pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/2932-3-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 1,549E-08 3,727E-05 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 2,284E-07 2,747E-04 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 3,25E-07 2,606E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,498E-06 9,009E-04 ! response to UV GO:0009411 104 53 2,000 2,307E-06 1,11E-03 ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 2,313E-06 9,276E-04 ! anagen GO:0042640 6 5 1,000 2,313E-06 7,951E-04 ! regulation of keratinocyte differentiation GO:0045616 6 5 1,000 2,313E-06 6,957E-04 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 2,313E-06 6,184E-04 GO:0032862|activation of Rho GTPase activity, ! stem cell division GO:0017145 11 5 1,000 2,313E-06 5,566E-04 GO:0048103|somatic stem cell division, ! hair follicle maturation GO:0048820 7 6 1,000 3,469E-06 7,588E-04 ! ectodermal gut morphogenesis GO:0048567 12 6 1,000 3,469E-06 6,955E-04 GO:0007439|ectodermal gut development, ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,855E-06 8,986E-04 ! regulation of myoblast differentiation GO:0045661 16 7 1,000 4,855E-06 8,344E-04 ! regulation of epidermal cell differentiation GO:0045604 8 7 1,000 4,855E-06 7,788E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 6,472E-06 9,732E-04 ! negative regulation of muscle cell differentiation GO:0051148 15 8 1,000 6,472E-06 9,159E-04 ! ER overload response GO:0006983 12 8 1,000 6,472E-06 8,651E-04 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 6,472E-06 8,195E-04 ! positive regulation of epidermis development GO:0045684 13 8 1,000 6,472E-06 7,785E-04 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 6,605E-06 7,568E-04 ! keratinocyte proliferation GO:0043616 14 9 1,000 8,318E-06 9,097E-04 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 8,318E-06 8,702E-04 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,039E-05 1,042E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,039E-05 1E-03 ! endoderm development GO:0007492 16 10 1,000 1,039E-05 9,619E-04 ! regulation of stress fiber formation GO:0051492 30 10 1,000 1,039E-05 9,263E-04 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 1,039E-05 8,932E-04 ! UV protection GO:0009650 19 11 1,000 1,27E-05 1,054E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 1,27E-05 1,019E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,346E-05 1,045E-03 ! interphase GO:0051325 213 98 2,000 1,478E-05 1,111E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,524E-05 1,111E-03 ! digestive tract morphogenesis GO:0048546 26 12 1,000 1,524E-05 1,078E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,8E-05 1,238E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 1,8E-05 1,203E-03 ! regulation of epidermis development GO:0045682 19 13 1,000 1,8E-05 1,171E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 2,1E-05 1,329E-03 ! hair follicle morphogenesis GO:0031069 26 14 1,000 2,1E-05 1,295E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 2,1E-05 1,263E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 2,1E-05 1,232E-03 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 2,422E-05 1,387E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 2,422E-05 1,355E-03 ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 2,422E-05 1,324E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 2,422E-05 1,295E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 2,767E-05 1,447E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 2,767E-05 1,417E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 2,767E-05 1,387E-03 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 3,135E-05 1,539E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 3,135E-05 1,509E-03 ! epidermis morphogenesis GO:0048730 40 18 1,000 3,526E-05 1,664E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 3,526E-05 1,632E-03 ! skin development GO:0043588 36 19 1,000 3,94E-05 1,789E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 3,94E-05 1,755E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 4,376E-05 1,914E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 4,376E-05 1,88E-03 ! peptidyl-serine modification GO:0018209 43 20 1,000 4,376E-05 1,847E-03 ! negative regulation of translation GO:0017148 29 20 1,000 4,376E-05 1,815E-03 ! hindlimb morphogenesis GO:0035137 43 21 1,000 4,836E-05 1,972E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 4,836E-05 1,939E-03 ! gut development GO:0048565 39 21 1,000 4,836E-05 1,907E-03 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 5,318E-05 2,064E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 5,822E-05 2,224E-03 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell adhesion GO:0045785 56 23 1,000 5,822E-05 2,189E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 6,9E-05 2,554E-03 ! molting cycle process GO:0022404 50 26 1,000 7,473E-05 2,724E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! neuron fate commitment GO:0048663 48 27 1,000 8,068E-05 2,897E-03 ! fat cell differentiation GO:0045444 50 27 1,000 8,068E-05 2,855E-03 ! base-excision repair GO:0006284 41 27 1,000 8,068E-05 2,813E-03 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 8,068E-05 2,773E-03 ! negative regulation of protein modification process GO:0031400 60 28 1,000 8,687E-05 2,944E-03 ! determination of left/right symmetry GO:0007368 47 30 1,000 9,991E-05 3,339E-03 ! determination of bilateral symmetry GO:0009855 49 31 1,000 1,068E-04 3,519E-03 GO:0009799|determination of symmetry, ! cell fate specification GO:0001708 52 33 1,000 1,212E-04 3,939E-03 ! glial cell differentiation GO:0010001 63 34 1,000 1,287E-04 4,129E-03 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 1,287E-04 4,074E-03 ! regulation of muscle development GO:0048634 70 35 1,000 1,365E-04 4,264E-03 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 1,365E-04 4,209E-03 ! RNA export from nucleus GO:0006405 56 37 1,000 1,527E-04 4,649E-03 ! glycogen metabolic process GO:0005977 61 37 1,000 1,527E-04 4,591E-03 ! glucan metabolic process GO:0044042 62 38 1,000 1,611E-04 4,785E-03 GO:0006073|cellular glucan metabolic process, ! mesenchymal cell development GO:0014031 87 40 1,000 1,786E-04 5,241E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! gliogenesis GO:0042063 88 41 1,000 1,877E-04 5,442E-03 ! keratinocyte differentiation GO:0030216 62 41 1,000 1,877E-04 5,377E-03 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 1,971E-04 5,578E-03 ! energy reserve metabolic process GO:0006112 74 43 1,000 2,066E-04 5,781E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 2,066E-04 5,714E-03 ! double-strand break repair GO:0006302 81 44 1,000 2,164E-04 5,917E-03 ! developmental growth GO:0048589 82 44 1,000 2,164E-04 5,85E-03 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 2,264E-04 6,052E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 2,264E-04 5,986E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 2,366E-04 6,188E-03 ! epidermal cell differentiation GO:0009913 68 46 1,000 2,366E-04 6,122E-03 ! response to insulin stimulus GO:0032868 95 46 1,000 2,366E-04 6,056E-03 ! positive regulation of protein transport GO:0051222 72 46 1,000 2,366E-04 5,993E-03 ! response to calcium ion GO:0051592 81 47 1,000 2,471E-04 6,192E-03 ! positive regulation of cell cycle GO:0045787 89 48 1,000 2,577E-04 6,393E-03 ! Notch signaling pathway GO:0007219 96 48 1,000 2,577E-04 6,328E-03 ! positive regulation of growth GO:0045927 90 52 1,000 3,026E-04 7,355E-03 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 3,026E-04 7,281E-03 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 3,386E-04 8,067E-03 ! nuclear export GO:0051168 97 55 1,000 3,386E-04 7,987E-03 ! nucleotide-excision repair GO:0006289 83 56 1,000 3,511E-04 8,201E-03 ! regulation of DNA replication GO:0006275 101 56 1,000 3,511E-04 8,122E-03 ! regulation of intracellular transport GO:0032386 101 57 1,000 3,637E-04 8,334E-03 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 4,03E-04 9,148E-03 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 4,166E-04 9,367E-03 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 4,729E-04 0,01053594 GO:0035113|embryonic appendage morphogenesis, ! developmental maturation GO:0021700 116 66 1,000 4,876E-04 0,01076241 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 5,024E-04 0,01098955 ! lung development GO:0030324 144 67 1,000 5,024E-04 0,01089054 ! negative regulation of kinase activity GO:0033673 131 68 1,000 5,175E-04 0,01111718 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 5,175E-04 0,01101879 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 5,328E-04 0,01124494 ! appendage morphogenesis GO:0035107 135 70 1,000 5,483E-04 0,01147171 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 5,483E-04 0,01137282 ! appendage development GO:0048736 136 71 1,000 5,64E-04 0,01159911 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 1,000 5,8E-04 0,011826 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 5,8E-04 0,01172663 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 5,8E-04 0,0116289 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 5,8E-04 0,0115328 ! negative regulation of transferase activity GO:0051348 140 72 1,000 5,8E-04 0,01143827 ! respiratory system development GO:0060541 153 72 1,000 5,8E-04 0,01134527 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 6,125E-04 0,01188536 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 6,125E-04 0,01179028 ! regulation of actin filament-based process GO:0032970 152 77 1,000 6,63E-04 0,01266014 ! positive regulation of ligase activity GO:0051351 124 77 1,000 6,63E-04 0,01256045 ! regulation of peptidase activity GO:0052547 134 79 1,000 6,977E-04 0,01311495 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 6,977E-04 0,01301328 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 6,977E-04 0,01291318 ! response to metal ion GO:0010038 140 80 1,000 7,154E-04 0,01313941 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 7,333E-04 0,01336615 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of neuron differentiation GO:0045664 167 81 1,000 7,333E-04 0,01326565 ! regulation of ligase activity GO:0051340 142 84 1,000 7,883E-04 0,01415412 ! response to unfolded protein GO:0006986 131 85 1,000 8,071E-04 0,01438368 ! response to inorganic substance GO:0010035 153 86 1,000 8,26E-04 0,01461366 ! tube morphogenesis GO:0035239 176 86 1,000 8,26E-04 0,014507 ! mitochondrion organization GO:0007005 148 86 1,000 8,26E-04 0,01440187 ! regulation of protein transport GO:0051223 154 87 1,000 8,452E-04 0,01463048 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 1,000 8,646E-04 0,01485952 ! regulation of cell adhesion GO:0030155 212 89 1,000 8,843E-04 0,01508897 ! response to protein stimulus GO:0051789 149 91 1,000 9,242E-04 0,01565856 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 9,649E-04 0,01623459 GO:0010498|proteasomal protein catabolic process, ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 9,649E-04 0,01612185 ! forebrain development GO:0030900 188 95 1,000 1,006E-03 0,01670091 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 1,006E-03 0,01658652 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 1,049E-03 0,01716851 ! regulation of protein localization GO:0032880 176 97 1,000 1,049E-03 0,01705251 ! cell cycle arrest GO:0007050 213 100 1,000 1,114E-03 0,01799208 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 2,488E-03 0,0399071 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 2,488E-03 0,03964281 ! positive regulation of helicase activity GO:0051096 11 5 0,000 2,488E-03 0,039382 ! neuron fate determination GO:0048664 7 5 0,000 2,488E-03 0,0391246 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,488E-03 0,03887055 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 2,488E-03 0,03861977 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 2,488E-03 0,03837221 ! polyol transport GO:0015791 12 5 0,000 2,488E-03 0,0381278 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 2,488E-03 0,03788648 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 2,488E-03 0,0376482 ! response to superoxide GO:0000303 10 5 0,000 2,488E-03 0,0374129 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,488E-03 0,03718052 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 2,488E-03 0,03695101 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 2,488E-03 0,03672432 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 2,488E-03 0,03650039 ! female meiosis GO:0007143 7 5 0,000 2,488E-03 0,03627918 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 2,488E-03 0,03606063 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 2,488E-03 0,0358447 ! cobalt ion transport GO:0006824 11 5 0,000 2,488E-03 0,03563134 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 2,488E-03 0,0354205 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 2,488E-03 0,03521214 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 2,488E-03 0,03500622 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 2,488E-03 0,0348027 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 2,488E-03 0,03460153 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 2,488E-03 0,03440267 ! embryonic camera-type eye development GO:0031076 10 5 0,000 2,488E-03 0,03420608 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 2,488E-03 0,03401173 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 2,488E-03 0,03381957 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 2,488E-03 0,03362958 ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,488E-03 0,0334417 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 2,488E-03 0,03325591 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 2,488E-03 0,03307218 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 2,488E-03 0,03289046 ! negative chemotaxis GO:0050919 14 5 0,000 2,488E-03 0,03271073 ! positive regulation of histone modification GO:0031058 5 5 0,000 2,488E-03 0,03253296 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 2,488E-03 0,0323571 ! sensory perception of bitter taste GO:0050913 7 5 0,000 2,488E-03 0,03218314 ! behavioral response to pain GO:0048266 9 5 0,000 2,488E-03 0,03201104 ! clathrin coat assembly GO:0048268 14 5 0,000 2,488E-03 0,03184077 ! Notch receptor processing GO:0007220 8 5 0,000 2,488E-03 0,0316723 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,488E-03 0,0315056 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 2,488E-03 0,03134065 ! micturition GO:0060073 9 5 0,000 2,488E-03 0,03117742 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 2,488E-03 0,03101588 ! copulation GO:0007620 9 5 0,000 2,488E-03 0,030856 ! glial cell fate commitment GO:0021781 13 5 0,000 2,488E-03 0,03069777 ! protein maturation by protein folding GO:0022417 13 5 0,000 2,488E-03 0,03054114 ! spermidine metabolic process GO:0008216 7 5 0,000 2,488E-03 0,03038611 ! regulation of potassium ion transport GO:0043266 10 5 0,000 2,488E-03 0,03023265 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 2,488E-03 0,03008073 ! apoptotic cell clearance GO:0043277 20 5 0,000 2,488E-03 0,02993032 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 2,488E-03 0,02978141 ! lipoprotein particle clearance GO:0034381 10 5 0,000 2,488E-03 0,02963398 ! grooming behavior GO:0007625 6 5 0,000 2,488E-03 0,029488 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 2,488E-03 0,02934345 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 2,488E-03 0,02920031 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,488E-03 0,02905856 ! response to protozoan GO:0001562 10 5 0,000 2,488E-03 0,02891819 ! positive regulation of glycolysis GO:0045821 14 5 0,000 2,488E-03 0,02877916 ! lymph vessel development GO:0001945 10 5 0,000 2,488E-03 0,02864146 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 2,488E-03 0,02850507 ! endochondral ossification GO:0001958 16 5 0,000 2,488E-03 0,02836997 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 2,488E-03 0,02823615 ! parathyroid gland development GO:0060017 13 5 0,000 2,488E-03 0,02810359 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 2,488E-03 0,02797226 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 2,488E-03 0,02784216 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 2,488E-03 0,02771326 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 2,488E-03 0,02758555 ! dorsal spinal cord development GO:0021516 7 5 0,000 2,488E-03 0,02745901 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 2,488E-03 0,02733363 ! sphingoid catabolic process GO:0046521 6 5 0,000 2,488E-03 0,02720938 ! skeletal myofibril assembly GO:0014866 10 5 0,000 2,488E-03 0,02708626 ! smooth muscle tissue development GO:0048745 28 5 0,000 2,488E-03 0,02696425 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 2,488E-03 0,02684334 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 2,488E-03 0,0267235 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 2,488E-03 0,02660473 ! cardiac muscle fiber development GO:0048739 10 5 0,000 2,488E-03 0,02648701 ! transepithelial chloride transport GO:0030321 9 5 0,000 2,488E-03 0,02637033 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 2,488E-03 0,02625467 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 2,488E-03 0,02614002 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 2,488E-03 0,02602637 ! neutrophil mediated immunity GO:0002446 7 5 0,000 2,488E-03 0,0259137 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 2,488E-03 0,025802 ! histidine catabolic process GO:0006548 6 5 0,000 2,488E-03 0,02569126 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 2,488E-03 0,02558147 ! microvillus organization GO:0032528 7 5 0,000 2,488E-03 0,02547261 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 2,488E-03 0,02536468 ! L-serine biosynthetic process GO:0006564 6 5 0,000 2,488E-03 0,02525766 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 2,488E-03 0,02515153 ! tryptophan metabolic process GO:0006568 9 5 0,000 2,488E-03 0,02504629 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 2,488E-03 0,02494193 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 2,488E-03 0,02483844 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 2,488E-03 0,0247358 ! polyol catabolic process GO:0046174 7 5 0,000 2,488E-03 0,02463401 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 2,488E-03 0,02453305 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 2,488E-03 0,02443292 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 2,488E-03 0,0243336 ! muscle cell migration GO:0014812 8 5 0,000 2,488E-03 0,02423508 ! mitochondrial fission GO:0000266 8 5 0,000 2,488E-03 0,02413736 ! sister chromatid cohesion GO:0007062 12 5 0,000 2,488E-03 0,02404042 ! mRNA transcription GO:0009299 9 5 0,000 2,488E-03 0,02394426 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 2,488E-03 0,02384886 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 2,488E-03 0,02375422 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 2,488E-03 0,02366033 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 2,488E-03 0,02356718 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 2,488E-03 0,02347476 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 2,488E-03 0,02338306 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 2,488E-03 0,02329208 ! response to food GO:0032094 6 5 0,000 2,488E-03 0,0232018 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 2,488E-03 0,02311222 ! positive regulation of transporter activity GO:0032411 8 5 0,000 2,488E-03 0,02302332 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 2,488E-03 0,02293511 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,488E-03 0,02284757 ! paraxial mesoderm development GO:0048339 14 5 0,000 2,488E-03 0,0227607 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 2,488E-03 0,02267449 ! forebrain neuron development GO:0021884 13 5 0,000 2,488E-03 0,02258892 ! lipoprotein catabolic process GO:0042159 11 5 0,000 2,488E-03 0,022504 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 2,488E-03 0,02241972 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 2,488E-03 0,02233606 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,488E-03 0,02225303 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 2,488E-03 0,02217061 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 2,488E-03 0,0220888 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,488E-03 0,02200759 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 2,488E-03 0,02192698 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 2,488E-03 0,02184695 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 2,488E-03 0,02176751 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 2,488E-03 0,02168864 ! basic amino acid transport GO:0015802 11 5 0,000 2,488E-03 0,02161034 ! cellular glucose homeostasis GO:0001678 5 5 0,000 2,488E-03 0,02153261 ! early endosome to late endosome transport GO:0045022 12 5 0,000 2,488E-03 0,02145543 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,488E-03 0,0213788 ! depyrimidination GO:0045008 10 5 0,000 2,488E-03 0,02130272 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 2,488E-03 0,02122718 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,488E-03 0,02115217 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 2,488E-03 0,02107769 ! zinc ion homeostasis GO:0055069 8 5 0,000 2,488E-03 0,02100373 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 2,488E-03 0,0209303 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 2,488E-03 0,02085737 ! forebrain morphogenesis GO:0048853 13 5 0,000 2,488E-03 0,02078495 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 2,488E-03 0,02071303 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 2,488E-03 0,0206416 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 2,488E-03 0,02057067 ! peptidyl-arginine modification GO:0018195 9 5 0,000 2,488E-03 0,02050022 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,488E-03 0,02043025 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,488E-03 0,02036076 ! response to arsenic GO:0046685 10 5 0,000 2,488E-03 0,02029174 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 2,488E-03 0,02022319 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 2,488E-03 0,0201551 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 2,488E-03 0,02008746 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 2,488E-03 0,02002028 ! response to cadmium ion GO:0046686 7 5 0,000 2,488E-03 0,01995355 ! bile acid biosynthetic process GO:0006699 6 5 0,000 2,488E-03 0,01988726 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 2,488E-03 0,01982141 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 2,488E-03 0,01975599 ! decidualization GO:0046697 11 5 0,000 2,488E-03 0,019691 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 2,488E-03 0,01962644 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 2,488E-03 0,0195623 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 2,488E-03 0,01949858 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 2,488E-03 0,01943527 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 2,488E-03 0,01937238 ! base conversion or substitution editing GO:0016553 5 5 0,000 2,488E-03 0,01930989 ! neural tube patterning GO:0021532 7 5 0,000 2,488E-03 0,0192478 ! embryonic cleavage GO:0040016 6 5 0,000 2,488E-03 0,0191861 ! peroxisome fission GO:0016559 5 5 0,000 2,488E-03 0,01912481 ! histone demethylation GO:0016577 10 5 0,000 2,488E-03 0,0190639 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 2,488E-03 0,01900338 ! mitotic recombination GO:0006312 9 5 0,000 2,488E-03 0,01894324 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,488E-03 0,01888348 ! metaphase plate congression GO:0051310 7 5 0,000 2,488E-03 0,0188241 ! regulation of sterol transport GO:0032371 7 5 0,000 2,488E-03 0,01876509 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 2,488E-03 0,01870645 ! enteric nervous system development GO:0048484 8 5 0,000 2,488E-03 0,01864818 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 2,488E-03 0,01859026 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 2,488E-03 0,01853271 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 2,488E-03 0,01847551 ! muscle cell proliferation GO:0033002 11 5 0,000 2,488E-03 0,01841866 ! skeletal muscle regeneration GO:0043403 8 5 0,000 2,488E-03 0,01836216 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 2,488E-03 0,01830601 ! plasminogen activation GO:0031639 5 5 0,000 2,488E-03 0,0182502 ! B cell homeostasis GO:0001782 13 5 0,000 2,488E-03 0,01819472 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 2,488E-03 0,01813959 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 2,488E-03 0,01808479 ! metaphase GO:0051323 8 5 0,000 2,488E-03 0,01803031 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 2,488E-03 0,01797617 ! cellular response to nutrient GO:0031670 8 5 0,000 2,488E-03 0,01792235 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 2,488E-03 0,01786885 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 2,488E-03 0,01781567 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 2,488E-03 0,0177628 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 2,488E-03 0,01771025 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 2,488E-03 0,01765801 ! response to redox state GO:0051775 5 5 0,000 2,488E-03 0,01760607 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 2,488E-03 0,01755444 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 2,488E-03 0,01750311 ! regulation of telomerase activity GO:0051972 6 5 0,000 2,488E-03 0,01745208 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,488E-03 0,01740135 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 2,488E-03 0,01735091 ! porphyrin catabolic process GO:0006787 12 5 0,000 2,488E-03 0,01730076 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 2,488E-03 0,01725091 ! striatum development GO:0021756 9 5 0,000 2,488E-03 0,01720133 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 2,488E-03 0,01715205 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 2,488E-03 0,01710304 ! glial cell migration GO:0008347 11 5 0,000 2,488E-03 0,01705431 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 2,488E-03 0,01700586 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 2,488E-03 0,01695769 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 2,488E-03 0,01690979 ! somatic stem cell maintenance GO:0035019 15 5 0,000 2,488E-03 0,01686215 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 2,488E-03 0,01681479 ! negative regulation of lipase activity GO:0060192 8 5 0,000 2,488E-03 0,01676769 ! neuroprotection GO:0043526 6 5 0,000 2,488E-03 0,01672085 ! neural plate development GO:0001840 8 5 0,000 2,488E-03 0,01667427 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 2,488E-03 0,01662796 ! regulation of sensory perception GO:0051931 7 5 0,000 2,488E-03 0,0165819 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 2,488E-03 0,01653609 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 2,488E-03 0,01649054 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 2,488E-03 0,01644523 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 2,488E-03 0,01640018 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 2,488E-03 0,01635537 ! sequestering of calcium ion GO:0051208 7 5 0,000 2,488E-03 0,0163108 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 2,488E-03 0,01626648 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 2,488E-03 0,0162224 ! spindle assembly GO:0051225 6 5 0,000 2,488E-03 0,01617855 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 2,488E-03 0,01613494 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 2,488E-03 0,01609157 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 2,488E-03 0,01604843 ! drug metabolic process GO:0017144 6 5 0,000 2,488E-03 0,01600552 ! phospholipid scrambling GO:0017121 8 5 0,000 2,488E-03 0,01596284 ! organ regeneration GO:0031100 7 5 0,000 2,488E-03 0,01592038 ! carnitine metabolic process GO:0009437 7 5 0,000 2,488E-03 0,01587815 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 2,488E-03 0,01583615 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 2,488E-03 0,01579437 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 2,985E-03 0,01889897 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 2,985E-03 0,01884936 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 2,985E-03 0,01880002 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 2,985E-03 0,01875093 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 2,985E-03 0,0187021 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 2,985E-03 0,01865353 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 2,985E-03 0,0186052 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 2,985E-03 0,01855713 ! sleep GO:0030431 13 6 0,000 2,985E-03 0,0185093 ! response to oxygen radical GO:0000305 11 6 0,000 2,985E-03 0,01846172 ! positive regulation of axon extension GO:0045773 11 6 0,000 2,985E-03 0,01841438 ! myoblast cell fate commitment GO:0048625 16 6 0,000 2,985E-03 0,01836728 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 2,985E-03 0,01832043 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 2,985E-03 0,01827381 ! regulation of interferon-beta production GO:0032648 8 6 0,000 2,985E-03 0,01822743 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 2,985E-03 0,01818129 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 2,985E-03 0,01813537 ! forebrain regionalization GO:0021871 8 6 0,000 2,985E-03 0,01808969 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 2,985E-03 0,01804424 ! male meiosis GO:0007140 7 6 0,000 2,985E-03 0,01799902 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 2,985E-03 0,01795402 ! response to zinc ion GO:0010043 9 6 0,000 2,985E-03 0,01790925 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 2,985E-03 0,0178647 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 2,985E-03 0,01782037 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 2,985E-03 0,01777626 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 2,985E-03 0,01773237 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 2,985E-03 0,01768869 ! malate metabolic process GO:0006108 11 6 0,000 2,985E-03 0,01764523 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 2,985E-03 0,01760198 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 2,985E-03 0,01755894 ! protein refolding GO:0042026 15 6 0,000 2,985E-03 0,01751612 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 2,985E-03 0,0174735 ! opsonization GO:0008228 8 6 0,000 2,985E-03 0,01743109 ! mating behavior GO:0007617 7 6 0,000 2,985E-03 0,01738888 ! neuron remodeling GO:0016322 15 6 0,000 2,985E-03 0,01734688 ! erythrocyte maturation GO:0043249 7 6 0,000 2,985E-03 0,01730508 ! embryonic hemopoiesis GO:0035162 14 6 0,000 2,985E-03 0,01726348 ! equilibrioception GO:0050957 14 6 0,000 2,985E-03 0,01722208 ! protein amino acid dealkylation GO:0008214 12 6 0,000 2,985E-03 0,01718088 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 2,985E-03 0,01713988 ! photoreceptor cell development GO:0042461 10 6 0,000 2,985E-03 0,01709907 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 2,985E-03 0,01705845 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 2,985E-03 0,01701803 ! response to interferon-gamma GO:0034341 15 6 0,000 2,985E-03 0,0169778 ! toxin metabolic process GO:0009404 11 6 0,000 2,985E-03 0,01693775 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 2,985E-03 0,0168979 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 2,985E-03 0,01685823 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 2,985E-03 0,01681875 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 2,985E-03 0,01677946 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 2,985E-03 0,01674034 ! cGMP-mediated signaling GO:0019934 13 6 0,000 2,985E-03 0,01670141 ! activation of MAPKKK activity GO:0000185 12 6 0,000 2,985E-03 0,01666266 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 2,985E-03 0,01662409 ! thymic T cell selection GO:0045061 12 6 0,000 2,985E-03 0,0165857 ! protein lipoylation GO:0009249 10 6 0,000 2,985E-03 0,01654748 ! cysteine metabolic process GO:0006534 10 6 0,000 2,985E-03 0,01650944 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 2,985E-03 0,01647158 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 2,985E-03 0,01643389 ! glutamate catabolic process GO:0006538 10 6 0,000 2,985E-03 0,01639637 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 2,985E-03 0,01635902 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 2,985E-03 0,01632184 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 2,985E-03 0,01628483 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 2,985E-03 0,01624798 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 2,985E-03 0,0162113 ! hyperosmotic response GO:0006972 9 6 0,000 2,985E-03 0,01617479 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 2,985E-03 0,01613844 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 2,985E-03 0,01610226 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 2,985E-03 0,01606624 ! urea metabolic process GO:0019627 7 6 0,000 2,985E-03 0,01603037 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 2,985E-03 0,01599467 ! neutrophil activation GO:0042119 8 6 0,000 2,985E-03 0,01595913 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 2,985E-03 0,01592374 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 2,985E-03 0,01588851 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 2,985E-03 0,01585344 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 2,985E-03 0,01581852 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 2,985E-03 0,01578375 ! neuron apoptosis GO:0051402 9 6 0,000 2,985E-03 0,01574914 ! nucleoside salvage GO:0043174 9 6 0,000 2,985E-03 0,01571468 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 2,985E-03 0,01568037 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 2,985E-03 0,0156462 ! T cell mediated immunity GO:0002456 16 6 0,000 2,985E-03 0,01561219 ! negative regulation of platelet activation GO:0010544 9 6 0,000 2,985E-03 0,01557833 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 2,985E-03 0,01554461 ! carnitine transport GO:0015879 10 6 0,000 2,985E-03 0,01551103 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 2,985E-03 0,0154776 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,985E-03 0,01544432 ! positive regulation of exocytosis GO:0045921 8 6 0,000 2,985E-03 0,01541118 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 2,985E-03 0,01537818 ! 5S class rRNA transcription GO:0042791 11 6 0,000 2,985E-03 0,01534532 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 2,985E-03 0,0153126 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 2,985E-03 0,01528002 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 2,985E-03 0,01524758 ! sodium ion homeostasis GO:0055078 11 6 0,000 2,985E-03 0,01521527 ! establishment of spindle localization GO:0051293 12 6 0,000 2,985E-03 0,0151831 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 2,985E-03 0,01515107 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 2,985E-03 0,01511917 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 2,985E-03 0,01508741 ! neural nucleus development GO:0048857 14 6 0,000 2,985E-03 0,01505578 ! response to UV-C GO:0010225 11 6 0,000 2,985E-03 0,01502428 ! astrocyte development GO:0014002 15 6 0,000 2,985E-03 0,01499292 ! protein targeting to lysosome GO:0006622 10 6 0,000 2,985E-03 0,01496168 ! purine base biosynthetic process GO:0009113 17 6 0,000 2,985E-03 0,01493058 ! interaction with symbiont GO:0051702 13 6 0,000 2,985E-03 0,0148996 ! regulation of dendrite development GO:0050773 16 6 0,000 2,985E-03 0,01486875 ! skeletal muscle contraction GO:0003009 6 6 0,000 2,985E-03 0,01483803 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 2,985E-03 0,01480744 ! response to copper ion GO:0046688 10 6 0,000 2,985E-03 0,01477697 ! response to exogenous dsRNA GO:0043330 10 6 0,000 2,985E-03 0,01474663 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 2,985E-03 0,01471641 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,985E-03 0,01468631 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 2,985E-03 0,01465634 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 2,985E-03 0,01462649 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 2,985E-03 0,01459676 ! regulation of dopamine secretion GO:0014059 14 6 0,000 2,985E-03 0,01456716 ! nucleoside catabolic process GO:0009164 7 6 0,000 2,985E-03 0,01453767 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 2,985E-03 0,0145083 ! Schwann cell development GO:0014044 15 6 0,000 2,985E-03 0,01447905 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 2,985E-03 0,01444992 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 2,985E-03 0,0144209 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 2,985E-03 0,014392 ! subpallium development GO:0021544 10 6 0,000 2,985E-03 0,01436322 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 2,985E-03 0,01433455 ! histone ubiquitination GO:0016574 8 6 0,000 2,985E-03 0,01430599 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 2,985E-03 0,01427755 ! maintenance of organ identity GO:0048496 9 6 0,000 2,985E-03 0,01424922 ! G2 phase GO:0051319 16 6 0,000 2,985E-03 0,01422101 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 2,985E-03 0,0141929 ! establishment of planar polarity GO:0001736 7 6 0,000 2,985E-03 0,01416491 ! regulation of mast cell activation GO:0033003 12 6 0,000 2,985E-03 0,01413702 ! membrane to membrane docking GO:0022614 14 6 0,000 2,985E-03 0,01410925 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 2,985E-03 0,01408158 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 2,985E-03 0,01405403 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 2,985E-03 0,01402658 ! receptor internalization GO:0031623 10 6 0,000 2,985E-03 0,01399924 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 2,985E-03 0,013972 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 2,985E-03 0,01394487 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,985E-03 0,01391784 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 2,985E-03 0,01389092 ! protein deubiquitination GO:0016579 14 6 0,000 2,985E-03 0,01386411 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 2,985E-03 0,01383739 ! protein destabilization GO:0031648 9 6 0,000 2,985E-03 0,01381078 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 2,985E-03 0,01378428 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 2,985E-03 0,01375787 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 2,985E-03 0,01373156 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 2,985E-03 0,01370536 ! progesterone metabolic process GO:0042448 10 6 0,000 2,985E-03 0,01367925 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 2,985E-03 0,01365325 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 2,985E-03 0,01362734 ! negative regulation of axon extension GO:0030517 21 6 0,000 2,985E-03 0,01360153 ! removal of superoxide radicals GO:0019430 11 6 0,000 2,985E-03 0,01357582 ! triglyceride catabolic process GO:0019433 10 6 0,000 2,985E-03 0,0135502 ! determination of adult lifespan GO:0008340 15 6 0,000 2,985E-03 0,01352469 ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 2,985E-03 0,01349926 ! cerebellar cortex formation GO:0021697 8 6 0,000 2,985E-03 0,01347394 ! catecholamine transport GO:0051937 9 6 0,000 2,985E-03 0,0134487 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 2,985E-03 0,01342357 ! sensory cilium assembly GO:0035058 10 6 0,000 2,985E-03 0,01339852 ! organ or tissue specific immune response GO:0002251 7 6 0,000 2,985E-03 0,01337357 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 2,985E-03 0,01334871 ! maternal placenta development GO:0001893 12 6 0,000 2,985E-03 0,01332395 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 2,985E-03 0,01329927 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 2,985E-03 0,01327469 ! negative regulation of B cell activation GO:0050869 13 6 0,000 2,985E-03 0,0132502 ! protein amino acid prenylation GO:0018346 16 6 0,000 2,985E-03 0,0132258 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 2,985E-03 0,01320149 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 2,985E-03 0,01317726 ! positive regulation of coagulation GO:0050820 12 6 0,000 2,985E-03 0,01315313 ! tRNA transcription GO:0009304 14 7 0,000 3,482E-03 0,0153137 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 3,482E-03 0,01528576 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 3,482E-03 0,01525792 ! behavioral response to cocaine GO:0048148 14 7 0,000 3,482E-03 0,01523017 ! regulation of helicase activity GO:0051095 15 7 0,000 3,482E-03 0,01520253 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 3,482E-03 0,01517499 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 3,482E-03 0,01514755 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 3,482E-03 0,01512021 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 3,482E-03 0,01509297 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 3,482E-03 0,01506582 ! prostate gland development GO:0030850 13 7 0,000 3,482E-03 0,01503877 ! nucleotide-sugar transport GO:0015780 12 7 0,000 3,482E-03 0,01501182 ! synaptonemal complex assembly GO:0007130 10 7 0,000 3,482E-03 0,01498497 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 3,482E-03 0,01495821 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 3,482E-03 0,01493154 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 3,482E-03 0,01490497 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 3,482E-03 0,0148785 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 3,482E-03 0,01485212 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 3,482E-03 0,01482583 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 3,482E-03 0,01479964 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 3,482E-03 0,01477354 ! SMAD protein complex assembly GO:0007183 12 7 0,000 3,482E-03 0,01474753 ! glycolipid transport GO:0046836 10 7 0,000 3,482E-03 0,01472161 ! protein amino acid sulfation GO:0006477 10 7 0,000 3,482E-03 0,01469578 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 3,482E-03 0,01467005 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 3,482E-03 0,0146444 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 3,482E-03 0,01461884 ! actin-myosin filament sliding GO:0033275 11 7 0,000 3,482E-03 0,01459337 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 3,482E-03 0,01456799 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 3,482E-03 0,0145427 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 3,482E-03 0,0145175 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 3,482E-03 0,01449238 ! mRNA stabilization GO:0048255 18 7 0,000 3,482E-03 0,01446735 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 3,482E-03 0,01444241 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 3,482E-03 0,01441755 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 3,482E-03 0,01439278 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 3,482E-03 0,01436809 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 3,482E-03 0,01434349 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 3,482E-03 0,01431897 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 3,482E-03 0,01429453 ! lipoprotein transport GO:0042953 14 7 0,000 3,482E-03 0,01427018 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 3,482E-03 0,01424591 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 3,482E-03 0,01422172 ! rhythmic behavior GO:0007622 15 7 0,000 3,482E-03 0,01419762 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 3,482E-03 0,0141736 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 3,482E-03 0,01414965 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 3,482E-03 0,01412579 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 3,482E-03 0,01410201 ! regulation of odontogenesis GO:0042481 13 7 0,000 3,482E-03 0,01407831 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 3,482E-03 0,01405469 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 3,482E-03 0,01403115 ! mechanosensory behavior GO:0007638 14 7 0,000 3,482E-03 0,01400769 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 3,482E-03 0,0139843 ! positive regulation of isotype switching GO:0045830 15 7 0,000 3,482E-03 0,01396099 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 3,482E-03 0,01393776 ! protein-cofactor linkage GO:0018065 13 7 0,000 3,482E-03 0,01391461 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 3,482E-03 0,01389154 ! spinal cord patterning GO:0021511 13 7 0,000 3,482E-03 0,01386854 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 3,482E-03 0,01384561 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 3,482E-03 0,01382277 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 3,482E-03 0,01379999 ! adrenal gland development GO:0030325 17 7 0,000 3,482E-03 0,0137773 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 3,482E-03 0,01375467 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 3,482E-03 0,01373212 ! ovulation GO:0030728 9 7 0,000 3,482E-03 0,01370965 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 3,482E-03 0,01368725 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 3,482E-03 0,01366492 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 3,482E-03 0,01364266 ! microtubule nucleation GO:0007020 20 7 0,000 3,482E-03 0,01362048 ! proline biosynthetic process GO:0006561 10 7 0,000 3,482E-03 0,01359837 ! thyroid hormone generation GO:0006590 13 7 0,000 3,482E-03 0,01357633 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 3,482E-03 0,01355436 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 3,482E-03 0,01353246 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 3,482E-03 0,01351064 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 3,482E-03 0,01348888 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 3,482E-03 0,0134672 ! galactose metabolic process GO:0006012 13 7 0,000 3,482E-03 0,01344558 ! vesicle fusion GO:0006906 17 7 0,000 3,482E-03 0,01342403 ! response to dietary excess GO:0002021 8 7 0,000 3,482E-03 0,01340255 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 3,482E-03 0,01338114 ! intracellular pH reduction GO:0051452 11 7 0,000 3,482E-03 0,0133598 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 3,482E-03 0,01333853 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 3,482E-03 0,01331732 ! organ growth GO:0035265 15 7 0,000 3,482E-03 0,01329618 ! purine salvage GO:0043101 10 7 0,000 3,482E-03 0,01327511 ! nucleoside transport GO:0015858 8 7 0,000 3,482E-03 0,01325411 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 3,482E-03 0,01323317 ! parturition GO:0007567 14 7 0,000 3,482E-03 0,0132123 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 3,482E-03 0,01319149 ! rRNA modification GO:0000154 14 7 0,000 3,482E-03 0,01317075 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 3,482E-03 0,01315007 ! spindle checkpoint GO:0031577 15 7 0,000 3,482E-03 0,01312946 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 3,482E-03 0,01310891 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 3,482E-03 0,01308843 ! macrophage differentiation GO:0030225 11 7 0,000 3,482E-03 0,01306801 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 3,482E-03 0,01304766 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 3,482E-03 0,01302737 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 3,482E-03 0,01300714 ! hyaluronan metabolic process GO:0030212 8 7 0,000 3,482E-03 0,01298697 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 3,482E-03 0,01296687 ! anterograde axon cargo transport GO:0008089 18 7 0,000 3,482E-03 0,01294682 ! fibrinolysis GO:0042730 10 7 0,000 3,482E-03 0,01292685 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 3,482E-03 0,01290693 ! eating behavior GO:0042755 7 7 0,000 3,482E-03 0,01288707 ! B cell lineage commitment GO:0002326 21 7 0,000 3,482E-03 0,01286727 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 3,482E-03 0,01284754 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 3,482E-03 0,01282786 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 3,482E-03 0,01280825 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 3,482E-03 0,0127887 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 3,482E-03 0,0127692 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 3,482E-03 0,01274977 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 3,482E-03 0,01273039 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 3,482E-03 0,01271107 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 3,482E-03 0,01269181 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 3,482E-03 0,01267261 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 3,482E-03 0,01265347 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 3,482E-03 0,01263438 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 3,482E-03 0,01261536 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 3,482E-03 0,01259638 ! regulation of meiosis GO:0040020 12 7 0,000 3,482E-03 0,01257747 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 3,482E-03 0,01255861 ! T cell lineage commitment GO:0002360 16 7 0,000 3,482E-03 0,01253981 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 3,482E-03 0,01252107 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 3,482E-03 0,01250238 ! oxygen homeostasis GO:0032364 12 7 0,000 3,482E-03 0,01248375 ! transcription termination GO:0006353 13 7 0,000 3,482E-03 0,01246517 ! response to tumor cell GO:0002347 13 7 0,000 3,482E-03 0,01244665 ! regulation of respiratory burst GO:0060263 11 7 0,000 3,482E-03 0,01242818 ! coenzyme A metabolic process GO:0015936 12 7 0,000 3,482E-03 0,01240977 ! anaphase GO:0051322 17 7 0,000 3,482E-03 0,01239141 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 3,482E-03 0,01237311 ! axonal fasciculation GO:0007413 18 7 0,000 3,482E-03 0,01235486 ! negative regulation of nuclear division GO:0051784 14 7 0,000 3,482E-03 0,01233667 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 3,482E-03 0,01231852 ! peptidyl-threonine modification GO:0018210 25 7 0,000 3,482E-03 0,01230043 ! diuresis GO:0030146 12 7 0,000 3,482E-03 0,0122824 GO:0030147|natriuresis, ! thiamin metabolic process GO:0006772 7 7 0,000 3,482E-03 0,01226442 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 3,482E-03 0,01224648 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 3,482E-03 0,01222861 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 3,482E-03 0,01221078 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 3,482E-03 0,01219301 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 3,482E-03 0,01217528 ! melanin biosynthetic process GO:0042438 8 7 0,000 3,482E-03 0,01215761 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 3,482E-03 0,01213999 ! dopamine biosynthetic process GO:0042416 18 7 0,000 3,482E-03 0,01212243 ! glycolipid catabolic process GO:0019377 15 7 0,000 3,482E-03 0,01210491 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 3,482E-03 0,01208744 ! lymph node development GO:0048535 10 7 0,000 3,482E-03 0,01207002 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 3,482E-03 0,01205266 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 3,482E-03 0,01203534 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 3,482E-03 0,01201807 ! endosome to lysosome transport GO:0008333 11 7 0,000 3,482E-03 0,01200085 ! protein modification by small protein removal GO:0070646 16 7 0,000 3,482E-03 0,01198368 ! adult feeding behavior GO:0008343 9 7 0,000 3,482E-03 0,01196657 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 3,482E-03 0,01194949 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 3,482E-03 0,01193247 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 3,482E-03 0,0119155 ! muscle adaptation GO:0043500 14 7 0,000 3,482E-03 0,01189857 ! embryonic heart tube development GO:0035050 10 7 0,000 3,482E-03 0,0118817 ! retina homeostasis GO:0001895 12 7 0,000 3,482E-03 0,01186487 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 3,482E-03 0,01184808 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 3,482E-03 0,01183135 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 3,482E-03 0,01181466 ! protein prenylation GO:0018342 18 7 0,000 3,482E-03 0,01179802 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 3,482E-03 0,01178143 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 3,482E-03 0,01176488 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 3,482E-03 0,01174838 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 3,978E-03 0,0134048 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 3,978E-03 0,01338605 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 3,978E-03 0,01336736 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 3,978E-03 0,01334871 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 3,978E-03 0,01333012 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 3,978E-03 0,01331158 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 3,978E-03 0,01329309 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 3,978E-03 0,01327466 ! neutral lipid catabolic process GO:0046461 13 8 0,000 3,978E-03 0,01325627 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 3,978E-03 0,01323794 ! meiotic prophase I GO:0007128 13 8 0,000 3,978E-03 0,01321965 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 3,978E-03 0,01320142 ! oligopeptide transport GO:0006857 15 8 0,000 3,978E-03 0,01318323 ! UTP metabolic process GO:0046051 8 8 0,000 3,978E-03 0,0131651 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 3,978E-03 0,01314702 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 3,978E-03 0,01312898 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 3,978E-03 0,013111 ! macrophage chemotaxis GO:0048246 12 8 0,000 3,978E-03 0,01309306 ! succinate metabolic process GO:0006105 14 8 0,000 3,978E-03 0,01307517 ! membrane hyperpolarization GO:0060081 10 8 0,000 3,978E-03 0,01305734 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 3,978E-03 0,01303955 ! T-helper 1 type immune response GO:0042088 12 8 0,000 3,978E-03 0,01302181 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 3,978E-03 0,01300411 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 3,978E-03 0,01298647 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 3,978E-03 0,01296887 ! ganglioside metabolic process GO:0001573 19 8 0,000 3,978E-03 0,01295132 ! reflex GO:0060004 16 8 0,000 3,978E-03 0,01293382 ! negative regulation of endocytosis GO:0045806 11 8 0,000 3,978E-03 0,01291637 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 3,978E-03 0,01289896 ! endothelial cell differentiation GO:0045446 17 8 0,000 3,978E-03 0,0128816 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 3,978E-03 0,01286428 ! glycerolipid catabolic process GO:0046503 13 8 0,000 3,978E-03 0,01284702 ! hemoglobin metabolic process GO:0020027 13 8 0,000 3,978E-03 0,0128298 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 3,978E-03 0,01281262 ! pigment granule organization GO:0048753 16 8 0,000 3,978E-03 0,01279549 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 3,978E-03 0,01277841 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 3,978E-03 0,01276137 ! astrocyte differentiation GO:0048708 18 8 0,000 3,978E-03 0,01274438 ! histidine metabolic process GO:0006547 16 8 0,000 3,978E-03 0,01272743 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 3,978E-03 0,01271053 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 3,978E-03 0,01269367 ! glycine catabolic process GO:0006546 13 8 0,000 3,978E-03 0,01267686 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 3,978E-03 0,01266009 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 3,978E-03 0,01264337 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 3,978E-03 0,01262669 ! regulation of pigmentation during development GO:0048070 24 8 0,000 3,978E-03 0,01261005 ! melanin metabolic process GO:0006582 15 8 0,000 3,978E-03 0,01259346 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 3,978E-03 0,01257691 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 3,978E-03 0,0125604 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 3,978E-03 0,01254394 ! macrophage activation GO:0042116 12 8 0,000 3,978E-03 0,01252752 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 3,978E-03 0,01251115 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 3,978E-03 0,01249481 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 3,978E-03 0,01247852 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 3,978E-03 0,01246228 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 3,978E-03 0,01244607 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 3,978E-03 0,01242991 ! regulation of vascular permeability GO:0043114 12 8 0,000 3,978E-03 0,01241378 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 3,978E-03 0,0123977 ! osteoblast development GO:0002076 16 8 0,000 3,978E-03 0,01238167 ! positive regulation of vasodilation GO:0045909 13 8 0,000 3,978E-03 0,01236567 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 3,978E-03 0,01234971 ! negative regulation of translational initiation GO:0045947 10 8 0,000 3,978E-03 0,0123338 ! Schwann cell differentiation GO:0014037 19 8 0,000 3,978E-03 0,01231793 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 3,978E-03 0,01230209 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 3,978E-03 0,0122863 ! response to UV-B GO:0010224 16 8 0,000 3,978E-03 0,01227055 ! protein targeting to vacuole GO:0006623 12 8 0,000 3,978E-03 0,01225484 ! protein retention in ER lumen GO:0006621 14 8 0,000 3,978E-03 0,01223917 ! intermediate filament organization GO:0045109 12 8 0,000 3,978E-03 0,01222353 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 3,978E-03 0,01220794 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 3,978E-03 0,01219239 ! cellular extravasation GO:0045123 12 8 0,000 3,978E-03 0,01217688 ! cardiac muscle cell development GO:0055013 13 8 0,000 3,978E-03 0,01216141 ! regulation of circadian rhythm GO:0042752 16 8 0,000 3,978E-03 0,01214597 ! response to antibiotic GO:0046677 11 8 0,000 3,978E-03 0,01213058 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 3,978E-03 0,01211523 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 3,978E-03 0,01209991 ! DNA topological change GO:0006265 12 8 0,000 3,978E-03 0,01208463 ! response to tropane GO:0014073 15 8 0,000 3,978E-03 0,01206939 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 3,978E-03 0,01205419 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 3,978E-03 0,01203903 ! melanosome transport GO:0032402 13 8 0,000 3,978E-03 0,0120239 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 3,978E-03 0,01200882 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 3,978E-03 0,01199377 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 3,978E-03 0,01197876 ! mast cell activation GO:0045576 14 8 0,000 3,978E-03 0,01196378 ! multicellular organismal aging GO:0010259 18 8 0,000 3,978E-03 0,01194885 ! dendrite morphogenesis GO:0048813 13 8 0,000 3,978E-03 0,01193395 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 3,978E-03 0,01191909 ! nucleosome disassembly GO:0006337 14 8 0,000 3,978E-03 0,01190426 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 3,978E-03 0,01188948 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 3,978E-03 0,01187472 ! leukocyte activation during immune response GO:0002366 13 8 0,000 3,978E-03 0,01186001 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 3,978E-03 0,01184533 ! establishment of chromosome localization GO:0051303 12 8 0,000 3,978E-03 0,01183069 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 3,978E-03 0,01181608 ! intracellular lipid transport GO:0032365 13 8 0,000 3,978E-03 0,01180151 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 3,978E-03 0,01178698 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 3,978E-03 0,01177248 ! regulation of macrophage activation GO:0043030 15 8 0,000 3,978E-03 0,01175802 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 3,978E-03 0,01174359 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 3,978E-03 0,0117292 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 3,978E-03 0,01171484 ! hormone catabolic process GO:0042447 17 8 0,000 3,978E-03 0,01170052 ! positive regulation of glucose import GO:0046326 8 8 0,000 3,978E-03 0,01168624 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 3,978E-03 0,01167199 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 3,978E-03 0,01165777 ! ATP catabolic process GO:0006200 11 8 0,000 3,978E-03 0,01164359 ! blastocyst growth GO:0001832 19 8 0,000 3,978E-03 0,01162944 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 3,978E-03 0,01161533 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 3,978E-03 0,01160125 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 3,978E-03 0,0115872 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 3,978E-03 0,01157319 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 3,978E-03 0,01155921 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 3,978E-03 0,01154527 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 3,978E-03 0,01153136 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 3,978E-03 0,01151748 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 3,978E-03 0,01150364 ! amino sugar catabolic process GO:0046348 10 8 0,000 3,978E-03 0,01148983 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 3,978E-03 0,01147605 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 3,978E-03 0,01146231 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 3,978E-03 0,0114486 ! behavioral response to nicotine GO:0035095 12 8 0,000 3,978E-03 0,01143492 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 3,978E-03 0,01142127 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 3,978E-03 0,01140766 ! NAD biosynthetic process GO:0009435 13 8 0,000 3,978E-03 0,01139408 ! regulation of developmental growth GO:0048638 15 9 0,000 4,474E-03 0,01280012 ! axon extension GO:0048675 15 9 0,000 4,474E-03 0,01278492 ! autophagic vacuole formation GO:0000045 15 9 0,000 4,474E-03 0,01276976 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 4,474E-03 0,01275463 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 4,474E-03 0,01273953 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 4,474E-03 0,01272447 ! pentose-phosphate shunt GO:0006098 16 9 0,000 4,474E-03 0,01270945 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 4,474E-03 0,01269446 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 4,474E-03 0,01267951 ! cell proliferation in forebrain GO:0021846 15 9 0,000 4,474E-03 0,01266459 ! phosphate transport GO:0006817 19 9 0,000 4,474E-03 0,01264971 ! reproductive behavior GO:0019098 19 9 0,000 4,474E-03 0,01263486 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 4,474E-03 0,01262005 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 4,474E-03 0,01260527 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 4,474E-03 0,01259053 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 4,474E-03 0,01257582 ! GTP metabolic process GO:0046039 9 9 0,000 4,474E-03 0,01256115 ! RNA methylation GO:0001510 15 9 0,000 4,474E-03 0,01254651 ! elastic fiber assembly GO:0048251 15 9 0,000 4,474E-03 0,0125319 ! induction of positive chemotaxis GO:0050930 15 9 0,000 4,474E-03 0,01251733 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 4,474E-03 0,01250279 ! artery development GO:0060840 24 9 0,000 4,474E-03 0,01248829 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 4,474E-03 0,01247382 ! regulation of glycolysis GO:0006110 21 9 0,000 4,474E-03 0,01245938 ! cerebral cortex cell migration GO:0021795 15 9 0,000 4,474E-03 0,01244498 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 4,474E-03 0,01243061 ! chemosensory behavior GO:0007635 20 9 0,000 4,474E-03 0,01241627 ! microtubule bundle formation GO:0001578 21 9 0,000 4,474E-03 0,01240196 ! middle ear morphogenesis GO:0042474 14 9 0,000 4,474E-03 0,01238769 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 4,474E-03 0,01237345 ! leukocyte degranulation GO:0043299 16 9 0,000 4,474E-03 0,01235925 ! bile acid and bile salt transport GO:0015721 13 9 0,000 4,474E-03 0,01234507 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 4,474E-03 0,01233093 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 4,474E-03 0,01231682 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 4,474E-03 0,01230275 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 4,474E-03 0,0122887 ! protein targeting to ER GO:0045047 22 9 0,000 4,474E-03 0,01227469 ! ceramide biosynthetic process GO:0046513 19 9 0,000 4,474E-03 0,01226071 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 4,474E-03 0,01224676 ! T cell selection GO:0045058 23 9 0,000 4,474E-03 0,01223285 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 4,474E-03 0,01221896 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 4,474E-03 0,01220511 ! phosphagen metabolic process GO:0006599 12 9 0,000 4,474E-03 0,01219128 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 4,474E-03 0,01217749 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 4,474E-03 0,01216373 ! regulation of type I interferon production GO:0032479 12 9 0,000 4,474E-03 0,01215001 ! mannose metabolic process GO:0006013 13 9 0,000 4,474E-03 0,01213631 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 4,474E-03 0,01212264 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 4,474E-03 0,012109 ! Rac protein signal transduction GO:0016601 17 9 0,000 4,474E-03 0,0120954 ! receptor clustering GO:0043113 18 9 0,000 4,474E-03 0,01208182 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 4,474E-03 0,01206828 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 4,474E-03 0,01205476 ! ruffle organization GO:0031529 15 9 0,000 4,474E-03 0,01204128 ! retinol metabolic process GO:0042572 18 9 0,000 4,474E-03 0,01202783 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 4,474E-03 0,0120144 ! behavioral fear response GO:0001662 22 9 0,000 4,474E-03 0,01200101 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 4,474E-03 0,01198764 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 4,474E-03 0,01197431 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 4,474E-03 0,01196101 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 4,474E-03 0,01194773 ! protein heterooligomerization GO:0051291 16 9 0,000 4,474E-03 0,01193448 ! oligodendrocyte development GO:0014003 10 9 0,000 4,474E-03 0,01192127 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 4,474E-03 0,01190808 ! segment specification GO:0007379 13 9 0,000 4,474E-03 0,01189492 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 4,474E-03 0,01188179 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 4,474E-03 0,01186869 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 4,474E-03 0,01185562 ! response to amine stimulus GO:0014075 13 9 0,000 4,474E-03 0,01184258 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 4,474E-03 0,01182957 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 4,474E-03 0,01181658 ! erythrocyte development GO:0048821 15 9 0,000 4,474E-03 0,01180362 ! gas homeostasis GO:0033483 16 9 0,000 4,474E-03 0,0117907 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 4,474E-03 0,01177779 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 4,474E-03 0,01176492 ! renal water homeostasis GO:0003091 14 9 0,000 4,474E-03 0,01175208 ! postreplication repair GO:0006301 22 9 0,000 4,474E-03 0,01173926 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 4,474E-03 0,01172648 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 4,474E-03 0,01171372 ! icosanoid secretion GO:0032309 15 9 0,000 4,474E-03 0,01170098 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 4,474E-03 0,01168828 ! cerebellum morphogenesis GO:0021587 14 9 0,000 4,474E-03 0,0116756 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 4,474E-03 0,01166295 ! regulation of cell division GO:0051302 15 9 0,000 4,474E-03 0,01165033 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 4,474E-03 0,01163773 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 4,474E-03 0,01162517 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 4,474E-03 0,01161263 ! sterol catabolic process GO:0016127 11 9 0,000 4,474E-03 0,01160011 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 4,474E-03 0,01158763 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 4,474E-03 0,01157517 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 4,474E-03 0,01156273 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 4,474E-03 0,01155033 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 4,474E-03 0,01153795 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 4,474E-03 0,01152559 ! musculoskeletal movement GO:0050881 14 9 0,000 4,474E-03 0,01151327 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 4,474E-03 0,01150097 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 4,474E-03 0,01148869 ! regulation of synaptogenesis GO:0051963 15 9 0,000 4,474E-03 0,01147644 ! purine base metabolic process GO:0006144 21 9 0,000 4,474E-03 0,01146422 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 4,474E-03 0,01145203 ! pigment granule transport GO:0051904 17 9 0,000 4,474E-03 0,01143986 ! regulation of fibrinolysis GO:0051917 16 9 0,000 4,474E-03 0,01142771 ! regulation of telomere maintenance GO:0032204 14 9 0,000 4,474E-03 0,01141559 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 4,474E-03 0,0114035 ! regulation of muscle adaptation GO:0043502 14 9 0,000 4,474E-03 0,01139143 ! regulation of amino acid transport GO:0051955 11 9 0,000 4,474E-03 0,01137939 ! mitochondrion localization GO:0051646 15 9 0,000 4,474E-03 0,01136738 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 4,97E-03 0,01261416 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 4,97E-03 0,01260087 ! negative regulation of blood pressure GO:0045776 26 10 0,000 4,97E-03 0,01258761 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 4,97E-03 0,01257437 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 4,97E-03 0,01256116 ! synapsis GO:0007129 13 10 0,000 4,97E-03 0,01254798 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 4,97E-03 0,01253483 ! N-glycan processing GO:0006491 20 10 0,000 4,97E-03 0,0125217 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 4,97E-03 0,0125086 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 4,97E-03 0,01249553 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 4,97E-03 0,01248249 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 4,97E-03 0,01246947 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 4,97E-03 0,01245649 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 4,97E-03 0,01244352 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 4,97E-03 0,01243059 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 4,97E-03 0,01241768 ! androgen metabolic process GO:0008209 17 10 0,000 4,97E-03 0,0124048 ! phospholipid efflux GO:0033700 16 10 0,000 4,97E-03 0,01239194 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 4,97E-03 0,01237912 ! positive regulation of heart contraction GO:0045823 16 10 0,000 4,97E-03 0,01236631 ! lung alveolus development GO:0048286 26 10 0,000 4,97E-03 0,01235354 ! pathogenesis GO:0009405 13 10 0,000 4,97E-03 0,01234079 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 4,97E-03 0,01232807 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 4,97E-03 0,01231537 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 4,97E-03 0,0123027 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 4,97E-03 0,01229006 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 4,97E-03 0,01227744 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 4,97E-03 0,01226485 ! arginine catabolic process GO:0006527 13 10 0,000 4,97E-03 0,01225228 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 4,97E-03 0,01223974 ! proline metabolic process GO:0006560 13 10 0,000 4,97E-03 0,01222723 ! glucan biosynthetic process GO:0009250 14 10 0,000 4,97E-03 0,01221474 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 4,97E-03 0,01220227 ! polyamine biosynthetic process GO:0006596 12 10 0,000 4,97E-03 0,01218983 ! V(D)J recombination GO:0033151 28 10 0,000 4,97E-03 0,01217742 ! reverse cholesterol transport GO:0043691 16 10 0,000 4,97E-03 0,01216503 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 4,97E-03 0,01215267 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 4,97E-03 0,01214033 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 4,97E-03 0,01212802 ! regulation of sodium ion transport GO:0002028 21 10 0,000 4,97E-03 0,01211573 ! multicellular organism growth GO:0035264 18 10 0,000 4,97E-03 0,01210347 ! phagocytosis, engulfment GO:0006911 28 10 0,000 4,97E-03 0,01209123 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 4,97E-03 0,01207902 ! epithelial cell development GO:0002064 20 10 0,000 4,97E-03 0,01206683 ! lens development in camera-type eye GO:0002088 16 10 0,000 4,97E-03 0,01205466 ! retinoic acid metabolic process GO:0042573 14 10 0,000 4,97E-03 0,01204252 ! macroautophagy GO:0016236 17 10 0,000 4,97E-03 0,01203041 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 4,97E-03 0,01201832 ! positive regulation of translational initiation GO:0045948 11 10 0,000 4,97E-03 0,01200625 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 4,97E-03 0,01199421 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 4,97E-03 0,01198219 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 4,97E-03 0,0119702 ! copper ion homeostasis GO:0055070 13 10 0,000 4,97E-03 0,01195823 ! regulation of bone resorption GO:0045124 25 10 0,000 4,97E-03 0,01194628 ! regulation of gliogenesis GO:0014013 23 10 0,000 4,97E-03 0,01193436 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 4,97E-03 0,01192246 ! alpha-beta T cell activation GO:0046631 23 10 0,000 4,97E-03 0,01191058 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 4,97E-03 0,01189873 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 4,97E-03 0,0118869 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 4,97E-03 0,0118751 ! blastoderm segmentation GO:0007350 18 10 0,000 4,97E-03 0,01186332 ! response to dsRNA GO:0043331 20 10 0,000 4,97E-03 0,01185156 ! DNA ligation GO:0006266 19 10 0,000 4,97E-03 0,01183983 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 4,97E-03 0,01182812 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 4,97E-03 0,01181643 ! melanosome localization GO:0032400 16 10 0,000 4,97E-03 0,01180476 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 4,97E-03 0,01179312 ! regulation of B cell differentiation GO:0045577 19 10 0,000 4,97E-03 0,0117815 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 4,97E-03 0,01176991 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 4,97E-03 0,01175833 ! mRNA cleavage GO:0006379 17 10 0,000 4,97E-03 0,01174678 ! protein sumoylation GO:0016925 15 10 0,000 4,97E-03 0,01173526 ! hindbrain morphogenesis GO:0021575 19 10 0,000 4,97E-03 0,01172375 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 4,97E-03 0,01171227 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 4,97E-03 0,01170081 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 4,97E-03 0,01168937 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 4,97E-03 0,01167796 ! salivary gland development GO:0007431 27 10 0,000 4,97E-03 0,01166656 ! prophase GO:0051324 15 10 0,000 4,97E-03 0,01165519 ! negative regulation of neurological system process GO:0031645 19 10 0,000 4,97E-03 0,01164384 ! apical protein localization GO:0045176 15 10 0,000 4,97E-03 0,01163252 ! ubiquinone metabolic process GO:0006743 15 10 0,000 4,97E-03 0,01162121 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 4,97E-03 0,01160993 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 4,97E-03 0,01159867 ! midbrain development GO:0030901 13 10 0,000 4,97E-03 0,01158743 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 4,97E-03 0,01157621 ! methionine biosynthetic process GO:0009086 19 10 0,000 4,97E-03 0,01156502 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 4,97E-03 0,01155384 ! quaternary ammonium group transport GO:0015697 21 10 0,000 4,97E-03 0,01154269 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 4,97E-03 0,01153156 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 4,97E-03 0,01152045 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 4,97E-03 0,01150936 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 4,97E-03 0,01149829 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 4,97E-03 0,01148725 ! oocyte development GO:0048599 17 10 0,000 4,97E-03 0,01147622 ! establishment of pigment granule localization GO:0051905 18 10 0,000 4,97E-03 0,01146522 ! blastocyst formation GO:0001825 17 10 0,000 4,97E-03 0,01145424 ! cerebellar cortex development GO:0021695 15 10 0,000 4,97E-03 0,01144328 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 4,97E-03 0,01143234 ! activation of innate immune response GO:0002218 12 10 0,000 4,97E-03 0,01142142 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 4,97E-03 0,01141052 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 4,97E-03 0,01139964 ! response to nicotine GO:0035094 20 10 0,000 4,97E-03 0,01138879 ! establishment of cell polarity GO:0030010 16 10 0,000 4,97E-03 0,01137795 ! negative regulation of immune effector process GO:0002698 20 10 0,000 4,97E-03 0,01136714 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 4,97E-03 0,01135634 ! localization within membrane GO:0051668 20 10 0,000 4,97E-03 0,01134557 ! negative regulation of muscle development GO:0048635 20 11 0,000 5,466E-03 0,0124654 ! respiratory burst GO:0045730 17 11 0,000 5,466E-03 0,01245359 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 5,466E-03 0,01244181 ! neuron fate specification GO:0048665 17 11 0,000 5,466E-03 0,01243005 ! telencephalon cell migration GO:0022029 20 11 0,000 5,466E-03 0,01241831 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 5,466E-03 0,0124066 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 5,466E-03 0,0123949 ! thyroid gland development GO:0030878 26 11 0,000 5,466E-03 0,01238323 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 5,466E-03 0,01237158 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 5,466E-03 0,01235996 ! Golgi vesicle budding GO:0048194 22 11 0,000 5,466E-03 0,01234835 ! response to pain GO:0048265 24 11 0,000 5,466E-03 0,01233677 ! detection of mechanical stimulus GO:0050982 22 11 0,000 5,466E-03 0,0123252 ! T cell proliferation GO:0042098 26 11 0,000 5,466E-03 0,01231366 ! blood vessel remodeling GO:0001974 29 11 0,000 5,466E-03 0,01230214 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 5,466E-03 0,01229065 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 5,466E-03 0,01227917 ! bone resorption GO:0045453 16 11 0,000 5,466E-03 0,01226772 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 5,466E-03 0,01225628 ! ventral spinal cord development GO:0021517 21 11 0,000 5,466E-03 0,01224487 ! negative regulation of proteolysis GO:0045861 25 11 0,000 5,466E-03 0,01223348 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 5,466E-03 0,01222211 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 5,466E-03 0,01221076 ! melanocyte differentiation GO:0030318 21 11 0,000 5,466E-03 0,01219944 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 5,466E-03 0,01218813 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 5,466E-03 0,01217685 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 5,466E-03 0,01216558 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 5,466E-03 0,01215434 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 5,466E-03 0,01214311 ! lipid digestion GO:0044241 18 11 0,000 5,466E-03 0,01213191 ! substrate-bound cell migration GO:0006929 13 11 0,000 5,466E-03 0,01212073 ! adult heart development GO:0007512 14 11 0,000 5,466E-03 0,01210957 ! chondrocyte differentiation GO:0002062 24 11 0,000 5,466E-03 0,01209843 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 5,466E-03 0,01208731 ! temperature homeostasis GO:0001659 17 11 0,000 5,466E-03 0,01207621 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 5,466E-03 0,01206513 ! negative regulation of ossification GO:0030279 26 11 0,000 5,466E-03 0,01205407 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 5,466E-03 0,01204303 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 5,466E-03 0,01203202 ! regulation of organ growth GO:0046620 13 11 0,000 5,466E-03 0,01202102 ! pigment granule localization GO:0051875 20 11 0,000 5,466E-03 0,01201004 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 5,466E-03 0,01199908 ! vasoconstriction GO:0042310 18 11 0,000 5,466E-03 0,01198814 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 5,466E-03 0,01197722 ! embryonic axis specification GO:0000578 18 11 0,000 5,466E-03 0,01196633 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 5,466E-03 0,01195545 ! snRNA metabolic process GO:0016073 24 11 0,000 5,466E-03 0,01194459 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 5,466E-03 0,01193375 ! nitric oxide metabolic process GO:0046209 15 11 0,000 5,466E-03 0,01192293 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 5,466E-03 0,01191213 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 5,466E-03 0,01190135 ! zymogen activation GO:0031638 15 11 0,000 5,466E-03 0,01189059 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 5,466E-03 0,01187985 ! neuroblast proliferation GO:0007405 24 11 0,000 5,466E-03 0,01186913 ! nucleosome positioning GO:0016584 15 11 0,000 5,466E-03 0,01185842 ! regulation of isotype switching GO:0045191 22 11 0,000 5,466E-03 0,01184774 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 5,466E-03 0,01183708 ! glutathione biosynthetic process GO:0006750 13 11 0,000 5,466E-03 0,01182643 ! regulation of leukocyte migration GO:0002685 26 11 0,000 5,466E-03 0,01181581 ! acid secretion GO:0046717 18 11 0,000 5,466E-03 0,0118052 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 5,466E-03 0,01179461 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 5,466E-03 0,01178404 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 5,466E-03 0,01177349 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 5,466E-03 0,01176296 ! oocyte differentiation GO:0009994 18 11 0,000 5,466E-03 0,01175245 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 5,466E-03 0,01174196 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 5,466E-03 0,01173148 ! cholesterol efflux GO:0033344 19 11 0,000 5,466E-03 0,01172103 ! anterior/posterior axis specification GO:0009948 18 11 0,000 5,466E-03 0,01171059 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 5,466E-03 0,01170017 ! negative regulation of glucose import GO:0046325 17 11 0,000 5,466E-03 0,01168977 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 5,466E-03 0,01167939 ! embryonic gut development GO:0048566 15 11 0,000 5,466E-03 0,01166903 ! regulation of organic acid transport GO:0032890 18 11 0,000 5,466E-03 0,01165868 ! cardiac cell differentiation GO:0035051 31 11 0,000 5,466E-03 0,01164836 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 5,466E-03 0,01163805 ! defense response to fungus GO:0050832 13 11 0,000 5,466E-03 0,01162776 ! developmental induction GO:0031128 19 11 0,000 5,466E-03 0,01161748 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 5,466E-03 0,01160723 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 5,466E-03 0,011597 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 5,466E-03 0,01158678 ! sequestering of metal ion GO:0051238 14 11 0,000 5,466E-03 0,01157658 ! lamellipodium assembly GO:0030032 20 11 0,000 5,466E-03 0,0115664 ! regulation of embryonic development GO:0045995 27 11 0,000 5,466E-03 0,01155623 ! nucleus localization GO:0051647 19 11 0,000 5,466E-03 0,01154609 ! regulation of synapse organization GO:0050807 17 11 0,000 5,466E-03 0,01153596 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 5,961E-03 0,01257073 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 5,961E-03 0,01255972 ! positive regulation of blood pressure GO:0045777 17 12 0,000 5,961E-03 0,01254874 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 5,961E-03 0,01253777 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 5,961E-03 0,01252682 ! virus-host interaction GO:0019048 29 12 0,000 5,961E-03 0,01251589 ! regulation of B cell proliferation GO:0030888 20 12 0,000 5,961E-03 0,01250497 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 5,961E-03 0,01249408 ! cartilage condensation GO:0001502 20 12 0,000 5,961E-03 0,01248321 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 5,961E-03 0,01247235 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 5,961E-03 0,01246152 ! protein complex disassembly GO:0043241 27 12 0,000 5,961E-03 0,0124507 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 5,961E-03 0,0124399 ! regulation of cell projection assembly GO:0060491 30 12 0,000 5,961E-03 0,01242912 ! hippocampus development GO:0021766 26 12 0,000 5,961E-03 0,01241836 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 5,961E-03 0,01240762 ! cytokine biosynthetic process GO:0042089 21 12 0,000 5,961E-03 0,01239689 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 5,961E-03 0,01238619 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 5,961E-03 0,0123755 ! regulation of exit from mitosis GO:0007096 17 12 0,000 5,961E-03 0,01236483 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 5,961E-03 0,01235418 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 5,961E-03 0,01234355 ! drug transport GO:0015893 16 12 0,000 5,961E-03 0,01233294 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 5,961E-03 0,01232234 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 5,961E-03 0,01231176 ! tyrosine metabolic process GO:0006570 16 12 0,000 5,961E-03 0,0123012 ! polyamine metabolic process GO:0006595 17 12 0,000 5,961E-03 0,01229066 ! focal adhesion formation GO:0048041 35 12 0,000 5,961E-03 0,01228014 ! mitotic spindle organization GO:0007052 21 12 0,000 5,961E-03 0,01226964 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 5,961E-03 0,01225915 ! forebrain cell migration GO:0021885 21 12 0,000 5,961E-03 0,01224868 ! asymmetric protein localization GO:0008105 20 12 0,000 5,961E-03 0,01223823 ! membrane protein proteolysis GO:0033619 25 12 0,000 5,961E-03 0,0122278 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 5,961E-03 0,01221738 ! entry into host cell GO:0030260 32 12 0,000 5,961E-03 0,01220698 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 5,961E-03 0,0121966 ! monoamine transport GO:0015844 18 12 0,000 5,961E-03 0,01218624 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 5,961E-03 0,0121759 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 5,961E-03 0,01216557 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 5,961E-03 0,01215526 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 5,961E-03 0,01214497 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 5,961E-03 0,01213469 ! protein targeting to peroxisome GO:0006625 23 12 0,000 5,961E-03 0,01212443 ! protein homotetramerization GO:0051289 21 12 0,000 5,961E-03 0,01211419 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 5,961E-03 0,01210397 ! regulation of phagocytosis GO:0050764 16 12 0,000 5,961E-03 0,01209376 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 5,961E-03 0,01208358 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 5,961E-03 0,0120734 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 5,961E-03 0,01206325 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 5,961E-03 0,01205311 ! cranial nerve development GO:0021545 20 12 0,000 5,961E-03 0,01204299 ! fucose catabolic process GO:0019317 22 12 0,000 5,961E-03 0,01203289 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 5,961E-03 0,0120228 ! histone acetylation GO:0016573 26 12 0,000 5,961E-03 0,01201273 ! histone methylation GO:0016571 26 12 0,000 5,961E-03 0,01200268 ! mRNA polyadenylation GO:0006378 23 12 0,000 5,961E-03 0,01199265 ! autonomic nervous system development GO:0048483 24 12 0,000 5,961E-03 0,01198263 ! gland morphogenesis GO:0022612 29 12 0,000 5,961E-03 0,01197263 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 5,961E-03 0,01196264 ! peptidyl-lysine modification GO:0018205 21 12 0,000 5,961E-03 0,01195267 ! T cell homeostasis GO:0043029 25 12 0,000 5,961E-03 0,01194272 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 5,961E-03 0,01193278 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 5,961E-03 0,01192286 ! spleen development GO:0048536 22 12 0,000 5,961E-03 0,01191296 ! biogenic amine catabolic process GO:0042402 23 12 0,000 5,961E-03 0,01190307 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 5,961E-03 0,0118932 ! regulation of RNA splicing GO:0043484 20 12 0,000 5,961E-03 0,01188335 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 5,961E-03 0,01187351 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 5,961E-03 0,01186369 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 5,961E-03 0,01185389 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 5,961E-03 0,0118441 ! response to cold GO:0009409 17 12 0,000 5,961E-03 0,01183433 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 5,961E-03 0,01182457 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 5,961E-03 0,01181483 ! cGMP metabolic process GO:0046068 18 13 0,000 6,457E-03 0,0127859 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 6,457E-03 0,01277538 ! regulation of chemokine production GO:0032642 18 13 0,000 6,457E-03 0,01276488 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 6,457E-03 0,0127544 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 6,457E-03 0,01274394 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 6,457E-03 0,01273349 ! lipid localization GO:0010876 28 13 0,000 6,457E-03 0,01272307 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 6,457E-03 0,01271265 ! organelle fusion GO:0048284 32 13 0,000 6,457E-03 0,01270226 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 6,457E-03 0,01269188 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 6,457E-03 0,01268152 ! pseudouridine synthesis GO:0001522 17 13 0,000 6,457E-03 0,01267118 ! endocrine pancreas development GO:0031018 22 13 0,000 6,457E-03 0,01266085 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 6,457E-03 0,01265054 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 6,457E-03 0,01264025 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 6,457E-03 0,01262997 ! methionine metabolic process GO:0006555 27 13 0,000 6,457E-03 0,01261971 ! plasma membrane organization GO:0007009 24 13 0,000 6,457E-03 0,01260947 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 6,457E-03 0,01259924 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 6,457E-03 0,01258903 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 6,457E-03 0,01257884 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 6,457E-03 0,01256866 ! cell-cell junction assembly GO:0007043 27 13 0,000 6,457E-03 0,0125585 ! response to X-ray GO:0010165 25 13 0,000 6,457E-03 0,01254835 ! cytokine metabolic process GO:0042107 22 13 0,000 6,457E-03 0,01253823 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 6,457E-03 0,01252811 ! exocrine system development GO:0035272 32 13 0,000 6,457E-03 0,01251802 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 6,457E-03 0,01250794 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 6,457E-03 0,01249788 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 6,457E-03 0,01248783 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 6,457E-03 0,0124778 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 6,457E-03 0,01246779 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 6,457E-03 0,01245779 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 6,457E-03 0,01244781 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 6,457E-03 0,01243784 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 6,457E-03 0,01242789 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 6,457E-03 0,01241796 ! regulation of cellular pH GO:0030641 22 13 0,000 6,457E-03 0,01240804 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 6,457E-03 0,01239813 ! ribosome assembly GO:0042255 17 13 0,000 6,457E-03 0,01238825 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 6,457E-03 0,01237838 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 6,457E-03 0,01236852 ! chromatin silencing GO:0006342 26 13 0,000 6,457E-03 0,01235868 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 6,457E-03 0,01234886 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 6,457E-03 0,01233905 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 6,457E-03 0,01232926 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 6,457E-03 0,01231948 ! regulation of mRNA stability GO:0043488 31 13 0,000 6,457E-03 0,01230972 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 6,457E-03 0,01229997 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 6,457E-03 0,01229024 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 6,457E-03 0,01228052 ! mRNA 3'-end processing GO:0031124 24 13 0,000 6,457E-03 0,01227082 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 6,457E-03 0,01226114 ! embryonic placenta development GO:0001892 23 13 0,000 6,457E-03 0,01225147 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 6,457E-03 0,01224181 ! insulin secretion GO:0030073 23 13 0,000 6,457E-03 0,01223218 ! actin filament polymerization GO:0030041 24 13 0,000 6,457E-03 0,01222255 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 6,457E-03 0,01221294 ! acrosome reaction GO:0007340 18 13 0,000 6,457E-03 0,01220335 ! rRNA transcription GO:0009303 25 14 0,000 6,952E-03 0,0131287 ! lactation GO:0007595 26 14 0,000 6,952E-03 0,0131184 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 6,952E-03 0,01310812 ! reproductive cellular process GO:0048610 20 14 0,000 6,952E-03 0,01309786 ! tRNA modification GO:0006400 20 14 0,000 6,952E-03 0,01308761 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 6,952E-03 0,01307738 ! regulation of S phase GO:0033261 23 14 0,000 6,952E-03 0,01306716 ! water transport GO:0006833 21 14 0,000 6,952E-03 0,01305696 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 6,952E-03 0,01304678 ! non-recombinational repair GO:0000726 25 14 0,000 6,952E-03 0,01303661 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 6,952E-03 0,01302645 ! retina development in camera-type eye GO:0060041 27 14 0,000 6,952E-03 0,01301632 ! RNA polyadenylation GO:0043631 30 14 0,000 6,952E-03 0,01300619 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 6,952E-03 0,01299609 ! palate development GO:0060021 31 14 0,000 6,952E-03 0,012986 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 6,952E-03 0,01297592 ! regulated secretory pathway GO:0045055 23 14 0,000 6,952E-03 0,01296587 ! regulation of mRNA processing GO:0050684 24 14 0,000 6,952E-03 0,01295582 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 6,952E-03 0,01294579 ! arginine metabolic process GO:0006525 17 14 0,000 6,952E-03 0,01293578 ! regulation of heart rate GO:0002027 24 14 0,000 6,952E-03 0,01292579 ! organic alcohol transport GO:0015850 29 14 0,000 6,952E-03 0,0129158 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 6,952E-03 0,01290584 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 6,952E-03 0,01289589 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 6,952E-03 0,01288595 ! neutral amino acid transport GO:0015804 26 14 0,000 6,952E-03 0,01287603 ! L-amino acid transport GO:0015807 30 14 0,000 6,952E-03 0,01286613 ! bone mineralization GO:0030282 17 14 0,000 6,952E-03 0,01285624 ! stem cell development GO:0048864 43 14 0,000 6,952E-03 0,01284636 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 6,952E-03 0,0128365 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 6,952E-03 0,01282666 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 6,952E-03 0,01281683 ! cerebellum development GO:0021549 21 14 0,000 6,952E-03 0,01280702 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 6,952E-03 0,01279722 ! negative regulation of protein secretion GO:0050709 28 14 0,000 6,952E-03 0,01278744 ! response to gamma radiation GO:0010332 28 14 0,000 6,952E-03 0,01277767 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 6,952E-03 0,01276791 ! cofactor transport GO:0051181 26 14 0,000 6,952E-03 0,01275817 ! NADP metabolic process GO:0006739 24 14 0,000 6,952E-03 0,01274845 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 6,952E-03 0,01273874 ! protein-chromophore linkage GO:0018298 19 14 0,000 6,952E-03 0,01272905 ! intestinal absorption GO:0050892 25 14 0,000 6,952E-03 0,01271937 ! cAMP biosynthetic process GO:0006171 23 14 0,000 6,952E-03 0,0127097 ! oxygen transport GO:0015671 21 14 0,000 6,952E-03 0,01270005 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 6,952E-03 0,01269041 ! male genitalia development GO:0030539 24 14 0,000 6,952E-03 0,01268079 ! regulation of RNA stability GO:0043487 32 14 0,000 6,952E-03 0,01267119 ! regulation of axon extension GO:0030516 37 14 0,000 6,952E-03 0,01266159 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 6,952E-03 0,01265202 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 7,447E-03 0,01354234 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 7,447E-03 0,01353211 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 7,447E-03 0,0135219 ! phospholipid catabolic process GO:0009395 22 15 0,000 7,447E-03 0,0135117 ! copper ion transport GO:0006825 20 15 0,000 7,447E-03 0,01350152 ! heterophilic cell adhesion GO:0007157 39 15 0,000 7,447E-03 0,01349135 ! cardiac muscle contraction GO:0060048 26 15 0,000 7,447E-03 0,0134812 ! sulfate transport GO:0008272 23 15 0,000 7,447E-03 0,01347106 ! response to cAMP GO:0051591 22 15 0,000 7,447E-03 0,01346094 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 7,447E-03 0,01345084 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 7,447E-03 0,01344075 ! ciliary or flagellar motility GO:0001539 20 15 0,000 7,447E-03 0,01343067 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 7,447E-03 0,01342061 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 7,447E-03 0,01341057 ! response to hexose stimulus GO:0009746 22 15 0,000 7,447E-03 0,01340054 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 7,447E-03 0,01339052 ! glycoprotein catabolic process GO:0006516 26 15 0,000 7,447E-03 0,01338052 ! pituitary gland development GO:0021983 29 15 0,000 7,447E-03 0,01337053 ! vesicle coating GO:0006901 33 15 0,000 7,447E-03 0,01336056 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 7,447E-03 0,01335061 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 7,447E-03 0,01334067 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 7,447E-03 0,01333074 ! regulation of exocytosis GO:0017157 22 15 0,000 7,447E-03 0,01332083 ! G1/S transition checkpoint GO:0031575 40 15 0,000 7,447E-03 0,01331093 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 7,447E-03 0,01330105 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 7,447E-03 0,01329118 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 7,447E-03 0,01328133 ! regulation of vasodilation GO:0042312 26 15 0,000 7,447E-03 0,01327149 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 7,447E-03 0,01326167 ! histone deacetylation GO:0016575 20 15 0,000 7,447E-03 0,01325186 ! mRNA splice site selection GO:0006376 38 15 0,000 7,447E-03 0,01324207 ! tissue regeneration GO:0042246 26 15 0,000 7,447E-03 0,01323229 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 7,447E-03 0,01322252 ! water homeostasis GO:0030104 27 15 0,000 7,447E-03 0,01321277 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 7,447E-03 0,01320303 ! muscle maintenance GO:0046716 26 15 0,000 7,447E-03 0,01319331 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 7,447E-03 0,0131836 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 7,447E-03 0,01317391 ! regulation of ATPase activity GO:0043462 21 15 0,000 7,447E-03 0,01316423 ! dopamine metabolic process GO:0042417 35 15 0,000 7,447E-03 0,01315456 ! heme biosynthetic process GO:0006783 29 15 0,000 7,447E-03 0,01314491 ! cell killing GO:0001906 29 15 0,000 7,447E-03 0,01313528 ! lymphocyte homeostasis GO:0002260 30 15 0,000 7,447E-03 0,01312565 ! detection of bacterium GO:0016045 18 15 0,000 7,447E-03 0,01311604 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 7,447E-03 0,01310645 ! L-fucose metabolic process GO:0042354 30 15 0,000 7,447E-03 0,01309687 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 7,447E-03 0,0130873 ! peptide hormone processing GO:0016486 23 15 0,000 7,447E-03 0,01307775 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 7,941E-03 0,01393619 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 7,941E-03 0,01392603 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 7,941E-03 0,01391589 ! dicarboxylic acid transport GO:0006835 38 16 0,000 7,941E-03 0,01390576 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 7,941E-03 0,01389564 ! bone remodeling GO:0046849 27 16 0,000 7,941E-03 0,01388555 ! filopodium assembly GO:0046847 32 16 0,000 7,941E-03 0,01387546 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 7,941E-03 0,01386539 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 7,941E-03 0,01385534 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 7,941E-03 0,0138453 ! positive regulation of ion transport GO:0043270 21 16 0,000 7,941E-03 0,01383527 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 7,941E-03 0,01382526 ! startle response GO:0001964 28 16 0,000 7,941E-03 0,01381526 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 7,941E-03 0,01380528 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 7,941E-03 0,01379531 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 7,941E-03 0,01378536 ! activation of MAPKK activity GO:0000186 35 16 0,000 7,941E-03 0,01377542 ! regulation of defense response to virus GO:0050688 27 16 0,000 7,941E-03 0,0137655 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 7,941E-03 0,01375559 ! protein polyubiquitination GO:0000209 34 16 0,000 7,941E-03 0,01374569 ! glutamate metabolic process GO:0006536 22 16 0,000 7,941E-03 0,01373581 ! complement activation, alternative pathway GO:0006957 18 16 0,000 7,941E-03 0,01372594 ! response to osmotic stress GO:0006970 25 16 0,000 7,941E-03 0,01371609 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 7,941E-03 0,01370625 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 7,941E-03 0,01369642 ! fructose metabolic process GO:0006000 25 16 0,000 7,941E-03 0,01368661 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 7,941E-03 0,01367682 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 7,941E-03 0,01366703 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 7,941E-03 0,01365726 ! negative regulation of immune response GO:0050777 35 16 0,000 7,941E-03 0,01364751 ! axon cargo transport GO:0008088 43 16 0,000 7,941E-03 0,01363777 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 7,941E-03 0,01362804 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 7,941E-03 0,01361833 ! DNA replication initiation GO:0006270 27 16 0,000 7,941E-03 0,01360863 ! neuron recognition GO:0008038 35 16 0,000 7,941E-03 0,01359894 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 7,941E-03 0,01358927 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 7,941E-03 0,01357961 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 7,941E-03 0,01356997 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 7,941E-03 0,01356033 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 7,941E-03 0,01355072 ! sphingolipid catabolic process GO:0030149 27 16 0,000 7,941E-03 0,01354111 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 7,941E-03 0,01353152 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 7,941E-03 0,01352195 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 7,941E-03 0,01351238 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 7,941E-03 0,01350283 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 7,941E-03 0,0134933 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 7,941E-03 0,01348378 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 7,941E-03 0,01347427 ! defense response to virus GO:0051607 37 16 0,000 7,941E-03 0,01346477 ! positive regulation of cell killing GO:0031343 32 17 0,000 8,436E-03 0,01429292 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 8,436E-03 0,01428287 ! metencephalon development GO:0022037 30 17 0,000 8,436E-03 0,01427282 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 8,436E-03 0,01426279 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 8,436E-03 0,01425278 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 8,436E-03 0,01424277 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 8,436E-03 0,01423279 ! signal complex assembly GO:0007172 41 17 0,000 8,436E-03 0,01422281 ! endothelial cell migration GO:0043542 28 17 0,000 8,436E-03 0,01421285 ! inositol metabolic process GO:0006020 28 17 0,000 8,436E-03 0,01420291 ! gene silencing by RNA GO:0031047 36 17 0,000 8,436E-03 0,01419297 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 8,436E-03 0,01418306 ! glial cell development GO:0021782 27 17 0,000 8,436E-03 0,01417315 ! limbic system development GO:0021761 36 17 0,000 8,436E-03 0,01416326 ! adult walking behavior GO:0007628 33 17 0,000 8,436E-03 0,01415338 ! heart looping GO:0001947 30 17 0,000 8,436E-03 0,01414352 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 8,436E-03 0,01413367 ! regulation of viral genome replication GO:0045069 28 17 0,000 8,436E-03 0,01412384 ! myoblast differentiation GO:0045445 45 17 0,000 8,436E-03 0,01411401 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 8,436E-03 0,01410421 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 8,436E-03 0,01409441 ! regulation of survival gene product expression GO:0045884 33 17 0,000 8,436E-03 0,01408463 ! cardiac muscle tissue development GO:0048738 31 17 0,000 8,436E-03 0,01407486 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 8,436E-03 0,01406511 ! glycine metabolic process GO:0006544 28 17 0,000 8,436E-03 0,01405537 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 8,436E-03 0,01404564 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 8,436E-03 0,01403593 ! NAD metabolic process GO:0019674 29 17 0,000 8,436E-03 0,01402623 ! membrane budding GO:0006900 37 17 0,000 8,436E-03 0,01401654 ! DNA integration GO:0015074 29 17 0,000 8,436E-03 0,01400687 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 8,436E-03 0,01399721 ! regulation of protein binding GO:0043393 33 17 0,000 8,436E-03 0,01398756 ! nucleobase metabolic process GO:0009112 37 17 0,000 8,436E-03 0,01397793 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 8,436E-03 0,01396831 ! DNA unwinding during replication GO:0006268 27 17 0,000 8,436E-03 0,0139587 ! genitalia development GO:0048806 30 17 0,000 8,436E-03 0,01394911 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 8,436E-03 0,01393953 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 8,436E-03 0,01392996 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 8,436E-03 0,01392041 ! neutrophil chemotaxis GO:0030593 27 17 0,000 8,436E-03 0,01391087 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 8,436E-03 0,01390134 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 8,436E-03 0,01389182 ! steroid catabolic process GO:0006706 31 17 0,000 8,436E-03 0,01388232 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 8,436E-03 0,01387283 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 8,436E-03 0,01386336 ! gas transport GO:0015669 25 17 0,000 8,436E-03 0,01385389 ! organic cation transport GO:0015695 31 17 0,000 8,436E-03 0,01384444 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 8,436E-03 0,01383501 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 8,436E-03 0,01382558 ! RNA 3'-end processing GO:0031123 34 17 0,000 8,436E-03 0,01381617 ! microspike assembly GO:0030035 36 17 0,000 8,436E-03 0,01380677 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 8,436E-03 0,01379739 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 8,436E-03 0,01378801 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 8,93E-03 0,01458577 ! neuron maturation GO:0042551 42 18 0,000 8,93E-03 0,01457588 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 8,93E-03 0,01456599 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 8,93E-03 0,01455613 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 8,93E-03 0,01454627 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 8,93E-03 0,01453643 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 8,93E-03 0,0145266 ! aminoglycan catabolic process GO:0006026 22 18 0,000 8,93E-03 0,01451679 ! memory GO:0007613 31 18 0,000 8,93E-03 0,01450698 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 8,93E-03 0,01449719 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 8,93E-03 0,01448742 ! patterning of blood vessels GO:0001569 39 18 0,000 8,93E-03 0,01447766 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 8,93E-03 0,01446791 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 8,93E-03 0,01445817 ! positive regulation of proteolysis GO:0045862 31 18 0,000 8,93E-03 0,01444845 ! glutamine metabolic process GO:0006541 29 18 0,000 8,93E-03 0,01443874 ! response to retinoic acid GO:0032526 26 18 0,000 8,93E-03 0,01442904 ! cell-substrate junction assembly GO:0007044 54 18 0,000 8,93E-03 0,01441936 ! response to fungus GO:0009620 21 18 0,000 8,93E-03 0,01440969 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 8,93E-03 0,01440003 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 8,93E-03 0,01439038 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 8,93E-03 0,01438075 ! long-chain fatty acid transport GO:0015909 31 18 0,000 8,93E-03 0,01437113 ! peptide biosynthetic process GO:0043043 24 18 0,000 8,93E-03 0,01436153 ! vitamin transport GO:0051180 27 18 0,000 8,93E-03 0,01435193 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 8,93E-03 0,01434235 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 8,93E-03 0,01433278 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 8,93E-03 0,01432323 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 8,93E-03 0,01431369 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 8,93E-03 0,01430416 ! aromatic compound catabolic process GO:0019439 27 18 0,000 8,93E-03 0,01429464 ! nerve development GO:0021675 28 18 0,000 8,93E-03 0,01428513 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 8,93E-03 0,01427564 ! protein secretion GO:0009306 39 19 0,000 9,424E-03 0,01505523 ! positive regulation of translation GO:0045727 30 19 0,000 9,424E-03 0,01504524 ! negative regulation of defense response GO:0031348 25 19 0,000 9,424E-03 0,01503526 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 9,424E-03 0,0150253 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 9,424E-03 0,01501535 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 9,424E-03 0,01500541 ! lipid phosphorylation GO:0046834 35 19 0,000 9,424E-03 0,01499549 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 9,424E-03 0,01498558 ! forelimb morphogenesis GO:0035136 32 19 0,000 9,424E-03 0,01497568 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 9,424E-03 0,01496579 ! bile acid metabolic process GO:0008206 29 19 0,000 9,424E-03 0,01495592 ! mitotic chromosome condensation GO:0007076 34 19 0,000 9,424E-03 0,01494606 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 9,424E-03 0,01493622 ! cerebral cortex development GO:0021987 36 19 0,000 9,424E-03 0,01492638 ! pigmentation during development GO:0048066 41 19 0,000 9,424E-03 0,01491656 ! response to vitamin A GO:0033189 27 19 0,000 9,424E-03 0,01490676 ! heme metabolic process GO:0042168 36 19 0,000 9,424E-03 0,01489696 ! actin filament bundle formation GO:0051017 42 19 0,000 9,424E-03 0,01488718 ! neuromuscular junction development GO:0007528 34 19 0,000 9,424E-03 0,01487741 ! response to lipopolysaccharide GO:0032496 30 19 0,000 9,424E-03 0,01486766 ! plasma membrane fusion GO:0045026 28 19 0,000 9,424E-03 0,01485792 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 9,424E-03 0,01484819 ! peptide cross-linking GO:0018149 37 19 0,000 9,424E-03 0,01483847 ! protein export from nucleus GO:0006611 36 19 0,000 9,424E-03 0,01482876 ! heart process GO:0003015 30 19 0,000 9,424E-03 0,01481907 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 9,424E-03 0,01480939 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 9,424E-03 0,01479972 ! visual learning GO:0008542 36 19 0,000 9,424E-03 0,01479007 ! cellular pigmentation GO:0033059 36 19 0,000 9,424E-03 0,01478043 ! G1 phase GO:0051318 40 19 0,000 9,424E-03 0,0147708 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 9,424E-03 0,01476118 ! cell-cell junction organization GO:0045216 35 19 0,000 9,424E-03 0,01475158 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 9,424E-03 0,01474199 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 9,424E-03 0,01473241 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 9,424E-03 0,01472284 ! proximal/distal pattern formation GO:0009954 32 19 0,000 9,424E-03 0,01471329 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 9,424E-03 0,01470375 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 9,424E-03 0,01469422 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 9,424E-03 0,0146847 ! cilium assembly GO:0042384 37 19 0,000 9,424E-03 0,0146752 ! peptide hormone secretion GO:0030072 31 19 0,000 9,424E-03 0,0146657 ! protein import into nucleus, docking GO:0000059 41 20 0,000 9,917E-03 0,01542402 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 9,917E-03 0,01541406 ! positive regulation of ossification GO:0045778 47 20 0,000 9,917E-03 0,01540411 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 9,917E-03 0,01539417 ! protein amino acid deacetylation GO:0006476 29 20 0,000 9,917E-03 0,01538424 ! protein amino acid acetylation GO:0006473 39 20 0,000 9,917E-03 0,01537433 ! cAMP metabolic process GO:0046058 36 20 0,000 9,917E-03 0,01536443 ! response to vitamin GO:0033273 31 20 0,000 9,917E-03 0,01535454 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 9,917E-03 0,01534467 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 9,917E-03 0,01533481 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 9,917E-03 0,01532496 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 9,917E-03 0,01531512 ! response to alkaloid GO:0043279 38 20 0,000 9,917E-03 0,0153053 ! retinoid metabolic process GO:0001523 32 20 0,000 9,917E-03 0,01529549 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 9,917E-03 0,01528569 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 9,917E-03 0,0152759 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 9,917E-03 0,01526613 ! DNA duplex unwinding GO:0032508 31 20 0,000 9,917E-03 0,01525637 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 9,917E-03 0,01524662 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 9,917E-03 0,01523688 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 9,917E-03 0,01522716 ! D-ribose metabolic process GO:0006014 29 20 0,000 9,917E-03 0,01521745 ! body fluid secretion GO:0007589 31 20 0,000 9,917E-03 0,01520775 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 9,917E-03 0,01519806 ! peptide secretion GO:0002790 35 20 0,000 9,917E-03 0,01518839 ! stem cell differentiation GO:0048863 53 20 0,000 9,917E-03 0,01517873 ! behavioral interaction between organisms GO:0051705 38 20 0,000 9,917E-03 0,01516908 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 9,917E-03 0,01515944 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 9,917E-03 0,01514982 ! sensory perception of pain GO:0019233 30 20 0,000 9,917E-03 0,0151402 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 9,917E-03 0,0151306 ! diencephalon development GO:0021536 34 20 0,000 9,917E-03 0,01512102 ! protein localization in mitochondrion GO:0070585 32 20 0,000 9,917E-03 0,01511144 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 9,917E-03 0,01510187 ! detection of chemical stimulus GO:0009593 37 20 0,000 9,917E-03 0,01509232 ! positive regulation of neurological system process GO:0031646 32 20 0,000 9,917E-03 0,01508278 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 9,917E-03 0,01507325 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 9,917E-03 0,01506374 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 9,917E-03 0,01505423 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 9,917E-03 0,01504474 ! regulation of glucose import GO:0046324 29 20 0,000 9,917E-03 0,01503526 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 9,917E-03 0,01502579 ! actin filament-based movement GO:0030048 43 20 0,000 9,917E-03 0,01501634 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 9,917E-03 0,01500689 ! negative regulation of T cell activation GO:0050868 40 20 0,000 9,917E-03 0,01499746 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 9,917E-03 0,01498804 ! negative regulation of coagulation GO:0050819 29 20 0,000 9,917E-03 0,01497863 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 9,917E-03 0,01496924 ! regulation of cell killing GO:0031341 42 21 0,000 0,01041072 0,0157042 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01041072 0,01569436 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01041072 0,01568453 ! hormone secretion GO:0046879 38 21 0,000 0,01041072 0,01567471 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01041072 0,01566491 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01041072 0,01565512 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01041072 0,01564534 ! axis specification GO:0009798 38 21 0,000 0,01041072 0,01563558 ! ovarian follicle development GO:0001541 35 21 0,000 0,01041072 0,01562582 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01041072 0,01561608 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01041072 0,01560635 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01041072 0,01559663 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01041072 0,01558693 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01041072 0,01557723 ! cell aging GO:0007569 44 21 0,000 0,01041072 0,01556755 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01041072 0,01555788 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01041072 0,01554823 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01041072 0,01553858 ! cytolysis GO:0019835 24 21 0,000 0,01041072 0,01552895 ! vasodilation GO:0042311 39 21 0,000 0,01041072 0,01551933 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01041072 0,01550972 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01041072 0,01550012 ! oogenesis GO:0048477 36 21 0,000 0,01041072 0,01549053 ! DNA modification GO:0006304 34 21 0,000 0,01041072 0,01548096 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01041072 0,0154714 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01041072 0,01546185 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01041072 0,01545231 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01041072 0,01544278 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01041072 0,01543327 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01041072 0,01542376 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01041072 0,01541427 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01041072 0,01540479 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01041072 0,01539532 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01041072 0,01538587 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01041072 0,01537642 ! collagen catabolic process GO:0030574 28 21 0,000 0,01041072 0,01536699 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01041072 0,01535757 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01090394 0,01607529 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01090394 0,01606544 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01090394 0,01605561 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01090394 0,01604579 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01090394 0,01603598 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01090394 0,01602619 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01090394 0,0160164 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01090394 0,01600663 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01090394 0,01599687 ! regeneration GO:0031099 41 22 0,000 0,01090394 0,01598712 ! keratinization GO:0031424 28 22 0,000 0,01090394 0,01597739 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01090394 0,01596766 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01090394 0,01595795 ! sensory perception of taste GO:0050909 28 22 0,000 0,01090394 0,01594825 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01090394 0,01593856 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01090394 0,01592888 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01090394 0,01591922 ! vacuolar transport GO:0007034 36 22 0,000 0,01090394 0,01590956 ! lysosome organization GO:0007040 41 22 0,000 0,01090394 0,01589992 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01090394 0,01589029 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01090394 0,01588067 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01090394 0,01587107 ! fucose metabolic process GO:0006004 39 22 0,000 0,01090394 0,01586147 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01090394 0,01585189 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01090394 0,01584231 ! ureteric bud development GO:0001657 43 22 0,000 0,01090394 0,01583275 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01090394 0,0158232 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01090394 0,01581367 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01090394 0,01580414 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01090394 0,01579462 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01090394 0,01578512 ! sarcomere organization GO:0045214 30 22 0,000 0,01090394 0,01577563 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,01090394 0,01576615 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01090394 0,01575668 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01090394 0,01574722 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01090394 0,01573778 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01090394 0,01572834 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01090394 0,01571892 ! protein stabilization GO:0050821 39 22 0,000 0,01090394 0,0157095 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01139692 0,01640993 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01139692 0,01640012 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01139692 0,01639032 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01139692 0,01638052 ! gluconeogenesis GO:0006094 33 23 0,000 0,01139692 0,01637074 ! viral genome replication GO:0019079 41 23 0,000 0,01139692 0,01636098 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01139692 0,01635122 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01139692 0,01634148 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01139692 0,01633174 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01139692 0,01632202 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01139692 0,01631231 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01139692 0,01630261 ! visual behavior GO:0007632 42 23 0,000 0,01139692 0,01629293 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01139692 0,01628325 ! response to ethanol GO:0045471 46 23 0,000 0,01139692 0,01627359 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01139692 0,01626394 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01139692 0,0162543 ! peroxisome organization GO:0007031 37 23 0,000 0,01139692 0,01624467 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01139692 0,01623505 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01139692 0,01622544 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01139692 0,01621585 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01139692 0,01620626 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01139692 0,01619669 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01139692 0,01618713 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01139692 0,01617758 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01139692 0,01616804 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01139692 0,01615851 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01139692 0,016149 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01139692 0,01613949 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01139692 0,01613 ! fatty acid transport GO:0015908 44 23 0,000 0,01139692 0,01612052 ! platelet activation GO:0030168 37 23 0,000 0,01139692 0,01611104 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01139692 0,01610158 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01139692 0,01609213 ! hormone transport GO:0009914 40 23 0,000 0,01139692 0,0160827 ! cell-cell recognition GO:0009988 25 23 0,000 0,01139692 0,01607327 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01139692 0,01606385 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01139692 0,01605445 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01139692 0,01604505 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01139692 0,01603567 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01139692 0,0160263 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01188968 0,01670945 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,01188968 0,01669969 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01188968 0,01668995 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01188968 0,01668022 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,01188968 0,0166705 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01188968 0,01666079 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01188968 0,01665109 ! vesicle docking GO:0048278 47 24 0,000 0,01188968 0,0166414 ! spinal cord development GO:0021510 47 24 0,000 0,01188968 0,01663173 ! vacuole organization GO:0007033 43 24 0,000 0,01188968 0,01662206 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01188968 0,01661241 ! digestive system process GO:0022600 39 24 0,000 0,01188968 0,01660277 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01188968 0,01659314 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01188968 0,01658352 ! regulation of behavior GO:0050795 43 24 0,000 0,01188968 0,01657391 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01188968 0,01656432 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01188968 0,01655473 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01188968 0,01654515 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01188968 0,01653559 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01188968 0,01652604 ! membrane depolarization GO:0051899 39 24 0,000 0,01188968 0,0165165 ! pallium development GO:0021543 49 24 0,000 0,01188968 0,01650697 ! pentose metabolic process GO:0019321 35 24 0,000 0,01188968 0,01649745 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01188968 0,01648794 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01188968 0,01647844 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01188968 0,01646895 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01188968 0,01645948 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01188968 0,01645001 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01188968 0,01644056 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01188968 0,01643112 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01188968 0,01642168 ! regulation of amine transport GO:0051952 40 24 0,000 0,01188968 0,01641226 ! protein tetramerization GO:0051262 52 24 0,000 0,01188968 0,01640285 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,01238221 0,01707255 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,01238221 0,01706277 ! myelination GO:0042552 45 25 0,000 0,01238221 0,017053 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,01238221 0,01704325 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,01238221 0,0170335 ! phototransduction GO:0007602 33 25 0,000 0,01238221 0,01702377 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,01238221 0,01701405 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,01238221 0,01700434 ! sperm motility GO:0030317 31 25 0,000 0,01238221 0,01699464 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,01238221 0,01698495 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,01238221 0,01697527 ! receptor metabolic process GO:0043112 46 25 0,000 0,01238221 0,0169656 ! chromosome condensation GO:0030261 45 25 0,000 0,01238221 0,01695595 ! response to starvation GO:0042594 42 25 0,000 0,01238221 0,0169463 ! osteoblast differentiation GO:0001649 60 25 0,000 0,01238221 0,01693667 ! neural crest cell development GO:0014032 54 25 0,000 0,01238221 0,01692704 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,01238221 0,01691743 ! negative regulation of cell development GO:0010721 73 25 0,000 0,01238221 0,01690783 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,01238221 0,01689824 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,01238221 0,01688866 ! interaction with host GO:0051701 62 25 0,000 0,01238221 0,01687909 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,01238221 0,01686953 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,01238221 0,01685999 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,01238221 0,01685045 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,01238221 0,01684092 ! immunoglobulin production GO:0002377 55 25 0,000 0,01238221 0,01683141 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,01238221 0,01682191 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,01238221 0,01681241 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,01238221 0,01680293 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,01238221 0,01679346 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,01238221 0,016784 ! telomere organization GO:0032200 43 25 0,000 0,01238221 0,01677455 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,01238221 0,01676511 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,01238221 0,01675568 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,01287451 0,01741207 ! embryonic pattern specification GO:0009880 44 26 0,000 0,01287451 0,01740229 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,01287451 0,01739251 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,01287451 0,01738275 ! initiation of viral infection GO:0019059 57 26 0,000 0,01287451 0,017373 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,01287451 0,01736327 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,01287451 0,01735354 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,01287451 0,01734382 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,01287451 0,01733412 ! tube lumen formation GO:0035148 50 26 0,000 0,01287451 0,01732442 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,01287451 0,01731474 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,01287451 0,01730507 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,01287451 0,0172954 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,01287451 0,01728575 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,01287451 0,01727611 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,01287451 0,01726648 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,01287451 0,01725686 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,01287451 0,01724725 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,01287451 0,01723766 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,01287451 0,01722807 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,01287451 0,01721849 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,01287451 0,01720893 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,01287451 0,01719937 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,01287451 0,01718983 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,01287451 0,01718029 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,01287451 0,01717077 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,01287451 0,01716126 ! blastocyst development GO:0001824 49 26 0,000 0,01287451 0,01715175 ! leukocyte proliferation GO:0070661 52 26 0,000 0,01287451 0,01714226 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,01287451 0,01713278 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,01287451 0,01712331 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,01336658 0,01776795 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,01336658 0,01775814 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,01336658 0,01774834 ! iron ion transport GO:0006826 59 27 0,000 0,01336658 0,01773855 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,01336658 0,01772877 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,01336658 0,017719 ! protein amino acid acylation GO:0043543 55 27 0,000 0,01336658 0,01770924 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,01336658 0,0176995 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,01336658 0,01768976 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,01336658 0,01768004 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,01336658 0,01767032 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,01336658 0,01766062 ! autophagy GO:0006914 41 27 0,000 0,01336658 0,01765093 ! male gonad development GO:0008584 44 27 0,000 0,01336658 0,01764124 ! response to toxin GO:0009636 47 27 0,000 0,01336658 0,01763157 ! primary neural tube formation GO:0014020 51 27 0,000 0,01336658 0,01762191 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,01336658 0,01761226 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,01336658 0,01760262 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,01336658 0,01759299 ! glutathione metabolic process GO:0006749 39 27 0,000 0,01336658 0,01758337 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,01336658 0,01757376 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,01336658 0,01756417 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,01336658 0,01755458 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,01385842 0,01819059 ! circadian rhythm GO:0007623 50 28 0,000 0,01385842 0,01818068 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,01385842 0,01817077 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,01385842 0,01816087 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,01385842 0,01815098 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,01385842 0,01814111 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,01385842 0,01813124 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,01385842 0,01812139 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,01385842 0,01811155 ! synaptogenesis GO:0007416 42 28 0,000 0,01385842 0,01810171 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,01385842 0,01809189 ! lipid oxidation GO:0034440 43 28 0,000 0,01385842 0,01808208 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,01385842 0,01807228 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,01385842 0,01806249 ! translational initiation GO:0006413 65 29 0,000 0,01435003 0,01869311 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,01435003 0,018683 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,01435003 0,01867289 ! regulation of pH GO:0006885 43 29 0,000 0,01435003 0,0186628 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,01435003 0,01865272 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,01435003 0,01864264 ! catechol metabolic process GO:0009712 54 29 0,000 0,01435003 0,01863258 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,01435003 0,01862253 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,01435003 0,01861249 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,01435003 0,01860247 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,01435003 0,01859245 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,01435003 0,01858244 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,01435003 0,01857245 ! cell fate determination GO:0001709 60 29 0,000 0,01435003 0,01856246 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,01435003 0,01855249 ! detection of light stimulus GO:0009583 38 29 0,000 0,01435003 0,01854252 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,01435003 0,01853257 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,01435003 0,01852263 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,01435003 0,0185127 ! tissue homeostasis GO:0001894 48 29 0,000 0,01435003 0,01850277 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,01435003 0,01849286 ! phenol metabolic process GO:0018958 55 30 0,000 0,01484142 0,01911587 ! zinc ion transport GO:0006829 45 30 0,000 0,01484142 0,01910564 ! membrane docking GO:0022406 61 30 0,000 0,01484142 0,01909543 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,01484142 0,01908522 ! cell junction assembly GO:0034329 78 30 0,000 0,01484142 0,01907502 ! regulation of innate immune response GO:0045088 51 30 0,000 0,01484142 0,01906484 ! acute-phase response GO:0006953 49 30 0,000 0,01484142 0,01905467 ! myofibril assembly GO:0030239 47 30 0,000 0,01484142 0,0190445 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,01484142 0,01903435 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,01484142 0,01902421 ! phospholipid transport GO:0015914 51 30 0,000 0,01484142 0,01901408 ! ensheathment of neurons GO:0007272 57 30 0,000 0,01484142 0,01900396 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,01484142 0,01899385 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,01484142 0,01898376 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,01484142 0,01897367 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,01484142 0,01896359 ! eye morphogenesis GO:0048592 60 30 0,000 0,01484142 0,01895353 ! regulation of B cell activation GO:0050864 50 30 0,000 0,01484142 0,01894347 ! response to heat GO:0009408 50 30 0,000 0,01484142 0,01893343 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,01533257 0,01954964 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,01533257 0,01953928 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,01533257 0,01952894 ! collagen metabolic process GO:0032963 45 31 0,000 0,01533257 0,01951861 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,01533257 0,01950828 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,01533257 0,01949797 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,01533257 0,01948767 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,01533257 0,01947738 ! ovulation cycle process GO:0022602 49 31 0,000 0,01533257 0,01946711 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,01533257 0,01945684 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,01533257 0,01944658 ! peptide transport GO:0015833 55 31 0,000 0,01533257 0,01943634 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,01533257 0,0194261 ! iron ion homeostasis GO:0055072 54 31 0,000 0,01533257 0,01941588 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,01533257 0,01940566 ! mesoderm formation GO:0001707 69 31 0,000 0,01533257 0,01939546 ! natural killer cell activation GO:0030101 45 31 0,000 0,01533257 0,01938527 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,01533257 0,01937509 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,01533257 0,01936492 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,01533257 0,01935476 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,01533257 0,01934461 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,01533257 0,01933447 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0158235 0,01994308 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0158235 0,01993264 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0158235 0,01992221 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0158235 0,01991179 ! cholesterol transport GO:0030301 56 32 0,000 0,0158235 0,01990138 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0158235 0,01989098 ! spliceosome assembly GO:0000245 67 32 0,000 0,0158235 0,01988059 ! spindle organization GO:0007051 46 32 0,000 0,0158235 0,01987022 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0158235 0,01985985 ! metanephros development GO:0001656 74 32 0,000 0,0158235 0,0198495 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0158235 0,01983915 ! response to ionizing radiation GO:0010212 65 32 0,000 0,0158235 0,01982882 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0158235 0,0198185 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0158235 0,01980819 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,0158235 0,01979789 ! muscle cell development GO:0055001 49 32 0,000 0,0158235 0,0197876 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0158235 0,01977732 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0158235 0,01976705 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0158235 0,01975679 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,0158235 0,01974654 ! ovulation cycle GO:0042698 51 32 0,000 0,0158235 0,01973631 ! peripheral nervous system development GO:0007422 64 32 0,000 0,0158235 0,01972608 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0158235 0,01971586 ! hindbrain development GO:0030902 61 32 0,000 0,0158235 0,01970566 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0158235 0,01969547 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0158235 0,01968528 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,0158235 0,01967511 ! gene silencing GO:0016458 65 32 0,000 0,0158235 0,01966495 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,01631419 0,0202643 ! post-embryonic development GO:0009791 69 33 0,000 0,01631419 0,02025385 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,01631419 0,0202434 ! protein targeting to membrane GO:0006612 68 33 0,000 0,01631419 0,02023297 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,01631419 0,02022254 ! ceramide metabolic process GO:0006672 64 33 0,000 0,01631419 0,02021213 ! formation of primary germ layer GO:0001704 72 33 0,000 0,01631419 0,02020173 ! sterol transport GO:0015918 57 33 0,000 0,01631419 0,02019133 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,01631419 0,02018095 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,01631419 0,02017058 ! adult locomotory behavior GO:0008344 59 33 0,000 0,01631419 0,02016022 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,01631419 0,02014987 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,01631419 0,02013953 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,01680466 0,02073437 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,01680466 0,02072374 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,01680466 0,02071313 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,01680466 0,02070252 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,01680466 0,02069193 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,01680466 0,02068134 ! mismatch repair GO:0006298 46 34 0,000 0,01680466 0,02067077 ! spermatid development GO:0007286 63 34 0,000 0,01680466 0,02066021 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,01680466 0,02064965 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,01680466 0,02063911 ! placenta development GO:0001890 53 34 0,000 0,01680466 0,02062858 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,01680466 0,02061806 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,01729491 0,02120874 ! negative regulation of secretion GO:0051048 63 35 0,000 0,01729491 0,02119793 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,01729491 0,02118714 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,01729491 0,02117636 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,01729491 0,02116559 ! odontogenesis GO:0042476 66 35 0,000 0,01729491 0,02115483 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,01729491 0,02114408 ! female gonad development GO:0008585 58 35 0,000 0,01729491 0,02113334 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,01729491 0,02112261 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,01729491 0,02111189 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,01729491 0,02110119 ! cytokine production GO:0001816 59 35 0,000 0,01729491 0,02109049 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,01729491 0,02107981 ! neural tube formation GO:0001841 67 35 0,000 0,01729491 0,02106914 ! vesicle localization GO:0051648 64 35 0,000 0,01729491 0,02105847 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,01778492 0,02164417 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,01778492 0,02163322 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,01778492 0,02162229 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,01778492 0,02161137 ! cell junction organization GO:0034330 86 36 0,000 0,01778492 0,02160046 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,01778492 0,02158956 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,01778492 0,02157868 ! positive regulation of cell development GO:0010720 80 36 0,000 0,01778492 0,0215678 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,01778492 0,02155693 ! regulation of proteolysis GO:0030162 72 36 0,000 0,01778492 0,02154608 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,01778492 0,02153524 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,01778492 0,0215244 ! aerobic respiration GO:0009060 55 36 0,000 0,01778492 0,02151358 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,01778492 0,02150277 ! embryonic organ development GO:0048568 57 36 0,000 0,01778492 0,02149197 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,01778492 0,02148118 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,01778492 0,0214704 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,0182747 0,02205062 ! meiosis I GO:0007127 65 37 0,000 0,0182747 0,02203957 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,0182747 0,02202853 ! sister chromatid segregation GO:0000819 58 37 0,000 0,0182747 0,0220175 ! actomyosin structure organization GO:0031032 62 37 0,000 0,0182747 0,02200648 ! organic anion transport GO:0015711 68 37 0,000 0,0182747 0,02199547 ! tissue remodeling GO:0048771 76 37 0,000 0,0182747 0,02198447 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,0182747 0,02197348 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,0182747 0,02196251 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,0182747 0,02195154 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,0182747 0,02194059 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,0182747 0,02192965 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,0182747 0,02191871 ! pigment metabolic process GO:0042440 80 37 0,000 0,0182747 0,02190779 ! spermatid differentiation GO:0048515 66 37 0,000 0,0182747 0,02189688 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,0182747 0,02188598 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,01876426 0,0224611 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,01876426 0,02244993 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,01876426 0,02243877 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,01876426 0,02242763 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,01876426 0,02241649 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,01876426 0,02240537 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,01876426 0,02239425 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,01876426 0,02238315 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,01876426 0,02237206 ! lipid homeostasis GO:0055088 67 38 0,000 0,01876426 0,02236098 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,01876426 0,02234991 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,01876426 0,02233885 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,01876426 0,0223278 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,01876426 0,02231676 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,01876426 0,02230574 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,01876426 0,02229472 ! mRNA catabolic process GO:0006402 71 39 0,000 0,01925359 0,02286483 ! mammary gland development GO:0030879 86 39 0,000 0,01925359 0,02285355 ! learning GO:0007612 77 39 0,000 0,01925359 0,02284228 ! ear morphogenesis GO:0042471 60 39 0,000 0,01925359 0,02283102 ! organic ether metabolic process GO:0018904 55 39 0,000 0,01925359 0,02281977 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,01925359 0,02280854 ! segmentation GO:0035282 67 39 0,000 0,01925359 0,02279731 ! ion transmembrane transport GO:0034220 66 39 0,000 0,01925359 0,0227861 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,01925359 0,0227749 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,01925359 0,0227637 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,01925359 0,02275252 ! RNA modification GO:0009451 57 39 0,000 0,01925359 0,02274135 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,01925359 0,0227302 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,01974269 0,02329618 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,01974269 0,02328476 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,01974269 0,02327335 ! feeding behavior GO:0007631 59 40 0,000 0,01974269 0,02326196 ! negative regulation of binding GO:0051100 72 40 0,000 0,01974269 0,02325057 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,01974269 0,0232392 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,01974269 0,02322783 ! maintenance of protein location GO:0045185 91 40 0,000 0,01974269 0,02321648 ! cytokinesis GO:0000910 72 40 0,000 0,01974269 0,02320514 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,02023157 0,02376814 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,02023157 0,02375654 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,02023157 0,02374495 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,02023157 0,02373337 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,02023157 0,02372181 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,02023157 0,02371025 ! T cell differentiation GO:0030217 81 41 0,000 0,02023157 0,02369871 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,02023157 0,02368718 ! female gamete generation GO:0007292 61 41 0,000 0,02023157 0,02367566 ! polyol metabolic process GO:0019751 66 41 0,000 0,02023157 0,02366415 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,02023157 0,02365265 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,02072021 0,02421216 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,02072021 0,0242004 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,02072021 0,02418866 ! regulation of tube size GO:0035150 71 42 0,000 0,02072021 0,02417693 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,02072021 0,02416521 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,02072021 0,0241535 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,02072021 0,02414181 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,02072021 0,02413012 ! neuron migration GO:0001764 79 42 0,000 0,02072021 0,02411845 ! regulation of protein secretion GO:0050708 71 42 0,000 0,02072021 0,02410678 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,02072021 0,02409513 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,02120863 0,02465119 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,02120863 0,02463929 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,02120863 0,0246274 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,02120863 0,02461552 ! glucose transport GO:0015758 65 43 0,000 0,02120863 0,02460365 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,02120863 0,02459179 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,02120863 0,02457995 ! neural tube development GO:0021915 77 43 0,000 0,02120863 0,02456811 ! striated muscle contraction GO:0006941 77 43 0,000 0,02120863 0,02455629 ! phagocytosis GO:0006909 90 43 0,000 0,02120863 0,02454448 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,02120863 0,02453268 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,02169682 0,02508532 ! hexose transport GO:0008645 67 44 0,000 0,02169682 0,02507327 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,02169682 0,02506124 ! male sex differentiation GO:0046661 76 44 0,000 0,02169682 0,02504921 ! biopolymer methylation GO:0043414 84 44 0,000 0,02169682 0,0250372 ! B cell differentiation GO:0030183 107 44 0,000 0,02169682 0,02502519 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,02169682 0,0250132 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,02169682 0,02500122 ! maintenance of location in cell GO:0051651 97 44 0,000 0,02169682 0,02498926 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,02218479 0,02553904 ! glycolysis GO:0006096 65 45 0,000 0,02218479 0,02552683 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,02218479 0,02551463 ! leukocyte migration GO:0050900 68 45 0,000 0,02218479 0,02550244 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,02218479 0,02549026 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,02218479 0,02547809 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,02218479 0,02546593 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,02218479 0,02545379 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,02218479 0,02544166 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,02218479 0,02542954 ! cell growth GO:0016049 84 45 0,000 0,02218479 0,02541743 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,02267252 0,02596387 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,02267252 0,02595152 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,02267252 0,02593918 ! pigmentation GO:0043473 100 46 0,000 0,02267252 0,02592685 ! positive regulation of defense response GO:0031349 76 47 0,000 0,02316003 0,02647175 ! endosome transport GO:0016197 108 47 0,000 0,02316003 0,02645918 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,02316003 0,02644663 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,02316003 0,02643408 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,02316003 0,02642155 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,02316003 0,02640902 ! JNK cascade GO:0007254 91 47 0,000 0,02316003 0,02639651 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,02316003 0,02638402 ! methylation GO:0032259 90 47 0,000 0,02316003 0,02637153 ! protein homooligomerization GO:0051260 76 47 0,000 0,02316003 0,02635905 ! mitochondrial transport GO:0006839 82 48 0,000 0,02364732 0,02690092 ! cellular component disassembly GO:0022411 86 48 0,000 0,02364732 0,02688821 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,02364732 0,02687551 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,02364732 0,02686282 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,02364732 0,02685014 ! activation of caspase activity GO:0006919 84 48 0,000 0,02364732 0,02683747 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,02364732 0,02682482 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,02364732 0,02681218 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,02364732 0,02679955 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,02364732 0,02678693 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,02413437 0,02732579 ! regulation of action potential GO:0001508 95 49 0,000 0,02413437 0,02731294 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,02413437 0,02730009 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,02413437 0,02728727 ! regulation of ion transport GO:0043269 77 49 0,000 0,02413437 0,02727445 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,02413437 0,02726164 ! peptide metabolic process GO:0006518 76 49 0,000 0,02413437 0,02724885 ! response to temperature stimulus GO:0009266 76 49 0,000 0,02413437 0,02723607 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,02413437 0,0272233 ! endocrine system development GO:0035270 104 49 0,000 0,02413437 0,02721054 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,02413437 0,0271978 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,02413437 0,02718507 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,02413437 0,02717235 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,02413437 0,02715964 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,0246212 0,02769454 ! neuromuscular process GO:0050905 99 50 0,000 0,0246212 0,02768159 ! regulation of ossification GO:0030278 117 50 0,000 0,0246212 0,02766867 ! inner ear development GO:0048839 79 50 0,000 0,0246212 0,02765575 ! histone modification GO:0016570 91 50 0,000 0,0246212 0,02764284 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,0246212 0,02762995 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,0246212 0,02761707 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,0246212 0,0276042 ! positive regulation of binding GO:0051099 78 51 0,000 0,02510781 0,02813665 ! viral infectious cycle GO:0019058 99 51 0,000 0,02510781 0,02812355 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,02510781 0,02811046 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,02510781 0,02809739 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,02510781 0,02808432 ! excretion GO:0007588 83 51 0,000 0,02510781 0,02807127 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,02510781 0,02805823 ! chromatin remodeling GO:0006338 109 51 0,000 0,02510781 0,02804521 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,02510781 0,02803219 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,02510781 0,02801919 ! vesicle organization GO:0016050 107 51 0,000 0,02510781 0,0280062 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,02510781 0,02799322 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,02510781 0,02798026 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,02510781 0,02796731 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,02559418 0,02849588 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,02559418 0,0284827 ! membrane fusion GO:0006944 110 52 0,000 0,02559418 0,02846953 ! covalent chromatin modification GO:0016569 101 52 0,000 0,02559418 0,02845638 ! amino acid activation GO:0043038 92 52 0,000 0,02559418 0,02844323 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,02559418 0,0284301 ! synapse organization GO:0050808 85 52 0,000 0,02559418 0,02841698 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,02608033 0,02894339 ! RNA catabolic process GO:0006401 93 53 0,000 0,02608033 0,02893005 ! regulation of translational initiation GO:0006446 82 53 0,000 0,02608033 0,02891672 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,02608033 0,0289034 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,02608033 0,02889009 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,02608033 0,0288768 ! cell maturation GO:0048469 100 53 0,000 0,02608033 0,02886351 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,02608033 0,02885024 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,02608033 0,02883698 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,02656625 0,02936077 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,02656625 0,02934729 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,02656625 0,02933383 ! cell recognition GO:0008037 85 54 0,000 0,02656625 0,02932037 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,02656625 0,02930693 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,02656625 0,0292935 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,02656625 0,02928008 ! chloride transport GO:0006821 90 55 0,000 0,02705195 0,02980174 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,02705195 0,0297881 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,02705195 0,02977447 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,02705195 0,02976086 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,02705195 0,02974725 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,02705195 0,02973367 ! aging GO:0007568 103 55 0,000 0,02705195 0,02972009 ! gastrulation GO:0007369 112 55 0,000 0,02705195 0,02970652 ! heart morphogenesis GO:0003007 97 55 0,000 0,02705195 0,02969297 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,02705195 0,02967943 ! RNA elongation GO:0006354 79 55 0,000 0,02705195 0,0296659 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,02705195 0,02965239 ! regulation of actin filament length GO:0030832 105 56 0,000 0,02753742 0,03017078 ! sensory perception of smell GO:0007608 80 56 0,000 0,02753742 0,03015705 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,02753742 0,03014333 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,02753742 0,03012962 ! proton transport GO:0015992 94 56 0,000 0,02753742 0,03011593 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,02753742 0,03010224 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,02802267 0,03061877 ! muscle fiber development GO:0048747 112 57 0,000 0,02802267 0,03060487 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,02802267 0,03059099 ! lipid modification GO:0030258 97 57 0,000 0,02802267 0,03057711 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,02802267 0,03056325 ! maintenance of location GO:0051235 118 57 0,000 0,02802267 0,0305494 ! hydrogen transport GO:0006818 97 58 0,000 0,02850768 0,03106408 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,02850768 0,03105002 ! regulation of endocytosis GO:0030100 91 58 0,000 0,02850768 0,03103597 ! adult behavior GO:0030534 99 58 0,000 0,02850768 0,03102193 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,02850768 0,03100791 ! positive regulation of secretion GO:0051047 95 59 0,000 0,02899248 0,03152097 ! regulation of cellular component size GO:0032535 109 59 0,000 0,02899248 0,03150673 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,02899248 0,03149251 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,02899248 0,03147829 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,02899248 0,0314641 ! DNA catabolic process GO:0006308 86 59 0,000 0,02899248 0,03144991 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,02899248 0,03143574 ! establishment of organelle localization GO:0051656 109 59 0,000 0,02899248 0,03142158 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,02947704 0,03193236 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,02947704 0,03191799 ! regulation of heart contraction GO:0008016 110 60 0,000 0,02947704 0,03190363 ! camera-type eye development GO:0043010 116 60 0,000 0,02947704 0,03188928 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,02947704 0,03187495 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,02947704 0,03186063 ! kidney development GO:0001822 122 60 0,000 0,02947704 0,03184633 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,02996139 0,03235507 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,02996139 0,03234055 ! mesoderm development GO:0007498 119 61 0,000 0,02996139 0,03232605 ! tRNA processing GO:0008033 89 61 0,000 0,02996139 0,03231156 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,02996139 0,03229709 ! ear development GO:0043583 103 62 0,000 0,0304455 0,03280424 ! viral reproductive process GO:0022415 126 62 0,000 0,0304455 0,03278956 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,0304455 0,03277489 ! gonad development GO:0008406 98 62 0,000 0,0304455 0,03276023 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,0304455 0,03274559 ! regulation of mitosis GO:0007088 105 63 0,000 0,03092939 0,03325117 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,03092939 0,03323632 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,03092939 0,03322148 ! detection of external stimulus GO:0009581 91 63 0,000 0,03092939 0,03320666 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,03092939 0,03319184 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,03092939 0,03317705 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,03141306 0,03368084 ! cell redox homeostasis GO:0045454 102 64 0,000 0,03141306 0,03366584 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,03141306 0,03365085 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,03141306 0,03363588 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,03141306 0,03362091 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,03141306 0,03360596 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0318965 0,03410799 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0318965 0,03409283 ! germ cell development GO:0007281 118 65 0,000 0,0318965 0,03407769 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,0318965 0,03406257 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,03237971 0,03456326 ! actin filament organization GO:0007015 148 66 0,000 0,03237971 0,03454793 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,03237971 0,03453262 ! extracellular matrix organization GO:0030198 133 66 0,000 0,03237971 0,03451732 ! secondary metabolic process GO:0019748 116 66 0,000 0,03237971 0,03450203 ! cell projection assembly GO:0030031 120 66 0,000 0,03237971 0,03448676 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,0328627 0,03498569 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,0328627 0,03497021 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,0328627 0,03495475 ! activation of MAPK activity GO:0000187 115 67 0,000 0,0328627 0,03493931 ! chromosome segregation GO:0007059 113 67 0,000 0,0328627 0,03492388 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,0328627 0,03490846 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,0328627 0,03489305 ! hexose catabolic process GO:0019320 104 67 0,000 0,0328627 0,03487766 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,0328627 0,03486228 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,0328627 0,03484692 ! adaptive immune response GO:0002250 119 67 0,000 0,0328627 0,03483157 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,0328627 0,03481623 ! amino acid transport GO:0006865 125 68 0,000 0,03334546 0,03531214 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,03334546 0,03529661 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,03334546 0,03528108 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,03334546 0,03526558 ! viral reproduction GO:0016032 134 68 0,000 0,03334546 0,03525008 ! regulation of lipase activity GO:0060191 130 68 0,000 0,03334546 0,0352346 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,03334546 0,03521913 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,033828 0,03571311 ! negative regulation of cell size GO:0045792 134 69 0,000 0,033828 0,03569744 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,033828 0,03568179 ! urogenital system development GO:0001655 137 69 0,000 0,033828 0,03566616 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,033828 0,03565054 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,033828 0,03563493 ! antigen processing and presentation GO:0019882 104 69 0,000 0,033828 0,03561933 ! amine catabolic process GO:0009310 117 71 0,000 0,03479241 0,03661878 ! reproductive structure development GO:0048608 113 71 0,000 0,03479241 0,03660277 ! humoral immune response GO:0006959 109 71 0,000 0,03479241 0,03658677 ! B cell activation GO:0042113 160 71 0,000 0,03479241 0,03657079 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,03479241 0,03655482 ! regulation of immune effector process GO:0002697 137 71 0,000 0,03479241 0,03653886 ! acute inflammatory response GO:0002526 113 72 0,000 0,03527427 0,03702875 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,03527427 0,0370126 ! carbohydrate transport GO:0008643 110 72 0,000 0,03527427 0,03699647 ! learning or memory GO:0007611 147 73 0,000 0,03575591 0,03748528 ! regulation of blood pressure GO:0008217 125 73 0,000 0,03575591 0,03746896 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,03575591 0,03745264 ! axon guidance GO:0007411 139 73 0,000 0,03575591 0,03743635 ! fertilization GO:0009566 90 73 0,000 0,03575591 0,03742006 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,03623733 0,0379074 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,03623733 0,03789092 ! neurotransmitter transport GO:0006836 123 74 0,000 0,03623733 0,03787446 ! meiosis GO:0007126 121 74 0,000 0,03623733 0,03785802 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,03623733 0,03784158 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,03623733 0,03782517 ! eye development GO:0001654 143 74 0,000 0,03623733 0,03780876 ! organelle localization GO:0051640 136 74 0,000 0,03623733 0,03779237 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,03671852 0,03827762 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,03671852 0,03826105 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,03671852 0,03824448 ! meiotic cell cycle GO:0051321 122 75 0,000 0,03671852 0,03822793 ! rhythmic process GO:0048511 128 75 0,000 0,03671852 0,0382114 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,03671852 0,03819488 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,03719949 0,03867846 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,03719949 0,03866176 ! defense response to bacterium GO:0042742 89 76 0,000 0,03719949 0,03864506 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,03719949 0,03862838 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,03719949 0,03861172 ! regulation of catabolic process GO:0009894 161 76 0,000 0,03719949 0,03859507 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,03768023 0,039077 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,03768023 0,03906016 ! blood coagulation GO:0007596 146 78 0,000 0,03816075 0,03954124 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,03816075 0,03952422 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,03816075 0,03950721 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,03816075 0,03949022 ! protein oligomerization GO:0051259 139 78 0,000 0,03816075 0,03947324 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,03864104 0,03995288 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,03864104 0,03993572 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,03864104 0,03991857 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,03864104 0,03990144 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,03912112 0,04037984 ! muscle cell differentiation GO:0042692 159 80 0,000 0,03912112 0,04036252 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,03912112 0,04034522 ! protein import into nucleus GO:0006606 158 80 0,000 0,03912112 0,04032794 ! inorganic anion transport GO:0015698 138 80 0,000 0,03912112 0,04031067 ! T cell activation GO:0042110 168 81 0,000 0,03960096 0,04078764 ! response to hypoxia GO:0001666 171 81 0,000 0,03960096 0,04077018 ! digestion GO:0007586 112 81 0,000 0,03960096 0,04075274 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,03960096 0,04073532 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,03960096 0,04071791 ! nuclear import GO:0051170 161 81 0,000 0,03960096 0,04070052 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,04008059 0,04117587 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,04008059 0,0411583 ! response to drug GO:0042493 143 82 0,000 0,04008059 0,04114074 ! response to nutrient GO:0007584 125 82 0,000 0,04008059 0,04112319 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,04008059 0,04110567 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,04008059 0,04108815 ! response to oxygen levels GO:0070482 176 83 0,000 0,04055999 0,04156189 ! regulation of lyase activity GO:0051339 160 83 0,000 0,04055999 0,0415442 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,04103916 0,04201712 ! hemostasis GO:0007599 158 84 0,000 0,04103916 0,04199925 ! negative regulation of transport GO:0051051 153 84 0,000 0,04103916 0,04198139 ! negative regulation of growth GO:0045926 155 84 0,000 0,04103916 0,04196355 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,04103916 0,04194572 ! nucleosome assembly GO:0006334 122 85 0,000 0,04151812 0,04241724 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,04151812 0,04239923 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,04151812 0,04238124 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,04199685 0,04285175 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,04199685 0,04283358 ! chromatin assembly GO:0031497 124 86 0,000 0,04199685 0,04281543 ! alcohol catabolic process GO:0046164 130 86 0,000 0,04199685 0,0427973 ! amine transport GO:0015837 155 86 0,000 0,04199685 0,04277918 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,04247536 0,04324829 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,04247536 0,04322999 ! protein localization in nucleus GO:0034504 176 87 0,000 0,04247536 0,04321171 ! cellular respiration GO:0045333 135 88 0,000 0,04295364 0,04367982 ! regulation of DNA binding GO:0051101 155 88 0,000 0,04295364 0,04366137 ! gland development GO:0048732 206 88 0,000 0,04295364 0,04364293 ! regulation of neurological system process GO:0031644 148 88 0,000 0,04295364 0,04362451 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,04295364 0,0436061 ! cellular defense response GO:0006968 114 89 0,000 0,0434317 0,04407283 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,0434317 0,04405425 ! ossification GO:0001503 188 90 0,000 0,04390954 0,04452016 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,04390954 0,04450141 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,04390954 0,04448267 ! sex differentiation GO:0007548 145 90 0,000 0,04390954 0,04446395 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,04390954 0,04444525 ! bone development GO:0060348 189 91 0,000 0,04438715 0,04490979 ! sterol metabolic process GO:0016125 152 91 0,000 0,04438715 0,04489092 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,04438715 0,04487206 ! regulation of defense response GO:0031347 149 92 0,000 0,04486455 0,04533561 ! nucleosome organization GO:0034728 138 92 0,000 0,04486455 0,04531658 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,04486455 0,04529757 ! vitamin metabolic process GO:0006766 139 92 0,000 0,04486455 0,04527856 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,04534172 0,04574095 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,04534172 0,04572178 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,04534172 0,04570263 ! regulation of membrane potential GO:0042391 164 93 0,000 0,04534172 0,04568349 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,04581866 0,04614471 ! female pregnancy GO:0007565 164 94 0,000 0,04581866 0,0461254 ! transcription initiation GO:0006352 153 94 0,000 0,04581866 0,04610611 ! regulation of T cell activation GO:0050863 158 94 0,000 0,04581866 0,04608683 ! leukocyte differentiation GO:0002521 202 96 0,000 0,04677189 0,04702598 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,04677189 0,04700634 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,04677189 0,04698671 ! positive regulation of immune response GO:0050778 156 96 0,000 0,04677189 0,0469671 ! detection of stimulus GO:0051606 151 96 0,000 0,04677189 0,04694751 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,04724817 0,0474058 ! protein ubiquitination GO:0016567 217 97 0,000 0,04724817 0,04738604 ! hormone metabolic process GO:0042445 157 97 0,000 0,04724817 0,04736629 ! response to virus GO:0009615 160 98 0,000 0,04772423 0,04782362 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,04772423 0,04780371 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,04772423 0,04778381 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,04820007 0,04824017 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,04820007 0,04822011 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,04820007 0,04820007 GO:0060538|skeletal muscle organ development,