pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/2932-3-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 1,066E-08 2,604E-05 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 1,933E-07 2,362E-04 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 2,715E-07 2,211E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,123E-06 6,856E-04 ! negative regulation of protein ubiquitination GO:0031397 10 5 1,000 1,898E-06 9,275E-04 ! anagen GO:0042640 7 5 1,000 1,898E-06 7,729E-04 ! regulation of keratinocyte differentiation GO:0045616 6 5 1,000 1,898E-06 6,625E-04 ! stem cell division GO:0017145 11 5 1,000 1,898E-06 5,797E-04 GO:0048103|somatic stem cell division, ! response to UV GO:0009411 120 55 2,000 1,935E-06 5,253E-04 ! hair follicle maturation GO:0048820 8 6 1,000 2,847E-06 6,954E-04 ! activation of Ras GTPase activity GO:0032856 13 6 1,000 2,847E-06 6,322E-04 GO:0032862|activation of Rho GTPase activity, ! ectodermal gut morphogenesis GO:0048567 16 6 1,000 2,847E-06 5,795E-04 GO:0007439|ectodermal gut development, ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,984E-06 7,487E-04 ! regulation of myoblast differentiation GO:0045661 16 7 1,000 3,984E-06 6,952E-04 ! regulation of epidermal cell differentiation GO:0045604 8 7 1,000 3,984E-06 6,489E-04 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 4,954E-06 7,564E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 5,311E-06 7,632E-04 ! negative regulation of muscle cell differentiation GO:0051148 17 8 1,000 5,311E-06 7,208E-04 ! ER overload response GO:0006983 13 8 1,000 5,311E-06 6,829E-04 ! regulation of focal adhesion formation GO:0051893 23 8 1,000 5,311E-06 6,487E-04 ! positive regulation of epidermis development GO:0045684 13 8 1,000 5,311E-06 6,178E-04 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 6,826E-06 7,58E-04 ! regulation of phosphatase activity GO:0010921 28 10 1,000 8,531E-06 9,061E-04 ! endoderm development GO:0007492 18 10 1,000 8,531E-06 8,684E-04 ! regulation of stress fiber formation GO:0051492 34 10 1,000 8,531E-06 8,336E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,042E-05 9,794E-04 ! keratinocyte proliferation GO:0043616 19 11 1,000 1,042E-05 9,432E-04 ! UV protection GO:0009650 20 11 1,000 1,042E-05 9,095E-04 ! positive regulation of Rho GTPase activity GO:0032321 31 11 1,000 1,042E-05 8,781E-04 ! regulation of actin filament bundle formation GO:0032231 37 11 1,000 1,042E-05 8,488E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 1,109E-05 8,738E-04 ! positive regulation of cell growth GO:0030307 24 13 1,000 1,478E-05 1,128E-03 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,478E-05 1,094E-03 ! regulation of epidermis development GO:0045682 19 13 1,000 1,478E-05 1,062E-03 ! digestive tract morphogenesis GO:0048546 31 13 1,000 1,478E-05 1,031E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! hair follicle morphogenesis GO:0031069 27 14 1,000 1,723E-05 1,169E-03 ! negative regulation of caspase activity GO:0043154 23 14 1,000 1,723E-05 1,138E-03 ! positive regulation of Ras GTPase activity GO:0032320 42 14 1,000 1,723E-05 1,108E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 1,723E-05 1,079E-03 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 1,988E-05 1,214E-03 ! positive regulation of GTPase activity GO:0043547 43 15 1,000 1,988E-05 1,185E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 1,988E-05 1,156E-03 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 2,271E-05 1,29E-03 ! positive regulation of cell size GO:0045793 29 16 1,000 2,271E-05 1,261E-03 ! embryonic hindlimb morphogenesis GO:0035116 36 16 1,000 2,271E-05 1,233E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 2,271E-05 1,206E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 1,000 2,271E-05 1,181E-03 ! regulation of muscle cell differentiation GO:0051147 36 17 1,000 2,573E-05 1,31E-03 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 2,573E-05 1,283E-03 ! epidermis morphogenesis GO:0048730 43 18 1,000 2,894E-05 1,414E-03 ! skin development GO:0043588 42 20 1,000 3,592E-05 1,721E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 3,592E-05 1,688E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 3,592E-05 1,656E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 3,592E-05 1,625E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 3,592E-05 1,596E-03 ! negative regulation of translation GO:0017148 32 20 1,000 3,592E-05 1,567E-03 ! hindlimb morphogenesis GO:0035137 47 22 1,000 4,365E-05 1,871E-03 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 4,365E-05 1,839E-03 ! peptidyl-serine modification GO:0018209 50 22 1,000 4,365E-05 1,808E-03 ! gut development GO:0048565 44 22 1,000 4,365E-05 1,777E-03 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 4,78E-05 1,914E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of Rho GTPase activity GO:0032319 56 23 1,000 4,78E-05 1,883E-03 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 5,213E-05 2,022E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 5,665E-05 2,162E-03 ! molting cycle process GO:0022404 52 26 1,000 6,135E-05 2,306E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! neuron fate commitment GO:0048663 52 28 1,000 7,132E-05 2,64E-03 ! negative regulation of protein modification process GO:0031400 66 28 1,000 7,132E-05 2,601E-03 ! fat cell differentiation GO:0045444 57 28 1,000 7,132E-05 2,562E-03 ! base-excision repair GO:0006284 41 28 1,000 7,132E-05 2,525E-03 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 7,658E-05 2,673E-03 ! determination of left/right symmetry GO:0007368 53 30 1,000 8,203E-05 2,823E-03 ! determination of bilateral symmetry GO:0009855 55 31 1,000 8,767E-05 2,975E-03 GO:0009799|determination of symmetry, ! glial cell differentiation GO:0010001 67 34 1,000 1,057E-04 3,537E-03 ! cell fate specification GO:0001708 56 34 1,000 1,057E-04 3,489E-03 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 1,121E-04 3,65E-03 ! regulation of muscle development GO:0048634 82 36 1,000 1,186E-04 3,813E-03 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 1,186E-04 3,763E-03 ! glycogen metabolic process GO:0005977 63 38 1,000 1,323E-04 4,144E-03 ! glucan metabolic process GO:0044042 64 39 1,000 1,394E-04 4,311E-03 GO:0006073|cellular glucan metabolic process, ! RNA export from nucleus GO:0006405 61 41 1,000 1,542E-04 4,709E-03 ! gliogenesis GO:0042063 91 41 1,000 1,542E-04 4,65E-03 ! mesenchymal cell development GO:0014031 94 41 1,000 1,542E-04 4,594E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 86 42 1,000 1,619E-04 4,764E-03 ! energy reserve metabolic process GO:0006112 76 44 1,000 1,777E-04 5,169E-03 ! double-strand break repair GO:0006302 85 44 1,000 1,777E-04 5,109E-03 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 1,86E-04 5,283E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 1,86E-04 5,222E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 1,86E-04 5,163E-03 ! keratinocyte differentiation GO:0030216 81 45 1,000 1,86E-04 5,105E-03 ! developmental growth GO:0048589 88 45 1,000 1,86E-04 5,048E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 1,944E-04 5,218E-03 ! positive regulation of protein transport GO:0051222 80 46 1,000 1,944E-04 5,161E-03 ! response to insulin stimulus GO:0032868 98 47 1,000 2,029E-04 5,331E-03 ! positive regulation of cell cycle GO:0045787 96 48 1,000 2,117E-04 5,502E-03 ! response to calcium ion GO:0051592 94 49 1,000 2,207E-04 5,675E-03 ! epidermal cell differentiation GO:0009913 87 50 1,000 2,298E-04 5,848E-03 ! Notch signaling pathway GO:0007219 111 52 1,000 2,486E-04 6,262E-03 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 2,486E-04 6,198E-03 ! positive regulation of growth GO:0045927 96 53 1,000 2,583E-04 6,374E-03 ! regulation of DNA replication GO:0006275 105 56 1,000 2,884E-04 7,047E-03 ! nucleotide-excision repair GO:0006289 91 57 1,000 2,988E-04 7,229E-03 ! regulation of intracellular transport GO:0032386 108 57 1,000 2,988E-04 7,158E-03 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 3,094E-04 7,339E-03 ! nuclear export GO:0051168 110 59 1,000 3,202E-04 7,522E-03 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 3,536E-04 8,228E-03 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 3,768E-04 8,684E-03 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 4,129E-04 9,428E-03 GO:0035113|embryonic appendage morphogenesis, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 4,253E-04 9,621E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 4,379E-04 9,815E-03 ! lung development GO:0030324 165 69 1,000 4,379E-04 9,725E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 4,379E-04 9,638E-03 ! developmental maturation GO:0021700 128 69 1,000 4,379E-04 9,552E-03 ! negative regulation of kinase activity GO:0033673 145 70 1,000 4,507E-04 9,743E-03 ! appendage morphogenesis GO:0035107 150 72 1,000 4,767E-04 0,0102162 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 1,000 4,767E-04 0,01012736 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 4,767E-04 0,01004006 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 4,767E-04 9,954E-03 ! appendage development GO:0048736 151 73 1,000 4,9E-04 0,01014525 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 5,035E-04 0,01033673 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 5,035E-04 0,01025059 ! negative regulation of transferase activity GO:0051348 155 74 1,000 5,035E-04 0,01016587 ! respiratory system development GO:0060541 175 74 1,000 5,035E-04 0,01008254 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 5,31E-04 0,01054672 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 5,45E-04 0,01073782 ! positive regulation of ligase activity GO:0051351 130 77 1,000 5,45E-04 0,01065192 ! regulation of actin filament-based process GO:0032970 170 79 1,000 5,736E-04 0,01112133 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 5,736E-04 0,01103376 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 6,029E-04 0,01150649 ! regulation of peptidase activity GO:0052547 150 82 1,000 6,178E-04 0,01169965 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 6,329E-04 0,01189319 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 6,481E-04 0,01208709 ! regulation of ligase activity GO:0051340 147 84 1,000 6,481E-04 0,01199553 ! regulation of neuron differentiation GO:0045664 187 85 1,000 6,636E-04 0,01218901 ! mitochondrion organization GO:0007005 159 87 1,000 6,95E-04 0,01267088 ! regulation of protein transport GO:0051223 165 87 1,000 6,95E-04 0,01257703 GO:0070201|regulation of establishment of protein localization, ! tube morphogenesis GO:0035239 194 89 1,000 7,271E-04 0,01306171 ! response to inorganic substance GO:0010035 173 90 1,000 7,435E-04 0,01325758 ! positive regulation of protein modification process GO:0031401 156 90 1,000 7,435E-04 0,01316151 ! response to unfolded protein GO:0006986 139 90 1,000 7,435E-04 0,01306682 ! regulation of cell adhesion GO:0030155 241 92 1,000 7,767E-04 0,01355269 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 7,935E-04 0,01374871 GO:0010498|proteasomal protein catabolic process, ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 8,278E-04 0,01424117 ! response to protein stimulus GO:0051789 158 96 1,000 8,452E-04 0,01443867 ! regulation of protein localization GO:0032880 188 97 1,000 8,627E-04 0,01463643 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 8,627E-04 0,01453549 ! forebrain development GO:0030900 210 98 1,000 8,805E-04 0,01473281 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 2,249E-03 0,03737345 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 2,249E-03 0,03712093 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 2,249E-03 0,0368718 ! positive regulation of helicase activity GO:0051096 12 5 0,000 2,249E-03 0,03662599 ! neuron fate determination GO:0048664 7 5 0,000 2,249E-03 0,03638343 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,249E-03 0,03614406 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 2,249E-03 0,03590783 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 2,249E-03 0,03567466 ! polyol transport GO:0015791 12 5 0,000 2,249E-03 0,0354445 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 2,249E-03 0,03521729 ! response to superoxide GO:0000303 10 5 0,000 2,249E-03 0,03499298 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,249E-03 0,03477151 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 2,249E-03 0,03455282 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 2,249E-03 0,03433686 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 2,249E-03 0,03412359 ! female meiosis GO:0007143 10 5 0,000 2,249E-03 0,03391295 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 2,249E-03 0,03370489 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 2,249E-03 0,03349938 ! hypothalamus development GO:0021854 9 5 0,000 2,249E-03 0,03329635 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 2,249E-03 0,03309577 ! cobalt ion transport GO:0006824 11 5 0,000 2,249E-03 0,03289759 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 2,249E-03 0,03270177 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 2,249E-03 0,03250827 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 2,249E-03 0,03231705 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 2,249E-03 0,03212806 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 2,249E-03 0,03194127 ! embryonic camera-type eye development GO:0031076 12 5 0,000 2,249E-03 0,03175663 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 2,249E-03 0,03157413 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,249E-03 0,0313937 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 2,249E-03 0,03121533 ! transposition GO:0032196 9 5 0,000 2,249E-03 0,03103897 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 2,249E-03 0,03086459 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 2,249E-03 0,03069217 ! negative chemotaxis GO:0050919 16 5 0,000 2,249E-03 0,03052165 ! positive regulation of histone modification GO:0031058 6 5 0,000 2,249E-03 0,03035303 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 2,249E-03 0,03018625 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 2,249E-03 0,0300213 ! behavioral response to pain GO:0048266 10 5 0,000 2,249E-03 0,02985814 ! clathrin coat assembly GO:0048268 15 5 0,000 2,249E-03 0,02969674 ! Notch receptor processing GO:0007220 11 5 0,000 2,249E-03 0,02953709 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,249E-03 0,02937913 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 2,249E-03 0,02922286 ! micturition GO:0060073 9 5 0,000 2,249E-03 0,02906824 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 2,249E-03 0,02891525 ! copulation GO:0007620 9 5 0,000 2,249E-03 0,02876386 ! glial cell fate commitment GO:0021781 14 5 0,000 2,249E-03 0,02861405 ! protein maturation by protein folding GO:0022417 14 5 0,000 2,249E-03 0,02846579 ! bioluminescence GO:0008218 9 5 0,000 2,249E-03 0,02831906 ! spermidine metabolic process GO:0008216 7 5 0,000 2,249E-03 0,02817383 ! regulation of potassium ion transport GO:0043266 10 5 0,000 2,249E-03 0,02803009 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 2,249E-03 0,02788781 ! apoptotic cell clearance GO:0043277 23 5 0,000 2,249E-03 0,02774696 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 2,249E-03 0,02760753 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 2,249E-03 0,02746949 ! lipoprotein particle clearance GO:0034381 10 5 0,000 2,249E-03 0,02733282 ! grooming behavior GO:0007625 6 5 0,000 2,249E-03 0,02719751 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 2,249E-03 0,02706354 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 2,249E-03 0,02693087 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 2,249E-03 0,0267995 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,249E-03 0,02666941 ! response to protozoan GO:0001562 13 5 0,000 2,249E-03 0,02654057 ! positive regulation of glycolysis GO:0045821 13 5 0,000 2,249E-03 0,02641297 ! lymph vessel development GO:0001945 10 5 0,000 2,249E-03 0,02628659 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 2,249E-03 0,02616142 ! endochondral ossification GO:0001958 17 5 0,000 2,249E-03 0,02603743 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 2,249E-03 0,02591461 ! single strand break repair GO:0000012 8 5 0,000 2,249E-03 0,02579295 ! parathyroid gland development GO:0060017 14 5 0,000 2,249E-03 0,02567242 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 2,249E-03 0,02555301 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 2,249E-03 0,02543471 ! cytokine secretion GO:0050663 15 5 0,000 2,249E-03 0,0253175 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 2,249E-03 0,02520137 ! ceramide catabolic process GO:0046514 7 5 0,000 2,249E-03 0,02508629 ! skeletal myofibril assembly GO:0014866 12 5 0,000 2,249E-03 0,02497226 ! smooth muscle tissue development GO:0048745 32 5 0,000 2,249E-03 0,02485927 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 2,249E-03 0,02474729 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 2,249E-03 0,02463631 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 2,249E-03 0,02452633 ! cardiac muscle fiber development GO:0048739 12 5 0,000 2,249E-03 0,02441732 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 2,249E-03 0,02430928 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 2,249E-03 0,02420219 ! neutrophil mediated immunity GO:0002446 7 5 0,000 2,249E-03 0,02409604 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 2,249E-03 0,02399082 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 2,249E-03 0,02388651 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 2,249E-03 0,02378311 ! glycine biosynthetic process GO:0006545 7 5 0,000 2,249E-03 0,02368059 ! microvillus organization GO:0032528 8 5 0,000 2,249E-03 0,02357896 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 2,249E-03 0,0234782 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 2,249E-03 0,02337829 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 2,249E-03 0,02327923 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 2,249E-03 0,023181 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 2,249E-03 0,0230836 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 2,249E-03 0,02298702 ! polyol catabolic process GO:0046174 9 5 0,000 2,249E-03 0,02289124 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 2,249E-03 0,02279626 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 2,249E-03 0,02270206 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 2,249E-03 0,02260863 ! muscle cell migration GO:0014812 8 5 0,000 2,249E-03 0,02251597 ! mitochondrial fission GO:0000266 8 5 0,000 2,249E-03 0,02242407 ! sister chromatid cohesion GO:0007062 15 5 0,000 2,249E-03 0,02233292 ! response to tumor necrosis factor GO:0034612 10 5 0,000 2,249E-03 0,0222425 ! mRNA transcription GO:0009299 10 5 0,000 2,249E-03 0,02215281 ! nerve growth factor processing GO:0032455 9 5 0,000 2,249E-03 0,02206385 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 2,249E-03 0,02197559 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 2,249E-03 0,02188804 ! anaerobic glycolysis GO:0019642 6 5 0,000 2,249E-03 0,02180118 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 2,249E-03 0,02171501 ! monocyte activation GO:0042117 10 5 0,000 2,249E-03 0,02162952 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 2,249E-03 0,0215447 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 2,249E-03 0,02146054 ! response to food GO:0032094 6 5 0,000 2,249E-03 0,02137703 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 2,249E-03 0,02129418 ! positive regulation of transporter activity GO:0032411 8 5 0,000 2,249E-03 0,02121196 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 2,249E-03 0,02113038 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,249E-03 0,02104942 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 2,249E-03 0,02096908 ! forebrain neuron development GO:0021884 13 5 0,000 2,249E-03 0,02088935 ! lipoprotein catabolic process GO:0042159 11 5 0,000 2,249E-03 0,02081022 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 2,249E-03 0,02073169 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 2,249E-03 0,02065375 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 2,249E-03 0,0205764 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,249E-03 0,02049962 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 2,249E-03 0,02042341 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 2,249E-03 0,02034777 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 2,249E-03 0,02027269 ! lipid glycosylation GO:0030259 7 5 0,000 2,249E-03 0,02019815 ! nucleobase transport GO:0015851 6 5 0,000 2,249E-03 0,02012417 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,249E-03 0,02005072 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 2,249E-03 0,01997781 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 2,249E-03 0,01990543 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 2,249E-03 0,01983357 ! basic amino acid transport GO:0015802 12 5 0,000 2,249E-03 0,01976222 ! cellular glucose homeostasis GO:0001678 6 5 0,000 2,249E-03 0,01969139 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 2,249E-03 0,01962106 ! actin nucleation GO:0045010 11 5 0,000 2,249E-03 0,01955124 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,249E-03 0,01948191 ! depurination GO:0045007 5 5 0,000 2,249E-03 0,01941307 ! depyrimidination GO:0045008 10 5 0,000 2,249E-03 0,01934471 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 2,249E-03 0,01927683 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,249E-03 0,01920943 ! G2/M transition checkpoint GO:0031576 8 5 0,000 2,249E-03 0,0191425 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 2,249E-03 0,01907603 ! zinc ion homeostasis GO:0055069 9 5 0,000 2,249E-03 0,01901003 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 2,249E-03 0,01894448 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 2,249E-03 0,01887937 ! forebrain morphogenesis GO:0048853 13 5 0,000 2,249E-03 0,01881472 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 2,249E-03 0,0187505 ! activated T cell proliferation GO:0050798 16 5 0,000 2,249E-03 0,01868673 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 2,249E-03 0,01862338 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 2,249E-03 0,01856047 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,249E-03 0,01849797 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,249E-03 0,0184359 ! gamma-delta T cell activation GO:0046629 6 5 0,000 2,249E-03 0,01837424 ! response to arsenic GO:0046685 11 5 0,000 2,249E-03 0,01831299 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 2,249E-03 0,01825215 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 2,249E-03 0,01819171 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 2,249E-03 0,01813168 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 2,249E-03 0,01807203 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 2,249E-03 0,01801278 ! response to mercury ion GO:0046689 8 5 0,000 2,249E-03 0,01795391 ! response to cadmium ion GO:0046686 7 5 0,000 2,249E-03 0,01789543 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 2,249E-03 0,01783733 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 2,249E-03 0,0177796 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 2,249E-03 0,01772225 ! bile acid biosynthetic process GO:0006699 7 5 0,000 2,249E-03 0,01766527 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 2,249E-03 0,01760865 ! ganglioside catabolic process GO:0006689 12 5 0,000 2,249E-03 0,01755239 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 2,249E-03 0,01749649 ! decidualization GO:0046697 11 5 0,000 2,249E-03 0,01744095 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 2,249E-03 0,01738575 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 2,249E-03 0,01733091 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 2,249E-03 0,01727641 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 2,249E-03 0,01722225 ! embryonic cleavage GO:0040016 6 5 0,000 2,249E-03 0,01716843 ! peroxisome fission GO:0016559 5 5 0,000 2,249E-03 0,01711495 ! histone demethylation GO:0016577 13 5 0,000 2,249E-03 0,01706179 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 2,249E-03 0,01700897 ! mitotic recombination GO:0006312 9 5 0,000 2,249E-03 0,01695647 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 2,249E-03 0,0169043 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,249E-03 0,01685245 ! metaphase plate congression GO:0051310 7 5 0,000 2,249E-03 0,01680091 ! regulation of sterol transport GO:0032371 7 5 0,000 2,249E-03 0,01674969 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 2,249E-03 0,01669878 ! enteric nervous system development GO:0048484 8 5 0,000 2,249E-03 0,01664818 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 2,249E-03 0,01659788 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 2,249E-03 0,01654789 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 2,249E-03 0,01649819 ! muscle cell proliferation GO:0033002 12 5 0,000 2,249E-03 0,0164488 ! skeletal muscle regeneration GO:0043403 8 5 0,000 2,249E-03 0,01639969 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 2,249E-03 0,01635089 ! B cell homeostasis GO:0001782 13 5 0,000 2,249E-03 0,01630237 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 2,249E-03 0,01625414 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 2,249E-03 0,01620619 ! metaphase GO:0051323 11 5 0,000 2,249E-03 0,01615852 ! melatonin biosynthetic process GO:0030187 7 5 0,000 2,249E-03 0,01611114 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 2,249E-03 0,01606403 ! cellular response to nutrient GO:0031670 8 5 0,000 2,249E-03 0,01601719 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 2,249E-03 0,01597063 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 2,249E-03 0,01592434 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 2,249E-03 0,01587832 ! regulation of hair follicle development GO:0051797 10 5 0,000 2,249E-03 0,01583256 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 2,249E-03 0,01578706 ! response to redox state GO:0051775 6 5 0,000 2,249E-03 0,01574183 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 2,249E-03 0,01569685 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 2,249E-03 0,01565213 ! brown fat cell differentiation GO:0050873 7 5 0,000 2,249E-03 0,01560766 ! regulation of telomerase activity GO:0051972 7 5 0,000 2,249E-03 0,01556345 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,249E-03 0,01551949 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 2,249E-03 0,01547577 ! porphyrin catabolic process GO:0006787 12 5 0,000 2,249E-03 0,0154323 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 2,249E-03 0,01538907 ! striatum development GO:0021756 14 5 0,000 2,249E-03 0,01534608 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 2,249E-03 0,01530334 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 2,249E-03 0,01526083 ! glial cell migration GO:0008347 10 5 0,000 2,249E-03 0,01521855 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 2,249E-03 0,01517651 ! neural plate morphogenesis GO:0001839 7 5 0,000 2,249E-03 0,0151347 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 2,249E-03 0,01509313 ! somatic stem cell maintenance GO:0035019 15 5 0,000 2,249E-03 0,01505177 ! T cell activation during immune response GO:0002286 9 5 0,000 2,249E-03 0,01501065 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 2,249E-03 0,01496975 ! negative regulation of lipase activity GO:0060192 8 5 0,000 2,249E-03 0,01492907 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 2,249E-03 0,01488861 ! neuroprotection GO:0043526 8 5 0,000 2,249E-03 0,01484837 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 2,249E-03 0,01480835 ! regulation of sensory perception GO:0051931 8 5 0,000 2,249E-03 0,01476854 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 2,249E-03 0,01472895 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 2,249E-03 0,01468957 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 2,249E-03 0,01465039 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 2,249E-03 0,01461143 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 2,249E-03 0,01457267 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 2,249E-03 0,01453412 ! sequestering of calcium ion GO:0051208 7 5 0,000 2,249E-03 0,01449577 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 2,249E-03 0,01445763 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 2,249E-03 0,01441968 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 2,249E-03 0,01438193 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 2,249E-03 0,01434438 ! spindle assembly GO:0051225 6 5 0,000 2,249E-03 0,01430703 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 2,249E-03 0,01426986 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 2,249E-03 0,0142329 ! protein palmitoylation GO:0018345 12 5 0,000 2,249E-03 0,01419612 ! drug metabolic process GO:0017144 7 5 0,000 2,249E-03 0,01415953 ! phospholipid scrambling GO:0017121 8 5 0,000 2,249E-03 0,01412313 ! organ regeneration GO:0031100 7 5 0,000 2,249E-03 0,01408692 ! carnitine metabolic process GO:0009437 8 5 0,000 2,249E-03 0,01405089 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 2,249E-03 0,01401505 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 2,698E-03 0,01677172 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 2,698E-03 0,01672915 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 2,698E-03 0,0166868 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 2,698E-03 0,01664466 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 2,698E-03 0,01660274 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 2,698E-03 0,01656102 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 2,698E-03 0,01651952 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 2,698E-03 0,01647822 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 2,698E-03 0,01643712 ! response to oxygen radical GO:0000305 11 6 0,000 2,698E-03 0,01639624 ! positive regulation of axon extension GO:0045773 13 6 0,000 2,698E-03 0,01635555 ! myoblast cell fate commitment GO:0048625 18 6 0,000 2,698E-03 0,01631507 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 2,698E-03 0,01627478 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 2,698E-03 0,0162347 ! regulation of interferon-beta production GO:0032648 8 6 0,000 2,698E-03 0,01619481 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 2,698E-03 0,01615511 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 2,698E-03 0,01611562 ! forebrain regionalization GO:0021871 9 6 0,000 2,698E-03 0,01607631 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 2,698E-03 0,01603719 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 2,698E-03 0,01599827 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 2,698E-03 0,01595953 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 2,698E-03 0,01592098 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 2,698E-03 0,01588262 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 2,698E-03 0,01584444 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 2,698E-03 0,01580644 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 2,698E-03 0,01576863 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 2,698E-03 0,01573099 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 2,698E-03 0,01569354 ! malate metabolic process GO:0006108 13 6 0,000 2,698E-03 0,01565626 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 2,698E-03 0,01561916 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 2,698E-03 0,01558224 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 2,698E-03 0,01554549 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 2,698E-03 0,01550891 ! protein refolding GO:0042026 15 6 0,000 2,698E-03 0,0154725 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 2,698E-03 0,01543627 ! opsonization GO:0008228 8 6 0,000 2,698E-03 0,0154002 ! mating behavior GO:0007617 7 6 0,000 2,698E-03 0,0153643 ! erythrocyte maturation GO:0043249 8 6 0,000 2,698E-03 0,01532857 ! embryonic hemopoiesis GO:0035162 16 6 0,000 2,698E-03 0,01529301 ! protein amino acid dealkylation GO:0008214 15 6 0,000 2,698E-03 0,01525761 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 2,698E-03 0,01522237 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 2,698E-03 0,0151873 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 2,698E-03 0,01515238 ! response to interferon-gamma GO:0034341 16 6 0,000 2,698E-03 0,01511763 ! toxin metabolic process GO:0009404 11 6 0,000 2,698E-03 0,01508304 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 2,698E-03 0,0150486 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 2,698E-03 0,01501432 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 2,698E-03 0,0149802 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 2,698E-03 0,01494623 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 2,698E-03 0,01491241 ! cGMP-mediated signaling GO:0019934 14 6 0,000 2,698E-03 0,01487875 ! dorsal spinal cord development GO:0021516 10 6 0,000 2,698E-03 0,01484524 ! activation of MAPKKK activity GO:0000185 12 6 0,000 2,698E-03 0,01481188 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 2,698E-03 0,01477867 ! thymic T cell selection GO:0045061 16 6 0,000 2,698E-03 0,01474561 ! sphingoid catabolic process GO:0046521 8 6 0,000 2,698E-03 0,01471269 ! protein lipoylation GO:0009249 10 6 0,000 2,698E-03 0,01467993 ! transepithelial chloride transport GO:0030321 12 6 0,000 2,698E-03 0,0146473 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 2,698E-03 0,01461483 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 2,698E-03 0,01458249 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 2,698E-03 0,0145503 ! glutamate catabolic process GO:0006538 12 6 0,000 2,698E-03 0,01451825 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 2,698E-03 0,01448634 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 2,698E-03 0,01445458 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 2,698E-03 0,01442295 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 2,698E-03 0,01439146 ! hyperosmotic response GO:0006972 10 6 0,000 2,698E-03 0,0143601 ! L-serine biosynthetic process GO:0006564 7 6 0,000 2,698E-03 0,01432888 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 2,698E-03 0,0142978 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 2,698E-03 0,01426685 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 2,698E-03 0,01423604 ! urea metabolic process GO:0019627 7 6 0,000 2,698E-03 0,01420536 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 2,698E-03 0,01417481 ! neutrophil activation GO:0042119 7 6 0,000 2,698E-03 0,01414439 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 2,698E-03 0,0141141 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 2,698E-03 0,01408395 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 2,698E-03 0,01405392 ! paraxial mesoderm development GO:0048339 16 6 0,000 2,698E-03 0,01402401 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 2,698E-03 0,01399424 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 2,698E-03 0,01396459 ! neuron apoptosis GO:0051402 15 6 0,000 2,698E-03 0,01393507 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 2,698E-03 0,01390567 ! T cell mediated immunity GO:0002456 17 6 0,000 2,698E-03 0,01387639 ! negative regulation of platelet activation GO:0010544 9 6 0,000 2,698E-03 0,01384724 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 2,698E-03 0,01381821 ! carnitine transport GO:0015879 10 6 0,000 2,698E-03 0,0137893 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,698E-03 0,01376051 ! positive regulation of exocytosis GO:0045921 11 6 0,000 2,698E-03 0,01373185 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 2,698E-03 0,0137033 ! early endosome to late endosome transport GO:0045022 16 6 0,000 2,698E-03 0,01367487 ! 5S class rRNA transcription GO:0042791 13 6 0,000 2,698E-03 0,01364656 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 2,698E-03 0,01361836 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 2,698E-03 0,01359028 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 2,698E-03 0,01356232 ! sodium ion homeostasis GO:0055078 12 6 0,000 2,698E-03 0,01353447 ! establishment of spindle localization GO:0051293 16 6 0,000 2,698E-03 0,01350673 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 2,698E-03 0,01347911 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 2,698E-03 0,01345161 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 2,698E-03 0,01342421 ! response to UV-C GO:0010225 14 6 0,000 2,698E-03 0,01339692 ! astrocyte development GO:0014002 16 6 0,000 2,698E-03 0,01336975 ! protein targeting to lysosome GO:0006622 12 6 0,000 2,698E-03 0,01334269 ! purine base biosynthetic process GO:0009113 17 6 0,000 2,698E-03 0,01331573 ! interaction with symbiont GO:0051702 14 6 0,000 2,698E-03 0,01328888 ! regulation of dendrite development GO:0050773 16 6 0,000 2,698E-03 0,01326215 ! peptidyl-arginine modification GO:0018195 13 6 0,000 2,698E-03 0,01323552 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 2,698E-03 0,01320899 ! response to copper ion GO:0046688 10 6 0,000 2,698E-03 0,01318257 ! response to exogenous dsRNA GO:0043330 13 6 0,000 2,698E-03 0,01315626 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 2,698E-03 0,01313005 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,698E-03 0,01310395 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 2,698E-03 0,01307795 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 2,698E-03 0,01305205 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 2,698E-03 0,01302626 ! regulation of dopamine secretion GO:0014059 14 6 0,000 2,698E-03 0,01300057 ! nucleoside catabolic process GO:0009164 10 6 0,000 2,698E-03 0,01297497 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 2,698E-03 0,01294948 ! Schwann cell development GO:0014044 15 6 0,000 2,698E-03 0,01292409 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 2,698E-03 0,0128988 ! response to pheromone GO:0019236 6 6 0,000 2,698E-03 0,01287361 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 2,698E-03 0,01284851 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 2,698E-03 0,01282351 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 2,698E-03 0,01279861 ! base conversion or substitution editing GO:0016553 6 6 0,000 2,698E-03 0,01277381 ! subpallium development GO:0021544 15 6 0,000 2,698E-03 0,0127491 ! neural tube patterning GO:0021532 8 6 0,000 2,698E-03 0,01272449 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 2,698E-03 0,01269997 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 2,698E-03 0,01267555 ! maintenance of organ identity GO:0048496 9 6 0,000 2,698E-03 0,01265122 ! G2 phase GO:0051319 16 6 0,000 2,698E-03 0,01262699 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 2,698E-03 0,01260284 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 2,698E-03 0,01257879 ! oxygen homeostasis GO:0032364 10 6 0,000 2,698E-03 0,01255483 ! establishment of planar polarity GO:0001736 7 6 0,000 2,698E-03 0,01253096 ! regulation of mast cell activation GO:0033003 13 6 0,000 2,698E-03 0,01250719 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 2,698E-03 0,0124835 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 2,698E-03 0,0124599 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 2,698E-03 0,01243639 ! receptor internalization GO:0031623 11 6 0,000 2,698E-03 0,01241297 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 2,698E-03 0,01238964 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 2,698E-03 0,01236639 ! neutrophil homeostasis GO:0001780 11 6 0,000 2,698E-03 0,01234323 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,698E-03 0,01232016 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 2,698E-03 0,01229718 ! protein deubiquitination GO:0016579 16 6 0,000 2,698E-03 0,01227428 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 2,698E-03 0,01225146 ! protein destabilization GO:0031648 9 6 0,000 2,698E-03 0,01222873 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 2,698E-03 0,01220609 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 2,698E-03 0,01218352 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 2,698E-03 0,01216105 ! regulation of viral transcription GO:0046782 11 6 0,000 2,698E-03 0,01213865 ! progesterone metabolic process GO:0042448 12 6 0,000 2,698E-03 0,01211634 ! negative regulation of axon extension GO:0030517 24 6 0,000 2,698E-03 0,0120941 ! removal of superoxide radicals GO:0019430 12 6 0,000 2,698E-03 0,01207195 ! triglyceride catabolic process GO:0019433 10 6 0,000 2,698E-03 0,01204988 ! determination of adult lifespan GO:0008340 17 6 0,000 2,698E-03 0,0120279 ! cerebellar cortex formation GO:0021697 8 6 0,000 2,698E-03 0,01200599 ! neural plate development GO:0001840 9 6 0,000 2,698E-03 0,01198416 ! catecholamine transport GO:0051937 9 6 0,000 2,698E-03 0,01196241 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 2,698E-03 0,01194074 ! sensory cilium assembly GO:0035058 10 6 0,000 2,698E-03 0,01191914 ! organ or tissue specific immune response GO:0002251 8 6 0,000 2,698E-03 0,01189763 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 2,698E-03 0,01187619 ! maternal placenta development GO:0001893 12 6 0,000 2,698E-03 0,01185483 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 2,698E-03 0,01183355 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 2,698E-03 0,01181234 ! negative regulation of B cell activation GO:0050869 14 6 0,000 2,698E-03 0,01179121 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 2,698E-03 0,01177015 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 2,698E-03 0,01174917 ! positive regulation of coagulation GO:0050820 13 6 0,000 2,698E-03 0,01172827 ! cellular anion homeostasis GO:0030002 11 6 0,000 2,698E-03 0,01170744 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 3,147E-03 0,01363158 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 3,147E-03 0,01360745 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 3,147E-03 0,01358341 ! behavioral response to cocaine GO:0048148 14 7 0,000 3,147E-03 0,01355946 ! regulation of helicase activity GO:0051095 16 7 0,000 3,147E-03 0,01353558 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 3,147E-03 0,0135118 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 3,147E-03 0,01348809 ! sleep GO:0030431 16 7 0,000 3,147E-03 0,01346447 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 3,147E-03 0,01344093 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 3,147E-03 0,01341747 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 3,147E-03 0,0133941 ! prostate gland development GO:0030850 14 7 0,000 3,147E-03 0,0133708 ! nucleotide-sugar transport GO:0015780 11 7 0,000 3,147E-03 0,01334759 ! synaptonemal complex assembly GO:0007130 10 7 0,000 3,147E-03 0,01332446 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 3,147E-03 0,0133014 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 3,147E-03 0,01327843 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 3,147E-03 0,01325554 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 3,147E-03 0,01323272 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 3,147E-03 0,01320999 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 3,147E-03 0,01318733 ! SMAD protein complex assembly GO:0007183 13 7 0,000 3,147E-03 0,01316475 ! glycolipid transport GO:0046836 11 7 0,000 3,147E-03 0,01314224 ! protein amino acid sulfation GO:0006477 10 7 0,000 3,147E-03 0,01311982 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 3,147E-03 0,01309747 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 3,147E-03 0,01307519 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 3,147E-03 0,01305299 ! establishment of tissue polarity GO:0007164 8 7 0,000 3,147E-03 0,01303087 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 3,147E-03 0,01300882 ! mRNA stabilization GO:0048255 18 7 0,000 3,147E-03 0,01298684 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 3,147E-03 0,01296494 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 3,147E-03 0,01294312 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 3,147E-03 0,01292136 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 3,147E-03 0,01289968 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 3,147E-03 0,01287808 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 3,147E-03 0,01285654 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 3,147E-03 0,01283508 ! lipoprotein transport GO:0042953 14 7 0,000 3,147E-03 0,01281369 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 3,147E-03 0,01279237 ! rhythmic behavior GO:0007622 17 7 0,000 3,147E-03 0,01277112 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 3,147E-03 0,01274994 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 3,147E-03 0,01272883 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 3,147E-03 0,01270779 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 3,147E-03 0,01268682 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 3,147E-03 0,01266592 ! regulation of odontogenesis GO:0042481 14 7 0,000 3,147E-03 0,01264509 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 3,147E-03 0,01262432 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 3,147E-03 0,01260363 ! mechanosensory behavior GO:0007638 16 7 0,000 3,147E-03 0,012583 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 3,147E-03 0,01256244 ! positive regulation of isotype switching GO:0045830 17 7 0,000 3,147E-03 0,01254194 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 3,147E-03 0,01252152 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 3,147E-03 0,01250116 ! protein-cofactor linkage GO:0018065 13 7 0,000 3,147E-03 0,01248086 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 3,147E-03 0,01246064 ! spinal cord patterning GO:0021511 14 7 0,000 3,147E-03 0,01244047 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 3,147E-03 0,01242037 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 3,147E-03 0,01240034 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 3,147E-03 0,01238037 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 3,147E-03 0,01236047 ! adrenal gland development GO:0030325 17 7 0,000 3,147E-03 0,01234063 ! cysteine metabolic process GO:0006534 13 7 0,000 3,147E-03 0,01232085 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 3,147E-03 0,01230114 ! ovulation GO:0030728 10 7 0,000 3,147E-03 0,01228149 ! adenohypophysis development GO:0021984 11 7 0,000 3,147E-03 0,0122619 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 3,147E-03 0,01224238 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 3,147E-03 0,01222291 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 3,147E-03 0,01220351 ! microtubule nucleation GO:0007020 21 7 0,000 3,147E-03 0,01218417 ! proline biosynthetic process GO:0006561 10 7 0,000 3,147E-03 0,01216489 ! tryptophan metabolic process GO:0006568 11 7 0,000 3,147E-03 0,01214567 ! thyroid hormone generation GO:0006590 13 7 0,000 3,147E-03 0,01212652 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 3,147E-03 0,01210742 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 3,147E-03 0,01208838 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 3,147E-03 0,01206941 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 3,147E-03 0,01205049 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 3,147E-03 0,01203163 ! galactose metabolic process GO:0006012 13 7 0,000 3,147E-03 0,01201283 ! vesicle fusion GO:0006906 20 7 0,000 3,147E-03 0,01199409 ! response to dietary excess GO:0002021 8 7 0,000 3,147E-03 0,01197541 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 3,147E-03 0,01195678 ! intracellular pH reduction GO:0051452 13 7 0,000 3,147E-03 0,01193822 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 3,147E-03 0,01191971 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 3,147E-03 0,01190126 ! organ growth GO:0035265 15 7 0,000 3,147E-03 0,01188286 ! nucleoside transport GO:0015858 11 7 0,000 3,147E-03 0,01186452 ! nucleoside salvage GO:0043174 11 7 0,000 3,147E-03 0,01184624 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 3,147E-03 0,01182802 ! male sex determination GO:0030238 15 7 0,000 3,147E-03 0,01180985 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 3,147E-03 0,01179174 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 3,147E-03 0,01177368 ! parturition GO:0007567 16 7 0,000 3,147E-03 0,01175568 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 3,147E-03 0,01173773 ! rRNA modification GO:0000154 14 7 0,000 3,147E-03 0,01171984 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 3,147E-03 0,011702 ! spindle checkpoint GO:0031577 16 7 0,000 3,147E-03 0,01168421 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 3,147E-03 0,01166648 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 3,147E-03 0,01164881 ! monocyte differentiation GO:0030224 16 7 0,000 3,147E-03 0,01163118 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 3,147E-03 0,01161361 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 3,147E-03 0,0115961 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 3,147E-03 0,01157863 ! hyaluronan metabolic process GO:0030212 9 7 0,000 3,147E-03 0,01156122 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 3,147E-03 0,01154386 ! anterograde axon cargo transport GO:0008089 18 7 0,000 3,147E-03 0,01152655 ! fibrinolysis GO:0042730 11 7 0,000 3,147E-03 0,0115093 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 3,147E-03 0,0114921 ! skeletal muscle contraction GO:0003009 8 7 0,000 3,147E-03 0,01147494 ! eating behavior GO:0042755 8 7 0,000 3,147E-03 0,01145784 ! B cell lineage commitment GO:0002326 21 7 0,000 3,147E-03 0,01144079 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 3,147E-03 0,01142379 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 3,147E-03 0,01140684 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 3,147E-03 0,01138994 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 3,147E-03 0,01137309 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 3,147E-03 0,0113563 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 3,147E-03 0,01133955 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 3,147E-03 0,01132285 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 3,147E-03 0,01130619 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 3,147E-03 0,01128959 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 3,147E-03 0,01127304 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 3,147E-03 0,01125653 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 3,147E-03 0,01124008 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 3,147E-03 0,01122367 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 3,147E-03 0,01120731 ! histone ubiquitination GO:0016574 9 7 0,000 3,147E-03 0,01119099 ! regulation of meiosis GO:0040020 12 7 0,000 3,147E-03 0,01117473 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 3,147E-03 0,01115851 ! T cell lineage commitment GO:0002360 16 7 0,000 3,147E-03 0,01114234 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 3,147E-03 0,01112621 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 3,147E-03 0,01111013 ! membrane to membrane docking GO:0022614 14 7 0,000 3,147E-03 0,0110941 ! transcription termination GO:0006353 14 7 0,000 3,147E-03 0,01107812 ! coenzyme A metabolic process GO:0015936 12 7 0,000 3,147E-03 0,01106218 ! anaphase GO:0051322 18 7 0,000 3,147E-03 0,01104628 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 3,147E-03 0,01103043 ! axonal fasciculation GO:0007413 19 7 0,000 3,147E-03 0,01101463 ! negative regulation of nuclear division GO:0051784 15 7 0,000 3,147E-03 0,01099887 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 3,147E-03 0,01098316 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 3,147E-03 0,01096749 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 3,147E-03 0,01095187 ! diuresis GO:0030146 12 7 0,000 3,147E-03 0,01093629 GO:0030147|natriuresis, ! thiamin metabolic process GO:0006772 7 7 0,000 3,147E-03 0,01092076 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 3,147E-03 0,01090527 ! antibiotic transport GO:0042891 9 7 0,000 3,147E-03 0,01088982 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 3,147E-03 0,01087442 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 3,147E-03 0,01085906 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 3,147E-03 0,01084374 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 3,147E-03 0,01082847 ! melanin biosynthetic process GO:0042438 10 7 0,000 3,147E-03 0,01081324 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 3,147E-03 0,01079805 ! dopamine biosynthetic process GO:0042416 18 7 0,000 3,147E-03 0,01078291 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 3,147E-03 0,0107678 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 3,147E-03 0,01075274 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 3,147E-03 0,01073773 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 3,147E-03 0,01072275 ! endosome to lysosome transport GO:0008333 12 7 0,000 3,147E-03 0,01070782 ! protein modification by small protein removal GO:0070646 19 7 0,000 3,147E-03 0,01069292 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 3,147E-03 0,01067807 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 3,147E-03 0,01066326 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 3,147E-03 0,01064849 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 3,147E-03 0,01063376 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 3,147E-03 0,01061908 ! muscle adaptation GO:0043500 13 7 0,000 3,147E-03 0,01060443 ! embryonic heart tube development GO:0035050 14 7 0,000 3,147E-03 0,01058982 ! retina homeostasis GO:0001895 12 7 0,000 3,147E-03 0,01057526 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 3,147E-03 0,01056073 ! protein amino acid prenylation GO:0018346 19 7 0,000 3,147E-03 0,01054624 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 3,147E-03 0,0105318 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 3,147E-03 0,01051739 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 3,596E-03 0,01200092 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 3,596E-03 0,01198455 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 3,596E-03 0,01196822 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 3,596E-03 0,01195194 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 3,596E-03 0,0119357 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 3,596E-03 0,0119195 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 3,596E-03 0,01190335 ! male meiosis GO:0007140 9 8 0,000 3,596E-03 0,01188725 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 3,596E-03 0,01187118 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 3,596E-03 0,01185516 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 3,596E-03 0,01183918 ! meiotic prophase I GO:0007128 14 8 0,000 3,596E-03 0,01182325 ! response to zinc ion GO:0010043 12 8 0,000 3,596E-03 0,01180736 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 3,596E-03 0,01179151 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 3,596E-03 0,0117757 ! oligopeptide transport GO:0006857 16 8 0,000 3,596E-03 0,01175994 ! actin-myosin filament sliding GO:0033275 13 8 0,000 3,596E-03 0,01174422 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 3,596E-03 0,01172854 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 3,596E-03 0,0117129 ! signal peptide processing GO:0006465 12 8 0,000 3,596E-03 0,0116973 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 3,596E-03 0,01168175 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 3,596E-03 0,01166623 ! macrophage chemotaxis GO:0048246 12 8 0,000 3,596E-03 0,01165076 ! succinate metabolic process GO:0006105 17 8 0,000 3,596E-03 0,01163533 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 3,596E-03 0,01161994 ! membrane hyperpolarization GO:0060081 11 8 0,000 3,596E-03 0,01160459 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 3,596E-03 0,01158928 ! estrogen metabolic process GO:0008210 17 8 0,000 3,596E-03 0,01157401 ! T-helper 1 type immune response GO:0042088 12 8 0,000 3,596E-03 0,01155878 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 3,596E-03 0,01154359 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 3,596E-03 0,01152844 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 3,596E-03 0,01151333 ! reflex GO:0060004 17 8 0,000 3,596E-03 0,01149827 ! endothelial cell differentiation GO:0045446 17 8 0,000 3,596E-03 0,01148323 ! glycerolipid catabolic process GO:0046503 14 8 0,000 3,596E-03 0,01146824 ! hemoglobin metabolic process GO:0020027 14 8 0,000 3,596E-03 0,01145329 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 3,596E-03 0,01143838 ! pigment granule organization GO:0048753 17 8 0,000 3,596E-03 0,0114235 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 3,596E-03 0,01140867 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 3,596E-03 0,01139387 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 3,596E-03 0,01137911 ! astrocyte differentiation GO:0048708 19 8 0,000 3,596E-03 0,01136439 ! histidine catabolic process GO:0006548 10 8 0,000 3,596E-03 0,01134971 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 3,596E-03 0,01133506 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 3,596E-03 0,01132046 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 3,596E-03 0,01130589 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 3,596E-03 0,01129136 ! regulation of pigmentation during development GO:0048070 25 8 0,000 3,596E-03 0,01127686 ! melanin metabolic process GO:0006582 17 8 0,000 3,596E-03 0,0112624 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 3,596E-03 0,01124798 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 3,596E-03 0,0112336 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 3,596E-03 0,01121925 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 3,596E-03 0,01120494 ! macrophage activation GO:0042116 13 8 0,000 3,596E-03 0,01119067 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 3,596E-03 0,01117643 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 3,596E-03 0,01116223 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 3,596E-03 0,01114806 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 3,596E-03 0,01113393 ! purine salvage GO:0043101 12 8 0,000 3,596E-03 0,01111984 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 3,596E-03 0,01110578 ! regulation of vascular permeability GO:0043114 12 8 0,000 3,596E-03 0,01109176 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 3,596E-03 0,01107777 ! osteoblast development GO:0002076 17 8 0,000 3,596E-03 0,01106382 ! positive regulation of vasodilation GO:0045909 14 8 0,000 3,596E-03 0,01104991 ! negative regulation of translational initiation GO:0045947 12 8 0,000 3,596E-03 0,01103602 ! Schwann cell differentiation GO:0014037 21 8 0,000 3,596E-03 0,01102218 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 3,596E-03 0,01100836 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 3,596E-03 0,01099459 ! response to UV-B GO:0010224 17 8 0,000 3,596E-03 0,01098084 ! protein targeting to vacuole GO:0006623 14 8 0,000 3,596E-03 0,01096713 ! protein retention in ER lumen GO:0006621 14 8 0,000 3,596E-03 0,01095346 ! intermediate filament organization GO:0045109 12 8 0,000 3,596E-03 0,01093982 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 3,596E-03 0,01092621 ! cellular extravasation GO:0045123 13 8 0,000 3,596E-03 0,01091264 ! cardiac muscle cell development GO:0055013 14 8 0,000 3,596E-03 0,0108991 ! response to antibiotic GO:0046677 11 8 0,000 3,596E-03 0,01088559 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 3,596E-03 0,01087212 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 3,596E-03 0,01085868 ! DNA topological change GO:0006265 12 8 0,000 3,596E-03 0,01084528 ! response to tropane GO:0014073 15 8 0,000 3,596E-03 0,0108319 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 3,596E-03 0,01081856 ! melanosome transport GO:0032402 13 8 0,000 3,596E-03 0,01080526 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 3,596E-03 0,01079198 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 3,596E-03 0,01077874 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 3,596E-03 0,01076553 ! mast cell activation GO:0045576 14 8 0,000 3,596E-03 0,01075236 ! multicellular organismal aging GO:0010259 20 8 0,000 3,596E-03 0,01073921 ! gas homeostasis GO:0033483 14 8 0,000 3,596E-03 0,0107261 ! dendrite morphogenesis GO:0048813 14 8 0,000 3,596E-03 0,01071302 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 3,596E-03 0,01069997 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 3,596E-03 0,01068695 ! nucleosome disassembly GO:0006337 14 8 0,000 3,596E-03 0,01067397 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 3,596E-03 0,01066101 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 3,596E-03 0,01064809 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 3,596E-03 0,0106352 ! establishment of chromosome localization GO:0051303 14 8 0,000 3,596E-03 0,01062234 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 3,596E-03 0,01060951 ! intracellular lipid transport GO:0032365 16 8 0,000 3,596E-03 0,01059671 ! response to tumor cell GO:0002347 16 8 0,000 3,596E-03 0,01058395 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 3,596E-03 0,01057121 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 3,596E-03 0,0105585 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 3,596E-03 0,01054583 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 3,596E-03 0,01053318 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 3,596E-03 0,01052057 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 3,596E-03 0,01050798 ! hormone catabolic process GO:0042447 17 8 0,000 3,596E-03 0,01049543 ! glycolipid catabolic process GO:0019377 16 8 0,000 3,596E-03 0,01048291 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 3,596E-03 0,01047041 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 3,596E-03 0,01045795 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 3,596E-03 0,01044551 ! positive regulation of glucose import GO:0046326 8 8 0,000 3,596E-03 0,01043311 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 3,596E-03 0,01042073 ! adult feeding behavior GO:0008343 10 8 0,000 3,596E-03 0,01040838 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 3,596E-03 0,01039606 ! ATP catabolic process GO:0006200 11 8 0,000 3,596E-03 0,01038378 ! blastocyst growth GO:0001832 19 8 0,000 3,596E-03 0,01037152 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 3,596E-03 0,01035929 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 3,596E-03 0,01034708 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 3,596E-03 0,01033491 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 3,596E-03 0,01032277 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 3,596E-03 0,01031065 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 3,596E-03 0,01029856 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 3,596E-03 0,0102865 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 3,596E-03 0,01027447 ! amino sugar catabolic process GO:0046348 11 8 0,000 3,596E-03 0,01026247 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 3,596E-03 0,0102505 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 3,596E-03 0,01023855 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 3,596E-03 0,01022663 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 3,596E-03 0,01021474 ! behavioral response to nicotine GO:0035095 12 8 0,000 3,596E-03 0,01020287 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 3,596E-03 0,01019104 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 3,596E-03 0,01017923 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 3,596E-03 0,01016745 ! NAD biosynthetic process GO:0009435 17 8 0,000 3,596E-03 0,01015569 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 3,596E-03 0,01014397 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 3,596E-03 0,01013227 ! axon extension GO:0048675 16 9 0,000 4,044E-03 0,01138327 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 4,044E-03 0,01137017 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 4,044E-03 0,0113571 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 4,044E-03 0,01134406 ! pentose-phosphate shunt GO:0006098 16 9 0,000 4,044E-03 0,01133105 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 4,044E-03 0,01131807 ! cell proliferation in forebrain GO:0021846 18 9 0,000 4,044E-03 0,01130512 ! neutral lipid catabolic process GO:0046461 14 9 0,000 4,044E-03 0,0112922 ! reproductive behavior GO:0019098 22 9 0,000 4,044E-03 0,01127931 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 4,044E-03 0,01126645 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 4,044E-03 0,01125362 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 4,044E-03 0,01124081 ! UTP metabolic process GO:0046051 10 9 0,000 4,044E-03 0,01122804 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 4,044E-03 0,01121529 ! induction of positive chemotaxis GO:0050930 17 9 0,000 4,044E-03 0,01120258 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 4,044E-03 0,01118989 ! artery development GO:0060840 25 9 0,000 4,044E-03 0,01117723 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 4,044E-03 0,0111646 ! regulation of glycolysis GO:0006110 20 9 0,000 4,044E-03 0,011152 ! cerebral cortex cell migration GO:0021795 18 9 0,000 4,044E-03 0,01113943 ! equilibrioception GO:0050957 20 9 0,000 4,044E-03 0,01112689 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 4,044E-03 0,01111437 ! chemosensory behavior GO:0007635 21 9 0,000 4,044E-03 0,01110188 ! microtubule bundle formation GO:0001578 22 9 0,000 4,044E-03 0,01108942 ! middle ear morphogenesis GO:0042474 14 9 0,000 4,044E-03 0,01107699 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 4,044E-03 0,01106458 ! leukocyte degranulation GO:0043299 16 9 0,000 4,044E-03 0,01105221 ! ganglioside metabolic process GO:0001573 22 9 0,000 4,044E-03 0,01103986 ! negative regulation of endocytosis GO:0045806 12 9 0,000 4,044E-03 0,01102754 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 4,044E-03 0,01101524 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 4,044E-03 0,01100298 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 4,044E-03 0,01099074 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 4,044E-03 0,01097853 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 4,044E-03 0,01096634 ! protein targeting to ER GO:0045047 25 9 0,000 4,044E-03 0,01095418 ! ceramide biosynthetic process GO:0046513 20 9 0,000 4,044E-03 0,01094205 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 4,044E-03 0,01092995 ! T cell selection GO:0045058 27 9 0,000 4,044E-03 0,01091787 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 4,044E-03 0,01090582 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 4,044E-03 0,0108938 ! glycine catabolic process GO:0006546 15 9 0,000 4,044E-03 0,0108818 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 4,044E-03 0,01086983 ! endosome organization GO:0007032 20 9 0,000 4,044E-03 0,01085788 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 4,044E-03 0,01084597 ! regulation of type I interferon production GO:0032479 12 9 0,000 4,044E-03 0,01083407 ! mannose metabolic process GO:0006013 13 9 0,000 4,044E-03 0,01082221 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 4,044E-03 0,01081037 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 4,044E-03 0,01079855 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 4,044E-03 0,01078676 ! Rac protein signal transduction GO:0016601 20 9 0,000 4,044E-03 0,010775 ! receptor clustering GO:0043113 20 9 0,000 4,044E-03 0,01076326 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 4,044E-03 0,01075155 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 4,044E-03 0,01073986 ! retinol metabolic process GO:0042572 20 9 0,000 4,044E-03 0,0107282 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 4,044E-03 0,01071657 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 4,044E-03 0,01070496 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 4,044E-03 0,01069337 ! macrophage differentiation GO:0030225 15 9 0,000 4,044E-03 0,01068181 ! oligodendrocyte development GO:0014003 11 9 0,000 4,044E-03 0,01067027 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 4,044E-03 0,01065876 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 4,044E-03 0,01064728 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 4,044E-03 0,01063582 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 4,044E-03 0,01062438 ! response to amine stimulus GO:0014075 13 9 0,000 4,044E-03 0,01061297 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 4,044E-03 0,01060158 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 4,044E-03 0,01059022 ! erythrocyte development GO:0048821 17 9 0,000 4,044E-03 0,01057888 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 4,044E-03 0,01056757 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 4,044E-03 0,01055628 ! renal water homeostasis GO:0003091 15 9 0,000 4,044E-03 0,01054501 ! postreplication repair GO:0006301 25 9 0,000 4,044E-03 0,01053377 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 4,044E-03 0,01052255 ! icosanoid secretion GO:0032309 15 9 0,000 4,044E-03 0,01051136 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 4,044E-03 0,01050019 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 4,044E-03 0,01048904 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 4,044E-03 0,01047792 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 4,044E-03 0,01046682 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 4,044E-03 0,01045574 ! sterol catabolic process GO:0016127 14 9 0,000 4,044E-03 0,01044469 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 4,044E-03 0,01043366 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 4,044E-03 0,01042265 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 4,044E-03 0,01041167 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 4,044E-03 0,01040071 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 4,044E-03 0,01038977 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 4,044E-03 0,01037886 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 4,044E-03 0,01036797 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 4,044E-03 0,0103571 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 4,044E-03 0,01034626 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 4,044E-03 0,01033543 ! regulation of synaptogenesis GO:0051963 15 9 0,000 4,044E-03 0,01032463 ! purine base metabolic process GO:0006144 25 9 0,000 4,044E-03 0,01031386 ! pigment granule transport GO:0051904 17 9 0,000 4,044E-03 0,0103031 ! regulation of telomere maintenance GO:0032204 17 9 0,000 4,044E-03 0,01029237 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 4,044E-03 0,01028166 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 4,044E-03 0,01027097 ! regulation of muscle adaptation GO:0043502 14 9 0,000 4,044E-03 0,01026031 ! regulation of amino acid transport GO:0051955 12 9 0,000 4,044E-03 0,01024966 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 4,044E-03 0,01023904 ! mitochondrion localization GO:0051646 18 9 0,000 4,044E-03 0,01022844 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 4,493E-03 0,01135079 ! regulation of developmental growth GO:0048638 16 10 0,000 4,493E-03 0,01133906 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 4,493E-03 0,01132736 ! autophagic vacuole formation GO:0000045 17 10 0,000 4,493E-03 0,01131568 ! negative regulation of blood pressure GO:0045776 26 10 0,000 4,493E-03 0,01130403 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 4,493E-03 0,0112924 ! associative learning GO:0008306 21 10 0,000 4,493E-03 0,01128079 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 4,493E-03 0,01126921 ! phosphate transport GO:0006817 24 10 0,000 4,493E-03 0,01125765 ! cell volume homeostasis GO:0006884 17 10 0,000 4,493E-03 0,01124612 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 4,493E-03 0,01123461 ! CTP metabolic process GO:0046036 11 10 0,000 4,493E-03 0,01122312 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 4,493E-03 0,01121166 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 4,493E-03 0,01120022 ! GTP metabolic process GO:0046039 11 10 0,000 4,493E-03 0,0111888 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 4,493E-03 0,0111774 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 4,493E-03 0,01116603 ! social behavior GO:0035176 29 10 0,000 4,493E-03 0,01115469 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 4,493E-03 0,01114336 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 4,493E-03 0,01113206 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 4,493E-03 0,01112078 ! androgen metabolic process GO:0008209 17 10 0,000 4,493E-03 0,01110953 ! phospholipid efflux GO:0033700 19 10 0,000 4,493E-03 0,01109829 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 4,493E-03 0,01108708 ! bile acid and bile salt transport GO:0015721 15 10 0,000 4,493E-03 0,01107589 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 4,493E-03 0,01106473 ! positive regulation of heart contraction GO:0045823 17 10 0,000 4,493E-03 0,01105359 ! lung alveolus development GO:0048286 26 10 0,000 4,493E-03 0,01104247 ! pathogenesis GO:0009405 17 10 0,000 4,493E-03 0,01103137 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 4,493E-03 0,01102029 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 4,493E-03 0,01100924 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 4,493E-03 0,01099821 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 4,493E-03 0,0109872 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 4,493E-03 0,01097621 ! arginine catabolic process GO:0006527 17 10 0,000 4,493E-03 0,01096525 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 4,493E-03 0,0109543 ! proline metabolic process GO:0006560 13 10 0,000 4,493E-03 0,01094338 ! glucan biosynthetic process GO:0009250 14 10 0,000 4,493E-03 0,01093248 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 4,493E-03 0,0109216 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 4,493E-03 0,01091075 ! V(D)J recombination GO:0033151 34 10 0,000 4,493E-03 0,01089991 ! reverse cholesterol transport GO:0043691 19 10 0,000 4,493E-03 0,0108891 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 4,493E-03 0,01087831 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 19 10 0,000 4,493E-03 0,01086754 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 4,493E-03 0,01085679 ! regulation of sodium ion transport GO:0002028 26 10 0,000 4,493E-03 0,01084606 ! multicellular organism growth GO:0035264 19 10 0,000 4,493E-03 0,01083535 ! phagocytosis, engulfment GO:0006911 33 10 0,000 4,493E-03 0,01082467 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 4,493E-03 0,010814 ! ruffle organization GO:0031529 17 10 0,000 4,493E-03 0,01080336 ! epithelial cell development GO:0002064 21 10 0,000 4,493E-03 0,01079273 ! lens development in camera-type eye GO:0002088 17 10 0,000 4,493E-03 0,01078213 ! retinoic acid metabolic process GO:0042573 14 10 0,000 4,493E-03 0,01077155 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 4,493E-03 0,01076099 ! positive regulation of translational initiation GO:0045948 12 10 0,000 4,493E-03 0,01075045 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 4,493E-03 0,01073993 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 4,493E-03 0,01072943 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 4,493E-03 0,01071896 ! motor axon guidance GO:0008045 22 10 0,000 4,493E-03 0,0107085 ! copper ion homeostasis GO:0055070 13 10 0,000 4,493E-03 0,01069806 ! regulation of bone resorption GO:0045124 25 10 0,000 4,493E-03 0,01068764 ! protein heterooligomerization GO:0051291 17 10 0,000 4,493E-03 0,01067725 ! regulation of gliogenesis GO:0014013 23 10 0,000 4,493E-03 0,01066687 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 4,493E-03 0,01065652 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 4,493E-03 0,01064618 ! segment specification GO:0007379 15 10 0,000 4,493E-03 0,01063586 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 4,493E-03 0,01062557 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 4,493E-03 0,01061529 ! blastoderm segmentation GO:0007350 19 10 0,000 4,493E-03 0,01060504 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 4,493E-03 0,0105948 ! response to dsRNA GO:0043331 23 10 0,000 4,493E-03 0,01058458 ! DNA ligation GO:0006266 18 10 0,000 4,493E-03 0,01057438 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 4,493E-03 0,01056421 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 4,493E-03 0,01055405 ! melanosome localization GO:0032400 16 10 0,000 4,493E-03 0,01054391 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 4,493E-03 0,01053379 ! regulation of B cell differentiation GO:0045577 24 10 0,000 4,493E-03 0,01052369 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 4,493E-03 0,01051361 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 4,493E-03 0,01050355 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 4,493E-03 0,01049351 ! induction of an organ GO:0001759 17 10 0,000 4,493E-03 0,01048349 ! leukocyte activation during immune response GO:0002366 15 10 0,000 4,493E-03 0,01047348 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 4,493E-03 0,0104635 ! protein sumoylation GO:0016925 17 10 0,000 4,493E-03 0,01045353 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 4,493E-03 0,01044359 ! hindbrain morphogenesis GO:0021575 19 10 0,000 4,493E-03 0,01043366 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 4,493E-03 0,01042375 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 4,493E-03 0,01041386 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 4,493E-03 0,01040399 ! salivary gland development GO:0007431 28 10 0,000 4,493E-03 0,01039414 ! ubiquinone metabolic process GO:0006743 17 10 0,000 4,493E-03 0,01038431 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 4,493E-03 0,01037449 ! midbrain development GO:0030901 14 10 0,000 4,493E-03 0,01036469 ! musculoskeletal movement GO:0050881 16 10 0,000 4,493E-03 0,01035492 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 4,493E-03 0,01034516 ! methionine biosynthetic process GO:0009086 21 10 0,000 4,493E-03 0,01033542 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 4,493E-03 0,01032569 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 4,493E-03 0,01031599 ! quaternary ammonium group transport GO:0015697 22 10 0,000 4,493E-03 0,0103063 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 4,493E-03 0,01029663 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 4,493E-03 0,01028698 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 4,493E-03 0,01027735 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 4,493E-03 0,01026774 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 4,493E-03 0,01025814 ! establishment of pigment granule localization GO:0051905 18 10 0,000 4,493E-03 0,01024856 ! blastocyst formation GO:0001825 18 10 0,000 4,493E-03 0,010239 ! regulation of fibrinolysis GO:0051917 20 10 0,000 4,493E-03 0,01022946 ! cerebellar cortex development GO:0021695 16 10 0,000 4,493E-03 0,01021994 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 4,493E-03 0,01021043 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 4,493E-03 0,01020094 ! response to nicotine GO:0035094 20 10 0,000 4,493E-03 0,01019147 ! negative regulation of immune effector process GO:0002698 23 10 0,000 4,493E-03 0,01018201 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 4,493E-03 0,01017258 ! negative regulation of muscle development GO:0048635 27 11 0,000 4,941E-03 0,01117712 ! respiratory burst GO:0045730 17 11 0,000 4,941E-03 0,01116678 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 4,941E-03 0,01115646 ! neuron fate specification GO:0048665 18 11 0,000 4,941E-03 0,01114616 ! telencephalon cell migration GO:0022029 23 11 0,000 4,941E-03 0,01113587 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 4,941E-03 0,01112561 ! thyroid gland development GO:0030878 26 11 0,000 4,941E-03 0,01111536 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 4,941E-03 0,01110514 ! synapsis GO:0007129 14 11 0,000 4,941E-03 0,01109493 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 4,941E-03 0,01108474 ! Golgi vesicle budding GO:0048194 26 11 0,000 4,941E-03 0,01107457 ! response to pain GO:0048265 27 11 0,000 4,941E-03 0,01106442 ! detection of mechanical stimulus GO:0050982 22 11 0,000 4,941E-03 0,01105429 ! blood vessel remodeling GO:0001974 30 11 0,000 4,941E-03 0,01104418 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 4,941E-03 0,01103408 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 4,941E-03 0,01102401 ! bone resorption GO:0045453 16 11 0,000 4,941E-03 0,01101395 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 4,941E-03 0,01100391 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 4,941E-03 0,01099389 ! negative regulation of proteolysis GO:0045861 25 11 0,000 4,941E-03 0,01098388 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 4,941E-03 0,0109739 ! melanocyte differentiation GO:0030318 20 11 0,000 4,941E-03 0,01096393 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 4,941E-03 0,01095398 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 4,941E-03 0,01094405 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 4,941E-03 0,01093414 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 4,941E-03 0,01092424 ! regulation of intracellular pH GO:0051453 21 11 0,000 4,941E-03 0,01091436 ! substrate-bound cell migration GO:0006929 14 11 0,000 4,941E-03 0,0109045 ! adult heart development GO:0007512 16 11 0,000 4,941E-03 0,01089466 ! chondrocyte differentiation GO:0002062 27 11 0,000 4,941E-03 0,01088484 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 4,941E-03 0,01087503 ! macroautophagy GO:0016236 19 11 0,000 4,941E-03 0,01086524 ! temperature homeostasis GO:0001659 18 11 0,000 4,941E-03 0,01085547 ! behavioral fear response GO:0001662 27 11 0,000 4,941E-03 0,01084572 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 4,941E-03 0,01083598 ! negative regulation of ossification GO:0030279 27 11 0,000 4,941E-03 0,01082627 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 4,941E-03 0,01081656 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 4,941E-03 0,01080688 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 4,941E-03 0,01079721 ! alpha-beta T cell activation GO:0046631 26 11 0,000 4,941E-03 0,01078757 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 4,941E-03 0,01077793 ! regulation of organ growth GO:0046620 14 11 0,000 4,941E-03 0,01076832 ! pigment granule localization GO:0051875 20 11 0,000 4,941E-03 0,01075872 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 4,941E-03 0,01074914 ! vasoconstriction GO:0042310 20 11 0,000 4,941E-03 0,01073958 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 4,941E-03 0,01073003 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 4,941E-03 0,0107205 ! embryonic axis specification GO:0000578 19 11 0,000 4,941E-03 0,01071099 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 4,941E-03 0,01070149 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 4,941E-03 0,01069202 ! nitric oxide metabolic process GO:0046209 17 11 0,000 4,941E-03 0,01068255 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 4,941E-03 0,01067311 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 4,941E-03 0,01066368 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 4,941E-03 0,01065427 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 4,941E-03 0,01064487 ! prophase GO:0051324 17 11 0,000 4,941E-03 0,01063549 ! neuroblast proliferation GO:0007405 25 11 0,000 4,941E-03 0,01062613 ! nucleosome positioning GO:0016584 15 11 0,000 4,941E-03 0,01061679 ! regulation of isotype switching GO:0045191 24 11 0,000 4,941E-03 0,01060746 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 4,941E-03 0,01059814 ! negative regulation of neurological system process GO:0031645 21 11 0,000 4,941E-03 0,01058885 ! apical protein localization GO:0045176 18 11 0,000 4,941E-03 0,01057957 ! acid secretion GO:0046717 20 11 0,000 4,941E-03 0,0105703 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 4,941E-03 0,01056106 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 4,941E-03 0,01055182 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 4,941E-03 0,01054261 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 4,941E-03 0,01053341 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 4,941E-03 0,01052422 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 4,941E-03 0,01051506 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 4,941E-03 0,01050591 ! cholesterol efflux GO:0033344 21 11 0,000 4,941E-03 0,01049677 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 4,941E-03 0,01048765 ! oocyte development GO:0048599 20 11 0,000 4,941E-03 0,01047855 ! negative regulation of glucose import GO:0046325 18 11 0,000 4,941E-03 0,01046946 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 4,941E-03 0,01046039 ! embryonic gut development GO:0048566 19 11 0,000 4,941E-03 0,01045133 ! regulation of organic acid transport GO:0032890 19 11 0,000 4,941E-03 0,01044229 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 4,941E-03 0,01043326 ! activation of innate immune response GO:0002218 16 11 0,000 4,941E-03 0,01042425 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 36 11 0,000 4,941E-03 0,01041526 ! lysogeny GO:0030069 22 11 0,000 4,941E-03 0,01040628 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 4,941E-03 0,01039732 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 4,941E-03 0,01038837 ! sequestering of metal ion GO:0051238 15 11 0,000 4,941E-03 0,01037944 ! regulation of embryonic development GO:0045995 35 11 0,000 4,941E-03 0,01037052 ! nucleus localization GO:0051647 22 11 0,000 4,941E-03 0,01036162 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 5,389E-03 0,01129151 ! positive regulation of blood pressure GO:0045777 18 12 0,000 5,389E-03 0,01128183 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 5,389E-03 0,01127217 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 5,389E-03 0,01126253 ! virus-host interaction GO:0019048 30 12 0,000 5,389E-03 0,0112529 ! regulation of B cell proliferation GO:0030888 22 12 0,000 5,389E-03 0,01124329 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 5,389E-03 0,0112337 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 5,389E-03 0,01122412 ! protein complex disassembly GO:0043241 28 12 0,000 5,389E-03 0,01121456 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 5,389E-03 0,01120502 ! regulation of cell projection assembly GO:0060491 33 12 0,000 5,389E-03 0,01119549 ! hippocampus development GO:0021766 29 12 0,000 5,389E-03 0,01118598 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 5,389E-03 0,01117648 ! cytokine biosynthetic process GO:0042089 23 12 0,000 5,389E-03 0,011167 ! T cell proliferation GO:0042098 32 12 0,000 5,389E-03 0,01115754 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 5,389E-03 0,01114809 ! regulation of exit from mitosis GO:0007096 19 12 0,000 5,389E-03 0,01113866 ! ventral spinal cord development GO:0021517 25 12 0,000 5,389E-03 0,01112925 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 5,389E-03 0,01111985 ! drug transport GO:0015893 16 12 0,000 5,389E-03 0,01111046 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 5,389E-03 0,01110109 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 5,389E-03 0,01109174 ! tyrosine metabolic process GO:0006570 19 12 0,000 5,389E-03 0,01108241 ! polyamine metabolic process GO:0006595 18 12 0,000 5,389E-03 0,01107309 ! focal adhesion formation GO:0048041 37 12 0,000 5,389E-03 0,01106378 ! mitotic spindle organization GO:0007052 23 12 0,000 5,389E-03 0,01105449 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 5,389E-03 0,01104522 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 5,389E-03 0,01103596 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 5,389E-03 0,01102672 ! lipid digestion GO:0044241 21 12 0,000 5,389E-03 0,01101749 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 5,389E-03 0,01100828 ! entry into host cell GO:0030260 34 12 0,000 5,389E-03 0,01099908 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 5,389E-03 0,0109899 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 5,389E-03 0,01098073 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 5,389E-03 0,01097158 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 5,389E-03 0,01096245 ! protein targeting to peroxisome GO:0006625 27 12 0,000 5,389E-03 0,01095333 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 5,389E-03 0,01094422 ! regulation of phagocytosis GO:0050764 17 12 0,000 5,389E-03 0,01093513 ! snRNA metabolic process GO:0016073 30 12 0,000 5,389E-03 0,01092606 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 5,389E-03 0,010917 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 5,389E-03 0,01090795 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 5,389E-03 0,01089892 ! cranial nerve development GO:0021545 23 12 0,000 5,389E-03 0,01088991 ! fucose catabolic process GO:0019317 25 12 0,000 5,389E-03 0,01088091 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 5,389E-03 0,01087192 ! histone acetylation GO:0016573 27 12 0,000 5,389E-03 0,01086295 ! mRNA polyadenylation GO:0006378 24 12 0,000 5,389E-03 0,010854 ! autonomic nervous system development GO:0048483 24 12 0,000 5,389E-03 0,01084506 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 5,389E-03 0,01083613 ! zymogen activation GO:0031638 18 12 0,000 5,389E-03 0,01082722 ! peptidyl-lysine modification GO:0018205 21 12 0,000 5,389E-03 0,01081832 ! T cell homeostasis GO:0043029 28 12 0,000 5,389E-03 0,01080944 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 5,389E-03 0,01080057 ! glutathione biosynthetic process GO:0006750 15 12 0,000 5,389E-03 0,01079172 ! regulation of leukocyte migration GO:0002685 29 12 0,000 5,389E-03 0,01078288 ! oocyte differentiation GO:0009994 21 12 0,000 5,389E-03 0,01077406 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 5,389E-03 0,01076525 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 5,389E-03 0,01075645 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 5,389E-03 0,01074767 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 5,389E-03 0,01073891 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 5,389E-03 0,01073015 ! defense response to fungus GO:0050832 15 12 0,000 5,389E-03 0,01072142 ! developmental induction GO:0031128 22 12 0,000 5,389E-03 0,01071269 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 5,389E-03 0,01070398 ! lamellipodium assembly GO:0030032 24 12 0,000 5,389E-03 0,01069529 ! response to cold GO:0009409 17 12 0,000 5,389E-03 0,01068661 ! establishment of cell polarity GO:0030010 21 12 0,000 5,389E-03 0,01067794 ! regulation of synapse organization GO:0050807 18 12 0,000 5,389E-03 0,01066929 ! localization within membrane GO:0051668 26 12 0,000 5,389E-03 0,01066065 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 5,837E-03 0,01153726 ! cGMP metabolic process GO:0046068 18 13 0,000 5,837E-03 0,01152793 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 5,837E-03 0,01151862 ! regulation of chemokine production GO:0032642 18 13 0,000 5,837E-03 0,01150932 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 5,837E-03 0,01150004 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 5,837E-03 0,01149077 ! peroxisomal transport GO:0043574 28 13 0,000 5,837E-03 0,01148152 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 5,837E-03 0,01147228 ! cartilage condensation GO:0001502 22 13 0,000 5,837E-03 0,01146306 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 5,837E-03 0,01145385 ! organelle fusion GO:0048284 36 13 0,000 5,837E-03 0,01144466 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 5,837E-03 0,01143548 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 5,837E-03 0,01142632 ! pseudouridine synthesis GO:0001522 19 13 0,000 5,837E-03 0,01141717 ! endocrine pancreas development GO:0031018 25 13 0,000 5,837E-03 0,01140804 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 5,837E-03 0,01139892 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 5,837E-03 0,01138982 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 5,837E-03 0,01138073 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 5,837E-03 0,01137165 ! methionine metabolic process GO:0006555 31 13 0,000 5,837E-03 0,01136259 ! plasma membrane organization GO:0007009 27 13 0,000 5,837E-03 0,01135354 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 5,837E-03 0,01134451 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 5,837E-03 0,01133549 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 5,837E-03 0,01132649 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 5,837E-03 0,0113175 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 5,837E-03 0,01130852 ! cytokine metabolic process GO:0042107 24 13 0,000 5,837E-03 0,01129956 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 5,837E-03 0,01129062 ! exocrine system development GO:0035272 34 13 0,000 5,837E-03 0,01128168 ! asymmetric protein localization GO:0008105 24 13 0,000 5,837E-03 0,01127277 ! membrane protein proteolysis GO:0033619 33 13 0,000 5,837E-03 0,01126386 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 5,837E-03 0,01125497 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 5,837E-03 0,0112461 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 5,837E-03 0,01123723 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 5,837E-03 0,01122838 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 5,837E-03 0,01121955 ! protein homotetramerization GO:0051289 24 13 0,000 5,837E-03 0,01121073 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 5,837E-03 0,01120192 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 5,837E-03 0,01119313 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 5,837E-03 0,01118435 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 5,837E-03 0,01117559 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 5,837E-03 0,01116684 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 5,837E-03 0,0111581 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 5,837E-03 0,01114937 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 5,837E-03 0,01114066 ! histone methylation GO:0016571 29 13 0,000 5,837E-03 0,01113197 ! chromatin silencing GO:0006342 29 13 0,000 5,837E-03 0,01112328 ! gland morphogenesis GO:0022612 31 13 0,000 5,837E-03 0,01111461 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 5,837E-03 0,01110596 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 5,837E-03 0,01109731 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 5,837E-03 0,01108868 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 5,837E-03 0,01108007 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 5,837E-03 0,01107147 ! spleen development GO:0048536 24 13 0,000 5,837E-03 0,01106288 ! regulation of mRNA stability GO:0043488 32 13 0,000 5,837E-03 0,0110543 ! biogenic amine catabolic process GO:0042402 24 13 0,000 5,837E-03 0,01104574 ! anterior/posterior axis specification GO:0009948 22 13 0,000 5,837E-03 0,01103719 ! regulation of RNA splicing GO:0043484 22 13 0,000 5,837E-03 0,01102865 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 5,837E-03 0,01102013 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 5,837E-03 0,01101162 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 5,837E-03 0,01100312 ! mRNA 3'-end processing GO:0031124 25 13 0,000 5,837E-03 0,01099464 ! insulin secretion GO:0030073 24 13 0,000 5,837E-03 0,01098617 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 5,837E-03 0,01097771 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 5,837E-03 0,01096927 ! acrosome reaction GO:0007340 19 13 0,000 5,837E-03 0,01096084 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 5,837E-03 0,01095242 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 5,837E-03 0,01094401 ! rRNA transcription GO:0009303 28 14 0,000 6,285E-03 0,01177434 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 6,285E-03 0,01176532 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 6,285E-03 0,01175631 ! water transport GO:0006833 21 14 0,000 6,285E-03 0,01174731 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 6,285E-03 0,01173833 ! non-recombinational repair GO:0000726 29 14 0,000 6,285E-03 0,01172936 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 6,285E-03 0,01172041 ! retina development in camera-type eye GO:0060041 28 14 0,000 6,285E-03 0,01171147 ! RNA polyadenylation GO:0043631 32 14 0,000 6,285E-03 0,01170254 ! lipid localization GO:0010876 32 14 0,000 6,285E-03 0,01169363 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 6,285E-03 0,01168473 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 6,285E-03 0,01167585 ! regulated secretory pathway GO:0045055 24 14 0,000 6,285E-03 0,01166697 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 6,285E-03 0,01165811 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 6,285E-03 0,01164927 ! arginine metabolic process GO:0006525 21 14 0,000 6,285E-03 0,01164044 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 6,285E-03 0,01163162 ! cell-cell junction assembly GO:0007043 32 14 0,000 6,285E-03 0,01162281 ! regulation of heart rate GO:0002027 25 14 0,000 6,285E-03 0,01161402 ! fear response GO:0042596 34 14 0,000 6,285E-03 0,01160524 ! organic alcohol transport GO:0015850 29 14 0,000 6,285E-03 0,01159648 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 6,285E-03 0,01158773 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 6,285E-03 0,01157899 ! neutral amino acid transport GO:0015804 28 14 0,000 6,285E-03 0,01157026 ! bone mineralization GO:0030282 18 14 0,000 6,285E-03 0,01156155 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 6,285E-03 0,01155285 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 6,285E-03 0,01154416 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 6,285E-03 0,01153549 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 6,285E-03 0,01152683 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 6,285E-03 0,01151818 ! regulation of cellular pH GO:0030641 27 14 0,000 6,285E-03 0,01150955 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 6,285E-03 0,01150093 ! ribosome assembly GO:0042255 18 14 0,000 6,285E-03 0,01149232 ! cerebellum development GO:0021549 23 14 0,000 6,285E-03 0,01148372 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 6,285E-03 0,01147514 ! negative regulation of protein secretion GO:0050709 30 14 0,000 6,285E-03 0,01146657 ! response to gamma radiation GO:0010332 30 14 0,000 6,285E-03 0,01145801 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 6,285E-03 0,01144947 ! NADP metabolic process GO:0006739 24 14 0,000 6,285E-03 0,01144094 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 6,285E-03 0,01143242 ! oxygen transport GO:0015671 22 14 0,000 6,285E-03 0,01142391 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 6,285E-03 0,01141542 ! male genitalia development GO:0030539 26 14 0,000 6,285E-03 0,01140694 ! regulation of RNA stability GO:0043487 33 14 0,000 6,285E-03 0,01139847 ! regulation of axon extension GO:0030516 43 14 0,000 6,285E-03 0,01139001 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 6,285E-03 0,01138157 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 6,285E-03 0,01137314 ! lactation GO:0007595 30 15 0,000 6,732E-03 0,01217392 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 6,732E-03 0,01216491 ! reproductive cellular process GO:0048610 22 15 0,000 6,732E-03 0,01215592 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 6,732E-03 0,01214694 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 6,732E-03 0,01213798 ! superoxide anion generation GO:0042554 22 15 0,000 6,732E-03 0,01212903 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 6,732E-03 0,01212009 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 6,732E-03 0,01211117 ! phospholipid catabolic process GO:0009395 27 15 0,000 6,732E-03 0,01210225 ! copper ion transport GO:0006825 22 15 0,000 6,732E-03 0,01209336 ! cardiac muscle contraction GO:0060048 28 15 0,000 6,732E-03 0,01208447 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 6,732E-03 0,0120756 ! sulfate transport GO:0008272 27 15 0,000 6,732E-03 0,01206674 ! response to cAMP GO:0051591 25 15 0,000 6,732E-03 0,01205789 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 6,732E-03 0,01204906 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 6,732E-03 0,01204024 ! regulation of mRNA processing GO:0050684 26 15 0,000 6,732E-03 0,01203143 ! response to hexose stimulus GO:0009746 25 15 0,000 6,732E-03 0,01202263 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 6,732E-03 0,01201385 ! glycoprotein catabolic process GO:0006516 33 15 0,000 6,732E-03 0,01200508 ! vesicle coating GO:0006901 38 15 0,000 6,732E-03 0,01199633 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 6,732E-03 0,01198758 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 6,732E-03 0,01197885 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 6,732E-03 0,01197013 ! regulation of exocytosis GO:0017157 26 15 0,000 6,732E-03 0,01196143 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 6,732E-03 0,01195273 ! G1/S transition checkpoint GO:0031575 37 15 0,000 6,732E-03 0,01194405 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 6,732E-03 0,01193539 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 6,732E-03 0,01192673 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 6,732E-03 0,01191809 ! regulation of vasodilation GO:0042312 27 15 0,000 6,732E-03 0,01190946 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 6,732E-03 0,01190084 ! histone deacetylation GO:0016575 24 15 0,000 6,732E-03 0,01189224 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 6,732E-03 0,01188364 ! water homeostasis GO:0030104 28 15 0,000 6,732E-03 0,01187506 ! cofactor transport GO:0051181 30 15 0,000 6,732E-03 0,0118665 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 6,732E-03 0,01185794 ! muscle maintenance GO:0046716 26 15 0,000 6,732E-03 0,0118494 ! protein-chromophore linkage GO:0018298 25 15 0,000 6,732E-03 0,01184087 ! intestinal absorption GO:0050892 31 15 0,000 6,732E-03 0,01183235 ! dopamine metabolic process GO:0042417 35 15 0,000 6,732E-03 0,01182384 ! cAMP biosynthetic process GO:0006171 25 15 0,000 6,732E-03 0,01181535 ! heme biosynthetic process GO:0006783 33 15 0,000 6,732E-03 0,01180687 ! cell killing GO:0001906 32 15 0,000 6,732E-03 0,0117984 ! lymphocyte homeostasis GO:0002260 33 15 0,000 6,732E-03 0,01178994 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 6,732E-03 0,01178149 ! L-fucose metabolic process GO:0042354 33 15 0,000 6,732E-03 0,01177306 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 6,732E-03 0,01176464 ! actin filament polymerization GO:0030041 27 15 0,000 6,732E-03 0,01175623 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 6,732E-03 0,01174783 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 7,18E-03 0,01251943 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 7,18E-03 0,01251051 ! dicarboxylic acid transport GO:0006835 47 16 0,000 7,18E-03 0,01250159 ! bone remodeling GO:0046849 28 16 0,000 7,18E-03 0,01249268 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 7,18E-03 0,01248379 ! heterophilic cell adhesion GO:0007157 43 16 0,000 7,18E-03 0,01247491 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 7,18E-03 0,01246605 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 7,18E-03 0,01245719 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 7,18E-03 0,01244835 ! positive regulation of ion transport GO:0043270 23 16 0,000 7,18E-03 0,01243952 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 7,18E-03 0,01243071 ! startle response GO:0001964 28 16 0,000 7,18E-03 0,0124219 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 7,18E-03 0,01241311 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 7,18E-03 0,01240433 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 7,18E-03 0,01239557 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 7,18E-03 0,01238681 ! protein polyubiquitination GO:0000209 41 16 0,000 7,18E-03 0,01237807 ! glutamate metabolic process GO:0006536 25 16 0,000 7,18E-03 0,01236934 ! pituitary gland development GO:0021983 30 16 0,000 7,18E-03 0,01236063 ! response to osmotic stress GO:0006970 27 16 0,000 7,18E-03 0,01235192 ! lysosomal transport GO:0007041 31 16 0,000 7,18E-03 0,01234323 ! fructose metabolic process GO:0006000 25 16 0,000 7,18E-03 0,01233455 ! L-amino acid transport GO:0015807 33 16 0,000 7,18E-03 0,01232588 ! stem cell development GO:0048864 46 16 0,000 7,18E-03 0,01231722 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 7,18E-03 0,01230858 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 7,18E-03 0,01229995 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 7,18E-03 0,01229133 ! negative regulation of immune response GO:0050777 38 16 0,000 7,18E-03 0,01228272 ! axon cargo transport GO:0008088 46 16 0,000 7,18E-03 0,01227413 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 7,18E-03 0,01226554 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 7,18E-03 0,01225697 ! DNA replication initiation GO:0006270 28 16 0,000 7,18E-03 0,01224841 ! neuron recognition GO:0008038 40 16 0,000 7,18E-03 0,01223987 ! mRNA splice site selection GO:0006376 44 16 0,000 7,18E-03 0,01223133 ! tissue regeneration GO:0042246 27 16 0,000 7,18E-03 0,01222281 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 7,18E-03 0,0122143 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 7,18E-03 0,0122058 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 7,18E-03 0,01219731 ! biomineral formation GO:0031214 22 16 0,000 7,18E-03 0,01218883 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 7,18E-03 0,01218037 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 7,18E-03 0,01217191 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 7,18E-03 0,01216347 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 7,18E-03 0,01215504 ! regulation of ATPase activity GO:0043462 26 16 0,000 7,18E-03 0,01214663 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 7,18E-03 0,01213822 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 7,18E-03 0,01212983 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 7,18E-03 0,01212144 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 7,18E-03 0,01211307 ! peptide hormone processing GO:0016486 27 16 0,000 7,18E-03 0,01210471 ! positive regulation of cell killing GO:0031343 36 17 0,000 7,627E-03 0,01284968 ! metencephalon development GO:0022037 32 17 0,000 7,627E-03 0,01284082 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 7,627E-03 0,01283198 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 7,627E-03 0,01282315 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 7,627E-03 0,01281433 ! signal complex assembly GO:0007172 47 17 0,000 7,627E-03 0,01280552 ! filopodium assembly GO:0046847 42 17 0,000 7,627E-03 0,01279673 ! endothelial cell migration GO:0043542 31 17 0,000 7,627E-03 0,01278794 ! gene silencing by RNA GO:0031047 38 17 0,000 7,627E-03 0,01277917 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 7,627E-03 0,01277041 ! glial cell development GO:0021782 28 17 0,000 7,627E-03 0,01276167 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 7,627E-03 0,01275293 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 7,627E-03 0,01274421 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 7,627E-03 0,0127355 ! myoblast differentiation GO:0045445 50 17 0,000 7,627E-03 0,0127268 ! activation of MAPKK activity GO:0000186 43 17 0,000 7,627E-03 0,01271811 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 7,627E-03 0,01270944 ! regulation of survival gene product expression GO:0045884 38 17 0,000 7,627E-03 0,01270077 ! cardiac muscle tissue development GO:0048738 34 17 0,000 7,627E-03 0,01269212 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 7,627E-03 0,01268348 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 7,627E-03 0,01267485 ! complement activation, alternative pathway GO:0006957 19 17 0,000 7,627E-03 0,01266624 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 7,627E-03 0,01265763 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 7,627E-03 0,01264904 ! membrane budding GO:0006900 42 17 0,000 7,627E-03 0,01264046 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 7,627E-03 0,01263189 ! regulation of protein binding GO:0043393 33 17 0,000 7,627E-03 0,01262333 ! nucleobase metabolic process GO:0009112 43 17 0,000 7,627E-03 0,01261478 ! DNA unwinding during replication GO:0006268 26 17 0,000 7,627E-03 0,01260625 ! genitalia development GO:0048806 32 17 0,000 7,627E-03 0,01259772 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 7,627E-03 0,01258921 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 7,627E-03 0,01258071 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 7,627E-03 0,01257222 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 7,627E-03 0,01256374 ! neutrophil chemotaxis GO:0030593 29 17 0,000 7,627E-03 0,01255528 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 7,627E-03 0,01254682 ! steroid catabolic process GO:0006706 34 17 0,000 7,627E-03 0,01253838 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 7,627E-03 0,01252995 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 7,627E-03 0,01252153 ! gas transport GO:0015669 26 17 0,000 7,627E-03 0,01251312 ! organic cation transport GO:0015695 32 17 0,000 7,627E-03 0,01250472 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 7,627E-03 0,01249633 ! RNA 3'-end processing GO:0031123 37 17 0,000 7,627E-03 0,01248796 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 7,627E-03 0,01247959 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 8,074E-03 0,01320206 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 8,074E-03 0,01319323 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 8,074E-03 0,01318441 ! limbic system development GO:0021761 40 18 0,000 8,074E-03 0,0131756 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 8,074E-03 0,01316681 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 8,074E-03 0,01315802 ! adult walking behavior GO:0007628 36 18 0,000 8,074E-03 0,01314925 ! patterning of blood vessels GO:0001569 43 18 0,000 8,074E-03 0,01314049 ! heart looping GO:0001947 34 18 0,000 8,074E-03 0,01313174 ! ciliary or flagellar motility GO:0001539 32 18 0,000 8,074E-03 0,013123 ! regulation of viral genome replication GO:0045069 30 18 0,000 8,074E-03 0,01311428 ! centrosome cycle GO:0007098 26 18 0,000 8,074E-03 0,01310556 ! positive regulation of proteolysis GO:0045862 36 18 0,000 8,074E-03 0,01309686 ! regulation of defense response to virus GO:0050688 35 18 0,000 8,074E-03 0,01308817 ! glycine metabolic process GO:0006544 30 18 0,000 8,074E-03 0,01307949 ! glutamine metabolic process GO:0006541 29 18 0,000 8,074E-03 0,01307082 ! response to retinoic acid GO:0032526 31 18 0,000 8,074E-03 0,01306217 ! cell-substrate junction assembly GO:0007044 56 18 0,000 8,074E-03 0,01305352 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 8,074E-03 0,01304489 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 8,074E-03 0,01303627 ! DNA integration GO:0015074 32 18 0,000 8,074E-03 0,01302766 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 8,074E-03 0,01301906 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 8,074E-03 0,01301047 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 8,074E-03 0,01300189 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 8,074E-03 0,01299333 ! neural crest cell migration GO:0001755 41 18 0,000 8,074E-03 0,01298478 ! long-chain fatty acid transport GO:0015909 32 18 0,000 8,074E-03 0,01297623 ! sphingolipid catabolic process GO:0030149 32 18 0,000 8,074E-03 0,0129677 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 8,074E-03 0,01295918 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 8,074E-03 0,01295067 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 8,074E-03 0,01294217 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 8,074E-03 0,01293369 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 8,074E-03 0,01292521 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 8,074E-03 0,01291675 ! detection of bacterium GO:0016045 22 18 0,000 8,074E-03 0,01290829 ! nerve development GO:0021675 34 18 0,000 8,074E-03 0,01289985 ! defense response to virus GO:0051607 43 18 0,000 8,074E-03 0,01289142 ! microspike assembly GO:0030035 46 18 0,000 8,074E-03 0,012883 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 8,074E-03 0,01287459 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 8,074E-03 0,01286619 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 8,52E-03 0,01356927 ! positive regulation of translation GO:0045727 31 19 0,000 8,52E-03 0,01356043 ! negative regulation of defense response GO:0031348 27 19 0,000 8,52E-03 0,0135516 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 8,52E-03 0,01354278 ! neuron maturation GO:0042551 46 19 0,000 8,52E-03 0,01353398 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 8,52E-03 0,01352518 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 8,52E-03 0,0135164 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 8,52E-03 0,01350763 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 8,52E-03 0,01349887 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 8,52E-03 0,01349012 ! inositol metabolic process GO:0006020 33 19 0,000 8,52E-03 0,01348138 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 8,52E-03 0,01347266 ! memory GO:0007613 34 19 0,000 8,52E-03 0,01346394 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 8,52E-03 0,01345524 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 8,52E-03 0,01344655 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 8,52E-03 0,01343787 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 8,52E-03 0,0134292 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 8,52E-03 0,01342054 ! cerebral cortex development GO:0021987 40 19 0,000 8,52E-03 0,01341189 ! pigmentation during development GO:0048066 42 19 0,000 8,52E-03 0,01340326 ! response to vitamin A GO:0033189 32 19 0,000 8,52E-03 0,01339463 ! heme metabolic process GO:0042168 40 19 0,000 8,52E-03 0,01338602 ! neuromuscular junction development GO:0007528 43 19 0,000 8,52E-03 0,01337741 ! response to lipopolysaccharide GO:0032496 34 19 0,000 8,52E-03 0,01336882 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 8,52E-03 0,01336024 ! response to fungus GO:0009620 26 19 0,000 8,52E-03 0,01335167 ! peptide cross-linking GO:0018149 39 19 0,000 8,52E-03 0,01334311 ! protein export from nucleus GO:0006611 40 19 0,000 8,52E-03 0,01333457 ! heart process GO:0003015 32 19 0,000 8,52E-03 0,01332603 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 8,52E-03 0,0133175 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 8,52E-03 0,01330899 ! visual learning GO:0008542 38 19 0,000 8,52E-03 0,01330048 ! cellular pigmentation GO:0033059 37 19 0,000 8,52E-03 0,01329199 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 8,52E-03 0,01328351 ! peptide biosynthetic process GO:0043043 26 19 0,000 8,52E-03 0,01327504 ! vitamin transport GO:0051180 31 19 0,000 8,52E-03 0,01326657 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 8,52E-03 0,01325812 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 8,52E-03 0,01324969 ! proximal/distal pattern formation GO:0009954 33 19 0,000 8,52E-03 0,01324126 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 8,52E-03 0,01323284 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 8,52E-03 0,01322443 ! cilium assembly GO:0042384 38 19 0,000 8,52E-03 0,01321604 ! peptide hormone secretion GO:0030072 32 19 0,000 8,52E-03 0,01320765 ! protein secretion GO:0009306 45 20 0,000 8,967E-03 0,01389104 ! protein import into nucleus, docking GO:0000059 42 20 0,000 8,967E-03 0,01388224 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 8,967E-03 0,01387345 ! positive regulation of ossification GO:0045778 50 20 0,000 8,967E-03 0,01386467 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 8,967E-03 0,0138559 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 8,967E-03 0,01384714 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 8,967E-03 0,01383839 ! protein amino acid deacetylation GO:0006476 34 20 0,000 8,967E-03 0,01382966 ! protein amino acid acetylation GO:0006473 41 20 0,000 8,967E-03 0,01382093 ! aminoglycan catabolic process GO:0006026 25 20 0,000 8,967E-03 0,01381222 ! response to vitamin GO:0033273 36 20 0,000 8,967E-03 0,01380351 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 8,967E-03 0,01379482 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 8,967E-03 0,01378614 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 8,967E-03 0,01377747 ! bile acid metabolic process GO:0008206 34 20 0,000 8,967E-03 0,01376881 ! response to alkaloid GO:0043279 38 20 0,000 8,967E-03 0,01376016 ! retinoid metabolic process GO:0001523 34 20 0,000 8,967E-03 0,01375152 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 8,967E-03 0,0137429 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 8,967E-03 0,01373428 ! DNA duplex unwinding GO:0032508 30 20 0,000 8,967E-03 0,01372567 GO:0032392|DNA geometric change, ! actin filament bundle formation GO:0051017 47 20 0,000 8,967E-03 0,01371708 ! body fluid secretion GO:0007589 33 20 0,000 8,967E-03 0,0137085 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 8,967E-03 0,01369992 ! peptide secretion GO:0002790 38 20 0,000 8,967E-03 0,01369136 ! behavioral interaction between organisms GO:0051705 47 20 0,000 8,967E-03 0,01368281 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 8,967E-03 0,01367427 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 8,967E-03 0,01366574 ! protein localization in mitochondrion GO:0070585 39 20 0,000 8,967E-03 0,01365722 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 8,967E-03 0,01364871 ! cell-cell junction organization GO:0045216 43 20 0,000 8,967E-03 0,01364021 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 8,967E-03 0,01363172 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 8,967E-03 0,01362324 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 8,967E-03 0,01361478 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 8,967E-03 0,01360632 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 8,967E-03 0,01359787 ! regulation of glucose import GO:0046324 30 20 0,000 8,967E-03 0,01358944 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 8,967E-03 0,01358101 ! negative regulation of T cell activation GO:0050868 41 20 0,000 8,967E-03 0,0135726 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 8,967E-03 0,0135642 ! negative regulation of coagulation GO:0050819 30 20 0,000 8,967E-03 0,0135558 ! regulation of cell killing GO:0031341 46 21 0,000 9,413E-03 0,01422179 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 9,413E-03 0,014213 ! hormone secretion GO:0046879 39 21 0,000 9,413E-03 0,01420422 ! lipid phosphorylation GO:0046834 43 21 0,000 9,413E-03 0,01419545 ! cAMP metabolic process GO:0046058 41 21 0,000 9,413E-03 0,0141867 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 9,413E-03 0,01417795 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 9,413E-03 0,01416922 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 9,413E-03 0,01416049 ! ovarian follicle development GO:0001541 39 21 0,000 9,413E-03 0,01415178 ! smooth muscle contraction GO:0006939 48 21 0,000 9,413E-03 0,01414307 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 9,413E-03 0,01413438 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 9,413E-03 0,0141257 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 9,413E-03 0,01411703 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 9,413E-03 0,01410837 ! plasma membrane fusion GO:0045026 33 21 0,000 9,413E-03 0,01409972 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 9,413E-03 0,01409108 ! prostaglandin metabolic process GO:0006693 43 21 0,000 9,413E-03 0,01408245 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 9,413E-03 0,01407383 ! sensory perception of pain GO:0019233 33 21 0,000 9,413E-03 0,01406522 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 9,413E-03 0,01405662 ! diencephalon development GO:0021536 36 21 0,000 9,413E-03 0,01404804 ! collagen fibril organization GO:0030199 62 21 0,000 9,413E-03 0,01403946 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 9,413E-03 0,01403089 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 9,413E-03 0,01402234 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 9,413E-03 0,01401379 ! vitamin A metabolic process GO:0006776 35 21 0,000 9,413E-03 0,01400526 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 9,413E-03 0,01399674 ! collagen catabolic process GO:0030574 29 21 0,000 9,413E-03 0,01398822 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 9,413E-03 0,01397972 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 9,413E-03 0,01397123 ! sperm-egg recognition GO:0035036 23 21 0,000 9,413E-03 0,01396274 ! actin filament-based movement GO:0030048 47 21 0,000 9,413E-03 0,01395427 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 9,413E-03 0,01394581 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 9,859E-03 0,01459796 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 9,859E-03 0,01458912 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 9,859E-03 0,01458029 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 9,859E-03 0,01457147 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 9,859E-03 0,01456266 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 9,859E-03 0,01455386 ! microtubule-based transport GO:0010970 59 22 0,000 9,859E-03 0,01454507 ! glutamate signaling pathway GO:0007215 48 22 0,000 9,859E-03 0,01453629 ! inactivation of MAPK activity GO:0000188 45 22 0,000 9,859E-03 0,01452752 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 9,859E-03 0,01451877 ! cellular response to starvation GO:0009267 37 22 0,000 9,859E-03 0,01451002 ! vacuolar transport GO:0007034 41 22 0,000 9,859E-03 0,01450129 ! central nervous system neuron development GO:0021954 47 22 0,000 9,859E-03 0,01449256 ! fucose metabolic process GO:0006004 44 22 0,000 9,859E-03 0,01448385 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 9,859E-03 0,01447514 ! D-ribose metabolic process GO:0006014 36 22 0,000 9,859E-03 0,01446645 ! apoptotic nuclear changes GO:0030262 34 22 0,000 9,859E-03 0,01445776 ! ureteric bud development GO:0001657 50 22 0,000 9,859E-03 0,01444909 ! cell aging GO:0007569 48 22 0,000 9,859E-03 0,01444043 ! stem cell differentiation GO:0048863 57 22 0,000 9,859E-03 0,01443178 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 9,859E-03 0,01442314 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 9,859E-03 0,0144145 ! cytolysis GO:0019835 27 22 0,000 9,859E-03 0,01440588 ! renal system process GO:0003014 42 22 0,000 9,859E-03 0,01439727 ! vasodilation GO:0042311 40 22 0,000 9,859E-03 0,01438867 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 9,859E-03 0,01438008 ! positive regulation of locomotion GO:0040017 44 22 0,000 9,859E-03 0,0143715 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 9,859E-03 0,01436293 ! detection of chemical stimulus GO:0009593 42 22 0,000 9,859E-03 0,01435437 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 9,859E-03 0,01434582 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 9,859E-03 0,01433728 ! regulation of cytokine secretion GO:0050707 41 22 0,000 9,859E-03 0,01432875 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 9,859E-03 0,01432024 ! sarcomere organization GO:0045214 32 22 0,000 9,859E-03 0,01431173 ! positive regulation of B cell activation GO:0050871 42 22 0,000 9,859E-03 0,01430323 ! response to cytokine stimulus GO:0034097 69 22 0,000 9,859E-03 0,01429474 ! activation of JUN kinase activity GO:0007257 47 22 0,000 9,859E-03 0,01428626 ! terpenoid metabolic process GO:0006721 40 22 0,000 9,859E-03 0,01427779 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 9,859E-03 0,01426933 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 9,859E-03 0,01426089 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 9,859E-03 0,01425245 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 9,859E-03 0,01424402 ! protein stabilization GO:0050821 41 22 0,000 9,859E-03 0,0142356 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,01030543 0,01487075 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,01030543 0,01486197 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,01030543 0,0148532 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,01030543 0,01484444 ! gluconeogenesis GO:0006094 38 23 0,000 0,01030543 0,0148357 ! glycerol metabolic process GO:0006071 40 23 0,000 0,01030543 0,01482696 ! viral genome replication GO:0019079 44 23 0,000 0,01030543 0,01481823 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,01030543 0,01480951 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,01030543 0,01480081 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,01030543 0,01479211 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,01030543 0,01478343 ! regeneration GO:0031099 42 23 0,000 0,01030543 0,01477475 ! axis specification GO:0009798 43 23 0,000 0,01030543 0,01476609 ! visual behavior GO:0007632 46 23 0,000 0,01030543 0,01475743 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,01030543 0,01474878 ! response to ethanol GO:0045471 47 23 0,000 0,01030543 0,01474015 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,01030543 0,01473152 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,01030543 0,01472291 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,01030543 0,0147143 ! peroxisome organization GO:0007031 43 23 0,000 0,01030543 0,01470571 ! lysosome organization GO:0007040 47 23 0,000 0,01030543 0,01469713 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,01030543 0,01468855 ! vesicle targeting GO:0006903 49 23 0,000 0,01030543 0,01467999 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,01030543 0,01467143 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,01030543 0,01466289 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,01030543 0,01465435 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,01030543 0,01464583 ! DNA modification GO:0006304 36 23 0,000 0,01030543 0,01463731 ! fatty acid transport GO:0015908 47 23 0,000 0,01030543 0,01462881 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,01030543 0,01462031 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,01030543 0,01461183 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,01030543 0,01460335 ! hormone transport GO:0009914 41 23 0,000 0,01030543 0,01459488 ! cell-cell recognition GO:0009988 28 23 0,000 0,01030543 0,01458643 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,01030543 0,01457798 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,01030543 0,01456955 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,01030543 0,01456112 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,01075123 0,01518223 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,01075123 0,01517346 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,01075123 0,0151647 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,01075123 0,01515595 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,01075123 0,01514721 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,01075123 0,01513848 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,01075123 0,01512975 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,01075123 0,01512104 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,01075123 0,01511234 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,01075123 0,01510365 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,01075123 0,01509497 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,01075123 0,0150863 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,01075123 0,01507764 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,01075123 0,01506899 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,01075123 0,01506035 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,01075123 0,01505172 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,01075123 0,0150431 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,01075123 0,01503449 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,01075123 0,01502589 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,01075123 0,0150173 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,01075123 0,01500872 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,01075123 0,01500015 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,01075123 0,01499158 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,01075123 0,01498303 ! membrane depolarization GO:0051899 45 24 0,000 0,01075123 0,01497449 ! pallium development GO:0021543 56 24 0,000 0,01075123 0,01496596 ! oogenesis GO:0048477 44 24 0,000 0,01075123 0,01495743 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,01075123 0,01494892 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,01075123 0,01494042 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,01075123 0,01493192 ! platelet activation GO:0030168 41 24 0,000 0,01075123 0,01492344 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,01075123 0,01491497 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,01075123 0,0149065 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,01075123 0,01489805 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,01075123 0,0148896 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,01075123 0,01488116 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,01075123 0,01487274 ! regulation of amine transport GO:0051952 41 24 0,000 0,01075123 0,01486432 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,01075123 0,01485591 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,01119684 0,0154629 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,01119684 0,01545417 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,01119684 0,01544544 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,01119684 0,01543672 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,01119684 0,01542802 ! leukocyte adhesion GO:0007159 55 25 0,000 0,01119684 0,01541932 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,01119684 0,01541063 ! phototransduction GO:0007602 37 25 0,000 0,01119684 0,01540196 ! keratinization GO:0031424 37 25 0,000 0,01119684 0,01539329 ! vasculogenesis GO:0001570 49 25 0,000 0,01119684 0,01538463 ! vacuole organization GO:0007033 49 25 0,000 0,01119684 0,01537598 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,01119684 0,01536734 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,01119684 0,01535872 ! receptor metabolic process GO:0043112 53 25 0,000 0,01119684 0,0153501 ! chromosome condensation GO:0030261 48 25 0,000 0,01119684 0,01534149 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,01119684 0,01533289 ! regulation of behavior GO:0050795 48 25 0,000 0,01119684 0,0153243 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,01119684 0,01531572 ! interaction with host GO:0051701 66 25 0,000 0,01119684 0,01530715 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,01119684 0,01529859 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,01119684 0,01529004 ! immunoglobulin production GO:0002377 62 25 0,000 0,01119684 0,01528149 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,01119684 0,01527296 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,01119684 0,01526444 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,01119684 0,01525593 ! liver development GO:0001889 55 25 0,000 0,01119684 0,01524742 ! protein tetramerization GO:0051262 57 25 0,000 0,01119684 0,01523893 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,01164226 0,01583632 ! myelination GO:0042552 50 26 0,000 0,01164226 0,01582751 ! initiation of viral infection GO:0019059 60 26 0,000 0,01164226 0,01581871 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,01164226 0,01580991 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,01164226 0,01580113 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,01164226 0,01579236 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,01164226 0,01578359 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,01164226 0,01577484 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,01164226 0,01576609 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,01164226 0,01575736 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,01164226 0,01574863 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,01164226 0,01573992 ! digestive system process GO:0022600 49 26 0,000 0,01164226 0,01573121 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,01164226 0,01572252 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,01164226 0,01571383 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,01164226 0,01570515 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,01164226 0,01569649 ! osteoblast differentiation GO:0001649 63 26 0,000 0,01164226 0,01568783 ! neural crest cell development GO:0014032 59 26 0,000 0,01164226 0,01567918 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,01164226 0,01567054 ! negative regulation of cell development GO:0010721 83 26 0,000 0,01164226 0,01566191 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,01164226 0,01565329 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,01164226 0,01564468 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,01164226 0,01563608 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,01164226 0,01562749 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,01164226 0,01561891 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,01164226 0,01561034 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,01164226 0,01560177 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,01164226 0,01559322 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,01164226 0,01558468 ! blastocyst development GO:0001824 50 26 0,000 0,01164226 0,01557614 ! telomere organization GO:0032200 46 26 0,000 0,01164226 0,01556762 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,01164226 0,0155591 ! neural tube closure GO:0001843 58 26 0,000 0,01164226 0,01555059 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,01164226 0,01554209 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,01164226 0,01553361 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,01164226 0,01552513 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,01208749 0,01611006 ! embryonic pattern specification GO:0009880 49 27 0,000 0,01208749 0,01610127 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,01208749 0,0160925 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,01208749 0,01608373 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,01208749 0,01607498 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,01208749 0,01606623 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,01208749 0,0160575 ! iron ion transport GO:0006826 65 27 0,000 0,01208749 0,01604877 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,01208749 0,01604005 ! superoxide metabolic process GO:0006801 41 27 0,000 0,01208749 0,01603134 ! tube lumen formation GO:0035148 59 27 0,000 0,01208749 0,01602264 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,01208749 0,01601396 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,01208749 0,01600528 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,01208749 0,01599661 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,01208749 0,01598794 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,01208749 0,01597929 ! response to starvation GO:0042594 47 27 0,000 0,01208749 0,01597065 ! response to toxin GO:0009636 49 27 0,000 0,01208749 0,01596202 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,01208749 0,01595339 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,01208749 0,01594478 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,01208749 0,01593618 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,01208749 0,01592758 ! leukocyte proliferation GO:0070661 59 27 0,000 0,01208749 0,01591899 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,01208749 0,01591042 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,01253253 0,01648733 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,01253253 0,01647846 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,01253253 0,01646959 ! protein amino acid acylation GO:0043543 59 28 0,000 0,01253253 0,01646074 ! vesicle docking GO:0048278 55 28 0,000 0,01253253 0,01645189 ! circadian rhythm GO:0007623 56 28 0,000 0,01253253 0,01644306 ! dendrite development GO:0016358 67 28 0,000 0,01253253 0,01643423 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,01253253 0,01642542 ! sperm motility GO:0030317 37 28 0,000 0,01253253 0,01641661 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,01253253 0,01640781 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,01253253 0,01639902 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,01253253 0,01639024 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,01253253 0,01638147 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,01253253 0,01637271 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,01253253 0,01636396 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,01253253 0,01635522 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,01253253 0,01634649 ! glutathione metabolic process GO:0006749 42 28 0,000 0,01253253 0,01633777 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,01253253 0,01632905 ! lipid oxidation GO:0034440 48 28 0,000 0,01253253 0,01632035 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,01253253 0,01631165 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,01253253 0,01630297 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,01297739 0,01687267 ! translational initiation GO:0006413 66 29 0,000 0,01297739 0,0168637 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,01297739 0,01685473 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,01297739 0,01684578 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,01297739 0,01683683 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,01297739 0,0168279 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,01297739 0,01681897 ! primary neural tube formation GO:0014020 61 29 0,000 0,01297739 0,01681005 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,01297739 0,01680114 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,01297739 0,01679224 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,01297739 0,01678335 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,01297739 0,01677447 ! somitogenesis GO:0001756 52 29 0,000 0,01297739 0,0167656 ! synaptogenesis GO:0007416 46 29 0,000 0,01297739 0,01675674 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,01297739 0,01674789 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,01297739 0,01673905 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,01297739 0,01673021 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,01342205 0,01729434 ! phenol metabolic process GO:0018958 56 30 0,000 0,01342205 0,01728523 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,01342205 0,01727612 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,01342205 0,01726702 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,01342205 0,01725794 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,01342205 0,01724886 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,01342205 0,01723979 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,01342205 0,01723073 ! acute-phase response GO:0006953 50 30 0,000 0,01342205 0,01722168 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,01342205 0,01721264 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,01342205 0,01720361 ! myofibril assembly GO:0030239 50 30 0,000 0,01342205 0,01719459 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,01342205 0,01718558 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,01342205 0,01717657 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 64 30 0,000 0,01342205 0,01716758 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,01342205 0,0171586 ! phospholipid transport GO:0015914 65 30 0,000 0,01342205 0,01714962 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,01342205 0,01714066 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,01342205 0,0171317 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,01342205 0,01712276 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,01342205 0,01711382 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,01342205 0,01710489 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,01342205 0,01709597 ! regulation of coagulation GO:0050818 52 30 0,000 0,01342205 0,01708707 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,01386653 0,01764372 ! zinc ion transport GO:0006829 54 31 0,000 0,01386653 0,01763453 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,01386653 0,01762536 ! cell junction assembly GO:0034329 85 31 0,000 0,01386653 0,01761619 ! regulation of innate immune response GO:0045088 57 31 0,000 0,01386653 0,01760704 ! ovulation cycle process GO:0022602 55 31 0,000 0,01386653 0,01759789 ! peptide transport GO:0015833 60 31 0,000 0,01386653 0,01758875 ! male gonad development GO:0008584 56 31 0,000 0,01386653 0,01757963 ! iron ion homeostasis GO:0055072 60 31 0,000 0,01386653 0,01757051 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,01386653 0,0175614 ! detection of light stimulus GO:0009583 44 31 0,000 0,01386653 0,0175523 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,01386653 0,01754321 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,01386653 0,01753413 ! natural killer cell activation GO:0030101 50 31 0,000 0,01386653 0,01752506 ! ensheathment of neurons GO:0007272 64 31 0,000 0,01386653 0,017516 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,01386653 0,01750695 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,01386653 0,0174979 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,01386653 0,01748887 ! eye morphogenesis GO:0048592 65 31 0,000 0,01386653 0,01747985 ! response to heat GO:0009408 54 31 0,000 0,01386653 0,01747083 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,01386653 0,01746183 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,01431083 0,01801203 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,01431083 0,01800275 ! collagen metabolic process GO:0032963 49 32 0,000 0,01431083 0,01799349 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,01431083 0,01798423 ! spindle organization GO:0007051 50 32 0,000 0,01431083 0,01797499 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,01431083 0,01796575 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,01431083 0,01795652 ! metanephros development GO:0001656 81 32 0,000 0,01431083 0,0179473 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,01431083 0,01793809 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,01431083 0,0179289 ! muscle cell development GO:0055001 52 32 0,000 0,01431083 0,01791971 ! mesoderm formation GO:0001707 73 32 0,000 0,01431083 0,01791053 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,01431083 0,01790135 ! ovulation cycle GO:0042698 57 32 0,000 0,01431083 0,01789219 ! peripheral nervous system development GO:0007422 68 32 0,000 0,01431083 0,01788304 ! BMP signaling pathway GO:0030509 71 32 0,000 0,01431083 0,0178739 ! hindbrain development GO:0030902 65 32 0,000 0,01431083 0,01786477 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,01431083 0,01785564 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,01431083 0,01784653 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,01431083 0,01783742 ! gene silencing GO:0016458 71 32 0,000 0,01431083 0,01782833 ! regulation of pH GO:0006885 56 33 0,000 0,01475493 0,01837222 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,01475493 0,01836286 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,01475493 0,01835351 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,01475493 0,01834417 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,01475493 0,01833484 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,01475493 0,01832552 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,01475493 0,01831621 ! response to ionizing radiation GO:0010212 74 33 0,000 0,01475493 0,0183069 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,01475493 0,01829761 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,01475493 0,01828833 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,01475493 0,01827905 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,01475493 0,01826979 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,01475493 0,01826053 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,01475493 0,01825129 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,01475493 0,01824205 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,01519885 0,01878138 ! post-embryonic development GO:0009791 76 34 0,000 0,01519885 0,01877188 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,01519885 0,0187624 ! cholesterol transport GO:0030301 62 34 0,000 0,01519885 0,01875292 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,01519885 0,01874345 ! spliceosome assembly GO:0000245 75 34 0,000 0,01519885 0,018734 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,01519885 0,01872455 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,01519885 0,01871511 ! formation of primary germ layer GO:0001704 76 34 0,000 0,01519885 0,01870568 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,01519885 0,01869626 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,01519885 0,01868685 ! adult locomotory behavior GO:0008344 62 34 0,000 0,01519885 0,01867746 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,01519885 0,01866806 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,01564258 0,01920342 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,01564258 0,01919378 ! negative regulation of secretion GO:0051048 68 35 0,000 0,01564258 0,01918414 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,01564258 0,01917452 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,01564258 0,0191649 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,01564258 0,01915529 ! membrane docking GO:0022406 69 35 0,000 0,01564258 0,0191457 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,01564258 0,01913611 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,01564258 0,01912653 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,01564258 0,01911696 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,01564258 0,01910741 ! ceramide metabolic process GO:0006672 72 35 0,000 0,01564258 0,01909786 ! telencephalon development GO:0021537 81 35 0,000 0,01564258 0,01908832 ! sterol transport GO:0015918 63 35 0,000 0,01564258 0,01907879 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,01564258 0,01906927 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,01564258 0,01905976 ! placenta development GO:0001890 53 35 0,000 0,01564258 0,01905025 ! vesicle localization GO:0051648 70 35 0,000 0,01564258 0,01904076 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,01608612 0,01957091 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,01608612 0,01956117 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,01608612 0,01955143 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,01608612 0,01954171 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,01608612 0,019532 ! positive regulation of cell development GO:0010720 85 36 0,000 0,01608612 0,0195223 ! protein targeting to membrane GO:0006612 75 36 0,000 0,01608612 0,0195126 ! regulation of proteolysis GO:0030162 77 36 0,000 0,01608612 0,01950292 ! aerobic respiration GO:0009060 56 36 0,000 0,01608612 0,01949325 ! cytokine production GO:0001816 68 36 0,000 0,01608612 0,01948358 ! embryonic organ development GO:0048568 67 36 0,000 0,01608612 0,01947393 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,01608612 0,01946428 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,01608612 0,01945465 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,01652947 0,01998095 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,01652947 0,01997107 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,01652947 0,01996119 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,01652947 0,01995133 ! sister chromatid segregation GO:0000819 65 37 0,000 0,01652947 0,01994148 ! odontogenesis GO:0042476 74 37 0,000 0,01652947 0,01993164 ! actomyosin structure organization GO:0031032 68 37 0,000 0,01652947 0,0199218 ! cell junction organization GO:0034330 96 37 0,000 0,01652947 0,01991198 ! tissue remodeling GO:0048771 78 37 0,000 0,01652947 0,01990217 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,01652947 0,01989236 ! female gonad development GO:0008585 71 37 0,000 0,01652947 0,01988257 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,01652947 0,01987278 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,01652947 0,01986301 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,01652947 0,01985324 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,01652947 0,01984349 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,01697264 0,0203655 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,01697264 0,0203555 ! meiosis I GO:0007127 74 38 0,000 0,01697264 0,02034551 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,01697264 0,02033553 ! organic anion transport GO:0015711 82 38 0,000 0,01697264 0,02032557 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,01697264 0,02031561 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,01697264 0,02030566 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,01697264 0,02029572 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,01697264 0,02028579 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,01697264 0,02027587 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,01697264 0,02026596 ! regulation of protein stability GO:0031647 77 38 0,000 0,01697264 0,02025606 ! spermatid development GO:0007286 69 38 0,000 0,01697264 0,02024617 ! pigment metabolic process GO:0042440 87 38 0,000 0,01697264 0,02023629 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,01697264 0,02022642 ! neural tube formation GO:0001841 79 38 0,000 0,01697264 0,02021655 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,01741562 0,02073409 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,01741562 0,02072399 ! negative regulation of binding GO:0051100 71 39 0,000 0,01741562 0,0207139 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,01741562 0,02070382 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,01741562 0,02069375 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,01741562 0,02068369 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,01741562 0,02067364 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,01741562 0,0206636 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,01741562 0,02065357 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,01741562 0,02064355 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,01741562 0,02063354 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,01785841 0,02114789 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,01785841 0,02113764 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,01785841 0,02112741 ! learning GO:0007612 82 40 0,000 0,01785841 0,02111718 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,01785841 0,02110696 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,01785841 0,02109676 ! lipid homeostasis GO:0055088 75 40 0,000 0,01785841 0,02108656 ! mismatch repair GO:0006298 58 40 0,000 0,01785841 0,02107637 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,01785841 0,0210662 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,01785841 0,02105603 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,01785841 0,02104587 ! mRNA catabolic process GO:0006402 79 41 0,000 0,01830102 0,02155708 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,01830102 0,02154669 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,01830102 0,02153631 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,01830102 0,02152594 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,01830102 0,02151558 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,01830102 0,02150523 ! feeding behavior GO:0007631 69 41 0,000 0,01830102 0,02149489 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,01830102 0,02148457 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,01830102 0,02147425 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,01830102 0,02146394 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,01830102 0,02145364 ! spermatid differentiation GO:0048515 73 41 0,000 0,01830102 0,02144335 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,01830102 0,02143307 ! RNA modification GO:0009451 64 41 0,000 0,01830102 0,0214228 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,01874343 0,02193018 ! ear morphogenesis GO:0042471 64 42 0,000 0,01874343 0,02191968 ! organic ether metabolic process GO:0018904 59 42 0,000 0,01874343 0,02190919 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,01874343 0,02189871 ! T cell differentiation GO:0030217 93 42 0,000 0,01874343 0,02188825 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,01874343 0,02187779 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,01874343 0,02186734 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,01874343 0,0218569 ! regulation of protein secretion GO:0050708 77 42 0,000 0,01874343 0,02184647 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,01874343 0,02183606 ! cytokinesis GO:0000910 84 42 0,000 0,01874343 0,02182565 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,01874343 0,02181525 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,01918567 0,02231932 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,01918567 0,0223087 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,01918567 0,02229809 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,01918567 0,02228749 ! regulation of tube size GO:0035150 76 43 0,000 0,01918567 0,02227689 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,01918567 0,02226631 ! glucose transport GO:0015758 66 43 0,000 0,01918567 0,02225574 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,01918567 0,02224517 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,01918567 0,02223462 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,01918567 0,02222408 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,01918567 0,02221355 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,01918567 0,02220302 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,01918567 0,02219251 ! segmentation GO:0035282 78 43 0,000 0,01918567 0,02218201 ! ion transmembrane transport GO:0034220 79 43 0,000 0,01918567 0,02217151 ! neuron migration GO:0001764 85 43 0,000 0,01918567 0,02216103 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,01918567 0,02215056 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,01962771 0,02265021 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,01962771 0,02263952 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,01962771 0,02262883 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,01962771 0,02261816 ! hexose transport GO:0008645 68 44 0,000 0,01962771 0,02260749 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,01962771 0,02259684 ! striated muscle contraction GO:0006941 85 44 0,000 0,01962771 0,0225862 ! phagocytosis GO:0006909 105 44 0,000 0,01962771 0,02257556 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,01962771 0,02256494 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,02006957 0,02306207 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,02006957 0,02305122 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,02006957 0,02304039 ! B cell differentiation GO:0030183 124 45 0,000 0,02006957 0,02302957 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,02006957 0,02301876 ! female gamete generation GO:0007292 71 45 0,000 0,02006957 0,02300796 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,02006957 0,02299716 ! polyol metabolic process GO:0019751 77 45 0,000 0,02006957 0,02298638 ! maintenance of location in cell GO:0051651 101 45 0,000 0,02006957 0,02297561 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,02051124 0,02347024 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,02051124 0,02345925 ! glycolysis GO:0006096 71 46 0,000 0,02051124 0,02344827 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,02051124 0,02343731 ! leukocyte migration GO:0050900 75 46 0,000 0,02051124 0,02342635 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,02051124 0,0234154 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,02051124 0,02340446 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,02051124 0,02339354 ! pigmentation GO:0043473 103 46 0,000 0,02051124 0,02338262 ! cell growth GO:0016049 90 46 0,000 0,02051124 0,02337172 ! neural tube development GO:0021915 91 47 0,000 0,02095272 0,02386364 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,02095272 0,02385252 ! positive regulation of defense response GO:0031349 88 48 0,000 0,02139402 0,02434355 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,02139402 0,02433221 ! mitochondrial transport GO:0006839 94 48 0,000 0,02139402 0,02432089 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,02139402 0,02430958 ! cellular component disassembly GO:0022411 89 48 0,000 0,02139402 0,02429828 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,02139402 0,02428699 ! endosome transport GO:0016197 127 48 0,000 0,02139402 0,02427571 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,02139402 0,02426444 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,02139402 0,02425318 ! male sex differentiation GO:0046661 93 48 0,000 0,02139402 0,02424193 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,02139402 0,02423069 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,02139402 0,02421946 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,02139402 0,02420824 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,02139402 0,02419704 ! methylation GO:0032259 97 48 0,000 0,02139402 0,02418584 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,02183513 0,0246731 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,02183513 0,02466169 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,02183513 0,02465029 ! JNK cascade GO:0007254 106 49 0,000 0,02183513 0,02463891 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,02183513 0,02462753 ! protein homooligomerization GO:0051260 84 49 0,000 0,02183513 0,02461617 ! regulation of action potential GO:0001508 102 50 0,000 0,02227606 0,02510167 ! regulation of ion transport GO:0043269 86 50 0,000 0,02227606 0,02509009 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,02227606 0,02507853 ! endocrine system development GO:0035270 109 50 0,000 0,02227606 0,02506698 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,02227606 0,02505544 ! activation of caspase activity GO:0006919 95 50 0,000 0,02227606 0,02504391 ! regulation of ossification GO:0030278 123 50 0,000 0,02227606 0,02503239 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,02227606 0,02502088 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,02227606 0,02500938 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,02227606 0,02499789 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,02227606 0,02498641 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,0227168 0,02546909 ! viral infectious cycle GO:0019058 104 51 0,000 0,0227168 0,0254574 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,0227168 0,02544573 ! peptide metabolic process GO:0006518 80 51 0,000 0,0227168 0,02543407 ! response to temperature stimulus GO:0009266 84 51 0,000 0,0227168 0,02542242 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,0227168 0,02541078 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,0227168 0,02539915 ! positive regulation of binding GO:0051099 88 52 0,000 0,02315735 0,02587987 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,02315735 0,02586804 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,02315735 0,02585622 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,02315735 0,02584441 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,02315735 0,02583261 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,02315735 0,02582082 ! excretion GO:0007588 87 52 0,000 0,02315735 0,02580904 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,02315735 0,02579727 ! histone modification GO:0016570 104 52 0,000 0,02315735 0,02578551 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,02315735 0,02577376 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,02315735 0,02576202 ! amino acid activation GO:0043038 98 52 0,000 0,02315735 0,0257503 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,02359772 0,02622804 ! inner ear development GO:0048839 89 53 0,000 0,02359772 0,02621611 ! chromatin remodeling GO:0006338 122 53 0,000 0,02359772 0,02620419 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,02359772 0,02619229 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,02359772 0,02618039 ! vesicle organization GO:0016050 127 53 0,000 0,02359772 0,02616851 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,02359772 0,02615663 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,02359772 0,02614477 ! cartilage development GO:0051216 99 53 0,000 0,02359772 0,02613292 ! synapse organization GO:0050808 102 53 0,000 0,02359772 0,02612108 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,0240379 0,02659628 ! regulation of translational initiation GO:0006446 87 54 0,000 0,0240379 0,02658424 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,0240379 0,02657221 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,0240379 0,02656019 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,0240379 0,02654818 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,0240379 0,02653619 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,0240379 0,0265242 ! membrane fusion GO:0006944 122 54 0,000 0,0240379 0,02651223 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,0240379 0,02650026 ! covalent chromatin modification GO:0016569 115 54 0,000 0,0240379 0,02648831 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,0240379 0,02647637 ! regulation of cell shape GO:0008360 142 54 0,000 0,0240379 0,02646444 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,0240379 0,02645251 ! RNA catabolic process GO:0006401 103 55 0,000 0,02447789 0,02692458 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,02447789 0,02691246 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,02447789 0,02690035 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,02447789 0,02688826 ! cell recognition GO:0008037 98 55 0,000 0,02447789 0,02687617 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,02447789 0,0268641 ! cell maturation GO:0048469 107 55 0,000 0,02447789 0,02685204 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,02447789 0,02683999 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,02447789 0,02682794 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,0249177 0,02729773 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,0249177 0,02728549 ! glucose catabolic process GO:0006007 88 56 0,000 0,0249177 0,02727327 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,0249177 0,02726106 ! RNA elongation GO:0006354 90 56 0,000 0,0249177 0,02724885 ! chloride transport GO:0006821 102 57 0,000 0,02535732 0,0277172 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,02535732 0,0277048 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,02535732 0,02769242 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,02535732 0,02768004 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,02535732 0,02766768 ! heart morphogenesis GO:0003007 105 57 0,000 0,02535732 0,02765533 ! regulation of actin filament length GO:0030832 118 58 0,000 0,02579676 0,02812203 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,02579676 0,02810949 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,02579676 0,02809696 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,02579676 0,02808444 ! aging GO:0007568 112 58 0,000 0,02579676 0,02807193 ! gastrulation GO:0007369 122 58 0,000 0,02579676 0,02805943 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,02579676 0,02804694 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,02579676 0,02803447 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,02579676 0,028022 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,02579676 0,02800955 ! maintenance of location GO:0051235 124 58 0,000 0,02579676 0,0279971 ! establishment of organelle localization GO:0051656 122 59 0,000 0,02623601 0,02846118 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,02667507 0,02892464 ! lipid modification GO:0030258 112 60 0,000 0,02667507 0,0289118 ! DNA catabolic process GO:0006308 94 60 0,000 0,02667507 0,02889898 ! regulation of endocytosis GO:0030100 104 60 0,000 0,02667507 0,02888617 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,02667507 0,02887337 ! adult behavior GO:0030534 104 60 0,000 0,02667507 0,02886059 ! kidney development GO:0001822 133 60 0,000 0,02667507 0,02884781 ! positive regulation of secretion GO:0051047 110 61 0,000 0,02711395 0,02930946 ! regulation of cellular component size GO:0032535 125 61 0,000 0,02711395 0,0292965 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,02711395 0,02928355 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,02711395 0,02927061 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,02711395 0,02925768 ! regulation of heart contraction GO:0008016 123 61 0,000 0,02711395 0,02924476 ! camera-type eye development GO:0043010 126 61 0,000 0,02711395 0,02923186 ! proton transport GO:0015992 117 61 0,000 0,02711395 0,02921896 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,02711395 0,02920608 ! viral reproductive process GO:0022415 132 62 0,000 0,02755265 0,02966554 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,02755265 0,02965247 ! tRNA processing GO:0008033 102 62 0,000 0,02755265 0,02963942 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,02755265 0,02962637 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,02799116 0,03008464 ! regulation of mitosis GO:0007088 112 63 0,000 0,02799116 0,03007141 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,02799116 0,03005819 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,02799116 0,03004499 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,02799116 0,03003179 ! hydrogen transport GO:0006818 121 64 0,000 0,02842948 0,03048868 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,02842948 0,0304753 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,02842948 0,03046194 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,02842948 0,03044858 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,02886762 0,03090429 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,02886762 0,03089075 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,02886762 0,03087723 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,02886762 0,03086371 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,02886762 0,03085021 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,02886762 0,03083672 ! ear development GO:0043583 114 66 0,000 0,02930557 0,03129087 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,02930557 0,0312772 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,02930557 0,03126354 ! gonad development GO:0008406 115 66 0,000 0,02930557 0,03124989 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,02930557 0,03123626 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,02974334 0,03168904 ! activation of MAPK activity GO:0000187 124 67 0,000 0,02974334 0,03167523 ! chromosome segregation GO:0007059 127 67 0,000 0,02974334 0,03166143 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,02974334 0,03164764 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,02974334 0,03163386 ! secondary metabolic process GO:0019748 125 67 0,000 0,02974334 0,03162009 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,02974334 0,03160634 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,03018092 0,03205738 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,03018092 0,03204345 ! hexose catabolic process GO:0019320 113 68 0,000 0,03018092 0,03202953 ! extracellular matrix organization GO:0030198 146 68 0,000 0,03018092 0,03201563 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,03018092 0,03200173 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,03018092 0,03198785 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,03018092 0,03197397 ! viral reproduction GO:0016032 142 68 0,000 0,03018092 0,03196011 ! regulation of lipase activity GO:0060191 137 68 0,000 0,03018092 0,03194627 ! adaptive immune response GO:0002250 126 68 0,000 0,03018092 0,03193243 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,03018092 0,03191861 ! negative regulation of cell size GO:0045792 144 69 0,000 0,03061832 0,03236718 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,03061832 0,03235318 ! urogenital system development GO:0001655 149 69 0,000 0,03061832 0,03233919 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,03061832 0,03232521 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,03061832 0,03231125 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,03061832 0,0322973 ! single fertilization GO:0007338 83 69 0,000 0,03061832 0,03228336 ! cell redox homeostasis GO:0045454 114 70 0,000 0,03105553 0,03273022 ! germ cell development GO:0007281 133 70 0,000 0,03105553 0,03271611 ! activation of immune response GO:0002253 120 70 0,000 0,03105553 0,03270201 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,03105553 0,03268792 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,03149256 0,03313364 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,03149256 0,03311938 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,03149256 0,03310513 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,03149256 0,03309089 ! carbohydrate transport GO:0008643 114 72 0,000 0,0319294 0,03353548 ! actin filament organization GO:0007015 167 72 0,000 0,0319294 0,03352107 ! B cell activation GO:0042113 179 72 0,000 0,0319294 0,03350667 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,0319294 0,03349228 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,0319294 0,03347791 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,0319294 0,03346354 ! humoral immune response GO:0006959 115 73 0,000 0,03236606 0,03390664 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,03236606 0,0338921 ! regulation of immune effector process GO:0002697 156 73 0,000 0,03236606 0,03387758 ! acute inflammatory response GO:0002526 118 74 0,000 0,03280253 0,03431973 ! amino acid transport GO:0006865 148 74 0,000 0,03280253 0,03430504 ! organelle localization GO:0051640 155 74 0,000 0,03280253 0,03429036 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,03323882 0,03473158 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,03323882 0,03471673 ! reproductive structure development GO:0048608 131 75 0,000 0,03323882 0,03470189 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,03323882 0,03468707 ! eye development GO:0001654 155 75 0,000 0,03323882 0,03467226 ! axon guidance GO:0007411 162 75 0,000 0,03323882 0,03465746 ! rhythmic process GO:0048511 142 75 0,000 0,03323882 0,03464268 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,03367492 0,03508223 ! learning or memory GO:0007611 161 76 0,000 0,03367492 0,03506728 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,03367492 0,03505234 ! regulation of blood pressure GO:0008217 134 76 0,000 0,03367492 0,03503741 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,03367492 0,03502249 ! amine catabolic process GO:0009310 136 77 0,000 0,03411084 0,03546076 ! neurotransmitter transport GO:0006836 142 77 0,000 0,03411084 0,03544568 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,03411084 0,03543061 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,03411084 0,03541555 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,03411084 0,0354005 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,03411084 0,03538547 ! regulation of catabolic process GO:0009894 173 77 0,000 0,03411084 0,03537045 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,03454658 0,03580708 ! antigen processing and presentation GO:0019882 117 78 0,000 0,03454658 0,0357919 ! fertilization GO:0009566 99 78 0,000 0,03454658 0,03577672 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,03454658 0,03576156 ! blood coagulation GO:0007596 151 79 0,000 0,03498213 0,03619709 GO:0050817|coagulation, ! steroid biosynthetic process GO:0006694 146 79 0,000 0,03498213 0,03618177 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,03498213 0,03616646 ! protein oligomerization GO:0051259 149 79 0,000 0,03498213 0,03615116 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,03498213 0,03613587 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,0354175 0,03657014 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,0354175 0,03655469 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,0354175 0,03653925 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,0354175 0,03652383 ! meiosis GO:0007126 143 81 0,000 0,03585268 0,036957 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,03585268 0,03694141 ! response to hypoxia GO:0001666 178 81 0,000 0,03585268 0,03692584 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,03585268 0,03691028 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,03628768 0,03734237 ! protein import into nucleus GO:0006606 174 82 0,000 0,03628768 0,03732665 ! meiotic cell cycle GO:0051321 144 82 0,000 0,03628768 0,03731094 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,03672249 0,03774213 ! exocytosis GO:0006887 153 83 0,000 0,03672249 0,03772626 ! response to drug GO:0042493 149 83 0,000 0,03672249 0,0377104 ! response to oxygen levels GO:0070482 183 83 0,000 0,03672249 0,03769456 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,03672249 0,03767873 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,03672249 0,03766291 ! nuclear import GO:0051170 177 83 0,000 0,03672249 0,0376471 ! inorganic anion transport GO:0015698 156 83 0,000 0,03672249 0,03763131 ! T cell activation GO:0042110 189 84 0,000 0,03715712 0,03806073 ! response to nutrient GO:0007584 135 84 0,000 0,03715712 0,03804478 ! digestion GO:0007586 130 84 0,000 0,03715712 0,03802884 ! hemostasis GO:0007599 165 85 0,000 0,03759157 0,03845737 ! negative regulation of transport GO:0051051 164 85 0,000 0,03759157 0,03844127 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,03759157 0,03842519 ! negative regulation of growth GO:0045926 168 85 0,000 0,03759157 0,03840912 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,03759157 0,03839306 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,03759157 0,03837702 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,03759157 0,03836099 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,03802583 0,03878794 ! regulation of lyase activity GO:0051339 169 86 0,000 0,03802583 0,03877175 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,03802583 0,03875557 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,03845991 0,03918164 ! alcohol catabolic process GO:0046164 142 87 0,000 0,03845991 0,0391653 ! nucleosome assembly GO:0006334 126 87 0,000 0,03845991 0,03914899 ! cellular respiration GO:0045333 143 88 0,000 0,03889381 0,03957417 ! amine biosynthetic process GO:0009309 146 88 0,000 0,03889381 0,03955769 ! sensory perception of smell GO:0007608 117 88 0,000 0,03889381 0,03954123 ! chromatin assembly GO:0031497 128 88 0,000 0,03889381 0,03952478 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,03889381 0,03950835 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,03932752 0,03993231 ! regulation of DNA binding GO:0051101 167 89 0,000 0,03932752 0,03991572 ! cellular defense response GO:0006968 123 89 0,000 0,03932752 0,03989914 ! protein localization in nucleus GO:0034504 192 89 0,000 0,03932752 0,03988258 ! regulation of neurological system process GO:0031644 175 89 0,000 0,03932752 0,03986603 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,03976105 0,04028878 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,03976105 0,04027207 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,04019439 0,04069412 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,04019439 0,04067726 ! gland development GO:0048732 220 91 0,000 0,04019439 0,04066042 ! defense response to bacterium GO:0042742 112 91 0,000 0,04019439 0,04064359 ! bone development GO:0060348 206 92 0,000 0,04062756 0,04106459 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,04062756 0,04104761 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,04106053 0,04146791 ! amine transport GO:0015837 181 93 0,000 0,04106053 0,04145078 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,04106053 0,04143366 ! vitamin metabolic process GO:0006766 153 93 0,000 0,04106053 0,04141655 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,04149333 0,04183583 ! female pregnancy GO:0007565 166 94 0,000 0,04149333 0,04181857 ! sterol metabolic process GO:0016125 166 94 0,000 0,04149333 0,04180132 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,04149333 0,04178409 ! regulation of membrane potential GO:0042391 179 94 0,000 0,04149333 0,04176687 ! regulation of defense response GO:0031347 171 95 0,000 0,04192594 0,04218496 ! nucleosome organization GO:0034728 143 95 0,000 0,04192594 0,04216759 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,04192594 0,04215024 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,04192594 0,0421329 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,04192594 0,04211557 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,04192594 0,04209826 ! sex differentiation GO:0007548 171 96 0,000 0,04235837 0,042515 ! regulation of T cell activation GO:0050863 175 96 0,000 0,04235837 0,04249754 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,04279062 0,04291358 ! transcription initiation GO:0006352 171 97 0,000 0,04279062 0,04289597 ! leukocyte differentiation GO:0002521 232 98 0,000 0,04322268 0,04331132 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,04322268 0,04329357 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,04408626 0,04414046 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,04408626 0,04412238 ! positive regulation of immune response GO:0050778 175 100 0,000 0,04408626 0,04410431 ! hormone metabolic process GO:0042445 171 100 0,000 0,04408626 0,04408626