pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/2580-3-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 1,535E-05 0,03529879 ! protein refolding GO:0042026 13 6 1,000 1,86E-05 0,02139057 ! response to UV GO:0009411 75 46 2,000 1,884E-05 0,0144414 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 2,575E-05 0,0148047 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,602E-05 0,0119705 ! regulation of defense response to virus by virus GO:0050690 16 7 1,000 2,602E-05 9,975E-03 ! outer mitochondrial membrane organization GO:0007008 12 7 1,000 2,602E-05 8,55E-03 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! mast cell activation GO:0045576 9 7 1,000 2,602E-05 7,482E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 3,467E-05 8,861E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 3,467E-05 7,975E-03 ! chaperone-mediated protein complex assembly GO:0051131 12 8 1,000 3,467E-05 7,25E-03 ! thymus development GO:0048538 15 9 1,000 4,455E-05 8,539E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 5,565E-05 9,845E-03 ! response to metal ion GO:0010038 103 70 2,000 6,675E-05 0,01096557 ! T cell homeostasis GO:0043029 20 11 1,000 6,797E-05 0,01042178 ! response to inorganic substance GO:0010035 115 75 2,000 8,204E-05 0,01179274 ! response to unfolded protein GO:0006986 99 76 2,000 8,535E-05 0,01154675 ! lymphocyte homeostasis GO:0002260 24 13 1,000 9,626E-05 0,01229975 ! response to protein stimulus GO:0051789 111 81 2,000 1,032E-04 0,01249299 ! regulation of defense response to virus GO:0050688 24 14 1,000 1,122E-04 0,01290587 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 1,233E-04 0,01350863 ! interphase GO:0051325 159 88 2,000 1,321E-04 0,01380632 ! cellular response to unfolded protein GO:0034620 19 16 1,000 1,478E-04 0,0147786 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 1,674E-04 0,01604019 ! response to light stimulus GO:0009416 153 96 2,000 1,709E-04 0,01572709 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 2,102E-04 0,01859124 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 2,334E-04 0,01987822 ! positive regulation of B cell activation GO:0050871 31 20 1,000 2,334E-04 0,01916828 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 2,577E-04 0,02044141 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 2,577E-04 0,01976003 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 2,577E-04 0,01912261 ! regulation of multi-organism process GO:0043900 32 21 1,000 2,577E-04 0,01852503 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 2,833E-04 0,01974648 ! leukocyte homeostasis GO:0001776 33 22 1,000 2,833E-04 0,0191657 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 3,101E-04 0,02037727 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 3,101E-04 0,01981124 ! regulation of response to biotic stimulus GO:0002831 35 23 1,000 3,101E-04 0,0192758 ! fat cell differentiation GO:0045444 37 24 1,000 3,38E-04 0,02046073 ! mitochondrial membrane organization GO:0007006 39 24 1,000 3,38E-04 0,0199361 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 3,672E-04 0,02111344 GO:0045936|negative regulation of phosphate metabolic process, ! myeloid leukocyte activation GO:0002274 39 28 1,000 4,617E-04 0,02590072 ! regulation of B cell activation GO:0050864 42 28 1,000 4,617E-04 0,02528403 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 7,233E-04 0,0386872 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to calcium ion GO:0051592 58 40 1,000 9,449E-04 0,04939372 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 9,449E-04 0,04829608 ! mitochondrial transport GO:0006839 60 42 1,000 1,042E-03 0,05208104 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 1,143E-03 0,05592837 ! positive regulation of cell cycle GO:0045787 77 45 1,000 1,195E-03 0,05727105 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 1,303E-03 0,0611752 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 1,911E-03 0,08790887 ! negative regulation of kinase activity GO:0033673 100 58 1,000 1,978E-03 0,08920207 ! homeostasis of number of cells GO:0048872 84 61 1,000 2,185E-03 0,09665571 ! negative regulation of transferase activity GO:0051348 105 61 1,000 2,185E-03 0,09483202 ! negative regulation of cell growth GO:0030308 106 62 1,000 2,257E-03 0,09611254 ! negative regulation of cell size GO:0045792 108 64 1,000 2,402E-03 0,1004651 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 2,402E-03 0,09867108 ! regulation of immune effector process GO:0002697 101 66 1,000 2,553E-03 0,10300184 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 2,866E-03 0,11365593 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 3,029E-03 0,11809108 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 104 73 1,000 3,112E-03 0,11931226 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 3,197E-03 0,12053367 ! negative regulation of growth GO:0045926 123 75 1,000 3,282E-03 0,12175523 ! positive regulation of protein modification process GO:0031401 107 78 1,000 3,544E-03 0,12940149 ! positive regulation of cell activation GO:0050867 120 81 1,000 3,816E-03 0,13715064 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 117 84 1,000 4,098E-03 0,14499574 ! cell cycle arrest GO:0007050 150 86 1,000 4,29E-03 0,14951692 ! in utero embryonic development GO:0001701 147 96 1,000 5,316E-03 0,18250137 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 5,708E-03 0,19305617 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 5,708E-03 0,19025826 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 5,708E-03 0,18754028 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 5,708E-03 0,18489887 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 5,708E-03 0,18233083 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,708E-03 0,17983315 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 5,708E-03 0,17740297 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 5,708E-03 0,1750376 ! sleep GO:0030431 11 5 0,000 5,708E-03 0,17273447 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,708E-03 0,17049116 ! nucleotide-sugar transport GO:0015780 8 5 0,000 5,708E-03 0,16830538 ! regulation of interferon-beta production GO:0032648 5 5 0,000 5,708E-03 0,16617493 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 5,708E-03 0,16409775 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 5,708E-03 0,16207185 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 5,708E-03 0,16009536 ! tongue development GO:0043586 6 5 0,000 5,708E-03 0,1581665 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 5,708E-03 0,15628357 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 5,708E-03 0,15444494 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 5,708E-03 0,15264907 ! cobalt ion transport GO:0006824 9 5 0,000 5,708E-03 0,15089448 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 5,708E-03 0,14917977 ! SMAD protein complex assembly GO:0007183 9 5 0,000 5,708E-03 0,14750359 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 5,708E-03 0,14586466 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 5,708E-03 0,14426175 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 5,708E-03 0,14269369 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 5,708E-03 0,14115935 ! embryonic camera-type eye development GO:0031076 8 5 0,000 5,708E-03 0,13965766 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 5,708E-03 0,13818758 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 5,708E-03 0,13674812 ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,708E-03 0,13533835 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 5,708E-03 0,13395734 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 5,708E-03 0,13260424 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 5,708E-03 0,1312782 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 5,708E-03 0,12997841 ! positive regulation of histone modification GO:0031058 5 5 0,000 5,708E-03 0,12870411 ! malate metabolic process GO:0006108 7 5 0,000 5,708E-03 0,12745456 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 5,708E-03 0,12622904 ! behavioral response to pain GO:0048266 7 5 0,000 5,708E-03 0,12502685 ! clathrin coat assembly GO:0048268 11 5 0,000 5,708E-03 0,12384736 ! phototransduction, visible light GO:0007603 6 5 0,000 5,708E-03 0,1226899 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,708E-03 0,12155389 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 5,708E-03 0,12043871 ! mating behavior GO:0007617 6 5 0,000 5,708E-03 0,11934382 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 5,708E-03 0,11826865 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 5,708E-03 0,11721268 ! rhythmic behavior GO:0007622 12 5 0,000 5,708E-03 0,1161754 ! copulation GO:0007620 7 5 0,000 5,708E-03 0,11515631 ! glial cell fate commitment GO:0021781 12 5 0,000 5,708E-03 0,11415495 ! protein maturation by protein folding GO:0022417 12 5 0,000 5,708E-03 0,11317086 ! embryonic hemopoiesis GO:0035162 10 5 0,000 5,708E-03 0,11220359 ! regulation of potassium ion transport GO:0043266 9 5 0,000 5,708E-03 0,11125271 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 5,708E-03 0,11031781 ! apoptotic cell clearance GO:0043277 13 5 0,000 5,708E-03 0,1093985 ! lipoprotein particle clearance GO:0034381 9 5 0,000 5,708E-03 0,10849438 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 5,708E-03 0,10760508 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,708E-03 0,10673024 ! response to protozoan GO:0001562 9 5 0,000 5,708E-03 0,10586951 ! positive regulation of glycolysis GO:0045821 11 5 0,000 5,708E-03 0,10502256 ! lymph vessel development GO:0001945 7 5 0,000 5,708E-03 0,10418904 ! endochondral ossification GO:0001958 12 5 0,000 5,708E-03 0,10336866 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 5,708E-03 0,10256109 ! parathyroid gland development GO:0060017 8 5 0,000 5,708E-03 0,10176604 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 5,708E-03 0,10098323 ! anagen GO:0042640 6 5 0,000 5,708E-03 0,10021236 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 5,708E-03 0,09945318 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 5,708E-03 0,09870541 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 5,708E-03 0,0979688 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 5,708E-03 0,09724311 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 5,708E-03 0,09652809 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 5,708E-03 0,0958235 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 5,708E-03 0,09512913 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 5,708E-03 0,09444475 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 5,708E-03 0,09377014 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 5,708E-03 0,0931051 ! cardiac muscle fiber development GO:0048739 7 5 0,000 5,708E-03 0,09244943 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 5,708E-03 0,09180293 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 5,708E-03 0,09116541 ! neutrophil mediated immunity GO:0002446 6 5 0,000 5,708E-03 0,09053669 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,708E-03 0,08991657 ! ovulation GO:0030728 6 5 0,000 5,708E-03 0,0893049 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 5,708E-03 0,08870148 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 5,708E-03 0,08810617 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 5,708E-03 0,0875188 ! response to pH GO:0009268 9 5 0,000 5,708E-03 0,0869392 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 5,708E-03 0,08636723 ! proline biosynthetic process GO:0006561 6 5 0,000 5,708E-03 0,08580274 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 5,708E-03 0,08524558 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 5,708E-03 0,08469561 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 5,708E-03 0,08415269 ! polyol catabolic process GO:0046174 7 5 0,000 5,708E-03 0,08361669 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 5,708E-03 0,08308747 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 5,708E-03 0,0825649 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 5,708E-03 0,08204887 ! sister chromatid cohesion GO:0007062 9 5 0,000 5,708E-03 0,08153925 ! nerve growth factor processing GO:0032455 7 5 0,000 5,708E-03 0,08103592 ! urea metabolic process GO:0019627 6 5 0,000 5,708E-03 0,08053877 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 5,708E-03 0,08004768 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 5,708E-03 0,07956254 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 5,708E-03 0,07908325 ! neutrophil activation GO:0042119 5 5 0,000 5,708E-03 0,0786097 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 5,708E-03 0,07814178 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 5,708E-03 0,07767941 ! response to food GO:0032094 5 5 0,000 5,708E-03 0,07722247 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 5,708E-03 0,07677088 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,708E-03 0,07632453 ! paraxial mesoderm development GO:0048339 9 5 0,000 5,708E-03 0,07588335 ! forebrain neuron development GO:0021884 7 5 0,000 5,708E-03 0,07544724 ! melanosome organization GO:0032438 7 5 0,000 5,708E-03 0,07501611 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 5,708E-03 0,07458988 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,708E-03 0,07416847 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 5,708E-03 0,0737518 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,708E-03 0,07333977 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 5,708E-03 0,07293233 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 5,708E-03 0,07252939 ! nucleoside transport GO:0015858 6 5 0,000 5,708E-03 0,07213088 ! nucleoside salvage GO:0043174 7 5 0,000 5,708E-03 0,07173672 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 5,708E-03 0,07134685 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,708E-03 0,07096119 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 5,708E-03 0,07057968 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 5,708E-03 0,07020224 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 5,708E-03 0,06982883 ! early endosome to late endosome transport GO:0045022 11 5 0,000 5,708E-03 0,06945936 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,708E-03 0,06909379 ! depyrimidination GO:0045008 8 5 0,000 5,708E-03 0,06873204 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 5,708E-03 0,06837406 ! 5S class rRNA transcription GO:0042791 8 5 0,000 5,708E-03 0,06801979 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 5,708E-03 0,06766917 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,708E-03 0,06732215 ! neuronal ion channel clustering GO:0045161 7 5 0,000 5,708E-03 0,06697867 ! sodium ion homeostasis GO:0055078 6 5 0,000 5,708E-03 0,06663868 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 5,708E-03 0,06630212 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 5,708E-03 0,06596894 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 5,708E-03 0,0656391 ! monocyte differentiation GO:0030224 8 5 0,000 5,708E-03 0,06531254 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 5,708E-03 0,06498921 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 5,708E-03 0,06466906 ! centrosome duplication GO:0051298 5 5 0,000 5,708E-03 0,06435206 ! response to UV-C GO:0010225 6 5 0,000 5,708E-03 0,06403814 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 5,708E-03 0,06372728 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 5,708E-03 0,06341942 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 5,708E-03 0,06311452 ! regulation of dendrite development GO:0050773 12 5 0,000 5,708E-03 0,06281253 ! peptidyl-arginine modification GO:0018195 7 5 0,000 5,708E-03 0,06251343 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,708E-03 0,06221715 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 5,708E-03 0,06192368 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 5,708E-03 0,06163296 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 5,708E-03 0,06134495 ! regulation of dopamine secretion GO:0014059 12 5 0,000 5,708E-03 0,06105963 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 5,708E-03 0,06077694 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 5,708E-03 0,06049686 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 5,708E-03 0,06021936 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 5,708E-03 0,05994438 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 5,708E-03 0,05967191 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 5,708E-03 0,0594019 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 5,708E-03 0,05913432 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 5,708E-03 0,05886915 ! neural tube patterning GO:0021532 6 5 0,000 5,708E-03 0,05860634 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 5,708E-03 0,05834587 ! histone demethylation GO:0016577 9 5 0,000 5,708E-03 0,0580877 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 5,708E-03 0,0578318 ! regulation of sterol transport GO:0032371 7 5 0,000 5,708E-03 0,05757816 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 5,708E-03 0,05732672 ! enteric nervous system development GO:0048484 8 5 0,000 5,708E-03 0,05707748 ! establishment of planar polarity GO:0001736 6 5 0,000 5,708E-03 0,05683039 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,708E-03 0,05658543 ! muscle cell proliferation GO:0033002 8 5 0,000 5,708E-03 0,05634257 ! transcription termination GO:0006353 8 5 0,000 5,708E-03 0,05610179 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 5,708E-03 0,05586306 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 5,708E-03 0,05562635 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 5,708E-03 0,05539164 ! regulation of respiratory burst GO:0060263 8 5 0,000 5,708E-03 0,05515891 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 5,708E-03 0,05492812 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 5,708E-03 0,05469925 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 5,708E-03 0,05447228 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 5,708E-03 0,05424719 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 5,708E-03 0,05402395 ! apical protein localization GO:0045176 6 5 0,000 5,708E-03 0,05380254 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 5,708E-03 0,05358294 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 5,708E-03 0,05336512 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,708E-03 0,05314907 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 5,708E-03 0,05293476 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 5,708E-03 0,05272217 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 5,708E-03 0,05251128 ! triglyceride catabolic process GO:0019433 6 5 0,000 5,708E-03 0,05230207 ! glial cell migration GO:0008347 10 5 0,000 5,708E-03 0,05209452 ! determination of adult lifespan GO:0008340 8 5 0,000 5,708E-03 0,05188862 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 5,708E-03 0,05168433 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 5,708E-03 0,05148165 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 5,708E-03 0,05128055 ! somatic stem cell maintenance GO:0035019 13 5 0,000 5,708E-03 0,05108101 ! cerebellar cortex formation GO:0021697 6 5 0,000 5,708E-03 0,05088302 ! neural plate development GO:0001840 6 5 0,000 5,708E-03 0,05068656 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 5,708E-03 0,05049161 ! regulation of sensory perception GO:0051931 6 5 0,000 5,708E-03 0,05029816 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 5,708E-03 0,05010618 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 5,708E-03 0,04991566 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 5,708E-03 0,04972659 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 5,708E-03 0,04953894 ! sensory cilium assembly GO:0035058 6 5 0,000 5,708E-03 0,04935271 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 5,708E-03 0,04916786 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 5,708E-03 0,0489844 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 5,708E-03 0,0488023 ! spindle assembly GO:0051225 5 5 0,000 5,708E-03 0,04862155 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 5,708E-03 0,04844214 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 5,708E-03 0,04826404 ! protein amino acid prenylation GO:0018346 9 5 0,000 5,708E-03 0,04808725 ! organ regeneration GO:0031100 7 5 0,000 5,708E-03 0,04791175 ! NAD biosynthetic process GO:0009435 7 5 0,000 5,708E-03 0,04773753 ! carnitine metabolic process GO:0009437 5 5 0,000 5,708E-03 0,04756456 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 5,708E-03 0,04739285 ! cellular anion homeostasis GO:0030002 6 5 0,000 5,708E-03 0,04722237 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 11 6 0,000 6,846E-03 0,05643307 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 6,846E-03 0,05623153 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 6,846E-03 0,05603141 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 6,846E-03 0,05583272 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 6,846E-03 0,05563543 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 6,846E-03 0,05543953 ! regulation of helicase activity GO:0051095 11 6 0,000 6,846E-03 0,05524501 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 6,846E-03 0,05505184 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 6,846E-03 0,05486003 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 6,846E-03 0,05466954 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 6,846E-03 0,05448037 ! positive regulation of axon extension GO:0045773 8 6 0,000 6,846E-03 0,05429251 ! prostate gland development GO:0030850 9 6 0,000 6,846E-03 0,05410594 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 6,846E-03 0,05392064 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 6,846E-03 0,05373661 ! forebrain neuron differentiation GO:0021879 9 6 0,000 6,846E-03 0,05355383 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 6,846E-03 0,0533723 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 6,846E-03 0,05319198 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 6,846E-03 0,05301289 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 6,846E-03 0,05283499 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 6,846E-03 0,05265829 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 6,846E-03 0,05248276 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 6,846E-03 0,0523084 ! neuron adhesion GO:0007158 9 6 0,000 6,846E-03 0,05213519 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 6,846E-03 0,05196313 ! establishment of tissue polarity GO:0007164 7 6 0,000 6,846E-03 0,0517922 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 6,846E-03 0,05162238 ! signal peptide processing GO:0006465 8 6 0,000 6,846E-03 0,05145368 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 6,846E-03 0,05128608 ! mRNA stabilization GO:0048255 15 6 0,000 6,846E-03 0,05111957 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 6,846E-03 0,05095413 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 6,846E-03 0,05078977 GO:0016441|posttranscriptional gene silencing, ! opsonization GO:0008228 8 6 0,000 6,846E-03 0,05062645 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 6,846E-03 0,05046419 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 6,846E-03 0,05030296 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 6,846E-03 0,05014276 ! protein amino acid dealkylation GO:0008214 11 6 0,000 6,846E-03 0,04998358 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 6,846E-03 0,0498254 ! photoreceptor cell development GO:0042461 10 6 0,000 6,846E-03 0,04966823 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 6,846E-03 0,04951204 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 6,846E-03 0,04935683 ! mechanosensory behavior GO:0007638 8 6 0,000 6,846E-03 0,04920259 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 6,846E-03 0,04904931 ! negative regulation of endocytosis GO:0045806 8 6 0,000 6,846E-03 0,04889698 ! response to interferon-gamma GO:0034341 12 6 0,000 6,846E-03 0,0487456 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 6,846E-03 0,04859515 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 6,846E-03 0,04844562 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 6,846E-03 0,04829702 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 6,846E-03 0,04814932 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 6,846E-03 0,04800252 ! cGMP-mediated signaling GO:0019934 10 6 0,000 6,846E-03 0,04785662 ! activation of MAPKKK activity GO:0000185 10 6 0,000 6,846E-03 0,0477116 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 6,846E-03 0,04756745 ! thymic T cell selection GO:0045061 12 6 0,000 6,846E-03 0,04742418 ! protein lipoylation GO:0009249 10 6 0,000 6,846E-03 0,04728176 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 6,846E-03 0,0471402 ! pigment granule organization GO:0048753 11 6 0,000 6,846E-03 0,04699948 ! drug transport GO:0015893 6 6 0,000 6,846E-03 0,04685961 ! cysteine metabolic process GO:0006534 7 6 0,000 6,846E-03 0,04672056 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 6,846E-03 0,04658233 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 6,846E-03 0,04644492 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 6,846E-03 0,04630832 ! histidine metabolic process GO:0006547 6 6 0,000 6,846E-03 0,04617251 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 6,846E-03 0,04603751 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 6,846E-03 0,04590329 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 6,846E-03 0,04576985 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 6,846E-03 0,04563718 ! adenohypophysis development GO:0021984 10 6 0,000 6,846E-03 0,04550528 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 6,846E-03 0,04537414 ! hyperosmotic response GO:0006972 8 6 0,000 6,846E-03 0,04524376 ! microtubule nucleation GO:0007020 10 6 0,000 6,846E-03 0,04511412 ! ER overload response GO:0006983 7 6 0,000 6,846E-03 0,04498522 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 6,846E-03 0,04485706 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 6,846E-03 0,04472962 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 6,846E-03 0,04460291 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 6,846E-03 0,04447691 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 6,846E-03 0,04435163 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 6,846E-03 0,04422704 ! response to dietary excess GO:0002021 7 6 0,000 6,846E-03 0,04410316 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 6,846E-03 0,04397996 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 6,846E-03 0,04385746 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 6,846E-03 0,04373563 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 6,846E-03 0,04361448 ! glycerol ether catabolic process GO:0044269 8 6 0,000 6,846E-03 0,043494 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 6,846E-03 0,04337418 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 6,846E-03 0,04325502 ! neuron apoptosis GO:0051402 8 6 0,000 6,846E-03 0,04313651 ! organic alcohol transport GO:0015850 9 6 0,000 6,846E-03 0,04301865 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 6,846E-03 0,04290144 ! T cell mediated immunity GO:0002456 12 6 0,000 6,846E-03 0,04278486 ! male sex determination GO:0030238 9 6 0,000 6,846E-03 0,04266891 ! carnitine transport GO:0015879 8 6 0,000 6,846E-03 0,04255359 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 6,846E-03 0,04243889 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 6,846E-03 0,0423248 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,846E-03 0,04221133 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 6,846E-03 0,04209847 ! positive regulation of exocytosis GO:0045921 6 6 0,000 6,846E-03 0,04198621 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 6,846E-03 0,04187454 ! parturition GO:0007567 12 6 0,000 6,846E-03 0,04176347 ! negative regulation of translational initiation GO:0045947 7 6 0,000 6,846E-03 0,04165298 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 6,846E-03 0,04154308 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 6,846E-03 0,04143376 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 6,846E-03 0,04132501 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 6,846E-03 0,04121683 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 6,846E-03 0,04110921 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 6,846E-03 0,04100215 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 6,846E-03 0,04089566 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 6,846E-03 0,04078971 ! macrophage differentiation GO:0030225 10 6 0,000 6,846E-03 0,04068431 ! astrocyte development GO:0014002 14 6 0,000 6,846E-03 0,04057945 ! hyaluronan metabolic process GO:0030212 6 6 0,000 6,846E-03 0,04047513 ! purine base biosynthetic process GO:0009113 14 6 0,000 6,846E-03 0,04037135 ! interaction with symbiont GO:0051702 8 6 0,000 6,846E-03 0,0402681 ! anterograde axon cargo transport GO:0008089 8 6 0,000 6,846E-03 0,04016538 ! skeletal muscle contraction GO:0003009 6 6 0,000 6,846E-03 0,04006317 ! eating behavior GO:0042755 6 6 0,000 6,846E-03 0,03996149 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 6,846E-03 0,03986032 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 6,846E-03 0,03975967 ! response to copper ion GO:0046688 9 6 0,000 6,846E-03 0,03965951 ! DNA topological change GO:0006265 8 6 0,000 6,846E-03 0,03955987 ! response to exogenous dsRNA GO:0043330 8 6 0,000 6,846E-03 0,03946072 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 6,846E-03 0,03936207 ! establishment of melanosome localization GO:0032401 9 6 0,000 6,846E-03 0,03926391 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,846E-03 0,03916624 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 6,846E-03 0,03906905 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 6,846E-03 0,03897234 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 6,846E-03 0,03887612 ! nucleoside catabolic process GO:0009164 6 6 0,000 6,846E-03 0,03878036 ! gas homeostasis GO:0033483 11 6 0,000 6,846E-03 0,03868508 ! hair follicle maturation GO:0048820 7 6 0,000 6,846E-03 0,03859026 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 6,846E-03 0,03849591 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 6,846E-03 0,03840202 ! Schwann cell development GO:0014044 14 6 0,000 6,846E-03 0,03830858 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 6,846E-03 0,0382156 ! dendrite morphogenesis GO:0048813 9 6 0,000 6,846E-03 0,03812307 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 6,846E-03 0,03803098 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 6,846E-03 0,03793934 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 6,846E-03 0,03784814 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 6,846E-03 0,03775738 ! histone ubiquitination GO:0016574 7 6 0,000 6,846E-03 0,03766705 ! regulation of meiosis GO:0040020 10 6 0,000 6,846E-03 0,03757715 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 6,846E-03 0,03748768 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 6,846E-03 0,03739864 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 6,846E-03 0,03731002 ! regulation of mast cell activation GO:0033003 6 6 0,000 6,846E-03 0,03722181 ! membrane to membrane docking GO:0022614 12 6 0,000 6,846E-03 0,03713403 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 6,846E-03 0,03704665 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 6,846E-03 0,03695969 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 6,846E-03 0,03687313 ! receptor internalization GO:0031623 9 6 0,000 6,846E-03 0,03678698 ! neutrophil homeostasis GO:0001780 6 6 0,000 6,846E-03 0,03670123 ! coenzyme A metabolic process GO:0015936 9 6 0,000 6,846E-03 0,03661588 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,846E-03 0,03653092 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 6,846E-03 0,03644636 ! protein deubiquitination GO:0016579 8 6 0,000 6,846E-03 0,03636219 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 6,846E-03 0,0362784 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 6,846E-03 0,03619501 ! peptidyl-histidine modification GO:0018202 9 6 0,000 6,846E-03 0,03611199 ! axonal fasciculation GO:0007413 9 6 0,000 6,846E-03 0,03602935 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 6,846E-03 0,03594709 ! thiamin metabolic process GO:0006772 6 6 0,000 6,846E-03 0,03586521 ! midbrain development GO:0030901 6 6 0,000 6,846E-03 0,0357837 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 6,846E-03 0,03570256 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 6,846E-03 0,03562178 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 6,846E-03 0,03554137 ! progesterone metabolic process GO:0042448 8 6 0,000 6,846E-03 0,03546132 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 6,846E-03 0,03538163 ! glycolipid catabolic process GO:0019377 13 6 0,000 6,846E-03 0,0353023 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 6,846E-03 0,03522333 ! positive regulation of glucose import GO:0046326 6 6 0,000 6,846E-03 0,0351447 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 6,846E-03 0,03506643 ! adult feeding behavior GO:0008343 6 6 0,000 6,846E-03 0,03498851 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 6,846E-03 0,03491093 ! blastocyst growth GO:0001832 15 6 0,000 6,846E-03 0,03483369 ! pigment granule transport GO:0051904 12 6 0,000 6,846E-03 0,03475679 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 6,846E-03 0,03468024 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 6,846E-03 0,03460402 ! catecholamine transport GO:0051937 7 6 0,000 6,846E-03 0,03452813 ! organ or tissue specific immune response GO:0002251 7 6 0,000 6,846E-03 0,03445258 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 6,846E-03 0,03437735 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 6,846E-03 0,03430246 ! negative regulation of B cell activation GO:0050869 9 6 0,000 6,846E-03 0,03422789 ! protein prenylation GO:0018342 10 6 0,000 6,846E-03 0,03415364 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 6,846E-03 0,03407971 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 6,846E-03 0,03400611 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 6,846E-03 0,03393282 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 6,846E-03 0,03385984 ! positive regulation of coagulation GO:0050820 11 6 0,000 6,846E-03 0,03378718 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 7,982E-03 0,03931261 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 7,982E-03 0,03922861 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 7,982E-03 0,03914497 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 7,982E-03 0,03906168 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 7,982E-03 0,03897875 ! synaptonemal complex assembly GO:0007130 10 7 0,000 7,982E-03 0,03889616 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 7,982E-03 0,03881393 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,982E-03 0,03873205 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 7,982E-03 0,0386505 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 7,982E-03 0,03856931 ! reproductive behavior GO:0019098 12 7 0,000 7,982E-03 0,03848845 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 7,982E-03 0,03840793 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 7,982E-03 0,03832774 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 7,982E-03 0,0382479 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 7,982E-03 0,03816838 ! oligopeptide transport GO:0006857 11 7 0,000 7,982E-03 0,03808919 ! protein amino acid sulfation GO:0006477 9 7 0,000 7,982E-03 0,03801033 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 7,982E-03 0,0379318 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 7,982E-03 0,03785359 ! RNA methylation GO:0001510 11 7 0,000 7,982E-03 0,0377757 ! pericardium development GO:0060039 8 7 0,000 7,982E-03 0,03769813 ! macrophage chemotaxis GO:0048246 10 7 0,000 7,982E-03 0,03762088 ! fibril organization GO:0043206 13 7 0,000 7,982E-03 0,03754395 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 7,982E-03 0,03746733 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 7,982E-03 0,03739102 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 7,982E-03 0,03731502 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 7,982E-03 0,03723933 ! lipoprotein transport GO:0042953 9 7 0,000 7,982E-03 0,03716395 ! cerebral cortex cell migration GO:0021795 11 7 0,000 7,982E-03 0,03708887 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 7,982E-03 0,03701409 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 7,982E-03 0,03693962 ! estrogen metabolic process GO:0008210 14 7 0,000 7,982E-03 0,03686544 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 7,982E-03 0,03679156 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 7,982E-03 0,03671798 ! chemosensory behavior GO:0007635 9 7 0,000 7,982E-03 0,03664469 ! microtubule bundle formation GO:0001578 8 7 0,000 7,982E-03 0,03657169 ! T-helper 1 type immune response GO:0042088 11 7 0,000 7,982E-03 0,03649899 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 7,982E-03 0,03642657 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 7,982E-03 0,03635444 ! leukocyte degranulation GO:0043299 10 7 0,000 7,982E-03 0,03628259 ! bile acid and bile salt transport GO:0015721 9 7 0,000 7,982E-03 0,03621103 ! reflex GO:0060004 12 7 0,000 7,982E-03 0,03613974 ! positive regulation of isotype switching GO:0045830 15 7 0,000 7,982E-03 0,03606874 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 7,982E-03 0,03599802 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,982E-03 0,03592757 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 7,982E-03 0,0358574 ! glycerolipid catabolic process GO:0046503 9 7 0,000 7,982E-03 0,0357875 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,982E-03 0,03571788 ! spinal cord patterning GO:0021511 7 7 0,000 7,982E-03 0,03564852 ! hemoglobin metabolic process GO:0020027 10 7 0,000 7,982E-03 0,03557944 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 7,982E-03 0,03551062 ! adrenal gland development GO:0030325 17 7 0,000 7,982E-03 0,03544207 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 7,982E-03 0,03537378 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 7,982E-03 0,03530575 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 7,982E-03 0,03523798 ! endosome organization GO:0007032 10 7 0,000 7,982E-03 0,03517048 ! thyroid hormone generation GO:0006590 11 7 0,000 7,982E-03 0,03510323 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 7,982E-03 0,03503624 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 7,982E-03 0,0349695 ! regulation of pigmentation during development GO:0048070 15 7 0,000 7,982E-03 0,03490302 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 7,982E-03 0,03483679 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 7,982E-03 0,03477081 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 7,982E-03 0,03470508 ! galactose metabolic process GO:0006012 10 7 0,000 7,982E-03 0,0346396 ! vesicle fusion GO:0006906 15 7 0,000 7,982E-03 0,03457437 ! intracellular pH reduction GO:0051452 10 7 0,000 7,982E-03 0,03450938 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 7,982E-03 0,03444463 ! organ growth GO:0035265 11 7 0,000 7,982E-03 0,03438013 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 7,982E-03 0,03431587 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 7,982E-03 0,03425185 ! Rac protein signal transduction GO:0016601 7 7 0,000 7,982E-03 0,03418806 ! retinol metabolic process GO:0042572 9 7 0,000 7,982E-03 0,03412452 ! behavioral fear response GO:0001662 13 7 0,000 7,982E-03 0,03406121 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 7,982E-03 0,03399813 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 7,982E-03 0,03393529 ! rRNA modification GO:0000154 12 7 0,000 7,982E-03 0,03387267 ! protein heterooligomerization GO:0051291 10 7 0,000 7,982E-03 0,03381029 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 7,982E-03 0,03374814 ! response to UV-B GO:0010224 11 7 0,000 7,982E-03 0,03368622 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 7,982E-03 0,03362452 ! protein retention in ER lumen GO:0006621 12 7 0,000 7,982E-03 0,03356305 ! intermediate filament organization GO:0045109 11 7 0,000 7,982E-03 0,03350181 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 7,982E-03 0,03344078 ! cardiac muscle cell development GO:0055013 9 7 0,000 7,982E-03 0,03337998 ! fibrinolysis GO:0042730 9 7 0,000 7,982E-03 0,0333194 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 7,982E-03 0,03325904 ! regulation of circadian rhythm GO:0042752 11 7 0,000 7,982E-03 0,0331989 ! B cell lineage commitment GO:0002326 17 7 0,000 7,982E-03 0,03313897 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 7,982E-03 0,03307926 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 7,982E-03 0,03301977 ! response to tropane GO:0014073 13 7 0,000 7,982E-03 0,03296048 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 7,982E-03 0,03290142 ! melanosome localization GO:0032400 10 7 0,000 7,982E-03 0,03284256 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 7,982E-03 0,03278391 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 7,982E-03 0,03272547 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 7,982E-03 0,03266724 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 7,982E-03 0,03260922 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 7,982E-03 0,0325514 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 7,982E-03 0,03249379 ! multicellular organismal aging GO:0010259 11 7 0,000 7,982E-03 0,03243638 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 7,982E-03 0,03237917 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 7,982E-03 0,03232217 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 7,982E-03 0,03226536 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 7,982E-03 0,03220875 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 7,982E-03 0,03215235 ! establishment of nucleus localization GO:0040023 13 7 0,000 7,982E-03 0,03209614 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 7,982E-03 0,03204012 ! T cell lineage commitment GO:0002360 12 7 0,000 7,982E-03 0,0319843 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 7,982E-03 0,03192868 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 7,982E-03 0,03187325 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 7,982E-03 0,03181801 ! regulation of lipid transport GO:0032368 13 7 0,000 7,982E-03 0,03176296 ! response to tumor cell GO:0002347 12 7 0,000 7,982E-03 0,0317081 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 7,982E-03 0,03165343 ! neuroblast proliferation GO:0007405 13 7 0,000 7,982E-03 0,03159895 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 7,982E-03 0,03154466 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 7,982E-03 0,03149055 ! peptidyl-threonine modification GO:0018210 18 7 0,000 7,982E-03 0,03143663 ! diuresis GO:0030146 12 7 0,000 7,982E-03 0,03138289 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 7,982E-03 0,03132933 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 7,982E-03 0,03127596 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 7,982E-03 0,03122277 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 7,982E-03 0,03116976 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 7,982E-03 0,03111693 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 7,982E-03 0,03106428 ! melanin biosynthetic process GO:0042438 8 7 0,000 7,982E-03 0,03101181 ! regulation of synaptogenesis GO:0051963 10 7 0,000 7,982E-03 0,03095951 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 7,982E-03 0,03090739 ! dopamine biosynthetic process GO:0042416 15 7 0,000 7,982E-03 0,03085545 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 7,982E-03 0,03080367 ! lymph node development GO:0048535 9 7 0,000 7,982E-03 0,03075208 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 7,982E-03 0,03070065 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 7,982E-03 0,0306494 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 7,982E-03 0,03059832 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 7,982E-03 0,0305474 ! endosome to lysosome transport GO:0008333 10 7 0,000 7,982E-03 0,03049666 ! ATP catabolic process GO:0006200 10 7 0,000 7,982E-03 0,03044609 ! establishment of pigment granule localization GO:0051905 13 7 0,000 7,982E-03 0,03039568 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 7,982E-03 0,03034544 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 7,982E-03 0,03029536 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 7,982E-03 0,03024545 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 7,982E-03 0,03019571 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 7,982E-03 0,03014612 ! muscle adaptation GO:0043500 12 7 0,000 7,982E-03 0,0300967 ! amino sugar catabolic process GO:0046348 9 7 0,000 7,982E-03 0,03004745 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 7,982E-03 0,02999835 ! retina homeostasis GO:0001895 9 7 0,000 7,982E-03 0,02994941 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 7,982E-03 0,02990063 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 7,982E-03 0,02985202 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 7,982E-03 0,02980355 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 7,982E-03 0,02975525 ! behavioral response to nicotine GO:0035095 11 7 0,000 7,982E-03 0,0297071 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 7,982E-03 0,02965911 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 7,982E-03 0,02961127 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 9,118E-03 0,03376862 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 9,118E-03 0,03371432 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 9,118E-03 0,03366021 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 9,118E-03 0,03360627 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 9,118E-03 0,0335525 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 9,118E-03 0,0334989 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 9,118E-03 0,03344547 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 9,118E-03 0,03339221 ! cell proliferation in forebrain GO:0021846 10 8 0,000 9,118E-03 0,03333913 ! phosphate transport GO:0006817 10 8 0,000 9,118E-03 0,03328621 ! N-glycan processing GO:0006491 12 8 0,000 9,118E-03 0,03323345 ! Golgi to endosome transport GO:0006895 16 8 0,000 9,118E-03 0,03318087 ! UTP metabolic process GO:0046051 8 8 0,000 9,118E-03 0,03312845 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 9,118E-03 0,0330762 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 9,118E-03 0,03302411 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 9,118E-03 0,03297219 ! neurotransmitter uptake GO:0001504 10 8 0,000 9,118E-03 0,03292042 ! succinate metabolic process GO:0006105 14 8 0,000 9,118E-03 0,03286882 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 9,118E-03 0,03281739 ! smoothened signaling pathway GO:0007224 8 8 0,000 9,118E-03 0,03276611 ! membrane hyperpolarization GO:0060081 10 8 0,000 9,118E-03 0,03271499 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 9,118E-03 0,03266403 ! keratinocyte proliferation GO:0043616 12 8 0,000 9,118E-03 0,03261323 ! middle ear morphogenesis GO:0042474 9 8 0,000 9,118E-03 0,03256259 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 9,118E-03 0,03251211 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 9,118E-03 0,03246178 ! ganglioside metabolic process GO:0001573 15 8 0,000 9,118E-03 0,03241161 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 9,118E-03 0,03236159 ! pseudouridine synthesis GO:0001522 9 8 0,000 9,118E-03 0,03231173 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 9,118E-03 0,03226202 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 9,118E-03 0,03221246 ! endothelial cell differentiation GO:0045446 14 8 0,000 9,118E-03 0,03216305 ! ceramide biosynthetic process GO:0046513 9 8 0,000 9,118E-03 0,0321138 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 9,118E-03 0,03206469 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 9,118E-03 0,03201574 ! astrocyte differentiation GO:0048708 16 8 0,000 9,118E-03 0,03196694 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 9,118E-03 0,03191828 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 9,118E-03 0,03186977 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 9,118E-03 0,03182141 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 9,118E-03 0,0317732 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 9,118E-03 0,03172513 ! melanin metabolic process GO:0006582 12 8 0,000 9,118E-03 0,03167721 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 9,118E-03 0,03162943 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 9,118E-03 0,03158179 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 9,118E-03 0,0315343 ! macrophage activation GO:0042116 12 8 0,000 9,118E-03 0,03148695 ! regulation of type I interferon production GO:0032479 8 8 0,000 9,118E-03 0,03143975 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 9,118E-03 0,03139268 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 9,118E-03 0,03134575 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 9,118E-03 0,03129897 ! regulation of vascular permeability GO:0043114 12 8 0,000 9,118E-03 0,03125232 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 9,118E-03 0,03120582 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 9,118E-03 0,03115945 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 9,118E-03 0,03111322 ! ruffle organization GO:0031529 11 8 0,000 9,118E-03 0,03106713 ! osteoblast development GO:0002076 13 8 0,000 9,118E-03 0,03102117 ! lens development in camera-type eye GO:0002088 10 8 0,000 9,118E-03 0,03097535 ! positive regulation of vasodilation GO:0045909 12 8 0,000 9,118E-03 0,03092966 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 9,118E-03 0,03088411 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 9,118E-03 0,03083869 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 9,118E-03 0,03079341 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 9,118E-03 0,03074826 ! Schwann cell differentiation GO:0014037 17 8 0,000 9,118E-03 0,03070324 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 9,118E-03 0,03065835 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 9,118E-03 0,03061359 ! regulation of gliogenesis GO:0014013 20 8 0,000 9,118E-03 0,03056897 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 9,118E-03 0,03052447 ! oligodendrocyte development GO:0014003 8 8 0,000 9,118E-03 0,0304801 ! segment specification GO:0007379 10 8 0,000 9,118E-03 0,03043586 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 9,118E-03 0,03039175 ! cellular extravasation GO:0045123 11 8 0,000 9,118E-03 0,03034777 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 9,118E-03 0,03030392 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 9,118E-03 0,03026019 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 9,118E-03 0,03021659 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 9,118E-03 0,03017311 ! snRNA metabolic process GO:0016073 10 8 0,000 9,118E-03 0,03012976 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 9,118E-03 0,03008653 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 9,118E-03 0,03004342 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 9,118E-03 0,03000044 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 9,118E-03 0,02995759 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 9,118E-03 0,02991485 ! nucleosome disassembly GO:0006337 12 8 0,000 9,118E-03 0,02987224 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 9,118E-03 0,02982974 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 9,118E-03 0,02978737 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 9,118E-03 0,02974512 ! icosanoid secretion GO:0032309 12 8 0,000 9,118E-03 0,02970299 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 9,118E-03 0,02966098 ! leukocyte activation during immune response GO:0002366 13 8 0,000 9,118E-03 0,02961908 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 9,118E-03 0,02957731 ! cerebellum morphogenesis GO:0021587 9 8 0,000 9,118E-03 0,02953565 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 9,118E-03 0,02949411 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 9,118E-03 0,02945268 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 9,118E-03 0,02941137 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 9,118E-03 0,02937018 ! sterol catabolic process GO:0016127 9 8 0,000 9,118E-03 0,0293291 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 9,118E-03 0,02928814 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 9,118E-03 0,02924729 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 9,118E-03 0,02920656 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 9,118E-03 0,02916594 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 9,118E-03 0,02912543 ! prophase GO:0051324 11 8 0,000 9,118E-03 0,02908503 ! S phase GO:0051320 8 8 0,000 9,118E-03 0,02904475 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 9,118E-03 0,02900458 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 9,118E-03 0,02896452 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 9,118E-03 0,02892457 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 9,118E-03 0,02888472 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 9,118E-03 0,02884499 ! hormone catabolic process GO:0042447 13 8 0,000 9,118E-03 0,02880537 ! quaternary ammonium group transport GO:0015697 10 8 0,000 9,118E-03 0,02876586 ! myeloid cell homeostasis GO:0002262 8 8 0,000 9,118E-03 0,02872645 ! regulation of fibrinolysis GO:0051917 13 8 0,000 9,118E-03 0,02868715 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 9,118E-03 0,02864796 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 9,118E-03 0,02860888 ! regulation of telomere maintenance GO:0032204 10 8 0,000 9,118E-03 0,0285699 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 9,118E-03 0,02853103 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 9,118E-03 0,02849227 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 9,118E-03 0,02845361 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 9,118E-03 0,02841505 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 9,118E-03 0,0283766 ! lamellipodium assembly GO:0030032 9 8 0,000 9,118E-03 0,02833826 ! regulation of embryonic development GO:0045995 16 8 0,000 9,118E-03 0,02830001 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 9,118E-03 0,02826187 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 9,118E-03 0,02822384 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 9,118E-03 0,0281859 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01025165 0,03164938 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01025165 0,03160696 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01025165 0,03156465 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01025165 0,03152245 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01025165 0,03148036 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01025165 0,03143839 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01025165 0,03139653 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01025165 0,03135478 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01025165 0,03131314 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01025165 0,03127161 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01025165 0,03123019 ! GTP metabolic process GO:0046039 9 9 0,000 0,01025165 0,03118888 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01025165 0,03114768 ! social behavior GO:0035176 14 9 0,000 0,01025165 0,03110658 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01025165 0,0310656 ! artery development GO:0060840 19 9 0,000 0,01025165 0,03102472 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01025165 0,03098396 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01025165 0,0309433 ! response to pain GO:0048265 16 9 0,000 0,01025165 0,03090274 ! protein complex disassembly GO:0043241 17 9 0,000 0,01025165 0,03086229 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01025165 0,03082195 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01025165 0,03078171 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01025165 0,03074158 ! lung alveolus development GO:0048286 17 9 0,000 0,01025165 0,03070155 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01025165 0,03066163 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01025165 0,03062181 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01025165 0,03058209 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01025165 0,03054248 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01025165 0,03050296 ! protein targeting to ER GO:0045047 19 9 0,000 0,01025165 0,03046355 ! T cell selection GO:0045058 18 9 0,000 0,01025165 0,03042425 ! endoderm development GO:0007492 12 9 0,000 0,01025165 0,03038504 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01025165 0,03034593 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01025165 0,03030693 ! arginine catabolic process GO:0006527 10 9 0,000 0,01025165 0,03026802 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01025165 0,03022922 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01025165 0,03019051 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01025165 0,03015191 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01025165 0,0301134 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01025165 0,03007499 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01025165 0,03003668 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01025165 0,02999846 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01025165 0,02996034 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01025165 0,02992232 ! mannose metabolic process GO:0006013 9 9 0,000 0,01025165 0,0298844 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01025165 0,02984657 ! receptor clustering GO:0043113 15 9 0,000 0,01025165 0,02980884 ! epithelial cell development GO:0002064 10 9 0,000 0,01025165 0,0297712 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01025165 0,02973366 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01025165 0,02969621 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01025165 0,02965886 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01025165 0,0296216 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01025165 0,02958443 ! motor axon guidance GO:0008045 14 9 0,000 0,01025165 0,02954736 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01025165 0,02951038 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01025165 0,02947349 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01025165 0,02943669 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01025165 0,02939999 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01025165 0,02936338 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01025165 0,02932685 ! DNA ligation GO:0006266 14 9 0,000 0,01025165 0,02929042 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01025165 0,02925408 ! response to amine stimulus GO:0014075 13 9 0,000 0,01025165 0,02921783 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01025165 0,02918167 ! erythrocyte development GO:0048821 11 9 0,000 0,01025165 0,0291456 ! renal water homeostasis GO:0003091 14 9 0,000 0,01025165 0,02910962 ! postreplication repair GO:0006301 11 9 0,000 0,01025165 0,02907372 ! mRNA cleavage GO:0006379 13 9 0,000 0,01025165 0,02903792 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01025165 0,0290022 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01025165 0,02896657 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01025165 0,02893103 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01025165 0,02889558 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01025165 0,02886021 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01025165 0,02882493 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01025165 0,02878973 ! acid secretion GO:0046717 14 9 0,000 0,01025165 0,02875462 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01025165 0,0287196 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01025165 0,02868466 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01025165 0,02864981 ! purine base metabolic process GO:0006144 18 9 0,000 0,01025165 0,02861504 ! oocyte differentiation GO:0009994 12 9 0,000 0,01025165 0,02858035 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01025165 0,02854575 ! spleen development GO:0048536 15 9 0,000 0,01025165 0,02851123 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01025165 0,0284768 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01025165 0,02844245 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01025165 0,02840818 ! detection of calcium ion GO:0005513 13 9 0,000 0,01025165 0,028374 ! blastocyst formation GO:0001825 12 9 0,000 0,01025165 0,02833989 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01025165 0,02830587 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01025165 0,02827193 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01025165 0,02823807 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01025165 0,0282043 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01025165 0,0281706 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01025165 0,02813698 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01025165 0,02810345 ! prepulse inhibition GO:0060134 14 9 0,000 0,01025165 0,02806999 ! embryonic placenta development GO:0001892 12 9 0,000 0,01025165 0,02803661 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01025165 0,02800331 ! insulin secretion GO:0030073 17 9 0,000 0,01025165 0,0279701 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01025165 0,02793696 ! response to nicotine GO:0035094 16 9 0,000 0,01025165 0,02790389 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01025165 0,02787091 ! nucleus localization GO:0051647 15 9 0,000 0,01025165 0,02783801 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01025165 0,02780518 ! localization within membrane GO:0051668 15 9 0,000 0,01025165 0,02777243 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01138454 0,03080522 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01138454 0,03076902 ! neuron fate specification GO:0048665 11 10 0,000 0,01138454 0,03073291 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01138454 0,03069688 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01138454 0,03066093 ! thyroid gland development GO:0030878 19 10 0,000 0,01138454 0,03062507 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01138454 0,03058929 ! synapsis GO:0007129 13 10 0,000 0,01138454 0,0305536 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01138454 0,03051799 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01138454 0,03048246 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01138454 0,03044702 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01138454 0,03041166 ! sulfate transport GO:0008272 12 10 0,000 0,01138454 0,03037637 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01138454 0,03034118 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01138454 0,03030606 ! androgen metabolic process GO:0008209 13 10 0,000 0,01138454 0,03027102 ! phospholipid efflux GO:0033700 16 10 0,000 0,01138454 0,03023607 ! hippocampus development GO:0021766 19 10 0,000 0,01138454 0,03020119 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01138454 0,0301664 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01138454 0,03013169 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01138454 0,03009705 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01138454 0,0300625 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01138454 0,03002802 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01138454 0,02999363 ! pathogenesis GO:0009405 13 10 0,000 0,01138454 0,02995931 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01138454 0,02992507 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01138454 0,02989091 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01138454 0,02985682 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01138454 0,02982282 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01138454 0,02978889 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01138454 0,02975504 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01138454 0,02972127 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01138454 0,02968757 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01138454 0,02965395 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01138454 0,0296204 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01138454 0,02958693 ! response to X-ray GO:0010165 16 10 0,000 0,01138454 0,02955354 ! B cell proliferation GO:0042100 14 10 0,000 0,01138454 0,02952022 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01138454 0,02948698 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01138454 0,02945381 ! forebrain cell migration GO:0021885 17 10 0,000 0,01138454 0,02942071 ! lipid digestion GO:0044241 15 10 0,000 0,01138454 0,02938769 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01138454 0,02935475 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01138454 0,02932188 ! UV protection GO:0009650 14 10 0,000 0,01138454 0,02928908 ! entry into host cell GO:0030260 20 10 0,000 0,01138454 0,02925635 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01138454 0,0292237 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01138454 0,02919112 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01138454 0,02915861 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01138454 0,02912618 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01138454 0,02909382 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01138454 0,02906153 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01138454 0,02902931 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01138454 0,02899716 ! regulation of organ growth GO:0046620 11 10 0,000 0,01138454 0,02896508 ! response to dsRNA GO:0043331 18 10 0,000 0,01138454 0,02893308 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01138454 0,02890114 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01138454 0,02886928 ! embryonic axis specification GO:0000578 12 10 0,000 0,01138454 0,02883748 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01138454 0,02880576 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01138454 0,0287741 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01138454 0,02874252 ! cranial nerve development GO:0021545 12 10 0,000 0,01138454 0,028711 ! fucose catabolic process GO:0019317 16 10 0,000 0,01138454 0,02867956 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01138454 0,02864818 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01138454 0,02861687 ! protein sumoylation GO:0016925 12 10 0,000 0,01138454 0,02858563 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01138454 0,02855445 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01138454 0,02852335 ! zymogen activation GO:0031638 14 10 0,000 0,01138454 0,02849231 ! salivary gland development GO:0007431 22 10 0,000 0,01138454 0,02846134 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01138454 0,02843044 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01138454 0,0283996 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01138454 0,02836884 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01138454 0,02833813 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01138454 0,0283075 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01138454 0,02827693 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01138454 0,02824642 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01138454 0,02821599 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01138454 0,02818561 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01138454 0,02815531 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01138454 0,02812506 ! detection of bacterium GO:0016045 10 10 0,000 0,01138454 0,02809489 ! embryonic gut development GO:0048566 11 10 0,000 0,01138454 0,02806478 ! activation of innate immune response GO:0002218 10 10 0,000 0,01138454 0,02803473 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01138454 0,02800474 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01138454 0,02797482 ! developmental induction GO:0031128 13 10 0,000 0,01138454 0,02794497 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01138454 0,02791518 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01138454 0,02788545 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01138454 0,02785578 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01138454 0,02782618 ! rRNA transcription GO:0009303 17 11 0,000 0,01251619 0,03055971 ! respiratory burst GO:0045730 14 11 0,000 0,01251619 0,0305273 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01251619 0,03049496 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01251619 0,03046269 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01251619 0,03043049 ! virus-host interaction GO:0019048 17 11 0,000 0,01251619 0,03039836 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01251619 0,03036629 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01251619 0,0303343 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01251619 0,03030236 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01251619 0,0302705 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01251619 0,0302387 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01251619 0,03020697 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01251619 0,03017531 ! mating GO:0007618 14 11 0,000 0,01251619 0,03014371 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01251619 0,03011218 ! T cell proliferation GO:0042098 20 11 0,000 0,01251619 0,03008072 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01251619 0,03004932 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01251619 0,03001798 ! bone resorption GO:0045453 16 11 0,000 0,01251619 0,02998671 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01251619 0,02995551 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01251619 0,02992437 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01251619 0,0298933 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01251619 0,02986229 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01251619 0,02983134 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01251619 0,02980046 ! syncytium formation GO:0006949 15 11 0,000 0,01251619 0,02976964 ! plasma membrane organization GO:0007009 18 11 0,000 0,01251619 0,02973889 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01251619 0,0297082 ! focal adhesion formation GO:0048041 24 11 0,000 0,01251619 0,02967757 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01251619 0,02964701 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01251619 0,02961651 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01251619 0,02958607 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01251619 0,02955569 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01251619 0,02952538 ! adult heart development GO:0007512 11 11 0,000 0,01251619 0,02949513 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01251619 0,02946494 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01251619 0,02943481 ! temperature homeostasis GO:0001659 16 11 0,000 0,01251619 0,02940475 ! L-glutamate transport GO:0015813 16 11 0,000 0,01251619 0,02937474 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01251619 0,0293448 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01251619 0,02931491 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01251619 0,02928509 ! stem cell development GO:0048864 29 11 0,000 0,01251619 0,02925533 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01251619 0,02922563 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01251619 0,02919599 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01251619 0,02916641 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01251619 0,02913689 ! vasoconstriction GO:0042310 15 11 0,000 0,01251619 0,02910743 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01251619 0,02907803 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01251619 0,02904868 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01251619 0,0290194 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01251619 0,02899018 ! ribosome assembly GO:0042255 13 11 0,000 0,01251619 0,02896101 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01251619 0,02893191 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01251619 0,02890286 ! chromatin silencing GO:0006342 19 11 0,000 0,01251619 0,02887387 ! nucleosome positioning GO:0016584 13 11 0,000 0,01251619 0,02884494 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01251619 0,02881606 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01251619 0,02878725 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01251619 0,02875849 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01251619 0,02872979 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01251619 0,02870114 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01251619 0,02867256 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01251619 0,02864403 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01251619 0,02861555 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01251619 0,02858714 ! male genitalia development GO:0030539 13 11 0,000 0,01251619 0,02855878 ! cholesterol efflux GO:0033344 19 11 0,000 0,01251619 0,02853047 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01251619 0,02850222 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01251619 0,02847403 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01251619 0,0284459 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01251619 0,02841781 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01251619 0,02838979 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01251619 0,02836182 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01251619 0,0283339 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01251619 0,02830604 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01251619 0,02827824 ! lysogeny GO:0030069 18 11 0,000 0,01251619 0,02825049 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01251619 0,02822279 ! acrosome reaction GO:0007340 13 11 0,000 0,01251619 0,02819515 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01251619 0,02816756 ! lactation GO:0007595 20 12 0,000 0,01364662 0,03068155 ! reproductive cellular process GO:0048610 14 12 0,000 0,01364662 0,03065159 ! tRNA modification GO:0006400 14 12 0,000 0,01364662 0,03062168 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01364662 0,03059184 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01364662 0,03056205 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01364662 0,03053232 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01364662 0,03050265 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01364662 0,03047304 ! non-recombinational repair GO:0000726 19 12 0,000 0,01364662 0,03044348 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01364662 0,03041398 ! peroxisomal transport GO:0043574 21 12 0,000 0,01364662 0,03038454 ! cartilage condensation GO:0001502 18 12 0,000 0,01364662 0,03035515 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01364662 0,03032582 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01364662 0,03029655 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01364662 0,03026733 ! heart looping GO:0001947 15 12 0,000 0,01364662 0,03023818 ! palate development GO:0060021 15 12 0,000 0,01364662 0,03020907 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01364662 0,03018003 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01364662 0,03015103 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01364662 0,0301221 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01364662 0,03009322 ! arginine metabolic process GO:0006525 13 12 0,000 0,01364662 0,03006439 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01364662 0,03003562 ! methionine metabolic process GO:0006555 13 12 0,000 0,01364662 0,03000691 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01364662 0,02997825 ! Golgi organization GO:0007030 18 12 0,000 0,01364662 0,02994964 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01364662 0,02992109 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01364662 0,0298926 ! monoamine transport GO:0015844 13 12 0,000 0,01364662 0,02986415 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01364662 0,02983577 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01364662 0,02980743 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01364662 0,02977915 ! L-amino acid transport GO:0015807 20 12 0,000 0,01364662 0,02975093 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01364662 0,02972275 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01364662 0,02969463 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01364662 0,02966657 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01364662 0,02963855 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01364662 0,02961059 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01364662 0,02958268 ! cerebellum development GO:0021549 13 12 0,000 0,01364662 0,02955483 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01364662 0,02952702 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01364662 0,02949927 ! histone acetylation GO:0016573 23 12 0,000 0,01364662 0,02947157 ! histone methylation GO:0016571 15 12 0,000 0,01364662 0,02944393 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01364662 0,02941633 ! gland morphogenesis GO:0022612 23 12 0,000 0,01364662 0,02938879 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01364662 0,0293613 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01364662 0,02933386 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01364662 0,02930647 ! response to gamma radiation GO:0010332 20 12 0,000 0,01364662 0,02927913 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01364662 0,02925184 ! intestinal absorption GO:0050892 19 12 0,000 0,01364662 0,02922461 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01364662 0,02919742 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01364662 0,02917028 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01364662 0,0291432 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01364662 0,02911617 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01364662 0,02908918 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01364662 0,02906225 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01364662 0,02903536 ! microspike assembly GO:0030035 23 12 0,000 0,01364662 0,02900853 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01364662 0,02898174 ! response to cold GO:0009409 14 12 0,000 0,01364662 0,02895501 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01477582 0,03132201 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01477582 0,03129317 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01477582 0,03126438 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01477582 0,03123564 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01477582 0,03120696 ! water transport GO:0006833 17 13 0,000 0,01477582 0,03117833 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01477582 0,03114975 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01477582 0,03112123 ! lipid localization GO:0010876 24 13 0,000 0,01477582 0,03109275 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01477582 0,03106433 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01477582 0,03103596 ! organelle fusion GO:0048284 28 13 0,000 0,01477582 0,03100764 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01477582 0,03097938 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01477582 0,03095116 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01477582 0,030923 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01477582 0,03089489 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01477582 0,03086683 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01477582 0,03083882 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01477582 0,03081086 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01477582 0,03078295 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01477582 0,03075509 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01477582 0,03072729 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01477582 0,03069953 ! NAD metabolic process GO:0019674 21 13 0,000 0,01477582 0,03067182 ! exocrine system development GO:0035272 27 13 0,000 0,01477582 0,03064416 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01477582 0,03061656 ! bone mineralization GO:0030282 15 13 0,000 0,01477582 0,030589 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01477582 0,03056149 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01477582 0,03053403 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01477582 0,03050662 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01477582 0,03047926 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01477582 0,03045195 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01477582 0,03042469 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01477582 0,03039748 ! genitalia development GO:0048806 15 13 0,000 0,01477582 0,03037031 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01477582 0,0303432 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01477582 0,03031613 ! cellular pigmentation GO:0033059 24 13 0,000 0,01477582 0,03028911 ! tissue regeneration GO:0042246 21 13 0,000 0,01477582 0,03026214 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01477582 0,03023521 ! cofactor transport GO:0051181 19 13 0,000 0,01477582 0,03020834 ! NADP metabolic process GO:0006739 18 13 0,000 0,01477582 0,03018151 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01477582 0,03015473 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01477582 0,030128 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01477582 0,03010131 ! gas transport GO:0015669 18 13 0,000 0,01477582 0,03007467 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01477582 0,03004808 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01477582 0,03002154 ! regulation of axon extension GO:0030516 23 13 0,000 0,01477582 0,02999504 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01477582 0,02996859 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01477582 0,02994218 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01477582 0,02991583 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01477582 0,02988952 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01477582 0,02986325 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,01590379 0,03211476 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,01590379 0,03208658 ! superoxide anion generation GO:0042554 18 14 0,000 0,01590379 0,03205846 ! neuron maturation GO:0042551 21 14 0,000 0,01590379 0,03203039 ! regulation of S phase GO:0033261 18 14 0,000 0,01590379 0,03200237 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,01590379 0,03197439 ! myotube differentiation GO:0014902 21 14 0,000 0,01590379 0,03194647 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01590379 0,03191859 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,01590379 0,03189076 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01590379 0,03186298 ! inositol metabolic process GO:0006020 20 14 0,000 0,01590379 0,03183525 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01590379 0,03180757 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01590379 0,03177994 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01590379 0,03175235 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01590379 0,03172481 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01590379 0,03169732 ! response to cAMP GO:0051591 19 14 0,000 0,01590379 0,03166988 ! limbic system development GO:0021761 25 14 0,000 0,01590379 0,03164248 ! startle response GO:0001964 21 14 0,000 0,01590379 0,03161513 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01590379 0,03158783 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01590379 0,03156058 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01590379 0,03153337 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01590379 0,03150621 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,01590379 0,03147909 ! glycine metabolic process GO:0006544 22 14 0,000 0,01590379 0,03145203 ! pituitary gland development GO:0021983 23 14 0,000 0,01590379 0,03142501 ! cellular response to starvation GO:0009267 21 14 0,000 0,01590379 0,03139803 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01590379 0,0313711 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01590379 0,03134422 ! regulation of heart rate GO:0002027 23 14 0,000 0,01590379 0,03131739 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01590379 0,0312906 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,01590379 0,03126385 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01590379 0,03123715 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01590379 0,0312105 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01590379 0,03118389 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01590379 0,03115733 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01590379 0,03113081 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01590379 0,03110434 ! axon cargo transport GO:0008088 27 14 0,000 0,01590379 0,03107792 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01590379 0,03105153 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01590379 0,0310252 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01590379 0,0309989 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01590379 0,03097266 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01590379 0,03094645 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01590379 0,03092029 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01590379 0,03089418 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01590379 0,03086811 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01590379 0,03084208 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01590379 0,0308161 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01590379 0,03079016 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01590379 0,03076426 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01590379 0,03073841 ! muscle maintenance GO:0046716 19 14 0,000 0,01590379 0,0307126 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01590379 0,03068683 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01590379 0,03066111 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01590379 0,03063543 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01590379 0,0306098 ! cell killing GO:0001906 20 14 0,000 0,01590379 0,0305842 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,01590379 0,03055865 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,01590379 0,03053314 ! cilium assembly GO:0042384 20 14 0,000 0,01590379 0,03050768 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01590379 0,03048226 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,01703053 0,03261466 ! positive regulation of cell size GO:0045793 20 15 0,000 0,01703053 0,03258753 ! metencephalon development GO:0022037 19 15 0,000 0,01703053 0,03256044 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01703053 0,0325334 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01703053 0,0325064 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01703053 0,03247945 ! skin development GO:0043588 25 15 0,000 0,01703053 0,03245254 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,01703053 0,03242567 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01703053 0,03239885 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01703053 0,03237208 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,01703053 0,03234534 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01703053 0,03231866 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01703053 0,03229201 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01703053 0,03226541 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01703053 0,03223886 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,01703053 0,03221235 ! adult walking behavior GO:0007628 25 15 0,000 0,01703053 0,03218588 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01703053 0,03215945 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01703053 0,03213307 ! myoblast differentiation GO:0045445 27 15 0,000 0,01703053 0,03210673 ! centrosome cycle GO:0007098 16 15 0,000 0,01703053 0,03208044 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01703053 0,03205418 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01703053 0,03202797 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01703053 0,03200181 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01703053 0,03197568 ! cerebral cortex development GO:0021987 29 15 0,000 0,01703053 0,0319496 ! response to osmotic stress GO:0006970 22 15 0,000 0,01703053 0,03192356 ! vesicle coating GO:0006901 25 15 0,000 0,01703053 0,03189757 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01703053 0,03187161 ! DNA integration GO:0015074 22 15 0,000 0,01703053 0,0318457 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,01703053 0,03181983 ! peptide secretion GO:0002790 27 15 0,000 0,01703053 0,031794 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01703053 0,03176822 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01703053 0,03174247 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01703053 0,03171677 ! neuron recognition GO:0008038 22 15 0,000 0,01703053 0,03169111 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01703053 0,03166549 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01703053 0,03163991 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,01703053 0,03161438 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,01703053 0,03158888 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01703053 0,03156343 ! biomineral formation GO:0031214 18 15 0,000 0,01703053 0,03153801 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01703053 0,03151264 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01703053 0,03148731 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01703053 0,03146202 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01703053 0,03143677 ! organic cation transport GO:0015695 19 15 0,000 0,01703053 0,03141156 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01703053 0,03138639 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01703053 0,03136126 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01703053 0,03133617 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01703053 0,03131112 ! defense response to virus GO:0051607 27 15 0,000 0,01703053 0,03128611 ! peptide hormone processing GO:0016486 19 15 0,000 0,01703053 0,03126114 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01703053 0,03123621 ! protein secretion GO:0009306 27 16 0,000 0,01815604 0,03327402 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,01815604 0,03324753 ! hormone secretion GO:0046879 25 16 0,000 0,01815604 0,03322108 ! bone remodeling GO:0046849 24 16 0,000 0,01815604 0,03319467 ! endothelial cell migration GO:0043542 22 16 0,000 0,01815604 0,03316831 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,01815604 0,03314198 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01815604 0,0331157 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01815604 0,03308946 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01815604 0,03306326 ! glial cell development GO:0021782 24 16 0,000 0,01815604 0,0330371 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01815604 0,03301099 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01815604 0,03298491 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01815604 0,03295888 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01815604 0,03293289 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01815604 0,03290693 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01815604 0,03288102 ! fructose metabolic process GO:0006000 20 16 0,000 0,01815604 0,03285515 ! regulation of protein binding GO:0043393 27 16 0,000 0,01815604 0,03282932 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,01815604 0,03280353 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01815604 0,03277779 ! protein export from nucleus GO:0006611 24 16 0,000 0,01815604 0,03275208 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01815604 0,03272641 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,01815604 0,03270078 ! DNA replication initiation GO:0006270 25 16 0,000 0,01815604 0,0326752 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01815604 0,03264965 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01815604 0,03262414 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01815604 0,03259867 ! diencephalon development GO:0021536 25 16 0,000 0,01815604 0,03257324 ! oogenesis GO:0048477 23 16 0,000 0,01815604 0,03254786 ! neural crest cell migration GO:0001755 24 16 0,000 0,01815604 0,03252251 ! G1 phase GO:0051318 27 16 0,000 0,01815604 0,0324972 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01815604 0,03247193 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01815604 0,0324467 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01815604 0,03242151 ! steroid catabolic process GO:0006706 22 16 0,000 0,01815604 0,03239635 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01815604 0,03237124 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01815604 0,03234617 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,01815604 0,03232113 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01815604 0,03229613 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01815604 0,03227117 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01815604 0,03224625 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01815604 0,03222137 ! nerve development GO:0021675 18 16 0,000 0,01815604 0,03219653 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01815604 0,03217173 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01815604 0,03214696 ! negative regulation of translation GO:0017148 22 16 0,000 0,01815604 0,03212223 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,01928034 0,03408514 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,01928034 0,03405896 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01928034 0,03403282 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,01928034 0,03400673 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,01928034 0,03398067 ! glycerol metabolic process GO:0006071 20 17 0,000 0,01928034 0,03395465 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,01928034 0,03392867 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,01928034 0,03390273 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01928034 0,03387683 ! signal complex assembly GO:0007172 29 17 0,000 0,01928034 0,03385097 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,01928034 0,03382515 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,01928034 0,03379937 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,01928034 0,03377363 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,01928034 0,03374792 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,01928034 0,03372226 ! memory GO:0007613 25 17 0,000 0,01928034 0,03369663 ! keratinization GO:0031424 17 17 0,000 0,01928034 0,03367105 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,01928034 0,0336455 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,01928034 0,03361999 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01928034 0,03359452 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,01928034 0,03356909 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,01928034 0,0335437 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,01928034 0,03351835 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,01928034 0,03349303 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,01928034 0,03346775 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,01928034 0,03344251 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,01928034 0,03341731 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,01928034 0,03339215 ! membrane budding GO:0006900 29 17 0,000 0,01928034 0,03336702 ! heme metabolic process GO:0042168 27 17 0,000 0,01928034 0,03334193 ! actin filament bundle formation GO:0051017 26 17 0,000 0,01928034 0,03331688 ! neuromuscular junction development GO:0007528 23 17 0,000 0,01928034 0,03329187 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,01928034 0,03326689 ! body fluid secretion GO:0007589 27 17 0,000 0,01928034 0,03324196 ! stem cell differentiation GO:0048863 36 17 0,000 0,01928034 0,03321706 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01928034 0,03319219 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,01928034 0,03316737 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,01928034 0,03314258 ! sensory perception of pain GO:0019233 23 17 0,000 0,01928034 0,03311783 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,01928034 0,03309311 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,01928034 0,03306843 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,01928034 0,03304379 ! synaptogenesis GO:0007416 24 17 0,000 0,01928034 0,03301919 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,01928034 0,03299462 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01928034 0,03297009 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,01928034 0,03294559 ! cell-cell junction organization GO:0045216 25 17 0,000 0,01928034 0,03292114 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,01928034 0,03289671 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,01928034 0,03287233 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,01928034 0,03284798 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,01928034 0,03282366 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,01928034 0,03279939 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,01928034 0,03277514 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,0204034 0,03465866 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,0204034 0,03463308 ! positive regulation of translation GO:0045727 28 18 0,000 0,0204034 0,03460754 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,0204034 0,03458204 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,0204034 0,03455657 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,0204034 0,03453115 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,0204034 0,03450576 ! cAMP metabolic process GO:0046058 33 18 0,000 0,0204034 0,0344804 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,0204034 0,03445509 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,0204034 0,03442981 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,0204034 0,03440457 ! axis specification GO:0009798 26 18 0,000 0,0204034 0,03437936 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,0204034 0,03435419 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,0204034 0,03432906 ! pancreas development GO:0031016 26 18 0,000 0,0204034 0,03430397 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,0204034 0,03427891 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,0204034 0,03425389 ! glutamine metabolic process GO:0006541 23 18 0,000 0,0204034 0,0342289 ! response to retinoic acid GO:0032526 25 18 0,000 0,0204034 0,03420396 ! pigmentation during development GO:0048066 31 18 0,000 0,0204034 0,03417904 ! central nervous system neuron development GO:0021954 30 18 0,000 0,0204034 0,03415417 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,0204034 0,03412933 ! fucose metabolic process GO:0006004 26 18 0,000 0,0204034 0,03410453 ! response to fungus GO:0009620 19 18 0,000 0,0204034 0,03407976 ! peptide cross-linking GO:0018149 31 18 0,000 0,0204034 0,03405503 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,0204034 0,03403033 ! heart process GO:0003015 27 18 0,000 0,0204034 0,03400567 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,0204034 0,03398105 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,0204034 0,03395646 ! visual learning GO:0008542 35 18 0,000 0,0204034 0,03393191 ! somitogenesis GO:0001756 24 18 0,000 0,0204034 0,03390739 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,0204034 0,03388291 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,0204034 0,03385846 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,0204034 0,03383405 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,0204034 0,03380967 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,0204034 0,03378533 ! vitamin transport GO:0051180 24 18 0,000 0,0204034 0,03376103 ! hormone transport GO:0009914 27 18 0,000 0,0204034 0,03373676 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,0204034 0,03371252 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,0204034 0,03368832 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,0204034 0,03366415 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,0204034 0,03364002 ! cell-cell recognition GO:0009988 20 18 0,000 0,0204034 0,03361592 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,0204034 0,03359186 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,0204034 0,03356783 ! regulation of glucose import GO:0046324 21 18 0,000 0,0204034 0,03354384 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,0204034 0,03351988 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,0204034 0,03349595 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,0204034 0,03347206 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,0204034 0,0334482 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,02152525 0,03526216 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,02152525 0,03523706 ! positive regulation of ossification GO:0045778 30 19 0,000 0,02152525 0,035212 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,02152525 0,03518698 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,02152525 0,03516199 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,02152525 0,03513703 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,02152525 0,03511211 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,02152525 0,03508723 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,02152525 0,03506238 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,02152525 0,03503756 ! regeneration GO:0031099 32 19 0,000 0,02152525 0,03501278 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,02152525 0,03498804 ! response to alkaloid GO:0043279 32 19 0,000 0,02152525 0,03496333 ! sensory perception of taste GO:0050909 23 19 0,000 0,02152525 0,03493866 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,02152525 0,03491402 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,02152525 0,03488941 ! smooth muscle contraction GO:0006939 36 19 0,000 0,02152525 0,03486484 ! peroxisome organization GO:0007031 29 19 0,000 0,02152525 0,03484031 ! digestive system process GO:0022600 30 19 0,000 0,02152525 0,03481581 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,02152525 0,03479134 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,02152525 0,03476691 ! response to vitamin A GO:0033189 26 19 0,000 0,02152525 0,03474251 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,02152525 0,03471815 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,02152525 0,03469382 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,02152525 0,03466952 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,02152525 0,03464526 ! response to starvation GO:0042594 30 19 0,000 0,02152525 0,03462103 ! sex determination GO:0007530 29 19 0,000 0,02152525 0,03459684 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,02152525 0,03457268 ! plasma membrane fusion GO:0045026 23 19 0,000 0,02152525 0,03454855 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,02152525 0,03452446 ! cytolysis GO:0019835 20 19 0,000 0,02152525 0,0345004 ! renal system process GO:0003014 35 19 0,000 0,02152525 0,03447638 ! vasodilation GO:0042311 33 19 0,000 0,02152525 0,03445238 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,02152525 0,03442843 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,02152525 0,0344045 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,02152525 0,03438061 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,02152525 0,03435675 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,02152525 0,03433292 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,02152525 0,03430913 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,02152525 0,03428537 ! sarcomere organization GO:0045214 23 19 0,000 0,02152525 0,03426164 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,02152525 0,03423795 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,02152525 0,03421429 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,02152525 0,03419066 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,02152525 0,03416706 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,02152525 0,0341435 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,02152525 0,03411997 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,02152525 0,03409647 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,02152525 0,034073 ! protein stabilization GO:0050821 26 19 0,000 0,02152525 0,03404957 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,02264588 0,03579761 ! iron ion transport GO:0006826 37 20 0,000 0,02264588 0,03577302 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,02264588 0,03574847 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,02264588 0,03572395 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,02264588 0,03569946 ! response to vitamin GO:0033273 29 20 0,000 0,02264588 0,03567501 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,02264588 0,03565059 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,02264588 0,03562621 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,02264588 0,03560186 ! spinal cord development GO:0021510 31 20 0,000 0,02264588 0,03557754 ! response to ethanol GO:0045471 37 20 0,000 0,02264588 0,03555325 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,02264588 0,035529 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,02264588 0,03550478 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,02264588 0,0354806 ! chromosome condensation GO:0030261 31 20 0,000 0,02264588 0,03545644 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,02264588 0,03543232 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,02264588 0,03540824 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,02264588 0,03538418 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,02264588 0,03536016 ! pallium development GO:0021543 38 20 0,000 0,02264588 0,03533617 ! DNA modification GO:0006304 28 20 0,000 0,02264588 0,03531221 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,02264588 0,03528829 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,02264588 0,0352644 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,02264588 0,03524054 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,02264588 0,03521671 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,02264588 0,03519292 ! collagen catabolic process GO:0030574 25 20 0,000 0,02264588 0,03516915 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,02264588 0,03514542 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,02264588 0,03512172 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,02264588 0,03509806 ! alditol metabolic process GO:0019400 24 20 0,000 0,02264588 0,03507442 ! actin filament-based movement GO:0030048 34 20 0,000 0,02264588 0,03505082 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,02376528 0,03675868 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,02376528 0,03673397 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,02376528 0,0367093 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02376528 0,03668467 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02376528 0,03666006 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,02376528 0,03663549 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,02376528 0,03661095 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,02376528 0,03658645 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,02376528 0,03656197 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,02376528 0,03653753 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,02376528 0,03651313 ! protein amino acid acylation GO:0043543 37 21 0,000 0,02376528 0,03648875 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,02376528 0,03646441 ! vesicle docking GO:0048278 27 21 0,000 0,02376528 0,0364401 ! phototransduction GO:0007602 25 21 0,000 0,02376528 0,03641582 ! dendrite development GO:0016358 35 21 0,000 0,02376528 0,03639158 ! visual behavior GO:0007632 39 21 0,000 0,02376528 0,03636737 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,02376528 0,03634319 ! ovarian follicle development GO:0001541 30 21 0,000 0,02376528 0,03631904 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,02376528 0,03629492 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,02376528 0,03627084 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,02376528 0,03624679 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,02376528 0,03622276 ! cell aging GO:0007569 32 21 0,000 0,02376528 0,03619878 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,02376528 0,03617482 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,02376528 0,03615089 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,02376528 0,036127 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,02376528 0,03610314 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,02376528 0,03607931 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,02376528 0,03605551 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,02376528 0,03603174 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,02376528 0,03600801 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,02376528 0,0359843 ! fatty acid transport GO:0015908 30 21 0,000 0,02376528 0,03596063 ! immunoglobulin production GO:0002377 33 21 0,000 0,02376528 0,03593698 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,02376528 0,03591337 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,02376528 0,03588979 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,02376528 0,03586624 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,02376528 0,03584272 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02376528 0,03581923 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,02376528 0,03579578 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,02376528 0,03577235 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02376528 0,03574895 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,02376528 0,03572559 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,02376528 0,03570225 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,02376528 0,03567895 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,02376528 0,03565568 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,02376528 0,03563243 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,02488347 0,03728468 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,02488347 0,03726041 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,02488347 0,03723617 ! viral genome replication GO:0019079 29 22 0,000 0,02488347 0,03721195 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,02488347 0,03718778 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,02488347 0,03716363 ! leukocyte adhesion GO:0007159 38 22 0,000 0,02488347 0,03713951 ! molting cycle process GO:0022404 40 22 0,000 0,02488347 0,03711543 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,02488347 0,03709137 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,02488347 0,03706735 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,02488347 0,03704336 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,02488347 0,0370194 ! vasculogenesis GO:0001570 33 22 0,000 0,02488347 0,03699547 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,02488347 0,03697157 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,02488347 0,0369477 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,02488347 0,03692386 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,02488347 0,03690006 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,02488347 0,03687628 ! lysosome organization GO:0007040 37 22 0,000 0,02488347 0,03685253 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,02488347 0,03682882 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,02488347 0,03680514 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,02488347 0,03678148 ! regulation of behavior GO:0050795 38 22 0,000 0,02488347 0,03675786 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,02488347 0,03673427 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,02488347 0,0367107 ! membrane depolarization GO:0051899 35 22 0,000 0,02488347 0,03668717 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,02488347 0,03666367 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,02488347 0,0366402 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,02488347 0,03661675 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,02488347 0,03659334 ! blastocyst development GO:0001824 37 22 0,000 0,02488347 0,03656996 ! neural tube closure GO:0001843 33 22 0,000 0,02488347 0,03654661 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,02488347 0,03652328 ! protein tetramerization GO:0051262 39 22 0,000 0,02488347 0,03649999 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,02600044 0,0381141 ! neuron fate commitment GO:0048663 32 23 0,000 0,02600044 0,03808982 ! embryonic pattern specification GO:0009880 31 23 0,000 0,02600044 0,03806558 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,02600044 0,03804136 ! myelination GO:0042552 35 23 0,000 0,02600044 0,03801718 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,02600044 0,03799303 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,02600044 0,0379689 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,02600044 0,03794481 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,02600044 0,03792075 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,02600044 0,03789672 ! vesicle targeting GO:0006903 32 23 0,000 0,02600044 0,03787272 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,02600044 0,03784875 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,02600044 0,03782481 ! osteoblast differentiation GO:0001649 40 23 0,000 0,02600044 0,0378009 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,02600044 0,03777702 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,02600044 0,03775317 ! interaction with host GO:0051701 37 23 0,000 0,02600044 0,03772935 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,02600044 0,03770556 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,02600044 0,0376818 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,02600044 0,03765807 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,02600044 0,03763437 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02600044 0,03761071 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,02600044 0,03758707 ! cell fate determination GO:0001709 45 23 0,000 0,02600044 0,03756346 ! pentose metabolic process GO:0019321 31 23 0,000 0,02600044 0,03753988 ! spermatid development GO:0007286 33 23 0,000 0,02600044 0,03751632 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,02600044 0,0374928 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,02600044 0,03746931 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02600044 0,03744585 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,02600044 0,03742242 ! telomere organization GO:0032200 32 23 0,000 0,02600044 0,03739901 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,02600044 0,03737564 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,02600044 0,03735229 ! regulation of amine transport GO:0051952 38 23 0,000 0,02600044 0,03732898 ! liver development GO:0001889 40 23 0,000 0,02600044 0,03730569 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,0271162 0,03888233 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,0271162 0,03885811 ! initiation of viral infection GO:0019059 42 24 0,000 0,0271162 0,03883391 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,0271162 0,03880975 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,0271162 0,03878561 ! superoxide metabolic process GO:0006801 32 24 0,000 0,0271162 0,0387615 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,0271162 0,03873743 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,0271162 0,03871338 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,0271162 0,03868937 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,0271162 0,03866538 ! sperm motility GO:0030317 27 24 0,000 0,0271162 0,03864143 ! vacuole organization GO:0007033 39 24 0,000 0,0271162 0,0386175 ! receptor metabolic process GO:0043112 37 24 0,000 0,0271162 0,0385936 ! neural crest cell development GO:0014032 39 24 0,000 0,0271162 0,03856973 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,0271162 0,0385459 ! primary neural tube formation GO:0014020 35 24 0,000 0,0271162 0,03852209 ! negative regulation of cell development GO:0010721 56 24 0,000 0,0271162 0,03849831 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,0271162 0,03847456 ! base-excision repair GO:0006284 31 24 0,000 0,0271162 0,03845084 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,0271162 0,03842715 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,0271162 0,03840349 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,0271162 0,03837985 ! glutathione metabolic process GO:0006749 29 24 0,000 0,0271162 0,03835625 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,0271162 0,03833267 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,0271162 0,03830913 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,0271162 0,03828561 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,02823074 0,03983479 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,02823074 0,03981037 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,02823074 0,03978597 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,02823074 0,03976161 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,02823074 0,03973728 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,02823074 0,03971297 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,02823074 0,0396887 ! peptide transport GO:0015833 43 25 0,000 0,02823074 0,03966445 ! male gonad development GO:0008584 33 25 0,000 0,02823074 0,03964024 ! iron ion homeostasis GO:0055072 39 25 0,000 0,02823074 0,03961605 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,02823074 0,0395919 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,02823074 0,03956777 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,02823074 0,03954367 ! phospholipid transport GO:0015914 35 25 0,000 0,02823074 0,0395196 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,02823074 0,03949556 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,02823074 0,03947156 ! detection of light stimulus GO:0009583 30 25 0,000 0,02823074 0,03944757 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,02823074 0,03942362 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,02823074 0,0393997 ! leukocyte proliferation GO:0070661 39 25 0,000 0,02823074 0,03937581 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,02823074 0,03935194 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,02934407 0,04087908 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,02934407 0,04085434 ! translational initiation GO:0006413 43 26 0,000 0,02934407 0,04082962 ! regulation of pH GO:0006885 36 26 0,000 0,02934407 0,04080494 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,02934407 0,04078028 ! circadian rhythm GO:0007623 42 26 0,000 0,02934407 0,04075566 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,02934407 0,04073106 ! post-embryonic development GO:0009791 42 26 0,000 0,02934407 0,04070649 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,02934407 0,04068196 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,02934407 0,04065745 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,02934407 0,04063297 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,02934407 0,04060852 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,02934407 0,0405841 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,02934407 0,04055971 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,02934407 0,04053535 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,02934407 0,04051102 ! regulation of coagulation GO:0050818 39 26 0,000 0,02934407 0,04048672 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,03045619 0,04199594 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,03045619 0,04197078 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,03045619 0,04194565 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,03045619 0,04192055 ! membrane docking GO:0022406 39 27 0,000 0,03045619 0,04189548 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,03045619 0,04187043 ! catechol metabolic process GO:0009712 43 27 0,000 0,03045619 0,04184542 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,03045619 0,04182044 ! acute-phase response GO:0006953 42 27 0,000 0,03045619 0,04179549 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,03045619 0,04177056 ! myofibril assembly GO:0030239 36 27 0,000 0,03045619 0,04174567 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,03045619 0,04172081 ! response to ionizing radiation GO:0010212 47 27 0,000 0,03045619 0,04169597 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,03045619 0,04167117 ! natural killer cell activation GO:0030101 35 27 0,000 0,03045619 0,04164639 ! lipid oxidation GO:0034440 38 27 0,000 0,03045619 0,04162165 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,03045619 0,04159693 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,03045619 0,04157225 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,03045619 0,04154759 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,03045619 0,04152296 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,03045619 0,04149836 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,03045619 0,04147379 ! gene silencing GO:0016458 41 27 0,000 0,03045619 0,04144925 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,0315671 0,04293573 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,0315671 0,04291035 ! phenol metabolic process GO:0018958 44 28 0,000 0,0315671 0,04288501 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,0315671 0,04285969 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,0315671 0,04283441 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,0315671 0,04280915 ! cell junction assembly GO:0034329 56 28 0,000 0,0315671 0,04278392 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,0315671 0,04275873 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,0315671 0,04273356 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,0315671 0,04270842 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,0315671 0,04268332 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,0315671 0,04265824 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,0315671 0,04263319 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,0315671 0,04260817 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,0315671 0,04258318 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,0315671 0,04255822 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,0315671 0,04253329 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,0315671 0,04250838 ! mesoderm formation GO:0001707 46 28 0,000 0,0315671 0,04248351 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,0315671 0,04245867 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,0315671 0,04243385 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,0315671 0,04240907 ! ensheathment of neurons GO:0007272 43 28 0,000 0,0315671 0,04238431 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,0315671 0,04235958 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,0315671 0,04233488 ! neural tube formation GO:0001841 41 28 0,000 0,0315671 0,04231021 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,0315671 0,04228557 ! placenta development GO:0001890 37 28 0,000 0,0315671 0,04226095 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,03267679 0,04372113 ! regulation of innate immune response GO:0045088 38 29 0,000 0,03267679 0,04369571 ! ovulation cycle process GO:0022602 41 29 0,000 0,03267679 0,04367032 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,03267679 0,04364496 ! protein targeting to membrane GO:0006612 53 29 0,000 0,03267679 0,04361963 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,03267679 0,04359433 ! mismatch repair GO:0006298 34 29 0,000 0,03267679 0,04356906 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,03267679 0,04354381 ! muscle cell development GO:0055001 38 29 0,000 0,03267679 0,0435186 ! formation of primary germ layer GO:0001704 48 29 0,000 0,03267679 0,04349342 ! telencephalon development GO:0021537 52 29 0,000 0,03267679 0,04346826 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,03267679 0,04344314 ! eye morphogenesis GO:0048592 51 29 0,000 0,03267679 0,04341804 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,03267679 0,04339297 ! tissue homeostasis GO:0001894 42 29 0,000 0,03267679 0,04336793 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,03378528 0,04481324 ! collagen metabolic process GO:0032963 40 30 0,000 0,03378528 0,04478741 ! organic anion transport GO:0015711 51 30 0,000 0,03378528 0,04476161 ! cholesterol transport GO:0030301 46 30 0,000 0,03378528 0,04473584 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,03378528 0,0447101 ! spliceosome assembly GO:0000245 49 30 0,000 0,03378528 0,04468439 ! spindle organization GO:0007051 37 30 0,000 0,03378528 0,04465871 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,03378528 0,04463306 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,03378528 0,04460743 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,03378528 0,04458184 ! ceramide metabolic process GO:0006672 43 30 0,000 0,03378528 0,04455628 ! ovulation cycle GO:0042698 43 30 0,000 0,03378528 0,04453074 ! hindbrain development GO:0030902 45 30 0,000 0,03378528 0,04450524 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,03378528 0,04447977 ! adult locomotory behavior GO:0008344 47 30 0,000 0,03378528 0,04445432 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,03378528 0,0444289 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,03378528 0,04440351 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,03378528 0,04437816 ! response to heat GO:0009408 41 30 0,000 0,03378528 0,04435283 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,03378528 0,04432752 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,03378528 0,04430225 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,03489256 0,04572815 ! negative regulation of secretion GO:0051048 49 31 0,000 0,03489256 0,04570211 ! mammary gland development GO:0030879 57 31 0,000 0,03489256 0,0456761 ! glial cell differentiation GO:0010001 55 31 0,000 0,03489256 0,04565011 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,03489256 0,04562416 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,03489256 0,04559824 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,03489256 0,04557234 ! odontogenesis GO:0042476 50 31 0,000 0,03489256 0,04554648 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,03489256 0,04552065 ! segmentation GO:0035282 41 31 0,000 0,03489256 0,04549484 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,03489256 0,04546906 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,03489256 0,04544332 ! metanephros development GO:0001656 58 31 0,000 0,03489256 0,0454176 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,03489256 0,04539191 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,03489256 0,04536625 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,03489256 0,04534062 ! cell fate specification GO:0001708 37 31 0,000 0,03489256 0,04531502 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,03489256 0,04528945 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,03489256 0,0452639 ! RNA modification GO:0009451 40 31 0,000 0,03489256 0,04523839 ! regulation of muscle development GO:0048634 48 32 0,000 0,03599864 0,04664613 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,03599864 0,04661986 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,03599864 0,04659363 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,03599864 0,04656742 ! meiosis I GO:0007127 52 32 0,000 0,03599864 0,04654125 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,03599864 0,0465151 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,03599864 0,04648898 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,03599864 0,04646289 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,03599864 0,04643683 ! peripheral nervous system development GO:0007422 53 32 0,000 0,03599864 0,04641081 ! regulation of protein stability GO:0031647 48 32 0,000 0,03599864 0,0463848 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,03599864 0,04635883 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,03599864 0,04633289 ! cytokine production GO:0001816 44 32 0,000 0,03599864 0,04630698 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,03599864 0,04628109 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,03599864 0,04625524 ! vesicle localization GO:0051648 47 32 0,000 0,03599864 0,04622941 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,03710351 0,0476217 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,03710351 0,04759514 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,03710351 0,04756861 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,03710351 0,04754211 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,03710351 0,04751564 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,03710351 0,04748919 ! sister chromatid segregation GO:0000819 46 33 0,000 0,03710351 0,04746278 ! ear morphogenesis GO:0042471 42 33 0,000 0,03710351 0,0474364 ! actomyosin structure organization GO:0031032 43 33 0,000 0,03710351 0,04741005 ! cell junction organization GO:0034330 63 33 0,000 0,03710351 0,04738372 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,03710351 0,04735743 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,03710351 0,04733116 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,03710351 0,04730492 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,03710351 0,04727872 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,03710351 0,04725254 ! female gonad development GO:0008585 49 33 0,000 0,03710351 0,04722639 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,03710351 0,04720027 ! positive regulation of cell development GO:0010720 54 33 0,000 0,03710351 0,04717418 ! lipid homeostasis GO:0055088 55 33 0,000 0,03710351 0,04714811 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,03710351 0,04712208 ! regulation of proteolysis GO:0030162 50 33 0,000 0,03710351 0,04709607 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,03710351 0,0470701 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,03710351 0,04704415 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,03710351 0,04701823 ! cytokinesis GO:0000910 52 33 0,000 0,03710351 0,04699234 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,03710351 0,04696647 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,03820718 0,04833692 ! mRNA catabolic process GO:0006402 48 34 0,000 0,03820718 0,04831035 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,03820718 0,0482838 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,03820718 0,04825729 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,03820718 0,0482308 ! feeding behavior GO:0007631 45 34 0,000 0,03820718 0,04820435 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,03820718 0,04817792 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,03820718 0,04815152 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,03820718 0,04812515 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,03820718 0,04809881 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,03820718 0,0480725 ! neuron migration GO:0001764 46 34 0,000 0,03820718 0,04804621 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,03820718 0,04801996 ! female gamete generation GO:0007292 43 34 0,000 0,03820718 0,04799373 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,03820718 0,04796753 ! polyol metabolic process GO:0019751 44 34 0,000 0,03820718 0,04794137 ! aerobic respiration GO:0009060 47 34 0,000 0,03820718 0,04791523 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,03820718 0,04788911 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,03820718 0,04786303 ! embryonic organ development GO:0048568 45 34 0,000 0,03820718 0,04783698 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,03820718 0,04781095 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,03930965 0,04916378 ! Notch signaling pathway GO:0007219 56 35 0,000 0,03930965 0,04913706 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,03930965 0,04911037 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,03930965 0,04908371 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,03930965 0,04905708 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,03930965 0,04903048 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,03930965 0,0490039 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,03930965 0,04897736 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,03930965 0,04895084 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,03930965 0,04892435 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,03930965 0,04889789 ! glycogen metabolic process GO:0005977 48 35 0,000 0,03930965 0,04887146 ! pigment metabolic process GO:0042440 61 35 0,000 0,03930965 0,04884506 ! protein homooligomerization GO:0051260 52 35 0,000 0,03930965 0,04881868 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,04041092 0,05015926 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,04041092 0,05013221 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,04041092 0,05010518 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,04041092 0,05007819 ! negative regulation of binding GO:0051100 58 36 0,000 0,04041092 0,05005122 ! organic ether metabolic process GO:0018904 46 36 0,000 0,04041092 0,05002428 ! tissue remodeling GO:0048771 62 36 0,000 0,04041092 0,04999737 ! neural tube development GO:0021915 50 36 0,000 0,04041092 0,04997049 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,04041092 0,04994364 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,04041092 0,04991682 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,04041092 0,04989002 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,04041092 0,04986326 ! glucan metabolic process GO:0044042 49 36 0,000 0,04041092 0,04983652 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,04151099 0,05116574 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,04151099 0,05113833 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,04151099 0,05111096 ! learning GO:0007612 67 37 0,000 0,04151099 0,05108361 ! ion transmembrane transport GO:0034220 56 37 0,000 0,04151099 0,05105629 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,04151099 0,05102901 ! regulation of protein secretion GO:0050708 51 37 0,000 0,04151099 0,05100175 ! amino acid activation GO:0043038 52 37 0,000 0,04151099 0,05097452 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,04151099 0,05094732 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,04260986 0,05226809 ! gliogenesis GO:0042063 71 38 0,000 0,04260986 0,05224023 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,04260986 0,0522124 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,04260986 0,05218459 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,04260986 0,05215682 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,04260986 0,05212908 ! phagocytosis GO:0006909 60 38 0,000 0,04260986 0,05210137 ! mesenchymal cell development GO:0014031 64 38 0,000 0,04260986 0,05207368 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,04260986 0,05204603 ! maintenance of location in cell GO:0051651 69 38 0,000 0,04260986 0,0520184 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,04370753 0,05333014 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,04370753 0,05330186 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,04370753 0,05327362 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,04370753 0,0532454 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,04370753 0,05321721 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,04370753 0,05318906 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,04370753 0,05316093 ! male sex differentiation GO:0046661 53 39 0,000 0,04370753 0,05313283 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,04370753 0,05310476 ! chromatin remodeling GO:0006338 68 39 0,000 0,04370753 0,05307672 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,04370753 0,05304872 ! JNK cascade GO:0007254 54 39 0,000 0,04370753 0,05302074 ! developmental growth GO:0048589 62 39 0,000 0,04370753 0,05299279 ! cell growth GO:0016049 61 39 0,000 0,04370753 0,05296487 ! synapse organization GO:0050808 55 39 0,000 0,04370753 0,05293698 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,04480401 0,05423643 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,04480401 0,0542079 ! regulation of tube size GO:0035150 60 40 0,000 0,04480401 0,0541794 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,04480401 0,05415093 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,04480401 0,05412249 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,04480401 0,05409408 ! peptide metabolic process GO:0006518 56 40 0,000 0,04480401 0,05406569 ! inner ear development GO:0048839 57 40 0,000 0,04480401 0,05403734 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,04480401 0,05400902 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,04480401 0,05398073 ! double-strand break repair GO:0006302 67 40 0,000 0,04480401 0,05395247 ! B cell differentiation GO:0030183 62 40 0,000 0,04480401 0,05392424 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,04480401 0,05389603 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,04480401 0,05386786 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,04480401 0,05383971 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,04480401 0,0538116 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,04589929 0,05509831 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,04589929 0,05506957 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,04589929 0,05504086 ! glucose transport GO:0015758 52 41 0,000 0,04589929 0,05501217 ! endosome transport GO:0016197 71 41 0,000 0,04589929 0,05498352 ! striated muscle contraction GO:0006941 62 41 0,000 0,04589929 0,0549549 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,04589929 0,05492631 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,04589929 0,05489774 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,04589929 0,05486921 ! biopolymer methylation GO:0043414 62 41 0,000 0,04589929 0,05484071 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,04589929 0,05481223 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,04699338 0,05608966 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,04699338 0,05606057 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,04699338 0,0560315 ! cellular component disassembly GO:0022411 64 42 0,000 0,04699338 0,05600247 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,04699338 0,05597347 ! hexose transport GO:0008645 54 42 0,000 0,04699338 0,0559445 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,04699338 0,05591556 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,04699338 0,05588664 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,04699338 0,05585776 ! excretion GO:0007588 63 42 0,000 0,04699338 0,05582891 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,04699338 0,05580009 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,04699338 0,05577129 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,04699338 0,05574253 ! regulation of cell shape GO:0008360 78 42 0,000 0,04699338 0,0557138 ! positive regulation of binding GO:0051099 59 43 0,000 0,04808628 0,05698013 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,04808628 0,05695079 ! leukocyte migration GO:0050900 60 43 0,000 0,04808628 0,05692148 ! neuromuscular process GO:0050905 79 43 0,000 0,04808628 0,0568922 ! activation of caspase activity GO:0006919 65 43 0,000 0,04808628 0,05686295 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,04808628 0,05683373 ! tRNA processing GO:0008033 49 43 0,000 0,04808628 0,05680454 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,04808628 0,05677538 ! vesicle organization GO:0016050 79 43 0,000 0,04808628 0,05674625 ! response to insulin stimulus GO:0032868 63 43 0,000 0,04808628 0,05671715 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,04808628 0,05668807 ! methylation GO:0032259 64 43 0,000 0,04808628 0,05665903 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,04917798 0,0579157 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,04917798 0,05788606 ! glycolysis GO:0006096 53 44 0,000 0,04917798 0,05785645 ! regulation of action potential GO:0001508 71 44 0,000 0,04917798 0,05782687 ! regulation of ion transport GO:0043269 57 44 0,000 0,04917798 0,05779732 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,04917798 0,0577678 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,04917798 0,05773832 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,04917798 0,05770886 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,04917798 0,05767943 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,04917798 0,05765003 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,04917798 0,05762066 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,04917798 0,05759132 ! RNA catabolic process GO:0006401 64 45 0,000 0,0502685 0,05883845 ! positive regulation of defense response GO:0031349 59 45 0,000 0,0502685 0,05880852 ! regulation of translational initiation GO:0006446 64 45 0,000 0,0502685 0,05877862 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,0502685 0,05874875 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,0502685 0,05871892 ! cell recognition GO:0008037 58 45 0,000 0,0502685 0,05868911 ! cell maturation GO:0048469 60 45 0,000 0,0502685 0,05865933 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,0502685 0,05862959 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,05135783 0,05986974 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,05135783 0,05983942 ! cell redox homeostasis GO:0045454 63 46 0,000 0,05135783 0,05980912 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,05135783 0,05977885 ! regulation of ossification GO:0030278 71 46 0,000 0,05135783 0,05974861 ! histone modification GO:0016570 68 46 0,000 0,05135783 0,05971841 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,05135783 0,05968823 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,05244597 0,06092209 ! viral infectious cycle GO:0019058 71 47 0,000 0,05244597 0,06089133 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,05244597 0,06086061 ! endocrine system development GO:0035270 83 47 0,000 0,05244597 0,06082992 ! covalent chromatin modification GO:0016569 75 47 0,000 0,05244597 0,06079926 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,05244597 0,06076863 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,05244597 0,06073803 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,05244597 0,06070746 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,05244597 0,06067693 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,05244597 0,06064642 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,05244597 0,06061595 ! chloride transport GO:0006821 67 48 0,000 0,05353293 0,06184115 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,05353293 0,06181011 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,05353293 0,06177909 ! response to temperature stimulus GO:0009266 62 48 0,000 0,05353293 0,06174811 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,05353293 0,06171716 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,05353293 0,06168624 ! gastrulation GO:0007369 73 48 0,000 0,05353293 0,06165535 ! heart morphogenesis GO:0003007 65 48 0,000 0,05353293 0,06162449 ! regulation of DNA replication GO:0006275 75 48 0,000 0,05353293 0,06159366 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,05353293 0,06156287 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,05353293 0,0615321 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,05353293 0,06150136 ! regulation of endocytosis GO:0030100 63 48 0,000 0,05353293 0,06147066 ! nuclear export GO:0051168 69 48 0,000 0,05353293 0,06143999 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,05353293 0,06140934 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,05353293 0,06137873 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,0546187 0,06259243 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,0546187 0,06256126 ! sensory perception of smell GO:0007608 61 49 0,000 0,0546187 0,06253012 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,0546187 0,06249901 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,0546187 0,06246793 ! RNA elongation GO:0006354 62 49 0,000 0,0546187 0,06243688 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,0546187 0,06240586 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,0546187 0,06237488 ! germ cell development GO:0007281 68 49 0,000 0,0546187 0,06234392 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,0546187 0,062313 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,0546187 0,06228211 ! cartilage development GO:0051216 70 49 0,000 0,0546187 0,06225124 ! maintenance of location GO:0051235 84 49 0,000 0,0546187 0,06222041 ! regulation of actin filament length GO:0030832 72 50 0,000 0,05570329 0,06342453 ! ear development GO:0043583 72 50 0,000 0,05570329 0,06339315 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,05570329 0,0633618 ! membrane fusion GO:0006944 80 50 0,000 0,05570329 0,06333048 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,05570329 0,06329919 ! lipid modification GO:0030258 73 50 0,000 0,05570329 0,06326793 ! positive regulation of growth GO:0045927 67 50 0,000 0,05570329 0,0632367 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,05570329 0,06320551 ! proton transport GO:0015992 75 50 0,000 0,05570329 0,06317434 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,05570329 0,0631432 ! positive regulation of secretion GO:0051047 71 51 0,000 0,05678669 0,0643396 ! hydrogen transport GO:0006818 77 51 0,000 0,05678669 0,06430792 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,05678669 0,06427628 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,05678669 0,06424466 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,05678669 0,06421307 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,05678669 0,06418152 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,05678669 0,06415 ! adult behavior GO:0030534 80 51 0,000 0,05678669 0,0641185 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,05678669 0,06408704 ! transition metal ion transport GO:0000041 74 52 0,000 0,05786892 0,06527637 ! regulation of cellular component size GO:0032535 74 52 0,000 0,05786892 0,06524437 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,05786892 0,0652124 ! aging GO:0007568 79 52 0,000 0,05786892 0,06518047 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,05786892 0,06514856 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,05786892 0,06511669 ! establishment of organelle localization GO:0051656 85 52 0,000 0,05786892 0,06508485 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,05894996 0,06626829 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,05894996 0,06623591 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,05894996 0,06620357 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,05894996 0,06617126 ! kidney development GO:0001822 90 53 0,000 0,05894996 0,06613898 ! single fertilization GO:0007338 59 53 0,000 0,05894996 0,06610674 ! cell projection assembly GO:0030031 76 53 0,000 0,05894996 0,06607452 ! amino acid transport GO:0006865 84 54 0,000 0,06002983 0,06725212 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,06002983 0,06721938 ! regulation of mitosis GO:0007088 84 54 0,000 0,06002983 0,06718667 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,06002983 0,06715399 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,06002983 0,06712135 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,06002983 0,06708873 ! DNA catabolic process GO:0006308 67 54 0,000 0,06002983 0,06705615 ! detection of external stimulus GO:0009581 66 54 0,000 0,06002983 0,0670236 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,06002983 0,06699108 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,06002983 0,06695859 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,06002983 0,06692613 ! exocytosis GO:0006887 74 55 0,000 0,06110852 0,06809573 ! mesoderm development GO:0007498 76 55 0,000 0,06110852 0,06806276 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,06110852 0,06802981 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,06110852 0,0679969 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,06218603 0,06916242 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,06218603 0,06912899 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,06218603 0,06909559 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,06218603 0,06906223 ! carbohydrate transport GO:0008643 74 57 0,000 0,06326237 0,07022368 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,06326237 0,0701898 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,06326237 0,07015596 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,06326237 0,07012215 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,06326237 0,07008837 ! camera-type eye development GO:0043010 88 57 0,000 0,06326237 0,07005462 ! secondary metabolic process GO:0019748 84 57 0,000 0,06326237 0,07002091 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,06326237 0,06998723 ! developmental maturation GO:0021700 75 57 0,000 0,06326237 0,06995358 ! gonad development GO:0008406 79 57 0,000 0,06326237 0,06991997 ! viral reproductive process GO:0022415 87 58 0,000 0,06433754 0,07107413 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,06433754 0,07104001 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,06433754 0,07100592 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,06433754 0,07097186 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,06541153 0,07212201 ! activation of MAPK activity GO:0000187 84 59 0,000 0,06541153 0,07208746 ! lung development GO:0030324 94 59 0,000 0,06541153 0,07205293 ! actin filament organization GO:0007015 95 59 0,000 0,06541153 0,07201844 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,06541153 0,07198398 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,06541153 0,07194955 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,06648435 0,07309465 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,06648435 0,07305973 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,06648435 0,07302484 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,06648435 0,07298998 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,06648435 0,07295516 ! regulation of heart contraction GO:0008016 91 60 0,000 0,06648435 0,07292037 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,06648435 0,07288561 ! fertilization GO:0009566 68 60 0,000 0,06648435 0,07285089 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,06648435 0,07281619 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,067556 0,07395469 ! meiosis GO:0007126 96 61 0,000 0,067556 0,07391951 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,067556 0,07388436 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,067556 0,07384924 ! urogenital system development GO:0001655 101 61 0,000 0,067556 0,07381416 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,067556 0,07377911 ! extracellular matrix organization GO:0030198 103 61 0,000 0,067556 0,07374409 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,067556 0,07370911 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,067556 0,07367416 ! amine catabolic process GO:0009310 90 62 0,000 0,06862649 0,07480612 ! neurotransmitter transport GO:0006836 81 62 0,000 0,06862649 0,07477069 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,06862649 0,07473528 ! respiratory tube development GO:0030323 99 62 0,000 0,06862649 0,07469991 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,06862649 0,07466458 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,06862649 0,07462928 ! meiotic cell cycle GO:0051321 97 62 0,000 0,06862649 0,07459401 ! organelle localization GO:0051640 96 62 0,000 0,06862649 0,07455877 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,0696958 0,07568477 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,0696958 0,07564905 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,0696958 0,07561337 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,0696958 0,07557772 ! viral reproduction GO:0016032 92 63 0,000 0,0696958 0,0755421 ! regulation of lipase activity GO:0060191 109 63 0,000 0,0696958 0,07550652 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,07076395 0,07662763 ! appendage morphogenesis GO:0035107 93 64 0,000 0,07076395 0,07659157 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,07076395 0,07655554 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,07076395 0,07651955 ! hexose catabolic process GO:0019320 82 64 0,000 0,07076395 0,07648359 ! respiratory system development GO:0060541 100 64 0,000 0,07076395 0,07644767 ! adaptive immune response GO:0002250 94 64 0,000 0,07076395 0,07641178 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,07183093 0,07752752 ! regulation of caspase activity GO:0043281 97 65 0,000 0,07183093 0,07749116 ! appendage development GO:0048736 94 65 0,000 0,07183093 0,07745483 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,07183093 0,07741853 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,07183093 0,07738227 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,07183093 0,07734604 ! defense response to bacterium GO:0042742 73 65 0,000 0,07183093 0,07730985 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,07183093 0,07727369 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,07183093 0,07723756 ! activation of immune response GO:0002253 83 65 0,000 0,07183093 0,07720147 ! protein oligomerization GO:0051259 100 65 0,000 0,07183093 0,07716541 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,07289675 0,07827382 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,07289675 0,0782373 ! antigen processing and presentation GO:0019882 96 66 0,000 0,07289675 0,07820081 ! axon guidance GO:0007411 99 66 0,000 0,07289675 0,07816435 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,07289675 0,07812793 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,07396141 0,07923206 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,07396141 0,07919518 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,07396141 0,07915833 ! acute inflammatory response GO:0002526 92 68 0,000 0,07502491 0,0802592 ! learning or memory GO:0007611 123 68 0,000 0,07502491 0,08022189 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,07502491 0,08018461 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,07502491 0,08014737 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,07502491 0,08011016 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,07502491 0,08007298 ! rhythmic process GO:0048511 105 68 0,000 0,07502491 0,08003585 ! inorganic anion transport GO:0015698 93 68 0,000 0,07502491 0,07999874 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,07608724 0,08109391 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,07608724 0,08105635 ! response to drug GO:0042493 108 69 0,000 0,07608724 0,08101882 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,07608724 0,08098133 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,07714842 0,08207278 ! humoral immune response GO:0006959 86 70 0,000 0,07714842 0,08203484 ! eye development GO:0001654 111 70 0,000 0,07714842 0,08199693 ! amine transport GO:0015837 101 70 0,000 0,07714842 0,08195906 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,07714842 0,08192122 ! regulation of catabolic process GO:0009894 106 70 0,000 0,07714842 0,08188341 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,07820843 0,0829702 ! muscle cell differentiation GO:0042692 104 71 0,000 0,07820843 0,08293195 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,07820843 0,08289373 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,07820843 0,08285555 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,07820843 0,0828174 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,07820843 0,08277929 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,07820843 0,08274121 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,0792673 0,08382289 ! response to hypoxia GO:0001666 132 72 0,000 0,0792673 0,08378437 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,0792673 0,08374588 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,0792673 0,08370743 ! negative regulation of transport GO:0051051 116 73 0,000 0,080325 0,08478545 ! regulation of blood pressure GO:0008217 107 73 0,000 0,080325 0,08474656 ! tube morphogenesis GO:0035239 118 73 0,000 0,080325 0,0847077 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,080325 0,08466888 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,080325 0,0846301 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,08138155 0,08570402 ! response to oxygen levels GO:0070482 137 74 0,000 0,08138155 0,08566479 ! digestion GO:0007586 97 74 0,000 0,08138155 0,0856256 ! protein import into nucleus GO:0006606 118 74 0,000 0,08138155 0,08558645 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,08138155 0,08554734 ! blood coagulation GO:0007596 116 75 0,000 0,08243695 0,08661717 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,08243695 0,08657762 ! regulation of ligase activity GO:0051340 114 75 0,000 0,08243695 0,0865381 ! nuclear import GO:0051170 121 75 0,000 0,08243695 0,08649862 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,08243695 0,08645918 ! amine biosynthetic process GO:0009309 97 76 0,000 0,0834912 0,08752495 ! tRNA metabolic process GO:0006399 95 76 0,000 0,0834912 0,08748508 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,0834912 0,08744524 ! regulation of protein transport GO:0051223 114 76 0,000 0,0834912 0,08740544 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,08454429 0,08846764 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,08454429 0,08842741 ! regulation of DNA binding GO:0051101 119 77 0,000 0,08454429 0,08838721 ! gland development GO:0048732 148 77 0,000 0,08454429 0,08834706 ! sex differentiation GO:0007548 105 77 0,000 0,08454429 0,08830693 ! protein ubiquitination GO:0016567 125 77 0,000 0,08454429 0,08826685 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,08454429 0,0882268 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,08454429 0,08818679 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,08454429 0,08814681 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,08559624 0,08920315 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,08559624 0,08916275 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,08664703 0,09021647 ! cellular respiration GO:0045333 107 79 0,000 0,08664703 0,09017565 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,08664703 0,09013486 ! T cell activation GO:0042110 134 79 0,000 0,08664703 0,09009411 ! regulation of lyase activity GO:0051339 133 79 0,000 0,08664703 0,0900534 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,08664703 0,09001273 ! chromatin assembly GO:0031497 102 80 0,000 0,08769668 0,09106202 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,08769668 0,09102093 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,08769668 0,09097987 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,08769668 0,09093885 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,08769668 0,09089787 ! forebrain development GO:0030900 131 80 0,000 0,08769668 0,09085693 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,08874519 0,09190182 ! hemostasis GO:0007599 125 81 0,000 0,08874519 0,09186046 ! mRNA transport GO:0051028 121 81 0,000 0,08874519 0,09181913 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,08874519 0,09177785 ! regulation of neurological system process GO:0031644 122 81 0,000 0,08874519 0,0917366 ! vitamin metabolic process GO:0006766 103 81 0,000 0,08874519 0,09169539 ! ossification GO:0001503 134 82 0,000 0,08979255 0,0927359 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,08979255 0,09269428 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,09083876 0,09373224 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,09083876 0,0936902 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,09083876 0,09364821 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,09188384 0,09468316 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,09188384 0,09464076 ! sterol metabolic process GO:0016125 120 84 0,000 0,09188384 0,0945984 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,09292777 0,09563036 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,09292777 0,0955876 ! rRNA metabolic process GO:0016072 107 85 0,000 0,09292777 0,09554487 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,09292777 0,09550217 ! transcription initiation GO:0006352 118 85 0,000 0,09292777 0,09545952 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,09292777 0,0954169 ! regulation of protein localization GO:0032880 132 85 0,000 0,09292777 0,09537433 ! regulation of membrane potential GO:0042391 128 85 0,000 0,09292777 0,09533179 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,09292777 0,09528928 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,09397056 0,09631564 ! nucleosome organization GO:0034728 114 87 0,000 0,09501221 0,0973399 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,09501221 0,09729657 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,09501221 0,09725327 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,09501221 0,09721 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,09501221 0,09716678 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,09501221 0,09712359 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,09605273 0,09814361 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,09605273 0,09810003 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,09605273 0,09805649 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,09605273 0,09801299 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,09605273 0,09796952 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,0970921 0,09898575 ! reproductive developmental process GO:0003006 127 89 0,000 0,0970921 0,09894189 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,0970921 0,09889807 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,0970921 0,09885429 ! regulation of T cell activation GO:0050863 128 89 0,000 0,0970921 0,09881055 ! leukocyte differentiation GO:0002521 143 90 0,000 0,09813035 0,099823 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,09813035 0,09977887 ! hormone metabolic process GO:0042445 121 90 0,000 0,09813035 0,09973478 ! RNA localization GO:0006403 135 91 0,000 0,09916746 0,10074432 ! ATP metabolic process GO:0046034 137 91 0,000 0,09916746 0,10069985 ! response to virus GO:0009615 122 91 0,000 0,09916746 0,10065541 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,10020343 0,10166206 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,10020343 0,10161724 ! cell fate commitment GO:0045165 141 92 0,000 0,10020343 0,10157245 ! positive regulation of immune response GO:0050778 121 92 0,000 0,10020343 0,10152771 ! DNA recombination GO:0006310 146 92 0,000 0,10020343 0,101483 ! sulfur metabolic process GO:0006790 118 92 0,000 0,10020343 0,10143833 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,10123828 0,10244084 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,10123828 0,10239579 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,10123828 0,10235078 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,10123828 0,10230581 ! electron transport chain GO:0022900 123 94 0,000 0,10227199 0,10330504 ! response to oxidative stress GO:0006979 141 94 0,000 0,10227199 0,10325969 ! regulation of binding GO:0051098 151 95 0,000 0,10330457 0,10425648 ! angiogenesis GO:0001525 149 95 0,000 0,10330457 0,10421075 ! carboxylic acid transport GO:0046942 147 95 0,000 0,10330457 0,10416507 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,10433603 0,10515901 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,10433603 0,10511295 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,10433603 0,10506693 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,10433603 0,10502095 ! protein maturation GO:0051604 129 96 0,000 0,10433603 0,10497501 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,10536635 0,10596529 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,10536635 0,10591898 ! calcium ion transport GO:0006816 167 99 0,000 0,10742363 0,10793987 ! extracellular structure organization GO:0043062 156 99 0,000 0,10742363 0,10789273 ! protein import GO:0017038 156 99 0,000 0,10742363 0,10784564 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,10742363 0,10779858 ! regulation of translation GO:0006417 151 100 0,000 0,10845059 0,10878166 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,10845059 0,10873424 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,10845059 0,10868686 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,10845059 0,10863952 ! divalent metal ion transport GO:0070838 171 100 0,000 0,10845059 0,10859223 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,10845059 0,10854497 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,10845059 0,10849776 ! protein localization in organelle GO:0033365 161 100 0,000 0,10845059 0,10845059