-03 0,02180429 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 5,593E-03 0,02176739 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 5,593E-03 0,02173062 ! leukocyte degranulation GO:0043299 10 7 0,000 5,593E-03 0,02169398 ! bile acid and bile salt transport GO:0015721 9 7 0,000 5,593E-03 0,02165746 ! reflex GO:0060004 12 7 0,000 5,593E-03 0,02162106 ! positive regulation of isotype switching GO:0045830 15 7 0,000 5,593E-03 0,02158478 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 5,593E-03 0,02154863 ! protein-cofactor linkage GO:0018065 13 7 0,000 5,593E-03 0,02151259 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 5,593E-03 0,02147668 ! glycerolipid catabolic process GO:0046503 9 7 0,000 5,593E-03 0,02144088 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 5,593E-03 0,02140521 ! spinal cord patterning GO:0021511 7 7 0,000 5,593E-03 0,02136965 ! hemoglobin metabolic process GO:0020027 10 7 0,000 5,593E-03 0,02133421 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 5,593E-03 0,02129889 ! adrenal gland development GO:0030325 17 7 0,000 5,593E-03 0,02126369 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 5,593E-03 0,0212286 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 5,593E-03 0,02119362 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 5,593E-03 0,02115877 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 5,593E-03 0,02112402 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 5,593E-03 0,02108939 ! endosome organization GO:0007032 10 7 0,000 5,593E-03 0,02105488 ! thyroid hormone generation GO:0006590 11 7 0,000 5,593E-03 0,02102047 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 5,593E-03 0,02098618 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 5,593E-03 0,020952 ! regulation of pigmentation during development GO:0048070 15 7 0,000 5,593E-03 0,02091793 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 5,593E-03 0,02088398 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 5,593E-03 0,02085013 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 5,593E-03 0,02081639 ! galactose metabolic process GO:0006012 10 7 0,000 5,593E-03 0,02078276 ! vesicle fusion GO:0006906 15 7 0,000 5,593E-03 0,02074924 ! intracellular pH reduction GO:0051452 10 7 0,000 5,593E-03 0,02071583 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 5,593E-03 0,02068252 ! organ growth GO:0035265 11 7 0,000 5,593E-03 0,02064933 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 5,593E-03 0,02061623 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 5,593E-03 0,02058325 ! Rac protein signal transduction GO:0016601 7 7 0,000 5,593E-03 0,02055037 ! retinol metabolic process GO:0042572 9 7 0,000 5,593E-03 0,02051759 ! behavioral fear response GO:0001662 13 7 0,000 5,593E-03 0,02048492 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 5,593E-03 0,02045235 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 5,593E-03 0,02041989 ! rRNA modification GO:0000154 12 7 0,000 5,593E-03 0,02038753 ! protein heterooligomerization GO:0051291 10 7 0,000 5,593E-03 0,02035527 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 5,593E-03 0,02032311 ! response to UV-B GO:0010224 11 7 0,000 5,593E-03 0,02029106 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 5,593E-03 0,0202591 ! protein retention in ER lumen GO:0006621 12 7 0,000 5,593E-03 0,02022725 ! intermediate filament organization GO:0045109 11 7 0,000 5,593E-03 0,02019549 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 5,593E-03 0,02016384 ! cardiac muscle cell development GO:0055013 9 7 0,000 5,593E-03 0,02013228 ! fibrinolysis GO:0042730 9 7 0,000 5,593E-03 0,02010083 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 5,593E-03 0,02006947 ! regulation of circadian rhythm GO:0042752 11 7 0,000 5,593E-03 0,02003821 ! B cell lineage commitment GO:0002326 17 7 0,000 5,593E-03 0,02000704 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 5,593E-03 0,01997598 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 5,593E-03 0,01994501 ! response to tropane GO:0014073 13 7 0,000 5,593E-03 0,01991413 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 5,593E-03 0,01988335 ! melanosome localization GO:0032400 10 7 0,000 5,593E-03 0,01985267 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 5,593E-03 0,01982208 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 5,593E-03 0,01979158 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 5,593E-03 0,01976118 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 5,593E-03 0,01973087 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 5,593E-03 0,01970066 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 5,593E-03 0,01967053 ! mast cell activation GO:0045576 9 7 0,000 5,593E-03 0,0196405 ! multicellular organismal aging GO:0010259 11 7 0,000 5,593E-03 0,01961056 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 5,593E-03 0,01958071 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 5,593E-03 0,01955096 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 5,593E-03 0,01952129 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 5,593E-03 0,01949171 ! establishment of nucleus localization GO:0040023 13 7 0,000 5,593E-03 0,01946222 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 5,593E-03 0,01943282 ! T cell lineage commitment GO:0002360 12 7 0,000 5,593E-03 0,01940351 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 5,593E-03 0,01937429 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 5,593E-03 0,01934516 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 5,593E-03 0,01931611 ! regulation of lipid transport GO:0032368 13 7 0,000 5,593E-03 0,01928715 ! response to tumor cell GO:0002347 12 7 0,000 5,593E-03 0,01925828 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 5,593E-03 0,01922949 ! neuroblast proliferation GO:0007405 13 7 0,000 5,593E-03 0,01920079 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 5,593E-03 0,01917218 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 5,593E-03 0,01914365 ! peptidyl-threonine modification GO:0018210 18 7 0,000 5,593E-03 0,0191152 ! diuresis GO:0030146 12 7 0,000 5,593E-03 0,01908684 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 5,593E-03 0,01905856 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 5,593E-03 0,01903037 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 5,593E-03 0,01900226 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 5,593E-03 0,01897423 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 5,593E-03 0,01894629 ! melanin biosynthetic process GO:0042438 8 7 0,000 5,593E-03 0,01891843 ! regulation of synaptogenesis GO:0051963 10 7 0,000 5,593E-03 0,01889065 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 5,593E-03 0,01886295 ! dopamine biosynthetic process GO:0042416 15 7 0,000 5,593E-03 0,01883533 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 5,593E-03 0,01880779 ! lymph node development GO:0048535 9 7 0,000 5,593E-03 0,01878034 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 5,593E-03 0,01875296 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 5,593E-03 0,01872566 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 5,593E-03 0,01869844 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 5,593E-03 0,01867131 ! endosome to lysosome transport GO:0008333 10 7 0,000 5,593E-03 0,01864425 ! ATP catabolic process GO:0006200 10 7 0,000 5,593E-03 0,01861726 ! establishment of pigment granule localization GO:0051905 13 7 0,000 5,593E-03 0,01859036 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 5,593E-03 0,01856353 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 5,593E-03 0,01853679 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 5,593E-03 0,01851011 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 5,593E-03 0,01848352 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 5,593E-03 0,018457 ! muscle adaptation GO:0043500 12 7 0,000 5,593E-03 0,01843056 ! amino sugar catabolic process GO:0046348 9 7 0,000 5,593E-03 0,01840419 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 5,593E-03 0,0183779 ! retina homeostasis GO:0001895 9 7 0,000 5,593E-03 0,01835168 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 5,593E-03 0,01832554 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 5,593E-03 0,01829947 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 5,593E-03 0,01827348 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 5,593E-03 0,01824756 ! behavioral response to nicotine GO:0035095 11 7 0,000 5,593E-03 0,01822171 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 5,593E-03 0,01819594 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 5,593E-03 0,01817024 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 6,39E-03 0,02072899 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 6,39E-03 0,0206998 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 6,39E-03 0,02067068 ! axon extension GO:0048675 11 8 0,000 6,39E-03 0,02064165 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 6,39E-03 0,0206127 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 6,39E-03 0,02058383 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 6,39E-03 0,02055504 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 6,39E-03 0,02052633 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 6,39E-03 0,02049771 ! cell proliferation in forebrain GO:0021846 10 8 0,000 6,39E-03 0,02046916 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 6,39E-03 0,02044069 ! phosphate transport GO:0006817 10 8 0,000 6,39E-03 0,0204123 ! N-glycan processing GO:0006491 12 8 0,000 6,39E-03 0,02038399 ! Golgi to endosome transport GO:0006895 16 8 0,000 6,39E-03 0,02035576 ! UTP metabolic process GO:0046051 8 8 0,000 6,39E-03 0,0203276 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 6,39E-03 0,02029952 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 6,39E-03 0,02027153 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 6,39E-03 0,0202436 ! neurotransmitter uptake GO:0001504 10 8 0,000 6,39E-03 0,02021576 ! succinate metabolic process GO:0006105 14 8 0,000 6,39E-03 0,02018799 ! smoothened signaling pathway GO:0007224 8 8 0,000 6,39E-03 0,0201603 ! membrane hyperpolarization GO:0060081 10 8 0,000 6,39E-03 0,02013268 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 6,39E-03 0,02010514 ! middle ear morphogenesis GO:0042474 9 8 0,000 6,39E-03 0,02007767 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 6,39E-03 0,02005028 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 6,39E-03 0,02002296 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,39E-03 0,01999572 ! ganglioside metabolic process GO:0001573 15 8 0,000 6,39E-03 0,01996855 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 6,39E-03 0,01994146 ! pseudouridine synthesis GO:0001522 9 8 0,000 6,39E-03 0,01991444 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 6,39E-03 0,01988749 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 6,39E-03 0,01986062 ! endothelial cell differentiation GO:0045446 14 8 0,000 6,39E-03 0,01983381 ! ceramide biosynthetic process GO:0046513 9 8 0,000 6,39E-03 0,01980708 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 6,39E-03 0,01978042 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 6,39E-03 0,01975384 ! astrocyte differentiation GO:0048708 16 8 0,000 6,39E-03 0,01972732 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 6,39E-03 0,01970088 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 6,39E-03 0,01967451 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 6,39E-03 0,0196482 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 6,39E-03 0,01962197 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 6,39E-03 0,01959581 ! melanin metabolic process GO:0006582 12 8 0,000 6,39E-03 0,01956971 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 6,39E-03 0,01954369 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 6,39E-03 0,01951774 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 6,39E-03 0,01949185 ! macrophage activation GO:0042116 12 8 0,000 6,39E-03 0,01946603 ! regulation of type I interferon production GO:0032479 8 8 0,000 6,39E-03 0,01944029 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 6,39E-03 0,0194146 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 6,39E-03 0,01938899 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 6,39E-03 0,01936345 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,39E-03 0,01933797 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 6,39E-03 0,01931256 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 6,39E-03 0,01928721 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 6,39E-03 0,01926193 ! ruffle organization GO:0031529 11 8 0,000 6,39E-03 0,01923672 ! osteoblast development GO:0002076 13 8 0,000 6,39E-03 0,01921158 ! lens development in camera-type eye GO:0002088 10 8 0,000 6,39E-03 0,0191865 ! positive regulation of vasodilation GO:0045909 12 8 0,000 6,39E-03 0,01916148 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 6,39E-03 0,01913653 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 6,39E-03 0,01911165 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 6,39E-03 0,01908683 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 6,39E-03 0,01906207 ! Schwann cell differentiation GO:0014037 17 8 0,000 6,39E-03 0,01903738 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 6,39E-03 0,01901275 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 6,39E-03 0,01898819 ! regulation of gliogenesis GO:0014013 20 8 0,000 6,39E-03 0,01896368 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 6,39E-03 0,01893925 ! oligodendrocyte development GO:0014003 8 8 0,000 6,39E-03 0,01891487 ! segment specification GO:0007379 10 8 0,000 6,39E-03 0,01889056 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 6,39E-03 0,01886631 ! cellular extravasation GO:0045123 11 8 0,000 6,39E-03 0,01884212 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 6,39E-03 0,018818 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 6,39E-03 0,01879393 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 6,39E-03 0,01876993 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 6,39E-03 0,01874599 ! snRNA metabolic process GO:0016073 10 8 0,000 6,39E-03 0,01872211 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 6,39E-03 0,01869829 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 6,39E-03 0,01867453 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 6,39E-03 0,01865083 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 6,39E-03 0,01862719 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 6,39E-03 0,01860361 ! nucleosome disassembly GO:0006337 12 8 0,000 6,39E-03 0,0185801 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 6,39E-03 0,01855664 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! protein import into peroxisome matrix GO:0016558 14 8 0,000 6,39E-03 0,01853324 ! icosanoid secretion GO:0032309 12 8 0,000 6,39E-03 0,01850989 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 6,39E-03 0,01848661 ! leukocyte activation during immune response GO:0002366 13 8 0,000 6,39E-03 0,01846339 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 6,39E-03 0,01844022 ! cerebellum morphogenesis GO:0021587 9 8 0,000 6,39E-03 0,01841711 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 6,39E-03 0,01839406 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 6,39E-03 0,01837107 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 6,39E-03 0,01834813 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 6,39E-03 0,01832526 ! sterol catabolic process GO:0016127 9 8 0,000 6,39E-03 0,01830244 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 6,39E-03 0,01827967 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 6,39E-03 0,01825696 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 6,39E-03 0,01823431 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 6,39E-03 0,01821172 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 6,39E-03 0,01818918 ! prophase GO:0051324 11 8 0,000 6,39E-03 0,01816669 ! S phase GO:0051320 8 8 0,000 6,39E-03 0,01814427 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 6,39E-03 0,01812189 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 6,39E-03 0,01809958 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 6,39E-03 0,01807731 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 6,39E-03 0,01805511 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 6,39E-03 0,01803295 ! hormone catabolic process GO:0042447 13 8 0,000 6,39E-03 0,01801085 ! quaternary ammonium group transport GO:0015697 10 8 0,000 6,39E-03 0,01798881 ! myeloid cell homeostasis GO:0002262 8 8 0,000 6,39E-03 0,01796682 ! regulation of fibrinolysis GO:0051917 13 8 0,000 6,39E-03 0,01794488 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 6,39E-03 0,01792299 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 6,39E-03 0,01790116 ! regulation of telomere maintenance GO:0032204 10 8 0,000 6,39E-03 0,01787939 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 6,39E-03 0,01785766 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 6,39E-03 0,01783599 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 6,39E-03 0,01781437 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 6,39E-03 0,0177928 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 6,39E-03 0,01777129 ! lamellipodium assembly GO:0030032 9 8 0,000 6,39E-03 0,01774983 ! regulation of embryonic development GO:0045995 16 8 0,000 6,39E-03 0,01772841 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 6,39E-03 0,01770706 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 6,39E-03 0,01768575 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 6,39E-03 0,01766449 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 7,186E-03 0,01984132 ! regulation of developmental growth GO:0048638 13 9 0,000 7,186E-03 0,01981753 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 7,186E-03 0,01979379 ! telencephalon cell migration GO:0022029 16 9 0,000 7,186E-03 0,01977012 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 7,186E-03 0,0197465 ! pentose-phosphate shunt GO:0006098 12 9 0,000 7,186E-03 0,01972293 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 7,186E-03 0,01969943 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 7,186E-03 0,01967597 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 7,186E-03 0,01965258 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 7,186E-03 0,01962924 ! GTP metabolic process GO:0046039 9 9 0,000 7,186E-03 0,01960595 ! elastic fiber assembly GO:0048251 13 9 0,000 7,186E-03 0,01958272 ! social behavior GO:0035176 14 9 0,000 7,186E-03 0,01955955 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 7,186E-03 0,01953643 ! artery development GO:0060840 19 9 0,000 7,186E-03 0,01951336 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 7,186E-03 0,01949035 ! regulation of glycolysis GO:0006110 15 9 0,000 7,186E-03 0,0194674 ! response to pain GO:0048265 16 9 0,000 7,186E-03 0,01944449 ! protein complex disassembly GO:0043241 17 9 0,000 7,186E-03 0,01942164 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 7,186E-03 0,01939885 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 7,186E-03 0,01937611 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 7,186E-03 0,01935342 ! lung alveolus development GO:0048286 17 9 0,000 7,186E-03 0,01933078 ! ciliary or flagellar motility GO:0001539 10 9 0,000 7,186E-03 0,0193082 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 7,186E-03 0,01928567 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 7,186E-03 0,01926319 ! regulation of exit from mitosis GO:0007096 12 9 0,000 7,186E-03 0,01924077 ! ventral spinal cord development GO:0021517 11 9 0,000 7,186E-03 0,01921839 ! protein targeting to ER GO:0045047 19 9 0,000 7,186E-03 0,01919607 ! T cell selection GO:0045058 18 9 0,000 7,186E-03 0,0191738 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 7,186E-03 0,01915159 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 7,186E-03 0,01912942 ! arginine catabolic process GO:0006527 10 9 0,000 7,186E-03 0,0191073 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 7,186E-03 0,01908524 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 7,186E-03 0,01906323 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 7,186E-03 0,01904127 ! phosphagen metabolic process GO:0006599 12 9 0,000 7,186E-03 0,01901935 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 7,186E-03 0,01899749 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 7,186E-03 0,01897568 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 7,186E-03 0,01895392 ! mannose metabolic process GO:0006013 9 9 0,000 7,186E-03 0,01893221 ! substrate-bound cell migration GO:0006929 10 9 0,000 7,186E-03 0,01891055 ! receptor clustering GO:0043113 15 9 0,000 7,186E-03 0,01888894 ! epithelial cell development GO:0002064 10 9 0,000 7,186E-03 0,01886737 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 7,186E-03 0,01884586 ! retinoic acid metabolic process GO:0042573 11 9 0,000 7,186E-03 0,01882439 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 7,186E-03 0,01880298 ! positive regulation of translational initiation GO:0045948 10 9 0,000 7,186E-03 0,01878161 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 7,186E-03 0,01876029 ! motor axon guidance GO:0008045 14 9 0,000 7,186E-03 0,01873902 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 7,186E-03 0,0187178 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 7,186E-03 0,01869663 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 7,186E-03 0,0186755 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 7,186E-03 0,01865442 ! blastoderm segmentation GO:0007350 11 9 0,000 7,186E-03 0,01863339 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 7,186E-03 0,01861241 ! DNA ligation GO:0006266 14 9 0,000 7,186E-03 0,01859147 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 7,186E-03 0,01857058 ! response to amine stimulus GO:0014075 13 9 0,000 7,186E-03 0,01854974 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 7,186E-03 0,01852894 ! erythrocyte development GO:0048821 11 9 0,000 7,186E-03 0,0185082 ! renal water homeostasis GO:0003091 14 9 0,000 7,186E-03 0,01848749 ! postreplication repair GO:0006301 11 9 0,000 7,186E-03 0,01846684 ! mRNA cleavage GO:0006379 13 9 0,000 7,186E-03 0,01844623 ! hindbrain morphogenesis GO:0021575 12 9 0,000 7,186E-03 0,01842566 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 7,186E-03 0,01840514 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 7,186E-03 0,01838467 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 7,186E-03 0,01836424 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 7,186E-03 0,01834386 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 7,186E-03 0,01832352 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 7,186E-03 0,01830323 ! acid secretion GO:0046717 14 9 0,000 7,186E-03 0,01828299 ! musculoskeletal movement GO:0050881 11 9 0,000 7,186E-03 0,01826278 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 7,186E-03 0,01824263 ! methionine biosynthetic process GO:0009086 10 9 0,000 7,186E-03 0,01822251 ! purine base metabolic process GO:0006144 18 9 0,000 7,186E-03 0,01820244 ! oocyte differentiation GO:0009994 12 9 0,000 7,186E-03 0,01818242 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 7,186E-03 0,01816244 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 7,186E-03 0,0181425 ! spleen development GO:0048536 15 9 0,000 7,186E-03 0,01812261 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 7,186E-03 0,01810276 ! anterior/posterior axis specification GO:0009948 11 9 0,000 7,186E-03 0,01808295 ! regulation of RNA splicing GO:0043484 14 9 0,000 7,186E-03 0,01806319 ! detection of calcium ion GO:0005513 13 9 0,000 7,186E-03 0,01804347 ! blastocyst formation GO:0001825 12 9 0,000 7,186E-03 0,01802379 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 7,186E-03 0,01800416 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 7,186E-03 0,01798457 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 7,186E-03 0,01796502 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 7,186E-03 0,01794551 ! regulation of amino acid transport GO:0051955 11 9 0,000 7,186E-03 0,01792605 ! positive regulation of amine transport GO:0051954 15 9 0,000 7,186E-03 0,01790663 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 7,186E-03 0,01788725 ! prepulse inhibition GO:0060134 14 9 0,000 7,186E-03 0,01786791 ! embryonic placenta development GO:0001892 12 9 0,000 7,186E-03 0,01784862 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 7,186E-03 0,01782936 ! insulin secretion GO:0030073 17 9 0,000 7,186E-03 0,01781015 ! sequestering of metal ion GO:0051238 11 9 0,000 7,186E-03 0,01779098 ! response to nicotine GO:0035094 16 9 0,000 7,186E-03 0,01777185 ! establishment of cell polarity GO:0030010 12 9 0,000 7,186E-03 0,01775276 ! nucleus localization GO:0051647 15 9 0,000 7,186E-03 0,01773371 ! regulation of synapse organization GO:0050807 12 9 0,000 7,186E-03 0,0177147 ! localization within membrane GO:0051668 15 9 0,000 7,186E-03 0,01769574 ! negative regulation of muscle development GO:0048635 12 10 0,000 7,981E-03 0,0196336 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 7,981E-03 0,01961263 ! neuron fate specification GO:0048665 11 10 0,000 7,981E-03 0,0195917 ! negative regulation of blood pressure GO:0045776 22 10 0,000 7,981E-03 0,01957081 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 7,981E-03 0,01954997 ! thyroid gland development GO:0030878 19 10 0,000 7,981E-03 0,01952917 ! regulation of B cell proliferation GO:0030888 15 10 0,000 7,981E-03 0,01950842 ! synapsis GO:0007129 13 10 0,000 7,981E-03 0,01948771 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 7,981E-03 0,01946704 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 7,981E-03 0,01944642 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 7,981E-03 0,01942584 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 7,981E-03 0,01940531 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 7,981E-03 0,01938481 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 7,981E-03 0,01936437 ! androgen metabolic process GO:0008209 13 10 0,000 7,981E-03 0,01934396 ! phospholipid efflux GO:0033700 16 10 0,000 7,981E-03 0,0193236 ! hippocampus development GO:0021766 19 10 0,000 7,981E-03 0,01930328 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 7,981E-03 0,019283 ! blood vessel remodeling GO:0001974 21 10 0,000 7,981E-03 0,01926277 ! positive regulation of heart contraction GO:0045823 14 10 0,000 7,981E-03 0,01924258 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 7,981E-03 0,01922243 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 7,981E-03 0,01920232 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 7,981E-03 0,01918226 ! pathogenesis GO:0009405 13 10 0,000 7,981E-03 0,01916223 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 7,981E-03 0,01914225 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 7,981E-03 0,01912231 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 7,981E-03 0,01910241 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 7,981E-03 0,01908256 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 7,981E-03 0,01906274 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 7,981E-03 0,01904297 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 7,981E-03 0,01902323 ! melanocyte differentiation GO:0030318 15 10 0,000 7,981E-03 0,01900354 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 7,981E-03 0,01898389 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 7,981E-03 0,01896428 ! reverse cholesterol transport GO:0043691 16 10 0,000 7,981E-03 0,0189447 ! response to X-ray GO:0010165 16 10 0,000 7,981E-03 0,01892517 ! B cell proliferation GO:0042100 14 10 0,000 7,981E-03 0,01890568 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 7,981E-03 0,01888623 ! regulation of sodium ion transport GO:0002028 15 10 0,000 7,981E-03 0,01886682 ! forebrain cell migration GO:0021885 17 10 0,000 7,981E-03 0,01884745 ! lipid digestion GO:0044241 15 10 0,000 7,981E-03 0,01882812 ! phagocytosis, engulfment GO:0006911 20 10 0,000 7,981E-03 0,01880883 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 7,981E-03 0,01878958 ! entry into host cell GO:0030260 20 10 0,000 7,981E-03 0,01877037 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 7,981E-03 0,01875119 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 7,981E-03 0,01873206 ! negative regulation of ossification GO:0030279 19 10 0,000 7,981E-03 0,01871297 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 7,981E-03 0,01869391 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 7,981E-03 0,01867489 ! regulation of bone resorption GO:0045124 24 10 0,000 7,981E-03 0,01865591 ! alpha-beta T cell activation GO:0046631 16 10 0,000 7,981E-03 0,01863697 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 7,981E-03 0,01861807 ! regulation of organ growth GO:0046620 11 10 0,000 7,981E-03 0,01859921 ! response to dsRNA GO:0043331 18 10 0,000 7,981E-03 0,01858038 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 7,981E-03 0,0185616 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 7,981E-03 0,01854285 ! embryonic axis specification GO:0000578 12 10 0,000 7,981E-03 0,01852414 ! regulation of B cell differentiation GO:0045577 16 10 0,000 7,981E-03 0,01850546 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 7,981E-03 0,01848683 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 7,981E-03 0,01846823 ! cranial nerve development GO:0021545 12 10 0,000 7,981E-03 0,01844967 ! fucose catabolic process GO:0019317 16 10 0,000 7,981E-03 0,01843114 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 7,981E-03 0,01841266 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 7,981E-03 0,01839421 ! protein sumoylation GO:0016925 12 10 0,000 7,981E-03 0,01837579 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 7,981E-03 0,01835742 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 7,981E-03 0,01833908 ! zymogen activation GO:0031638 14 10 0,000 7,981E-03 0,01832078 ! salivary gland development GO:0007431 22 10 0,000 7,981E-03 0,01830251 ! negative regulation of neurological system process GO:0031645 19 10 0,000 7,981E-03 0,01828428 ! glutathione biosynthetic process GO:0006750 11 10 0,000 7,981E-03 0,01826609 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 7,981E-03 0,01824793 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 7,981E-03 0,01822981 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 7,981E-03 0,01821173 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 7,981E-03 0,01819368 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 7,981E-03 0,01817566 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 7,981E-03 0,01815768 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 7,981E-03 0,01813974 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 7,981E-03 0,01812184 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 7,981E-03 0,01810396 ! detection of bacterium GO:0016045 10 10 0,000 7,981E-03 0,01808613 ! embryonic gut development GO:0048566 11 10 0,000 7,981E-03 0,01806833 ! activation of innate immune response GO:0002218 10 10 0,000 7,981E-03 0,01805056 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 7,981E-03 0,01803283 ! developmental induction GO:0031128 13 10 0,000 7,981E-03 0,01801513 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 7,981E-03 0,01799747 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 7,981E-03 0,01797984 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 7,981E-03 0,01796225 ! negative regulation of immune effector process GO:0002698 16 10 0,000 7,981E-03 0,01794469 ! rRNA transcription GO:0009303 17 11 0,000 8,776E-03 0,01971256 ! respiratory burst GO:0045730 14 11 0,000 8,776E-03 0,01969333 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 8,776E-03 0,01967413 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 8,776E-03 0,01965497 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 8,776E-03 0,01963585 ! virus-host interaction GO:0019048 17 11 0,000 8,776E-03 0,01961677 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 8,776E-03 0,01959773 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 8,776E-03 0,01957872 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 8,776E-03 0,01955975 ! Golgi vesicle budding GO:0048194 17 11 0,000 8,776E-03 0,01954081 ! RNA polyadenylation GO:0043631 19 11 0,000 8,776E-03 0,01952191 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 8,776E-03 0,01950305 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 8,776E-03 0,01948423 ! mating GO:0007618 14 11 0,000 8,776E-03 0,01946544 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 8,776E-03 0,01944668 ! T cell proliferation GO:0042098 20 11 0,000 8,776E-03 0,01942797 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 8,776E-03 0,01940929 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 8,776E-03 0,01939064 ! bone resorption GO:0045453 16 11 0,000 8,776E-03 0,01937203 ! regulated secretory pathway GO:0045055 14 11 0,000 8,776E-03 0,01935346 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 8,776E-03 0,01933492 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 8,776E-03 0,01931642 ! regulation of mRNA processing GO:0050684 18 11 0,000 8,776E-03 0,01929795 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 8,776E-03 0,01927952 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 8,776E-03 0,01926112 ! syncytium formation GO:0006949 15 11 0,000 8,776E-03 0,01924276 ! plasma membrane organization GO:0007009 18 11 0,000 8,776E-03 0,01922444 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 8,776E-03 0,01920614 ! focal adhesion formation GO:0048041 24 11 0,000 8,776E-03 0,01918789 ! mitotic spindle organization GO:0007052 15 11 0,000 8,776E-03 0,01916967 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 8,776E-03 0,01915148 ! regulation of intracellular pH GO:0051453 17 11 0,000 8,776E-03 0,01913333 ! membrane protein proteolysis GO:0033619 18 11 0,000 8,776E-03 0,01911521 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 8,776E-03 0,01909712 ! adult heart development GO:0007512 11 11 0,000 8,776E-03 0,01907907 ! chondrocyte differentiation GO:0002062 17 11 0,000 8,776E-03 0,01906106 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 8,776E-03 0,01904307 ! temperature homeostasis GO:0001659 16 11 0,000 8,776E-03 0,01902513 ! L-glutamate transport GO:0015813 16 11 0,000 8,776E-03 0,01900721 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 8,776E-03 0,01898933 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 8,776E-03 0,01897148 ! protein targeting to peroxisome GO:0006625 20 11 0,000 8,776E-03 0,01895367 ! stem cell development GO:0048864 29 11 0,000 8,776E-03 0,01893589 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 8,776E-03 0,01891814 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 8,776E-03 0,01890043 ! regulation of phagocytosis GO:0050764 14 11 0,000 8,776E-03 0,01888275 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 8,776E-03 0,0188651 ! vasoconstriction GO:0042310 15 11 0,000 8,776E-03 0,01884749 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 8,776E-03 0,01882991 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 8,776E-03 0,01881236 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 8,776E-03 0,01879484 ! ribosome assembly GO:0042255 13 11 0,000 8,776E-03 0,01877736 ! nitric oxide metabolic process GO:0046209 14 11 0,000 8,776E-03 0,01875991 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 8,776E-03 0,01874249 ! chromatin silencing GO:0006342 19 11 0,000 8,776E-03 0,0187251 ! nucleosome positioning GO:0016584 13 11 0,000 8,776E-03 0,01870775 ! T cell homeostasis GO:0043029 20 11 0,000 8,776E-03 0,01869042 ! regulation of isotype switching GO:0045191 19 11 0,000 8,776E-03 0,01867313 ! regulation of leukocyte migration GO:0002685 24 11 0,000 8,776E-03 0,01865588 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 8,776E-03 0,01863865 ! protein-chromophore linkage GO:0018298 13 11 0,000 8,776E-03 0,01862146 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 8,776E-03 0,01860429 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 8,776E-03 0,01858716 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 8,776E-03 0,01857006 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 8,776E-03 0,01855299 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 8,776E-03 0,01853596 ! male genitalia development GO:0030539 13 11 0,000 8,776E-03 0,01851895 ! cholesterol efflux GO:0033344 19 11 0,000 8,776E-03 0,01850198 ! biogenic amine catabolic process GO:0042402 21 11 0,000 8,776E-03 0,01848504 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 8,776E-03 0,01846812 ! negative regulation of glucose import GO:0046325 14 11 0,000 8,776E-03 0,01845124 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 8,776E-03 0,01843439 ! regulation of organic acid transport GO:0032890 17 11 0,000 8,776E-03 0,01841757 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 8,776E-03 0,01840078 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 8,776E-03 0,01838402 ! mRNA 3'-end processing GO:0031124 19 11 0,000 8,776E-03 0,0183673 ! lysogeny GO:0030069 18 11 0,000 8,776E-03 0,0183506 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 8,776E-03 0,01833393 ! acrosome reaction GO:0007340 13 11 0,000 8,776E-03 0,01831729 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 8,776E-03 0,01830069 ! lactation GO:0007595 20 12 0,000 9,571E-03 0,01993889 ! reproductive cellular process GO:0048610 14 12 0,000 9,571E-03 0,01992085 ! tRNA modification GO:0006400 14 12 0,000 9,571E-03 0,01990284 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 9,571E-03 0,01988486 ! positive regulation of blood pressure GO:0045777 16 12 0,000 9,571E-03 0,01986691 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 9,571E-03 0,019849 ! 'de novo' protein folding GO:0006458 18 12 0,000 9,571E-03 0,01983111 ! dicarboxylic acid transport GO:0006835 22 12 0,000 9,571E-03 0,01981326 ! non-recombinational repair GO:0000726 19 12 0,000 9,571E-03 0,01979545 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 9,571E-03 0,01977766 ! peroxisomal transport GO:0043574 21 12 0,000 9,571E-03 0,01975991 ! cartilage condensation GO:0001502 18 12 0,000 9,571E-03 0,01974219 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 9,571E-03 0,0197245 ! cytokine biosynthetic process GO:0042089 16 12 0,000 9,571E-03 0,01970684 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 9,571E-03 0,01968921 ! heart looping GO:0001947 15 12 0,000 9,571E-03 0,01967162 ! palate development GO:0060021 15 12 0,000 9,571E-03 0,01965405 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 9,571E-03 0,01963652 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 9,571E-03 0,01961902 ! arginine metabolic process GO:0006525 13 12 0,000 9,571E-03 0,01960155 ! glycoprotein catabolic process GO:0006516 19 12 0,000 9,571E-03 0,01958411 ! methionine metabolic process GO:0006555 13 12 0,000 9,571E-03 0,0195667 ! tyrosine metabolic process GO:0006570 14 12 0,000 9,571E-03 0,01954932 ! Golgi organization GO:0007030 18 12 0,000 9,571E-03 0,01953198 ! cell-cell junction assembly GO:0007043 18 12 0,000 9,571E-03 0,01951466 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 9,571E-03 0,01949738 ! monoamine transport GO:0015844 13 12 0,000 9,571E-03 0,01948012 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 9,571E-03 0,0194629 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 9,571E-03 0,0194457 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 9,571E-03 0,01942854 ! L-amino acid transport GO:0015807 20 12 0,000 9,571E-03 0,01941141 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 9,571E-03 0,01939431 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 9,571E-03 0,01937723 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 9,571E-03 0,01936019 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 9,571E-03 0,01934318 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 9,571E-03 0,0193262 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 9,571E-03 0,01930924 ! cerebellum development GO:0021549 13 12 0,000 9,571E-03 0,01929232 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 9,571E-03 0,01927543 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 9,571E-03 0,01925856 ! histone acetylation GO:0016573 23 12 0,000 9,571E-03 0,01924173 ! histone methylation GO:0016571 15 12 0,000 9,571E-03 0,01922492 ! autonomic nervous system development GO:0048483 23 12 0,000 9,571E-03 0,01920815 ! gland morphogenesis GO:0022612 23 12 0,000 9,571E-03 0,0191914 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 9,571E-03 0,01917468 ! peptidyl-lysine modification GO:0018205 18 12 0,000 9,571E-03 0,019158 ! negative regulation of protein secretion GO:0050709 20 12 0,000 9,571E-03 0,01914134 ! response to gamma radiation GO:0010332 20 12 0,000 9,571E-03 0,01912471 ! intestinal absorption GO:0050892 19 12 0,000 9,571E-03 0,01910811 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 9,571E-03 0,01909153 ! cAMP biosynthetic process GO:0006171 20 12 0,000 9,571E-03 0,01907499 ! regulation of mRNA stability GO:0043488 27 12 0,000 9,571E-03 0,01905847 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 9,571E-03 0,01904199 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 9,571E-03 0,01902553 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 9,571E-03 0,0190091 ! RNA 3'-end processing GO:0031123 20 12 0,000 9,571E-03 0,0189927 ! microspike assembly GO:0030035 23 12 0,000 9,571E-03 0,01897633 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 9,571E-03 0,01895998 ! response to cold GO:0009409 14 12 0,000 9,571E-03 0,01894366 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01036437 0,02049704 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01036437 0,02047943 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01036437 0,02046185 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01036437 0,0204443 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01036437 0,02042678 ! water transport GO:0006833 17 13 0,000 0,01036437 0,0204093 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01036437 0,02039184 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01036437 0,02037441 ! lipid localization GO:0010876 24 13 0,000 0,01036437 0,02035701 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01036437 0,02033964 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01036437 0,0203223 ! organelle fusion GO:0048284 28 13 0,000 0,01036437 0,02030499 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01036437 0,02028771 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01036437 0,02027046 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01036437 0,02025323 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01036437 0,02023604 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01036437 0,02021888 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01036437 0,02020174 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01036437 0,02018464 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01036437 0,02016756 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01036437 0,02015051 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01036437 0,02013349 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01036437 0,0201165 ! NAD metabolic process GO:0019674 21 13 0,000 0,01036437 0,02009954 ! exocrine system development GO:0035272 27 13 0,000 0,01036437 0,02008261 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01036437 0,0200657 ! bone mineralization GO:0030282 15 13 0,000 0,01036437 0,02004883 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01036437 0,02003198 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01036437 0,02001516 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01036437 0,01999837 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01036437 0,01998161 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01036437 0,01996487 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01036437 0,01994816 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01036437 0,01993149 ! genitalia development GO:0048806 15 13 0,000 0,01036437 0,01991483 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01036437 0,01989821 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01036437 0,01988162 ! cellular pigmentation GO:0033059 24 13 0,000 0,01036437 0,01986505 ! tissue regeneration GO:0042246 21 13 0,000 0,01036437 0,01984851 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01036437 0,01983199 ! cofactor transport GO:0051181 19 13 0,000 0,01036437 0,01981551 ! NADP metabolic process GO:0006739 18 13 0,000 0,01036437 0,01979905 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01036437 0,01978262 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01036437 0,01976622 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01036437 0,01974984 ! gas transport GO:0015669 18 13 0,000 0,01036437 0,01973349 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01036437 0,01971717 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01036437 0,01970087 ! regulation of axon extension GO:0030516 23 13 0,000 0,01036437 0,0196846 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01036437 0,01966836 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01036437 0,01965215 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01036437 0,01963596 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01036437 0,0196198 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01036437 0,01960367 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01036437 0,01958756 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,01115749 0,02106914 ! superoxide anion generation GO:0042554 18 14 0,000 0,01115749 0,02105186 ! neuron maturation GO:0042551 21 14 0,000 0,01115749 0,0210346 ! regulation of S phase GO:0033261 18 14 0,000 0,01115749 0,02101738 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,01115749 0,02100018 ! myotube differentiation GO:0014902 21 14 0,000 0,01115749 0,02098301 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01115749 0,02096586 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,01115749 0,02094875 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01115749 0,02093166 ! inositol metabolic process GO:0006020 20 14 0,000 0,01115749 0,0209146 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01115749 0,02089757 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01115749 0,02088057 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01115749 0,02086359 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01115749 0,02084664 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01115749 0,02082972 ! response to cAMP GO:0051591 19 14 0,000 0,01115749 0,02081283 ! limbic system development GO:0021761 25 14 0,000 0,01115749 0,02079596 ! startle response GO:0001964 21 14 0,000 0,01115749 0,02077912 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01115749 0,02076231 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01115749 0,02074553 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01115749 0,02072877 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01115749 0,02071204 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01115749 0,02069534 ! glycine metabolic process GO:0006544 22 14 0,000 0,01115749 0,02067866 ! pituitary gland development GO:0021983 23 14 0,000 0,01115749 0,02066201 ! cellular response to starvation GO:0009267 21 14 0,000 0,01115749 0,02064539 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01115749 0,02062879 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01115749 0,02061222 ! regulation of heart rate GO:0002027 23 14 0,000 0,01115749 0,02059568 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01115749 0,02057916 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01115749 0,02056267 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01115749 0,02054621 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01115749 0,02052977 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01115749 0,02051336 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01115749 0,02049698 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01115749 0,02048062 ! axon cargo transport GO:0008088 27 14 0,000 0,01115749 0,02046429 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01115749 0,02044798 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01115749 0,0204317 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01115749 0,02041545 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01115749 0,02039922 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01115749 0,02038302 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01115749 0,02036684 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01115749 0,02035069 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01115749 0,02033456 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01115749 0,02031846 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01115749 0,02030239 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01115749 0,02028634 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01115749 0,02027031 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01115749 0,02025432 ! muscle maintenance GO:0046716 19 14 0,000 0,01115749 0,02023834 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01115749 0,02022239 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01115749 0,02020647 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01115749 0,02019057 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01115749 0,0201747 ! cell killing GO:0001906 20 14 0,000 0,01115749 0,02015885 ! cilium assembly GO:0042384 20 14 0,000 0,01115749 0,02014303 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01115749 0,02012723 ! metencephalon development GO:0022037 19 15 0,000 0,01195001 0,02153999 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01195001 0,02152312 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01195001 0,02150628 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01195001 0,02148946 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01195001 0,02147267 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01195001 0,02145591 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,01195001 0,02143917 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01195001 0,02142246 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01195001 0,02140578 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01195001 0,02138912 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01195001 0,02137249 ! adult walking behavior GO:0007628 25 15 0,000 0,01195001 0,02135588 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01195001 0,0213393 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01195001 0,02132275 ! myoblast differentiation GO:0045445 27 15 0,000 0,01195001 0,02130622 ! centrosome cycle GO:0007098 16 15 0,000 0,01195001 0,02128971 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01195001 0,02127324 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01195001 0,02125678 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01195001 0,02124036 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01195001 0,02122395 ! cerebral cortex development GO:0021987 29 15 0,000 0,01195001 0,02120758 ! response to osmotic stress GO:0006970 22 15 0,000 0,01195001 0,02119123 ! vesicle coating GO:0006901 25 15 0,000 0,01195001 0,0211749 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01195001 0,0211586 ! DNA integration GO:0015074 22 15 0,000 0,01195001 0,02114232 ! peptide secretion GO:0002790 27 15 0,000 0,01195001 0,02112607 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01195001 0,02110985 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01195001 0,02109365 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01195001 0,02107747 ! neuron recognition GO:0008038 22 15 0,000 0,01195001 0,02106132 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01195001 0,02104519 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01195001 0,02102909 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,01195001 0,02101301 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,01195001 0,02099696 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01195001 0,02098093 ! biomineral formation GO:0031214 18 15 0,000 0,01195001 0,02096493 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01195001 0,02094895 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01195001 0,02093299 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01195001 0,02091706 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01195001 0,02090116 ! organic cation transport GO:0015695 19 15 0,000 0,01195001 0,02088527 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01195001 0,02086942 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01195001 0,02085358 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01195001 0,02083777 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01195001 0,02082199 ! defense response to virus GO:0051607 27 15 0,000 0,01195001 0,02080622 ! peptide hormone processing GO:0016486 19 15 0,000 0,01195001 0,02079048 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01195001 0,02077477 ! protein secretion GO:0009306 27 16 0,000 0,01274194 0,02213479 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,01274194 0,02211809 ! hormone secretion GO:0046879 25 16 0,000 0,01274194 0,02210141 ! bone remodeling GO:0046849 24 16 0,000 0,01274194 0,02208475 ! endothelial cell migration GO:0043542 22 16 0,000 0,01274194 0,02206812 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,01274194 0,02205152 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01274194 0,02203494 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01274194 0,02201838 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01274194 0,02200185 ! glial cell development GO:0021782 24 16 0,000 0,01274194 0,02198535 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01274194 0,02196887 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01274194 0,02195241 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01274194 0,02193598 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01274194 0,02191957 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01274194 0,02190319 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01274194 0,02188683 ! fructose metabolic process GO:0006000 20 16 0,000 0,01274194 0,0218705 ! regulation of protein binding GO:0043393 27 16 0,000 0,01274194 0,02185419 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01274194 0,0218379 ! protein export from nucleus GO:0006611 24 16 0,000 0,01274194 0,02182164 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01274194 0,02180541 ! DNA replication initiation GO:0006270 25 16 0,000 0,01274194 0,0217892 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01274194 0,02177301 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01274194 0,02175684 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01274194 0,0217407 ! diencephalon development GO:0021536 25 16 0,000 0,01274194 0,02172459 ! oogenesis GO:0048477 23 16 0,000 0,01274194 0,02170849 ! neural crest cell migration GO:0001755 24 16 0,000 0,01274194 0,02169243 ! G1 phase GO:0051318 27 16 0,000 0,01274194 0,02167638 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01274194 0,02166036 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01274194 0,02164436 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01274194 0,02162839 ! steroid catabolic process GO:0006706 22 16 0,000 0,01274194 0,02161244 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01274194 0,02159651 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01274194 0,02158061 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,01274194 0,02156473 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01274194 0,02154887 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01274194 0,02153304 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01274194 0,02151723 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01274194 0,02150144 ! nerve development GO:0021675 18 16 0,000 0,01274194 0,02148568 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01274194 0,02146994 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01274194 0,02145422 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,01353329 0,02276998 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,01353329 0,02275333 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01353329 0,02273671 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,01353329 0,02272012 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,01353329 0,02270354 ! glycerol metabolic process GO:0006071 20 17 0,000 0,01353329 0,022687 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,01353329 0,02267047 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,01353329 0,02265397 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01353329 0,0226375 ! signal complex assembly GO:0007172 29 17 0,000 0,01353329 0,02262105 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,01353329 0,02260462 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,01353329 0,02258821 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,01353329 0,02257183 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,01353329 0,02255548 ! memory GO:0007613 25 17 0,000 0,01353329 0,02253914 ! keratinization GO:0031424 17 17 0,000 0,01353329 0,02252284 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,01353329 0,02250655 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01353329 0,02249029 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,01353329 0,02247405 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,01353329 0,02245783 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,01353329 0,02244164 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,01353329 0,02242547 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,01353329 0,02240933 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,01353329 0,02239321 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,01353329 0,02237711 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,01353329 0,02236103 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,01353329 0,02234498 ! membrane budding GO:0006900 29 17 0,000 0,01353329 0,02232895 ! heme metabolic process GO:0042168 27 17 0,000 0,01353329 0,02231295 ! actin filament bundle formation GO:0051017 26 17 0,000 0,01353329 0,02229696 ! neuromuscular junction development GO:0007528 23 17 0,000 0,01353329 0,022281 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,01353329 0,02226506 ! body fluid secretion GO:0007589 27 17 0,000 0,01353329 0,02224915 ! stem cell differentiation GO:0048863 36 17 0,000 0,01353329 0,02223326 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01353329 0,02221739 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,01353329 0,02220154 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,01353329 0,02218572 ! sensory perception of pain GO:0019233 23 17 0,000 0,01353329 0,02216991 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,01353329 0,02215413 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,01353329 0,02213838 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,01353329 0,02212264 ! synaptogenesis GO:0007416 24 17 0,000 0,01353329 0,02210693 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01353329 0,02209124 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,01353329 0,02207557 ! cell-cell junction organization GO:0045216 25 17 0,000 0,01353329 0,02205993 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,01353329 0,0220443 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,01353329 0,0220287 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,01353329 0,02201312 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,01353329 0,02199757 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,01353329 0,02198203 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,01353329 0,02196652 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,01432404 0,02323364 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,01432404 0,02321726 ! positive regulation of translation GO:0045727 28 18 0,000 0,01432404 0,02320091 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,01432404 0,02318458 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,01432404 0,02316828 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01432404 0,023152 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,01432404 0,02313574 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01432404 0,02311951 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,01432404 0,02310329 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,01432404 0,0230871 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,01432404 0,02307093 ! axis specification GO:0009798 26 18 0,000 0,01432404 0,02305479 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,01432404 0,02303867 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,01432404 0,02302257 ! pancreas development GO:0031016 26 18 0,000 0,01432404 0,02300649 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,01432404 0,02299044 ! glutamine metabolic process GO:0006541 23 18 0,000 0,01432404 0,0229744 ! response to retinoic acid GO:0032526 25 18 0,000 0,01432404 0,02295839 ! pigmentation during development GO:0048066 31 18 0,000 0,01432404 0,02294241 ! central nervous system neuron development GO:0021954 30 18 0,000 0,01432404 0,02292644 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,01432404 0,0229105 ! fucose metabolic process GO:0006004 26 18 0,000 0,01432404 0,02289458 ! response to fungus GO:0009620 19 18 0,000 0,01432404 0,02287868 ! peptide cross-linking GO:0018149 31 18 0,000 0,01432404 0,0228628 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,01432404 0,02284695 ! heart process GO:0003015 27 18 0,000 0,01432404 0,02283111 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,01432404 0,0228153 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,01432404 0,02279951 ! visual learning GO:0008542 35 18 0,000 0,01432404 0,02278374 ! somitogenesis GO:0001756 24 18 0,000 0,01432404 0,022768 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,01432404 0,02275228 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,01432404 0,02273657 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,01432404 0,02272089 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,01432404 0,02270523 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,01432404 0,0226896 ! vitamin transport GO:0051180 24 18 0,000 0,01432404 0,02267398 ! hormone transport GO:0009914 27 18 0,000 0,01432404 0,02265839 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,01432404 0,02264281 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01432404 0,02262726 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,01432404 0,02261173 ! cell-cell recognition GO:0009988 20 18 0,000 0,01432404 0,02259622 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,01432404 0,02258074 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,01432404 0,02256527 ! regulation of glucose import GO:0046324 21 18 0,000 0,01432404 0,02254983 GO:0010827|regulation of glucose transport, ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,01432404 0,0225344 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,01432404 0,022519 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,01432404 0,02250362 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,01511421 0,02372879 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,01511421 0,0237126 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,01511421 0,02369644 ! positive regulation of ossification GO:0045778 30 19 0,000 0,01511421 0,0236803 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,01511421 0,02366418 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,01511421 0,02364808 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,01511421 0,023632 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,01511421 0,02361595 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,01511421 0,02359992 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,01511421 0,02358391 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,01511421 0,02356792 ! regeneration GO:0031099 32 19 0,000 0,01511421 0,02355195 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,01511421 0,023536 ! response to alkaloid GO:0043279 32 19 0,000 0,01511421 0,02352008 ! sensory perception of taste GO:0050909 23 19 0,000 0,01511421 0,02350418 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,01511421 0,0234883 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,01511421 0,02347244 ! smooth muscle contraction GO:0006939 36 19 0,000 0,01511421 0,0234566 ! peroxisome organization GO:0007031 29 19 0,000 0,01511421 0,02344078 ! digestive system process GO:0022600 30 19 0,000 0,01511421 0,02342498 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,01511421 0,02340921 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,01511421 0,02339346 ! response to vitamin A GO:0033189 26 19 0,000 0,01511421 0,02337773 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,01511421 0,02336201 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,01511421 0,02334632 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,01511421 0,02333066 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,01511421 0,02331501 ! response to starvation GO:0042594 30 19 0,000 0,01511421 0,02329938 ! sex determination GO:0007530 29 19 0,000 0,01511421 0,02328378 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,01511421 0,02326819 ! plasma membrane fusion GO:0045026 23 19 0,000 0,01511421 0,02325263 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,01511421 0,02323708 ! cytolysis GO:0019835 20 19 0,000 0,01511421 0,02322156 ! renal system process GO:0003014 35 19 0,000 0,01511421 0,02320606 ! vasodilation GO:0042311 33 19 0,000 0,01511421 0,02319058 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,01511421 0,02317512 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,01511421 0,02315968 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,01511421 0,02314426 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,01511421 0,02312886 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,01511421 0,02311348 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,01511421 0,02309812 ! sarcomere organization GO:0045214 23 19 0,000 0,01511421 0,02308279 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,01511421 0,02306747 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,01511421 0,02305217 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,01511421 0,0230369 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,01511421 0,02302164 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,01511421 0,0230064 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,01511421 0,02299119 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,01511421 0,02297599 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,01511421 0,02296082 ! protein stabilization GO:0050821 26 19 0,000 0,01511421 0,02294566 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,01590379 0,02412843 ! iron ion transport GO:0006826 37 20 0,000 0,01590379 0,02411253 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,01590379 0,02409664 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,01590379 0,02408078 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,01590379 0,02406494 ! response to vitamin GO:0033273 29 20 0,000 0,01590379 0,02404912 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,01590379 0,02403332 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,01590379 0,02401754 ! spinal cord development GO:0021510 31 20 0,000 0,01590379 0,02400178 ! response to ethanol GO:0045471 37 20 0,000 0,01590379 0,02398604 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,01590379 0,02397032 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,01590379 0,02395462 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,01590379 0,02393894 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,01590379 0,02392329 ! chromosome condensation GO:0030261 31 20 0,000 0,01590379 0,02390765 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,01590379 0,02389204 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,01590379 0,02387644 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,01590379 0,02386087 ! pallium development GO:0021543 38 20 0,000 0,01590379 0,02384531 ! DNA modification GO:0006304 28 20 0,000 0,01590379 0,02382978 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,01590379 0,02381426 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,01590379 0,02379877 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,01590379 0,02378329 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,01590379 0,02376784 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,01590379 0,02375241 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,01590379 0,02373699 ! collagen catabolic process GO:0030574 25 20 0,000 0,01590379 0,0237216 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,01590379 0,02370623 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,01590379 0,02369087 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,01590379 0,02367554 ! alditol metabolic process GO:0019400 24 20 0,000 0,01590379 0,02366022 ! actin filament-based movement GO:0030048 34 20 0,000 0,01590379 0,02364493 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,01669278 0,02480193 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,01669278 0,02478592 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,01669278 0,02476993 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,01669278 0,02475395 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,01669278 0,02473801 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,01669278 0,02472208 ! gluconeogenesis GO:0006094 25 21 0,000 0,01669278 0,02470617 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,01669278 0,02469028 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,01669278 0,02467441 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,01669278 0,02465856 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,01669278 0,02464274 ! protein amino acid acylation GO:0043543 37 21 0,000 0,01669278 0,02462693 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,01669278 0,02461114 ! vesicle docking GO:0048278 27 21 0,000 0,01669278 0,02459538 ! phototransduction GO:0007602 25 21 0,000 0,01669278 0,02457963 ! dendrite development GO:0016358 35 21 0,000 0,01669278 0,02456391 ! visual behavior GO:0007632 39 21 0,000 0,01669278 0,0245482 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,01669278 0,02453251 ! ovarian follicle development GO:0001541 30 21 0,000 0,01669278 0,02451685 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,01669278 0,0245012 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,01669278 0,02448558 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,01669278 0,02446997 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,01669278 0,02445438 ! cell aging GO:0007569 32 21 0,000 0,01669278 0,02443882 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,01669278 0,02442327 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,01669278 0,02440775 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,01669278 0,02439224 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,01669278 0,02437675 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,01669278 0,02436128 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,01669278 0,02434584 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,01669278 0,02433041 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,01669278 0,024315 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,01669278 0,02429961 ! fatty acid transport GO:0015908 30 21 0,000 0,01669278 0,02428424 ! immunoglobulin production GO:0002377 33 21 0,000 0,01669278 0,02426889 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,01669278 0,02425356 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,01669278 0,02423825 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,01669278 0,02422296 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,01669278 0,02420768 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,01669278 0,02419243 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,01669278 0,02417719 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,01669278 0,02416198 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,01669278 0,02414678 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,01669278 0,02413161 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,01669278 0,02411645 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,01669278 0,02410131 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,01669278 0,02408619 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,01669278 0,02407109 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,01669278 0,02405601 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,01669278 0,02404094 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,01748118 0,02516064 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,01748118 0,02514491 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,01748118 0,02512919 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,01748118 0,0251135 ! viral genome replication GO:0019079 29 22 0,000 0,01748118 0,02509782 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,01748118 0,02508217 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,01748118 0,02506653 ! leukocyte adhesion GO:0007159 38 22 0,000 0,01748118 0,02505091 ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,01748118 0,02503531 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,01748118 0,02501973 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,01748118 0,02500417 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,01748118 0,02498863 ! vasculogenesis GO:0001570 33 22 0,000 0,01748118 0,02497311 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,01748118 0,02495761 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,01748118 0,02494213 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,01748118 0,02492666 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,01748118 0,02491122 ! lysosome organization GO:0007040 37 22 0,000 0,01748118 0,0248958 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,01748118 0,02488039 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,01748118 0,024865 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,01748118 0,02484964 ! regulation of behavior GO:0050795 38 22 0,000 0,01748118 0,02483429 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,01748118 0,02481896 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,01748118 0,02480365 ! membrane depolarization GO:0051899 35 22 0,000 0,01748118 0,02478835 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,01748118 0,02477308 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,01748118 0,02475783 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,01748118 0,02474259 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,01748118 0,02472737 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,01748118 0,02471218 ! blastocyst development GO:0001824 37 22 0,000 0,01748118 0,024697 ! neural tube closure GO:0001843 33 22 0,000 0,01748118 0,02468184 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,01748118 0,02466669 ! protein tetramerization GO:0051262 39 22 0,000 0,01748118 0,02465157 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,01826899 0,02574674 ! embryonic pattern specification GO:0009880 31 23 0,000 0,01826899 0,02573098 ! myelination GO:0042552 35 23 0,000 0,01826899 0,02571523 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,01826899 0,0256995 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,01826899 0,02568379 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,01826899 0,0256681 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,01826899 0,02565243 ! vesicle targeting GO:0006903 32 23 0,000 0,01826899 0,02563678 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,01826899 0,02562115 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,01826899 0,02560554 ! osteoblast differentiation GO:0001649 40 23 0,000 0,01826899 0,02558994 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,01826899 0,02557437 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,01826899 0,02555881 ! interaction with host GO:0051701 37 23 0,000 0,01826899 0,02554327 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,01826899 0,02552776 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,01826899 0,02551226 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,01826899 0,02549678 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,01826899 0,02548131 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,01826899 0,02546587 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,01826899 0,02545045 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,01826899 0,02543504 ! cell fate determination GO:0001709 45 23 0,000 0,01826899 0,02541965 ! pentose metabolic process GO:0019321 31 23 0,000 0,01826899 0,02540428 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,01826899 0,02538893 ! spermatid development GO:0007286 33 23 0,000 0,01826899 0,0253736 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,01826899 0,02535829 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,01826899 0,025343 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,01826899 0,02532772 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,01826899 0,02531246 ! telomere organization GO:0032200 32 23 0,000 0,01826899 0,02529722 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,01826899 0,025282 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,01826899 0,0252668 ! regulation of amine transport GO:0051952 38 23 0,000 0,01826899 0,02525161 ! liver development GO:0001889 40 23 0,000 0,01826899 0,02523645 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,01905622 0,02630811 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,01905622 0,02629233 ! initiation of viral infection GO:0019059 42 24 0,000 0,01905622 0,02627657 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,01905622 0,02626082 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,01905622 0,0262451 ! superoxide metabolic process GO:0006801 32 24 0,000 0,01905622 0,02622939 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,01905622 0,0262137 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,01905622 0,02619804 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,01905622 0,02618239 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,01905622 0,02616675 ! sperm motility GO:0030317 27 24 0,000 0,01905622 0,02615114 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,01905622 0,02613555 ! vacuole organization GO:0007033 39 24 0,000 0,01905622 0,02611997 ! receptor metabolic process GO:0043112 37 24 0,000 0,01905622 0,02610442 ! neural crest cell development GO:0014032 39 24 0,000 0,01905622 0,02608888 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,01905622 0,02607336 ! primary neural tube formation GO:0014020 35 24 0,000 0,01905622 0,02605786 ! negative regulation of cell development GO:0010721 56 24 0,000 0,01905622 0,02604237 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,01905622 0,02602691 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,01905622 0,02601146 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,01905622 0,02599603 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,01905622 0,02598062 ! glutathione metabolic process GO:0006749 29 24 0,000 0,01905622 0,02596523 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,01905622 0,02594986 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,01905622 0,02593451 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,01905622 0,02591917 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,01984287 0,02697316 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,01984287 0,02695723 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,01984287 0,02694132 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,01984287 0,02692542 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,01984287 0,02690955 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,01984287 0,02689369 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,01984287 0,02687785 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,01984287 0,02686203 ! peptide transport GO:0015833 43 25 0,000 0,01984287 0,02684623 ! male gonad development GO:0008584 33 25 0,000 0,01984287 0,02683045 ! iron ion homeostasis GO:0055072 39 25 0,000 0,01984287 0,02681468 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,01984287 0,02679894 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,01984287 0,02678321 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,01984287 0,0267675 ! phospholipid transport GO:0015914 35 25 0,000 0,01984287 0,02675181 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,01984287 0,02673614 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,01984287 0,02672049 ! detection of light stimulus GO:0009583 30 25 0,000 0,01984287 0,02670485 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,01984287 0,02668924 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,01984287 0,02667364 ! leukocyte proliferation GO:0070661 39 25 0,000 0,01984287 0,02665806 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,01984287 0,02664249 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,02062892 0,02768175 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,02062892 0,02766561 ! translational initiation GO:0006413 43 26 0,000 0,02062892 0,02764949 ! regulation of pH GO:0006885 36 26 0,000 0,02062892 0,02763339 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,02062892 0,0276173 ! circadian rhythm GO:0007623 42 26 0,000 0,02062892 0,02760124 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,02062892 0,02758519 ! post-embryonic development GO:0009791 42 26 0,000 0,02062892 0,02756916 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,02062892 0,02755315 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,02062892 0,02753716 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,02062892 0,02752119 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,02062892 0,02750523 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,02062892 0,0274893 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,02062892 0,02747338 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,02062892 0,02745748 ! regulation of coagulation GO:0050818 39 26 0,000 0,02062892 0,0274416 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,0214144 0,02847001 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,0214144 0,02845356 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,0214144 0,02843713 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,0214144 0,02842072 ! membrane docking GO:0022406 39 27 0,000 0,0214144 0,02840433 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,0214144 0,02838796 ! catechol metabolic process GO:0009712 43 27 0,000 0,0214144 0,02837161 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,0214144 0,02835527 ! acute-phase response GO:0006953 42 27 0,000 0,0214144 0,02833896 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,0214144 0,02832266 ! myofibril assembly GO:0030239 36 27 0,000 0,0214144 0,02830638 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,0214144 0,02829013 ! response to ionizing radiation GO:0010212 47 27 0,000 0,0214144 0,02827389 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,0214144 0,02825766 ! natural killer cell activation GO:0030101 35 27 0,000 0,0214144 0,02824146 ! lipid oxidation GO:0034440 38 27 0,000 0,0214144 0,02822528 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,0214144 0,02820911 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,0214144 0,02819296 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,0214144 0,02817684 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,0214144 0,02816073 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,0214144 0,02814463 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,0214144 0,02812856 ! gene silencing GO:0016458 41 27 0,000 0,0214144 0,02811251 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,02219928 0,02912627 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,02219928 0,02910966 ! phenol metabolic process GO:0018958 44 28 0,000 0,02219928 0,02909308 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,02219928 0,02907651 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,02219928 0,02905996 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,02219928 0,02904343 ! cell junction assembly GO:0034329 56 28 0,000 0,02219928 0,02902692 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,02219928 0,02901043 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,02219928 0,02899395 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,02219928 0,0289775 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,02219928 0,02896106 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,02219928 0,02894464 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,02219928 0,02892824 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,02219928 0,02891186 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,02219928 0,0288955 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,02219928 0,02887916 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,02219928 0,02886283 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,02219928 0,02884652 ! mesoderm formation GO:0001707 46 28 0,000 0,02219928 0,02883024 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,02219928 0,02881397 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,02219928 0,02879772 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,02219928 0,02878148 ! ensheathment of neurons GO:0007272 43 28 0,000 0,02219928 0,02876527 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,02219928 0,02874907 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,02219928 0,02873289 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,02219928 0,02871673 ! neural tube formation GO:0001841 41 28 0,000 0,02219928 0,02870059 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,02219928 0,02868447 ! placenta development GO:0001890 37 28 0,000 0,02219928 0,02866836 ! regulation of B cell activation GO:0050864 42 28 0,000 0,02219928 0,02865227 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,02298358 0,02964792 ! regulation of innate immune response GO:0045088 38 29 0,000 0,02298358 0,0296313 ! ovulation cycle process GO:0022602 41 29 0,000 0,02298358 0,0296147 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,02298358 0,02959812 ! protein targeting to membrane GO:0006612 53 29 0,000 0,02298358 0,02958156 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,02298358 0,02956501 ! mismatch repair GO:0006298 34 29 0,000 0,02298358 0,02954849 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,02298358 0,02953198 ! muscle cell development GO:0055001 38 29 0,000 0,02298358 0,02951549 ! formation of primary germ layer GO:0001704 48 29 0,000 0,02298358 0,02949902 ! telencephalon development GO:0021537 52 29 0,000 0,02298358 0,02948257 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,02298358 0,02946613 ! eye morphogenesis GO:0048592 51 29 0,000 0,02298358 0,02944972 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,02298358 0,02943332 ! tissue homeostasis GO:0001894 42 29 0,000 0,02298358 0,02941694 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,0237673 0,03040311 ! collagen metabolic process GO:0032963 40 30 0,000 0,0237673 0,03038621 ! organic anion transport GO:0015711 51 30 0,000 0,0237673 0,03036933 ! cholesterol transport GO:0030301 46 30 0,000 0,0237673 0,03035247 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,0237673 0,03033562 ! spliceosome assembly GO:0000245 49 30 0,000 0,0237673 0,0303188 ! spindle organization GO:0007051 37 30 0,000 0,0237673 0,03030199 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,0237673 0,03028521 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,0237673 0,03026844 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,0237673 0,03025169 ! ceramide metabolic process GO:0006672 43 30 0,000 0,0237673 0,03023495 ! ovulation cycle GO:0042698 43 30 0,000 0,0237673 0,03021824 ! hindbrain development GO:0030902 45 30 0,000 0,0237673 0,03020154 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,0237673 0,03018487 ! adult locomotory behavior GO:0008344 47 30 0,000 0,0237673 0,03016821 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,0237673 0,03015157 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,0237673 0,03013495 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,0237673 0,03011834 ! response to heat GO:0009408 41 30 0,000 0,0237673 0,03010176 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,0237673 0,03008519 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,0237673 0,03006864 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,02455044 0,03104233 ! negative regulation of secretion GO:0051048 49 31 0,000 0,02455044 0,03102528 ! mammary gland development GO:0030879 57 31 0,000 0,02455044 0,03100824 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,02455044 0,03099122 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,02455044 0,03097422 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,02455044 0,03095724 ! odontogenesis GO:0042476 50 31 0,000 0,02455044 0,03094028 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,02455044 0,03092333 ! segmentation GO:0035282 41 31 0,000 0,02455044 0,03090641 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,02455044 0,0308895 ! metanephros development GO:0001656 58 31 0,000 0,02455044 0,03087261 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,02455044 0,03085574 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,02455044 0,03083889 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,02455044 0,03082205 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,02455044 0,03080524 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,02455044 0,03078844 ! RNA modification GO:0009451 40 31 0,000 0,02455044 0,03077166 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,02533299 0,03173522 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,02533299 0,03171795 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,02533299 0,03170069 ! meiosis I GO:0007127 52 32 0,000 0,02533299 0,03168345 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,02533299 0,03166623 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,02533299 0,03164903 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,02533299 0,03163185 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,02533299 0,03161469 ! peripheral nervous system development GO:0007422 53 32 0,000 0,02533299 0,03159754 ! regulation of protein stability GO:0031647 48 32 0,000 0,02533299 0,03158042 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,02533299 0,03156331 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,02533299 0,03154622 ! cytokine production GO:0001816 44 32 0,000 0,02533299 0,03152915 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,02533299 0,0315121 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,02533299 0,03149507 ! vesicle localization GO:0051648 47 32 0,000 0,02533299 0,03147805 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,02611496 0,03243218 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,02611496 0,03241468 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,02611496 0,03239719 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,02611496 0,03237973 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,02611496 0,03236228 ! sister chromatid segregation GO:0000819 46 33 0,000 0,02611496 0,03234486 ! ear morphogenesis GO:0042471 42 33 0,000 0,02611496 0,03232745 ! actomyosin structure organization GO:0031032 43 33 0,000 0,02611496 0,03231006 ! cell junction organization GO:0034330 63 33 0,000 0,02611496 0,03229269 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,02611496 0,03227533 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,02611496 0,032258 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,02611496 0,03224069 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,02611496 0,03222339 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,02611496 0,03220611 ! female gonad development GO:0008585 49 33 0,000 0,02611496 0,03218885 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,02611496 0,03217161 ! positive regulation of cell development GO:0010720 54 33 0,000 0,02611496 0,03215439 ! lipid homeostasis GO:0055088 55 33 0,000 0,02611496 0,03213718 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,02611496 0,03212 ! regulation of proteolysis GO:0030162 50 33 0,000 0,02611496 0,03210283 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,02611496 0,03208568 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,02611496 0,03206855 ! cytokinesis GO:0000910 52 33 0,000 0,02611496 0,03205144 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,02611496 0,03203434 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,02689634 0,03297526 ! mRNA catabolic process GO:0006402 48 34 0,000 0,02689634 0,03295769 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,02689634 0,03294014 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,02689634 0,03292261 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,02689634 0,0329051 ! feeding behavior GO:0007631 45 34 0,000 0,02689634 0,0328876 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,02689634 0,03287013 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,02689634 0,03285267 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,02689634 0,03283523 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,02689634 0,03281782 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,02689634 0,03280041 ! neuron migration GO:0001764 46 34 0,000 0,02689634 0,03278303 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,02689634 0,03276567 ! female gamete generation GO:0007292 43 34 0,000 0,02689634 0,03274832 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,02689634 0,032731 ! polyol metabolic process GO:0019751 44 34 0,000 0,02689634 0,03271369 ! aerobic respiration GO:0009060 47 34 0,000 0,02689634 0,0326964 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,02689634 0,03267912 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,02689634 0,03266187 ! embryonic organ development GO:0048568 45 34 0,000 0,02689634 0,03264463 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,02689634 0,03262742 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,02767714 0,03355689 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,02767714 0,03353921 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,02767714 0,03352155 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,02767714 0,03350391 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,02767714 0,03348629 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,02767714 0,03346868 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,02767714 0,03345109 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,02767714 0,03343352 ! pigment metabolic process GO:0042440 61 35 0,000 0,02767714 0,03341597 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,02767714 0,03339844 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,02767714 0,03338093 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,02845736 0,03430395 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,02845736 0,03428598 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,02845736 0,03426803 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,02845736 0,0342501 ! negative regulation of binding GO:0051100 58 36 0,000 0,02845736 0,03423219 ! organic ether metabolic process GO:0018904 46 36 0,000 0,02845736 0,03421429 ! tissue remodeling GO:0048771 62 36 0,000 0,02845736 0,03419642 ! neural tube development GO:0021915 50 36 0,000 0,02845736 0,03417856 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,02845736 0,03416072 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,02845736 0,0341429 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,02845736 0,0341251 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,02845736 0,03410732 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,029237 0,03502349 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,029237 0,03500526 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,029237 0,03498705 ! learning GO:0007612 67 37 0,000 0,029237 0,03496886 ! ion transmembrane transport GO:0034220 56 37 0,000 0,029237 0,03495068 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,029237 0,03493252 ! regulation of protein secretion GO:0050708 51 37 0,000 0,029237 0,03491439 ! amino acid activation GO:0043038 52 37 0,000 0,029237 0,03489627 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,029237 0,03487817 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,03001606 0,03578898 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,03001606 0,03577044 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,03001606 0,03575191 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,03001606 0,03573341 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,03001606 0,03571492 ! phagocytosis GO:0006909 60 38 0,000 0,03001606 0,03569646 ! pigmentation GO:0043473 74 38 0,000 0,03001606 0,03567801 ! maintenance of location in cell GO:0051651 69 38 0,000 0,03001606 0,03565958 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,03079454 0,03656554 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,03079454 0,03654667 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,03079454 0,03652782 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,03079454 0,03650899 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,03079454 0,03649018 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,03079454 0,03647139 ! male sex differentiation GO:0046661 53 39 0,000 0,03079454 0,03645262 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,03079454 0,03643387 ! chromatin remodeling GO:0006338 68 39 0,000 0,03079454 0,03641514 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,03079454 0,03639643 ! JNK cascade GO:0007254 54 39 0,000 0,03079454 0,03637773 ! cell growth GO:0016049 61 39 0,000 0,03079454 0,03635906 ! synapse organization GO:0050808 55 39 0,000 0,03079454 0,0363404 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,03157244 0,03723929 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,03157244 0,0372202 ! regulation of tube size GO:0035150 60 40 0,000 0,03157244 0,03720113 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,03157244 0,03718208 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,03157244 0,03716306 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,03157244 0,03714405 ! peptide metabolic process GO:0006518 56 40 0,000 0,03157244 0,03712506 ! inner ear development GO:0048839 57 40 0,000 0,03157244 0,03710609 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,03157244 0,03708714 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,03157244 0,0370682 ! B cell differentiation GO:0030183 62 40 0,000 0,03157244 0,03704929 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,03157244 0,0370304 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,03157244 0,03701152 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,03234976 0,03790344 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,03234976 0,03788414 ! glucose transport GO:0015758 52 41 0,000 0,03234976 0,03786486 ! endosome transport GO:0016197 71 41 0,000 0,03234976 0,0378456 ! striated muscle contraction GO:0006941 62 41 0,000 0,03234976 0,03782636 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,03234976 0,03780714 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,03234976 0,03778793 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,03234976 0,03776875 ! biopolymer methylation GO:0043414 62 41 0,000 0,03234976 0,03774959 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,03234976 0,03773045 ! mitochondrial transport GO:0006839 60 42 0,000 0,0331265 0,0386168 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,0331265 0,03859724 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,0331265 0,03857769 ! cellular component disassembly GO:0022411 64 42 0,000 0,0331265 0,03855817 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,0331265 0,03853867 ! hexose transport GO:0008645 54 42 0,000 0,0331265 0,03851918 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 0,000 0,0331265 0,03849972 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,0331265 0,03848027 ! excretion GO:0007588 63 42 0,000 0,0331265 0,03846085 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,0331265 0,03844144 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,0331265 0,03842206 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,0331265 0,03840269 ! regulation of cell shape GO:0008360 78 42 0,000 0,0331265 0,03838335 ! positive regulation of binding GO:0051099 59 43 0,000 0,03390266 0,0392629 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,03390266 0,03924314 ! leukocyte migration GO:0050900 60 43 0,000 0,03390266 0,0392234 ! neuromuscular process GO:0050905 79 43 0,000 0,03390266 0,03920368 ! activation of caspase activity GO:0006919 65 43 0,000 0,03390266 0,03918398 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,03390266 0,03916429 ! tRNA processing GO:0008033 49 43 0,000 0,03390266 0,03914463 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,03390266 0,03912499 ! vesicle organization GO:0016050 79 43 0,000 0,03390266 0,03910537 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,03390266 0,03908577 ! methylation GO:0032259 64 43 0,000 0,03390266 0,03906619 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,03467824 0,03993988 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,03467824 0,03991989 ! glycolysis GO:0006096 53 44 0,000 0,03467824 0,03989992 ! regulation of action potential GO:0001508 71 44 0,000 0,03467824 0,03987997 ! regulation of ion transport GO:0043269 57 44 0,000 0,03467824 0,03986004 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,03467824 0,03984013 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,03467824 0,03982024 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,03467824 0,03980037 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,03467824 0,03978052 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,03467824 0,03976069 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,03467824 0,03974088 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,03467824 0,03972109 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,03467824 0,03970132 ! RNA catabolic process GO:0006401 64 45 0,000 0,03545324 0,04056839 ! positive regulation of defense response GO:0031349 59 45 0,000 0,03545324 0,04054821 ! regulation of translational initiation GO:0006446 64 45 0,000 0,03545324 0,04052806 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,03545324 0,04050793 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,03545324 0,04048781 ! cell recognition GO:0008037 58 45 0,000 0,03545324 0,04046772 ! cell maturation GO:0048469 60 45 0,000 0,03545324 0,04044765 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,03545324 0,04042759 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,03622767 0,0412902 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,03622767 0,04126975 ! cell redox homeostasis GO:0045454 63 46 0,000 0,03622767 0,04124932 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,03622767 0,04122891 ! regulation of ossification GO:0030278 71 46 0,000 0,03622767 0,04120852 ! histone modification GO:0016570 68 46 0,000 0,03622767 0,04118815 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,03622767 0,0411678 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,03700151 0,04202641 ! viral infectious cycle GO:0019058 71 47 0,000 0,03700151 0,04200567 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,03700151 0,04198494 ! endocrine system development GO:0035270 83 47 0,000 0,03700151 0,04196424 ! covalent chromatin modification GO:0016569 75 47 0,000 0,03700151 0,04194356 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,03700151 0,0419229 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,03700151 0,04190226 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,03700151 0,04188164 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,03700151 0,04186103 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,03700151 0,04184045 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,03700151 0,04181989 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,03700151 0,04179935 ! chloride transport GO:0006821 67 48 0,000 0,03777479 0,04265194 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,03777479 0,04263101 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,03777479 0,04261011 ! response to temperature stimulus GO:0009266 62 48 0,000 0,03777479 0,04258922 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,03777479 0,04256835 ! gastrulation GO:0007369 73 48 0,000 0,03777479 0,04254751 ! heart morphogenesis GO:0003007 65 48 0,000 0,03777479 0,04252668 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,03777479 0,04250587 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,03777479 0,04248509 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,03777479 0,04246432 ! regulation of endocytosis GO:0030100 63 48 0,000 0,03777479 0,04244358 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,03777479 0,04242285 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,03777479 0,04240215 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,03854748 0,04324839 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,03854748 0,04322731 ! sensory perception of smell GO:0007608 61 49 0,000 0,03854748 0,04320624 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,03854748 0,04318519 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,03854748 0,04316417 ! RNA elongation GO:0006354 62 49 0,000 0,03854748 0,04314316 ! germ cell development GO:0007281 68 49 0,000 0,03854748 0,04312218 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,03854748 0,04310122 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,03854748 0,04308027 ! cartilage development GO:0051216 70 49 0,000 0,03854748 0,04305935 ! maintenance of location GO:0051235 84 49 0,000 0,03854748 0,04303845 ! regulation of actin filament length GO:0030832 72 50 0,000 0,0393196 0,04387922 ! ear development GO:0043583 72 50 0,000 0,0393196 0,04385794 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,0393196 0,04383668 ! membrane fusion GO:0006944 80 50 0,000 0,0393196 0,04381544 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,0393196 0,04379423 ! lipid modification GO:0030258 73 50 0,000 0,0393196 0,04377303 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,0393196 0,04375185 ! proton transport GO:0015992 75 50 0,000 0,0393196 0,04373069 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,0393196 0,04370956 ! positive regulation of secretion GO:0051047 71 51 0,000 0,04009114 0,04454571 ! hydrogen transport GO:0006818 77 51 0,000 0,04009114 0,0445242 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,04009114 0,04450271 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,04009114 0,04448125 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,04009114 0,0444598 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,04009114 0,04443837 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,04009114 0,04441697 ! adult behavior GO:0030534 80 51 0,000 0,04009114 0,04439558 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,04009114 0,04437422 ! transition metal ion transport GO:0000041 74 52 0,000 0,04086211 0,04520579 ! regulation of cellular component size GO:0032535 74 52 0,000 0,04086211 0,04518406 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,04086211 0,04516235 ! aging GO:0007568 79 52 0,000 0,04086211 0,04514066 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,04086211 0,04511899 ! establishment of organelle localization GO:0051656 85 52 0,000 0,04086211 0,04509734 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,0416325 0,04592554 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,0416325 0,04590352 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,0416325 0,04588153 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,0416325 0,04585955 ! kidney development GO:0001822 90 53 0,000 0,0416325 0,0458376 ! single fertilization GO:0007338 59 53 0,000 0,0416325 0,04581567 ! cell projection assembly GO:0030031 76 53 0,000 0,0416325 0,04579376 ! amino acid transport GO:0006865 84 54 0,000 0,04240232 0,04661823 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,04240232 0,04659595 ! regulation of mitosis GO:0007088 84 54 0,000 0,04240232 0,0465737 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,04240232 0,04655147 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,04240232 0,04652926 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,04240232 0,04650707 ! DNA catabolic process GO:0006308 67 54 0,000 0,04240232 0,0464849 ! detection of external stimulus GO:0009581 66 54 0,000 0,04240232 0,04646276 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,04240232 0,04644063 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,04240232 0,04641853 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,04240232 0,04639645 ! exocytosis GO:0006887 74 55 0,000 0,04317156 0,04721569 ! mesoderm development GO:0007498 76 55 0,000 0,04317156 0,04719324 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,04317156 0,04717082 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,04317156 0,04714843 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,04394023 0,04796513 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,04394023 0,04794237 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,04394023 0,04791964 ! carbohydrate transport GO:0008643 74 57 0,000 0,04470832 0,04873419 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,04470832 0,04871111 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,04470832 0,04868804 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,04470832 0,048665 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,04470832 0,04864198 ! camera-type eye development GO:0043010 88 57 0,000 0,04470832 0,04861898 ! secondary metabolic process GO:0019748 84 57 0,000 0,04470832 0,048596 ! gonad development GO:0008406 79 57 0,000 0,04470832 0,04857305 ! viral reproductive process GO:0022415 87 58 0,000 0,04547585 0,04938359 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,04547585 0,04936029 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,04547585 0,049337 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,04547585 0,04931374 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,0462428 0,05012179 ! activation of MAPK activity GO:0000187 84 59 0,000 0,0462428 0,05009818 ! actin filament organization GO:0007015 95 59 0,000 0,0462428 0,05007459 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,0462428 0,05005103 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,0462428 0,05002749 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,04700917 0,05083268 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,04700917 0,05080879 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,04700917 0,05078492 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,04700917 0,05076108 ! regulation of heart contraction GO:0008016 91 60 0,000 0,04700917 0,05073726 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,04700917 0,05071346 ! fertilization GO:0009566 68 60 0,000 0,04700917 0,05068969 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,04700917 0,05066593 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,04777498 0,05146719 ! meiosis GO:0007126 96 61 0,000 0,04777498 0,0514431 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,04777498 0,05141902 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,04777498 0,05139497 ! urogenital system development GO:0001655 101 61 0,000 0,04777498 0,05137095 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,04777498 0,05134694 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,04777498 0,05132296 ! extracellular matrix organization GO:0030198 103 61 0,000 0,04777498 0,051299 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,04777498 0,05127506 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,04854022 0,05207206 ! neurotransmitter transport GO:0006836 81 62 0,000 0,04854022 0,05204778 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,04854022 0,05202353 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,04854022 0,0519993 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,04854022 0,05197509 ! meiotic cell cycle GO:0051321 97 62 0,000 0,04854022 0,05195091 ! organelle localization GO:0051640 96 62 0,000 0,04854022 0,05192674 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,04930488 0,05272023 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,04930488 0,05269573 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,04930488 0,05267126 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,04930488 0,05264681 ! viral reproduction GO:0016032 92 63 0,000 0,04930488 0,05262238 ! regulation of lipase activity GO:0060191 109 63 0,000 0,04930488 0,05259797 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,05006897 0,05338833 ! negative regulation of cell size GO:0045792 108 64 0,000 0,05006897 0,05336359 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,05006897 0,05333888 ! hexose catabolic process GO:0019320 82 64 0,000 0,05006897 0,05331418 ! adaptive immune response GO:0002250 94 64 0,000 0,05006897 0,05328951 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,05083249 0,05407712 ! B cell activation GO:0042113 104 65 0,000 0,05083249 0,05405212 ! defense response to bacterium GO:0042742 73 65 0,000 0,05083249 0,05402714 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,05083249 0,05400219 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,05083249 0,05397726 ! activation of immune response GO:0002253 83 65 0,000 0,05083249 0,05395235 ! protein oligomerization GO:0051259 100 65 0,000 0,05083249 0,05392746 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,05159545 0,05471163 ! antigen processing and presentation GO:0019882 96 66 0,000 0,05159545 0,05468642 ! axon guidance GO:0007411 99 66 0,000 0,05159545 0,05466123 ! regulation of immune effector process GO:0002697 101 66 0,000 0,05159545 0,05463606 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,05235783 0,05541786 ! acute inflammatory response GO:0002526 92 68 0,000 0,05311964 0,05619834 ! learning or memory GO:0007611 123 68 0,000 0,05311964 0,0561725 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,05311964 0,05614668 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,05311964 0,05612089 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,05311964 0,05609512 ! rhythmic process GO:0048511 105 68 0,000 0,05311964 0,05606938 ! inorganic anion transport GO:0015698 93 68 0,000 0,05311964 0,05604366 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,05388089 0,05682074 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,05388089 0,0567947 ! response to drug GO:0042493 108 69 0,000 0,05388089 0,05676869 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,05464157 0,05754377 ! humoral immune response GO:0006959 86 70 0,000 0,05464157 0,05751744 ! eye development GO:0001654 111 70 0,000 0,05464157 0,05749113 ! amine transport GO:0015837 101 70 0,000 0,05464157 0,05746484 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,05464157 0,05743857 ! regulation of catabolic process GO:0009894 106 70 0,000 0,05464157 0,05741234 ! muscle cell differentiation GO:0042692 104 71 0,000 0,05540167 0,05818441 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,05540167 0,05815785 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,05540167 0,05813132 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,05540167 0,05810481 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,05540167 0,05807833 ! response to hypoxia GO:0001666 132 72 0,000 0,05616122 0,05884774 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,05616122 0,05882095 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,05616122 0,05879417 ! negative regulation of transport GO:0051051 116 73 0,000 0,05692019 0,05956162 ! regulation of blood pressure GO:0008217 107 73 0,000 0,05692019 0,05953453 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,05692019 0,05950747 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,05692019 0,05948044 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,0576786 0,06024558 ! response to oxygen levels GO:0070482 137 74 0,000 0,0576786 0,06021824 ! digestion GO:0007586 97 74 0,000 0,0576786 0,06019091 ! protein import into nucleus GO:0006606 118 74 0,000 0,0576786 0,06016362 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,0576786 0,06013634 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,0576786 0,0601091 ! blood coagulation GO:0007596 116 75 0,000 0,05843644 0,06087129 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,05843644 0,06084374 ! response to nutrient GO:0007584 104 75 0,000 0,05843644 0,0608162 ! nuclear import GO:0051170 121 75 0,000 0,05843644 0,0607887 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,05843644 0,06076122 ! amine biosynthetic process GO:0009309 97 76 0,000 0,05919371 0,06152081 ! tRNA metabolic process GO:0006399 95 76 0,000 0,05919371 0,06149302 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,05919371 0,06146526 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,05995042 0,06222291 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,05995042 0,06219485 ! regulation of DNA binding GO:0051101 119 77 0,000 0,05995042 0,06216681 ! gland development GO:0048732 148 77 0,000 0,05995042 0,06213879 ! sex differentiation GO:0007548 105 77 0,000 0,05995042 0,0621108 ! protein ubiquitination GO:0016567 125 77 0,000 0,05995042 0,06208283 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,05995042 0,06205489 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,05995042 0,06202698 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,05995042 0,06199909 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,06070657 0,06275286 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,06070657 0,06272467 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,06146215 0,06347685 ! cellular respiration GO:0045333 107 79 0,000 0,06146215 0,06344836 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,06146215 0,06341989 ! T cell activation GO:0042110 134 79 0,000 0,06146215 0,06339145 ! regulation of lyase activity GO:0051339 133 79 0,000 0,06146215 0,06336304 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,06146215 0,06333465 ! chromatin assembly GO:0031497 102 80 0,000 0,06221716 0,06408396 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,06221716 0,06405527 ! protein localization in nucleus GO:0034504 133 80 0,000 0,06221716 0,06402661 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,06297161 0,06477402 ! hemostasis GO:0007599 125 81 0,000 0,06297161 0,06474507 ! mRNA transport GO:0051028 121 81 0,000 0,06297161 0,06471614 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,06297161 0,06468723 ! regulation of neurological system process GO:0031644 122 81 0,000 0,06297161 0,06465835 ! vitamin metabolic process GO:0006766 103 81 0,000 0,06297161 0,0646295 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,06297161 0,06460068 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,0637255 0,06534492 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,0637255 0,0653158 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,06447883 0,06605849 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,06447883 0,06602907 ! regulation of defense response GO:0031347 117 84 0,000 0,06523159 0,06677021 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,06523159 0,0667405 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,06523159 0,06671083 ! sterol metabolic process GO:0016125 120 84 0,000 0,06523159 0,06668118 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,06598379 0,06742013 ! rRNA metabolic process GO:0016072 107 85 0,000 0,06598379 0,06739019 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,06598379 0,06736028 ! transcription initiation GO:0006352 118 85 0,000 0,06598379 0,06733039 ! regulation of membrane potential GO:0042391 128 85 0,000 0,06598379 0,06730054 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,06673542 0,068037 ! nucleosome organization GO:0034728 114 87 0,000 0,0674865 0,06877224 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,0674865 0,06874178 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,0674865 0,06871135 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,0674865 0,06868095 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,0674865 0,06865057 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,06823701 0,06938335 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,06823701 0,06935269 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,06823701 0,06932205 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,06823701 0,06929145 ! reproductive developmental process GO:0003006 127 89 0,000 0,06898697 0,07002207 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,06898697 0,06999119 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,06898697 0,06996033 ! regulation of T cell activation GO:0050863 128 89 0,000 0,06898697 0,06992949 ! leukocyte differentiation GO:0002521 143 90 0,000 0,06973636 0,07065798 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,06973636 0,07062687 ! hormone metabolic process GO:0042445 121 90 0,000 0,06973636 0,07059579 ! ATP metabolic process GO:0046034 137 91 0,000 0,07048519 0,07132245 ! response to virus GO:0009615 122 91 0,000 0,07048519 0,07129109 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,07123346 0,07201625 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,07123346 0,07198461 ! positive regulation of immune response GO:0050778 121 92 0,000 0,07123346 0,07195299 ! DNA recombination GO:0006310 146 92 0,000 0,07123346 0,07192141 ! sulfur metabolic process GO:0006790 118 92 0,000 0,07123346 0,07188985 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,07198118 0,07261259 ! electron transport chain GO:0022900 123 94 0,000 0,07272833 0,07333413 ! response to oxidative stress GO:0006979 141 94 0,000 0,07272833 0,073302 ! regulation of binding GO:0051098 151 95 0,000 0,07347493 0,07402205 ! carboxylic acid transport GO:0046942 147 95 0,000 0,07347493 0,07398964 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,07422096 0,07470819 ! in utero embryonic development GO:0001701 147 96 0,000 0,07422096 0,07467551 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,07422096 0,07464286 ! protein maturation GO:0051604 129 96 0,000 0,07422096 0,07461023 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,07496644 0,0753267 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,07496644 0,07529381 ! calcium ion transport GO:0006816 167 99 0,000 0,07645573 0,07675608 ! extracellular structure organization GO:0043062 156 99 0,000 0,07645573 0,07672259 ! protein import GO:0017038 156 99 0,000 0,07645573 0,07668913 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,07719954 0,07740146 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,07719954 0,07736773 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,07719954 0,07733403 ! divalent metal ion transport GO:0070838 171 100 0,000 0,07719954 0,07730036 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,07719954 0,07726673 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,07719954 0,07723312 ! protein localization in organelle GO:0033365 161 100 0,000 0,07719954 0,07719954