pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/2580-3-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! thymus development GO:0048538 6 6 1,000 6,331E-06 0,01166884 ! T cell homeostasis GO:0043029 8 8 1,000 1,181E-05 0,01088458 ! lymphocyte homeostasis GO:0002260 10 10 1,000 1,897E-05 0,01165527 ! leukocyte homeostasis GO:0001776 15 15 1,000 4,42E-05 0,02036705 ! myeloid leukocyte activation GO:0002274 18 17 1,000 5,722E-05 0,02109186 ! response to metal ion GO:0010038 34 34 1,000 2,349E-04 0,07214511 ! response to inorganic substance GO:0010035 36 36 1,000 2,636E-04 0,06940402 ! homeostasis of number of cells GO:0048872 44 43 1,000 3,771E-04 0,08686671 ! in utero embryonic development GO:0001701 55 55 1,000 6,179E-04 0,12653736 ! growth GO:0040007 70 70 1,000 1,001E-03 0,184395 ! rRNA transcription GO:0009303 5 5 0,000 3,629E-03 0,60810571 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 3,629E-03 0,55743023 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 3,629E-03 0,51455098 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 3,629E-03 0,47779734 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 3,629E-03 0,44594419 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 3,629E-03 0,41807267 ! reproductive cellular process GO:0048610 5 5 0,000 3,629E-03 0,39348016 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 3,629E-03 0,37162016 ! negative regulation of blood pressure GO:0045776 6 5 0,000 3,629E-03 0,3520612 ! prostate gland development GO:0030850 5 5 0,000 3,629E-03 0,33445814 ! metencephalon development GO:0022037 5 5 0,000 3,629E-03 0,31853156 ! water transport GO:0006833 5 5 0,000 3,629E-03 0,30405285 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 3,629E-03 0,29083316 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 3,629E-03 0,27871512 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 3,629E-03 0,26756651 ! glycerol metabolic process GO:0006071 5 5 0,000 3,629E-03 0,25727549 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 3,629E-03 0,24774677 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 3,629E-03 0,23889867 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 3,629E-03 0,23066079 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 3,629E-03 0,22297209 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 3,629E-03 0,21577944 ! filopodium assembly GO:0046847 7 5 0,000 3,629E-03 0,20903634 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 3,629E-03 0,2027019 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 3,629E-03 0,19674008 ! GTP metabolic process GO:0046039 5 5 0,000 3,629E-03 0,19111894 ! establishment of tissue polarity GO:0007164 5 5 0,000 3,629E-03 0,18581008 ! mRNA stabilization GO:0048255 5 5 0,000 3,629E-03 0,18078818 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 3,629E-03 0,1760306 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 3,629E-03 0,17151699 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 3,629E-03 0,16722907 ! social behavior GO:0035176 5 5 0,000 3,629E-03 0,16315031 ! macrophage chemotaxis GO:0048246 6 5 0,000 3,629E-03 0,15926578 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 3,629E-03 0,15556193 ! memory GO:0007613 5 5 0,000 3,629E-03 0,15202643 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 3,629E-03 0,14864806 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 3,629E-03 0,14541658 ! membrane hyperpolarization GO:0060081 5 5 0,000 3,629E-03 0,14232261 ! response to lipid GO:0033993 5 5 0,000 3,629E-03 0,13935756 ! erythrocyte maturation GO:0043249 5 5 0,000 3,629E-03 0,13651353 ! hippocampus development GO:0021766 6 5 0,000 3,629E-03 0,13378326 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 3,629E-03 0,13116005 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 3,629E-03 0,12863775 ! middle ear morphogenesis GO:0042474 5 5 0,000 3,629E-03 0,12621062 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 3,629E-03 0,12387339 ! mechanosensory behavior GO:0007638 5 5 0,000 3,629E-03 0,12162114 ! heart looping GO:0001947 5 5 0,000 3,629E-03 0,11944934 ! negative regulation of endocytosis GO:0045806 5 5 0,000 3,629E-03 0,11735373 ! response to interferon-gamma GO:0034341 5 5 0,000 3,629E-03 0,11533039 ! pseudouridine synthesis GO:0001522 5 5 0,000 3,629E-03 0,11337564 ! endocrine pancreas development GO:0031018 5 5 0,000 3,629E-03 0,11148605 ! pH reduction GO:0045851 5 5 0,000 3,629E-03 0,10965841 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 3,629E-03 0,10788972 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 3,629E-03 0,10617719 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 3,629E-03 0,10451817 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 3,629E-03 0,1029102 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 3,629E-03 0,10135095 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 3,629E-03 0,09983825 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 3,629E-03 0,09837004 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 3,629E-03 0,09694439 ! adrenal gland development GO:0030325 5 5 0,000 3,629E-03 0,09555947 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 3,629E-03 0,09421356 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 3,629E-03 0,09290504 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 3,629E-03 0,09163237 ! astrocyte differentiation GO:0048708 5 5 0,000 3,629E-03 0,09039409 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 3,629E-03 0,08918884 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 3,629E-03 0,0880153 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 3,629E-03 0,08687224 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 3,629E-03 0,0857585 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 3,629E-03 0,08467295 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 3,629E-03 0,08361453 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 3,629E-03 0,08258226 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 3,629E-03 0,08157516 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 3,629E-03 0,08059232 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 3,629E-03 0,07963289 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 3,629E-03 0,07869603 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 3,629E-03 0,07778096 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 3,629E-03 0,07688693 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 3,629E-03 0,07601321 ! response to ATP GO:0033198 5 5 0,000 3,629E-03 0,07515913 ! regulation of type I interferon production GO:0032479 5 5 0,000 3,629E-03 0,07432403 ! regulation of appetite GO:0032098 5 5 0,000 3,629E-03 0,07350728 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 3,629E-03 0,07270829 ! paraxial mesoderm development GO:0048339 5 5 0,000 3,629E-03 0,07192648 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 3,629E-03 0,07116131 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 3,629E-03 0,07041224 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 3,629E-03 0,06967878 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 3,629E-03 0,06896044 ! receptor clustering GO:0043113 5 5 0,000 3,629E-03 0,06825676 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 3,629E-03 0,0675673 ! fear response GO:0042596 5 5 0,000 3,629E-03 0,06689163 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 3,629E-03 0,06622933 ! lens development in camera-type eye GO:0002088 5 5 0,000 3,629E-03 0,06558003 ! retinol metabolic process GO:0042572 5 5 0,000 3,629E-03 0,06494333 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 3,629E-03 0,06431887 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 3,629E-03 0,06370631 ! positive regulation of exocytosis GO:0045921 6 5 0,000 3,629E-03 0,06310531 ! parturition GO:0007567 5 5 0,000 3,629E-03 0,06251554 ! cellular glucose homeostasis GO:0001678 5 5 0,000 3,629E-03 0,06193669 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 3,629E-03 0,06136847 ! Schwann cell differentiation GO:0014037 5 5 0,000 3,629E-03 0,06081057 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 3,629E-03 0,06026273 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 3,629E-03 0,05972467 ! protein heterooligomerization GO:0051291 5 5 0,000 3,629E-03 0,05919613 ! regulation of gliogenesis GO:0014013 5 5 0,000 3,629E-03 0,05867687 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 3,629E-03 0,05816663 ! response to UV-B GO:0010224 5 5 0,000 3,629E-03 0,0576652 ! oligodendrocyte development GO:0014003 5 5 0,000 3,629E-03 0,05717233 ! hyaluronan metabolic process GO:0030212 5 5 0,000 3,629E-03 0,05668782 ! activated T cell proliferation GO:0050798 5 5 0,000 3,629E-03 0,05621145 ! interaction with symbiont GO:0051702 5 5 0,000 3,629E-03 0,05574302 ! cellular extravasation GO:0045123 5 5 0,000 3,629E-03 0,05528234 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 3,629E-03 0,0548292 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 3,629E-03 0,05438344 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 3,629E-03 0,05394486 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 3,629E-03 0,0535133 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 3,629E-03 0,05308859 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 3,629E-03 0,05267057 ! response to amine stimulus GO:0014075 5 5 0,000 3,629E-03 0,05225908 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 3,629E-03 0,05185398 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 3,629E-03 0,0514551 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 3,629E-03 0,05106231 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 3,629E-03 0,05067548 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 3,629E-03 0,05029446 ! neuron recognition GO:0008038 5 5 0,000 3,629E-03 0,04991913 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 3,629E-03 0,04954935 ! decidualization GO:0046697 5 5 0,000 3,629E-03 0,04918502 ! hair follicle maturation GO:0048820 5 5 0,000 3,629E-03 0,04882601 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 3,629E-03 0,04847219 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 3,629E-03 0,04812347 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 3,629E-03 0,04777973 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 3,629E-03 0,04744087 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 3,629E-03 0,04710678 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 3,629E-03 0,04677736 ! postreplication repair GO:0006301 5 5 0,000 3,629E-03 0,04645252 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 3,629E-03 0,04613216 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 3,629E-03 0,04581618 ! histone methylation GO:0016571 5 5 0,000 3,629E-03 0,04550451 ! DNA methylation GO:0006306 5 5 0,000 3,629E-03 0,04519705 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 3,629E-03 0,04489371 ! T cell lineage commitment GO:0002360 5 5 0,000 3,629E-03 0,04459442 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 3,629E-03 0,04429909 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 3,629E-03 0,04400765 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 3,629E-03 0,04372002 ! intracellular cholesterol transport GO:0032367 5 5 0,000 3,629E-03 0,04343612 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 3,629E-03 0,04315589 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 3,629E-03 0,04287925 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 3,629E-03 0,04260613 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 3,629E-03 0,04233647 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 3,629E-03 0,04207021 ! sterol catabolic process GO:0016127 5 5 0,000 3,629E-03 0,04180727 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 3,629E-03 0,04154759 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 3,629E-03 0,04129113 ! detection of biotic stimulus GO:0009595 5 5 0,000 3,629E-03 0,04103781 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 3,629E-03 0,04078758 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 3,629E-03 0,04054038 ! zymogen activation GO:0031638 5 5 0,000 3,629E-03 0,04029616 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 3,629E-03 0,04005487 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 3,629E-03 0,03981645 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 3,629E-03 0,03958084 ! peptidyl-lysine modification GO:0018205 5 5 0,000 3,629E-03 0,03934802 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 3,629E-03 0,03911791 ! peptidyl-histidine modification GO:0018202 5 5 0,000 3,629E-03 0,03889048 ! nucleosome positioning GO:0016584 5 5 0,000 3,629E-03 0,03866568 ! regulation of isotype switching GO:0045191 5 5 0,000 3,629E-03 0,03844346 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 3,629E-03 0,03822379 ! negative regulation of neurological system process GO:0031645 5 5 0,000 3,629E-03 0,03800661 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 3,629E-03 0,03779188 ! glutathione biosynthetic process GO:0006750 5 5 0,000 3,629E-03 0,03757957 ! NADPH regeneration GO:0006740 5 5 0,000 3,629E-03 0,03736962 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 3,629E-03 0,03716202 ! positive regulation of epidermis development GO:0045684 5 5 0,000 3,629E-03 0,0369567 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 3,629E-03 0,03675364 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 3,629E-03 0,0365528 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 3,629E-03 0,03635415 ! sarcomere organization GO:0045214 5 5 0,000 3,629E-03 0,03615764 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 3,629E-03 0,03596324 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 3,629E-03 0,03577092 ! negative regulation of glucose transport GO:0010829 5 5 0,000 3,629E-03 0,03558065 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 3,629E-03 0,0353924 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 3,629E-03 0,03520612 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 3,629E-03 0,03502179 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 3,629E-03 0,03483939 ! spleen development GO:0048536 5 5 0,000 3,629E-03 0,03465887 ! male genitalia development GO:0030539 5 5 0,000 3,629E-03 0,03448022 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 3,629E-03 0,0343034 ! quaternary ammonium group transport GO:0015697 5 5 0,000 3,629E-03 0,03412838 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 3,629E-03 0,03395514 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 3,629E-03 0,03378365 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 3,629E-03 0,03361388 ! removal of superoxide radicals GO:0019430 6 5 0,000 3,629E-03 0,03344581 ! myeloid cell homeostasis GO:0002262 5 5 0,000 3,629E-03 0,03327942 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 3,629E-03 0,03311467 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 3,629E-03 0,03295154 ! ATP catabolic process GO:0006200 5 5 0,000 3,629E-03 0,03279001 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 3,629E-03 0,03263006 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 3,629E-03 0,03247166 ! blastocyst formation GO:0001825 5 5 0,000 3,629E-03 0,0323148 ! regulation of fibrinolysis GO:0051917 5 5 0,000 3,629E-03 0,03215944 ! embryonic gut development GO:0048566 5 5 0,000 3,629E-03 0,03200556 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 3,629E-03 0,03185316 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 3,629E-03 0,03170219 ! activation of innate immune response GO:0002218 5 5 0,000 3,629E-03 0,03155265 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 3,629E-03 0,03140452 ! catecholamine transport GO:0051937 5 5 0,000 3,629E-03 0,03125777 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 3,629E-03 0,03111239 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 3,629E-03 0,03096835 ! muscle adaptation GO:0043500 5 5 0,000 3,629E-03 0,03082563 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 3,629E-03 0,03068423 ! embryonic heart tube development GO:0035050 5 5 0,000 3,629E-03 0,03054412 ! cardiac cell differentiation GO:0035051 6 5 0,000 3,629E-03 0,03040529 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 3,629E-03 0,0302677 ! defense response to fungus GO:0050832 5 5 0,000 3,629E-03 0,03013136 ! lysogeny GO:0030069 5 5 0,000 3,629E-03 0,02999625 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 3,629E-03 0,02986233 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 3,629E-03 0,02972961 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 3,629E-03 0,02959807 ! response to nicotine GO:0035094 5 5 0,000 3,629E-03 0,02946768 ! establishment of cell polarity GO:0030010 5 5 0,000 3,629E-03 0,02933843 ! mitochondrion localization GO:0051646 5 5 0,000 3,629E-03 0,02921032 ! nucleus localization GO:0051647 5 5 0,000 3,629E-03 0,02908332 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 3,629E-03 0,02895741 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 4,354E-03 0,03458906 ! axon extension GO:0048675 7 6 0,000 4,354E-03 0,03444061 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 4,354E-03 0,03429343 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 4,354E-03 0,0341475 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 4,354E-03 0,0340028 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 4,354E-03 0,03385933 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 4,354E-03 0,03371707 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 4,354E-03 0,03357599 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 4,354E-03 0,03343609 ! virus-host interaction GO:0019048 6 6 0,000 4,354E-03 0,03329735 ! regulation of S phase GO:0033261 6 6 0,000 4,354E-03 0,03315976 ! myotube differentiation GO:0014902 6 6 0,000 4,354E-03 0,0330233 ! regulation of B cell proliferation GO:0030888 6 6 0,000 4,354E-03 0,03288796 ! bone remodeling GO:0046849 6 6 0,000 4,354E-03 0,03275372 ! N-glycan processing GO:0006491 6 6 0,000 4,354E-03 0,03262058 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 4,354E-03 0,03248851 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 4,354E-03 0,03235751 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 4,354E-03 0,03222756 ! retina development in camera-type eye GO:0060041 6 6 0,000 4,354E-03 0,03209865 ! RNA methylation GO:0001510 6 6 0,000 4,354E-03 0,03197076 ! cartilage condensation GO:0001502 7 6 0,000 4,354E-03 0,0318439 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 4,354E-03 0,03171803 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 4,354E-03 0,03159316 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 4,354E-03 0,03146926 ! artery development GO:0060840 6 6 0,000 4,354E-03 0,03134633 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 4,354E-03 0,03122436 ! bile acid metabolic process GO:0008206 6 6 0,000 4,354E-03 0,03110334 ! androgen metabolic process GO:0008209 6 6 0,000 4,354E-03 0,03098325 ! estrogen metabolic process GO:0008210 6 6 0,000 4,354E-03 0,03086408 ! limbic system development GO:0021761 7 6 0,000 4,354E-03 0,03074583 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 4,354E-03 0,03062848 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 4,354E-03 0,03051202 ! positive regulation of heart contraction GO:0045823 6 6 0,000 4,354E-03 0,03039645 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 4,354E-03 0,03028174 ! pathogenesis GO:0009405 6 6 0,000 4,354E-03 0,0301679 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 4,354E-03 0,03005491 ! positive regulation of cell growth GO:0030307 6 6 0,000 4,354E-03 0,02994277 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 4,354E-03 0,02983146 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 4,354E-03 0,02972097 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 4,354E-03 0,0296113 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 4,354E-03 0,02950243 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 4,354E-03 0,02939436 ! arginine metabolic process GO:0006525 6 6 0,000 4,354E-03 0,02928709 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 4,354E-03 0,02918059 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 4,354E-03 0,02907486 ! glutamate catabolic process GO:0006538 7 6 0,000 4,354E-03 0,0289699 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 4,354E-03 0,02886569 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 4,354E-03 0,02876223 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 4,354E-03 0,02865951 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 4,354E-03 0,02855751 ! ER overload response GO:0006983 6 6 0,000 4,354E-03 0,02845625 ! V(D)J recombination GO:0033151 6 6 0,000 4,354E-03 0,02835569 ! focal adhesion formation GO:0048041 7 6 0,000 4,354E-03 0,02825585 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 4,354E-03 0,02815671 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 4,354E-03 0,02805826 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 4,354E-03 0,02796049 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 4,354E-03 0,02786341 ! regulation of heart rate GO:0002027 6 6 0,000 4,354E-03 0,027767 ! lipid digestion GO:0044241 6 6 0,000 4,354E-03 0,02767125 ! asymmetric protein localization GO:0008105 6 6 0,000 4,354E-03 0,02757616 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 4,354E-03 0,02748172 ! phagocytosis, engulfment GO:0006911 6 6 0,000 4,354E-03 0,02738792 ! Rac protein signal transduction GO:0016601 6 6 0,000 4,354E-03 0,02729477 ! regulation of vascular permeability GO:0043114 6 6 0,000 4,354E-03 0,02720224 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 4,354E-03 0,02711034 ! ruffle organization GO:0031529 6 6 0,000 4,354E-03 0,02701906 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 4,354E-03 0,02692839 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 4,354E-03 0,02683833 ! retinoic acid metabolic process GO:0042573 6 6 0,000 4,354E-03 0,02674887 ! neutral amino acid transport GO:0015804 6 6 0,000 4,354E-03 0,02666001 ! L-amino acid transport GO:0015807 6 6 0,000 4,354E-03 0,02657173 ! bone mineralization GO:0030282 6 6 0,000 4,354E-03 0,02648403 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 4,354E-03 0,02639691 ! negative regulation of ossification GO:0030279 6 6 0,000 4,354E-03 0,02631037 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 4,354E-03 0,02622438 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 4,354E-03 0,02613896 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 4,354E-03 0,0260541 ! purine base biosynthetic process GO:0009113 6 6 0,000 4,354E-03 0,02596978 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 4,354E-03 0,02588601 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 4,354E-03 0,02580277 ! regulation of phagocytosis GO:0050764 6 6 0,000 4,354E-03 0,02572007 ! regulation of organ growth GO:0046620 6 6 0,000 4,354E-03 0,0256379 ! regulation of circadian rhythm GO:0042752 6 6 0,000 4,354E-03 0,02555625 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 4,354E-03 0,02547512 ! response to dsRNA GO:0043331 6 6 0,000 4,354E-03 0,0253945 ! DNA unwinding during replication GO:0006268 6 6 0,000 4,354E-03 0,02531439 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 4,354E-03 0,02523478 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 4,354E-03 0,02515568 ! genitalia development GO:0048806 6 6 0,000 4,354E-03 0,02507707 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 4,354E-03 0,02499895 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 4,354E-03 0,02492131 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 4,354E-03 0,02484415 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 4,354E-03 0,02476747 ! multicellular organismal aging GO:0010259 6 6 0,000 4,354E-03 0,02469127 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 4,354E-03 0,02461553 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 4,354E-03 0,02454025 ! erythrocyte development GO:0048821 6 6 0,000 4,354E-03 0,02446543 ! renal water homeostasis GO:0003091 6 6 0,000 4,354E-03 0,02439107 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 4,354E-03 0,02431716 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 4,354E-03 0,02424369 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 4,354E-03 0,02417067 ! ribosome assembly GO:0042255 6 6 0,000 4,354E-03 0,02409808 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 4,354E-03 0,02402593 ! diencephalon development GO:0021536 6 6 0,000 4,354E-03 0,02395421 ! fucose catabolic process GO:0019317 6 6 0,000 4,354E-03 0,02388292 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 4,354E-03 0,02381205 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 4,354E-03 0,0237416 ! regulation of lipid transport GO:0032368 6 6 0,000 4,354E-03 0,02367157 ! regulation of cell division GO:0051302 6 6 0,000 4,354E-03 0,02360195 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 4,354E-03 0,02353273 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 4,354E-03 0,02346392 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 4,354E-03 0,02339551 ! salivary gland morphogenesis GO:0007435 6 6 0,000 4,354E-03 0,0233275 ! neuroblast proliferation GO:0007405 6 6 0,000 4,354E-03 0,02325989 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 4,354E-03 0,02319266 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 4,354E-03 0,02312583 ! regulation of glucose transport GO:0010827 6 6 0,000 4,354E-03 0,02305937 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 4,354E-03 0,0229933 ! methionine biosynthetic process GO:0009086 6 6 0,000 4,354E-03 0,0229276 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 4,354E-03 0,02286228 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 4,354E-03 0,02279733 ! lymph node development GO:0048535 6 6 0,000 4,354E-03 0,02273275 ! organic cation transport GO:0015695 6 6 0,000 4,354E-03 0,02266854 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 4,354E-03 0,02260468 ! regulation of RNA splicing GO:0043484 6 6 0,000 4,354E-03 0,02254118 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 4,354E-03 0,02247804 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 4,354E-03 0,02241526 ! sperm-egg recognition GO:0035036 7 6 0,000 4,354E-03 0,02235282 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 4,354E-03 0,02229073 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 4,354E-03 0,02222898 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 4,354E-03 0,02216757 ! alditol metabolic process GO:0019400 6 6 0,000 4,354E-03 0,02210651 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 4,354E-03 0,02204577 ! regulation of amino acid transport GO:0051955 6 6 0,000 4,354E-03 0,02198537 ! maternal placenta development GO:0001893 6 6 0,000 4,354E-03 0,0219253 ! regulation of embryonic development GO:0045995 6 6 0,000 4,354E-03 0,02186556 ! negative regulation of immune effector process GO:0002698 6 6 0,000 4,354E-03 0,02180615 ! localization within membrane GO:0051668 6 6 0,000 4,354E-03 0,02174705 ! respiratory burst GO:0045730 7 7 0,000 5,078E-03 0,02529563 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 5,078E-03 0,02522745 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 5,078E-03 0,02515963 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 5,078E-03 0,02509218 ! positive regulation of blood pressure GO:0045777 7 7 0,000 5,078E-03 0,02502509 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 5,078E-03 0,02495836 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 5,078E-03 0,02489198 ! regulation of chemokine production GO:0032642 7 7 0,000 5,078E-03 0,02482595 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 5,078E-03 0,02476027 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 5,078E-03 0,02469494 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 5,078E-03 0,02462996 ! cellular protein complex disassembly GO:0043624 8 7 0,000 5,078E-03 0,02456531 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 5,078E-03 0,024501 ! gene silencing by RNA GO:0031047 7 7 0,000 5,078E-03 0,02443703 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 5,078E-03 0,02437339 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 5,078E-03 0,02431009 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 5,078E-03 0,02424711 ! keratinocyte proliferation GO:0043616 7 7 0,000 5,078E-03 0,02418445 ! axis specification GO:0009798 7 7 0,000 5,078E-03 0,02412212 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 5,078E-03 0,02406011 ! visual behavior GO:0007632 7 7 0,000 5,078E-03 0,02399842 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 5,078E-03 0,02393704 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 5,078E-03 0,02387598 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 5,078E-03 0,02381522 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 5,078E-03 0,02375478 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 5,078E-03 0,02369464 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 5,078E-03 0,02363481 ! endothelial cell differentiation GO:0045446 7 7 0,000 5,078E-03 0,02357527 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 5,078E-03 0,02351604 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 5,078E-03 0,0234571 ! digestive system development GO:0055123 7 7 0,000 5,078E-03 0,02339846 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 5,078E-03 0,02334011 ! regulation of exit from mitosis GO:0007096 7 7 0,000 5,078E-03 0,02328205 ! protein targeting to ER GO:0045047 8 7 0,000 5,078E-03 0,02322428 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 5,078E-03 0,02316679 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 5,078E-03 0,02310959 ! endoderm development GO:0007492 7 7 0,000 5,078E-03 0,02305267 ! regulation of defense response to virus GO:0050688 7 7 0,000 5,078E-03 0,02299603 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 5,078E-03 0,02293966 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 5,078E-03 0,02288358 ! response to hexose stimulus GO:0009746 7 7 0,000 5,078E-03 0,02282776 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 5,078E-03 0,02277222 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 5,078E-03 0,02271695 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 5,078E-03 0,02266194 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 5,078E-03 0,02260721 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 5,078E-03 0,02255273 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 5,078E-03 0,02249852 ! complement activation, alternative pathway GO:0006957 7 7 0,000 5,078E-03 0,02244456 ! arachidonic acid secretion GO:0050482 7 7 0,000 5,078E-03 0,02239087 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 5,078E-03 0,02233743 ! response to X-ray GO:0010165 7 7 0,000 5,078E-03 0,02228425 ! regulation of intracellular pH GO:0051453 7 7 0,000 5,078E-03 0,02223131 ! UV protection GO:0009650 7 7 0,000 5,078E-03 0,02217863 ! DNA integration GO:0015074 7 7 0,000 5,078E-03 0,0221262 ! myofibril assembly GO:0030239 7 7 0,000 5,078E-03 0,02207402 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 5,078E-03 0,02202208 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 5,078E-03 0,02197038 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 5,078E-03 0,02191893 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 5,078E-03 0,02186772 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 5,078E-03 0,02181674 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 5,078E-03 0,02176601 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 5,078E-03 0,02171551 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 5,078E-03 0,02166524 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 5,078E-03 0,0216152 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 5,078E-03 0,0215654 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 5,078E-03 0,02151582 ! axon cargo transport GO:0008088 7 7 0,000 5,078E-03 0,02146648 ! eating behavior GO:0042755 7 7 0,000 5,078E-03 0,02141735 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 5,078E-03 0,02136845 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 5,078E-03 0,02131978 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 5,078E-03 0,02127133 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 5,078E-03 0,02122309 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 5,078E-03 0,02117508 ! cranial nerve development GO:0021545 7 7 0,000 5,078E-03 0,02112728 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 5,078E-03 0,02107969 ! induction of an organ GO:0001759 7 7 0,000 5,078E-03 0,02103232 ! leukocyte activation during immune response GO:0002366 7 7 0,000 5,078E-03 0,02098516 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 5,078E-03 0,02093822 ! autonomic nervous system development GO:0048483 7 7 0,000 5,078E-03 0,02089148 ! intracellular lipid transport GO:0032365 7 7 0,000 5,078E-03 0,02084495 ! detection of chemical stimulus GO:0009593 8 7 0,000 5,078E-03 0,02079863 ! platelet activation GO:0030168 8 7 0,000 5,078E-03 0,02075251 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 5,078E-03 0,0207066 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 5,078E-03 0,02066089 ! natural killer cell activation GO:0030101 7 7 0,000 5,078E-03 0,02061538 ! response to gamma radiation GO:0010332 8 7 0,000 5,078E-03 0,02057007 ! NADP metabolic process GO:0006739 7 7 0,000 5,078E-03 0,02052496 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 5,078E-03 0,02048005 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 5,078E-03 0,02043533 ! ubiquinone metabolic process GO:0006743 7 7 0,000 5,078E-03 0,02039081 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 5,078E-03 0,02034649 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 5,078E-03 0,02030235 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 5,078E-03 0,02025841 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 5,078E-03 0,02021465 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 5,078E-03 0,02017108 ! regulation of ATPase activity GO:0043462 7 7 0,000 5,078E-03 0,02012771 ! cell-cell recognition GO:0009988 8 7 0,000 5,078E-03 0,02008451 ! hormone catabolic process GO:0042447 7 7 0,000 5,078E-03 0,02004151 ! dopamine metabolic process GO:0042417 7 7 0,000 5,078E-03 0,01999868 ! cAMP biosynthetic process GO:0006171 7 7 0,000 5,078E-03 0,01995604 ! oxygen transport GO:0015671 7 7 0,000 5,078E-03 0,01991358 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 5,078E-03 0,0198713 ! regulation of mRNA stability GO:0043488 7 7 0,000 5,078E-03 0,0198292 ! biogenic amine catabolic process GO:0042402 7 7 0,000 5,078E-03 0,01978728 ! regulation of axon extension GO:0030516 7 7 0,000 5,078E-03 0,01974553 ! cell killing GO:0001906 7 7 0,000 5,078E-03 0,01970396 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 5,078E-03 0,01966257 ! adult feeding behavior GO:0008343 7 7 0,000 5,078E-03 0,01962135 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 5,078E-03 0,0195803 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 5,078E-03 0,01953942 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 5,078E-03 0,01949872 ! negative regulation of T cell activation GO:0050868 7 7 0,000 5,078E-03 0,01945818 ! response to cold GO:0009409 7 7 0,000 5,078E-03 0,01941781 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 5,802E-03 0,0221394 ! negative regulation of muscle development GO:0048635 8 8 0,000 5,802E-03 0,02209365 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 5,802E-03 0,0220481 ! positive regulation of translation GO:0045727 8 8 0,000 5,802E-03 0,02200273 ! positive regulation of cell killing GO:0031343 8 8 0,000 5,802E-03 0,02195755 ! superoxide anion generation GO:0042554 8 8 0,000 5,802E-03 0,02191256 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 5,802E-03 0,02186775 ! cGMP metabolic process GO:0046068 8 8 0,000 5,802E-03 0,02182312 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 5,802E-03 0,02177867 ! 'de novo' protein folding GO:0006458 8 8 0,000 5,802E-03 0,02173441 ! dicarboxylic acid transport GO:0006835 8 8 0,000 5,802E-03 0,02169032 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 5,802E-03 0,02164641 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 5,802E-03 0,02160268 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 5,802E-03 0,02155913 ! zinc ion transport GO:0006829 8 8 0,000 5,802E-03 0,02151575 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 5,802E-03 0,02147255 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 5,802E-03 0,02142952 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 5,802E-03 0,02138666 ! cardiac muscle contraction GO:0060048 8 8 0,000 5,802E-03 0,02134397 ! lipid localization GO:0010876 8 8 0,000 5,802E-03 0,02130145 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 5,802E-03 0,0212591 ! response to cAMP GO:0051591 8 8 0,000 5,802E-03 0,02121692 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 5,802E-03 0,02117491 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 5,802E-03 0,02113306 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 5,802E-03 0,02109138 ! negative regulation of ion transport GO:0043271 8 8 0,000 5,802E-03 0,02104986 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 5,802E-03 0,0210085 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 5,802E-03 0,02096731 ! sensory perception of taste GO:0050909 8 8 0,000 5,802E-03 0,02092628 ! organelle fusion GO:0048284 8 8 0,000 5,802E-03 0,02088541 ! pancreas development GO:0031016 8 8 0,000 5,802E-03 0,02084469 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 5,802E-03 0,02080414 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 5,802E-03 0,02076374 ! negative regulation of proteolysis GO:0045861 8 8 0,000 5,802E-03 0,0207235 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 5,802E-03 0,02068342 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 5,802E-03 0,02064349 ! sperm motility GO:0030317 8 8 0,000 5,802E-03 0,02060372 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 5,802E-03 0,02056409 ! DNA duplex unwinding GO:0032508 8 8 0,000 5,802E-03 0,02052462 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 5,802E-03 0,0204853 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 5,802E-03 0,02044613 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 5,802E-03 0,02040711 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 5,802E-03 0,02036824 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 5,802E-03 0,02032952 ! Golgi organization GO:0007030 8 8 0,000 5,802E-03 0,02029095 ! cell-cell junction assembly GO:0007043 8 8 0,000 5,802E-03 0,02025252 ! regulation of stress fiber formation GO:0051492 9 8 0,000 5,802E-03 0,02021423 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 5,802E-03 0,02017609 ! fructose metabolic process GO:0006000 8 8 0,000 5,802E-03 0,02013809 ! mannose metabolic process GO:0006013 9 8 0,000 5,802E-03 0,02010024 ! NAD metabolic process GO:0019674 8 8 0,000 5,802E-03 0,02006253 ! sex determination GO:0007530 8 8 0,000 5,802E-03 0,02002496 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 5,802E-03 0,01998753 ! plasma membrane fusion GO:0045026 8 8 0,000 5,802E-03 0,01995024 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 5,802E-03 0,01991309 ! response to fungus GO:0009620 8 8 0,000 5,802E-03 0,01987607 ! stem cell differentiation GO:0048863 8 8 0,000 5,802E-03 0,0198392 ! alpha-beta T cell activation GO:0046631 8 8 0,000 5,802E-03 0,01980246 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 5,802E-03 0,01976586 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 5,802E-03 0,01972939 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 5,802E-03 0,01969305 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 5,802E-03 0,01965685 ! regulation of vasodilation GO:0042312 8 8 0,000 5,802E-03 0,01962079 ! vasoconstriction GO:0042310 8 8 0,000 5,802E-03 0,01958485 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 5,802E-03 0,01954905 ! muscle cell development GO:0055001 8 8 0,000 5,802E-03 0,01951337 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 5,802E-03 0,01947783 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 5,802E-03 0,01944241 ! sensory perception of pain GO:0019233 8 8 0,000 5,802E-03 0,01940713 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 5,802E-03 0,01937197 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 5,802E-03 0,01933694 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 5,802E-03 0,01930204 ! chromatin silencing GO:0006342 8 8 0,000 5,802E-03 0,01926726 ! tissue regeneration GO:0042246 8 8 0,000 5,802E-03 0,0192326 ! salivary gland development GO:0007431 8 8 0,000 5,802E-03 0,01919808 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 5,802E-03 0,01916367 ! peptide biosynthetic process GO:0043043 9 8 0,000 5,802E-03 0,01912939 ! peptidyl-serine modification GO:0018209 8 8 0,000 5,802E-03 0,01909523 ! water homeostasis GO:0030104 8 8 0,000 5,802E-03 0,01906119 ! cofactor transport GO:0051181 8 8 0,000 5,802E-03 0,01902727 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 5,802E-03 0,01899348 ! acid secretion GO:0046717 8 8 0,000 5,802E-03 0,0189598 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 5,802E-03 0,01892624 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 5,802E-03 0,01889281 ! protein-chromophore linkage GO:0018298 9 8 0,000 5,802E-03 0,01885949 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 5,802E-03 0,01882628 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 5,802E-03 0,0187932 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 5,802E-03 0,01876022 ! regulation of RNA stability GO:0043487 8 8 0,000 5,802E-03 0,01872737 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 5,802E-03 0,01869463 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 5,802E-03 0,018662 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 5,802E-03 0,01862949 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 5,802E-03 0,01859709 ! regulation of organic acid transport GO:0032890 8 8 0,000 5,802E-03 0,01856481 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 5,802E-03 0,01853263 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 5,802E-03 0,01850057 ! regulation of multi-organism process GO:0043900 8 8 0,000 5,802E-03 0,01846862 ! positive regulation of amine transport GO:0051954 8 8 0,000 5,802E-03 0,01843677 ! developmental induction GO:0031128 8 8 0,000 5,802E-03 0,01840504 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 5,802E-03 0,01837342 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 5,802E-03 0,0183419 ! actin filament polymerization GO:0030041 9 8 0,000 5,802E-03 0,01831049 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 5,802E-03 0,01827919 ! peptide hormone processing GO:0016486 8 8 0,000 5,802E-03 0,018248 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 5,802E-03 0,01821691 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 5,802E-03 0,01818593 ! lactation GO:0007595 10 9 0,000 6,526E-03 0,0204185 ! embryonic pattern specification GO:0009880 10 9 0,000 6,526E-03 0,02038389 ! positive regulation of cell size GO:0045793 9 9 0,000 6,526E-03 0,0203494 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 6,526E-03 0,02031503 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 6,526E-03 0,02028077 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 6,526E-03 0,02024663 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 6,526E-03 0,0202126 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 6,526E-03 0,02017869 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 6,526E-03 0,02014489 ! viral genome replication GO:0019079 9 9 0,000 6,526E-03 0,0201112 ! phospholipid catabolic process GO:0009395 9 9 0,000 6,526E-03 0,02007762 ! copper ion transport GO:0006825 9 9 0,000 6,526E-03 0,02004416 ! lipid phosphorylation GO:0046834 9 9 0,000 6,526E-03 0,02001081 ! aminoglycan catabolic process GO:0006026 9 9 0,000 6,526E-03 0,01997757 ! Golgi vesicle budding GO:0048194 9 9 0,000 6,526E-03 0,01994444 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 6,526E-03 0,01991142 ! RNA polyadenylation GO:0043631 9 9 0,000 6,526E-03 0,01987851 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 6,526E-03 0,0198457 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 6,526E-03 0,01981301 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 6,526E-03 0,01978042 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 6,526E-03 0,01974794 ! phospholipid efflux GO:0033700 9 9 0,000 6,526E-03 0,01971557 ! response to alkaloid GO:0043279 10 9 0,000 6,526E-03 0,0196833 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 6,526E-03 0,01965114 ! cytokine biosynthetic process GO:0042089 9 9 0,000 6,526E-03 0,01961908 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 6,526E-03 0,01958713 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 6,526E-03 0,01955528 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 6,526E-03 0,01952353 ! response to ethanol GO:0045471 9 9 0,000 6,526E-03 0,01949189 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 6,526E-03 0,01946035 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 6,526E-03 0,01942891 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 6,526E-03 0,01939758 ! methionine metabolic process GO:0006555 9 9 0,000 6,526E-03 0,01936634 ! glutamine metabolic process GO:0006541 9 9 0,000 6,526E-03 0,0193352 ! cerebral cortex development GO:0021987 9 9 0,000 6,526E-03 0,01930417 ! response to osmotic stress GO:0006970 9 9 0,000 6,526E-03 0,01927323 ! pigmentation during development GO:0048066 9 9 0,000 6,526E-03 0,01924239 ! reverse cholesterol transport GO:0043691 9 9 0,000 6,526E-03 0,01921166 ! central nervous system neuron development GO:0021954 10 9 0,000 6,526E-03 0,01918102 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 6,526E-03 0,01915047 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 6,526E-03 0,01912003 ! substrate-bound cell migration GO:0006929 9 9 0,000 6,526E-03 0,01908968 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 6,526E-03 0,01905942 ! negative regulation of caspase activity GO:0043154 9 9 0,000 6,526E-03 0,01902927 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 6,526E-03 0,0189992 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 6,526E-03 0,01896924 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 6,526E-03 0,01893936 ! regulation of dephosphorylation GO:0035303 9 9 0,000 6,526E-03 0,01890959 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 6,526E-03 0,0188799 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 6,526E-03 0,01885031 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 6,526E-03 0,01882081 ! behavioral interaction between organisms GO:0051705 9 9 0,000 6,526E-03 0,0187914 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 6,526E-03 0,01876209 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 6,526E-03 0,01873286 ! DNA replication initiation GO:0006270 9 9 0,000 6,526E-03 0,01870373 ! prostaglandin metabolic process GO:0006693 9 9 0,000 6,526E-03 0,01867468 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 6,526E-03 0,01864573 ! regulation of cellular pH GO:0030641 9 9 0,000 6,526E-03 0,01861687 ! histone acetylation GO:0016573 9 9 0,000 6,526E-03 0,01858809 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 6,526E-03 0,01855941 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 6,526E-03 0,01853081 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 6,526E-03 0,0185023 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 6,526E-03 0,01847388 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 6,526E-03 0,01844555 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 6,526E-03 0,0184173 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 6,526E-03 0,01838914 ! negative regulation of protein secretion GO:0050709 9 9 0,000 6,526E-03 0,01836106 ! regulation of leukocyte migration GO:0002685 9 9 0,000 6,526E-03 0,01833307 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 6,526E-03 0,01830517 ! collagen catabolic process GO:0030574 9 9 0,000 6,526E-03 0,01827735 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 6,526E-03 0,01824962 ! purine base metabolic process GO:0006144 9 9 0,000 6,526E-03 0,01822196 ! gas transport GO:0015669 9 9 0,000 6,526E-03 0,0181944 ! cholesterol efflux GO:0033344 9 9 0,000 6,526E-03 0,01816691 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 6,526E-03 0,01813951 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 6,526E-03 0,01811219 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 6,526E-03 0,01808496 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 6,526E-03 0,0180578 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 6,526E-03 0,01803073 ! defense response to virus GO:0051607 9 9 0,000 6,526E-03 0,01800374 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 6,526E-03 0,01797683 ! actin filament-based movement GO:0030048 9 9 0,000 6,526E-03 0,01794999 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 6,526E-03 0,01792324 ! protein import into nucleus, docking GO:0000059 10 10 0,000 7,248E-03 0,0198793 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 7,248E-03 0,01984976 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 7,248E-03 0,01982031 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 7,248E-03 0,01979095 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 7,248E-03 0,01976167 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 7,248E-03 0,01973248 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 7,248E-03 0,01970338 ! neuron maturation GO:0042551 10 10 0,000 7,248E-03 0,01967436 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 7,248E-03 0,01964542 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 7,248E-03 0,01961658 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 7,248E-03 0,01958781 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 7,248E-03 0,01955913 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 7,248E-03 0,01953054 ! hormone secretion GO:0046879 10 10 0,000 7,248E-03 0,01950203 ! glucosamine metabolic process GO:0006041 10 10 0,000 7,248E-03 0,0194736 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 7,248E-03 0,01944525 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 7,248E-03 0,01941699 ! inositol metabolic process GO:0006020 10 10 0,000 7,248E-03 0,01938881 ! cAMP metabolic process GO:0046058 10 10 0,000 7,248E-03 0,01936071 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 7,248E-03 0,01933269 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 7,248E-03 0,01930475 ! forelimb morphogenesis GO:0035136 10 10 0,000 7,248E-03 0,0192769 ! glial cell development GO:0021782 10 10 0,000 7,248E-03 0,01924912 ! phototransduction GO:0007602 11 10 0,000 7,248E-03 0,01922142 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 7,248E-03 0,01919381 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 7,248E-03 0,01916627 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 7,248E-03 0,01913881 ! fat cell differentiation GO:0045444 10 10 0,000 7,248E-03 0,01911143 ! myoblast differentiation GO:0045445 10 10 0,000 7,248E-03 0,01908413 ! centrosome cycle GO:0007098 10 10 0,000 7,248E-03 0,0190569 ! inactivation of MAPK activity GO:0000188 10 10 0,000 7,248E-03 0,01902976 ! positive regulation of proteolysis GO:0045862 10 10 0,000 7,248E-03 0,01900269 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 7,248E-03 0,01897569 ! regulation of survival gene product expression GO:0045884 10 10 0,000 7,248E-03 0,01894878 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 7,248E-03 0,01892194 ! epidermis morphogenesis GO:0048730 10 10 0,000 7,248E-03 0,01889518 ! protein polyubiquitination GO:0000209 10 10 0,000 7,248E-03 0,01886849 ! glutamate metabolic process GO:0006536 11 10 0,000 7,248E-03 0,01884187 ! plasma membrane organization GO:0007009 10 10 0,000 7,248E-03 0,01881534 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 7,248E-03 0,01878887 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 7,248E-03 0,01876248 ! lysosomal transport GO:0007041 10 10 0,000 7,248E-03 0,01873617 ! cellular response to unfolded protein GO:0034620 10 10 0,000 7,248E-03 0,01870993 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 7,248E-03 0,01868376 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 7,248E-03 0,01865767 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 7,248E-03 0,01863164 ! exocrine system development GO:0035272 10 10 0,000 7,248E-03 0,01860569 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 7,248E-03 0,01857982 ! neuromuscular junction development GO:0007528 10 10 0,000 7,248E-03 0,01855401 ! embryo implantation GO:0007566 11 10 0,000 7,248E-03 0,01852828 ! regulation of protein binding GO:0043393 11 10 0,000 7,248E-03 0,01850262 ! protein targeting to peroxisome GO:0006625 10 10 0,000 7,248E-03 0,01847702 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 7,248E-03 0,0184515 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 7,248E-03 0,01842605 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 7,248E-03 0,01840067 ! protein export from nucleus GO:0006611 10 10 0,000 7,248E-03 0,01837536 ! negative regulation of immune response GO:0050777 10 10 0,000 7,248E-03 0,01835012 ! cytolysis GO:0019835 10 10 0,000 7,248E-03 0,01832495 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 7,248E-03 0,01829985 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 7,248E-03 0,01827481 ! regulation of B cell differentiation GO:0045577 10 10 0,000 7,248E-03 0,01824985 ! histone deacetylation GO:0016575 10 10 0,000 7,248E-03 0,01822495 ! mRNA splice site selection GO:0006376 11 10 0,000 7,248E-03 0,01820012 ! synaptic vesicle transport GO:0048489 11 10 0,000 7,248E-03 0,01817536 ! gland morphogenesis GO:0022612 10 10 0,000 7,248E-03 0,01815066 ! positive regulation of neurological system process GO:0031646 10 10 0,000 7,248E-03 0,01812604 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 7,248E-03 0,01810148 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 7,248E-03 0,01807698 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 7,248E-03 0,01805255 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 7,248E-03 0,01802819 ! regulation of epidermis development GO:0045682 10 10 0,000 7,248E-03 0,01800389 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 7,248E-03 0,01797966 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 7,248E-03 0,0179555 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 7,248E-03 0,01793139 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 7,248E-03 0,01790736 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 7,248E-03 0,01788339 ! nerve development GO:0021675 10 10 0,000 7,248E-03 0,01785948 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 7,248E-03 0,01783563 ! gut development GO:0048565 10 10 0,000 7,248E-03 0,01781185 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 7,248E-03 0,01778813 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 7,248E-03 0,01776448 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 7,248E-03 0,01774089 ! mRNA 3'-end processing GO:0031124 10 10 0,000 7,248E-03 0,01771736 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 7,248E-03 0,01769389 ! negative regulation of coagulation GO:0050819 11 10 0,000 7,248E-03 0,01767049 ! protein stabilization GO:0050821 10 10 0,000 7,248E-03 0,01764715 ! protein secretion GO:0009306 11 11 0,000 7,971E-03 0,01938061 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 7,971E-03 0,01935508 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 7,971E-03 0,01932961 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 7,971E-03 0,01930421 ! negative regulation of defense response GO:0031348 11 11 0,000 7,971E-03 0,01927888 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 7,971E-03 0,01925361 ! determination of bilateral symmetry GO:0009855 11 11 0,000 7,971E-03 0,01922841 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 7,971E-03 0,01920327 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 7,971E-03 0,01917821 ! skin development GO:0043588 11 11 0,000 7,971E-03 0,0191532 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 7,971E-03 0,01912826 ! signal complex assembly GO:0007172 11 11 0,000 7,971E-03 0,01910339 ! microtubule-based transport GO:0010970 11 11 0,000 7,971E-03 0,01907858 ! endothelial cell migration GO:0043542 11 11 0,000 7,971E-03 0,01905383 ! peroxisomal transport GO:0043574 11 11 0,000 7,971E-03 0,01902915 ! protein amino acid methylation GO:0006479 11 11 0,000 7,971E-03 0,01900453 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 7,971E-03 0,01897998 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 7,971E-03 0,01895549 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 7,971E-03 0,01893106 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 7,971E-03 0,0189067 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 7,971E-03 0,0188824 ! T cell proliferation GO:0042098 11 11 0,000 7,971E-03 0,01885816 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 7,971E-03 0,01883398 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 7,971E-03 0,01880987 ! regulation of viral genome replication GO:0045069 11 11 0,000 7,971E-03 0,01878581 ! spinal cord development GO:0021510 11 11 0,000 7,971E-03 0,01876182 ! activation of MAPKK activity GO:0000186 12 11 0,000 7,971E-03 0,01873789 ! smooth muscle contraction GO:0006939 11 11 0,000 7,971E-03 0,01871402 ! cellular response to starvation GO:0009267 11 11 0,000 7,971E-03 0,01869021 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 7,971E-03 0,01866646 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 7,971E-03 0,01864277 ! digestive system process GO:0022600 11 11 0,000 7,971E-03 0,01861914 ! mitotic spindle organization GO:0007052 11 11 0,000 7,971E-03 0,01859558 ! fucose metabolic process GO:0006004 11 11 0,000 7,971E-03 0,01857207 ! membrane budding GO:0006900 11 11 0,000 7,971E-03 0,01854862 ! apoptotic nuclear changes GO:0030262 11 11 0,000 7,971E-03 0,01852523 ! monoamine transport GO:0015844 11 11 0,000 7,971E-03 0,0185019 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 7,971E-03 0,01847862 ! response to lipopolysaccharide GO:0032496 11 11 0,000 7,971E-03 0,01845541 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 7,971E-03 0,01843225 ! body fluid secretion GO:0007589 11 11 0,000 7,971E-03 0,01840915 ! G1/S transition checkpoint GO:0031575 12 11 0,000 7,971E-03 0,01838611 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 7,971E-03 0,01836313 ! intermediate filament-based process GO:0045103 11 11 0,000 7,971E-03 0,01834021 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 7,971E-03 0,01831734 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 7,971E-03 0,01829453 ! membrane depolarization GO:0051899 11 11 0,000 7,971E-03 0,01827177 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 7,971E-03 0,01824907 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 7,971E-03 0,01822643 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 7,971E-03 0,01820385 ! oogenesis GO:0048477 11 11 0,000 7,971E-03 0,01818132 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 7,971E-03 0,01815884 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 7,971E-03 0,01813643 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 7,971E-03 0,01811406 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 7,971E-03 0,01809176 ! muscle maintenance GO:0046716 12 11 0,000 7,971E-03 0,0180695 ! vitamin A metabolic process GO:0006776 11 11 0,000 7,971E-03 0,0180473 ! hindbrain development GO:0030902 11 11 0,000 7,971E-03 0,01802516 ! steroid catabolic process GO:0006706 11 11 0,000 7,971E-03 0,01800307 ! endocrine process GO:0050886 11 11 0,000 7,971E-03 0,01798103 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 7,971E-03 0,01795905 ! proximal/distal pattern formation GO:0009954 11 11 0,000 7,971E-03 0,01793712 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 7,971E-03 0,01791525 ! RNA 3'-end processing GO:0031123 11 11 0,000 7,971E-03 0,01789343 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 7,971E-03 0,01787166 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 8,693E-03 0,01946701 ! translational initiation GO:0006413 12 12 0,000 8,693E-03 0,01944338 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 8,693E-03 0,01941981 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 8,693E-03 0,0193963 ! initiation of viral infection GO:0019059 12 12 0,000 8,693E-03 0,01937285 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 8,693E-03 0,01934945 ! iron ion transport GO:0006826 13 12 0,000 8,693E-03 0,01932611 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 8,693E-03 0,01930283 ! amino sugar metabolic process GO:0006040 12 12 0,000 8,693E-03 0,0192796 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 8,693E-03 0,01925643 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 8,693E-03 0,01923331 ! heterophilic cell adhesion GO:0007157 12 12 0,000 8,693E-03 0,01921025 ! collagen metabolic process GO:0032963 12 12 0,000 8,693E-03 0,01918724 ! hindlimb morphogenesis GO:0035137 12 12 0,000 8,693E-03 0,01916429 ! xenobiotic metabolic process GO:0006805 12 12 0,000 8,693E-03 0,01914139 ! glutamate signaling pathway GO:0007215 12 12 0,000 8,693E-03 0,01911855 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 8,693E-03 0,01909576 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 8,693E-03 0,01907303 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 8,693E-03 0,01905035 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 8,693E-03 0,01902773 ! actomyosin structure organization GO:0031032 12 12 0,000 8,693E-03 0,01900516 ! microtubule organizing center organization GO:0031023 12 12 0,000 8,693E-03 0,01898264 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 8,693E-03 0,01896017 ! retinoid metabolic process GO:0001523 12 12 0,000 8,693E-03 0,01893776 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 8,693E-03 0,0189154 ! positive regulation of innate immune response GO:0045089 12 12 0,000 8,693E-03 0,0188931 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 8,693E-03 0,01887084 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 8,693E-03 0,01884864 ! acute-phase response GO:0006953 12 12 0,000 8,693E-03 0,01882649 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 8,693E-03 0,0188044 ! vacuolar transport GO:0007034 12 12 0,000 8,693E-03 0,01878235 ! polysaccharide catabolic process GO:0000272 12 12 0,000 8,693E-03 0,01876036 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 8,693E-03 0,01873842 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 8,693E-03 0,01871653 ! barbed-end actin filament capping GO:0051016 12 12 0,000 8,693E-03 0,01869469 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 8,693E-03 0,0186729 ! male gonad development GO:0008584 12 12 0,000 8,693E-03 0,01865116 ! regulation of insulin secretion GO:0050796 12 12 0,000 8,693E-03 0,01862947 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 8,693E-03 0,01860784 ! renal system process GO:0003014 12 12 0,000 8,693E-03 0,01858625 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 8,693E-03 0,01856471 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 8,693E-03 0,01854323 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 8,693E-03 0,01852179 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 8,693E-03 0,0185004 ! pallium development GO:0021543 13 12 0,000 8,693E-03 0,01847906 ! cell fate determination GO:0001709 12 12 0,000 8,693E-03 0,01845777 ! regulation of chromosome organization GO:0033044 12 12 0,000 8,693E-03 0,01843653 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 8,693E-03 0,01841534 ! somitogenesis GO:0001756 13 12 0,000 8,693E-03 0,0183942 ! G1 phase GO:0051318 13 12 0,000 8,693E-03 0,0183731 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 8,693E-03 0,01835206 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 8,693E-03 0,01833106 ! detection of light stimulus GO:0009583 13 12 0,000 8,693E-03 0,01831011 ! synaptogenesis GO:0007416 12 12 0,000 8,693E-03 0,01828921 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 8,693E-03 0,01826835 ! hormone transport GO:0009914 12 12 0,000 8,693E-03 0,01824755 ! neurotransmitter secretion GO:0007269 14 12 0,000 8,693E-03 0,01822679 ! heme biosynthetic process GO:0006783 12 12 0,000 8,693E-03 0,01820608 ! spermatid differentiation GO:0048515 13 12 0,000 8,693E-03 0,01818541 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 8,693E-03 0,01816479 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 8,693E-03 0,01814422 ! neural tube closure GO:0001843 13 12 0,000 8,693E-03 0,0181237 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 8,693E-03 0,01810322 ! negative regulation of translation GO:0017148 12 12 0,000 8,693E-03 0,01808278 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 8,693E-03 0,0180624 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 8,693E-03 0,01804206 ! positive regulation of DNA replication GO:0045740 14 13 0,000 9,415E-03 0,0195179 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 9,415E-03 0,01949597 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 9,415E-03 0,01947409 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 9,415E-03 0,01945226 ! phenol metabolic process GO:0018958 13 13 0,000 9,415E-03 0,01943047 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 9,415E-03 0,01940874 ! gluconeogenesis GO:0006094 13 13 0,000 9,415E-03 0,01938705 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 9,415E-03 0,01936542 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 9,415E-03 0,01934383 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 9,415E-03 0,01932229 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 9,415E-03 0,01930079 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 9,415E-03 0,01927935 ! regeneration GO:0031099 13 13 0,000 9,415E-03 0,01925795 ! keratinization GO:0031424 13 13 0,000 9,415E-03 0,0192366 ! post-embryonic development GO:0009791 14 13 0,000 9,415E-03 0,0192153 ! negative regulation of protein modification process GO:0031400 13 13 0,000 9,415E-03 0,01919404 ! patterning of blood vessels GO:0001569 13 13 0,000 9,415E-03 0,01917283 ! vasculogenesis GO:0001570 13 13 0,000 9,415E-03 0,01915167 ! regulation of DNA recombination GO:0000018 13 13 0,000 9,415E-03 0,01913055 ! regulation of innate immune response GO:0045088 13 13 0,000 9,415E-03 0,01910949 ! mitochondrial membrane organization GO:0007006 13 13 0,000 9,415E-03 0,01908846 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 9,415E-03 0,01906749 ! negative regulation of DNA replication GO:0008156 13 13 0,000 9,415E-03 0,01904656 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 9,415E-03 0,01902567 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 9,415E-03 0,01900483 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 9,415E-03 0,01898404 ! autophagy GO:0006914 13 13 0,000 9,415E-03 0,01896329 ! receptor metabolic process GO:0043112 14 13 0,000 9,415E-03 0,01894259 ! actin filament bundle formation GO:0051017 13 13 0,000 9,415E-03 0,01892193 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 9,415E-03 0,01890132 ! ureteric bud development GO:0001657 13 13 0,000 9,415E-03 0,01888075 ! cell aging GO:0007569 13 13 0,000 9,415E-03 0,01886023 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 9,415E-03 0,01883975 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 9,415E-03 0,01881932 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 9,415E-03 0,01879893 ! coenzyme catabolic process GO:0009109 13 13 0,000 9,415E-03 0,01877858 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 9,415E-03 0,01875828 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 9,415E-03 0,01873803 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 9,415E-03 0,01871781 ! regulation of viral reproduction GO:0050792 13 13 0,000 9,415E-03 0,01869764 ! nucleobase metabolic process GO:0009112 13 13 0,000 9,415E-03 0,01867752 ! regulation of axonogenesis GO:0050770 14 13 0,000 9,415E-03 0,01865743 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 9,415E-03 0,01863739 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 9,415E-03 0,0186174 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 9,415E-03 0,01859744 ! vasodilation GO:0042311 14 13 0,000 9,415E-03 0,01857753 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 9,415E-03 0,01855766 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 9,415E-03 0,01853783 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 9,415E-03 0,01851805 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 9,415E-03 0,01849831 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 9,415E-03 0,01847861 ! neutrophil chemotaxis GO:0030593 14 13 0,000 9,415E-03 0,01845895 ! long-chain fatty acid transport GO:0015909 13 13 0,000 9,415E-03 0,01843933 ! immunoglobulin production GO:0002377 13 13 0,000 9,415E-03 0,01841976 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 9,415E-03 0,01840023 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 9,415E-03 0,01838073 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 9,415E-03 0,01836128 ! cell-cell junction organization GO:0045216 13 13 0,000 9,415E-03 0,01834187 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 9,415E-03 0,01832251 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 9,415E-03 0,01830318 ! response to cytokine stimulus GO:0034097 13 13 0,000 9,415E-03 0,01828389 ! activation of JUN kinase activity GO:0007257 13 13 0,000 9,415E-03 0,01826464 ! terpenoid metabolic process GO:0006721 13 13 0,000 9,415E-03 0,01824544 ! alkene biosynthetic process GO:0043450 13 13 0,000 9,415E-03 0,01822627 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 9,415E-03 0,01820715 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 9,415E-03 0,01818806 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 9,415E-03 0,01816902 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 9,415E-03 0,01815001 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 9,415E-03 0,01813105 ! blastocyst development GO:0001824 13 13 0,000 9,415E-03 0,01811212 ! telomere organization GO:0032200 13 13 0,000 9,415E-03 0,01809324 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 9,415E-03 0,01807439 ! regulation of amine transport GO:0051952 13 13 0,000 9,415E-03 0,01805558 ! tissue homeostasis GO:0001894 13 13 0,000 9,415E-03 0,01803681 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 9,415E-03 0,01801808 ! protein tetramerization GO:0051262 13 13 0,000 9,415E-03 0,01799939 ! neuron fate commitment GO:0048663 14 14 0,000 0,01013603 0,01935824 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,01013603 0,0193382 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,01013603 0,0193182 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,01013603 0,01929825 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,01013603 0,01927833 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,01013603 0,01925846 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,01013603 0,01923862 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,01013603 0,01921883 ! protein amino acid acylation GO:0043543 14 14 0,000 0,01013603 0,01919908 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,01013603 0,01917937 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,01013603 0,0191597 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,01013603 0,01914007 ! vesicle docking GO:0048278 14 14 0,000 0,01013603 0,01912047 ! superoxide metabolic process GO:0006801 15 14 0,000 0,01013603 0,01910092 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,01013603 0,01908141 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,01013603 0,01906194 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,01013603 0,01904251 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,01013603 0,01902312 ! hair cycle GO:0042633 14 14 0,000 0,01013603 0,01900377 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,01013603 0,01898445 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,01013603 0,01896518 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,01013603 0,01894595 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,01013603 0,01892675 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,01013603 0,01890759 ! lysosome organization GO:0007040 14 14 0,000 0,01013603 0,01888848 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,01013603 0,0188694 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,01013603 0,01885036 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,01013603 0,01883135 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,01013603 0,01881239 ! primary neural tube formation GO:0014020 15 14 0,000 0,01013603 0,01879346 ! peptide cross-linking GO:0018149 14 14 0,000 0,01013603 0,01877458 ! regulation of behavior GO:0050795 14 14 0,000 0,01013603 0,01875573 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,01013603 0,01873691 ! base-excision repair GO:0006284 14 14 0,000 0,01013603 0,01871814 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,01013603 0,0186994 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,01013603 0,0186807 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,01013603 0,01866204 ! formation of primary germ layer GO:0001704 14 14 0,000 0,01013603 0,01864342 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,01013603 0,01862483 ! collagen fibril organization GO:0030199 14 14 0,000 0,01013603 0,01860628 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,01013603 0,01858776 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,01013603 0,01856929 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,01013603 0,01855085 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,01013603 0,01853244 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,01013603 0,01851408 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,01013603 0,01849575 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,01013603 0,01847745 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,01013603 0,01845919 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,01013603 0,01844097 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,01085687 0,01973296 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,01085687 0,01971352 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,01085687 0,01969411 ! positive regulation of ossification GO:0045778 15 15 0,000 0,01085687 0,01967475 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,01085687 0,01965542 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,01085687 0,01963613 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,01085687 0,01961688 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,01085687 0,01959767 ! response to vitamin GO:0033273 15 15 0,000 0,01085687 0,01957849 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,01085687 0,01955936 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,01085687 0,01954025 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,01085687 0,01952119 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,01085687 0,01950216 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,01085687 0,01948317 ! ovarian follicle development GO:0001541 15 15 0,000 0,01085687 0,01946422 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,01085687 0,01944531 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,01085687 0,01942643 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,01085687 0,01940759 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,01085687 0,01938878 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,01085687 0,01937001 ! heme metabolic process GO:0042168 15 15 0,000 0,01085687 0,01935128 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,01085687 0,01933258 ! chromosome condensation GO:0030261 15 15 0,000 0,01085687 0,01931392 ! response to starvation GO:0042594 15 15 0,000 0,01085687 0,01929529 ! response to ionizing radiation GO:0010212 16 15 0,000 0,01085687 0,01927671 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,01085687 0,01925815 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,01085687 0,01923964 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,01085687 0,01922115 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,01085687 0,01920271 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,01085687 0,0191843 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,01085687 0,01916592 ! phospholipid transport GO:0015914 15 15 0,000 0,01085687 0,01914758 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,01085687 0,01912927 ! glutathione metabolic process GO:0006749 16 15 0,000 0,01085687 0,019111 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,01085687 0,01909277 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,01085687 0,01907457 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,01085687 0,0190564 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,01085687 0,01903827 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,01085687 0,01902017 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,01085687 0,01900211 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,01085687 0,01898408 ! protein homooligomerization GO:0051260 15 15 0,000 0,01085687 0,01896609 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,01085687 0,01894813 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,0115773 0,02018634 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,0115773 0,02016726 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,0115773 0,02014822 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,0115773 0,02012921 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,0115773 0,02011024 ! learning GO:0007612 16 16 0,000 0,0115773 0,0200913 ! circadian rhythm GO:0007623 16 16 0,000 0,0115773 0,0200724 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,0115773 0,02005354 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,0115773 0,02003471 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,0115773 0,02001591 ! vacuole organization GO:0007033 16 16 0,000 0,0115773 0,01999715 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,0115773 0,01997843 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,0115773 0,01995974 ! vesicle targeting GO:0006903 17 16 0,000 0,0115773 0,01994109 ! segmentation GO:0035282 17 16 0,000 0,0115773 0,01992247 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,0115773 0,01990388 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,0115773 0,01988533 ! iron ion homeostasis GO:0055072 16 16 0,000 0,0115773 0,01986682 ! positive regulation of cell development GO:0010720 16 16 0,000 0,0115773 0,01984834 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,0115773 0,01982989 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,0115773 0,01981148 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,0115773 0,0197931 ! cell fate specification GO:0001708 16 16 0,000 0,0115773 0,01977476 ! pentose metabolic process GO:0019321 16 16 0,000 0,0115773 0,01975645 ! fatty acid transport GO:0015908 16 16 0,000 0,0115773 0,01973817 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,0115773 0,01971993 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,0115773 0,01970172 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,0115773 0,01968355 ! cofactor catabolic process GO:0051187 16 16 0,000 0,0115773 0,0196654 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,0115773 0,0196473 ! polyol metabolic process GO:0019751 16 16 0,000 0,0115773 0,01962922 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,0115773 0,01961118 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,0115773 0,01959317 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,0115773 0,0195752 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,0115773 0,01955725 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,0115773 0,01953934 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,0115773 0,01952147 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,0115773 0,01950362 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,0115773 0,01948581 ! regulation of coagulation GO:0050818 17 16 0,000 0,0115773 0,01946803 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,0122973 0,02065992 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,0122973 0,0206411 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,0122973 0,02062232 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,0122973 0,02060357 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,0122973 0,02058486 ! myelination GO:0042552 17 17 0,000 0,0122973 0,02056618 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,0122973 0,02054754 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,0122973 0,02052892 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,0122973 0,02051035 ! leukocyte adhesion GO:0007159 17 17 0,000 0,0122973 0,0204918 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,0122973 0,02047329 ! sensory perception of smell GO:0007608 17 17 0,000 0,0122973 0,02045481 ! glucose transport GO:0015758 17 17 0,000 0,0122973 0,02043637 ! cell junction assembly GO:0034329 18 17 0,000 0,0122973 0,02041796 ! tissue remodeling GO:0048771 17 17 0,000 0,0122973 0,02039958 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,0122973 0,02038123 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,0122973 0,02036292 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,0122973 0,02034464 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,0122973 0,0203264 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,0122973 0,02030818 ! neural crest cell development GO:0014032 19 17 0,000 0,0122973 0,02029 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,0122973 0,02027185 ! negative regulation of cell development GO:0010721 18 17 0,000 0,0122973 0,02025374 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,0122973 0,02023565 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,0122973 0,0202176 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,0122973 0,02019958 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,0122973 0,0201816 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,0122973 0,02016364 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,0122973 0,02014572 ! pigmentation GO:0043473 17 17 0,000 0,0122973 0,02012783 ! adult locomotory behavior GO:0008344 17 17 0,000 0,0122973 0,02010997 ! embryonic organ development GO:0048568 17 17 0,000 0,0122973 0,02009214 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,0122973 0,02007434 ! liver development GO:0001889 17 17 0,000 0,0122973 0,02005658 ! gene silencing GO:0016458 17 17 0,000 0,0122973 0,02003884 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,01301689 0,02119269 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,01301689 0,02117399 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,01301689 0,02115532 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,01301689 0,02113668 ! meiosis I GO:0007127 18 18 0,000 0,01301689 0,02111807 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,01301689 0,0210995 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,01301689 0,02108096 ! membrane docking GO:0022406 18 18 0,000 0,01301689 0,02106245 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,01301689 0,02104397 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,01301689 0,02102553 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,01301689 0,02100712 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,01301689 0,02098874 ! hexose transport GO:0008645 18 18 0,000 0,01301689 0,02097039 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,01301689 0,02095208 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,01301689 0,02093379 ! striated muscle contraction GO:0006941 18 18 0,000 0,01301689 0,02091554 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,01301689 0,02089732 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,01301689 0,02087914 ! ceramide metabolic process GO:0006672 18 18 0,000 0,01301689 0,02086098 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,01301689 0,02084286 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,01301689 0,02082476 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,01301689 0,0208067 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,01301689 0,02078867 ! B cell differentiation GO:0030183 18 18 0,000 0,01301689 0,02077067 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,01301689 0,02075271 ! ensheathment of neurons GO:0007272 18 18 0,000 0,01301689 0,02073477 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,01301689 0,02071686 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,01301689 0,02069899 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,01301689 0,02068114 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,01301689 0,02066333 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,01301689 0,02064555 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,01373606 0,02176746 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,01373606 0,02174875 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,01373606 0,02173009 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,01373606 0,02171145 ! glial cell differentiation GO:0010001 19 19 0,000 0,01373606 0,02169285 ! regulation of pH GO:0006885 19 19 0,000 0,01373606 0,02167427 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,01373606 0,02165573 ! feeding behavior GO:0007631 19 19 0,000 0,01373606 0,02163722 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,01373606 0,02161874 ! peroxisome organization GO:0007031 19 19 0,000 0,01373606 0,0216003 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,01373606 0,02158188 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,01373606 0,0215635 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,01373606 0,02154515 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,01373606 0,02152683 ! metanephros development GO:0001656 19 19 0,000 0,01373606 0,02150854 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,01373606 0,02149028 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,01373606 0,02147205 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,01373606 0,02145386 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,01373606 0,02143569 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,01373606 0,02141756 ! peripheral nervous system development GO:0007422 19 19 0,000 0,01373606 0,02139945 ! regulation of protein stability GO:0031647 19 19 0,000 0,01373606 0,02138138 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,01373606 0,02136333 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,01373606 0,02134532 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,01373606 0,02132734 ! eye morphogenesis GO:0048592 19 19 0,000 0,01373606 0,02130939 ! regulation of cell shape GO:0008360 21 19 0,000 0,01373606 0,02129146 ! placenta development GO:0001890 19 19 0,000 0,01373606 0,02127357 ! response to heat GO:0009408 19 19 0,000 0,01373606 0,02125571 ! vesicle localization GO:0051648 20 19 0,000 0,01373606 0,02123788 ! regulation of muscle development GO:0048634 21 20 0,000 0,0144548 0,02233043 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,0144548 0,02231173 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,0144548 0,02229305 ! negative regulation of binding GO:0051100 21 20 0,000 0,0144548 0,02227441 ! organic ether metabolic process GO:0018904 20 20 0,000 0,0144548 0,02225581 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,0144548 0,02223723 ! neural tube development GO:0021915 21 20 0,000 0,0144548 0,02221868 ! nucleus organization GO:0006997 20 20 0,000 0,0144548 0,02220017 ! phagocytosis GO:0006909 21 20 0,000 0,0144548 0,02218168 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,0144548 0,02216323 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,0144548 0,0221448 ! protein targeting to membrane GO:0006612 22 20 0,000 0,0144548 0,02212641 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,0144548 0,02210805 ! chromatin remodeling GO:0006338 20 20 0,000 0,0144548 0,02208972 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,0144548 0,02207142 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,0144548 0,02205315 ! lipid oxidation GO:0034440 20 20 0,000 0,0144548 0,02203491 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,0144548 0,02201669 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,0144548 0,02199851 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,0144548 0,02198036 ! RNA modification GO:0009451 20 20 0,000 0,0144548 0,02196224 ! single fertilization GO:0007338 21 20 0,000 0,0144548 0,02194415 ! regulation of B cell activation GO:0050864 20 20 0,000 0,0144548 0,02192609 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,01517313 0,02299677 ! mRNA catabolic process GO:0006402 21 21 0,000 0,01517313 0,02297788 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,01517313 0,02295901 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,01517313 0,02294018 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,01517313 0,02292138 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,01517313 0,0229026 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,01517313 0,02288386 ! Notch signaling pathway GO:0007219 22 21 0,000 0,01517313 0,02286515 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,01517313 0,02284647 ! ear morphogenesis GO:0042471 21 21 0,000 0,01517313 0,02282782 ! organic anion transport GO:0015711 21 21 0,000 0,01517313 0,0228092 ! cholesterol transport GO:0030301 21 21 0,000 0,01517313 0,02279061 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,01517313 0,02277205 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,01517313 0,02275352 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,01517313 0,02273502 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,01517313 0,02271655 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,01517313 0,02269811 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,01517313 0,02267971 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,01517313 0,02266133 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,01517313 0,02264298 ! regulation of proteolysis GO:0030162 21 21 0,000 0,01517313 0,02262466 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,01517313 0,02260637 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,01517313 0,02258811 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,01517313 0,02256988 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,01517313 0,02255168 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,01589104 0,02359966 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,01589104 0,02358066 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,01589104 0,02356169 ! sister chromatid segregation GO:0000819 22 22 0,000 0,01589104 0,02354275 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,01589104 0,02352384 ! regulation of ion transport GO:0043269 22 22 0,000 0,01589104 0,02350496 ! odontogenesis GO:0042476 22 22 0,000 0,01589104 0,02348611 ! cell junction organization GO:0034330 23 22 0,000 0,01589104 0,02346729 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,01589104 0,02344851 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,01589104 0,02342975 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,01589104 0,02341102 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,01589104 0,02339232 ! ovulation cycle process GO:0022602 22 22 0,000 0,01589104 0,02337365 ! spindle organization GO:0007051 22 22 0,000 0,01589104 0,02335501 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,01589104 0,0233364 ! cell chemotaxis GO:0060326 23 22 0,000 0,01589104 0,02331782 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,01589104 0,02329927 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,01589104 0,02328075 ! male sex differentiation GO:0046661 22 22 0,000 0,01589104 0,02326226 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,01589104 0,0232438 ! biopolymer methylation GO:0043414 22 22 0,000 0,01589104 0,02322536 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,01589104 0,02320696 ! detection of external stimulus GO:0009581 23 22 0,000 0,01589104 0,02318859 ! neuron migration GO:0001764 22 22 0,000 0,01589104 0,02317024 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,01589104 0,02315192 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,01589104 0,02313364 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,01589104 0,02311538 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,01589104 0,02309715 ! aerobic respiration GO:0009060 22 22 0,000 0,01589104 0,02307895 ! cytokine production GO:0001816 22 22 0,000 0,01589104 0,02306077 ! cytokinesis GO:0000910 23 22 0,000 0,01589104 0,02304263 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,01589104 0,02302451 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,01660853 0,02404518 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,01660853 0,02402631 ! viral infectious cycle GO:0019058 23 23 0,000 0,01660853 0,02400746 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,01660853 0,02398865 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,01660853 0,02396986 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,01660853 0,02395111 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,01660853 0,02393238 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,01660853 0,02391368 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,01660853 0,02389502 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,01660853 0,02387638 ! endocrine system development GO:0035270 23 23 0,000 0,01660853 0,02385777 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,01660853 0,02383919 ! positive regulation of growth GO:0045927 23 23 0,000 0,01660853 0,02382064 ! female gonad development GO:0008585 23 23 0,000 0,01660853 0,02380211 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,01660853 0,02378362 ! lipid homeostasis GO:0055088 23 23 0,000 0,01660853 0,02376515 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,01660853 0,02374672 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,01660853 0,02372831 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,01660853 0,02370993 ! cell projection assembly GO:0030031 25 23 0,000 0,01660853 0,02369158 ! mitochondrial transport GO:0006839 24 24 0,000 0,0173256 0,02469534 ! regulation of action potential GO:0001508 24 24 0,000 0,0173256 0,02467626 ! gliogenesis GO:0042063 24 24 0,000 0,0173256 0,0246572 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,0173256 0,02463818 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,0173256 0,02461918 ! glucose homeostasis GO:0042593 24 24 0,000 0,0173256 0,02460021 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,0173256 0,02458128 ! T cell differentiation GO:0030217 24 24 0,000 0,0173256 0,02456237 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,0173256 0,02454349 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,0173256 0,02452464 ! ovulation cycle GO:0042698 24 24 0,000 0,0173256 0,02450582 ! fertilization GO:0009566 25 24 0,000 0,0173256 0,02448702 ! maintenance of protein location GO:0045185 25 24 0,000 0,0173256 0,02446826 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,0173256 0,02444952 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,0173256 0,02443082 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,0173256 0,02441214 ! glucan metabolic process GO:0044042 25 24 0,000 0,0173256 0,02439349 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,01804225 0,02538311 ! negative regulation of secretion GO:0051048 26 25 0,000 0,01804225 0,02536375 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,01804225 0,02534441 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,01804225 0,02532511 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,01804225 0,02530584 ! cellular component disassembly GO:0022411 26 25 0,000 0,01804225 0,02528659 ! endosome transport GO:0016197 25 25 0,000 0,01804225 0,02526738 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,01804225 0,02524819 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,01804225 0,02522904 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,01804225 0,02520991 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,01804225 0,02519081 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,01804225 0,02517174 ! excretion GO:0007588 25 25 0,000 0,01804225 0,0251527 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,01804225 0,02513369 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,01804225 0,02511471 ! gastrulation GO:0007369 25 25 0,000 0,01804225 0,02509575 ! heart morphogenesis GO:0003007 25 25 0,000 0,01804225 0,02507683 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,01804225 0,02505793 ! regulation of endocytosis GO:0030100 25 25 0,000 0,01804225 0,02503906 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,01804225 0,02502022 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,01804225 0,02500141 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,01804225 0,02498262 ! positive regulation of binding GO:0051099 27 26 0,000 0,01875849 0,02595487 ! positive regulation of defense response GO:0031349 26 26 0,000 0,01875849 0,0259354 ! glycolysis GO:0006096 26 26 0,000 0,01875849 0,02591596 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,01875849 0,02589655 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,01875849 0,02587716 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,01875849 0,02585781 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,01875849 0,02583848 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,01875849 0,02581919 ! cellular defense response GO:0006968 26 26 0,000 0,01875849 0,02579992 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,01875849 0,02578068 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,01875849 0,02576147 ! double-strand break repair GO:0006302 27 26 0,000 0,01875849 0,02574229 ! regulation of protein secretion GO:0050708 26 26 0,000 0,01875849 0,02572313 ! germ cell development GO:0007281 27 26 0,000 0,01875849 0,02570401 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,01875849 0,02568491 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,01875849 0,02566584 ! response to insulin stimulus GO:0032868 28 26 0,000 0,01875849 0,0256468 ! maintenance of location in cell GO:0051651 27 26 0,000 0,01875849 0,02562779 ! synapse organization GO:0050808 26 26 0,000 0,01875849 0,02560881 ! chloride transport GO:0006821 27 27 0,000 0,0194743 0,02656635 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,0194743 0,0265467 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,0194743 0,02652708 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,0194743 0,02650749 ! learning or memory GO:0007611 28 27 0,000 0,0194743 0,02648793 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,0194743 0,02646839 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,0194743 0,02644889 ! peptide metabolic process GO:0006518 29 27 0,000 0,0194743 0,02642941 ! activation of caspase activity GO:0006919 27 27 0,000 0,0194743 0,02640996 ! mesenchymal cell development GO:0014031 29 27 0,000 0,0194743 0,02639054 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,0194743 0,02637115 ! defense response to bacterium GO:0042742 27 27 0,000 0,0194743 0,02635179 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,0194743 0,02633246 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,0194743 0,02631315 ! cell growth GO:0016049 27 27 0,000 0,0194743 0,02629388 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,0201897 0,02723984 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,0201897 0,02721991 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,0201897 0,02720002 ! carbohydrate transport GO:0008643 28 28 0,000 0,0201897 0,02718015 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,0201897 0,02716031 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,0201897 0,0271405 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,0201897 0,02712071 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,0201897 0,02710096 ! histone modification GO:0016570 28 28 0,000 0,0201897 0,02708124 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,0201897 0,02706154 ! developmental growth GO:0048589 28 28 0,000 0,0201897 0,02704188 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,0201897 0,02702224 ! cartilage development GO:0051216 29 28 0,000 0,0201897 0,02700263 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,02090468 0,0279386 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,02090468 0,02791836 ! viral reproductive process GO:0022415 29 29 0,000 0,02090468 0,02789814 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,02090468 0,02787795 ! leukocyte migration GO:0050900 30 29 0,000 0,02090468 0,0278578 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,02090468 0,02783767 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,02090468 0,02781757 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,02090468 0,0277975 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,02090468 0,02777746 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,02090468 0,02775744 ! tRNA processing GO:0008033 29 29 0,000 0,02090468 0,02773746 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,02090468 0,0277175 ! covalent chromatin modification GO:0016569 29 29 0,000 0,02090468 0,02769758 ! adult behavior GO:0030534 30 29 0,000 0,02090468 0,02767768 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,02090468 0,02765781 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,02090468 0,02763797 ! response to UV GO:0009411 29 29 0,000 0,02090468 0,02761816 ! transition metal ion transport GO:0000041 31 30 0,000 0,02161925 0,02854174 ! RNA catabolic process GO:0006401 30 30 0,000 0,02161925 0,02852131 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,02161925 0,02850091 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,02161925 0,02848054 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,02161925 0,02846019 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,02161925 0,02843988 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,02161925 0,0284196 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,02161925 0,02839934 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,02161925 0,02837911 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,02161925 0,02835891 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,02161925 0,02833874 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,02161925 0,0283186 ! response to temperature stimulus GO:0009266 30 30 0,000 0,02161925 0,02829849 ! regulation of ossification GO:0030278 30 30 0,000 0,02161925 0,0282784 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,02161925 0,02825835 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,02161925 0,02823832 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,02161925 0,02821832 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,02161925 0,02819835 ! vesicle organization GO:0016050 30 30 0,000 0,02161925 0,02817841 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,02161925 0,0281585 ! establishment of organelle localization GO:0051656 31 30 0,000 0,02161925 0,02813861 ! regulation of translational initiation GO:0006446 31 31 0,000 0,02233339 0,0290476 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,02233339 0,02902711 ! membrane fusion GO:0006944 31 31 0,000 0,02233339 0,02900666 ! B cell activation GO:0042113 31 31 0,000 0,02233339 0,02898623 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,02233339 0,02896583 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,02233339 0,02894546 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,02233339 0,02892512 ! ion transmembrane transport GO:0034220 31 31 0,000 0,02233339 0,02890481 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,02233339 0,02888452 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,02233339 0,02886427 ! digestion GO:0007586 31 31 0,000 0,02233339 0,02884404 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,02233339 0,02882384 ! regulation of DNA replication GO:0006275 32 31 0,000 0,02233339 0,02880367 ! regulation of heart contraction GO:0008016 31 31 0,000 0,02233339 0,02878353 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,02233339 0,02876341 ! camera-type eye development GO:0043010 31 31 0,000 0,02233339 0,02874333 ! extracellular matrix organization GO:0030198 31 31 0,000 0,02233339 0,02872327 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,02233339 0,02870324 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,02233339 0,02868324 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,02233339 0,02866326 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,02233339 0,02864332 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,02233339 0,0286234 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,02304712 0,02951761 ! cell redox homeostasis GO:0045454 32 32 0,000 0,02304712 0,02949712 ! muscle fiber development GO:0048747 32 32 0,000 0,02304712 0,02947665 ! glucose catabolic process GO:0006007 32 32 0,000 0,02304712 0,02945621 ! lipid modification GO:0030258 32 32 0,000 0,02304712 0,02943579 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,02304712 0,02941541 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,02304712 0,02939505 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,02304712 0,02937472 ! cell maturation GO:0048469 32 32 0,000 0,02304712 0,02935442 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,02304712 0,02933415 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,02304712 0,0293139 ! nuclear export GO:0051168 32 32 0,000 0,02304712 0,02929369 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,02304712 0,0292735 ! kidney development GO:0001822 32 32 0,000 0,02304712 0,02925334 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,02304712 0,02923321 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,02304712 0,0292131 ! maintenance of location GO:0051235 33 32 0,000 0,02304712 0,02919302 ! negative regulation of cell size GO:0045792 33 33 0,000 0,02376044 0,03007588 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,02376044 0,03005524 ! amino acid transport GO:0006865 33 33 0,000 0,02376044 0,03003462 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,02376044 0,03001404 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,02376044 0,02999348 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,02376044 0,02997295 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,02376044 0,02995245 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,02376044 0,02993198 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,02376044 0,02991153 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,02376044 0,02989111 ! regulation of actin filament length GO:0030832 34 34 0,000 0,02447333 0,03076695 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,02447333 0,03074598 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,02447333 0,03072503 ! ear development GO:0043583 34 34 0,000 0,02447333 0,03070412 ! muscle cell differentiation GO:0042692 35 34 0,000 0,02447333 0,03068323 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,02447333 0,03066237 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,02447333 0,03064154 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,02447333 0,03062074 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,02447333 0,03059997 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,02447333 0,03057922 ! secondary metabolic process GO:0019748 34 34 0,000 0,02447333 0,0305585 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,02447333 0,03053781 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,02447333 0,03051715 ! viral reproduction GO:0016032 34 34 0,000 0,02447333 0,03049652 ! detection of stimulus GO:0051606 36 34 0,000 0,02447333 0,03047591 ! acute inflammatory response GO:0002526 35 35 0,000 0,02518581 0,03134196 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,02518581 0,03132082 ! regulation of cellular component size GO:0032535 35 35 0,000 0,02518581 0,0312997 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,02518581 0,0312786 ! mesoderm development GO:0007498 35 35 0,000 0,02518581 0,03125754 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,02518581 0,03123651 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,02518581 0,0312155 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,02518581 0,03119452 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,02518581 0,03117357 ! inorganic anion transport GO:0015698 35 35 0,000 0,02518581 0,03115265 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,02518581 0,03113176 ! regulation of immune effector process GO:0002697 35 35 0,000 0,02518581 0,03111089 ! hydrogen transport GO:0006818 36 36 0,000 0,02589787 0,03196904 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,02589787 0,03194764 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,02589787 0,03192628 ! regulation of mitosis GO:0007088 37 36 0,000 0,02589787 0,03190493 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,02589787 0,03188362 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,02589787 0,03186234 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,02589787 0,03184108 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,02589787 0,03181985 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,02589787 0,03179866 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,02589787 0,03177748 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,02589787 0,03175634 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,02589787 0,03173523 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,02589787 0,03171414 ! gonad development GO:0008406 36 36 0,000 0,02589787 0,03169308 ! regulation of lipase activity GO:0060191 36 36 0,000 0,02589787 0,03167205 ! activation of immune response GO:0002253 36 36 0,000 0,02589787 0,03165105 ! coagulation GO:0050817 39 36 0,000 0,02589787 0,03163007 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,02660952 0,03247771 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,02660952 0,03245622 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,02660952 0,03243475 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,02660952 0,03241332 ! response to drug GO:0042493 37 37 0,000 0,02660952 0,03239191 ! lung development GO:0030324 38 37 0,000 0,02660952 0,03237053 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,02660952 0,03234917 ! eye development GO:0001654 37 37 0,000 0,02660952 0,03232785 ! negative regulation of growth GO:0045926 37 37 0,000 0,02660952 0,03230655 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,02660952 0,03228528 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,02660952 0,03226404 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,02660952 0,03224283 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,02660952 0,03222165 ! adaptive immune response GO:0002250 37 37 0,000 0,02660952 0,03220049 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,02732075 0,03303947 ! neurotransmitter transport GO:0006836 40 38 0,000 0,02732075 0,0330178 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,02732075 0,03299616 ! exocytosis GO:0006887 40 38 0,000 0,02732075 0,03297455 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,02732075 0,03295297 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,02732075 0,03293142 ! chromosome segregation GO:0007059 38 38 0,000 0,02732075 0,0329099 ! urogenital system development GO:0001655 38 38 0,000 0,02732075 0,0328884 ! hexose catabolic process GO:0019320 38 38 0,000 0,02732075 0,03286694 ! RNA elongation GO:0006354 38 38 0,000 0,02732075 0,0328455 ! meiotic cell cycle GO:0051321 38 38 0,000 0,02732075 0,03282408 ! axon guidance GO:0007411 39 38 0,000 0,02732075 0,0328027 ! regulation of neurological system process GO:0031644 38 38 0,000 0,02732075 0,03278134 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,02732075 0,03276002 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,02732075 0,03273872 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,02803157 0,03356867 ! hemostasis GO:0007599 42 39 0,000 0,02803157 0,03354687 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,02803157 0,0335251 ! activation of MAPK activity GO:0000187 39 39 0,000 0,02803157 0,03350336 ! respiratory tube development GO:0030323 40 39 0,000 0,02803157 0,03348164 ! response to unfolded protein GO:0006986 39 39 0,000 0,02803157 0,03345996 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,02803157 0,0334383 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,02803157 0,03341667 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,02803157 0,03339507 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,02803157 0,0333735 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,02803157 0,03335195 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,02803157 0,03333044 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,02803157 0,03330895 ! respiratory system development GO:0060541 40 39 0,000 0,02803157 0,03328748 ! developmental maturation GO:0021700 39 39 0,000 0,02803157 0,03326605 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,02803157 0,03324464 ! limb development GO:0060173 39 39 0,000 0,02803157 0,03322326 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,02803157 0,03320191 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,02803157 0,03318059 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,02874197 0,03399964 ! DNA catabolic process GO:0006308 41 40 0,000 0,02874197 0,03397783 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,02874197 0,03395605 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,02874197 0,0339343 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,02874197 0,03391258 ! organelle localization GO:0051640 41 40 0,000 0,02874197 0,03389088 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,02945195 0,03470585 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,02945195 0,03468367 ! amine catabolic process GO:0009310 42 41 0,000 0,02945195 0,03466152 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,02945195 0,0346394 ! regulation of caspase activity GO:0043281 41 41 0,000 0,02945195 0,03461731 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,02945195 0,03459525 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,02945195 0,03457321 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,02945195 0,03455121 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,02945195 0,03452923 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,03016152 0,03533864 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,03016152 0,03531619 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,03016152 0,03529376 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,03016152 0,03527137 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,03016152 0,035249 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,03016152 0,03522667 ! protein ubiquitination GO:0016567 43 42 0,000 0,03016152 0,03520436 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,03016152 0,03518207 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,03016152 0,03515982 ! forebrain development GO:0030900 43 42 0,000 0,03016152 0,0351376 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,03016152 0,0351154 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,03016152 0,03509323 ! reproductive structure development GO:0048608 43 43 0,000 0,03087067 0,03589568 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,03087067 0,03587304 ! mitochondrion organization GO:0007005 44 43 0,000 0,03087067 0,03585044 ! alcohol catabolic process GO:0046164 43 43 0,000 0,03087067 0,03582786 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,03087067 0,03580532 ! humoral immune response GO:0006959 44 44 0,000 0,03157941 0,03660431 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,03157941 0,0365813 ! mRNA transport GO:0051028 44 44 0,000 0,03157941 0,03655833 ! protein import into nucleus GO:0006606 44 44 0,000 0,03157941 0,03653538 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,03157941 0,03651246 ! vitamin metabolic process GO:0006766 44 44 0,000 0,03157941 0,03648956 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,03157941 0,0364667 ! amine biosynthetic process GO:0009309 46 45 0,000 0,03228773 0,0372613 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,03228773 0,03723798 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,03228773 0,03721469 ! regulation of DNA binding GO:0051101 47 45 0,000 0,03228773 0,03719143 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,03228773 0,0371682 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,03228773 0,037145 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,03228773 0,03712183 ! nuclear import GO:0051170 45 45 0,000 0,03228773 0,03709869 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,03228773 0,03707557 ! protein processing GO:0016485 45 45 0,000 0,03228773 0,03705249 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,03299564 0,0378413 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,03299564 0,03781777 ! tube morphogenesis GO:0035239 47 46 0,000 0,03299564 0,03779426 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,03299564 0,03777079 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,03299564 0,03774734 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,03299564 0,03772393 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,03299564 0,03770054 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,03299564 0,03767718 ! regulation of membrane potential GO:0042391 46 46 0,000 0,03299564 0,03765385 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,03370314 0,03843743 ! regulation of blood pressure GO:0008217 48 47 0,000 0,03370314 0,03841366 ! sex differentiation GO:0007548 47 47 0,000 0,03370314 0,03838992 ! amine transport GO:0015837 47 47 0,000 0,03370314 0,0383662 ! rhythmic process GO:0048511 47 47 0,000 0,03370314 0,03834252 ! regulation of catabolic process GO:0009894 48 47 0,000 0,03370314 0,03831887 ! calcium ion transport GO:0006816 48 48 0,000 0,03441022 0,03909867 ! actin filament organization GO:0007015 50 48 0,000 0,03441022 0,03907458 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,03441022 0,03905051 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,03441022 0,03902648 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,03441022 0,03900248 ! protein localization in nucleus GO:0034504 48 48 0,000 0,03441022 0,03897851 ! DNA recombination GO:0006310 48 48 0,000 0,03441022 0,03895457 ! leukocyte differentiation GO:0002521 50 49 0,000 0,03511689 0,03973016 ! ossification GO:0001503 50 49 0,000 0,03511689 0,03970578 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,03511689 0,03968144 ! cell cycle arrest GO:0007050 49 49 0,000 0,03511689 0,03965712 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,03511689 0,03963284 ! divalent metal ion transport GO:0070838 49 49 0,000 0,03511689 0,03960858 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,03511689 0,03958436 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,03511689 0,03956016 ! response to bacterium GO:0009617 50 49 0,000 0,03511689 0,03953599 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,03511689 0,03951186 ! regulation of ligase activity GO:0051340 50 49 0,000 0,03511689 0,03948775 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,03511689 0,03946367 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,03511689 0,03943962 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,03582314 0,04020831 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,03582314 0,04018384 ! negative regulation of transport GO:0051051 51 50 0,000 0,03582314 0,0401594 ! chromatin assembly GO:0031497 50 50 0,000 0,03582314 0,04013498 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,03582314 0,0401106 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,03582314 0,04008625 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,03582314 0,04006192 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,03582314 0,04003763 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,03582314 0,04001336 ! transcription initiation GO:0006352 50 50 0,000 0,03582314 0,03998913 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,03582314 0,03996492 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,03582314 0,03994074 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,03652898 0,04070309 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,03652898 0,0406785 ! positive regulation of immune response GO:0050778 51 51 0,000 0,03652898 0,04065393 ! rRNA metabolic process GO:0016072 51 51 0,000 0,03652898 0,0406294 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,03652898 0,04060489 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,03652898 0,04058042 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,03652898 0,04055597 ! protein maturation GO:0051604 51 51 0,000 0,03652898 0,04053155 ! RNA localization GO:0006403 52 52 0,000 0,03723441 0,04128942 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,03723441 0,04126459 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,03723441 0,04123979 ! cell fate commitment GO:0045165 52 52 0,000 0,03723441 0,04121502 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,03723441 0,04119028 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,03723441 0,04116557 ! response to light stimulus GO:0009416 53 52 0,000 0,03723441 0,04114089 ! sodium ion transport GO:0006814 53 53 0,000 0,03793942 0,04189476 ! tRNA metabolic process GO:0006399 53 53 0,000 0,03793942 0,04186967 ! response to hypoxia GO:0001666 53 53 0,000 0,03793942 0,04184461 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,03793942 0,04181959 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,03793942 0,04179459 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,03793942 0,04176962 ! regulation of T cell activation GO:0050863 53 53 0,000 0,03793942 0,04174469 ! regulation of protein transport GO:0051223 53 53 0,000 0,03793942 0,04171978 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,03864402 0,04246925 ! response to oxygen levels GO:0070482 55 54 0,000 0,03864402 0,04244394 ! response to virus GO:0009615 54 54 0,000 0,03864402 0,04241866 ! hormone metabolic process GO:0042445 55 54 0,000 0,03864402 0,04239341 ! sulfur metabolic process GO:0006790 55 54 0,000 0,03864402 0,04236819 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,03864402 0,042343 ! nucleosome organization GO:0034728 55 55 0,000 0,03934821 0,04308897 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,03934821 0,04306339 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,03934821 0,04303783 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,03934821 0,0430123 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,03934821 0,04298681 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,04005198 0,04372974 ! reproductive developmental process GO:0003006 56 56 0,000 0,04005198 0,04370385 ! extracellular structure organization GO:0043062 56 56 0,000 0,04005198 0,04367799 ! regulation of nervous system development GO:0051960 57 56 0,000 0,04005198 0,04365216 ! regulation of binding GO:0051098 60 57 0,000 0,04075534 0,04439249 ! ATP metabolic process GO:0046034 57 57 0,000 0,04075534 0,04436627 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,04075534 0,04434008 ! regulation of protein localization GO:0032880 58 57 0,000 0,04075534 0,04431392 ! innate immune response GO:0045087 58 58 0,000 0,04145829 0,04505167 ! dephosphorylation GO:0016311 60 59 0,000 0,04216083 0,0457881 ! carboxylic acid transport GO:0046942 59 59 0,000 0,04216083 0,04576113 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,04216083 0,0457342 ! regulation of cell development GO:0060284 60 59 0,000 0,04216083 0,0457073 ! sterol metabolic process GO:0016125 59 59 0,000 0,04216083 0,04568043 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,04216083 0,04565359 ! protein localization in organelle GO:0033365 59 59 0,000 0,04216083 0,04562678 ! immune effector process GO:0002252 59 59 0,000 0,04216083 0,0456 ! potassium ion transport GO:0006813 60 60 0,000 0,04286295 0,04633221 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,04286295 0,04630505 ! protein polymerization GO:0051258 65 60 0,000 0,04286295 0,04627793 ! cellular respiration GO:0045333 62 61 0,000 0,04356467 0,04700801 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,04356467 0,0469805 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,04356467 0,04695303 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,04356467 0,04692559 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,04356467 0,04689818 ! lipid transport GO:0006869 62 62 0,000 0,04426597 0,04762532 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,04426597 0,04759754 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,04426597 0,04756978 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,04426597 0,04754206 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,04426597 0,04751437 ! protein import GO:0017038 62 62 0,000 0,04426597 0,04748672 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,04426597 0,04745909 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,04426597 0,0474315 ! regulation of secretion GO:0051046 65 63 0,000 0,04496686 0,04815452 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,04496686 0,04812655 ! glucose metabolic process GO:0006006 63 63 0,000 0,04496686 0,04809862 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,04496686 0,04807072 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,04496686 0,04804285 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,04566734 0,04876298 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,04566734 0,04873474 ! angiogenesis GO:0001525 65 64 0,000 0,04566734 0,04870654 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,04566734 0,04867837 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,04566734 0,04865023 ! anion transport GO:0006820 65 65 0,000 0,04636741 0,04936749 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,04636741 0,04933899 ! regulation of hormone levels GO:0010817 66 65 0,000 0,04636741 0,04931052 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,04706706 0,05002572 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,04706706 0,04999689 ! DNA packaging GO:0006323 66 66 0,000 0,04706706 0,04996809 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,04706706 0,04993932 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,04706706 0,04991059 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,04706706 0,04988188 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,04776631 0,05059386 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,04776631 0,05056479 ! muscle contraction GO:0006936 67 67 0,000 0,04776631 0,05053577 ! striated muscle tissue development GO:0014706 69 67 0,000 0,04776631 0,05050677 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,04776631 0,05047781 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,04776631 0,05044889 ! response to radiation GO:0009314 70 68 0,000 0,04846515 0,05115765 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,04846515 0,05112837 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,04846515 0,05109912 ! regulation of cell size GO:0008361 68 68 0,000 0,04846515 0,0510699 ! regulation of translation GO:0006417 69 69 0,000 0,04916357 0,05177626 ! sensory perception of sound GO:0007605 71 69 0,000 0,04916357 0,05174669 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,04916357 0,05171716 ! response to nutrient levels GO:0031667 69 69 0,000 0,04916357 0,05168766 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,04916357 0,05165819 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,04916357 0,05162875 ! positive regulation of transport GO:0051050 71 70 0,000 0,04986159 0,05233195 ! cell part morphogenesis GO:0032990 75 70 0,000 0,04986159 0,05230216 ! wound healing GO:0042060 74 70 0,000 0,04986159 0,05227241 ! muscle tissue development GO:0060537 72 70 0,000 0,04986159 0,0522427 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,04986159 0,05221301 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,05055919 0,05291345 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,05055919 0,05288342 ! regulation of cell migration GO:0030334 71 71 0,000 0,05055919 0,05285343 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,05055919 0,05282346 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,05055919 0,05279353 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,05055919 0,05276364 ! regulation of cell activation GO:0050865 71 71 0,000 0,05055919 0,05273378 ! secretion by cell GO:0032940 75 72 0,000 0,05125639 0,05343072 ! muscle system process GO:0003012 72 72 0,000 0,05125639 0,05340052 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,05125639 0,05337035 ! sensory organ development GO:0007423 72 72 0,000 0,05125639 0,05334021 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,05125639 0,05331011 ! regulation of cytokine production GO:0001817 72 72 0,000 0,05125639 0,05328005 ! electron transport chain GO:0022900 75 74 0,000 0,05264955 0,05469736 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,05264955 0,05466655 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,05334552 0,05535799 ! response to oxidative stress GO:0006979 76 75 0,000 0,05334552 0,05532684 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,05334552 0,05529572 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,05404107 0,05598522 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,05404107 0,05595376 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,05473622 0,0566417 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,05473622 0,05660991 ! regulation of protein modification process GO:0031399 79 78 0,000 0,05543096 0,05729628 ! microtubule-based movement GO:0007018 82 78 0,000 0,05543096 0,05726416 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,05543096 0,05723208 ! metal ion homeostasis GO:0055065 78 78 0,000 0,05543096 0,05720004 ! regulation of immune response GO:0050776 78 78 0,000 0,05543096 0,05716803 ! regulation of locomotion GO:0040012 79 79 0,000 0,0561253 0,05785174 ! nuclear transport GO:0051169 79 79 0,000 0,0561253 0,05781941 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 0,000 0,0561253 0,05778711 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,05681922 0,05846891 ! neuron projection development GO:0031175 85 80 0,000 0,05681922 0,05843628 ! MAPKKK cascade GO:0000165 82 81 0,000 0,05751273 0,05911655 ! tube development GO:0035295 83 81 0,000 0,05751273 0,05908359 ! lymphocyte activation GO:0046649 82 81 0,000 0,05751273 0,05905068 ! lipid catabolic process GO:0016042 82 81 0,000 0,05751273 0,0590178 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,05889854 0,06040624 ! ncRNA processing GO:0034470 83 83 0,000 0,05889854 0,06037264 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,05889854 0,06033908 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,05959083 0,06101439 ! regulation of cellular localization GO:0060341 86 85 0,000 0,06028272 0,06168853 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,06028272 0,0616543 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,06028272 0,0616201 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,06028272 0,06158595 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,06097419 0,06225786 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,06097419 0,06222339 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,06097419 0,06218895 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,06097419 0,06215456 ! heart development GO:0007507 90 87 0,000 0,06166526 0,06282426 ! male gamete generation GO:0048232 90 88 0,000 0,06235593 0,0634928 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,06235593 0,06345774 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,06235593 0,06342272 ! chemotaxis GO:0006935 90 89 0,000 0,06304618 0,06408942 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,06304618 0,06405409 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,06373603 0,06471929 ! brain development GO:0007420 91 90 0,000 0,06373603 0,06468365 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,06442548 0,06534736 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,06442548 0,06531141 ! DNA replication GO:0006260 91 91 0,000 0,06442548 0,06527551 ! visual perception GO:0007601 93 92 0,000 0,06511451 0,06593739 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,06511451 0,06590118 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,06511451 0,06586501 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,06511451 0,06582888 ! tissue morphogenesis GO:0048729 94 93 0,000 0,06580314 0,06648859 ! regulation of response to stress GO:0080134 97 94 0,000 0,06649137 0,06714717 ! blood vessel development GO:0001568 95 94 0,000 0,06649137 0,0671104 ! pattern specification process GO:0007389 96 94 0,000 0,06649137 0,06707367 ! epidermis development GO:0008544 94 94 0,000 0,06649137 0,06703698 ! cofactor metabolic process GO:0051186 95 94 0,000 0,06649137 0,06700032 ! regulation of cell growth GO:0001558 97 96 0,000 0,0678666 0,06834872 ! vasculature development GO:0001944 97 96 0,000 0,0678666 0,06831139 ! endocytosis GO:0006897 99 98 0,000 0,06924022 0,06965596 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,06924022 0,06961796 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,06924022 0,06958 ! blood circulation GO:0008015 99 98 0,000 0,06924022 0,06954208 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,06924022 0,0695042 ! anti-apoptosis GO:0006916 100 99 0,000 0,06992641 0,07015481 ! ectoderm development GO:0007398 99 99 0,000 0,06992641 0,07011664 ! response to hormone stimulus GO:0009725 102 100 0,000 0,07061221 0,0707658 ! muscle organ development GO:0007517 102 100 0,000 0,07061221 0,07072734 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,07061221 0,07068892 ! response to other organism GO:0051707 101 100 0,000 0,07061221 0,07065054 ! hemopoiesis GO:0030097 104 100 0,000 0,07061221 0,07061221