pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/2580-3-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein refolding GO:0042026 13 6 2,000 2,025E-08 4,805E-05 ! outer mitochondrial membrane organization GO:0007008 12 7 2,000 3,541E-08 4,202E-05 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! chaperone-mediated protein complex assembly GO:0051131 12 8 2,000 5,663E-08 4,479E-05 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 2,000 1,143E-06 6,783E-04 ! response to unfolded protein GO:0006986 113 80 3,000 1,379E-06 6,544E-04 ! response to protein stimulus GO:0051789 127 85 3,000 1,759E-06 6,958E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 2,000 2,024E-06 6,863E-04 ! mitochondrial membrane organization GO:0007006 42 25 2,000 2,299E-06 6,819E-04 ! short-chain fatty acid metabolic process GO:0046459 8 5 1,000 1,06E-05 2,795E-03 ! galactolipid metabolic process GO:0019374 8 5 1,000 1,06E-05 2,515E-03 GO:0006681|galactosylceramide metabolic process, ! mitochondrial transport GO:0006839 66 43 2,000 1,219E-05 2,629E-03 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 2,000 1,307E-05 2,584E-03 ! response to UV GO:0009411 79 47 2,000 1,597E-05 2,915E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,223E-05 3,768E-03 ! regulation of defense response to virus by virus GO:0050690 16 7 1,000 2,223E-05 3,517E-03 ! glycosylceramide metabolic process GO:0006677 10 7 1,000 2,223E-05 3,297E-03 ! mast cell activation GO:0045576 10 7 1,000 2,223E-05 3,103E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 2,000 2,297E-05 3,029E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 2,962E-05 3,699E-03 ! neurotransmitter catabolic process GO:0042135 16 8 1,000 2,962E-05 3,514E-03 ! succinate metabolic process GO:0006105 16 9 1,000 3,806E-05 4,301E-03 ! positive regulation of B cell proliferation GO:0030890 14 10 1,000 4,754E-05 5,128E-03 ! protein homotetramerization GO:0051289 20 10 1,000 4,754E-05 4,905E-03 ! thymus development GO:0048538 19 11 1,000 5,807E-05 5,742E-03 ! response to metal ion GO:0010038 114 76 2,000 6,788E-05 6,443E-03 ! T cell homeostasis GO:0043029 22 12 1,000 6,964E-05 6,356E-03 ! mitochondrion organization GO:0007005 127 78 2,000 7,335E-05 6,447E-03 ! response to inorganic substance GO:0010035 127 81 2,000 8,21E-05 6,958E-03 ! regulation of B cell proliferation GO:0030888 24 13 1,000 8,225E-05 6,73E-03 ! regulation of defense response to virus GO:0050688 26 14 1,000 9,59E-05 7,586E-03 ! glutamate metabolic process GO:0006536 21 14 1,000 9,59E-05 7,341E-03 ! interphase of mitotic cell cycle GO:0051329 166 87 2,000 1,016E-04 7,533E-03 ! interphase GO:0051325 169 89 2,000 1,087E-04 7,816E-03 ! lymphocyte homeostasis GO:0002260 29 15 1,000 1,106E-04 7,718E-03 ! cellular amino acid derivative catabolic process GO:0042219 31 16 1,000 1,263E-04 8,563E-03 ! cellular response to unfolded protein GO:0034620 24 18 1,000 1,608E-04 0,01060106 GO:0030968|endoplasmic reticulum unfolded protein response, ! aromatic compound catabolic process GO:0019439 26 18 1,000 1,608E-04 0,01031455 ! positive regulation of fibroblast proliferation GO:0048146 30 21 1,000 2,203E-04 0,01375836 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 1,000 2,203E-04 0,01340558 ! glutamine metabolic process GO:0006541 29 21 1,000 2,203E-04 0,01307044 ! neurotransmitter metabolic process GO:0042133 36 21 1,000 2,203E-04 0,01275165 ! glycosphingolipid metabolic process GO:0006687 35 21 1,000 2,203E-04 0,01244804 ! neural tube closure GO:0001843 35 22 1,000 2,422E-04 0,01336589 GO:0060606|tube closure, ! regulation of multi-organism process GO:0043900 35 22 1,000 2,422E-04 0,01306212 ! protein tetramerization GO:0051262 43 22 1,000 2,422E-04 0,01277185 ! dicarboxylic acid metabolic process GO:0043648 36 23 1,000 2,651E-04 0,01367542 ! tube lumen formation GO:0035148 37 23 1,000 2,651E-04 0,01338445 ! glycolipid metabolic process GO:0006664 39 23 1,000 2,651E-04 0,01310561 ! cellular response to extracellular stimulus GO:0031668 37 23 1,000 2,651E-04 0,01283815 ! positive regulation of B cell activation GO:0050871 36 23 1,000 2,651E-04 0,01258139 ! response to endoplasmic reticulum stress GO:0034976 32 24 1,000 2,89E-04 0,01344747 ! primary neural tube formation GO:0014020 37 24 1,000 2,89E-04 0,01318886 ! regulation of response to biotic stimulus GO:0002831 45 24 1,000 2,89E-04 0,01294001 ! regulation of fibroblast proliferation GO:0048145 39 25 1,000 3,139E-04 0,01379598 ! negative regulation of phosphorylation GO:0042326 46 25 1,000 3,139E-04 0,01354514 ! leukocyte homeostasis GO:0001776 40 25 1,000 3,139E-04 0,01330327 ! ER-nuclear signaling pathway GO:0006984 33 26 1,000 3,399E-04 0,01415002 ! fat cell differentiation GO:0045444 41 27 1,000 3,668E-04 0,01500898 ! negative regulation of phosphorus metabolic process GO:0010563 51 27 1,000 3,668E-04 0,0147546 GO:0045936|negative regulation of phosphate metabolic process, ! glutathione metabolic process GO:0006749 35 27 1,000 3,668E-04 0,01450869 ! myeloid leukocyte activation GO:0002274 44 29 1,000 4,238E-04 0,01648601 ! neural tube formation GO:0001841 46 29 1,000 4,238E-04 0,01622011 ! ceramide metabolic process GO:0006672 47 30 1,000 4,538E-04 0,01709195 ! fatty acid catabolic process GO:0009062 45 30 1,000 4,538E-04 0,01682489 ! post-embryonic development GO:0009791 50 31 1,000 4,848E-04 0,01769726 ! embryonic epithelial tube formation GO:0001838 50 31 1,000 4,848E-04 0,01742912 ! sphingoid metabolic process GO:0046519 51 33 1,000 5,497E-04 0,01947031 ! regulation of B cell activation GO:0050864 55 33 1,000 5,497E-04 0,01918398 ! protein homooligomerization GO:0051260 59 35 1,000 6,187E-04 0,02127791 ! neural tube development GO:0021915 58 39 1,000 7,686E-04 0,0260541 ! positive regulation of leukocyte proliferation GO:0070665 64 39 1,000 7,686E-04 0,02568714 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! morphogenesis of embryonic epithelium GO:0016331 69 42 1,000 8,913E-04 0,02937634 ! induction of apoptosis by intracellular signals GO:0008629 78 42 1,000 8,913E-04 0,02897392 ! response to calcium ion GO:0051592 65 43 1,000 9,342E-04 0,02995759 ! peptide metabolic process GO:0006518 64 44 1,000 9,781E-04 0,03094599 ! positive regulation of cell cycle GO:0045787 83 45 1,000 1,023E-03 0,0319389 ! epithelial tube morphogenesis GO:0060562 73 46 1,000 1,069E-03 0,03293607 ! respiratory electron transport chain GO:0022904 63 49 1,000 1,212E-03 0,03687281 ! regulation of mast cell proliferation GO:0070666 80 50 1,000 1,262E-03 0,03789888 ! glutamine family amino acid metabolic process GO:0009064 71 53 1,000 1,417E-03 0,04201924 ! regulation of leukocyte proliferation GO:0070663 88 53 1,000 1,417E-03 0,04150048 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! sphingolipid metabolic process GO:0006665 80 54 1,000 1,47E-03 0,04254403 ! regulation of neurotransmitter levels GO:0001505 85 57 1,000 1,637E-03 0,04678852 ! membrane lipid metabolic process GO:0006643 88 58 1,000 1,694E-03 0,04785222 ! negative regulation of protein kinase activity GO:0006469 110 62 1,000 1,933E-03 0,05396062 ! negative regulation of kinase activity GO:0033673 112 63 1,000 1,995E-03 0,0550468 ! negative regulation of cell growth GO:0030308 123 65 1,000 2,122E-03 0,05787892 ! negative regulation of transferase activity GO:0051348 117 66 1,000 2,187E-03 0,05897188 ! protein oligomerization GO:0051259 109 66 1,000 2,187E-03 0,05830928 ! negative regulation of cell size GO:0045792 125 67 1,000 2,253E-03 0,05939784 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 2,32E-03 0,06048682 ! homeostasis of number of cells GO:0048872 109 72 1,000 2,596E-03 0,06696036 ! regulation of immune effector process GO:0002697 121 72 1,000 2,596E-03 0,06624036 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 2,813E-03 0,07101535 ! cellular lipid catabolic process GO:0044242 117 77 1,000 2,962E-03 0,07399735 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 2,962E-03 0,07322654 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of growth GO:0045926 140 78 1,000 3,038E-03 0,07433155 ! tube morphogenesis GO:0035239 140 80 1,000 3,193E-03 0,07732127 ! protein ubiquitination GO:0016567 135 80 1,000 3,193E-03 0,07654025 ! positive regulation of protein modification process GO:0031401 126 83 1,000 3,432E-03 0,08144653 ! positive regulation of lymphocyte activation GO:0051251 134 83 1,000 3,432E-03 0,08064013 ! cellular respiration GO:0045333 119 85 1,000 3,596E-03 0,08366179 ! regulation of defense response GO:0031347 135 87 1,000 3,764E-03 0,0867078 ! positive regulation of cell activation GO:0050867 146 90 1,000 4,021E-03 0,09175923 GO:0002696|positive regulation of leukocyte activation, ! carboxylic acid catabolic process GO:0046395 132 91 1,000 4,109E-03 0,09286873 GO:0016054|organic acid catabolic process, ! cell cycle arrest GO:0007050 171 93 1,000 4,287E-03 0,09598172 ! protein modification by small protein conjugation GO:0032446 153 96 1,000 4,561E-03 0,10115976 ! electron transport chain GO:0022900 135 99 1,000 4,843E-03 0,10641613 ! glycerophospholipid metabolic process GO:0006650 143 99 1,000 4,843E-03 0,10543984 ! sulfur metabolic process GO:0006790 136 99 1,000 4,843E-03 0,10448129 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 5,269E-03 0,11264175 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 5,269E-03 0,11163602 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 5,269E-03 0,11064809 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 5,269E-03 0,10967749 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 5,269E-03 0,10872377 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 5,269E-03 0,1077865 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,269E-03 0,10686525 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 5,269E-03 0,10595961 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 5,269E-03 0,10506919 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 5,269E-03 0,10419362 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 5,269E-03 0,10333251 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 5,269E-03 0,10248552 ! response to oxygen radical GO:0000305 11 5 0,000 5,269E-03 0,10165231 ! negative regulation of bone resorption GO:0045779 11 5 0,000 5,269E-03 0,10083253 ! myoblast cell fate commitment GO:0048625 8 5 0,000 5,269E-03 0,10002587 ! nucleotide-sugar transport GO:0015780 8 5 0,000 5,269E-03 0,09923202 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 5,269E-03 0,09845066 ! regulation of interferon-beta production GO:0032648 5 5 0,000 5,269E-03 0,09768152 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 5,269E-03 0,09692429 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 5,269E-03 0,09617872 ! female meiosis GO:0007143 8 5 0,000 5,269E-03 0,09544453 ! nose development GO:0043584 10 5 0,000 5,269E-03 0,09472147 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 5,269E-03 0,09400928 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 5,269E-03 0,09330772 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 5,269E-03 0,09261655 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 5,269E-03 0,09193554 ! cobalt ion transport GO:0006824 9 5 0,000 5,269E-03 0,09126448 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 5,269E-03 0,09060314 ! SMAD protein complex assembly GO:0007183 10 5 0,000 5,269E-03 0,08995132 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 5,269E-03 0,08930881 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 5,269E-03 0,08867542 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 5,269E-03 0,08805094 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 5,269E-03 0,0874352 ! adaptation of signaling pathway GO:0022401 9 5 0,000 5,269E-03 0,08682801 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 5,269E-03 0,0862292 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 5,269E-03 0,08563859 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 5,269E-03 0,08505601 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 5,269E-03 0,08448131 ! negative regulation of histone modification GO:0031057 7 5 0,000 5,269E-03 0,08391432 ! malate metabolic process GO:0006108 8 5 0,000 5,269E-03 0,08335489 ! positive regulation of histone modification GO:0031058 6 5 0,000 5,269E-03 0,08280287 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 5,269E-03 0,08225812 ! clathrin coat assembly GO:0048268 11 5 0,000 5,269E-03 0,08172048 ! Notch receptor processing GO:0007220 8 5 0,000 5,269E-03 0,08118983 ! phototransduction, visible light GO:0007603 7 5 0,000 5,269E-03 0,08066603 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,269E-03 0,08014894 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 5,269E-03 0,07963843 ! mating behavior GO:0007617 6 5 0,000 5,269E-03 0,07913439 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 5,269E-03 0,07863669 ! copulation GO:0007620 8 5 0,000 5,269E-03 0,07814521 ! protein maturation by protein folding GO:0022417 13 5 0,000 5,269E-03 0,07765984 ! embryonic hemopoiesis GO:0035162 13 5 0,000 5,269E-03 0,07718046 ! regulation of potassium ion transport GO:0043266 9 5 0,000 5,269E-03 0,07670696 ! apoptotic cell clearance GO:0043277 14 5 0,000 5,269E-03 0,07623923 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 5,269E-03 0,07577718 ! lipoprotein particle clearance GO:0034381 9 5 0,000 5,269E-03 0,07532069 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 5,269E-03 0,07486966 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 5,269E-03 0,07442401 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 5,269E-03 0,07398363 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 5,269E-03 0,07354844 ! response to axon injury GO:0048678 8 5 0,000 5,269E-03 0,07311833 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,269E-03 0,07269322 ! response to protozoan GO:0001562 10 5 0,000 5,269E-03 0,07227303 ! negative regulation of heart contraction GO:0045822 12 5 0,000 5,269E-03 0,07185767 ! lymph vessel development GO:0001945 8 5 0,000 5,269E-03 0,07144705 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 5,269E-03 0,0710411 ! endochondral ossification GO:0001958 13 5 0,000 5,269E-03 0,07063974 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 5,269E-03 0,07024289 ! single strand break repair GO:0000012 5 5 0,000 5,269E-03 0,06985047 ! parathyroid gland development GO:0060017 8 5 0,000 5,269E-03 0,06946241 ! anagen GO:0042640 7 5 0,000 5,269E-03 0,06907864 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 5,269E-03 0,06869909 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 5,269E-03 0,06832368 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 5,269E-03 0,06795236 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 5,269E-03 0,06758505 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 5,269E-03 0,06722169 ! smooth muscle tissue development GO:0048745 14 5 0,000 5,269E-03 0,06686221 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,269E-03 0,06650656 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 5,269E-03 0,06615468 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 5,269E-03 0,06580649 ! cardiac muscle fiber development GO:0048739 8 5 0,000 5,269E-03 0,06546196 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,269E-03 0,06512101 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 5,269E-03 0,0647836 ! neutrophil mediated immunity GO:0002446 6 5 0,000 5,269E-03 0,06444966 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,269E-03 0,06411915 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 5,269E-03 0,06379201 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 5,269E-03 0,06346819 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 5,269E-03 0,06314765 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 5,269E-03 0,06283032 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 5,269E-03 0,06251617 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 5,269E-03 0,06220514 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 5,269E-03 0,0618972 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 5,269E-03 0,06159229 ! tyrosine catabolic process GO:0006572 7 5 0,000 5,269E-03 0,06129036 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 5,269E-03 0,06099139 ! proline biosynthetic process GO:0006561 6 5 0,000 5,269E-03 0,06069531 ! L-serine biosynthetic process GO:0006564 6 5 0,000 5,269E-03 0,0604021 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 5,269E-03 0,0601117 ! polyol catabolic process GO:0046174 7 5 0,000 5,269E-03 0,05982409 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 5,269E-03 0,05953921 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 5,269E-03 0,05925703 ! sister chromatid cohesion GO:0007062 10 5 0,000 5,269E-03 0,05897752 ! response to ATP GO:0033198 6 5 0,000 5,269E-03 0,05870063 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 5,269E-03 0,05842633 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 5,269E-03 0,05815458 ! neutrophil activation GO:0042119 6 5 0,000 5,269E-03 0,05788534 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 5,269E-03 0,05761859 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 5,269E-03 0,05735428 ! response to food GO:0032094 5 5 0,000 5,269E-03 0,05709239 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 5,269E-03 0,05683288 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 5,269E-03 0,05657572 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 5,269E-03 0,05632087 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,269E-03 0,05606831 ! paraxial mesoderm development GO:0048339 9 5 0,000 5,269E-03 0,05581801 ! forebrain neuron development GO:0021884 7 5 0,000 5,269E-03 0,05556993 ! melanosome organization GO:0032438 7 5 0,000 5,269E-03 0,05532404 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 5,269E-03 0,05508033 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 5,269E-03 0,05483875 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,269E-03 0,05459927 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 5,269E-03 0,05436189 ! mesodermal cell fate determination GO:0007500 7 5 0,000 5,269E-03 0,05412655 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,269E-03 0,05389325 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 5,269E-03 0,05366195 ! nucleoside salvage GO:0043174 7 5 0,000 5,269E-03 0,05343262 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 5,269E-03 0,05320525 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 5,269E-03 0,0529798 ! negative regulation of platelet activation GO:0010544 8 5 0,000 5,269E-03 0,05275626 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 5,269E-03 0,0525346 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 5,269E-03 0,05231479 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 5,269E-03 0,05209681 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 5,269E-03 0,05188064 ! early endosome to late endosome transport GO:0045022 11 5 0,000 5,269E-03 0,05166626 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 5,269E-03 0,05145364 ! depyrimidination GO:0045008 8 5 0,000 5,269E-03 0,05124276 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,269E-03 0,05103361 ! 5S class rRNA transcription GO:0042791 8 5 0,000 5,269E-03 0,05082615 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 5,269E-03 0,05062038 ! neuronal ion channel clustering GO:0045161 8 5 0,000 5,269E-03 0,05041627 ! sodium ion homeostasis GO:0055078 6 5 0,000 5,269E-03 0,05021379 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 5,269E-03 0,05001294 ! monocyte differentiation GO:0030224 7 5 0,000 5,269E-03 0,04981368 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 5,269E-03 0,04961601 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 5,269E-03 0,0494199 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 5,269E-03 0,04922533 ! response to UV-C GO:0010225 7 5 0,000 5,269E-03 0,04903229 ! protein targeting to vacuole GO:0006623 6 5 0,000 5,269E-03 0,04884076 ! activated T cell proliferation GO:0050798 7 5 0,000 5,269E-03 0,04865072 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 5,269E-03 0,04846215 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 5,269E-03 0,04827503 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 5,269E-03 0,04808936 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 5,269E-03 0,04790511 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 5,269E-03 0,04772227 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 5,269E-03 0,04754081 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 5,269E-03 0,04736073 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 5,269E-03 0,04718201 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 5,269E-03 0,04700464 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 5,269E-03 0,04682859 ! response to cadmium ion GO:0046686 8 5 0,000 5,269E-03 0,04665386 ! melanosome transport GO:0032402 8 5 0,000 5,269E-03 0,04648042 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,269E-03 0,04630827 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 5,269E-03 0,04613739 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 5,269E-03 0,04596777 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 5,269E-03 0,04579939 ! positive T cell selection GO:0043368 10 5 0,000 5,269E-03 0,04563224 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 5,269E-03 0,04546631 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 5,269E-03 0,04530157 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 5,269E-03 0,04513803 ! ribosomal subunit assembly GO:0042257 5 5 0,000 5,269E-03 0,04497566 ! base conversion or substitution editing GO:0016553 6 5 0,000 5,269E-03 0,04481446 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 5,269E-03 0,04465441 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 5,269E-03 0,04449549 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 5,269E-03 0,04433771 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 5,269E-03 0,04418104 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 5,269E-03 0,04402547 ! histone demethylation GO:0016577 10 5 0,000 5,269E-03 0,043871 ! mitotic recombination GO:0006312 10 5 0,000 5,269E-03 0,0437176 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 5,269E-03 0,04356528 ! regulation of sterol transport GO:0032371 7 5 0,000 5,269E-03 0,04341401 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 5,269E-03 0,04326379 ! sympathetic nervous system development GO:0048485 13 5 0,000 5,269E-03 0,0431146 ! enteric nervous system development GO:0048484 9 5 0,000 5,269E-03 0,04296644 ! oxygen homeostasis GO:0032364 8 5 0,000 5,269E-03 0,04281929 ! establishment of planar polarity GO:0001736 7 5 0,000 5,269E-03 0,04267315 ! lymphocyte costimulation GO:0031294 12 5 0,000 5,269E-03 0,04252801 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 5,269E-03 0,04238384 ! transcription termination GO:0006353 8 5 0,000 5,269E-03 0,04224066 ! plasminogen activation GO:0031639 5 5 0,000 5,269E-03 0,04209843 ! B cell homeostasis GO:0001782 12 5 0,000 5,269E-03 0,04195716 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 5,269E-03 0,04181684 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 5,269E-03 0,04167745 ! regulation of hair follicle development GO:0051797 9 5 0,000 5,269E-03 0,04153898 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 5,269E-03 0,04140144 ! apical protein localization GO:0045176 8 5 0,000 5,269E-03 0,0412648 ! definitive hemopoiesis GO:0060216 5 5 0,000 5,269E-03 0,04112906 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 5,269E-03 0,04099421 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 5,269E-03 0,04086024 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 5,269E-03 0,04072715 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 5,269E-03 0,04059492 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 5,269E-03 0,04046354 ! regulation of centrosome duplication GO:0010824 6 5 0,000 5,269E-03 0,04033301 ! disaccharide metabolic process GO:0005984 9 5 0,000 5,269E-03 0,04020332 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,269E-03 0,04007447 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 5,269E-03 0,03994643 ! determination of adult lifespan GO:0008340 8 5 0,000 5,269E-03 0,03981922 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 5,269E-03 0,03969281 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 5,269E-03 0,0395672 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 5,269E-03 0,03944238 ! T cell activation during immune response GO:0002286 9 5 0,000 5,269E-03 0,03931835 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 5,269E-03 0,03919509 ! negative regulation of lipase activity GO:0060192 7 5 0,000 5,269E-03 0,03907261 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 5,269E-03 0,03895088 ! neural plate development GO:0001840 7 5 0,000 5,269E-03 0,03882992 ! regulation of sensory perception GO:0051931 6 5 0,000 5,269E-03 0,0387097 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 5,269E-03 0,03859023 ! regulation of histone acetylation GO:0035065 7 5 0,000 5,269E-03 0,03847149 ! sensory cilium assembly GO:0035058 6 5 0,000 5,269E-03 0,03835348 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 5,269E-03 0,03823619 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 5,269E-03 0,03811962 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 5,269E-03 0,03800375 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 5,269E-03 0,03788859 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 5,269E-03 0,03777412 ! receptor biosynthetic process GO:0032800 6 5 0,000 5,269E-03 0,03766034 ! penetration of zona pellucida GO:0007341 9 5 0,000 5,269E-03 0,03754725 ! drug metabolic process GO:0017144 5 5 0,000 5,269E-03 0,03743483 ! protein amino acid prenylation GO:0018346 9 5 0,000 5,269E-03 0,03732309 ! organ regeneration GO:0031100 7 5 0,000 5,269E-03 0,03721201 ! carnitine metabolic process GO:0009437 5 5 0,000 5,269E-03 0,03710158 GO:0006577|betaine metabolic process, ! tRNA transcription GO:0009304 11 6 0,000 6,32E-03 0,04436787 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 6,32E-03 0,04423699 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 6,32E-03 0,04410688 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 6,32E-03 0,04397754 ! regulation of helicase activity GO:0051095 11 6 0,000 6,32E-03 0,04384895 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 6,32E-03 0,04372111 ! sleep GO:0030431 13 6 0,000 6,32E-03 0,04359401 ! positive regulation of axon extension GO:0045773 10 6 0,000 6,32E-03 0,04346765 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 6,32E-03 0,04334202 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 6,32E-03 0,04321712 ! forebrain regionalization GO:0021871 7 6 0,000 6,32E-03 0,04309293 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 6,32E-03 0,04296946 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 6,32E-03 0,04284669 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 6,32E-03 0,04272462 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 6,32E-03 0,04260324 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 6,32E-03 0,04248255 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 6,32E-03 0,04236254 ! neuron adhesion GO:0007158 9 6 0,000 6,32E-03 0,04224321 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 6,32E-03 0,04212455 ! signal peptide processing GO:0006465 8 6 0,000 6,32E-03 0,04200656 ! embryonic camera-type eye development GO:0031076 11 6 0,000 6,32E-03 0,04188922 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 6,32E-03 0,04177254 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 6,32E-03 0,0416565 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 6,32E-03 0,04154111 ! fibril organization GO:0043206 13 6 0,000 6,32E-03 0,04142635 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 6,32E-03 0,04131223 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 6,32E-03 0,04119874 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 6,32E-03 0,04108586 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 6,32E-03 0,04097361 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 6,32E-03 0,04086196 ! rhythmic behavior GO:0007622 14 6 0,000 6,32E-03 0,04075092 ! glial cell fate commitment GO:0021781 17 6 0,000 6,32E-03 0,04064049 ! erythrocyte maturation GO:0043249 7 6 0,000 6,32E-03 0,04053065 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 6,32E-03 0,0404214 ! protein amino acid dealkylation GO:0008214 12 6 0,000 6,32E-03 0,04031274 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 6,32E-03 0,04020467 ! regulation of odontogenesis GO:0042481 8 6 0,000 6,32E-03 0,04009717 ! mechanosensory behavior GO:0007638 8 6 0,000 6,32E-03 0,03999024 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 6,32E-03 0,03988388 ! negative regulation of endocytosis GO:0045806 8 6 0,000 6,32E-03 0,03977809 ! response to interferon-gamma GO:0034341 12 6 0,000 6,32E-03 0,03967286 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 6,32E-03 0,03956818 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 6,32E-03 0,03946405 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 6,32E-03 0,03936047 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 6,32E-03 0,03925744 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 6,32E-03 0,03915494 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 6,32E-03 0,03905297 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 6,32E-03 0,03895153 ! cGMP-mediated signaling GO:0019934 11 6 0,000 6,32E-03 0,03885062 ! activation of MAPKKK activity GO:0000185 11 6 0,000 6,32E-03 0,03875023 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 6,32E-03 0,03865036 ! protein lipoylation GO:0009249 10 6 0,000 6,32E-03 0,038551 ! pigment granule organization GO:0048753 11 6 0,000 6,32E-03 0,03845215 ! drug transport GO:0015893 6 6 0,000 6,32E-03 0,03835381 ! transepithelial chloride transport GO:0030321 10 6 0,000 6,32E-03 0,03825597 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 6,32E-03 0,03815863 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 6,32E-03 0,03806178 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 6,32E-03 0,03796542 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 6,32E-03 0,03786955 ! glutamate catabolic process GO:0006538 11 6 0,000 6,32E-03 0,03777416 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 6,32E-03 0,03767925 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 6,32E-03 0,03758481 ! adenohypophysis development GO:0021984 10 6 0,000 6,32E-03 0,03749085 ! response to pH GO:0009268 10 6 0,000 6,32E-03 0,03739736 ! hyperosmotic response GO:0006972 9 6 0,000 6,32E-03 0,03730433 ! microtubule nucleation GO:0007020 10 6 0,000 6,32E-03 0,03721176 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 6,32E-03 0,03711965 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 6,32E-03 0,037028 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 6,32E-03 0,0369368 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 6,32E-03 0,03684604 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 6,32E-03 0,03675574 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 6,32E-03 0,03666587 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 6,32E-03 0,03657644 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 6,32E-03 0,03648745 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 6,32E-03 0,03639888 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 6,32E-03 0,03631075 ! purine salvage GO:0043101 9 6 0,000 6,32E-03 0,03622304 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 6,32E-03 0,03613576 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 6,32E-03 0,03604889 ! nucleoside transport GO:0015858 7 6 0,000 6,32E-03 0,03596245 ! organic alcohol transport GO:0015850 9 6 0,000 6,32E-03 0,03587641 ! T cell mediated immunity GO:0002456 12 6 0,000 6,32E-03 0,03579079 ! folic acid transport GO:0015884 11 6 0,000 6,32E-03 0,03570557 ! male sex determination GO:0030238 11 6 0,000 6,32E-03 0,03562076 ! carnitine transport GO:0015879 8 6 0,000 6,32E-03 0,03553635 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 6,32E-03 0,03545234 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,32E-03 0,03536873 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 6,32E-03 0,03528551 ! positive regulation of exocytosis GO:0045921 9 6 0,000 6,32E-03 0,03520268 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 6,32E-03 0,03512023 ! parturition GO:0007567 13 6 0,000 6,32E-03 0,03503818 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 6,32E-03 0,0349565 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 6,32E-03 0,03487521 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 6,32E-03 0,03479429 ! regulation of centrosome cycle GO:0046605 8 6 0,000 6,32E-03 0,03471375 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 6,32E-03 0,03463358 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 6,32E-03 0,03455378 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 6,32E-03 0,03447435 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 6,32E-03 0,03439528 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 6,32E-03 0,03431657 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 6,32E-03 0,03423822 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 6,32E-03 0,03416023 ! neural nucleus development GO:0048857 12 6 0,000 6,32E-03 0,03408259 ! forebrain morphogenesis GO:0048853 14 6 0,000 6,32E-03 0,03400531 ! hyaluronan metabolic process GO:0030212 7 6 0,000 6,32E-03 0,03392837 ! purine base biosynthetic process GO:0009113 14 6 0,000 6,32E-03 0,03385178 ! interaction with symbiont GO:0051702 9 6 0,000 6,32E-03 0,03377554 ! regulation of dendrite development GO:0050773 13 6 0,000 6,32E-03 0,03369964 ! anterograde axon cargo transport GO:0008089 9 6 0,000 6,32E-03 0,03362408 ! positive regulation of organ growth GO:0046622 7 6 0,000 6,32E-03 0,03354886 ! eating behavior GO:0042755 6 6 0,000 6,32E-03 0,03347397 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 6,32E-03 0,03339942 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 6,32E-03 0,0333252 ! response to copper ion GO:0046688 9 6 0,000 6,32E-03 0,03325131 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 6,32E-03 0,03317774 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 6,32E-03 0,0331045 ! establishment of melanosome localization GO:0032401 9 6 0,000 6,32E-03 0,03303159 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,32E-03 0,03295899 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 6,32E-03 0,03288671 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 6,32E-03 0,03281475 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,32E-03 0,0327431 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,32E-03 0,03267177 ! hair follicle maturation GO:0048820 8 6 0,000 6,32E-03 0,03260074 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 6,32E-03 0,03253002 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 6,32E-03 0,03245961 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 6,32E-03 0,0323895 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 6,32E-03 0,0323197 ! rhombomere development GO:0021546 6 6 0,000 6,32E-03 0,03225019 ! positive regulation of Rho GTPase activity GO:0032321 12 6 0,000 6,32E-03 0,03218099 ! G2 phase GO:0051319 15 6 0,000 6,32E-03 0,03211208 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 6,32E-03 0,03204346 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 6,32E-03 0,03197514 ! muscle cell proliferation GO:0033002 9 6 0,000 6,32E-03 0,03190711 ! membrane to membrane docking GO:0022614 12 6 0,000 6,32E-03 0,03183936 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 6,32E-03 0,03177191 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 6,32E-03 0,03170474 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 6,32E-03 0,03163785 ! receptor internalization GO:0031623 9 6 0,000 6,32E-03 0,03157124 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 6,32E-03 0,03150492 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 6,32E-03 0,03143887 ! coenzyme A metabolic process GO:0015936 9 6 0,000 6,32E-03 0,0313731 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 6,32E-03 0,0313076 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 6,32E-03 0,03124238 ! peptidyl-histidine modification GO:0018202 10 6 0,000 6,32E-03 0,03117742 ! axonal fasciculation GO:0007413 10 6 0,000 6,32E-03 0,03111274 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 6,32E-03 0,03104832 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 6,32E-03 0,03098417 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 6,32E-03 0,03092029 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 6,32E-03 0,03085667 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 6,32E-03 0,03079331 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 6,32E-03 0,03073021 ! progesterone metabolic process GO:0042448 8 6 0,000 6,32E-03 0,03066736 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 6,32E-03 0,03060478 ! glycolipid catabolic process GO:0019377 14 6 0,000 6,32E-03 0,03054244 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 6,32E-03 0,03048037 ! negative regulation of axon extension GO:0030517 13 6 0,000 6,32E-03 0,03041854 ! removal of superoxide radicals GO:0019430 10 6 0,000 6,32E-03 0,03035696 ! triglyceride catabolic process GO:0019433 8 6 0,000 6,32E-03 0,03029564 ! protein modification by small protein removal GO:0070646 10 6 0,000 6,32E-03 0,03023456 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 6,32E-03 0,03017372 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 6,32E-03 0,03011313 ! glial cell migration GO:0008347 11 6 0,000 6,32E-03 0,03005279 ! blastocyst growth GO:0001832 17 6 0,000 6,32E-03 0,02999268 ! pigment granule transport GO:0051904 12 6 0,000 6,32E-03 0,02993281 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 6,32E-03 0,02987319 ! cerebellar cortex formation GO:0021697 9 6 0,000 6,32E-03 0,0298138 ! catecholamine transport GO:0051937 7 6 0,000 6,32E-03 0,02975464 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 6,32E-03 0,02969572 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 6,32E-03 0,02963704 ! organ or tissue specific immune response GO:0002251 7 6 0,000 6,32E-03 0,02957858 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 6,32E-03 0,02952035 ! spindle assembly GO:0051225 6 6 0,000 6,32E-03 0,02946236 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 6,32E-03 0,02940459 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 6,32E-03 0,02934705 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 6,32E-03 0,02928973 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 6,32E-03 0,02923263 ! NAD biosynthetic process GO:0009435 9 6 0,000 6,32E-03 0,02917576 ! positive regulation of coagulation GO:0050820 11 6 0,000 6,32E-03 0,02911911 ! cellular anion homeostasis GO:0030002 9 6 0,000 6,32E-03 0,02906267 GO:0055081|anion homeostasis, ! behavioral response to cocaine GO:0048148 13 7 0,000 7,369E-03 0,03382387 ! autophagic vacuole formation GO:0000045 12 7 0,000 7,369E-03 0,03375857 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 7,369E-03 0,03369352 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 7,369E-03 0,03362873 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 7,369E-03 0,03356418 ! prostate gland development GO:0030850 11 7 0,000 7,369E-03 0,03349988 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 7,369E-03 0,03343583 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 7,369E-03 0,03337202 ! synaptonemal complex assembly GO:0007130 11 7 0,000 7,369E-03 0,03330845 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 7,369E-03 0,03324513 ! male meiosis GO:0007140 10 7 0,000 7,369E-03 0,03318205 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,369E-03 0,0331192 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 7,369E-03 0,03305659 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 7,369E-03 0,03299422 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 7,369E-03 0,03293209 ! oligopeptide transport GO:0006857 11 7 0,000 7,369E-03 0,03287019 ! protein amino acid sulfation GO:0006477 9 7 0,000 7,369E-03 0,03280852 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 7,369E-03 0,03274708 ! establishment of tissue polarity GO:0007164 10 7 0,000 7,369E-03 0,03268587 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 7,369E-03 0,03262489 ! RNA methylation GO:0001510 11 7 0,000 7,369E-03 0,03256413 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 7,369E-03 0,0325036 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 7,369E-03 0,0324433 ! pericardium development GO:0060039 9 7 0,000 7,369E-03 0,03238322 ! macrophage chemotaxis GO:0048246 10 7 0,000 7,369E-03 0,03232336 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 7,369E-03 0,03226372 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 7,369E-03 0,03220431 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 7,369E-03 0,03214511 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 7,369E-03 0,03208613 ! cerebral cortex cell migration GO:0021795 11 7 0,000 7,369E-03 0,03202736 ! opsonization GO:0008228 9 7 0,000 7,369E-03 0,03196881 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 7,369E-03 0,03191047 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 7,369E-03 0,03185235 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 7,369E-03 0,03179443 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 7,369E-03 0,03173673 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 7,369E-03 0,03167924 ! chemosensory behavior GO:0007635 9 7 0,000 7,369E-03 0,03162195 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 7,369E-03 0,03156487 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 7,369E-03 0,031508 ! leukocyte degranulation GO:0043299 11 7 0,000 7,369E-03 0,03145133 ! positive regulation of glycolysis GO:0045821 13 7 0,000 7,369E-03 0,03139486 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 7,369E-03 0,0313386 ! positive regulation of heart rate GO:0010460 11 7 0,000 7,369E-03 0,03128254 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,369E-03 0,03122668 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 7,369E-03 0,03117101 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 7,369E-03 0,03111555 ! spinal cord patterning GO:0021511 9 7 0,000 7,369E-03 0,03106028 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 7,369E-03 0,03100521 ! thymic T cell selection GO:0045061 15 7 0,000 7,369E-03 0,03095033 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 7,369E-03 0,03089565 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 7,369E-03 0,03084116 ! ovulation GO:0030728 8 7 0,000 7,369E-03 0,03078686 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 7,369E-03 0,03073276 ! histidine metabolic process GO:0006547 7 7 0,000 7,369E-03 0,03067884 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 7,369E-03 0,03062511 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 7,369E-03 0,03057157 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 7,369E-03 0,03051822 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 7,369E-03 0,03046505 ! thyroid hormone generation GO:0006590 11 7 0,000 7,369E-03 0,03041207 ! endosome organization GO:0007032 10 7 0,000 7,369E-03 0,03035927 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 7,369E-03 0,03030665 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 7,369E-03 0,03025422 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 7,369E-03 0,03020197 ! urea metabolic process GO:0019627 9 7 0,000 7,369E-03 0,03014989 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 7,369E-03 0,030098 ! vesicle fusion GO:0006906 15 7 0,000 7,369E-03 0,03004629 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 7,369E-03 0,02999475 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 7,369E-03 0,02994339 ! intracellular pH reduction GO:0051452 11 7 0,000 7,369E-03 0,0298922 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 7,369E-03 0,02984119 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 7,369E-03 0,02979036 ! organ growth GO:0035265 13 7 0,000 7,369E-03 0,02973969 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 7,369E-03 0,0296892 ! Rac protein signal transduction GO:0016601 7 7 0,000 7,369E-03 0,02963888 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 7,369E-03 0,02958873 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 7,369E-03 0,02953875 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 7,369E-03 0,02948894 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 7,369E-03 0,02943929 ! rRNA modification GO:0000154 12 7 0,000 7,369E-03 0,02938981 ! negative regulation of translational initiation GO:0045947 9 7 0,000 7,369E-03 0,0293405 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 7,369E-03 0,02929135 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 7,369E-03 0,02924237 ! protein heterooligomerization GO:0051291 10 7 0,000 7,369E-03 0,02919355 ! response to UV-B GO:0010224 11 7 0,000 7,369E-03 0,0291449 ! astrocyte development GO:0014002 15 7 0,000 7,369E-03 0,0290964 ! intermediate filament organization GO:0045109 12 7 0,000 7,369E-03 0,02904807 ! cardiac muscle cell development GO:0055013 9 7 0,000 7,369E-03 0,0289999 ! fibrinolysis GO:0042730 9 7 0,000 7,369E-03 0,02895189 ! peptidyl-arginine modification GO:0018195 9 7 0,000 7,369E-03 0,02890403 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 7,369E-03 0,02885633 ! blastoderm segmentation GO:0007350 11 7 0,000 7,369E-03 0,0288088 ! skeletal muscle contraction GO:0003009 8 7 0,000 7,369E-03 0,02876141 ! B cell lineage commitment GO:0002326 17 7 0,000 7,369E-03 0,02871418 ! DNA topological change GO:0006265 10 7 0,000 7,369E-03 0,02866711 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 7,369E-03 0,02862019 ! melanosome localization GO:0032400 10 7 0,000 7,369E-03 0,02857343 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 7,369E-03 0,02852682 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 7,369E-03 0,02848036 ! multicellular organismal aging GO:0010259 11 7 0,000 7,369E-03 0,02843405 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 7,369E-03 0,02838789 ! gas homeostasis GO:0033483 12 7 0,000 7,369E-03 0,02834188 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 7,369E-03 0,02829602 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 7,369E-03 0,0282503 ! Schwann cell development GO:0014044 16 7 0,000 7,369E-03 0,02820474 ! dendrite morphogenesis GO:0048813 12 7 0,000 7,369E-03 0,02815932 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 7,369E-03 0,02811405 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 7,369E-03 0,02806892 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 7,369E-03 0,02802394 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 7,369E-03 0,0279791 ! neural tube patterning GO:0021532 8 7 0,000 7,369E-03 0,02793441 ! histone ubiquitination GO:0016574 10 7 0,000 7,369E-03 0,02788985 ! regulation of meiosis GO:0040020 12 7 0,000 7,369E-03 0,02784544 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 7,369E-03 0,02780117 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 7,369E-03 0,02775705 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 7,369E-03 0,02771306 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 7,369E-03 0,02766921 ! regulation of lipid transport GO:0032368 13 7 0,000 7,369E-03 0,0276255 ! regulation of cell division GO:0051302 9 7 0,000 7,369E-03 0,02758192 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 7,369E-03 0,02753849 ! neutrophil homeostasis GO:0001780 8 7 0,000 7,369E-03 0,02749519 ! regulation of macrophage activation GO:0043030 12 7 0,000 7,369E-03 0,02745202 ! negative regulation of nuclear division GO:0051784 18 7 0,000 7,369E-03 0,02740899 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 7,369E-03 0,0273661 ! diuresis GO:0030146 11 7 0,000 7,369E-03 0,02732334 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 7,369E-03 0,02728072 ! positive regulation of epidermis development GO:0045684 11 7 0,000 7,369E-03 0,02723822 ! thiamin metabolic process GO:0006772 8 7 0,000 7,369E-03 0,02719586 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 7,369E-03 0,02715363 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 7,369E-03 0,02711153 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 7,369E-03 0,02706956 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 7,369E-03 0,02702773 ! dopamine biosynthetic process GO:0042416 15 7 0,000 7,369E-03 0,02698602 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 7,369E-03 0,02694444 ! lymph node development GO:0048535 9 7 0,000 7,369E-03 0,02690298 ! anterior/posterior axis specification GO:0009948 11 7 0,000 7,369E-03 0,02686166 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 7,369E-03 0,02682046 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 7,369E-03 0,02677939 ! positive regulation of glucose import GO:0046326 7 7 0,000 7,369E-03 0,02673844 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 7,369E-03 0,02669762 ! ATP catabolic process GO:0006200 10 7 0,000 7,369E-03 0,02665692 ! establishment of pigment granule localization GO:0051905 13 7 0,000 7,369E-03 0,02661634 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 7,369E-03 0,02657589 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 7,369E-03 0,02653557 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 7,369E-03 0,02649536 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 7,369E-03 0,02645528 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 7,369E-03 0,02641532 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 7,369E-03 0,02637547 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 7,369E-03 0,02633575 ! muscle adaptation GO:0043500 12 7 0,000 7,369E-03 0,02629615 ! amino sugar catabolic process GO:0046348 9 7 0,000 7,369E-03 0,02625666 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 7,369E-03 0,0262173 ! retina homeostasis GO:0001895 9 7 0,000 7,369E-03 0,02617805 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 7,369E-03 0,02613892 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 7,369E-03 0,02609991 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 7,369E-03 0,02606101 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 7,369E-03 0,02602223 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 7,369E-03 0,02598356 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 8,418E-03 0,02963655 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 8,418E-03 0,02959264 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 8,418E-03 0,02954886 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 8,418E-03 0,02950522 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 8,418E-03 0,0294617 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 8,418E-03 0,02941831 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 8,418E-03 0,02937505 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 8,418E-03 0,02933191 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 8,418E-03 0,0292889 ! cell proliferation in forebrain GO:0021846 10 8 0,000 8,418E-03 0,02924602 ! neutral lipid catabolic process GO:0046461 11 8 0,000 8,418E-03 0,02920326 ! N-glycan processing GO:0006491 12 8 0,000 8,418E-03 0,02916063 ! Golgi to endosome transport GO:0006895 16 8 0,000 8,418E-03 0,02911812 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 8,418E-03 0,02907574 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 8,418E-03 0,02903348 ! mRNA stabilization GO:0048255 16 8 0,000 8,418E-03 0,02899134 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 8,418E-03 0,02894932 ! neurotransmitter uptake GO:0001504 10 8 0,000 8,418E-03 0,02890743 ! lipoprotein transport GO:0042953 14 8 0,000 8,418E-03 0,02886565 ! membrane hyperpolarization GO:0060081 11 8 0,000 8,418E-03 0,028824 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 8,418E-03 0,02878247 ! keratinocyte proliferation GO:0043616 15 8 0,000 8,418E-03 0,02874105 ! middle ear morphogenesis GO:0042474 9 8 0,000 8,418E-03 0,02869976 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 8,418E-03 0,02865858 ! bile acid and bile salt transport GO:0015721 12 8 0,000 8,418E-03 0,02861752 ! ganglioside metabolic process GO:0001573 16 8 0,000 8,418E-03 0,02857658 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 8,418E-03 0,02853576 ! reflex GO:0060004 16 8 0,000 8,418E-03 0,02849505 ! positive regulation of isotype switching GO:0045830 16 8 0,000 8,418E-03 0,02845446 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 8,418E-03 0,02841399 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 8,418E-03 0,02837362 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 8,418E-03 0,02833338 ! glycerolipid catabolic process GO:0046503 11 8 0,000 8,418E-03 0,02829325 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 8,418E-03 0,02825323 ! hemoglobin metabolic process GO:0020027 12 8 0,000 8,418E-03 0,02821332 ! ceramide biosynthetic process GO:0046513 9 8 0,000 8,418E-03 0,02817353 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 8,418E-03 0,02813385 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 8,418E-03 0,02809428 ! adrenal gland development GO:0030325 18 8 0,000 8,418E-03 0,02805482 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 8,418E-03 0,02801547 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 8,418E-03 0,02797623 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 8,418E-03 0,02793711 ! proline metabolic process GO:0006560 9 8 0,000 8,418E-03 0,02789809 ! polyamine biosynthetic process GO:0006596 9 8 0,000 8,418E-03 0,02785918 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 8,418E-03 0,02782038 ! regulation of pigmentation during development GO:0048070 18 8 0,000 8,418E-03 0,02778168 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 8,418E-03 0,0277431 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 8,418E-03 0,02770462 ! regulation of type I interferon production GO:0032479 8 8 0,000 8,418E-03 0,02766625 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 8,418E-03 0,02762798 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 8,418E-03 0,02758982 ! galactose metabolic process GO:0006012 14 8 0,000 8,418E-03 0,02755177 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 8,418E-03 0,02751382 ! regulation of vascular permeability GO:0043114 12 8 0,000 8,418E-03 0,02747597 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 8,418E-03 0,02743823 ! ruffle organization GO:0031529 12 8 0,000 8,418E-03 0,02740059 ! osteoblast development GO:0002076 14 8 0,000 8,418E-03 0,02736306 ! macroautophagy GO:0016236 14 8 0,000 8,418E-03 0,02732562 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 8,418E-03 0,02728829 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 8,418E-03 0,02725107 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 8,418E-03 0,02721394 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 8,418E-03 0,02717691 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 8,418E-03 0,02713999 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 8,418E-03 0,02710316 ! protein retention in ER lumen GO:0006621 16 8 0,000 8,418E-03 0,02706644 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 8,418E-03 0,02702981 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 8,418E-03 0,02699329 ! regulation of circadian rhythm GO:0042752 13 8 0,000 8,418E-03 0,02695686 ! pigment granule localization GO:0051875 14 8 0,000 8,418E-03 0,02692053 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 8,418E-03 0,0268843 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 8,418E-03 0,02684816 ! response to tropane GO:0014073 14 8 0,000 8,418E-03 0,02681212 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 8,418E-03 0,02677618 ! embryonic axis specification GO:0000578 12 8 0,000 8,418E-03 0,02674034 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 8,418E-03 0,02670459 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 8,418E-03 0,02666893 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 8,418E-03 0,02663338 ! snRNA metabolic process GO:0016073 10 8 0,000 8,418E-03 0,02659791 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 8,418E-03 0,02656254 ! regulation of focal adhesion formation GO:0051893 17 8 0,000 8,418E-03 0,02652727 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 8,418E-03 0,02649208 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 8,418E-03 0,026457 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 8,418E-03 0,026422 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 8,418E-03 0,0263871 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 8,418E-03 0,02635228 ! establishment of nucleus localization GO:0040023 14 8 0,000 8,418E-03 0,02631756 ! icosanoid secretion GO:0032309 12 8 0,000 8,418E-03 0,02628294 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 8,418E-03 0,0262484 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 8,418E-03 0,02621395 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 8,418E-03 0,0261796 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 8,418E-03 0,02614533 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 8,418E-03 0,02611115 ! S phase GO:0051320 8 8 0,000 8,418E-03 0,02607706 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 8,418E-03 0,02604307 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 8,418E-03 0,02600916 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 8,418E-03 0,02597533 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 8,418E-03 0,0259416 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 8,418E-03 0,02590795 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 8,418E-03 0,02587439 ! melanin biosynthetic process GO:0042438 11 8 0,000 8,418E-03 0,02584092 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 8,418E-03 0,02580753 ! regulation of synaptogenesis GO:0051963 12 8 0,000 8,418E-03 0,02577423 ! hormone catabolic process GO:0042447 13 8 0,000 8,418E-03 0,02574102 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 8,418E-03 0,02570789 ! quaternary ammonium group transport GO:0015697 10 8 0,000 8,418E-03 0,02567485 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 8,418E-03 0,02564189 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 8,418E-03 0,02560901 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 8,418E-03 0,02557622 ! regulation of telomere maintenance GO:0032204 10 8 0,000 8,418E-03 0,02554352 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 8,418E-03 0,0255109 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 8,418E-03 0,02547836 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 8,418E-03 0,0254459 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 8,418E-03 0,02541353 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 8,418E-03 0,02538123 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 8,418E-03 0,02534902 ! negative regulation of B cell activation GO:0050869 17 8 0,000 8,418E-03 0,0253169 ! behavioral response to nicotine GO:0035095 13 8 0,000 8,418E-03 0,02528485 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 8,418E-03 0,02525288 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 8,418E-03 0,025221 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 8,418E-03 0,02518919 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 8,418E-03 0,02515747 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 8,418E-03 0,02512583 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 9,465E-03 0,02821686 ! regulation of developmental growth GO:0048638 14 9 0,000 9,465E-03 0,02818146 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 9,465E-03 0,02814614 ! telencephalon cell migration GO:0022029 16 9 0,000 9,465E-03 0,02811092 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 9,465E-03 0,02807578 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 9,465E-03 0,02804073 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 9,465E-03 0,02800576 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 9,465E-03 0,02797089 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 9,465E-03 0,0279361 ! cell volume homeostasis GO:0006884 14 9 0,000 9,465E-03 0,02790139 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 9,465E-03 0,02786678 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 9,465E-03 0,02783224 ! UTP metabolic process GO:0046051 10 9 0,000 9,465E-03 0,0277978 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 9,465E-03 0,02776344 GO:0046457|prostanoid biosynthetic process, ! smoothened signaling pathway GO:0007224 10 9 0,000 9,465E-03 0,02772916 ! protein complex disassembly GO:0043241 17 9 0,000 9,465E-03 0,02769497 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 9,465E-03 0,02766086 ! estrogen metabolic process GO:0008210 16 9 0,000 9,465E-03 0,02762684 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 9,465E-03 0,0275929 ! photoreceptor cell development GO:0042461 17 9 0,000 9,465E-03 0,02755904 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 9,465E-03 0,02752527 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 9,465E-03 0,02749158 ! microtubule bundle formation GO:0001578 14 9 0,000 9,465E-03 0,02745797 ! T-helper 1 type immune response GO:0042088 13 9 0,000 9,465E-03 0,02742445 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 9,465E-03 0,027391 ! lung alveolus development GO:0048286 18 9 0,000 9,465E-03 0,02735764 ! ciliary or flagellar motility GO:0001539 10 9 0,000 9,465E-03 0,02732436 ! pseudouridine synthesis GO:0001522 10 9 0,000 9,465E-03 0,02729116 ! endothelial cell differentiation GO:0045446 17 9 0,000 9,465E-03 0,02725804 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 9,465E-03 0,027225 ! regulation of exit from mitosis GO:0007096 12 9 0,000 9,465E-03 0,02719204 ! endoderm development GO:0007492 12 9 0,000 9,465E-03 0,02715916 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 9,465E-03 0,02712635 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 9,465E-03 0,02709363 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 9,465E-03 0,02706099 ! astrocyte differentiation GO:0048708 17 9 0,000 9,465E-03 0,02702843 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 9,465E-03 0,02699594 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 9,465E-03 0,02696353 ! phosphagen metabolic process GO:0006599 12 9 0,000 9,465E-03 0,0269312 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 9,465E-03 0,02689895 ! reverse cholesterol transport GO:0043691 17 9 0,000 9,465E-03 0,02686677 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 9,465E-03 0,02683467 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 9,465E-03 0,02680265 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 9,465E-03 0,0267707 ! macrophage activation GO:0042116 14 9 0,000 9,465E-03 0,02673883 ! multicellular organism growth GO:0035264 16 9 0,000 9,465E-03 0,02670704 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 9,465E-03 0,02667532 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 9,465E-03 0,02664368 ! neuron apoptosis GO:0051402 12 9 0,000 9,465E-03 0,02661211 ! lens development in camera-type eye GO:0002088 11 9 0,000 9,465E-03 0,02658062 ! positive regulation of vasodilation GO:0045909 14 9 0,000 9,465E-03 0,0265492 ! retinoic acid metabolic process GO:0042573 11 9 0,000 9,465E-03 0,02651785 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 9,465E-03 0,02648658 ! positive regulation of translational initiation GO:0045948 10 9 0,000 9,465E-03 0,02645538 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 9,465E-03 0,02642426 ! Schwann cell differentiation GO:0014037 20 9 0,000 9,465E-03 0,02639321 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 9,465E-03 0,02636223 ! regulation of gliogenesis GO:0014013 21 9 0,000 9,465E-03 0,02633133 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 9,465E-03 0,02630049 ! oligodendrocyte development GO:0014003 13 9 0,000 9,465E-03 0,02626973 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 9,465E-03 0,02623904 ! segment specification GO:0007379 11 9 0,000 9,465E-03 0,02620843 ! cellular extravasation GO:0045123 12 9 0,000 9,465E-03 0,02617788 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 9,465E-03 0,02614741 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 9,465E-03 0,026117 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 9,465E-03 0,02608667 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 9,465E-03 0,02605641 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 9,465E-03 0,02602621 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 9,465E-03 0,02599609 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 9,465E-03 0,02596604 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 9,465E-03 0,02593605 ! response to amine stimulus GO:0014075 13 9 0,000 9,465E-03 0,02590614 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 9,465E-03 0,02587629 ! erythrocyte development GO:0048821 13 9 0,000 9,465E-03 0,02584651 ! renal water homeostasis GO:0003091 13 9 0,000 9,465E-03 0,02581681 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 9,465E-03 0,02578717 ! nucleosome disassembly GO:0006337 13 9 0,000 9,465E-03 0,02575759 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 9,465E-03 0,02572809 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 9,465E-03 0,02569865 ! induction of an organ GO:0001759 13 9 0,000 9,465E-03 0,02566928 ! leukocyte activation during immune response GO:0002366 15 9 0,000 9,465E-03 0,02563998 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 9,465E-03 0,02561074 ! cerebellum morphogenesis GO:0021587 13 9 0,000 9,465E-03 0,02558157 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 9,465E-03 0,02555247 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 9,465E-03 0,02552343 ! sterol catabolic process GO:0016127 11 9 0,000 9,465E-03 0,02549446 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 9,465E-03 0,02546556 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 9,465E-03 0,02543672 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 9,465E-03 0,02540794 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 9,465E-03 0,02537923 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 9,465E-03 0,02535059 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 9,465E-03 0,02532201 ! prophase GO:0051324 12 9 0,000 9,465E-03 0,02529349 ! neuroblast proliferation GO:0007405 19 9 0,000 9,465E-03 0,02526504 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 9,465E-03 0,02523665 ! peptidyl-threonine modification GO:0018210 22 9 0,000 9,465E-03 0,02520833 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 9,465E-03 0,02518007 ! ubiquinone metabolic process GO:0006743 11 9 0,000 9,465E-03 0,02515187 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 9,465E-03 0,02512374 ! acid secretion GO:0046717 14 9 0,000 9,465E-03 0,02509567 ! purine base metabolic process GO:0006144 18 9 0,000 9,465E-03 0,02506766 ! detection of calcium ion GO:0005513 13 9 0,000 9,465E-03 0,02503971 ! myeloid cell homeostasis GO:0002262 10 9 0,000 9,465E-03 0,02501183 ! regulation of fibrinolysis GO:0051917 14 9 0,000 9,465E-03 0,02498401 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 9,465E-03 0,02495625 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 9,465E-03 0,02492855 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 9,465E-03 0,02490091 ! regulation of muscle adaptation GO:0043502 12 9 0,000 9,465E-03 0,02487333 ! regulation of amino acid transport GO:0051955 11 9 0,000 9,465E-03 0,02484582 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 9,465E-03 0,02481837 ! prepulse inhibition GO:0060134 14 9 0,000 9,465E-03 0,02479097 ! sequestering of metal ion GO:0051238 12 9 0,000 9,465E-03 0,02476364 ! lamellipodium assembly GO:0030032 12 9 0,000 9,465E-03 0,02473637 ! regulation of embryonic development GO:0045995 17 9 0,000 9,465E-03 0,02470915 ! mitochondrion localization GO:0051646 15 9 0,000 9,465E-03 0,024682 ! localization within membrane GO:0051668 15 9 0,000 9,465E-03 0,02465491 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01051147 0,02735056 ! axon extension GO:0048675 13 10 0,000 0,01051147 0,0273206 ! neuron fate specification GO:0048665 12 10 0,000 0,01051147 0,02729071 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,01051147 0,02726089 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,01051147 0,02723112 ! associative learning GO:0008306 19 10 0,000 0,01051147 0,02720143 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,01051147 0,0271718 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01051147 0,02714223 ! CTP metabolic process GO:0046036 11 10 0,000 0,01051147 0,02711273 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,01051147 0,02708329 ! GTP metabolic process GO:0046039 11 10 0,000 0,01051147 0,02705392 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01051147 0,0270246 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,01051147 0,02699536 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01051147 0,02696617 ! social behavior GO:0035176 15 10 0,000 0,01051147 0,02693705 ! sulfate transport GO:0008272 12 10 0,000 0,01051147 0,02690799 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,01051147 0,026879 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,01051147 0,02685006 ! artery development GO:0060840 20 10 0,000 0,01051147 0,02682119 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,01051147 0,02679238 ! response to pain GO:0048265 20 10 0,000 0,01051147 0,02676364 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,01051147 0,02673495 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,01051147 0,02670633 ! phospholipid efflux GO:0033700 17 10 0,000 0,01051147 0,02667776 ! hippocampus development GO:0021766 19 10 0,000 0,01051147 0,02664926 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,01051147 0,02662082 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,01051147 0,02659244 ! blood vessel remodeling GO:0001974 23 10 0,000 0,01051147 0,02656412 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01051147 0,02653586 ! pathogenesis GO:0009405 13 10 0,000 0,01051147 0,02650766 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01051147 0,02647952 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,01051147 0,02645144 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,01051147 0,02642342 ! protein targeting to ER GO:0045047 21 10 0,000 0,01051147 0,02639546 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,01051147 0,02636756 ! arginine catabolic process GO:0006527 12 10 0,000 0,01051147 0,02633972 ! melanocyte differentiation GO:0030318 16 10 0,000 0,01051147 0,02631193 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,01051147 0,0262842 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01051147 0,02625654 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 0,000 0,01051147 0,02622893 ! regulation of stress fiber formation GO:0051492 24 10 0,000 0,01051147 0,02620138 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,01051147 0,02617388 ! B cell proliferation GO:0042100 16 10 0,000 0,01051147 0,02614645 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,01051147 0,02611907 ! mannose metabolic process GO:0006013 11 10 0,000 0,01051147 0,02609175 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01051147 0,02606448 ! forebrain cell migration GO:0021885 17 10 0,000 0,01051147 0,02603728 ! lipid digestion GO:0044241 15 10 0,000 0,01051147 0,02601013 ! substrate-bound cell migration GO:0006929 11 10 0,000 0,01051147 0,02598303 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01051147 0,02595599 ! receptor clustering GO:0043113 18 10 0,000 0,01051147 0,02592901 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01051147 0,02590209 ! UV protection GO:0009650 14 10 0,000 0,01051147 0,02587522 ! entry into host cell GO:0030260 21 10 0,000 0,01051147 0,0258484 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,01051147 0,02582165 ! behavioral fear response GO:0001662 19 10 0,000 0,01051147 0,02579494 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01051147 0,0257683 ! negative regulation of ossification GO:0030279 21 10 0,000 0,01051147 0,0257417 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,01051147 0,02571517 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,01051147 0,02568868 ! response to dsRNA GO:0043331 19 10 0,000 0,01051147 0,02566225 ! DNA ligation GO:0006266 16 10 0,000 0,01051147 0,02563588 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,01051147 0,02560956 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,01051147 0,02558329 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01051147 0,02555708 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01051147 0,02553092 ! positive regulation of Ras GTPase activity GO:0032320 24 10 0,000 0,01051147 0,02550482 ! postreplication repair GO:0006301 16 10 0,000 0,01051147 0,02547876 ! fucose catabolic process GO:0019317 17 10 0,000 0,01051147 0,02545277 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,01051147 0,02542682 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01051147 0,02540093 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,01051147 0,02537509 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,01051147 0,0253493 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,01051147 0,02532356 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01051147 0,02529788 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,01051147 0,02527225 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,01051147 0,02524667 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,01051147 0,02522114 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,01051147 0,02519567 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,01051147 0,02517024 ! oocyte differentiation GO:0009994 14 10 0,000 0,01051147 0,02514487 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,01051147 0,02511955 ! spleen development GO:0048536 17 10 0,000 0,01051147 0,02509428 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,01051147 0,02506906 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,01051147 0,02504389 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 0,01051147 0,02501877 ! blastocyst formation GO:0001825 14 10 0,000 0,01051147 0,0249937 ! embryonic gut development GO:0048566 13 10 0,000 0,01051147 0,02496868 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,01051147 0,02494371 ! cerebellar cortex development GO:0021695 14 10 0,000 0,01051147 0,02491879 ! activation of innate immune response GO:0002218 10 10 0,000 0,01051147 0,02489392 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01051147 0,0248691 ! insulin secretion GO:0030073 18 10 0,000 0,01051147 0,02484433 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 0,01051147 0,02481961 ! response to nicotine GO:0035094 18 10 0,000 0,01051147 0,02479494 ! establishment of cell polarity GO:0030010 12 10 0,000 0,01051147 0,02477032 ! nucleus localization GO:0051647 16 10 0,000 0,01051147 0,02474574 ! regulation of synapse organization GO:0050807 14 10 0,000 0,01051147 0,02472122 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,01155681 0,02715277 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,01155681 0,02712592 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,01155681 0,02709911 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,01155681 0,02707236 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,01155681 0,02704566 ! virus-host interaction GO:0019048 20 11 0,000 0,01155681 0,02701902 ! thyroid gland development GO:0030878 20 11 0,000 0,01155681 0,02699242 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,01155681 0,02696588 GO:0006740|NADPH regeneration, ! regulation of phosphatase activity GO:0010921 23 11 0,000 0,01155681 0,02693939 ! non-recombinational repair GO:0000726 19 11 0,000 0,01155681 0,02691295 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,01155681 0,02688657 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,01155681 0,02686024 ! Golgi vesicle budding GO:0048194 18 11 0,000 0,01155681 0,02683395 ! elastic fiber assembly GO:0048251 17 11 0,000 0,01155681 0,02680772 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,01155681 0,02678154 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,01155681 0,02675542 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,01155681 0,02672934 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,01155681 0,02670331 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,01155681 0,02667734 ! bone resorption GO:0045453 16 11 0,000 0,01155681 0,02665141 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,01155681 0,02662553 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,01155681 0,02659971 ! ventral spinal cord development GO:0021517 15 11 0,000 0,01155681 0,02657394 ! regulated secretory pathway GO:0045055 15 11 0,000 0,01155681 0,02654821 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 0,01155681 0,02652253 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,01155681 0,02649691 ! syncytium formation GO:0006949 15 11 0,000 0,01155681 0,02647133 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01155681 0,02644581 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,01155681 0,02642033 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,01155681 0,0263949 ! Golgi organization GO:0007030 19 11 0,000 0,01155681 0,02636952 ! response to X-ray GO:0010165 19 11 0,000 0,01155681 0,02634419 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,01155681 0,02631891 ! adult heart development GO:0007512 12 11 0,000 0,01155681 0,02629367 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01155681 0,02626849 ! epithelial cell development GO:0002064 16 11 0,000 0,01155681 0,02624335 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,01155681 0,02621826 ! temperature homeostasis GO:0001659 16 11 0,000 0,01155681 0,02619322 ! L-glutamate transport GO:0015813 15 11 0,000 0,01155681 0,02616823 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,01155681 0,02614328 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01155681 0,02611838 ! motor axon guidance GO:0008045 17 11 0,000 0,01155681 0,02609353 ! copper ion homeostasis GO:0055070 15 11 0,000 0,01155681 0,02606873 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,01155681 0,02604397 ! regulation of bone resorption GO:0045124 27 11 0,000 0,01155681 0,02601926 ! stem cell development GO:0048864 30 11 0,000 0,01155681 0,0259946 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,01155681 0,02596998 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,01155681 0,02594541 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,01155681 0,02592089 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,01155681 0,02589641 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01155681 0,02587198 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,01155681 0,0258476 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01155681 0,02582326 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,01155681 0,02579897 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,01155681 0,02577472 ! cranial nerve development GO:0021545 14 11 0,000 0,01155681 0,02575052 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01155681 0,02572636 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01155681 0,02570225 ! salivary gland development GO:0007431 24 11 0,000 0,01155681 0,02567818 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,01155681 0,02565416 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,01155681 0,02563019 ! musculoskeletal movement GO:0050881 16 11 0,000 0,01155681 0,02560626 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,01155681 0,02558237 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01155681 0,02555853 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01155681 0,02553473 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 20 11 0,000 0,01155681 0,02551098 ! digestive tract morphogenesis GO:0048546 16 11 0,000 0,01155681 0,02548727 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,01155681 0,0254636 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,01155681 0,02543998 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 0,01155681 0,0254164 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01155681 0,02539287 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,01155681 0,02536938 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01155681 0,02534593 ! regulation of actin filament bundle formation GO:0032231 25 11 0,000 0,01155681 0,02532253 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,01155681 0,02529917 ! defense response to fungus GO:0050832 13 11 0,000 0,01155681 0,02527585 ! lysogeny GO:0030069 20 11 0,000 0,01155681 0,02525258 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,01155681 0,02522935 ! acrosome reaction GO:0007340 14 11 0,000 0,01155681 0,02520616 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,01155681 0,02518301 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,01155681 0,02515991 ! rRNA transcription GO:0009303 19 12 0,000 0,01260109 0,02740825 ! reproductive cellular process GO:0048610 15 12 0,000 0,01260109 0,02738315 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01260109 0,02735809 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01260109 0,02733309 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01260109 0,02730812 ! phosphate transport GO:0006817 15 12 0,000 0,01260109 0,02728321 ! positive regulation of GTPase activity GO:0043547 29 12 0,000 0,01260109 0,02725834 ! peroxisomal transport GO:0043574 22 12 0,000 0,01260109 0,02723351 ! mating GO:0007618 16 12 0,000 0,01260109 0,02720873 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01260109 0,027184 ! heart looping GO:0001947 15 12 0,000 0,01260109 0,02715931 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01260109 0,02713466 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01260109 0,02711006 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01260109 0,0270855 ! T cell selection GO:0045058 25 12 0,000 0,01260109 0,02706099 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01260109 0,02703652 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,01260109 0,0270121 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01260109 0,02698772 ! plasma membrane organization GO:0007009 19 12 0,000 0,01260109 0,02696339 ! focal adhesion formation GO:0048041 28 12 0,000 0,01260109 0,0269391 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01260109 0,02691485 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01260109 0,02689064 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01260109 0,02686648 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01260109 0,02684237 ! monoamine transport GO:0015844 14 12 0,000 0,01260109 0,02681829 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01260109 0,02679426 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01260109 0,02677027 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01260109 0,02674633 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01260109 0,02672243 ! regulation of organ growth GO:0046620 14 12 0,000 0,01260109 0,02669857 ! vasoconstriction GO:0042310 18 12 0,000 0,01260109 0,02667475 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01260109 0,02665098 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01260109 0,02662724 ! regulation of Rho GTPase activity GO:0032319 22 12 0,000 0,01260109 0,02660355 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01260109 0,02657991 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01260109 0,0265563 ! histone deacetylation GO:0016575 14 12 0,000 0,01260109 0,02653274 ! histone acetylation GO:0016573 27 12 0,000 0,01260109 0,02650922 ! DNA methylation GO:0006306 19 12 0,000 0,01260109 0,02648574 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,01260109 0,0264623 ! protein sumoylation GO:0016925 14 12 0,000 0,01260109 0,0264389 ! chromatin silencing GO:0006342 23 12 0,000 0,01260109 0,02641554 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01260109 0,02639223 ! gland morphogenesis GO:0022612 24 12 0,000 0,01260109 0,02636896 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01260109 0,02634572 ! zymogen activation GO:0031638 16 12 0,000 0,01260109 0,02632253 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01260109 0,02629938 ! nucleosome positioning GO:0016584 13 12 0,000 0,01260109 0,02627627 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01260109 0,0262532 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01260109 0,02623017 ! response to gamma radiation GO:0010332 21 12 0,000 0,01260109 0,02620718 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01260109 0,02618423 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01260109 0,02616133 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01260109 0,02613846 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01260109 0,02611563 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01260109 0,02609284 ! male genitalia development GO:0030539 15 12 0,000 0,01260109 0,02607009 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01260109 0,02604738 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01260109 0,02602471 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01260109 0,02600208 ! developmental induction GO:0031128 16 12 0,000 0,01260109 0,02597949 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,01260109 0,02595694 ! response to cold GO:0009409 15 12 0,000 0,01260109 0,02593443 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01260109 0,02591195 ! respiratory burst GO:0045730 22 13 0,000 0,01364433 0,0280329 ! lactation GO:0007595 22 13 0,000 0,01364433 0,02800865 ! tRNA modification GO:0006400 15 13 0,000 0,01364433 0,02798444 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,01364433 0,02796027 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,01364433 0,02793615 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01364433 0,02791207 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,01364433 0,02788802 ! water transport GO:0006833 21 13 0,000 0,01364433 0,02786402 GO:0042044|fluid transport, ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,01364433 0,02784007 ! copper ion transport GO:0006825 15 13 0,000 0,01364433 0,02781615 ! filopodium assembly GO:0046847 21 13 0,000 0,01364433 0,02779227 ! lipid localization GO:0010876 25 13 0,000 0,01364433 0,02776844 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,01364433 0,02774464 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,01364433 0,02772089 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,01364433 0,02769717 ! T cell proliferation GO:0042098 24 13 0,000 0,01364433 0,0276735 ! organelle fusion GO:0048284 29 13 0,000 0,01364433 0,02764987 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01364433 0,02762628 ! endocrine pancreas development GO:0031018 19 13 0,000 0,01364433 0,02760273 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,01364433 0,02757921 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,01364433 0,02755574 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,01364433 0,02753231 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,01364433 0,02750892 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,01364433 0,02748557 ! methionine metabolic process GO:0006555 16 13 0,000 0,01364433 0,02746225 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,01364433 0,02743898 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01364433 0,02741575 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,01364433 0,02739255 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,01364433 0,0273694 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,01364433 0,02734628 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,01364433 0,0273232 ! neutral amino acid transport GO:0015804 20 13 0,000 0,01364433 0,02730017 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,01364433 0,02727717 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,01364433 0,02725421 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,01364433 0,02723128 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,01364433 0,0272084 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01364433 0,02718556 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01364433 0,02716275 ! cellular pigmentation GO:0033059 24 13 0,000 0,01364433 0,02713998 ! histone methylation GO:0016571 16 13 0,000 0,01364433 0,02711725 ! regulation of epidermis development GO:0045682 21 13 0,000 0,01364433 0,02709456 ! oxygen transport GO:0015671 20 13 0,000 0,01364433 0,0270719 ! regulation of axon extension GO:0030516 26 13 0,000 0,01364433 0,02704929 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,01364433 0,02702671 ! detection of bacterium GO:0016045 13 13 0,000 0,01364433 0,02700417 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,01364433 0,02698166 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,01364433 0,0269592 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,01364433 0,02693677 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,01364433 0,02691438 ! actin filament polymerization GO:0030041 18 13 0,000 0,01364433 0,02689202 ! regulation of protein ubiquitination GO:0031396 20 14 0,000 0,01468652 0,02892208 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,01468652 0,0288981 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,01468652 0,02887416 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,01468652 0,02885025 ! neuron maturation GO:0042551 24 14 0,000 0,01468652 0,02882639 ! regulation of S phase GO:0033261 25 14 0,000 0,01468652 0,02880257 ! regulation of chemokine production GO:0032642 18 14 0,000 0,01468652 0,02877878 ! myotube differentiation GO:0014902 21 14 0,000 0,01468652 0,02875504 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,01468652 0,02873133 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,01468652 0,02870767 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,01468652 0,02868404 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,01468652 0,02866045 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,01468652 0,0286369 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,01468652 0,02861339 ! RNA polyadenylation GO:0043631 21 14 0,000 0,01468652 0,02858992 ! cartilage condensation GO:0001502 22 14 0,000 0,01468652 0,02856648 ! gene silencing by RNA GO:0031047 22 14 0,000 0,01468652 0,02854309 ! response to cAMP GO:0051591 20 14 0,000 0,01468652 0,02851973 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,01468652 0,02849641 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,01468652 0,02847313 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,01468652 0,02844988 ! limbic system development GO:0021761 25 14 0,000 0,01468652 0,02842668 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,01468652 0,02840351 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,01468652 0,02838038 ! palate development GO:0060021 19 14 0,000 0,01468652 0,02835729 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,01468652 0,02833423 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,01468652 0,02831122 ! response to hexose stimulus GO:0009746 22 14 0,000 0,01468652 0,02828824 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,01468652 0,02826529 ! arginine metabolic process GO:0006525 17 14 0,000 0,01468652 0,02824239 ! glycine metabolic process GO:0006544 22 14 0,000 0,01468652 0,02821952 ! pituitary gland development GO:0021983 24 14 0,000 0,01468652 0,02819669 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,01468652 0,02817389 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,01468652 0,02815114 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,01468652 0,02812842 ! cytokine metabolic process GO:0042107 18 14 0,000 0,01468652 0,02810573 ! NAD metabolic process GO:0019674 25 14 0,000 0,01468652 0,02808308 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,01468652 0,02806047 ! regulation of heart rate GO:0002027 26 14 0,000 0,01468652 0,0280379 ! exocrine system development GO:0035272 29 14 0,000 0,01468652 0,02801536 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01468652 0,02799286 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,01468652 0,02797039 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,01468652 0,02794796 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,01468652 0,02792557 ! axon cargo transport GO:0008088 29 14 0,000 0,01468652 0,02790321 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,01468652 0,02788089 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,01468652 0,0278586 ! genitalia development GO:0048806 18 14 0,000 0,01468652 0,02783635 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,01468652 0,02781413 ! autonomic nervous system development GO:0048483 26 14 0,000 0,01468652 0,02779195 ! tissue regeneration GO:0042246 24 14 0,000 0,01468652 0,02776981 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,01468652 0,0277477 ! water homeostasis GO:0030104 23 14 0,000 0,01468652 0,02772562 ! cofactor transport GO:0051181 22 14 0,000 0,01468652 0,02770358 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,01468652 0,02768158 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,01468652 0,02765961 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01468652 0,02763767 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01468652 0,02761577 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,01468652 0,02759391 ! cell killing GO:0001906 22 14 0,000 0,01468652 0,02757208 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,01468652 0,02755028 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,01468652 0,02752852 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,01468652 0,02750679 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,01468652 0,0274851 ! microspike assembly GO:0030035 25 14 0,000 0,01468652 0,02746344 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,01468652 0,02744182 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,01572766 0,02936407 ! superoxide anion generation GO:0042554 19 15 0,000 0,01572766 0,02934098 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,01572766 0,02931793 ! skin development GO:0043588 28 15 0,000 0,01572766 0,02929492 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,01572766 0,02927194 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,01572766 0,029249 ! inositol metabolic process GO:0006020 21 15 0,000 0,01572766 0,0292261 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,01572766 0,02920323 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,01572766 0,0291804 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,01572766 0,0291576 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,01572766 0,02913484 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01572766 0,02911211 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,01572766 0,02908942 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,01572766 0,02906677 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,01572766 0,02904415 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01572766 0,02902156 ! response to osmotic stress GO:0006970 23 15 0,000 0,01572766 0,02899901 ! vesicle coating GO:0006901 26 15 0,000 0,01572766 0,0289765 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,01572766 0,02895402 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,01572766 0,02893157 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,01572766 0,02890916 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,01572766 0,02888679 ! bone mineralization GO:0030282 17 15 0,000 0,01572766 0,02886445 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,01572766 0,02884214 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,01572766 0,02881987 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,01572766 0,02879763 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,01572766 0,02877543 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,01572766 0,02875326 ! regulation of cellular pH GO:0030641 23 15 0,000 0,01572766 0,02873112 ! ribosome assembly GO:0042255 17 15 0,000 0,01572766 0,02870902 ! cerebellum development GO:0021549 19 15 0,000 0,01572766 0,02868695 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,01572766 0,02866492 ! mRNA splice site selection GO:0006376 33 15 0,000 0,01572766 0,02864292 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,01572766 0,02862096 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,01572766 0,02859903 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,01572766 0,02857713 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,01572766 0,02855526 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,01572766 0,02853343 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,01572766 0,02851163 ! muscle maintenance GO:0046716 21 15 0,000 0,01572766 0,02848987 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,01572766 0,02846814 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,01572766 0,02844644 ! intestinal absorption GO:0050892 22 15 0,000 0,01572766 0,02842477 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,01572766 0,02840314 ! dopamine metabolic process GO:0042417 32 15 0,000 0,01572766 0,02838154 ! gas transport GO:0015669 23 15 0,000 0,01572766 0,02835998 ! regulation of RNA stability GO:0043487 31 15 0,000 0,01572766 0,02833844 ! organic cation transport GO:0015695 19 15 0,000 0,01572766 0,02831694 ! heme biosynthetic process GO:0006783 22 15 0,000 0,01572766 0,02829547 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,01572766 0,02827404 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,01572766 0,02825263 ! release of cytochrome c from mitochondria GO:0001836 29 15 0,000 0,01572766 0,02823126 ! cilium assembly GO:0042384 22 15 0,000 0,01572766 0,02820992 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,01572766 0,02818862 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,01572766 0,02816734 ! peptide hormone processing GO:0016486 23 15 0,000 0,01572766 0,0281461 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,01572766 0,02812489 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,01676775 0,02996225 ! bone remodeling GO:0046849 24 16 0,000 0,01676775 0,0299397 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,01676775 0,02991719 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,01676775 0,02989471 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,01676775 0,02987227 ! bile acid metabolic process GO:0008206 23 16 0,000 0,01676775 0,02984986 ! axis specification GO:0009798 26 16 0,000 0,01676775 0,02982748 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,01676775 0,02980514 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,01676775 0,02978283 ! positive regulation of cell growth GO:0030307 22 16 0,000 0,01676775 0,02976056 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01676775 0,02973831 ! centrosome cycle GO:0007098 18 16 0,000 0,01676775 0,0297161 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,01676775 0,02969393 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,01676775 0,02967178 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,01676775 0,02964967 ! cellular response to starvation GO:0009267 26 16 0,000 0,01676775 0,0296276 ! DNA integration GO:0015074 25 16 0,000 0,01676775 0,02960555 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,01676775 0,02958354 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,01676775 0,02956156 ! regulation of exocytosis GO:0017157 28 16 0,000 0,01676775 0,02953962 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,01676775 0,0295177 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,01676775 0,02949582 ! regulation of vasodilation GO:0042312 26 16 0,000 0,01676775 0,02947397 ! DNA replication initiation GO:0006270 26 16 0,000 0,01676775 0,02945216 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,01676775 0,02943037 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,01676775 0,02940862 ! neuron recognition GO:0008038 27 16 0,000 0,01676775 0,0293869 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,01676775 0,02936521 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,01676775 0,02934356 ! G1 phase GO:0051318 28 16 0,000 0,01676775 0,02932193 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01676775 0,02930034 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,01676775 0,02927878 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,01676775 0,02925725 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,01676775 0,02923576 ! NADP metabolic process GO:0006739 22 16 0,000 0,01676775 0,02921429 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,01676775 0,02919286 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,01676775 0,02917145 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,01676775 0,02915008 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,01676775 0,02912874 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01676775 0,02910743 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,01676775 0,02908616 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,01676775 0,02906491 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,01676775 0,0290437 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,01676775 0,02902251 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,01676775 0,02900136 ! defense response to virus GO:0051607 28 16 0,000 0,01676775 0,02898024 ! peptide hormone secretion GO:0030072 26 16 0,000 0,01676775 0,02895914 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,01780679 0,03073128 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,01780679 0,03070895 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,01780679 0,03068665 ! zinc ion transport GO:0006829 22 17 0,000 0,01780679 0,03066438 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01780679 0,03064214 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,01780679 0,03061994 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,01780679 0,03059777 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,01780679 0,03057563 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,01780679 0,03055352 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,01780679 0,03053144 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,01780679 0,0305094 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,01780679 0,03048738 ! adult walking behavior GO:0007628 30 17 0,000 0,01780679 0,0304654 ! patterning of blood vessels GO:0001569 27 17 0,000 0,01780679 0,03044345 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,01780679 0,03042154 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,01780679 0,03039965 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 25 17 0,000 0,01780679 0,0303778 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01780679 0,03035597 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,01780679 0,03033418 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,01780679 0,03031242 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,01780679 0,03029069 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01780679 0,03026899 ! protein polyubiquitination GO:0000209 31 17 0,000 0,01780679 0,03024733 ! cerebral cortex development GO:0021987 34 17 0,000 0,01780679 0,03022569 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,01780679 0,03020408 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01780679 0,03018251 ! fructose metabolic process GO:0006000 24 17 0,000 0,01780679 0,03016097 ! membrane budding GO:0006900 30 17 0,000 0,01780679 0,03013945 ! neuromuscular junction development GO:0007528 25 17 0,000 0,01780679 0,03011797 ! L-amino acid transport GO:0015807 27 17 0,000 0,01780679 0,03009652 ! regulation of protein binding GO:0043393 29 17 0,000 0,01780679 0,0300751 ! peptide secretion GO:0002790 30 17 0,000 0,01780679 0,03005371 ! stem cell differentiation GO:0048863 40 17 0,000 0,01780679 0,03003235 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01780679 0,03001102 ! intermediate filament-based process GO:0045103 29 17 0,000 0,01780679 0,02998972 ! protein export from nucleus GO:0006611 26 17 0,000 0,01780679 0,02996845 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,01780679 0,02994721 ! diencephalon development GO:0021536 27 17 0,000 0,01780679 0,029926 ! oogenesis GO:0048477 25 17 0,000 0,01780679 0,02990482 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,01780679 0,02988367 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,01780679 0,02986255 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01780679 0,02984146 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,01780679 0,02982041 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,01780679 0,02979938 ! steroid catabolic process GO:0006706 24 17 0,000 0,01780679 0,02977837 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,01780679 0,0297574 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,01780679 0,02973646 ! nerve development GO:0021675 20 17 0,000 0,01780679 0,02971555 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,01780679 0,02969467 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,01780679 0,02967382 ! protein secretion GO:0009306 32 18 0,000 0,01884479 0,03138153 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,01884479 0,03135953 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,01884479 0,03133755 ! negative regulation of defense response GO:0031348 21 18 0,000 0,01884479 0,0313156 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,01884479 0,03129369 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,01884479 0,03127181 ! metencephalon development GO:0022037 25 18 0,000 0,01884479 0,03124995 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,01884479 0,03122813 ! hormone secretion GO:0046879 28 18 0,000 0,01884479 0,03120634 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,01884479 0,03118458 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,01884479 0,03116285 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,01884479 0,03114114 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01884479 0,03111947 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,01884479 0,03109783 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,01884479 0,03107622 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01884479 0,03105464 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,01884479 0,03103309 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,01884479 0,03101157 ! glial cell development GO:0021782 31 18 0,000 0,01884479 0,03099008 ! keratinization GO:0031424 19 18 0,000 0,01884479 0,03096862 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,01884479 0,03094719 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,01884479 0,03092578 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,01884479 0,03090441 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,01884479 0,03088307 ! vacuolar transport GO:0007034 26 18 0,000 0,01884479 0,03086176 ! pigmentation during development GO:0048066 35 18 0,000 0,01884479 0,03084047 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,01884479 0,03081922 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,01884479 0,03079799 ! fucose metabolic process GO:0006004 27 18 0,000 0,01884479 0,03077679 ! actin filament bundle formation GO:0051017 30 18 0,000 0,01884479 0,03075563 ! body fluid secretion GO:0007589 27 18 0,000 0,01884479 0,03073449 ! regulation of dephosphorylation GO:0035303 38 18 0,000 0,01884479 0,03071338 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,01884479 0,0306923 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,01884479 0,03067125 ! negative regulation of immune response GO:0050777 33 18 0,000 0,01884479 0,03065023 ! heart process GO:0003015 32 18 0,000 0,01884479 0,03062923 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,01884479 0,03060827 ! sensory perception of pain GO:0019233 26 18 0,000 0,01884479 0,03058733 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,01884479 0,03056643 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,01884479 0,03054555 ! somitogenesis GO:0001756 25 18 0,000 0,01884479 0,0305247 ! neural crest cell migration GO:0001755 28 18 0,000 0,01884479 0,03050388 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,01884479 0,03048308 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,01884479 0,03046232 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,01884479 0,03044158 ! synaptogenesis GO:0007416 28 18 0,000 0,01884479 0,03042087 ! cell-cell junction organization GO:0045216 28 18 0,000 0,01884479 0,03040019 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01884479 0,03037954 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,01884479 0,03035892 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,01884479 0,03033832 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,01884479 0,03031775 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,01884479 0,03029721 ! gut development GO:0048565 29 18 0,000 0,01884479 0,0302767 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,01884479 0,03025621 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,01884479 0,03023576 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,01884479 0,03021533 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,01988174 0,03185643 ! positive regulation of translation GO:0045727 29 19 0,000 0,01988174 0,03183493 ! positive regulation of cell size GO:0045793 26 19 0,000 0,01988174 0,03181347 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,01988174 0,03179203 ! glycerol metabolic process GO:0006071 22 19 0,000 0,01988174 0,03177062 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,01988174 0,03174924 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,01988174 0,03172789 ! endothelial cell migration GO:0043542 24 19 0,000 0,01988174 0,03170657 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,01988174 0,03168527 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,01988174 0,03166401 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,01988174 0,03164277 ! memory GO:0007613 28 19 0,000 0,01988174 0,03162156 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,01988174 0,03160038 ! pancreas development GO:0031016 27 19 0,000 0,01988174 0,03157923 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,01988174 0,03155811 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,01988174 0,03153701 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,01988174 0,03151595 ! central nervous system neuron development GO:0021954 33 19 0,000 0,01988174 0,03149491 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,01988174 0,0314739 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,01988174 0,03145292 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,01988174 0,03143196 ! heme metabolic process GO:0042168 29 19 0,000 0,01988174 0,03141103 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,01988174 0,03139014 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,01988174 0,03136926 ! response to fungus GO:0009620 21 19 0,000 0,01988174 0,03134842 ! peptide cross-linking GO:0018149 35 19 0,000 0,01988174 0,0313276 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,01988174 0,03130682 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,01988174 0,03128606 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,01988174 0,03126532 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,01988174 0,03124462 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,01988174 0,03122394 ! vitamin transport GO:0051180 26 19 0,000 0,01988174 0,03120329 ! sarcomere organization GO:0045214 26 19 0,000 0,01988174 0,03118267 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,01988174 0,03116207 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,01988174 0,0311415 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,01988174 0,03112096 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,01988174 0,03110044 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,01988174 0,03107996 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,01988174 0,0310595 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,02091765 0,03265631 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,02091765 0,03263484 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,02091765 0,03261339 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,02091765 0,03259198 ! lipid phosphorylation GO:0046834 28 20 0,000 0,02091765 0,03257059 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,02091765 0,03254924 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,02091765 0,03252791 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,02091765 0,03250661 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,02091765 0,03248533 ! response to alkaloid GO:0043279 34 20 0,000 0,02091765 0,03246408 ! sensory perception of taste GO:0050909 26 20 0,000 0,02091765 0,03244287 ! response to retinoic acid GO:0032526 27 20 0,000 0,02091765 0,03242168 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,02091765 0,03240051 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,02091765 0,03237938 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,02091765 0,03235827 ! chromosome condensation GO:0030261 32 20 0,000 0,02091765 0,03233719 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,02091765 0,03231614 ! sex determination GO:0007530 32 20 0,000 0,02091765 0,03229511 ! plasma membrane fusion GO:0045026 24 20 0,000 0,02091765 0,03227411 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,02091765 0,03225314 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,02091765 0,0322322 ! cytolysis GO:0019835 21 20 0,000 0,02091765 0,03221128 ! renal system process GO:0003014 35 20 0,000 0,02091765 0,03219039 ! vasodilation GO:0042311 36 20 0,000 0,02091765 0,03216953 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,02091765 0,0321487 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,02091765 0,03212789 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,02091765 0,03210711 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,02091765 0,03208635 ! hormone transport GO:0009914 30 20 0,000 0,02091765 0,03206562 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,02091765 0,03204492 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,02091765 0,03202425 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,02091765 0,0320036 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,02091765 0,03198298 ! sperm-egg recognition GO:0035036 24 20 0,000 0,02091765 0,03196239 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,02091765 0,03194182 ! negative regulation of translation GO:0017148 28 20 0,000 0,02091765 0,03192128 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,02091765 0,03190076 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,02195252 0,0334575 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,02195252 0,03343602 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02195252 0,03341458 ! positive regulation of ossification GO:0045778 34 21 0,000 0,02195252 0,03339316 ! iron ion transport GO:0006826 49 21 0,000 0,02195252 0,03337176 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,02195252 0,0333504 ! microtubule-based transport GO:0010970 41 21 0,000 0,02195252 0,03332906 ! vesicle docking GO:0048278 28 21 0,000 0,02195252 0,03330775 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,02195252 0,03328647 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,02195252 0,03326521 ! apoptotic mitochondrial changes GO:0008637 42 21 0,000 0,02195252 0,03324398 ! response to ethanol GO:0045471 38 21 0,000 0,02195252 0,03322278 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,02195252 0,03320161 ! smooth muscle contraction GO:0006939 39 21 0,000 0,02195252 0,03318046 ! response to vitamin A GO:0033189 28 21 0,000 0,02195252 0,03315934 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,02195252 0,03313825 GO:0042278|purine nucleoside metabolic process, ! apoptotic nuclear changes GO:0030262 31 21 0,000 0,02195252 0,03311718 ! response to starvation GO:0042594 35 21 0,000 0,02195252 0,03309614 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,02195252 0,03307513 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,02195252 0,03305414 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,02195252 0,03303318 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,02195252 0,03301225 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,02195252 0,03299134 ! visual learning GO:0008542 38 21 0,000 0,02195252 0,03297046 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 0,000 0,02195252 0,0329496 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,02195252 0,03292878 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,02195252 0,03290797 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02195252 0,0328872 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,02195252 0,03286645 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,02195252 0,03284573 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02195252 0,03282503 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,02195252 0,03280436 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,02195252 0,03278372 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02195252 0,0327631 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,02195252 0,0327425 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,02195252 0,03272194 ! embryonic pattern specification GO:0009880 34 22 0,000 0,02298634 0,03424143 ! regulation of cell killing GO:0031341 37 22 0,000 0,02298634 0,03421994 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,02298634 0,03419849 ! gluconeogenesis GO:0006094 26 22 0,000 0,02298634 0,03417706 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,02298634 0,03415566 ! viral genome replication GO:0019079 31 22 0,000 0,02298634 0,03413429 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,02298634 0,03411294 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,02298634 0,03409162 ! protein amino acid acylation GO:0043543 42 22 0,000 0,02298634 0,03407033 ! response to vitamin GO:0033273 31 22 0,000 0,02298634 0,03404906 ! molting cycle process GO:0022404 43 22 0,000 0,02298634 0,03402782 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,02298634 0,0340066 ! regeneration GO:0031099 37 22 0,000 0,02298634 0,03398541 ! phototransduction GO:0007602 29 22 0,000 0,02298634 0,03396425 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,02298634 0,03394312 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,02298634 0,03392201 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,02298634 0,03390093 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,02298634 0,03387987 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,02298634 0,03385884 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,02298634 0,03383784 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,02298634 0,03381686 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,02298634 0,0337959 ! pallium development GO:0021543 43 22 0,000 0,02298634 0,03377498 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,02298634 0,03375408 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,02298634 0,0337332 ! platelet activation GO:0030168 33 22 0,000 0,02298634 0,03371236 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,02298634 0,03369153 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,02298634 0,03367073 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,02298634 0,03364996 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,02298634 0,03362922 ! cell-cell recognition GO:0009988 28 22 0,000 0,02298634 0,0336085 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,02298634 0,0335878 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,02298634 0,03356713 ! alditol metabolic process GO:0019400 26 22 0,000 0,02298634 0,03354649 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,02401913 0,0350322 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,02401913 0,03501068 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,02401913 0,03498919 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,02401913 0,03496772 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,02401913 0,03494628 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,02401913 0,03492487 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,02401913 0,03490348 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,02401913 0,03488212 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,02401913 0,03486079 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,02401913 0,03483948 ! dendrite development GO:0016358 41 23 0,000 0,02401913 0,0348182 ! vasculogenesis GO:0001570 38 23 0,000 0,02401913 0,03479694 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,02401913 0,03477571 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,02401913 0,0347545 ! lysosome organization GO:0007040 41 23 0,000 0,02401913 0,03473333 ! digestive system process GO:0022600 35 23 0,000 0,02401913 0,03471217 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,02401913 0,03469104 ! vesicle targeting GO:0006903 35 23 0,000 0,02401913 0,03466994 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,02401913 0,03464887 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,02401913 0,03462782 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,02401913 0,03460679 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,02401913 0,03458579 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,02401913 0,03456482 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,02401913 0,03454387 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,02401913 0,03452295 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,02401913 0,03450205 ! membrane depolarization GO:0051899 40 23 0,000 0,02401913 0,03448118 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02401913 0,03446033 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,02401913 0,03443951 ! DNA modification GO:0006304 33 23 0,000 0,02401913 0,03441871 ! collagen fibril organization GO:0030199 50 23 0,000 0,02401913 0,03439794 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,02401913 0,03437719 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,02401913 0,03435647 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,02401913 0,03433578 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,02401913 0,0343151 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02401913 0,03429446 ! collagen catabolic process GO:0030574 29 23 0,000 0,02401913 0,03427383 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,02401913 0,03425324 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,02401913 0,03423266 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,02401913 0,03421212 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,02401913 0,03419159 ! blastocyst development GO:0001824 41 23 0,000 0,02401913 0,0341711 ! actin filament-based movement GO:0030048 37 23 0,000 0,02401913 0,03415062 ! protein stabilization GO:0050821 34 23 0,000 0,02401913 0,03413017 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,02505087 0,03557493 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,02505087 0,03555366 ! myelination GO:0042552 39 24 0,000 0,02505087 0,03553241 ! initiation of viral infection GO:0019059 47 24 0,000 0,02505087 0,03551118 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,02505087 0,03548998 ! leukocyte adhesion GO:0007159 49 24 0,000 0,02505087 0,0354688 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,02505087 0,03544765 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,02505087 0,03542653 ! visual behavior GO:0007632 42 24 0,000 0,02505087 0,03540543 ! spinal cord development GO:0021510 41 24 0,000 0,02505087 0,03538435 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,02505087 0,03536331 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 0,000 0,02505087 0,03534228 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,02505087 0,03532128 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,02505087 0,03530031 ! cell aging GO:0007569 38 24 0,000 0,02505087 0,03527936 ! osteoblast differentiation GO:0001649 43 24 0,000 0,02505087 0,03525843 ! response to toxin GO:0009636 38 24 0,000 0,02505087 0,03523753 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,02505087 0,03521666 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,02505087 0,03519581 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,02505087 0,03517498 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,02505087 0,03515418 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,02505087 0,0351334 ! pentose metabolic process GO:0019321 33 24 0,000 0,02505087 0,03511265 ! immunoglobulin production GO:0002377 37 24 0,000 0,02505087 0,03509192 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,02505087 0,03507122 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,02505087 0,03505054 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,02505087 0,03502989 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,02505087 0,03500926 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,02505087 0,03498865 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,02505087 0,03496807 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,02505087 0,03494751 ! neuron fate commitment GO:0048663 38 25 0,000 0,02608158 0,03636403 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,02608158 0,03634268 ! superoxide metabolic process GO:0006801 33 25 0,000 0,02608158 0,03632135 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,02608158 0,03630005 GO:0050908|detection of light stimulus involved in visual perception, ! regulation of cell-matrix adhesion GO:0001952 57 25 0,000 0,02608158 0,03627877 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,02608158 0,03625752 ! vacuole organization GO:0007033 43 25 0,000 0,02608158 0,03623629 ! receptor metabolic process GO:0043112 40 25 0,000 0,02608158 0,03621508 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,02608158 0,03619391 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,02608158 0,03617275 ! regulation of behavior GO:0050795 45 25 0,000 0,02608158 0,03615162 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,02608158 0,03613052 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,02608158 0,03610944 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,02608158 0,03608838 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,02608158 0,03606735 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,02608158 0,03604635 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,02608158 0,03602537 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,02608158 0,03600441 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,02608158 0,03598348 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,02608158 0,03596257 ! regulation of amine transport GO:0051952 44 25 0,000 0,02608158 0,03594168 ! liver development GO:0001889 44 25 0,000 0,02608158 0,03592082 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,02711124 0,03731727 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,02711124 0,03729564 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,02711124 0,03727403 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,02711124 0,03725245 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,02711124 0,03723089 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,02711124 0,03720936 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,02711124 0,03718785 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,02711124 0,03716637 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,02711124 0,03714491 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,02711124 0,03712347 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,02711124 0,03710207 ! sperm motility GO:0030317 31 26 0,000 0,02711124 0,03708068 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,02711124 0,03705932 ! male gonad development GO:0008584 39 26 0,000 0,02711124 0,03703799 ! neural crest cell development GO:0014032 44 26 0,000 0,02711124 0,03701667 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,02711124 0,03699539 ! cell fate determination GO:0001709 54 26 0,000 0,02711124 0,03697413 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,02711124 0,03695289 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,02711124 0,03693168 ! detection of visible light GO:0009584 33 26 0,000 0,02711124 0,03691049 ! spermatid development GO:0007286 40 26 0,000 0,02711124 0,03688932 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,02711124 0,03686818 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,02711124 0,03684707 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,02711124 0,03682598 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,02711124 0,03680491 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02813987 0,03817949 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,02813987 0,03815767 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,02813987 0,03813588 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,02813987 0,03811411 ! membrane docking GO:0022406 40 27 0,000 0,02813987 0,03809237 ! circadian rhythm GO:0007623 44 27 0,000 0,02813987 0,03807065 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,02813987 0,03804896 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,02813987 0,03802729 ! autophagy GO:0006914 36 27 0,000 0,02813987 0,03800565 ! myofibril assembly GO:0030239 40 27 0,000 0,02813987 0,03798403 GO:0055002|striated muscle cell development, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,02813987 0,03796243 ! peptide transport GO:0015833 46 27 0,000 0,02813987 0,03794086 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,02813987 0,03791932 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,02813987 0,0378978 ! negative regulation of cell development GO:0010721 67 27 0,000 0,02813987 0,0378763 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,02813987 0,03785483 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,02813987 0,03783338 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,02813987 0,03781196 ! detection of light stimulus GO:0009583 35 27 0,000 0,02813987 0,03779056 ! lipid oxidation GO:0034440 39 27 0,000 0,02813987 0,03776919 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,02813987 0,03774784 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,02813987 0,03772651 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,02813987 0,03770521 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,02916747 0,03906005 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,02916747 0,03903802 ! translational initiation GO:0006413 48 28 0,000 0,02916747 0,03901601 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,02916747 0,03899403 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,02916747 0,03897207 ! regulation of pH GO:0006885 40 28 0,000 0,02916747 0,03895014 ! negative regulation of protein modification process GO:0031400 56 28 0,000 0,02916747 0,03892824 ! catechol metabolic process GO:0009712 46 28 0,000 0,02916747 0,03890635 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,02916747 0,0388845 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,02916747 0,03886266 ! iron ion homeostasis GO:0055072 49 28 0,000 0,02916747 0,03884086 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,02916747 0,03881907 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,02916747 0,03879731 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,02916747 0,03877558 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,02916747 0,03875387 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,02916747 0,03873218 ! gene silencing GO:0016458 47 28 0,000 0,02916747 0,03871052 ! regulation of coagulation GO:0050818 42 28 0,000 0,02916747 0,03868888 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,03019403 0,04002817 ! phenol metabolic process GO:0018958 47 29 0,000 0,03019403 0,04000582 ! positive regulation of cell adhesion GO:0045785 54 29 0,000 0,03019403 0,0399835 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,03019403 0,0399612 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,03019403 0,03993893 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,03019403 0,03991667 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,03019403 0,03989445 ! cholesterol transport GO:0030301 48 29 0,000 0,03019403 0,03987225 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,03019403 0,03985007 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,03019403 0,03982792 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,03019403 0,0398058 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,03019403 0,03978369 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,03019403 0,03976162 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,03019403 0,03973956 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,03019403 0,03971753 ! response to ionizing radiation GO:0010212 55 29 0,000 0,03019403 0,03969553 ! muscle cell development GO:0055001 42 29 0,000 0,03019403 0,03967355 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,03019403 0,03965159 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,03019403 0,03962966 ! mesoderm formation GO:0001707 52 29 0,000 0,03019403 0,03960776 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,03019403 0,03958587 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,03019403 0,03956402 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,03019403 0,03954218 ! ensheathment of neurons GO:0007272 48 29 0,000 0,03019403 0,03952037 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,03019403 0,03949858 ! spermatid differentiation GO:0048515 45 29 0,000 0,03019403 0,03947682 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,03121956 0,04079516 ! organic anion transport GO:0015711 50 30 0,000 0,03121956 0,04077271 ! cell junction assembly GO:0034329 65 30 0,000 0,03121956 0,04075028 ! acute-phase response GO:0006953 49 30 0,000 0,03121956 0,04072788 ! segmentation GO:0035282 43 30 0,000 0,03121956 0,0407055 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,03121956 0,04068314 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,03121956 0,04066082 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,03121956 0,04063851 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,03121956 0,04061623 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,03121956 0,04059398 ! formation of primary germ layer GO:0001704 54 30 0,000 0,03121956 0,04057174 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,03121956 0,04054954 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,03121956 0,04052736 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,03121956 0,0405052 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,03121956 0,04048306 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,03121956 0,04046095 ! response to heat GO:0009408 43 30 0,000 0,03121956 0,04043887 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,03121956 0,04041681 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,03224405 0,04172035 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,03224405 0,04169762 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,03224405 0,04167491 ! regulation of innate immune response GO:0045088 42 31 0,000 0,03224405 0,04165222 ! ovulation cycle process GO:0022602 46 31 0,000 0,03224405 0,04162956 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,03224405 0,04160692 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,03224405 0,04158431 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,03224405 0,04156172 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,03224405 0,04153916 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,03224405 0,04151662 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,03224405 0,0414941 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,03224405 0,04147161 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,03224405 0,04144915 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,03224405 0,04142671 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,03224405 0,04140429 ! tissue homeostasis GO:0001894 45 31 0,000 0,03224405 0,0413819 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,03326751 0,04267233 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,03326751 0,04264927 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,03326751 0,04262624 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,03326751 0,04260324 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,03326751 0,04258026 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,03326751 0,04255731 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,03326751 0,04253438 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,03326751 0,04251147 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,03326751 0,04248859 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,03326751 0,04246574 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,03326751 0,0424429 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,03326751 0,0424201 ! telencephalon development GO:0021537 59 32 0,000 0,03326751 0,04239732 ! ovulation cycle GO:0042698 48 32 0,000 0,03326751 0,04237456 ! cofactor catabolic process GO:0051187 52 32 0,000 0,03326751 0,04235183 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,03326751 0,04232912 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,03326751 0,04230643 ! placenta development GO:0001890 45 32 0,000 0,03326751 0,04228377 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,03326751 0,04226114 ! vesicle localization GO:0051648 50 32 0,000 0,03326751 0,04223852 ! regulation of muscle development GO:0048634 52 33 0,000 0,03428994 0,04351339 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,03428994 0,04349013 ! negative regulation of secretion GO:0051048 53 33 0,000 0,03428994 0,0434669 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,03428994 0,04344369 ! glial cell differentiation GO:0010001 65 33 0,000 0,03428994 0,04342051 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,03428994 0,04339735 ! sister chromatid segregation GO:0000819 48 33 0,000 0,03428994 0,04337422 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,03428994 0,04335111 ! spindle organization GO:0007051 39 33 0,000 0,03428994 0,04332802 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,03428994 0,04330497 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,03428994 0,04328193 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,03428994 0,04325892 ! protein targeting to membrane GO:0006612 63 33 0,000 0,03428994 0,04323594 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,03428994 0,04321297 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,03428994 0,04319004 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,03428994 0,04316712 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,03428994 0,04314424 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,03428994 0,04312137 ! cytokine production GO:0001816 49 33 0,000 0,03428994 0,04309853 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,03428994 0,04307572 ! RNA modification GO:0009451 43 33 0,000 0,03428994 0,04305293 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,03428994 0,04303016 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,03531134 0,04428849 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,03531134 0,04426509 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,03531134 0,04424172 ! actomyosin structure organization GO:0031032 48 34 0,000 0,03531134 0,04421837 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,03531134 0,04419505 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,03531134 0,04417175 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,03531134 0,04414848 ! positive regulation of cell development GO:0010720 58 34 0,000 0,03531134 0,04412523 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,03531134 0,04410201 ! cell fate specification GO:0001708 49 34 0,000 0,03531134 0,04407881 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 0,000 0,03531134 0,04405563 ! peripheral nervous system development GO:0007422 58 34 0,000 0,03531134 0,04403248 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,03531134 0,04400936 ! adult locomotory behavior GO:0008344 54 34 0,000 0,03531134 0,04398625 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,03531134 0,04396318 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,03633171 0,04520984 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,03633171 0,04518614 ! collagen metabolic process GO:0032963 47 35 0,000 0,03633171 0,04516247 ! cell junction organization GO:0034330 72 35 0,000 0,03633171 0,04513883 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,03633171 0,0451152 ! metanephros development GO:0001656 61 35 0,000 0,03633171 0,04509161 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,03633171 0,04506804 ! female gonad development GO:0008585 55 35 0,000 0,03633171 0,04504449 ! lipid homeostasis GO:0055088 63 35 0,000 0,03633171 0,04502097 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,03633171 0,04499747 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,03633171 0,044974 ! negative regulation of hydrolase activity GO:0051346 56 35 0,000 0,03633171 0,04495055 ! hindbrain development GO:0030902 56 35 0,000 0,03633171 0,04492713 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,03633171 0,04490373 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,03633171 0,04488035 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,03633171 0,044857 ! cytokinesis GO:0000910 57 35 0,000 0,03633171 0,04483367 ! embryonic organ development GO:0048568 53 35 0,000 0,03633171 0,04481037 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,03633171 0,04478709 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,03633171 0,04476384 ! meiosis I GO:0007127 61 36 0,000 0,03735106 0,04599588 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,03735106 0,04597202 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,03735106 0,04594819 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,03735106 0,04592438 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,03735106 0,0459006 ! spliceosome assembly GO:0000245 65 36 0,000 0,03735106 0,04587684 ! mismatch repair GO:0006298 42 36 0,000 0,03735106 0,04585311 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,03735106 0,0458294 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,03735106 0,04580572 ! regulation of proteolysis GO:0030162 53 36 0,000 0,03735106 0,04578206 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,03735106 0,04575842 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,03735106 0,04573481 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,03735106 0,04571122 ! eye morphogenesis GO:0048592 64 36 0,000 0,03735106 0,04568766 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,03735106 0,04566412 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,03836937 0,04688493 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,03836937 0,0468608 ! mammary gland development GO:0030879 73 37 0,000 0,03836937 0,04683669 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,03836937 0,04681261 ! ear morphogenesis GO:0042471 50 37 0,000 0,03836937 0,04678855 ! odontogenesis GO:0042476 60 37 0,000 0,03836937 0,04676452 ! negative regulation of binding GO:0051100 59 37 0,000 0,03836937 0,04674052 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,03836937 0,04671653 ! tissue remodeling GO:0048771 65 37 0,000 0,03836937 0,04669258 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,03836937 0,04666864 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 58 37 0,000 0,03836937 0,04664474 ! keratinocyte differentiation GO:0030216 55 37 0,000 0,03836937 0,04662085 ! natural killer cell activation GO:0030101 45 37 0,000 0,03836937 0,04659699 ! polyol metabolic process GO:0019751 47 37 0,000 0,03836937 0,04657316 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,03836937 0,04654935 ! glucan metabolic process GO:0044042 54 37 0,000 0,03836937 0,04652556 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,03938667 0,04773471 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,03938667 0,04771034 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,03938667 0,047686 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,03938667 0,04766168 ! feeding behavior GO:0007631 50 38 0,000 0,03938667 0,04763739 ! organic ether metabolic process GO:0018904 51 38 0,000 0,03938667 0,04761312 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,03938667 0,04758888 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,03938667 0,04756466 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,03938667 0,04754047 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,03938667 0,0475163 ! ion transmembrane transport GO:0034220 58 38 0,000 0,03938667 0,04749215 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,03938667 0,04746803 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,03938667 0,04744394 ! neuron migration GO:0001764 59 38 0,000 0,03938667 0,04741987 ! maintenance of protein location GO:0045185 72 38 0,000 0,03938667 0,04739582 ! pigment metabolic process GO:0042440 66 38 0,000 0,03938667 0,0473718 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,03938667 0,0473478 ! mRNA catabolic process GO:0006402 58 39 0,000 0,04040293 0,04854489 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,04040293 0,04852032 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,04040293 0,04849578 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,04040293 0,04847126 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,04040293 0,04844677 ! regulation of protein stability GO:0031647 58 39 0,000 0,04040293 0,0484223 ! female gamete generation GO:0007292 50 39 0,000 0,04040293 0,04839786 ! aerobic respiration GO:0009060 56 39 0,000 0,04040293 0,04837344 ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,04040293 0,04834904 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,04141817 0,04953897 ! Notch signaling pathway GO:0007219 64 40 0,000 0,04141817 0,04951402 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,04141817 0,04948909 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,04141817 0,04946418 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,04141817 0,0494393 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,04141817 0,04941444 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,04141817 0,04938961 ! phagocytosis GO:0006909 65 40 0,000 0,04141817 0,0493648 ! mesenchymal cell development GO:0014031 70 40 0,000 0,04141817 0,04934002 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,04141817 0,04931527 ! B cell differentiation GO:0030183 70 40 0,000 0,04141817 0,04929053 ! pigmentation GO:0043473 81 40 0,000 0,04141817 0,04926583 ! developmental growth GO:0048589 70 40 0,000 0,04141817 0,04924114 ! synapse organization GO:0050808 61 40 0,000 0,04141817 0,04921649 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,04243239 0,05039643 ! RNA export from nucleus GO:0006405 57 41 0,000 0,04243239 0,05037122 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,04243239 0,05034603 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,04243239 0,05032087 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,04243239 0,05029574 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,04243239 0,05027063 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,04243239 0,05024554 ! cell growth GO:0016049 71 41 0,000 0,04243239 0,05022048 ! maintenance of location in cell GO:0051651 77 41 0,000 0,04243239 0,05019545 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,04344559 0,0513684 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,04344559 0,05134282 ! learning GO:0007612 75 42 0,000 0,04344559 0,05131726 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,04344559 0,05129173 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,04344559 0,05126623 ! gliogenesis GO:0042063 85 42 0,000 0,04344559 0,05124075 ! endosome transport GO:0016197 74 42 0,000 0,04344559 0,05121529 ! male sex differentiation GO:0046661 62 42 0,000 0,04344559 0,05118986 ! double-strand break repair GO:0006302 75 42 0,000 0,04344559 0,05116446 ! epidermal cell differentiation GO:0009913 61 42 0,000 0,04344559 0,05113908 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,04344559 0,05111372 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,04344559 0,0510884 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,04445777 0,05225274 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,04445777 0,05222687 ! regulation of tube size GO:0035150 69 43 0,000 0,04445777 0,05220103 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,04445777 0,05217521 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,04445777 0,05214942 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,04445777 0,05212365 ! T cell differentiation GO:0030217 78 43 0,000 0,04445777 0,05209791 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,04445777 0,0520722 ! amino acid activation GO:0043038 61 43 0,000 0,04445777 0,05204651 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,04445777 0,05202085 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,04546892 0,0531778 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,04546892 0,0531516 ! cellular component disassembly GO:0022411 66 44 0,000 0,04546892 0,05312543 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,04546892 0,05309929 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,04546892 0,05307317 ! inner ear development GO:0048839 66 44 0,000 0,04546892 0,05304707 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,04546892 0,05302101 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,04546892 0,05299497 ! chromatin remodeling GO:0006338 73 44 0,000 0,04546892 0,05296895 ! biopolymer methylation GO:0043414 67 44 0,000 0,04546892 0,05294296 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,04546892 0,05291699 ! JNK cascade GO:0007254 66 44 0,000 0,04546892 0,05289105 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,04546892 0,05286514 ! regulation of cell shape GO:0008360 83 44 0,000 0,04546892 0,05283925 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,04647906 0,05398669 ! positive regulation of binding GO:0051099 67 45 0,000 0,04647906 0,05396028 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,04647906 0,05393389 ! regulation of ion transport GO:0043269 60 45 0,000 0,04647906 0,05390753 ! glucose transport GO:0015758 60 45 0,000 0,04647906 0,05388119 ! neuromuscular process GO:0050905 89 45 0,000 0,04647906 0,05385488 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,04647906 0,0538286 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,04647906 0,05380234 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,04647906 0,05377611 ! response to insulin stimulus GO:0032868 71 45 0,000 0,04647906 0,0537499 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,04748818 0,05489013 ! regulation of translational initiation GO:0006446 70 46 0,000 0,04748818 0,05486341 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,04748818 0,05483671 ! regulation of action potential GO:0001508 80 46 0,000 0,04748818 0,05481004 ! hexose transport GO:0008645 62 46 0,000 0,04748818 0,05478339 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,04748818 0,05475677 ! excretion GO:0007588 72 46 0,000 0,04748818 0,05473018 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,04748818 0,05470361 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,04748818 0,05467707 ! positive regulation of defense response GO:0031349 70 47 0,000 0,04849628 0,0558107 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,04849628 0,05578365 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,04849628 0,05575662 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,04849628 0,05572962 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,04849628 0,05570265 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,04849628 0,0556757 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,04950336 0,05680439 ! viral infectious cycle GO:0019058 80 48 0,000 0,04950336 0,05677694 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,04950336 0,05674951 ! leukocyte migration GO:0050900 76 48 0,000 0,04950336 0,05672211 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,04950336 0,05669473 ! striated muscle contraction GO:0006941 78 48 0,000 0,04950336 0,05666738 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,04950336 0,05664006 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,04950336 0,05661276 ! tRNA processing GO:0008033 56 48 0,000 0,04950336 0,05658549 ! cell maturation GO:0048469 69 48 0,000 0,04950336 0,05655825 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,04950336 0,05653103 ! vesicle organization GO:0016050 87 48 0,000 0,04950336 0,05650384 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,04950336 0,05647667 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,05050943 0,05759677 ! glycolysis GO:0006096 63 49 0,000 0,05050943 0,05756911 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,05050943 0,05754147 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,05050943 0,05751386 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,05050943 0,05748628 ! response to temperature stimulus GO:0009266 66 49 0,000 0,05050943 0,05745872 ! endocrine system development GO:0035270 86 49 0,000 0,05050943 0,05743119 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,05050943 0,05740368 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,05050943 0,0573762 ! gastrulation GO:0007369 80 49 0,000 0,05050943 0,05734875 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,05050943 0,05732132 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,05050943 0,05729392 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,05050943 0,05726655 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,05050943 0,0572392 ! methylation GO:0032259 74 49 0,000 0,05050943 0,05721188 ! cell redox homeostasis GO:0045454 72 50 0,000 0,05151449 0,05832246 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,05151449 0,05829465 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,05151449 0,05826686 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,05151449 0,05823911 ! histone modification GO:0016570 81 50 0,000 0,05151449 0,05821137 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,05151449 0,05818367 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,05151449 0,05815599 ! RNA catabolic process GO:0006401 77 51 0,000 0,05251853 0,05926128 ! chloride transport GO:0006821 78 51 0,000 0,05251853 0,05923312 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,05251853 0,05920498 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,05251853 0,05917686 ! regulation of ossification GO:0030278 82 51 0,000 0,05251853 0,05914878 ! heart morphogenesis GO:0003007 71 51 0,000 0,05251853 0,05912072 ! RNA elongation GO:0006354 67 51 0,000 0,05251853 0,05909269 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,05251853 0,05906468 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,05352156 0,06016422 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,05352156 0,06013573 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,05352156 0,06010727 ! regulation of DNA replication GO:0006275 88 52 0,000 0,05352156 0,06007884 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,05352156 0,06005043 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,05352156 0,06002205 ! covalent chromatin modification GO:0016569 90 52 0,000 0,05352156 0,0599937 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,05352156 0,05996538 ! proton transport GO:0015992 78 52 0,000 0,05352156 0,05993708 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,05352156 0,0599088 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,05352156 0,05988056 ! transition metal ion transport GO:0000041 88 53 0,000 0,05452358 0,06097288 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,05452358 0,06094416 ! muscle fiber development GO:0048747 80 53 0,000 0,05452358 0,06091547 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,05452358 0,0608868 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,05452358 0,06085816 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,05452358 0,06082955 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,05452358 0,06080097 ! regulation of endocytosis GO:0030100 71 53 0,000 0,05452358 0,06077241 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,05452358 0,06074388 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,05452358 0,06071537 ! maintenance of location GO:0051235 94 53 0,000 0,05452358 0,06068689 ! hydrogen transport GO:0006818 81 54 0,000 0,05552459 0,06177208 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,05552459 0,06174313 ! regulation of mitosis GO:0007088 91 54 0,000 0,05552459 0,06171422 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,05552459 0,06168532 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,05552459 0,06165646 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,05552459 0,06162762 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,05552459 0,06159881 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,05552459 0,06157002 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,05552459 0,06154127 ! germ cell development GO:0007281 82 54 0,000 0,05552459 0,06151253 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,05552459 0,06148383 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,05552459 0,06145515 ! establishment of organelle localization GO:0051656 91 54 0,000 0,05552459 0,0614265 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,05652459 0,06250366 ! ear development GO:0043583 83 55 0,000 0,05652459 0,06247454 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,05652459 0,06244546 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,05652459 0,0624164 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,05652459 0,06238737 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,05652459 0,06235837 ! regulation of actin filament length GO:0030832 88 56 0,000 0,05752358 0,06343097 ! positive regulation of secretion GO:0051047 83 56 0,000 0,05752358 0,06340151 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,05752358 0,06337208 ! DNA catabolic process GO:0006308 71 56 0,000 0,05752358 0,06334267 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,05752358 0,06331329 ! adult behavior GO:0030534 90 56 0,000 0,05752358 0,06328394 ! cartilage development GO:0051216 84 56 0,000 0,05752358 0,06325461 ! mesoderm development GO:0007498 84 57 0,000 0,05852156 0,06432222 ! aging GO:0007568 91 57 0,000 0,05852156 0,06429244 ! nuclear export GO:0051168 85 57 0,000 0,05852156 0,06426269 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,05852156 0,06423296 ! single fertilization GO:0007338 67 57 0,000 0,05852156 0,06420327 ! regulation of cellular component size GO:0032535 90 58 0,000 0,05951854 0,06526686 ! lipid modification GO:0030258 82 58 0,000 0,05951854 0,06523672 ! positive regulation of growth GO:0045927 78 58 0,000 0,05951854 0,0652066 ! DNA damage response, signal transduction GO:0042770 105 58 0,000 0,05951854 0,06517651 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,05951854 0,06514645 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,06051451 0,06620605 ! viral reproductive process GO:0022415 99 59 0,000 0,06051451 0,06617555 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,06051451 0,06614506 ! chromosome segregation GO:0007059 93 59 0,000 0,06051451 0,06611461 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,06051451 0,06608418 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,06051451 0,06605379 ! cell projection assembly GO:0030031 90 59 0,000 0,06051451 0,06602342 ! glucose catabolic process GO:0006007 78 60 0,000 0,06150948 0,06707812 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,06150948 0,06704731 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,06150948 0,06701652 ! response to peptide hormone stimulus GO:0043434 97 60 0,000 0,06150948 0,06698577 ! kidney development GO:0001822 101 60 0,000 0,06150948 0,06695504 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,06150948 0,06692434 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,06250344 0,06797464 ! carbohydrate transport GO:0008643 83 61 0,000 0,06250344 0,0679435 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,06250344 0,06791239 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,0634964 0,06895971 ! amino acid transport GO:0006865 97 62 0,000 0,0634964 0,06892816 ! activation of MAPK activity GO:0000187 95 62 0,000 0,0634964 0,06889664 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,0634964 0,06886515 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,0634964 0,0688337 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,0634964 0,06880226 ! detection of external stimulus GO:0009581 78 62 0,000 0,0634964 0,06877086 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,0634964 0,06873949 ! secondary metabolic process GO:0019748 95 62 0,000 0,0634964 0,06870814 ! gonad development GO:0008406 91 62 0,000 0,0634964 0,06867683 ! exocytosis GO:0006887 91 63 0,000 0,06448836 0,06971794 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,06448836 0,06968619 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,06448836 0,06965447 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,06448836 0,06962278 ! regulation of heart contraction GO:0008016 104 63 0,000 0,06448836 0,06959112 ! developmental maturation GO:0021700 90 63 0,000 0,06448836 0,06955949 ! actin filament organization GO:0007015 107 64 0,000 0,06547932 0,07059628 ! fertilization GO:0009566 79 64 0,000 0,06547932 0,07056422 ! viral reproduction GO:0016032 104 64 0,000 0,06547932 0,07053219 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,06547932 0,07050019 ! amine catabolic process GO:0009310 100 65 0,000 0,06646928 0,0715336 ! camera-type eye development GO:0043010 103 65 0,000 0,06646928 0,07150117 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,06646928 0,07146878 ! regulation of lipase activity GO:0060191 117 65 0,000 0,06646928 0,07143641 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,06646928 0,07140407 ! organelle localization GO:0051640 105 65 0,000 0,06646928 0,07137176 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,06745824 0,0724009 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,06745824 0,07236817 ! sensory perception of smell GO:0007608 81 66 0,000 0,06745824 0,07233547 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,06745824 0,0723028 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,06745824 0,07227015 ! lung development GO:0030324 112 66 0,000 0,06745824 0,07223754 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,06745824 0,07220496 ! B cell activation GO:0042113 119 66 0,000 0,06745824 0,0721724 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,06745824 0,07213988 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 0,000 0,06745824 0,07210738 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,0684462 0,07313049 ! neurotransmitter transport GO:0006836 92 67 0,000 0,0684462 0,07309758 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,0684462 0,0730647 ! appendage morphogenesis GO:0035107 103 67 0,000 0,0684462 0,07303185 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,0684462 0,07299902 ! extracellular matrix organization GO:0030198 117 67 0,000 0,0684462 0,07296623 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,0684462 0,07293346 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! meiosis GO:0007126 110 68 0,000 0,06943316 0,07395193 GO:0051327|M phase of meiotic cell cycle, ! regulation of caspase activity GO:0043281 104 68 0,000 0,06943316 0,07391875 ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,06943316 0,0738856 ! defense response to bacterium GO:0042742 79 68 0,000 0,06943316 0,07385248 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,06943316 0,0738194 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,06943316 0,07378634 ! activation of immune response GO:0002253 93 68 0,000 0,06943316 0,07375331 ! appendage development GO:0048736 108 69 0,000 0,07041913 0,07476716 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,07041913 0,07473372 ! urogenital system development GO:0001655 114 69 0,000 0,07041913 0,07470031 ! meiotic cell cycle GO:0051321 111 69 0,000 0,07041913 0,07466693 ! regulation of endopeptidase activity GO:0052548 106 70 0,000 0,0714041 0,07567751 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 0,000 0,0714041 0,07564372 ! hexose catabolic process GO:0019320 95 70 0,000 0,0714041 0,07560997 ! adaptive immune response GO:0002250 102 70 0,000 0,0714041 0,07557624 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,07238808 0,07658356 ! cell-matrix adhesion GO:0007160 133 71 0,000 0,07238808 0,07654943 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,07238808 0,07651533 ! axon guidance GO:0007411 116 71 0,000 0,07238808 0,07648127 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,07238808 0,07644723 ! regulation of actin cytoskeleton organization GO:0032956 120 72 0,000 0,07337107 0,07745087 ! response to drug GO:0042493 115 72 0,000 0,07337107 0,07741643 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,07337107 0,07738202 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,07337107 0,07734765 ! respiratory system development GO:0060541 123 72 0,000 0,07337107 0,0773133 ! rhythmic process GO:0048511 113 72 0,000 0,07337107 0,07727898 ! learning or memory GO:0007611 132 73 0,000 0,07435307 0,07827854 ! humoral immune response GO:0006959 93 73 0,000 0,07435307 0,07824383 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 0,000 0,07435307 0,07820914 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 0,000 0,07435307 0,07817449 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,07435307 0,07813987 ! acute inflammatory response GO:0002526 107 74 0,000 0,07533407 0,07913579 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,07533407 0,07910077 ! regulation of actin filament-based process GO:0032970 122 74 0,000 0,07533407 0,07906579 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,07533407 0,07903083 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,07533407 0,07899591 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,07533407 0,07896102 ! regulation of Rho protein signal transduction GO:0035023 126 74 0,000 0,07533407 0,07892616 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,07533407 0,07889133 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,07631408 0,07988236 ! regulation of peptidase activity GO:0052547 113 75 0,000 0,07631408 0,07984714 ! inorganic anion transport GO:0015698 109 75 0,000 0,07631408 0,07981195 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,07631408 0,07977679 ! regulation of catabolic process GO:0009894 114 75 0,000 0,07631408 0,07974166 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,07729311 0,08072911 ! phosphoinositide-mediated signaling GO:0048015 122 76 0,000 0,07729311 0,0806936 ! cell-substrate adhesion GO:0031589 141 76 0,000 0,07729311 0,08065811 ! regulation of Ras GTPase activity GO:0032318 125 76 0,000 0,07729311 0,08062266 ! positive regulation of ligase activity GO:0051351 114 76 0,000 0,07729311 0,08058723 ! negative regulation of transport GO:0051051 122 77 0,000 0,07827114 0,08157111 ! response to nutrient GO:0007584 114 77 0,000 0,07827114 0,0815353 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,07827114 0,08149953 ! regulation of blood pressure GO:0008217 119 78 0,000 0,07924819 0,08248068 ! muscle cell differentiation GO:0042692 117 78 0,000 0,07924819 0,08244452 ! amine transport GO:0015837 115 78 0,000 0,07924819 0,0824084 ! antigen processing and presentation GO:0019882 114 78 0,000 0,07924819 0,0823723 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 0,000 0,08022425 0,08335033 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,08022425 0,08331385 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,08119933 0,08428959 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,08119933 0,08425274 ! regulation of DNA binding GO:0051101 130 80 0,000 0,08119933 0,08421591 ! eye development GO:0001654 130 80 0,000 0,08119933 0,08417912 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,08119933 0,08414236 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,08119933 0,08410564 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,08119933 0,08406894 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,08119933 0,08403228 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,08119933 0,08399565 ! blood coagulation GO:0007596 129 81 0,000 0,08217342 0,08496624 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,08217342 0,08492924 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,08217342 0,08489226 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,08217342 0,08485532 ! response to hypoxia GO:0001666 155 81 0,000 0,08217342 0,08481841 ! regulation of protein transport GO:0051223 123 81 0,000 0,08217342 0,08478153 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,08314653 0,08574825 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,08314653 0,085711 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,08314653 0,08567378 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,08314653 0,0856366 ! regulation of ligase activity GO:0051340 129 82 0,000 0,08314653 0,08559944 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,08411866 0,08656269 ! response to oxygen levels GO:0070482 160 83 0,000 0,08411866 0,08652517 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,08411866 0,08648768 ! regulation of lyase activity GO:0051339 147 83 0,000 0,08411866 0,08645023 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,08411866 0,0864128 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,0850898 0,08737261 ! digestion GO:0007586 111 84 0,000 0,0850898 0,08733482 ! regulation of neurological system process GO:0031644 133 84 0,000 0,0850898 0,08729706 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,0850898 0,08725933 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,08605996 0,08821611 ! T cell activation GO:0042110 154 85 0,000 0,08605996 0,08817802 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 0,000 0,08605996 0,08813996 GO:0010498|proteasomal protein catabolic process, ! sex differentiation GO:0007548 126 85 0,000 0,08605996 0,08810194 ! protein import into nucleus GO:0006606 145 85 0,000 0,08605996 0,08806395 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,08605996 0,08802599 ! alcohol catabolic process GO:0046164 119 86 0,000 0,08702915 0,08897896 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,08702915 0,08894064 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,08799735 0,0898914 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,08799735 0,08985272 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,08799735 0,08981407 ! tRNA metabolic process GO:0006399 110 87 0,000 0,08799735 0,08977546 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,08799735 0,08973688 ! gland development GO:0048732 170 87 0,000 0,08799735 0,08969833 ! vitamin metabolic process GO:0006766 117 87 0,000 0,08799735 0,08965982 ! forebrain development GO:0030900 151 87 0,000 0,08799735 0,08962134 ! regulation of membrane potential GO:0042391 144 88 0,000 0,08896458 0,09056754 ! ossification GO:0001503 150 89 0,000 0,08993083 0,09151194 GO:0060348|bone development, ! nucleosome assembly GO:0006334 113 89 0,000 0,08993083 0,09147272 GO:0031497|chromatin assembly, ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,0908961 0,09241493 ! microtubule cytoskeleton organization GO:0000226 133 90 0,000 0,0908961 0,09237535 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,0908961 0,09233581 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,0908961 0,0922963 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,0908961 0,09225682 ! regulation of GTPase activity GO:0043087 149 90 0,000 0,0908961 0,09221738 ! nuclear import GO:0051170 153 90 0,000 0,0908961 0,09217797 ! regulation of protein localization GO:0032880 141 90 0,000 0,0908961 0,09213859 ! detection of stimulus GO:0051606 123 91 0,000 0,0918604 0,09307631 ! protein localization in nucleus GO:0034504 161 92 0,000 0,09282372 0,09401225 ! sterol metabolic process GO:0016125 136 92 0,000 0,09282372 0,09397214 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,09378608 0,09490591 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,09378608 0,09486545 ! rRNA processing GO:0006364 124 93 0,000 0,09378608 0,09482504 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,09378608 0,09478465 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,09378608 0,0947443 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,09378608 0,09470398 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,09378608 0,0946637 ! leukocyte differentiation GO:0002521 165 94 0,000 0,09474745 0,09559341 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,09474745 0,09555279 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,09474745 0,0955122 ! rRNA metabolic process GO:0016072 125 94 0,000 0,09474745 0,09547164 ! regulation of cell adhesion GO:0030155 187 94 0,000 0,09474745 0,09543112 ! hormone metabolic process GO:0042445 135 94 0,000 0,09474745 0,09539063 ! protein processing GO:0016485 127 94 0,000 0,09474745 0,09535017 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,09570786 0,09627586 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,09570786 0,09623507 ! ATP metabolic process GO:0046034 150 96 0,000 0,0966673 0,09715862 ! nucleosome organization GO:0034728 126 96 0,000 0,0966673 0,09711748 ! female pregnancy GO:0007565 148 96 0,000 0,0966673 0,09707639 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,09762577 0,09799744 ! reproductive developmental process GO:0003006 149 97 0,000 0,09762577 0,097956 ! response to virus GO:0009615 141 98 0,000 0,09858326 0,09887493 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,09858326 0,09883316 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,09858326 0,09879142 ! regulation of T cell activation GO:0050863 155 98 0,000 0,09858326 0,09874972 ! regulation of binding GO:0051098 164 99 0,000 0,0995398 0,0996658 ! cell fate commitment GO:0045165 165 99 0,000 0,0995398 0,09962376 ! positive regulation of immune response GO:0050778 143 99 0,000 0,0995398 0,09958176 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,10049536 0,10049536