pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/292-3-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 1,173E-07 4,279E-04 ! skin development GO:0043588 20 17 2,000 1,413E-06 2,578E-03 ! interphase of mitotic cell cycle GO:0051329 100 81 3,000 3,839E-06 4,669E-03 ! interphase GO:0051325 103 83 3,000 4,233E-06 3,861E-03 ! enucleate erythrocyte differentiation GO:0043353 7 5 1,000 1,708E-05 0,01246178 ! platelet-derived growth factor binding GO:0048407 8 5 1,000 1,708E-05 0,01038481 ! platelet dense granule GO:0042827 6 5 1,000 1,708E-05 8,901E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 1,000 1,708E-05 7,789E-03 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 1,000 1,708E-05 6,923E-03 GO:0010811|positive regulation of cell-substrate adhesion, ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 1,708E-05 6,231E-03 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 2,000 2,506E-05 8,312E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 2,56E-05 7,782E-03 ! embryonic camera-type eye development GO:0031076 9 6 1,000 2,56E-05 7,184E-03 GO:0048596|embryonic camera-type eye morphogenesis, ! regulation of platelet activation GO:0010543 7 6 1,000 2,56E-05 6,67E-03 ! MutLalpha complex binding GO:0032405 8 6 1,000 2,56E-05 6,226E-03 ! regulation of focal adhesion formation GO:0051893 6 6 1,000 2,56E-05 5,837E-03 ! DNA replication factor C complex GO:0005663 7 6 1,000 2,56E-05 5,493E-03 ! chromatin assembly complex GO:0005678 16 6 1,000 2,56E-05 5,188E-03 ! negative regulation of protein ubiquitination GO:0031397 7 6 1,000 2,56E-05 4,915E-03 ! nucleobase transmembrane transporter activity GO:0015205 7 6 1,000 2,56E-05 4,669E-03 ! embryonic skeletal system development GO:0048706 59 50 2,000 3,956E-05 6,873E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 2,000 4,2E-05 6,964E-03 ! regulation of DNA replication GO:0006275 75 53 2,000 4,716E-05 7,48E-03 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 1,000 4,771E-05 7,252E-03 ! regulation of smooth muscle cell migration GO:0014910 11 8 1,000 4,771E-05 6,961E-03 ! keratinocyte proliferation GO:0043616 9 8 1,000 4,771E-05 6,694E-03 ! positive regulation of endothelial cell migration GO:0010595 9 8 1,000 4,771E-05 6,446E-03 ! mismatch repair complex binding GO:0032404 10 8 1,000 4,771E-05 6,216E-03 ! positive regulation of Rho GTPase activity GO:0032321 11 8 1,000 4,771E-05 6,001E-03 ! regulation of actin filament bundle formation GO:0032231 13 8 1,000 4,771E-05 5,801E-03 GO:0051492|regulation of stress fiber formation, ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 1,000 6,129E-05 7,212E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 1,000 6,129E-05 6,987E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 2,000 7,554E-05 8,35E-03 ! positive regulation of Ras GTPase activity GO:0032320 14 10 1,000 7,655E-05 8,213E-03 ! trophectodermal cell differentiation GO:0001829 11 10 1,000 7,655E-05 7,978E-03 ! regulation of phosphatase activity GO:0010921 10 10 1,000 7,655E-05 7,757E-03 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 1,000 7,655E-05 7,547E-03 ! embryonic eye morphogenesis GO:0048048 14 10 1,000 7,655E-05 7,349E-03 ! platelet-derived growth factor receptor binding GO:0005161 14 10 1,000 7,655E-05 7,16E-03 ! response to inorganic substance GO:0010035 71 65 2,000 8,701E-05 7,935E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 2,000 8,701E-05 7,742E-03 ! protein kinase regulator activity GO:0019887 74 66 2,000 9,107E-05 7,911E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 1,000 9,348E-05 7,931E-03 ! fibrillar collagen GO:0005583 12 11 1,000 9,348E-05 7,75E-03 ! response to cAMP GO:0051591 11 11 1,000 9,348E-05 7,578E-03 ! substrate-bound cell migration GO:0006929 13 11 1,000 9,348E-05 7,413E-03 ! negative regulation of caspase activity GO:0043154 12 11 1,000 9,348E-05 7,256E-03 ! response to peptide hormone stimulus GO:0043434 79 67 2,000 9,526E-05 7,24E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 2,000 9,526E-05 7,092E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 2,000 9,957E-05 7,265E-03 ! positive regulation of ligase activity GO:0051351 86 70 2,000 1,086E-04 7,766E-03 ! positive regulation of GTPase activity GO:0043547 17 12 1,000 1,121E-04 7,863E-03 ! biomineral formation GO:0031214 14 12 1,000 1,121E-04 7,715E-03 ! blastocyst formation GO:0001825 13 12 1,000 1,121E-04 7,572E-03 ! embryonic placenta development GO:0001892 16 12 1,000 1,121E-04 7,434E-03 ! midbody GO:0030496 14 12 1,000 1,121E-04 7,302E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 2,000 1,333E-04 8,533E-03 ! kinase regulator activity GO:0019207 93 76 2,000 1,387E-04 8,723E-03 ! regulation of ligase activity GO:0051340 95 78 2,000 1,498E-04 9,263E-03 ! negative regulation of peptidase activity GO:0010466 16 14 1,000 1,543E-04 9,381E-03 ! positive regulation of cell growth GO:0030307 15 14 1,000 1,543E-04 9,227E-03 ! release of cytochrome c from mitochondria GO:0001836 26 14 1,000 1,543E-04 9,078E-03 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 1,000 1,543E-04 8,934E-03 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 1,000 1,543E-04 8,794E-03 ! ossification GO:0001503 111 82 2,000 1,738E-04 9,754E-03 ! regulation of Rho GTPase activity GO:0032319 18 15 1,000 1,779E-04 9,832E-03 ! negative regulation of blood coagulation GO:0030195 18 15 1,000 1,779E-04 9,685E-03 ! bone development GO:0060348 112 83 2,000 1,802E-04 9,665E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 2,000 1,802E-04 9,524E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of DNA metabolic process GO:0051052 139 84 2,000 1,867E-04 9,728E-03 ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 1,000 2,031E-04 0,01043662 ! regulation of protein ubiquitination GO:0031396 27 16 1,000 2,031E-04 0,01029166 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 1,000 2,031E-04 0,01015068 ! epidermis morphogenesis GO:0048730 18 16 1,000 2,031E-04 0,01001351 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 1,000 2,031E-04 9,88E-03 ! regulation of dephosphorylation GO:0035303 20 17 1,000 2,3E-04 0,01104095 ! negative regulation of coagulation GO:0050819 20 17 1,000 2,3E-04 0,01089757 ! positive regulation of cell size GO:0045793 19 18 1,000 2,586E-04 0,01209268 ! spindle microtubule GO:0005876 27 18 1,000 2,586E-04 0,01193961 ! embryonic organ morphogenesis GO:0048562 22 18 1,000 2,586E-04 0,01179036 ! negative regulation of translation GO:0017148 31 18 1,000 2,586E-04 0,0116448 ! cellular response to unfolded protein GO:0034620 21 19 1,000 2,887E-04 0,01284554 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of endothelial cell migration GO:0010594 22 19 1,000 2,887E-04 0,01269078 ! positive regulation of locomotion GO:0040017 21 19 1,000 2,887E-04 0,0125397 GO:0050921|positive regulation of chemotaxis, ! positive regulation of fibroblast proliferation GO:0048146 25 19 1,000 2,887E-04 0,01239217 ! chaperone binding GO:0051087 21 20 1,000 3,206E-04 0,01359784 ! negative regulation of lipid metabolic process GO:0045833 34 20 1,000 3,206E-04 0,01344154 ! nuclear inner membrane GO:0005637 21 20 1,000 3,206E-04 0,01328879 ! regulation of chemotaxis GO:0050920 22 20 1,000 3,206E-04 0,01313948 ! regulation of cell-matrix adhesion GO:0001952 26 20 1,000 3,206E-04 0,01299349 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of DNA replication GO:0045740 27 21 1,000 3,54E-04 0,01419179 ! apoptotic mitochondrial changes GO:0008637 33 21 1,000 3,54E-04 0,01403753 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 1,000 3,891E-04 0,01526275 ! response to corticosteroid stimulus GO:0031960 25 22 1,000 3,891E-04 0,01510038 ! collagen fibril organization GO:0030199 32 22 1,000 3,891E-04 0,01494142 ! positive regulation of behavior GO:0048520 24 22 1,000 3,891E-04 0,01478579 ! base-excision repair GO:0006284 33 22 1,000 3,891E-04 0,01463335 ! regulation of blood coagulation GO:0030193 26 23 1,000 4,258E-04 0,01585049 ! cell surface binding GO:0043498 28 23 1,000 4,258E-04 0,01569038 ! growth cone GO:0030426 27 24 1,000 4,641E-04 0,01693175 ! actin filament GO:0005884 26 24 1,000 4,641E-04 0,01676411 ! site of polarized growth GO:0030427 28 25 1,000 5,041E-04 0,01802845 ! regulation of lipid biosynthetic process GO:0046890 35 25 1,000 5,041E-04 0,01785342 ! regulation of behavior GO:0050795 27 25 1,000 5,041E-04 0,01768175 ! regulation of coagulation GO:0050818 28 25 1,000 5,041E-04 0,01751335 ! collagen metabolic process GO:0032963 26 25 1,000 5,041E-04 0,01734813 ! regulation of endothelial cell proliferation GO:0001936 29 25 1,000 5,041E-04 0,017186 ! positive regulation of cell adhesion GO:0045785 34 26 1,000 5,456E-04 0,01843069 ! blastocyst development GO:0001824 27 26 1,000 5,456E-04 0,0182616 ! regulation of fibroblast proliferation GO:0048145 32 26 1,000 5,456E-04 0,01809558 ! response to endoplasmic reticulum stress GO:0034976 30 26 1,000 5,456E-04 0,01793256 ! RNA export from nucleus GO:0006405 31 27 1,000 5,888E-04 0,01917854 ! collagen binding GO:0005518 29 27 1,000 5,888E-04 0,01900882 ! liver development GO:0001889 33 27 1,000 5,888E-04 0,01884208 ! fat cell differentiation GO:0045444 30 27 1,000 5,888E-04 0,01867823 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 5,888E-04 0,01851722 ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 1,000 5,888E-04 0,01835895 ! response to hydrogen peroxide GO:0042542 32 29 1,000 6,8E-04 0,02102132 ! erythrocyte differentiation GO:0030218 35 29 1,000 6,8E-04 0,02084467 ! replication fork GO:0005657 42 29 1,000 6,8E-04 0,02067096 ! camera-type eye morphogenesis GO:0048593 36 29 1,000 6,8E-04 0,02050013 ! ER-nuclear signaling pathway GO:0006984 32 29 1,000 6,8E-04 0,02033209 ! response to mechanical stimulus GO:0009612 33 29 1,000 6,8E-04 0,02016679 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 1,000 7,279E-04 0,0214155 ! mitochondrial nucleoid GO:0042645 44 30 1,000 7,279E-04 0,02124417 GO:0009295|nucleoid, ! negative regulation of protein modification process GO:0031400 34 30 1,000 7,279E-04 0,02107557 ! response to calcium ion GO:0051592 34 31 1,000 7,775E-04 0,02233338 ! multicellular organismal metabolic process GO:0044236 35 32 1,000 8,287E-04 0,02361684 ! embryonic organ development GO:0048568 41 33 1,000 8,814E-04 0,02492522 ! placenta development GO:0001890 39 33 1,000 8,814E-04 0,02473349 ! odontogenesis GO:0042476 39 34 1,000 9,357E-04 0,0260574 ! negative regulation of hydrolase activity GO:0051346 36 34 1,000 9,357E-04 0,02586 ! cell growth GO:0016049 36 34 1,000 9,357E-04 0,02566556 ! erythrocyte homeostasis GO:0034101 40 34 1,000 9,357E-04 0,02547403 ! protein kinase inhibitor activity GO:0004860 37 34 1,000 9,357E-04 0,02528533 ! positive regulation of DNA metabolic process GO:0051054 53 35 1,000 9,916E-04 0,02659882 ! vesicle lumen GO:0031983 38 35 1,000 9,916E-04 0,02640467 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! kinase inhibitor activity GO:0019210 47 35 1,000 9,916E-04 0,02621333 ! collagen GO:0005581 54 35 1,000 9,916E-04 0,02602475 ! negative regulation of cell activation GO:0050866 40 36 1,000 1,049E-03 0,02733643 ! positive regulation of response to external stimulus GO:0032103 42 40 1,000 1,295E-03 0,03349533 ! induction of apoptosis by intracellular signals GO:0008629 56 41 1,000 1,36E-03 0,03493649 ! lamellipodium GO:0030027 56 41 1,000 1,36E-03 0,03469217 ! response to reactive oxygen species GO:0000302 49 42 1,000 1,427E-03 0,03614426 ! nuclear export GO:0051168 46 42 1,000 1,427E-03 0,03589499 ! positive regulation of cell cycle GO:0045787 56 43 1,000 1,495E-03 0,03735756 ! positive regulation of growth GO:0045927 47 43 1,000 1,495E-03 0,03710343 ! negative regulation of cell migration GO:0030336 53 44 1,000 1,565E-03 0,03857608 ! response to UV GO:0009411 59 45 1,000 1,636E-03 0,04006661 ! eye morphogenesis GO:0048592 57 46 1,000 1,709E-03 0,04157458 ! response to insulin stimulus GO:0032868 57 47 1,000 1,784E-03 0,04309954 ! growth factor receptor binding GO:0070851 58 48 1,000 1,86E-03 0,04464106 ! protein N-terminus binding GO:0047485 57 48 1,000 1,86E-03 0,04434928 ! negative regulation of cell motion GO:0051271 60 49 1,000 1,938E-03 0,04589873 ! nuclear periphery GO:0034399 60 49 1,000 1,938E-03 0,04560261 ! nucleotide-excision repair GO:0006289 53 49 1,000 1,938E-03 0,04531029 ! DNA damage response, signal transduction GO:0042770 84 50 1,000 2,017E-03 0,04685928 ! positive regulation of cell migration GO:0030335 63 51 1,000 2,097E-03 0,04842365 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 1,000 2,097E-03 0,04811909 ! keratinocyte differentiation GO:0030216 60 53 1,000 2,263E-03 0,05159695 ! double-stranded DNA binding GO:0003690 63 54 1,000 2,348E-03 0,05320517 ! extracellular matrix organization GO:0030198 77 55 1,000 2,435E-03 0,05482729 ! positive regulation of cell motion GO:0051272 69 55 1,000 2,435E-03 0,05449092 ! epidermal cell differentiation GO:0009913 66 58 1,000 2,704E-03 0,06013817 ! response to nutrient GO:0007584 68 58 1,000 2,704E-03 0,0597737 ! response to steroid hormone stimulus GO:0048545 74 59 1,000 2,796E-03 0,06144811 ! cell projection assembly GO:0030031 79 59 1,000 2,796E-03 0,06108015 ! homeostasis of number of cells GO:0048872 67 59 1,000 2,796E-03 0,06071658 ! response to metal ion GO:0010038 65 60 1,000 2,89E-03 0,06238763 ! regulation of caspase activity GO:0043281 78 60 1,000 2,89E-03 0,06202065 ! camera-type eye development GO:0043010 69 61 1,000 2,986E-03 0,06369603 ! lung development GO:0030324 90 62 1,000 3,083E-03 0,06538315 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 1,000 3,083E-03 0,06500522 ! regulation of endopeptidase activity GO:0052548 81 63 1,000 3,181E-03 0,06669622 ! negative regulation of protein kinase activity GO:0006469 78 64 1,000 3,281E-03 0,06839844 ! respiratory tube development GO:0030323 92 64 1,000 3,281E-03 0,06800981 ! regulation of actin cytoskeleton organization GO:0032956 93 64 1,000 3,281E-03 0,06762557 ! response to unfolded protein GO:0006986 66 64 1,000 3,281E-03 0,06724565 ! multicellular organism reproduction GO:0032504 71 65 1,000 3,383E-03 0,06893654 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of kinase activity GO:0033673 79 65 1,000 3,383E-03 0,06855356 ! myeloid cell differentiation GO:0030099 78 66 1,000 3,485E-03 0,07024791 ! regulation of peptidase activity GO:0052547 86 67 1,000 3,59E-03 0,07195278 ! regulation of actin filament-based process GO:0032970 96 67 1,000 3,59E-03 0,0715596 ! female pregnancy GO:0007565 78 67 1,000 3,59E-03 0,07117069 ! respiratory system development GO:0060541 96 68 1,000 3,696E-03 0,07287151 ! nucleosome assembly GO:0006334 87 69 1,000 3,803E-03 0,07458241 ! negative regulation of transferase activity GO:0051348 85 70 1,000 3,911E-03 0,07630316 ! chromatin assembly GO:0031497 88 70 1,000 3,911E-03 0,07589729 ! positive regulation of phosphorylation GO:0042327 82 70 1,000 3,911E-03 0,07549572 ! response to protein stimulus GO:0051789 73 70 1,000 3,911E-03 0,07509837 ! cell cortex GO:0005938 77 70 1,000 3,911E-03 0,07470519 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 1,000 4,133E-03 0,0785268 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 84 72 1,000 4,133E-03 0,07811992 ! regulation of Rho protein signal transduction GO:0035023 88 73 1,000 4,246E-03 0,07984129 ! response to oxygen levels GO:0070482 86 74 1,000 4,36E-03 0,08157172 ! protein-DNA complex assembly GO:0065004 101 74 1,000 4,36E-03 0,08115554 ! phosphoinositide-mediated signaling GO:0048015 92 74 1,000 4,36E-03 0,08074358 ! regulation of lipid metabolic process GO:0019216 98 76 1,000 4,593E-03 0,0846293 ! cell leading edge GO:0031252 97 76 1,000 4,593E-03 0,08420403 ! nucleosome organization GO:0034728 96 77 1,000 4,712E-03 0,08594709 ! regulation of Ras GTPase activity GO:0032318 88 77 1,000 4,712E-03 0,0855195 ! establishment of RNA localization GO:0051236 97 77 1,000 4,712E-03 0,08509613 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! positive regulation of protein modification process GO:0031401 100 78 1,000 4,832E-03 0,08683443 ! extracellular matrix structural constituent GO:0005201 96 78 1,000 4,832E-03 0,08640877 ! RNA localization GO:0006403 99 79 1,000 4,954E-03 0,08814878 ! positive regulation of MAP kinase activity GO:0043406 89 79 1,000 4,954E-03 0,08772087 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 1,000 5,076E-03 0,0894625 ! eye development GO:0001654 93 80 1,000 5,076E-03 0,0890324 ! mitochondrion organization GO:0007005 104 82 1,000 5,326E-03 0,0929691 ! regulation of cell adhesion GO:0030155 98 83 1,000 5,453E-03 0,09473372 ! growth factor binding GO:0019838 102 88 1,000 6,11E-03 0,10562855 ! protein kinase binding GO:0019901 115 89 1,000 6,245E-03 0,10745947 ! negative regulation of multicellular organismal process GO:0051241 102 90 1,000 6,382E-03 0,10929665 ! extracellular matrix part GO:0044420 111 90 1,000 6,382E-03 0,10878592 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 1,000 6,52E-03 0,11062301 ! spindle GO:0005819 126 92 1,000 6,659E-03 0,1124661 ! structure-specific DNA binding GO:0043566 112 92 1,000 6,659E-03 0,11194782 ! regulation of cellular component biogenesis GO:0044087 115 92 1,000 6,659E-03 0,1114343 ! regulation of GTPase activity GO:0043087 105 92 1,000 6,659E-03 0,11092547 ! extracellular structure organization GO:0043062 119 92 1,000 6,659E-03 0,11042126 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 6,66E-03 0,10993932 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 6,66E-03 0,10944409 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 6,66E-03 0,10895331 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 6,66E-03 0,10846691 ! response to superoxide GO:0000303 5 5 0,000 6,66E-03 0,10798484 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 6,66E-03 0,10750703 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 6,66E-03 0,10703343 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 6,66E-03 0,10656399 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 6,66E-03 0,10609864 ! quinolinate metabolic process GO:0046874 5 5 0,000 6,66E-03 0,10563734 ! biotin binding GO:0009374 7 5 0,000 6,66E-03 0,10518004 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 6,66E-03 0,10472668 ! tongue development GO:0043586 6 5 0,000 6,66E-03 0,10427721 ! nose development GO:0043584 5 5 0,000 6,66E-03 0,10383158 ! cell proliferation in forebrain GO:0021846 5 5 0,000 6,66E-03 0,10338974 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 6,66E-03 0,10295165 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 6,66E-03 0,10251725 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 6,66E-03 0,10208651 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 6,66E-03 0,10165937 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 6,66E-03 0,10123579 ! glycolipid transport GO:0046836 6 5 0,000 6,66E-03 0,10081572 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 6,66E-03 0,10039913 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 6,66E-03 0,09998596 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 6,66E-03 0,09957618 ! neuron adhesion GO:0007158 5 5 0,000 6,66E-03 0,09916975 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 6,66E-03 0,09876662 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 6,66E-03 0,09836676 ! opioid peptide activity GO:0001515 6 5 0,000 6,66E-03 0,09797012 ! selenocysteine incorporation GO:0001514 5 5 0,000 6,66E-03 0,09757666 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 6,66E-03 0,09718636 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 6,66E-03 0,09679916 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 6,66E-03 0,09641503 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 6,66E-03 0,09603395 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 6,66E-03 0,09565586 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,66E-03 0,09528074 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 6,66E-03 0,09490855 ! clathrin coat assembly GO:0048268 6 5 0,000 6,66E-03 0,09453926 ! cerebral cortex cell migration GO:0021795 5 5 0,000 6,66E-03 0,09417282 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 6,66E-03 0,09380922 ! membrane hyperpolarization GO:0060081 5 5 0,000 6,66E-03 0,09344842 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 6,66E-03 0,09309038 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 6,66E-03 0,09273507 ! translation repressor activity GO:0030371 8 5 0,000 6,66E-03 0,09238247 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 6,66E-03 0,09203253 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 6,66E-03 0,09168524 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 6,66E-03 0,09134056 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 6,66E-03 0,09099846 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 6,66E-03 0,09065891 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 6,66E-03 0,09032189 ! negative regulation of heart contraction GO:0045822 5 5 0,000 6,66E-03 0,08998737 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 6,66E-03 0,08965531 ! microfibril GO:0001527 5 5 0,000 6,66E-03 0,08932569 ! troponin I binding GO:0031013 5 5 0,000 6,66E-03 0,08899849 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 6,66E-03 0,08867368 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 6,66E-03 0,08835123 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 6,66E-03 0,08803112 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 6,66E-03 0,08771332 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 6,66E-03 0,0873978 ! protein lipoylation GO:0009249 14 5 0,000 6,66E-03 0,08708455 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,66E-03 0,08677353 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 6,66E-03 0,08646473 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 6,66E-03 0,08615812 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 6,66E-03 0,08585367 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 6,66E-03 0,08555137 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 6,66E-03 0,08525119 ! glutamate catabolic process GO:0006538 6 5 0,000 6,66E-03 0,08495311 ! microvillus organization GO:0032528 5 5 0,000 6,66E-03 0,0846571 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 6,66E-03 0,08436316 ! tyrosine catabolic process GO:0006572 5 5 0,000 6,66E-03 0,08407124 ! response to pH GO:0009268 5 5 0,000 6,66E-03 0,08378134 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 6,66E-03 0,08349343 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 6,66E-03 0,0832075 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 6,66E-03 0,08292351 ! polyol biosynthetic process GO:0046173 5 5 0,000 6,66E-03 0,08264146 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 6,66E-03 0,08236132 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,66E-03 0,08208307 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 6,66E-03 0,0818067 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 6,66E-03 0,08153218 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 6,66E-03 0,08125949 ! anaerobic glycolysis GO:0019642 5 5 0,000 6,66E-03 0,08098863 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 6,66E-03 0,08071956 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 6,66E-03 0,08045228 ! peroxisomal matrix GO:0005782 5 5 0,000 6,66E-03 0,08018676 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 6,66E-03 0,07992299 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 6,66E-03 0,07966095 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 6,66E-03 0,07940062 ! multivesicular body GO:0005771 5 5 0,000 6,66E-03 0,07914198 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 6,66E-03 0,07888503 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 6,66E-03 0,07862974 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 6,66E-03 0,07837609 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 6,66E-03 0,07812408 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 6,66E-03 0,07787368 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 6,66E-03 0,07762488 ! epithelial cell maturation GO:0002070 14 5 0,000 6,66E-03 0,07737767 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 6,66E-03 0,07713203 ! muscle thin filament assembly GO:0030240 5 5 0,000 6,66E-03 0,07688794 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 6,66E-03 0,07664539 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 6,66E-03 0,07640437 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 0,000 6,66E-03 0,07616486 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 6,66E-03 0,07592684 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,66E-03 0,07569031 ! positive regulation of translational initiation GO:0045948 6 5 0,000 6,66E-03 0,07545524 ! nonhomologous end joining complex GO:0070419 6 5 0,000 6,66E-03 0,07522164 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 6,66E-03 0,07498947 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 6,66E-03 0,07475873 ! ATPase activator activity GO:0001671 5 5 0,000 6,66E-03 0,07452941 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 6,66E-03 0,07430149 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 0,000 6,66E-03 0,07407497 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 6,66E-03 0,07384981 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 6,66E-03 0,07362603 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 6,66E-03 0,07340359 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 6,66E-03 0,0731825 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 6,66E-03 0,07296273 ! cardiac myofibril assembly GO:0055003 5 5 0,000 6,66E-03 0,07274428 ! anterograde axon cargo transport GO:0008089 6 5 0,000 6,66E-03 0,07252713 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,66E-03 0,07231128 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 6,66E-03 0,0720967 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 6,66E-03 0,0718834 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 6,66E-03 0,07167135 ! protein localization to telomere GO:0070198 7 5 0,000 6,66E-03 0,07146056 ! response to exogenous dsRNA GO:0043330 5 5 0,000 6,66E-03 0,07125099 ! MutSalpha complex binding GO:0032407 7 5 0,000 6,66E-03 0,07104266 ! bile acid biosynthetic process GO:0006699 5 5 0,000 6,66E-03 0,07083554 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 6,66E-03 0,07062962 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,66E-03 0,0704249 ! nerve growth factor binding GO:0048406 7 5 0,000 6,66E-03 0,07022135 ! high-density lipoprotein binding GO:0008035 6 5 0,000 6,66E-03 0,07001899 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 6,66E-03 0,06981778 ! transcription initiation factor activity GO:0016986 5 5 0,000 6,66E-03 0,06961773 ! gas homeostasis GO:0033483 5 5 0,000 6,66E-03 0,06941883 ! Schwann cell development GO:0014044 5 5 0,000 6,66E-03 0,06922105 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 6,66E-03 0,0690244 ! cyclohydrolase activity GO:0019238 5 5 0,000 6,66E-03 0,06882886 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 6,66E-03 0,06863443 ! response to pheromone GO:0019236 5 5 0,000 6,66E-03 0,0684411 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 6,66E-03 0,06824884 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 6,66E-03 0,06805767 ! rhombomere development GO:0021546 6 5 0,000 6,66E-03 0,06786757 ! alanine transport GO:0032328 6 5 0,000 6,66E-03 0,06767852 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 6,66E-03 0,06749052 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 6,66E-03 0,06730357 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 6,66E-03 0,06711765 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 6,66E-03 0,06693275 ! regulation of meiosis GO:0040020 6 5 0,000 6,66E-03 0,06674887 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 6,66E-03 0,066566 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 6,66E-03 0,06638412 ! lymphocyte costimulation GO:0031294 5 5 0,000 6,66E-03 0,06620324 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 6,66E-03 0,06602334 ! RS domain binding GO:0050733 6 5 0,000 6,66E-03 0,06584441 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 6,66E-03 0,06566646 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 6,66E-03 0,06548946 ! B cell homeostasis GO:0001782 6 5 0,000 6,66E-03 0,06531341 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 6,66E-03 0,06513831 ! anaphase GO:0051322 7 5 0,000 6,66E-03 0,06496414 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 6,66E-03 0,0647909 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 6,66E-03 0,06461859 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 6,66E-03 0,06444719 ! AP-2 adaptor complex GO:0030122 5 5 0,000 6,66E-03 0,06427669 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 6,66E-03 0,06410709 ! diuresis GO:0030146 5 5 0,000 6,66E-03 0,06393839 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 6,66E-03 0,06377057 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 6,66E-03 0,06360364 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 6,66E-03 0,06343757 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 6,66E-03 0,06327237 ! GTP-Rho binding GO:0017049 5 5 0,000 6,66E-03 0,06310802 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 6,66E-03 0,06294453 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,66E-03 0,06278188 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 6,66E-03 0,06262007 ! brown fat cell differentiation GO:0050873 5 5 0,000 6,66E-03 0,0624591 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,66E-03 0,06229895 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 6,66E-03 0,06213961 ! TAP complex GO:0042825 5 5 0,000 6,66E-03 0,06198109 ! bHLH transcription factor binding GO:0043425 5 5 0,000 6,66E-03 0,06182338 ! secretory granule organization GO:0033363 5 5 0,000 6,66E-03 0,06166647 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 6,66E-03 0,06151035 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 6,66E-03 0,06135502 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 6,66E-03 0,06120048 ! lamin binding GO:0005521 8 5 0,000 6,66E-03 0,06104671 ! aldehyde-lyase activity GO:0016832 6 5 0,000 6,66E-03 0,06089371 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,66E-03 0,06074147 ! neural plate morphogenesis GO:0001839 6 5 0,000 6,66E-03 0,06059 ! cyclosporin A binding GO:0016018 6 5 0,000 6,66E-03 0,06043928 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 6,66E-03 0,0602893 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 6,66E-03 0,06014007 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 6,66E-03 0,05999158 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 6,66E-03 0,05984381 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 6,66E-03 0,05969678 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 6,66E-03 0,05955046 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 6,66E-03 0,05940486 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 6,66E-03 0,05925997 ! organ or tissue specific immune response GO:0002251 6 5 0,000 6,66E-03 0,05911579 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 6,66E-03 0,0589723 ! retina homeostasis GO:0001895 5 5 0,000 6,66E-03 0,05882951 ! prepulse inhibition GO:0060134 8 5 0,000 6,66E-03 0,05868741 ! maternal placenta development GO:0001893 5 5 0,000 6,66E-03 0,058546 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 6,66E-03 0,05840526 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 6,66E-03 0,0582652 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 6,66E-03 0,05812581 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 6,66E-03 0,05798709 ! protein palmitoylation GO:0018345 5 5 0,000 6,66E-03 0,05784902 ! protein amino acid prenylation GO:0018346 6 5 0,000 6,66E-03 0,05771161 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 6,66E-03 0,05757486 ! stem cell division GO:0017145 6 5 0,000 6,66E-03 0,05743874 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 6,66E-03 0,05730328 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 6,66E-03 0,05716844 ! organ regeneration GO:0031100 6 5 0,000 6,66E-03 0,05703425 ! lymphocyte apoptosis GO:0070227 6 5 0,000 6,66E-03 0,05690068 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 6,66E-03 0,05676773 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 6,66E-03 0,05663541 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 6,66E-03 0,05650369 ! acyl carrier activity GO:0000036 5 5 0,000 6,66E-03 0,0563726 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 6,66E-03 0,0562421 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 6,66E-03 0,05611221 ! phagocytic vesicle GO:0045335 5 5 0,000 6,66E-03 0,05598292 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 6,66E-03 0,05585423 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 6,66E-03 0,05572612 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 6,66E-03 0,0555986 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 6,66E-03 0,05547166 ! polyol transport GO:0015791 8 5 0,000 6,66E-03 0,0553453 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 6,66E-03 0,05521952 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 6,66E-03 0,05509431 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 6,66E-03 0,05496966 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 6,66E-03 0,05484557 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 6,66E-03 0,05472205 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 6,66E-03 0,05459908 ! ethanol metabolic process GO:0006067 6 5 0,000 6,66E-03 0,05447666 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 6,66E-03 0,05435478 ! cobalt ion transport GO:0006824 5 5 0,000 6,66E-03 0,05423346 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 6,66E-03 0,05411267 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 6,66E-03 0,05399242 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 6,66E-03 0,0538727 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 6,66E-03 0,05375352 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 6,66E-03 0,05363485 ! sterol carrier activity GO:0005498 6 5 0,000 6,66E-03 0,05351672 ! adaptation of signaling pathway GO:0022401 6 5 0,000 6,66E-03 0,0533991 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 6,66E-03 0,05328199 ! response to acid GO:0001101 7 5 0,000 6,66E-03 0,0531654 ! fibril organization GO:0043206 5 5 0,000 6,66E-03 0,05304932 ! malate metabolic process GO:0006108 6 5 0,000 6,66E-03 0,05293374 ! regulation of dopamine uptake GO:0051584 7 5 0,000 6,66E-03 0,05281867 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 6,66E-03 0,0527041 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 6,66E-03 0,05259002 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 6,66E-03 0,05247643 ! protein maturation by protein folding GO:0022417 5 5 0,000 6,66E-03 0,05236334 ! activation of protein kinase B activity GO:0032148 15 5 0,000 6,66E-03 0,05225073 ! origin recognition complex GO:0000808 5 5 0,000 6,66E-03 0,0521386 ! neurexin binding GO:0042043 6 5 0,000 6,66E-03 0,05202696 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 6,66E-03 0,05191579 ! protein amino acid dealkylation GO:0008214 5 5 0,000 6,66E-03 0,05180509 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 6,66E-03 0,05169487 ! lipoic acid binding GO:0031405 5 5 0,000 6,66E-03 0,05158511 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 6,66E-03 0,05147582 ! lithium ion binding GO:0031403 6 5 0,000 6,66E-03 0,051367 ! grooming behavior GO:0007625 7 5 0,000 6,66E-03 0,05125863 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 6,66E-03 0,05115071 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 6,66E-03 0,05104325 ! lymph vessel development GO:0001945 6 5 0,000 6,66E-03 0,05093624 ! bicarbonate transport GO:0015701 5 5 0,000 6,66E-03 0,05082968 ! response to interferon-gamma GO:0034341 6 5 0,000 6,66E-03 0,05072357 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 6,66E-03 0,05061789 ! endothelial cell proliferation GO:0001935 8 5 0,000 6,66E-03 0,05051266 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 6,66E-03 0,05040786 ! dorsal spinal cord development GO:0021516 6 5 0,000 6,66E-03 0,0503035 ! activation of MAPKKK activity GO:0000185 5 5 0,000 6,66E-03 0,05019956 ! synaptic vesicle maturation GO:0016188 6 5 0,000 6,66E-03 0,05009606 ! sphingoid catabolic process GO:0046521 5 5 0,000 6,66E-03 0,04999298 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 6,66E-03 0,04989033 ! neutrophil mediated immunity GO:0002446 5 5 0,000 6,66E-03 0,04978809 ! intercellular canaliculus GO:0046581 5 5 0,000 6,66E-03 0,04968628 ! dopamine binding GO:0035240 7 5 0,000 6,66E-03 0,04958488 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 6,66E-03 0,04948389 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 6,66E-03 0,04938331 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 6,66E-03 0,04928314 ! amine oxidase activity GO:0008131 7 5 0,000 6,66E-03 0,04918338 ! monocyte activation GO:0042117 9 5 0,000 6,66E-03 0,04908402 ! negative regulation of protein binding GO:0032091 5 5 0,000 6,66E-03 0,04898506 ! regulation of response to food GO:0032095 5 5 0,000 6,66E-03 0,0488865 ! response to food GO:0032094 6 5 0,000 6,66E-03 0,04878833 ! positive regulation of protein binding GO:0032092 5 5 0,000 6,66E-03 0,04869056 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 6,66E-03 0,04859318 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 6,66E-03 0,04849619 ! hedgehog receptor activity GO:0008158 5 5 0,000 6,66E-03 0,04839958 ! lipoprotein catabolic process GO:0042159 5 5 0,000 6,66E-03 0,04830336 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 6,66E-03 0,04820752 ! purine salvage GO:0043101 7 5 0,000 6,66E-03 0,04811206 ! small-subunit processome GO:0032040 5 5 0,000 6,66E-03 0,04801697 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 6,66E-03 0,04792227 ! ciliary rootlet GO:0035253 5 5 0,000 6,66E-03 0,04782793 ! myosin heavy chain binding GO:0032036 5 5 0,000 6,66E-03 0,04773397 ! nucleobase transport GO:0015851 5 5 0,000 6,66E-03 0,04764037 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 6,66E-03 0,04754714 ! GPI anchor binding GO:0034235 6 5 0,000 6,66E-03 0,04745428 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,66E-03 0,04736177 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 6,66E-03 0,04726963 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 6,66E-03 0,04717784 ! basic amino acid transport GO:0015802 5 5 0,000 6,66E-03 0,04708641 ! dendritic shaft GO:0043198 5 5 0,000 6,66E-03 0,04699534 ! terminal button GO:0043195 7 5 0,000 6,66E-03 0,04690461 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 6,66E-03 0,04681424 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 6,66E-03 0,04672421 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 6,66E-03 0,04663453 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 6,66E-03 0,04654519 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 6,66E-03 0,04645619 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 6,66E-03 0,04636754 ! response to UV-C GO:0010225 15 5 0,000 6,66E-03 0,04627922 ! positive regulation of organ growth GO:0046622 5 5 0,000 6,66E-03 0,04619123 ! response to arsenic GO:0046685 6 5 0,000 6,66E-03 0,04610358 ! IgE binding GO:0019863 5 5 0,000 6,66E-03 0,04601627 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 6,66E-03 0,04592928 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 6,66E-03 0,04584262 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 6,66E-03 0,04575629 ! response to copper ion GO:0046688 5 5 0,000 6,66E-03 0,04567028 ! response to cadmium ion GO:0046686 5 5 0,000 6,66E-03 0,04558459 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 6,66E-03 0,04549923 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 6,66E-03 0,04541418 ! protein autoprocessing GO:0016540 6 5 0,000 6,66E-03 0,04532946 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 6,66E-03 0,04524504 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 6,66E-03 0,04516095 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 6,66E-03 0,04507716 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 6,66E-03 0,04499368 ! mitotic recombination GO:0006312 15 5 0,000 6,66E-03 0,04491052 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 6,66E-03 0,04482765 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 6,66E-03 0,0447451 ! membrane to membrane docking GO:0022614 5 5 0,000 6,66E-03 0,04466285 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 6,66E-03 0,0445809 ! translation activator activity GO:0008494 5 5 0,000 6,66E-03 0,04449925 ! somatostatin receptor activity GO:0004994 5 5 0,000 6,66E-03 0,0444179 ! melanocortin receptor activity GO:0004977 6 5 0,000 6,66E-03 0,04433684 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 6,66E-03 0,04425608 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 6,66E-03 0,04417562 ! salivary gland morphogenesis GO:0007435 5 5 0,000 6,66E-03 0,04409544 ! galactosidase activity GO:0015925 5 5 0,000 6,66E-03 0,04401556 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 6,66E-03 0,04393597 ! cellular response to nutrient GO:0031670 5 5 0,000 6,66E-03 0,04385666 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 6,66E-03 0,04377764 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 6,66E-03 0,0436989 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 6,66E-03 0,04362045 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 6,66E-03 0,04354227 ! A band GO:0031672 5 5 0,000 6,66E-03 0,04346438 ! heat generation GO:0031649 5 5 0,000 6,66E-03 0,04338677 ! flagellum organization GO:0043064 5 5 0,000 6,66E-03 0,04330943 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 6,66E-03 0,04323236 ! disaccharide metabolic process GO:0005984 6 5 0,000 6,66E-03 0,04315558 ! glycogen catabolic process GO:0005980 16 5 0,000 6,66E-03 0,04307906 ! dopamine biosynthetic process GO:0042416 6 5 0,000 6,66E-03 0,04300281 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 6,66E-03 0,04292684 ! chromocenter GO:0010369 5 5 0,000 6,66E-03 0,04285113 ! glial cell migration GO:0008347 5 5 0,000 6,66E-03 0,04277568 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 6,66E-03 0,04270051 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 6,66E-03 0,04262559 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 6,66E-03 0,04255094 ! growth hormone receptor binding GO:0005131 5 5 0,000 6,66E-03 0,04247655 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 6,66E-03 0,04240242 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 6,66E-03 0,04232855 ! aminomethyltransferase activity GO:0004047 5 5 0,000 6,66E-03 0,04225494 ! aminoacylase activity GO:0004046 5 5 0,000 6,66E-03 0,04218158 ! penetration of zona pellucida GO:0007341 6 5 0,000 6,66E-03 0,04210847 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 6,66E-03 0,04203562 ! nucleus localization GO:0051647 5 5 0,000 6,66E-03 0,04196302 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 6,66E-03 0,04189067 ! carnitine metabolic process GO:0009437 5 5 0,000 6,66E-03 0,04181857 GO:0006577|betaine metabolic process, ! regulation of cytoskeleton organization GO:0051493 133 93 1,000 6,8E-03 0,04262261 ! response to nutrient levels GO:0031667 105 93 1,000 6,8E-03 0,04254951 ! DNA packaging GO:0006323 113 94 1,000 6,942E-03 0,04336471 ! in utero embryonic development GO:0001701 110 96 1,000 7,231E-03 0,04508892 ! regulation of response to external stimulus GO:0032101 109 96 1,000 7,231E-03 0,04501198 ! unfolded protein binding GO:0051082 118 100 1,000 7,823E-03 0,04861978 ! response to light stimulus GO:0009416 131 100 1,000 7,823E-03 0,0485371 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,987E-03 0,04946898 ! regulation of helicase activity GO:0051095 6 6 0,000 7,987E-03 0,04938513 ! response to oxygen radical GO:0000305 6 6 0,000 7,987E-03 0,04930157 ! positive regulation of axon extension GO:0045773 7 6 0,000 7,987E-03 0,04921829 ! forebrain neuron differentiation GO:0021879 6 6 0,000 7,987E-03 0,04913529 ! forebrain regionalization GO:0021871 7 6 0,000 7,987E-03 0,04905257 ! meiotic prophase I GO:0007128 7 6 0,000 7,987E-03 0,04897013 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 7,987E-03 0,04888797 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 7,987E-03 0,04880608 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 7,987E-03 0,04872446 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 7,987E-03 0,04864312 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 7,987E-03 0,04856205 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 7,987E-03 0,04848125 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 7,987E-03 0,04840071 ! protein amino acid sulfation GO:0006477 9 6 0,000 7,987E-03 0,04832045 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 7,987E-03 0,04824045 ! establishment of tissue polarity GO:0007164 8 6 0,000 7,987E-03 0,04816071 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 7,987E-03 0,04808124 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 7,987E-03 0,04800203 ! hexokinase activity GO:0004396 7 6 0,000 7,987E-03 0,04792307 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 7,987E-03 0,04784438 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 7,987E-03 0,04776595 ! Notch receptor processing GO:0007220 7 6 0,000 7,987E-03 0,04768777 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 7,987E-03 0,04760985 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 7,987E-03 0,04753218 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 7,987E-03 0,04745477 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 7,987E-03 0,04737761 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 7,987E-03 0,0473007 ! neurofilament GO:0005883 7 6 0,000 7,987E-03 0,04722403 ! glial cell fate commitment GO:0021781 7 6 0,000 7,987E-03 0,04714762 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 7,987E-03 0,04707145 ! dynactin complex GO:0005869 7 6 0,000 7,987E-03 0,04699553 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 7,987E-03 0,04691985 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 7,987E-03 0,04684442 ! oocyte maturation GO:0001556 6 6 0,000 7,987E-03 0,04676923 ! DNA replication origin binding GO:0003688 6 6 0,000 7,987E-03 0,04669428 ! reflex GO:0060004 10 6 0,000 7,987E-03 0,04661957 ! positive regulation of glycolysis GO:0045821 6 6 0,000 7,987E-03 0,04654509 ! parathyroid gland development GO:0060017 6 6 0,000 7,987E-03 0,04647086 ! anagen GO:0042640 7 6 0,000 7,987E-03 0,04639686 ! protein-cofactor linkage GO:0018065 15 6 0,000 7,987E-03 0,0463231 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 7,987E-03 0,04624957 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 7,987E-03 0,04617627 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 7,987E-03 0,04610321 ! skeletal myofibril assembly GO:0014866 6 6 0,000 7,987E-03 0,04603038 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 7,987E-03 0,04595777 ! cysteine metabolic process GO:0006534 7 6 0,000 7,987E-03 0,0458854 ! glycine catabolic process GO:0006546 6 6 0,000 7,987E-03 0,04581325 ! adenohypophysis development GO:0021984 6 6 0,000 7,987E-03 0,04574133 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 7,987E-03 0,04566964 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 7,987E-03 0,04559817 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 7,987E-03 0,04552692 ! microtubule nucleation GO:0007020 7 6 0,000 7,987E-03 0,0454559 ! proline biosynthetic process GO:0006561 8 6 0,000 7,987E-03 0,04538509 ! tryptophan metabolic process GO:0006568 6 6 0,000 7,987E-03 0,04531451 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 7,987E-03 0,04524414 ! thyroid hormone generation GO:0006590 6 6 0,000 7,987E-03 0,045174 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 7,987E-03 0,04510407 ! retinoid X receptor binding GO:0046965 7 6 0,000 7,987E-03 0,04503436 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 7,987E-03 0,04496486 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 7,987E-03 0,04489558 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 7,987E-03 0,04482651 ! sister chromatid cohesion GO:0007062 6 6 0,000 7,987E-03 0,04475765 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 7,987E-03 0,044689 ! positive regulation of transporter activity GO:0032411 8 6 0,000 7,987E-03 0,04462057 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 7,987E-03 0,04455234 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 7,987E-03 0,04448432 ! p53 binding GO:0002039 6 6 0,000 7,987E-03 0,04441651 ! demethylase activity GO:0032451 6 6 0,000 7,987E-03 0,0443489 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 7,987E-03 0,0442815 ! lipid phosphatase activity GO:0042577 7 6 0,000 7,987E-03 0,04421431 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 7,987E-03 0,04414732 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 7,987E-03 0,04408053 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 7,987E-03 0,04401394 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 7,987E-03 0,04394756 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 7,987E-03 0,04388137 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 7,987E-03 0,04381538 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 7,987E-03 0,04374959 ! LIM domain binding GO:0030274 7 6 0,000 7,987E-03 0,043684 ! negative regulation of translational initiation GO:0045947 6 6 0,000 7,987E-03 0,04361861 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 7,987E-03 0,04355341 ! 5S class rRNA transcription GO:0042791 6 6 0,000 7,987E-03 0,0434884 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 7,987E-03 0,04342359 ! axon guidance receptor activity GO:0008046 6 6 0,000 7,987E-03 0,04335897 ! zinc ion homeostasis GO:0055069 7 6 0,000 7,987E-03 0,04329455 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 7,987E-03 0,04323031 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 7,987E-03 0,04316627 ! protein targeting to lysosome GO:0006622 6 6 0,000 7,987E-03 0,04310241 ! hyaluronan metabolic process GO:0030212 8 6 0,000 7,987E-03 0,04303874 ! protein retention in ER lumen GO:0006621 6 6 0,000 7,987E-03 0,04297526 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 7,987E-03 0,04291197 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 7,987E-03 0,04284887 ! dynein binding GO:0045502 6 6 0,000 7,987E-03 0,04278595 ! regulation of dendrite development GO:0050773 6 6 0,000 7,987E-03 0,04272321 ! peptidyl-arginine modification GO:0018195 6 6 0,000 7,987E-03 0,04266066 ! eating behavior GO:0042755 7 6 0,000 7,987E-03 0,04259829 ! protein localization to chromosome GO:0034502 8 6 0,000 7,987E-03 0,0425361 ! Hsp90 protein binding GO:0051879 7 6 0,000 7,987E-03 0,0424741 ! glycolipid binding GO:0051861 7 6 0,000 7,987E-03 0,04241227 ! mast cell activation GO:0045576 6 6 0,000 7,987E-03 0,04235062 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,987E-03 0,04228916 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 7,987E-03 0,04222787 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 7,987E-03 0,04216676 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 7,987E-03 0,04210582 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 7,987E-03 0,04204506 ! lipoxygenase activity GO:0016165 6 6 0,000 7,987E-03 0,04198448 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 7,987E-03 0,04192407 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 7,987E-03 0,04186384 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 7,987E-03 0,04180377 ! DNA replication factor A complex GO:0005662 7 6 0,000 7,987E-03 0,04174388 ! establishment of chromosome localization GO:0051303 15 6 0,000 7,987E-03 0,04168416 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 7,987E-03 0,04162461 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 7,987E-03 0,04156523 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 7,987E-03 0,04150602 ! sex chromatin GO:0001739 6 6 0,000 7,987E-03 0,04144698 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 7,987E-03 0,04138811 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 7,987E-03 0,0413294 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 7,987E-03 0,04127086 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 7,987E-03 0,04121249 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 7,987E-03 0,04115428 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 7,987E-03 0,04109623 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 7,987E-03 0,04103835 ! phosphatidylserine binding GO:0001786 6 6 0,000 7,987E-03 0,04098063 ! alpha-mannosidase activity GO:0004559 8 6 0,000 7,987E-03 0,04092307 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 7,987E-03 0,04086568 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 7,987E-03 0,04080844 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 7,987E-03 0,04075137 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 7,987E-03 0,04069445 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 7,987E-03 0,0406377 ! leading edge membrane GO:0031256 8 6 0,000 7,987E-03 0,0405811 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 7,987E-03 0,04052466 ! CARD domain binding GO:0050700 6 6 0,000 7,987E-03 0,04046837 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 7,987E-03 0,04041225 ! COPII vesicle coat GO:0030127 7 6 0,000 7,987E-03 0,04035627 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 7,987E-03 0,04030046 ! glutathione biosynthetic process GO:0006750 7 6 0,000 7,987E-03 0,04024479 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 7,987E-03 0,04018928 ! positive regulation of epidermis development GO:0045684 8 6 0,000 7,987E-03 0,04013392 ! proteasome regulator activity GO:0010860 6 6 0,000 7,987E-03 0,04007872 ! ceramidase activity GO:0017040 6 6 0,000 7,987E-03 0,04002367 ! antibiotic transport GO:0042891 7 6 0,000 7,987E-03 0,03996876 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 7,987E-03 0,03991401 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 7,987E-03 0,03985941 ! sodium channel regulator activity GO:0017080 6 6 0,000 7,987E-03 0,03980496 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,987E-03 0,03975065 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 7,987E-03 0,0396965 ! response to fluid shear stress GO:0034405 6 6 0,000 7,987E-03 0,03964249 ! lymph node development GO:0048535 6 6 0,000 7,987E-03 0,03958863 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 7,987E-03 0,03953491 ! triglyceride catabolic process GO:0019433 15 6 0,000 7,987E-03 0,03948134 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 7,987E-03 0,03942792 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 7,987E-03 0,03937463 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 7,987E-03 0,0393215 ! negative regulation of lipase activity GO:0060192 6 6 0,000 7,987E-03 0,0392685 ! activation of innate immune response GO:0002218 6 6 0,000 7,987E-03 0,03921565 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 7,987E-03 0,03916294 ! sarcoglycan complex GO:0016012 8 6 0,000 7,987E-03 0,03911037 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 7,987E-03 0,03905795 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 7,987E-03 0,03900566 ! neural plate development GO:0001840 7 6 0,000 7,987E-03 0,03895352 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 7,987E-03 0,03890151 ! catecholamine transport GO:0051937 6 6 0,000 7,987E-03 0,03884964 ! ether hydrolase activity GO:0016803 7 6 0,000 7,987E-03 0,03879791 ! FACIT collagen GO:0005593 6 6 0,000 7,987E-03 0,03874632 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 7,987E-03 0,03869486 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 7,987E-03 0,03864354 ! collagen type IV GO:0005587 6 6 0,000 7,987E-03 0,03859236 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 7,987E-03 0,03854131 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 7,987E-03 0,0384904 ! drug metabolic process GO:0017144 6 6 0,000 7,987E-03 0,03843962 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 7,987E-03 0,03838897 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 7,987E-03 0,03833846 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 7,987E-03 0,03828808 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 7,987E-03 0,03823783 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 7,987E-03 0,03818772 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 7,987E-03 0,03813773 ! cellular anion homeostasis GO:0030002 6 6 0,000 7,987E-03 0,03808788 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 7,987E-03 0,03803816 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 7,987E-03 0,03798856 ! behavioral response to cocaine GO:0048148 9 6 0,000 7,987E-03 0,0379391 ! translation initiation factor binding GO:0031369 6 6 0,000 7,987E-03 0,03788976 ! nucleotide-sugar transport GO:0015780 6 6 0,000 7,987E-03 0,03784056 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 7,987E-03 0,03779148 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 7,987E-03 0,03774252 ! quaternary ammonium group binding GO:0050997 7 6 0,000 7,987E-03 0,0376937 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 7,987E-03 0,037645 ! reproductive behavior GO:0019098 8 6 0,000 7,987E-03 0,03759642 ! response to growth hormone stimulus GO:0060416 7 6 0,000 7,987E-03 0,03754798 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 7,987E-03 0,03749965 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 7,987E-03 0,03745145 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 7,987E-03 0,03740338 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 7,987E-03 0,03735542 ! induction of positive chemotaxis GO:0050930 7 6 0,000 7,987E-03 0,03730759 ! cohesin complex GO:0008278 6 6 0,000 7,987E-03 0,03725988 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 7,987E-03 0,0372123 ! citrate metabolic process GO:0006101 7 6 0,000 7,987E-03 0,03716483 ! myelin sheath GO:0043209 8 6 0,000 7,987E-03 0,03711749 ! phototransduction, visible light GO:0007603 6 6 0,000 7,987E-03 0,03707027 ! opsonization GO:0008228 7 6 0,000 7,987E-03 0,03702316 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 7,987E-03 0,03697618 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 7,987E-03 0,03692931 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 7,987E-03 0,03688257 ! regulation of potassium ion transport GO:0043266 8 6 0,000 7,987E-03 0,03683594 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 7,987E-03 0,03678943 ! chemoattractant activity GO:0042056 6 6 0,000 7,987E-03 0,03674304 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 7,987E-03 0,03669676 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 7,987E-03 0,0366506 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 7,987E-03 0,03660456 ! leukocyte degranulation GO:0043299 6 6 0,000 7,987E-03 0,03655863 ! bile acid and bile salt transport GO:0015721 7 6 0,000 7,987E-03 0,03651282 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 7,987E-03 0,03646712 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 7,987E-03 0,03642154 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 7,987E-03 0,03637607 ! DNA topoisomerase activity GO:0003916 6 6 0,000 7,987E-03 0,03633071 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 7,987E-03 0,03628547 ! ceramide biosynthetic process GO:0046513 6 6 0,000 7,987E-03 0,03624033 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 7,987E-03 0,03619532 ! activin receptor activity GO:0017002 7 6 0,000 7,987E-03 0,03615041 ! astrocyte differentiation GO:0048708 6 6 0,000 7,987E-03 0,03610561 ! syncytium formation GO:0006949 6 6 0,000 7,987E-03 0,03606093 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 7,987E-03 0,03601635 ! neutrophil activation GO:0042119 6 6 0,000 7,987E-03 0,03597189 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 7,987E-03 0,03592753 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 7,987E-03 0,03588329 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 7,987E-03 0,03583915 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 7,987E-03 0,03579512 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 7,987E-03 0,0357512 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 7,987E-03 0,03570739 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 7,987E-03 0,03566368 ! neuron apoptosis GO:0051402 7 6 0,000 7,987E-03 0,03562008 ! folic acid transport GO:0015884 8 6 0,000 7,987E-03 0,03557659 ! carnitine transport GO:0015879 6 6 0,000 7,987E-03 0,03553321 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 7,987E-03 0,03548993 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 7,987E-03 0,03544675 ! S-methyltransferase activity GO:0008172 6 6 0,000 7,987E-03 0,03540368 ! phospholipase D activity GO:0004630 6 6 0,000 7,987E-03 0,03536072 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 7,987E-03 0,03531785 ! intercalated disc GO:0014704 8 6 0,000 7,987E-03 0,0352751 ! G2/M transition checkpoint GO:0031576 24 6 0,000 7,987E-03 0,03523244 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 7,987E-03 0,03518989 ! IgG binding GO:0019864 6 6 0,000 7,987E-03 0,03514744 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 7,987E-03 0,0351051 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 7,987E-03 0,03506285 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 7,987E-03 0,03502071 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 7,987E-03 0,03497867 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 7,987E-03 0,03493673 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 7,987E-03 0,03489489 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 7,987E-03 0,03485315 ! dendrite morphogenesis GO:0048813 7 6 0,000 7,987E-03 0,0348115 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 7,987E-03 0,03476996 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 7,987E-03 0,03472852 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 7,987E-03 0,03468718 ! nucleosome disassembly GO:0006337 7 6 0,000 7,987E-03 0,03464593 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 7,987E-03 0,03460479 ! regulation of mast cell activation GO:0033003 6 6 0,000 7,987E-03 0,03456374 ! tetracycline transporter activity GO:0008493 7 6 0,000 7,987E-03 0,03452278 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 7,987E-03 0,03448193 ! receptor internalization GO:0031623 8 6 0,000 7,987E-03 0,03444117 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 7,987E-03 0,03440051 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 7,987E-03 0,03435994 ! histamine receptor activity GO:0004969 7 6 0,000 7,987E-03 0,03431947 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 7,987E-03 0,03427909 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 7,987E-03 0,03423881 ! protein deubiquitination GO:0016579 6 6 0,000 7,987E-03 0,03419863 ! axonal fasciculation GO:0007413 7 6 0,000 7,987E-03 0,03415853 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 7,987E-03 0,03411854 ! cytidine deaminase activity GO:0004126 6 6 0,000 7,987E-03 0,03407863 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 7,987E-03 0,03403882 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 7,987E-03 0,0339991 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 7,987E-03 0,03395947 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 7,987E-03 0,03391994 ! glycine binding GO:0016594 9 6 0,000 7,987E-03 0,0338805 ! apical protein localization GO:0045176 7 6 0,000 7,987E-03 0,03384115 ! ankyrin binding GO:0030506 6 6 0,000 7,987E-03 0,03380189 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 7,987E-03 0,03376272 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 7,987E-03 0,03372364 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 7,987E-03 0,03368466 ! progesterone metabolic process GO:0042448 6 6 0,000 7,987E-03 0,03364576 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 7,987E-03 0,03360695 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 7,987E-03 0,03356824 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 7,987E-03 0,03352961 ! ATP catabolic process GO:0006200 6 6 0,000 7,987E-03 0,03349107 ! CoA carboxylase activity GO:0016421 6 6 0,000 7,987E-03 0,03345262 ! determination of adult lifespan GO:0008340 6 6 0,000 7,987E-03 0,03341425 ! S-acyltransferase activity GO:0016417 6 6 0,000 7,987E-03 0,03337598 ! somatic stem cell maintenance GO:0035019 6 6 0,000 7,987E-03 0,03333779 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 7,987E-03 0,03329969 ! IkappaB kinase complex GO:0008385 7 6 0,000 7,987E-03 0,03326168 ! store-operated calcium channel activity GO:0015279 6 6 0,000 7,987E-03 0,03322375 ! alkaline phosphatase activity GO:0004035 7 6 0,000 7,987E-03 0,03318591 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 7,987E-03 0,03314816 ! unconventional myosin complex GO:0016461 8 6 0,000 7,987E-03 0,03311049 ! tRNA transcription GO:0009304 7 7 0,000 9,312E-03 0,03856034 ! respiratory burst GO:0045730 7 7 0,000 9,312E-03 0,03851662 ! telencephalon cell migration GO:0022029 8 7 0,000 9,312E-03 0,038473 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 9,312E-03 0,03842948 ! cation:chloride symporter activity GO:0015377 8 7 0,000 9,312E-03 0,03838606 ! RNA cap binding GO:0000339 8 7 0,000 9,312E-03 0,03834273 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 9,312E-03 0,03829951 ! ephrin receptor binding GO:0046875 9 7 0,000 9,312E-03 0,03825638 ! male meiosis I GO:0007141 7 7 0,000 9,312E-03 0,03821334 ! synapsis GO:0007129 7 7 0,000 9,312E-03 0,03817041 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 9,312E-03 0,03812757 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 9,312E-03 0,03808482 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 9,312E-03 0,03804217 ! signal peptide processing GO:0006465 7 7 0,000 9,312E-03 0,03799962 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 9,312E-03 0,03795716 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 9,312E-03 0,0379148 ! macrophage chemotaxis GO:0048246 7 7 0,000 9,312E-03 0,03787253 ! Golgi cisterna membrane GO:0032580 7 7 0,000 9,312E-03 0,03783036 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 9,312E-03 0,03778828 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 9,312E-03 0,03774629 ! smoothened signaling pathway GO:0007224 8 7 0,000 9,312E-03 0,0377044 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 9,312E-03 0,0376626 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 9,312E-03 0,03762089 ! cytoplasmic microtubule GO:0005881 7 7 0,000 9,312E-03 0,03757927 ! Arp2/3 protein complex GO:0005885 8 7 0,000 9,312E-03 0,03753775 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 9,312E-03 0,03749632 ! ATPase binding GO:0051117 8 7 0,000 9,312E-03 0,03745497 ! positive regulation of isotype switching GO:0045830 7 7 0,000 9,312E-03 0,03741372 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 9,312E-03 0,03737257 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 9,312E-03 0,0373315 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 9,312E-03 0,03729052 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,312E-03 0,03724963 ! thymic T cell selection GO:0045061 16 7 0,000 9,312E-03 0,03720883 ! transepithelial chloride transport GO:0030321 7 7 0,000 9,312E-03 0,03716812 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 9,312E-03 0,0371275 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 9,312E-03 0,03708697 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 9,312E-03 0,03704652 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 9,312E-03 0,03700617 ! melanocyte differentiation GO:0030318 8 7 0,000 9,312E-03 0,0369659 ! malate dehydrogenase activity GO:0016615 8 7 0,000 9,312E-03 0,03692572 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 9,312E-03 0,03688563 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 9,312E-03 0,03684562 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 9,312E-03 0,0368057 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 9,312E-03 0,03676587 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 9,312E-03 0,03672612 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 9,312E-03 0,03668646 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 9,312E-03 0,03664688 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 9,312E-03 0,03660739 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 9,312E-03 0,03656799 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 9,312E-03 0,03652867 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 9,312E-03 0,03648943 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 9,312E-03 0,03645028 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 9,312E-03 0,03641121 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 9,312E-03 0,03637223 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 9,312E-03 0,03633333 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 9,312E-03 0,03629451 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 9,312E-03 0,03625578 ! melanosome organization GO:0032438 7 7 0,000 9,312E-03 0,03621712 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 9,312E-03 0,03617855 ! mesodermal cell differentiation GO:0048333 9 7 0,000 9,312E-03 0,03614007 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 9,312E-03 0,03610166 ! Rac protein signal transduction GO:0016601 7 7 0,000 9,312E-03 0,03606334 ! chondrocyte differentiation GO:0002062 7 7 0,000 9,312E-03 0,03602509 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 9,312E-03 0,03598693 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 9,312E-03 0,03594885 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 9,312E-03 0,03591085 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 9,312E-03 0,03587293 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 9,312E-03 0,03583509 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 9,312E-03 0,03579733 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 9,312E-03 0,03575964 ! Schwann cell differentiation GO:0014037 8 7 0,000 9,312E-03 0,03572204 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 9,312E-03 0,03568452 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 9,312E-03 0,03564707 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 9,312E-03 0,03560971 ! vinculin binding GO:0017166 9 7 0,000 9,312E-03 0,03557242 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 9,312E-03 0,03553521 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 9,312E-03 0,03549808 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 9,312E-03 0,03546102 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 9,312E-03 0,03542405 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 9,312E-03 0,03538715 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 9,312E-03 0,03535032 ! cardiac muscle cell development GO:0055013 8 7 0,000 9,312E-03 0,03531358 ! fibrinolysis GO:0042730 9 7 0,000 9,312E-03 0,03527691 ! response to tropane GO:0014073 10 7 0,000 9,312E-03 0,03524031 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 9,312E-03 0,03520379 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 9,312E-03 0,03516735 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 9,312E-03 0,03513098 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 9,312E-03 0,03509469 ! laminin-1 complex GO:0005606 7 7 0,000 9,312E-03 0,03505847 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 9,312E-03 0,03502233 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 9,312E-03 0,03498626 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 9,312E-03 0,03495027 ! regulation of cell division GO:0051302 7 7 0,000 9,312E-03 0,03491435 ! holo TFIIH complex GO:0005675 7 7 0,000 9,312E-03 0,0348785 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 9,312E-03 0,03484273 ! chitinase activity GO:0004568 7 7 0,000 9,312E-03 0,03480703 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 9,312E-03 0,0347714 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 9,312E-03 0,03473585 ! regulation of respiratory burst GO:0060263 8 7 0,000 9,312E-03 0,03470037 ! prophase GO:0051324 8 7 0,000 9,312E-03 0,03466496 ! peptidyl-histidine modification GO:0018202 8 7 0,000 9,312E-03 0,03462962 ! centriolar satellite GO:0034451 10 7 0,000 9,312E-03 0,03459436 ! BBSome GO:0034464 7 7 0,000 9,312E-03 0,03455917 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 9,312E-03 0,03452405 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,312E-03 0,034489 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 9,312E-03 0,03445402 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 9,312E-03 0,03441911 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 9,312E-03 0,03438427 ! regulation of synaptogenesis GO:0051963 7 7 0,000 9,312E-03 0,03434951 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 9,312E-03 0,03431481 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 9,312E-03 0,03428018 ! glycolipid catabolic process GO:0019377 7 7 0,000 9,312E-03 0,03424563 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 9,312E-03 0,03421114 ! circadian behavior GO:0048512 9 7 0,000 9,312E-03 0,03417672 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 9,312E-03 0,03414237 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 9,312E-03 0,03410809 ! striatum development GO:0021756 7 7 0,000 9,312E-03 0,03407388 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 9,312E-03 0,03403974 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 9,312E-03 0,03400567 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 9,312E-03 0,03397166 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 9,312E-03 0,03393772 ! dystroglycan complex GO:0016011 9 7 0,000 9,312E-03 0,03390385 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 9,312E-03 0,03387005 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 9,312E-03 0,03383632 ! peroxiredoxin activity GO:0051920 7 7 0,000 9,312E-03 0,03380265 ! muscle adaptation GO:0043500 7 7 0,000 9,312E-03 0,03376905 ! regulation of muscle adaptation GO:0043502 7 7 0,000 9,312E-03 0,03373551 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 9,312E-03 0,03370205 ! lysogeny GO:0030069 7 7 0,000 9,312E-03 0,03366864 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 9,312E-03 0,03363531 ! sequestering of metal ion GO:0051238 9 7 0,000 9,312E-03 0,03360204 ! membrane attack complex GO:0005579 7 7 0,000 9,312E-03 0,03356884 ! fibrinogen complex GO:0005577 7 7 0,000 9,312E-03 0,0335357 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 9,312E-03 0,03350262 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 9,312E-03 0,03346962 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 9,312E-03 0,03343667 ! GABA receptor binding GO:0050811 8 7 0,000 9,312E-03 0,0334038 ! sheet-forming collagen GO:0030935 7 7 0,000 9,312E-03 0,03337098 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 9,312E-03 0,03333824 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 9,312E-03 0,03330555 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 9,312E-03 0,03327293 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 9,312E-03 0,03324037 ! 7S RNA binding GO:0008312 8 7 0,000 9,312E-03 0,03320788 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 9,312E-03 0,03317545 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 9,312E-03 0,03314308 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 9,312E-03 0,03311078 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 9,312E-03 0,03307854 ! Golgi to endosome transport GO:0006895 8 7 0,000 9,312E-03 0,03304636 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 9,312E-03 0,03301425 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 9,312E-03 0,0329822 ! fibril GO:0043205 7 7 0,000 9,312E-03 0,03295021 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 9,312E-03 0,03291828 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 9,312E-03 0,03288641 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 9,312E-03 0,03285461 ! sensory perception of bitter taste GO:0050913 7 7 0,000 9,312E-03 0,03282286 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 9,312E-03 0,03279118 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 9,312E-03 0,03275956 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 9,312E-03 0,032728 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 9,312E-03 0,0326965 ! equilibrioception GO:0050957 10 7 0,000 9,312E-03 0,03266506 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 9,312E-03 0,03263368 ! titin binding GO:0031432 7 7 0,000 9,312E-03 0,03260236 ! chemosensory behavior GO:0007635 9 7 0,000 9,312E-03 0,0325711 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 9,312E-03 0,03253991 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 9,312E-03 0,03250877 ! cobalamin binding GO:0031419 7 7 0,000 9,312E-03 0,03247769 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 9,312E-03 0,03244667 ! response to axon injury GO:0048678 9 7 0,000 9,312E-03 0,03241571 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 9,312E-03 0,03238481 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 9,312E-03 0,03235396 ! F-actin capping protein complex GO:0008290 8 7 0,000 9,312E-03 0,03232318 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 9,312E-03 0,03229245 ! cGMP-mediated signaling GO:0019934 8 7 0,000 9,312E-03 0,03226179 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 9,312E-03 0,03223118 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 9,312E-03 0,03220063 ! senescence GO:0010149 8 7 0,000 9,312E-03 0,03217013 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 9,312E-03 0,0321397 ! nuclear localization sequence binding GO:0008139 8 7 0,000 9,312E-03 0,03210932 ! galactose metabolic process GO:0006012 8 7 0,000 9,312E-03 0,032079 ! vesicle fusion GO:0006906 8 7 0,000 9,312E-03 0,03204874 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 9,312E-03 0,03201853 ! intracellular pH reduction GO:0051452 7 7 0,000 9,312E-03 0,03198838 ! glycerol ether catabolic process GO:0044269 16 7 0,000 9,312E-03 0,03195829 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 9,312E-03 0,03192825 ! ruffle organization GO:0031529 9 7 0,000 9,312E-03 0,03189827 ! nucleoside transport GO:0015858 8 7 0,000 9,312E-03 0,03186835 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 9,312E-03 0,03183848 ! inclusion body GO:0016234 7 7 0,000 9,312E-03 0,03180867 ! Cajal body GO:0015030 7 7 0,000 9,312E-03 0,03177892 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 9,312E-03 0,03174922 ! rRNA modification GO:0000154 7 7 0,000 9,312E-03 0,03171957 ! PcG protein complex GO:0031519 7 7 0,000 9,312E-03 0,03168998 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 9,312E-03 0,03166045 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 9,312E-03 0,03163097 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 9,312E-03 0,03160155 ! apolipoprotein binding GO:0034185 9 7 0,000 9,312E-03 0,03157218 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 9,312E-03 0,03154286 ! segment specification GO:0007379 9 7 0,000 9,312E-03 0,0315136 ! pronucleus GO:0045120 25 7 0,000 9,312E-03 0,03148439 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 9,312E-03 0,03145524 ! Rac GTPase activator activity GO:0030675 9 7 0,000 9,312E-03 0,03142614 ! regulation of DNA repair GO:0006282 19 7 0,000 9,312E-03 0,0313971 ! preribosome GO:0030684 7 7 0,000 9,312E-03 0,03136811 ! DNA topological change GO:0006265 7 7 0,000 9,312E-03 0,03133917 ! DNA ligation GO:0006266 8 7 0,000 9,312E-03 0,03131029 ! hair follicle maturation GO:0048820 8 7 0,000 9,312E-03 0,03128146 ! renal water homeostasis GO:0003091 7 7 0,000 9,312E-03 0,03125268 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 9,312E-03 0,03122395 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 9,312E-03 0,03119528 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 9,312E-03 0,03116666 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 9,312E-03 0,0311381 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 9,312E-03 0,03110958 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 9,312E-03 0,03108112 ! phosphofructokinase activity GO:0008443 7 7 0,000 9,312E-03 0,03105271 ! gap junction channel activity GO:0005243 8 7 0,000 9,312E-03 0,03102435 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 9,312E-03 0,03099604 ! histone methylation GO:0016571 7 7 0,000 9,312E-03 0,03096779 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 9,312E-03 0,03093958 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 9,312E-03 0,03091143 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 9,312E-03 0,03088333 ! muscle cell proliferation GO:0033002 8 7 0,000 9,312E-03 0,03085528 ! transcription termination GO:0006353 9 7 0,000 9,312E-03 0,03082728 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 0,000 9,312E-03 0,03079933 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 9,312E-03 0,03077143 ! cytidylyltransferase activity GO:0070567 8 7 0,000 9,312E-03 0,03074359 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 9,312E-03 0,03071579 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 9,312E-03 0,03068804 ! salivary gland development GO:0007431 7 7 0,000 9,312E-03 0,03066034 ! glucosidase activity GO:0015926 8 7 0,000 9,312E-03 0,0306327 ! NuRD complex GO:0016581 8 7 0,000 9,312E-03 0,0306051 ! negative regulation of nuclear division GO:0051784 7 7 0,000 9,312E-03 0,03057755 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 9,312E-03 0,03055006 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 9,312E-03 0,03052261 ! response to redox state GO:0051775 8 7 0,000 9,312E-03 0,03049521 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 9,312E-03 0,03046786 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 9,312E-03 0,03044056 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 9,312E-03 0,03041331 ! actin monomer binding GO:0003785 7 7 0,000 9,312E-03 0,0303861 ! protein prenyltransferase activity GO:0008318 8 7 0,000 9,312E-03 0,03035895 ! endosome to lysosome transport GO:0008333 7 7 0,000 9,312E-03 0,03033184 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 9,312E-03 0,03030478 ! germ cell migration GO:0008354 7 7 0,000 9,312E-03 0,03027777 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 9,312E-03 0,03025081 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 9,312E-03 0,0302239 ! CoA-ligase activity GO:0016405 8 7 0,000 9,312E-03 0,03019703 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 9,312E-03 0,03017021 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 9,312E-03 0,03014344 ! embryonic heart tube development GO:0035050 8 7 0,000 9,312E-03 0,03011672 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 9,312E-03 0,03009005 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 9,312E-03 0,03006342 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 9,312E-03 0,03003684 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 9,312E-03 0,0300103 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 9,312E-03 0,02998381 ! adenylate kinase activity GO:0004017 8 7 0,000 9,312E-03 0,02995737 ! negative regulation of immune effector process GO:0002698 13 7 0,000 9,312E-03 0,02993098 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 9,312E-03 0,02990463 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 9,312E-03 0,02987833 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 0,01063594 0,03409481 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 0,01063594 0,03406488 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 0,01063594 0,03403499 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 0,01063594 0,03400517 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 0,01063594 0,03397539 ! proteasome regulatory particle GO:0005838 8 8 0,000 0,01063594 0,03394566 ! SMAD protein complex assembly GO:0007183 10 8 0,000 0,01063594 0,03391599 ! protein self-association GO:0043621 8 8 0,000 0,01063594 0,03388637 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 0,01063594 0,0338568 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 0,01063594 0,03382728 ! neurotransmitter uptake GO:0001504 8 8 0,000 0,01063594 0,03379782 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 0,01063594 0,0337684 ! guanylate cyclase activity GO:0004383 9 8 0,000 0,01063594 0,03373904 ! troponin complex GO:0005861 8 8 0,000 0,01063594 0,03370973 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 0,01063594 0,03368046 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 0,01063594 0,03365125 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 0,01063594 0,03362209 ! microtubule bundle formation GO:0001578 8 8 0,000 0,01063594 0,03359298 ! middle ear morphogenesis GO:0042474 10 8 0,000 0,01063594 0,03356392 ! ganglioside metabolic process GO:0001573 8 8 0,000 0,01063594 0,03353491 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 0,01063594 0,03350595 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 0,01063594 0,03347704 ! ciliary or flagellar motility GO:0001539 8 8 0,000 0,01063594 0,03344818 ! pathogenesis GO:0009405 8 8 0,000 0,01063594 0,03341937 ! pH reduction GO:0045851 9 8 0,000 0,01063594 0,03339061 ! small protein activating enzyme activity GO:0008641 10 8 0,000 0,01063594 0,0333619 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 0,01063594 0,03333324 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 0,01063594 0,03330463 ! hemoglobin metabolic process GO:0020027 8 8 0,000 0,01063594 0,03327607 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 0,01063594 0,03324755 ! arginine catabolic process GO:0006527 9 8 0,000 0,01063594 0,03321909 ! T-tubule GO:0030315 9 8 0,000 0,01063594 0,03319067 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 0,01063594 0,0331623 ! histidine catabolic process GO:0006548 8 8 0,000 0,01063594 0,03313398 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 0,01063594 0,03310571 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 0,01063594 0,03307749 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 0,01063594 0,03304931 ! proline metabolic process GO:0006560 10 8 0,000 0,01063594 0,03302119 ! L-serine metabolic process GO:0006563 9 8 0,000 0,01063594 0,03299311 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 0,01063594 0,03296508 ! melanosome membrane GO:0033162 9 8 0,000 0,01063594 0,03293709 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01063594 0,03290916 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 0,01063594 0,03288127 ! pericentriolar material GO:0000242 9 8 0,000 0,01063594 0,03285342 ! reverse cholesterol transport GO:0043691 8 8 0,000 0,01063594 0,03282563 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 0,01063594 0,03279788 ! melanin metabolic process GO:0006582 10 8 0,000 0,01063594 0,03277018 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 0,01063594 0,03274253 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 0,01063594 0,03271492 ! Golgi lumen GO:0005796 8 8 0,000 0,01063594 0,03268736 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 0,01063594 0,03265984 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 0,01063594 0,03263237 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 0,01063594 0,03260495 ! stereocilium bundle GO:0032421 11 8 0,000 0,01063594 0,03257758 ! forebrain cell migration GO:0021885 9 8 0,000 0,01063594 0,03255025 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 0,01063594 0,03252296 ! osteoblast development GO:0002076 11 8 0,000 0,01063594 0,03249572 ! retinoic acid metabolic process GO:0042573 8 8 0,000 0,01063594 0,03246853 ! retinol metabolic process GO:0042572 8 8 0,000 0,01063594 0,03244138 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 0,01063594 0,03241428 ! structural constituent of epidermis GO:0030280 9 8 0,000 0,01063594 0,03238722 ! clathrin binding GO:0030276 10 8 0,000 0,01063594 0,03236021 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 0,01063594 0,03233324 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 0,01063594 0,03230632 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 0,01063594 0,03227945 ! motor axon guidance GO:0008045 8 8 0,000 0,01063594 0,03225261 ! protein targeting to vacuole GO:0006623 8 8 0,000 0,01063594 0,03222583 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 0,01063594 0,03219908 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 0,01063594 0,03217238 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 0,01063594 0,03214573 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01063594 0,03211912 ! protein-lipid complex assembly GO:0065005 8 8 0,000 0,01063594 0,03209255 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 0,01063594 0,03206603 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 0,01063594 0,03203955 ! regulation of dopamine secretion GO:0014059 9 8 0,000 0,01063594 0,03201311 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 0,01063594 0,03198672 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 0,01063594 0,03196037 ! subpallium development GO:0021544 8 8 0,000 0,01063594 0,03193407 ! icosanoid secretion GO:0032309 10 8 0,000 0,01063594 0,03190781 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 0,01063594 0,03188159 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 0,01063594 0,03185541 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 0,01063594 0,03182928 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 0,01063594 0,03180319 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 0,01063594 0,03177714 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 0,01063594 0,03175114 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 0,01063594 0,03172518 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 0,01063594 0,03169926 ! ubiquinone metabolic process GO:0006743 9 8 0,000 0,01063594 0,03167338 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 0,01063594 0,03164755 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 0,01063594 0,03162176 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 0,01063594 0,031596 ! Wnt receptor activity GO:0042813 11 8 0,000 0,01063594 0,0315703 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 0,01063594 0,03154463 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 0,01063594 0,031519 ! detection of calcium ion GO:0005513 9 8 0,000 0,01063594 0,03149342 ! negative regulation of glucose import GO:0046325 9 8 0,000 0,01063594 0,03146788 ! blastocyst growth GO:0001832 8 8 0,000 0,01063594 0,03144238 ! regulation of fibrinolysis GO:0051917 8 8 0,000 0,01063594 0,03141692 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 0,01063594 0,0313915 ! cerebellar cortex formation GO:0021697 9 8 0,000 0,01063594 0,03136612 ! complement binding GO:0001848 11 8 0,000 0,01063594 0,03134079 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 0,01063594 0,03131549 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 0,01063594 0,03129024 ! amino sugar catabolic process GO:0046348 8 8 0,000 0,01063594 0,03126502 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 0,01063594 0,03123985 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 0,01063594 0,03121472 ! positive regulation of amine transport GO:0051954 9 8 0,000 0,01063594 0,03118963 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 0,01063594 0,03116457 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 0,01063594 0,03113956 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01063594 0,03111459 ! Golgi transport complex GO:0017119 8 8 0,000 0,01063594 0,03108966 ! positive regulation of protein ubiquitination GO:0031398 17 8 0,000 0,01063594 0,03106477 ! GDP binding GO:0019003 9 8 0,000 0,01063594 0,03103992 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 0,01063594 0,0310151 ! prostate gland development GO:0030850 17 8 0,000 0,01063594 0,03099033 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 0,01063594 0,0309656 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 0,01063594 0,0309409 ! phosphate transport GO:0006817 9 8 0,000 0,01063594 0,03091625 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 0,01063594 0,03089164 ! oligopeptide transport GO:0006857 8 8 0,000 0,01063594 0,03086706 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 0,01063594 0,03084252 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 0,01063594 0,03081803 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 0,01063594 0,03079357 ! lipoprotein transport GO:0042953 9 8 0,000 0,01063594 0,03076915 ! estrogen metabolic process GO:0008210 8 8 0,000 0,01063594 0,03074477 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 0,01063594 0,03072042 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 0,01063594 0,03069612 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 0,01063594 0,03067185 ! T-helper 1 type immune response GO:0042088 8 8 0,000 0,01063594 0,03064763 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 0,01063594 0,03062344 ! response to amphetamine GO:0001975 11 8 0,000 0,01063594 0,03059929 ! mechanosensory behavior GO:0007638 8 8 0,000 0,01063594 0,03057517 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 0,01063594 0,0305511 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 0,01063594 0,03052706 ! C-X-C chemokine binding GO:0019958 8 8 0,000 0,01063594 0,03050306 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 0,01063594 0,0304791 ! glycerolipid catabolic process GO:0046503 17 8 0,000 0,01063594 0,03045518 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 0,01063594 0,03043129 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 0,01063594 0,03040744 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 0,01063594 0,03038363 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 0,01063594 0,03035985 ! pigment granule organization GO:0048753 9 8 0,000 0,01063594 0,03033612 ! GTP-dependent protein binding GO:0030742 11 8 0,000 0,01063594 0,03031242 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 0,01063594 0,03028875 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 0,01063594 0,03026513 ! regulation of pigmentation during development GO:0048070 11 8 0,000 0,01063594 0,03024154 ! macrophage activation GO:0042116 8 8 0,000 0,01063594 0,03021799 ! poly(A) RNA binding GO:0008143 8 8 0,000 0,01063594 0,03019447 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 0,01063594 0,03017099 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 0,01063594 0,03014755 ! asymmetric protein localization GO:0008105 9 8 0,000 0,01063594 0,03012414 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 0,01063594 0,03010077 ! neurotrophin binding GO:0043121 10 8 0,000 0,01063594 0,03007744 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 0,01063594 0,03005414 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 0,01063594 0,03003088 ! phagocytosis, engulfment GO:0006911 10 8 0,000 0,01063594 0,03000765 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 0,01063594 0,02998446 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 0,01063594 0,02996131 ! UV protection GO:0009650 9 8 0,000 0,01063594 0,02993819 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 0,01063594 0,02991511 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 0,01063594 0,02989206 ! glutathione peroxidase activity GO:0004602 17 8 0,000 0,01063594 0,02986905 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 0,01063594 0,02984607 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 0,01063594 0,02982313 ! ferric iron binding GO:0008199 9 8 0,000 0,01063594 0,02980023 ! response to UV-B GO:0010224 10 8 0,000 0,01063594 0,02977736 ! intermediate filament organization GO:0045109 8 8 0,000 0,01063594 0,02975452 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 0,01063594 0,02973172 ! cellular extravasation GO:0045123 9 8 0,000 0,01063594 0,02970895 ! skeletal muscle contraction GO:0003009 8 8 0,000 0,01063594 0,02968622 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 0,01063594 0,02966353 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 0,000 0,01063594 0,02964087 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01063594 0,02961824 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 0,01063594 0,02959565 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 0,01063594 0,02957309 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 0,01063594 0,02955057 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 0,01063594 0,02952808 ! erythrocyte development GO:0048821 9 8 0,000 0,01063594 0,02950562 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 0,01063594 0,0294832 ! ribosome assembly GO:0042255 8 8 0,000 0,01063594 0,02946082 ! postreplication repair GO:0006301 19 8 0,000 0,01063594 0,02943846 ! gamma-tubulin binding GO:0043015 8 8 0,000 0,01063594 0,02941614 ! NADPH oxidase complex GO:0043020 8 8 0,000 0,01063594 0,02939386 ! mRNA cleavage GO:0006379 9 8 0,000 0,01063594 0,02937161 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 0,01063594 0,02934939 ! opioid receptor activity GO:0004985 8 8 0,000 0,01063594 0,02932721 ! zymogen activation GO:0031638 9 8 0,000 0,01063594 0,02930506 ! coenzyme A metabolic process GO:0015936 8 8 0,000 0,01063594 0,02928294 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 0,01063594 0,02926086 ! costamere GO:0043034 8 8 0,000 0,01063594 0,0292388 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 0,01063594 0,02921679 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 0,01063594 0,0291948 ! sarcomere organization GO:0045214 9 8 0,000 0,01063594 0,02917285 ! wide pore channel activity GO:0022829 9 8 0,000 0,01063594 0,02915093 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 0,01063594 0,02912905 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 0,01063594 0,0291072 ! hormone catabolic process GO:0042447 9 8 0,000 0,01063594 0,02908538 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 0,01063594 0,02906359 ! cGMP biosynthetic process GO:0006182 9 8 0,000 0,01063594 0,02904184 ! lysozyme activity GO:0003796 10 8 0,000 0,01063594 0,02902012 ! death receptor binding GO:0005123 8 8 0,000 0,01063594 0,02899843 ! protein modification by small protein removal GO:0070646 9 8 0,000 0,01063594 0,02897677 ! adult feeding behavior GO:0008343 9 8 0,000 0,01063594 0,02895514 ! microtubule basal body GO:0005932 8 8 0,000 0,01063594 0,02893355 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 0,01063594 0,02891199 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 0,01063594 0,02889046 ! calcium-release channel activity GO:0015278 8 8 0,000 0,01063594 0,02886897 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 0,01063594 0,0288475 ! behavioral response to nicotine GO:0035095 9 8 0,000 0,01063594 0,02882607 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 0,01063594 0,02880467 ! adenosine deaminase activity GO:0004000 8 8 0,000 0,01063594 0,0287833 ! NAD biosynthetic process GO:0009435 9 8 0,000 0,01063594 0,02876197 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 0,01195777 0,03231254 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 0,01195777 0,03228863 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 0,01195777 0,03226474 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 0,01195777 0,0322409 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 0,01195777 0,03221709 ! myotube differentiation GO:0014902 9 9 0,000 0,01195777 0,03219331 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 0,01195777 0,03216957 ! N-glycan processing GO:0006491 10 9 0,000 0,01195777 0,03214586 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 0,01195777 0,03212219 ! actin-myosin filament sliding GO:0033275 11 9 0,000 0,01195777 0,03209855 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 0,01195777 0,03207495 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 0,01195777 0,03205138 ! RNA methylation GO:0001510 9 9 0,000 0,01195777 0,03202785 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 0,01195777 0,03200435 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 0,01195777 0,03198089 ! artery development GO:0060840 9 9 0,000 0,01195777 0,03195746 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 0,01195777 0,03193407 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 0,01195777 0,0319107 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 0,01195777 0,03188738 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 0,01195777 0,03186409 ! positive regulation of heart contraction GO:0045823 11 9 0,000 0,01195777 0,03184083 ! lipopolysaccharide binding GO:0001530 9 9 0,000 0,01195777 0,0318176 ! regulated secretory pathway GO:0045055 10 9 0,000 0,01195777 0,03179441 ! estrogen receptor binding GO:0030331 9 9 0,000 0,01195777 0,03177126 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 0,01195777 0,03174813 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 0,01195777 0,03172504 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 0,01195777 0,03170199 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 0,01195777 0,03167896 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! urea metabolic process GO:0019627 19 9 0,000 0,01195777 0,03165597 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 0,01195777 0,03163302 ! autophagic vacuole GO:0005776 11 9 0,000 0,01195777 0,0316101 ! Rac GTPase binding GO:0048365 10 9 0,000 0,01195777 0,03158721 ! response to dietary excess GO:0002021 9 9 0,000 0,01195777 0,03156435 ! regulation of sodium ion transport GO:0002028 10 9 0,000 0,01195777 0,03154153 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01195777 0,03151874 ! lens development in camera-type eye GO:0002088 9 9 0,000 0,01195777 0,03149598 ! male sex determination GO:0030238 9 9 0,000 0,01195777 0,03147326 ! positive regulation of vasodilation GO:0045909 19 9 0,000 0,01195777 0,03145056 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 0,01195777 0,03142791 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 0,01195777 0,03140528 ! male germ cell nucleus GO:0001673 11 9 0,000 0,01195777 0,03138269 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 0,01195777 0,03136012 ! copper ion homeostasis GO:0055070 9 9 0,000 0,01195777 0,0313376 ! protein heterooligomerization GO:0051291 10 9 0,000 0,01195777 0,0313151 ! spectrin GO:0008091 9 9 0,000 0,01195777 0,03129264 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 0,01195777 0,0312702 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 0,01195777 0,0312478 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 0,01195777 0,03122544 ! regulation of B cell differentiation GO:0045577 10 9 0,000 0,01195777 0,0312031 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 0,01195777 0,0311808 ! neural tube patterning GO:0021532 10 9 0,000 0,01195777 0,03115852 ! fucose catabolic process GO:0019317 10 9 0,000 0,01195777 0,03113628 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 0,01195777 0,03111408 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 0,01195777 0,0310919 ! sterol catabolic process GO:0016127 10 9 0,000 0,01195777 0,03106975 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 0,01195777 0,03104764 ! clathrin coat of coated pit GO:0030132 11 9 0,000 0,01195777 0,03102556 ! SNARE complex GO:0031201 11 9 0,000 0,01195777 0,03100351 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 0,01195777 0,03098149 ! negative regulation of glucose transport GO:0010829 10 9 0,000 0,01195777 0,0309595 ! methionine biosynthetic process GO:0009086 11 9 0,000 0,01195777 0,03093754 ! peptidoglycan binding GO:0042834 9 9 0,000 0,01195777 0,03091562 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 0,01195777 0,03089372 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 0,01195777 0,03087186 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 0,01195777 0,03085002 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 0,01195777 0,03082822 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 0,01195777 0,03080645 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 0,01195777 0,03078471 ! detection of bacterium GO:0016045 10 9 0,000 0,01195777 0,030763 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 0,01195777 0,03074132 ! embryonic gut development GO:0048566 10 9 0,000 0,01195777 0,03071967 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 0,01195777 0,03069805 ! desmosome GO:0030057 10 9 0,000 0,01195777 0,03067647 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 0,01195777 0,03065491 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 0,01195777 0,03063338 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 0,01195777 0,03061188 ! actin filament polymerization GO:0030041 10 9 0,000 0,01195777 0,03059042 ! negative regulation of B cell activation GO:0050869 10 9 0,000 0,01195777 0,03056898 ! establishment of cell polarity GO:0030010 10 9 0,000 0,01195777 0,03054757 ! regulation of synapse organization GO:0050807 10 9 0,000 0,01195777 0,0305262 ! septin complex GO:0031105 10 9 0,000 0,01195777 0,03050485 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 0,01195777 0,03048353 ! anchoring collagen GO:0030934 9 9 0,000 0,01195777 0,03046224 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 0,01195777 0,03044099 ! regulation of developmental growth GO:0048638 11 9 0,000 0,01195777 0,03041976 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 0,01195777 0,03039856 ! GMP binding GO:0019002 11 9 0,000 0,01195777 0,03037739 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 0,01195777 0,03035625 ! virus-host interaction GO:0019048 13 9 0,000 0,01195777 0,03033514 ! pentose-phosphate shunt GO:0006098 11 9 0,000 0,01195777 0,03031406 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 0,01195777 0,03029301 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 0,01195777 0,03027199 ! non-recombinational repair GO:0000726 10 9 0,000 0,01195777 0,03025099 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 0,01195777 0,03023003 ! nuclear telomere cap complex GO:0000783 10 9 0,000 0,01195777 0,0302091 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 0,01195777 0,03018819 ! social behavior GO:0035176 10 9 0,000 0,01195777 0,03016731 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 0,01195777 0,03014646 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 0,01195777 0,03012564 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 0,01195777 0,03010485 ! mating GO:0007618 11 9 0,000 0,01195777 0,03008409 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 0,01195777 0,03006336 ! rhythmic behavior GO:0007622 11 9 0,000 0,01195777 0,03004265 ! phospholipid efflux GO:0033700 10 9 0,000 0,01195777 0,03002198 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 0,01195777 0,03000133 ! poly-purine tract binding GO:0070717 9 9 0,000 0,01195777 0,02998071 ! T cell proliferation GO:0042098 10 9 0,000 0,01195777 0,02996012 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 0,01195777 0,02993956 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 0,01195777 0,02991902 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 0,01195777 0,02989851 ! interleukin-1 binding GO:0019966 10 9 0,000 0,01195777 0,02987804 ! glucosyltransferase activity GO:0046527 9 9 0,000 0,01195777 0,02985759 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 0,01195777 0,02983716 ! ovulation GO:0030728 9 9 0,000 0,01195777 0,02981677 ! acid phosphatase activity GO:0003993 18 9 0,000 0,01195777 0,0297964 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 0,01195777 0,02977606 ! ER overload response GO:0006983 11 9 0,000 0,01195777 0,02975575 ! B cell proliferation GO:0042100 10 9 0,000 0,01195777 0,02973547 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 0,01195777 0,02971521 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 0,01195777 0,02969499 ! mannose metabolic process GO:0006013 13 9 0,000 0,01195777 0,02967478 ! lipid digestion GO:0044241 11 9 0,000 0,01195777 0,02965461 ! tumor necrosis factor binding GO:0043120 9 9 0,000 0,01195777 0,02963447 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 0,01195777 0,02961435 ! regulation of bone resorption GO:0045124 10 9 0,000 0,01195777 0,02959426 ! brain morphogenesis GO:0048854 9 9 0,000 0,01195777 0,02957419 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 0,01195777 0,02955416 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 0,01195777 0,02953415 ! synaptic vesicle membrane GO:0030672 9 9 0,000 0,01195777 0,02951416 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 0,01195777 0,02949421 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 0,01195777 0,02947428 ! kinesin binding GO:0019894 9 9 0,000 0,01195777 0,02945438 ! multicellular organismal aging GO:0010259 18 9 0,000 0,01195777 0,0294345 ! Ran GTPase binding GO:0008536 11 9 0,000 0,01195777 0,02941465 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 0,01195777 0,02939483 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 0,01195777 0,02937504 ! mRNA polyadenylation GO:0006378 10 9 0,000 0,01195777 0,02935527 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 0,01195777 0,02933553 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 0,01195777 0,02931582 ! prostaglandin receptor activity GO:0004955 11 9 0,000 0,01195777 0,02929613 ! caspase inhibitor activity GO:0043027 9 9 0,000 0,01195777 0,02927647 ! adrenoceptor activity GO:0004935 12 9 0,000 0,01195777 0,02925683 ! regulation of isotype switching GO:0045191 9 9 0,000 0,01195777 0,02923722 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 0,01195777 0,02921764 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 0,01195777 0,02919808 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 0,01195777 0,02917855 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 0,01195777 0,02915905 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 0,01195777 0,02913957 ! Notch binding GO:0005112 10 9 0,000 0,01195777 0,02912012 ! ATPase regulator activity GO:0060590 10 9 0,000 0,01195777 0,02910069 ! gamma-tubulin complex GO:0000930 19 9 0,000 0,01195777 0,02908129 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 0,01195777 0,02906191 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 0,01195777 0,02904257 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 0,01195777 0,02902324 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 0,01195777 0,02900395 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 0,000 0,0132779 0,03218458 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,0132779 0,03216321 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,0132779 0,03214186 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,0132779 0,03212055 ! sleep GO:0030431 11 10 0,000 0,0132779 0,03209926 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,0132779 0,03207801 ! lipid particle GO:0005811 10 10 0,000 0,0132779 0,03205678 ! filopodium assembly GO:0046847 14 10 0,000 0,0132779 0,03203557 ! UTP metabolic process GO:0046051 12 10 0,000 0,0132779 0,0320144 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,0132779 0,03199325 ! guanylate kinase activity GO:0004385 14 10 0,000 0,0132779 0,03197214 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,0132779 0,03195105 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,0132779 0,03192999 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,0132779 0,03190895 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,0132779 0,03188794 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,0132779 0,03186697 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,0132779 0,03184601 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,0132779 0,03182509 ! lung alveolus development GO:0048286 11 10 0,000 0,0132779 0,03180419 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,0132779 0,03178333 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0132779 0,03176248 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,0132779 0,03174167 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,0132779 0,03172088 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,0132779 0,03170012 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,0132779 0,03167939 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,0132779 0,03165868 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,0132779 0,03163801 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,0132779 0,03161735 ! histidine metabolic process GO:0006547 10 10 0,000 0,0132779 0,03159673 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,0132779 0,03157613 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,0132779 0,03155556 ! death receptor activity GO:0005035 11 10 0,000 0,0132779 0,03153502 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,0132779 0,0315145 ! entry into host cell GO:0030260 11 10 0,000 0,0132779 0,03149401 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,0132779 0,03147355 ! filamentous actin GO:0031941 11 10 0,000 0,0132779 0,03145311 ! behavioral fear response GO:0001662 12 10 0,000 0,0132779 0,0314327 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,0132779 0,03141231 ! negative regulation of ossification GO:0030279 12 10 0,000 0,0132779 0,03139196 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,0132779 0,03137162 ! macrophage differentiation GO:0030225 11 10 0,000 0,0132779 0,03135132 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,0132779 0,03133104 ! recycling endosome membrane GO:0055038 11 10 0,000 0,0132779 0,03131079 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,0132779 0,03129056 ! snRNA metabolic process GO:0016073 10 10 0,000 0,0132779 0,03127036 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,0132779 0,03125019 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 0,0132779 0,03123004 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,0132779 0,03120991 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,0132779 0,03118982 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,0132779 0,03116975 ! induction of an organ GO:0001759 12 10 0,000 0,0132779 0,0311497 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,0132779 0,03112968 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,0132779 0,03110969 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,0132779 0,03108972 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,0132779 0,03106978 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,0132779 0,03104986 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,0132779 0,03102997 ! ribonuclease P activity GO:0004526 10 10 0,000 0,0132779 0,03101011 ! COPI vesicle coat GO:0030126 12 10 0,000 0,0132779 0,03099027 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,0132779 0,03097045 ! vitamin transporter activity GO:0051183 12 10 0,000 0,0132779 0,03095066 ! snRNA binding GO:0017069 11 10 0,000 0,0132779 0,0309309 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,0132779 0,03091116 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,0132779 0,03089145 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,0132779 0,03087176 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,0132779 0,03085209 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,0132779 0,03083246 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,0132779 0,03081284 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,0132779 0,03079325 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,0132779 0,03077369 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,0132779 0,03075415 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,0132779 0,03073464 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 0,0132779 0,03071515 ! extracellular matrix binding GO:0050840 11 10 0,000 0,0132779 0,03069568 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,0132779 0,03067624 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,0132779 0,03065683 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,0132779 0,03063744 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,0132779 0,03061807 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 0,0132779 0,03059873 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,0132779 0,03057941 ! thyroid gland development GO:0030878 12 10 0,000 0,0132779 0,03056012 ! DNA bending activity GO:0008301 11 10 0,000 0,0132779 0,03054085 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,0132779 0,03052161 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,0132779 0,03050239 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,0132779 0,03048319 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,0132779 0,03046402 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,0132779 0,03044487 ! regulation of glycolysis GO:0006110 11 10 0,000 0,0132779 0,03042575 ! nucleotidase activity GO:0008252 10 10 0,000 0,0132779 0,03040665 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,0132779 0,03038757 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,0132779 0,03036852 ! androgen metabolic process GO:0008209 11 10 0,000 0,0132779 0,03034949 ! lateral plasma membrane GO:0016328 13 10 0,000 0,0132779 0,03033049 ! MAP kinase kinase activity GO:0004708 12 10 0,000 0,0132779 0,03031151 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,0132779 0,03029255 ! startle response GO:0001964 13 10 0,000 0,0132779 0,03027362 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,0132779 0,03025471 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,0132779 0,03023582 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,0132779 0,03021696 ! spinal cord patterning GO:0021511 12 10 0,000 0,0132779 0,03019812 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,0132779 0,03017931 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,0132779 0,03016052 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,0132779 0,03014175 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,0132779 0,030123 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,0132779 0,03010428 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,0132779 0,03008558 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,0132779 0,03006691 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,0132779 0,03004826 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,0132779 0,03002963 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,0132779 0,03001102 ! adult heart development GO:0007512 14 10 0,000 0,0132779 0,02999244 ! neuromuscular junction development GO:0007528 12 10 0,000 0,0132779 0,02997388 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,0132779 0,02995534 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,0132779 0,02993683 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,0132779 0,02991834 ! signalosome GO:0008180 10 10 0,000 0,0132779 0,02989987 ! lysophospholipase activity GO:0004622 19 10 0,000 0,0132779 0,02988142 ! prefoldin complex GO:0016272 10 10 0,000 0,0132779 0,029863 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,0132779 0,0298446 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,0132779 0,02982622 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,0132779 0,02980787 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,0132779 0,02978954 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,0132779 0,02977123 ! gland morphogenesis GO:0022612 11 10 0,000 0,0132779 0,02975294 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,0132779 0,02973468 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,0132779 0,02971643 ! peptide transporter activity GO:0015197 10 10 0,000 0,0132779 0,02969821 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,0132779 0,02968002 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,0132779 0,02966184 ! muscle maintenance GO:0046716 10 10 0,000 0,0132779 0,02964369 ! acid secretion GO:0046717 12 10 0,000 0,0132779 0,02962556 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,0132779 0,02960745 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,0132779 0,02958936 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,0132779 0,0295713 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,0132779 0,02955326 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,0132779 0,02953524 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,0132779 0,02951724 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,0132779 0,02949926 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,0132779 0,02948131 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,0132779 0,02946337 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,0132779 0,02944546 ! water channel activity GO:0015250 15 10 0,000 0,0132779 0,02942757 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,0132779 0,02940971 ! regulation of embryonic development GO:0045995 12 10 0,000 0,0132779 0,02939186 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 0,000 0,0132779 0,02937404 ! acrosome reaction GO:0007340 12 10 0,000 0,0132779 0,02935623 ! mitochondrion localization GO:0051646 10 10 0,000 0,0132779 0,02933845 ! cilium part GO:0044441 10 10 0,000 0,0132779 0,02932069 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,01459634 0,03221262 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,01459634 0,03219315 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,01459634 0,03217369 ! centriole GO:0005814 11 11 0,000 0,01459634 0,03215427 ! cadmium ion binding GO:0046870 15 11 0,000 0,01459634 0,03213486 ! hemoglobin complex GO:0005833 13 11 0,000 0,01459634 0,03211548 ! CTP metabolic process GO:0046036 13 11 0,000 0,01459634 0,03209612 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,01459634 0,03207679 ! response to pain GO:0048265 12 11 0,000 0,01459634 0,03205747 ! regulation of viral genome replication GO:0045069 13 11 0,000 0,01459634 0,03203819 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,01459634 0,03201892 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,01459634 0,03199968 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,01459634 0,03198046 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,01459634 0,03196126 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01459634 0,03194209 ! peptide antigen binding GO:0042605 14 11 0,000 0,01459634 0,03192294 ! polyamine metabolic process GO:0006595 11 11 0,000 0,01459634 0,03190381 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,01459634 0,03188471 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,01459634 0,03186563 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,01459634 0,03184657 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,01459634 0,03182753 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,01459634 0,03180852 ! protein homotetramerization GO:0051289 13 11 0,000 0,01459634 0,03178953 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,01459634 0,03177056 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,01459634 0,03175162 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,01459634 0,0317327 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,01459634 0,0317138 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,01459634 0,03169492 ! response to dsRNA GO:0043331 21 11 0,000 0,01459634 0,03167606 ! response to amine stimulus GO:0014075 15 11 0,000 0,01459634 0,03165723 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,01459634 0,03163842 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,01459634 0,03161963 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,01459634 0,03160087 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,01459634 0,03158213 ! retinal binding GO:0016918 11 11 0,000 0,01459634 0,03156341 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,01459634 0,03154471 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,01459634 0,03152603 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,01459634 0,03150738 ! autonomic nervous system development GO:0048483 12 11 0,000 0,01459634 0,03148874 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,01459634 0,03147013 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,01459634 0,03145154 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,01459634 0,03143298 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,01459634 0,03141443 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,01459634 0,03139591 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,01459634 0,03137741 ! regulation of epidermis development GO:0045682 14 11 0,000 0,01459634 0,03135893 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,01459634 0,03134047 ! midbrain development GO:0030901 12 11 0,000 0,01459634 0,03132204 ! musculoskeletal movement GO:0050881 12 11 0,000 0,01459634 0,03130362 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 0,01459634 0,03128523 ! regulation of RNA stability GO:0043487 13 11 0,000 0,01459634 0,03126686 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,01459634 0,03124851 ! cell killing GO:0001906 13 11 0,000 0,01459634 0,03123018 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,01459634 0,03121188 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,01459634 0,03119359 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,01459634 0,03117533 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 0,01459634 0,03115709 ! folic acid binding GO:0005542 12 11 0,000 0,01459634 0,03113887 ! mRNA 3'-end processing GO:0031124 12 11 0,000 0,01459634 0,03112067 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,01459634 0,03110249 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,01459634 0,03108433 ! microspike assembly GO:0030035 15 11 0,000 0,01459634 0,0310662 ! lamellipodium assembly GO:0030032 22 11 0,000 0,01459634 0,03104808 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,01459634 0,03102999 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,01459634 0,03101192 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,01459634 0,03099387 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,01459634 0,03097584 ! synaptonemal complex GO:0000795 11 11 0,000 0,01459634 0,03095783 ! reproductive cellular process GO:0048610 13 11 0,000 0,01459634 0,03093984 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,01459634 0,03092187 ! positive regulation of B cell proliferation GO:0030890 15 11 0,000 0,01459634 0,03090393 ! Golgi vesicle budding GO:0048194 12 11 0,000 0,01459634 0,030886 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,01459634 0,0308681 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,01459634 0,03085021 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01459634 0,03083235 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,01459634 0,03081451 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,01459634 0,03079668 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,01459634 0,03077888 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 0,01459634 0,0307611 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,01459634 0,03074334 ! drug transport GO:0015893 12 11 0,000 0,01459634 0,0307256 ! FMN binding GO:0010181 12 11 0,000 0,01459634 0,03070788 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,01459634 0,03069018 ! water transporter activity GO:0005372 17 11 0,000 0,01459634 0,0306725 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,01459634 0,03065484 GO:0032881|regulation of polysaccharide metabolic process, ! multicellular organism growth GO:0035264 12 11 0,000 0,01459634 0,03063721 ! integrator complex GO:0032039 11 11 0,000 0,01459634 0,03061959 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,01459634 0,03060199 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,01459634 0,03058441 ! brush border membrane GO:0031526 12 11 0,000 0,01459634 0,03056686 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,01459634 0,03054932 ! macroautophagy GO:0016236 12 11 0,000 0,01459634 0,0305318 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,01459634 0,03051431 ! neuromuscular junction GO:0031594 12 11 0,000 0,01459634 0,03049683 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,01459634 0,03047937 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 0,01459634 0,03046194 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,01459634 0,03044452 ! response to antibiotic GO:0046677 13 11 0,000 0,01459634 0,03042712 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,01459634 0,03040975 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,01459634 0,03039239 ! proteasome accessory complex GO:0022624 11 11 0,000 0,01459634 0,03037505 ! neuroblast proliferation GO:0007405 13 11 0,000 0,01459634 0,03035773 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,01459634 0,03034044 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,01459634 0,03032316 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,01459634 0,0303059 ! protein kinase C binding GO:0005080 11 11 0,000 0,01459634 0,03028866 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,01459634 0,03027144 ! male genitalia development GO:0030539 15 11 0,000 0,01459634 0,03025424 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,01459634 0,03023706 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,01459634 0,0302199 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,01459634 0,03020276 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,01459634 0,03018564 ! arylsulfatase activity GO:0004065 12 11 0,000 0,01459634 0,03016854 ! sterol transporter activity GO:0015248 11 11 0,000 0,01459634 0,03015145 ! response to nicotine GO:0035094 13 11 0,000 0,01459634 0,03013439 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01459634 0,03011734 ! rRNA transcription GO:0009303 12 12 0,000 0,0159131 0,0328157 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,0159131 0,03279716 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,0159131 0,03277864 ! superoxide anion generation GO:0042554 12 12 0,000 0,0159131 0,03276014 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,0159131 0,03274166 ! regulation of S phase GO:0033261 16 12 0,000 0,0159131 0,03272321 ! regulation of chemokine production GO:0032642 13 12 0,000 0,0159131 0,03270477 ! male meiosis GO:0007140 12 12 0,000 0,0159131 0,03268636 ! signal complex assembly GO:0007172 15 12 0,000 0,0159131 0,03266796 ! GTP metabolic process GO:0046039 14 12 0,000 0,0159131 0,03264959 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,0159131 0,03263124 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,0159131 0,03261291 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,0159131 0,03259459 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,0159131 0,0325763 ! cartilage condensation GO:0001502 14 12 0,000 0,0159131 0,03255803 ! polysome GO:0005844 14 12 0,000 0,0159131 0,03253978 ! hippocampus development GO:0021766 13 12 0,000 0,0159131 0,03252155 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,0159131 0,03250334 ! beta-amyloid binding GO:0001540 12 12 0,000 0,0159131 0,03248515 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,0159131 0,03246699 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,0159131 0,03244884 ! regulation of exit from mitosis GO:0007096 31 12 0,000 0,0159131 0,03243071 ! chylomicron GO:0042627 13 12 0,000 0,0159131 0,0324126 ! T cell selection GO:0045058 22 12 0,000 0,0159131 0,03239452 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,0159131 0,03237645 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,0159131 0,0323584 ! WW domain binding GO:0050699 12 12 0,000 0,0159131 0,03234037 ! methionine metabolic process GO:0006555 14 12 0,000 0,0159131 0,03232237 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,0159131 0,03230438 ! glycine metabolic process GO:0006544 14 12 0,000 0,0159131 0,03228641 ! plasma membrane organization GO:0007009 12 12 0,000 0,0159131 0,03226847 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,0159131 0,03225054 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,0159131 0,03223263 ! Golgi organization GO:0007030 15 12 0,000 0,0159131 0,03221475 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,0159131 0,03219688 ! mitotic spindle organization GO:0007052 13 12 0,000 0,0159131 0,03217903 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,0159131 0,0321612 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,0159131 0,0321434 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,0159131 0,03212561 ! temperature homeostasis GO:0001659 13 12 0,000 0,0159131 0,03210784 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,0159131 0,03209009 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,0159131 0,03207236 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,0159131 0,03205465 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,0159131 0,03203696 ! axon cargo transport GO:0008088 13 12 0,000 0,0159131 0,03201929 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,0159131 0,03200164 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,0159131 0,03198401 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,0159131 0,03196639 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,0159131 0,0319488 ! basal lamina GO:0005605 12 12 0,000 0,0159131 0,03193123 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,0159131 0,03191367 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,0159131 0,03189614 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,0159131 0,03187862 ! water homeostasis GO:0030104 12 12 0,000 0,0159131 0,03186113 ! promoter binding GO:0010843 14 12 0,000 0,0159131 0,03184365 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,0159131 0,03182619 ! intestinal absorption GO:0050892 14 12 0,000 0,0159131 0,03180875 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,0159131 0,03179133 ! oocyte differentiation GO:0009994 13 12 0,000 0,0159131 0,03177393 ! oxygen transport GO:0015671 13 12 0,000 0,0159131 0,03175655 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,0159131 0,03173919 ! cholesterol efflux GO:0033344 13 12 0,000 0,0159131 0,03172184 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,0159131 0,03170452 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,0159131 0,03168721 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,0159131 0,03166992 ! tropomyosin binding GO:0005523 12 12 0,000 0,0159131 0,03165266 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,0159131 0,03163541 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,0159131 0,03161818 ! mannose binding GO:0005537 13 12 0,000 0,0159131 0,03160096 ! phosphoprotein binding GO:0051219 14 12 0,000 0,0159131 0,03158377 ! defense response to fungus GO:0050832 12 12 0,000 0,0159131 0,0315666 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,0159131 0,03154944 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,0159131 0,0315323 ! acyl-CoA binding GO:0000062 12 12 0,000 0,0159131 0,03151519 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,0159131 0,03149809 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,0159131 0,031481 ! copper ion transport GO:0006825 12 12 0,000 0,0159131 0,03146394 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,0159131 0,0314469 ! inositol metabolic process GO:0006020 21 12 0,000 0,0159131 0,03142987 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,0159131 0,03141286 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,0159131 0,03139587 ! protein complex disassembly GO:0043241 15 12 0,000 0,0159131 0,0313789 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,0159131 0,03136195 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,0159131 0,03134502 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,0159131 0,0313281 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,0159131 0,0313112 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,0159131 0,03129432 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,0159131 0,03127746 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,0159131 0,03126062 ! endoderm development GO:0007492 13 12 0,000 0,0159131 0,0312438 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,0159131 0,03122699 ! focal adhesion formation GO:0048041 16 12 0,000 0,0159131 0,0312102 ! T cell receptor complex GO:0042101 31 12 0,000 0,0159131 0,03119343 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,0159131 0,03117668 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,0159131 0,03115994 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,0159131 0,03114323 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,0159131 0,03112653 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,0159131 0,03110985 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,0159131 0,03109318 ! retinol binding GO:0019841 12 12 0,000 0,0159131 0,03107654 ! regulation of organ growth GO:0046620 12 12 0,000 0,0159131 0,03105991 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,0159131 0,0310433 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,0159131 0,03102671 ! histone acetylation GO:0016573 13 12 0,000 0,0159131 0,03101013 ! ribosome binding GO:0043022 13 12 0,000 0,0159131 0,03099358 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,0159131 0,03097704 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,0159131 0,03096052 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,0159131 0,03094401 ! tissue regeneration GO:0042246 12 12 0,000 0,0159131 0,03092753 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,0159131 0,03091106 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,0159131 0,03089461 ! germ cell nucleus GO:0043073 14 12 0,000 0,0159131 0,03087818 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,0159131 0,03086176 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,0159131 0,03084536 ! hexosaminidase activity GO:0015929 12 12 0,000 0,0159131 0,03082898 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,0159131 0,03081262 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,0159131 0,03079627 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,0159131 0,03077994 ! dopamine metabolic process GO:0042417 15 12 0,000 0,0159131 0,03076363 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,0159131 0,03074734 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,0159131 0,03073106 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,0159131 0,0307148 ! bacterial binding GO:0008367 14 12 0,000 0,0159131 0,03069856 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,0159131 0,03068233 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,0159131 0,03066612 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,0159131 0,03064993 ! localization within membrane GO:0051668 13 12 0,000 0,0159131 0,03063376 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,0159131 0,0306176 ! axoneme part GO:0044447 12 12 0,000 0,0159131 0,03060146 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01722816 0,03311292 ! neuron maturation GO:0042551 14 13 0,000 0,01722816 0,03309548 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01722816 0,03307806 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01722816 0,03306066 ! bone remodeling GO:0046849 14 13 0,000 0,01722816 0,03304328 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01722816 0,03302592 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01722816 0,03300857 ! striated muscle thin filament GO:0005865 14 13 0,000 0,01722816 0,03299124 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01722816 0,03297393 ! organelle fusion GO:0048284 16 13 0,000 0,01722816 0,03295664 ! palate development GO:0060021 15 13 0,000 0,01722816 0,03293937 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01722816 0,03292211 ! arginine metabolic process GO:0006525 14 13 0,000 0,01722816 0,03290488 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01722816 0,03288766 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01722816 0,03287046 ! response to retinoic acid GO:0032526 17 13 0,000 0,01722816 0,03285328 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01722816 0,03283611 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01722816 0,03281896 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01722816 0,03280184 ! fear response GO:0042596 15 13 0,000 0,01722816 0,03278472 ! epithelial cell development GO:0002064 22 13 0,000 0,01722816 0,03276763 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,01722816 0,03275056 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01722816 0,0327335 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01722816 0,03271646 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01722816 0,03269944 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01722816 0,03268243 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01722816 0,03266545 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,01722816 0,03264848 ! cranial nerve development GO:0021545 15 13 0,000 0,01722816 0,03263152 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,01722816 0,03261459 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01722816 0,03259767 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,01722816 0,03258078 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01722816 0,03256389 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01722816 0,03254703 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01722816 0,03253018 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01722816 0,03251336 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01722816 0,03249654 ! NADP metabolic process GO:0006739 15 13 0,000 0,01722816 0,03247975 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01722816 0,03246297 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01722816 0,03244621 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01722816 0,03242947 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01722816 0,03241275 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01722816 0,03239604 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01722816 0,03237935 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01722816 0,03236268 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01722816 0,03234602 ! ADP binding GO:0043531 15 13 0,000 0,01722816 0,03232938 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01722816 0,03231276 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01722816 0,03229615 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01722816 0,03227957 ! neuron fate specification GO:0048665 25 13 0,000 0,01722816 0,032263 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01722816 0,03224644 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01722816 0,03222991 ! water transport GO:0006833 18 13 0,000 0,01722816 0,03221339 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01722816 0,03219688 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01722816 0,0321804 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01722816 0,03216393 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01722816 0,03214748 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01722816 0,03213104 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,01722816 0,03211462 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01722816 0,03209822 ! myoblast differentiation GO:0045445 15 13 0,000 0,01722816 0,03208184 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01722816 0,03206547 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01722816 0,03204912 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01722816 0,03203278 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01722816 0,03201646 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,01722816 0,03200016 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01722816 0,03198388 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01722816 0,03196761 ! exocrine system development GO:0035272 14 13 0,000 0,01722816 0,03195136 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01722816 0,03193512 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01722816 0,0319189 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01722816 0,0319027 ! L-glutamate transport GO:0015813 14 13 0,000 0,01722816 0,03188651 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01722816 0,03187034 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01722816 0,03185419 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01722816 0,03183805 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01722816 0,03182193 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01722816 0,03180583 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,01722816 0,03178974 ! genitalia development GO:0048806 18 13 0,000 0,01722816 0,03177367 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01722816 0,03175761 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01722816 0,03174157 ! MHC class I protein binding GO:0042288 23 13 0,000 0,01722816 0,03172555 ! histone deacetylation GO:0016575 14 13 0,000 0,01722816 0,03170954 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01722816 0,03169355 ! DNA methylation GO:0006306 15 13 0,000 0,01722816 0,03167758 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01722816 0,03166162 ! chromatin silencing GO:0006342 13 13 0,000 0,01722816 0,03164568 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01722816 0,03162975 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01722816 0,03161384 ! T cell homeostasis GO:0043029 14 13 0,000 0,01722816 0,03159795 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01722816 0,03158207 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01722816 0,03156621 ! response to gamma radiation GO:0010332 14 13 0,000 0,01722816 0,03155036 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01722816 0,03153453 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01722816 0,03151871 ! purine base metabolic process GO:0006144 15 13 0,000 0,01722816 0,03150292 ! cAMP binding GO:0030552 15 13 0,000 0,01722816 0,03148713 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01722816 0,03147137 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01722816 0,03145561 ! regulation of axon extension GO:0030516 16 13 0,000 0,01722816 0,03143988 ! drug transporter activity GO:0015238 14 13 0,000 0,01722816 0,03142416 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01722816 0,03140845 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01722816 0,03139277 ! response to cold GO:0009409 13 13 0,000 0,01722816 0,03137709 ! cadherin binding GO:0045296 16 13 0,000 0,01722816 0,03136144 ! nucleolar part GO:0044452 13 13 0,000 0,01722816 0,03134579 ! tRNA modification GO:0006400 14 14 0,000 0,01854153 0,0337186 ! cis-Golgi network GO:0005801 16 14 0,000 0,01854153 0,0337018 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,01854153 0,03368501 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,01854153 0,03366825 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,01854153 0,0336515 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,01854153 0,03363476 ! peroxisomal transport GO:0043574 14 14 0,000 0,01854153 0,03361804 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,01854153 0,03360134 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,01854153 0,03358466 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,01854153 0,03356799 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,01854153 0,03355134 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,01854153 0,03353471 ! caspase activator activity GO:0008656 16 14 0,000 0,01854153 0,03351809 ! MHC class II protein complex GO:0042613 19 14 0,000 0,01854153 0,03350149 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01854153 0,0334849 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,01854153 0,03346834 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,01854153 0,03345178 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,01854153 0,03343525 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01854153 0,03341873 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,01854153 0,03340223 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,01854153 0,03338574 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,01854153 0,03336927 ! response to vitamin A GO:0033189 18 14 0,000 0,01854153 0,03335281 ! actin filament bundle formation GO:0051017 16 14 0,000 0,01854153 0,03333638 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,01854153 0,03331995 ! plasma membrane fusion GO:0045026 15 14 0,000 0,01854153 0,03330355 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,01854153 0,03328716 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,01854153 0,03327079 ! protein export from nucleus GO:0006611 14 14 0,000 0,01854153 0,03325443 ! presynaptic membrane GO:0042734 14 14 0,000 0,01854153 0,03323809 ! negative regulation of immune response GO:0050777 21 14 0,000 0,01854153 0,03322176 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,01854153 0,03320545 ! neural crest cell migration GO:0001755 15 14 0,000 0,01854153 0,03318916 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,01854153 0,03317288 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,01854153 0,03315662 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,01854153 0,03314038 ! cofactor transport GO:0051181 16 14 0,000 0,01854153 0,03312415 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01854153 0,03310793 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,01854153 0,03309174 ! cobalt ion binding GO:0050897 14 14 0,000 0,01854153 0,03307555 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01854153 0,03305939 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,01854153 0,03304324 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,01854153 0,0330271 ! gas transport GO:0015669 15 14 0,000 0,01854153 0,03301098 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,01854153 0,03299488 ! heme biosynthetic process GO:0006783 14 14 0,000 0,01854153 0,03297879 ! cerebellar cortex development GO:0021695 16 14 0,000 0,01854153 0,03296272 ! insulin secretion GO:0030073 17 14 0,000 0,01854153 0,03294667 ! tRNA binding GO:0000049 16 14 0,000 0,01854153 0,03293063 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,01854153 0,0329146 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,01854153 0,03289859 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,01854153 0,0328826 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,01854153 0,03286662 ! regulation of B cell proliferation GO:0030888 18 14 0,000 0,01854153 0,03285066 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,01854153 0,03283471 ! MAP kinase activity GO:0004707 16 14 0,000 0,01854153 0,03281878 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,01854153 0,03280286 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,01854153 0,03278696 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,01854153 0,03277108 ! C-C chemokine binding GO:0019957 15 14 0,000 0,01854153 0,03275521 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,01854153 0,03273935 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,01854153 0,03272352 ! response to osmotic stress GO:0006970 17 14 0,000 0,01854153 0,03270769 ! fructose metabolic process GO:0006000 15 14 0,000 0,01854153 0,03269188 ! telomeric DNA binding GO:0042162 17 14 0,000 0,01854153 0,03267609 ! monoamine transport GO:0015844 15 14 0,000 0,01854153 0,03266031 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,01854153 0,03264455 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01854153 0,0326288 ! dendritic spine GO:0043197 15 14 0,000 0,01854153 0,03261307 ! stem cell development GO:0048864 14 14 0,000 0,01854153 0,03259735 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,01854153 0,03258165 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,01854153 0,03256596 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,01854153 0,03255029 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,01854153 0,03253464 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01854153 0,03251899 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,01854153 0,03250337 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01854153 0,03248776 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,01854153 0,03247216 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,01854153 0,03245658 ! mannosidase activity GO:0015923 19 14 0,000 0,01854153 0,03244101 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,01854153 0,03242546 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,01854153 0,03240992 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,01854153 0,0323944 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,01854153 0,03237889 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,01854153 0,0323634 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01854153 0,03234792 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,01854153 0,03233246 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,01854153 0,03231701 ! sperm-egg recognition GO:0035036 17 14 0,000 0,01854153 0,03230158 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,01854153 0,03228616 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,01854153 0,03227076 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,01854153 0,03225537 ! positive regulation of translation GO:0045727 17 15 0,000 0,01985322 0,03452076 ! nuclear replication fork GO:0043596 26 15 0,000 0,01985322 0,03450431 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,01985322 0,03448788 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,01985322 0,03447147 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,01985322 0,03445507 ! endothelial cell migration GO:0043542 16 15 0,000 0,01985322 0,03443868 ! lipid phosphorylation GO:0046834 19 15 0,000 0,01985322 0,03442231 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01985322 0,03440596 ! response to vitamin GO:0033273 19 15 0,000 0,01985322 0,03438962 ! gene silencing by RNA GO:0031047 17 15 0,000 0,01985322 0,0343733 ! striated muscle thick filament GO:0005863 16 15 0,000 0,01985322 0,034357 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,01985322 0,03434071 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,01985322 0,03432443 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,01985322 0,03430817 ! glutamate metabolic process GO:0006536 17 15 0,000 0,01985322 0,03429193 ! pituitary gland development GO:0021983 16 15 0,000 0,01985322 0,0342757 ! cholesterol binding GO:0015485 15 15 0,000 0,01985322 0,03425948 ! NAD metabolic process GO:0019674 17 15 0,000 0,01985322 0,03424329 ! protease binding GO:0002020 20 15 0,000 0,01985322 0,0342271 ! regulation of heart rate GO:0002027 20 15 0,000 0,01985322 0,03421094 ! actin filament bundle GO:0032432 18 15 0,000 0,01985322 0,03419478 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,01985322 0,03417865 ! regulation of exocytosis GO:0017157 16 15 0,000 0,01985322 0,03416252 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01985322 0,03414642 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,01985322 0,03413032 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,01985322 0,03411425 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,01985322 0,03409819 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,01985322 0,03408214 ! neuron recognition GO:0008038 18 15 0,000 0,01985322 0,03406611 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,01985322 0,03405009 ! filopodium GO:0030175 17 15 0,000 0,01985322 0,03403409 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,01985322 0,03401811 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,01985322 0,03400214 ! peptide hormone binding GO:0017046 16 15 0,000 0,01985322 0,03398618 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,01985322 0,03397024 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,01985322 0,03395431 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,01985322 0,0339384 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,01985322 0,03392251 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,01985322 0,03390662 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,01985322 0,03389076 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,01985322 0,03387491 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,01985322 0,03385907 ! developmental induction GO:0031128 17 15 0,000 0,01985322 0,03384325 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,01985322 0,03382744 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,01985322 0,03381165 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,01985322 0,03379587 ! lactation GO:0007595 17 15 0,000 0,01985322 0,03378011 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,01985322 0,03376436 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01985322 0,03374863 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01985322 0,03373291 ! double-strand break repair via homologous recombination GO:0000724 36 15 0,000 0,01985322 0,0337172 GO:0000725|recombinational repair, ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,01985322 0,03370151 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,01985322 0,03368584 ! sulfate transport GO:0008272 16 15 0,000 0,01985322 0,03367018 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,01985322 0,03365453 ! bile acid metabolic process GO:0008206 17 15 0,000 0,01985322 0,0336389 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,01985322 0,03362328 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,01985322 0,03360768 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,01985322 0,03359209 ! heart looping GO:0001947 18 15 0,000 0,01985322 0,03357652 ! protein kinase C activity GO:0004697 17 15 0,000 0,01985322 0,03356096 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,01985322 0,03354541 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,01985322 0,03352988 ! pigmentation during development GO:0048066 17 15 0,000 0,01985322 0,03351437 ! cytokine metabolic process GO:0042107 15 15 0,000 0,01985322 0,03349887 ! vesicle coating GO:0006901 17 15 0,000 0,01985322 0,03348338 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,01985322 0,03346791 ! neutral amino acid transport GO:0015804 18 15 0,000 0,01985322 0,03345245 ! L-amino acid transport GO:0015807 16 15 0,000 0,01985322 0,033437 ! microfilament motor activity GO:0000146 15 15 0,000 0,01985322 0,03342157 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,01985322 0,03340616 ! regulation of vasodilation GO:0042312 25 15 0,000 0,01985322 0,03339076 ! DNA replication initiation GO:0006270 15 15 0,000 0,01985322 0,03337537 ! taste receptor activity GO:0008527 15 15 0,000 0,01985322 0,03336 ! cellular pigmentation GO:0033059 16 15 0,000 0,01985322 0,03334464 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,01985322 0,03332929 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,01985322 0,03331396 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,01985322 0,03329864 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,01985322 0,03328334 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,01985322 0,03326805 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,01985322 0,03325278 ! ion gated channel activity GO:0022839 17 15 0,000 0,01985322 0,03323752 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,01985322 0,03322227 ! receptor activator activity GO:0030546 17 15 0,000 0,01985322 0,03320704 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,01985322 0,03319182 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,01985322 0,03317661 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,01985322 0,03316142 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,01985322 0,03314625 ! peptide hormone processing GO:0016486 19 15 0,000 0,01985322 0,03313108 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01985322 0,03311593 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,02116323 0,03528494 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,02116323 0,03526882 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,02116323 0,03525272 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,02116323 0,03523663 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,02116323 0,03522055 ! kinesin complex GO:0005871 16 16 0,000 0,02116323 0,03520449 ! photoreceptor cell development GO:0042461 22 16 0,000 0,02116323 0,03518845 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,02116323 0,03517242 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,02116323 0,0351564 ! centrosome cycle GO:0007098 26 16 0,000 0,02116323 0,0351404 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,02116323 0,03512441 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,02116323 0,03510844 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,02116323 0,03509248 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,02116323 0,03507653 ! lysosomal transport GO:0007041 16 16 0,000 0,02116323 0,03506061 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,02116323 0,03504469 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,02116323 0,03502879 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,02116323 0,0350129 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,02116323 0,03499703 ! myofibril assembly GO:0030239 17 16 0,000 0,02116323 0,03498117 GO:0055002|striated muscle cell development, ! G1 phase GO:0051318 17 16 0,000 0,02116323 0,03496533 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,02116323 0,0349495 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,02116323 0,03493369 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,02116323 0,03491789 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,02116323 0,0349021 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,02116323 0,03488633 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,02116323 0,03487057 ! steroid catabolic process GO:0006706 18 16 0,000 0,02116323 0,03485483 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,02116323 0,0348391 ! cell-cell recognition GO:0009988 19 16 0,000 0,02116323 0,03482339 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,02116323 0,03480769 ! spleen development GO:0048536 19 16 0,000 0,02116323 0,034792 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,02116323 0,03477633 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,02116323 0,03476067 ! neural tube closure GO:0001843 19 16 0,000 0,02116323 0,03474503 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,02116323 0,0347294 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,02116323 0,03471378 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,02116323 0,03469818 ! viral genome replication GO:0019079 16 16 0,000 0,02116323 0,03468259 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,02116323 0,03466702 ! memory GO:0007613 18 16 0,000 0,02116323 0,03465146 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,02116323 0,03463591 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02116323 0,03462038 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,02116323 0,03460486 ! glycoprotein binding GO:0001948 19 16 0,000 0,02116323 0,03458936 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,02116323 0,03457387 ! syntaxin binding GO:0019905 18 16 0,000 0,02116323 0,03455839 ! myosin binding GO:0017022 17 16 0,000 0,02116323 0,03454293 ! fucose metabolic process GO:0006004 18 16 0,000 0,02116323 0,03452748 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,02116323 0,03451205 ! membrane budding GO:0006900 18 16 0,000 0,02116323 0,03449663 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,02116323 0,03448122 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,02116323 0,03446583 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,02116323 0,03445045 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,02116323 0,03443508 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,02116323 0,03441973 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,02116323 0,03440439 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,02116323 0,03438907 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,02116323 0,03437375 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,02116323 0,03435846 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,02116323 0,03434317 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,02116323 0,0343279 ! axoneme GO:0005930 16 16 0,000 0,02116323 0,03431265 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,02116323 0,0342974 ! anion exchanger activity GO:0015380 17 17 0,000 0,02247155 0,03640152 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,02247155 0,03638536 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,02247155 0,03636922 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,02247155 0,03635309 ! glial cell development GO:0021782 17 17 0,000 0,02247155 0,03633698 ! limbic system development GO:0021761 18 17 0,000 0,02247155 0,03632088 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,02247155 0,03630479 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,02247155 0,03628872 ! ephrin receptor activity GO:0005003 21 17 0,000 0,02247155 0,03627267 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,02247155 0,03625662 ! glutamine metabolic process GO:0006541 26 17 0,000 0,02247155 0,03624059 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,02247155 0,03622458 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,02247155 0,03620858 ! signal sequence binding GO:0005048 18 17 0,000 0,02247155 0,03619259 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,02247155 0,03617662 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,02247155 0,03616066 ! organelle subcompartment GO:0031984 19 17 0,000 0,02247155 0,03614472 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,02247155 0,03612879 ! membrane depolarization GO:0051899 19 17 0,000 0,02247155 0,03611287 ! oogenesis GO:0048477 20 17 0,000 0,02247155 0,03609697 ! nuclear outer membrane GO:0005640 21 17 0,000 0,02247155 0,03608108 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,02247155 0,03606521 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,02247155 0,03604935 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,02247155 0,03603351 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,02247155 0,03601767 ! organic cation transport GO:0015695 17 17 0,000 0,02247155 0,03600186 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,02247155 0,03598605 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,02247155 0,03597026 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,02247155 0,03595448 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,02247155 0,03593872 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,02247155 0,03592297 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,02247155 0,03590724 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,02247155 0,03589152 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02247155 0,03587581 ! lipid localization GO:0010876 19 17 0,000 0,02247155 0,03586012 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,02247155 0,03584444 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,02247155 0,03582877 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,02247155 0,03581312 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,02247155 0,03579748 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,02247155 0,03578185 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,02247155 0,03576624 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,02247155 0,03575064 ! response to hexose stimulus GO:0009746 20 17 0,000 0,02247155 0,03573506 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,02247155 0,03571949 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,02247155 0,03570393 ! AMP binding GO:0016208 19 17 0,000 0,02247155 0,03568839 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,02247155 0,03567286 ! receptor metabolic process GO:0043112 20 17 0,000 0,02247155 0,03565734 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,02247155 0,03564184 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,02247155 0,03562635 ! alcohol binding GO:0043178 20 17 0,000 0,02247155 0,03561087 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,02247155 0,03559541 ! visual learning GO:0008542 31 17 0,000 0,02247155 0,03557996 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,02247155 0,03556452 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,02247155 0,0355491 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,02247155 0,03553369 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,02247155 0,03551829 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,02247155 0,03550291 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,02247155 0,03548754 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,02247155 0,03547219 ! translation elongation factor activity GO:0003746 19 17 0,000 0,02247155 0,03545684 ! histone binding GO:0042393 26 17 0,000 0,02247155 0,03544151 ! cilium assembly GO:0042384 18 17 0,000 0,02247155 0,0354262 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,02247155 0,0354109 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,02247155 0,03539561 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,02247155 0,03538033 ! protein secretion GO:0009306 19 18 0,000 0,0237782 0,03742143 ! positive regulation of ossification GO:0045778 19 18 0,000 0,0237782 0,03740529 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,0237782 0,03738917 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,0237782 0,03737306 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,0237782 0,03735696 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,0237782 0,03734088 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,0237782 0,03732482 ! cAMP metabolic process GO:0046058 18 18 0,000 0,0237782 0,03730876 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,0237782 0,03729272 ! cornified envelope GO:0001533 22 18 0,000 0,0237782 0,0372767 ! retinoid metabolic process GO:0001523 19 18 0,000 0,0237782 0,03726068 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,0237782 0,03724468 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,0237782 0,0372287 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,0237782 0,03721273 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,0237782 0,03719677 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,0237782 0,03718083 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,0237782 0,0371649 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,0237782 0,03714898 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,0237782 0,03713308 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,0237782 0,03711719 ! primary neural tube formation GO:0014020 21 18 0,000 0,0237782 0,03710131 ! recycling endosome GO:0055037 22 18 0,000 0,0237782 0,03708545 ! muscle cell development GO:0055001 20 18 0,000 0,0237782 0,0370696 ! kinase activator activity GO:0019209 22 18 0,000 0,0237782 0,03705377 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,0237782 0,03703795 ! cerebellum development GO:0021549 20 18 0,000 0,0237782 0,03702214 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,0237782 0,03700634 ! somitogenesis GO:0001756 20 18 0,000 0,0237782 0,03699056 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,0237782 0,0369748 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,0237782 0,03695904 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,0237782 0,0369433 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,0237782 0,03692757 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,0237782 0,03691186 ! basal plasma membrane GO:0009925 21 18 0,000 0,0237782 0,03689616 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,0237782 0,03688047 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,0237782 0,0368648 ! regulation of cell killing GO:0031341 24 18 0,000 0,0237782 0,03684914 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,0237782 0,03683349 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,0237782 0,03681786 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,0237782 0,03680224 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,0237782 0,03678663 ! protein complex scaffold GO:0032947 22 18 0,000 0,0237782 0,03677103 ! SNAP receptor activity GO:0005484 21 18 0,000 0,0237782 0,03675545 ! dendrite development GO:0016358 22 18 0,000 0,0237782 0,03673989 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,0237782 0,03672433 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,0237782 0,03670879 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,0237782 0,03669326 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,0237782 0,03667775 ! nuclear ubiquitin ligase complex GO:0000152 31 18 0,000 0,0237782 0,03666224 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,0237782 0,03664676 ! coreceptor activity GO:0015026 28 18 0,000 0,0237782 0,03663128 ! response to fungus GO:0009620 18 18 0,000 0,0237782 0,03661582 ! stem cell differentiation GO:0048863 18 18 0,000 0,0237782 0,03660037 ! intermediate filament-based process GO:0045103 18 18 0,000 0,0237782 0,03658493 ! heart process GO:0003015 19 18 0,000 0,0237782 0,03656951 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,0237782 0,0365541 ! vasodilation GO:0042311 20 18 0,000 0,0237782 0,0365387 ! transport vesicle membrane GO:0030658 23 18 0,000 0,0237782 0,03652331 ! MHC protein binding GO:0042287 30 18 0,000 0,0237782 0,03650794 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,0237782 0,03649258 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,0237782 0,03647724 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,0237782 0,0364619 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,0237782 0,03644658 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,0237782 0,03643128 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,0237782 0,03641598 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,0237782 0,0364007 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,0237782 0,03638543 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,02508317 0,03836621 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,02508317 0,03835013 ! proteasome core complex GO:0005839 20 19 0,000 0,02508317 0,03833406 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,02508317 0,03831801 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,02508317 0,03830197 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,02508317 0,03828594 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,02508317 0,03826993 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,02508317 0,03825393 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,02508317 0,03823794 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,02508317 0,03822197 ! lysosome organization GO:0007040 20 19 0,000 0,02508317 0,03820601 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,02508317 0,03819007 ! central nervous system neuron development GO:0021954 21 19 0,000 0,02508317 0,03817413 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,02508317 0,03815822 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,02508317 0,03814231 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,02508317 0,03812642 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,02508317 0,03811054 ! peptide cross-linking GO:0018149 23 19 0,000 0,02508317 0,03809467 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,02508317 0,03807882 ! beta-catenin binding GO:0008013 23 19 0,000 0,02508317 0,03806298 ! cell projection membrane GO:0031253 21 19 0,000 0,02508317 0,03804715 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02508317 0,03803134 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,02508317 0,03801554 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,02508317 0,03799975 ! vitamin transport GO:0051180 21 19 0,000 0,02508317 0,03798398 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,02508317 0,03796822 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,02508317 0,03795247 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,02508317 0,03793673 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,02508317 0,03792101 ! retinoid binding GO:0005501 19 19 0,000 0,02508317 0,0379053 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,02508317 0,03788961 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,02508317 0,03787392 ! histone deacetylase activity GO:0004407 20 19 0,000 0,02508317 0,03785825 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,02508317 0,0378426 ! gluconeogenesis GO:0006094 23 19 0,000 0,02508317 0,03782695 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,02508317 0,03781132 ! microtubule-based transport GO:0010970 20 19 0,000 0,02508317 0,0377957 ! superoxide metabolic process GO:0006801 21 19 0,000 0,02508317 0,0377801 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,02508317 0,03776451 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02508317 0,03774893 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,02508317 0,03773336 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,02508317 0,03771781 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,02508317 0,03770227 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,02508317 0,03768674 ! acetylcholine binding GO:0042166 20 19 0,000 0,02508317 0,03767122 ! heme metabolic process GO:0042168 20 19 0,000 0,02508317 0,03765572 ! SH2 domain binding GO:0042169 25 19 0,000 0,02508317 0,03764023 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,02508317 0,03762475 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,02508317 0,03760929 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,02508317 0,03759384 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,02508317 0,0375784 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,02508317 0,03756297 ! body fluid secretion GO:0007589 21 19 0,000 0,02508317 0,03754756 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,02508317 0,03753216 ! secretory granule membrane GO:0030667 21 19 0,000 0,02508317 0,03751677 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,02508317 0,03750139 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,02508317 0,03748603 ! peptidase activator activity GO:0016504 21 19 0,000 0,02508317 0,03747068 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02508317 0,03745534 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,02508317 0,03744002 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,02508317 0,0374247 ! sialyltransferase activity GO:0008373 31 19 0,000 0,02508317 0,0374094 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,02508317 0,03739412 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,02638646 0,03932101 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,02638646 0,03930495 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,02638646 0,03928891 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,02638646 0,03927288 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,02638646 0,03925686 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,02638646 0,03924086 ! ovarian follicle development GO:0001541 21 20 0,000 0,02638646 0,03922487 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 0,000 0,02638646 0,03920889 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,02638646 0,03919292 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,02638646 0,03917697 ! diencephalon development GO:0021536 22 20 0,000 0,02638646 0,03916103 ! regulation of lipid transport GO:0032368 22 20 0,000 0,02638646 0,03914511 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,02638646 0,0391292 ! glutathione metabolic process GO:0006749 21 20 0,000 0,02638646 0,0391133 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,02638646 0,03909741 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,02638646 0,03908154 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,02638646 0,03906567 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,02638646 0,03904983 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,02638646 0,03903399 ! peptide hormone secretion GO:0030072 25 20 0,000 0,02638646 0,03901817 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,02638646 0,03900236 ! Rab GTPase binding GO:0017137 22 20 0,000 0,02638646 0,03898656 ! initiation of viral infection GO:0019059 22 20 0,000 0,02638646 0,03897078 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,02638646 0,03895501 ! heterochromatin GO:0000792 20 20 0,000 0,02638646 0,03893925 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,02638646 0,0389235 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,02638646 0,03890777 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,02638646 0,03889205 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,02638646 0,03887634 ! visual behavior GO:0007632 34 20 0,000 0,02638646 0,03886065 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,02638646 0,03884496 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,02638646 0,03882929 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,02638646 0,03881364 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,02638646 0,03879799 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,02638646 0,03878236 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,02638646 0,03876674 ! rRNA binding GO:0019843 22 20 0,000 0,02638646 0,03875114 ! cytolysis GO:0019835 22 20 0,000 0,02638646 0,03873554 ! renal system process GO:0003014 22 20 0,000 0,02638646 0,03871996 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,02638646 0,03870439 ! fatty acid transport GO:0015908 23 20 0,000 0,02638646 0,03868883 ! transaminase activity GO:0008483 22 20 0,000 0,02638646 0,03867329 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,02638646 0,03865776 ! collagen catabolic process GO:0030574 21 20 0,000 0,02638646 0,03864224 ! microvillus GO:0005902 25 20 0,000 0,02638646 0,03862673 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,02638646 0,03861124 ! connexon complex GO:0005922 23 20 0,000 0,02638646 0,03859576 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,02768809 0,04048342 ! translational initiation GO:0006413 21 21 0,000 0,02768809 0,0404672 ! NF-kappaB binding GO:0051059 31 21 0,000 0,02768809 0,040451 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,02768809 0,0404348 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,02768809 0,04041862 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,02768809 0,04040246 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,02768809 0,0403863 ! glutathione transferase activity GO:0004364 21 21 0,000 0,02768809 0,04037016 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,02768809 0,04035403 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,02768809 0,04033792 ! regeneration GO:0031099 24 21 0,000 0,02768809 0,04032181 ! MHC class I protein complex GO:0042612 31 21 0,000 0,02768809 0,04030572 ! cellular response to starvation GO:0009267 22 21 0,000 0,02768809 0,04028964 ! peroxisome organization GO:0007031 22 21 0,000 0,02768809 0,04027358 ! vacuole organization GO:0007033 23 21 0,000 0,02768809 0,04025753 ! apoptotic nuclear changes GO:0030262 24 21 0,000 0,02768809 0,04024149 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,02768809 0,04022546 ! neural crest cell development GO:0014032 24 21 0,000 0,02768809 0,04020945 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,02768809 0,04019345 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,02768809 0,04017746 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,02768809 0,04016149 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02768809 0,04014552 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,02768809 0,04012957 ! pallium development GO:0021543 22 21 0,000 0,02768809 0,04011364 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,02768809 0,04009771 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 0,000 0,02768809 0,0400818 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,02768809 0,0400659 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,02768809 0,04005002 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,02768809 0,04003414 ! cyclase activity GO:0009975 22 21 0,000 0,02768809 0,04001828 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,02768809 0,04000243 ! gut development GO:0048565 23 21 0,000 0,02768809 0,0399866 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,02768809 0,03997077 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,02768809 0,03995496 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02768809 0,03993916 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,02768809 0,03992338 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02768809 0,0399076 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,02768809 0,03989184 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,02768809 0,03987609 ! axis specification GO:0009798 25 21 0,000 0,02768809 0,03986035 ! response to alkaloid GO:0043279 27 21 0,000 0,02768809 0,03984463 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,02768809 0,03982892 ! response to ethanol GO:0045471 28 21 0,000 0,02768809 0,03981322 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,02768809 0,03979753 ! smooth muscle contraction GO:0006939 25 21 0,000 0,02768809 0,03978186 ! ubiquitin binding GO:0043130 25 21 0,000 0,02768809 0,0397662 ! vesicle targeting GO:0006903 22 21 0,000 0,02768809 0,03975055 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,02768809 0,03973491 ! SNARE binding GO:0000149 24 21 0,000 0,02768809 0,03971928 ! interaction with host GO:0051701 26 21 0,000 0,02768809 0,03970367 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,02768809 0,03968807 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,02768809 0,03967248 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,02768809 0,03965691 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,02768809 0,03964134 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,02768809 0,03962579 ! cell-cell junction organization GO:0045216 24 21 0,000 0,02768809 0,03961025 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,02768809 0,03959472 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,02768809 0,03957921 ! caveola GO:0005901 25 21 0,000 0,02768809 0,03956371 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,02768809 0,03954821 ! insulin receptor binding GO:0005158 25 21 0,000 0,02768809 0,03953274 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02768809 0,03951727 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02768809 0,03950181 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,02898804 0,04134025 ! metencephalon development GO:0022037 25 22 0,000 0,02898804 0,0413241 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,02898804 0,04130795 ! hormone secretion GO:0046879 28 22 0,000 0,02898804 0,04129182 ! vesicle docking GO:0048278 24 22 0,000 0,02898804 0,04127571 ! muscle myosin complex GO:0005859 23 22 0,000 0,02898804 0,0412596 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,02898804 0,04124351 ! actomyosin structure organization GO:0031032 24 22 0,000 0,02898804 0,04122743 ! microtubule organizing center organization GO:0031023 33 22 0,000 0,02898804 0,04121137 GO:0051297|centrosome organization, ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,02898804 0,04119531 ! sperm motility GO:0030317 23 22 0,000 0,02898804 0,04117927 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,02898804 0,04116324 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,02898804 0,04114722 ! vacuolar transport GO:0007034 22 22 0,000 0,02898804 0,04113122 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,02898804 0,04111523 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,02898804 0,04109925 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,02898804 0,04108328 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,02898804 0,04106733 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,02898804 0,04105138 GO:0004950|chemokine receptor activity, ! PML body GO:0016605 25 22 0,000 0,02898804 0,04103545 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,02898804 0,04101954 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,02898804 0,04100363 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,02898804 0,04098774 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,02898804 0,04097186 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,02898804 0,04095599 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,02898804 0,04094013 ! deacetylase activity GO:0019213 23 22 0,000 0,02898804 0,04092429 ! pentose metabolic process GO:0019321 23 22 0,000 0,02898804 0,04090846 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,02898804 0,04089264 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,02898804 0,04087683 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,02898804 0,04086104 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,02898804 0,04084525 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! positive regulation of B cell activation GO:0050871 26 22 0,000 0,02898804 0,04082948 ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,02898804 0,04081373 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,02898804 0,04079798 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,02898804 0,04078225 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,02898804 0,04076652 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,02898804 0,04075081 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,02898804 0,04073512 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,02898804 0,04071943 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,02898804 0,04070376 ! glycerol metabolic process GO:0006071 24 22 0,000 0,02898804 0,0406881 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,02898804 0,04067245 ! nuclear chromatin GO:0000790 23 22 0,000 0,02898804 0,04065681 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,02898804 0,04064118 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,02898804 0,04062557 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,02898804 0,04060997 ! sterol binding GO:0032934 24 22 0,000 0,02898804 0,04059438 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,02898804 0,0405788 ! digestive system process GO:0022600 25 22 0,000 0,02898804 0,04056324 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,02898804 0,04054769 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,02898804 0,04053214 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,02898804 0,04051661 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,02898804 0,0405011 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,02898804 0,04048559 ! DNA modification GO:0006304 25 22 0,000 0,02898804 0,0404701 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,02898804 0,04045461 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,02898804 0,04043914 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,02898804 0,04042369 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,02898804 0,04040824 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,02898804 0,0403928 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,02898804 0,04037738 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,02898804 0,04036197 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,02898804 0,04034657 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,03028632 0,04213749 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,03028632 0,04212143 ! leukocyte adhesion GO:0007159 26 23 0,000 0,03028632 0,04210537 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,03028632 0,04208933 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,03028632 0,04207331 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,03028632 0,04205729 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,03028632 0,04204129 ! ureteric bud development GO:0001657 24 23 0,000 0,03028632 0,04202529 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,03028632 0,04200932 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,03028632 0,04199335 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,03028632 0,04197739 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,03028632 0,04196145 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,03028632 0,04194552 ! deaminase activity GO:0019239 24 23 0,000 0,03028632 0,0419296 ! sensory perception of pain GO:0019233 26 23 0,000 0,03028632 0,0419137 ! lipid kinase activity GO:0001727 26 23 0,000 0,03028632 0,0418978 ! platelet activation GO:0030168 27 23 0,000 0,03028632 0,04188192 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,03028632 0,04186605 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,03028632 0,04185019 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,03028632 0,04183434 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,03028632 0,04181851 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,03028632 0,04180269 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,03028632 0,04178688 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,03028632 0,04177108 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,03028632 0,04175529 ! regulation of glucose import GO:0046324 28 23 0,000 0,03028632 0,04173952 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,03028632 0,04172375 ! alditol metabolic process GO:0019400 25 23 0,000 0,03028632 0,041708 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,03028632 0,04169226 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,03028632 0,04167654 ! zinc ion transport GO:0006829 26 23 0,000 0,03028632 0,04166082 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,03028632 0,04164512 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,03028632 0,04162943 ! sex determination GO:0007530 25 23 0,000 0,03028632 0,04161375 ! phosphate binding GO:0042301 25 23 0,000 0,03028632 0,04159808 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,03028632 0,04158242 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,03028632 0,04156678 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,03028632 0,04155115 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,03028632 0,04153553 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,03028632 0,04151992 ! positive regulation of nuclear division GO:0051785 35 23 0,000 0,03028632 0,04150432 GO:0045840|positive regulation of mitosis, ! synaptogenesis GO:0007416 25 23 0,000 0,03028632 0,04148873 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,03028632 0,04147316 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,03028632 0,0414576 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,03028632 0,04144205 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,03028632 0,04142651 ! leukocyte proliferation GO:0070661 26 23 0,000 0,03028632 0,04141098 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,03028632 0,04139547 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,03158294 0,04315152 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,03158294 0,04313536 ! pancreas development GO:0031016 27 24 0,000 0,03158294 0,04311922 ! androgen receptor binding GO:0050681 34 24 0,000 0,03158294 0,04310309 ! calcium channel complex GO:0034704 31 24 0,000 0,03158294 0,04308697 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,03158294 0,04307086 ! negative regulation of cell development GO:0010721 30 24 0,000 0,03158294 0,04305477 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,03158294 0,04303868 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,03158294 0,04302261 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,03158294 0,04300655 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,03158294 0,04299051 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,03158294 0,04297447 ! Rho GTPase binding GO:0017048 36 24 0,000 0,03158294 0,04295845 ! regulation of glucose transport GO:0010827 29 24 0,000 0,03158294 0,04294244 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,03158294 0,04292644 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,03158294 0,04291045 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,03158294 0,04289447 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,03158294 0,04287851 ! protein stabilization GO:0050821 24 24 0,000 0,03158294 0,04286256 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,03158294 0,04284662 ! embryonic pattern specification GO:0009880 29 24 0,000 0,03158294 0,04283069 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,03158294 0,04281477 ! RNA polymerase complex GO:0030880 25 24 0,000 0,03158294 0,04279887 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,03158294 0,04278298 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,03158294 0,0427671 ! small conjugating protein binding GO:0032182 29 24 0,000 0,03158294 0,04275123 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,03158294 0,04273537 ! chemokine binding GO:0019956 26 24 0,000 0,03158294 0,04271952 ! catechol metabolic process GO:0009712 29 24 0,000 0,03158294 0,04270369 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,03158294 0,04268787 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,03158294 0,04267206 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,03158294 0,04265626 ! cell aging GO:0007569 47 24 0,000 0,03158294 0,04264047 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,03158294 0,0426247 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,03158294 0,04260893 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,03158294 0,04259318 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,03158294 0,04257744 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,03158294 0,04256171 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,03158294 0,042546 ! caspase regulator activity GO:0043028 26 24 0,000 0,03158294 0,04253029 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 0,000 0,03158294 0,0425146 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,03158294 0,04249891 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,03158294 0,04248324 ! selenium binding GO:0008430 24 24 0,000 0,03158294 0,04246758 ! spindle pole GO:0000922 35 24 0,000 0,03158294 0,04245194 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,03158294 0,0424363 ! phenol metabolic process GO:0018958 31 25 0,000 0,03287789 0,04415999 ! protein amino acid acylation GO:0043543 28 25 0,000 0,03287789 0,04414374 ! aromatase activity GO:0070330 28 25 0,000 0,03287789 0,0441275 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,03287789 0,04411127 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,03287789 0,04409505 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,03287789 0,04407885 ! response to starvation GO:0042594 26 25 0,000 0,03287789 0,04406265 ! dynein complex GO:0030286 28 25 0,000 0,03287789 0,04404647 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,03287789 0,0440303 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,03287789 0,04401414 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,03287789 0,043998 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,03287789 0,04398186 ! hormone transport GO:0009914 31 25 0,000 0,03287789 0,04396574 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,03287789 0,04394963 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,03287789 0,04393353 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03287789 0,04391745 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,03287789 0,04390137 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,03287789 0,04388531 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,03287789 0,04386926 ! molting cycle process GO:0022404 28 25 0,000 0,03287789 0,04385322 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,03287789 0,04383719 ! phototransduction GO:0007602 27 25 0,000 0,03287789 0,04382117 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,03287789 0,04380517 ! protein phosphatase binding GO:0019903 27 25 0,000 0,03287789 0,04378917 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,03287789 0,04377319 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,03287789 0,04375722 ! autophagy GO:0006914 28 25 0,000 0,03287789 0,04374126 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,03287789 0,04372532 ! response to ionizing radiation GO:0010212 37 25 0,000 0,03287789 0,04370938 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,03287789 0,04369346 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,03417118 0,04539565 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,03417118 0,04537913 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,03417118 0,04536261 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,03417118 0,04534611 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,03417118 0,04532962 ! hair cycle GO:0042633 29 26 0,000 0,03417118 0,04531315 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,03417118 0,04529668 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,03417118 0,04528023 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,03417118 0,04526379 ! early endosome membrane GO:0031901 31 26 0,000 0,03417118 0,04524736 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,03417118 0,04523094 ! iron ion homeostasis GO:0055072 29 26 0,000 0,03417118 0,04521453 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,03417118 0,04519814 ! GABA receptor activity GO:0016917 31 26 0,000 0,03417118 0,04518176 ! PDZ domain binding GO:0030165 28 26 0,000 0,03417118 0,04516539 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,03417118 0,04514903 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,03417118 0,04513268 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,03417118 0,04511635 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,03417118 0,04510002 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,03417118 0,04508371 ! fatty acid binding GO:0005504 28 26 0,000 0,03417118 0,04506741 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,03417118 0,04505113 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,03417118 0,04503485 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,03417118 0,04501859 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,03417118 0,04500233 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,03417118 0,04498609 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,03417118 0,04496986 ! iron ion transport GO:0006826 33 26 0,000 0,03417118 0,04495365 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,03417118 0,04493744 ! glucose transport GO:0015758 27 26 0,000 0,03417118 0,04492125 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,03417118 0,04490507 ! spinal cord development GO:0021510 30 26 0,000 0,03417118 0,0448889 ! histone deacetylase complex GO:0000118 29 26 0,000 0,03417118 0,04487274 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,03417118 0,04485659 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,03417118 0,04484045 ! RNA helicase activity GO:0003724 46 26 0,000 0,03417118 0,04482433 ! brush border GO:0005903 30 26 0,000 0,03417118 0,04480822 ! gap junction GO:0005921 29 26 0,000 0,03417118 0,04479212 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,03417118 0,04477603 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,03546281 0,04645182 ! mRNA catabolic process GO:0006402 31 27 0,000 0,03546281 0,04643515 ! myelination GO:0042552 31 27 0,000 0,03546281 0,04641849 ! trans-Golgi network GO:0005802 31 27 0,000 0,03546281 0,04640184 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,03546281 0,0463852 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,03546281 0,04636858 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,03546281 0,04635196 ! vasculogenesis GO:0001570 32 27 0,000 0,03546281 0,04633536 ! hexose transport GO:0008645 28 27 0,000 0,03546281 0,04631877 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,03546281 0,04630219 ! spindle organization GO:0007051 38 27 0,000 0,03546281 0,04628563 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,03546281 0,04626907 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,03546281 0,04625253 ! cell fate determination GO:0001709 29 27 0,000 0,03546281 0,046236 ! lipid oxidation GO:0034440 29 27 0,000 0,03546281 0,04621948 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,03546281 0,04620297 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,03546281 0,04618648 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,03546281 0,04617 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,03546281 0,04615352 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,03546281 0,04613706 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,03546281 0,04612062 ! membrane docking GO:0022406 29 27 0,000 0,03546281 0,04610418 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,03546281 0,04608776 GO:0050908|detection of light stimulus involved in visual perception, ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,03546281 0,04607134 ! phospholipid transport GO:0015914 29 27 0,000 0,03546281 0,04605494 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,03546281 0,04603855 ! aminopeptidase activity GO:0004177 33 27 0,000 0,03546281 0,04602217 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,03546281 0,04600581 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,03546281 0,04598945 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,03546281 0,04597311 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,03546281 0,04595678 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,03546281 0,04594046 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,03675278 0,04759466 ! Golgi stack GO:0005795 30 28 0,000 0,03675278 0,04757777 ! male gonad development GO:0008584 32 28 0,000 0,03675278 0,04756089 ! regulation of fatty acid metabolic process GO:0019217 41 28 0,000 0,03675278 0,04754402 ! lipoprotein binding GO:0008034 31 28 0,000 0,03675278 0,04752717 ! mesoderm formation GO:0001707 34 28 0,000 0,03675278 0,04751033 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,03675278 0,0474935 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,03675278 0,04747668 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,03675278 0,04745987 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,03675278 0,04744308 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,03675278 0,0474263 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,03675278 0,04740953 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,03675278 0,04739277 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,03675278 0,04737602 ! tissue homeostasis GO:0001894 31 28 0,000 0,03675278 0,04735929 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,03675278 0,04734256 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,03675278 0,04732585 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,03675278 0,04730915 ! sister chromatid segregation GO:0000819 49 28 0,000 0,03675278 0,04729247 ! post-embryonic development GO:0009791 32 28 0,000 0,03675278 0,04727579 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,03675278 0,04725913 ! negative regulation of phosphorylation GO:0042326 30 28 0,000 0,03675278 0,04724247 ! detection of visible light GO:0009584 30 28 0,000 0,03675278 0,04722583 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,03675278 0,04720921 ! receptor regulator activity GO:0030545 31 28 0,000 0,03675278 0,04719259 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,03675278 0,04717598 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,03675278 0,04715939 ! response to heat GO:0009408 33 28 0,000 0,03675278 0,04714281 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,03675278 0,04712624 ! hormone binding GO:0042562 31 29 0,000 0,0380411 0,04876104 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,0380411 0,04874391 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,0380411 0,0487268 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,0380411 0,04870969 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,0380411 0,0486926 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,0380411 0,04867552 ! ceramide metabolic process GO:0006672 29 29 0,000 0,0380411 0,04865846 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,0380411 0,0486414 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,0380411 0,04862436 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,0380411 0,04860733 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,0380411 0,04859031 ! regulation of pH GO:0006885 30 29 0,000 0,0380411 0,0485733 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,0380411 0,0485563 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,0380411 0,04853932 ! phospholipase C activity GO:0004629 43 29 0,000 0,0380411 0,04852235 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,0380411 0,04850539 ! sodium channel activity GO:0005272 33 29 0,000 0,0380411 0,04848844 ! sarcoplasm GO:0016528 31 29 0,000 0,0380411 0,0484715 ! detection of light stimulus GO:0009583 31 29 0,000 0,0380411 0,04845458 ! spermatid development GO:0007286 30 29 0,000 0,0380411 0,04843767 ! DNA polymerase activity GO:0034061 34 29 0,000 0,0380411 0,04842077 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,0380411 0,04840388 ! sarcolemma GO:0042383 30 29 0,000 0,0380411 0,048387 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,0380411 0,04837013 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,0380411 0,04835328 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,0380411 0,04833644 ! cholesterol transport GO:0030301 33 30 0,000 0,03932776 0,04995392 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,03932776 0,04993653 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,03932776 0,04991916 ! scavenger receptor activity GO:0005044 39 30 0,000 0,03932776 0,04990179 ! spliceosome assembly GO:0000245 34 30 0,000 0,03932776 0,04988444 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,03932776 0,0498671 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,03932776 0,04984978 ! metanephros development GO:0001656 31 30 0,000 0,03932776 0,04983246 ! glutamate receptor activity GO:0008066 35 30 0,000 0,03932776 0,04981516 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,03932776 0,04979787 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,03932776 0,04978059 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,03932776 0,04976332 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,03932776 0,04974607 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,03932776 0,04972882 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,03932776 0,04971159 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,03932776 0,04969437 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,03932776 0,04967717 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,03932776 0,04965997 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,03932776 0,04964279 ! protein-lipid complex GO:0032994 41 30 0,000 0,03932776 0,04962562 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,03932776 0,04960846 ! phosphatase binding GO:0019902 34 30 0,000 0,03932776 0,04959131 ! acute-phase response GO:0006953 44 30 0,000 0,03932776 0,04957417 ! segmentation GO:0035282 37 30 0,000 0,03932776 0,04955705 ! response to toxin GO:0009636 33 30 0,000 0,03932776 0,04953994 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,03932776 0,04952284 ! antigen binding GO:0003823 33 30 0,000 0,03932776 0,04950575 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,03932776 0,04948867 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,03932776 0,0494716 ! ensheathment of neurons GO:0007272 35 30 0,000 0,03932776 0,04945455 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,03932776 0,04943751 ! regulation of microtubule-based process GO:0032886 41 30 0,000 0,03932776 0,04942048 ! vesicle localization GO:0051648 31 30 0,000 0,03932776 0,04940346 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,04061276 0,05100013 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,04061276 0,05098258 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 0,000 0,04061276 0,05096504 GO:0045936|negative regulation of phosphate metabolic process, ! acrosomal vesicle GO:0001669 34 31 0,000 0,04061276 0,05094751 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,04061276 0,05093 ! protein targeting to membrane GO:0006612 35 31 0,000 0,04061276 0,0509125 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,04061276 0,05089501 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,04061276 0,05087753 ! formation of primary germ layer GO:0001704 37 31 0,000 0,04061276 0,05086006 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,04061276 0,05084261 ! endocytic vesicle GO:0030139 33 31 0,000 0,04061276 0,05082517 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,04061276 0,05080774 ! spermatid differentiation GO:0048515 32 31 0,000 0,04061276 0,05079032 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,04061276 0,05077291 ! neuron fate commitment GO:0048663 44 31 0,000 0,04061276 0,05075552 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,04061276 0,05073814 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,04061276 0,05072077 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,04061276 0,05070341 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,04061276 0,05068606 ! cell junction assembly GO:0034329 36 31 0,000 0,04061276 0,05066873 ! drug binding GO:0008144 34 31 0,000 0,04061276 0,05065141 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,04061276 0,0506341 ! peptide transport GO:0015833 36 31 0,000 0,04061276 0,0506168 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,04061276 0,05059951 ! peripheral nervous system development GO:0007422 35 31 0,000 0,04061276 0,05058223 ! I band GO:0031674 34 31 0,000 0,04061276 0,05056497 ! BMP signaling pathway GO:0030509 33 31 0,000 0,04061276 0,05054772 ! adult locomotory behavior GO:0008344 37 31 0,000 0,04061276 0,05053048 ! gene silencing GO:0016458 33 31 0,000 0,04061276 0,05051325 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,04189612 0,0520917 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,04189612 0,05207395 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,04189612 0,05205622 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,04189612 0,05203849 ! meiosis I GO:0007127 53 32 0,000 0,04189612 0,05202078 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,04189612 0,05200308 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,04189612 0,05198539 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,04189612 0,05196772 ! vesicle coat GO:0030120 39 32 0,000 0,04189612 0,05195005 ! cytokine production GO:0001816 32 32 0,000 0,04189612 0,0519324 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,04189612 0,05191476 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,04189612 0,05189713 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,04189612 0,05187952 ! oxygen binding GO:0019825 33 32 0,000 0,04189612 0,05186191 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,04189612 0,05184432 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,04189612 0,05182674 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,04189612 0,05180917 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,04189612 0,05179161 ! microtubule organizing center part GO:0044450 46 32 0,000 0,04189612 0,05177407 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,04317783 0,0533399 ! DNA helicase activity GO:0003678 55 33 0,000 0,04317783 0,05332185 ! neural tube development GO:0021915 37 33 0,000 0,04317783 0,0533038 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,04317783 0,05328577 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,04317783 0,05326775 ! organelle envelope lumen GO:0031970 46 33 0,000 0,04317783 0,05324974 ! regulation of cellular ketone metabolic process GO:0010565 46 33 0,000 0,04317783 0,05323174 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,04317783 0,05321376 ! NAD or NADH binding GO:0051287 36 33 0,000 0,04317783 0,05319579 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,04317783 0,05317783 ! B cell differentiation GO:0030183 37 33 0,000 0,04317783 0,05315988 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 0,000 0,04317783 0,05314195 ! aerobic respiration GO:0009060 35 33 0,000 0,04317783 0,05312402 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,04317783 0,05310611 ! tissue remodeling GO:0048771 37 33 0,000 0,04317783 0,05308821 ! flagellum GO:0019861 34 33 0,000 0,04317783 0,05307033 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,04317783 0,05305245 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,04317783 0,05303459 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,04317783 0,05301674 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,0444579 0,05457012 ! lipid homeostasis GO:0055088 37 34 0,000 0,0444579 0,05455177 ! telencephalon development GO:0021537 36 34 0,000 0,0444579 0,05453343 ! clathrin coat GO:0030118 41 34 0,000 0,0444579 0,05451509 ! regulation of B cell activation GO:0050864 40 34 0,000 0,0444579 0,05449678 ! protein polymerization GO:0051258 38 34 0,000 0,0444579 0,05447847 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,0444579 0,05446018 ! learning GO:0007612 51 34 0,000 0,0444579 0,0544419 ! keratinization GO:0031424 40 34 0,000 0,0444579 0,05442363 ! ovulation cycle process GO:0022602 35 34 0,000 0,0444579 0,05440537 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,0444579 0,05438712 ! steroid hormone receptor binding GO:0035258 44 34 0,000 0,0444579 0,05436889 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,0444579 0,05435067 ! amino acid binding GO:0016597 40 34 0,000 0,0444579 0,05433246 ! regulation of protein stability GO:0031647 35 34 0,000 0,0444579 0,05431427 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,0444579 0,05429609 ! glycogen metabolic process GO:0005977 48 34 0,000 0,0444579 0,05427791 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,0444579 0,05425975 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,0444579 0,05424161 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,0444579 0,05422347 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,04573632 0,05576406 GO:0090047|positive regulation of transcription regulator activity, ! response to estrogen stimulus GO:0043627 48 35 0,000 0,04573632 0,05574543 ! inner ear morphogenesis GO:0042472 46 35 0,000 0,04573632 0,05572681 ! MHC protein complex GO:0042611 50 35 0,000 0,04573632 0,05570821 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,04573632 0,05568961 ! female gonad development GO:0008585 37 35 0,000 0,04573632 0,05567103 ! mesenchymal cell development GO:0014031 40 35 0,000 0,04573632 0,05565246 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,04573632 0,05563391 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,04573632 0,05561536 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,04573632 0,05559683 ! regulation of proteolysis GO:0030162 37 35 0,000 0,04573632 0,05557831 ! ovulation cycle GO:0042698 37 35 0,000 0,04573632 0,0555598 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,04573632 0,05554131 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,04573632 0,05552282 ! glucan metabolic process GO:0044042 49 35 0,000 0,04573632 0,05550435 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,04573632 0,05548589 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,04573632 0,05546745 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,04573632 0,05544901 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,04573632 0,05543059 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,04573632 0,05541218 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,04573632 0,05539379 ! maintenance of protein location GO:0045185 45 35 0,000 0,04573632 0,0553754 ! polyol metabolic process GO:0019751 46 35 0,000 0,04573632 0,05535703 ! androgen receptor signaling pathway GO:0030521 47 35 0,000 0,04573632 0,05533867 ! cytokinesis GO:0000910 38 35 0,000 0,04573632 0,05532032 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,04573632 0,05530198 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,04701309 0,05682696 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,04701309 0,05680814 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,04701309 0,05678933 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,04701309 0,05677053 ! SMAD binding GO:0046332 39 36 0,000 0,04701309 0,05675174 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,04701309 0,05673297 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,04701309 0,05671421 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,04701309 0,05669546 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,04701309 0,05667672 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,04701309 0,056658 ! nucleus organization GO:0006997 42 36 0,000 0,04701309 0,05663929 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 0,000 0,04701309 0,05662059 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,04701309 0,0566019 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,04701309 0,05658323 ! cellular response to extracellular stimulus GO:0031668 37 36 0,000 0,04701309 0,05656457 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,04701309 0,05654592 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,04701309 0,05652728 ! positive regulation of mast cell proliferation GO:0070668 43 36 0,000 0,04701309 0,05650865 GO:0050671|positive regulation of lymphocyte proliferation, ! maintenance of location in cell GO:0051651 38 36 0,000 0,04701309 0,05649004 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,04828823 0,05800312 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,04828823 0,05798403 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,04828823 0,05796495 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,04828823 0,05794588 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,04828823 0,05792682 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,04828823 0,05790778 ! endoribonuclease activity GO:0004521 48 37 0,000 0,04828823 0,05788875 ! hindbrain development GO:0030902 43 37 0,000 0,04828823 0,05786973 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,04828823 0,05785073 ! pigmentation GO:0043473 51 37 0,000 0,04828823 0,05783174 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,04828823 0,05781276 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,04828823 0,05779379 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,04828823 0,05777483 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,04828823 0,05775589 ! sensory perception of taste GO:0050909 37 37 0,000 0,04828823 0,05773696 ! cell junction organization GO:0034330 44 37 0,000 0,04828823 0,05771804 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,04828823 0,05769914 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,04828823 0,05768025 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,04828823 0,05766136 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,04828823 0,0576425 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,04828823 0,05762364 ! coated pit GO:0005905 44 37 0,000 0,04828823 0,0576048 ! positive regulation of leukocyte proliferation GO:0070665 47 37 0,000 0,04828823 0,05758597 GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,04956173 0,05908536 ! regulation of translational initiation GO:0006446 50 38 0,000 0,04956173 0,05906606 ! negative regulation of binding GO:0051100 44 38 0,000 0,04956173 0,05904677 ! organic ether metabolic process GO:0018904 50 38 0,000 0,04956173 0,05902749 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,04956173 0,05900822 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,04956173 0,05898897 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,04956173 0,05896973 ! hydro-lyase activity GO:0016836 44 38 0,000 0,04956173 0,0589505 ! synapse organization GO:0050808 43 38 0,000 0,04956173 0,05893129 ! viral infectious cycle GO:0019058 40 38 0,000 0,04956173 0,05891209 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,04956173 0,0588929 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,04956173 0,05887372 ! organic anion transport GO:0015711 42 38 0,000 0,04956173 0,05885456 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,04956173 0,0588354 ! monosaccharide binding GO:0048029 41 38 0,000 0,04956173 0,05881626 ! muscle fiber development GO:0048747 42 38 0,000 0,04956173 0,05879714 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,04956173 0,05877802 ! phagocytosis GO:0006909 44 38 0,000 0,04956173 0,05875892 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,04956173 0,05873983 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,04956173 0,05872075 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,04956173 0,05870169 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,04956173 0,05868263 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,04956173 0,05866359 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,04956173 0,05864457 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,04956173 0,05862555 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,05083359 0,06011052 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,05083359 0,06009104 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,05083359 0,06007158 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,05083359 0,06005212 ! T cell differentiation GO:0030217 64 39 0,000 0,05083359 0,06003268 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,05083359 0,06001325 ! cell fate specification GO:0001708 55 39 0,000 0,05083359 0,05999384 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,05083359 0,05997444 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,05083359 0,05995505 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,05083359 0,05993567 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,05083359 0,0599163 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,05083359 0,05989695 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,05083359 0,05987761 ! amine receptor activity GO:0008227 48 39 0,000 0,05083359 0,05985828 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,05083359 0,05983897 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,05083359 0,05981966 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,05083359 0,05980037 ! double-strand break repair GO:0006302 70 39 0,000 0,05083359 0,05978109 ! pigment metabolic process GO:0042440 43 39 0,000 0,05083359 0,05976183 ! RNA modification GO:0009451 39 39 0,000 0,05083359 0,05974258 ! damaged DNA binding GO:0003684 51 40 0,000 0,05210382 0,0612157 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,05210382 0,06119599 ! peroxisomal membrane GO:0005778 44 40 0,000 0,05210382 0,0611763 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,05210382 0,06115661 ! positive regulation of cell development GO:0010720 43 40 0,000 0,05210382 0,06113694 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,05210382 0,06111728 ! biopolymer methylation GO:0043414 45 40 0,000 0,05210382 0,06109764 ! neuron migration GO:0001764 43 40 0,000 0,05210382 0,06107801 ! regulation of protein secretion GO:0050708 45 40 0,000 0,05210382 0,06105838 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,05210382 0,06103878 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,05210382 0,06101918 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,05210382 0,0609996 ! positive regulation of defense response GO:0031349 41 40 0,000 0,05210382 0,06098003 ! mammary gland development GO:0030879 47 40 0,000 0,05210382 0,06096047 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,05210382 0,06094093 ! neuropeptide binding GO:0042923 42 40 0,000 0,05210382 0,06092139 ! regulation of tube size GO:0035150 44 40 0,000 0,05210382 0,06090188 GO:0050880|regulation of blood vessel size, ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,05210382 0,06088237 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,05210382 0,06086287 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,05210382 0,06084339 ! chromatin remodeling GO:0006338 44 40 0,000 0,05210382 0,06082392 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,05210382 0,06080446 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,05337242 0,06226498 ! Notch signaling pathway GO:0007219 46 41 0,000 0,05337242 0,06224508 ! keratin filament GO:0045095 44 41 0,000 0,05337242 0,06222518 ! peptide metabolic process GO:0006518 42 41 0,000 0,05337242 0,0622053 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,05337242 0,06218543 ! late endosome membrane GO:0031902 45 41 0,000 0,05337242 0,06216558 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,05337242 0,06214574 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,05337242 0,06212591 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,05337242 0,06210609 ! glycolysis GO:0006096 43 41 0,000 0,05337242 0,06208629 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,05337242 0,0620665 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,05337242 0,06204672 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,05337242 0,06202695 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,05463939 0,06347914 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,05463939 0,06345893 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,05463939 0,06343873 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,05463939 0,06341855 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,05463939 0,06339838 ! developmental growth GO:0048589 45 42 0,000 0,05463939 0,06337822 ! structural constituent of muscle GO:0008307 46 42 0,000 0,05463939 0,06335807 ! mitochondrial transport GO:0006839 45 42 0,000 0,05463939 0,06333794 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,05463939 0,06331782 ! metal cluster binding GO:0051540 47 42 0,000 0,05463939 0,06329771 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,05463939 0,06327762 ! protein serine/threonine phosphatase activity GO:0004722 45 42 0,000 0,05463939 0,06325754 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,05463939 0,06323747 ! RNA catabolic process GO:0006401 49 43 0,000 0,05590473 0,0646814 ! ear morphogenesis GO:0042471 56 43 0,000 0,05590473 0,06466089 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,05590473 0,0646404 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,05590473 0,06461992 ! cell recognition GO:0008037 51 43 0,000 0,05590473 0,06459945 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,05590473 0,06457899 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,05590473 0,06455855 ! gliogenesis GO:0042063 46 43 0,000 0,05590473 0,06453812 ! endosome transport GO:0016197 48 43 0,000 0,05590473 0,0645177 ! striated muscle contraction GO:0006941 45 43 0,000 0,05590473 0,0644973 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,05590473 0,06447691 ! antioxidant activity GO:0016209 53 43 0,000 0,05590473 0,06445653 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,05590473 0,06443616 ! activation of caspase activity GO:0006919 60 43 0,000 0,05590473 0,06441581 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,05590473 0,06439547 ! histone modification GO:0016570 45 43 0,000 0,05590473 0,06437514 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,05590473 0,06435483 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,05716844 0,0657888 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,05716844 0,06576805 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,05716844 0,06574731 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,05716844 0,06572659 ! chemokine activity GO:0008009 48 44 0,000 0,05716844 0,06570589 ! ruffle GO:0001726 50 44 0,000 0,05716844 0,06568519 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,05716844 0,06566451 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,05716844 0,06564384 ! cartilage development GO:0051216 48 44 0,000 0,05716844 0,06562318 ! membrane fusion GO:0006944 52 44 0,000 0,05716844 0,06560254 ! channel regulator activity GO:0016247 54 44 0,000 0,05716844 0,06558191 ! excretion GO:0007588 53 44 0,000 0,05716844 0,0655613 ! male sex differentiation GO:0046661 52 44 0,000 0,05716844 0,06554069 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,05716844 0,0655201 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,05716844 0,06549952 ! amino acid activation GO:0043038 45 44 0,000 0,05716844 0,06547896 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,05716844 0,06545841 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,05843053 0,06688252 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,05843053 0,06686154 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,05843053 0,06684057 ! organellar ribosome GO:0000313 46 45 0,000 0,05843053 0,06681962 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,05843053 0,06679868 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,05843053 0,06677775 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,05843053 0,06675684 ! transport vesicle GO:0030133 53 45 0,000 0,05843053 0,06673594 ! regulation of endocytosis GO:0030100 52 45 0,000 0,05843053 0,06671505 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,05843053 0,06669418 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,05843053 0,06667331 ! nuclear matrix GO:0016363 56 45 0,000 0,05843053 0,06665247 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,05843053 0,06663163 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,05843053 0,06661081 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,05843053 0,06659 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,05843053 0,0665692 ! coated vesicle membrane GO:0030662 52 45 0,000 0,05843053 0,06654842 ! covalent chromatin modification GO:0016569 47 45 0,000 0,05843053 0,06652765 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,05843053 0,06650689 ! synaptosome GO:0019717 50 45 0,000 0,05843053 0,06648615 ! chemokine receptor binding GO:0042379 50 45 0,000 0,05843053 0,06646541 ! regulation of action potential GO:0001508 56 46 0,000 0,059691 0,06787805 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,059691 0,06785689 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,059691 0,06783575 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,059691 0,06781463 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,059691 0,06779352 ! methylation GO:0032259 51 46 0,000 0,059691 0,06777242 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,059691 0,06775133 ! regulation of ion transport GO:0043269 54 46 0,000 0,059691 0,06773026 ! leukocyte migration GO:0050900 49 46 0,000 0,059691 0,0677092 ! neuromuscular process GO:0050905 56 46 0,000 0,059691 0,06768815 ! sulfotransferase activity GO:0008146 54 46 0,000 0,059691 0,06766711 ! JNK cascade GO:0007254 48 46 0,000 0,059691 0,06764609 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,059691 0,06762508 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,06094985 0,06902982 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,06094985 0,0690084 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,06094985 0,06898698 ! microtubule binding GO:0008017 61 47 0,000 0,06094985 0,06896559 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,06094985 0,0689442 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,06094985 0,06892283 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,06094985 0,06890147 ! viral reproductive process GO:0022415 53 47 0,000 0,06094985 0,06888013 ! RNA elongation GO:0006354 52 47 0,000 0,06094985 0,06885879 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,06094985 0,06883748 ! mRNA binding GO:0003729 65 47 0,000 0,06094985 0,06881617 ! axon GO:0030424 53 48 0,000 0,06220708 0,07021393 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,06220708 0,07019221 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,06220708 0,07017051 ! proteasome complex GO:0000502 50 48 0,000 0,06220708 0,07014882 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,06220708 0,07012714 ! protein homooligomerization GO:0051260 63 48 0,000 0,06220708 0,07010548 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,06220708 0,07008382 ! kinetochore GO:0000776 69 48 0,000 0,06220708 0,07006219 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,06220708 0,07004056 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,06220708 0,07001895 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,06220708 0,06999735 ! inner ear development GO:0048839 60 48 0,000 0,06220708 0,06997577 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,06220708 0,0699542 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,06220708 0,06993264 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,06220708 0,0699111 ! B cell mediated immunity GO:0019724 53 48 0,000 0,06220708 0,06988957 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,06220708 0,06986805 ! regulation of cell shape GO:0008360 55 48 0,000 0,06220708 0,06984654 ! establishment of organelle localization GO:0051656 58 48 0,000 0,06220708 0,06982505 ! cell cortex part GO:0044448 54 48 0,000 0,06220708 0,06980358 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,06346269 0,07119062 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,06346269 0,07116874 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,06346269 0,07114687 ! response to temperature stimulus GO:0009266 57 49 0,000 0,06346269 0,07112501 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,06346269 0,07110316 ! lipid modification GO:0030258 55 49 0,000 0,06346269 0,07108133 ! synaptic vesicle GO:0008021 56 49 0,000 0,06346269 0,07105952 ! regulation of gene expression, epigenetic GO:0040029 64 49 0,000 0,06346269 0,07103771 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,06346269 0,07101592 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,06346269 0,07099414 ! maintenance of location GO:0051235 62 49 0,000 0,06346269 0,07097238 ! regulation of actin filament length GO:0030832 62 49 0,000 0,06346269 0,07095063 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,06346269 0,07092889 ! negative regulation of cytoskeleton organization GO:0051494 73 49 0,000 0,06346269 0,07090717 ! regulation of mast cell proliferation GO:0070666 57 49 0,000 0,06346269 0,07088546 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,06471669 0,072264 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,06471669 0,07224189 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,06471669 0,07221979 ! glucose catabolic process GO:0006007 54 50 0,000 0,06471669 0,0721977 ! aging GO:0007568 92 50 0,000 0,06471669 0,07217563 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,06471669 0,07215357 ! heart morphogenesis GO:0003007 57 50 0,000 0,06471669 0,07213153 ! integrin binding GO:0005178 56 50 0,000 0,06471669 0,0721095 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,06471669 0,07208748 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,06596908 0,07346008 ! regulation of ossification GO:0030278 59 51 0,000 0,06596908 0,07343766 ! positive regulation of organelle organization GO:0010638 69 51 0,000 0,06596908 0,07341526 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,06596908 0,07339287 ! endocrine system development GO:0035270 55 51 0,000 0,06596908 0,07337049 ! germ cell development GO:0007281 56 51 0,000 0,06596908 0,07334813 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,06721986 0,07471604 ! regulation of cellular component size GO:0032535 66 52 0,000 0,06721986 0,07469328 ! carbohydrate transport GO:0008643 57 52 0,000 0,06721986 0,07467054 ! regulation of lymphocyte proliferation GO:0050670 61 52 0,000 0,06721986 0,07464781 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,06721986 0,07462509 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,06721986 0,07460239 ! cell maturation GO:0048469 68 52 0,000 0,06721986 0,0745797 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,06721986 0,07455702 ! vesicle organization GO:0016050 59 52 0,000 0,06721986 0,07453436 ! kidney development GO:0001822 55 52 0,000 0,06721986 0,07451171 ! cellular component disassembly GO:0022411 69 52 0,000 0,06721986 0,07448908 ! cell redox homeostasis GO:0045454 57 52 0,000 0,06721986 0,07446646 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,06721986 0,07444385 ! lipid transporter activity GO:0005319 58 52 0,000 0,06721986 0,07442126 ! cytokine receptor activity GO:0004896 54 52 0,000 0,06721986 0,07439868 ! antiporter activity GO:0015297 53 52 0,000 0,06721986 0,07437611 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,06846903 0,0757353 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,06846903 0,07571234 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,06846903 0,0756894 ! basement membrane GO:0005604 55 53 0,000 0,06846903 0,07566647 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,06846903 0,07564355 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,06846903 0,07562065 ! viral reproduction GO:0016032 59 53 0,000 0,06846903 0,07559777 ! chloride transport GO:0006821 60 53 0,000 0,06846903 0,07557489 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,06846903 0,07555203 ! regulation of protein catabolic process GO:0042176 56 53 0,000 0,06846903 0,07552919 ! DNA catabolic process GO:0006308 57 53 0,000 0,06846903 0,07550635 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,06846903 0,07548353 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,06846903 0,07546073 ! regulation of leukocyte proliferation GO:0070663 65 53 0,000 0,06846903 0,07543794 GO:0032944|regulation of mononuclear cell proliferation, ! single fertilization GO:0007338 58 53 0,000 0,06846903 0,07541516 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,06971659 0,07676611 GO:0010863|positive regulation of phospholipase C activity, ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,06971659 0,07674295 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,06971659 0,0767198 ! coated membrane GO:0048475 65 54 0,000 0,06971659 0,07669666 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,06971659 0,07667354 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,06971659 0,07665043 ! cellular defense response GO:0006968 61 54 0,000 0,06971659 0,07662734 ! gastrulation GO:0007369 62 54 0,000 0,06971659 0,07660426 ! dendrite GO:0030425 60 55 0,000 0,07096255 0,07794983 ! regulation of mitosis GO:0007088 79 55 0,000 0,07096255 0,07792637 GO:0051783|regulation of nuclear division, ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,07096255 0,07790292 ! respiratory chain GO:0070469 57 55 0,000 0,07096255 0,07787948 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,07096255 0,07785606 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,07096255 0,07783265 ! translation initiation factor activity GO:0003743 66 55 0,000 0,07096255 0,07780925 ! steroid hormone receptor signaling pathway GO:0030518 70 55 0,000 0,07096255 0,07778587 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,07220691 0,07912611 ! heat shock protein binding GO:0031072 62 56 0,000 0,07220691 0,07910234 ! late endosome GO:0005770 60 56 0,000 0,07220691 0,0790786 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,07220691 0,07905486 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,07220691 0,07903115 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,07220691 0,07900744 ! ribonuclease activity GO:0004540 67 56 0,000 0,07220691 0,07898375 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,07220691 0,07896007 ! mesoderm development GO:0007498 67 56 0,000 0,07220691 0,07893641 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,07220691 0,07891276 ! antigen processing and presentation GO:0019882 73 56 0,000 0,07220691 0,07888913 ! proton transport GO:0015992 59 56 0,000 0,07220691 0,07886551 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,07344967 0,08019886 ! chromosome segregation GO:0007059 92 57 0,000 0,07344967 0,08017486 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,07344967 0,08015088 ! diacylglycerol binding GO:0019992 65 57 0,000 0,07344967 0,08012691 ! B cell activation GO:0042113 63 57 0,000 0,07344967 0,08010296 ! small ribosomal subunit GO:0015935 58 57 0,000 0,07344967 0,08007902 ! detection of external stimulus GO:0009581 64 57 0,000 0,07344967 0,08005509 ! occluding junction GO:0070160 75 58 0,000 0,07469083 0,08138355 GO:0005923|tight junction, ! hydrogen transport GO:0006818 61 58 0,000 0,07469083 0,08135925 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,07469083 0,08133497 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,07469083 0,08131069 ! large ribosomal subunit GO:0015934 64 58 0,000 0,07469083 0,08128644 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,07469083 0,08126219 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,07469083 0,08123797 ! myosin complex GO:0016459 64 58 0,000 0,07469083 0,08121375 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,07593039 0,08253697 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,07593039 0,08251238 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,07593039 0,08248781 ! actin filament organization GO:0007015 65 59 0,000 0,07593039 0,08246325 ! regulation of heart contraction GO:0008016 71 59 0,000 0,07593039 0,08243871 ! hexose catabolic process GO:0019320 64 59 0,000 0,07593039 0,08241418 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,07593039 0,08238967 ! regulation of cellular response to stress GO:0080135 79 59 0,000 0,07593039 0,08236517 ! appendage morphogenesis GO:0035107 68 59 0,000 0,07593039 0,08234068 GO:0035108|limb morphogenesis, ! fertilization GO:0009566 65 59 0,000 0,07593039 0,08231621 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,07593039 0,08229176 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,07593039 0,08226732 ! adult behavior GO:0030534 72 59 0,000 0,07593039 0,08224289 ! organelle localization GO:0051640 70 59 0,000 0,07593039 0,08221848 ! positive regulation of secretion GO:0051047 66 60 0,000 0,07716836 0,08353418 ! molecular adaptor activity GO:0060090 73 60 0,000 0,07716836 0,0835094 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,07716836 0,08348463 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,07716836 0,08345988 ! copper ion binding GO:0005507 85 60 0,000 0,07716836 0,08343514 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,07716836 0,08341042 ! activation of immune response GO:0002253 72 60 0,000 0,07716836 0,08338571 ! cell cycle checkpoint GO:0000075 91 60 0,000 0,07716836 0,08336102 ! appendage development GO:0048736 69 60 0,000 0,07716836 0,08333635 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,07716836 0,08331168 ! secondary metabolic process GO:0019748 67 60 0,000 0,07716836 0,08328703 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,07840474 0,08459641 ! ear development GO:0043583 76 61 0,000 0,07840474 0,0845714 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,07840474 0,0845464 ! learning or memory GO:0007611 79 61 0,000 0,07840474 0,08452142 ! Ras GTPase binding GO:0017016 78 61 0,000 0,07840474 0,08449645 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,07840474 0,08447149 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,07963952 0,08577649 GO:0090046|regulation of transcription regulator activity, ! lysosomal membrane GO:0005765 69 62 0,000 0,07963952 0,08575117 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,07963952 0,08572587 ! nuclear pore GO:0005643 79 62 0,000 0,07963952 0,08570058 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,07963952 0,08567531 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,07963952 0,08565005 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,07963952 0,08562481 ! chloride channel activity GO:0005254 72 62 0,000 0,07963952 0,08559958 ! cell soma GO:0043025 68 62 0,000 0,07963952 0,08557437 ! microtubule motor activity GO:0003777 94 62 0,000 0,07963952 0,08554917 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 0,000 0,07963952 0,08552399 ! focal adhesion GO:0005925 72 62 0,000 0,07963952 0,08549882 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,07963952 0,08547366 ! negative regulation of cell growth GO:0030308 69 63 0,000 0,08087272 0,08677167 ! FAD binding GO:0050660 71 63 0,000 0,08087272 0,08674616 ! urogenital system development GO:0001655 75 63 0,000 0,08087272 0,08672066 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,08087272 0,08669518 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,08087272 0,08666971 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,08087272 0,08664425 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,08087272 0,08661882 ! regulation of immune effector process GO:0002697 81 63 0,000 0,08087272 0,08659339 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,08210433 0,08788633 ! tRNA processing GO:0008033 73 64 0,000 0,08210433 0,08786055 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,08210433 0,08783478 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,08210433 0,08780903 ! adaptive immune response GO:0002250 70 64 0,000 0,08210433 0,0877833 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,08210433 0,08775758 ! neurotransmitter transport GO:0006836 72 64 0,000 0,08210433 0,08773187 ! nuclear hormone receptor binding GO:0035257 79 64 0,000 0,08210433 0,08770618 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,08210433 0,0876805 ! negative regulation of cell size GO:0045792 71 65 0,000 0,08333436 0,08896803 ! lymphocyte differentiation GO:0030098 93 65 0,000 0,08333436 0,088942 ! positive regulation of lymphocyte activation GO:0051251 83 65 0,000 0,08333436 0,08891598 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,08333436 0,08888998 ! activation of MAPK activity GO:0000187 74 65 0,000 0,08333436 0,088864 ! gonad development GO:0008406 71 65 0,000 0,08333436 0,08883803 ! acetyltransferase activity GO:0016407 73 65 0,000 0,08333436 0,08881208 ! protein import into nucleus GO:0006606 73 66 0,000 0,0845628 0,09009495 ! developmental maturation GO:0021700 85 66 0,000 0,0845628 0,09006865 ! tubulin binding GO:0015631 92 66 0,000 0,0845628 0,09004236 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,0845628 0,09001608 ! tube morphogenesis GO:0035239 84 66 0,000 0,0845628 0,08998982 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,0845628 0,08996358 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,0845628 0,08993735 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,08578967 0,0912156 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,08578967 0,09118902 ! nuclear import GO:0051170 74 67 0,000 0,08578967 0,09116246 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,08578967 0,09113591 ! chloride ion binding GO:0031404 79 67 0,000 0,08578967 0,09110938 ! humoral immune response GO:0006959 75 67 0,000 0,08578967 0,09108286 ! amine binding GO:0043176 77 67 0,000 0,08578967 0,09105636 ! extrinsic to membrane GO:0019898 75 67 0,000 0,08578967 0,09102988 ! anion channel activity GO:0005253 77 67 0,000 0,08578967 0,09100341 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,08578967 0,09097695 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,08701496 0,09224951 ! amine catabolic process GO:0009310 73 68 0,000 0,08701496 0,09222271 ! negative regulation of organelle organization GO:0010639 93 68 0,000 0,08701496 0,09219592 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,08701496 0,09216915 ! cell-substrate junction GO:0030055 78 68 0,000 0,08701496 0,0921424 ! mRNA transport GO:0051028 88 69 0,000 0,08823866 0,0934111 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,08823866 0,093384 ! small GTPase binding GO:0031267 86 69 0,000 0,08823866 0,09335692 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,08823866 0,09332985 ! sarcomere GO:0030017 74 69 0,000 0,08823866 0,0933028 ! exocytosis GO:0006887 76 69 0,000 0,08823866 0,09327576 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,08823866 0,09324874 GO:0060538|skeletal muscle organ development, ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,08823866 0,09322173 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,08823866 0,09319474 ! amine biosynthetic process GO:0009309 78 70 0,000 0,0894608 0,09445818 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,0894608 0,09443084 ! early endosome GO:0005769 104 70 0,000 0,0894608 0,09440353 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,0894608 0,09437623 ! regulation of lipase activity GO:0060191 78 70 0,000 0,0894608 0,09434894 ! amino acid transport GO:0006865 76 70 0,000 0,0894608 0,09432167 ! hormone receptor binding GO:0051427 85 70 0,000 0,0894608 0,09429442 ! calcium channel activity GO:0005262 86 70 0,000 0,0894608 0,09426719 ! axon guidance GO:0007411 87 70 0,000 0,0894608 0,09423996 ! nuclear chromosome part GO:0044454 94 70 0,000 0,0894608 0,09421276 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,09068136 0,09547059 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,09068136 0,09544305 ! protein localization in nucleus GO:0034504 78 71 0,000 0,09068136 0,09541552 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,09068136 0,09538801 ! pore complex GO:0046930 89 72 0,000 0,09190035 0,0966424 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,09190035 0,09661455 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,09190035 0,09658671 ! regulation of lyase activity GO:0051339 85 72 0,000 0,09190035 0,0965589 ! acute inflammatory response GO:0002526 91 72 0,000 0,09190035 0,09653109 ! apical junction complex GO:0043296 90 72 0,000 0,09190035 0,09650331 ! phospholipase activity GO:0004620 99 72 0,000 0,09190035 0,09647554 ! membrane raft GO:0045121 81 72 0,000 0,09190035 0,09644778 ! regulation of neurological system process GO:0031644 91 72 0,000 0,09190035 0,09642004 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,09190035 0,09639232 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,09311777 0,09764117 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,09311777 0,09761312 ! protein transporter activity GO:0008565 80 73 0,000 0,09311777 0,09758507 ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,09311777 0,09755705 ! exopeptidase activity GO:0008238 81 73 0,000 0,09311777 0,09752904 ! digestion GO:0007586 81 73 0,000 0,09311777 0,09750105 ! positive regulation of leukocyte activation GO:0002696 92 73 0,000 0,09311777 0,09747307 ! cell-matrix adhesion GO:0007160 102 74 0,000 0,09433363 0,09871746 ! potassium channel complex GO:0034705 84 74 0,000 0,09433363 0,09868915 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,09433363 0,09866086 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,09433363 0,09863258 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,09433363 0,09860432 ! blood coagulation GO:0007596 90 74 0,000 0,09433363 0,09857608 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,09433363 0,09854785 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,09433363 0,09851963 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,09433363 0,09849144 ! ubiquitin ligase complex GO:0000151 91 74 0,000 0,09433363 0,09846326 ! cell projection part GO:0044463 80 74 0,000 0,09433363 0,09843509 ! meiosis GO:0007126 108 75 0,000 0,09554792 0,09967367 GO:0051327|M phase of meiotic cell cycle, ! regulation of DNA binding GO:0051101 94 75 0,000 0,09554792 0,09964517 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,09554792 0,09961669 ! regulation of cell cycle process GO:0010564 113 75 0,000 0,09554792 0,09958823 ! positive regulation of cell activation GO:0050867 94 75 0,000 0,09554792 0,09955979 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,09554792 0,09953136 ! regulation of blood pressure GO:0008217 82 75 0,000 0,09554792 0,09950294 ! transcription initiation GO:0006352 84 75 0,000 0,09554792 0,09947455 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,09554792 0,09944617 ! neuropeptide signaling pathway GO:0007218 85 76 0,000 0,09676065 0,10067965 ! negative regulation of growth GO:0045926 85 76 0,000 0,09676065 0,10065094 ! defense response to bacterium GO:0042742 81 76 0,000 0,09676065 0,10062225 ! meiotic cell cycle GO:0051321 109 76 0,000 0,09676065 0,10059357 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,09676065 0,10056491 ! condensed chromosome GO:0000793 106 76 0,000 0,09676065 0,10053627 ! protein-DNA complex GO:0032993 93 76 0,000 0,09676065 0,10050764 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,09676065 0,10047903 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,09676065 0,10045044 ! cytosolic ribosome GO:0022626 82 76 0,000 0,09676065 0,10042186 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,09676065 0,1003933 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,09797181 0,10162103 ! alcohol catabolic process GO:0046164 84 77 0,000 0,09797181 0,10159215 ! vacuolar membrane GO:0005774 86 77 0,000 0,09797181 0,10156328 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,09797181 0,10153443 ! myofibril GO:0030016 82 77 0,000 0,09797181 0,10150559 ! protein oligomerization GO:0051259 93 77 0,000 0,09797181 0,10147677 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,09918142 0,10270049 ! endonuclease activity GO:0004519 111 78 0,000 0,09918142 0,10267135 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,09918142 0,10264222 ! inorganic anion transport GO:0015698 87 78 0,000 0,09918142 0,10261311 ! regulation of protein transport GO:0051223 85 78 0,000 0,09918142 0,10258402 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,09918142 0,10255494 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,09918142 0,10252588 ! carboxylesterase activity GO:0004091 93 78 0,000 0,09918142 0,10249683 ! protein ubiquitination GO:0016567 95 78 0,000 0,09918142 0,10246781 ! contractile fiber part GO:0044449 83 78 0,000 0,09918142 0,10243879 ! vitamin metabolic process GO:0006766 86 79 0,000 0,10038947 0,10365717 ! T cell activation GO:0042110 120 79 0,000 0,10038947 0,10362784 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,10038947 0,10359853 ! phosphoinositide binding GO:0035091 99 79 0,000 0,10038947 0,10356923 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,10159597 0,1047843 ! rhythmic process GO:0048511 90 80 0,000 0,10159597 0,10475469 ! regulation of catabolic process GO:0009894 87 80 0,000 0,10159597 0,10472509 ! SH3 domain binding GO:0017124 95 80 0,000 0,10159597 0,1046955 ! hemostasis GO:0007599 96 80 0,000 0,10159597 0,10466594 ! chromosome, centromeric region GO:0000775 119 80 0,000 0,10159597 0,10463639 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,10159597 0,10460685 ! cell-substrate adhesion GO:0031589 109 80 0,000 0,10159597 0,10457734 ! rRNA processing GO:0006364 84 80 0,000 0,10159597 0,10454784 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,10280091 0,10575795 ! vacuolar part GO:0044437 91 81 0,000 0,10280091 0,10572814 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,1040043 0,10693565 ! forebrain development GO:0030900 93 82 0,000 0,1040043 0,10690551 ! external side of plasma membrane GO:0009897 105 82 0,000 0,1040043 0,1068754 ! cellular respiration GO:0045333 85 82 0,000 0,1040043 0,1068453 ! heparin binding GO:0008201 108 82 0,000 0,1040043 0,10681522 ! microtubule-based movement GO:0007018 119 83 0,000 0,10520614 0,10801913 ! nuclear speck GO:0016607 99 83 0,000 0,10520614 0,10798874 ! rRNA metabolic process GO:0016072 88 83 0,000 0,10520614 0,10795836 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,10520614 0,107928 GO:0070035|purine NTP-dependent helicase activity, ! regulation of T cell activation GO:0050863 104 83 0,000 0,10520614 0,10789766 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,10520614 0,10786734 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,10520614 0,10783703 ! contractile fiber GO:0043292 88 83 0,000 0,10520614 0,10780674 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,10520614 0,10777646 ! regulation of membrane potential GO:0042391 98 83 0,000 0,10520614 0,10774621 ! cilium GO:0005929 88 83 0,000 0,10520614 0,10771597 ! regulation of defense response GO:0031347 98 84 0,000 0,10640643 0,10891432 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,10640643 0,10888377 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,10640643 0,10885324 ! DNA recombination GO:0006310 147 84 0,000 0,10640643 0,10882272 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,10760517 0,11001785 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,10760517 0,10998702 ! monooxygenase activity GO:0004497 92 85 0,000 0,10760517 0,10995621 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,10760517 0,10992542 ! protein binding, bridging GO:0030674 104 85 0,000 0,10760517 0,10989465 ! negative regulation of transport GO:0051051 98 86 0,000 0,10880238 0,11108622 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,10880238 0,11105514 ! Golgi vesicle transport GO:0048193 98 86 0,000 0,10880238 0,11102408 ! lipase activity GO:0016298 114 86 0,000 0,10880238 0,11099303 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,10880238 0,110962 ! adherens junction GO:0005912 100 86 0,000 0,10880238 0,11093099 ! microtubule cytoskeleton organization GO:0000226 113 87 0,000 0,10999804 0,1121187 ! leukocyte differentiation GO:0002521 118 87 0,000 0,10999804 0,11208739 ! pigment granule GO:0048770 101 87 0,000 0,10999804 0,11205609 GO:0042470|melanosome, ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,10999804 0,1120248 ! organelle outer membrane GO:0031968 102 88 0,000 0,11119216 0,11320932 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,11119216 0,11317773 ! protein processing GO:0016485 100 88 0,000 0,11119216 0,11314616 ! protein tyrosine phosphatase activity GO:0004725 109 89 0,000 0,11238474 0,11432781 ! gland development GO:0048732 108 89 0,000 0,11238474 0,11429594 ! ATP metabolic process GO:0046034 100 90 0,000 0,11357579 0,11547505 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,11357579 0,11544287 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,11357579 0,11541072 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,11357579 0,11537858 ! sterol metabolic process GO:0016125 102 90 0,000 0,11357579 0,11534646 ! anion binding GO:0043168 104 90 0,000 0,11357579 0,11531435 ! amine transport GO:0015837 97 90 0,000 0,11357579 0,11528227 ! response to virus GO:0009615 109 90 0,000 0,11357579 0,1152502 ! outer membrane GO:0019867 104 90 0,000 0,11357579 0,11521815 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,1147653 0,1163925 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,1147653 0,11636015 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,1147653 0,11632782 ! sulfur metabolic process GO:0006790 98 91 0,000 0,1147653 0,1162955 ! sex differentiation GO:0007548 103 91 0,000 0,1147653 0,11626321 ! hormone metabolic process GO:0042445 107 91 0,000 0,1147653 0,11623093 ! regulation of protein localization GO:0032880 99 91 0,000 0,1147653 0,11619867 ! detection of stimulus GO:0051606 100 91 0,000 0,1147653 0,11616643 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,11595328 0,11733635 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,11595328 0,11730382 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,11595328 0,11727129 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,11595328 0,11723879 ! cell cycle arrest GO:0007050 103 93 0,000 0,11713973 0,11840558 ! protein import GO:0017038 102 93 0,000 0,11713973 0,11837278 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,11713973 0,11834 ! Ras protein signal transduction GO:0007265 118 93 0,000 0,11713973 0,11830723 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,11713973 0,11827449 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,11832465 0,11943783 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,11832465 0,11940479 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,11832465 0,11937177 GO:0060429|epithelium development, ! anchoring junction GO:0070161 108 94 0,000 0,11832465 0,11933876 ! neurotransmitter binding GO:0042165 105 94 0,000 0,11832465 0,11930578 ! homophilic cell adhesion GO:0007156 107 95 0,000 0,11950804 0,12046569 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,11950804 0,12043241 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,11950804 0,12039915 ! protein localization in organelle GO:0033365 104 95 0,000 0,11950804 0,12036591 ! Wnt receptor signaling pathway GO:0016055 121 95 0,000 0,11950804 0,12033269 ! immune effector process GO:0002252 110 95 0,000 0,11950804 0,12029948 ! apical plasma membrane GO:0016324 105 95 0,000 0,11950804 0,1202663 ! translational elongation GO:0006414 104 96 0,000 0,12068991 0,12142217 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,12068991 0,12138869 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,12068991 0,12135523 ! receptor complex GO:0043235 131 96 0,000 0,12068991 0,12132179 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,12068991 0,12128837 ! electron transport chain GO:0022900 104 97 0,000 0,12187025 0,12244084 ! microtubule associated complex GO:0005875 135 97 0,000 0,12187025 0,12240713 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,12187025 0,12237343 ! perinuclear region of cytoplasm GO:0048471 125 97 0,000 0,12187025 0,12233976 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,12187025 0,1223061 ! carboxylic acid binding GO:0031406 108 97 0,000 0,12187025 0,12227247 ! protein maturation GO:0051604 109 97 0,000 0,12187025 0,12223885 ! intermediate filament GO:0005882 102 98 0,000 0,12304908 0,12338731 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,12304908 0,1233534 ! cell fate commitment GO:0045165 118 98 0,000 0,12304908 0,12331952 ! negative regulation of cellular component organization GO:0051129 132 99 0,000 0,12422638 0,12446521 ! hormone activity GO:0005179 113 99 0,000 0,12422638 0,12443104 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,12422638 0,12439688 ! nuclear chromosome GO:0000228 127 100 0,000 0,12540217 0,12553982 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,12540217 0,12550538 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 0,000 0,12540217 0,12547096 ! regulation of lymphocyte activation GO:0051249 123 100 0,000 0,12540217 0,12543656 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,12540217 0,12540217